BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0052

Length=187
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|253796967|ref|YP_003029968.1|  hypothetical protein TBMG_00051...   379    1e-103
gi|345461991|ref|NP_214566.2|  hypothetical protein Rv0052 [Mycob...   379    1e-103
gi|15839429|ref|NP_334466.1|  hypothetical protein MT0058 [Mycoba...   379    1e-103
gi|31791229|ref|NP_853722.1|  hypothetical protein Mb0053 [Mycoba...   377    4e-103
gi|339293128|gb|AEJ45239.1|  hypothetical protein CCDC5079_0049 [...   335    1e-90 
gi|289764166|ref|ZP_06523544.1|  conserved hypothetical protein [...   323    6e-87 
gi|254818594|ref|ZP_05223595.1|  DJ-1/PfpI family protein [Mycoba...   253    8e-66 
gi|342860218|ref|ZP_08716870.1|  DJ-1/PfpI family protein [Mycoba...   249    1e-64 
gi|183980106|ref|YP_001848397.1|  transcriptional regulatory prot...   249    1e-64 
gi|118615982|ref|YP_904314.1|  transcriptional regulatory protein...   249    2e-64 
gi|336459418|gb|EGO38360.1|  transcriptional regulator containing...   244    4e-63 
gi|41406164|ref|NP_959000.1|  hypothetical protein MAP0066 [Mycob...   244    4e-63 
gi|240168782|ref|ZP_04747441.1|  transcriptional regulatory prote...   243    9e-63 
gi|118465152|ref|YP_879373.1|  DJ-1/PfpI family protein [Mycobact...   243    9e-63 
gi|296167067|ref|ZP_06849479.1|  DJ-1/PfpI family protein [Mycoba...   238    2e-61 
gi|331694272|ref|YP_004330511.1|  ThiJ/PfpI domain-containing pro...   221    4e-56 
gi|333991294|ref|YP_004523908.1|  transcriptional regulator [Myco...   211    4e-53 
gi|168032228|ref|XP_001768621.1|  predicted protein [Physcomitrel...   190    7e-47 
gi|254548984|ref|ZP_05139431.1|  hypothetical protein Mtube_00721...   184    5e-45 
gi|302785824|ref|XP_002974683.1|  hypothetical protein SELMODRAFT...   173    8e-42 
gi|302759951|ref|XP_002963398.1|  hypothetical protein SELMODRAFT...   173    1e-41 
gi|302784298|ref|XP_002973921.1|  hypothetical protein SELMODRAFT...   172    3e-41 
gi|39933002|gb|AAR32679.1|  4-methyl-5(B-hydroxyethyl)-thiazole m...   172    3e-41 
gi|302548312|ref|ZP_07300654.1|  putative 4-methyl-5(B-hydroxyeth...   166    1e-39 
gi|302771445|ref|XP_002969141.1|  hypothetical protein SELMODRAFT...   166    1e-39 
gi|254391851|ref|ZP_05007045.1|  conserved hypothetical protein [...   158    3e-37 
gi|294816230|ref|ZP_06774873.1|  4-methyl-5 B-hydroxyethyl -thiaz...   158    3e-37 
gi|226312574|ref|YP_002772468.1|  hypothetical protein BBR47_2987...   158    3e-37 
gi|290963231|ref|YP_003494413.1|  hypothetical protein SCAB_89551...   158    5e-37 
gi|302769864|ref|XP_002968351.1|  hypothetical protein SELMODRAFT...   157    5e-37 
gi|339007797|ref|ZP_08640371.1|  putative 4-methyl-5(B-hydroxyeth...   157    9e-37 
gi|302765010|ref|XP_002965926.1|  hypothetical protein SELMODRAFT...   155    2e-36 
gi|145225840|ref|YP_001136518.1|  ThiJ/PfpI domain-containing pro...   155    3e-36 
gi|149924861|ref|ZP_01913198.1|  ThiJ/PfpI [Plesiocystis pacifica...   155    4e-36 
gi|302765006|ref|XP_002965924.1|  hypothetical protein SELMODRAFT...   154    8e-36 
gi|120401988|ref|YP_951817.1|  ThiJ/PfpI domain-containing protei...   153    1e-35 
gi|312197660|ref|YP_004017721.1|  ThiJ/PfpI domain-containing pro...   151    4e-35 
gi|328886478|emb|CCA59717.1|  ThiJ or PfpI family protein [Strept...   150    6e-35 
gi|262204278|ref|YP_003275486.1|  thiJ/PfpI domain-containing pro...   150    1e-34 
gi|343924457|ref|ZP_08764006.1|  putative ThiJ/PfpI family protei...   146    2e-33 
gi|333919956|ref|YP_004493537.1|  ThiJ/PfpI domain-containing pro...   146    2e-33 
gi|118471850|ref|YP_885501.1|  isonitrile hydratase [Mycobacteriu...   145    2e-33 
gi|317130619|ref|YP_004096901.1|  ThiJ/PfpI domain-containing pro...   143    1e-32 
gi|167461180|ref|ZP_02326269.1|  4-methyl-5(B-hydroxyethyl)-thiaz...   143    1e-32 
gi|126650641|ref|ZP_01722864.1|  putative 4-methyl-5(B-hydroxyeth...   142    2e-32 
gi|302541561|ref|ZP_07293903.1|  putative 4-methyl-5(B-hydroxyeth...   142    3e-32 
gi|169628040|ref|YP_001701689.1|  hypothetical protein MAB_0943 [...   142    3e-32 
gi|159898619|ref|YP_001544866.1|  ThiJ/PfpI domain-containing pro...   141    4e-32 
gi|29828208|ref|NP_822842.1|  4-methyl-5(B-hydroxyethyl)-thiazole...   141    5e-32 
gi|167461306|ref|ZP_02326395.1|  4-methyl-5(B-hydroxyethyl)-thiaz...   141    5e-32 


>gi|253796967|ref|YP_003029968.1| hypothetical protein TBMG_00051 [Mycobacterium tuberculosis KZN 
1435]
 gi|308232626|ref|ZP_07416680.2| hypothetical protein TMAG_00722 [Mycobacterium tuberculosis SUMu001]
 gi|308369291|ref|ZP_07417211.2| hypothetical protein TMBG_02516 [Mycobacterium tuberculosis SUMu002]
 24 more sequence titles
 Length=212

 Score =  379 bits (973),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 187/187 (100%), Positives = 187/187 (100%), Gaps = 0/187 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW
Sbjct  26   VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE
Sbjct  86   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL
Sbjct  146  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  205

Query  181  EFYQHRL  187
            EFYQHRL
Sbjct  206  EFYQHRL  212


>gi|345461991|ref|NP_214566.2| hypothetical protein Rv0052 [Mycobacterium tuberculosis H37Rv]
Length=191

 Score =  379 bits (973),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 187/187 (100%), Positives = 187/187 (100%), Gaps = 0/187 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW
Sbjct  5    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  64

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE
Sbjct  65   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  124

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL
Sbjct  125  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  184

Query  181  EFYQHRL  187
            EFYQHRL
Sbjct  185  EFYQHRL  191


>gi|15839429|ref|NP_334466.1| hypothetical protein MT0058 [Mycobacterium tuberculosis CDC1551]
 gi|254233451|ref|ZP_04926777.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
 gi|254366510|ref|ZP_04982554.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|13879101|gb|AAK44280.1| 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme, putative [Mycobacterium tuberculosis CDC1551]
 gi|124603244|gb|EAY61519.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
 gi|134152022|gb|EBA44067.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|323717391|gb|EGB26596.1| hypothetical protein TMMG_00471 [Mycobacterium tuberculosis CDC1551A]
Length=212

 Score =  379 bits (973),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 187/187 (100%), Positives = 187/187 (100%), Gaps = 0/187 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW
Sbjct  26   VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE
Sbjct  86   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL
Sbjct  146  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  205

Query  181  EFYQHRL  187
            EFYQHRL
Sbjct  206  EFYQHRL  212


>gi|31791229|ref|NP_853722.1| hypothetical protein Mb0053 [Mycobacterium bovis AF2122/97]
 gi|121635962|ref|YP_976185.1| hypothetical protein BCG_0083 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|148659812|ref|YP_001281335.1| hypothetical protein MRA_0055 [Mycobacterium tuberculosis H37Ra]
 41 more sequence titles
 Length=187

