BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0006 Length=838 Score E Sequences producing significant alignments: (Bits) Value gi|15607148|ref|NP_214520.1| DNA gyrase subunit A [Mycobacterium... 1686 0.0 gi|306778294|ref|ZP_07416631.1| DNA gyrase subunit A gyrA [Mycob... 1684 0.0 gi|1346235|sp|Q07702.2|GYRA_MYCTU RecName: Full=DNA gyrase subun... 1684 0.0 gi|15839378|ref|NP_334415.1| DNA gyrase subunit A [Mycobacterium... 1682 0.0 gi|339630089|ref|YP_004721731.1| DNA gyrase subunit A [Mycobacte... 1680 0.0 gi|334265274|gb|AEG75288.1| DNA gyrase alpha subunit [Mycobacter... 1680 0.0 gi|253796921|ref|YP_003029922.1| DNA gyrase subunit A gyrA [Myco... 1680 0.0 gi|289567888|ref|ZP_06448115.1| DNA gyrase subunit A gyrA [Mycob... 1680 0.0 gi|334265278|gb|AEG75290.1| DNA gyrase alpha subunit [Mycobacter... 1678 0.0 gi|334265272|gb|AEG75287.1| DNA gyrase alpha subunit [Mycobacter... 1678 0.0 gi|289552256|ref|ZP_06441466.1| DNA gyrase subunit A gyrA [Mycob... 1678 0.0 gi|31791183|ref|NP_853676.1| DNA gyrase subunit A [Mycobacterium... 1678 0.0 gi|334265276|gb|AEG75289.1| DNA gyrase alpha subunit [Mycobacter... 1677 0.0 gi|336459821|gb|EGO38735.1| DNA gyrase, A subunit [Mycobacterium... 1586 0.0 gi|183980041|ref|YP_001848332.1| DNA gyrase (subunit A) GyrA [My... 1584 0.0 gi|41406104|ref|NP_958940.1| DNA gyrase subunit A [Mycobacterium... 1584 0.0 gi|342862358|ref|ZP_08718999.1| DNA gyrase subunit A [Mycobacter... 1576 0.0 gi|118615925|ref|YP_904257.1| DNA gyrase subunit A [Mycobacteriu... 1575 0.0 gi|206148715|gb|ACI05548.1| GyrA [Mycobacterium indicus pranii] 1569 0.0 gi|118462773|ref|YP_879309.1| DNA gyrase subunit A [Mycobacteriu... 1568 0.0 gi|254773059|ref|ZP_05214575.1| DNA gyrase subunit A [Mycobacter... 1566 0.0 gi|289441373|ref|ZP_06431117.1| DNA gyrase, A subunit [Mycobacte... 1541 0.0 gi|126432620|ref|YP_001068311.1| DNA gyrase subunit A [Mycobacte... 1538 0.0 gi|118467811|ref|YP_884429.1| DNA gyrase subunit A [Mycobacteriu... 1535 0.0 gi|169627127|ref|YP_001700776.1| DNA gyrase subunit A [Mycobacte... 1526 0.0 gi|1226022|emb|CAA58885.1| DNA gyrase [Mycobacterium smegmatis] 1498 0.0 gi|226303499|ref|YP_002763457.1| DNA gyrase subunit A [Rhodococc... 1443 0.0 gi|229491128|ref|ZP_04384956.1| DNA gyrase, A subunit [Rhodococc... 1442 0.0 gi|111020669|ref|YP_703641.1| DNA gyrase subunit A [Rhodococcus ... 1434 0.0 gi|226362909|ref|YP_002780689.1| DNA gyrase subunit A [Rhodococc... 1433 0.0 gi|54021971|ref|YP_116213.1| DNA gyrase subunit A [Nocardia farc... 1432 0.0 gi|296137760|ref|YP_003645003.1| DNA gyrase subunit alpha [Tsuka... 1418 0.0 gi|312137524|ref|YP_004004860.1| DNA gyrase subunit a [Rhodococc... 1417 0.0 gi|343928740|ref|ZP_08768185.1| DNA gyrase subunit A [Gordonia a... 1389 0.0 gi|262200052|ref|YP_003271260.1| DNA gyrase subunit A [Gordonia ... 1384 0.0 gi|333917685|ref|YP_004491266.1| DNA topoisomerase subunit A [Am... 1377 0.0 gi|154795731|gb|ABS86853.1| gyrase A [Mycobacterium avium subsp.... 1369 0.0 gi|296392547|ref|YP_003657431.1| DNA gyrase subunit A [Segnilipa... 1366 0.0 gi|326383915|ref|ZP_08205599.1| DNA gyrase subunit A [Gordonia n... 1354 0.0 gi|154795735|gb|ABS86855.1| gyrase A [Mycobacterium avium subsp.... 1348 0.0 gi|240172097|ref|ZP_04750756.1| DNA gyrase subunit A [Mycobacter... 1330 0.0 gi|317509460|ref|ZP_07967078.1| DNA gyrase, subunit A [Segnilipa... 1329 0.0 gi|331693905|ref|YP_004330144.1| DNA gyrase subunit A [Pseudonoc... 1319 0.0 gi|324999888|ref|ZP_08121000.1| DNA gyrase subunit A [Pseudonoca... 1309 0.0 gi|300781944|ref|YP_003762235.1| DNA gyrase subunit A [Amycolato... 1303 0.0 gi|296167138|ref|ZP_06849545.1| DNA topoisomerase (ATP-hydrolyzi... 1302 0.0 gi|254820902|ref|ZP_05225903.1| DNA gyrase, A subunit [Mycobacte... 1300 0.0 gi|256374167|ref|YP_003097827.1| DNA gyrase subunit A [Actinosyn... 1290 0.0 gi|257054096|ref|YP_003131928.1| DNA gyrase subunit A [Saccharom... 1286 0.0 gi|134096627|ref|YP_001102288.1| DNA gyrase subunit A [Saccharop... 1284 0.0 >gi|15607148|ref|NP_214520.1| DNA gyrase subunit A [Mycobacterium tuberculosis H37Rv] gi|148659763|ref|YP_001281286.1| DNA gyrase subunit A [Mycobacterium tuberculosis H37Ra] gi|167969469|ref|ZP_02551746.1| DNA gyrase subunit A [Mycobacterium tuberculosis H37Ra] gi|307086732|ref|ZP_07495845.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu012] gi|1552559|emb|CAB02427.1| DNA GYRASE (SUBUNIT A) GYRA (DNA TOPOISOMERASE (ATP-HYDROLYSING)) (DNA TOPOISOMERASE II) (TYPE II DNA TOPOISOMERASE) [Mycobacterium tuberculosis H37Rv] gi|148503915|gb|ABQ71724.1| DNA gyrase subunit A [Mycobacterium tuberculosis H37Ra] gi|308363882|gb|EFP52733.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu012] Length=838 Score = 1686 bits (4365), Expect = 0.0, Method: Compositional matrix adjust. Identities = 838/838 (100%), Positives = 838/838 (100%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|306778294|ref|ZP_07416631.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu001] gi|306974413|ref|ZP_07487074.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu010] gi|307082121|ref|ZP_07491291.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu011] gi|308213444|gb|EFO72843.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu001] gi|308356308|gb|EFP45159.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu010] gi|308360195|gb|EFP49046.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis SUMu011] Length=838 Score = 1684 bits (4361), Expect = 0.0, Method: Compositional matrix adjust. Identities = 837/838 (99%), Positives = 838/838 (100%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|1346235|sp|Q07702.2|GYRA_MYCTU RecName: Full=DNA gyrase subunit A gi|466275|gb|AAA83017.1| gyrase A [Mycobacterium tuberculosis H37Rv] Length=838 Score = 1684 bits (4361), Expect = 0.0, Method: Compositional matrix adjust. Identities = 837/838 (99%), Positives = 838/838 (100%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRL+SLNVVREG Sbjct 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLVSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|15839378|ref|NP_334415.1| DNA gyrase subunit A [Mycobacterium tuberculosis CDC1551] gi|121635889|ref|YP_976112.1| DNA gyrase subunit A [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|121635916|ref|YP_976139.1| DNA gyrase subunit A [Mycobacterium bovis BCG str. Pasteur 1173P2] 48 more sequence titles Length=838 Score = 1682 bits (4356), Expect = 0.0, Method: Compositional matrix adjust. Identities = 835/838 (99%), Positives = 837/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|339630089|ref|YP_004721731.1| DNA gyrase subunit A [Mycobacterium africanum GM041182] gi|339329445|emb|CCC25080.1| DNA gyrase (subunit A) [Mycobacterium africanum GM041182] Length=838 Score = 1680 bits (4352), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKA DALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKAFDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|334265274|gb|AEG75288.1| DNA gyrase alpha subunit [Mycobacterium tuberculosis] Length=838 Score = 1680 bits (4351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGD SIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDVSIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|253796921|ref|YP_003029922.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis KZN 1435] gi|297632474|ref|ZP_06950254.1| DNA gyrase subunit A [Mycobacterium tuberculosis KZN 4207] gi|313656772|ref|ZP_07813652.1| DNA gyrase subunit A [Mycobacterium tuberculosis KZN V2475] gi|253318424|gb|ACT23027.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis KZN 1435] gi|328456712|gb|AEB02135.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis KZN 4207] gi|344217824|gb|AEM98454.1| DNA gyrase subunit A [Mycobacterium tuberculosis CTRI-2] Length=838 Score = 1680 bits (4351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKT RGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTSRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|289567888|ref|ZP_06448115.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis T17] gi|289748468|ref|ZP_06507846.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis T92] gi|289756065|ref|ZP_06515443.1| subunit A gyrA [Mycobacterium tuberculosis EAS054] gi|289541641|gb|EFD45290.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis T17] gi|289689055|gb|EFD56484.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis T92] gi|289696652|gb|EFD64081.1| subunit A gyrA [Mycobacterium tuberculosis EAS054] Length=838 Score = 1680 bits (4351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRK NERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKVNERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|334265278|gb|AEG75290.1| DNA gyrase alpha subunit [Mycobacterium tuberculosis] gi|339296735|gb|AEJ48845.1| DNA gyrase subunit A [Mycobacterium tuberculosis CCDC5180] Length=838 Score = 1678 bits (4346), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIY +LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYGTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|334265272|gb|AEG75287.1| DNA gyrase alpha subunit [Mycobacterium tuberculosis] Length=838 Score = 1678 bits (4346), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIY +LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYATLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|289552256|ref|ZP_06441466.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis KZN 605] gi|297729443|ref|ZP_06958561.1| DNA gyrase subunit A [Mycobacterium tuberculosis KZN R506] gi|289436888|gb|EFD19381.1| DNA gyrase subunit A gyrA [Mycobacterium tuberculosis KZN 605] Length=838 Score = 1678 bits (4346), Expect = 0.0, Method: Compositional matrix adjust. Identities = 833/838 (99%), Positives = 835/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGD SIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDVSIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKT RGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTSRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|31791183|ref|NP_853676.1| DNA gyrase subunit A [Mycobacterium bovis AF2122/97] gi|31616768|emb|CAD92868.1| DNA GYRASE (SUBUNIT A) GYRA (DNA TOPOISOMERASE (ATP-HYDROLYSING)) (DNA TOPOISOMERASE II) (TYPE II DNA TOPOISOMERASE) [Mycobacterium bovis AF2122/97] Length=838 Score = 1678 bits (4346), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/838 (99%), Positives = 836/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLT FDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTAFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|334265276|gb|AEG75289.1| DNA gyrase alpha subunit [Mycobacterium tuberculosis] Length=838 Score = 1677 bits (4343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 833/838 (99%), Positives = 835/838 (99%), Gaps = 0/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIY +LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYHTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKT RGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTSRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN Sbjct 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 >gi|336459821|gb|EGO38735.1| DNA gyrase, A subunit [Mycobacterium avium subsp. paratuberculosis S397] Length=839 Score = 1586 bits (4106), Expect = 0.0, Method: Compositional matrix adjust. Identities = 786/834 (95%), Positives = 813/834 (98%), Gaps = 1/834 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP D+ DR+EPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGGDAADRVEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNL ELA+AVFWAL+N++ADEE TLAAVM RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLGELAEAVFWALDNYEADEEATLAAVMERVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIVIE+KRDAVAKVV+NNLYKHTQLQTSFGANMLAIVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVIELKRDAVAKVVLNNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 QLIR+YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR Sbjct 361 QLIRHYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARQ 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDELAEIV++HGD RRTRI+AADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELAEIVEKHGDARRTRIVAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQIR Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDEL Sbjct 601 LAFQPEERIAQVIQIRSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TS Sbjct 721 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGA 833 GGGVIRTAA QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE+ D+ +++GA Sbjct 781 GGGVIRTAAGQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEEAADEAVDESDGA 834 >gi|183980041|ref|YP_001848332.1| DNA gyrase (subunit A) GyrA [Mycobacterium marinum M] gi|183173367|gb|ACC38477.1| DNA gyrase (subunit A) GyrA [Mycobacterium marinum M] Length=839 Score = 1584 bits (4101), Expect = 0.0, Method: Compositional matrix adjust. Identities = 777/839 (93%), Positives = 811/839 (97%), Gaps = 1/839 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP ++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGGEASDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRELA+AVFW LENHDADEE TLAAV RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLRELAEAVFWCLENHDADEEATLAAVTERVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 +DAYKTGRGSIRMRGVVE+EEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 ISDAYKTGRGSIRMRGVVEIEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+EIKRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVVEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV+HQLDVI+RRTTYRLRKANERAHILRGLVKALDALDEVIALIRAS+TVDIAR Sbjct 361 QMIRYYVEHQLDVIIRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIARV 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRI+DDLAKIEAEIADLEDILAKPERQR IV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIVDDLAKIEAEIADLEDILAKPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDELAEIVD+HGDDRRTRIIAADG+VSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELAEIVDKHGDDRRTRIIAADGEVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEA RTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEALRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQI+ Y DAPYLVLAT+NGLVKKSKLTDFDSNRSGGIVA+NLR DEL Sbjct 601 LAFQPEERIAQVIQIKSYEDAPYLVLATQNGLVKKSKLTDFDSNRSGGIVAINLRGEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ +DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DDRLLSLNVVRE Sbjct 661 VGAVLCSSEEDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDRLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVAT+GGYAKRT IEEYPVQGRGGKGVLT+MYDRRRGRLVGALIVDDDSELYA+TS Sbjct 721 GTYLLVATAGGYAKRTGIEEYPVQGRGGKGVLTIMYDRRRGRLVGALIVDDDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE+ D+ +A D++ N Sbjct 781 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEENADEAVAEATDTDESSN 839 >gi|41406104|ref|NP_958940.1| DNA gyrase subunit A [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394452|gb|AAS02323.1| GyrA [Mycobacterium avium subsp. paratuberculosis K-10] Length=839 Score = 1584 bits (4101), Expect = 0.0, Method: Compositional matrix adjust. Identities = 785/834 (95%), Positives = 812/834 (98%), Gaps = 1/834 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP D+ DR+EPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGGDAADRVEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNL ELA+AVFWAL+N++ADEE TLAAVM RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLGELAEAVFWALDNYEADEEATLAAVMERVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIVIE+KRDAVAKVV+NNLYKHTQLQTSFGANMLAIVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVIELKRDAVAKVVLNNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 QLIR+YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR Sbjct 361 QLIRHYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARQ 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDELAEIV++HGD RRTRI+AADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELAEIVEKHGDARRTRIVAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGL QDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLNQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQIR Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDEL Sbjct 601 LAFQPEERIAQVIQIRSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TS Sbjct 721 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGA 833 GGGVIRTAA QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE+ D+ +++GA Sbjct 781 GGGVIRTAAGQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEEAADEAVDESDGA 834 >gi|342862358|ref|ZP_08718999.1| DNA gyrase subunit A [Mycobacterium colombiense CECT 3035] gi|342130215|gb|EGT83543.1| DNA gyrase subunit A [Mycobacterium colombiense CECT 3035] Length=839 Score = 1576 bits (4082), Expect = 0.0, Method: Compositional matrix adjust. Identities = 778/837 (93%), Positives = 810/837 (97%), Gaps = 1/837 (0%) Query 1 MTDTTLPP-DDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP DDS+DRI+PVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGDDSVDRIQPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRELA+AV+W L+NH+ADEE TLAAV RVKGPDFPT GLIVGSQG Sbjct 181 GIAVGMATNIPPHNLRELAEAVYWCLDNHEADEEATLAAVCERVKGPDFPTHGLIVGSQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGSIRMRGVVEVEEDSRGRT+LVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IHDAYTTGRGSIRMRGVVEVEEDSRGRTALVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+EIKRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVVEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV HQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETV+IARA Sbjct 361 QMIRYYVAHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVEIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRI+DDLAKIEAEIADLEDILAKPERQR IV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIVDDLAKIEAEIADLEDILAKPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 DEL+EIVD+HGD+RRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 HDELSEIVDKHGDERRTRIIAADGDVADEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAYDLPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQI+ Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVAVNLRD DEL Sbjct 601 LAFQPEERIAQVIQIKSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAVNLRDGDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TS Sbjct 721 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQT 836 GGGVIRTAA QVRKAGRQTKGVRLMNLGE +TLLAIARNAEE+ D+ +++GA ++ Sbjct 781 GGGVIRTAAGQVRKAGRQTKGVRLMNLGEENTLLAIARNAEENADEVVEESDGAAES 837 >gi|118615925|ref|YP_904257.1| DNA gyrase subunit A [Mycobacterium ulcerans Agy99] gi|118568035|gb|ABL02786.1| DNA gyrase (subunit A) GyrA [Mycobacterium ulcerans Agy99] Length=839 Score = 1575 bits (4079), Expect = 0.0, Method: Compositional matrix adjust. Identities = 772/839 (93%), Positives = 807/839 (97%), Gaps = 1/839 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDT LPP ++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTMLPPGGEASDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPD SHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDHSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRELA+AVFW LENHDADEE TLAAV RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLRELAEAVFWCLENHDADEEATLAAVTDRVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 +DAYKTGRGSIRMRGVVE+EEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 ISDAYKTGRGSIRMRGVVEIEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+EIKRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVVEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV+HQLDV +RRTTYRLRKANERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QMIRYYVEHQLDVTIRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELL IDEIQAQAILDMQLRRLAALER+RI+DDLAKIEAEIADLEDILAKPERQR IV Sbjct 421 GLIELLGIDEIQAQAILDMQLRRLAALERERIVDDLAKIEAEIADLEDILAKPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDELAEIVD+HGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELAEIVDKHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEA RTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEALRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQI+ Y DAPYLVLAT+NG+VKKSKLTDFDSNRSGGIVA+NLR DEL Sbjct 601 LAFQPEERIAQVIQIKSYEDAPYLVLATQNGVVKKSKLTDFDSNRSGGIVAINLRGEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ +DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DDRLLSLNVVRE Sbjct 661 VGAVLCSSEEDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDRLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLL AT+GGYAKRT IEEYPVQGRGGKGVLT+MYDRRRGRLVGALIVDDDSELYA+TS Sbjct 721 GTYLLAATAGGYAKRTGIEEYPVQGRGGKGVLTIMYDRRRGRLVGALIVDDDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE+ D+ +A D++ N Sbjct 781 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEENADEAVAEATDTDESSN 839 >gi|206148715|gb|ACI05548.1| GyrA [Mycobacterium indicus pranii] Length=829 Score = 1569 bits (4063), Expect = 0.0, Method: Compositional matrix adjust. Identities = 775/826 (94%), Positives = 803/826 (98%), Gaps = 1/826 (0%) Query 1 MTDTTLPP-DDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP DDS+DRI+PVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGDDSVDRIQPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRELA+AV+W L+NH+ADEE TL AV RVKGPDFPT GLIVGSQG Sbjct 181 GIAVGMATNIPPHNLRELAEAVYWCLDNHEADEEATLTAVCERVKGPDFPTHGLIVGSQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IHDAYTTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+EIKRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVVEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR+YV HQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA Sbjct 361 QMIRHYVAHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQR IV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRRIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 DEL+EIVD+HGD+RRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 HDELSEIVDKHGDERRTRIIAADGDVNDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQIRGY DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDEL Sbjct 601 LAFQPEERIAQVIQIRGYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ +DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSSDEDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TS Sbjct 721 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDD 825 GGGVIRTAA QVRKAGRQTKGVRLMNLGE +TLLAIARNAE + D+ Sbjct 781 GGGVIRTAAGQVRKAGRQTKGVRLMNLGEENTLLAIARNAEANADE 826 >gi|118462773|ref|YP_879309.1| DNA gyrase subunit A [Mycobacterium avium 104] gi|118164060|gb|ABK64957.1| DNA gyrase, A subunit [Mycobacterium avium 104] Length=839 Score = 1568 bits (4060), Expect = 0.0, Method: Compositional matrix adjust. Identities = 777/816 (96%), Positives = 799/816 (98%), Gaps = 1/816 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP D+ DR+EPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGGDAADRVEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNL ELA+AVFWAL+N++ADEE TLAAVM RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLGELAEAVFWALDNYEADEEATLAAVMERVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIVIE+KRDAVAKVV+NNLYKHTQLQTSFGANMLAIVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVIELKRDAVAKVVLNNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 QLIR+YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR Sbjct 361 QLIRHYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARQ 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDELAEIV++HGD RRTRI+AADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELAEIVEKHGDARRTRIVAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQIR Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDEL Sbjct 601 LAFQPEERIAQVIQIRSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TS Sbjct 721 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAI 815 GGGVIRTAA QVRKAGRQTKGVRLMNLGEGDTLLAI Sbjct 781 GGGVIRTAAGQVRKAGRQTKGVRLMNLGEGDTLLAI 816 >gi|254773059|ref|ZP_05214575.1| DNA gyrase subunit A [Mycobacterium avium subsp. avium ATCC 25291] Length=839 Score = 1566 bits (4056), Expect = 0.0, Method: Compositional matrix adjust. Identities = 776/816 (96%), Positives = 799/816 (98%), Gaps = 1/816 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP D+ DR+EPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGGDAADRVEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLR+IDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLRQIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNL ELA+AVFWAL+N++ADEE TLAAVM RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLGELAEAVFWALDNYEADEEATLAAVMERVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIVIE+KRDAVAKVV+NNLYKHTQLQTSFGANMLAIVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVIELKRDAVAKVVLNNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 QLIR+YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR Sbjct 361 QLIRHYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARQ 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDELAEIV++HGD RRTRI+AADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELAEIVEKHGDARRTRIVAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQIR Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDEL Sbjct 601 LAFQPEERIAQVIQIRSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TS Sbjct 721 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAI 815 GGGVIRTAA QVRKAGRQTKGVRLMNLGEGDTLLAI Sbjct 781 GGGVIRTAAGQVRKAGRQTKGVRLMNLGEGDTLLAI 816 >gi|289441373|ref|ZP_06431117.1| DNA gyrase, A subunit [Mycobacterium tuberculosis T46] gi|289414292|gb|EFD11532.1| DNA gyrase, A subunit [Mycobacterium tuberculosis T46] Length=783 Score = 1541 bits (3989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 764/768 (99%), Positives = 766/768 (99%), Gaps = 0/768 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPDDSLDRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF Sbjct 1 MTDTTLPPDDSLDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG Sbjct 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT Sbjct 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS Sbjct 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ Sbjct 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 LIRYYVDHQLDVIVRRTTYRLRK NERAHILRGLVKALDALDEVIALIRASETVDIARAG Sbjct 361 LIRYYVDHQLDVIVRRTTYRLRKVNERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR Sbjct 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG Sbjct 661 GAVLCSADDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIV 768 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIV Sbjct 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIV 768 Score = 62.4 bits (150), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 55/202 (28%), Positives = 94/202 (47%), Gaps = 13/202 (6%) Query 623 LVLATRNGLVKKSKLTDFDSNRSGG--IVAVNLRDNDELVGAVLCSAGDDLLLVSANGQS 680 +V T G K++K + S + GG + L+ +D + +CS D +L + G+ Sbjct 517 VVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRV 576 Query 681 IRFSATD--EALRPMGRATSGVQGMRFNIDDRLLSLNVVR---EGTYLLVATSGGYAKRT 735 R A D EA R R + F ++R+ + +R + YL++AT G K++ Sbjct 577 YRAKAYDLPEASR-TARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKS 635 Query 736 AIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAA--RQVRK 793 + ++ GG + + R LVGA++ D +L V++ G IR +A +R Sbjct 636 KLTDFDSNRSGG---IVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDEALRP 692 Query 794 AGRQTKGVRLMNLGEGDTLLAI 815 GR T GV+ M D LL++ Sbjct 693 MGRATSGVQGMRFNIDDRLLSL 714 >gi|126432620|ref|YP_001068311.1| DNA gyrase subunit A [Mycobacterium sp. JLS] gi|126232420|gb|ABN95820.1| DNA gyrase subunit A [Mycobacterium sp. JLS] Length=836 Score = 1538 bits (3982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 756/832 (91%), Positives = 792/832 (96%), Gaps = 1/832 (0%) Query 1 MTDTTLPP-DDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP D++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGDEAGDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 FDSGFRPDR HAKSARSVAETMGNYHPHGD+SIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 FDSGFRPDRGHAKSARSVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRELADAV+W