BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0014c Length=626 Score E Sequences producing significant alignments: (Bits) Value gi|15607156|ref|NP_214528.1| transmembrane serine/threonine-prot... 1266 0.0 gi|289445539|ref|ZP_06435283.1| transmembrane serine/threonine-p... 1266 0.0 gi|254548946|ref|ZP_05139393.1| transmembrane serine/threonine-p... 1266 0.0 gi|289756073|ref|ZP_06515451.1| transmembrane serine/threonine-p... 1266 0.0 gi|308376287|ref|ZP_07668244.1| transmembrane serine/threonine-p... 1265 0.0 gi|289747784|ref|ZP_06507162.1| transmembrane serine/threonine-p... 1264 0.0 gi|240172114|ref|ZP_04750773.1| serine/threonine-protein kinase ... 1139 0.0 gi|183980051|ref|YP_001848342.1| serine/threonine-protein kinase... 1130 0.0 gi|118466937|ref|YP_879319.1| serine/threonine protein kinase [M... 1129 0.0 gi|294995627|ref|ZP_06801318.1| transmembrane serine/threonine-p... 1128 0.0 gi|254773068|ref|ZP_05214584.1| serine/threonine protein kinase ... 1127 0.0 gi|41406114|ref|NP_958950.1| PknB [Mycobacterium avium subsp. pa... 1127 0.0 gi|118615935|ref|YP_904267.1| serine/threonine-protein kinase B ... 1124 0.0 gi|342860265|ref|ZP_08716917.1| serine/threonine protein kinase ... 1123 0.0 gi|254821346|ref|ZP_05226347.1| serine/threonine protein kinase ... 1120 0.0 gi|296167117|ref|ZP_06849526.1| non-specific serine/threonine pr... 1117 0.0 gi|2344821|emb|CAA94718.1| serine-threonine protein kinase [Myco... 1093 0.0 gi|15826879|ref|NP_301142.1| serine/threonine protein kinase [My... 1092 0.0 gi|333988655|ref|YP_004521269.1| serine/threonine-protein kinase... 997 0.0 gi|145221406|ref|YP_001132084.1| protein kinase [Mycobacterium g... 951 0.0 gi|120401051|ref|YP_950880.1| protein kinase [Mycobacterium vanb... 947 0.0 gi|108796996|ref|YP_637193.1| serine/threonine protein kinase [M... 941 0.0 gi|126432628|ref|YP_001068319.1| serine/threonine protein kinase... 939 0.0 gi|118471844|ref|YP_884449.1| serine-threonine protein kinase [M... 849 0.0 gi|169627140|ref|YP_001700789.1| serine/threonine-protein kinase... 820 0.0 gi|298527412|ref|ZP_07014821.1| transmembrane serine/threonine-p... 753 0.0 gi|312137536|ref|YP_004004872.1| serine/threonine kinase pknb [R... 633 4e-179 gi|28948659|pdb|1MRU|A Chain A, Intracellular SerTHR PROTEIN KIN... 630 2e-178 gi|315113736|pdb|3ORM|A Chain A, Mycobacterium Tuberculosis Pknb... 627 2e-177 gi|315113730|pdb|3ORI|A Chain A, Mycobacterium Tuberculosis Pknb... 627 3e-177 gi|111020683|ref|YP_703655.1| serine/threonine protein kinase [R... 626 4e-177 gi|215794787|pdb|3F61|A Chain A, Crystal Structure Of M. Tubercu... 624 2e-176 gi|226362923|ref|YP_002780703.1| serine/threonine protein kinase... 624 2e-176 gi|215794788|pdb|3F69|A Chain A, Crystal Structure Of The Mycoba... 620 2e-175 gi|54022044|ref|YP_116286.1| putative serine/threonine protein k... 618 9e-175 gi|226303517|ref|YP_002763475.1| serine/threonine protein kinase... 618 1e-174 gi|229491116|ref|ZP_04384944.1| serine/threonine-protein kinase ... 616 3e-174 gi|28374107|pdb|1O6Y|A Chain A, Catalytic Domain Of Pknb Kinase ... 573 2e-161 gi|333917710|ref|YP_004491291.1| serine/threonine-protein kinase... 573 4e-161 gi|262200069|ref|YP_003271277.1| serine/threonine protein kinase... 567 2e-159 gi|343928761|ref|ZP_08768206.1| serine/threonine protein kinase ... 564 2e-158 gi|326383933|ref|ZP_08205617.1| serine/threonine protein kinase-... 560 3e-157 gi|331694005|ref|YP_004330244.1| serine/threonine protein kinase... 557 3e-156 gi|302531406|ref|ZP_07283748.1| serine/threonine protein kinase ... 548 1e-153 gi|294662208|pdb|2KUI|A Chain A, Nmr Structure Of The Pasta Doma... 548 2e-153 gi|134096662|ref|YP_001102323.1| serine/threonine protein kinase... 547 2e-153 gi|300781986|ref|YP_003762277.1| serine/threonine protein kinase... 547 2e-153 gi|296137777|ref|YP_003645020.1| serine/threonine protein kinase... 541 2e-151 gi|325000787|ref|ZP_08121899.1| serine/threonine protein kinase ... 540 2e-151 gi|317507736|ref|ZP_07965441.1| protein kinase [Segniliparus rug... 532 7e-149 >gi|15607156|ref|NP_214528.1| transmembrane serine/threonine-protein kinase B PKNB (protein kinase B) (STPK B) [Mycobacterium tuberculosis H37Rv] gi|15839388|ref|NP_334425.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|31791191|ref|NP_853684.1| transmembrane serine/threonine-protein kinase B PKNB (protein kinase B) (STPK B) [Mycobacterium bovis AF2122/97] 65 more sequence titles Length=626 Score = 1266 bits (3277), Expect = 0.0, Method: Compositional matrix adjust. Identities = 626/626 (100%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV Sbjct 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV Sbjct 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI Sbjct 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP Sbjct 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Sbjct 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 >gi|289445539|ref|ZP_06435283.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis CPHL_A] gi|289418497|gb|EFD15698.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis CPHL_A] Length=626 Score = 1266 bits (3276), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAV+LKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 241 EGLSADLDAVLLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV Sbjct 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV Sbjct 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI Sbjct 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP Sbjct 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Sbjct 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 >gi|254548946|ref|ZP_05139393.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=626 Score = 1266 bits (3276), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 625/626 (99%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV Sbjct 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV Sbjct 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSA Sbjct 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAT 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP Sbjct 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Sbjct 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 >gi|289756073|ref|ZP_06515451.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis EAS054] gi|289696660|gb|EFD64089.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis EAS054] Length=626 Score = 1266 bits (3275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV Sbjct 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV Sbjct 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFK+ANSPSTPELVGKVIGTNPPANQTSAI Sbjct 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKEANSPSTPELVGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP Sbjct 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Sbjct 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 >gi|308376287|ref|ZP_07668244.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis SUMu008] gi|308351605|gb|EFP40456.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis SUMu008] Length=660 Score = 1265 bits (3274), Expect = 0.0, Method: Compositional matrix adjust. Identities = 626/626 (100%), Positives = 626/626 (100%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 35 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 94 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 95 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 154 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 155 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 214 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 215 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 274 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 275 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 334 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV Sbjct 335 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 394 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV Sbjct 395 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 454 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI Sbjct 455 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 514 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP Sbjct 515 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 574 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Sbjct 575 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 634 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 635 NRVVYQNPPAGTGVNRDGIITLRFGQ 660 >gi|289747784|ref|ZP_06507162.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis 02_1987] gi|289760110|ref|ZP_06519488.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis T85] gi|289688312|gb|EFD55800.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis 02_1987] gi|289715674|gb|EFD79686.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis T85] gi|326905775|gb|EGE52708.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis W-148] gi|339293093|gb|AEJ45204.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis CCDC5079] gi|339296742|gb|AEJ48852.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis CCDC5180] Length=626 Score = 1264 bits (3270), Expect = 0.0, Method: Compositional matrix adjust. Identities = 625/626 (99%), Positives = 625/626 (99%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV Sbjct 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV Sbjct 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQREIPDVSTLTYAEAVKKLTAAGFG FKQANSPSTPELVGKVIGTNPPANQTSAI Sbjct 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGLFKQANSPSTPELVGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP Sbjct 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Sbjct 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 >gi|240172114|ref|ZP_04750773.1| serine/threonine-protein kinase B PknB [Mycobacterium kansasii ATCC 12478] Length=626 Score = 1139 bits (2945), Expect = 0.0, Method: Compositional matrix adjust. Identities = 564/626 (91%), Positives = 594/626 (95%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELG+ILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPRHLSDRYELGDILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET AGPLPYIVMEYVDGVTLRDIVHTEGPM PKRAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETSAGPLPYIVMEYVDGVTLRDIVHTEGPMPPKRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS+TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISSTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDPIPPS RH Sbjct 181 QYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPIPPSERH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVL+ AER SLL++ Sbjct 241 EGISADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLSGAERRSLLAAT 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 G+ +GPRTDPLPRQ LD TDRDR+ SVGRWVAVVAVLAVLT+ VTIAINTFGG TR V Sbjct 301 PGHPAGPRTDPLPRQVLDHTDRDRTTPSVGRWVAVVAVLAVLTIAVTIAINTFGGNTRKV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ+SADAIA LQNRGFK RTLQKPDSTIPPDHVIGTDP ANTSV AG +IT+NV Sbjct 361 QVPDVRGQASADAIAALQNRGFKTRTLQKPDSTIPPDHVIGTDPGANTSVGAGADITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+LTYAEAVKKLTAAGF +FKQA SPS+PE+ GKVIGTNPPANQTSAI Sbjct 421 STGPEQRELPDVSSLTYAEAVKKLTAAGFSKFKQAASPSSPEMAGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ IIVGSGP K IPDVAGQTVD+AQKNLNVYGFTKFSQA VDSP+PAG+V GTNPP Sbjct 481 TNVITIIVGSGPEAKQIPDVAGQTVDLAQKNLNVYGFTKFSQAQVDSPKPAGDVVGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVPVDSVIELQVS+GNQFVMPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGGSQH Sbjct 541 AGTTVPVDSVIELQVSRGNQFVMPDLSGMFWTDAEPRLRALGWTGVLDKGPDVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQ+PPAG+GVNRDGIITL+FGQ Sbjct 601 NRVVYQSPPAGSGVNRDGIITLKFGQ 626 >gi|183980051|ref|YP_001848342.1| serine/threonine-protein kinase B PknB [Mycobacterium marinum M] gi|183173377|gb|ACC38487.1| serine/threonine-protein kinase B PknB [Mycobacterium marinum M] Length=626 Score = 1130 bits (2922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 560/626 (90%), Positives = 594/626 (95%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELG+ILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGDILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETP+GPLPYIVMEYV+GVTLRDIVHT+GPM P RAIE+IA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPSGPLPYIVMEYVNGVTLRDIVHTDGPMAPTRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDPIPPS RH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPIPPSERH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SA+LDAVVLKALAKNP+NRYQTAAEMRADLVRVHNGE PEAPKVLT AER SL +S+ Sbjct 241 EGISAELDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGESPEAPKVLTGAERRSLTASS 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 + + PRTDPLPRQ LDDTDRDRS SVGRWVAVVAVLAVLT+VVTIAINTFGG TR+V Sbjct 301 PSSPAAPRTDPLPRQTLDDTDRDRSTPSVGRWVAVVAVLAVLTIVVTIAINTFGGNTRNV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVP+VRGQ+SADAIA LQNRGFK RTL