BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0066c Length=745 Score E Sequences producing significant alignments: (Bits) Value gi|15607208|ref|NP_214580.1| isocitrate dehydrogenase [Mycobacte... 1547 0.0 gi|31791243|ref|NP_853736.1| isocitrate dehydrogenase [NADP] [My... 1545 0.0 gi|340625100|ref|YP_004743552.1| putative isocitrate dehydrogena... 1545 0.0 gi|289445594|ref|ZP_06435338.1| isocitrate dehydrogenase [NADP] ... 1545 0.0 gi|339630149|ref|YP_004721791.1| isocitrate dehydrogenase [NADP]... 1543 0.0 gi|183980192|ref|YP_001848483.1| isocitrate dehydrogenase [NADP]... 1407 0.0 gi|118619964|ref|YP_908296.1| isocitrate dehydrogenase [NADP] Ic... 1404 0.0 gi|240168808|ref|ZP_04747467.1| isocitrate dehydrogenase [NADP] ... 1344 0.0 gi|15828442|ref|NP_302705.1| isocitrate dehydrogenase [Mycobacte... 1336 0.0 gi|194307288|gb|ACF42139.1| isocitrate dehydrogenase [Mycobacter... 1326 0.0 gi|111017639|ref|YP_700611.1| isocitrate dehydrogenase (NADP+) [... 1326 0.0 gi|333922112|ref|YP_004495693.1| isocitrate dehydrogenase [NADP]... 1325 0.0 gi|317506897|ref|ZP_07964669.1| monomeric isocitrate dehydrogena... 1323 0.0 gi|296393726|ref|YP_003658610.1| NADP-dependent isocitrate dehyd... 1320 0.0 gi|254776745|ref|ZP_05218261.1| isocitrate dehydrogenase, NADP-d... 1317 0.0 gi|118463374|ref|YP_883450.1| isocitrate dehydrogenase, NADP-dep... 1316 0.0 gi|254820257|ref|ZP_05225258.1| isocitrate dehydrogenase, NADP-d... 1316 0.0 gi|41409554|ref|NP_962390.1| Icd2 [Mycobacterium avium subsp. pa... 1315 0.0 gi|296168844|ref|ZP_06850516.1| isocitrate dehydrogenase [Mycoba... 1312 0.0 gi|342861560|ref|ZP_08718207.1| isocitrate dehydrogenase, NADP-d... 1311 0.0 gi|226364172|ref|YP_002781954.1| isocitrate dehydrogenase [Rhodo... 1306 0.0 gi|262202444|ref|YP_003273652.1| isocitrate dehydrogenase, NADP-... 1306 0.0 gi|194292372|ref|YP_002008279.1| isocitrate dehydrogenase [nadp]... 1305 0.0 gi|118465799|ref|YP_884223.1| isocitrate dehydrogenase, NADP-dep... 1292 0.0 gi|120404190|ref|YP_954019.1| isocitrate dehydrogenase [Mycobact... 1291 0.0 gi|126433838|ref|YP_001069529.1| isocitrate dehydrogenase, NADP-... 1290 0.0 gi|116695867|ref|YP_841443.1| isocitrate dehydrogenase [NADP] [R... 1286 0.0 gi|339323186|ref|YP_004682080.1| hypothetical protein CNE_2c1892... 1284 0.0 gi|333991827|ref|YP_004524441.1| isocitrate dehydrogenase [Mycob... 1281 0.0 gi|108798180|ref|YP_638377.1| isocitrate dehydrogenase, NADP-dep... 1278 0.0 gi|118467432|ref|YP_886031.1| isocitrate dehydrogenase, NADP-dep... 1276 0.0 gi|295675933|ref|YP_003604457.1| isocitrate dehydrogenase, NADP-... 1271 0.0 gi|209516114|ref|ZP_03264973.1| isocitrate dehydrogenase, NADP-d... 1269 0.0 gi|169630765|ref|YP_001704414.1| isocitrate dehydrogenase [Mycob... 1268 0.0 gi|94312661|ref|YP_585870.1| isocitrate dehydrogenase [Cupriavid... 1266 0.0 gi|21615534|emb|CAD32551.1| isocitrate dehydrogenase isozyme 2 [... 1266 0.0 gi|186474237|ref|YP_001861579.1| isocitrate dehydrogenase, NADP-... 1264 0.0 gi|343927284|ref|ZP_08766760.1| isocitrate dehydrogenase [Gordon... 1264 0.0 gi|73538031|ref|YP_298398.1| isocitrate dehydrogenase NADP-depen... 1262 0.0 gi|145224040|ref|YP_001134718.1| isocitrate dehydrogenase, NADP-... 1260 0.0 gi|296139966|ref|YP_003647209.1| isocitrate dehydrogenase, NADP-... 1250 0.0 gi|56475870|ref|YP_157459.1| isocitrate dehydrogenase isozyme 2,... 1246 0.0 gi|338975141|ref|ZP_08630496.1| isocitrate dehydrogenase (NADP) ... 1236 0.0 gi|326382779|ref|ZP_08204469.1| isocitrate dehydrogenase, NADP-d... 1231 0.0 gi|169632785|ref|YP_001706521.1| isocitrate dehydrogenase [Acine... 1225 0.0 gi|119897437|ref|YP_932650.1| isocitrate dehydrogenase [Azoarcus... 1225 0.0 gi|169795135|ref|YP_001712928.1| isocitrate dehydrogenase [Acine... 1224 0.0 gi|260556623|ref|ZP_05828841.1| monomeric isocitrate dehydrogena... 1224 0.0 gi|319950242|ref|ZP_08024169.1| isocitrate dehydrogenase, NADP-d... 1222 0.0 gi|293609787|ref|ZP_06692089.1| isocitrate dehydrogenase [Acinet... 1221 0.0 >gi|15607208|ref|NP_214580.1| isocitrate dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15839445|ref|NP_334482.1| isocitrate dehydrogenase, NADP-dependent, monomeric type [Mycobacterium tuberculosis CDC1551] gi|148659826|ref|YP_001281349.1| isocitrate dehydrogenase (NADP) Icd2 [Mycobacterium tuberculosis H37Ra] 61 more sequence titles Length=745 Score = 1547 bits (4005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 745/745 (100%), Positives = 745/745 (100%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ Sbjct 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE Sbjct 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS Sbjct 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD Sbjct 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA Sbjct 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDSDMTTAVMRPSKTFNAALEAVQG Sbjct 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 >gi|31791243|ref|NP_853736.1| isocitrate dehydrogenase [NADP] [Mycobacterium bovis AF2122/97] gi|121635977|ref|YP_976200.1| putative isocitrate dehydrogenase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988450|ref|YP_002643137.1| putative isocitrate dehydrogenase [Mycobacterium bovis BCG str. Tokyo 172] 6 more sequence titles Length=745 Score = 1545 bits (4000), Expect = 0.0, Method: Compositional matrix adjust. Identities = 744/745 (99%), Positives = 744/745 (99%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADP TDQ Sbjct 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPNTDQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE Sbjct 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS Sbjct 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD Sbjct 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA Sbjct 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDSDMTTAVMRPSKTFNAALEAVQG Sbjct 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 >gi|340625100|ref|YP_004743552.1| putative isocitrate dehydrogenase [NADP] ICD2 [Mycobacterium canettii CIPT 140010059] gi|340003290|emb|CCC42407.1| putative isocitrate dehydrogenase [NADP] ICD2 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) [Mycobacterium canettii CIPT 140010059] Length=745 Score = 1545 bits (3999), Expect = 0.0, Method: Compositional matrix adjust. Identities = 743/745 (99%), Positives = 745/745 (100%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ Sbjct 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKSMTL+RARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE Sbjct 181 GDFYAGEKSMTLNRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFD+LGVNVNNGLS Sbjct 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD Sbjct 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA Sbjct 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDSDMTTAVMRPSKTFNAALEAVQG Sbjct 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 >gi|289445594|ref|ZP_06435338.1| isocitrate dehydrogenase [NADP] icd2 [Mycobacterium tuberculosis CPHL_A] gi|289418552|gb|EFD15753.1| isocitrate dehydrogenase [NADP] icd2 [Mycobacterium tuberculosis CPHL_A] Length=745 Score = 1545 bits (3999), Expect = 0.0, Method: Compositional matrix adjust. Identities = 744/745 (99%), Positives = 744/745 (99%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ Sbjct 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE Sbjct 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS Sbjct 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVE GDIWRMCIVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEVGDIWRMCIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD Sbjct 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA Sbjct 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDSDMTTAVMRPSKTFNAALEAVQG Sbjct 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 >gi|339630149|ref|YP_004721791.1| isocitrate dehydrogenase [NADP] [Mycobacterium africanum GM041182] gi|339329505|emb|CCC25140.1| putative isocitrate dehydrogenase [NADP] Icd2 [Mycobacterium africanum GM041182] Length=745 Score = 1543 bits (3995), Expect = 0.0, Method: Compositional matrix adjust. Identities = 743/745 (99%), Positives = 744/745 (99%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADP TDQ Sbjct 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPNTDQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE Sbjct 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS Sbjct 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDVATGE+LLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVATGEMLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD Sbjct 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA Sbjct 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDSDMTTAVMRPSKTFNAALEAVQG Sbjct 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 >gi|183980192|ref|YP_001848483.1| isocitrate dehydrogenase [NADP] Icd2 [Mycobacterium marinum M] gi|183173518|gb|ACC38628.1| isocitrate dehydrogenase [NADP] Icd2 [Mycobacterium marinum M] Length=745 Score = 1407 bits (3641), Expect = 0.0, Method: Compositional matrix adjust. Identities = 666/745 (90%), Positives = 707/745 (95%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEFPDYLT+ Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIQIKTSDISVAARILAEFPDYLTD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELG LTQ PDTNIIKLPNISASVPQL AAIKELQDKGYA+PDYPADPKTD+ Sbjct 61 EQRVPDNLAELGELTQDPDTNIIKLPNISASVPQLKAAIKELQDKGYAIPDYPADPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKA+KERYARCLGSAVNPVLRQGNSDRRAP AVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKALKERYARCLGSAVNPVLRQGNSDRRAPNAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKS+TLDRA V+MEL+ K G+T+VLKPEV LDDGD+IDSMFMSKKALC+FYEE Sbjct 181 GDFYAGEKSITLDRAHKVKMELVTKGGQTLVLKPEVSLDDGDIIDSMFMSKKALCEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q++DA++TGVMFSLHVKATMMKVSHPIVFGHAV+ FY+DAFAKHQ+LFD+LGVNVNNGLS Sbjct 241 QIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYRDAFAKHQKLFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE+LPASQ DEII+DLHRCHEHRPELAMVDSARGI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIETLPASQHDEIIDDLHRCHEHRPELAMVDSARGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+PEDGVANIVD+ TGEVLLT++VEAGDIWRMC+VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEVPEDGVANIVDLDTGEVLLTQDVEAGDIWRMCVVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPVLFWLDPYRPHENELIKKVKTYLKDH TEGLDIQIMSQVRSMRYT ERL+RGLD Sbjct 481 RNSGMPVLFWLDPYRPHENELIKKVKTYLKDHHTEGLDIQIMSQVRSMRYTLERLIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA ED+GIK GN+RAK+L +TLD AIGKLL N+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGASLEDMGIKIGNDRAKILARTLDDAIGKLLGNNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELA QTDD +LAEHFA LA L E+ IV EL E QGE VDIGGYYA Sbjct 661 GSQFYLALYWAQELAEQTDDAELAEHFAKLAKALADGEEAIVAELAEAQGEAVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PD++ TTAVMRPSKT NAALEA QG Sbjct 721 PDNEKTTAVMRPSKTLNAALEAAQG 745 >gi|118619964|ref|YP_908296.1| isocitrate dehydrogenase [NADP] Icd2 [Mycobacterium ulcerans Agy99] gi|118572074|gb|ABL06825.1| isocitrate dehydrogenase [NADP] Icd2 [Mycobacterium ulcerans Agy99] Length=745 Score = 1404 bits (3635), Expect = 0.0, Method: Compositional matrix adjust. Identities = 664/745 (90%), Positives = 706/745 (95%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SD+SVAARILAEFPDYLT+ Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIQIKTSDVSVAARILAEFPDYLTD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELG LTQ PDTNIIKLPNISASVPQL AAIKELQDKGYA+PDYPADPKTD+ Sbjct 61 EQRVPDNLAELGELTQDPDTNIIKLPNISASVPQLKAAIKELQDKGYAIPDYPADPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKA+KERYARCLGSAVNPVLRQGNSDRRAP AVKEYARKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKALKERYARCLGSAVNPVLRQGNSDRRAPNAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKS+TLDRA V+MEL+ K G+T+VLKPEV LDDGD+IDSMFMSKKALC+FYEE Sbjct 181 GDFYAGEKSITLDRAHKVKMELVTKGGQTLVLKPEVSLDDGDIIDSMFMSKKALCEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q++DA++TGVMFSLHVKATMMKVSHPIVFGHAV+ FY+DAFAKHQ+LFD+LGVNVNNGLS Sbjct 241 QIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYRDAFAKHQKLFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE+LPASQ DEII+DLHRCHEHRPELAMVDSARGI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIETLPASQHDEIIDDLHRCHEHRPELAMVDSARGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+PEDGVANIVD+ TGEVLLT++VEAGDIWRMC+VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEVPEDGVANIVDLDTGEVLLTQDVEAGDIWRMCVVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPVLFWLDPYRPHENELIKKVKTYLKDH TEGLDIQIMSQVRSMRYT ERL+RGLD Sbjct 481 RNSGMPVLFWLDPYRPHENELIKKVKTYLKDHHTEGLDIQIMSQVRSMRYTLERLIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA ED+G K GN+RAK+L +TLD AIGKLL N+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGASLEDMGTKIGNDRAKILARTLDDAIGKLLGNNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELA QTDD +LAEHFA LA L E+ IV EL E QGE VDIGGYYA Sbjct 661 GSQFYLALYWAQELAEQTDDAELAEHFAKLAKALADGEEAIVAELAEAQGEAVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PD++ TTAVMRPSKT NAALEA QG Sbjct 721 PDNEKTTAVMRPSKTLNAALEAAQG 745 >gi|240168808|ref|ZP_04747467.1| isocitrate dehydrogenase [NADP] icd2 [Mycobacterium kansasii ATCC 12478] Length=745 Score = 1344 bits (3479), Expect = 0.0, Method: Compositional matrix adjust. Identities = 640/745 (86%), Positives = 690/745 (93%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS EQPTIIYTLTDEAPLLATYAFLPI+RAFAEPAGIKI++SDIS+A+RILAEFPDYLTE Sbjct 1 MSDEQPTIIYTLTDEAPLLATYAFLPILRAFAEPAGIKIKSSDISLASRILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 +QRVPD+LAELGRLTQLP+TNIIKLPNISASVPQLV+AIKELQ KGY +PDYPADPKTD+ Sbjct 61 DQRVPDDLAELGRLTQLPETNIIKLPNISASVPQLVSAIKELQGKGYKLPDYPADPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK I+ RYA+CLGSAVNPVLR+GNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVA M+H Sbjct 121 EKDIRNRYAKCLGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL+ KSG+T+VLKP+V L +GD+IDSMFMSKKAL +FYEE Sbjct 181 GDFYHGEKSMTLDRARDVKMELVTKSGETLVLKPKVSLGEGDIIDSMFMSKKALVEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVMFSLHVKATMMK+SHPIVFGHAVR FYKDAFAKHQELFD+LGVNVNNGL Sbjct 241 QMEDARKTGVMFSLHVKATMMKISHPIVFGHAVRTFYKDAFAKHQELFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY+KIESLPAS DEII DLH CHEHRPELAMVDSA+GISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYNKIESLPASLHDEIIRDLHACHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADG+ KDTKAV PESTFSRIYQE+INFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGRPKDTKAVMPESTFSRIYQELINFCKTNGAFDPRTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWRMC V DA IRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMCTVTDAAIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPVLFWLDPYRPHENELIKKVK YL+DH T GLDIQIMSQVR+MRYT ERL+RGLD Sbjct 481 RNSGMPVLFWLDPYRPHENELIKKVKLYLQDHYTNGLDIQIMSQVRAMRYTLERLIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLA+GA +D+G KTGN++AK+LGKTLDAAIGKLLDN+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLAIGASLDDMGAKTGNKKAKILGKTLDAAIGKLLDNNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQ +DQQL EHFA LAD L KNE+ IV EL QG DIGGYYA Sbjct 661 GSQFYLAMYWAQELAAQNEDQQLREHFAPLADSLAKNEETIVAELAAAQGAEADIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PD + TTAVMRPSKTFN AL A G Sbjct 721 PDREKTTAVMRPSKTFNEALTAAPG 745 >gi|15828442|ref|NP_302705.1| isocitrate dehydrogenase [Mycobacterium leprae TN] gi|221230919|ref|YP_002504335.1| isocitrate dehydrogenase [Mycobacterium leprae Br4923] gi|2959398|emb|CAA17935.1| isocitrate dehydrogenase [Mycobacterium leprae] gi|13093872|emb|CAC32204.1| isocitrate dehydrogenase [NADP] [Mycobacterium leprae] gi|219934026|emb|CAR72772.1| isocitrate dehydrogenase [NADP] [Mycobacterium leprae Br4923] Length=746 Score = 1336 bits (3458), Expect = 0.0, Method: Compositional matrix adjust. Identities = 636/745 (86%), Positives = 680/745 (92%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQ TIIYTLTDEAPLLATYAFLPIVRAF +PAGIK++ SDISVAARILAEFPDYLTE Sbjct 1 MSAEQWTIIYTLTDEAPLLATYAFLPIVRAFTKPAGIKVQTSDISVAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVP+NLAELGRLTQLPDTNIIKLPNISASVPQL+AAIKELQ KG+ +PDYP DPK+ Q Sbjct 61 EQRVPNNLAELGRLTQLPDTNIIKLPNISASVPQLMAAIKELQAKGFKLPDYPQDPKSYQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E I+ RY +CLGSAVNPVLR+GNSDRRAPKAVKEYAR +PHSMGEWSMASRTHVA MRH Sbjct 121 EIDIRNRYGKCLGSAVNPVLREGNSDRRAPKAVKEYARNNPHSMGEWSMASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL K GK +VLKP+V L DGD+IDSMFMSKKALC+FYEE Sbjct 181 GDFYHGEKSMTLDRARDVKMELATKKGKIVVLKPKVSLRDGDIIDSMFMSKKALCEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVMFSLHVKATMMKVSHPIVFGHAV+ FYK+AFAKHQ+LFD+LGVNVNNGL Sbjct 241 QMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYKEAFAKHQDLFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE+L ASQRDEII+DLH CHEHRPELAMVDSARGISNF+SPSDVIVDASMPAMIR Sbjct 301 DLYSKIETLTASQRDEIIQDLHACHEHRPELAMVDSARGISNFYSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKTNG FDP TMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGRAKDTKAVNPESTFSRIYQEIINFCKTNGAFDPATMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWR+C+V DA IRDWVKLAV+R Sbjct 421 EYGSHDKTFEIPEDGVANIVDLTTGEVLLTQNVETGDIWRLCVVTDAAIRDWVKLAVSRM 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPVLFWLDPYRPHENELIKKV+ YLKDHDT GLDIQIMSQVRSMRYTCERL+RGLD Sbjct 481 RNSGMPVLFWLDPYRPHENELIKKVRAYLKDHDTSGLDIQIMSQVRSMRYTCERLIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGNERAK+L KTLD A GKLLDN KSPSRK GELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDLGIKTGNERAKILAKTLDVATGKLLDNRKSPSRKAGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA QTDDQ L +F LA+ L KNE IV EL E QG+ VDIGGYYA Sbjct 661 GSQFYLAMYWAQELATQTDDQHLRNYFTPLAETLAKNECTIVAELNEAQGKAVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PD+++ AVMRPS FNAAL A QG Sbjct 721 PDAELAKAVMRPSAVFNAALAAAQG 745 >gi|194307288|gb|ACF42139.1| isocitrate dehydrogenase [Mycobacterium lepromatosis] Length=741 Score = 1326 bits (3433), Expect = 0.0, Method: Compositional matrix adjust. Identities = 626/736 (86%), Positives = 670/736 (92%), Gaps = 0/736 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAF +PAGIKI+ SDIS+AARILAEFPDYLTE Sbjct 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFTKPAGIKIQTSDISLAARILAEFPDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQLPDTNI+KLPNISASVPQL+AAIKELQ KG+ +PDYP PK+DQ Sbjct 61 EQRVPDNLAELGRLTQLPDTNIVKLPNISASVPQLMAAIKELQAKGFKLPDYPPSPKSDQ 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E I+ RY +CLGSAVNPVLR+GNSDRR PK VKEYAR +PHSMGEWSMASRTHVA MRH Sbjct 121 EIDIRNRYGKCLGSAVNPVLREGNSDRRVPKVVKEYARNNPHSMGEWSMASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL K GKT+VLKP+V L DGD+IDSMFMSKKALC+FYEE Sbjct 181 GDFYHGEKSMTLDRARDVKMELATKKGKTVVLKPKVSLRDGDIIDSMFMSKKALCEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVMFSLHVKATMMKVSHPIVFGHAV+ FYK+AF KHQ LF +LGVNVNNGL Sbjct 241 QMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYKEAFTKHQALFGELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKI +LPASQRDEII+DLH CHEHRPELAMVDSA GISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIRTLPASQRDEIIQDLHACHEHRPELAMVDSALGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKTNG FDP TMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGRTKDTKAVNPESTFSRIYQEIINFCKTNGAFDPATMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+PEDGVANIVD+ TGEVLLT+NVE GDIWR+C+V DA IRDWVKLAVTRA Sbjct 421 EYGSHDKTFEVPEDGVANIVDLVTGEVLLTQNVETGDIWRLCVVTDAAIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 S MPVLFWLDPYRPHENELIKKV+ YLKDHDT GLDIQIMSQVRSMRYTCERL+RGL+ Sbjct 481 CNSDMPVLFWLDPYRPHENELIKKVRAYLKDHDTSGLDIQIMSQVRSMRYTCERLIRGLN 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VP+MAGGGMYETGAGGSAPKHVKQ VEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPMMAGGGMYETGAGGSAPKHVKQFVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGNERAK+L KTLDAA GKLL+N KSPSRK GELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDLGIKTGNERAKVLAKTLDAATGKLLENRKSPSRKAGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA QTDDQQL HF LA+ L KNE IV EL E QG+ VDIGGYYA Sbjct 661 GSQFYLAMYWAQELATQTDDQQLRNHFTPLAETLAKNEYTIVTELNEDQGKAVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTF 736 PD+++T AVMRPS F Sbjct 721 PDAELTKAVMRPSAVF 736 >gi|111017639|ref|YP_700611.1| isocitrate dehydrogenase (NADP+) [Rhodococcus jostii RHA1] gi|110817169|gb|ABG92453.1| isocitrate dehydrogenase (NADP+) [Rhodococcus jostii RHA1] Length=746 Score = 1326 bits (3432), Expect = 0.0, Method: Compositional matrix adjust. Identities = 629/745 (85%), Positives = 684/745 (92%), Gaps = 1/745 (0%) Query 1 MSAEQ-PTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLT 59 MSA++ PTIIYTLTDEAPLLATYAFLPIVR FA AGI++E+SDISV ARILAEFPD LT Sbjct 1 MSADKHPTIIYTLTDEAPLLATYAFLPIVRTFAGAAGIEVESSDISVPARILAEFPDRLT 60 Query 60 EEQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTD 119 EEQRVPDNLAELGRLTQLP+TNIIKLPNISASVPQL+AAIKELQ KGY +PD+P PKTD Sbjct 61 EEQRVPDNLAELGRLTQLPETNIIKLPNISASVPQLLAAIKELQGKGYQIPDFPEAPKTD 120 Query 120 QEKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMR 179 +E+ I++RY R LGSAVNPVLR+GNSDRRAP+AVKEY RKHPHSMGEWSMASR+HVAHMR Sbjct 121 EERDIRQRYGRILGSAVNPVLREGNSDRRAPRAVKEYVRKHPHSMGEWSMASRSHVAHMR 180 Query 180 HGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYE 239 HGDFY GEKSMTLDR R VRMEL+ KSG+TIVLK + L +GD++DSMFMSKKAL DFYE Sbjct 181 HGDFYHGEKSMTLDRQRTVRMELVTKSGETIVLKEGLALGEGDIMDSMFMSKKALLDFYE 240 Query 240 EQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGL 299 EQM+DA +TGVMFSLHVKATMMKVSHPIVFGHAV+ FYKDAFAKHQ+LFD+LGVNVNNGL Sbjct 241 EQMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYKDAFAKHQKLFDELGVNVNNGL 300 Query 300 SDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 359 DLY KIE+LP++QR+EII+DLH CHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI Sbjct 301 VDLYDKIETLPSTQREEIIQDLHDCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 360 Query 360 RAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQA 419 R+GG MYGADG+LKD KAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+A Sbjct 361 RSGGMMYGADGRLKDAKAVMPESTFARIYQEIINFCKTNGAFDPTTMGTVPNVGLMAQKA 420 Query 420 EEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTR 479 EEYGSHDKTFEIPEDG AN VDV TGEVLLT+ VEAGDIWRMC VKDAPIRDWVKLAVTR Sbjct 421 EEYGSHDKTFEIPEDGDANFVDVETGEVLLTQQVEAGDIWRMCTVKDAPIRDWVKLAVTR 480 Query 480 ARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGL 539 AR SGMPVLFWLDPYRPHENELIKKV+ YL+DHDTEGLDIQIMSQVRSMRYT ERL+RG+ Sbjct 481 ARNSGMPVLFWLDPYRPHENELIKKVELYLQDHDTEGLDIQIMSQVRSMRYTLERLIRGM 540 Query 540 DTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEE 599 DTIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEE Sbjct 541 DTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEE 600 Query 600 NHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDN 659 NHLRWDSLGEFLAL FED+GIKTGNE AK+L KTLDAA GKLLD +K+PSRKTGELDN Sbjct 601 NHLRWDSLGEFLALAVSFEDLGIKTGNEHAKILAKTLDAATGKLLDENKNPSRKTGELDN 660 Query 660 RGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYY 719 RGSQFYLA+YWAQELAAQT+D++LAE FA+LA+ LT+NE+ IVREL EVQG PVDIGGYY Sbjct 661 RGSQFYLALYWAQELAAQTEDKELAERFATLAEALTENEETIVRELIEVQGSPVDIGGYY 720 Query 720 APDSDMTTAVMRPSKTFNAALEAVQ 744 PDS+ AVMRPSKT N L A Q Sbjct 721 QPDSEKADAVMRPSKTLNTTLAAAQ 745 >gi|333922112|ref|YP_004495693.1| isocitrate dehydrogenase [NADP] [Amycolicicoccus subflavus DQS3-9A1] gi|333484333|gb|AEF42893.1| Isocitrate dehydrogenase [NADP] [Amycolicicoccus subflavus DQS3-9A1] Length=745 Score = 1325 bits (3428), Expect = 0.0, Method: Compositional matrix adjust. Identities = 629/743 (85%), Positives = 683/743 (92%), Gaps = 0/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA+QPTIIYTLTDEAPLLAT AFLPI+R F + AGIKIE SDISVAARILAEFPDYLT+ Sbjct 1 MSAQQPTIIYTLTDEAPLLATGAFLPIIRTFTDSAGIKIETSDISVAARILAEFPDYLTD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNL ELGRLTQLP+TNIIKLPNISASVPQLVAAIKELQ KGY +PD+P DPKTD+ Sbjct 61 EQRVPDNLGELGRLTQLPETNIIKLPNISASVPQLVAAIKELQAKGYELPDFPQDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK I++RYA+CLGSAVNPVLR+GNSDRRAPKAVKEY RKHPHSMGEWSMASRTHVAHMRH Sbjct 121 EKEIRDRYAKCLGSAVNPVLREGNSDRRAPKAVKEYVRKHPHSMGEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMT DRA V+MELL +SGKTIVLKPEV L +GD+ DSMFMSKKALCDFYEE Sbjct 181 GDFYHGEKSMTADRACKVKMELLTESGKTIVLKPEVSLGEGDIFDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVMFSLHVKATMMKVSHPIVFGHAVRIFYK+AFAKHQELFD+LGVNVNNGL Sbjct 241 QMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVRIFYKEAFAKHQELFDELGVNVNNGLG 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY KIE+LP+SQRDEII+DLH CHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYDKIETLPSSQRDEIIKDLHECHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 +GGKMYGADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 361 SGGKMYGADGRTKDTKAVIPESTFARIYQEIINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE G ANIVD+ TGEVLLT++VEAGDIWRMC VKD PIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEAGDANIVDLDTGEVLLTQHVEAGDIWRMCTVKDQPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPVLFWLDPYRPHENELIKKV+T LKDHDT GLDIQIMSQVRSMRYT ERL+RGLD Sbjct 481 RDSGMPVLFWLDPYRPHENELIKKVQTCLKDHDTSGLDIQIMSQVRSMRYTLERLIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+G K N++A +L KTLDAA GKLL+N+K+PSRKTGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDVGRKFDNKQAAILAKTLDAATGKLLENNKNPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQ++D L +HFA+LA+ L + E+ IV+EL EVQG+ VDIGG+YA Sbjct 661 GSQFYLALYWAQELAAQSEDADLQKHFAALAEKLAETEETIVQELAEVQGKQVDIGGHYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 PD D +AVMRPSKTF+ AL A Sbjct 721 PDLDKISAVMRPSKTFDDALAAT 743 >gi|317506897|ref|ZP_07964669.1| monomeric isocitrate dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316254825|gb|EFV14123.1| monomeric isocitrate dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=745 Score = 1323 bits (3425), Expect = 0.0, Method: Compositional matrix adjust. Identities = 631/745 (85%), Positives = 681/745 (92%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+A+Q TIIYTLTDEAPLLATYAFLPIVRAFAE AGI ++ SDIS+AARILAEF DYLTE Sbjct 1 MNAQQSTIIYTLTDEAPLLATYAFLPIVRAFAEEAGITVKTSDISLAARILAEFSDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 Q PD+LAELGRLTQLPDTNIIKLPNISASVPQL+AAIKELQ KGYA+PDYP DPKTD+ Sbjct 61 AQHAPDDLAELGRLTQLPDTNIIKLPNISASVPQLLAAIKELQGKGYAIPDYPGDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKA+K RY +CLGSAVNPVLR+GNSDRRAPKAVKEYARKHPHSMG WS ASRTHVA M+H Sbjct 121 EKALKARYGKCLGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGAWSQASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS+TLDRAR+VRMEL+ GKTIVLKP V LD GDVIDSMFMSKKALCDFYEE Sbjct 181 GDFYHGEKSLTLDRARDVRMELVTGGGKTIVLKPLVKLDAGDVIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA++TGVMFSLHVKATMMKVSHPIVFGHAVRIFYK+AFAKHQ+LFD+LGVNVNNGLS Sbjct 241 QMEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVRIFYKEAFAKHQQLFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPAS +EII DLH CHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASLHEEIINDLHACHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDVATGEVLL++NVEA DIWRM +VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLSQNVEAEDIWRMPVVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPV+FWLD RPHENEL KKV TYLK+HDTEGLDI IMSQ R+MR+T ER +RG D Sbjct 481 RNSGMPVVFWLDQERPHENELRKKVNTYLKEHDTEGLDISIMSQERAMRHTIERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHV QL+EEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVSQLIEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA ED+G+KTGN RA +L K LD A GKLLDN+K+PSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGASLEDLGVKTGNARASVLAKALDRATGKLLDNNKNPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA QT+D++L FA LA L +NED+IV+EL +VQG+P DIGGYYA Sbjct 661 GSQFYLAMYWAQELAEQTEDRELQARFAPLAAALAENEDLIVQELADVQGKPTDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 DSD TAVMRPSKTFN + A +G Sbjct 721 ADSDTLTAVMRPSKTFNTIMAAPRG 745 >gi|296393726|ref|YP_003658610.1| NADP-dependent isocitrate dehydrogenase [Segniliparus rotundus DSM 44985] gi|296180873|gb|ADG97779.1| isocitrate dehydrogenase, NADP-dependent [Segniliparus rotundus DSM 44985] Length=745 Score = 1320 bits (3415), Expect = 0.0, Method: Compositional matrix adjust. Identities = 627/744 (85%), Positives = 676/744 (91%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA+QPTIIYTLTDEAPLLAT+AFLPIVR FA+ A I ++ SDIS+AARILAEFPDYL E Sbjct 1 MSAQQPTIIYTLTDEAPLLATHAFLPIVRTFAKEADIVVKTSDISLAARILAEFPDYLAE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QR PD+LAELGRLTQLPDTNIIKLPNISASVPQL+AAIKELQ KGYA+PDYP DPKTD+ Sbjct 61 SQRAPDDLAELGRLTQLPDTNIIKLPNISASVPQLLAAIKELQGKGYAIPDYPGDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E AIK RY +CLGSAVNPVLR+GNSDRRAPKAVKEYARKHPHSMG WS ASRTHVA M+H Sbjct 121 ELAIKTRYGKCLGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGAWSQASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS+TLDRAR+VRMEL+ G+ VLKPEV L GD+IDSMFMSKKALCDFYEE Sbjct 181 GDFYHGEKSLTLDRARDVRMELVNSDGEKTVLKPEVKLLSGDIIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV+IFYKDAFAKHQELFD+LGVNVNNG+S Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKIFYKDAFAKHQELFDELGVNVNNGMS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE LPASQ +EII DLH CHEHRPELAMVDSA+GISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIEKLPASQHEEIIRDLHACHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGRPKDTKAVNPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ATGEVLL++NVEAGDIWRM +VKDAPIRDWVKLAV RA Sbjct 421 EYGSHDKTFEIPEDGVANIVDIATGEVLLSQNVEAGDIWRMPVVKDAPIRDWVKLAVNRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPV+FWLD RPHENEL KKV TYLKDHDTEGLDI IMSQ R+MR+T ER +RG D Sbjct 481 RNSGMPVVFWLDQERPHENELRKKVNTYLKDHDTEGLDISIMSQERAMRHTIERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHVKQL+EEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVKQLIEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+G KTGN RA +L K LDAA G LL N+K+PS KTGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDLGAKTGNTRAAILAKALDAATGTLLGNNKNPSPKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELA+QT+D+QLAE FA++AD L KNE VI+ EL EVQG+PVDIGGYYA Sbjct 661 GSQFYLALYWAQELASQTEDRQLAERFATIADELAKNEAVIIEELAEVQGKPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 SD TAVMRPSKTFNA L A Q Sbjct 721 ASSDTLTAVMRPSKTFNAILSAAQ 744 >gi|254776745|ref|ZP_05218261.