BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0035 Length=562 Score E Sequences producing significant alignments: (Bits) Value gi|15839412|ref|NP_334449.1| AMP-binding family protein [Mycobac... 1148 0.0 gi|253796950|ref|YP_003029951.1| fatty-acid-CoA ligase fadD34 [M... 1145 0.0 gi|289747804|ref|ZP_06507182.1| fatty-acid-CoA ligase fadD34 [My... 1144 0.0 gi|289572611|ref|ZP_06452838.1| fatty-acid-CoA ligase fadD34 [My... 1144 0.0 gi|289760132|ref|ZP_06519510.1| fatty-acid-CoA ligase [Mycobacte... 1144 0.0 gi|306778856|ref|ZP_07417193.1| fatty-acid-CoA ligase fadD34 [My... 1141 0.0 gi|340625068|ref|YP_004743520.1| putative fatty-acid-CoA ligase ... 1135 0.0 gi|289567921|ref|ZP_06448148.1| fatty-acid-CoA ligase fadD34 [My... 972 0.0 gi|289748500|ref|ZP_06507878.1| fatty-acid-CoA ligase fadD34 [My... 876 0.0 gi|254548968|ref|ZP_05139415.1| fatty-acid-CoA ligase fadD34 [My... 721 0.0 gi|254548967|ref|ZP_05139414.1| putative fatty-acid-CoA ligase [... 382 9e-104 gi|56478676|ref|YP_160265.1| CoA ligase, AMP generating (three f... 236 8e-60 gi|307726757|ref|YP_003909970.1| AMP-dependent synthetase and li... 231 2e-58 gi|297161053|gb|ADI10765.1| acyl-CoA synthetase [Streptomyces bi... 224 4e-56 gi|257095448|ref|YP_003169089.1| AMP-dependent synthetase and li... 222 2e-55 gi|295681464|ref|YP_003610038.1| AMP-dependent synthetase and li... 219 7e-55 gi|162455335|ref|YP_001617702.1| acyl-CoA synthetase [Sorangium ... 219 9e-55 gi|209515271|ref|ZP_03264138.1| AMP-dependent synthetase and lig... 218 2e-54 gi|335419445|ref|ZP_08550497.1| AMP-dependent synthetase and lig... 216 8e-54 gi|115378536|ref|ZP_01465692.1| saframycin Mx1 synthetase B [Sti... 214 3e-53 gi|215919292|ref|NP_820905.2| acyl-CoA synthetase [Coxiella burn... 214 4e-53 gi|161830319|ref|YP_001597743.1| acyltransferase family protein ... 213 5e-53 gi|296160928|ref|ZP_06843740.1| AMP-dependent synthetase and lig... 212 2e-52 gi|238024664|ref|YP_002908896.1| Saframycin Mx1 synthetase [Burk... 211 3e-52 gi|186471740|ref|YP_001863058.1| AMP-dependent synthetase and li... 211 4e-52 gi|300311697|ref|YP_003775789.1| acyltransferase family protein ... 210 6e-52 gi|162450802|ref|YP_001613169.1| acyl-CoA synthetase [Sorangium ... 209 1e-51 gi|91789248|ref|YP_550200.1| AMP-dependent synthetase and ligase... 209 1e-51 gi|209363707|ref|YP_001423619.2| acyl-CoA synthetase [Coxiella b... 209 1e-51 gi|212211705|ref|YP_002302641.1| acyl-CoA synthetase [Coxiella b... 209 1e-51 gi|212217721|ref|YP_002304508.1| acyl-CoA synthetase [Coxiella b... 209 1e-51 gi|165918760|ref|ZP_02218846.1| acyltransferase family protein [... 209 1e-51 gi|153206239|ref|ZP_01945502.1| acyltransferase family protein [... 209 1e-51 gi|288941226|ref|YP_003443466.1| 1-acyl-sn-glycerol-3-phosphate ... 209 2e-51 gi|224824125|ref|ZP_03697233.1| AMP-dependent synthetase and lig... 208 2e-51 gi|344341519|ref|ZP_08772438.1| AMP-dependent synthetase and lig... 207 4e-51 gi|167567182|ref|ZP_02360098.1| AMP-binding domain protein [Burk... 207 5e-51 gi|89900929|ref|YP_523400.1| AMP-dependent synthetase and ligase... 207 6e-51 gi|121595383|ref|YP_987279.1| AMP-dependent synthetase and ligas... 206 6e-51 gi|167572594|ref|ZP_02365468.1| AMP-binding domain protein [Burk... 206 1e-50 gi|296170910|ref|ZP_06852447.1| AMP-binding protein [Mycobacteri... 204 3e-50 gi|71068219|gb|AAZ23074.1| acyl-CoA ligase [Streptomyces fradiae] 204 3e-50 gi|82701365|ref|YP_410931.1| acyl-CoA synthetase [Nitrosospira m... 204 4e-50 gi|52842442|ref|YP_096241.1| saframycin Mx1 synthetase B [Legion... 204 4e-50 gi|182678861|ref|YP_001833007.1| AMP-dependent synthetase and li... 203 5e-50 gi|296445080|ref|ZP_06887041.1| AMP-dependent synthetase and lig... 202 1e-49 gi|86740633|ref|YP_481033.1| AMP-dependent synthetase and ligase... 201 2e-49 gi|112791733|gb|ABI22131.1| putative non-ribosomal peptide synth... 201 3e-49 gi|54301694|ref|YP_131687.1| acyltransferase family protein [Pho... 200 5e-49 gi|320353995|ref|YP_004195334.1| AMP-dependent synthetase and li... 200 5e-49 >gi|15839412|ref|NP_334449.1| AMP-binding family protein [Mycobacterium tuberculosis CDC1551] gi|31791212|ref|NP_853705.1| fatty-acid-CoA ligase [Mycobacterium bovis AF2122/97] gi|57116683|ref|YP_177686.1| fatty-acid-CoA ligase [Mycobacterium tuberculosis H37Rv] 33 more sequence titles Length=562 Score = 1148 bits (2969), Expect = 0.0, Method: Compositional matrix adjust. Identities = 562/562 (100%), Positives = 562/562 (100%), Gaps = 0/562 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS Sbjct 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 Query 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT Sbjct 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 Query 541 HAWTADPDSAPKTTRSSLEGAH 562 HAWTADPDSAPKTTRSSLEGAH Sbjct 541 HAWTADPDSAPKTTRSSLEGAH 562 >gi|253796950|ref|YP_003029951.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis KZN 1435] gi|289552284|ref|ZP_06441494.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis KZN 605] gi|297632506|ref|ZP_06950286.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis KZN 4207] 6 more sequence titles Length=562 Score = 1145 bits (2961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/562 (99%), Positives = 561/562 (99%), Gaps = 0/562 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTL DDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLHDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS Sbjct 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 Query 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT Sbjct 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 Query 541 HAWTADPDSAPKTTRSSLEGAH 562 HAWTADPDSAPKTTRSSLEGAH Sbjct 541 HAWTADPDSAPKTTRSSLEGAH 562 >gi|289747804|ref|ZP_06507182.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis 02_1987] gi|298527433|ref|ZP_07014842.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis 94_M4241A] gi|289688332|gb|EFD55820.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis 02_1987] gi|298497227|gb|EFI32521.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis 94_M4241A] Length=562 Score = 1144 bits (2960), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/562 (99%), Positives = 561/562 (99%), Gaps = 0/562 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQI ACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQIWACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS Sbjct 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 Query 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT Sbjct 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 Query 541 HAWTADPDSAPKTTRSSLEGAH 562 HAWTADPDSAPKTTRSSLEGAH Sbjct 541 HAWTADPDSAPKTTRSSLEGAH 562 >gi|289572611|ref|ZP_06452838.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis K85] gi|289537042|gb|EFD41620.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis K85] Length=562 Score = 1144 bits (2959), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/562 (99%), Positives = 561/562 (99%), Gaps = 0/562 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLR LDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRCLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS Sbjct 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 Query 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT Sbjct 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 Query 541 HAWTADPDSAPKTTRSSLEGAH 562 HAWTADPDSAPKTTRSSLEGAH Sbjct 541 HAWTADPDSAPKTTRSSLEGAH 562 >gi|289760132|ref|ZP_06519510.1| fatty-acid-CoA ligase [Mycobacterium tuberculosis T85] gi|294995649|ref|ZP_06801340.1| putative fatty-acid-CoA ligase [Mycobacterium tuberculosis 210] gi|289715696|gb|EFD79708.1| fatty-acid-CoA ligase [Mycobacterium tuberculosis T85] gi|326905796|gb|EGE52729.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis W-148] gi|339293112|gb|AEJ45223.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis CCDC5079] gi|339296760|gb|AEJ48870.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis CCDC5180] Length=562 Score = 1144 bits (2958), Expect = 0.0, Method: Compositional matrix adjust. Identities = 560/562 (99%), Positives = 561/562 (99%), Gaps = 0/562 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQI ACTDRTLTI+CEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQIWACTDRTLTISCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS Sbjct 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 Query 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT Sbjct 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 Query 541 HAWTADPDSAPKTTRSSLEGAH 562 HAWTADPDSAPKTTRSSLEGAH Sbjct 541 HAWTADPDSAPKTTRSSLEGAH 562 >gi|306778856|ref|ZP_07417193.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis SUMu002] gi|306782646|ref|ZP_07420968.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis SUMu003] gi|306787012|ref|ZP_07425334.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis SUMu004] 13 more sequence titles Length=569 Score = 1141 bits (2951), Expect = 0.0, Method: Compositional matrix adjust. Identities = 562/569 (99%), Positives = 562/569 (99%), Gaps = 7/569 (1%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPL-------LRHHRVL 113 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPL LRHHRVL Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLMTRLGPLLRHHRVL 120 Query 114 ICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAY 173 ICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAY Sbjct 121 ICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAY 180 Query 174 VQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAAL 233 VQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAAL Sbjct 181 VQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAAL 240 Query 234 FNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLH 293 FNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLH Sbjct 241 FNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLH 300 Query 294 KMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTET 353 KMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTET Sbjct 301 KMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTET 360 Query 354 HAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDT 413 HAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDT Sbjct 361 HAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDT 420 Query 414 HDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVV 473 HDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVV Sbjct 421 HDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVV 480 Query 474 LESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDG 533 LESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDG Sbjct 481 LESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDG 540 Query 534 TLPRLATHAWTADPDSAPKTTRSSLEGAH 562 TLPRLATHAWTADPDSAPKTTRSSLEGAH Sbjct 541 TLPRLATHAWTADPDSAPKTTRSSLEGAH 569 >gi|340625068|ref|YP_004743520.1| putative fatty-acid-CoA ligase FADD34 [Mycobacterium canettii CIPT 140010059] gi|340003258|emb|CCC42375.1| putative fatty-acid-CoA ligase FADD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) [Mycobacterium canettii CIPT 140010059] Length=562 Score = 1135 bits (2935), Expect = 0.0, Method: Compositional matrix adjust. Identities = 557/562 (99%), Positives = 559/562 (99%), Gaps = 0/562 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCE SEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEHSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDS 480 DDEIVILGRQDEVFIV+GENRFPYDIEFIIR ESEQHRTKVACFGVNERVVVVLES LDS Sbjct 421 DDEIVILGRQDEVFIVYGENRFPYDIEFIIRRESEQHRTKVACFGVNERVVVVLESQLDS 480 Query 481 IIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 IID+AEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT Sbjct 481 IIDEAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 Query 541 HAWTADPDSAPKTTRSSLEGAH 562 HAWTADPDSAPKTTRSSLEGAH Sbjct 541 HAWTADPDSAPKTTRSSLEGAH 562 >gi|289567921|ref|ZP_06448148.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis T17] gi|289541674|gb|EFD45323.