KPDSTIPPDHVIGTDPAAN SVSAGD+IT+NV Sbjct 361 QVPNVRGQASADAIAALQNRGFKTRTLLKPDSTIPPDHVIGTDPAANASVSAGDQITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS++TYAEAVKKLTAAGFGRFK+A SPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQRELPDVSSMTYAEAVKKLTAAGFGRFKEAKSPSTPELMGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ IIVGSGPATK IPDVAGQ+V+ A++NLNVYGFTKFSQASVDSP+PAG V TNPP Sbjct 481 TNVITIIVGSGPATKQIPDVAGQSVEEAEQNLNVYGFTKFSQASVDSPKPAGSVIATNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVP+DSVIELQVSKGNQFVMPDLSGMFW DAEPRLRALGWTG LDKG DVDAGGSQH Sbjct 541 AGTTVPIDSVIELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGSLDKGPDVDAGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAG GVNRDGI+TL+FGQ Sbjct 601 NRVVYQNPPAGAGVNRDGIVTLKFGQ 626 >gi|118466937|ref|YP_879319.1| serine/threonine protein kinase [Mycobacterium avium 104] gi|118168224|gb|ABK69121.1| serine/threonine protein kinase [Mycobacterium avium 104] gi|336462091|gb|EGO40933.1| hypothetical protein MAPs_24240 [Mycobacterium avium subsp. paratuberculosis S397] Length=626 Score = 1129 bits (2919), Expect = 0.0, Method: Compositional matrix adjust. Identities = 542/626 (87%), Positives = 581/626 (93%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAETP+GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPSIVAVYDTGEAETPSGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SADLDAVVLKALAKNP+NRYQTAAEMRADLVRVHNGE PEAPKVLTDAER+SLLSS Sbjct 241 EGISADLDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGEKPEAPKVLTDAERSSLLSSG 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AG RTDPLPRQ L D+ DR++GSVGRW+ VA LAVLT++V IA NTFGG RDV Sbjct 301 AGAAGPSRTDPLPRQVLADSGEDRTVGSVGRWIVAVAALAVLTIIVVIAFNTFGGGARDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAIA LQNRGFK RTLQKPDS IPPDHVIGTDP AN SVSAGDEIT+NV Sbjct 361 QVPDVRGQVSADAIAALQNRGFKTRTLQKPDSAIPPDHVIGTDPGANASVSAGDEITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L+Y++AV KL AAGF +FKQANSPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQREVPDVSSLSYSDAVTKLKAAGFSKFKQANSPSTPELLGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ +IVGSGP TK +PD+AGQTVD+AQKNL VYGFTK +Q VDSPRPAGEV GTNPP Sbjct 481 TNVITLIVGSGPETKQVPDIAGQTVDIAQKNLTVYGFTKITQVQVDSPRPAGEVIGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G TVPVDSVIELQVSKGNQF+MPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGG+Q Sbjct 541 KGQTVPVDSVIELQVSKGNQFIMPDLSGMFWTDAEPRLRALGWTGILDKGPDVDAGGAQS 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 +RVVYQNPPAG GVNRDGIITL+FGQ Sbjct 601 HRVVYQNPPAGAGVNRDGIITLKFGQ 626 >gi|294995627|ref|ZP_06801318.1| transmembrane serine/threonine-protein kinase B pknB [Mycobacterium tuberculosis 210] Length=561 Score = 1128 bits (2918), Expect = 0.0, Method: Compositional matrix adjust. Identities = 559/561 (99%), Positives = 560/561 (99%), Gaps = 0/561 (0%) Query 66 LNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADACQA 125 +NHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADACQA Sbjct 1 MNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADACQA 60 Query 126 LNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSP 185 LNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSP Sbjct 61 LNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSP 120 Query 186 EQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSA 245 EQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSA Sbjct 121 EQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSA 180 Query 246 DLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLS 305 DLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLS Sbjct 181 DLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLS 240 Query 306 GPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDV 365 GPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDV Sbjct 241 GPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDV 300 Query 366 RGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPE 425 RGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPE Sbjct 301 RGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPE 360 Query 426 QREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAITNVVI 485 QREIPDVSTLTYAEAVKKLTAAGFG FKQANSPSTPELVGKVIGTNPPANQTSAITNVVI Sbjct 361 QREIPDVSTLTYAEAVKKLTAAGFGLFKQANSPSTPELVGKVIGTNPPANQTSAITNVVI 420 Query 486 IIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTV 545 IIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTV Sbjct 421 IIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTV 480 Query 546 PVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVY 605 PVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVY Sbjct 481 PVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVY 540 Query 606 QNPPAGTGVNRDGIITLRFGQ 626 QNPPAGTGVNRDGIITLRFGQ Sbjct 541 QNPPAGTGVNRDGIITLRFGQ 561 >gi|254773068|ref|ZP_05214584.1| serine/threonine protein kinase [Mycobacterium avium subsp. avium ATCC 25291] Length=626 Score = 1127 bits (2914), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/626 (87%), Positives = 580/626 (93%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAETP+GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPSIVAVYDTGEAETPSGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SADLDAVVLKALAKNP+NRYQTAAEMRADLVRVHNGE PEAPKVLTDAER+SLLSS Sbjct 241 EGISADLDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGEKPEAPKVLTDAERSSLLSSG 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AG RTDPLPRQ L D+ DR++GSVGRW+ VA LAVLT++V IA NTFGG RDV Sbjct 301 AGAAGPSRTDPLPRQVLADSGEDRTVGSVGRWIVAVAALAVLTIIVVIAFNTFGGGARDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAIA LQNRGFK RTLQKPDS IPPDHVIGTDP AN SVSAGDEIT+NV Sbjct 361 QVPDVRGQVSADAIAALQNRGFKTRTLQKPDSAIPPDHVIGTDPGANASVSAGDEITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L+Y++AV KL AAGF +FKQANSPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQREVPDVSSLSYSDAVTKLKAAGFSKFKQANSPSTPELLGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ +IVGSGP TK +PD+AGQTVD+AQKNL VYGFTK +Q VDSPRP GEV GTNPP Sbjct 481 TNVITLIVGSGPETKQVPDIAGQTVDIAQKNLTVYGFTKITQVQVDSPRPVGEVIGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G TVPVDSVIELQVSKGNQF+MPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGG+Q Sbjct 541 KGQTVPVDSVIELQVSKGNQFIMPDLSGMFWTDAEPRLRALGWTGILDKGPDVDAGGAQS 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 +RVVYQNPPAG GVNRDGIITL+FGQ Sbjct 601 HRVVYQNPPAGAGVNRDGIITLKFGQ 626 >gi|41406114|ref|NP_958950.1| PknB [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394462|gb|AAS02333.1| PknB [Mycobacterium avium subsp. paratuberculosis K-10] Length=626 Score = 1127 bits (2914), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/626 (87%), Positives = 580/626 (93%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAETP+GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPSIVAVYDTGEAETPSGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SADLDAVVLKALAKNP+NRYQTA EMRADLVRVHNGE PEAPKVLTDAER+SLLSS Sbjct 241 EGISADLDAVVLKALAKNPDNRYQTAVEMRADLVRVHNGEKPEAPKVLTDAERSSLLSSG 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AG RTDPLPRQ L D+ DR++GSVGRW+ VA LAVLT++V IA NTFGG RDV Sbjct 301 AGAAGPSRTDPLPRQVLADSGEDRTVGSVGRWIVAVAALAVLTIIVVIAFNTFGGGARDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAIA LQNRGFK RTLQKPDS IPPDHVIGTDP AN SVSAGDEIT+NV Sbjct 361 QVPDVRGQVSADAIAALQNRGFKTRTLQKPDSAIPPDHVIGTDPGANASVSAGDEITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L+Y++AV KL AAGF +FKQANSPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQREVPDVSSLSYSDAVTKLKAAGFSKFKQANSPSTPELLGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ +IVGSGP TK +PD+AGQTVD+AQKNL VYGFTK +Q VDSPRPAGEV GTNPP Sbjct 481 TNVITLIVGSGPETKQVPDIAGQTVDIAQKNLTVYGFTKITQVQVDSPRPAGEVIGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G TVPVDSVIELQVSKGNQF+MPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGG+Q Sbjct 541 KGQTVPVDSVIELQVSKGNQFIMPDLSGMFWTDAEPRLRALGWTGILDKGPDVDAGGAQS 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 +RVVYQNPPAG GVNRDGIITL+FGQ Sbjct 601 HRVVYQNPPAGAGVNRDGIITLKFGQ 626 >gi|118615935|ref|YP_904267.1| serine/threonine-protein kinase B PknB [Mycobacterium ulcerans Agy99] gi|118568045|gb|ABL02796.1| serine/threonine-protein kinase B PknB [Mycobacterium ulcerans Agy99] Length=626 Score = 1124 bits (2908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 558/626 (90%), Positives = 591/626 (95%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELG+ILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGDILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETP+GPLPYIVMEYV+G TLRDIVHT+GPM P RAIE+IA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPSGPLPYIVMEYVNGFTLRDIVHTDGPMAPTRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDPIPPS RH Sbjct 181 QYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPIPPSERH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+ A+LDAVVLKALAKNP+NRYQTAAEMRADLVRVHNGE PEAPKVLT AER SL +S+ Sbjct 241 EGIFAELDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGEAPEAPKVLTGAERRSLTTSS 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 + + PRTDPLPRQ LDDTDRDRS SVGRWVAVVAVLAVLT+VVTIAINTFGG TR+V Sbjct 301 PSSPAAPRTDPLPRQTLDDTDRDRSTPSVGRWVAVVAVLAVLTIVVTIAINTFGGNTRNV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVP+VRGQ+SADAIA LQNRGFK RTL KPDSTIPPDHVIGTDPAAN SVSAGD+IT+NV Sbjct 361 QVPNVRGQASADAIAALQNRGFKTRTLLKPDSTIPPDHVIGTDPAANASVSAGDQITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS++TYAEAVKKLTAAGFGRFK+A SPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQRELPDVSSMTYAEAVKKLTAAGFGRFKEAKSPSTPELMGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ IIVGSGPATK IPDVAGQ+V+ AQ+NLNVYGFTKFSQASVDSP+PAG V TNPP Sbjct 481 TNVITIIVGSGPATKQIPDVAGQSVEEAQQNLNVYGFTKFSQASVDSPKPAGSVIATNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 AGTTVP+DSVIELQVSKGNQFVMPDLSGMFW DAEPRLRALGWTG LDKG DVD GGSQH Sbjct 541 AGTTVPIDSVIELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGSLDKGPDVDGGGSQH 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRVVYQNPPAG GVNRDGI+TL+FGQ Sbjct 601 NRVVYQNPPAGAGVNRDGIVTLKFGQ 626 >gi|342860265|ref|ZP_08716917.1| serine/threonine protein kinase [Mycobacterium colombiense CECT 3035] gi|342132643|gb|EGT85872.1| serine/threonine protein kinase [Mycobacterium colombiense CECT 3035] Length=626 Score = 1123 bits (2906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/626 (87%), Positives = 579/626 (93%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAETP GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPSIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGDTVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SADLDAVVLKALAKNP+NRYQTAAEMRADL+RVHNGE PEAPKVLTDA+R+SLLSS Sbjct 241 EGISADLDAVVLKALAKNPDNRYQTAAEMRADLIRVHNGEKPEAPKVLTDADRSSLLSSG 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 G RTDPLPRQ L D DRS+GSVGRW+ VA LAVLT+VV IA NTFGG RDV Sbjct 301 PGATGPSRTDPLPRQVLADAGEDRSVGSVGRWIVAVAALAVLTIVVVIAFNTFGGGARDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAIA LQNRGFK RTLQKPDSTIPPDHVIGTDP AN SV+AGDEIT+NV Sbjct 361 QVPDVRGQVSADAIAALQNRGFKTRTLQKPDSTIPPDHVIGTDPGANASVNAGDEITINV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L+Y++AV KL AAGF +FKQANSPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQREVPDVSSLSYSDAVTKLKAAGFSKFKQANSPSTPELLGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNVV +IVGSGP TK +PD+AGQTVD+AQKNL VYGF+K +Q VDS RPAGEV GTNPP Sbjct 481 TNVVTLIVGSGPETKQVPDIAGQTVDIAQKNLTVYGFSKVTQVQVDSSRPAGEVIGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G VPVDSVIELQVSKGNQF+MPDLSGMFW DAEPRLRALGWTG+LDKGADVDAGGSQ Sbjct 541 KGQMVPVDSVIELQVSKGNQFIMPDLSGMFWTDAEPRLRALGWTGILDKGADVDAGGSQS 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 +RVVYQNPPAG+GVNRDGIITL+FGQ Sbjct 601 HRVVYQNPPAGSGVNRDGIITLKFGQ 626 >gi|254821346|ref|ZP_05226347.1| serine/threonine protein kinase [Mycobacterium intracellulare ATCC 13950] Length=626 Score = 1120 bits (2896), Expect = 0.0, Method: Compositional matrix adjust. Identities = 539/626 (87%), Positives = 578/626 (93%), Gaps = 0/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAETP GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPSIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPF GDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 +G+S DLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGE PEAPKV TDA+R+S+LSS Sbjct 241 DGISPDLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEKPEAPKVFTDADRSSMLSSN 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 G+ PRTDPLPRQ L D DR++GSVGRW+ VA LAVLT+VV IA NTFGG RDV Sbjct 301 PGSGGPPRTDPLPRQVLADAGEDRTVGSVGRWIVAVAALAVLTIVVVIAFNTFGGGARDV 360 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAIA LQNRGFK RTLQKPDS +PPDHVIGTDP AN SVSAGDEITVNV Sbjct 361 QVPDVRGQVSADAIAALQNRGFKTRTLQKPDSIVPPDHVIGTDPGANASVSAGDEITVNV 420 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L+Y++AV KL AAGF +FKQANSPSTPEL+GKVIGTNPPANQTSAI Sbjct 421 STGPEQREVPDVSSLSYSDAVTKLKAAGFTKFKQANSPSTPELLGKVIGTNPPANQTSAI 480 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ +IVGSGP TK +PD+AGQTVD+AQ+NL VYGF+K +Q VDSPRPAGEV GTNPP Sbjct 481 TNVITVIVGSGPETKQVPDIAGQTVDIAQRNLTVYGFSKVTQVQVDSPRPAGEVIGTNPP 540 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G VPVDSVIELQVSKGNQFVMPDLSGMFW DAEPRLRALGWTG+LDKGADVDAGGSQ Sbjct 541 KGQMVPVDSVIELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGILDKGADVDAGGSQS 600 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 +RVVYQNPPAG+GVNRDGIITL+FGQ Sbjct 601 HRVVYQNPPAGSGVNRDGIITLKFGQ 626 >gi|296167117|ref|ZP_06849526.