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium subsp. avium ATCC 25291] Length=745 Score = 1317 bits (3409), Expect = 0.0, Method: Compositional matrix adjust. Identities = 630/744 (85%), Positives = 679/744 (92%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAE+PT+IYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEFP++LTE Sbjct 1 MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLT+L DTNIIKLPNISASVPQL+AA+KELQ KGY +PD+P PKTD+ Sbjct 61 EQRVPDNLAELGRLTKLADTNIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 ++ I+ERYA+CLGSAVNPVLRQGNSDRRAPKAVKEYARKHPH M EWS ASRTHVA M+H Sbjct 121 DREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHHMAEWSPASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRARNV+MEL KSGKTIVLKP V L GD+IDSMFMSKKAL +FYE+ Sbjct 181 GDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV++FYK+AFAKHQ LFD+LGV+VNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPAS DEII DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASLHDEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKT+G FDP TMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGAFDPATMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWRM IV+D PIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM +FWLD RPHE EL KKVK YLK+HDTEGL IQIM QV +MRYT ER +RG D Sbjct 481 RNSGMTAVFWLDTERPHEVELCKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIA TGNILRDYLTDLFPILELGTSAKMLS+VPLM+GGGMYETGAGGSAPKHV QLVEEN Sbjct 541 TIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FEDIGIKTGN+RAKLLGKTLDAAIGKLL+N+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAIGKLLENNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQ DD +L HFA+LA+ L +NE IV EL EVQG PVDIGGYY Sbjct 661 GSQFYLALYWAQELAAQNDDDELRRHFAALAESLGENEQRIVEELAEVQGRPVDIGGYYQ 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PDS+ TTAVMRPSKTFN AL A Q Sbjct 721 PDSEKTTAVMRPSKTFNEALAASQ 744 >gi|118463374|ref|YP_883450.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium 104] gi|118164661|gb|ABK65558.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium 104] Length=745 Score = 1316 bits (3407), Expect = 0.0, Method: Compositional matrix adjust. Identities = 630/744 (85%), Positives = 679/744 (92%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAE+PT+IYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEFP++LTE Sbjct 1 MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLT+L DTNIIKLPNISASVPQL+AA+KELQ KGY +PD+P PKTD+ Sbjct 61 EQRVPDNLAELGRLTKLADTNIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 ++ I+ERYA+CLGSAVNPVLRQGNSDRRAPKAVKEYARKHPH M EWS ASRTHVA M+H Sbjct 121 DREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHHMAEWSPASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRARNV+MEL KSGKTIVLKP V L GD+IDSMFMSKKAL +FYE+ Sbjct 181 GDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV++FYK+AFAKHQ LFD+LGV+VNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPAS DEII DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASLHDEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKT+G FDP TMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGAFDPATMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWRM IV+D PIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM +FWLD RPHE EL KKVK YLK+HDTEGL IQIM QV +MRYT ER +RG D Sbjct 481 RNSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIA TGNILRDYLTDLFPILELGTSAKMLS+VPLM+GGGMYETGAGGSAPKHV QLVEEN Sbjct 541 TIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FEDIGIKTGN+RAKLLGKTLDAAIGKLL+N+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAIGKLLENNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQ DD +L HFA+LA+ L +NE IV EL EVQG PVDIGGYY Sbjct 661 GSQFYLALYWAQELAAQNDDDELRRHFAALAESLGENEQRIVEELAEVQGRPVDIGGYYQ 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PDS+ TTAVMRPSKTFN AL A Q Sbjct 721 PDSEKTTAVMRPSKTFNEALAASQ 744 >gi|254820257|ref|ZP_05225258.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium intracellulare ATCC 13950] Length=745 Score = 1316 bits (3406), Expect = 0.0, Method: Compositional matrix adjust. Identities = 635/745 (86%), Positives = 682/745 (92%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAE+PT+IYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEFP++LTE Sbjct 1 MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLT+L DTNIIKLPNISASVPQL+AA+KELQ KG+ +PD+P PKTD+ Sbjct 61 EQRVPDNLAELGRLTKLADTNIIKLPNISASVPQLIAAVKELQGKGFKIPDFPQSPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 +K I++RYA+CLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSM WS ASRTHVA MR Sbjct 121 DKEIRDRYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMAPWSPASRTHVATMRG 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRARNV+MEL +SG+TIVLKP V L + DVIDSMFMSKKAL +FYEE Sbjct 181 GDFYHGEKSMTLDRARNVKMELETESGETIVLKPMVSLRNADVIDSMFMSKKALVEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV+IFYK+AFAKHQELFD+LGV+VNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHQELFDELGVDVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPAS +EII DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASLHEEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADG+ KDTKAVNPESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMWGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE GVANIVD+ TGEVLLT+NVEAGDIWRM IV+D IRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEGGVANIVDLDTGEVLLTQNVEAGDIWRMPIVRDEAIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM V+FWLD RPHE EL KKVK YLK+HDTEGLDI IM QV +MRYT ER +RG D Sbjct 481 RNSGMTVVFWLDTERPHEVELRKKVKEYLKEHDTEGLDINIMPQVWAMRYTLERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FEDIGIKT NERAKLLGKTLDAAIGKLLDN+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGACFEDIGIKTDNERAKLLGKTLDAAIGKLLDNNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQ DD+ L E FA+LAD L +NED IV EL EVQGE VDIGGYY Sbjct 661 GSQFYLALYWAQELAAQNDDEDLRERFAALADSLAENEDTIVGELAEVQGESVDIGGYYY 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDS+ TTAVMRPSKTFN L A QG Sbjct 721 PDSEKTTAVMRPSKTFNEVLAAAQG 745 >gi|41409554|ref|NP_962390.1| Icd2 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398385|gb|AAS06006.1| Icd2 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459577|gb|EGO38512.1| isocitrate dehydrogenase, NADP-dependent, monomeric type [Mycobacterium avium subsp. paratuberculosis S397] Length=745 Score = 1315 bits (3403), Expect = 0.0, Method: Compositional matrix adjust. Identities = 630/744 (85%), Positives = 678/744 (92%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAE+PT+IYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEFP++LTE Sbjct 1 MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLT+L DTNIIKLPNISASVPQL+AA+KELQ KGY +PD+P PKTD+ Sbjct 61 EQRVPDNLAELGRLTKLADTNIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 ++ I+ERYA+CLGSAVNPVLRQGNSDRRAPKAVKEYARKHPH M EWS ASRTHVA M+H Sbjct 121 DREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHHMAEWSPASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRARNV+MEL KSGKTIVLKP V L GD+IDSMFMSKKAL +FYE+ Sbjct 181 GDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV++FYK+AFAKHQ LFD+LGV+VNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPAS DEII DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASLHDEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKT+G FDP TMGTVPNVGLMAQQAE Sbjct 361 AGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGAFDPATMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWRM IV+D PIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM +FWLD RPHE EL KKVK YLK+HDTEGL IQIM QV +MRYT ER +RG D Sbjct 481 RNSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIA TGNILRDYLTDLFPILELGTSAKMLS+VPLM+GGGMYETGAGGSAPKHV QLVEEN Sbjct 541 TIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FEDIGIKTGN+RAKLLGKTLDAAIGKLL+N+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAIGKLLENNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQ DD +L HFA+LA L +NE IV EL EVQG PVDIGGYY Sbjct 661 GSQFYLALYWAQELAAQNDDDELRRHFAALAASLGENEQRIVEELAEVQGRPVDIGGYYQ 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PDS+ TTAVMRPSKTFN AL A Q Sbjct 721 PDSEKTTAVMRPSKTFNEALAASQ 744 >gi|296168844|ref|ZP_06850516.1| isocitrate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896461|gb|EFG76111.1| isocitrate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=746 Score = 1312 bits (3395), Expect = 0.0, Method: Compositional matrix adjust. Identities = 629/745 (85%), Positives = 678/745 (92%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPT+IYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEF D LTE Sbjct 1 MSAEQPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFSDCLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLT+LPDTNIIKLPNISASVPQL+AA+KELQ KG+ +PD+P PKTD+ Sbjct 61 EQRVPDNLAELGRLTKLPDTNIIKLPNISASVPQLIAAVKELQGKGFKIPDFPQSPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK I+ RY +CLGSAVNPVLRQGNSDRRAPKAVKEYAR+HPHSMGEWS ASRTHVA MRH Sbjct 121 EKEIRARYGKCLGSAVNPVLRQGNSDRRAPKAVKEYARRHPHSMGEWSPASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRARNV+M L K GKT+ LKP+V L DGDVIDSMFMSKKAL +FYEE Sbjct 181 GDFYHGEKSMTLDRARNVKMVLKTKGGKTLELKPKVELRDGDVIDSMFMSKKALVEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQELFD+LGV+VNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQELFDELGVDVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLPAS +EII DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPASLHEEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADG+ KDTKAVNPESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMWGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVA+IVD+ TGEVLLT+NVE GDIWRM IV D IRDWVKLAV RA Sbjct 421 EYGSHDKTFEIPEDGVADIVDLDTGEVLLTQNVEEGDIWRMPIVTDEAIRDWVKLAVNRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM V+FWLD RPHE EL KKVK YLK+HDTEGLDI IM QV +MRYT ER +RG D Sbjct 481 RASGMTVVFWLDTERPHEVELRKKVKAYLKEHDTEGLDINIMPQVWAMRYTLERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QL+EEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLLEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FEDIG KT NERAK+LGKTLDAAIGKLL+N+KSPSRK GELDNR Sbjct 601 HLRWDSLGEFLALGACFEDIGTKTDNERAKILGKTLDAAIGKLLENNKSPSRKAGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA YWA+ELA Q+DD++L +HFA+LAD L +NED IV EL E QGE VDIGGYY Sbjct 661 GSQFYLARYWAEELANQSDDEELRKHFAALADSLRENEDTIVAELAEAQGETVDIGGYYQ 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PDS+ TTA+MRPSKTFN AL A QG Sbjct 721 PDSEKTTAIMRPSKTFNEALAASQG 745 >gi|342861560|ref|ZP_08718207.