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis T17] Length=475 Score = 972 bits (2512), Expect = 0.0, Method: Compositional matrix adjust. Identities = 473/473 (100%), Positives = 473/473 (100%), Gaps = 0/473 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 3 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 62 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 63 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 122 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 123 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 182 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 183 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 242 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 243 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 302 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 303 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 362 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 363 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 422 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVV 473 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVV Sbjct 423 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVV 475 >gi|289748500|ref|ZP_06507878.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis T92] gi|289689087|gb|EFD56516.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis T92] Length=503 Score = 876 bits (2264), Expect = 0.0, Method: Compositional matrix adjust. Identities = 430/430 (100%), Positives = 430/430 (100%), Gaps = 0/430 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV Sbjct 181 TAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAV 240 Query 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII Sbjct 241 FTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLII 300 Query 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV Sbjct 301 ASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV 360 Query 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV Sbjct 361 TGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 Query 421 DDEIVILGRQ 430 DDEIVILGRQ Sbjct 421 DDEIVILGRQ 430 >gi|254548968|ref|ZP_05139415.1| fatty-acid-CoA ligase fadD34 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=354 Score = 721 bits (1862), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/354 (100%), Positives = 354/354 (100%), Gaps = 0/354 (0%) Query 209 HGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFM 268 HGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFM Sbjct 1 HGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFM 60 Query 269 PNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALG 328 PNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALG Sbjct 61 PNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALG 120 Query 329 SGYGLAEATVAVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRG 388 SGYGLAEATVAVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRG Sbjct 121 SGYGLAEATVAVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRG 180 Query 389 DSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEF 448 DSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEF Sbjct 181 DSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEF 240 Query 449 IIRGESEQHRTKVACFGVNERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITV 508 IIRGESEQHRTKVACFGVNERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITV Sbjct 241 IIRGESEQHRTKVACFGVNERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITV 300 Query 509 RRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAWTADPDSAPKTTRSSLEGAH 562 RRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAWTADPDSAPKTTRSSLEGAH Sbjct 301 RRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAWTADPDSAPKTTRSSLEGAH 354 >gi|254548967|ref|ZP_05139414.1| putative fatty-acid-CoA ligase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=186 Score = 382 bits (981), Expect = 9e-104, Method: Compositional matrix adjust. Identities = 186/186 (100%), Positives = 186/186 (100%), Gaps = 0/186 (0%) Query 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV Sbjct 1 MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPV 60 Query 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH Sbjct 61 LITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEH 120 Query 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS Sbjct 121 DEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGS 180 Query 181 TAAPRG 186 TAAPRG Sbjct 181 TAAPRG 186 >gi|56478676|ref|YP_160265.1| CoA ligase, AMP generating (three fragments in different reading frames) [Aromatoleum aromaticum EbN1] gi|56314719|emb|CAI09364.1| CoA ligase, AMP generating (three fragments in different reading frames) [Aromatoleum aromaticum EbN1] Length=831 Score = 236 bits (602), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 182/571 (32%), Positives = 266/571 (47%), Gaps = 54/571 (9%) Query 2 TAALLSPAIAWQQISACTDRTLTI-------TCEDSEVISYQDLIARAAACIPPLRRLDL 54 +AA L A+ WQ + DR + + E + Y L A A L R + Sbjct 44 SAADLVEALQWQ-VGRNPDRDHVLFYRGDAEQAGEPERLGYAALAADATRIAGGLVRRGV 102 Query 55 KRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLI 114 + V + + L+F CF G++ GA+PVP+ P E + R +LR+ + Sbjct 103 VPDQCVALMLPSGLDFFRCFFGVLFAGAIPVPMYPPARASQIEDHLRRQAGILRNCEAPV 162 Query 115 CTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYV 174 +R + TA++LAD A PL + A V Sbjct 163 LVAFMRPLLRVLGGLAPSLRHIV-------------TAEELADAPDAT-PLPARSEAALV 208 Query 175 QYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALF 234 QYTSGST P+GV +++ NLL+N+RA DV SWLPL+HDMGL+G+ +L+ Sbjct 209 QYTSGSTGDPKGVTLSHANLLANIRAYGRVLNVSSTDVCVSWLPLYHDMGLIGAWLGSLY 268 Query 235 NSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHK 294 ++ V +P FL P +L + T T PNFA E + R D+ G+DL Sbjct 269 HACPLVLMSPLDFLARPECWLWAIHRHRGTITAAPNFAFELCVKRLGDR--DLAGLDLAS 326 Query 295 MRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTE-- 352 + + +EPV A + RFA F GL L YGLAE ++A++M+ P G RT+ Sbjct 327 WQIAMNGAEPVSAGTLERFADAFGRYGLRREILAPVYGLAECSLALTMTPPGRGMRTDRI 386 Query 353 -----THA-----------AAEVVTGGRVLPGYEVRIDAA-----PGARAGTIKLRGDSV 391 THA + +VV+ G LPG+EVRI A P R G ++ RG S Sbjct 387 ERAAMTHAGRRSPAGGDTPSVDVVSCGLPLPGHEVRIVGADGRMLPERRIGQLEFRGPSA 446 Query 392 AAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIR 451 A + AL +G+ DT D +LVD E+ + GR ++ I G N +PY++E + Sbjct 447 TAGYFRNPAADAALFHDGWLDTGDFAYLVDGELYVTGRAKDMIIRGGRNFYPYELEQAVG 506 Query 452 GESEQHRTKVACFGV------NERVVVVLE-SPLDSIIDKAEADRLRCQVVAATGLQLDE 504 + VA FGV ER+VVV E D+ +A R+ GL DE Sbjct 507 ELPGVRKGCVAAFGVPDAAPAGERLVVVAEMREKDAAARQALEQRIVAVSSDVLGLPADE 566 Query 505 LITVRRGAIPTTTSGKLKRRAVAQAYRDGTL 535 ++ V A+ T+SGK++R A+ + YR GTL Sbjct 567 VVLVPPHAVLKTSSGKIRRGAIREGYRHGTL 597 >gi|307726757|ref|YP_003909970.1| AMP-dependent synthetase and ligase [Burkholderia sp. CCGE1003] gi|307587282|gb|ADN60679.1| AMP-dependent synthetase and ligase [Burkholderia sp. CCGE1003] Length=947 Score = 231 bits (590), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 181/563 (33%), Positives = 267/563 (48%), Gaps = 55/563 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPI- 87 S ++Y L A LRRL + G+ V + T ++ +CF G++L GA+ VP+ Sbjct 145 SSHTMTYAALYEAAQRVSGALRRLGVNPGDTVAMMLPTGSDYFACFAGILLIGAIVVPVY 204 Query 88 PPREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQF 147 PP ++ + + ++R +L R + H ++ A A Q Sbjct 205 PPAQSARINDH-LSRQAAILSDARARVMIVPSH----------ALVASLLAKARVPTLQE 253 Query 148 GRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQF 207 A AQ + +T + + +D A +QYTSGST AP+GVV+++ NLL+N+RAM +Q Sbjct 254 IVAPAQLMGETDNERY-VPRAEDAALLQYTSGSTGAPKGVVLSHANLLANLRAMGQTAQI 312 Query 208 QHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTF 267 GD+ SWLPL+HDMGL+G+ F L+ + + +P FL P +L+ ++ AT T Sbjct 313 GEGDIFASWLPLYHDMGLIGAWFGPLYYGIPLILMSPLTFLARPARWLQAVSHYRATITA 372 Query 268 MPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTAL 327 PNFA E AD+EGIDL +R +EPV A MR FAA FA G + AL Sbjct 373 APNFAYERCTRRIEE--ADLEGIDLSSLRLAFCGAEPVSASTMRAFAARFANYGFSKNAL 430 Query 328 GSGYGLAEATVAVSMSAPNTGFRTETHAAA------------------EVVTGGRVLPGY 369 YGLAE T+ ++ S P G RT+ + A E+V+ GR LP Sbjct 431 NPVYGLAENTLGLTFSEPGRGVRTDCISRARLSDSQRATPAESPDDVLELVSCGRALPHN 490 Query 370 EVRIDAAPGARA-----GTIKLRGDSVAAKAYVGGKKLDA-LDEEGFCDTHDLGFLVDDE 423 EVRI G G I+ R S A + Y L A L G+ DT DLG++ ++E Sbjct 491 EVRIVDVSGNEVSERTIGRIEFRSPS-ATRGYFLNPGLTAQLIHNGWLDTGDLGYMAEEE 549 Query 424 IVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVLES- 476 + I GR ++ I G + FPY++E + VA G +R++V+ E+ Sbjct 550 LFITGRVKDLVIRAGRHFFPYELEASVGRLRGVRSGCVAVCGAPDIERGTDRLIVIAETR 609 Query 477 -PLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAY---RD 532 + +AD + VA G +E+ V +I T+SGK++ A Q Y R Sbjct 610 ETAPEALATMQAD-INAASVALLGTPPEEVALVPPHSILKTSSGKIRHAATLQLYLASRG 668 Query 533 GTLPRLATHAWTADPDSAPKTTR 555 PR W D A T R Sbjct 669 NLSPRAPWLQWL---DIAANTVR 688 >gi|297161053|gb|ADI10765.1| acyl-CoA synthetase [Streptomyces bingchenggensis BCW-1] Length=497 Score = 224 bits (571), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 173/503 (35%), Positives = 241/503 (48%), Gaps = 64/503 (12%) Query 69 EFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAE--HDEIRAA 126 EF+ F+G++ G +PVP+ P L E + RL H C P DE Sbjct 7 EFIVAFIGMVSAGVIPVPVFPPAMLTRIEAYRERL-----HSIHSSCEPRHIIADESLFD 61 Query 127 ASTDCQISRFTALAE-AGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPR 185 D ++ AE A E G + + PL ++QYTSGSTA P+ Sbjct 62 ICVDAVGTKPIGYAELAAGEPTGELVEAEGGE------PL-------FLQYTSGSTAMPK 108 Query 186 GVVITYRNLLSNMRAM--AVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTT 243 GVV+T+ NLL N RAM A+G+ + D SWLPL+HDMGL+G + L V F Sbjct 109 GVVVTHDNLLENARAMDQALGTSGER-DRFVSWLPLYHDMGLIGCMLGPLVYEVPVWFIP 167 Query 244 PHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGAD--IEGIDLHKMRRLIIA 301 P+ F P +L ++ T ++ PNFA E + RR D + G DL R + Sbjct 168 PYEFARRPTTWLDWMSKISGTFSYAPNFAYELVT----RRATDKQMAGWDLSAWRGAGVG 223 Query 302 SEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRT---------- 351 +EPV MR FA FAGVG A+ YGLAE T+ V+ + G RT Sbjct 224 AEPVRPRTMREFAERFAGVGFDANAITPSYGLAEGTLGVAFTTIGDGLRTLSVDRAAFEE 283 Query 352 -------------ETHAAAEVVTGGRVLPGYEVRIDAAPGARA-----GTIKLRGDSVAA 393 E E+V+ G +L G+E RI AA G A G I++RG SV A Sbjct 284 EGAVRPVEPGAGAEATGTREIVSCGPLLSGWEARIRAASGEPADESTEGQIEIRGGSV-A 342 Query 394 KAYVGGKKL-DALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRG 452 + Y G ++L + +G+ T DLGFL D E+ + GR ++ I HG P DIE+ G Sbjct 343 RGYWGARELSEETFRDGWLRTGDLGFLRDGELYVTGRTKDLVIHHGRKYHPTDIEWSALG 402 Query 453 ESEQHRTKVACFGV-NERVVVVLE-SPLDSIIDKAEADRLRCQVVAATGLQLDELITVRR 510 V F +ER+VVV E P S D A+ ++ +V + G+ D+++ V+ Sbjct 403 LPGVRPDHVIAFSTPDERLVVVAEHKPASSPPDLAK--QIATRVRGSVGVTPDDVVLVKP 460 Query 511 GAIPTTTSGKLKRRAVAQAYRDG 533 G +P T+SGKL+R A AY G Sbjct 461 GTLPKTSSGKLRRAACRDAYSQG 483 >gi|257095448|ref|YP_003169089.1| AMP-dependent synthetase and ligase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gi|257047972|gb|ACV37160.1| AMP-dependent synthetase and ligase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length=944 Score = 222 bits (565), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 176/547 (33%), Positives = 256/547 (47%), Gaps = 64/547 (11%) Query 30 SEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPP 89 +E ISY +L+ ++ L L + V + T ++L+ F G+ML G +PVPI P Sbjct 154 AEAISYAELLEQSRRVATSLVTRGLLPRQAVALMLPTGRDYLTSFFGVMLAGGIPVPIYP 213 Query 90 REALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGR 149 L E L RH R+L A A T Q AL R Sbjct 214 PARLAQLEDH------LRRHARILANAEA------AFIITVPQAKGVAALL--------R 253 Query 150 ATAQQLADTATA----DWPLCTL-----DDDAYVQYTSGSTAAPRGVVITYRNLLSNMRA 200 A A L + T P+ L D A++QYTSGST P+GVV+T+ NLL+N+RA Sbjct 254 AEAPSLTEVLTPAELDSEPIGLLYRAAPADIAFLQYTSGSTGEPKGVVLTHANLLANLRA 313 Query 201 MAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTS 260 M DV SWLPL+HDMGL+G+ F +L+ + V +P FL P+ +LR ++ Sbjct 314 MGEAVAVTSDDVFVSWLPLYHDMGLIGAWFGSLYFGMRLVLMSPLAFLSRPVRWLRAISH 373 Query 261 SGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGV 320 T + PNFA + + A AD++G+DL R + +EPV ++ FA FA Sbjct 374 HRGTLSPAPNFAYD--LCARKLADADLQGLDLSSWRLALNGAEPVSPLTLQAFAERFAPY 431 Query 321 GLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVV-------------------T 361 GL P AL YGLAE +V ++ G R + A +V Sbjct 432 GLHPEALTPVYGLAECSVGLAFPPLGRGPRVDRVQRAALVGRKHARSADSGDTDALCVPA 491 Query 362 GGRVLPGYEVRI-----DAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDL 416 GRVLPG+E+R+ P G ++ RG S A Y AL +G+ D+ D Sbjct 492 CGRVLPGHEIRVVDEQNGELPDRYVGRLQFRGPSATAGYYRNPVATQALFRDGWLDSGDF 551 Query 417 GFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVN------ERV 470 + VD EI + GR ++ I G N +PY++E + R VA F N ER+ Sbjct 552 AYTVDGEIYLTGRVKDLIIRGGRNLYPYELEQAVGSIPGVRRGCVAVFASNDPVNATERL 611 Query 471 VVVLESPLDSIIDKAEADRLRCQ--VVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQ 528 VV+ E+ + D+ E R + VAA G+ DE++ ++ T+SGK++R A Sbjct 612 VVMAET-REEDADRREILRQKINEAAVAAVGMPADEVVLAPPNSVLKTSSGKIRRSASRD 670 Query 529 AYRDGTL 535 A+ G + Sbjct 671 AFEHGLI 677 >gi|295681464|ref|YP_003610038.1| AMP-dependent synthetase and ligase [Burkholderia sp. CCGE1002] gi|295441359|gb|ADG20527.1| AMP-dependent synthetase and ligase [Burkholderia sp. CCGE1002] Length=556 Score = 219 bits (559), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 169/551 (31%), Positives = 258/551 (47%), Gaps = 70/551 (12%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 D Y+ L A L L L +GE + + F+ FLG G VPVPI Sbjct 28 DEHYYPYEALEREARKRAQKLVSLGLNKGERIALVILDPEAFILSFLGASFAGLVPVPIF 87 Query 89 PREAL--KTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGD 144 PR +L +T ER+ + ++R R+L+ + + + I + D + R + D Sbjct 88 PRGSLNFRTRERYAETVSHIVRSAGARMLLTSNSTRETIEDVLAADTGLERIVTVEALLD 147 Query 145 EQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAM--A 202 + D P DD ++QYTSGST+ P+GV++T+RNL++N A Sbjct 148 -----------GEPPACDLPTLHPDDLCFLQYTSGSTSLPKGVMVTHRNLIANATAFLGP 196 Query 203 VGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSG 262 G DV SWLPLHHDMGL+ S+ AL + +V + F+ P ++ +T Sbjct 197 RGIDLHEQDVYVSWLPLHHDMGLI-SVLGALICDLPSVLLSTEAFVRRPGLWMEAITKYR 255 Query 263 ATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGL 322 T +F PNFA + + A R D+EG+DL ++R +EP++A+ +R+F+A F G Sbjct 256 GTISFAPNFA--YALAARRTRDQDLEGLDLSRLRVAGCGAEPINAQALRQFSARFEPAGF 313 Query 323 APTALGSGYGLAEATVAVSM------------------------SAPNTGFRTETHAAAE 358 AL YG+AEAT+A++ +A +TG RT E Sbjct 314 RAEALLPCYGMAEATLAITFHDHGQPIVTDVVYAAPLGLGRAIPAAHDTGLRT-----IE 368 Query 359 VVTGGRVLPGYEVRI-----DAAPGARAGTIKLRGDSVAAKAY-VGGKKLDALDEEGFCD 412 +V G PG+++RI P G I RG S+ A Y + DA +G+ Sbjct 369 LVGCGHCFPGHDLRIVDESGRGLPERCVGEIVTRGPSITAGYYGLADASADAY-RDGWLQ 427 Query 413 THDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV----NE 468 T DLG++ D++ I GR ++ ++HG N +P DIE+ + V F V +E Sbjct 428 TGDLGYVAGDQLYICGRSKDLIVIHGSNLYPQDIEWAVAELPSVQSRGVIAFSVMRDGDE 487 Query 469 RVVVVLESPLDSIIDKAEADRLR----CQVVAATGLQLDELITVRRGAIPTTTSGKLKRR 524 +VV E AEA LR +V GLQ+ + V+ G++P T+SGK++RR Sbjct 488 TLVVCAEG------KPAEATALRRAIAQKVAECAGLQVGHVAIVQAGSLPRTSSGKVQRR 541 Query 525 AVAQAYRDGTL 535 + G L Sbjct 542 RTKAQFEAGEL 552 >gi|162455335|ref|YP_001617702.1| acyl-CoA synthetase [Sorangium cellulosum 'So ce 56'] gi|161165917|emb|CAN97222.1| acyl-CoA synthetase [Sorangium cellulosum 'So ce 56'] Length=601 Score = 219 bits (559), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 169/530 (32%), Positives = 252/530 (48%), Gaps = 61/530 (11%) Query 49 LRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPI-PPREALKTTERFMTRLGPLL 107 L+ L L++G+ V + N +F+ FLG + G +PVPI PP K T L + Sbjct 54 LQALGLQKGDRVALILPDNADFIFAFLGAIRAGVIPVPIYPPTGLGKLTGYLENTLHIVA 113 Query 108 RHHRVLICTPAEHDE----IRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADW 163 + ++ T AE I+A A QI L R ++L Sbjct 114 KSGAKVLLTSAEIKRMLGTIQAQAPALEQIVAVEGL---------RGAREELKPVK---- 160 Query 164 PLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRA---MAVGSQFQHGDVMGSWLPLH 220 LDD ++Q+TSGST+ P+GVV+T+ NL +N+RA + +G + + D SWLPL+ Sbjct 161 --VELDDVCFLQFTSGSTSRPKGVVLTHGNLAANVRAIVDLGLGVR-ESVDTGVSWLPLY 217 Query 221 HDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAY 280 HDMGL+G + A L+ + F P FL P+ +L +T +F PNFA + Sbjct 218 HDMGLIGFVIAPLYYVNTITFLPPLLFLKRPVRWLETITRHRGNVSFGPNFAYALCVKRI 277 Query 281 HRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAV 340 R ++ G+DL R +EP+ A+ +R FA FA VG A YG+AE+T+AV Sbjct 278 --REQEMAGLDLSTWRVAGCGAEPIRADNLRAFAEKFAPVGFDEKAFVCSYGMAESTLAV 335 Query 341 SMSAPNTGFRT-------------------ETHAAAEVVTGGRVLPGYEVRI---DAAPG 378 S SA G +T ++ A+ +V G G+E+ + D A Sbjct 336 SFSALGAGLQTDAVDGETLWKEGKATPVPADSEGASSLVQCGSAFEGHEIAVFASDDAES 395 Query 379 AR------AGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDE 432 AR G ++LRG SV + G+ T DLG+L + ++ I GR E Sbjct 396 ARPLGDREVGELRLRGPSVMPGYFNDPDLTKEAFAGGWLRTGDLGYLAEGKVYICGRSKE 455 Query 433 VFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVLESPL-DSIIDKA 485 V IV+G N +P D+E+ S + V FG ERVV+V E+P D +A Sbjct 456 VIIVNGRNYYPQDLEWEASRVSGVRKGNVIAFGTMKPHNDRERVVIVFETPASDEQEKQA 515 Query 486 EADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTL 535 +R V A GL +D+++ V G +P T+SGKL+R + Y +G L Sbjct 516 LKGEVRRVVQQAMGLTVDDVVAVGSGILPKTSSGKLQRSKTRELYENGEL 565 >gi|209515271|ref|ZP_03264138.1| AMP-dependent synthetase and ligase [Burkholderia sp. H160] gi|209504252|gb|EEA04241.1| AMP-dependent synthetase and ligase [Burkholderia sp. H160] Length=556 Score = 218 bits (555), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 172/555 (31%), Positives = 256/555 (47%), Gaps = 72/555 (12%) Query 26 TCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPV 85 T D Y+ L A L L LK+GE + + F+ FLG G VPV Sbjct 25 TNGDEHYYPYEALEHEARKRARKLAALGLKKGERIALVILDPEAFILSFLGASFAGLVPV 84 Query 86 PIPPREAL--KTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAE 141 PI PR +L +T R+ + ++R R+L+ + + I + D + Sbjct 85 PIFPRGSLNFRTRARYAETVSHIVRSAGARMLLTSDTARETIEEVLAVDTGLECIV---- 140 Query 142 AGDEQFGRATAQQLAD--TATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMR 199 T + LAD D P DD ++QYTSGST+ P+GV++T+RNL++N R Sbjct 141 ---------TVESLADGEPPACDLPTVHPDDLCFLQYTSGSTSLPKGVMVTHRNLVANAR 191 Query 200 AM--AVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRL 257 A G + DV SWLPLHHDMGL+ S+ AL + +V + F+ P ++ Sbjct 192 AFLGPRGIDLRKQDVYVSWLPLHHDMGLI-SVLGALICDLPSVLISTEAFVRRPGLWMEA 250 Query 258 LTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATF 317 +T G T +F PNFA + + A R D+EG+DL +R +EP++A+ +R+F F Sbjct 251 ITKYGGTISFAPNFA--YALAARRTRDKDLEGLDLRPLRVAGCGAEPINAQALRQFCERF 308 Query 318 AGVGLAPTALGSGYGLAEATVAVS-----------------------MSAP-NTGFRTET 353 G AL YG+AEAT+A++ + AP +TG RT Sbjct 309 EPAGFRAEALLPCYGMAEATLAITFHDHGQPIVTDVVYASALGLGRAIPAPRDTGLRT-- 366 Query 354 HAAAEVVTGGRVLPGYEVRI-----DAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEE 408 E+V G G+E+RI P G I RG S+ Y + Sbjct 367 ---VELVGCGHPFAGHELRIVDESGRPLPERCVGEIVTRGPSITVGYYGQSDATADAYRD 423 Query 409 GFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV-- 466 G+ T DLG+L D++ I GR ++ ++HG N +P DIE+ + + V F V Sbjct 424 GWLQTGDLGYLAGDQLFICGRSKDLIVIHGSNHYPQDIEWAVAELPDVQSRGVIAFSVMR 483 Query 467 --NERVVVVLESPLDSIIDKAEADRLR----CQVVAATGLQLDELITVRRGAIPTTTSGK 520 +E +VV E AEA LR +V GLQ+ + V+ G++P T+SGK Sbjct 484 DGDETLVVCAEG------KPAEAAALRRAIAQKVAECAGLQVGHVAVVQAGSLPRTSSGK 537 Query 521 LKRRAVAQAYRDGTL 535 ++RR + G L Sbjct 538 VQRRRTKAQFEAGEL 552 >gi|335419445|ref|ZP_08550497.1| AMP-dependent synthetase and ligase [Salinisphaera shabanensis E1L3A] gi|334896610|gb|EGM34758.1| AMP-dependent synthetase and ligase [Salinisphaera shabanensis E1L3A] Length=651 Score = 216 bits (551), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 179/565 (32%), Positives = 266/565 (48%), Gaps = 65/565 (11%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 D ++Y+ L A + L+ ++ GEP+++ NL FL F G + G VPVPI Sbjct 29 DERGLNYRMLARSAEGRLAVLQEQGIQAGEPLILFVEDNLRFLQFFWGAIYGGIVPVPI- 87 Query 89 PREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFG 148 A T + +L + RH DE R AS I R E E Sbjct 88 ---AAGATPAQLEKLVRVWRHL----------DEPRIVASPK-HIERVRDFMEQRGE--- 130 Query 149 RATAQQLADTATADWPLC----------TLDDDAYVQYTSGSTAAPRGVVITYRNLLSNM 198 R T ++LA+ + +D P T D A++Q++SGST P+GVV+T+ N+L+N+ Sbjct 131 RDTGERLAERSLSDEPPAVETPAERASLTPQDTAFIQFSSGSTGDPKGVVLTHANVLANI 190 Query 199 RAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLL 258 A++ GSQF +V SW+PL HDMGL+G ++N TP F PL +L Sbjct 191 EAISSGSQFGRDEVALSWMPLTHDMGLIGFHLTLVYNGFVHYLMTPDLFARRPLLWLEKA 250 Query 259 TSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFA 318 AT PNF + A +G +DL +R + +EP+ +R F AT A Sbjct 251 AEIRATLLCSPNFGYRHTLRAIAAKGR--PELDLSSVRLIYNGAEPIAPALVREFLATLA 308 Query 319 GVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVVTGG--RVLPG-------- 368 GL T + + YGLAEA++A + AP G R+ + A E+ G R PG Sbjct 309 PTGLKATTMFAVYGLAEASLAATFPAPGRGLRSVSVARGELGLGDTVRYDPGAQALELVC 368 Query 369 -------YEVRI-----DAAPGARAGTIKLRGDSVAAKAYVG-GKKLDALDEEGFCDTHD 415 E+++ DA G + +RG +V A Y DAL +G+ DT D Sbjct 369 LGTPVRSTELKLADAQGDAVEEGVVGRVWIRGANVTAGYYGNPNANADALVGDGWLDTGD 428 Query 416 LGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVN-----ERV 470 LGF D E+VI GR E+ V+G+N +P DIE +++ K+A GV E+ Sbjct 429 LGFCYDGELVITGRAKEIIFVNGQNHYPQDIEALLQDVPGAELNKLAAAGVQAPSTTEQA 488 Query 471 VVVLESPLDSIIDKAEADR-LRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQA 529 +V+ + D A R LR + GL +++ + R +P TTSGKL+R +A+ Sbjct 489 LVLFVVFRGHLEDFAAIARELRGALNQRAGLVASQVLPISR--MPKTTSGKLQRSLLARQ 546 Query 530 YRDG----TLPRLATHAWTADPDSA 550 Y +G + L A+P+SA Sbjct 547 YAEGEFAAIVAELDKLLGAAEPESA 571 >gi|115378536|ref|ZP_01465692.1| saframycin Mx1 synthetase B [Stigmatella aurantiaca DW4/3-1] gi|310822384|ref|YP_003954742.1| saframycin mx1 synthetase b [Stigmatella aurantiaca DW4/3-1] gi|115364458|gb|EAU63537.1| saframycin Mx1 synthetase B [Stigmatella aurantiaca DW4/3-1] gi|309395456|gb|ADO72915.1| Saframycin Mx1 synthetase B [Stigmatella aurantiaca DW4/3-1] Length=583 Score = 214 bits (546), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 163/523 (32%), Positives = 261/523 (50%), Gaps = 41/523 (7%) Query 33 ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREA 92 ++Y+ + R AAC R ++ G+ +L T+ + F GLM GAVP + P Sbjct 31 LAYRAMPERIAACAEHFRAQGIQPGDRILFPFETSEAVILSFFGLMALGAVPFSVKP-YI 89 Query 93 LKTTE----RFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFG 148 L T + F++RL +R+L ++ + S + + R L AG Sbjct 90 LSTPKGAYRDFLSRLSSRHGVNRIL--------DVPSVRSLELALVR-VPLPPAG----- 135 Query 149 RATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQ 208 A A A + D A+VQ++SGSTA P+GV IT+RNL +N+R + Sbjct 136 -------ARLAGARPRVPEEDALAFVQFSSGSTAFPKGVPITWRNLHANLRMIQNQGALC 188 Query 209 HGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFM 268 D SWLPL+HDMGLVG + A ++ ++ T P FL DP+G+L L+ T + Sbjct 189 AQDRCVSWLPLYHDMGLVGGMLACMYGHCDSLLTQPMSFLMDPMGWLEFLSEHRGTLAVI 248 Query 269 PNFALEWLINAYHRRGA-DIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTAL 327 PNFA+++ + + GA ++ +DL +R + + SEP++ + RF A GL A+ Sbjct 249 PNFAIDYTLKILNGLGAEELRELDLSALRTVYLGSEPINIANLERFTVLLAPQGLRREAI 308 Query 328 GSGYGLAEATVAVSMSAPNTGFRTETHAAAE-VVTGGRVLPGYEVRIDAAPG-----ARA 381 YG+AE + VS G+R T + ++ G L +EVR+ G Sbjct 309 KPCYGMAEVVLMVSCVG-EEGWRVVTGPHGQPAISVGYPLSEFEVRLRTEEGRVSGEREL 367 Query 382 GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENR 441 G I+LR S+A Y + L EEGF T DLGF+ D E+ I GR ++ ++G++ Sbjct 368 GQIELRSGSLAQAYYADERPLRG--EEGFYPTGDLGFMQDGELFITGRLNDRIKINGQSY 425 Query 442 FPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDSII-DKAEADR-LRCQVVAATG 499 F D E + + + A RVVV+ E ++ D++ R + ++ A G Sbjct 426 FSSDFEQAVERLAFIRSGRSAVIQAQGRVVVLAEVNGPEVLEDRSVGQRQVAAAILEAMG 485 Query 500 LQ--LDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLAT 540 + L++++ +R G +P T+SGKL+RRA+ +AY G + R+AT Sbjct 486 VTVALEDVLFIRYGQLPKTSSGKLQRRAITEAYEQGHI-RVAT 527 >gi|215919292|ref|NP_820905.2| acyl-CoA synthetase [Coxiella burnetii RSA 493] gi|206584177|gb|AAO91419.2| acyl-CoA synthetase [Coxiella burnetii RSA 493] Length=936 Score = 214 bits (544), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 162/543 (30%), Positives = 244/543 (45%), Gaps = 50/543 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L RA L LK E V I T+ +F FLG ++ G +PVPI Sbjct 138 EETIIRYGELYTRAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 197 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 198 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 247 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 248 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 303 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 304 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 363 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + +D+EG+DL R + SE +H + +R F F G Sbjct 364 ISPGPNFAYDLCVKKIE--DSDLEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 421 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE + ++ N G T E V+ G V Sbjct 422 EAIFPAYGLAECALGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 481 Query 366 LPGYEVRI----DAAPGARA-GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI D R G I+ +G S Y + A+ G+ T DLG+L Sbjct 482 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYRNSEATMAIYHNGWWATGDLGYLA 541 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + ++ VA FGV E++++V Sbjct 542 EGELFITGRKKDLIIKAGRNYHPTEIEAMASLAEGVRKSCVAAFGVADEKRGTEKLIIVA 601 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 602 ETKEDKKIQPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 661 Query 535 LPR 537 L R Sbjct 662 LSR 664 >gi|161830319|ref|YP_001597743.1| acyltransferase family protein [Coxiella burnetii RSA 331] gi|161762186|gb|ABX77828.1| acyltransferase family protein [Coxiella burnetii RSA 331] Length=852 Score = 213 bits (543), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 162/549 (30%), Positives = 246/549 (45%), Gaps = 50/549 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L RA L LK E V I T+ +F FLG ++ G +PVPI Sbjct 55 EETIIRYGELYTRAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 114 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 115 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 164 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 165 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 220 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 221 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 280 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + +D+EG+DL R + SE +H + +R F F G Sbjct 281 ISPGPNFAYDLCVKKIE--DSDLEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 338 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE + ++ N G T E V+ G V Sbjct 339 EAIFPAYGLAECALGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 398 Query 366 LPGYEVRIDAAPGARA-----GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI R G I+ +G S Y + A+ G+ T DLG+L Sbjct 399 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYRNSEATMAIYHNGWWATGDLGYLA 458 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + ++ VA FGV E++++V Sbjct 459 EGELFITGRKKDLIIKAGRNYHPTEIEAMASLAEGVRKSCVAAFGVADEKRGTEKLIIVA 518 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 519 ETKEDKKIHPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 578 Query 535 LPRLATHAW 543 L R + A+ Sbjct 579 LSRPSRSAF 587 >gi|296160928|ref|ZP_06843740.1| AMP-dependent synthetase and ligase [Burkholderia sp. Ch1-1] gi|295888817|gb|EFG68623.1| AMP-dependent synthetase and ligase [Burkholderia sp. Ch1-1] Length=941 Score = 212 bits (539), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 171/559 (31%), Positives = 250/559 (45%), Gaps = 50/559 (8%) Query 20 DRTLTITCEDSEV---ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLG 76 RT I ED +SY +L RAAA LR + G+ V + T ++ F+ Sbjct 120 QRTHIIFLEDGATPAGLSYGELYRRAAAAASGLRSRGIGPGDTVALMLATGWDYFVSFIA 179 Query 77 LMLHGAVPVPIPPREALKTTERFMTRLGPLLRH--HRVLICTPAEHDEIRAAASTDCQIS 134 +++ GA PVPI P + E + R +L + + LI +P E+ + Sbjct 180 ILMSGATPVPIYPPARVSQIEEHVRRHAAVLSNAGAKALIASP----EV-------AGVG 228 Query 135 RFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNL 194 R L + TA Q+ D A +QYTSGST P+GV++T+ NL Sbjct 229 RLLKLYVPALQHV--LTAAQIGVDRNETPVPGAAADMALLQYTSGSTGDPKGVMLTHANL 286 Query 195 LSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGF 254 L+N+RAM Q GDV+ SWLPL+HDMGL+G+ F L+ + V P FL P + Sbjct 287 LANIRAMGSRMQITAGDVLVSWLPLYHDMGLIGAWFGPLYFGMPLVIMPPTVFLARPELW 346 Query 255 LRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFA 314 L+ + T T PNFA H A + G+DL +R +EPV A +R F+ Sbjct 347 LQSIQRYRGTLTAAPNFAYAHCTQ--HLDEASLAGLDLSSLRFAFCGAEPVSAATLRSFS 404 Query 315 ATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTE------------------THAA 356 A F+ G A+ YGLAE T+ +S P G + + A Sbjct 405 ARFSQYGFDARAVTPVYGLAENTLGLSFPPPGRGLHVDRVERVALGATGQALPAPSSEDA 464 Query 357 AEVVTGGRVLPGYEVRI-----DAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFC 411 EVV G L +VRI P R G I+ RG S +A + + + L G+ Sbjct 465 VEVVGCGEALDSVDVRIVDDNAQEQPERRVGHIEFRGPSASAGYFHNPAQTERLIHNGWL 524 Query 412 DTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV----- 466 DT DLG+L D E+ I GR ++ I G + FPY++E I E VA G Sbjct 525 DTGDLGYLADRELFITGRAKDLIIRGGRHIFPYELEEAIGRLPEVPPGGVAVCGSIDRAS 584 Query 467 -NERVVVVLESPLDSIIDKAE-ADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRR 524 ER+V+++E+ L + + R+ + V G +++ V I T SGK++ Sbjct 585 GTERIVILVETALTQAAAREQLLARIHARTVELLGAPAEQVCLVAPETILKTPSGKIRHA 644 Query 525 AVAQAYRDGTLPRLATHAW 543 A + + G A AW Sbjct 645 ATLEQFERGGRASPARPAW 663 >gi|238024664|ref|YP_002908896.1| Saframycin Mx1 synthetase [Burkholderia glumae BGR1] gi|237879329|gb|ACR31661.1| Saframycin Mx1 synthetase [Burkholderia glumae BGR1] Length=1819 Score = 211 bits (537), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 188/576 (33%), Positives = 263/576 (46%), Gaps = 86/576 (14%) Query 21 RTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLH 80 R LT ++ +S+ +L RA A L R + RGEPVL+ L+F++ F G + Sbjct 77 RFLTDGVVEAPRLSFAELDRRATAIAARLAR-ECPRGEPVLLLYRPGLDFIAAFFGCLYA 135 Query 81 GAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDC---QISRFT 137 G VP P T R +R+ AA DC I Sbjct 136 GCAAVPAYPPSGRAT------------RRNRL------------AAIIADCGAGAILTSD 171 Query 138 ALAEAGDEQFGRATAQQLA-------------DTATADWPLCTLDDDAYVQYTSGSTAAP 184 L EA E+ +A A + + AD A++QYTSGST P Sbjct 172 ELVEAIREEIAQADVPSRAGVIGTDALLAAPGEASDADGAALPASHLAFLQYTSGSTGRP 231 Query 185 RGVVITYRNLLSNMRAMAVGSQFQHGD--VMGSWLPLHHDMGLVGSLFAALFNSVSAVFT 242 +GV +T+RNLL+N RA+ G F HG V W PL+HDMGL+G++ ++ + +V Sbjct 232 KGVRVTHRNLLANERAIREG--FGHGPDTVFVGWCPLYHDMGLIGNVLQPVYLGIPSVLM 289 Query 243 TPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIAS 302 +P FL PL +LR +++ GAT + PNFA E + A AD G+DL R + Sbjct 290 SPFEFLQQPLKWLRAISTYGATTSGGPNFAYE--LCATRIAEADKAGLDLSSWRVAFNGA 347 Query 303 EPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRT----------- 351 EP+ A + +FAA FA G A+ YG+AE T+ VS + P G T Sbjct 348 EPIRASTLDKFAAAFADYGFDAGAMFPCYGMAETTLFVSGAVPGAGALTRRVDALALQAG 407 Query 352 ------ETHAAAEVVTGGRVLPGYEVRIDAAPGARA------GTIKLRGDSVAAKAYVG- 398 + AAE+V+ GRV +VRI RA G I +RG SVA + Sbjct 408 RCVDAADGQPAAELVSSGRVGGDQQVRIVDPHSLRARGPGEIGEIWVRGGSVADGYWNRE 467 Query 399 -------GKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIR 451 ++ D F T DLG L E+ + GR E+ I+ G N +P DIE + Sbjct 468 DDTRAQFDARIAGEDSPPFLRTGDLGLLDGGELYVTGRLKELIIIRGRNHYPTDIEQTVE 527 Query 452 GESEQHRTKV-ACFGVN----ERVVVVLE---SPLDSIIDKAEADRLRCQVVAATGLQLD 503 S R A F ++ ER+VVV E + S+ + R V AA G+ L Sbjct 528 QSSADFRAGCGAAFAIDGEDGERLVVVQEIQRAVRKSLDAEEAGRRAAAAVAAAHGIPLH 587 Query 504 ELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLA 539 EL+ V+ G +P T+SGK +R V Q Y +G LP LA Sbjct 588 ELVLVQAGVVPKTSSGKNQRTLVRQHYLNGELPVLA 623 >gi|186471740|ref|YP_001863058.1| AMP-dependent synthetase and ligase [Burkholderia phymatum STM815] gi|184198049|gb|ACC76012.1| AMP-dependent synthetase and ligase [Burkholderia phymatum STM815] Length=962 Score = 211 bits (536), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 174/540 (33%), Positives = 256/540 (48%), Gaps = 70/540 (12%) Query 49 LRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLR 108 LR++ + G+ V + T ++ +CF G++L GA+ VP+ P + + R +L Sbjct 180 LRQIGVNPGDTVALMLPTGSDYFACFAGILLLGAIVVPVYPPAQSARIDDHLARHAAILS 239 Query 109 HHRVLICTPAEHDEIRAAASTDCQISRFTALAE--AGDEQFGRATAQQLADTATADWPLC 166 R + H + + +R L E A + G A+Q A Sbjct 240 DARARVMIVPSHAFVAGVMAK----ARIPTLHEIVAVPQLMGEMDAEQYVPRA------- 288 Query 167 TLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLV 226 +D A +QYTSGST P+GVV+T+ NLL+N+RAM + + DV SWLPL+HDMGL+ Sbjct 289 --EDVALLQYTSGSTGTPKGVVLTHANLLANIRAMGHTALIEEHDVFVSWLPLYHDMGLI 346 Query 227 GSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGAD 286 G+ F L+ + V +P FL P +L ++ AT T PNFA E A D Sbjct 347 GAWFGPLYFGIPLVLMSPLTFLARPARWLHAISDYHATITAAPNFAYERC--ARRVDDTD 404 Query 287 IEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPN 346 +E +DL +R +EPV A MR FA+ FA G TAL YGLAE T+ ++ S P Sbjct 405 LEDVDLSSLRLAFCGAEPVSAATMRAFASRFARNGFRHTALTPVYGLAENTLGLAFSEPG 464 Query 347 TGFRT---------ETHAAA---------EVVTGGRVLPGYEVRIDAAPGAR-----AGT 383 G RT ++ AA E+V+ GR LP ++RI A G G Sbjct 465 RGVRTDCISRVRLADSQRAAPAESPDEVLELVSCGRALPRNQIRIMDADGNEVSERAVGR 524 Query 384 IKLRGDSVAAKAYVGGKKLDA-LDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRF 442 I+ R S A + Y L A L +G+ DT DLG++ D+E+ I GR ++ I G + + Sbjct 525 IEFRSPS-ATRGYFQNPNLTARLIHDGWLDTGDLGYMADEELFITGRVKDLVIRAGRHFY 583 Query 443 PYDIEFIIRGESEQHRTK-VACFGV------NERVVVVLES---------PLDSIIDKAE 486 PY++E + G RT VA G +R++V+ E+ + S I++A Sbjct 584 PYELEAAV-GRLPGVRTGCVAVCGTPDVETGTDRLLVIAETRATAPATLAAIRSGINEAS 642 Query 487 ADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAY---RDGTLPRLATHAW 543 VA G +E+ V +I T+SGK++ A Y R LPR A W Sbjct 643 --------VALLGAPPEEVALVPPHSILKTSSGKIRHAATLDLYMRSRGNLLPRPAWRQW 694 >gi|300311697|ref|YP_003775789.1| acyltransferase family protein [Herbaspirillum seropedicae SmR1] gi|300074482|gb|ADJ63881.1| acyltransferase family protein [Herbaspirillum seropedicae SmR1] Length=932 Score = 210 bits (534), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 163/555 (30%), Positives = 253/555 (46%), Gaps = 69/555 (12%) Query 33 ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREA 92 I Y DL+ A L + L + V + T+ ++L+CF G++ G +PVPI P Sbjct 144 IRYCDLLDDAKMVATALLQGGLLPKQTVALMLPTSRDYLACFFGILFAGGIPVPIYPPAR 203 Query 93 LKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATA 152 L + L RHH +L ++ + LAEA + F R Sbjct 204 LSRID------DQLRRHHHIL---------------SNSEAVFIVTLAEA--KPFARMLQ 240 Query 153 QQLADTATADWPL------------CTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRA 200 +L + P + DD A++QYTSGST P+GV +T+ NLLSN+RA Sbjct 241 AKLPGLMSILTPAELKSSAGFLRYRPSRDDIAFIQYTSGSTGDPKGVTLTHANLLSNVRA 300 Query 201 MAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTS 260 + S+ D+ SWLPL+HDMGL+G+ F +L++ + V +P FL P +L L+ Sbjct 301 LGKVSRVSPSDIFVSWLPLYHDMGLIGAWFGSLYHGIPLVLMSPMTFLAQPSIWLDQLSR 360 Query 261 SGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGV 320 T + PNFA E + H A + +DL R + SEPV A + FA F G Sbjct 361 HRGTISAAPNFAYELCLR--HVNDALLSSLDLSCWRLALNGSEPVSATTLASFAKRFEGC 418 Query 321 GLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHA--------------------AAEVV 360 GL A+ YGLAE +V +S + R ++ + +V Sbjct 419 GLRYRAMTPVYGLAECSVGLSFPVLDADPRIDSISRQLLAREGKALHPDSADAADTIKVP 478 Query 361 TGGRVLPGYEVRI--DAA---PGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHD 415 + G LPG+++R+ DA P G ++ RG S Y K L +G+ D+ D Sbjct 479 SCGPALPGHQIRVVDDAGFELPSRCVGRLEFRGPSATHGYYRNPKATANLFHDGWLDSGD 538 Query 416 LGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVN------ER 469 +L + E+ I+GR ++ G N +PYD+E + R VA FG N ER Sbjct 539 YAYLAEGEVYIVGRIKDLIKRGGRNLYPYDLEQAVSHVRGIRRGGVAVFGSNDPENGAER 598 Query 470 VVVVLESPLDSIIDKAEADR-LRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQ 528 +V+V E+ + +A R + + G D+++ V + T+SGK++R A Sbjct 599 LVIVAETEIQDTKLQASMRRAVHEASIDVIGEPPDDVVFVPPHWVLRTSSGKIRRLACKA 658 Query 529 AYRDGTLPRLATHAW 543 AY +G + + +W Sbjct 659 AYEEGRVSHRFSMSW 673 >gi|162450802|ref|YP_001613169.1| acyl-CoA synthetase [Sorangium cellulosum 'So ce 56'] gi|161161384|emb|CAN92689.1| acyl-CoA synthetase [Sorangium cellulosum 'So ce 56'] Length=607 Score = 209 bits (532), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 181/557 (33%), Positives = 273/557 (50%), Gaps = 40/557 (7%) Query 13 QQISACTDRTLTITCEDSE--VISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEF 70 QQ S DR +T E ISY +L A LR+L L++G+ V + EF Sbjct 9 QQNSVHADRAVTFVRSSGEERAISYAELWLEARRRAYALRKLGLRKGDRVALILTEADEF 68 Query 71 LSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAAS 128 + F+G + G V VP+ P ++L E + + +L VL+ + I A + Sbjct 69 VLTFVGALTAGIVAVPMYPPQSLAKLEAYGETVQHILEASGASVLVTNEQLKEMIDAYLA 128 Query 129 TDCQISR--FTALAEAGDEQFGRATAQQLADTATADWPL-CTLDDDAYVQYTSGSTAAPR 185 + + SR L + +D + A P +LDD A++Q+TSGST+ P+ Sbjct 129 ANAE-SREALPGLRVVLERDLRARDGSDASDASHAAEPWRVSLDDLAFLQFTSGSTSRPK 187 Query 186 