 Score =  377 bits (968),  Expect = 4e-103, Method: Compositional matrix adjust.
 Identities = 186/187 (99%), Positives = 187/187 (100%), Gaps = 0/187 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW
Sbjct  1    MPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE
Sbjct  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL
Sbjct  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180

Query  181  EFYQHRL  187
            EFYQHRL
Sbjct  181  EFYQHRL  187


>gi|339293128|gb|AEJ45239.1| hypothetical protein CCDC5079_0049 [Mycobacterium tuberculosis 
CCDC5079]
Length=166

 Score =  335 bits (860),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 166/166 (100%), Positives = 166/166 (100%), Gaps = 0/166 (0%)

Query  22   MLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVL  81
            MLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVL
Sbjct  1    MLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVL  60

Query  82   AAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVEL  141
            AAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVEL
Sbjct  61   AAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVEL  120

Query  142  LVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL  187
            LVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL
Sbjct  121  LVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL  166


>gi|289764166|ref|ZP_06523544.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|289711672|gb|EFD75688.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
Length=165

 Score =  323 bits (829),  Expect = 6e-87, Method: Compositional matrix adjust.
 Identities = 162/166 (98%), Positives = 163/166 (99%), Gaps = 1/166 (0%)

Query  22   MLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVL  81
            MLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHT  + SVCTGGLVL
Sbjct  1    MLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREAHRHTY-SHSVCTGGLVL  59

Query  82   AAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVEL  141
            AAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVEL
Sbjct  60   AAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVEL  119

Query  142  LVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL  187
            LVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL
Sbjct  120  LVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL  165


>gi|254818594|ref|ZP_05223595.1| DJ-1/PfpI family protein [Mycobacterium intracellulare ATCC 13950]
Length=213

 Score =  253 bits (647),  Expect = 8e-66, Method: Compositional matrix adjust.
 Identities = 131/186 (71%), Positives = 155/186 (84%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS +VVFVGHRRGEVR+DN MLG+ CDA FDE++ P+VV+FPGGIGTR LIHD+ + DW
Sbjct  27   IPSIEVVFVGHRRGEVRTDNGMLGVTCDATFDEVSAPEVVVFPGGIGTRQLIHDEAIRDW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R  H +T  TTSVCTG L+LAAAGLL GLTATTHW   DL N+LGARYVP+RVVEHLP+
Sbjct  87   LRAVHPNTRFTTSVCTGSLLLAAAGLLEGLTATTHWGAADLLNNLGARYVPERVVEHLPQ  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV R+AA+A+QL+IEYDPQPP D+G+LAKA PAT     
Sbjct  147  RIITAAGVSSGIDMALRLVELLVDRQAAQAAQLLIEYDPQPPFDSGALAKADPATLARVK  206

Query  181  EFYQHR  186
            E+   R
Sbjct  207  EYMAAR  212


>gi|342860218|ref|ZP_08716870.1| DJ-1/PfpI family protein [Mycobacterium colombiense CECT 3035]
 gi|342132596|gb|EGT85825.1| DJ-1/PfpI family protein [Mycobacterium colombiense CECT 3035]
Length=213

 Score =  249 bits (637),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 130/186 (70%), Positives = 155/186 (84%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS DVVFVGHRRGEVR++N MLG+ CDA FDE+  PDVV+FPGGIGTR L+HD+ +  W
Sbjct  27   IPSMDVVFVGHRRGEVRTENGMLGVSCDATFDEVDAPDVVVFPGGIGTRQLVHDEAIRAW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H +T  TTSVCTG L+LAAAGLL+GLTATTHWR  DL N LGARYVP+RVVEHLP+
Sbjct  87   LQAVHPNTTFTTSVCTGALLLAAAGLLDGLTATTHWRAADLLNGLGARYVPERVVEHLPQ  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV REAA+A+QL+IEYDPQPP D+G+LAK+  AT   A 
Sbjct  147  RIITAAGVSSGIDMALRLVELLVDREAAQAAQLLIEYDPQPPFDSGALAKSDAATVARAH  206

Query  181  EFYQHR  186
            E+ + R
Sbjct  207  EYLEAR  212


>gi|183980106|ref|YP_001848397.1| transcriptional regulatory protein [Mycobacterium marinum M]
 gi|183173432|gb|ACC38542.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=212

 Score =  249 bits (636),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 130/186 (70%), Positives = 153/186 (83%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS DVVF+GH+RGEVR++N MLG+ CDA F E+  PDVV+FPGGIGTR L+ D+T+  W
Sbjct  26   IPSIDVVFIGHQRGEVRTENGMLGVTCDATFAEVDAPDVVVFPGGIGTRGLLEDETIRGW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H HT  TTSVCTG L+LAAAGLL+GLTATTHWR  +L N LGARYVPQRVVEHLP+
Sbjct  86   LQAVHPHTRFTTSVCTGALLLAAAGLLDGLTATTHWRAAELLNGLGARYVPQRVVEHLPQ  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDMGLRLVELLV REAA+A+QL+IEYDP+PP DAGSLAKA       A+
Sbjct  146  RIITAAGVSSGIDMGLRLVELLVDREAAQAAQLLIEYDPEPPFDAGSLAKADEGVRARAI  205

Query  181  EFYQHR  186
            EF   R
Sbjct  206  EFLDSR  211


>gi|118615982|ref|YP_904314.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
 gi|118568092|gb|ABL02843.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
Length=212

 Score =  249 bits (635),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 130/186 (70%), Positives = 152/186 (82%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS DVVF+GH+RGEVR++N MLG+ CDA FDE+  PDVV FPGGIGTR L+ D+T+  W
Sbjct  26   IPSIDVVFIGHQRGEVRTENGMLGVTCDATFDEVDAPDVVAFPGGIGTRGLLEDETIRGW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H HT  TTSVCTG L+LAAAGLL+GLTATTHWR  +L N LGARYVPQRVVEHLP+
Sbjct  86   LQAVHPHTRFTTSVCTGALLLAAAGLLDGLTATTHWRAAELLNGLGARYVPQRVVEHLPQ  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDMGLRLVELLV REAA+ +QL+IEYDP+PP DAGSLAKA       A+
Sbjct  146  RIITAAGVSSGIDMGLRLVELLVDREAAQVTQLLIEYDPEPPFDAGSLAKADEGVRARAI  205

Query  181  EFYQHR  186
            EF   R
Sbjct  206  EFLDSR  211


>gi|336459418|gb|EGO38360.1| transcriptional regulator containing an amidase domain and AraC-type 
DNA-binding HTH [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=213

 Score =  244 bits (623),  Expect = 4e-63, Method: Compositional matrix adjust.
 Identities = 130/186 (70%), Positives = 150/186 (81%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS  VVFVG RRGEVR++N MLGL CDA FDE++ PDVV+FPGGIGTR LIHD+ V  W
Sbjct  27   IPSVQVVFVGQRRGEVRTENGMLGLACDATFDEVSAPDVVVFPGGIGTRQLIHDEAVRAW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H HT  TTSVCTG L+LAAAGLL+GLTATTHWR  DL N LGARYV QRVVEHLP+
Sbjct  87   LQAVHPHTRFTTSVCTGALLLAAAGLLDGLTATTHWRAADLLNGLGARYVEQRVVEHLPQ  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV R+AA+A+QL+IEYDPQPP D+G+  KA  AT   A 
Sbjct  147  RIITAAGVSSGIDMALRLVELLVDRQAAQAAQLLIEYDPQPPFDSGAFGKADAATVARAE  206

Query  181  EFYQHR  186
            E+   R
Sbjct  207  EYLTGR  212


>gi|41406164|ref|NP_959000.1| hypothetical protein MAP0066 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394512|gb|AAS02383.1| hypothetical protein MAP_0066 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=213

 Score =  244 bits (623),  Expect = 4e-63, Method: Compositional matrix adjust.
 Identities = 130/186 (70%), Positives = 150/186 (81%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS  VVFVG RRGEVR++N MLGL CDA FDE++ PDVV+FPGGIGTR LIHD+ V  W
Sbjct  27   IPSVQVVFVGQRRGEVRTENGMLGLACDATFDEVSAPDVVVFPGGIGTRQLIHDEAVRAW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H HT  TTSVCTG L+LAAAGLL+GLTATTHWR  DL N LGARYV QRVVEHLP+
Sbjct  87   LQAVHPHTRFTTSVCTGALLLAAAGLLDGLTATTHWRAADLLNGLGARYVEQRVVEHLPQ  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV R+AA+A+QL+IEYDPQPP D+G+  KA  AT   A 
Sbjct  147  RIITAAGVSSGIDMALRLVELLVDRQAAQAAQLLIEYDPQPPFDSGAFGKADAATVARAE  206

