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Gene: MMAR_3711

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General annotation
Gene namecysH
Accession numberMMAR_3711
TypeCDS
Functioninvolved in the sulfate activation pathway (at the third step) in the reductive branch of the cysteine biosynthetic pathway. reduces activated sulfate into sulfite [catalytic activity: 5-phosphoadenosine 3-phosphosulfate + reduced thioredoxin = phosphoadenosine phosphate + oxidized thioredoxin + sulfite].
Product3'-phosphoadenosine 5'-phosphosulfate reductase CysH
Topology predictionCytosolic
Molecular mass (Da)26681.1
Isoelectric point4.78
Gene length (bp)750
Protein length250
Location (kb)4571.3


Functional categoryintermediary metabolism and respiration


Coordinates
TypeStartEndOrientation
CDS45713004572049+


Protein sequence in FASTA format
>M. marinum M | cysH
MIETSNLTEAELRELAARGAAELEGASATELLQWTDETFGGANRAAGVAGVQTANYVVASNMQDAVLIDLASKVRPGVPV
LFLDTGYHFAETIGSRDAVESVYDVQVLTITPEHTVAEQDKLLGKDLFARDPGECCRLRKVVPLRQALSNFSAWVTGLRR
VEAPTRANAPVISFDEAFKLVKINPLAAWSDDEVQDYIVANNVLVNPLVDEGYPSIGCAPCTVKPAAGADPRSGRWQGLA
KTECGLHAS*
Blastp: results
TransMembrane prediction using Hidden Markov Models: tmhmm
Microbe Genome Browser
Genomic sequence

Add extra bases upstream (5') and downstream (3')



Structural information
Protein Data BankNo structure available
PFAMProtein Family Domains


Orthologs/Cross-references
Gene Ontologyphosphoadenylyl-sulfate reductase (thioredoxin) activity
transferase activity
cysteine biosynthetic process
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
oxidation reduction
MtuberculosisRv2392
UniProtB2HMA7