GVVITYRNLLSNMRA-MAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTP 244 GV++T+RNL N A M G + D SWLPL+HDMGL+G + A L+ V +F Sbjct 188 GVMVTHRNLTVNSHAIMFDGLRSTPEDRGVSWLPLYHDMGLIGFVIAPLYALVPVMFLPT 247 Query 245 HRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEP 304 F+ P +L + T TF PNFA A A DL +R L +EP Sbjct 248 TAFIRRPSLWLDAIHRFRGTITFAPNFAFALATRAVT--DAQAGSWDLSCVRALGCGAEP 305 Query 305 VHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMS---APNTGFRTETH------- 354 + A+ +R F F+ GL P ++ YG+AEAT+A++ S AP T R + Sbjct 306 IQADVLRAFLRRFSERGLRPESILPSYGMAEATLAITFSDLKAPLTTDRVDAKAMQAGKA 365 Query 355 ------AAAEVVTGGRVLPGYEVRI---DAAP-GAR-AGTIKLRGDSVAAKAYVGGKKLD 403 A+ E+V+ GR LP +E+ I D +P G R G I +RG SVAA + + + Sbjct 366 WPANGGASLELVSCGRPLPCHELIIAGPDGSPLGPREVGEIWVRGPSVAAGYFNEPEATE 425 Query 404 ALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFI---IRGESEQHRTK 460 A G+ T DLG+ V E+ + GR ++ I+ G+N FP DIE I + G + H Sbjct 426 AAFGGGWLRTGDLGYTVAGEVYLCGRSKDLIILGGKNYFPQDIERIASSVEGVRDGHCVA 485 Query 461 VACFGVN--ERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTS 518 +C ER +VV E+ S+ A+A + V A G+QL E+ ++RG + T+S Sbjct 486 FSCLTAEGAERAIVVAEAK-RSVAGVAQA--ITQAVRAQLGVQLSEVALIKRGTLAKTSS 542 Query 519 GKLKRRAVAQAYRDGTL 535 GK++RR + + + G L Sbjct 543 GKVRRREMKRRFEAGEL 559 >gi|91789248|ref|YP_550200.1| AMP-dependent synthetase and ligase [Polaromonas sp. JS666] gi|91698473|gb|ABE45302.1| AMP-dependent synthetase and ligase [Polaromonas sp. JS666] Length=942 Score = 209 bits (532), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 183/594 (31%), Positives = 268/594 (46%), Gaps = 72/594 (12%) Query 3 AALLSPAIAWQQISACTDRTLTITCEDSEV---ISYQDLIARAAACIPPLRRLDLKRGEP 59 AA L + W + + I DS +SY DL AA L + G+P Sbjct 116 AATLQEVLDWHVRAHPQREHIAIDNGDSAAPTRLSYADLQQGAAGVAAGLLDRGFQPGQP 175 Query 60 VLITAHTNLEFLSCFLGLMLHGAVPVPI-PPREALKTTERFMTRLGPLLRHHRVLICTPA 118 V + T E+ F G++L G +PVPI PP A + E +G L Sbjct 176 VALMLPTGPEYFFSFAGILLAGGIPVPIYPPARAAQIEEHLQRHVGIL------------ 223 Query 119 EHDEIRAAASTDCQISRFTALAEAGDEQFGR----ATAQQL-ADTATADWPLCTLDDDAY 173 A A+ + R LA Q T ++L A TA+ + +D A Sbjct 224 ----TNALATALITVPRARVLATLLKSQVPSLRMVCTVEELSASTASPERVTAHANDIAL 279 Query 174 VQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAAL 233 +QYTSGST++P+GVV+T+ NLL+N+RAM Q DV SWLPL+HDMGL+G+ +L Sbjct 280 LQYTSGSTSSPKGVVLTHANLLANLRAMGQALQVSSEDVFVSWLPLYHDMGLIGAWLGSL 339 Query 234 FNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLH 293 + + V +P FL P +L + T + PNF E + A +EG+DL Sbjct 340 YYAYPLVVMSPLTFLARPERWLWAVHRHRGTLSGGPNFGYELCLRKLDE--AALEGLDLS 397 Query 294 KMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGF---R 350 R +EPV A M+ F FA GL P AL YGLAEAT+ ++ G R Sbjct 398 SWRFAFNGAEPVSATTMQEFQQRFACYGLRPQALAPVYGLAEATLGLTFPPQGRGLLVDR 457 Query 351 TETHAAAE----------------VVTGGRVLPGYEVRIDAAPGA-----RAGTIKLRGD 389 +T A + VV GR LPG+EVR+ A G + G + +G Sbjct 458 IDTQAFSHSGRALPAASSTSGVRLVVACGRPLPGHEVRLVDATGCEVAERQEGRLLFKGP 517 Query 390 SVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFI 449 S + + K+ L + + D+ D ++ ++ I GR +V I G +PYD+E Sbjct 518 SATSGYFRNPKETRRLFDGEWLDSGDYAYMAQGDVYITGRAKDVIIRGGRQIYPYDLEEA 577 Query 450 IRGESEQHRTKVACFGV------NERVVVVLESPLDSIIDKAEADRLRCQV----VAATG 499 + + VA FG +ERVVV+ E+ + +A A +LR Q+ V G Sbjct 578 VGAIPSVRKGCVAVFGSPDPMTRSERVVVMAET--RGLPPEALA-QLRRQINSAAVGVLG 634 Query 500 LQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDG----TLP----RLATHAWTA 545 D+++ V + T+SGK++R A + Y G T P ++A AW A Sbjct 635 APPDDVVLVPPHTVLKTSSGKIRRAASRELYETGGASATQPAPWQQIARFAWQA 688 >gi|209363707|ref|YP_001423619.2| acyl-CoA synthetase [Coxiella burnetii Dugway 5J108-111] gi|207081640|gb|ABS78186.2| acyl-CoA synthetase [Coxiella burnetii Dugway 5J108-111] Length=936 Score = 209 bits (532), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 162/549 (30%), Positives = 245/549 (45%), Gaps = 50/549 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L RA L LK E V I T+ +F FLG ++ G +PVPI Sbjct 138 EETIIRYGELYTRAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 197 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 198 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 247 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 248 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 303 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 304 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 363 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + + +EG+DL R + SE +H + +R F F G Sbjct 364 ISPGPNFAYDLCVKKIE--DSALEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 421 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE + ++ N G T E V+ G V Sbjct 422 EAIFPAYGLAECALGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 481 Query 366 LPGYEVRI----DAAPGARA-GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI D R G I+ +G S Y + A+ G+ T DLG+L Sbjct 482 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYRNSEATMAIYHNGWWATGDLGYLA 541 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + + VA FGV E++++V Sbjct 542 EGELFITGRKKDLIIKAGRNYHPTEIEAMASLAEGVRKGCVAAFGVADEKRGTEKLIIVA 601 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 602 ETKEDKKIHPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 661 Query 535 LPRLATHAW 543 L R + A+ Sbjct 662 LSRPSRSAF 670 >gi|212211705|ref|YP_002302641.1| acyl-CoA synthetase [Coxiella burnetii CbuG_Q212] gi|212010115|gb|ACJ17496.1| acyl-CoA synthetase [Coxiella burnetii CbuG_Q212] Length=936 Score = 209 bits (531), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 162/549 (30%), Positives = 245/549 (45%), Gaps = 50/549 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L A L LK E V I T+ +F FLG ++ G +PVPI Sbjct 138 EETIIRYGELYTGAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 197 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 198 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 247 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 248 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 303 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 304 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 363 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + +D+EG+DL R + SE +H + +R F F G Sbjct 364 ISPGPNFAYDLCVKKIE--DSDLEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 421 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE + ++ N G T E V+ G V Sbjct 422 EAIFPAYGLAECALGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 481 Query 366 LPGYEVRI----DAAPGARA-GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI D R G I+ +G S Y + A+ G+ T DLG+L Sbjct 482 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYRNSEATMAIYHNGWWATGDLGYLA 541 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + + VA FGV E++++V Sbjct 542 EGELFITGRKKDLIIRAGRNYHPTEIEAMASLAEGVRKGCVAAFGVADEKRGTEKLIIVA 601 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 602 ETKEDKKIHPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 661 Query 535 LPRLATHAW 543 L R + A+ Sbjct 662 LSRPSRSAF 670 >gi|212217721|ref|YP_002304508.1| acyl-CoA synthetase [Coxiella burnetii CbuK_Q154] gi|212011983|gb|ACJ19363.1| acyl-CoA synthetase [Coxiella burnetii CbuK_Q154] Length=936 Score = 209 bits (531), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 162/549 (30%), Positives = 244/549 (45%), Gaps = 50/549 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L RA L LK E V I T+ +F FLG ++ G +PVPI Sbjct 138 EETIIRYGELYTRAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 197 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 198 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 247 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 248 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 303 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 304 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 363 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + + +EG+DL R + SE +H + +R F F G Sbjct 364 ISPGPNFAYDLCVKKIE--DSALEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 421 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE ++ N G T E V+ G V Sbjct 422 EAIFPAYGLAECAFGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 481 Query 366 LPGYEVRI----DAAPGARA-GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI D R G I+ +G S Y + A+ G+ T DLG+L Sbjct 482 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYGNSEATMAIYHNGWWATGDLGYLA 541 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + + VA FGV E++++V Sbjct 542 EGELFITGRKKDLIIKAGRNYHPTEIEAMASLAEGVRKGYVAAFGVADEKRGTEKLIIVA 601 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 602 ETKEDKKIHPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 661 Query 535 LPRLATHAW 543 L R + A+ Sbjct 662 LSRPSRSAF 670 >gi|165918760|ref|ZP_02218846.1| acyltransferase family protein [Coxiella burnetii RSA 334] gi|165917588|gb|EDR36192.1| acyltransferase family protein [Coxiella burnetii RSA 334] Length=853 Score = 209 bits (531), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 161/549 (30%), Positives = 244/549 (45%), Gaps = 50/549 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L RA L LK E V I T+ +F FLG ++ G +PVPI Sbjct 55 EETIIRYGELYTRAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 114 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 115 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 164 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 165 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 220 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 221 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 280 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + + +EG+DL R + SE +H + +R F F G Sbjct 281 ISPGPNFAYDLCVKKIE--DSALEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 338 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE + ++ N G T E V+ G V Sbjct 339 EAIFPAYGLAECALGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 398 Query 366 LPGYEVRIDAAPGARA-----GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI R G I+ +G S Y + A+ G+ T DLG+L Sbjct 399 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYGNSEATMAIYHNGWWATGDLGYLA 458 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + + VA FGV E++++V Sbjct 459 EGELFITGRKKDLIIKAGRNYHPTEIEAMASLAEGVRKGCVAAFGVADEKRGTEKLIIVA 518 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 519 ETKEDKKIHPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 578 Query 535 LPRLATHAW 543 L R + A+ Sbjct 579 LSRPSRSAF 587 >gi|153206239|ref|ZP_01945502.1| acyltransferase family protein [Coxiella burnetii 'MSU Goat Q177'] gi|120577369|gb|EAX33993.1| acyltransferase family protein [Coxiella burnetii 'MSU Goat Q177'] Length=853 Score = 209 bits (531), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 162/549 (30%), Positives = 244/549 (45%), Gaps = 50/549 (9%) Query 29 DSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP 88 + +I Y +L RA L LK E V I T+ +F FLG ++ G +PVPI Sbjct 55 EETIIRYGELYTRAKEFAQGLVGKGLKPSETVAIMLPTSADFFYSFLGTLMAGGIPVPIY 114 Query 89 PREALKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQ 146 P E + R +L + R LI RAAA + S +L E Sbjct 115 PPFRADQIEEYAKREAFILHNAGVRFLITFK------RAAALSKLLQSFVPSLLEV---- 164 Query 147 FGRATAQQLADTATADWPLCTLD--DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 T + L D +AD P ++ D +QYTSGST P+GV++ + NLL+N+ A Sbjct 165 ---TTVKALTDI-SADLPTLDIEATDPVLIQYTSGSTGNPKGVLLNHANLLANISAYGKT 220 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 Q D SWLPL+HDMGL+G+ + ++ + +P FL P +L + T Sbjct 221 LNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGLPLTLLSPFTFLSRPEKWLWAIHYHRGT 280 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + PNFA + + + +EG+DL R + SE +H + +R F F G Sbjct 281 ISPGPNFAYDLCVKKIE--DSALEGLDLSSWRVALNGSEMIHPDTLRNFEKRFRKYGFKK 338 Query 325 TALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAEVVTGGRV 365 A+ YGLAE ++ N G T E V+ G V Sbjct 339 EAIFPAYGLAECAFGLTFPPLNRGPNIDRIERLPYEKNNTAVPLTTRDKKYYEFVSCGSV 398 Query 366 LPGYEVRI----DAAPGARA-GTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLV 420 L G+E+RI D R G I+ +G S Y + A+ G+ T DLG+L Sbjct 399 LEGHEIRIVDDNDNRVAERTIGNIQFKGPSAMQGYYGNSEATMAIYHNGWWATGDLGYLA 458 Query 421 DDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVL 474 + E+ I GR+ ++ I G N P +IE + + VA FGV E++++V Sbjct 459 EGELFITGRKKDLIIKAGRNYHPTEIEAMASLAEGVRKGYVAAFGVADEKRGTEKLIIVA 