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897521|gb|EFG77118.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=624 Score = 1117 bits (2890), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/626 (87%), Positives = 579/626 (93%), Gaps = 2/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAETP GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPSIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMIS+TNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISSTNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGD+VDARSDVYSLGCVLYE+LTGEPPFTGDSPV+VAYQHVREDPIPPS RH Sbjct 181 QYLSPEQARGDTVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPIPPSRRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+SADLDAVVLKALAKNP+NRYQTAAEMRADLVRVHNGEPPEAPKVLTDA+RTS L+S Sbjct 241 EGISADLDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGEPPEAPKVLTDADRTSFLAS- 299 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 GN GPRTDPLPRQ L D D + GSVGRW+ VA LAVLT+VV IA NTFGG RDV Sbjct 300 GGNAPGPRTDPLPRQPLRPID-DSNGGSVGRWIVAVAALAVLTIVVVIAFNTFGGTARDV 358 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAIA LQNRGFK RTLQKPDSTIPPDHVI TDP AN SVSAGDEIT+NV Sbjct 359 QVPDVRGQVSADAIAALQNRGFKTRTLQKPDSTIPPDHVINTDPGANASVSAGDEITINV 418 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L+Y++AV KL AAGF +FKQANSPS+PEL+GKVIGTNPPANQTSAI Sbjct 419 STGPEQREVPDVSSLSYSDAVSKLKAAGFSKFKQANSPSSPELLGKVIGTNPPANQTSAI 478 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ +IVGSGP TK +PDVAGQT+DVAQKNL VYGFTK +QA VDS RPAGEV GTNPP Sbjct 479 TNVITVIVGSGPETKQVPDVAGQTIDVAQKNLTVYGFTKITQAQVDSTRPAGEVIGTNPP 538 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G VPVDSVIELQVSKGNQFVMPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGGSQ Sbjct 539 KGQMVPVDSVIELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGVLDKGPDVDAGGSQS 598 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 +RVVYQNPPAGTG N+DGIITL+FGQ Sbjct 599 HRVVYQNPPAGTGCNKDGIITLKFGQ 624 >gi|2344821|emb|CAA94718.1| serine-threonine protein kinase [Mycobacterium leprae] Length=622 Score = 1093 bits (2826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/626 (87%), Positives = 575/626 (92%), Gaps = 4/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELG+ILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPPHLSDRYELGDILGFGGMSEVHLARDIRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAET AGPLPYIVMEYVDG TLRDIVHT+GPM P++AIE++A Sbjct 61 QNAAALNHPSIVAVYDTGEAETSAGPLPYIVMEYVDGATLRDIVHTDGPMPPQQAIEIVA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADS SVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADS-TSVTQTAAVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYE+LTGEPPF GDSPVSVAYQHVREDPIPPS RH Sbjct 180 QYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPPFIGDSPVSVAYQHVREDPIPPSQRH 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+S DLDAVVLKALAKNPENRYQTAAEMRADL+RVH+G+PPEAPKVLTDA+R+ LLSS Sbjct 240 EGISVDLDAVVLKALAKNPENRYQTAAEMRADLIRVHSGQPPEAPKVLTDADRSCLLSSG 299 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGNL PRTD L RQ LD+T+ D GS+GRWVAVVAVLAVLT+ + A NTFGG TRDV Sbjct 300 AGNLCVPRTDALSRQSLDETESD---GSIGRWVAVVAVLAVLTIAIVAAFNTFGGNTRDV 356 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAI+ LQNRGFK RTLQKPDSTIPPDHVI T+P AN SV AGDEIT+NV Sbjct 357 QVPDVRGQVSADAISALQNRGFKTRTLQKPDSTIPPDHVISTEPGANASVGAGDEITINV 416 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L Y +AVKKLT++GF FKQANSPSTPEL+GKVIGTNP ANQTSAI Sbjct 417 STGPEQREVPDVSSLNYTDAVKKLTSSGFKSFKQANSPSTPELLGKVIGTNPSANQTSAI 476 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ IIVGSGP TK IPDV GQ V++AQKNLNVYGFTKFSQASVDSPRP GEV GTNPP Sbjct 477 TNVITIIVGSGPETKQIPDVTGQIVEIAQKNLNVYGFTKFSQASVDSPRPTGEVIGTNPP 536 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 TVPVDSVIELQVSKGNQFVMPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGGSQH Sbjct 537 KDATVPVDSVIELQVSKGNQFVMPDLSGMFWADAEPRLRALGWTGVLDKGPDVDAGGSQH 596 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRV YQNPPAG GVNRDGIITL+FGQ Sbjct 597 NRVAYQNPPAGAGVNRDGIITLKFGQ 622 >gi|15826879|ref|NP_301142.1| serine/threonine protein kinase [Mycobacterium leprae TN] gi|221229357|ref|YP_002502773.1| putative serine/threonine protein kinase [Mycobacterium leprae Br4923] gi|13432242|sp|P54744.3|PKNB_MYCLE RecName: Full=Serine/threonine-protein kinase pknB gi|13092426|emb|CAC29524.1| putative serine/threonine protein kinase [Mycobacterium leprae] gi|219932464|emb|CAR70109.1| putative serine/threonine protein kinase [Mycobacterium leprae Br4923] Length=622 Score = 1092 bits (2823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/626 (87%), Positives = 574/626 (92%), Gaps = 4/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELG+ILGFGGMSEVHLARD+RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPPHLSDRYELGDILGFGGMSEVHLARDIRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHP+IVAVYDTGEAET AGPLPYIVMEYVDG TLRDIVHT+GPM P++AIE++A Sbjct 61 QNAAALNHPSIVAVYDTGEAETSAGPLPYIVMEYVDGATLRDIVHTDGPMPPQQAIEIVA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADS SVTQTAAVIGTA Sbjct 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADS-TSVTQTAAVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYE+LTGEPPF GDSPVSVAYQHVREDPIPPS RH Sbjct 180 QYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPPFIGDSPVSVAYQHVREDPIPPSQRH 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+S DLDAVVLKALAKNPENRYQTAAEMRADL+RVH+G+PPEAPKVLTDA+R+ LLSS Sbjct 240 EGISVDLDAVVLKALAKNPENRYQTAAEMRADLIRVHSGQPPEAPKVLTDADRSCLLSSG 299 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AGN PRTD L RQ LD+T+ D GS+GRWVAVVAVLAVLT+ + A NTFGG TRDV Sbjct 300 AGNFGVPRTDALSRQSLDETESD---GSIGRWVAVVAVLAVLTIAIVAAFNTFGGNTRDV 356 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDVRGQ SADAI+ LQNRGFK RTLQKPDSTIPPDHVI T+P AN SV AGDEIT+NV Sbjct 357 QVPDVRGQVSADAISALQNRGFKTRTLQKPDSTIPPDHVISTEPGANASVGAGDEITINV 416 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQRE+PDVS+L Y +AVKKLT++GF FKQANSPSTPEL+GKVIGTNP ANQTSAI Sbjct 417 STGPEQREVPDVSSLNYTDAVKKLTSSGFKSFKQANSPSTPELLGKVIGTNPSANQTSAI 476 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TNV+ IIVGSGP TK IPDV GQ V++AQKNLNVYGFTKFSQASVDSPRP GEV GTNPP Sbjct 477 TNVITIIVGSGPETKQIPDVTGQIVEIAQKNLNVYGFTKFSQASVDSPRPTGEVIGTNPP 536 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 TVPVDSVIELQVSKGNQFVMPDLSGMFW DAEPRLRALGWTG+LDKG DVDAGGSQH Sbjct 537 KDATVPVDSVIELQVSKGNQFVMPDLSGMFWADAEPRLRALGWTGVLDKGPDVDAGGSQH 596 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRV YQNPPAG GVNRDGIITL+FGQ Sbjct 597 NRVAYQNPPAGAGVNRDGIITLKFGQ 622 >gi|333988655|ref|YP_004521269.1| serine/threonine-protein kinase [Mycobacterium sp. JDM601] gi|333484622|gb|AEF34014.1| serine/threonine-protein kinase B PknB [Mycobacterium sp. JDM601] Length=624 Score = 997 bits (2577), Expect = 0.0, Method: Compositional matrix adjust. Identities = 487/626 (78%), Positives = 549/626 (88%), Gaps = 2/626 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP LSDRYELGEILGFGGMSEVH A D RLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQRLSDRYELGEILGFGGMSEVHRAVDTRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEA+TPAGPLPYIVME V+GVTLRDIV +GPM P RAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEADTPAGPLPYIVMELVEGVTLRDIVQNDGPMPPIRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQ+GIIHRDVKPANIMI NAVKVMDFGIARAIAD+GNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQHGIIHRDVKPANIMIDKHNAVKVMDFGIARAIADAGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVLYE+LTG+ PF GDSPV+VAYQHVREDP+PPS Sbjct 181 QYLSPEQARGEPVDARSDVYSLGCVLYEILTGDAPFIGDSPVAVAYQHVREDPVPPSQHQ 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 GL ADLDAVVLKALAKNP+NRYQTAAEMRADLVRVHNGE PEAP+VLT+A+R ++L+S Sbjct 241 PGLPADLDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGEKPEAPRVLTEADRAAMLASR 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 AG SG TDPLPRQ+L D +R GSVGRW+ VLAVLTV+VT++IN+FGG T + Sbjct 301 AGGGSGAPTDPLPRQEL-DFGHERP-GSVGRWLIAAIVLAVLTVIVTVSINSFGGRTHQI 358 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDV G++S DAIA LQN+GFK RT Q+ DS +PPDHVI T+P A + GD+ITVNV Sbjct 359 QVPDVSGRASVDAIAELQNKGFKTRTEQRADSDVPPDHVISTEPPAGAPANKGDKITVNV 418 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 S GPEQR++PDV++L+YA+AVKKLTAAGFG+FKQ +SPSTPEL KV+GTNPPANQT+AI Sbjct 419 SYGPEQRQVPDVASLSYADAVKKLTAAGFGKFKQVDSPSTPELKDKVVGTNPPANQTTAI 478 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 TN ++I++GSGPATK +PDV GQTV++AQKNL VYGFTK ++ +VDSPRPAG V GT+PP Sbjct 479 TNEIVIVMGSGPATKPVPDVTGQTVELAQKNLTVYGFTKITEVAVDSPRPAGVVIGTSPP 538 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 +G T P+D V+ELQVS+GNQFVMPDL+GMFW DAEP+LRALGWTGML KGADVDAGGS H Sbjct 539 SGETAPLDGVVELQVSRGNQFVMPDLAGMFWTDAEPQLRALGWTGMLIKGADVDAGGSGH 598 Query 601 NRVVYQNPPAGTGVNRDGIITLRFGQ 626 NRV+YQ+P AG GVN DG ITLRFGQ Sbjct 599 NRVLYQSPSAGQGVNTDGNITLRFGQ 624 >gi|145221406|ref|YP_001132084.1| protein kinase [Mycobacterium gilvum PYR-GCK] gi|315441714|ref|YP_004074593.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] gi|145213892|gb|ABP43296.1| serine/threonine protein kinase [Mycobacterium gilvum PYR-GCK] gi|315260017|gb|ADT96758.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] Length=625 Score = 951 bits (2459), Expect = 0.0, Method: Compositional matrix adjust. Identities = 472/628 (76%), Positives = 529/628 (85%), Gaps = 9/628 (1%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYE+GEILGFGGMSEVHLARDLRLHRDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYEVGEILGFGGMSEVHLARDLRLHRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETP GPLPYIVMEYVDGVTLRDIVH++GPM P+RAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHSDGPMPPQRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQ+GIIHRDVKPANIMIS T AVKVMDFGIARA+AD+GN VTQTAAVIGTA Sbjct 121 DACQALNFSHQHGIIHRDVKPANIMISKTGAVKVMDFGIARALADAGNPVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG VDARSDVYSLGCVLYE+LTGEPPF GDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGVKVDARSDVYSLGCVLYEMLTGEPPFVGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 G+S +LDAVVLKALAKNP+NRYQTAAEMR+DLV+VH+GE P+APKV TDAERTSLL+S Sbjct 241 TGISPELDAVVLKALAKNPDNRYQTAAEMRSDLVKVHSGEIPDAPKVFTDAERTSLLAST 300 Query 301 AGNLSGPRTDPL----PRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGI 356 +L DP+ PR D +R+R GS+GRW+ VAVLAVLTV+VTI IN FGG Sbjct 301 PAHLRTEPVDPVGPHQPRYD----ERERG-GSLGRWLIAVAVLAVLTVLVTIGINAFGGE 355 Query 357 TRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEI 416 TR+VQVPDV GQ+SADAIATLQNRGF IRT QKPDS +PPDHVI TDP ANTSV+AGDEI Sbjct 356 TREVQVPDVSGQASADAIATLQNRGFSIRTQQKPDSEVPPDHVIDTDPNANTSVAAGDEI 415 Query 417 TVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQ 476 T+NVSTGPEQRE+PDVS L+YA+AV++LT AGF RF+Q S S PE +V+ T PPANQ Sbjct 416 TLNVSTGPEQREVPDVSGLSYADAVRRLTDAGFERFRQTTSTSLPEQKDRVLSTVPPANQ 475 Query 477 TSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTG 536 TSAITN + +++G GPAT +P+ GQTV+ Q+ L+ GFTK VDS AG+V G Sbjct 476 TSAITNEITVVIGKGPATAVVPECVGQTVETCQQILSASGFTKAVPVEVDSTVSAGQVVG 535 Query 537 TNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAG 596 P G TVP DSVI++QVS+GNQFVMPDL+G FW DAEPRLRALGWTG+LDKG DV Sbjct 536 IEPAPGQTVPQDSVIQIQVSRGNQFVMPDLTGQFWTDAEPRLRALGWTGVLDKGGDVQNS 595 Query 597 GSQHNRVVYQNPPAGTGVNRDGIITLRF 624 G + N VV Q+P AG+GVN ITL F Sbjct 596 GQRTNAVVRQSPSAGSGVNYGATITLNF 623 >gi|120401051|ref|YP_950880.1| protein kinase [Mycobacterium vanbaalenii PYR-1] gi|119953869|gb|ABM10874.1| serine/threonine protein kinase [Mycobacterium vanbaalenii PYR-1] Length=625 Score = 947 bits (2449), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/627 (76%), Positives = 525/627 (84%), Gaps = 7/627 (1%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYE+GEILGFGGMSEVHLARDLRLHRDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYEVGEILGFGGMSEVHLARDLRLHRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETP GPLPYIVMEYVDGVTLRDIVH +GPM P+RAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHNDGPMAPQRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQ+GIIHRDVKPANIMIS T AVKVMDFGIARA+AD+GN VTQTAAVIGTA Sbjct 121 DACQALNFSHQHGIIHRDVKPANIMISKTGAVKVMDFGIARALADAGNPVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG VDARSDVYSLGCVLYEVLTGEPPF GDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGVKVDARSDVYSLGCVLYEVLTGEPPFVGDSPVAVAYQHVREDPVPPSQRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 G+S +LDAVVLKALAKNP+NRYQTAAEMR DLVRVH+GE P+APKV TDAERTSLL Sbjct 241 AGISPELDAVVLKALAKNPDNRYQTAAEMRTDLVRVHSGEAPDAPKVFTDAERTSLL--- 297 Query 301 AGNLSGPRTDPLP---RQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGIT 357 A N + RT+P+ R+ + +R GS+GRW+ VA+LAVLTVVVTI IN FGG T Sbjct 298 AANPAHHRTEPVEPAGRRQPRYAEPERG-GSLGRWLIAVAILAVLTVVVTIGINMFGGGT 356 Query 358 RDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEIT 417 RDVQVPDVRGQ+SADAIATLQNRGF IRT QKPDS +PPDHVI TDP ANT V AGDEIT Sbjct 357 RDVQVPDVRGQASADAIATLQNRGFSIRTQQKPDSEVPPDHVIDTDPGANTEVGAGDEIT 416 Query 418 VNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQT 477 +NVSTGPEQRE+PDVS L+Y EAV++LT AGF +F+Q S S PE +V+ T PPANQT Sbjct 417 LNVSTGPEQREVPDVSGLSYTEAVRRLTEAGFEKFRQTASTSLPEQKDRVLSTVPPANQT 476 Query 478 SAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGT 537 SAITN + I+VG GPAT +P+ GQTV+V Q+ L+ GFTK VDS AG+V G Sbjct 477 SAITNEITIVVGKGPATAVVPECVGQTVEVCQQILSASGFTKSVPVEVDSTVAAGQVVGL 536 Query 538 NPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGG 597 P AG TVP D+VI++QVS+GNQFVMPDL G FW DAEPRLRALGWTG+LDKGADV G Sbjct 537 EPAAGQTVPQDTVIQIQVSRGNQFVMPDLRGQFWADAEPRLRALGWTGVLDKGADVPNSG 596 Query 598 SQHNRVVYQNPPAGTGVNRDGIITLRF 624 + N VV Q+P G+GVN ITL F Sbjct 597 QRTNAVVTQSPSPGSGVNYGSRITLNF 623 >gi|108796996|ref|YP_637193.