Query  181  EFYQHR  186
            E+   R
Sbjct  207  EYLTGR  212


>gi|240168782|ref|ZP_04747441.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC 
12478]
Length=212

 Score =  243 bits (620),  Expect = 9e-63, Method: Compositional matrix adjust.
 Identities = 128/186 (69%), Positives = 152/186 (82%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS DVVFVGHRRGE+R++N MLGL+CDA F+E+  PDVV+FPGGIGTR L+ D+ +  W
Sbjct  26   IPSIDVVFVGHRRGELRTENGMLGLVCDATFEEVGTPDVVVFPGGIGTRVLLDDEIICGW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H HT  TTSVCTG L+LAAAGLL+GLTATTHWR  +L N LGARYVP RVVEHLP+
Sbjct  86   LQSVHPHTRFTTSVCTGALLLAAAGLLDGLTATTHWRAAELLNELGARYVPDRVVEHLPQ  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV REAA+A+QL+IEYDP+PP  +GSLA A  AT   A 
Sbjct  146  RIITAAGVSSGIDMALRLVELLVDREAAQAAQLLIEYDPRPPFASGSLANADEATRIRAA  205

Query  181  EFYQHR  186
            EF + R
Sbjct  206  EFLRSR  211


>gi|118465152|ref|YP_879373.1| DJ-1/PfpI family protein [Mycobacterium avium 104]
 gi|254773119|ref|ZP_05214635.1| DJ-1/PfpI family protein [Mycobacterium avium subsp. avium ATCC 
25291]
 gi|118166439|gb|ABK67336.1| DJ-1/PfpI family protein [Mycobacterium avium 104]
Length=213

 Score =  243 bits (620),  Expect = 9e-63, Method: Compositional matrix adjust.
 Identities = 129/186 (70%), Positives = 150/186 (81%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +PS  VVF+G RRGEVR++N MLGL CDA FDE++ PDVV+FPGGIGTR LIHD+ V  W
Sbjct  27   IPSVQVVFIGQRRGEVRTENGMLGLACDATFDEVSAPDVVVFPGGIGTRQLIHDEAVRAW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H HT  TTSVCTG L+LAAAGLL+GLTATTHWR  DL   LGARYV QRVVEHLP+
Sbjct  87   LQAVHPHTRFTTSVCTGALLLAAAGLLDGLTATTHWRAADLLKGLGARYVEQRVVEHLPQ  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV R+AA+A+QL+IEYDPQPP D+G+L KA  AT   A 
Sbjct  147  RIITAAGVSSGIDMALRLVELLVDRQAAQAAQLLIEYDPQPPFDSGALGKADAATVARAE  206

Query  181  EFYQHR  186
            E+   R
Sbjct  207  EYLTGR  212


>gi|296167067|ref|ZP_06849479.1| DJ-1/PfpI family protein [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295897624|gb|EFG77218.1| DJ-1/PfpI family protein [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=213

 Score =  238 bits (608),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 131/186 (71%), Positives = 150/186 (81%), Gaps = 0/186 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VPS +VVF+GHRRGEVR++N MLGL CDA FDE+T PDVV+FPGGIGTR LIHD T+  W
Sbjct  27   VPSVEVVFIGHRRGEVRTENGMLGLCCDARFDEVTSPDVVLFPGGIGTRRLIHDDTIRAW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            ++  H  T  TTSVCTG L+LA AGLL+GLTATTHWR   L N LGARYVP RVVEHL +
Sbjct  87   LQAVHPTTTFTTSVCTGALLLAGAGLLDGLTATTHWRASGLLNELGARYVPDRVVEHLSQ  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R+ITAAGVSSGIDM LRLVELLV R+AA+A+QL+IEYDPQPP D+GSLAKA  AT   A 
Sbjct  147  RIITAAGVSSGIDMALRLVELLVDRQAAQAAQLLIEYDPQPPFDSGSLAKADRATVDRAT  206

Query  181  EFYQHR  186
            E+   R
Sbjct  207  EYLDAR  212


>gi|331694272|ref|YP_004330511.1| ThiJ/PfpI domain-containing protein [Pseudonocardia dioxanivorans 
CB1190]
 gi|326948961|gb|AEA22658.1| ThiJ/PfpI domain-containing protein [Pseudonocardia dioxanivorans 
CB1190]
Length=212

 Score =  221 bits (563),  Expect = 4e-56, Method: Compositional matrix adjust.
 Identities = 110/172 (64%), Positives = 130/172 (76%), Gaps = 0/172 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VP  DVVFVG RRGEVR++N MLGL  DA F ++  PDVV+ PGGIG+R L+    ++DW
Sbjct  26   VPDIDVVFVGERRGEVRTENGMLGLSVDATFADIPSPDVVVVPGGIGSRALLAGGPLVDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VR AH  T  TTSVC+G LVL AAGLL+GLTATTHW   D+    GA  V QRVVEHLPE
Sbjct  86   VRAAHPGTRFTTSVCSGALVLGAAGLLDGLTATTHWGAFDVLARFGATPVTQRVVEHLPE  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKAS  172
            R++TAAGVS+GIDM LRL+ELLV   AA+A+Q+ IEYDPQPP DAG  +K S
Sbjct  146  RIVTAAGVSAGIDMALRLLELLVDDVAAQAAQVFIEYDPQPPFDAGHPSKVS  197


>gi|333991294|ref|YP_004523908.1| transcriptional regulator [Mycobacterium sp. JDM601]
 gi|333487262|gb|AEF36654.1| transcriptional regulatory protein [Mycobacterium sp. JDM601]
Length=209

 Score =  211 bits (537),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 123/182 (68%), Positives = 142/182 (79%), Gaps = 0/182 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VP  + VFVGHR GEVRSDN MLG+ CDA FDE+ RPDVV+ PGG+GTR L+ D  +LDW
Sbjct  26   VPEVETVFVGHRHGEVRSDNGMLGITCDARFDEVIRPDVVVVPGGVGTRVLLDDAELLDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+ H HT  TTSVCTG L+LAAAGLL+GLTATTHW   +L   LGARYV QRVVEHLP+
Sbjct  86   LRQIHPHTRFTTSVCTGSLLLAAAGLLDGLTATTHWGAIELLEHLGARYVEQRVVEHLPQ  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            R++T+AGVSSGIDM LRLVELLV  E A+A+QLMIEYDPQPP D GSL KA  A    A 
Sbjct  146  RILTSAGVSSGIDMALRLVELLVDTETAQAAQLMIEYDPQPPFDCGSLPKADEAVRNRAA  205

Query  181  EF  182
            + 
Sbjct  206  QL  207


>gi|168032228|ref|XP_001768621.1| predicted protein [Physcomitrella patens subsp. patens]
 gi|162680120|gb|EDQ66559.1| predicted protein [Physcomitrella patens subsp. patens]
Length=275

 Score =  190 bits (483),  Expect = 7e-47, Method: Compositional matrix adjust.
 Identities = 92/186 (50%), Positives = 123/186 (67%), Gaps = 2/186 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P+ +VV V H +G +R++ +++G    A FDE+  PD+VI PGG G   LI D+ +LDW
Sbjct  85   LPNVNVVLVSHSKGIIRAEKSLIGFEATATFDEVQEPDIVIVPGGYGVNALIRDKPILDW  144

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+ H  TL TTSVCTG L+LAAAG+LNGL AT HWRV    +  GA+    R+VE    
Sbjct  145  IRKTHEKTLYTTSVCTGSLLLAAAGILNGLEATCHWRVLPELSKFGAKPTSSRIVES--G  202

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            ++ITAAGVS+GIDMGL+LV LL +    +  QL+IEYDPQPP D GS A A P    +A 
Sbjct  203  KIITAAGVSAGIDMGLKLVALLSNDTTCKLIQLVIEYDPQPPFDCGSPAAAGPELVSMAR  262

Query  181  EFYQHR  186
             + +  
Sbjct  263  AYAEKN  268


>gi|254548984|ref|ZP_05139431.1| hypothetical protein Mtube_00721 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
Length=115