LEN +ADEE TLAAVM RVKGPDFPT GLIVGSQG Sbjct 181 GIAVGMATNIPPHNLRELADAVYWCLENFEADEETTLAAVMERVKGPDFPTHGLIVGSQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 D YKTGRGS++MRGVVE+EEDSRGRT +VITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IEDTYKTGRGSVKMRGVVEIEEDSRGRTGIVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+E+KRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV+HQLDVIVRRT YRLRKANERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QMIRYYVEHQLDVIVRRTRYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQAQAILDMQLRRLAALERQRI+DDLAKIEAEIADLEDILAKPERQR IV Sbjct 421 GLIELLDIDEIQAQAILDMQLRRLAALERQRIVDDLAKIEAEIADLEDILAKPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EI D++GDDRRTRI+ ADG+VSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELKEIADKYGDDRRTRIVPADGEVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVNHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP ERIAQVIQI+ Y DAPYLVLATRNGLVKKS+LTDFDSNRSGGIVAVNLRD DEL Sbjct 601 LAFQPNERIAQVIQIKSYEDAPYLVLATRNGLVKKSRLTDFDSNRSGGIVAVNLRDGDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ DDLLLVSA GQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVR Sbjct 661 VGAVLCSSEDDLLLVSAKGQSIRFSATDEALRPMGRATSGVQGMRFNADDELLSLNVVRP 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 TYLLVATSGGYAKRT+IEEY QGRGGKG+LT+ YDRRRG LVGALIVDDD+ELYA+TS Sbjct 721 DTYLLVATSGGYAKRTSIEEYTAQGRGGKGILTIQYDRRRGNLVGALIVDDDTELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDAN 831 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTL+AIARNAE + V+ + Sbjct 781 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLIAIARNAEAGDSTDEVNTD 832 >gi|118467811|ref|YP_884429.1| DNA gyrase subunit A [Mycobacterium smegmatis str. MC2 155] gi|1346234|sp|P48354.1|GYRA_MYCS2 RecName: Full=DNA gyrase subunit A gi|1122892|emb|CAA63918.1| DNA gyrase subunit A [Mycobacterium smegmatis str. MC2 155] gi|118169098|gb|ABK69994.1| DNA gyrase, A subunit [Mycobacterium smegmatis str. MC2 155] Length=842 Score = 1535 bits (3975), Expect = 0.0, Method: Compositional matrix adjust. Identities = 753/835 (91%), Positives = 797/835 (96%), Gaps = 1/835 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP+ ++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPEGEAHDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG Sbjct 121 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNL ELA+AV+W LEN++ADEE T AVM RVKGPDFPT+GLIVG+QG Sbjct 181 GIAVGMATNIPPHNLGELAEAVYWCLENYEADEEATCEAVMERVKGPDFPTSGLIVGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 D YKTGRGSI+MRGVVE+EEDSRGRTS+VITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 241 IEDTYKTGRGSIKMRGVVEIEEDSRGRTSIVITELPYQVNHDNFITSIAEQVRDGKLAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+E+KRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SNIEDQSSDRVGLRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 QLIR YVDHQLDVIVRRT YRLRKANERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QLIRLYVDHQLDVIVRRTRYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDID+IQAQAILDMQLRRLAALERQ+I+DDLAKIEAEIADLEDILAKPERQRGIV Sbjct 421 GLIELLDIDDIQAQAILDMQLRRLAALERQKIVDDLAKIEAEIADLEDILAKPERQRGIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EIVD+HGD RRTRI+ ADG+VSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELKEIVDKHGDARRTRIVPADGEVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDD+V HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDMVNHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQI+ Y DAPYLVLATRNGLVKKSKL+DFDSNRSGGIVA+NLR+ DEL Sbjct 601 LAFQPEERIAQVIQIKSYEDAPYLVLATRNGLVKKSKLSDFDSNRSGGIVAINLREGDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DDRLLSLNVVR Sbjct 661 VGAVLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNEDDRLLSLNVVRP 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 TYLLVATSGGYAKRT+I+EY VQGRGGKG+LT+ YDR+RG LVGALIVDDD+ELYA+TS Sbjct 721 DTYLLVATSGGYAKRTSIDEYSVQGRGGKGILTIQYDRKRGSLVGALIVDDDTELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGAD 834 GGVIRTAARQVRKAGRQTKGVRLMNL EGDTL+AIARNA+E ++ + AD Sbjct 781 TGGVIRTAARQVRKAGRQTKGVRLMNLAEGDTLIAIARNADEDEAAESISESDAD 835 >gi|169627127|ref|YP_001700776.1| DNA gyrase subunit A [Mycobacterium abscessus ATCC 19977] gi|169239094|emb|CAM60122.1| DNA gyrase (subunit A) GyrA (DNA topoisomerase) [Mycobacterium abscessus] Length=839 Score = 1526 bits (3950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 748/834 (90%), Positives = 795/834 (96%), Gaps = 2/834 (0%) Query 1 MTDTTLPP--DDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYA 58 MTDTTLPP DD++DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYA Sbjct 1 MTDTTLPPGGDDAVDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYA 60 Query 59 MFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGS 118 M+DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGS Sbjct 61 MYDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGS 120 Query 119 PGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGS 178 PGNDP AAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV EPTVLPSRFPNLLANGS Sbjct 121 PGNDPAAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVMEPTVLPSRFPNLLANGS 180 Query 179 GGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQ 238 GGIAVGMATN+PPHNLRELA+AV+WAL+NH+ADEE TL AV ++ GPDFPT+GLIVG+Q Sbjct 181 GGIAVGMATNMPPHNLRELAEAVYWALDNHEADEETTLKAVCEKITGPDFPTSGLIVGTQ 240 Query 239 GTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAG 298 G DAY TGRGSIRMRGV E+EEDS+GRTSLVITELPYQVNHDNFITSIAEQVRDGK+AG Sbjct 241 GIHDAYTTGRGSIRMRGVAEIEEDSKGRTSLVITELPYQVNHDNFITSIAEQVRDGKIAG 300 Query 299 ISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRL 358 ISNIEDQSSDRVGLRIV+ +KRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRL Sbjct 301 ISNIEDQSSDRVGLRIVVVLKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRL 360 Query 359 DQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR 418 DQLIR YV+HQLDVI+RRT YRLRKANERAHILRGLVKALDALDEVIALIRAS+TVDIAR Sbjct 361 DQLIRLYVNHQLDVIIRRTRYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIAR 420 Query 419 AGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGI 478 GLIELLD+DEIQAQAILDMQLRRLAALERQ+IIDDLAKIEAEIADLEDILAKPERQR I Sbjct 421 TGLIELLDVDEIQAQAILDMQLRRLAALERQKIIDDLAKIEAEIADLEDILAKPERQRAI 480 Query 479 VRDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQK 538 V+DELAEI +++GDDRRTRII+ADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQK Sbjct 481 VKDELAEITEKYGDDRRTRIISADGDVADEDLIAREDVVVTITETGYAKRTKTDLYRSQK 540 Query 539 RGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVAN 598 RGGKGVQGAGLKQDDIV HFFVCSTHD ILFFTT+GRVYRAKAYDLPEA+RTARGQHVAN Sbjct 541 RGGKGVQGAGLKQDDIVKHFFVCSTHDWILFFTTKGRVYRAKAYDLPEAARTARGQHVAN 600 Query 599 LLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDE 658 LLAFQPEERIAQVIQI+ Y DAPYLVLAT+NGLVKKSKLT+FDSNRSGG+VAVNLRD DE Sbjct 601 LLAFQPEERIAQVIQIKSYEDAPYLVLATKNGLVKKSKLTEFDSNRSGGLVAVNLRDGDE 660 Query 659 LVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVR 718 LVGAVLCSA DDLLLVSA+GQSIRFSATDEALRPMGRATSGVQGMRFN +D LLSLNVVR Sbjct 661 LVGAVLCSAEDDLLLVSAHGQSIRFSATDEALRPMGRATSGVQGMRFNGEDDLLSLNVVR 720 Query 719 EGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVT 778 EGTYLLVATSGGY+KRTAIEEYPVQGRGGKGVLTV YD RRG LVGAL+VD++SELYA+T Sbjct 721 EGTYLLVATSGGYSKRTAIEEYPVQGRGGKGVLTVQYDPRRGSLVGALVVDEESELYAIT 780 Query 779 SGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANG 832 SGGGVIRT A+QVRKAGRQTKGVRLMNLGEGDTLLAIA NA+E D DA G Sbjct 781 SGGGVIRTIAKQVRKAGRQTKGVRLMNLGEGDTLLAIAHNADEGDADPDEDAAG 834 >gi|1226022|emb|CAA58885.1| DNA gyrase [Mycobacterium smegmatis] Length=854 Score = 1498 bits (3877), Expect = 0.0, Method: Compositional matrix adjust. Identities = 739/817 (91%), Positives = 778/817 (96%), Gaps = 2/817 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP+ ++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPEGEAHDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DS DRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSA-SSDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 119 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGS Sbjct 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSR 179 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATN PPHNL ELA+AV+W LEN++ADEE T AVM RVKGPDFPT+GLIVG+QG Sbjct 180 GIAVGMATNNPPHNLGELAEAVYWCLENYEADEEATCEAVMERVKGPDFPTSGLIVGTQG 239 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 D YKTGRGSI+MRGVVE+EEDSRGRTS+VITELPYQVNHDNFITSIAEQVRDGKLAGI Sbjct 240 IEDTYKTGRGSIKMRGVVEIEEDSRGRTSIVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNIEDQSSDRVGLRIV+E+KRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLD Sbjct 300 SNIEDQSSDRVGLRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLD 359 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 QLIR YVDHQLDVIVRRT YRLRKANERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 360 QLIRLYVDHQLDVIVRRTRYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIARA 419 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDID+IQAQAILDMQLRRLAALERQ+I+DDLAKIEAEIADLEDILAKPERQRGIV Sbjct 420 GLIELLDIDDIQAQAILDMQLRRLAALERQKIVDDLAKIEAEIADLEDILAKPERQRGIV 479 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EIVD+HGD RRTRI+ ADG VSDEDLIAREDVVVTITETGYAKRTKTDLY SQKR Sbjct 480 RDELKEIVDKHGDARRTRIVPADGQVSDEDLIAREDVVVTITETGYAKRTKTDLYHSQKR 539 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDD+V HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANL Sbjct 540 GGKGVQGAGLKQDDMVNHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANL 599 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQI+ Y DAPYLVLATRNGLVKKSKL+DFDSNRSGGIVA+NLR+ DEL Sbjct 600 LAFQPEERIAQVIQIKSYEDAPYLVLATRNGLVKKSKLSDFDSNRSGGIVAINLREGDEL 659 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSAN QSIRFSATDEALRPMGRATSGVQGMRFN DDRLLSLNVVR Sbjct 660 VGAVLCSAEDDLLLVSANRQSIRFSATDEALRPMGRATSGVQGMRFNEDDRLLSLNVVRP 719 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 TYLLVATSGGYAKRT+I+EY VQGRGGKG+LT+ YDR+RG LVGALIVDDD+ELYA+TS Sbjct 720 DTYLLVATSGGYAKRTSIDEYSVQGRGGKGILTIQYDRKRGSLVGALIVDDDTELYAITS 779 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIA 816 GGVIRTAARQVRKAGRQTKGVRLMNL EGDTL+AIA Sbjct 780 TGGVIRTAARQVRKAGRQTKGVRLMNLAEGDTLIAIA 816 >gi|226303499|ref|YP_002763457.1| DNA gyrase subunit A [Rhodococcus erythropolis PR4] gi|226182614|dbj|BAH30718.1| DNA gyrase subunit A [Rhodococcus erythropolis PR4] Length=843 Score = 1443 bits (3735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 709/843 (85%), Positives = 773/843 (92%), Gaps = 7/843 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPPD DRIEPVDI+QEMQ SYIDYAMSVIVGRALP+VRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPDGPQHDRIEPVDIQQEMQNSYIDYAMSVIVGRALPDVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +D+G+RPDR + KSAR VAETMGNYHPHGD+SIYD+LVRMAQPWSLRYPLVDGQGNFGS Sbjct 61 YDNGYRPDRGYVKSARPVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLVDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTE RLTPLAMEMLREID ETVDF PNYDG+ QEPTVLPSR PNLL NGS Sbjct 121 GNDGAAAMRYTECRLTPLAMEMLREIDHETVDFTPNYDGKTQEPTVLPSRIPNLLINGSN 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A+A++WALEN +ADEE TLAAVM R+KGPDFPT GLIVG QG Sbjct 181 GIAVGMATNIPPHNLREVAEAIYWALENFEADEEATLAAVMERIKGPDFPTHGLIVGGQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGS+RMRGVVE+EED++GRT++VITELPYQVN DN ITSIAEQVRD K+ GI Sbjct 241 IQDAYTTGRGSVRMRGVVEIEEDAKGRTTIVITELPYQVNPDNLITSIAEQVRDAKIGGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S+I D+SSDRVG+RIV+ +KRDAVAKVV+NNLYKHTQLQTSFG NML+IVDGVPRTLRLD Sbjct 301 SDIHDESSDRVGMRIVVTVKRDAVAKVVLNNLYKHTQLQTSFGCNMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR Y HQL+VIVRRT Y LRKA ERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QMIRLYTTHQLEVIVRRTRYLLRKAQERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL+ELLD+DEIQA AIL MQLRRLAALERQ+I+D+LA+IE EIADLEDILA+PERQR IV Sbjct 421 GLMELLDVDEIQADAILGMQLRRLAALERQKIVDELAEIELEIADLEDILARPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EIVD++GDDRRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELKEIVDKYGDDRRTRIIAADGDVNDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV+HFFV STHD +LFFTT+GRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVSHFFVTSTHDWLLFFTTKGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP+ERI VIQI+ Y DAPYLVLATRNGLVKKSKLTDFDSNRSGGIVA+NLR DEL Sbjct 601 LAFQPDERIQSVIQIKTYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRGEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSA GQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSADDDLLLVSAQGQSIRFSATDEALRPMGRATSGVQGMRFNGDDELLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GT+LLVATSGGY+KRT +E+YPVQGRGGKGVLT+ YD++RG LVGALIVDDD ELYA+TS Sbjct 721 GTFLLVATSGGYSKRTGMEDYPVQGRGGKGVLTIQYDKKRGTLVGALIVDDDDELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGD------DNAVDANGA 833 GGGVIRTAA+QVRKAGRQTKGVRLMNLGEGDTLLAIARNA+E + DNA +A+GA Sbjct 781 GGGVIRTAAKQVRKAGRQTKGVRLMNLGEGDTLLAIARNADEPEELAAETTDNADNADGA 840 Query 834 DQT 836 ++ Sbjct 841 KES 843 >gi|229491128|ref|ZP_04384956.1| DNA gyrase, A subunit [Rhodococcus erythropolis SK121] gi|229321866|gb|EEN87659.1| DNA gyrase, A subunit [Rhodococcus erythropolis SK121] Length=843 Score = 1442 bits (3733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 709/843 (85%), Positives = 773/843 (92%), Gaps = 7/843 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPPD DRIEPVDI+QEMQ SYIDYAMSVIVGRALP+VRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPDGPQHDRIEPVDIQQEMQNSYIDYAMSVIVGRALPDVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +D+G+RPDR + KSAR VAETMGNYHPHGD+SIYD+LVRMAQPWSLRYPLVDGQGNFGS Sbjct 61 YDNGYRPDRGYVKSARPVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLVDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTE RLTPLAMEMLREID ETVDF PNYDG+ QEPTVLPSR PNLL NGS Sbjct 121 GNDGAAAMRYTECRLTPLAMEMLREIDHETVDFTPNYDGKTQEPTVLPSRIPNLLINGSN 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A+A++WALEN +ADEE TLAAVM R+KGPDFPT GLIVG QG Sbjct 181 