518 Query 475 ESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGT 534 E+ D I + +V++ G+ DE++ V +P T+SGKL+R + Q Y G Sbjct 519 ETKEDKKIHPEIKKEIVDKVISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGK 578 Query 535 LPRLATHAW 543 L R + A+ Sbjct 579 LSRPSRSAF 587 >gi|288941226|ref|YP_003443466.1| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Allochromatium vinosum DSM 180] gi|288896598|gb|ADC62434.1| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Allochromatium vinosum DSM 180] Length=947 Score = 209 bits (531), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 166/517 (33%), Positives = 237/517 (46%), Gaps = 49/517 (9%) Query 54 LKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVL 113 LK G V I T L++ F G+++ G VPVPI P + E L RH R+L Sbjct 183 LKSGGTVAIMLPTGLDYFFAFFGVLIAGGVPVPIYPPARPQQLEDH------LRRHARLL 236 Query 114 ----ICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLD 169 +C E R A +A + E T + A + ADW Sbjct 237 DNAGVCVLITVSEARHVARL------LSAQVPSLHEILTLETPDETAPLSRADWAAPNAG 290 Query 170 DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSL 229 D A++QYTSGST P+GV++T+ +LL+N+RAM DV SWLPL+HDMGL+G+ Sbjct 291 DLAFLQYTSGSTGDPKGVMLTHADLLANIRAMGEAIAIAPDDVFVSWLPLYHDMGLIGAW 350 Query 230 FAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEG 289 +L+ V + +P FL P +L+ +++ T + PNFA E + + +EG Sbjct 351 LGSLYFGVPLIVMSPLAFLARPRRWLQAISAHRGTLSAAPNFAYELCLTRLS--DSQLEG 408 Query 290 IDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGF 349 +DL RR +EPV AE + RFA FA GL P AL YGLAEA V ++ G Sbjct 409 LDLRSWRRAFNGAEPVSAETLHRFAERFAPCGLRPEALAPVYGLAEAAVGLAFPPVERGP 468 Query 350 RTET-------------------HAAAEVVTGGRVLPGYEVRI-----DAAPGARAGTIK 385 R + A VV GR LPGY VR+ P G ++ Sbjct 469 RIDCIDRARFAGSGYALPVACDDPDAMAVVACGRPLPGYRVRVVDESGRERPERHEGLLQ 528 Query 386 LRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYD 445 +G S Y + L +G+ +T D +L +I + GR ++ I G N +PY+ Sbjct 529 FQGPSATQGYYRHPEATARLIRDGWHETGDRAYLAGGDIHLTGRVKDLIIRGGRNLYPYE 588 Query 446 IEFIIRGESEQHRTKVACFGV------NERVVVVLESP-LDSIIDKAEADRLRCQVVAAT 498 +E + + R V F +ER+V+V ES D A A R R + Sbjct 589 VEQALGELTGIRRGCVVAFAARDARQGSERLVIVAESKERDPERRAALAQRARERATEVL 648 Query 499 GLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTL 535 GL DE++ A+ T+SGKL+R + Y G L Sbjct 649 GLPPDEIVLAPPRAVLKTSSGKLRRGDTRERYLAGRL 685 >gi|224824125|ref|ZP_03697233.1| AMP-dependent synthetase and ligase [Lutiella nitroferrum 2002] gi|224603544|gb|EEG09719.1| AMP-dependent synthetase and ligase [Lutiella nitroferrum 2002] Length=914 Score = 208 bits (530), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 162/534 (31%), Positives = 249/534 (47%), Gaps = 45/534 (8%) Query 33 ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREA 92 I Y++L A L + GE + + T L +L+ F+G+ML G +PVPI P Sbjct 128 IRYRELFEAGRAIAGGLAARGVTPGETIALMLPTGLGYLASFIGVMLAGGIPVPIYPPTR 187 Query 93 LKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQF-GRAT 151 L + + R +L + V++ T Q L A G T Sbjct 188 LSQLDEHLRRHARILNNAAVVLMI------------TTQQAKPVATLLRANVASLAGAVT 235 Query 152 AQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGD 211 ++LA T + A++QYTSGST P+GV++++ NLL+N+RAM D Sbjct 236 TEELAGETDRRPFQGTSSELAFLQYTSGSTGDPKGVMLSHANLLANIRAMGQVIGITAED 295 Query 212 VMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNF 271 V SWLPL+HDMGL+G+ +L++ V FL P +L+ ++ AT + PNF Sbjct 296 VGVSWLPLYHDMGLIGAWLGSLYHGCPLVLLPTLSFLAQPARWLQAVSRHHATLSGAPNF 355 Query 272 ALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGY 331 A E + A ++++G+DL R +EPV + RFAA FA G TAL Y Sbjct 356 AYE--LCARKTADSELQGLDLSHWRFAFNGAEPVSPATLERFAARFAPCGFQRTALTPVY 413 Query 332 GLAEATVAVSMSAPNTG----------FRT--------ETHAAAEVVTGGRVLPGYEVRI 373 GLAE+TVA++ G F T + HAA + + GR LP +E+RI Sbjct 414 GLAESTVALAFPPLGRGPLIDLIAAEPFATSGQALPAQDDHAALRIPSCGRPLPNHEIRI 473 Query 374 -----DAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILG 428 P + G ++ RG S Y AL +G+ D+ D ++ + E+ + G Sbjct 474 VGEDGSELPERQVGRLEFRGPSATRGYYHNPTASTALFHDGWLDSGDNAYMAEGEVYLTG 533 Query 429 RQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVLESPLDSII 482 R ++ I G N +PYD+E I + VA F +ER+VV+ E+ Sbjct 534 RVKDLIIRAGRNFYPYDLEEAIGNLPGIRKGCVAVFASADPHQGSERLVVLAETREQGSA 593 Query 483 DKAEADRLRCQVVA-ATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTL 535 + + +L Q A G+ LDE++ + T+SGK++R+A AY G + Sbjct 594 AREQLHQLIRQTAADVVGVPLDEIVLAPPHTVLKTSSGKIRRQACRAAYEQGMV 647 >gi|344341519|ref|ZP_08772438.1| AMP-dependent synthetase and ligase [Thiocapsa marina 5811] gi|343798639|gb|EGV16594.1| AMP-dependent synthetase and ligase [Thiocapsa marina 5811] Length=926 Score = 207 bits (527), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 174/538 (33%), Positives = 246/538 (46%), Gaps = 45/538 (8%) Query 30 SEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPI-P 88 ++ ISY+ L AA L+ L+ G V + T ++ + F G+++ G VPVPI P Sbjct 139 AQRISYRSLADGAARVAARLQAAGLRPGSTVALMLPTGSDYFNSFFGVLMAGGVPVPIYP 198 Query 89 PREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFG 148 P + E L RH R+L A A ++ R + G Sbjct 199 PSRPQQIEEH-------LRRHARILDNAGATFLITVPEARAIGRVLRVQVRSLRGIVTLE 251 Query 149 RATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQ 208 + ++T P D A++QYTSGST P+GVV+T+ +LL+N+RAM Q Sbjct 252 GLEQETPSETRARPAP----QDIAFLQYTSGSTGDPKGVVLTHADLLANIRAMGEVVQVA 307 Query 209 HGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFM 268 DV SWLPL+HDMGL+G+ +L+ + V +P FL P+ +L + G T + Sbjct 308 PDDVFVSWLPLYHDMGLIGAWLGSLYYGIPLVSMSPLAFLARPVRWLEAIHRHGGTISAA 367 Query 269 PNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALG 328 PNFA E + A I +DL + R + +EPV E +RRFAA FA GL AL Sbjct 368 PNFAYELCLTRIT--DAQIADLDLSRWRWALNGAEPVSPETLRRFAARFAPAGLRSEALA 425 Query 329 SGYGLAEATVAVSMSAPNTGFRT-------------------ETHAAAEVVTGGRVLPGY 369 YGLAEA V ++ G R E A EVV GR LPGY Sbjct 426 PVYGLAEAAVGLAFPPAGRGPRIDCIDRDRFARAGYALPVGCEDPQAMEVVACGRALPGY 485 Query 370 EVR-IDAA----PGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEI 424 VR +D A P G ++ +G S Y AL +G+ T D +L +I Sbjct 486 RVRVVDEAGRERPERHEGLLEFQGPSATRGYYRNPAATQALIRDGWHSTGDRAYLAGGDI 545 Query 425 VILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------NERVVVVLESP- 477 + GR ++ I G N +PY++E + + V F +ER+V++ ES Sbjct 546 HLTGRVKDLIIRGGRNIYPYEVEEALGKVDGVRKGCVVAFAALDPELGSERLVILAESKE 605 Query 478 LDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTL 535 D A RLR + GL DEL+ V A+ T+SGKL+R A Y G L Sbjct 606 RDPARRAELARRLRERATDVLGLPPDELLLVPPRAVLKTSSGKLRRAATRDRYLAGRL 663 >gi|167567182|ref|ZP_02360098.1| AMP-binding domain protein [Burkholderia oklahomensis EO147] Length=693 Score = 207 bits (526), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 172/547 (32%), Positives = 255/547 (47%), Gaps = 54/547 (9%) Query 33 ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREA 92 ++Y +L RA+ LR + G+ V + T L++ F ++ GA+PVPI P Sbjct 149 LTYGELYRRASDMASGLRERGIDPGDTVALMLPTGLDYFVSFAAILFCGAIPVPIYPPAN 208 Query 93 LKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATA 152 L + + R P+L + R+ R A S I++ L + + T Sbjct 209 LAQLDEHVGRHTPILENARIKALI-----AFRPAVS----IAQLLKLRVSTLQHV--LTP 257 Query 153 QQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDV 212 +Q+A A DD A +QYTSGST P+GV++++ NLL+N+RAM + DV Sbjct 258 EQIAGRAHLPPFRAAADDVALLQYTSGSTGTPKGVMLSHANLLANIRAMGDRMRVDASDV 317 Query 213 MGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFA 272 + SWLPL+HDMGL+G+ A L+ + A+ +P FL P +LR ++ T T PNFA Sbjct 318 LVSWLPLYHDMGLIGAWLAPLYFGIPAIVMSPVVFLARPALWLRAISRYRGTITAAPNFA 377 Query 273 LEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYG 332 E A H + DL +R +EPV+ + +R FAA FA G AL YG Sbjct 378 YERC--ARHLAALEPTEFDLSSLRFAFCGAEPVNPDTLRAFAARFASCGFDARALTPVYG 435 Query 333 LAEATVAVSMSAPNTGFRTETHAAAEVVTGGRVLP------------------GYEVRID 374 LAE T+ ++ AP G R + A + GR P G E+RI Sbjct 436 LAENTLGLTFPAPALGLRVDRVAREPLSASGRATPAPGDANALDVPSCGYPLDGTELRI- 494 Query 375 AAPGAR------AGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILG 428 G R G I+ RG S Y + L + + DT DLG++ D E+ I G Sbjct 495 VDDGEREVAERQVGRIEFRGTSATRGYYRNPAQTARLFHDSWRDTGDLGYVADGELYITG 554 Query 429 RQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVA-CFGVN-----ERVVVVLESPLDSII 482 R ++ I G++ FPY++E I VA C G + ERVV+++ES Sbjct 555 RAKDMIIRGGQHFFPYELEEAIERLPGAVTGGVAVCGGADPVSGTERVVILVES---DAT 611 Query 483 DKAEADRLRCQVVAAT----GLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRD--GTLP 536 D A +RLR V T G+ +++ V I T SGK++ A + + G LP Sbjct 612 DDAVCERLRASVNDVTAALWGMPAEQVSIVAPHGILKTPSGKIRHAATLEKFERHAGRLP 671 Query 537 RLATHAW 543 + A +W Sbjct 672 Q-APASW 677 >gi|89900929|ref|YP_523400.1| AMP-dependent synthetase and ligase [Rhodoferax ferrireducens T118] gi|89345666|gb|ABD69869.1| AMP-dependent synthetase and ligase [Rhodoferax ferrireducens T118] Length=958 Score = 207 bits (526), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 167/552 (31%), Positives = 253/552 (46%), Gaps = 50/552 (9%) Query 20 DRTLTITCEDSEV---ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLG 76 DR L E+ + + Y +L A A LR L L +G+ V I T EF + F G Sbjct 155 DRVLITLYENGDQAVDLRYAELHREAVALAAGLRALGLDKGDKVAIMLPTGREFFAAFFG 214 Query 77 LMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRF 136 + G VPVP+ P E + R+ ++R+ + + E A Q+ R Sbjct 215 TLYAGLVPVPLYPPARPSQLEDHLKRIAAIVRNAQARVLVTVER------AKPLSQLLR- 267 Query 137 TALAEAGDEQFGRATAQ-QLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLL 195 A+A QF R A LAD P T D A++QYTSGST P+GV++T+ NLL Sbjct 268 ---AQAEALQFVRTVADLSLADAPRMQ-PALTASDIAFLQYTSGSTGDPKGVILTHANLL 323 Query 196 SNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFL 255 +N+RAM SQ D SWLPL+HDMGL+G+ AL+ V +P FL P +L Sbjct 324 ANLRAMWRASQVGSSDTFVSWLPLYHDMGLIGACLGALYLGFHLVLMSPLAFLARPARWL 383 Query 256 RLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAA 315 + T + PNFA E ++ A++ G+DL R +EPV + + RFAA Sbjct 384 ETIHRHRGTVSAAPNFAYELCLSKLT--DAELAGLDLSCWRLAFNGAEPVSPDTLERFAA 441 Query 316 TFAGVGLAPTALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAA 356 FA AL YGLAE TV ++ G R + A Sbjct 442 RFAPCSFKREALTPVYGLAENTVGLAFGPVGRGPLVDRVDRAALARDGVAEPARPDDAQA 501 Query 357 AEVVTGGRVLPGYEVRIDAA-----PGARAGTIKLRGDSVAAKAYVGGKKLDALDEEG-F 410 +V+ G LPG+E+R+ A P G ++ RG S + + Y+ + +G + Sbjct 502 LRIVSCGSPLPGHELRVVGAGGRELPEREQGRVQFRGPS-STQGYLNNPVANQRLLDGDW 560 Query 411 CDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV---- 466 +T DLG++ E+ + GR+ ++ I G N P ++E + + + VA F Sbjct 561 LNTGDLGYIAAAELFLTGREKDIIIRGGFNIHPQELESAVANIAGVRKGGVAVFAATDRR 620 Query 467 --NERVVVVLESPLDSIIDKAEADRLRCQVVAA-TGLQLDELITVRRGAIPTTTSGKLKR 523 ER+VV+ E+ + +A+ R + A G D+++ ++ T+SGK +R Sbjct 621 SGTERLVVLAETRVREPAQRAQMIRAITALSATLLGAPADDVVLAPPRSVLKTSSGKTRR 680 Query 524 RAVAQAYRDGTL 535 A + Y G L Sbjct 681 AACRELYEQGRL 692 >gi|121595383|ref|YP_987279.1| AMP-dependent synthetase and ligase [Acidovorax sp. JS42] gi|120607463|gb|ABM43203.1| AMP-dependent synthetase and ligase [Acidovorax sp. JS42] Length=653 Score = 206 bits (525), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 179/563 (32%), Positives = 266/563 (48%), Gaps = 67/563 (11%) Query 16 SACTDRTLTITCEDSE--VISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSC 73 +A DR +T+ D E V+S+Q L RA A + L+R + G+ +++ N FL Sbjct 13 TARDDRQITLIEGDKEQRVLSFQRLRQRALAVLGALQRQSIAPGDTMILCLADNERFLEM 72 Query 74 FLGLMLHGAVPVPIPP------REALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAA 127 F +L G VPVP+ P R+ L R +LGP + + T E + AAA Sbjct 73 FWACVLGGIVPVPLAPGATDAHRQKLL---RVFAQLGP--KASVYIDRTSLERLDGFAAA 127 Query 128 S--TDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPR 185 D + G G Q ++ DD A++QY+SGST P+ Sbjct 128 QGLADQAAALRARALVPGGLDIGGEPGQPVSPRP---------DDLAFIQYSSGSTGEPK 178 Query 186 GVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPH 245 GV++T+RNL +N+ A+ + F DV SW+PL HDMGL+G L S Sbjct 179 GVLLTHRNLCANIAAIIEAAAFSDRDVALSWMPLSHDMGLIGFHLNMLACGASHAIMRTD 238 Query 246 RFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPV 305 F PL +L + AT PNF + + + + +G+DL +R + +EP+ Sbjct 239 LFARRPLLWLDQASQRRATVLCSPNFGYQHYLRQFALKPP--QGLDLSAVRLIFNGAEPI 296 Query 306 HAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRT-------------- 351 A+ RRF A GL P A+ YGLAEA++AVS P+T T Sbjct 297 SADLCRRFTQAMAPHGLQPNAMFPVYGLAEASLAVSFPPPSTPLETIELDRTALRVGAPV 356 Query 352 ------ETHAAAEVVTGGRVLPGYEVRI--DAAPGA---RAGTIKLRGDSVAAKAYVGGK 400 TH A E V GR +PG E+RI DA G G +++RGD+V+ Y + Sbjct 357 RAAAPGSTH-AIEFVKLGRAVPGCEIRIVDDAGTGLADRTVGHVQIRGDNVSG-GYFRDR 414 Query 401 KLDALDE--EGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHR 458 + G+ DT DLG ++D ++VI GR ++ IV+G+N +P D+E I + Sbjct 415 SGNGASRVTPGWLDTGDLGVMLDGQLVITGRAKDLIIVNGQNYYPTDLEEIAQQVPGIEA 474 Query 459 TKVACFGVNE--------RVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRR 510 +VA GV + + V+ L + K +A LR + T L+L+ ++ V Sbjct 475 NRVAAVGVRDASEGTESVALFVIHRGDLAGFVPKVQA--LRRIIGQQTDLELNHIVPV-- 530 Query 511 GAIPTTTSGKLKRRAVAQAYRDG 533 AIP TTSGKL+R A+A A+ G Sbjct 531 SAIPKTTSGKLQRYALALAFEQG 553 >gi|167572594|ref|ZP_02365468.1| AMP-binding domain protein [Burkholderia oklahomensis C6786] Length=934 Score = 206 bits (524), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 175/571 (31%), Positives = 259/571 (46%), Gaps = 59/571 (10%) Query 33 ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREA 92 ++Y +L RA+ LR + G+ V + T ++ F ++ GA+PVPI P Sbjct 136 LTYGELYRRASDMASGLRERGIDPGDTVALMLPTGFDYFVSFAAILFCGAIPVPIYPPAN 195 Query 93 LKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATA 152 L + + R P+L + R+ A + A ++S + T Sbjct 196 LAQLDEHVGRHTPILENARIKALI-AFRPAVSIAQLLKLRVSTLQHVL----------TP 244 Query 153 QQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDV 212 +Q+A A DD A +QYTSGST P+GV++++ NLL+N+RAM + DV Sbjct 245 EQIAGRAHLPPFRAAADDVALLQYTSGSTGTPKGVMLSHANLLANIRAMGDRMRVDASDV 304 Query 213 MGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFA 272 + SWLPL+HDMGL+G+ A L+ + A+ +P FL P +LR ++ T T PNFA Sbjct 305 LVSWLPLYHDMGLIGAWLAPLYFGIPAIVMSPVVFLARPALWLRAISRYRGTITAAPNFA 364 Query 273 LEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYG 332 E A H + DL +R +EPV+ + +R FAA FA G L YG Sbjct 365 YERC--ARHLAALEPTEFDLSSLRFAFCGAEPVNPDTLRAFAARFASCGFDARVLTPVYG 422 Query 333 LAEATVAVSMSAPNTGFRTETHAAAEVVTGGRVLP------------------GYEVRID 374 LAE T+ ++ AP G R + A + GR P G E+RI Sbjct 423 LAENTLGLTFPAPALGLRVDRVAREPLSASGRATPAPGDANALDVPSCGYPLDGTELRI- 481 Query 375 AAPGAR------AGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILG 428 G R G I+ RG S Y + L + + DT DLG++ D E+ I G Sbjct 482 VDDGEREVAERQVGRIEFRGTSATRGYYRNPTQTARLFHDSWRDTGDLGYVADGELYITG 541 Query 429 RQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVA-CFGVN-----ERVVVVLESPLDSII 482 R ++ I G++ FPY++E I VA C G + ERVV+++ES Sbjct 542 RAKDMIIRGGQHFFPYELEEAIERLPGAVTGGVAVCGGADPVSGTERVVILVES---DAT 598 Query 483 DKAEADRLRCQV----VAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRD--GTLP 536 D A +RLR V A G+ +++ V I T SGK++ A + + G LP Sbjct 599 DDAACERLRASVNDVTAALWGMPAEQVSIVAPHGILKTPSGKIRHAATLEQFERHAGRLP 658 Query 537 RLATHAWTADPD-----SAPKTTRSSLEGAH 562 + A +W D AP R+S AH Sbjct 659 Q-APASWRQFADLAAGSVAPFGRRASRRAAH 688 >gi|296170910|ref|ZP_06852447.1| AMP-binding protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894459|gb|EFG74203.1| AMP-binding protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=933 Score = 204 bits (520), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 182/579 (32%), Positives = 263/579 (46%), Gaps = 58/579 (10%) Query 2 TAALLSPAIAWQQISACTDRT-LTIT-----CEDSEVISYQDLIARAAACIPPLRRLDLK 55 +A L+ + W + A DRT L I D ++Y L AAA L D+ Sbjct 111 SALTLNDVLNWH-VGATPDRTHLRILDDAGGAPDGADMTYSALHRGAAAVASGLIAHDVM 169 Query 56 RGEPVLITAHTNLEFLSCFLGLMLHGAVPVPI-PPREALKTTERFMTRLGPLLRHHRVLI 114 G+ V I T E+ F G+ L GAVPVP+ PP + + G L ++ Sbjct 170 PGQAVAIMLPTCREYFVTFAGVALAGAVPVPVYPPSRPSQLADHLRRTAGILANAGATML 229 Query 115 CTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYV 174 T E + ++ + R +AE T + + AT P D A V Sbjct 230 VTVPEAVTLGHLLRSNVESLRHVVVAE---------TLTRAGEHATTPLPRPRAGDLALV 280 Query 175 QYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALF 234 QYTSGST P+GV +T+ NLL+N+RAM + D SWLPL+HDMGL+G+ ++ Sbjct 281 QYTSGSTGQPKGVALTHHNLLANIRAMGRAAAATGADTFVSWLPLYHDMGLIGAWLGCMY 340 Query 235 NSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHK 294 V V +P FL P +L + + A+ + PNFA E ++ R +IEG+DL Sbjct 341 FGVPLVVMSPQAFLMRPSRWLWAIHDNRASMSAGPNFAYELCLSKI--RDDEIEGLDLSC 398 Query 295 MRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTG------ 348 R +EPV A + RF FA G A+ YGLAE++V ++ G Sbjct 399 WRLAYNGAEPVSAATIERFGDRFAPYGFRREAMTPVYGLAESSVGLAFPPLGRGPLIDRI 458 Query 349 --------FRTETHAAAE----VVTGGRVLPGYEVRIDAAPGA-----RAGTIKLRGDSV 391 R E E V GR LPG+E+RI A G R G ++ RG S Sbjct 459 RRDAFARSGRAEPARPGERDLRFVACGRPLPGHEIRILDAAGNELGDRREGRVEFRGPSA 518 Query 392 AAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIR 451 A + AL + DT DLG+ V+ ++ + GR +V I G N P ++E + Sbjct 519 TAGYFNNPAATRALFHGDWLDTGDLGYTVEADLYVTGRIKDVIIRAGRNLHPAELEEAVG 578 Query 452 GESEQHRTKVACF------GVNERVVVVLESPLDSIIDKAEADRLRCQVVAAT----GLQ 501 + VA F G ER+VV+ E+ +I D A A LR ++ +AT G+ Sbjct 579 NIGGVRKGCVAVFASPDPSGGPERLVVLAET--RAIRDDARAA-LRSEIASATVDLLGVA 635 Query 502 LDELITVRRGAIPTTTSGKLKR---RAVAQAYRDGTLPR 537 DE++ + T+SGK++R R + QA R G PR Sbjct 636 PDEVVLAPPRTVLKTSSGKIRRAASRGLYQAGRIGARPR 674 >gi|71068219|gb|AAZ23074.1| acyl-CoA ligase [Streptomyces fradiae] Length=732 Score = 204 bits (519), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 176/553 (32%), Positives = 258/553 (47%), Gaps = 78/553 (14%) Query 34 SYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHG--AVPVPIPPRE 91 ++ D AR A + LR L+ G VL+ + EF + + G + G AVP P+P Sbjct 93 AWLDDTARRIAVL--LRAAGLETGARVLLLFPQSAEFAAAYAGCLYAGMVAVPAPLP--- 147 Query 92 ALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAG-------D 144 T R+ V I +E + + T+ + ++ A G D Sbjct 148 --TGTSHEAARV--------VGIAKDSEAGAVLTVSETEADVRQWAARTGLGALPLHCVD 197 Query 145 EQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVG 204 E G A D T P D A +QYTSGST +P+GVV+T+ L N+R++ G Sbjct 198 ELPGDA------DPDTWREPEIRADTVAVLQYTSGSTGSPKGVVVTHGALADNVRSLLTG 251 Query 205 SQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGAT 264 G +G WLP++HDMGL G L ALF+ +AV + FL P +LRL+ G Sbjct 252 FDLGSGARLGGWLPMYHDMGLFGLLSPALFSGGAAVLMSGSAFLRRPSQWLRLIDRFGLV 311 Query 265 HTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAP 324 + P+FA ++ + R + +G+DL + R SEP+ AE +R FA FA GL P Sbjct 312 FSAAPDFAYDYCVRRV--RPEETDGLDLSRWRWAANGSEPIRAETLRAFAKEFAPAGLHP 369 Query 325 TALGSGYGLAEATVAVSMSAPNTGFRT--------ETH---------AAAEVVTGGRVLP 367 A YGLAEAT+ VS+ P RT E H + E+V+ GR P Sbjct 370 NATTPCYGLAEATLLVSL--PTGELRTRRVDVAELENHRFVEAAVGRPSREIVSCGRP-P 426 Query 368 GYEVRI------------DAAPGARAGTIKLRGDSVAAKAYVGGKKLDA----LDEEG-- 409 E+R+ D A R G I++RG SV A+ Y + A +D +G Sbjct 427 SLEIRVVDPATGKSVTGGDGAGETRVGEIRVRGASV-ARGYWQKPEATAETFVMDADGSG 485 Query 410 -FCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNE 468 + T DLG L + E+ + GR E+ IVHG N +P+DIE +R + A F ++ Sbjct 486 PWLRTGDLGALYEGELYVTGRIKELLIVHGRNIYPHDIEHELRARHAELGAVGAAFSLST 545 Query 469 RV--VVVLESPLDSIIDKAEADR----LRCQVVAATGLQLDELITVRRGAIPTTTSGKLK 522 VVV+ ++ + + LR + GL ++ VRRG IP T+SGK++ Sbjct 546 ESGEVVVVTHEVNPTVRPEQGPELVTALRATLAREFGLAPAGVVLVRRGRIPRTSSGKVQ 605 Query 523 RRAVAQAYRDGTL 535 RR A+ + G L Sbjct 606 RRLTARLFSTGEL 618 >gi|82701365|ref|YP_410931.1| acyl-CoA synthetase [Nitrosospira multiformis ATCC 25196] gi|82409430|gb|ABB73539.1| AMP-dependent synthetase and ligase [Nitrosospira multiformis ATCC 25196] Length=608 Score = 204 bits (519), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 170/535 (32%), Positives = 252/535 (48%), Gaps = 52/535 (9%) Query 32 VISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPRE 91 V+ YQ L A L RL L RG+ V I A T EF+ F G VP +P Sbjct 73 VLPYQALRQNAQTAARQLLRLGLARGDRVAIIADTTPEFVEIFYACRYAGLVPYAMPVPV 132 Query 92 ALKTTERFMTRLGPLLRHHRV-LICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGR- 149 L + ++ +L +L + A++ + A+ Q R+ E Q G Sbjct 133 NLGSHAVYVRQLRGMLEAGQASAALANADYVDFLKEAAEGSQYLRWVGTPE----QLGEL 188 Query 150 -ATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAV-GSQF 207 A+ +LA + D+ AY+Q+TSGST PRGVVIT L+SN++ + G Sbjct 189 PASITELAPNSP--------DEIAYLQFTSGSTRMPRGVVITEGALMSNLQGIVRHGLNI 240 Query 208 QHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTF 267 + GD SWLP +HDMGLVG + A + VS + F PL +LRL++ + AT F Sbjct 241 RAGDRCASWLPFYHDMGLVGMVMAPMVAQVSVDYLATRDFAIRPLQWLRLISRNRATVAF 300 Query 268 MPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTAL 327 F L+ + R +D+E +DL R + +E + + +R FA FA G A Sbjct 301 SQPFGLK--LCTLRVRDSDLEDLDLSSWRAAGVGAEMIRPDTLRNFAEKFAPAGFDARAF 358 Query 328 GSGYGLAEATVAVSMSAPNTGFRT-------------------ETHAAAEVVTGGRVLPG 368 YGLAE+T+AV+ S GF++ E +E V GR LPG Sbjct 359 LPCYGLAESTLAVTFSEVGQGFQSLRVDAATLVDRKMAVRLQVEGRKYSEFVNCGRALPG 418 Query 369 YEVR-IDAA----PGARAGTIKLRGDSVAAKAYVGGKKL-DALDEEGFCDTHDLGFLVDD 422 + V+ ID A P R G++ ++G S+ + + L + DT DLGFL + Sbjct 419 HIVKVIDEAGQQLPDLRVGSVLVQGSSIMTGYFNNPEDTGKTLKPGNWLDTGDLGFLFEG 478 Query 423 EIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNE-----RVVVVLESP 477 ++ I GR+ +V IV+G N DIE + + E + + FG+ + +V+V+E Sbjct 479 DLYITGRRTDVIIVNGRNIRAQDIEELAEQQPEVRTREASAFGITDANDVTTIVLVIECR 538 Query 478 LDSIIDKAE-ADRLRCQVVAATGLQ-LDELITVRRGAIPTTTSGKLKRRAVAQAY 530 L SI D+ RL+ V A G+ L EL+ +P T+SGKL R A Q + Sbjct 539 LTSITDRQSLTSRLQRLVYMAFGVNCLVELVPPH--TLPRTSSGKLSRFAARQGF 591 >gi|52842442|ref|YP_096241.1| saframycin Mx1 synthetase B [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] gi|52629553|gb|AAU28294.1| saframycin Mx1 synthetase B [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Length=581 Score = 204 bits (519), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 161/563 (29%), Positives = 256/563 (46%), Gaps = 73/563 (12%) Query 28 EDSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPI 87 E E ++Y+ L A A L+ K G+ VL+ L + FLG + G + VPI Sbjct 34 ELEETMTYEQLDQHAKAIAATLQAEGAKPGDRVLLLFAPGLPLIQAFLGCLYAGCIAVPI 93 Query 88 PP---REALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGD 144 P + L +R +T P V++ A+H I +FTA + Sbjct 94 YPPAQEKLLDKAQRIVTNSKP------VIVLMIADH------------IKKFTADELNTN 135 Query 145 EQFGRATA---QQLADTATADWPLCTL--DDDAYVQYTSGSTAAPRGVVITYRNLLSNMR 199 +F + A + + ++ W ++ +D A++QYTSGST P+GV++++ NLL N+ Sbjct 136 PKFLKIPAIALESIELNRSSSWQPTSIKSNDIAFLQYTSGSTMHPKGVMVSHHNLLDNLN 195 Query 200 AMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLT 259 + ++ SWLP HHDMGL+G + ++ + A+ +P FL +PL +L+ +T Sbjct 196 KIFTSFHMNDETIIFSWLPPHHDMGLIGCILTPIYGGIQAIMMSPFSFLQNPLSWLKHIT 255 Query 260 SSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAG 319 AT + PNFA ++ + R EG+DL +EPV E M F F Sbjct 256 KYKATISGSPNFAYDYCVKRI--REEKKEGLDLSSWVTAFNGAEPVREETMEHFYQAFKE 313 Query 320 VGLAPTALGSGYGLAEATVAVSMSAPNTGFRTET-----------HAAAEVVTGGRVL-- 366 G A YGLAEAT+ V+ P + ++T T H A + G L Sbjct 314 FGFRKEAFYPCYGLAEATLLVTGGTPGSSYKTLTLAKEQFQDHRVHFADDNSPGSYKLVS 373 Query 367 ---PGYEVRIDAAPGA-------RAGTIKLRGDSVAAKAY----------VGGKKLDALD 406 P EV+I P + G I ++ +SVA K Y GK D Sbjct 374 SGNPIQEVKI-IDPDTLIPCDFDQVGEIWVQSNSVA-KGYWNQPEETRHAFAGKIKDDER 431 Query 407 EEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRT-KVACFG 465 + T DLGFL ++E+ + GR ++ I++G+N +P DIEF + H K A F Sbjct 432 SAIYLRTGDLGFLHENELYVTGRIKDLIIIYGKNHYPQDIEFSLMHSPLHHVLGKCAAFV 491 Query 466 VNE----RVVVVLESPLDSIIDKAEADRLRCQVVAAT----GLQLDELITVRRGAIPTTT 517 + E ++ V+ E + +D D L ++ L++ ++ + A+P TT Sbjct 492 IQEEHEYKLTVMCEVK-NRFMDDVAQDNLFNEIFELVYENHQLEVHTIVLIPLKAMPHTT 550 Query 518 SGKLKRRAVAQAYRDGTLPRLAT 540 SGK++R + D TLP +AT Sbjct 551 SGKIRRNFCRKHLLDKTLPIVAT 573 >gi|182678861|ref|YP_001833007.1| AMP-dependent synthetase and ligase [Beijerinckia indica subsp. indica ATCC 9039] gi|182634744|gb|ACB95518.1| AMP-dependent synthetase and ligase [Beijerinckia indica subsp. indica ATCC 9039] Length=947 Score = 203 bits (517), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 159/545 (30%), Positives = 252/545 (47%), Gaps = 49/545 (8%) Query 23 LTITCEDSEVI---SYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLML 79 +T+ +DS ++ SY L A+A L D+ G+ V + T++EF F ++ Sbjct 145 ITLLQDDSTILDQLSYGRLAAQARQIARGLIARDIGPGDRVALMLPTSIEFFCAFFAILY 204 Query 80 HGAVPVPIPPREALKTTERFMTRLGPLLRH--HRVLICTPAEHDEIRAAASTDCQISRFT 137 GAVPVPI P E + R +L + R+LI P + + AA Q+S Sbjct 205 VGAVPVPIYPPMRPSQIEDHLRRQAGILNNAGSRMLITMP---EGLSVAALLRAQLSELE 261 Query 138 ALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSN 197 ++A E A +L +T P+ T A +QYTSGST P+GV++++ NLL+N Sbjct 262 SVASVA-ELMAEAGDMRLPPAST---PVST----ALIQYTSGSTGDPKGVILSHANLLAN 