 Score =  184 bits (467),  Expect = 5e-45, Method: Compositional matrix adjust.
 Identities = 90/90 (100%), Positives = 90/90 (100%), Gaps = 0/90 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW
Sbjct  26   VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGL  90
            VREAHRHTLLTTSVCTGGLVLAAAGLLNGL
Sbjct  86   VREAHRHTLLTTSVCTGGLVLAAAGLLNGL  115


>gi|302785824|ref|XP_002974683.1| hypothetical protein SELMODRAFT_442624 [Selaginella moellendorffii]
 gi|300157578|gb|EFJ24203.1| hypothetical protein SELMODRAFT_442624 [Selaginella moellendorffii]
Length=802

 Score =  173 bits (439),  Expect = 8e-42, Method: Compositional matrix adjust.
 Identities = 93/187 (50%), Positives = 123/187 (66%), Gaps = 2/187 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P+ +V+FV H+ G   +   ML L   A+FD++TRP +++ PGG+GTR L+ D+ +LDW
Sbjct  591  LPNVEVLFVSHQPGLYAAGMGMLTLQATASFDQVTRPQILVVPGGMGTRRLLQDRVILDW  650

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+ H HTL T SVCTG L+L AAGLL G+ ATTHW   +L    GA+ V  R+V     
Sbjct  651  IRKVHEHTLYTASVCTGSLLLGAAGLLKGIEATTHWNSHELLAEFGAKPVSSRIVRQ--G  708

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            ++ITAAGVS+GIDM L+L  LL     A+  QL IEYDPQPP D+GS+AKA P     A 
Sbjct  709  KIITAAGVSAGIDMALQLAALLTDEATAKTLQLFIEYDPQPPFDSGSVAKAGPEVVSRAK  768

Query  181  EFYQHRL  187
            E    RL
Sbjct  769  ELSSKRL  775


>gi|302759951|ref|XP_002963398.1| hypothetical protein SELMODRAFT_438544 [Selaginella moellendorffii]
 gi|300168666|gb|EFJ35269.1| hypothetical protein SELMODRAFT_438544 [Selaginella moellendorffii]
Length=809

 Score =  173 bits (439),  Expect = 1e-41, Method: Compositional matrix adjust.
 Identities = 93/187 (50%), Positives = 123/187 (66%), Gaps = 2/187 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P+ +V+FV H+ G   +   ML L   A+FD++TRP +++ PGG+GTR L+ D+ +LDW
Sbjct  597  LPNVEVLFVSHQPGLYAAGMGMLTLQATASFDQVTRPQILVVPGGMGTRRLLQDRVILDW  656

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+ H HTL T SVCTG L+L AAGLL G+ ATTHW   +L    GA+ V  R+V     
Sbjct  657  IRKVHEHTLYTASVCTGSLLLGAAGLLKGIEATTHWNSHELLAEFGAKPVSSRIVRQ--G  714

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            ++ITAAGVS+GIDM L+L  LL     A+  QL IEYDPQPP D+GS+AKA P     A 
Sbjct  715  KIITAAGVSAGIDMALQLAALLTDEATAKTLQLFIEYDPQPPFDSGSVAKAGPEVVSRAK  774

Query  181  EFYQHRL  187
            E    RL
Sbjct  775  ELSSKRL  781


>gi|302784298|ref|XP_002973921.1| hypothetical protein SELMODRAFT_100248 [Selaginella moellendorffii]
 gi|300158253|gb|EFJ24876.1| hypothetical protein SELMODRAFT_100248 [Selaginella moellendorffii]
Length=219

 Score =  172 bits (435),  Expect = 3e-41, Method: Compositional matrix adjust.
 Identities = 90/185 (49%), Positives = 117/185 (64%), Gaps = 7/185 (3%)

Query  1    VPSFDVVFVGHRRGEVRSDNAM---LGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTV  57
            VP   VVFV  + G + +  A    LGL   A++ ++  PDV++ PGG  T+  +H + +
Sbjct  33   VPGVSVVFVSDKPGLILAGEAQQSHLGLRATASYKDVPHPDVIVVPGGPPTKIPLHHKPL  92

Query  58   LDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEH  117
            LDW+R+AH  TL TTSVCTG L+L +AGLL GL  TTHW         GA+   +R ++ 
Sbjct  93   LDWIRKAHETTLFTTSVCTGALILGSAGLLTGLECTTHWSSYKKLEEFGAKASAKRYIQQ  152

Query  118  LPERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHR  177
               ++ITAAGVSSGIDM L L  LL  +  AE  QL++EYDPQPP D+GSLAKASP    
Sbjct  153  --GKIITAAGVSSGIDMALYLAALLKDKVIAEGVQLLVEYDPQPPFDSGSLAKASPEV--  208

Query  178  LALEF  182
            LAL F
Sbjct  209  LALPF  213


>gi|39933002|gb|AAR32679.1| 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces hygroscopicus]
Length=270

 Score =  172 bits (435),  Expect = 3e-41, Method: Compositional matrix adjust.
 Identities = 93/185 (51%), Positives = 108/185 (59%), Gaps = 2/185 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P   V FVG  +G V+     L     A + E+ R DV++ PGG     ++ D   L W
Sbjct  83   MPGASVRFVGAEKGPVKDALGSLPTYVPATYSEVERCDVLLIPGGRSVEAMVADADFLAW  142

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VR  H  T  TTSVCTG LVL AAGLL GLTATTHW   +   S GA Y PQR V     
Sbjct  143  VRRIHARTRFTTSVCTGSLVLGAAGLLKGLTATTHWSGAEALESYGAAYTPQRTVRQ--G  200

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            +VIT+AGVSSGIDM L L  LL     A+A QL IEYDPQPP D+GSLAKAS A  R   
Sbjct  201  KVITSAGVSSGIDMALTLAALLTDEVTAQAIQLWIEYDPQPPFDSGSLAKASDAVKRRVF  260

Query  181  EFYQH  185
            E  + 
Sbjct  261  ELVKE  265


>gi|302548312|ref|ZP_07300654.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces hygroscopicus ATCC 53653]
 gi|302465930|gb|EFL29023.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces himastatinicus ATCC 53653]
Length=260

 Score =  166 bits (421),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 84/173 (49%), Positives = 107/173 (62%), Gaps = 2/173 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            VP   V  V  + G +R+D   L L+ + + D + R DV++ PGG GT+  + +  VLDW
Sbjct  75   VPRVTVTMVAEKAGRIRTDTGELTLVAERSLDSVDRADVLVVPGGSGTKATMENTVVLDW  134

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R  HR ++ TTSVCTG L+L AAGLL GL ATT W  +     LGA Y P R VE    
Sbjct  135  IRHIHRRSVWTTSVCTGSLILGAAGLLRGLPATTFWAGRSYLADLGAEYTPGRFVEA--G  192

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASP  173
            ++ITAAGVS+GIDMGL L   L   + A+A QL +EYDP PP D GS  KA P
Sbjct  193  KIITAAGVSAGIDMGLHLAARLSDEKVAQAMQLAVEYDPDPPFDTGSPEKAGP  245


>gi|302771445|ref|XP_002969141.1| hypothetical protein SELMODRAFT_91146 [Selaginella moellendorffii]
 gi|300163646|gb|EFJ30257.1| hypothetical protein SELMODRAFT_91146 [Selaginella moellendorffii]
Length=219

 Score =  166 bits (420),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 87/185 (48%), Positives = 115/185 (63%), Gaps = 7/185 (3%)

Query  1    VPSFDVVFVGHRRGEV---RSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTV  57
            VP   VVFV  + G +    + ++ LGL   A++ ++  PDV++ PGG  T+  +  + +
Sbjct  33   VPGVSVVFVSDKPGLILAGEAQDSHLGLRATASYKDVPHPDVIVVPGGPPTKIPLQHKPL  92

Query  58   LDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEH  117
            LDW+R+AH  TL TTSVCTG L+L +AGLL GL  TTHW         GA+   +R ++ 
Sbjct  93   LDWIRKAHETTLFTTSVCTGALILGSAGLLTGLECTTHWSSYKKLEEFGAKASAKRYIQQ  152

Query  118  LPERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHR  177
               ++ITAAGVSSGIDM L L  LL  +  AE  QL++EYDPQPP D GS AKASP    
Sbjct  153  --GKIITAAGVSSGIDMALYLAALLKDKVIAEGVQLLVEYDPQPPFDCGSRAKASPEV--  208

Query  178  LALEF  182
            LAL F
Sbjct  209  LALPF  213


>gi|254391851|ref|ZP_05007045.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 
27064]
 gi|197705532|gb|EDY51344.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 
27064]
Length=213