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium colombiense CECT 3035] gi|342131049|gb|EGT84338.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium colombiense CECT 3035] Length=744 Score = 1311 bits (3393), Expect = 0.0, Method: Compositional matrix adjust. Identities = 626/745 (85%), Positives = 684/745 (92%), Gaps = 1/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPT+IYTLTDEAPLLATYAFLPIVRAFAEPAGI+I+ SDISVAARILAEFP++LTE Sbjct 1 MSAEQPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLT+L DTNIIKLPN+SASVPQL+AAIKELQ KG+ +PD+P +PKTD+ Sbjct 61 EQRVPDNLAELGRLTKLADTNIIKLPNVSASVPQLIAAIKELQGKGFKIPDFPHNPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 ++ I++RYA+CLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMG+WS ASRTHVA MRH Sbjct 121 DREIRDRYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGKWSQASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRA NV+MEL KSGKTIVLKP V L GD+IDSMFMSKKAL +FYEE Sbjct 181 GDFYHGEKSMTLDRACNVKMELETKSGKTIVLKPMVSLRKGDIIDSMFMSKKALIEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV+IFYKDAFAKH LFD+LGV+VNNGLS Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKIFYKDAFAKHGALFDELGVDVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY KIESLPASQ DEII DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYDKIESLPASQHDEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADG+ KDTKAVNPESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMAQQAE Sbjct 361 AGGKMWGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWRM IV+D PIRDWVKLAV RA Sbjct 421 EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVEEGDIWRMPIVRDEPIRDWVKLAVNRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPV+FWLD RPHENEL KKV TYL +HDT+GLDIQ MSQ R+MR+T ER +RG D Sbjct 481 RNSGMPVVFWLDQERPHENELRKKVNTYLAEHDTDGLDIQTMSQERAMRHTIERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLM+GGGMYETGAGGSAPKHV QL+EEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLLEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FEDIGIKT NERAK+LGKTLDAAIG LL+N+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGACFEDIGIKTDNERAKVLGKTLDAAIGTLLENNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQEL A++DD +L +HFA+LAD L ++E+ IV EL QGE VDIGGYY Sbjct 661 GSQFYLALYWAQEL-AKSDDDELRKHFAALADSLAEHEETIVSELAAAQGEAVDIGGYYQ 719 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 PD++ TTA+MRPSKTFN AL A G Sbjct 720 PDTEKTTAIMRPSKTFNEALAASTG 744 >gi|226364172|ref|YP_002781954.1| isocitrate dehydrogenase [Rhodococcus opacus B4] gi|226242661|dbj|BAH53009.1| isocitrate dehydrogenase [Rhodococcus opacus B4] Length=746 Score = 1306 bits (3381), Expect = 0.0, Method: Compositional matrix adjust. Identities = 621/745 (84%), Positives = 679/745 (92%), Gaps = 1/745 (0%) Query 1 MSAEQP-TIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLT 59 MSA +P TIIYTLTDEAPLLATYAFLPIVR FA AGI+I++SDISVA+RILAEFP+ LT Sbjct 1 MSAHKPPTIIYTLTDEAPLLATYAFLPIVRTFAGAAGIEIDSSDISVASRILAEFPENLT 60 Query 60 EEQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTD 119 EEQRVPDNLAELGRLTQLP+TNIIKLPNISASVPQL+AAIKELQ KGY +PD+P DPK+D Sbjct 61 EEQRVPDNLAELGRLTQLPETNIIKLPNISASVPQLLAAIKELQGKGYKIPDFPDDPKSD 120 Query 120 QEKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMR 179 +E+ I++RY + LGSAVNPVLR+GNSDRRAP+AVK+YARKHPHSM EWSMASR+HVAHMR Sbjct 121 EEREIRQRYGKILGSAVNPVLREGNSDRRAPRAVKQYARKHPHSMEEWSMASRSHVAHMR 180 Query 180 HGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYE 239 HGDFY EKSMTLDR R VRMEL+ K+G+TIVLKPEV L +GD++DSMFMSK AL DFYE Sbjct 181 HGDFYHSEKSMTLDRPRKVRMELVTKAGETIVLKPEVELGEGDIMDSMFMSKTALLDFYE 240 Query 240 EQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGL 299 EQM+DA +TGVMFSLHVKATMMKVSHPIVFGHAV+ FYKDAFAKHQ LFD+LGVNVNNGL Sbjct 241 EQMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKTFYKDAFAKHQALFDELGVNVNNGL 300 Query 300 SDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 359 DLY KIESLP++QR+EII+DLH CHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI Sbjct 301 GDLYDKIESLPSTQREEIIQDLHDCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 360 Query 360 RAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQA 419 R+GGKMYGADG+ KD KAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+A Sbjct 361 RSGGKMYGADGRPKDAKAVMPESTFARIYQEIINFCKTNGAFDPTTMGTVPNVGLMAQKA 420 Query 420 EEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTR 479 EEYGSHDKTFEIPE+G AN VDV TGEVLLT++VE+GDIWRMC VKDAPIRDWVKLAVTR Sbjct 421 EEYGSHDKTFEIPEEGDANFVDVETGEVLLTQHVESGDIWRMCTVKDAPIRDWVKLAVTR 480 Query 480 ARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGL 539 AR SGMPVLFWLDPYRPHENELIKKV+ YL+DHDTEGLDIQIMSQVRSMRYT ERL+RG+ Sbjct 481 ARNSGMPVLFWLDPYRPHENELIKKVELYLQDHDTEGLDIQIMSQVRSMRYTLERLIRGM 540 Query 540 DTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEE 599 DTIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEE Sbjct 541 DTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEE 600 Query 600 NHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDN 659 NHLRWDSLGEFLAL E++G+KT NERAK+L KTLDAA GKLLD +KSPSRKTGELDN Sbjct 601 NHLRWDSLGEFLALAVSLEELGVKTDNERAKILAKTLDAATGKLLDENKSPSRKTGELDN 660 Query 660 RGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYY 719 RGSQFYLA YWAQELAAQ+DD++LAE FA+L L +NED IVREL EVQG VDIGGYY Sbjct 661 RGSQFYLARYWAQELAAQSDDKELAERFAALTKALDENEDTIVRELIEVQGSQVDIGGYY 720 Query 720 APDSDMTTAVMRPSKTFNAALEAVQ 744 D + T AVMRPS T N LEAVQ Sbjct 721 KLDGEKTAAVMRPSATLNTTLEAVQ 745 >gi|262202444|ref|YP_003273652.1| isocitrate dehydrogenase, NADP-dependent [Gordonia bronchialis DSM 43247] gi|262085791|gb|ACY21759.1| isocitrate dehydrogenase, NADP-dependent [Gordonia bronchialis DSM 43247] Length=745 Score = 1306 bits (3380), Expect = 0.0, Method: Compositional matrix adjust. Identities = 611/744 (83%), Positives = 680/744 (92%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+A+QPTIIYTLTDEAP+LAT+AFLP++RAFA+ A I +E SDISVAAR+LAEF DYLTE Sbjct 1 MNAKQPTIIYTLTDEAPMLATHAFLPVIRAFADAADINVETSDISVAARVLAEFDDYLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNL ELGRLTQ PDTNIIKLPNISASVPQLVA IKELQDKGY +PD+P +PKTD+ Sbjct 61 EQRVPDNLGELGRLTQNPDTNIIKLPNISASVPQLVATIKELQDKGYKIPDFPGNPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E I++RY +CLGSAVNPVLR+GNSDRRAP+AVKEYARKHPHSMG+WSMASRTHVAHM H Sbjct 121 ESQIRDRYTKCLGSAVNPVLREGNSDRRAPRAVKEYARKHPHSMGKWSMASRTHVAHMTH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS T+ R VRM+L G+TIVLKP+V L DGDVIDSMFMS+KAL +FYEE Sbjct 181 GDFYHGEKSTTVSGDREVRMQLTTADGETIVLKPKVSLTDGDVIDSMFMSRKALIEFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMM+VSHPIVFGHAV++FYKDAFAKH ELFD+LGVNVNNGLS Sbjct 241 QMQDAYETGVMFSLHVKATMMRVSHPIVFGHAVKVFYKDAFAKHGELFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIESLP+++R+EII+DLH+CHEHRPELAMVDSARGI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIESLPSAKREEIIDDLHKCHEHRPELAMVDSARGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+LKDTKAVNPESTFSRIYQE+INFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 361 AGGKMYGADGRLKDTKAVNPESTFSRIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+P+DGVA+IVD ATGEVLLT+NVE GDIWR+CIVKDAPI+DWVKLAVTRA Sbjct 421 EYGSHDKTFEVPKDGVADIVDNATGEVLLTQNVEEGDIWRLCIVKDAPIQDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPV+FWLDPYRPHENELI KV YLKDHDT+GLDIQIMSQVR++RYT ERL+RG+D Sbjct 481 RDSGMPVVFWLDPYRPHENELIAKVHKYLKDHDTDGLDIQIMSQVRAIRYTMERLIRGMD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHVKQL+EEN Sbjct 541 TISATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVKQLLEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+G K N +A++L KTLDAA GKLL+NDK PSRK GELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDLGKKQDNPKAQILAKTLDAATGKLLENDKGPSRKVGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWA+ELAAQTDD L +HFA LA+ L NED IV EL VQGEPVDIGGYYA Sbjct 661 GSQFYLALYWAKELAAQTDDADLQKHFAPLAEALEANEDAIVAELNGVQGEPVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PD+++ VMRPS+TFN ALE VQ Sbjct 721 PDNELLAKVMRPSETFNKALEDVQ 744 >gi|194292372|ref|YP_002008279.1| isocitrate dehydrogenase [nadp] (oxalosuccinate decarboxylase) (idh) [Cupriavidus taiwanensis LMG 19424] gi|193226276|emb|CAQ72225.1| Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) [Cupriavidus taiwanensis LMG 19424] Length=745 Score = 1305 bits (3377), Expect = 0.0, Method: Compositional matrix adjust. Identities = 615/743 (83%), Positives = 673/743 (91%), Gaps = 0/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI++ F +PAGI + SDISVA RIL EFPD+LTE Sbjct 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISVAGRILGEFPDFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELG+LTQLPDTNIIKLPNISASV QLV+AI+ELQ KGY VPDYP DPKTD+ Sbjct 61 EQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK YARKHPHSMGEWSMASRTHVAHM+H Sbjct 121 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMGEWSMASRTHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL+ KSGKTIVLKP+V L DG++IDSMFMSKKALC FYEE Sbjct 181 GDFYHGEKSMTLDRARDVKMELITKSGKTIVLKPKVSLQDGEIIDSMFMSKKALCAFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q +DA +TGVM SLHVKATMMKVSHPIVFGHAV+IFYK+AFAKH LFD+LGVNVNNGL Sbjct 241 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +LY KIESLP+S+R+EII DLH CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 NLYEKIESLPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 361 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEI EDGVANIVD+ATGEVLLT+NVE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIAEDGVANIVDLATGEVLLTQNVEQGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHE ELIKKV+TYLKDHDT GLDIQIMSQVR+MRYT ER++RGLD Sbjct 481 RNSGMPAVFWLDPYRPHEAELIKKVETYLKDHDTSGLDIQIMSQVRAMRYTLERVIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGN RAK+L KTLDAA GKLLDN+KSPS KTGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQ+DD +LA FA LA LT NE IV EL VQG+PVDIGGYY Sbjct 661 GSQFYLAMYWAQELAAQSDDAELAAKFAPLARTLTDNEQKIVGELAAVQGQPVDIGGYYQ 720 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 PD+ +A MRPS+T NAAL +V Sbjct 721 PDAAKLSAAMRPSQTLNAALASV 743 >gi|118465799|ref|YP_884223.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium 104] gi|118167086|gb|ABK67983.