313 Query 198 MRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRL 257 ++AM + DV SWLPL+HD+GL+G+ F L+ +P FL P +L Sbjct 314 VKAMGAALEANSADVFVSWLPLYHDLGLIGAWFGCLYFGAPLYVMSPLSFLVRPESWLWA 373 Query 258 LTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATF 317 + AT + PNF E + A + G+DL +R + +EPV +RRF F Sbjct 374 IHRFRATLSAAPNFGFE--LCTAKIDTAHLTGLDLSSLRAVANGAEPVSPYTLRRFTEKF 431 Query 318 AGVGLAPTALGSGYGLAEATVAVSMSAPNTG-------------------FRTETHAAAE 358 A G P + YGLAE V ++ S G + E Sbjct 432 AAFGFRPEVMMPVYGLAENAVGLAFSTLGRGPLIDRIDRNALMSRGVAEPAKANDQNPLE 491 Query 359 VVTGGRVLPGYEVRIDAAPG-----ARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDT 413 +V GR LPG+E+RI G + G ++ RG S + + K L +G+ D+ Sbjct 492 LVACGRPLPGHEIRIVDPAGHEIGDRQEGRLEFRGPSATSGYFCNEAKTRDLIHDGWLDS 551 Query 414 HDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGV------N 467 D ++ + ++ I GR ++ I G + +P +IE I R VA FG+ Sbjct 552 GDRAYMAEGDVYITGRIKDIIIRAGRHIYPQEIEDAIATIPGIRRGSVAVFGMTDRVSGT 611 Query 468 ERVVVVLESPLDSIIDKAEADRLRCQVVAAT-GLQLDELITVRRGAIPTTTSGKLKRRAV 526 ER+V+V E+ + E + ++ +A G DE++ +P T+SGK++R A Sbjct 612 ERLVIVAETRETDPAARHEIETRAHELTSAICGTPPDEVVLAPPRTVPKTSSGKIRRSAT 671 Query 527 AQAYR 531 + Y+ Sbjct 672 RELYQ 676 >gi|296445080|ref|ZP_06887041.1| AMP-dependent synthetase and ligase [Methylosinus trichosporium OB3b] gi|296257501|gb|EFH04567.1| AMP-dependent synthetase and ligase [Methylosinus trichosporium OB3b] Length=934 Score = 202 bits (514), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 154/524 (30%), Positives = 234/524 (45%), Gaps = 49/524 (9%) Query 53 DLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHH-- 110 D++ G+ + + T L+F F ++ GAVPVPI P L E + R +LR+ Sbjct 164 DIEAGDRIALMLPTGLDFFVAFFAVLYAGAVPVPIYPPMRLSQIEDHLRRQIGILRNAGV 223 Query 111 RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDD 170 ++LI P + +R A +G R + Sbjct 224 KMLITAP--------------EAARLAGFARSGAPTLERIVVVADLEATGELAATPAGAA 269 Query 171 DAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLF 230 A +QYTSGST P+GVV+++ NLL+N+RAM DV SWLPL+HDMGL+G+ F Sbjct 270 TAMLQYTSGSTGDPKGVVLSHANLLANIRAMGAALAASSADVFVSWLPLYHDMGLIGAWF 329 Query 231 AALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGI 290 L+ +P FL P +L + + T + PNFA E ++ +++EG+ Sbjct 330 GCLYFGAPLYVMSPLTFLARPSAWLSAIHAHRGTLSAAPNFAFELCLDKID--ASELEGL 387 Query 291 DLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATV------------ 338 DL +R + +EPV A +RRF F G P A+ S YGLAE V Sbjct 388 DLSSLRFVANGAEPVGARTIRRFTQRFGPHGFRPEAMASVYGLAENAVGLAFPPLARAPL 447 Query 339 -------AVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPG-----ARAGTIKL 386 A+++ A E+V G+ LPG+E+RI A G R G ++ Sbjct 448 IDRVDRDALTLRGEAAPAAPGDAGALEIVACGQPLPGHEIRIVDAAGRELGERREGRLEF 507 Query 387 RGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDI 446 RG S A + K L +G+ D+ D ++ ++ + GR ++ I G + +P +I Sbjct 508 RGPSATAGYFRNEAKTRELIRDGWLDSGDRAYMAGGDVFVTGRVKDILIRAGRHLYPQEI 567 Query 447 EFIIRGESEQHRTKVACFGV------NERVVVVLESPLDSIIDKAEADRLRCQVVAAT-G 499 E I + VA FGV ER+VVV E+ +A + + ++A G Sbjct 568 EAAIGDIDGIRKGCVAVFGVPDPRSGTERIVVVAETYATETGARAALEAKAQEAMSAIGG 627 Query 500 LQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAW 543 DE++ V P T+SGK++R A Y G L W Sbjct 628 TPADEIVLVPPRTTPKTSSGKIRRSAARDLYLRGRLGAAPRAVW 671 >gi|86740633|ref|YP_481033.1| AMP-dependent synthetase and ligase [Frankia sp. CcI3] gi|86567495|gb|ABD11304.1| AMP-dependent synthetase and ligase [Frankia sp. CcI3] Length=648 Score = 201 bits (512), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 180/569 (32%), Positives = 250/569 (44%), Gaps = 74/569 (13%) Query 31 EVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIP-P 89 EVIS +DL A + L ++ GE V + A + EFL + GA P+P P Sbjct 90 EVISLRDLAATSRIIAAALTTDGVQAGERVGVLAANSAEFLLALFAISRAGAAACPLPLP 149 Query 90 REA--LKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQF 147 A L ++R HRV+ R +A R L Sbjct 150 TTAHDLNGYADRVSRTTAAAGIHRVVTGG-------RVSAILRRTADRLGGLRFLPAADL 202 Query 148 GRATAQQLADTATADWPLCTL--------DDDAYVQYTSGSTAAPRGVVITYRNLLSNMR 199 R P C + DD A VQ+TSGSTAAP+GVV+++R +L +R Sbjct 203 VRDVGPATPTRQPHPGPECPVGAVGAVGADDVAIVQFTSGSTAAPKGVVLSHRAVLCGIR 262 Query 200 AMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLT 259 A+ G + GD G WLPL HDMGL +L +A+ + +P F+ DP G+LR Sbjct 263 AIIDGIRLGEGDHGGIWLPLFHDMGLFATL-SAIMTGIPMTVWSPADFVRDPAGWLRSFL 321 Query 260 SSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAG 319 +SGAT + PNFA + L+ A ++ G+D+ + R + +EPV A G+ RF FA Sbjct 322 ASGATISPAPNFAYDDLVRAIDPD--EVPGLDMRRWRVALNGAEPVSAVGVERFLDHFAP 379 Query 320 VGLAPTALGSGYGLAEATVAVSMS----APNTGFRTETHAAAE---------------VV 360 G APTA+ YG+AEAT+AV+ AP + AAE +V Sbjct 380 AGFAPTAMFPVYGMAEATLAVAFPPLGRAPVVTWVDRDRLAAEGIVTEVPREHPRAKGLV 439 Query 361 TGGRVLPGYEVRI--------------DAAPGARAGTIKLRGDSVAAKAYV-GGKKLDAL 405 GR + +RI AP R G I++RG SV + GG Sbjct 440 AVGRPVRDIRIRIADLHGDVLADPLGDGLAPSLRVGEIQIRGGSVTSGYLTAGGLTTGGF 499 Query 406 DEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFG 465 +G+ T DLGF D++ + GR E+ I+ G N +P D E +R HR +V FG Sbjct 500 TADGWLRTGDLGFQRGDDLFVTGRDKEMIIIRGVNYYPEDAEAAVRDLPGVHRRRVVAFG 559 Query 466 VNER------------------VVVVLESPLDSIIDKAE-ADRLRCQVVAATGLQLDELI 506 ++ V VV E+ L D+A A LR AA GL + Sbjct 560 SPDQPDAAGSPPDATGAKAAGGVTVVGETALTEPADRARLATDLRMAATAALGLSTVTVR 619 Query 507 TVRRGAIPTTTSGKLKRRAVAQAYRDGTL 535 V GA+P T+SGK +R AV G L Sbjct 620 LVEPGALPRTSSGKFQRLAVRDLVGRGVL 648 >gi|112791733|gb|ABI22131.1| putative non-ribosomal peptide synthetase [Streptomyces lavendulae] Length=1836 Score = 201 bits (511), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 172/545 (32%), Positives = 250/545 (46%), Gaps = 72/545 (13%) Query 59 PVLITAHTNLEFLSCFLGLMLHGAVPVPI-PPREALKTTERFMTRLGPLLRH--HRVLIC 115 PVL+ ++L FL + G P+ PP A R RLG +L L+ Sbjct 143 PVLLLMQPGPDYLKGFLATVYAGLPAAPVYPPNPA--DVRRDFIRLGAILAKLPDATLLT 200 Query 116 TPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADT-----ATADW--PLCTL 168 P + +R E E+ ++L DT A DW P Sbjct 201 EPGLLEPLR----------------ELFAERLPDVRPERLVDTSVPAGAEDDWRAPAVRP 244 Query 169 DDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGS 228 ++ ++Q+TSGST PRGV++++RNLL+N+RA+ WLP +HDMGLVG Sbjct 245 EEPLFIQFTSGSTGTPRGVLVSHRNLLANVRAITDRFGLDTSSTGALWLPPYHDMGLVGG 304 Query 229 LFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIE 288 + L + +P F+ DP+G+LRL++ +GATHT PNF + + R D+ Sbjct 305 VLTPLVSGFPIHLLSPLSFVSDPMGWLRLVSETGATHTGAPNFG--YALATRRARDEDVA 362 Query 289 GIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTG 348 +DL +++ +EPV A +R FA FA GL+P YGLAE+T+ VS P G Sbjct 363 ALDLSRLQVAFSGAEPVDASTLRAFAERFAPAGLSPDVFLPCYGLAESTLIVSGGRPGAG 422 Query 349 FRTET-----------------HAAAEVVTGGRVLPGYEVRI-DAAPGARAGTIKLRGDS 390 RT A E+V+ G V+ G EVRI D GA AG ++ Sbjct 423 LRTHRLDPEALALGRAEPARPGAPATELVSSGPVVAGTEVRIADPVTGAAAGPGEIGEVF 482 Query 391 VAAKAYVGGKKLD------------ALDEEGFCDTHDLGFL-VDDEIVILGRQDEVFIVH 437 VA+ + G D A + T DLGFL D ++V + R +V +V Sbjct 483 VASDSVAEGYFEDPEETARTFGATLAGSSRSWMRTGDLGFLGADGDLVPVARIKDVIVVR 542 Query 438 GENRFPYDIEFIIRGESEQHRTK-VACFGV-----NERVVVVLESPLDSIIDKAEADRLR 491 G N P DIE ++ R VA GV E ++VV E ++ D+A+A R+ Sbjct 543 GRNLHPQDIERTVQDTDPGIRKGCVAAAGVPGPDGGEEILVVAELRPEAADDEAQARRIA 602 Query 492 CQVVAATGLQLDELI----TVRRGAIPTTTSGKLKRRAVAQAYRDGTLPR-LATHAWTAD 546 +V AA + + +R +P T+SGK++R A A+ DG+L L A TA Sbjct 603 REVRAAVAREHSAPVRGIHLIRPSTLPKTSSGKVQRSAARAAHLDGSLATVLCDTADTAA 662 Query 547 PDSAP 551 P AP Sbjct 663 PTGAP 667 Score = 42.0 bits (97), Expect = 0.29, Method: Compositional matrix adjust. Identities = 19/36 (53%), Positives = 26/36 (73%), Gaps = 0/36 (0%) Query 164 PLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMR 199 PL T DD AY+ +TSGST P+GVVI +R ++ +R Sbjct 1365 PLTTPDDPAYLLFTSGSTGRPKGVVIPHRGPVNLIR 1400 >gi|54301694|ref|YP_131687.1| acyltransferase family protein [Photobacterium profundum SS9] gi|46915114|emb|CAG21887.1| hypothetical acyltransferase family protein [Photobacterium profundum SS9] Length=945 Score = 200 bits (509), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 161/551 (30%), Positives = 247/551 (45%), Gaps = 60/551 (10%) Query 33 ISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREA 92 ISY+ L A L + D++ G+ + I T+ ++ F G++ A+PVPI P Sbjct 154 ISYRALRDEALRIASGLVKQDVEPGQCIAIMLPTSNDYFYSFFGILFARAIPVPIYPPAR 213 Query 93 LKTTERFMTRLGPLLRHH--RVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRA 150 E + R +L++ R+LI P + Q+ A+ Sbjct 214 PSQIEDHLKRHARILQNSQVRILITVPEAKP---LSQLLRLQVPSIQAVV---------- 260 Query 151 TAQQLADTATADWPLCTLD----DDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQ 206 T +L A+ PL T D D A++QYTSGST P+GV +T+ NLL+N+R M Sbjct 261 TVPELRQAASG--PLSTGDAQSSDIAFLQYTSGSTGNPKGVALTHANLLANVRTMGRVVC 318 Query 207 FQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHT 266 DV SWLP++HDMGL+G+ F +L++++ V +P FL P +L + T + Sbjct 319 VDSTDVFVSWLPVYHDMGLIGTWFGSLYHAIPLVIMSPLLFLSKPQRWLWAIHHHRGTLS 378 Query 267 FMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTA 326 PNFA E IN A++EG+DL R +EPV +RRF FA G P Sbjct 379 PAPNFAYELCINKID--DAELEGLDLSTWRLSWNGAEPVSPSTIRRFTERFAKYGFRPET 436 Query 327 LGSGYGLAEATVAVSMSA-------------PNTGFRTETHAAA------EVVTGGRVLP 367 + YGLAE +V ++ P F AAA ++V G+ LP Sbjct 437 MSPVYGLAECSVGLTFPTSVRLPLIERIRREPMERFGRAITAAADETDVMQIVGLGQPLP 496 Query 368 GYEVRI-----DAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDD 422 G+++RI P G ++ +G S Y +K L + DT D F+V Sbjct 497 GHQIRIVDEFGRELPEREEGGLEFKGPSATQGYYRDPEKTQQLFHGEWLDTGDRAFMVGG 556 Query 423 EIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVN------ERVVVVLES 476 E+ I GR ++ I G N P+++E + + VA F + ER++V+ E+ Sbjct 557 ELFITGRSKDIIIRAGRNIHPHELEEAVCNIPGIRKGCVAAFASHDSHSGTERLIVLAET 616 Query 477 PLDSIIDKAEADRLRCQV----VAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRD 532 DK + RL+ +V + G DE++ +P T+SGK++R A Y Sbjct 617 ---RETDKVQQQRLQQEVNNLSLDLLGSPPDEVVIAPPHTVPKTSSGKIRRAACKDLYEQ 673 Query 533 GTLPRLATHAW 543 L W Sbjct 674 NKLDARQRTVW 684 >gi|320353995|ref|YP_004195334.1| AMP-dependent synthetase and ligase [Desulfobulbus propionicus DSM 2032] gi|320122497|gb|ADW18043.1| AMP-dependent synthetase and ligase [Desulfobulbus propionicus DSM 2032] Length=964 Score = 200 bits (509), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 167/562 (30%), Positives = 262/562 (47%), Gaps = 73/562 (12%) Query 28 EDSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPI 87 E+ +S++ L+ +A A L LD++ G V + T L++ F G++L GAVPVP+ Sbjct 169 EEPVTVSHRTLLDQATAIAAGLEALDVQPGASVALMLPTGLDYFFSFFGVLLAGAVPVPL 228 Query 88 -PPREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGD-E 145 PP + + LR HR ++ +CQ +AEA Sbjct 229 YPPLRPSQFEDH--------LRRHRHIL--------------NNCQALLLITVAEARPLA 266 Query 146 QFGRA---------TAQQLADTATADWPL-CTLDDDAYVQYTSGSTAAPRGVVITYRNLL 195 +F +A T ++L TA P+ + +D A++QYTSGST P+GV++++ NLL Sbjct 267 RFLKAQVDSLRRIVTVEELQKAGTAFTPVSASPEDTAFLQYTSGSTGIPKGVILSHANLL 326 Query 196 SNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFL 255 +N+RAM D+ SWLPL+HDMGL+G+ +L++ V +P FL P +L Sbjct 327 TNIRAMGRAIDANPRDIFVSWLPLYHDMGLIGAWLGSLYHGCQLVAMSPLAFLVHPERWL 386 Query 256 RLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAA 315 + T + PNF E +N ++G+DL R +EPV AE + RF Sbjct 387 WAIHRHRGTLSAAPNFGYELCLNKIE--PPQLDGLDLSSWRLAFNGAEPVSAETIARFTD 444 Query 316 TFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETH--------------AAAE--- 358 FA G P A+ YGLAE+TV ++ P G R +A E Sbjct 445 RFAPHGFRPEAMAPVYGLAESTVGLAF--PPLGRRPLIDRVQRQPLLERGLALSAGEDDP 502 Query 359 ----VVTGGRVLPGYEVRIDAA-----PGARAGTIKLRGDSVAAKAYVGGKKLDALDEEG 409 +V GRVL G+++R+ A P + G ++ G S + Y ++ L Sbjct 503 HPLRIVACGRVLSGHQLRVVDANDHELPERQVGRLQFYGPSATSGYYRSPQQTKTLFHGQ 562 Query 410 FCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTK-VACFGV-- 466 + DT DLG+L ++ + R ++ I G N PY++E I GE E R VA FG Sbjct 563 WLDTGDLGYLAGQDLYLTSRVKDLIIRGGRNISPYELEEAI-GEIEGVRKGCVAVFGNAD 621 Query 467 ----NERVVVVLES-PLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKL 521 E++VV+ ES D + +R+ + V G+ DE++ + T+SGK+ Sbjct 622 PTSGTEKLVVLAESRSRDPGMLANLRERIINRSVDILGMPPDEVVLAPPHTVLKTSSGKI 681 Query 522 KRRAVAQAYRDGTLPRLATHAW 543 +R A + Y G + + W Sbjct 682 RREASRELYAQGRIGQPPRAVW 703 Lambda K H 0.322 0.135 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1255828141926 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40