 Score =  158 bits (400),  Expect = 3e-37, Method: Compositional matrix adjust.
 Identities = 85/184 (47%), Positives = 110/184 (60%), Gaps = 4/184 (2%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGG--IGTRTLIHDQTVL  58
            VP   V  V  R G VR+D   LG+  + +  ++TRPDV++ PGG   GT   + D  +L
Sbjct  26   VPGVRVTTVATRAGLVRTDTGELGIAAEKSLPQVTRPDVLVVPGGGERGTTATMADARIL  85

Query  59   DWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHL  118
            +W+R  HRHT+ TTS+CTG L+L AAGLL GL ATT+W  +     +GA Y P R VE  
Sbjct  86   EWIRRVHRHTVWTTSICTGSLILGAAGLLRGLPATTYWASRPYVKEVGAVYTPGRFVET-  144

Query  119  PERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRL  178
              R+ITAAGVS+GIDMGL L   L   +   A +L +EYDP+PP   G    A   T  L
Sbjct  145  -GRIITAAGVSAGIDMGLHLAARLSDEQVGRAMELALEYDPEPPFRTGDPDTADERTRAL  203

Query  179  ALEF  182
            AL+ 
Sbjct  204  ALKL  207


>gi|294816230|ref|ZP_06774873.1| 4-methyl-5 B-hydroxyethyl -thiazole monophosphate biosynthesis 
enzyme [Streptomyces clavuligerus ATCC 27064]
 gi|326444560|ref|ZP_08219294.1| hypothetical protein SclaA2_26001 [Streptomyces clavuligerus 
ATCC 27064]
 gi|294328829|gb|EFG10472.1| 4-methyl-5 B-hydroxyethyl -thiazole monophosphate biosynthesis 
enzyme [Streptomyces clavuligerus ATCC 27064]
Length=257

 Score =  158 bits (400),  Expect = 3e-37, Method: Compositional matrix adjust.
 Identities = 85/184 (47%), Positives = 110/184 (60%), Gaps = 4/184 (2%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGG--IGTRTLIHDQTVL  58
            VP   V  V  R G VR+D   LG+  + +  ++TRPDV++ PGG   GT   + D  +L
Sbjct  70   VPGVRVTTVATRAGLVRTDTGELGIAAEKSLPQVTRPDVLVVPGGGERGTTATMADARIL  129

Query  59   DWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHL  118
            +W+R  HRHT+ TTS+CTG L+L AAGLL GL ATT+W  +     +GA Y P R VE  
Sbjct  130  EWIRRVHRHTVWTTSICTGSLILGAAGLLRGLPATTYWASRPYVKEVGAVYTPGRFVET-  188

Query  119  PERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRL  178
              R+ITAAGVS+GIDMGL L   L   +   A +L +EYDP+PP   G    A   T  L
Sbjct  189  -GRIITAAGVSAGIDMGLHLAARLSDEQVGRAMELALEYDPEPPFRTGDPDTADERTRAL  247

Query  179  ALEF  182
            AL+ 
Sbjct  248  ALKL  251


>gi|226312574|ref|YP_002772468.1| hypothetical protein BBR47_29870 [Brevibacillus brevis NBRC 100599]
 gi|226095522|dbj|BAH43964.1| conserved hypothetical protein [Brevibacillus brevis NBRC 100599]
Length=218

 Score =  158 bits (400),  Expect = 3e-37, Method: Compositional matrix adjust.
 Identities = 79/179 (45%), Positives = 116/179 (65%), Gaps = 2/179 (1%)

Query  5    DVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDWVREA  64
             + FV   +G ++ D+ M  L  +  + E+   DV+I PGGIG + L++D+  L+W+R+ 
Sbjct  30   KIKFVAKEKGLIQLDSKMGYLHAEYCYAEVPSMDVLIVPGGIGCKELMNDEETLNWIRQL  89

Query  65   HRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVIT  124
            H+ +  TTSVC+G +VL AAGLL G+ AT+HW V +   +LGA    +RVV H   +++T
Sbjct  90   HKTSKWTTSVCSGSMVLGAAGLLEGVPATSHWFVCESLRALGAIPQEERVVHH--GKIVT  147

Query  125  AAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFY  183
            AAGVSSGIDM L++V      E A+A+QL +EYDP+PP DAGS+  A PA  +   + Y
Sbjct  148  AAGVSSGIDMALQVVAWEFGVEIAQATQLTLEYDPKPPFDAGSVKTAPPAIVQYTKKVY  206


>gi|290963231|ref|YP_003494413.1| hypothetical protein SCAB_89551 [Streptomyces scabiei 87.22]
 gi|260652757|emb|CBG75890.1| conserved hypothetical protein [Streptomyces scabiei 87.22]
Length=253

 Score =  158 bits (399),  Expect = 5e-37, Method: Compositional matrix adjust.
 Identities = 85/185 (46%), Positives = 113/185 (62%), Gaps = 5/185 (2%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPG--GIGTRTLIHDQTVL  58
            +P   V  +  RRG VR+D A + +L + +  E+ R DV++ PG    GT   +++Q +L
Sbjct  65   LPDATVTMIAERRGPVRTDTADVAVLAERSLAEVDRLDVLLVPGAGNRGTVEAMNNQALL  124

Query  59   DWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNS-LGARYVPQRVVEH  117
             W+RE HRHT  TTSVCTG +VLAAAGLL G  ATT+W   D   S     Y+PQR V  
Sbjct  125  RWIREMHRHTRWTTSVCTGSIVLAAAGLLTGRRATTYWASADYLRSTFDVTYLPQRYVRS  184

Query  118  LPERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHR  177
               ++IT+AGVS+G+DM L L  L+   + A+A QL +EYDPQPP D+G  A ASP    
Sbjct  185  --GKIITSAGVSAGVDMSLYLASLIADDDTAKAIQLAVEYDPQPPFDSGDAAAASPRLKE  242

Query  178  LALEF  182
             AL  
Sbjct  243  RALRL  247


>gi|302769864|ref|XP_002968351.1| hypothetical protein SELMODRAFT_227780 [Selaginella moellendorffii]
 gi|300163995|gb|EFJ30605.1| hypothetical protein SELMODRAFT_227780 [Selaginella moellendorffii]
Length=215

 Score =  157 bits (398),  Expect = 5e-37, Method: Compositional matrix adjust.
 Identities = 78/183 (43%), Positives = 110/183 (61%), Gaps = 2/183 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P   V FV  + G V +D     +   + F++L  PD+++ PGG      +  + +LD+
Sbjct  30   LPGVSVTFVSDKPGLVVADEGTFKIEASSGFEDLPNPDILLVPGGPTKLLPLDHKPLLDY  89

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+AH  T  TTSVCTG L+L AAGLL G+ ATTHW         GA+   QR ++    
Sbjct  90   IRKAHECTTFTTSVCTGALILGAAGLLKGVKATTHWAAYPQLKEYGAKVTSQRYIKQ--G  147

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLAL  180
            +++TAAGVSSGIDM + L  ++ + + A+A QLMIEYDPQPP DAGS  KA     +LA 
Sbjct  148  KIVTAAGVSSGIDMAIYLASIITNEKIAKAVQLMIEYDPQPPYDAGSPCKAGEEIVKLAH  207

Query  181  EFY  183
            E +
Sbjct  208  ELW  210


>gi|339007797|ref|ZP_08640371.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Brevibacillus laterosporus LMG 15441]
 gi|338775000|gb|EGP34529.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Brevibacillus laterosporus LMG 15441]
Length=218

 Score =  157 bits (396),  Expect = 9e-37, Method: Compositional matrix adjust.
 Identities = 82/177 (47%), Positives = 115/177 (65%), Gaps = 5/177 (2%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGI--GTRTLIHDQTVL  58
            V   +V FV   +G ++ D+ M  L  D +F E+T  D+++ PG      ++L++D+  L
Sbjct  26   VKGNEVKFVAKDKGLIKLDSKMGYLHADFSFSEVTSADILVVPGCCPPNYKSLMNDEDTL  85

Query  59   DWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHL  118
            +W+R+ H+ T  TTSVCTG L+L+AAGLL GL AT+HW   DL  SLGA    +RVV   
Sbjct  86   NWIRKIHKTTKWTTSVCTGSLILSAAGLLKGLKATSHWSSLDLLQSLGAIPTDERVVRQ-  144