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119866080|ref|YP_936032.1| serine/threonine protein kinase [Mycobacterium sp. KMS] gi|108767415|gb|ABG06137.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119692169|gb|ABL89242.1| serine/threonine protein kinase [Mycobacterium sp. KMS] Length=624 Score = 941 bits (2433), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/627 (77%), Positives = 536/627 (86%), Gaps = 8/627 (1%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD RLHRDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDNRLHRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVH+EGPM PKRA+EVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHSEGPMPPKRALEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQ+GIIHRDVKPANIMIS T AVKVMDFGIARA+ADS +SVTQTAAVIGTA Sbjct 121 DACQALNFSHQHGIIHRDVKPANIMISKTGAVKVMDFGIARALADS-SSVTQTAAVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVLYE+LTGEPPF GDSPV+VAYQHVREDP+PPS RH Sbjct 180 QYLSPEQARGEKVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPPSQRH 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+S DLDAVVLKALAKNP+NRYQTAAE+R+DLVRVH+GEPPEAPKV TDAERTS+LS+A Sbjct 240 EGVSRDLDAVVLKALAKNPDNRYQTAAELRSDLVRVHSGEPPEAPKVFTDAERTSMLSAA 299 Query 301 AGNLSGPRTDPL---PRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGIT 357 RT+P+ PR + +R+R GS+GRW+A VAVLAVLTVVV +AINT+GG T Sbjct 300 P---HPGRTEPMTHMPRPEPRLVERNRG-GSIGRWIAAVAVLAVLTVVVAVAINTYGGET 355 Query 358 RDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEIT 417 R VQVPDVRG+ SA+AIA LQN GF +RT +P+S + PDHVI T P ANT AG+EIT Sbjct 356 RAVQVPDVRGEVSAEAIAQLQNAGFTVRTQNEPNSEVAPDHVISTSPEANTEADAGEEIT 415 Query 418 VNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQT 477 +NVSTGPEQRE+PDV +LTYAEAV+KLT AGFGRF+Q SPSTPEL +V+ TNPPANQT Sbjct 416 LNVSTGPEQREVPDVKSLTYAEAVRKLTDAGFGRFRQQASPSTPELKDRVMATNPPANQT 475 Query 478 SAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGT 537 SAITN V II+GSGP T+ +P+V GQTV+ AQ+ L GF A VDS PAG+V GT Sbjct 476 SAITNEVTIIIGSGPQTRAVPEVVGQTVESAQQILTASGFRNSVPAEVDSTEPAGQVLGT 535 Query 538 NPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGG 597 +P AG VPVD++I+LQVS+GNQFVMPDL+G FW DAEPRLRALGWTG+LDKG DV G Sbjct 536 SPTAGENVPVDTLIQLQVSRGNQFVMPDLTGQFWTDAEPRLRALGWTGVLDKGGDVQNSG 595 Query 598 SQHNRVVYQNPPAGTGVNRDGIITLRF 624 + N VV Q PP GTGVN D ITL F Sbjct 596 QRTNAVVRQTPPPGTGVNFDSRITLNF 622 >gi|126432628|ref|YP_001068319.1| serine/threonine protein kinase [Mycobacterium sp. JLS] gi|126232428|gb|ABN95828.1| serine/threonine protein kinase [Mycobacterium sp. JLS] Length=624 Score = 939 bits (2426), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/627 (77%), Positives = 535/627 (86%), Gaps = 8/627 (1%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARD RLHRDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDNRLHRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVH+EGPM PKRA+EVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHSEGPMPPKRALEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQ+GIIHRDVKPANIMIS T AVKVMDFGIARA+ADS +SVTQTAAVIGTA Sbjct 121 DACQALNFSHQHGIIHRDVKPANIMISKTGAVKVMDFGIARALADS-SSVTQTAAVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVLYE+LTGEPPF GDSPV+VAYQHVREDP+PPS RH Sbjct 180 QYLSPEQARGEKVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPPSQRH 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EG+S DLDAVVLKALAKNP+NRYQTAAE+R+DLVRVH+GEPPEAPKV TDAERTS+LS+A Sbjct 240 EGVSRDLDAVVLKALAKNPDNRYQTAAELRSDLVRVHSGEPPEAPKVFTDAERTSMLSAA 299 Query 301 AGNLSGPRTDPL---PRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGIT 357 RT+P+ PR + +R+R GS+GRW+A VAVLAVLTVVV +AINT+GG T Sbjct 300 P---HPGRTEPMTHMPRPEPRLVERNRG-GSIGRWIAAVAVLAVLTVVVAVAINTYGGET 355 Query 358 RDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEIT 417 R VQVPDVRG+ SA+AIA LQN GF +RT +P+S + PDHVI T P ANT AG+EIT Sbjct 356 RAVQVPDVRGEVSAEAIAQLQNAGFTVRTQNEPNSEVAPDHVISTSPEANTEADAGEEIT 415 Query 418 VNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQT 477 +NVSTGPEQRE+PDV +LTYAEAV+ LT AGFGRF+Q SPSTPEL +V+ TNPPANQT Sbjct 416 LNVSTGPEQREVPDVKSLTYAEAVRTLTDAGFGRFRQQASPSTPELKDRVMATNPPANQT 475 Query 478 SAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGT 537 SAITN V II+GSGP T+ +P+V GQTV+ AQ+ L GF A VDS PAG+V GT Sbjct 476 SAITNEVTIIIGSGPQTRAVPEVVGQTVESAQQILTASGFRNSVPAEVDSTEPAGQVLGT 535 Query 538 NPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGG 597 +P AG VPVD++I+LQVS+GNQFVMPDL+G FW DAEPRLRALGWTG+LDKG DV G Sbjct 536 SPTAGENVPVDTLIQLQVSRGNQFVMPDLTGQFWTDAEPRLRALGWTGVLDKGGDVQNSG 595 Query 598 SQHNRVVYQNPPAGTGVNRDGIITLRF 624 + N VV Q PP GTGVN D ITL F Sbjct 596 QRTNAVVRQTPPPGTGVNFDSRITLNF 622 >gi|118471844|ref|YP_884449.1| serine-threonine protein kinase [Mycobacterium smegmatis str. MC2 155] gi|118173131|gb|ABK74027.1| serine-threonine protein kinase [Mycobacterium smegmatis str. MC2 155] Length=625 Score = 849 bits (2193), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/624 (71%), Positives = 505/624 (81%), Gaps = 1/624 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETP GPLPYIVMEYVDGVTLRDIVHT+GP+ P+RAIE+IA Sbjct 61 QNAAALNHPAIVAVYDTGEAETPNGPLPYIVMEYVDGVTLRDIVHTDGPIAPRRAIEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQ+GIIHRDVKPANIMIS NAVKVMDFGIARA+AD+GNSVTQTAAVIGTA Sbjct 121 DACQALNFSHQHGIIHRDVKPANIMISKNNAVKVMDFGIARALADTGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG++VDARSDVYSLGCVLYE+LTGEPPF GDSPV+VAYQHVREDP+PPS RH Sbjct 181 QYLSPEQARGETVDARSDVYSLGCVLYEILTGEPPFIGDSPVAVAYQHVREDPVPPSRRH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 ++ +LDAVVLKALAKNP+NRYQTAAEMRADL+RVH G+ P+APKVLTDAERTS+L++ Sbjct 241 ADVTPELDAVVLKALAKNPDNRYQTAAEMRADLIRVHEGQAPDAPKVLTDAERTSMLAAP 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 + +G T +P + RS SV RW+ VAVLAVLTVVVT+AIN GG R+V Sbjct 301 PADRAGAATQDMPVPRPAGYSKQRST-SVARWLIAVAVLAVLTVVVTVAINMVGGNPRNV 359 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNV 420 QVPDV QS+ DA A LQNRGFK ++PD+ +PP VIGTDP A + + AG+++T+NV Sbjct 360 QVPDVAEQSADDAQAALQNRGFKTVIDRQPDNEVPPGLVIGTDPEAGSELGAGEQVTINV 419 Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 STGPEQ +PDV+ LT +A +KL AGF +F+++ SPSTPE G+V+ TNP ANQT+AI Sbjct 420 STGPEQALVPDVAGLTPTQARQKLKDAGFEKFRESPSPSTPEQKGRVLATNPQANQTAAI 479 Query 481 TNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPP 540 N + I+VG+GP + AGQ + + L GFT VD+P AG+V GT P Sbjct 480 INEITIVVGAGPEDAPVLSCAGQNAESCKAILAAGGFTNTVVVEVDNPAAAGQVVGTEPA 539 Query 541 AGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH 600 G +VP D+VI+++VSKGNQFVMPDL G FW DA PRL ALGWTG+LDKG DV G + Sbjct 540 DGQSVPKDTVIQIRVSKGNQFVMPDLVGQFWSDAYPRLTALGWTGVLDKGPDVRDSGQRT 599 Query 601 NRVVYQNPPAGTGVNRDGIITLRF 624 N VV Q+P AGT VN+D ITL F Sbjct 600 NAVVTQSPSAGTPVNKDAKITLSF 623 >gi|169627140|ref|YP_001700789.1| serine/threonine-protein kinase PknB [Mycobacterium abscessus ATCC 19977] gi|169239107|emb|CAM60135.1| Probable serine/threonine-protein kinase PknB [Mycobacterium abscessus] Length=628 Score = 820 bits (2117), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/631 (66%), Positives = 489/631 (78%), Gaps = 11/631 (1%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGEILG+GGMSEVHLARDLRL+RDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MTTPQHLSDRYELGEILGYGGMSEVHLARDLRLNRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET GPLPYIVMEYVDG+TLRDIV +GPM +RAIEVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETATGPLPYIVMEYVDGITLRDIVKDDGPMPIRRAIEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D+CQALNFSHQ+GIIHRDVKPANIMIS T AVKVMDFGIARA++D+GNSVTQTAAVIGTA Sbjct 121 DSCQALNFSHQHGIIHRDVKPANIMISKTGAVKVMDFGIARAVSDAGNSVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG++VDARSDVYSLGCVLYE++TGEPPF GDSPV+VAYQHVREDP+ PS + Sbjct 181 QYLSPEQARGETVDARSDVYSLGCVLYELVTGEPPFVGDSPVAVAYQHVREDPVAPSKHN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + LD+VVLKAL+KNP+NRYQ AAEMRADL+RV+ GE PEAPKVLTDAER+++LS+ Sbjct 241 PEIPPGLDSVVLKALSKNPDNRYQNAAEMRADLMRVYQGEQPEAPKVLTDAERSTMLSTP 300 Query 301 AGN----LSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGI 356 A SGP+T PLP Q ++ R+ + RW+ +A L VLT++VT AI G Sbjct 301 ANTRAFPASGPQTGPLPSQ-YEEPRRN----PLSRWLVGLAALVVLTIIVTFAIILGNGP 355 Query 357 TRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEI 416 +RDVQVPDV G+S +DA+A LQN GFK + + S + P+ VI TDPA ++VSAG E+ Sbjct 356 SRDVQVPDVTGKSQSDAVAALQNLGFKTKVQKNTSSKVAPEKVIDTDPAKGSTVSAGAEV 415 Query 417 TVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGF-GRFKQANSPSTPELVGKVIGTNPPAN 475 TVNVS GPE +++PD L++ +AVKKL AAGF G F Q+ + S PE G+V+ TNPPA Sbjct 416 TVNVSIGPENQQVPDCHGLSFGDAVKKLQAAGFKGTFTQSETKSLPEDKGRVMATNPPAG 475 Query 476 QTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQA-SVDSPRPAGEV 534 Q SA+TN + I+VG GP K +PD+ GQ +DVA KNL YGFT V SP G++ Sbjct 476 QYSAVTNNITIVVGKGPGEKPVPDLGGQNIDVAIKNLPTYGFTAPPTVIPVPSPESKGQI 535 Query 535 TGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVD 594 TNPPA T P D VIE++VS G QF MP++ G FW DAEP L GW G DV Sbjct 536 LSTNPPANTMFPEDGVIEIRVSNGGQFRMPNIMGKFWTDAEPMLYQAGWQGGGLSTEDVP 595 Query 595 AGGSQHNRVVYQNPPAGTGVNRDGIITLRFG 625 + G+ RVV+Q+PPAG GV +G I LRFG Sbjct 596 SDGNNRARVVFQDPPAGAGVGYNGPIKLRFG 626 >gi|298527412|ref|ZP_07014821.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis 94_M4241A] gi|298497206|gb|EFI32500.1| transmembrane serine/threonine-protein kinase b pknb [Mycobacterium tuberculosis 94_M4241A] Length=437 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/377 (99%), Positives = 377/377 (100%), Gaps = 0/377 (0%) Query 250 VVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLSGPRT 309 VVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLSGPRT Sbjct 61 VVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGNLSGPRT 120 Query 310 DPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQS 369 DPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQS Sbjct 121 DPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQS 180 Query 370 SADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPEQREI 429 SADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPEQREI Sbjct 181 SADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPEQREI 240 Query 430 PDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAITNVVIIIVG 489 PDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAIT+VVIIIVG Sbjct 241 PDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAITSVVIIIVG 300 Query 490 SGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDS 549 SGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDS Sbjct 301 SGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDS 360 Query 550 VIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVYQNPP 609 VIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVYQNPP Sbjct 361 VIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVYQNPP 420 Query 610 AGTGVNRDGIITLRFGQ 626 AGTGVNRDGIITLRFGQ Sbjct 421 AGTGVNRDGIITLRFGQ 437 >gi|312137536|ref|YP_004004872.1| serine/threonine kinase pknb [Rhodococcus equi 103S] gi|325677498|ref|ZP_08157162.1| non-specific serine/threonine protein kinase [Rhodococcus equi ATCC 33707] gi|311886875|emb|CBH46183.1| serine/threonine kinase PknB [Rhodococcus equi 103S] gi|325551745|gb|EGD21443.1| non-specific serine/threonine protein kinase [Rhodococcus equi ATCC 33707] Length=643 Score = 633 bits (1632), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 342/640 (54%), Positives = 429/640 (68%), Gaps = 16/640 (2%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP +LS RYELGEILGFGGMSEVHL RDLRL RDVA+KVLRADLARDP+FYLRFRREA Sbjct 1 MTTPRNLSSRYELGEILGFGGMSEVHLGRDLRLSRDVAIKVLRADLARDPTFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET AGPLPYIVMEYVDG TLRDI+ TEGP+ P+RA+EVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETDAGPLPYIVMEYVDGDTLRDIIRTEGPLQPRRAMEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH+NGI+HRD+KPANIMI+ AVKVMDFGIARAI+DS + +TQTAAVIGTA Sbjct 121 DVCAALDFSHRNGIVHRDMKPANIMINRAGAVKVMDFGIARAISDSSSPMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVLYEVLTGEPPF GDSPV+VAYQHVREDP PS + Sbjct 181 QYLSPEQARGEQVDARSDVYSLGCVLYEVLTGEPPFKGDSPVAVAYQHVREDPKQPSQVN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLS-- 298 + LD+V+LKA++KNP NRYQ+AAEMR+DLVRV G+ P AP V++D +RT++ Sbjct 241 PAVPPALDSVILKAMSKNPANRYQSAAEMRSDLVRVLGGQRPSAPMVMSDEDRTTMFGPV 300 Query 299 -SAAGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGIT 357 S AG SG R +P R + + A +L+V + + G Sbjct 301 DSGAGTGSGYRPEPA-RTSTATAAPVAVPAAAPAKKSNTARNTMLSVAALVVVGIIGAFI 359 Query 358 -------RDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSV 410 V+VP+V G ++ A A L+ +PD+ + +VI T P+A +SV Sbjct 360 WSLVSNPAKVEVPNVAGLTAQAAEAQLRGMNLDTSIQTRPDAVVAEGNVIATTPSAGSSV 419 Query 411 SAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQAN-SPSTPELVGKVIG 469 S +T+ VS+GPEQ ++P ++ L+ EA + L A G + + +PS P + KV Sbjct 420 SEKSTVTLQVSSGPEQVQVPKLAGLSQDEAAQALNAVGLRLAPEVDRAPSDPAQLDKVTA 479 Query 470 TNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPR 529 +P + + + V I +GSGP IP+V GQT+DVAQ N+ GF K A+VDS + Sbjct 480 QDPSSGAKINLDSTVSITLGSGPEQVRIPNVIGQTIDVAQPNIEGVGF-KVQVATVDSSK 538 Query 530 PAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTG---M 586 P G+V T+P G+T VI +QVS G QF MPDL+ M A LR GWTG Sbjct 539 PEGQVISTSPSGGSTAAKGDVITVQVSNGKQFTMPDLTEMSVSQAVEALRKAGWTGSSNQ 598 Query 587 LDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 L + S +++ Q PAG+ V ++ +T+ G+ Sbjct 599 LTQTRQSTLDASLVGKILGQQQPAGSDVAKNAPLTVIVGE 638 >gi|28948659|pdb|1MRU|A Chain A, Intracellular SerTHR PROTEIN KINASE DOMAIN OF Mycobacterium Tuberculosis Pknb. gi|28948660|pdb|1MRU|B Chain B, Intracellular SerTHR PROTEIN KINASE DOMAIN OF Mycobacterium Tuberculosis Pknb. Length=311 Score = 630 bits (1625), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 308/308 (100%), Positives = 308/308 (100%), Gaps = 0/308 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 4 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 63 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 64 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 123 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 124 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 183 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 184 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 243 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 244 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 303 Query 301 AGNLSGPR 308 AGNLSGPR Sbjct 304 AGNLSGPR 311 >gi|315113736|pdb|3ORM|A Chain A, Mycobacterium Tuberculosis Pknb Kinase Domain D76a Mutant Length=311 Score = 627 bits (1618), Expect = 2e-177, Method: Compositional matrix adjust. Identities = 307/308 (99%), Positives = 307/308 (99%), Gaps = 0/308 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 4 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 63 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVY TGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 64 QNAAALNHPAIVAVYATGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 123 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 124 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 183 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 184 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 243 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 244 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 303 Query 301 AGNLSGPR 308 AGNLSGPR Sbjct 304 AGNLSGPR 311 >gi|315113730|pdb|3ORI|A Chain A, Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 1) gi|315113731|pdb|3ORI|B Chain B, Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 1) gi|315113732|pdb|3ORI|C Chain C, Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 1) 6 more sequence titles Length=311 Score = 627 bits (1616), Expect = 3e-177, Method: Compositional matrix adjust. Identities = 307/308 (99%), Positives = 307/308 (99%), Gaps = 0/308 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLR HRDVAVKVLRADLARDPSFYLRFRREA Sbjct 4 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRDHRDVAVKVLRADLARDPSFYLRFRREA 63 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 64 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 123 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 124 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 183 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 184 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 243 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 244 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 303 Query 301 AGNLSGPR 308 AGNLSGPR Sbjct 304 AGNLSGPR 311 >gi|111020683|ref|YP_703655.1| serine/threonine protein kinase [Rhodococcus jostii RHA1] gi|110820213|gb|ABG95497.1| probable serine/threonine protein kinase [Rhodococcus jostii RHA1] Length=639 Score = 626 bits (1614), Expect = 4e-177, Method: Compositional matrix adjust. Identities = 340/643 (53%), Positives = 440/643 (69%), Gaps = 28/643 (4%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP +LS RYELGEILGFGGMSEVHLARD+RL RDVA+KVLRADLARDP+FYLRFRREA Sbjct 1 MTTPRNLSSRYELGEILGFGGMSEVHLARDVRLSRDVAIKVLRADLARDPTFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET AGPLPYIVMEYVDG TLRDIV +EGPM P+RA+EVI+ Sbjct 61 QNAAALNHPAIVAVYDTGEAETEAGPLPYIVMEYVDGDTLRDIVRSEGPMAPRRAMEVIS 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH+NGI+HRDVKPAN+MI+ AVKVMDFGIARAI+D+ + +TQTAAVIGTA Sbjct 121 DVCAALDFSHRNGIVHRDVKPANVMINRAGAVKVMDFGIARAISDASSPMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVL+E+LTGEPPF GDSPV+VAYQHVREDP PSA + Sbjct 181 QYLSPEQARGEQVDARSDVYSLGCVLFEILTGEPPFKGDSPVAVAYQHVREDPQTPSAVN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLS-- 298 + +LD+V+LKA++KNP NRYQTAA+MR+DLVRV G+ P AP V++D +RT++L Sbjct 241 PDIPRELDSVILKAMSKNPANRYQTAADMRSDLVRVLGGQRPSAPMVMSDEDRTTILGAV 300 Query 299 -SAAGNLSGPRTDPLP----RQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTF 353 + AGN ++ P P + D + D+ ++ VA++A+ ++V + F Sbjct 301 DTGAGNYRRQQS-PTPATASKTDGGEPDKKKN-------PMRVALMALGALIVVGVVGAF 352 Query 354 ------GGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAAN 407 G V +PDV Q++ DA TLQN GF++ QKPD+ + +VI T P Sbjct 353 LWSVGPGSKADQVTMPDVTNQAADDAETTLQNLGFRVARQQKPDAVVATGNVITTRPVGG 412 Query 408 TSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQ--ANSPSTPELVG 465 V G IT+ VS+GPEQ ++P ++ LT EA ++L A G R A +PS V Sbjct 413 VQVDEGSTITLEVSSGPEQVKVPRLAGLTQQEAQQELNAVGL-RLDTAVARAPSDVSDVD 471 Query 466 KVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASV 525 KVI NP + + ++ + V + +G+GP IPDV GQ V+VAQ N+ GF K ++ Sbjct 472 KVIDQNPSSGASISLDSEVAVTLGTGPEQIRIPDVTGQKVEVAQANIEGAGF-KAQIQNI 530 Query 526 DSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLR---ALG 582 DS P G+V T+P G+T I+++VS GN MPDL+G A LR G Sbjct 531 DSGAPKGQVVSTDPVGGSTAAKGDTIQIRVSNGNNIEMPDLTGKTVSQALAELRSAGWSG 590 Query 583 WTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFG 625 + L++ +++ Q P G+ + ++G++++ G Sbjct 591 SSSSLNQTQTSTLDPEMVGKIISQEQPPGSEITKNGVVSVGVG 633 >gi|215794787|pdb|3F61|A Chain A, Crystal Structure Of M. Tuberculosis Pknb Leu33aspVAL222ASP DOUBLE MUTANT IN COMPLEX WITH ADP Length=311 Score = 624 bits (1609), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 306/308 (99%), Positives = 306/308 (99%), Gaps = 0/308 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLR HRDVAVKVLRADLARDPSFYLRFRREA Sbjct 4 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRDHRDVAVKVLRADLARDPSFYLRFRREA 63 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 64 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 123 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 124 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 183 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSP SVAYQHVREDPIPPSARH Sbjct 184 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPDSVAYQHVREDPIPPSARH 243 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 244 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 303 Query 301 AGNLSGPR 308 AGNLSGPR Sbjct 304 AGNLSGPR 311 >gi|226362923|ref|YP_002780703.1| serine/threonine protein kinase PknB [Rhodococcus opacus B4] gi|226241410|dbj|BAH51758.1| serine/threonine protein kinase PknB [Rhodococcus opacus B4] Length=639 Score = 624 bits (1609), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 339/635 (54%), Positives = 432/635 (69%), Gaps = 12/635 (1%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP +LS RYELGEILGFGGMSEVHLARD+RL RDVA+KVLRADLARDP+FYLRFRREA Sbjct 1 MTTPRNLSSRYELGEILGFGGMSEVHLARDVRLSRDVAIKVLRADLARDPTFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET AGPLPYIVMEYVDG TLRDIV EGPM P+RA+EVI+ Sbjct 61 QNAAALNHPAIVAVYDTGEAETDAGPLPYIVMEYVDGDTLRDIVRGEGPMAPRRAMEVIS 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH+NGI+HRDVKPAN+MI+ AVKVMDFGIARAI+D+ + +TQTAAVIGTA Sbjct 121 DVCAALDFSHRNGIVHRDVKPANVMINRAGAVKVMDFGIARAISDASSPMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVL+E+LTGEPPF GDSPV+VAYQHVREDP PS + Sbjct 181 QYLSPEQARGEQVDARSDVYSLGCVLFEILTGEPPFKGDSPVAVAYQHVREDPQTPSVVN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLS-- 298 + +LD+V+LKA++KNP NRYQTAA+MR+DLVRV G+ P AP V++D +RT++L Sbjct 241 PDIPRELDSVILKAMSKNPANRYQTAADMRSDLVRVLGGQRPSAPMVMSDEDRTTILGAV 300 Query 299 -SAAGNLSG-PRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGI 356 S AGN P T D + D+ + + + L V+ +V + G Sbjct 301 DSGAGNYRRPPNTTQTSAAKTDGGEPDKKKNPMRLALMALGALIVVGIVGAFLWSVGPGS 360 Query 357 TRD-VQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDE 415 D V +PDV Q++ DA TLQN GF++ QKPD+ + +VI T P V G Sbjct 361 KADQVTMPDVTNQAADDAETTLQNLGFRVSRQQKPDAVVATGNVITTRPVGGVQVDEGST 420 Query 416 ITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQ--ANSPSTPELVGKVIGTNPP 473 IT+ VS+GPEQ ++P ++ LT EA ++L A G R A +PS V KVI NP Sbjct 421 ITLEVSSGPEQVKVPRLAGLTQDEAQQELNAVGL-RLDTAVARAPSDASDVDKVIQQNPS 479 Query 474 ANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGE 533 + + ++ + V + +G+GP IPDV GQ V+VAQ N+ GF K ++DS P G+ Sbjct 480 SGASISLDSEVAVTLGTGPEQIRIPDVTGQKVEVAQANIEGAGF-KVQIQNIDSGVPKGQ 538 Query 534 VTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLR---ALGWTGMLDKG 590 V T+P G+T I+++VS GN MPDL+G A LR G + L++ Sbjct 539 VVSTDPVGGSTAAKGDTIQIRVSNGNNIEMPDLTGKTVSQALAELRSAGWSGSSASLNQT 598 Query 591 ADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFG 625 +++ Q P G+ + ++G++++ G Sbjct 599 QTSTLDPEMVGKIISQEQPPGSEITKNGVVSVGVG 633 >gi|215794788|pdb|3F69|A Chain A, Crystal Structure Of The Mycobacterium Tuberculosis Pknb Mutant Kinase Domain In Complex With Kt5720 gi|215794789|pdb|3F69|B Chain B, Crystal Structure Of The Mycobacterium Tuberculosis Pknb Mutant Kinase Domain In Complex With Kt5720 Length=311 Score = 620 bits (1600), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 304/308 (99%), Positives = 306/308 (99%), Gaps = 0/308 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLR HRDVAVKVLRADLARDPSFYLRFRREA Sbjct 4 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRDHRDVAVKVLRADLARDPSFYLRFRREA 63 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 64 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 123 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANI+ISATNAVKV+DFGIARAIADSGNSV QTAAVIGTA Sbjct 124 DACQALNFSHQNGIIHRDVKPANILISATNAVKVVDFGIARAIADSGNSVXQTAAVIGTA 183 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 184 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 243 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Sbjct 244 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 303 Query 301 AGNLSGPR 308 AGNLSGPR Sbjct 304 AGNLSGPR 311 >gi|54022044|ref|YP_116286.1| putative serine/threonine protein kinase [Nocardia farcinica IFM 10152] gi|54013552|dbj|BAD54922.1| putative serine/threonine protein kinase [Nocardia farcinica IFM 10152] Length=635 Score = 618 bits (1594), Expect = 9e-175, Method: Compositional matrix adjust. Identities = 337/634 (54%), Positives = 428/634 (68%), Gaps = 13/634 (2%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP +LS RYELGEI+GFGGMSEVH ARDLRL RDVA+KVLRADLARDP+FYLRF+REA Sbjct 1 MTTPKNLSARYELGEIIGFGGMSEVHKARDLRLSRDVAIKVLRADLARDPTFYLRFKREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAE GPLPYIVMEYVDG TLRDIV +GP+ P+RA+E+IA Sbjct 61 QNAAALNHPAIVAVYDTGEAEIDGGPLPYIVMEYVDGETLRDIVRGKGPLPPRRAMEIIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH++GI+HRD+KPANIMI+ + AVKVMDFGIARA+ADS N +TQTAAVIGTA Sbjct 121 DVCAALDFSHKHGIVHRDMKPANIMINRSGAVKVMDFGIARALADSSNPMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG++VDARSDVYS+GCVL+E+LTGEPPFTGDSPV+VAYQHVREDP PS H Sbjct 181 QYLSPEQARGETVDARSDVYSVGCVLFEILTGEPPFTGDSPVAVAYQHVREDPRLPSHVH 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 G+ +LD+VVLKA++KNP NRYQTAAEMRADL+RV G+ P AP V+TD +RT+ + + Sbjct 241 HGVPRELDSVVLKAMSKNPANRYQTAAEMRADLIRVLGGQKPSAPMVMTDEDRTTFMGA- 299 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTF----GGI 