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium 104] Length=754 Score = 1292 bits (3343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 616/740 (84%), Positives = 670/740 (91%), Gaps = 0/740 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA+ PTIIYTLTDEAPLLATYA LP+V+ FA AGI ++ SDIS+AARILAEFPD+LTE Sbjct 1 MSAKPPTIIYTLTDEAPLLATYALLPVVQTFAAAAGINVKTSDISLAARILAEFPDHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 +QRVP+NLAEL LTQLPDTNIIKLPN+SASVPQL+AAIKELQ KG+ +P+YP DPKTD+ Sbjct 61 DQRVPNNLAELAELTQLPDTNIIKLPNVSASVPQLLAAIKELQAKGFDLPNYPGDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK I +RYARCLGSAVNPVLR+GNSDRRAPK VK+YARKHPHSMGEWSMASRTHVA M+H Sbjct 121 EKEITQRYARCLGSAVNPVLREGNSDRRAPKPVKQYARKHPHSMGEWSMASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR V+MEL K GKTIVLKP+V L DGDVIDSMFMSKKALC+FYE Sbjct 181 GDFYHGEKSMTLDRARGVKMELKTKGGKTIVLKPKVSLRDGDVIDSMFMSKKALCEFYEA 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV+IFYKDAFAKHQELFD+LGVNVNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKIFYKDAFAKHQELFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE+LPAS DEI+ DLH CHEHRPELAMVDSA+GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIETLPASLHDEIVRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKMYGADG+ KDTKAV+PESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMAQQAE Sbjct 361 LGGKMYGADGRTKDTKAVSPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVDV TGEVLLT++VE GDIWRM IV+D PIRDWVKLAV RA Sbjct 421 EYGSHDKTFEIPEDGVANIVDVDTGEVLLTQDVETGDIWRMPIVRDDPIRDWVKLAVDRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPV+FWLD RPHENEL KKV TYL D DTEGLDIQ MSQ R+MR+T ER +RG D Sbjct 481 RNSGMPVVFWLDQERPHENELRKKVNTYLADQDTEGLDIQTMSQERAMRHTIERAMRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGE+LALGA FED GIKTGN+RA +L K+LDAA GKLLDN+KSPSRKTGELDNR Sbjct 601 HLRWDSLGEYLALGACFEDTGIKTGNKRATILAKSLDAATGKLLDNNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQ DD++L +HFA+LAD L +ED I+ EL + QGE VDIGGYY Sbjct 661 GSQFYLALYWAQELAAQHDDEELRKHFAALADELRNHEDTILAELAKAQGESVDIGGYYR 720 Query 721 PDSDMTTAVMRPSKTFNAAL 740 PD + TAVMRPSKT N AL Sbjct 721 PDDEKLTAVMRPSKTLNDAL 740 >gi|120404190|ref|YP_954019.1| isocitrate dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119957008|gb|ABM14013.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium vanbaalenii PYR-1] Length=746 Score = 1291 bits (3342), Expect = 0.0, Method: Compositional matrix adjust. Identities = 616/743 (83%), Positives = 674/743 (91%), Gaps = 1/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQP+IIYTLTDEAPLLATYAFLP+VR FA AGI +++SDISVAARILAEF D LT+ Sbjct 1 MSAEQPSIIYTLTDEAPLLATYAFLPVVRTFASAAGIDVKSSDISVAARILAEFSDRLTD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+VPDNLAELG LTQ PDTNIIKLPNISASVPQL+AAIKEL+ KGY +PDYP DPKTD+ Sbjct 61 EQKVPDNLAELGALTQEPDTNIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKA+KERYA+ LGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWS ASRTHVA M+H Sbjct 121 EKAVKERYAKVLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELL-AKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYE 239 GDFY GEKSMTLD+ R V+M L + G +VLKPEV L+ GDVIDSM+MSKKAL DFYE Sbjct 181 GDFYHGEKSMTLDKDRKVKMVLEPSGGGPALVLKPEVALEKGDVIDSMYMSKKALIDFYE 240 Query 240 EQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGL 299 EQ++DA++TGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQ+LFD+LGVNVNNGL Sbjct 241 EQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGL 300 Query 300 SDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 359 SDLYSKIE LPASQR+EIIEDLHRCHEHRPELAMVDSA+GISNFHSPSDVIVDASMPAMI Sbjct 301 SDLYSKIEVLPASQREEIIEDLHRCHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMI 360 Query 360 RAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQA 419 R GGKMYGADG+ KDTKAVNPESTFSR+YQE+INFCKTNGQFDP TMGTVPNVGLMA +A Sbjct 361 RLGGKMYGADGRTKDTKAVNPESTFSRMYQEVINFCKTNGQFDPRTMGTVPNVGLMAMKA 420 Query 420 EEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTR 479 EEYGSHDKTFEIPEDGVANIVD+ TGEVLLT+NVE GDIWRM +VKDA IRDWVKLAVTR Sbjct 421 EEYGSHDKTFEIPEDGVANIVDIDTGEVLLTQNVEEGDIWRMPVVKDAAIRDWVKLAVTR 480 Query 480 ARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGL 539 AR+SGMP +FWLD RPHENEL +KVK YLK+ DT+GLDI I+ QV +MRYT ER++RG Sbjct 481 ARLSGMPAVFWLDDERPHENELREKVKAYLKEEDTDGLDITILPQVWAMRYTLERVIRGQ 540 Query 540 DTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEE 599 DTIA TGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QLVEE Sbjct 541 DTIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLVEE 600 Query 600 NHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDN 659 NHLRWDSLGEFLALGA FED+G K GN++A+LLGKTLD+AIGKLLDNDK PSR+TGELDN Sbjct 601 NHLRWDSLGEFLALGASFEDMGAKFGNKKAELLGKTLDSAIGKLLDNDKGPSRRTGELDN 660 Query 660 RGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYY 719 RGSQFYLAMYWAQELA QTDD+ LAEHFA LA L +NE IV EL QG+PVDIGGYY Sbjct 661 RGSQFYLAMYWAQELAEQTDDKALAEHFAPLAKTLAENESTIVDELNAAQGKPVDIGGYY 720 Query 720 APDSDMTTAVMRPSKTFNAALEA 742 PD + TTAVMRPS TFN+ALEA Sbjct 721 YPDQEKTTAVMRPSATFNSALEA 743 >gi|126433838|ref|YP_001069529.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium sp. JLS] gi|126233638|gb|ABN97038.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium sp. JLS] Length=745 Score = 1290 bits (3338), Expect = 0.0, Method: Compositional matrix adjust. Identities = 617/742 (84%), Positives = 668/742 (91%), Gaps = 0/742 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATY FLPI+R FA AGI +E SDISVAARIL EF D L E Sbjct 1 MSAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 +QRVPDNLA+LG LTQ P TNIIKLPNISASVPQL+AAIKEL+ KGY +PDYP DPKTD+ Sbjct 61 DQRVPDNLAKLGELTQDPATNIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK + RY + LGSAVNPVLRQGNSDRRAPKAVKEYA+KHPHSMGEWSMASRTHVA MRH Sbjct 121 EKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKHPHSMGEWSMASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMT+DR R V+M L KSG+TIVLKPEV LD+GD+IDSMFMSKKALC+FYE Sbjct 181 GDFYHGEKSMTIDRDRKVKMVLETKSGETIVLKPEVKLDEGDIIDSMFMSKKALCEFYEA 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQ+LFD+LGVNVNNG+S Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGMS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE+LPASQR+EII D+H CHE RPELAMVDSARGI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIEALPASQREEIINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKMYGADG+ KDTKAVNPESTFSR+YQE+IN+CKTNGQFDPTTMGTVPNVGLMAQ+AE Sbjct 361 LGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWCKTNGQFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANIVD+ T EVLLT+NVE GDIWRM IVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM +FWLD RPHE EL KKVK YLKDHDTEGL IQIM QV +MRYT ER+ RG D Sbjct 481 RASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERVTRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIA TGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QL+EEN Sbjct 541 TIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLIEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA FED+G KT N+RA LLGKT+DAAIGKLLDNDK PSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKTMDAAIGKLLDNDKGPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA QT+D++LAEHFA LA+ L KNE+ IV+EL QG+ VDIGGYY Sbjct 661 GSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDIGGYYY 720 Query 721 PDSDMTTAVMRPSKTFNAALEA 742 PDS+ TTAVMRPSKT N LE+ Sbjct 721 PDSEKTTAVMRPSKTLNETLES 742 >gi|116695867|ref|YP_841443.1| isocitrate dehydrogenase [NADP] [Ralstonia eutropha H16] gi|113530366|emb|CAJ96713.1| isocitrate dehydrogenase [NADP] [Ralstonia eutropha H16] Length=745 Score = 1286 bits (3327), Expect = 0.0, Method: Compositional matrix adjust. Identities = 604/743 (82%), Positives = 671/743 (91%), Gaps = 0/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI++ F +PAGI + SDISVA RIL EFP++LTE Sbjct 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISVAGRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELG+LTQLPDTNIIKLPNISASV QLV+AI+ELQ KGY VPDYP DPK D+ Sbjct 61 AQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKNDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK +ARKHPHSMGEWSMASRTHVAHM+H Sbjct 121 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNFARKHPHSMGEWSMASRTHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL+ KSGKTIVLKP+V L DG++IDSMFMSKKALCDFYEE Sbjct 181 GDFYHGEKSMTLDRARDVKMELVTKSGKTIVLKPKVSLLDGEIIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q +DA +TGVM SLHVKATMMKVSHPIVFGHAV+IFYK+AFAKH LFD+LGVNVNNGL Sbjct 241 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +LY KIE+LP+S+R+EII DLH CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 NLYEKIEALPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 361 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEI EDGVANIVD+ATGEVLLT++VE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIAEDGVANIVDLATGEVLLTQDVEQGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHE ELIKKV+TYLKD+DT GLDIQIMSQVR+MRYT ER++RGLD Sbjct 481 RNSGMPAVFWLDPYRPHEAELIKKVETYLKDYDTNGLDIQIMSQVRAMRYTLERVIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGN +AK+L +TLDAA GKLLDN+KSPS KTG+LDNR Sbjct 601 HLRWDSLGEFLALAVSLEDVGIKTGNAKAKILARTLDAATGKLLDNNKSPSPKTGQLDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA Q++D +LA FA LA LT NE IV EL VQG+PVDIGGYY Sbjct 661 GSQFYLAMYWAQELAGQSEDAELAAKFAPLARTLTDNEQKIVGELGAVQGQPVDIGGYYM 720 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 P++D +A MRPS+T NAAL V Sbjct 721 PEADKLSAAMRPSQTLNAALSTV 743 >gi|339323186|ref|YP_004682080.1| hypothetical protein CNE_2c18920 [Cupriavidus necator N-1] gi|338169794|gb|AEI80848.1| isocitrate dehydrogenase [NADP] [Cupriavidus necator N-1] Length=757 Score = 1284 bits (3323), Expect = 0.0, Method: Compositional matrix adjust. Identities = 605/743 (82%), Positives = 670/743 (91%), Gaps = 0/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI++ F +PAGI + SDISVA RIL EFP++LTE Sbjct 13 MSNQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISVAGRILGEFPEFLTE 72 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELG+LTQLPDTNIIKLPNISASV QLV+AI+ELQ KGY VPDYP DPKTD+ Sbjct 73 AQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKTDE 132 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK +ARKHPHSMGEWSMASRTHVAHM+H Sbjct 133 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNFARKHPHSMGEWSMASRTHVAHMKH 192 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLD+AR+V+MEL+ KSGKTIVLKP+V L DG++IDSMFMSKKALCDFYEE Sbjct 193 GDFYHGEKSMTLDKARDVKMELVTKSGKTIVLKPKVSLLDGEIIDSMFMSKKALCDFYEE 252 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q +DA +TGVM SLHVKATMMKVSHPIVFGHAV+IFYK+AFAKH LFD+LGVNVNNGL Sbjct 253 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 312 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +LY KIE+LP+S+R+EII DLH CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 313 NLYEKIEALPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 372 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 373 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 432 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEI EDGVANIVD+ATGEVLLT++VE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 433 EYGSHDKTFEIAEDGVANIVDLATGEVLLTQDVEQGDIWRMCQVKDAPIRDWVKLAVTRA 492 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHE ELIKKV+ YLK +DT GLDIQIMSQVR+MRYT ER++RGLD Sbjct 493 RNSGMPAVFWLDPYRPHEAELIKKVEAYLKGYDTTGLDIQIMSQVRAMRYTLERVIRGLD 552 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 553 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 612 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGN RAK+L KTLDAA GKLLDN+KSPS KTG+LDNR Sbjct 613 HLRWDSLGEFLALAVSLEDVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGQLDNR 672 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA Q+DD +LA FA LA LT NE IV EL VQG+PVDIGGYY Sbjct 673 GSQFYLAMYWAQELAVQSDDAELATKFAPLAKTLTDNEQKIVGELGAVQGKPVDIGGYYM 732 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 P++D +A MRPS+T NAAL V Sbjct 733 PEADKLSAAMRPSQTLNAALSTV 755 >gi|333991827|ref|YP_004524441.1| isocitrate dehydrogenase [Mycobacterium sp. JDM601] gi|333487795|gb|AEF37187.1| isocitrate dehydrogenase [Mycobacterium sp. JDM601] Length=744 Score = 1281 bits (3316), Expect = 0.0, Method: Compositional matrix adjust. Identities = 608/740 (83%), Positives = 673/740 (91%), Gaps = 0/740 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M A+QPTIIYTLTDEAPLLATY+FLPIV+AF EPAGI +++SDIS+AARILAEFPD LTE Sbjct 1 MCADQPTIIYTLTDEAPLLATYSFLPIVQAFTEPAGIDVKSSDISLAARILAEFPDVLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVP+NLAELGRLT+LPDT IIKLPNISASVPQLVAAIKELQ KG+A+PDYPADPKTD Sbjct 61 EQRVPNNLAELGRLTELPDTTIIKLPNISASVPQLVAAIKELQGKGFALPDYPADPKTDA 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E+ +RYA+CLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWS ASRTHVA MRH Sbjct 121 ERQTHDRYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL K GKTIVLK +V L DG +IDSMFMS +AL +FYE+ Sbjct 181 GDFYHGEKSMTLDRARDVKMELKTKGGKTIVLKEKVALSDGMIIDSMFMSVRALREFYEQ 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 +M+DA +TGVMFSLHVKATMMKVSHPIVFGHA+++FYKDAFAKHQ+LFDDLGVNVNNGL Sbjct 241 EMEDARKTGVMFSLHVKATMMKVSHPIVFGHAIKVFYKDAFAKHQKLFDDLGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY KIE+LPASQR+EIIED+H CHE PELAMVDSA GI+NFHSPSDVIVDASMPAMIR Sbjct 301 DLYDKIETLPASQREEIIEDMHACHEQGPELAMVDSANGITNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAVNPESTF+RIYQE+INFCKT+GQFDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMYGADGRTKDTKAVNPESTFARIYQELINFCKTHGQFDPATMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+PE G+A+IVD+ TGEVLLT+NVEAGDIWR+C V DA IRDWVKLAV RA Sbjct 421 EYGSHDKTFEVPEAGIADIVDLDTGEVLLTQNVEAGDIWRLCTVTDAAIRDWVKLAVERA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 RISGM V+FWLD RPHE EL KKVK YL DHDTEGL+IQIM QV +MRYT ERL+RG D Sbjct 481 RISGMTVVFWLDTERPHEAELRKKVKAYLADHDTEGLEIQIMPQVWAMRYTLERLIRGQD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA F+D+G KTGN AK+LG+TLD AIG+LL ++KSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALGASFDDMGAKTGNRGAKILGQTLDTAIGRLLADNKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQF+LA YWAQELAAQT+D LAEHFA++A+ L KN+DVI+ ELT VQG+ VDIGGYYA Sbjct 661 GSQFFLAKYWAQELAAQTEDAALAEHFAAVANGLEKNQDVILDELTVVQGKAVDIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAAL 740 PD D+T AVMRPS T NA + Sbjct 721 PDHDLTAAVMRPSPTLNAVI 740 >gi|108798180|ref|YP_638377.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium sp. MCS] gi|119867276|ref|YP_937228.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium sp. KMS] gi|108768599|gb|ABG07321.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium sp. MCS] gi|119693365|gb|ABL90438.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium sp. KMS] Length=750 Score = 1278 bits (3308), Expect = 0.0, Method: Compositional matrix adjust. Identities = 616/747 (83%), Positives = 667/747 (90%), Gaps = 5/747 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQPTIIYTLTDEAPLLATY FLPI+R FA AGI +E SDISVAARIL EF D L E Sbjct 1 MSAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 +QRVPDNLA+LG LTQ P TNIIKLPNISASVPQL+AAIKEL+ KGY +PDYP DPKTD+ Sbjct 61 DQRVPDNLAKLGELTQDPATNIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK + RY + LGSAVNPVLRQGNSDRRAPKAVKEYA+KHPHSMGEWSMASRTHVA MRH Sbjct 121 EKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKHPHSMGEWSMASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRM--ELLAKSG---KTIVLKPEVPLDDGDVIDSMFMSKKALC 235 GDFY GEKSMT+DR R V+M E K G +TIVLKPEV LD+GD+IDSMFMSKKALC Sbjct 181 GDFYHGEKSMTIDRDRKVKMVLETTPKDGEPARTIVLKPEVKLDEGDIIDSMFMSKKALC 240 Query 236 DFYEEQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNV 295 +FYE QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQ+LFD+LGVNV Sbjct 241 EFYEAQMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNV 300 Query 296 NNGLSDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASM 355 NNG+SDLYSKIE+LPASQR+EII D+H CHE RPELAMVDSARGI+NFHSPSDVIVDASM Sbjct 301 NNGMSDLYSKIEALPASQREEIINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASM 360 Query 356 PAMIRAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLM 415 PAMIR GGKMYGADG+ KDTKAVNPESTFSR+YQE+IN+CKTNGQFDPTTMGTVPNVGLM Sbjct 361 PAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWCKTNGQFDPTTMGTVPNVGLM 420 Query 416 AQQAEEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKL 475 AQ+AEEYGSHDKTFEIPEDGVANIVD+ T EVLLT+NVE GDIWRM IVKDAPIRDWVKL Sbjct 421 AQKAEEYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKL 480 Query 476 AVTRARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERL 535 AVTRAR SGM +FWLD RPHE EL KKVK YLKDHDTEGL IQIM QV +MRYT ER+ Sbjct 481 AVTRARASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERV 540 Query 536 VRGLDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQ 595 RG DTIA TGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV Q Sbjct 541 TRGQDTIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQ 600 Query 596 LVEENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTG 655 L+EENHLRWDSLGEFLALGA FED+G KT N+RA LLGKT+DAAIGKLLDNDK PSRKTG Sbjct 601 LIEENHLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKTMDAAIGKLLDNDKGPSRKTG 660 Query 656 ELDNRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDI 715 ELDNRGSQFYLAMYWAQELA QT+D++LAEHFA LA+ L KNE+ IV+EL QG+ VDI Sbjct 661 ELDNRGSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDI 720 Query 716 GGYYAPDSDMTTAVMRPSKTFNAALEA 742 GGYY PDS+ TTAVMRPSKT N LE+ Sbjct 721 GGYYYPDSEKTTAVMRPSKTLNETLES 747 >gi|118467432|ref|YP_886031.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium smegmatis str. MC2 155] gi|118168719|gb|ABK69615.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium smegmatis str. MC2 155] Length=743 Score = 1276 bits (3301), Expect = 0.0, Method: Compositional matrix adjust. Identities = 609/743 (82%), Positives = 668/743 (90%), Gaps = 0/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA+QPTIIYTLTDEAPLLATYAFLP+VR FAE AGI ++ SDISVAARILAEF D+LTE Sbjct 1 MSAQQPTIIYTLTDEAPLLATYAFLPVVRKFAEAAGIDVKTSDISVAARILAEFGDHLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNL ELG LTQ P NIIKLPNISASVPQL+AAIKELQ KGY VPDYPA+PKTD Sbjct 61 EQRVPDNLGELGALTQDPSANIIKLPNISASVPQLLAAIKELQGKGYNVPDYPANPKTDD 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK IK+RYA+ LGSAVNPVLR+GNSDRRAPKAVKEYARKHPHSMGEWS ASRTHVA M+ Sbjct 121 EKKIKDRYAKILGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKT 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDR R V+M L KSG+ IVLKPEV LD GD+IDSM+MSKKAL FYEE Sbjct 181 GDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALIAFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q++DA++TGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAFAKH++LFD+LGVNVNNGLS Sbjct 241 QIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKLFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY KIE+LPASQR+EIIEDLH+CHEHRPELAMVDSA+GISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYDKIEALPASQREEIIEDLHKCHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKMYGADG+ KDTKAVNPESTFSR+YQE+INFCKT+GQFDPTTMGTVPNVGLMAQ+AE Sbjct 361 LGGKMYGADGRTKDTKAVNPESTFSRMYQEMINFCKTHGQFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVA+IVD+ TGEVLLT+NVE GDIWRM IVKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVADIVDIDTGEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R+SGMPV+FWLD RPHE EL KKVK YLKDHDTEGL IQIM QV +MRYT ER+VRG D Sbjct 481 RLSGMPVVFWLDTERPHEVELRKKVKEYLKDHDTEGLKIQIMPQVWAMRYTLERVVRGKD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHV QLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLALGA ED+G KTGNE+AK+L K LD A GKLL+ +KSPSR+TGELDNR Sbjct 601 HLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYL+++WAQ LA QT+D +LAE F LA L + E+ IV EL VQG+ VDIGGYY Sbjct 661 GSQFYLSLFWAQALAEQTEDAELAERFKPLAKALAEQEEAIVSELNSVQGKTVDIGGYYY 720 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 PD + T+ VMRPSKTFN LE+V Sbjct 721 PDPEKTSEVMRPSKTFNTTLESV 743 >gi|295675933|ref|YP_003604457.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia sp. CCGE1002] gi|295435776|gb|ADG14946.