Query  119  PERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPAT  175
              +++TAAGVSSGIDM L+LV      E +++ QL++EYDP PP D GSL KA PA+
Sbjct  145  -GKIVTAAGVSSGIDMALQLVAWESGEEMSKSIQLLMEYDPMPPFDTGSLKKA-PAS  199


>gi|302765010|ref|XP_002965926.1| hypothetical protein SELMODRAFT_407075 [Selaginella moellendorffii]
 gi|300166740|gb|EFJ33346.1| hypothetical protein SELMODRAFT_407075 [Selaginella moellendorffii]
Length=673

 Score =  155 bits (393),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 77/177 (44%), Positives = 107/177 (61%), Gaps = 2/177 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P   V FV  + G V +D     +   A+F++L  PD+++ PGG      +  + +LD+
Sbjct  33   LPGVSVTFVSDKPGLVVADEGRFKIEASASFEDLPNPDILLVPGGTPKLLPLDHKPLLDY  92

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+AH  T  TTSVCTG L+L AAGLL G+ ATTHW         GA+   QR ++    
Sbjct  93   IRKAHECTTFTTSVCTGALILGAAGLLKGVKATTHWAAYPQLKEYGAKVTSQRYIKQ--G  150

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHR  177
            +++TAAGVSSGIDM + L  ++ + + A+A QLMIEYDPQPP DAGS  KA     R
Sbjct  151  KIVTAAGVSSGIDMAIYLASIITNEKIAKAVQLMIEYDPQPPYDAGSPCKAGEEITR  207


>gi|145225840|ref|YP_001136518.1| ThiJ/PfpI domain-containing protein [Mycobacterium gilvum PYR-GCK]
 gi|315442452|ref|YP_004075331.1| transcriptional regulator containing an amidase domain and an 
AraC-type DNA-binding HTH domain [Mycobacterium sp. Spyr1]
 gi|145218326|gb|ABP47730.1| ThiJ/PfpI domain protein [Mycobacterium gilvum PYR-GCK]
 gi|315260755|gb|ADT97496.1| transcriptional regulator containing an amidase domain and an 
AraC-type DNA-binding HTH domain [Mycobacterium sp. Spyr1]
Length=246

 Score =  155 bits (392),  Expect = 3e-36, Method: Compositional matrix adjust.
 Identities = 83/180 (47%), Positives = 115/180 (64%), Gaps = 2/180 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +V FV H  G + +D+ +L +    +FDE   PDV++ PGG  T     D+ VL W
Sbjct  26   LPDTEVRFVWHEPGPIAADSHVLLVGATHSFDETPSPDVILIPGGFATMEHARDEVVLAW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYV-PQRVVEHLP  119
            VR AH  +  TTSVC+G ++LAAAG+L+G  AT+HW    +  +LGA+ V  QR+VE   
Sbjct  86   VRRAHETSTWTTSVCSGSVILAAAGVLDGKRATSHWAALPVLKTLGAQPVGDQRIVE-AD  144

Query  120  ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLA  179
             + +TAAGVS+GID+GL L   +   E A+A QL +EYDPQPP D+G ++KAS  T  LA
Sbjct  145  AKTVTAAGVSAGIDLGLWLAGRIAGEEKAKAIQLSMEYDPQPPFDSGHMSKASAGTKALA  204


>gi|149924861|ref|ZP_01913198.1| ThiJ/PfpI [Plesiocystis pacifica SIR-1]
 gi|149814276|gb|EDM73881.1| ThiJ/PfpI [Plesiocystis pacifica SIR-1]
Length=246

 Score =  155 bits (391),  Expect = 4e-36, Method: Compositional matrix adjust.
 Identities = 85/174 (49%), Positives = 111/174 (64%), Gaps = 4/174 (2%)

Query  2    PSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIG-TRTLIHDQTVLDW  60
            P+ D+ FV    G + +D+ +L +    AF E  RPDV++ PG    T T++ D  VL W
Sbjct  31   PNIDLRFVWKEVGPIVTDSQVLVIGATHAFSETRRPDVILIPGSSADTATMMADADVLAW  90

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQ-RVVEHLP  119
            +R AH HT  TTSVC+G L+LAAAG+L+G  ATTHW V     + GA   P  RVV    
Sbjct  91   IRSAHPHTRFTTSVCSGALILAAAGVLDGHPATTHWMVTKSLLAFGAEPRPHDRVVRS--  148

Query  120  ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASP  173
             ++ITAAGVS+GIDM L L+  L   +AA+ SQL+IEYDPQPP D G ++KA P
Sbjct  149  GKIITAAGVSAGIDMALSLLAELEGEQAAKISQLLIEYDPQPPFDCGHVSKADP  202


>gi|302765006|ref|XP_002965924.1| hypothetical protein SELMODRAFT_439354 [Selaginella moellendorffii]
 gi|300166738|gb|EFJ33344.1| hypothetical protein SELMODRAFT_439354 [Selaginella moellendorffii]
Length=353

 Score =  154 bits (388),  Expect = 8e-36, Method: Compositional matrix adjust.
 Identities = 74/171 (44%), Positives = 106/171 (62%), Gaps = 2/171 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P   V FV  + G V +D     +   A+F++L  PD+++ PGG      +  + +LD+
Sbjct  33   LPGVSVTFVSDKPGLVVADEGRFKIEASASFEDLPNPDILLVPGGTPKLLPLDHKPLLDY  92

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+AH  T  TTSVCTG L+L AAGLL G+ ATTHW         GA+   QR ++    
Sbjct  93   IRKAHECTTFTTSVCTGALILGAAGLLKGVKATTHWAAYPQLKEYGAKVTSQRYIKQ--G  150

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKA  171
            +++TAAGVSSGIDM + L  ++ + + A+A QLMIEYDPQPP DAG+  +A
Sbjct  151  KIVTAAGVSSGIDMAIYLASIITNEKIAKAVQLMIEYDPQPPYDAGTWLRA  201


>gi|120401988|ref|YP_951817.1| ThiJ/PfpI domain-containing protein [Mycobacterium vanbaalenii 
PYR-1]
 gi|119954806|gb|ABM11811.1| ThiJ/PfpI domain protein [Mycobacterium vanbaalenii PYR-1]
Length=249

 Score =  153 bits (386),  Expect = 1e-35, Method: Compositional matrix adjust.
 Identities = 77/179 (44%), Positives = 112/179 (63%), Gaps = 0/179 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +V FV H  G + +D+ +L +    +FDE   PD+++ PGG  T     D+ VLDW
Sbjct  26   LPDVEVRFVWHEPGPIAADSHVLLVGATHSFDETPSPDLILIPGGFATMEHARDEKVLDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            VR AHR +  TTSVC+G ++LAA+G+L+G  AT+HW    +  + G + V    V    +
Sbjct  86   VRRAHRTSTWTTSVCSGSVILAASGVLDGKRATSHWAALPVLKTFGVQPVGDERVVVADD  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLA  179
            + +TAAGVS+GID+GL L   +     A+A QL +EYDPQPP D+G ++KAS +T  LA
Sbjct  146  KTVTAAGVSAGIDLGLWLAGQIAGESKAKAIQLSMEYDPQPPFDSGHMSKASASTKALA  204


>gi|312197660|ref|YP_004017721.1| ThiJ/PfpI domain-containing protein [Frankia sp. EuI1c]
 gi|311228996|gb|ADP81851.1| ThiJ/PfpI domain-containing protein [Frankia sp. EuI1c]
Length=214

 Score =  151 bits (382),  Expect = 4e-35, Method: Compositional matrix adjust.
 Identities = 85/173 (50%), Positives = 106/173 (62%), Gaps = 2/173 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +VVF GHR G VRS+   LGL+ DA   ++  PDVV+ PGG G   L+ D+ V  W
Sbjct  26   LPGAEVVFAGHRVGPVRSEGGRLGLIVDAELADVPAPDVVLVPGGPGQVALMDDEPVHAW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R     ++ TTSVCTG LVLAAAGLL G  AT++W   D    LGA    +RVV  +  
Sbjct  86   LRAVDATSVWTTSVCTGSLVLAAAGLLTGRRATSYWLALDQLAELGAVPTAERVV--VDG  143

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASP  173
            + +TAAGVS+GIDM L L   L     A+A QL +EYDP PP DAGS   A P
Sbjct  144  KYMTAAGVSAGIDMALTLAARLAGDSVAQALQLGVEYDPHPPFDAGSPRTAPP  196