356 + GPRT +D D +++ + + GR A +A A + V A+ G Sbjct 300 --DEPGPRTYRAVERDDDTAEQEPAEPNSGRRTAYLAFGAAAVLAVAFALFWVLIGPGSK 357 Query 357 TRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEI 416 V VPD+ +S+ A TLQ GF + QKPDS + +VI T P + + G + Sbjct 358 PDQVAVPDLSNKSAQQAQDTLQRLGFTVAIQQKPDSKVAVGNVISTQPLGGSRIDKGSTV 417 Query 417 TVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQAN-SPSTPELVGKVIGTNPPAN 475 TV VS+GP Q ++P + L+ +A ++L A G S+ + + KVIGT P A Sbjct 418 TVQVSSGPAQVQVPRLDGLSVQQAEQELNAVGLRMDPNVERRESSAQDLDKVIGTEPGAG 477 Query 476 QTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNL-NVYGFTKFSQASVDSPRPAGEV 534 + +++ VG GP +P V GQ + VAQ NL + GF K V S RP GEV Sbjct 478 ARVDVDQAIVVWVGKGPEKVRVPSVVGQDISVAQPNLVDSAGF-KIDIEEVASSRPKGEV 536 Query 535 TGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVD 594 T+P G++ S + +QVS G++ MP L G+ A RLR GWTG + Sbjct 537 VATSPAGGSSADRGSTVTVQVSAGDEITMPTLVGLTPSQAVERLRQSGWTGNAGQINQAT 596 Query 595 AGGSQH---NRVVYQNPPAGTGVNRDGIITLRFG 625 G + R++ Q P AG+ +++ IT+ G Sbjct 597 TGTFEAGSVGRILQQQPQAGSSISKTATITITVG 630 >gi|226303517|ref|YP_002763475.1| serine/threonine protein kinase PknB [Rhodococcus erythropolis PR4] gi|226182632|dbj|BAH30736.1| probable serine/threonine protein kinase PknB [Rhodococcus erythropolis PR4] Length=641 Score = 618 bits (1593), Expect = 1e-174, Method: Compositional matrix adjust. Identities = 338/636 (54%), Positives = 426/636 (67%), Gaps = 13/636 (2%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP +LS RYELGEILGFGGMSEVHLARDLRL RDVA+KVLRADLARDP+FYLRFRREA Sbjct 1 MTTPRNLSSRYELGEILGFGGMSEVHLARDLRLSRDVAIKVLRADLARDPTFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET AGPLPYIVMEYVDG TLRDIV + GPMTP++A+EVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETDAGPLPYIVMEYVDGDTLRDIVRSTGPMTPRKAMEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH+NGI+HRDVKPANIMI+ AVKVMDFGIARAI+D+ + +TQTAAVIGTA Sbjct 121 DVCAALDFSHRNGIVHRDVKPANIMINRAGAVKVMDFGIARAISDASSPMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVL+E+LTGEPPF GDSPV+VAYQHVREDP PS + Sbjct 181 QYLSPEQARGEQVDARSDVYSLGCVLFEILTGEPPFKGDSPVAVAYQHVREDPQTPSEIN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + +LD+++LKA++KNP NRYQ+A +MR+DLVRV G+ P AP V+ D +RT++L + Sbjct 241 PDIPRELDSIILKAMSKNPANRYQSAGDMRSDLVRVLGGQRPSAPMVMNDEDRTTILGAV 300 Query 301 AGNLSGPRTDPLPRQDL-DDTDRDR---SIGSVGRWVAV-VAVLAVLTVVVTIAINTFGG 355 + RT P P + + T R + GR+ + +A L V+ +V I Sbjct 301 GSDTGNYRTAPDPVEPVPARTTRAAEPPAKKKGGRYALMGIAALLVIGLVTFFLIRVNSP 360 Query 356 ITRDVQVP-DVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGD 414 V VP D+ Q + A ATL N GF++ QK D I +VI T P A + G Sbjct 361 KVEMVTVPGDLTNQPADVAEATLTNAGFQVERQQKTDKVIAAGNVITTRPVAGVRIEKGS 420 Query 415 EITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQ--ANSPSTPELVGKVIGTNP 472 +T++VSTGPEQ IP ++ L+ +A KKL + G R + ST V K++ +P Sbjct 421 TVTIDVSTGPEQVAIPRLTGLSQDDAEKKLNSVGL-RLDPTIGKAASTIAEVDKIVNQDP 479 Query 473 PANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAG 532 + + + V I VG+GP +PDV GQ +VA+ N+ GF +DS P G Sbjct 480 AVGVSVVLDSAVSITVGTGPEQVRVPDVTGQREEVARPNIEGAGFV-VQITEIDSGLPKG 538 Query 533 EVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTG---MLDK 589 +V T+P GT+ S + L+VS GNQ MPDL+ +A LRA GW G L + Sbjct 539 QVVSTDPTGGTSATKGSTVTLRVSNGNQVAMPDLTNKTVSEALTTLRAAGWAGTASQLVQ 598 Query 590 GADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFG 625 ++V Q P G+ +++D +IT+ G Sbjct 599 NQSTTLTPEMVGKIVSQTQPPGSEISKDAVITVSVG 634 >gi|229491116|ref|ZP_04384944.1| serine/threonine-protein kinase PknB [Rhodococcus erythropolis SK121] gi|229321854|gb|EEN87647.1| serine/threonine-protein kinase PknB [Rhodococcus erythropolis SK121] Length=641 Score = 616 bits (1589), Expect = 3e-174, Method: Compositional matrix adjust. Identities = 337/636 (53%), Positives = 425/636 (67%), Gaps = 13/636 (2%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP +LS RYELGEILGFGGMSEVHLARDLRL RDVA+KVLRADLARDP+FYLRFRREA Sbjct 1 MTTPRNLSSRYELGEILGFGGMSEVHLARDLRLSRDVAIKVLRADLARDPTFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAET AGPLPYIVMEYVDG TLRDIV + GPM P++A+EVIA Sbjct 61 QNAAALNHPAIVAVYDTGEAETDAGPLPYIVMEYVDGDTLRDIVRSTGPMAPRKAMEVIA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH+NGI+HRDVKPANIMI+ AVKVMDFGIARAI+D+ + +TQTAAVIGTA Sbjct 121 DVCAALDFSHRNGIVHRDVKPANIMINRAGAVKVMDFGIARAISDASSPMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+ VDARSDVYSLGCVL+E+LTGEPPF GDSPV+VAYQHVREDP PS + Sbjct 181 QYLSPEQARGEQVDARSDVYSLGCVLFEILTGEPPFKGDSPVAVAYQHVREDPQTPSEIN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + +LD+++LKA++KNP NRYQ+A +MR+DLVRV G+ P AP V+ D +RT++L + Sbjct 241 PDIPRELDSIILKAMSKNPANRYQSAGDMRSDLVRVLGGQRPSAPMVMNDEDRTTILGAV 300 Query 301 AGNLSGPRTDPLPRQDL-DDTDRDR---SIGSVGRWVAV-VAVLAVLTVVVTIAINTFGG 355 + RT P P + + T R + GR+ + +A L V+ +V I Sbjct 301 GSDTGNYRTAPDPVEPVAARTTRAAEPPAKKKGGRYALMGIAALLVIGLVTFFLIRVNSP 360 Query 356 ITRDVQVP-DVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGD 414 V VP D+ Q + A ATL N GF++ QK D I +VI T P A + G Sbjct 361 KVEMVTVPGDLTNQPADVAEATLTNAGFQVERQQKTDKVIAAGNVITTRPVAGVRIEKGS 420 Query 415 EITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQ--ANSPSTPELVGKVIGTNP 472 +T++VSTGPEQ IP ++ L+ +A KKL + G R + ST V K++ +P Sbjct 421 TVTIDVSTGPEQVAIPRLTGLSQDDAEKKLNSVGL-RLDPTIGKAASTVAEVDKIVNQDP 479 Query 473 PANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAG 532 + + + V I VG+GP +PDV GQ +VA+ N+ GF +DS P G Sbjct 480 AVGVSVVLDSAVSITVGTGPEQVRVPDVTGQREEVARPNIEGAGFV-VQITEIDSGLPKG 538 Query 533 EVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTG---MLDK 589 +V T+P GT+ S + L+VS GNQ MPDL+ +A LRA GW G L + Sbjct 539 QVVSTDPTGGTSATKGSTVTLRVSNGNQVAMPDLTNRTVSEALSTLRAAGWAGTASQLVQ 598 Query 590 GADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFG 625 ++V Q P G+ +++D +IT+ G Sbjct 599 NQSTTLTPEMVGKIVSQTQPPGSEISKDAVITVSVG 634 >gi|28374107|pdb|1O6Y|A Chain A, Catalytic Domain Of Pknb Kinase From Mycobacterium Tuberculosis gi|112490636|pdb|2FUM|A Chain A, Catalytic Domain Of Protein Kinase Pknb From Mycobacterium Tuberculosis In Complex With Mitoxantrone gi|112490637|pdb|2FUM|B Chain B, Catalytic Domain Of Protein Kinase Pknb From Mycobacterium Tuberculosis In Complex With Mitoxantrone gi|112490638|pdb|2FUM|C Chain C, Catalytic Domain Of Protein Kinase Pknb From Mycobacterium Tuberculosis In Complex With Mitoxantrone gi|112490639|pdb|2FUM|D Chain D, Catalytic Domain Of Protein Kinase Pknb From Mycobacterium Tuberculosis In Complex With Mitoxantrone Length=299 Score = 573 bits (1478), Expect = 2e-161, Method: Compositional matrix adjust. Identities = 279/279 (100%), Positives = 279/279 (100%), Gaps = 0/279 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 21 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 80 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA Sbjct 81 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 140 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA Sbjct 141 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 200 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH Sbjct 201 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 260 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNG 279 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNG Sbjct 261 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNG 299 >gi|333917710|ref|YP_004491291.1| serine/threonine-protein kinase PknB [Amycolicicoccus subflavus DQS3-9A1] gi|333479931|gb|AEF38491.1| Serine/threonine-protein kinase PknB [Amycolicicoccus subflavus DQS3-9A1] Length=626 Score = 573 bits (1476), Expect = 4e-161, Method: Compositional matrix adjust. Identities = 324/636 (51%), Positives = 414/636 (66%), Gaps = 25/636 (3%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 M TP LS RYELGE +GFGGMSEVHLARD RL RDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MITPRQLSGRYELGETIGFGGMSEVHLARDHRLQRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALN+ IVAVYDTGEA T AGPLPYIVMEYVDG TLRDIV GPMTP +A+EVI+ Sbjct 61 QNAAALNNSTIVAVYDTGEAHTEAGPLPYIVMEYVDGDTLRDIVRLNGPMTPMKAMEVIS 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL FSH GI+HRDVKPANIMIS + A+KVMDFGIARAI+DS N++TQTA VIGTA Sbjct 121 DVCTALEFSHSKGIVHRDVKPANIMISRSGAIKVMDFGIARAISDSTNTITQTATVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 YLSPEQARG+ V RSD+YSLGCVLYE+ TG+PPFTGDSPV+VAYQHV+EDP+PPS Sbjct 181 HYLSPEQARGEKVGPRSDIYSLGCVLYELATGQPPFTGDSPVAVAYQHVKEDPLPPSQID 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSL--LS 298 + +LDA++LKA++KNP NRYQTAAEM++DL R +G+ P AP V+TD ERT++ +S Sbjct 241 PRVPRELDAIILKAISKNPANRYQTAAEMQSDLRRAIDGQKPSAPSVMTDEERTTIIGIS 300 Query 299 SAAGNLSGPRTDPLPRQDLDDTDR---DRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGG 355 S G+ + P+P D+ R RSI V + + +T + Sbjct 301 SVPGDEA-----PMPTADVYPRGRRLVRRSILLVLLVALLASAAFAVTWMRRDDAVVMVM 355 Query 356 ITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDE 415 + V++ SSA+A + L GF + T + D ++P +VIGTDP + T V+ G + Sbjct 356 VPSVVRL------SSAEAQSELGQLGFDVYTEFRADLSVPEGNVIGTDPPSGTQVTQGSQ 409 Query 416 ITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQ----ANSPSTPELVGKVIGTN 471 +TV+VSTGP + +PD++ LT EA L AG + A+S + +L VI N Sbjct 410 VTVHVSTGPGRVPVPDIAQLTMDEARDALEDAGLELAEDIERVASSAADADL---VIRQN 466 Query 472 PPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPA 531 P + + + V + +G+GP IPDV GQ V +A+ NL+ GF +DS PA Sbjct 467 PSSGVSVTVGTAVRVTIGTGPELVRIPDVTGQNVVIAEANLSAAGFA-VDIDEIDSDEPA 525 Query 532 GEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTG-MLDKG 590 G V +P GT S++ ++VS G Q MP+L G +A LR+ GWTG L + Sbjct 526 GTVATMSPQGGTQAVSGSIVTIRVSNGAQLTMPNLVGRRPSEALDLLRSAGWTGDGLAES 585 Query 591 ADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 ++ R+V Q AG+ + R I + G+ Sbjct 586 TRATLNPAEVGRIVSQQQSAGSTIRRGDTIAVEVGE 621 >gi|262200069|ref|YP_003271277.1| serine/threonine protein kinase-like protein [Gordonia bronchialis DSM 43247] gi|262083416|gb|ACY19384.1| Serine/threonine protein kinase-related protein [Gordonia bronchialis DSM 43247] Length=635 Score = 567 bits (1462), Expect = 2e-159, Method: Compositional matrix adjust. Identities = 315/629 (51%), Positives = 411/629 (66%), Gaps = 4/629 (0%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 M+TP HLSDRYELGE LGFGGMSEVH ARDL LHRDVAVKVLRADLARDPSFYLRFRREA Sbjct 2 MSTPHHLSDRYELGETLGFGGMSEVHYARDLLLHRDVAVKVLRADLARDPSFYLRFRREA 61 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAA LNHP IV V+DTGEAET GPLP+IVMEYV+G TLRDI+ GP+ P++A+ +A Sbjct 62 QNAAKLNHPTIVQVFDTGEAETDEGPLPFIVMEYVEGETLRDILRANGPVAPRQAMTWMA 121 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D A++FSH+NGI+HRD+KPAN+MI + AVKVMDFGIARA++D+ ++TQT+AV+GTA Sbjct 122 DVAAAMDFSHRNGIVHRDMKPANVMIDKSGAVKVMDFGIARAMSDTSATMTQTSAVMGTA 181 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG VD RSD+YS+GCVL+E+LTGEPPFTGDSPV+VA+QHV EDP PS Sbjct 182 QYLSPEQARGIKVDPRSDIYSMGCVLFELLTGEPPFTGDSPVAVAHQHVHEDPPWPSHVK 241 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + +LD+VVLKA++KN +NRYQ+AA++RADL++V G P AP +L+D ERT + + Sbjct 242 PEIPRELDSVVLKAMSKNKDNRYQSAADLRADLIKVLAGGKPSAPLLLSDEERTEFIDTG 301 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 T R++ D + R + AV AVL +L V+ R V Sbjct 302 PRKAMRADTGGTHRREDGDAEPPRRRSRKLMFGAVAAVLLLLAVLFVFWAPWSSDSARQV 361 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSA-GDEITVN 419 VPDV G S+ DA A L GF+++ L +P +TI H T P + ++A G E+T+ Sbjct 362 AVPDVAGLSAQDAQAALTKAGFQVKILDEPSTTIDAGHATHTAPGGDNVLAAEGSEVTLY 421 Query 420 VSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSA 479 +S+GP + +IPDV T EAV L GF K ST EL KV+ T P Sbjct 422 ISSGPPREKIPDVRGQTQDEAVASLNRLGFTNVKAVRVDSTAELKDKVVETAPMIGMEVP 481 Query 480 ITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNP 539 ++ VV + +G+GP +P++ GQT + A+ L + + VDS PAG++ ++P Sbjct 482 VSGVVELRIGNGPKVVTVPNLVGQTQEQARIYLEQIQL-RMAVVQVDSDLPAGQIVSSSP 540 Query 540 PAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTG--MLDKGADVDAGG 597 AG V SV+++ VS+GN FVMP+L G A L GW G + +V Sbjct 541 NAGQEVDEGSVVQVSVSRGNMFVMPNLDGQTPAQASAALSRRGWQGTTLTQSPRNVPLVS 600 Query 598 SQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 +VV Q+P G+ V +DG I++ GQ Sbjct 601 PDGGKVVDQDPAPGSKVRKDGAISIVVGQ 629 >gi|343928761|ref|ZP_08768206.1| serine/threonine protein kinase PknB [Gordonia alkanivorans NBRC 16433] gi|343761510|dbj|GAA15132.1| serine/threonine protein kinase PknB [Gordonia alkanivorans NBRC 16433] Length=649 Score = 564 bits (1453), Expect = 2e-158, Method: Compositional matrix adjust. Identities = 313/645 (49%), Positives = 414/645 (65%), Gaps = 21/645 (3%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HLSDRYELGE LGFGGMSEVH ARDL LHRDVA+KVLRADLARDPSFYLRFRREA Sbjct 1 MTTPHHLSDRYELGETLGFGGMSEVHYARDLVLHRDVAIKVLRADLARDPSFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAA LNHP IV V+DTGEAET GPLP+IVMEYVDG TLRD++ GP+ P++A+ +A Sbjct 61 QNAAKLNHPTIVQVFDTGEAETEDGPLPFIVMEYVDGDTLRDVLRANGPIAPRQAMTWMA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D A++FSH+NGI+HRD+KPAN+MI + AVKVMDFGIARA++DS +++TQT+AV+GTA