GIAVGMATNIPPHNLREVAEAIYWALENFEADEEATLAAVMERIKGPDFPTHGLIVGGQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGS+RMRGVVE+EED++GRT++VITELPYQVN DN ITSIAEQVRD K+ GI Sbjct 241 IQDAYTTGRGSVRMRGVVEIEEDAKGRTTIVITELPYQVNPDNLITSIAEQVRDAKIGGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S+I D+SSDRVG+RIV+ +KRDAVAKVV+NNLYKHTQLQTSFG NML+IVDGVPRTLRLD Sbjct 301 SDIHDESSDRVGMRIVVTVKRDAVAKVVLNNLYKHTQLQTSFGCNMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR Y HQL+VIVRRT Y LRKA ERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QMIRLYTTHQLEVIVRRTRYLLRKAQERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL+ELLD+DEIQA AIL MQLRRLAALERQ+I+D+LA+IE EIADLEDILA+PERQR IV Sbjct 421 GLMELLDVDEIQADAILGMQLRRLAALERQKIVDELAEIELEIADLEDILARPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EIVD++GDDRRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELKEIVDKYGDDRRTRIIAADGDVNDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV+HFFV STHD +LFFTT+GRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVSHFFVTSTHDWLLFFTTKGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP+ERI VIQI+ Y DAPYLVLATRNGLVKKSKLTDFDSNRSGGIVA+NLR DEL Sbjct 601 LAFQPDERIQSVIQIKTYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRGEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCSA DDLLLVSA GQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSAEDDLLLVSAQGQSIRFSATDEALRPMGRATSGVQGMRFNGDDELLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GT+LLVATSGGY+KRT +E+YPVQGRGGKGVLT+ YD++RG LVGALIVDDD ELYA+TS Sbjct 721 GTFLLVATSGGYSKRTGMEDYPVQGRGGKGVLTIQYDKKRGTLVGALIVDDDDELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGD------DNAVDANGA 833 GGGVIRTAA+QVRKAGRQTKGVRLMNLGEGDTLLAIARNA+E + DNA +A+GA Sbjct 781 GGGVIRTAAKQVRKAGRQTKGVRLMNLGEGDTLLAIARNADEPEELAAETTDNADNADGA 840 Query 834 DQT 836 ++ Sbjct 841 KES 843 >gi|111020669|ref|YP_703641.1| DNA gyrase subunit A [Rhodococcus jostii RHA1] gi|110820199|gb|ABG95483.1| DNA topoisomerase subunit A [Rhodococcus jostii RHA1] Length=840 Score = 1434 bits (3713), Expect = 0.0, Method: Compositional matrix adjust. Identities = 707/830 (86%), Positives = 764/830 (93%), Gaps = 3/830 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP+ DRIEPVDI+QEMQ SYIDYAMSVIVGRALP+VRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPEGPGHDRIEPVDIQQEMQSSYIDYAMSVIVGRALPDVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +D+G+RPDR + KSAR VAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGS Sbjct 61 YDNGYRPDRGYVKSARPVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTE RLTPLAMEMLREID ETVDF PNYDGR QEP+VLPSR PNLL NGSG Sbjct 121 GNDGAAAMRYTECRLTPLAMEMLREIDHETVDFTPNYDGRTQEPSVLPSRIPNLLINGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A+A++WALEN +ADEE TL AVM RVKGPDFPT GLIVG QG Sbjct 181 GIAVGMATNIPPHNLREVAEAIYWALENWEADEESTLTAVMERVKGPDFPTHGLIVGGQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGS+RMRGVVE+EED++GRT++VITELPYQVN DN ITSIAEQVRD K+AGI Sbjct 241 IHDAYTTGRGSVRMRGVVEIEEDAKGRTTIVITELPYQVNPDNLITSIAEQVRDAKIAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S+I D+SSDR G+RIV+ +KRDAVAKVV+NNLYKHTQLQTSFG NML+IVDGVPRTLRLD Sbjct 301 SDIHDESSDRAGMRIVVTVKRDAVAKVVLNNLYKHTQLQTSFGCNMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR YV HQ++VI RRT Y LRKA ERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QMIRLYVAHQVEVIRRRTEYLLRKAEERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELL +DEIQA AIL MQLRRLAALERQ+IID+LA+IE EIADL+DIL KPERQR IV Sbjct 421 GLIELLTVDEIQADAILAMQLRRLAALERQKIIDELAEIEREIADLKDILEKPERQRRIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EIVD+HGDDRRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELKEIVDKHGDDRRTRIIAADGDVADEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV+HFFV STHD +LFFTT+GRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVSHFFVSSTHDWLLFFTTKGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP+ERI VIQI+ Y DAPYLVLATRNGLVKKSKLTDFDSNRSGGIVA+NLR DEL Sbjct 601 LAFQPDERIQSVIQIKTYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRGEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ DDLLLVSA GQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSSDDDLLLVSAQGQSIRFSATDEALRPMGRATSGVQGMRFNGDDELLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGY+KRT +E+YPVQGRGGKGVLT+ YD++RG LVGALIV+DD ELYA+TS Sbjct 721 GTYLLVATSGGYSKRTGMEDYPVQGRGGKGVLTIQYDKKRGTLVGALIVNDDDELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE--SGDDNA 827 GGGVIRTAA+QVRKAGRQTKGVRLMNLGEGDTLLAIARNA+E DDNA Sbjct 781 GGGVIRTAAKQVRKAGRQTKGVRLMNLGEGDTLLAIARNADEPDEPDDNA 830 >gi|226362909|ref|YP_002780689.1| DNA gyrase subunit A [Rhodococcus opacus B4] gi|226241396|dbj|BAH51744.1| DNA gyrase subunit A [Rhodococcus opacus B4] Length=840 Score = 1433 bits (3709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 706/830 (86%), Positives = 763/830 (92%), Gaps = 3/830 (0%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP+ DRIEPVDI+QEMQ SYIDYAMSVIVGRALP+VRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPEGPGHDRIEPVDIQQEMQSSYIDYAMSVIVGRALPDVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +D+G+RPDR + KSAR VAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGS Sbjct 61 YDNGYRPDRGYVKSARPVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTE RLTPLAMEMLREID ETVDF PNYDGR QEP+VLPSR PNLL NGSG Sbjct 121 GNDGAAAMRYTECRLTPLAMEMLREIDHETVDFTPNYDGRTQEPSVLPSRIPNLLINGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A+A++WALEN +ADEE TL AVM RVKGPDFPT GLIVG QG Sbjct 181 GIAVGMATNIPPHNLREVAEAIYWALENWEADEESTLTAVMERVKGPDFPTHGLIVGGQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGS+RMRGVVE+EED++GRT++VITELPYQVN DN ITSIAEQVRD K+AGI Sbjct 241 IHDAYTTGRGSVRMRGVVEIEEDAKGRTTIVITELPYQVNPDNLITSIAEQVRDAKIAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S+I D+SSDR G+RIV+ +KRDAVAKVV+NNLYKHTQLQTSFG NML+IVDGVPRTLRLD Sbjct 301 SDIHDESSDRAGMRIVVTVKRDAVAKVVLNNLYKHTQLQTSFGCNMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR YV HQ++VI RRT Y LRKA ERAHILRGLVKALDALDEVIALIRAS+TVDIARA Sbjct 361 QMIRLYVAHQVEVIRRRTEYLLRKAEERAHILRGLVKALDALDEVIALIRASQTVDIARA 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELL +DEIQA AIL MQLRRLAALERQ+IID+LA+IE EIADL+DIL KPERQR IV Sbjct 421 GLIELLTVDEIQADAILAMQLRRLAALERQKIIDELAEIEREIADLKDILEKPERQRRIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL EIVD+HGDDRRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 481 RDELKEIVDKHGDDRRTRIIAADGDVADEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV+HFFV STHD +LFFTT+GRVYRAKAY+LPEASRTARGQHVANL Sbjct 541 GGKGVQGAGLKQDDIVSHFFVSSTHDWLLFFTTKGRVYRAKAYELPEASRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP+ERI VIQI+ Y DAPYLVLATRNGLVKKSKLTDFDSNRSGGIVA+NLR DEL Sbjct 601 LAFQPDERIQSVIQIKTYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRGEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ DDLLLVSA GQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSSDDDLLLVSAQGQSIRFSATDEALRPMGRATSGVQGMRFNGDDELLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGY+KRT +E+YPVQGRGGKGVLT+ YD++RG LVGALIV+DD ELYA+TS Sbjct 721 GTYLLVATSGGYSKRTGMEDYPVQGRGGKGVLTIQYDKKRGTLVGALIVNDDDELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE--SGDDNA 827 GGGVIRTAA+QVRKAGRQTKGVRLMNLGEGD LLAIARNA+E DDNA Sbjct 781 GGGVIRTAAKQVRKAGRQTKGVRLMNLGEGDNLLAIARNADEPDETDDNA 830 >gi|54021971|ref|YP_116213.1| DNA gyrase subunit A [Nocardia farcinica IFM 10152] gi|54013479|dbj|BAD54849.1| putative DNA gyrase A subunit [Nocardia farcinica IFM 10152] Length=836 Score = 1432 bits (3707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 697/838 (84%), Positives = 770/838 (92%), Gaps = 5/838 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTD TLPP+ + DR+EPVDI+QEMQ SYIDYAMSVIVGRALPEVRDGLKPVHRR+LYAM+ Sbjct 1 MTDITLPPESAGDRVEPVDIQQEMQNSYIDYAMSVIVGRALPEVRDGLKPVHRRILYAMY 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 D+G+RPDR + KSAR V++TMGNYHPHGD++IYD+LVRMAQPW++RYPLVDGQGNFGS G Sbjct 61 DNGYRPDRGYVKSARPVSDTMGNYHPHGDSAIYDTLVRMAQPWAMRYPLVDGQGNFGSRG 120 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 ND AAMRYTE RLTPLAMEMLREID ETVDFIPNYDG+ QEP VLPSR PN+L NGS G Sbjct 121 NDGAAAMRYTECRLTPLAMEMLREIDHETVDFIPNYDGKTQEPVVLPSRVPNMLMNGSNG 180 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNL ELA+A++WAL+NHDADEE TLAA M R+KGPDFPTAGLIVG+QG Sbjct 181 IAVGMATNIPPHNLTELAEAIYWALDNHDADEETTLAACMERIKGPDFPTAGLIVGTQGI 240 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 DAY TGRGSI+MRGVVE+EED+RGRT++VITELPYQVN DNFI +IAEQV+DGK+AGI+ Sbjct 241 HDAYTTGRGSIKMRGVVEIEEDNRGRTTIVITELPYQVNTDNFINAIAEQVKDGKIAGIA 300 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 +I D+SSDRVGLRIV+ +KRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLDQ Sbjct 301 DIHDESSDRVGLRIVVTVKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQ 360 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 +IR YV+HQLDVI+RRT Y LRKA ERAHILRGLVKALDALDEVIALIR S D AR G Sbjct 361 MIRLYVNHQLDVIIRRTRYLLRKAEERAHILRGLVKALDALDEVIALIRRSANTDTARTG 420 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 L+ELLDIDEIQA AILDMQLRRL+ALERQ+IIDDLA+IEAEIAD +DIL KPERQR IVR Sbjct 421 LMELLDIDEIQATAILDMQLRRLSALERQKIIDDLARIEAEIADYKDILDKPERQRAIVR 480 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DELAEIV+++GD+RRT+I++ADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 481 DELAEIVEKYGDERRTQIVSADGDVADEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGAGLKQDDIV HFFV STHD +LFFT +GRVYRAKAY+LPEA+RTARGQHVANLL Sbjct 541 GKGVQGAGLKQDDIVKHFFVTSTHDWLLFFTNKGRVYRAKAYELPEANRTARGQHVANLL 600 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQP+E+IAQ+IQI+ Y DAPYLVLAT+NGLVKKS+L+DFDSNRSGGIVAVNLRDNDELV Sbjct 601 AFQPDEKIAQIIQIKTYEDAPYLVLATKNGLVKKSRLSDFDSNRSGGIVAVNLRDNDELV 660 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVLCSA DDLLLVSA GQSIRFSATDEALRPMGRATSGVQGMRFN +D LLSLNVVR G Sbjct 661 GAVLCSADDDLLLVSAQGQSIRFSATDEALRPMGRATSGVQGMRFNAEDELLSLNVVRPG 720 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 TYLLVATSGGYAKRTAIEEY QGRGGKGVLT+ +D RRG LVGALIVDDD ELYA+TSG Sbjct 721 TYLLVATSGGYAKRTAIEEYTAQGRGGKGVLTIQFDARRGTLVGALIVDDDDELYAITSG 780 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN 838 GGVIRTAA QVRKAGRQTKGVRLMNLGEGDTLLAIARNA+E +AVD G D TG+ Sbjct 781 GGVIRTAANQVRKAGRQTKGVRLMNLGEGDTLLAIARNADEP---DAVD--GGDDTGS 833 >gi|296137760|ref|YP_003645003.1| DNA gyrase subunit alpha [Tsukamurella paurometabola DSM 20162] gi|296025894|gb|ADG76664.1| DNA gyrase, A subunit [Tsukamurella paurometabola DSM 20162] Length=837 Score = 1418 bits (3671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 691/824 (84%), Positives = 761/824 (93%), Gaps = 3/824 (0%) Query 1 MTDTTLPPDDS--LDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYA 58 MTDTT PP ++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDG+KPV RR+LYA Sbjct 1 MTDTT-PPTETGGHDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGMKPVQRRILYA 59 Query 59 MFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGS 118 +D+G+RPDRS+ KSA+ VAETMGNYHPHGD++IYD+LVR+AQPWS+RYPL+DGQGNFGS Sbjct 60 SYDAGYRPDRSYVKSAKPVAETMGNYHPHGDSAIYDALVRLAQPWSMRYPLIDGQGNFGS 119 Query 119 PGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGS 178 PGNDP AAMRYTEARLTPLAMEMLR ID+ETVDF PNYDG+ QEPTVLP+R PNLL NGS Sbjct 120 PGNDPAAAMRYTEARLTPLAMEMLRGIDQETVDFAPNYDGKTQEPTVLPARVPNLLMNGS 179 Query 179 GGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQ 238 GGIAVGMATNIPPHNLRE+A+AVFW LEN+DAD E TL A M RVKGPDFPT GLIVG Q Sbjct 180 GGIAVGMATNIPPHNLREIAEAVFWCLENYDADSEATLEACMERVKGPDFPTHGLIVGGQ 239 Query 239 GTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAG 298 G DAY TGRGSIRMRGVVEVEEDS+G T LVITELPYQVN DN + SIAEQVRDGK+AG Sbjct 240 GIKDAYSTGRGSIRMRGVVEVEEDSKGATELVITELPYQVNPDNLVLSIAEQVRDGKIAG 299 Query 299 ISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRL 358 IS IEDQSSDRVG+RIV+ +KRDAVAKVV+NNLYKH+QLQTSFGANML+IVDGVPRTLRL Sbjct 300 ISKIEDQSSDRVGMRIVVRLKRDAVAKVVLNNLYKHSQLQTSFGANMLSIVDGVPRTLRL 359 Query 359 DQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR 418 DQ+IRYYV HQLDVIVRRT + LRKA ERAHILRGLVKALDALDEVIALIRAS+T +IAR Sbjct 360 DQMIRYYVAHQLDVIVRRTKFLLRKAEERAHILRGLVKALDALDEVIALIRASQTTEIAR 419 Query 419 AGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGI 478 GL+ELLD+DE+QA AILDMQLR+LAALERQ+IID+LA+IE EIADL+DIL KPERQR I Sbjct 420 TGLMELLDVDELQANAILDMQLRKLAALERQKIIDELAEIEREIADLKDILDKPERQRAI 479 Query 479 VRDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQK 538 VRDEL EIV++ GDDRRT+IIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQK Sbjct 480 VRDELGEIVEKFGDDRRTKIIAADGDVTDEDLIAREDVVVTITETGYAKRTKTDLYRSQK 539 Query 539 RGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVAN 598 RGGKGV+GA LKQDDIV HFFVCSTHD ILFFTT+GRVYRAKAY+LPE SRTARGQHVAN Sbjct 540 RGGKGVKGADLKQDDIVRHFFVCSTHDWILFFTTKGRVYRAKAYELPEQSRTARGQHVAN 599 Query 599 LLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDE 658 LLAFQPEERIAQVIQI+GY DAPYLVLAT+NGLVKKS+L DFDSNRSGGIVA+NLRD DE Sbjct 600 LLAFQPEERIAQVIQIKGYDDAPYLVLATKNGLVKKSRLEDFDSNRSGGIVAINLRDEDE 659 Query 659 LVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVR 718 LVGA L S+ DDLLLVS N QSIRFSATDEALRPMGRATSGVQGMRFN DD+LL+LNVV+ Sbjct 660 LVGAALVSSEDDLLLVSKNAQSIRFSATDEALRPMGRATSGVQGMRFNGDDQLLALNVVQ 719 Query 719 EGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVT 778 E TYLLVATSGGYAKRTA+++YPVQGRGGKGVLT+ +D +RG LVGALIV+D++ELYA+T Sbjct 720 EDTYLLVATSGGYAKRTAMDDYPVQGRGGKGVLTIQFDPKRGDLVGALIVNDETELYAIT 779 Query 779 SGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEES 822 SGGGVIRTAARQVRKAGRQTKGVRLMNLGEG TLLAIARNA+E+ Sbjct 780 SGGGVIRTAARQVRKAGRQTKGVRLMNLGEGTTLLAIARNADET 823 >gi|312137524|ref|YP_004004860.1| DNA gyrase subunit a [Rhodococcus equi 103S] gi|325677511|ref|ZP_08157175.1| DNA topoisomerase (ATP-hydrolyzing) subunit A [Rhodococcus equi ATCC 33707] gi|111185876|dbj|BAF02675.1| DNA gyrase subunit A [Rhodococcus equi] gi|311886863|emb|CBH46171.1| DNA gyrase subunit A [Rhodococcus equi 103S] gi|325551758|gb|EGD21456.1| DNA topoisomerase (ATP-hydrolyzing) subunit A [Rhodococcus equi ATCC 33707] Length=839 Score = 1417 bits (3669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 688/822 (84%), Positives = 762/822 (93%), Gaps = 1/822 (0%) Query 1 