>gi|328886478|emb|CCA59717.1| ThiJ or PfpI family protein [Streptomyces venezuelae ATCC 10712]
Length=214

 Score =  150 bits (380),  Expect = 6e-35, Method: Compositional matrix adjust.
 Identities = 80/171 (47%), Positives = 104/171 (61%), Gaps = 2/171 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  + VFV    G VR+D   L L+ D A  E+ RPD+V+ PGG  +R  + D  +  W
Sbjct  26   LPGAETVFVAKEAGPVRNDQGSLALVADKALAEVPRPDIVLVPGGPDSRAAMDDPEIQAW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R A   +  TTSVCTG L+LAAAG+L+G  ATTHW   +   +LG     +RVV     
Sbjct  86   LRTADETSTWTTSVCTGSLILAAAGVLDGRRATTHWLAHEELRALGVEPTGERVV--FDG  143

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKA  171
            + +TAAGVSSGIDM L L+  +   E A+  QL+ EYDPQPP DAGS  KA
Sbjct  144  KYVTAAGVSSGIDMALHLLGRIGGDETAQTIQLLTEYDPQPPYDAGSPDKA  194


>gi|262204278|ref|YP_003275486.1| thiJ/PfpI domain-containing protein [Gordonia bronchialis DSM 
43247]
 gi|262087625|gb|ACY23593.1| ThiJ/PfpI domain protein [Gordonia bronchialis DSM 43247]
Length=243

 Score =  150 bits (378),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 83/175 (48%), Positives = 108/175 (62%), Gaps = 1/175 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +V FV H  G + +D+ +L +     FDE  RPDVV+ PGG G      D+ VL W
Sbjct  27   LPDAEVRFVWHEPGPIAADSGVLLVGATHTFDETPRPDVVLIPGGPGCAEAARDERVLTW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R+AH     TTSVCTG +VLAAAGLL+G  AT+HW      +  GA+ V    V H  +
Sbjct  87   LRQAHPTATWTTSVCTGSIVLAAAGLLDGKRATSHWSAVAALSMYGAQAVTDERVVHAGD  146

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPAT  175
             V+TAAGVS+GID+ L+L   +   E A+A QL IEYDPQPP D+G  A AS +T
Sbjct  147  -VVTAAGVSAGIDLALQLAARIAGDERAKAIQLAIEYDPQPPFDSGDRATASTST  200


>gi|343924457|ref|ZP_08764006.1| putative ThiJ/PfpI family protein [Gordonia alkanivorans NBRC 
16433]
 gi|343765601|dbj|GAA10932.1| putative ThiJ/PfpI family protein [Gordonia alkanivorans NBRC 
16433]
Length=240

 Score =  146 bits (368),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 82/177 (47%), Positives = 110/177 (63%), Gaps = 2/177 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +V FV H  G V +D+ +L +    +FDE   PD+++ PGG G      D+ +LDW
Sbjct  27   LPDAEVRFVTHEAGPVVADSGVLLIGATHSFDETPSPDLILVPGGPGCFGAAKDEKLLDW  86

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVP-QRVVEHLP  119
            +R        TTSVCTG +VLAAAGLL+GL ATTHW      +  G   VP +R+V   P
Sbjct  87   LRAVSPGAQWTTSVCTGSVVLAAAGLLDGLRATTHWSSLAALSLYGVTAVPDERIVRAGP  146

Query  120  -ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPAT  175
             ER++TAAGVS+GID+ L L + +   + AEA QL IEYDPQP +D+G  +KAS  T
Sbjct  147  DERIVTAAGVSAGIDLALWLADEIAGTKKAEAIQLAIEYDPQPHLDSGHRSKASAGT  203


>gi|333919956|ref|YP_004493537.1| ThiJ/PfpI domain-containing protein [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333482177|gb|AEF40737.1| ThiJ/PfpI domain protein [Amycolicicoccus subflavus DQS3-9A1]
Length=259

 Score =  146 bits (368),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 78/183 (43%), Positives = 111/183 (61%), Gaps = 2/183 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPG-GIGTRTLIHDQTVLD  59
            +P  ++ FV    G V +D+ +  +    +FDE   PD+V+  G G  + T+  +Q +L+
Sbjct  26   IPGAELRFVWTEPGPVIADSGVFVMAATHSFDETPAPDIVLIGGSGAASGTIAKNQQLLE  85

Query  60   WVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLP  119
            W+R  H  T  T SVCTG +VLAAAGLL+G  ATTHW    +   LGA+ +    + H  
Sbjct  86   WMRRVHETTQWTASVCTGSVVLAAAGLLDGKPATTHWSEMSVLKGLGAQAINDERIVHT-  144

Query  120  ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLA  179
             +++T AGVS+GID+ L LV  +   + A A+QL+IEYDPQPP D+GSL KA+ AT R  
Sbjct  145  GKIVTGAGVSAGIDLALWLVGRIAGDDVARAAQLVIEYDPQPPYDSGSLQKATAATKRGV  204

Query  180  LEF  182
              F
Sbjct  205  AAF  207


>gi|118471850|ref|YP_885501.1| isonitrile hydratase [Mycobacterium smegmatis str. MC2 155]
 gi|118173137|gb|ABK74033.1| isonitrile hydratase, putative [Mycobacterium smegmatis str. 
MC2 155]
Length=243

 Score =  145 bits (366),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 77/176 (44%), Positives = 102/176 (58%), Gaps = 0/176 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +V FV H  G V +D+ +L +     FDE   PDVV+ PGG G+     D+ VL W
Sbjct  26   LPDAEVRFVWHEPGPVTADSGVLMVGATHTFDETPSPDVVLVPGGPGSSAAARDERVLAW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R  H       SVC+G +VLAAAGLL+G  AT+HW         G   V    +    +
Sbjct  86   LRAVHPTANWVASVCSGSMVLAAAGLLDGKRATSHWGALSALKMCGVTAVSDERIVRADD  145

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATH  176
            +VITAAGVS+GID+G+ L   +     A+A QL+IEYDPQPP DAG ++KAS  T 
Sbjct  146  KVITAAGVSAGIDLGMWLAGQIAGEAKAKAIQLLIEYDPQPPFDAGHMSKASATTK  201


>gi|317130619|ref|YP_004096901.1| ThiJ/PfpI domain-containing protein [Bacillus cellulosilyticus 
DSM 2522]
 gi|315475567|gb|ADU32170.1| ThiJ/PfpI domain-containing protein [Bacillus cellulosilyticus 
DSM 2522]
Length=232

 Score =  143 bits (360),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 70/176 (40%), Positives = 108/176 (62%), Gaps = 3/176 (1%)

Query  5    DVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGG-IGTRTLIHDQTVLDWVRE  63
            +V FVG +RGE+++D+  +      + D++   D++I PG  +     + ++ VL W+R+
Sbjct  30   EVFFVGEKRGEIKADSGFIDFNAKYSIDDIHDADILIIPGSPVAFLKEMKNEKVLSWIRQ  89

Query  64   AHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVI  123
              + T  TTSVCTG ++LAA GLL+GL AT+HW++ DL +   A    +RVVE    + I
Sbjct  90   LDKQTKWTTSVCTGSIILAATGLLSGLKATSHWKIIDLLSDFDAIPTRERVVEQ--GKYI  147

Query  124  TAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLA  179
            TAAGVSSG+DM L L   +      +A QL IEYDPQP  ++G+ + +  A  ++A
Sbjct  148  TAAGVSSGVDMALYLTNKIAGDLETKAIQLTIEYDPQPMFNSGNYSSSDKAVIQVA  203


>gi|167461180|ref|ZP_02326269.1| 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Paenibacillus larvae subsp. larvae BRL-230010]
 gi|322383250|ref|ZP_08057059.1| hypothetical protein PL1_1911 [Paenibacillus larvae subsp. larvae 
B-3650]
 gi|321152471|gb|EFX45259.1| hypothetical protein PL1_1911 [Paenibacillus larvae subsp. larvae 
B-3650]
Length=218

 Score =  143 bits (360),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 76/185 (42%), Positives = 112/185 (61%), Gaps = 5/185 (2%)

Query  5    DVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGG--IGTRTLIHDQTVLDWVR  62
            +V  V   +G ++ D+ M  L  D +  E+T  D+++ PG      ++ I+D+ +L+W+R
Sbjct  30   EVKLVAKNKGLIKLDSKMGYLHADFSISEVTSADILVVPGCRPPNYKSPINDKDILNWIR  89