Sbjct 121 DVAAAMDFSHRNGIVHRDMKPANVMIDKSGAVKVMDFGIARAMSDSTSTMTQTSAVMGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG VD RSD+YS+GCVL+E+LTGEPPFTGDSPV+VA+QHV EDP PS Sbjct 181 QYLSPEQARGIKVDPRSDIYSMGCVLFELLTGEPPFTGDSPVAVAHQHVHEDPPWPSHVR 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + +LD++VLKA++KN +NRYQ+AA++RADL+RV G P AP +LTD ERT + + Sbjct 241 PDIPRELDSIVLKAMSKNKDNRYQSAADLRADLIRVLAGGKPSAPMLLTDEERTEFIDTG 300 Query 301 -----AGNLSGPRTDPLP-------RQDLDDTDRDRSIGSVGRWVAVV--AVLAVLTVVV 346 +GPR +P R+D D R ++ A+ AV+ +V Sbjct 301 PRRPVRSETTGPRR-AIPARAGGSHRRDADYRSDSDDDPPRRRSRRLMAGAIAAVVLLVG 359 Query 347 TIAINT--FGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDP 404 T+ + + G DV VP V G SS DA + L+ GF++R L++P + P + P Sbjct 360 TLFLWSPWSSGSDPDVSVPAVAGLSSEDAQSALERAGFEVRVLEEPSLDVGPGLATRSTP 419 Query 405 AANTSVSAGDEITVNVSTGPEQREIP-DVSTLTYAEAVKKLTAAGFGRFKQANSPSTPEL 463 + G E+ + +STGP++ IP D+ T AEA+ L GF K ST ++ Sbjct 420 GEGVLAAEGSEVALYISTGPQRHRIPSDLVGKTPAEALDALKVLGFTNVKTERVDSTVDM 479 Query 464 VGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQA 523 KV+ T P + V++ VG+GP + DV G D A+ L G T + Sbjct 480 KDKVVSTAPKIGTEVPVNGPVVLNVGNGPREITVRDVIGMPADRARAVLEELGMT-VDEV 538 Query 524 SVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGW 583 +VDS + AGEV T+P G+T S +++ VS+GN F +P L G +A+ L GW Sbjct 539 AVDSDQRAGEVLSTSPGPGSTAEQGSTVQISVSRGNLFTVPSLRGKTPAEAQASLEQAGW 598 Query 584 --TGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 + + + +V + RVV Q PPAG+ + G +T+ GQ Sbjct 599 ERSTLTRQTRNVPLNSPDNGRVVGQEPPAGSKARKSGAVTIIIGQ 643 >gi|326383933|ref|ZP_08205617.1| serine/threonine protein kinase-like protein [Gordonia neofelifaecis NRRL B-59395] gi|326197392|gb|EGD54582.1| serine/threonine protein kinase-like protein [Gordonia neofelifaecis NRRL B-59395] Length=635 Score = 560 bits (1443), Expect = 3e-157, Method: Compositional matrix adjust. Identities = 301/631 (48%), Positives = 419/631 (67%), Gaps = 12/631 (1%) Query 4 PSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNA 63 P +LS+RYELGE LGFGGMSEV ARDL LHRDVA+KVLRADLARDP+FYLRFRREAQNA Sbjct 3 PHYLSERYELGETLGFGGMSEVQFARDLLLHRDVAIKVLRADLARDPTFYLRFRREAQNA 62 Query 64 AALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADAC 123 A LNHP+IV V+DTGEA+T GPLP+IVMEYV+G TLRD++ + G + K+A+ +AD Sbjct 63 AKLNHPSIVQVFDTGEADTDEGPLPFIVMEYVEGETLRDVLRSSGHIAQKQAMTWMADVA 122 Query 124 QALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYL 183 A++FSH+N I+HRD+KPAN+MI T AVKVMDFGIARA+ D+ ++TQT+AV+GTAQYL Sbjct 123 AAMDFSHRNNIVHRDMKPANVMIDRTGAVKVMDFGIARAMDDTSATMTQTSAVMGTAQYL 182 Query 184 SPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGL 243 SPEQARG VD RSD+YS+GCVL+E++TGEPPFTGDSP++VA+QHV EDP PS+ + Sbjct 183 SPEQARGIKVDPRSDIYSMGCVLFELVTGEPPFTGDSPIAVAHQHVHEDPRRPSSIRPEI 242 Query 244 SADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSAAGN 303 + +LD+V++KA++KNP NRYQTAAE RADL++V G P AP +LTD E+T+L+ S Sbjct 243 TPELDSVIMKAMSKNPANRYQTAAEFRADLIKVLAGGKPSAPMLLTDEEQTALIDSPRLA 302 Query 304 LSGPRTDPLP-RQDLDDTDRDRSIGS----VGRWVAVVAVLAVLTVVVTI-AINTFGGIT 357 + R + LP R D D + S G+ R +A+ AV+ +++ + A + + Sbjct 303 V---RNESLPSRGDGGDEEEPPSDGNGFLRRRRVQVTIAIAAVIVLLIGLFAWSPWKTTA 359 Query 358 RDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEIT 417 + VP V G ++ A A L+ GF ++ Q+ + I T P + G E+T Sbjct 360 PLIAVPKVAGLAADAAQANLEQAGFTVKQSQEASADIARGLATRTAPGDDVPTPKGSEVT 419 Query 418 VNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQT 477 + +S+GP++++IPD+ T EA K L GF K + ST L KV+ TNP Sbjct 420 LYISSGPQRQQIPDLRGRTADEATKALNVLGFNDVKTQEAESTVALKDKVVRTNPRTGIP 479 Query 478 SAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGT 537 +A+ VI+ +G+GP +PD+ GQT D A+K L+ + + VDS PAG+V T Sbjct 480 AAVNAAVILYIGTGPKEVTLPDLRGQTSDQARKTLDQLQL-EMTTVQVDSELPAGQVVST 538 Query 538 NPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGG 597 +P G TV V S I++Q+S+GN F++PDL G DA+ L GW ++ G Sbjct 539 SPNPGATVEVGSTIQVQISRGNMFIVPDLRGKSLEDAQKALEDAGWQPNTLSSSERGVGL 598 Query 598 SQHN--RVVYQNPPAGTGVNRDGIITLRFGQ 626 + + +V+ Q+PPAG+ + +D +++ G+ Sbjct 599 ASKDDGKVIAQSPPAGSKLRKDATVSVVVGR 629 Score = 61.2 bits (147), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 50/206 (25%), Positives = 101/206 (50%), Gaps = 11/206 (5%) Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIP-PDHVIGTDPAANTSVSAGDEITVN 419 Q+PD+RG+++ +A L GF Q+ +ST+ D V+ T+P + + + Sbjct 430 QIPDLRGRTADEATKALNVLGFNDVKTQEAESTVALKDKVVRTNPRTGIPAAVNAAVILY 489 Query 420 VSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPEL-VGKVIGTNPPANQTS 478 + TGP++ +PD+ T +A K L + + EL G+V+ T+P T Sbjct 490 IGTGPKEVTLPDLRGQTSDQARKTLDQL---QLEMTTVQVDSELPAGQVVSTSPNPGATV 546 Query 479 AITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVD-----SPRPAGE 533 + + + + + G +PD+ G++++ AQK L G+ + +S + + + G+ Sbjct 547 EVGSTIQVQISRGNMFI-VPDLRGKSLEDAQKALEDAGWQPNTLSSSERGVGLASKDDGK 605 Query 534 VTGTNPPAGTTVPVDSVIELQVSKGN 559 V +PPAG+ + D+ + + V + + Sbjct 606 VIAQSPPAGSKLRKDATVSVVVGRAS 631 >gi|331694005|ref|YP_004330244.1| serine/threonine protein kinase with PASTA sensor(s) [Pseudonocardia dioxanivorans CB1190] gi|326948694|gb|AEA22391.1| serine/threonine protein kinase with PASTA sensor(s) [Pseudonocardia dioxanivorans CB1190] Length=643 Score = 557 bits (1435), Expect = 3e-156, Method: Compositional matrix adjust. Identities = 314/637 (50%), Positives = 411/637 (65%), Gaps = 16/637 (2%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP LS+RYELG+ LG+GGMSEVH D RL RDVAVKVLRADLARDP F LRFRREA Sbjct 1 MTTPRLLSERYELGDTLGYGGMSEVHRGLDTRLGRDVAVKVLRADLARDPQFQLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGE + GPLPYIVME+VDG TLR+IV T+GP+ R ++V+A Sbjct 61 QNAAALNHPAIVAVYDTGETTSEFGPLPYIVMEFVDGHTLREIVKTQGPLDQGRVLDVMA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH++ IIHRDVKPANIMI+ AVKVMDFGIARA+ + G +VTQTAAVIGTA Sbjct 121 DVCAALDFSHRHNIIHRDVKPANIMINTAGAVKVMDFGIARALGE-GQNVTQTAAVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG++VDARSDVY+ GCVL+E+LTG+PPFTGD+PV+VAYQHVREDP PSA + Sbjct 180 QYLSPEQARGEAVDARSDVYAAGCVLFELLTGDPPFTGDTPVAVAYQHVREDPRHPSALN 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + +LDA+VLKAL+KNP NRYQ+AAEMRADL+RV NG+ P+AP V++D ERT+LL++ Sbjct 240 PAVPPELDAIVLKALSKNPANRYQSAAEMRADLIRVRNGQRPQAPLVMSDDERTALLAAN 299 Query 301 AGN----LSGPRTDPLPRQDLDDTDRDRSIGSVGRWVA-VVAVLAVLTVVVTIAINTFGG 355 A + + G LP + + GR +A VV ++AVL ++ +A FGG Sbjct 300 ATSPTRRIGGAGRHTLPPDAVPAWRDEEPPPRTGRKIAIVVGIVAVLALIAFVAYQFFGG 359 Query 356 --ITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAG 413 + V VPDV GQ A + N G + Q + + V+ TDPA NT ++ Sbjct 360 PPSPKQVTVPDVVGQQQEAARTAVINAGLRADIEQTASTPDQVNKVVKTDPAGNTQIAEN 419 Query 414 DEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSP-STPELVGKVIGTNP 472 + + + +GP Q +P + L+ ++A +L G +Q S P +VGK+I +NP Sbjct 420 STVKIFIGSGPAQSAVPPIVGLSVSDAQAQLQERGLTLGQQTEQETSDPSMVGKIISSNP 479 Query 473 PANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAG 532 + V ++VG P+ +PDV GQ D A+ L GF Q Sbjct 480 APGTNADAGTPVAVVVGKQPSNVSVPDVTGQDADSARSALTKAGFQVQVQGDTSG---DA 536 Query 533 EVTGTNPPAGTTVPVDSVIELQV---SKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDK 589 VTG NP AGT V + + + + + GNQ MP+L GM A+ ++ G T + + Sbjct 537 VVTGMNPSAGTKVAKGTTVTITMGSSNSGNQVQMPNLVGMDVASAQAAVQQAGLTNVRRQ 596 Query 590 GADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 V+ SQ ++ Q PAG +++D +T+ GQ Sbjct 597 NVPVN-DRSQDGKIQQQTVPAGQQIDKDQQVTVLVGQ 632 >gi|302531406|ref|ZP_07283748.1| serine/threonine protein kinase [Streptomyces sp. AA4] gi|302440301|gb|EFL12117.1| serine/threonine protein kinase [Streptomyces sp. AA4] Length=664 Score = 548 bits (1412), Expect = 1e-153, Method: Compositional matrix adjust. Identities = 318/645 (50%), Positives = 407/645 (64%), Gaps = 36/645 (5%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP LS+RYELG+ LG+GGMSEVH D+RL R+VA+KVLRADLARDP F RFRREA Sbjct 1 MTTPRLLSNRYELGDTLGYGGMSEVHHGHDVRLGREVAIKVLRADLARDPQFQERFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEA T GPLPYIVMEYV+G TLRDIV TEGP++ KRA+EV+A Sbjct 61 QNAAALNHPAIVAVYDTGEANTDVGPLPYIVMEYVEGRTLRDIVKTEGPLSQKRAMEVMA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH++GI+HRDVKPAN+MI+ AVKVMDFGIARA+ D +++TQTAAVIGTA Sbjct 121 DVCAALDFSHRHGIVHRDVKPANVMITKNGAVKVMDFGIARAMHDGQSAMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+SVDARSDVY+ GCVLYE++TGEPPFTGDSPV+VAYQHVREDP PPS+ + Sbjct 181 QYLSPEQARGESVDARSDVYAAGCVLYELITGEPPFTGDSPVAVAYQHVREDPNPPSSVN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 +S +LDAVVLKALAK P NRYQ+AAEMR+DLVR +G+ P AP V++D ERT ++++ Sbjct 241 PAVSPELDAVVLKALAKGPANRYQSAAEMRSDLVRTLSGQRPSAPMVMSDDERTQVMNAD 300 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRD- 359 R P + D + R + + A+L V + I G RD Sbjct 301 -------RRQPQAYDEYADEPEEDPRAKRRRRIIFGLIAALLVAGVVLLIFWLNGAFRDK 353 Query 360 ---VQVPDVRGQSSADAIATLQNRGFKIRTLQK-----PDSTIPP---------DHVIGT 402 Q+P V +A A+LQ GF K P+++ P VI Sbjct 354 AENAQIPQVINHQLVEAKASLQQAGFSSFAPNKEVVCGPEASNPGGLTCTEDQIGKVIAI 413 Query 403 DPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPS--- 459 DP SV IT+ V P +PD+ + +A L A + K N+ S Sbjct 414 DPPVGQSVPTTSTITLTVGKQPGTTTVPDLRGKSPDDAKAALDQA---KLKLGNTTSQPV 470 Query 460 -TPELVGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFT 518 P VGKV+ NP AN S V I+VGSG +++P+ G+ A++ + GF Sbjct 471 DNPSDVGKVVSQNPTANSQSPEGTPVDIVVGSGLTQREVPNTVGKDYATAKQIIQNAGF- 529 Query 519 KFSQASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKG-NQFVMPDLSGMFWVDAEPR 577 K + S +P +V P G +P +S ++L VS G Q MPDL+GM A + Sbjct 530 KPQRVDQASDQPKDQVIEQQPNGG-NLPPNSPVKLIVSTGPQQIQMPDLTGMTQDQATRQ 588 Query 578 LRALGWTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITL 622 L++LGW+G + + +G + N VV QNP AG+ ++ + I L Sbjct 589 LQSLGWSGSI-QTQSTSSGSGKPNTVVKQNPQAGSQISPNQTIVL 632 >gi|294662208|pdb|2KUI|A Chain A, Nmr Structure Of The Pasta Domain Of Mycobacterium Tuberculo Pknb Length=275 Score = 548 bits (1411), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 272/272 (100%), Positives = 272/272 (100%), Gaps = 0/272 (0%) Query 355 GITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGD 414 GITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGD Sbjct 4 GITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGD 63 Query 415 EITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPA 474 EITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPA Sbjct 64 EITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPA 123 Query 475 NQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEV 534 NQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEV Sbjct 124 NQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEV 183 Query 535 TGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVD 594 TGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVD Sbjct 184 TGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVD 243 Query 595 AGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 AGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ Sbjct 244 AGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 275 Score = 46.2 bits (108), Expect = 0.016, Method: Compositional matrix adjust. Identities = 45/137 (33%), Positives = 67/137 (49%), Gaps = 6/137 (4%) Query 340 AVLTVVVTIAINTFGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHV 399 + +T VV I + + G T+D+ PDV GQ+ A L GF + DS P V Sbjct 127 SAITNVVIIIVGS-GPATKDI--PDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEV 183 Query 400 IGTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRF--KQANS 457 GT+P A T+V I + VS G Q +PD+S + + +A +L A G+ K A+ Sbjct 184 TGTNPPAGTTVPVDSVIELQVSKG-NQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADV 242 Query 458 PSTPELVGKVIGTNPPA 474 + +V+ NPPA Sbjct 243 DAGGSQHNRVVYQNPPA 259 >gi|134096662|ref|YP_001102323.1| serine/threonine protein kinase [Saccharopolyspora erythraea NRRL 2338] gi|291009312|ref|ZP_06567285.1| serine/threonine protein kinase [Saccharopolyspora erythraea NRRL 2338] gi|133909285|emb|CAL99397.1| serine/threonine protein kinase [Saccharopolyspora erythraea NRRL 2338] Length=653 Score = 547 bits (1410), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 311/642 (49%), Positives = 416/642 (65%), Gaps = 23/642 (3%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 M++P LS+RYE+G+ LG+GGMSEVH RD+RL RDVAVKVLRADLARDP+F LRFRREA Sbjct 1 MSSPRLLSNRYEIGDTLGYGGMSEVHRGRDIRLGRDVAVKVLRADLARDPTFQLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGE ++ GPLPYIVMEYVDG TLRDIV +EGP+ P+RA+EV+A Sbjct 61 QNAAALNHPAIVAVYDTGETDSENGPLPYIVMEYVDGRTLRDIVKSEGPLAPRRAMEVMA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 DA AL+FSH++ IIHRDVKPANIMI+ + AVKVMDFGIARA+ D +VTQTAAVIGTA Sbjct 121 DASAALDFSHRHHIIHRDVKPANIMITRSGAVKVMDFGIARALTDGQAAVTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+SVDARSDVY+ GCVL+E+LTGEPPFTGDSPV+VAYQHVREDP PS + Sbjct 181 QYLSPEQARGESVDARSDVYASGCVLFELLTGEPPFTGDSPVAVAYQHVREDPRKPSDVN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + + A LDAVVLKAL+KNP NRYQ+AAEMRADLVRV +G+ P+AP ++++ ERTS+++ A Sbjct 241 QQVPASLDAVVLKALSKNPANRYQSAAEMRADLVRVLSGQRPKAPMIMSEEERTSMIAPA 