MTDTTLPPDD-SLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP++ S DRIEPVDI+QEMQ SYIDYAMSVIVGRALP+VRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPEEPSHDRIEPVDIQQEMQSSYIDYAMSVIVGRALPDVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +D+G+RPDR + KSAR VA+TMGNYHPHGD+SIYD+LVRMAQPWSLRYPLVDGQGNFGS Sbjct 61 YDNGYRPDRGYVKSARPVADTMGNYHPHGDSSIYDTLVRMAQPWSLRYPLVDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTE R+TPLAMEM+REID +TVDF+PNYDG+ QEPTVLPSR PNLL NGSG Sbjct 121 GNDGAAAMRYTECRMTPLAMEMVREIDHDTVDFVPNYDGKTQEPTVLPSRIPNLLVNGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A+A++WAL+NH+ADEE TL AVM RVKGPDFPT+GLIVG QG Sbjct 181 GIAVGMATNIPPHNLREVAEAIYWALDNHEADEEATLEAVMERVKGPDFPTSGLIVGGQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY+TGRGSIRMRGVVE+EE RG T +VITELPYQVN DN ITSIAEQVRDGK+AGI Sbjct 241 IQDAYRTGRGSIRMRGVVEIEESDRGSTQIVITELPYQVNPDNLITSIAEQVRDGKIAGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S IEDQSSDRVG+RIV+ IKRDAVAKVV+NNLYKH+QLQTSFGANML+IVDGVPRTLRLD Sbjct 301 SKIEDQSSDRVGMRIVVVIKRDAVAKVVLNNLYKHSQLQTSFGANMLSIVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV HQL+VI+RRT Y LRKA ERAHILRGLVKALDALDEVIALIR+S+TVD+AR Sbjct 361 QMIRYYVAHQLEVIIRRTRYLLRKAEERAHILRGLVKALDALDEVIALIRSSQTVDVART 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL++LL +DEIQA AIL MQLRRLAALERQ+IID+LA+IE EIADL+DIL KPERQR IV Sbjct 421 GLMDLLTVDEIQADAILAMQLRRLAALERQKIIDELAEIEREIADLKDILEKPERQRQIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 +DEL+EIV+++GDDRRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRT+TDLYRSQKR Sbjct 481 KDELSEIVEKYGDDRRTRIIAADGDVTDEDLIAREDVVVTITETGYAKRTRTDLYRSQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGV+GA LKQ+DIV +FFVCSTHD +LFFTT+GRVYRAKAY+LPEA+RTARGQHVANL Sbjct 541 GGKGVKGAELKQEDIVKNFFVCSTHDWLLFFTTKGRVYRAKAYELPEANRTARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP+E+I +I I+ Y DAPYLVLATRNGLVKKS+L DFDSNRSGGIVA+NLRD DEL Sbjct 601 LAFQPDEKIQSIIHIKSYEDAPYLVLATRNGLVKKSRLADFDSNRSGGIVAINLRDEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ DDLLLVSA GQSIRF+ATDEALRPMGRATSGVQGMRFN DD LLSLNVVRE Sbjct 661 VGAVLCSSDDDLLLVSAKGQSIRFAATDEALRPMGRATSGVQGMRFNQDDELLSLNVVRE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRT IE+Y QGRGGKGVLT+ YD +RG LVGA+IVDDD ELYA+TS Sbjct 721 GTYLLVATSGGYAKRTPIEDYVAQGRGGKGVLTIQYDPKRGTLVGAVIVDDDDELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEE 821 GGGVIRTAA+QVRKAGRQTKGVRLMNLGEGDTLLAIARNA+E Sbjct 781 GGGVIRTAAKQVRKAGRQTKGVRLMNLGEGDTLLAIARNADE 822 >gi|343928740|ref|ZP_08768185.1| DNA gyrase subunit A [Gordonia alkanivorans NBRC 16433] gi|343761489|dbj|GAA15111.1| DNA gyrase subunit A [Gordonia alkanivorans NBRC 16433] Length=829 Score = 1389 bits (3594), Expect = 0.0, Method: Compositional matrix adjust. Identities = 681/828 (83%), Positives = 747/828 (91%), Gaps = 2/828 (0%) Query 1 MTDTTLPPDDSL-DRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP D DRIEPVD+ QEMQ+SYIDYAMSVIVGRALPEVRDGLKPVHRR+LYA Sbjct 1 MTDTTLPPADGEGDRIEPVDLGQEMQKSYIDYAMSVIVGRALPEVRDGLKPVHRRLLYAS 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 FD+GFRPDRS+ KSA+ VAETMGNYHPHGD +IYD+LVR+AQPWS+RYPL+DGQGNFGS Sbjct 61 FDAGFRPDRSYVKSAKPVAETMGNYHPHGDTAIYDALVRLAQPWSMRYPLIDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTEARLTPLAMEMLR+I EETVDF PNYDG+ QEPTVLP+R PNLL NGSG Sbjct 121 GNDGAAAMRYTEARLTPLAMEMLRDIGEETVDFTPNYDGKTQEPTVLPARIPNLLINGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATN+PPHNL E+ADAVFWALE+HDAD+E TLAA M +KGPDFPTA LIVGSQG Sbjct 181 GIAVGMATNMPPHNLNEVADAVFWALEHHDADDETTLAACMECIKGPDFPTAALIVGSQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGSIRMR VV++EE+ +G T+LV+TELPYQVN DN I SIAEQV +GKL GI Sbjct 241 IKDAYTTGRGSIRMRSVVDIEEN-KGTTTLVVTELPYQVNPDNLIQSIAEQVNEGKLKGI 299 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S IEDQSSDRVG+RIV+ ++RDAVAKVV+NNLYKH+QLQTSFGANML+IVDGVPRTLRLD Sbjct 300 SRIEDQSSDRVGMRIVVTLRRDAVAKVVLNNLYKHSQLQTSFGANMLSIVDGVPRTLRLD 359 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV HQ+DVIVRRT YRLRKA ERAHILRGLVKALDALDEVIALIR S D AR Sbjct 360 QMIRYYVAHQIDVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRRSANTDTART 419 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GLIELLDIDEIQA AIL MQLRRL+ALERQ+I+D+LA+IE EIAD +DIL KPERQR IV Sbjct 420 GLIELLDIDEIQADAILAMQLRRLSALERQKIVDELAEIELEIADYKDILDKPERQRAIV 479 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL E+V+++GD RRT+IIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQ+R Sbjct 480 RDELKEVVEKYGDARRTKIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQRR 539 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFVCSTHD ILFFTT+GRVYRAKAY+LPEA+RTARGQHVANL Sbjct 540 GGKGVQGAGLKQDDIVKHFFVCSTHDWILFFTTKGRVYRAKAYELPEANRTARGQHVANL 599 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQ++ Y DAPYLVLATRNGLVKKSKL DFDSNRSGGI A+NLR DEL Sbjct 600 LAFQPEERIAQVIQLKTYEDAPYLVLATRNGLVKKSKLVDFDSNRSGGIAAINLRGEDEL 659 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGA LCS DDLLLVS GQSIRF A DE LRPMGR TSGVQGMRFN DD LLSLNVVRE Sbjct 660 VGAQLCSKDDDLLLVSQKGQSIRFHADDETLRPMGRQTSGVQGMRFNADDTLLSLNVVRE 719 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 TYLLVATSGGYAKRT +++YPVQGRGGKGVLT+ +DRRRG L+GALIVDDDSELYA+TS Sbjct 720 DTYLLVATSGGYAKRTGMDDYPVQGRGGKGVLTIAHDRRRGELIGALIVDDDSELYAITS 779 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNA 827 GGGVIRTAA+QVRKAGRQTKGVRLMNL EG T++AIARNA+E + +A Sbjct 780 GGGVIRTAAKQVRKAGRQTKGVRLMNLDEGTTVIAIARNADEPEETDA 827 >gi|262200052|ref|YP_003271260.1| DNA gyrase subunit A [Gordonia bronchialis DSM 43247] gi|262083399|gb|ACY19367.1| DNA gyrase, A subunit [Gordonia bronchialis DSM 43247] Length=827 Score = 1384 bits (3581), Expect = 0.0, Method: Compositional matrix adjust. Identities = 678/825 (83%), Positives = 748/825 (91%), Gaps = 2/825 (0%) Query 1 MTDTTLPPDDSL-DRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP DR+EPVD+ QEMQ+SYIDYAMSVIVGRALPEVRDGLKPVHRR+LYA Sbjct 1 MTDTTLPPAGGEGDRVEPVDLGQEMQKSYIDYAMSVIVGRALPEVRDGLKPVHRRLLYAS 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +D+GFRPDRS+ KSA+ VAETMGNYHPHGD +IYD+LVR+AQPWS+RYPL+DGQGNFGS Sbjct 61 YDAGFRPDRSYVKSAKPVAETMGNYHPHGDTAIYDALVRLAQPWSMRYPLIDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTEARLTPLAMEMLR+IDEETVDF PNYDG+ EPTVLP+R PNLL NGSG Sbjct 121 GNDGAAAMRYTEARLTPLAMEMLRDIDEETVDFTPNYDGKTNEPTVLPARIPNLLINGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+ADAV WALE+ DAD+E TLAA M +KGPDFPTA LIVGSQG Sbjct 181 GIAVGMATNIPPHNLREVADAVIWALEHPDADDETTLAACMEAIKGPDFPTAALIVGSQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGSIRMR VV++EE+ +G T+LV+TELPYQVN DN I SIAEQV +GKL GI Sbjct 241 IRDAYTTGRGSIRMRSVVDIEEN-KGTTTLVVTELPYQVNPDNLIQSIAEQVNEGKLKGI 299 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S IEDQSSDRVG+RIV+ ++RDAVAKVV+NNLYKH+QLQTSFGANML+IVDGVPRTLRLD Sbjct 300 SRIEDQSSDRVGMRIVVTLRRDAVAKVVLNNLYKHSQLQTSFGANMLSIVDGVPRTLRLD 359 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV HQ+DVIVRRT YRLRKA ERAHILRGLVKALDALDEVIALIRAS + AR Sbjct 360 QMIRYYVAHQIDVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASANTEAART 419 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL++LL+IDEIQA AIL MQLRRL+ALERQ+I+D+LA+IE EIADL+DILAKPERQR IV Sbjct 420 GLMDLLEIDEIQADAILAMQLRRLSALERQKIVDELAEIEREIADLQDILAKPERQRAIV 479 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL +VD++GDDRRT+IIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQ+R Sbjct 480 RDELKVVVDKYGDDRRTKIIAADGDVTDEDLIAREDVVVTITETGYAKRTKTDLYRSQRR 539 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIV HFFV STHD ILFFTT+GRVYRAKAY+LPEA+RTARGQHVANL Sbjct 540 GGKGVQGAGLKQDDIVKHFFVSSTHDWILFFTTKGRVYRAKAYELPEANRTARGQHVANL 599 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVIQ++ Y DAPYLVLATRNGLVKKSKL DFDSNRSGGI A+NLR DEL Sbjct 600 LAFQPEERIAQVIQLKSYQDAPYLVLATRNGLVKKSKLEDFDSNRSGGIAAINLRGEDEL 659 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGA LCSA DDLLLVS GQSIRF A DEALRPMGR TSGVQGMRFN DD LLSLNVVRE Sbjct 660 VGAQLCSADDDLLLVSQKGQSIRFHADDEALRPMGRQTSGVQGMRFNADDTLLSLNVVRE 719 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 GTYLLVATSGGYAKRT +++YPVQGRGGKGVLT+ +DRRRG L+GALIVDDDSELYA+TS Sbjct 720 GTYLLVATSGGYAKRTGMDDYPVQGRGGKGVLTIAHDRRRGELIGALIVDDDSELYAITS 779 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGD 824 GGGVIRTAA+QVRKAGRQTKGVRLMN+ EG T++AIARNA+E D Sbjct 780 GGGVIRTAAKQVRKAGRQTKGVRLMNIDEGTTVIAIARNADEPDD 824 >gi|333917685|ref|YP_004491266.1| DNA topoisomerase subunit A [Amycolicicoccus subflavus DQS3-9A1] gi|333479906|gb|AEF38466.1| DNA topoisomerase (ATP-hydrolyzing) subunit A [Amycolicicoccus subflavus DQS3-9A1] Length=848 Score = 1377 bits (3563), Expect = 0.0, Method: Compositional matrix adjust. Identities = 664/819 (82%), Positives = 744/819 (91%), Gaps = 1/819 (0%) Query 1 MTDTTLPPDDSL-DRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP+++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 17 MTDTTLPPEETPGDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 76 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 FD+GFRPDR + KS+R V E MGNYHPHGD SIYD++VR+AQPWS+RYPL+DGQGNFGSP Sbjct 77 FDAGFRPDRGYVKSSRVVGEVMGNYHPHGDTSIYDTMVRLAQPWSMRYPLIDGQGNFGSP 136 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDPPAAMRYTEARLTPLAMEMLR+I E+TVDF NYDG+ +EPTVLPSR PNLL NGSG Sbjct 137 GNDPPAAMRYTEARLTPLAMEMLRDIREDTVDFAANYDGKTREPTVLPSRIPNLLINGSG 196 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A A+FW LEN++ADEE TL A+ R+KGPDFPT+GLIVGS G Sbjct 197 GIAVGMATNIPPHNLREVAAAIFWCLENYEADEETTLIAMCERIKGPDFPTSGLIVGSDG 256 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 ++AY TGRGSIRMRGV E+EED+RGRT +VI ELPYQVN DN ITSIAEQVRD KL GI Sbjct 257 ISEAYSTGRGSIRMRGVTEIEEDNRGRTQIVIKELPYQVNPDNLITSIAEQVRDQKLTGI 316 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S I+D+SSDR+G+RIV+ +KRDAVAKVV+NNLYKHTQLQ SFG NML+IVDGVPRTLRLD Sbjct 317 SEIQDESSDRIGMRIVVTVKRDAVAKVVLNNLYKHTQLQNSFGVNMLSIVDGVPRTLRLD 376 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR YV HQLDVI+RRT +RL++A ERAHILRGLVKALDALDEVIALIR S+TVDIAR Sbjct 377 QMIRLYVAHQLDVIIRRTKFRLKQAEERAHILRGLVKALDALDEVIALIRRSQTVDIART 436 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL+ELLD+DEIQA AIL MQLRRLAALERQ+I+D+LA+IE EI DL+DILA+PERQR IV Sbjct 437 GLMELLDVDEIQADAILAMQLRRLAALERQKIVDELAEIEREIEDLKDILARPERQRQIV 496 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 DELAEIV+++GD+RRTRII +GDV+DEDLIAREDVVVTITETGYAKRTKTDLYR+Q+R Sbjct 497 HDELAEIVEKYGDERRTRIIQGEGDVADEDLIAREDVVVTITETGYAKRTKTDLYRAQRR 556 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDD+V HFFV STHD ILFFTT+GRVYR KAY+LPE SRTARGQHVANL Sbjct 557 GGKGVQGAGLKQDDMVRHFFVTSTHDWILFFTTKGRVYRVKAYELPEMSRTARGQHVANL 616 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP E+IAQ+I I+GY DAPYLVLATRNGLVKKS+L DFDSNRSGGIVA+NLR+NDEL Sbjct 617 LAFQPGEKIAQIIAIKGYQDAPYLVLATRNGLVKKSRLEDFDSNRSGGIVAINLRENDEL 676 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVLCS+ DDL+LVS GQ+IRF+ATDEALRPMGRATSGVQGMRFN DD LLSLNVV+E Sbjct 677 VGAVLCSSDDDLILVSGKGQAIRFAATDEALRPMGRATSGVQGMRFNTDDELLSLNVVQE 736 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 +LLVATSGGYAKRT ++EYPVQ RGGKGVLT+ +D RRG LVGA+IVD ELYA+TS Sbjct 737 TMFLLVATSGGYAKRTPLDEYPVQNRGGKGVLTIQFDARRGTLVGAIIVDMKDELYAITS 796 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARN 818 GGG+IRTAA QVRKAGRQTKGVRLMNLGEG LLAIARN Sbjct 797 GGGIIRTAASQVRKAGRQTKGVRLMNLGEGANLLAIARN 835 >gi|154795731|gb|ABS86853.1| gyrase A [Mycobacterium avium subsp. paratuberculosis] Length=726 Score = 1369 bits (3543), Expect = 0.0, Method: Compositional matrix adjust. Identities = 679/726 (94%), Positives = 697/726 (97%), Gaps = 0/726 (0%) Query 63 GFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGND 122 GFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPGND Sbjct 1 GFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGND 60 Query 123 PPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIA 182 PPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIA Sbjct 61 PPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIA 120 Query 183 VGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTAD 242 VGMATNIPPHNL ELA+AVFWAL+N++ADEE TLAAVM RVKGPDFPT+GLIVG+QG AD Sbjct 121 VGMATNIPPHNLGELAEAVFWALDNYEADEEATLAAVMERVKGPDFPTSGLIVGTQGIAD 180 Query 243 AYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNI 302 AYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNI Sbjct 181 AYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNI 240 Query 303 EDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLI 362 EDQSSDRVGLRIVIE+KRDAVAKVV+NNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLI Sbjct 241 EDQSSDRVGLRIVIELKRDAVAKVVLNNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLI 300 Query 363 RYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLI 422 R+YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR GLI Sbjct 301 RHYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARQGLI 360 Query 423 ELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDE 482 ELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDE Sbjct 361 ELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDE 420 Query 483 LAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGK 542 LAEIV++HGD RRTRI+AADGDVSDEDLIAREDV LYRSQKRGGK Sbjct 421 LAEIVEKHGDARRTRIVAADGDVSDEDLIAREDVXXXXXXXXXXXXXXXXLYRSQKRGGK 480 Query 543 GVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAF 602 GVQGAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANLLAF Sbjct 481 GVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAF 540 Query 603 QPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGA 662 QPEERIAQVIQIR Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDELVGA Sbjct 541 QPEERIAQVIQIRSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDELVGA 600 Query 663 VLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTY 722 VLCSA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVREGTY Sbjct 601 VLCSAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVREGTY 660 Query 723 LLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGG 782 LLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TSGGG