Query  63   EAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERV  122
            + H  T  TTSVCTG L+L AAGLLNGL AT+HW   DL +S GA    +RVV     ++
Sbjct  90   QIHETTKWTTSVCTGSLILGAAGLLNGLKATSHWSCLDLLHSYGAISTNERVVRQ--GKI  147

Query  123  ITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKA-SPATHRLALE  181
            IT+AGVSSGIDM L+LV      +  +  QL++EYDP PP D+GS  K  +P   +L + 
Sbjct  148  ITSAGVSSGIDMALQLVAWESGEDIGKYVQLILEYDPMPPFDSGSPEKVPTPLIEQLKVA  207

Query  182  FYQHR  186
              + +
Sbjct  208  IQEVK  212


>gi|126650641|ref|ZP_01722864.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Bacillus sp. B14905]
 gi|126592797|gb|EAZ86796.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Bacillus sp. B14905]
Length=218

 Score =  142 bits (359),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 73/168 (44%), Positives = 105/168 (63%), Gaps = 4/168 (2%)

Query  6    VVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGI--GTRTLIHDQTVLDWVRE  63
            V FV   +G ++ D+ M  L  D +F ++T  D++I PG      +  ++D+T L+W+R 
Sbjct  31   VKFVAKDKGLIKLDSKMGFLHADYSFSDITSADILIVPGCSPPNFKNPMNDETTLNWIRN  90

Query  64   AHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERVI  123
             H+ T  TTSVC G L+L+AAGLL G+ AT+HW   D+  SLG     +RVV     +++
Sbjct  91   IHQTTKWTTSVCNGSLILSAAGLLKGMKATSHWGSFDILQSLGTIPTDERVVRQ--NKMV  148

Query  124  TAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKA  171
            TAAGVSSGIDM L+LV      + +   QL++EYDPQPP + GS+ KA
Sbjct  149  TAAGVSSGIDMALQLVAWEFGDDLSMGVQLILEYDPQPPFNTGSVQKA  196


>gi|302541561|ref|ZP_07293903.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces hygroscopicus ATCC 53653]
 gi|302459179|gb|EFL22272.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces himastatinicus ATCC 53653]
Length=210

 Score =  142 bits (357),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 80/171 (47%), Positives = 102/171 (60%), Gaps = 2/171 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P    VFV  RRG VR+D+  L L+ +A  +E+ RPDVV+ PGG        +  VL W
Sbjct  26   LPGAQPVFVAERRGPVRNDSGSLQLVAEATLEEVARPDVVLVPGGPFPAEQQKNPEVLAW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R     T  TTSVCTG L+L +AGLL G  ATTHW   D   +LG   V +R V     
Sbjct  86   LRAVDATTTWTTSVCTGSLILGSAGLLTGRRATTHWTAMDDLRALGVEAVDERYV--FDG  143

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKA  171
            + +TAAGVS+GIDMGL L   +     A+  QLM++YDPQPP D+GS  KA
Sbjct  144  KYVTAAGVSAGIDMGLALAGRIAGDATAQTVQLMLQYDPQPPYDSGSPHKA  194


>gi|169628040|ref|YP_001701689.1| hypothetical protein MAB_0943 [Mycobacterium abscessus ATCC 19977]
 gi|169240007|emb|CAM61035.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=259

 Score =  142 bits (357),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 78/169 (47%), Positives = 100/169 (60%), Gaps = 1/169 (0%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  +V FV H  G V +D+ +L +    +F E   PDVV+ PGG GT     D  +LDW
Sbjct  31   IPDTEVRFVWHEPGPVTADSGVLVIGATHSFGETPAPDVVLVPGGPGTTMAARDDKLLDW  90

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYV-PQRVVEHLP  119
            +R  H     TTSVC+G LVLAAAGLL G  AT+HW    L    G   V  +R+V    
Sbjct  91   LRRVHPAAAWTTSVCSGSLVLAAAGLLEGQRATSHWSTLPLLKPFGVTPVGDERIVRTGH  150

Query  120  ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSL  168
              ++TAAGVS+GID+GL L   +   E A+A QL IEYDPQPP D+G +
Sbjct  151  AGLVTAAGVSAGIDLGLWLAGQIAGEERAKAIQLSIEYDPQPPFDSGHM  199


>gi|159898619|ref|YP_001544866.1| ThiJ/PfpI domain-containing protein [Herpetosiphon aurantiacus 
DSM 785]
 gi|159891658|gb|ABX04738.1| ThiJ/PfpI domain protein [Herpetosiphon aurantiacus DSM 785]
Length=231

 Score =  141 bits (356),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 77/176 (44%), Positives = 104/176 (60%), Gaps = 4/176 (2%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  DV FV  ++G + +D   L L+  A +DEL  P VV+ PGG GT   +  Q +L+W
Sbjct  42   LPDTDVYFVADQQGPIYADTGQLALVATATWDELPHPTVVVIPGGAGTMQALAHQPLLNW  101

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSL-GARYVPQRVVEHLP  119
            ++ A       TSVCTG  VL AAGLL+GL  T+HW  ++  +    A Y  +R ++   
Sbjct  102  LQTAAPTVEWMTSVCTGVFVLGAAGLLHGLQVTSHWTSREFIHQYCAATYTAERFIQQ--  159

Query  120  ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVD-AGSLAKASPA  174
              +ITAAGVS+GIDM L L + L S + A+A QL IEYDPQPP   AG   +A  A
Sbjct  160  GNIITAAGVSAGIDMALFLAQQLSSSQTAQAIQLAIEYDPQPPFSGAGDFQQADQA  215


>gi|29828208|ref|NP_822842.1| 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces avermitilis MA-4680]
 gi|29605310|dbj|BAC69377.1| putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Streptomyces avermitilis MA-4680]
Length=211

 Score =  141 bits (355),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 84/171 (50%), Positives = 106/171 (62%), Gaps = 2/171 (1%)

Query  1    VPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGGIGTRTLIHDQTVLDW  60
            +P  + VFV  R G VR+D   L L  D +  E+  PD+V+ PGG G    + +  +LDW
Sbjct  26   LPGAETVFVAERTGPVRADTGALALTADKSLAEVPSPDLVVVPGGPGQTAQMENGVLLDW  85

Query  61   VREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPE  120
            +R A   +  TTSVCTG L+LAAAGLL G  AT+HW   DL +  GA    +RVV     
Sbjct  86   LRAADASSTWTTSVCTGSLLLAAAGLLKGRRATSHWLALDLLDRFGAAPTGERVV--FDG  143

Query  121  RVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKA  171
            + +TAAGVSSGIDMGL L+  +   E A+A QL+ EYDPQPP DAGS  KA
Sbjct  144  KYVTAAGVSSGIDMGLALLGRIAGDEHAQAVQLLTEYDPQPPYDAGSPQKA  194


>gi|167461306|ref|ZP_02326395.1| 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis 
enzyme [Paenibacillus larvae subsp. larvae BRL-230010]
 gi|322381329|ref|ZP_08055332.1| hypothetical protein PL1_0243 [Paenibacillus larvae subsp. larvae 
B-3650]
 gi|321154905|gb|EFX47176.1| hypothetical protein PL1_0243 [Paenibacillus larvae subsp. larvae 
B-3650]
Length=218

 Score =  141 bits (355),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 72/168 (43%), Positives = 104/168 (62%), Gaps = 4/168 (2%)

Query  5    DVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPGG--IGTRTLIHDQTVLDWVR  62
            +V  V   +G ++ D+ M  L  D +  E+   D+++ PG      ++ I+D+ +++W+R
Sbjct  30   EVKLVAKNKGLIKLDSKMGYLHADFSISEVNSADILVVPGSRPPNYKSPINDKDIMNWIR  89

Query  63   EAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFNSLGARYVPQRVVEHLPERV  122
            + H  T  TTSVCTG L+L AAGLLNGL AT+HW   DL +S GA    +RVV     ++
Sbjct  90   QIHETTNWTTSVCTGSLILGAAGLLNGLNATSHWSCLDLLHSYGAISTNERVVRQ--GKI  147

Query  123  ITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAK  170
            IT+AGVSSGIDM L+LV      + ++  QL++EYDP PP D GS  K
Sbjct  148  ITSAGVSSGIDMALQLVAWESGEDISKYVQLILEYDPMPPFDWGSPEK  195



Lambda     K      H
   0.322    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 180588168880




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40