300 Query 301 -AGNLSGP-----RTDPLPRQDLD-DTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTF 353 A + P +P DLD + R R + V ++ V AV +V +A Sbjct 301 PATEVMAPGGRHRSVEPAVEDDLDAEQQRKRRKNWLIALVTLICV-AVFALVAWVANALL 359 Query 354 GGITRD--VQVPDVRGQSSADAIATLQNRGFKIR-TLQKPDSTIPPDHVIGTDPAANTSV 410 G + D + VP + G + + A++ L + + + P S VI P + Sbjct 360 SGPSGDDKIAVPQLEGMTKSQALSELTAGNWLWQEQIPCPSSREDVGRVINQTPDPGVPI 419 Query 411 -SAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPEL-----V 464 D I V TGPEQ +IPD+ ++ +A KL+ G +P T E+ V Sbjct 420 DKKQDRIRVCFGTGPEQVQIPDLRGMSMDQASAKLSEVG---LMLGYNPKTREVDNDSQV 476 Query 465 GKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQAS 524 K++ +P T A + +++G + +PDV + A++ L+ GF + ++ Sbjct 477 DKILEWDPEG--TVAKGTTINVVLGKKAEQRAVPDVRNMPYETAERMLSYAGF-QVQRSD 533 Query 525 VDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWT 584 DS PAG V P A T + S + + VS G Q MP L+G+ DA+ +L+ LGW Sbjct 534 RDSSEPAGIVVDQTPAADTKLKPGSKVTVYVSNGQQISMPPLTGLSPTDAKRQLQQLGWN 593 Query 585 GMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 G L + + + +V+ +P G ++++ IT+ G+ Sbjct 594 GQLVEQKESTSDSKLDGKVMRSSPSGGDKISKNQTITIYVGE 635 >gi|300781986|ref|YP_003762277.1| serine/threonine protein kinase [Amycolatopsis mediterranei U32] gi|299791500|gb|ADJ41875.1| serine/threonine protein kinase [Amycolatopsis mediterranei U32] gi|340523341|gb|AEK38546.1| serine/threonine protein kinase [Amycolatopsis mediterranei S699] Length=658 Score = 547 bits (1410), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 315/648 (49%), Positives = 406/648 (63%), Gaps = 29/648 (4%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 M+TP LS+RYELGE LG+GGMSEVH D+RL R+VA+K+LRADLARDP F RFRREA Sbjct 1 MSTPRLLSNRYELGETLGYGGMSEVHHGHDVRLGREVAIKILRADLARDPQFLERFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAAALNHPAIVAVYDTGEA GPLPYIVMEYV+G TLRDIV TEGPM+ KRA+EV+A Sbjct 61 QNAAALNHPAIVAVYDTGEANAEFGPLPYIVMEYVEGRTLRDIVKTEGPMSQKRAMEVMA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH++GI+HRDVKPAN+MI+ AVKVMDFGIARA+ D +++TQTAAVIGTA Sbjct 121 DVCAALDFSHRHGIVHRDVKPANVMITKNGAVKVMDFGIARAMHDGQSAMTQTAAVIGTA 180 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+SVDARSDVY+ GCVLYE++TGEPPFTGDSPV+VAYQHVREDP PS+ + Sbjct 181 QYLSPEQARGESVDARSDVYAAGCVLYELITGEPPFTGDSPVAVAYQHVREDPSAPSSVN 240 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 ++ +LDAVVLKALAK P NRYQ+AAEMR+DLVR +G+ P AP V+++ ERT +++ Sbjct 241 PAVAPELDAVVLKALAKGPANRYQSAAEMRSDLVRTLSGQRPVAPMVMSEDERTQVMN-- 298 Query 301 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAINTFGGITRDV 360 A R D D +D R ++ VA V VL + +++ ++ V Sbjct 299 ADRRQPQRYDEYSEPDDEDPKAKRRRRAILAAVAAVFVLGAVLLIMWLSNAFKSNDPTTV 358 Query 361 QVPDVRGQSSADAIATLQNRGFKIRTLQK-------PDSTIPP------DHVIGTDPAAN 407 VPDV Q+ A TL ++GF QK P P + VI DP Sbjct 359 AVPDVLHQTVPQARETLISKGFTGTVEQKQVTCGVQPTDGNPQCGQDDVNRVIKIDPGVG 418 Query 408 TSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGF---GRFKQANSPSTPELV 464 T V++ ++T+ V P + +PD+ T +A + LT A G Q S P Sbjct 419 TQVASTQKMTLYVGVAPGKSSVPDLKGKTRDQAEQALTDAKLTLDGSV-QETEVSDPNQA 477 Query 465 GKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFT--KFSQ 522 G V+ NPP+ V I +G K + D Q A+ +L GFT + Q Sbjct 478 GLVLAQNPPSGSQVDQGTSVKITIGKSKQLKTVTDFTNQAYSKAKSSLESQGFTTKRVDQ 537 Query 523 ASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKG----NQFVMPDLSGMFWVDAEPRL 578 AS P+ + T P G + V S I L VS G +Q MP L+GM A+ +L Sbjct 538 ASETVPK---DTVITQNPNGGQLAVGSQIVLTVSTGPDSSSQIQMPLLAGMTLDQAQDKL 594 Query 579 RALGWTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRFGQ 626 ++GWTG ++ +D ++ + + QNP AGT +NRD +T+ + Sbjct 595 SSMGWTGKFNQKSDKNSNAPE-GTITGQNPSAGTMINRDQNVTVNVSE 641 Score = 76.3 bits (186), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/210 (30%), Positives = 108/210 (52%), Gaps = 14/210 (6%) Query 362 VPDVRGQSSADAIATLQNRGFKIR-TLQKPDSTIPPDH--VIGTDPAANTSVSAGDEITV 418 VPD++G++ A L + + ++Q+ + + P V+ +P + + V G + + Sbjct 440 VPDLKGKTRDQAEQALTDAKLTLDGSVQETEVSDPNQAGLVLAQNPPSGSQVDQGTSVKI 499 Query 419 NVSTGPEQREIPDVSTLTYAEAVKKLTAAGF--GRFKQANSPSTPELVGKVIGTNPPANQ 476 + + + + D + Y++A L + GF R QA S + P+ VI NP Q Sbjct 500 TIGKSKQLKTVTDFTNQAYSKAKSSLESQGFTTKRVDQA-SETVPK--DTVITQNPNGGQ 556 Query 477 TSAITNVVIIIVGSGPATK---DIPDVAGQTVDVAQKNLNVYGFT-KFSQAS-VDSPRPA 531 A+ + +++ V +GP + +P +AG T+D AQ L+ G+T KF+Q S +S P Sbjct 557 L-AVGSQIVLTVSTGPDSSSQIQMPLLAGMTLDQAQDKLSSMGWTGKFNQKSDKNSNAPE 615 Query 532 GEVTGTNPPAGTTVPVDSVIELQVSKGNQF 561 G +TG NP AGT + D + + VS+GN F Sbjct 616 GTITGQNPSAGTMINRDQNVTVNVSEGNGF 645 >gi|296137777|ref|YP_003645020.1| serine/threonine protein kinase with PASTA sensor(s) [Tsukamurella paurometabola DSM 20162] gi|296025911|gb|ADG76681.1| serine/threonine protein kinase with PASTA sensor(s) [Tsukamurella paurometabola DSM 20162] Length=664 Score = 541 bits (1393), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 313/668 (47%), Positives = 404/668 (61%), Gaps = 54/668 (8%) Query 1 MTTP-SHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRRE 59 MTTP ++DRY+LGE LGFGGMSEVHLARD RL RDVA+K+LRADLARDPSFY RFRRE Sbjct 1 MTTPPRRINDRYDLGETLGFGGMSEVHLARDTRLSRDVAIKILRADLARDPSFYERFRRE 60 Query 60 AQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVI 119 AQNAA+LNHP IV VYDTGEA+TP GPLPYIVMEYVDG TLRD++ +G + P+ A+ + Sbjct 61 AQNAASLNHPTIVQVYDTGEADTPGGPLPYIVMEYVDGETLRDVLRRDGTIAPQAAMTWM 120 Query 120 ADACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGT 179 AD C AL+FSH+NGI+HRD+KPAN+M++ T +KVMDFGIARA++D +TQTAAVIGT Sbjct 121 ADVCAALDFSHRNGIVHRDMKPANVMLTRTGEIKVMDFGIARAMSDPSAGMTQTAAVIGT 180 Query 180 AQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSAR 239 AQYLSPEQARG+SVDARSDVY+ GCVL+E+LTG+PPF GDSPVSVAYQHVREDP PS+ Sbjct 181 AQYLSPEQARGESVDARSDVYAAGCVLFELLTGQPPFQGDSPVSVAYQHVREDPPTPSSI 240 Query 240 HEGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSS 299 + + +LD++ LKAL+KNP NRYQTA EMR DL+RV G PEAP VL+D ER +LL+ Sbjct 241 LDTVPPELDSITLKALSKNPANRYQTAGEMRQDLIRVLAGRKPEAPMVLSDEERDALLTE 300 Query 300 AAGNLSGPRTDP-------------------LPRQDLDDTDR---------------DRS 325 + PR P + D DR S Sbjct 301 P----TKPRRAAKAAPAAAAAAAAVPAAAAGTPGEPTGDDDRPTEAVATVPAASGRAKHS 356 Query 326 IGSVGR-----WVAVVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQSSADAIATLQNR 380 S GR W++ + +L T + + V VP GQ+++DA LQ Sbjct 357 TASGGRSRLVLWISAAIIAIILVGGTTAYLLAGPDEAKQVTVPSQIGQNASDAQVALQKL 416 Query 381 GFKIRTLQKPDSTIPPDHVIGTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEA 440 GF ++ + PD+T+P + VI T P ++ + G + V VS+GP+ +PDV + +A Sbjct 417 GFNVQIKRVPDNTVPAEQVISTIPGPDSQATEGSTVIVEVSSGPKIAAVPDVVNRSEKDA 476 Query 441 VKKLTAAGFGRFKQANSPSTPEL-VGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPD 499 LT AGF K ++P + G V+ TNP + +++ V +G +PD Sbjct 477 RDILTKAGFTVAKDPKKEASPTVKAGDVVSTNPAVGANTPQNTPIVLTVSTGKEQVRVPD 536 Query 500 VAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGN 559 V+ + A+ NL GFT Q VD P PAG V T P GTT S I + VSK Sbjct 537 VSNTALSQAEANLKGLGFTTKVQ-EVDDPAPAGTVLRTTPAGGTTADKGSDITIVVSKAK 595 Query 560 QFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH-----NRVVYQNPPAGTGV 614 VMP+L G A+ L A+G++ + V A + N+V P AG V Sbjct 596 AVVMPNLVGQDPSAAKAALIAMGFS---ESNIQVMATAPSNLPWDKNKVWKTTPDAGARV 652 Query 615 NRDGIITL 622 + IT+ Sbjct 653 DTSASITI 660 >gi|325000787|ref|ZP_08121899.1| serine/threonine protein kinase [Pseudonocardia sp. P1] Length=661 Score = 540 bits (1392), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 324/638 (51%), Positives = 401/638 (63%), Gaps = 29/638 (4%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP LS+RYELG+ LG+GGMSEVH D RL RDVAVKVLRADLARDP F LRFRREA Sbjct 1 MTTPRLLSERYELGDPLGYGGMSEVHRGLDTRLGRDVAVKVLRADLARDPQFQLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QN+A+LNHPAIVAVYDTGE E+ GPLPYIVME+VDG TLR+IV T GP++ +R +EV+A Sbjct 61 QNSASLNHPAIVAVYDTGEIESEFGPLPYIVMEFVDGQTLREIVKTTGPLSQQRVVEVMA 120 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D C AL+FSH++GIIHRDVKPAN+MI+ AVKVMDFGIARA+ + G +VTQTAAVIGTA Sbjct 121 DVCAALDFSHRHGIIHRDVKPANVMINGVGAVKVMDFGIARALGE-GQNVTQTAAVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG+SVDARSDVY+ GCVL+E+LTGEPPFTGD+PV+VAYQHVREDP PS + Sbjct 180 QYLSPEQARGESVDARSDVYAAGCVLFELLTGEPPFTGDTPVAVAYQHVREDPRAPSELN 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSS- 299 + LDAVVLKAL+KNP NRYQ+AAEMRADLVRV NGEP AP V+++ ERT +++ Sbjct 240 PSVPPALDAVVLKALSKNPANRYQSAAEMRADLVRVRNGEPVHAPLVMSEYERTQMMAHD 299 Query 300 ----------AAGN-LSGPRTDPL---PRQDLDDTDRDRSIG-SVGRWVAVVAVLAVLTV 344 AGN GP T P D D D R G + W+ + VL +L Sbjct 300 DATTAMPTRRMAGNGAGGPPTGRHVMPPDHDGYDDDSGRGRGKKIALWLVGLIVLGLLGF 359 Query 345 VVTIAINTFGGITRD-VQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVIGTD 403 V F + D V VPDV GQ+ A +T+ G +P V+ TD Sbjct 360 V---GFQMFSNSSPDQVSVPDVLGQTPEQARSTISAVGLLPDQQNQPSDVAQIGKVVRTD 416 Query 404 PAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGF---GRFKQANSPST 460 P V+ +TV V TGP + +P + + ++A +L AG G +Q S S+ Sbjct 417 PGGGNQVAENSRVTVFVGTGPAEVTVPSLVGSSPSDAEVQLREAGLQVGGTTEQETSDSS 476 Query 461 PELVGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKF 520 +GK+I T+P Q V ++VG T +PDV GQ+ + A L GFT Sbjct 477 --QIGKIIRTDPGPGQRVPGNTSVALVVGKEQTTVSVPDVTGQSAEQAANTLRGAGFTSV 534 Query 521 SQASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRA 580 S VD AG V GT+P AGT V D I +QVS+GNQ +P++ G +A LR Sbjct 535 STTEVDGGGSAGSVVGTDPAAGTRVQKDRAISIQVSRGNQSQIPNVVGQRVDNAVNTLRE 594 Query 581 LGWTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDG 618 G + + VD S N +V P+G DG Sbjct 595 AGLSFQIQT---VDVSDSSQNGIVLNQSPSGGSQASDG 629 Score = 63.9 bits (154), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 63/209 (31%), Positives = 100/209 (48%), Gaps = 13/209 (6%) Query 421 STGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGKVIGTNPPANQTSAI 480 ++ P+Q +PDV T +A ++A G Q N PS +GKV+ T+P A Sbjct 367 NSSPDQVSVPDVLGQTPEQARSTISAVGL-LPDQQNQPSDVAQIGKVVRTDPGGGNQVAE 425 Query 481 TNVVIIIVGSGPATKDIPDVAGQT-----VDVAQKNLNVYGFTKFSQASVDSPRPAGEVT 535 + V + VG+GPA +P + G + V + + L V G T+ Q + DS + G++ Sbjct 426 NSRVTVFVGTGPAEVTVPSLVGSSPSDAEVQLREAGLQVGGTTE--QETSDSSQ-IGKII 482 Query 536 GTNPPAGTTVPVDSVIELQVSKGNQFV-MPDLSGMFWVDAEPRLRALGWTGMLDKGADVD 594 T+P G VP ++ + L V K V +PD++G A LR G+T + D Sbjct 483 RTDPGPGQRVPGNTSVALVVGKEQTTVSVPDVTGQSAEQAANTLRGAGFTSVSTTEVDGG 542 Query 595 AGGSQHNRVVYQNPPAGTGVNRDGIITLR 623 VV +P AGT V +D I+++ Sbjct 543 G---SAGSVVGTDPAAGTRVQKDRAISIQ 568 >gi|317507736|ref|ZP_07965441.1| protein kinase [Segniliparus rugosus ATCC BAA-974] gi|316253989|gb|EFV13354.1| protein kinase [Segniliparus rugosus ATCC BAA-974] Length=635 Score = 532 bits (1371), Expect = 7e-149, Method: Compositional matrix adjust. Identities = 302/635 (48%), Positives = 394/635 (63%), Gaps = 19/635 (2%) Query 1 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREA 60 MTTP HL RY LGE +G+GGMSEVH+ARD RL R+VA+K+LR DLARDP FYLRFRREA Sbjct 1 MTTPKHLGGRYALGEAIGYGGMSEVHIARDERLGREVAIKLLRPDLARDPRFYLRFRREA 60 Query 61 QNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIA 120 QNAA+LNHP IV+V+DTGE+ + GP+PYIVMEYVDG TLR+ + GP+T ++ + IA Sbjct 61 QNAASLNHPMIVSVFDTGESASDQGPMPYIVMEYVDGQTLREALQN-GPLTTEQVLSWIA 119 Query 121 DACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIADSGNSVTQTAAVIGTA 180 D AL+FSHQNGI+HRDVKP NIMI VKVMDFGIARAI+DS + TQTA VIGTA Sbjct 120 DVASALDFSHQNGIVHRDVKPGNIMIDKLGQVKVMDFGIARAISDSTITATQTATVIGTA 179 Query 181 QYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARH 240 QYLSPEQARG++VD RSDVYSLGCVLYE+L G PPFTGD+P+S+AYQHVREDP PPS+ + Sbjct 180 QYLSPEQARGETVDPRSDVYSLGCVLYELLAGAPPFTGDTPLSIAYQHVREDPKPPSSLN 239 Query 241 EGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA 300 + LS D+DAVVLK+++KNP NRYQTAAE+R+DLV++ GE P AP+V+++AER SLLS+ Sbjct 240 KALSPDIDAVVLKSMSKNPANRYQTAAELRSDLVKLLAGERPSAPRVMSEAERQSLLST- 298 Query 301 AGNLSGPRTDPLPRQDLDDTD-RDRSIGSVGRWVAVVAVLAVLTVVVTIAI-NTFGGITR 358 G ++GP + PL + R R G + A+ + V V AI N G Sbjct 299 -GEITGPTSKPLRAHGQPVAEPRPRPKGV---YAALSIAVVVAIVAAYFAIHNVIKGQPN 354 Query 359 DVQVPDVRGQSSADAIATLQNRGFK---IRTLQKPDSTIPPDHVIGTDPAANTSVSAGDE 415 + +P+V G S A +L G I+ + D+ V GT P++ ++V E Sbjct 355 YIMIPNVVGMSEQQATDSLSKAGVSKSHIKIERTEDTQAKKGSVTGTVPSSGSTVDKNVE 414 Query 416 ITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFGRFKQANSPSTPELVGK--VIGTNPP 473 +T+ VS GP Q ++PD+ + +A L AG A V K VIGT P Sbjct 415 VTLTVSAGPGQTKVPDLRGKSIGDATVLLAEAGLNVDPNAPPAEYSNEVDKDRVIGTRPE 474 Query 474 ANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGE 533 A + A + V +++ G T +P+V G + A K L G + S P G+ Sbjct 475 AGKAVAKGSKVQLVISKGSETIQVPNVVGAQSEAAAKTLTDAGLAQPRSEEQSSTEPYGK 534 Query 534 VTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADV 593 V +P G+ I L +SKG+QFVMPDL+GM +A LR G G + + Sbjct 535 VLNQSPQPGSEAKRGDTITLTISKGDQFVMPDLTGMTEAEARDALRKAGLVGTPTRQSTQ 594 Query 594 DAG------GSQHNRVVYQNPPAGTGVNRDGIITL 622 G +V Q+P GT + G +T+ Sbjct 595 GNGLLFPDPNKVPGQVFRQDPAPGTAFPKLGTVTI 629 Lambda K H 0.315 0.132 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1438247500800 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40