Sbjct 661 LLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITSGGG 720 Query 783 VIRTAA 788 VIRTAA Sbjct 721 VIRTAA 726 >gi|296392547|ref|YP_003657431.1| DNA gyrase subunit A [Segniliparus rotundus DSM 44985] gi|296179694|gb|ADG96600.1| DNA gyrase, A subunit [Segniliparus rotundus DSM 44985] Length=826 Score = 1366 bits (3536), Expect = 0.0, Method: Compositional matrix adjust. Identities = 670/824 (82%), Positives = 744/824 (91%), Gaps = 1/824 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTD T P S DRIEPVD+ QEMQRS+IDYAMSVIV RALP+VRDGLKPVHRR+L+AM Sbjct 1 MTDPT-DPTPSRDRIEPVDLGQEMQRSFIDYAMSVIVSRALPDVRDGLKPVHRRILHAMQ 59 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 D GFRPDR + KSAR VAE MGNYHPHGD +IYD+LVRMAQPWSLRYPLVDGQGNFGS G Sbjct 60 DQGFRPDRGYVKSARPVAEAMGNYHPHGDTAIYDALVRMAQPWSLRYPLVDGQGNFGSRG 119 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 ND AAMRYTEARL PLAMEM+R+IDEETVDF+PNYDG+ +EP+VLP+R PNLL NGSGG Sbjct 120 NDGAAAMRYTEARLAPLAMEMVRDIDEETVDFVPNYDGKTEEPSVLPARIPNLLVNGSGG 179 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRE+ADA+FWALE+HDADE TL AV VKGPDFPTAGLIVG+ G Sbjct 180 IAVGMATNIPPHNLREVADAIFWALEHHDADEASTLEAVKEIVKGPDFPTAGLIVGTDGV 239 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 DAY TGRGSIRMRGVVEVEEDS+GR LVITELPYQVN DN ITSIAEQVRDGK+AGIS Sbjct 240 HDAYTTGRGSIRMRGVVEVEEDSQGRAILVITELPYQVNPDNMITSIAEQVRDGKIAGIS 299 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 I+D++SDR+G+RIV+ +KRDAVA+VV+NNLYKH+QLQT+FGANMLAIVDGVPRTLRLDQ Sbjct 300 AIDDETSDRIGMRIVVTLKRDAVARVVLNNLYKHSQLQTNFGANMLAIVDGVPRTLRLDQ 359 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 ++R Y+ HQ++VIVRRT YRLRKA ERAHILRGLVKALDALDEVIALIRAS+TVDIARAG Sbjct 360 ILRLYIAHQIEVIVRRTQYRLRKAEERAHILRGLVKALDALDEVIALIRASQTVDIARAG 419 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 L+ELLD+DEIQA AIL MQLRRLAALERQ+IID+LA+IE IAD +DILA+PERQR IVR Sbjct 420 LMELLDVDEIQADAILAMQLRRLAALERQKIIDELAEIEEAIADYQDILARPERQRAIVR 479 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 DEL EIVDRHGD+RRTRIIAA+G+V DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG Sbjct 480 DELKEIVDRHGDERRTRIIAAEGEVRDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 539 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGA LKQDDIVAHFFVCSTHD ILFFTT+GRVYR KAY+LPE SR ARGQHVANLL Sbjct 540 GKGVQGATLKQDDIVAHFFVCSTHDWILFFTTRGRVYRIKAYELPETSRAARGQHVANLL 599 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 A Q +E+IAQVI ++ Y D+PYLVLAT+ GL KKSKLT+FDSNRSGG++AVNLRD DELV Sbjct 600 ALQTDEKIAQVIHLQTYEDSPYLVLATKRGLTKKSKLTEFDSNRSGGLIAVNLRDEDELV 659 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GA LCS+ DDLLLVS +GQSIRF A DE LRPMGRATSGV GMRFN DD+LL++NVVR+G Sbjct 660 GAALCSSDDDLLLVSEHGQSIRFHANDEQLRPMGRATSGVLGMRFNEDDQLLAMNVVRDG 719 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 YLLVATSGGYAKRTA+ EYPVQGRGGKGVLTV YDRRRG LVGA+IVDDD+ELYA+T G Sbjct 720 AYLLVATSGGYAKRTALGEYPVQGRGGKGVLTVQYDRRRGGLVGAVIVDDDTELYAITQG 779 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGD 824 GGVIRT ARQVR+AGRQTKGVRLMNLGEGD L+A+ARN E+S + Sbjct 780 GGVIRTDARQVRRAGRQTKGVRLMNLGEGDRLIAVARNDEDSAE 823 >gi|326383915|ref|ZP_08205599.1| DNA gyrase subunit A [Gordonia neofelifaecis NRRL B-59395] gi|326197374|gb|EGD54564.1| DNA gyrase subunit A [Gordonia neofelifaecis NRRL B-59395] Length=832 Score = 1354 bits (3504), Expect = 0.0, Method: Compositional matrix adjust. Identities = 672/833 (81%), Positives = 741/833 (89%), Gaps = 3/833 (0%) Query 1 MTDTT-LPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 M+D T LP ++ DRIEPVD+ QEMQ SYIDYAMSVIVGRALPEVRDGLKPVHRR+LYA Sbjct 1 MSDETDLPENNGGDRIEPVDLGQEMQNSYIDYAMSVIVGRALPEVRDGLKPVHRRLLYAS 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 FD+GFRP+R + KSAR V+ETMGNYHPHGD+SIYD+LVR+AQPWS+RYPL+DGQGNFGS Sbjct 61 FDAGFRPERGYVKSARPVSETMGNYHPHGDSSIYDALVRLAQPWSMRYPLIDGQGNFGSR 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GND AAMRYTEARLTPLAMEMLR+I EETVDF+PNYDG+ QEPTVLPSR PNLL NGSG Sbjct 121 GNDGAAAMRYTEARLTPLAMEMLRDITEETVDFVPNYDGKTQEPTVLPSRIPNLLINGSG 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNL E+ADAVFWALEN +ADEE TLAA M VKGPDFPTA LIVGSQG Sbjct 181 GIAVGMATNIPPHNLNEVADAVFWALENPEADEETTLAACMEVVKGPDFPTAALIVGSQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY TGRGSIRMR VV++EE +G T L++TELPYQVN DN I+SIAEQV DGKL GI Sbjct 241 IRDAYMTGRGSIRMRSVVDIEE-VKGTTQLIVTELPYQVNPDNLISSIAEQVNDGKLKGI 299 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 S IEDQSSDR GLRIVI ++RD VA+VV+NNLYKH+QLQT+FGANML+IVDGVPRTLRLD Sbjct 300 SKIEDQSSDRAGLRIVITLRRDGVARVVLNNLYKHSQLQTNFGANMLSIVDGVPRTLRLD 359 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IRYYV HQ+DVI+RRT YRLRKA ERAHILRGLVKALDALDEVIALIRAS + AR Sbjct 360 QMIRYYVAHQIDVIIRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASANTEAART 419 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL++LLDIDEIQA AIL MQLRRL+ALERQ+IID+LA+IE EIADL+DIL +PERQR IV Sbjct 420 GLMDLLDIDEIQADAILAMQLRRLSALERQKIIDELAEIEREIADLKDILERPERQRAIV 479 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 RDEL E+VD++GDDRRTRII A+GDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKR Sbjct 480 RDELKEVVDKYGDDRRTRIIPAEGDVTDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGAGLKQDDIVAHFFV STHD +LFFTT+GRVYRAKAY+LPEA+RTARGQHVANL Sbjct 540 GGKGVQGAGLKQDDIVAHFFVSSTHDWLLFFTTKGRVYRAKAYELPEANRTARGQHVANL 599 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQPEERIAQVI+I GY DAPYLVLATRNGLVKKSKL FDSNRSGGI A+NLR +DEL Sbjct 600 LAFQPEERIAQVIRISGYEDAPYLVLATRNGLVKKSKLDAFDSNRSGGIAAINLRGDDEL 659 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGA LCSA DDLLLVS GQSIRF+A DE LRPMGR TSGVQGMRFN DD LLSL VVR Sbjct 660 VGARLCSADDDLLLVSKKGQSIRFTADDETLRPMGRQTSGVQGMRFNDDDELLSLTVVRP 719 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 T+LLVATSGGYAKRT IEEY QGRGGKGVLT+ +D +RG LVGAL+VD DSE+YA+TS Sbjct 720 DTFLLVATSGGYAKRTDIEEYSAQGRGGKGVLTIQHDPKRGDLVGALVVDIDSEIYAITS 779 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDN-AVDAN 831 GGGVIRT A+QVRKAGRQTKGVRLMNL +GD L+AIARNA+E +D A D N Sbjct 780 GGGVIRTKAKQVRKAGRQTKGVRLMNLSDGDNLIAIARNADEPDEDEGAADDN 832 >gi|154795735|gb|ABS86855.1| gyrase A [Mycobacterium avium subsp. paratuberculosis] Length=718 Score = 1348 bits (3489), Expect = 0.0, Method: Compositional matrix adjust. Identities = 668/718 (94%), Positives = 687/718 (96%), Gaps = 0/718 (0%) Query 66 PDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPA 125 PDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPGNDPPA Sbjct 1 PDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPA 60 Query 126 AMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGM 185 AMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGM Sbjct 61 AMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGM 120 Query 186 ATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAYK 245 ATNIPPHNL ELA+AVFWAL+N++ADEE TLAAVM RVKGPDFPT+GLIVG+QG ADAYK Sbjct 121 ATNIPPHNLGELAEAVFWALDNYEADEEATLAAVMERVKGPDFPTSGLIVGTQGIADAYK 180 Query 246 TGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQ 305 TGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIA+QVRDGKLAGISNIEDQ Sbjct 181 TGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAKQVRDGKLAGISNIEDQ 240 Query 306 SSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYY 365 SSDRVGLRIVIE+KRDAVAKVV+NNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIR+Y Sbjct 241 SSDRVGLRIVIELKRDAVAKVVLNNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRHY 300 Query 366 VDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELL 425 VDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIAR GLIELL Sbjct 301 VDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARQGLIELL 360 Query 426 DIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAE 485 DIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAE Sbjct 361 DIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAE 420 Query 486 IVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQ 545 IV++HGD RRTRI+AADGDVSDEDLIARED YRSQKRGGKGVQ Sbjct 421 IVEKHGDARRTRIVAADGDVSDEDLIAREDXXXXXXXXXXXXXXXXXXYRSQKRGGKGVQ 480 Query 546 GAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPE 605 GAGLKQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANLLAFQPE Sbjct 481 GAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPE 540 Query 606 ERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLC 665 ERIAQVIQIR Y DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDELVGAVLC Sbjct 541 ERIAQVIQIRSYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDELVGAVLC 600 Query 666 SAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLV 725 SA DDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVREGTYLLV Sbjct 601 SAEDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVREGTYLLV 660 Query 726 ATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGV 783 ATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TSGGGV Sbjct 661 ATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITSGGGV 718 >gi|240172097|ref|ZP_04750756.1| DNA gyrase subunit A [Mycobacterium kansasii ATCC 12478] Length=1257 Score = 1330 bits (3443), Expect = 0.0, Method: Compositional matrix adjust. Identities = 663/693 (96%), Positives = 682/693 (99%), Gaps = 0/693 (0%) Query 130 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 189 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI Sbjct 550 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 609 Query 190 PPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAYKTGRG 249 PPHNLRELADAVFWAL+N+DADEE TLAAVM RVKGPDFPTAGLIVGSQG ADAYKTGRG Sbjct 610 PPHNLRELADAVFWALDNYDADEETTLAAVMERVKGPDFPTAGLIVGSQGIADAYKTGRG 669 Query 250 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDR 309 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI+NIEDQ S+R Sbjct 670 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIANIEDQGSER 729 Query 310 VGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQ 369 VG+RIV+E+KRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLDQ+IRYYV+HQ Sbjct 730 VGVRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRYYVEHQ 789 Query 370 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE 429 LDVI+RRT YRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE Sbjct 790 LDVIIRRTRYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE 849 Query 430 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDR 489 IQAQAILDMQLRRLAALERQRI+DDLAKIEAEIADLEDILAKPERQRGIVRDEL EIVD+ Sbjct 850 IQAQAILDMQLRRLAALERQRIVDDLAKIEAEIADLEDILAKPERQRGIVRDELGEIVDK 909 Query 490 HGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL 549 HGDDRRTRI+AADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL Sbjct 910 HGDDRRTRIVAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL 969 Query 550 KQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIA 609 KQDDIVAHFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANLLAFQPEERIA Sbjct 970 KQDDIVAHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIA 1029 Query 610 QVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGD 669 QVIQIRGY DAPYLVLAT+NGLVKKSKLTDFDSNRSGGIVA+NLRDNDELVGAVLCSA D Sbjct 1030 QVIQIRGYEDAPYLVLATKNGLVKKSKLTDFDSNRSGGIVAINLRDNDELVGAVLCSAED 1089 Query 670 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSG 729 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DDRLLSLNVVREGTYLLVATSG Sbjct 1090 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDRLLSLNVVREGTYLLVATSG 1149 Query 730 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAAR 789 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALI DDDSELYA+TSGGGVIRTAAR Sbjct 1150 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIADDDSELYAITSGGGVIRTAAR 1209 Query 790 QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEES 822 QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEES Sbjct 1210 QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEES 1242 Score = 272 bits (696), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 123/130 (95%), Positives = 128/130 (99%), Gaps = 0/130 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MTDTTLPPD+S +RIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM+ Sbjct 1 MTDTTLPPDNSAERIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMY 60 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSPG Sbjct 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPG 120 Query 121 NDPPAAMRYT 130 NDPPAAMRY Sbjct 121 NDPPAAMRYC 130 >gi|317509460|ref|ZP_07967078.1| DNA gyrase, subunit A [Segniliparus rugosus ATCC BAA-974] gi|316252289|gb|EFV11741.1| DNA gyrase, subunit A [Segniliparus rugosus ATCC BAA-974] Length=826 Score = 1329 bits (3439), Expect = 0.0, Method: Compositional matrix adjust. Identities = 662/821 (81%), Positives = 739/821 (91%), Gaps = 4/821 (0%) Query 2 TDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFD 61 TDT+ PP D RIEPVD+ QEMQRS+IDYAMSVIV RALP+VRDGLKPVHRR+L+AM D Sbjct 5 TDTS-PPRD---RIEPVDLGQEMQRSFIDYAMSVIVSRALPDVRDGLKPVHRRILHAMQD 60 Query 62 SGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGN 121 GFRPDR + KSAR V+ETMGNYHPHGD++IYD+LVRMAQPWSLRYPL+DGQGNFGS GN Sbjct 61 QGFRPDRGYVKSARPVSETMGNYHPHGDSAIYDALVRMAQPWSLRYPLIDGQGNFGSRGN 120 Query 122 DPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGI 181 D AAMRYTEARL PLA+EM+R+ID ETVDF+PNYDG+ +EP+VLP+R PNLL NGSGGI Sbjct 121 DGAAAMRYTEARLAPLALEMVRDIDAETVDFVPNYDGKTEEPSVLPARIPNLLVNGSGGI 180 Query 182 AVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTA 241 AVGMATNIPPHNLRE+ADAVFWALE+HDADE TL AV VKGPDFPTAGLIVG+ G A Sbjct 181 AVGMATNIPPHNLREVADAVFWALEHHDADEATTLEAVKEIVKGPDFPTAGLIVGTDGIA 240 Query 242 DAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISN 301 DAY TGRGSIRMRGVVE+EEDS GRT LVITELPYQVN DN I +IAEQVRDGK+AGI+ Sbjct 241 DAYTTGRGSIRMRGVVEIEEDSGGRTILVITELPYQVNPDNMILAIAEQVRDGKIAGIAQ 300 Query 302 IEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQL 361 I+D+SSDR+G+RIV+ +KRDAVA+VV+NNLYKH+QLQT+FGANMLAIVDGVPRTLRLDQ+ Sbjct 301 IDDESSDRIGMRIVVTLKRDAVARVVLNNLYKHSQLQTNFGANMLAIVDGVPRTLRLDQI 360 Query 362 IRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGL 421 IR YV HQ++VIVRRT Y LRKA ERAHILRGLVKALDALDEVIALIRAS + D AR GL Sbjct 361 IRLYVAHQIEVIVRRTQYLLRKAEERAHILRGLVKALDALDEVIALIRASASADEARVGL 420 Query 422 IELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRD 481 +ELLD+DEIQA+AIL MQL RLAALERQ+I D+LA+IE EIAD +DILAKPERQR IVRD Sbjct 421 MELLDVDEIQARAILAMQLGRLAALERQKIFDELAEIEEEIADYKDILAKPERQRAIVRD 480 Query 482 ELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGG 541 EL EIVD+HGD+RRTRIIAA+GDV DEDLIA+EDVVVTITETGYAKRTKT+LYRSQKRGG Sbjct 481 ELKEIVDKHGDERRTRIIAAEGDVRDEDLIAQEDVVVTITETGYAKRTKTELYRSQKRGG 540 Query 542 KGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLA 601 KGVQGA LKQDDIVAHFFVCSTHD ILFFTT+GRVYR KAY+LP+ +R ARGQHVANLLA Sbjct 541 KGVQGAALKQDDIVAHFFVCSTHDWILFFTTRGRVYRIKAYELPDMNRAARGQHVANLLA 600 Query 602 FQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVG 661 Q EE+IAQVI +R Y DAPYLVLAT+ GL KKS+LT+FDSNRSGGIVAVNL+D+DELVG Sbjct 601 LQTEEKIAQVIHLRTYEDAPYLVLATKRGLTKKSRLTEFDSNRSGGIVAVNLKDDDELVG 660 Query 662 AVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGT 721 A LCSA DDLLLVS +GQSIRF A DE LRPMGRATSGV GMRFN DD+LL++NVVR+G Sbjct 661 AALCSADDDLLLVSEHGQSIRFHANDEQLRPMGRATSGVLGMRFNEDDQLLAMNVVRDGA 720 Query 722 YLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGG 781 YLLVATSGGYAKRT + EYP QGRGGKGVLTV YDRRRG LVGA+IVDDD+ELYA+TSGG Sbjct 721 YLLVATSGGYAKRTDLGEYPAQGRGGKGVLTVQYDRRRGGLVGAVIVDDDTELYAITSGG 780 Query 782 GVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEES 822 GVIRTAARQVR+AGRQTKGVRLMNL EGD L+A+ARN E+S Sbjct 781 GVIRTAARQVRRAGRQTKGVRLMNLAEGDRLIAVARNDEDS 821 >gi|331693905|ref|YP_004330144.1| DNA gyrase subunit A [Pseudonocardia dioxanivorans CB1190] gi|326948594|gb|AEA22291.1| DNA gyrase, A subunit [Pseudonocardia dioxanivorans CB1190] Length=839 Score = 1319 bits (3413), Expect = 0.0, Method: Compositional matrix adjust. Identities = 648/839 (78%), Positives = 735/839 (88%), Gaps = 6/839 (0%) Query 1 MTDT---TLPPDDSL---DRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRR 54 MTDT T+PP DRIEPVDI+QEMQRSYIDYAMSVIVGRALP V DGLKPVHRR Sbjct 1 MTDTLDPTVPPTGGAGGGDRIEPVDIQQEMQRSYIDYAMSVIVGRALPLVEDGLKPVHRR 60 Query 55 VLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQG 114 VLY+M ++GFRPDRS+ K AR V E MGNYHPHGD++IYD+LVR+AQPWS+RYPL+DGQG Sbjct 61 VLYSMGENGFRPDRSYVKCARVVGEVMGNYHPHGDSAIYDALVRLAQPWSMRYPLIDGQG 120 Query 115 NFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLL 174 NFGS GNDP AAMRYTE RL+PLAM ML++I+EETVDF+ NYDG+ QEP VLPSR PNLL Sbjct 121 NFGSRGNDPAAAMRYTECRLSPLAMAMLQDIEEETVDFLDNYDGKTQEPVVLPSRVPNLL 180 Query 175 ANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLI 234 NGS GIAVGMATNIPPHNLRE+ V WALENH+A +EE L A+M R+ GPDFPTAGLI Sbjct 181 INGSVGIAVGMATNIPPHNLREVGAGVVWALENHEASDEELLEALMARIPGPDFPTAGLI 240 Query 235 VGSQGTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDG 294 VG G AY+TGRGSIRMR VVEVEED++GRT LV+TELPYQVN DN I SIA VRDG Sbjct 241 VGRDGIESAYRTGRGSIRMRSVVEVEEDAKGRTILVVTELPYQVNPDNLIESIASMVRDG 300 Query 295 KLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPR 354 KL GI+ I D+SSDR+G+RIV +KRDAVAKVV+NNLYKHTQLQTSFG NMLAIVDGVPR Sbjct 301 KLTGIAEINDESSDRIGMRIVFTLKRDAVAKVVLNNLYKHTQLQTSFGVNMLAIVDGVPR 360 Query 355 TLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETV 414 TLRLDQ++R Y+ HQ++VIVRRT YRLRKA ERAHILRGLVKALDALDEVIALIRASETV Sbjct 361 TLRLDQVVRNYIRHQIEVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASETV 420 Query 415 DIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPER 474 D+AR GLI+LLD+D+IQAQAILDMQLRRLAALERQ+IID+LA+IE EIAD +DILA+PER Sbjct 421 DVARQGLIDLLDVDDIQAQAILDMQLRRLAALERQKIIDELAEIEREIADYQDILARPER 480 Query 475 QRGIVRDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLY 534 QR IVRDEL EIVD+HGD+RR+R++A DGDV++EDLIA EDVVVTITETGYAKRTKTDLY Sbjct 481 QRQIVRDELTEIVDKHGDERRSRLVADDGDVTNEDLIAVEDVVVTITETGYAKRTKTDLY 540 Query 535 RSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQ 594 R+QKRGGKGVQGA LKQDDIVAHFFVCSTHD +LFFT +GRVYR KAY+LPEA+R ARGQ Sbjct 541 RAQKRGGKGVQGATLKQDDIVAHFFVCSTHDWMLFFTNKGRVYRLKAYELPEANRNARGQ 600 Query 595 HVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLR 654 HVANLLA QP+E IAQV+QI+ Y APYLVLATR+GLVKKS+L DFDSNRSGG++ +NLR Sbjct 601 HVANLLALQPDEHIAQVMQIKDYQAAPYLVLATRSGLVKKSRLEDFDSNRSGGLIGINLR 660 Query 655 DNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSL 714 D DELVGAVLCSA DDLLLVSA GQSIRF+A D ALRPMGRATSGV GMRFN DRLLS+ Sbjct 661 DEDELVGAVLCSADDDLLLVSAEGQSIRFTADDAALRPMGRATSGVLGMRFNDGDRLLSI 720 Query 715 NVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSEL 774 VV++ ++LVAT+GGYAKRT IE+YPVQGRGGKGVLT+ YDRRRG LVGALIV D EL Sbjct 721 GVVQDDKFVLVATAGGYAKRTPIEDYPVQGRGGKGVLTLQYDRRRGTLVGALIVGIDDEL 780 Query 775 YAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGA 833 YA+TS GGVIRT+AR+VRKAGRQTKGVRLMNLG+ TL A+ARNAE+ DD+ ++ + + Sbjct 781 YAITSTGGVIRTSAREVRKAGRQTKGVRLMNLGDNATLQAVARNAEDDADDSELNGSSS 839 >gi|324999888|ref|ZP_08121000.1| DNA gyrase subunit A [Pseudonocardia sp. P1] Length=836 Score = 1309 bits (3388), Expect = 0.0, Method: Compositional matrix adjust. Identities = 638/812 (79%), Positives = 721/812 (89%), Gaps = 0/812 (0%) Query 14 RIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKS 73 R+EPVDI+QEMQRSYIDYAMSVIVGRALP V DGLKPVHRRVLY+M ++GFRPDRS K Sbjct 20 RVEPVDIQQEMQRSYIDYAMSVIVGRALPLVEDGLKPVHRRVLYSMGENGFRPDRSFVKC 79 Query 74 ARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEAR 133 AR V + MGNYHPHGD++IYD+LVR+AQPWS+RYPL+ GQGNFGS GNDP AAMRYTE R Sbjct 80 ARVVGDVMGNYHPHGDSAIYDALVRLAQPWSMRYPLITGQGNFGSRGNDPAAAMRYTECR 139 Query 134 LTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHN 193 L+PLAM ML++I+EETVDF+ NYDG+ QEP VLPSR PNLL NGS GIAVGMATNIPPHN Sbjct 140 LSPLAMAMLQDIEEETVDFLDNYDGKTQEPVVLPSRVPNLLINGSSGIAVGMATNIPPHN 199 Query 194 LRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRM 253 LRE+ V W LEN DA ++E L A+M R+KGPDFPT GLIVG G AY+TGRGSIRM Sbjct 200 LREVGAGVAWCLENPDATDDELLEALMERIKGPDFPTHGLIVGRDGIESAYRTGRGSIRM 259 Query 254 RGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLR 313 R VVEVE+D++GRT+LV+TELPY VN DN I SIA VRDGK+AGIS I D+SSDR+G+R Sbjct 260 RAVVEVEDDAKGRTTLVVTELPYMVNPDNLIESIATMVRDGKIAGISEIVDESSDRIGMR 319 Query 314 IVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVI 373 IV+ +KRDAVAKVV+NNLYKHTQLQ SFGANML+IVDGVPRTLRLDQ++R+YV HQ++VI Sbjct 320 IVVTLKRDAVAKVVLNNLYKHTQLQHSFGANMLSIVDGVPRTLRLDQIVRHYVRHQIEVI 379 Query 374 VRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQ 433 VRRT YRLRKA ERAHILRGLVKALDALDEVIALIRAS TVD+ARAGLI+LL +DEIQAQ Sbjct 380 VRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASATVDVARAGLIDLLTVDEIQAQ 439 Query 434 AILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDD 493 AILDMQLRRLAALERQ+I+D+LA+IE EIAD EDIL +PERQR IVRDELAEIV++HGDD Sbjct 440 AILDMQLRRLAALERQKIVDELAEIEREIADYEDILTRPERQREIVRDELAEIVEQHGDD 499 Query 494 RRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDD 553 RRTRI+ DGDV+DEDLIA EDVVVTIT TGYAKRTKTDLYR+QKRGGKGVQGA LKQDD Sbjct 500 RRTRIVGYDGDVTDEDLIAVEDVVVTITRTGYAKRTKTDLYRAQKRGGKGVQGAQLKQDD 559 Query 554 IVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQ 613 IV HFFVCSTHD +LFFT +GRVYR KAY+LPEA+RTARGQH+ANLLA QP+E IAQV+Q Sbjct 560 IVNHFFVCSTHDWMLFFTNRGRVYRLKAYELPEANRTARGQHLANLLALQPDEEIAQVMQ 619 Query 614 IRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLL 673 I+ Y PYLVLATRNGLVKKS+LTDFDSNR+GG++ +NLRD+DELVGAVLCS DDLLL Sbjct 620 IKDYQARPYLVLATRNGLVKKSRLTDFDSNRTGGLIGINLRDDDELVGAVLCSGDDDLLL 679 Query 674 VSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAK 733 VSA GQSIRF+ATD+ALRPMGRATSGV GMRFN D+LL+L V+R TYLLVAT+GGYAK Sbjct 680 VSAEGQSIRFTATDDALRPMGRATSGVLGMRFNSGDKLLALGVIRPDTYLLVATTGGYAK 739 Query 734 RTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRK 793 RT IE+YPVQGRGGKGVLT+ YDRRRG LVGALIV D ELYA+TS GGVIRT+AR+VRK Sbjct 740 RTPIEDYPVQGRGGKGVLTLQYDRRRGTLVGALIVGIDDELYAITSTGGVIRTSAREVRK 799 Query 794 AGRQTKGVRLMNLGEGDTLLAIARNAEESGDD 825 AGRQTKGVRLMNLGE TLLA+ARNAEE+ +D Sbjct 800 AGRQTKGVRLMNLGESSTLLAVARNAEETEED 831 >gi|300781944|ref|YP_003762235.1| DNA gyrase subunit A [Amycolatopsis mediterranei U32] gi|299791458|gb|ADJ41833.1| DNA gyrase subunit A [Amycolatopsis mediterranei U32] gi|340523297|gb|AEK38502.1| DNA gyrase subunit A [Amycolatopsis mediterranei S699] Length=845 Score = 1303 bits (3373), Expect = 0.0, Method: Compositional matrix adjust. Identities = 635/833 (77%), Positives = 724/833 (87%), Gaps = 0/833 (0%) Query 5 TLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGF 64 TLPP DRIEPVDI+QEMQRSYIDYAMSVIV RALP+VRDGLKPVHRRVLY+MFDSGF Sbjct 4 TLPPAPDHDRIEPVDIQQEMQRSYIDYAMSVIVSRALPDVRDGLKPVHRRVLYSMFDSGF 63 Query 65 RPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPP 124 RPDR + K +R V + MGNYHPHGD++IYD+LVR+AQPWS+RYPL+DGQGNFGSPGNDP Sbjct 64 RPDRGYNKCSRVVGDVMGNYHPHGDSAIYDALVRLAQPWSMRYPLIDGQGNFGSPGNDPA 123 Query 125 AAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVG 184 AAMRYTE+RL PLAM+ML +I+E+TVDF NYDGR QEP VLPSRFPNLL NG GIAVG Sbjct 124 AAMRYTESRLAPLAMQMLADIEEDTVDFSDNYDGRTQEPDVLPSRFPNLLVNGGSGIAVG 183 Query 185 MATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAY 244 MATNIPPHNLRE+++ V WALEN +A ++E LAA++ R+KGPDFPT +I+G+ G DAY Sbjct 184 MATNIPPHNLREVSEGVVWALENPEATDDELLAALLVRIKGPDFPTKAMILGTSGIEDAY 243 Query 245 KTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIED 304 +TGRGS+RMR VVEVEED++GRT LV++ELPYQVN DN + +IA VRDGKL GIS+I D Sbjct 244 RTGRGSVRMRAVVEVEEDAKGRTILVVSELPYQVNPDNLVENIANLVRDGKLTGISDIAD 303 Query 305 QSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRY 364 +S+ R G+RIV+ IKRDAVAKVV+NNL+KHTQLQ +FG NMLA+VDGVPRTLRLDQ+IR+ Sbjct 304 ESNSRSGMRIVVTIKRDAVAKVVLNNLFKHTQLQQNFGVNMLALVDGVPRTLRLDQIIRH 363 Query 365 YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIEL 424 YV HQ+DVIVRRT YRLRK ERAHILRGLVKALDALDEVIALIR S + D AR L+ L Sbjct 364 YVKHQMDVIVRRTRYRLRKKEERAHILRGLVKALDALDEVIALIRRSPSADEARPALMTL 423 Query 425 LDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELA 484 LDIDEIQA AILDMQLRRLAALERQRIID+LA+IE EIADL+DIL KPERQR I+RDEL Sbjct 424 LDIDEIQAVAILDMQLRRLAALERQRIIDELAEIEIEIADLKDILEKPERQRAIIRDELM 483 Query 485 EIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGV 544 IVD++GDDRRT+II GDV+DE+LIA EDVVVTIT TGYAKRTKTDLYRSQKRGGKGV Sbjct 484 AIVDKYGDDRRTKIIGFSGDVTDEELIAVEDVVVTITRTGYAKRTKTDLYRSQKRGGKGV 543 Query 545 QGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQP 604 QGA LKQDDIV HFFVCSTHD ILFFT +GRVYR KAY+LPEA+R ARGQHVANL+AFQP Sbjct 544 QGATLKQDDIVQHFFVCSTHDWILFFTNKGRVYRTKAYELPEANRNARGQHVANLMAFQP 603 Query 605 EERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVL 664 +E+IAQVIQI+ Y APYLVLAT+ GLVKK+KLTDFDSNRSGG++A+NLR+ DELVGAVL Sbjct 604 DEQIAQVIQIKNYEVAPYLVLATKRGLVKKTKLTDFDSNRSGGLIAINLREGDELVGAVL 663 Query 665 CSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLL 724 +A DDLLLVSA GQSIRF ATDEALRPMGR TSGV GMRFN D LL ++VV+EG +LL Sbjct 664 AAAEDDLLLVSAEGQSIRFHATDEALRPMGRPTSGVMGMRFNDGDELLGISVVKEGKFLL 723 Query 725 VATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVI 784 VAT GGY+KRTAIE+YPVQGRGGKGVLT+ +DR+RGRLVGALIVD + ELYA+TS GGVI Sbjct 724 VATDGGYSKRTAIEDYPVQGRGGKGVLTIQHDRKRGRLVGALIVDAEDELYAITSSGGVI 783 Query 785 RTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTG 837 RT A VRKAGRQTKGVRLMNLGEG TLLA+ARNA+E D +A A + G Sbjct 784 RTPAGDVRKAGRQTKGVRLMNLGEGTTLLAVARNADEPSDVANGEAPEAPEAG 836 >gi|296167138|ref|ZP_06849545.1| DNA topoisomerase (ATP-hydrolyzing) subunit A [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897460|gb|EFG77059.1| DNA topoisomerase (ATP-hydrolyzing) subunit A [Mycobacterium parascrofulaceum ATCC BAA-614] Length=1259 Score = 1302 bits (3370), Expect = 0.0, Method: Compositional matrix adjust. Identities = 651/707 (93%), Positives = 681/707 (97%), Gaps = 0/707 (0%) Query 130 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 189 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI Sbjct 551 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 610 Query 190 PPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAYKTGRG 249 PPHNLRELA+AV+W L+NH+ADEE TLAAV RVKGPDFPT GLIVGSQG DAY TGRG Sbjct 611 PPHNLRELAEAVYWCLDNHEADEEATLAAVCERVKGPDFPTHGLIVGSQGIHDAYTTGRG 670 Query 250 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDR 309 SIRMRGVVE+EEDSRGRTS+VITELPYQVNHDNFITSIAEQVRDG+L GI+NIEDQSSDR Sbjct 671 SIRMRGVVEIEEDSRGRTSIVITELPYQVNHDNFITSIAEQVRDGRLTGIANIEDQSSDR 730 Query 310 VGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQ 369 VGLRIV+EIKRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLDQ+IR+YV HQ Sbjct 731 VGLRIVVEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRHYVAHQ 790 Query 370 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE 429 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE Sbjct 791 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE 850 Query 430 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDR 489 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDEL EIVD+ Sbjct 851 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELTEIVDK 910 Query 490 HGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL 549 HGDDRRTRI+AADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL Sbjct 911 HGDDRRTRIVAADGDVNDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL 970 Query 550 KQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIA 609 KQDDIV HFFV STHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANLLAFQPEERIA Sbjct 971 KQDDIVRHFFVSSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIA 1030 Query 610 QVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGD 669 QVIQIRGY DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDELVGAVLCS+ + Sbjct 1031 QVIQIRGYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDELVGAVLCSSEE 1090 Query 670 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSG 729 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVREGTYLLVATSG Sbjct 1091 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNTDDYLLSLNVVREGTYLLVATSG 1150 Query 730 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAAR 789 GYAKRTAIEEYPVQGRGGKGVLTVM+DRRRG+LVGALIVDDDSELYA+TSGGGVIRT AR Sbjct 1151 GYAKRTAIEEYPVQGRGGKGVLTVMFDRRRGKLVGALIVDDDSELYAITSGGGVIRTDAR 1210 Query 790 QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQT 836 QVRKAGRQTKGVRLMNLGE +TLLAIARNAEE+ D+ +A GA ++ Sbjct 1211 QVRKAGRQTKGVRLMNLGEDNTLLAIARNAEENADEVVEEAEGAAES 1257 Score = 265 bits (678), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 131/163 (81%), Positives = 137/163 (85%), Gaps = 3/163 (1%) Query 1 MTDTTLPPD-DSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP ++ DRIEPVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGGEAGDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRY--TEARLTPLAMEMLREIDEETVDFIPNYDGRV 160 GNDPPAAMRY TE L L I + PN D V Sbjct 121 GNDPPAAMRYCLTEDALVRLPFGQSVRIGDIVPGASPNSDNEV 163 >gi|254820902|ref|ZP_05225903.1| DNA gyrase, A subunit [Mycobacterium intracellulare ATCC 13950] Length=1258 Score = 1300 bits (3363), Expect = 0.0, Method: Compositional matrix adjust. Identities = 651/695 (94%), Positives = 673/695 (97%), Gaps = 0/695 (0%) Query 130 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 189 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI Sbjct 551 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNI 610 Query 190 PPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAYKTGRG 249 PPHNLRELA+AV+W L+NH+ADEE TL AV RVKGPDFPT GLIVGSQG DAY TGRG Sbjct 611 PPHNLRELAEAVYWCLDNHEADEEATLTAVCERVKGPDFPTHGLIVGSQGIHDAYTTGRG 670 Query 250 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDR 309 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDR Sbjct 671 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDR 730 Query 310 VGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQ 369 VGLRIV+EIKRDAVAKVV+NNLYKHTQLQTSFGANML+IVDGVPRTLRLDQ+IR+YV HQ Sbjct 731 VGLRIVVEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRHYVAHQ 790 Query 370 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE 429 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE Sbjct 791 LDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDE 850 Query 430 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDR 489 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQR IV DEL+EIVD+ Sbjct 851 IQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRRIVHDELSEIVDK 910 Query 490 HGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL 549 HGD+RRTRIIAADGDV+DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL Sbjct 911 HGDERRTRIIAADGDVNDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGL 970 Query 550 KQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIA 609 KQDDIV HFFVCSTHD ILFFTTQGRVYRAKAY+LPEASRTARGQHVANLLAFQPEERIA Sbjct 971 KQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIA 1030 Query 610 QVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGD 669 QVIQIRGY DAPYLVLATRNGLVKK+KLTDFDSNRSGGIVA+NLRDNDELVGAVLCS+ + Sbjct 1031 QVIQIRGYEDAPYLVLATRNGLVKKTKLTDFDSNRSGGIVAINLRDNDELVGAVLCSSDE 1090 Query 670 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSG 729 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFN DD LLSLNVVREGTYLLVATSG Sbjct 1091 DLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDYLLSLNVVREGTYLLVATSG 1150 Query 730 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAAR 789 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVD+DSELYA+TSGGGVIRTAA Sbjct 1151 GYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDEDSELYAITSGGGVIRTAAG 1210 Query 790 QVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGD 824 QVRKAGRQTKGVRLMNLGE +TLLAIARNAE + D Sbjct 1211 QVRKAGRQTKGVRLMNLGEENTLLAIARNAEANAD 1245 Score = 271 bits (693), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 124/131 (95%), Positives = 129/131 (99%), Gaps = 1/131 (0%) Query 1 MTDTTLPP-DDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 MTDTTLPP DDS+DRI+PVDI+QEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM Sbjct 1 MTDTTLPPGDDSVDRIQPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 +DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYD+LVRMAQPWSLRYPLVDGQGNFGSP Sbjct 61 YDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSP 120 Query 120 GNDPPAAMRYT 130 GNDPPAAMRY Sbjct 121 GNDPPAAMRYC 131 >gi|256374167|ref|YP_003097827.1| DNA gyrase subunit A [Actinosynnema mirum DSM 43827] gi|255918470|gb|ACU33981.1| DNA gyrase, A subunit [Actinosynnema mirum DSM 43827] Length=840 Score = 1290 bits (3337), Expect = 0.0, Method: Compositional matrix adjust. Identities = 621/825 (76%), Positives = 721/825 (88%), Gaps = 1/825 (0%) Query 1 MTDTTLPP-DDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAM 59 M++TTLPP DR EP D++QEMQ SYIDYAMSVIVGRALP+VRDGLKPVH RVLY+M Sbjct 1 MSETTLPPIGGGSDRTEPRDLQQEMQNSYIDYAMSVIVGRALPDVRDGLKPVHVRVLYSM 60 Query 60 FDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP 119 FDS F P+RS+ K AR V + MGNYHPHGD++IYD+LVR+AQPW++RYPL+DGQGNFGS Sbjct 61 FDSRFLPERSYNKCARVVGDVMGNYHPHGDSAIYDALVRLAQPWAMRYPLIDGQGNFGSQ 120 Query 120 GNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSG 179 GNDP AAMRYTE RLTPLAM ML +I+E+TVDF NYDGR+QEPTVLPSR PNLL NGS Sbjct 121 GNDPAAAMRYTECRLTPLAMRMLADIEEDTVDFRDNYDGRIQEPTVLPSRVPNLLINGSS 180 Query 180 GIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG 239 GIAVGMATNIPPHNLRE+A+ V WAL+N +A +EETL A++ R+KGPDFPT G I+G+QG Sbjct 181 GIAVGMATNIPPHNLREVAEGVVWALDNPEASDEETLEAMIARIKGPDFPTYGQILGTQG 240 Query 240 TADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGI 299 DAY+TGRGS++MR VVE++ED++GRT LV++ELPYQVN DN + +IA VRD K+ GI Sbjct 241 IEDAYRTGRGSVKMRAVVEMDEDAKGRTILVVSELPYQVNPDNLVENIASLVRDQKINGI 300 Query 300 SNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLD 359 SNI D+S+ R G+RIV+ +KRDAVAKVV+NNLYKHTQLQ SFG NML++VDGVPRTLRLD Sbjct 301 SNIADESNRRSGMRIVVTVKRDAVAKVVLNNLYKHTQLQYSFGVNMLSLVDGVPRTLRLD 360 Query 360 QLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARA 419 Q+IR+YV HQ++VIVRRT +RLRKA ERAH+ RGLVKALD LD VIALIR S+T + AR+ Sbjct 361 QMIRHYVKHQIEVIVRRTKFRLRKAEERAHVWRGLVKALDQLDAVIALIRRSDTTESARS 420 Query 420 GLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIV 479 GL+ELL +DE+Q+ AIL+MQLRRLAALERQ+IID LA+IE +IADL+DILAKPERQR IV Sbjct 421 GLMELLSVDEVQSNAILEMQLRRLAALERQKIIDQLAEIELQIADLKDILAKPERQRAIV 480 Query 480 RDELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKR 539 R EL EIVD+HGDDRRT+I+ DGDVS EDLIA EDVVVTIT TGYAKRTKTDLYR+QKR Sbjct 481 RGELLEIVDKHGDDRRTKIVPFDGDVSMEDLIAVEDVVVTITRTGYAKRTKTDLYRAQKR 540 Query 540 GGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANL 599 GGKGVQGA LKQDDIV HFFVCSTHD ILFFT +GRVYR KAYDLPEASR ARGQHVANL Sbjct 541 GGKGVQGAQLKQDDIVQHFFVCSTHDWILFFTNKGRVYRTKAYDLPEASRNARGQHVANL 600 Query 600 LAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDEL 659 LAFQP+E IAQVIQI+ Y APYLVLATRNGLVKKSKL+DFDSNRSGG++ +NLR+ DEL Sbjct 601 LAFQPDEEIAQVIQIKNYEAAPYLVLATRNGLVKKSKLSDFDSNRSGGLIGINLREEDEL 660 Query 660 VGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVRE 719 VGAVL GDDLLLVS +GQSIRF ++D+ LRPMGRATSGVQGMRFN DD LLS+ VV+E Sbjct 661 VGAVLTGEGDDLLLVSKDGQSIRFHSSDDVLRPMGRATSGVQGMRFNSDDELLSMGVVQE 720 Query 720 GTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTS 779 G ++LVAT GGYAKRT IE+YPVQGRGGKGVLT+ +DRRRGRLVGALIVD + ELYA+TS Sbjct 721 GLFVLVATDGGYAKRTPIEDYPVQGRGGKGVLTIQHDRRRGRLVGALIVDVEDELYAITS 780 Query 780 GGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGD 824 GGVIRT+A+++RKAGRQTKGVRLMNLGE TL+A+ARNA+E D Sbjct 781 AGGVIRTSAKEIRKAGRQTKGVRLMNLGEKSTLIAVARNADEPAD 825 >gi|257054096|ref|YP_003131928.1| DNA gyrase subunit A [Saccharomonospora viridis DSM 43017] gi|256583968|gb|ACU95101.1| DNA gyrase subunit A [Saccharomonospora viridis DSM 43017] Length=841 Score = 1286 bits (3328), Expect = 0.0, Method: Compositional matrix adjust. Identities = 629/837 (76%), Positives = 724/837 (87%), Gaps = 5/837 (0%) Query 1 MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMF 60 MT+T LPP+ S R+EPVDI+QEMQ SYI+YAMSVIV RALP+VRDGLKPVHRRVLY+M+ Sbjct 1 MTET-LPPN-SRGRVEPVDIQQEMQNSYINYAMSVIVSRALPDVRDGLKPVHRRVLYSMY 58 Query 61 DSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPG 120 DSGFRPDR + K +R V + MGNYHPHGD++IYD+LVR+AQ WS+RYPL+DGQGNFGSPG Sbjct 59 DSGFRPDRGYNKCSRVVGDVMGNYHPHGDSAIYDALVRLAQRWSMRYPLIDGQGNFGSPG 118 Query 121 NDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGG 180 NDP AAMRYTEARL PLAMEMLR+I+E+TVDF NYDGR QEP VLPSR PNLL NG G Sbjct 119 NDPAAAMRYTEARLDPLAMEMLRDIEEDTVDFSDNYDGRTQEPDVLPSRIPNLLVNGGSG 178 Query 181 IAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGT 240 IAVGMATNIPPHNLRE+ D V WAL+N DADEEETLAA+M R+KGPDFPT+G I+G+QG Sbjct 179 IAVGMATNIPPHNLREVVDGVIWALDNPDADEEETLAALMQRIKGPDFPTSGQILGTQGI 238 Query 241 ADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGIS 300 ADAY+TGRGSIRMR VVEVEED++GRT+LV+TELPYQVN DN + +IA RDGK+AGI+ Sbjct 239 ADAYRTGRGSIRMRAVVEVEEDAKGRTTLVVTELPYQVNPDNLVENIASLARDGKIAGIA 298 Query 301 NIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQ 360 +I D+S+ R G+RIVI +KRDAVAKVV+NNLYKHTQLQ +FG NMLA+VDGVPRTLRLDQ Sbjct 299 DIADESNSRGGMRIVITLKRDAVAKVVLNNLYKHTQLQYNFGVNMLALVDGVPRTLRLDQ 358 Query 361 LIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAG 420 ++R+YV+HQ+DVIVRRT YRLRKA ERAH+LRGL KALD LD VI LIR S D AR G Sbjct 359 MVRHYVNHQIDVIVRRTRYRLRKAEERAHVLRGLAKALDHLDAVIELIRRSPNADEARTG 418 Query 421 LIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVR 480 L+ELLDIDE+QA AILDMQLR+LAALERQRI+D+LA++EA+IADL+D+L KPERQR IVR Sbjct 419 LMELLDIDEVQATAILDMQLRKLAALERQRILDELAELEAKIADLQDVLDKPERQREIVR 478 Query 481 DELAEIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRG 540 EL EI +++GDDRRT+II +GDVS EDLIA EDVVVTIT TGYAKRTKTDLYRSQKRG Sbjct 479 TELLEITEKYGDDRRTKIIPYEGDVSIEDLIAEEDVVVTITRTGYAKRTKTDLYRSQKRG 538 Query 541 GKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLL 600 GKGVQGA LKQDDIV HFFVCSTHD +LFFT +GRVYRAKAYDLPEA+R ARGQHVANLL Sbjct 539 GKGVQGATLKQDDIVEHFFVCSTHDWVLFFTNKGRVYRAKAYDLPEANRNARGQHVANLL 598 Query 601 AFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELV 660 AFQP+ERIA VIQI Y APYL+L T+ GLVKKS+L DFDS RSGG++ +NLR+ DELV Sbjct 599 AFQPDERIASVIQIPNYEVAPYLILGTKKGLVKKSRLADFDSPRSGGLIGINLREGDELV 658 Query 661 GAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREG 720 GAVL SA DDLLLVS++GQSIRF A DE LRPMGRATSGV GMRFN LLS+NV++ G Sbjct 659 GAVLASAEDDLLLVSSDGQSIRFHANDEVLRPMGRATSGVLGMRFNEGAELLSINVIKPG 718 Query 721 TYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSG 780 T+LLVAT GGYAKRTA+E+YPVQGRGGKGVLT+ +D +RGRLV ALIVD D ELYA+TS Sbjct 719 TFLLVATEGGYAKRTAVEDYPVQGRGGKGVLTIQHDEKRGRLVAALIVDADDELYAITSS 778 Query 781 GGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTG 837 GGVIRT A +VR+A RQTKGVRL+NLGEG+TLLA+ARNA+ D V A A+ TG Sbjct 779 GGVIRTPAAEVRRASRQTKGVRLINLGEGNTLLAVARNADRPSD---VSAEEAESTG 832 >gi|134096627|ref|YP_001102288.1| DNA gyrase subunit A [Saccharopolyspora erythraea NRRL 2338] gi|291005719|ref|ZP_06563692.1| DNA gyrase subunit A [Saccharopolyspora erythraea NRRL 2338] gi|133909250|emb|CAL99362.1| DNA gyrase subunit A [Saccharopolyspora erythraea NRRL 2338] Length=831 Score = 1284 bits (3322), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/814 (77%), Positives = 718/814 (89%), Gaps = 2/814 (0%) Query 5 TLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGF 64 TLPP+ RIEPVDI+QEMQ SYI+YAMSVIV RALP+VRDGLKPVHRRVLY+M+DSG+ Sbjct 4 TLPPEHG--RIEPVDIQQEMQNSYINYAMSVIVARALPDVRDGLKPVHRRVLYSMYDSGY 61 Query 65 RPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPP 124 RPDR + K +R V + MGNYHPHGD+SIYD+LVR+AQPWS+R+PL+DGQGNFGSPGNDP Sbjct 62 RPDRGYVKCSRVVGDVMGNYHPHGDSSIYDTLVRLAQPWSMRHPLIDGQGNFGSPGNDPA 121 Query 125 AAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVG 184 AAMRYTE+RL PLAM ML +I+E+TVDF NYDGR QEP VLP+R PNLL NG GGIAVG Sbjct 122 AAMRYTESRLDPLAMHMLADIEEDTVDFSDNYDGRSQEPDVLPARIPNLLVNGGGGIAVG 181 Query 185 MATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTADAY 244 MATNIPPHNLRE+AD V WALEN +AD+E L A++ R+KGPDFPT GLI+G+ ADAY Sbjct 182 MATNIPPHNLREVADGVVWALENPEADDEALLEALIERIKGPDFPTRGLIMGTNAIADAY 241 Query 245 KTGRGSIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIED 304 +TGRGSI+MR VV+VEED++GRTSLV+TELPYQVN DN I SIA R+GKL GIS+I D Sbjct 242 RTGRGSIKMRAVVDVEEDTKGRTSLVVTELPYQVNPDNLIESIAAMHREGKLTGISDIAD 301 Query 305 QSSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRY 364 +S+ R G+RIVI +KRD++ KVV+NNLYKHTQLQ +FG NMLA+V+GVPRTLRLDQ+IR+ Sbjct 302 ESNSRRGMRIVITLKRDSIPKVVLNNLYKHTQLQYTFGVNMLALVEGVPRTLRLDQVIRH 361 Query 365 YVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIEL 424 YV HQ++VIVRRT +RLRKA ERAHILRGLVKALD LDEVIALIR S TVD AR GLIEL Sbjct 362 YVKHQVEVIVRRTRFRLRKAEERAHILRGLVKALDMLDEVIALIRRSPTVDDARTGLIEL 421 Query 425 LDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELA 484 L++DE+QA AIL+MQLRRLAALERQ+I+D LA+IE EI DL+DIL KPERQR I+RDEL Sbjct 422 LEVDEVQANAILEMQLRRLAALERQKIVDQLAEIEREIEDLKDILDKPERQRQIIRDELM 481 Query 485 EIVDRHGDDRRTRIIAADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGV 544 IVD+HGDDRRTRI+ +G+VS EDLIA EDVVVT+T TGYAKRT+TDLYR+QKRGGKGV Sbjct 482 AIVDKHGDDRRTRIVPHEGEVSMEDLIADEDVVVTLTRTGYAKRTRTDLYRAQKRGGKGV 541 Query 545 QGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQP 604 QGA LKQDDIV+HFFVCSTHD ILFFT +GRVYRAKAY+LPEA+RTARGQHVANLLAFQP Sbjct 542 QGAQLKQDDIVSHFFVCSTHDWILFFTNKGRVYRAKAYELPEANRTARGQHVANLLAFQP 601 Query 605 EERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVL 664 +E IAQV+QI+ YT APYLVLATRNGLVKKS+LTDFDSNRSGG++ VNL+D+DELVGAVL Sbjct 602 DEHIAQVMQIKDYTAAPYLVLATRNGLVKKSRLTDFDSNRSGGLIGVNLKDDDELVGAVL 661 Query 665 CSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLL 724 CSA DDLLLVSA GQSIRF A+DEALRPMGRATSGV GMRFN D LL++ VVR Y+L Sbjct 662 CSADDDLLLVSAEGQSIRFHASDEALRPMGRATSGVLGMRFNEGDELLAMGVVRPDRYVL 721 Query 725 VATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVI 784 VAT GGYAKRT I++YPVQGRGGKGVLT+ YDR+RGRLVGALIVD D ELYA+TS GGVI Sbjct 722 VATDGGYAKRTPIDDYPVQGRGGKGVLTIQYDRKRGRLVGALIVDVDDELYAITSTGGVI 781 Query 785 RTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARN 818 RT A++VRKAGRQTKGVRLMNLG+G +++A+ARN Sbjct 782 RTTAKEVRKAGRQTKGVRLMNLGDGTSVVAVARN 815 Lambda K H 0.318 0.136 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 2046464323560 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40