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia sp. CCGE1002] Length=746 Score = 1271 bits (3288), Expect = 0.0, Method: Compositional matrix adjust. Identities = 599/744 (81%), Positives = 662/744 (89%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ +QPTIIYTLTDEAPLLAT AFLPI+R F PAGI++E SDISVA RIL EFP++LTE Sbjct 1 MTTQQPTIIYTLTDEAPLLATAAFLPIIRTFTRPAGIEVETSDISVAGRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELGRLT LPDTNIIKLPNISASVPQL +AIKELQ KGY VPDYP DPKTD Sbjct 61 AQRVPDNLAELGRLTSLPDTNIIKLPNISASVPQLTSAIKELQAKGYKVPDYPEDPKTDA 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK YARKHPHSM EWSMASRTHVA MRH Sbjct 121 EKAIRQRYSKCLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMTEWSMASRTHVATMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL+ K+GKTIVLKP+V L+DG++IDSMFMSKKAL FYE+ Sbjct 181 GDFYHGEKSMTLDRARDVKMELVTKNGKTIVLKPKVALEDGEIIDSMFMSKKALLAFYED 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TG+M SLHVKATMMK+SHPIVFGHAV++FYKDAFAKH +LF++LGVNVNNGL Sbjct 241 QMEDARKTGMMLSLHVKATMMKISHPIVFGHAVKVFYKDAFAKHGKLFEELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +LY KIE+LP SQR+E+I DLH CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 NLYEKIEALPESQREEVIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGAFDPVTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+PEDG A IVD+A+GEVLLT+NVE GDIWRMC VKDA IRDWVKLAVTR Sbjct 421 EYGSHDKTFEVPEDGEARIVDLASGEVLLTQNVEQGDIWRMCEVKDAAIRDWVKLAVTRV 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R S P +FWLDPYRPHE ELIKKV+ YLKD+DT GLDIQIMSQVR+MRYT ER+VRGLD Sbjct 481 RNSRTPAVFWLDPYRPHEAELIKKVEAYLKDYDTTGLDIQIMSQVRAMRYTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIKTGN RAK+L KTLD A GKLLDN++SPS KTGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEELGIKTGNNRAKILAKTLDTATGKLLDNNRSPSPKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQTDD LA FA LA LT NE VIV EL VQG P DIGGYY Sbjct 661 GSQFYLAMYWAQELAAQTDDAALAAQFAPLATQLTANEQVIVAELASVQGAPADIGGYYK 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PD + VMRPS+TFN AL+AV+ Sbjct 721 PDFNKLEEVMRPSRTFNEALKAVR 744 >gi|209516114|ref|ZP_03264973.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia sp. H160] gi|209503398|gb|EEA03395.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia sp. H160] Length=746 Score = 1269 bits (3284), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/744 (81%), Positives = 661/744 (89%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ +QPTIIYTLTDEAPLLAT AFLPI+R F PAGI++E SDISVA RIL EFP++LTE Sbjct 1 MTTQQPTIIYTLTDEAPLLATAAFLPIIRTFTAPAGIEVETSDISVAGRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELGRLT LPDTNIIKLPNISASVPQL +AIKELQ KGY VPDYP DPKTD Sbjct 61 AQRVPDNLAELGRLTLLPDTNIIKLPNISASVPQLTSAIKELQAKGYKVPDYPEDPKTDA 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK YARKHPHSM EWSMASRTHVAHMRH Sbjct 121 EKAIRQRYSKCLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMAEWSMASRTHVAHMRH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLD AR+V+ME++ KSGKT+VLKP+V L DG++IDSMFMS+KAL FYEE Sbjct 181 GDFYHGEKSMTLDHARDVKMEIVTKSGKTLVLKPKVALLDGEIIDSMFMSRKALLAFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVM SLHVKATMMK+SHPIVFGHAV++FYKDAFAKH +LFD+LGVNVNNGL Sbjct 241 QMEDARKTGVMLSLHVKATMMKISHPIVFGHAVKVFYKDAFAKHGKLFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +L+ K+E+LP SQR+E+I DLH CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 NLFEKLETLPESQREEVIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTKAV PESTF+RIYQE+INFCKTNG FDP TMGTVPNVGLMAQQAE Sbjct 361 LGGKMWGADGRPKDTKAVIPESTFARIYQEMINFCKTNGAFDPVTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+ EDG A IVD+ATGEVLLT+NVE GDIWRMC VKDA IRDWVKLAVTR Sbjct 421 EYGSHDKTFEVQEDGEARIVDLATGEVLLTQNVEQGDIWRMCQVKDAAIRDWVKLAVTRV 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SG P +FWLDPYRPHE ELIKKV+TYLKD+DT+GLDIQIMSQVR+MRYT ER+VRGLD Sbjct 481 RNSGTPAVFWLDPYRPHEAELIKKVETYLKDYDTKGLDIQIMSQVRAMRYTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIKTGN +AK+L KTLD A GKLLDN++SPS KTGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEELGIKTGNNKAKILAKTLDTATGKLLDNNRSPSPKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAM+WAQELAAQTDD LA FA LA LT NE VIV EL VQG P DIGGYY Sbjct 661 GSQFYLAMFWAQELAAQTDDAALAAQFAPLAAQLTANEKVIVAELASVQGAPADIGGYYK 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PD + VMRPS TFN AL+AV+ Sbjct 721 PDFNKLAEVMRPSHTFNEALKAVR 744 >gi|169630765|ref|YP_001704414.1| isocitrate dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169242732|emb|CAM63760.1| Probable isocitrate dehydrogenase [Mycobacterium abscessus] Length=745 Score = 1268 bits (3282), Expect = 0.0, Method: Compositional matrix adjust. Identities = 604/744 (82%), Positives = 664/744 (90%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA+QPTIIYTLTDEAPLLATY+FLPI+RAFA PAGI ++ SDISVAARIL+EF +YL E Sbjct 1 MSAQQPTIIYTLTDEAPLLATYSFLPIIRAFAGPAGIDVQTSDISVAARILSEFSEYLPE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 +QRVPDNLAELGRLTQLP+TNIIKLPNISASVPQL+AAIKELQ KGY +P+YP DPK ++ Sbjct 61 DQRVPDNLAELGRLTQLPETNIIKLPNISASVPQLLAAIKELQGKGYKLPEYPGDPKNEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E IK RY +CLGSAVNP+LR+GNSDRRAPKAVKEYARKHPHSMGEWS ASRTHVA M+ Sbjct 121 ETEIKARYTKCLGSAVNPILREGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKE 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS+TLDR R V+M L KSG T+VLKPEV L GD+IDSMFMSKKALCDFYEE Sbjct 181 GDFYHGEKSLTLDRDRTVKMVLTTKSGDTVVLKPEVKLGKGDIIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q++DA++TGVM SLHVKATMM+VSHPIVFGHAV+IFYKDAF KHQ+LFD+LGVNVNNGLS Sbjct 241 QIEDAYKTGVMLSLHVKATMMRVSHPIVFGHAVKIFYKDAFEKHQKLFDELGVNVNNGLS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLYSKIE+LPASQ +EII DLH CHEHRPELAMVDSA+GISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYSKIEALPASQHEEIIRDLHACHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGKLKDTKAVNPESTFSRIYQE+INF KT+GQFDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEMINFVKTHGQFDPRTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEI E GVA+IVD+ TGEVLLT+NVE GDIWRM +V DA I+DWVKLAVTR Sbjct 421 EYGSHDKTFEIAEAGVADIVDIDTGEVLLTQNVEEGDIWRMPVVTDAAIQDWVKLAVTRG 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGM V+FWLD RPHE EL KKVK YL+DHDTEGL IQ++ QV +MRYT ERL+RG D Sbjct 481 RESGMNVVFWLDTERPHEVELRKKVKEYLQDHDTEGLKIQVVPQVWAMRYTLERLIRGKD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHV QLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVSQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGN RAK+L TLDAA GKLL+NDKSPSRK GELDNR Sbjct 601 HLRWDSLGEFLALAVSLEDLGIKTGNARAKILATTLDAATGKLLENDKSPSRKAGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWA ELAAQT+D +LAE FA LA L +NED IV EL VQG P DIGGYYA Sbjct 661 GSQFYLALYWAAELAAQTEDVELAELFAPLAKQLVENEDQIVAELAAVQGSPADIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PD + T AVMRPS+TFNAAL +V+ Sbjct 721 PDPEKTNAVMRPSQTFNAALASVE 744 >gi|94312661|ref|YP_585870.1| isocitrate dehydrogenase [Cupriavidus metallidurans CH34] gi|93356513|gb|ABF10601.1| isocitrate dehydrogenase, NADP-dependent [Cupriavidus metallidurans CH34] Length=747 Score = 1266 bits (3277), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/747 (81%), Positives = 666/747 (90%), Gaps = 2/747 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI+R FA PAG+ + SDISVA RIL EFP++LTE Sbjct 1 MSNQQPTIIYTLTDEAPLLATSAFLPIIRTFAGPAGVNVVTSDISVAGRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELG+LTQ PDTNIIKLPNISASV QLV+AIKELQ KGY +PD+P DPKT++ Sbjct 61 AQRVPDNLAELGKLTQDPDTNIIKLPNISASVFQLVSAIKELQSKGYKIPDFPEDPKTEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK YARKHPHSMGEWSMASRTHVAHM+H Sbjct 121 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMGEWSMASRTHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS+TL+ AR VRMELL KSGKTIVLKP+V L DG+VIDSMFMSKKAL DFYE+ Sbjct 181 GDFYHGEKSITLNGAREVRMELLTKSGKTIVLKPKVALLDGEVIDSMFMSKKALLDFYED 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVM SLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQ+LFD+LGVNVNNGL Sbjct 241 QMEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY+KIE+LP S+R+E+I D+H CHEHRPE+AMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 DLYTKIETLPESKREEVIRDMHACHEHRPEMAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTK + PESTF+RIYQEIINFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct 361 IGGKMWGADGRTKDTKCLIPESTFARIYQEIINFCKTNGAFDPVTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVL--LTENVEAGDIWRMCIVKDAPIRDWVKLAVT 478 EYGSHDKTFEIPEDG A IVD ATGEVL LT+ VEAGDIWRMC VKDAPIRDWVKLAVT Sbjct 421 EYGSHDKTFEIPEDGEARIVDNATGEVLTALTQQVEAGDIWRMCQVKDAPIRDWVKLAVT 480 Query 479 RARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRG 538 RAR SGMP +FWLDPYRPHE ELIKKV+TYLKD+DT GLDIQIMSQVR+MRYT ER++RG Sbjct 481 RARNSGMPAVFWLDPYRPHEAELIKKVETYLKDYDTNGLDIQIMSQVRAMRYTLERVIRG 540 Query 539 LDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVE 598 LDTI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QLVE Sbjct 541 LDTISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVAQLVE 600 Query 599 ENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELD 658 ENHLRWDSLGEFLAL E++GIK+GNERAK+L TLDAA GKLLDN KSPS KTG+LD Sbjct 601 ENHLRWDSLGEFLALAVSLEELGIKSGNERAKILATTLDAATGKLLDNAKSPSPKTGQLD 660 Query 659 NRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGY 718 NRGSQFYLAMYWAQELAAQ D LA+ FA LA LT NE I+ EL VQG+PVDIGGY Sbjct 661 NRGSQFYLAMYWAQELAAQKGDADLAKIFAPLAKTLTDNESTIIGELGAVQGKPVDIGGY 720 Query 719 YAPDSDMTTAVMRPSKTFNAALEAVQG 745 Y PD+ M AVMRPS+T N+AL AV+ Sbjct 721 YMPDAAMLEAVMRPSQTLNSALAAVKA 747 >gi|21615534|emb|CAD32551.1| isocitrate dehydrogenase isozyme 2 [Cupriavidus necator] Length=745 Score = 1266 bits (3276), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/743 (81%), Positives = 665/743 (90%), Gaps = 0/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI++ F +PAGI + SDIS+A RIL EFP++LTE Sbjct 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISMAGRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELG+LTQLPDTNIIKLPNISASV QLV+AI+ELQ KGY VPDYP DPK D+ Sbjct 61 AQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKNDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSD RAP AVK +ARKHPHSMGEWSMASRTHVAHM+H Sbjct 121 EKAIQKRYSKCLGSAVNPVLREGNSDPRAPAAVKNFARKHPHSMGEWSMASRTHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 DFY GEKSMTLDRAR+V+MEL+ KSGKTIVLKP+V L DG++IDSMFMSKKALCDFYEE Sbjct 181 RDFYHGEKSMTLDRARDVKMELVTKSGKTIVLKPKVSLLDGEIIDSMFMSKKALCDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q +DA +TGVM SLHVKATMMKVSHPIVFGHAV+IFYK+AFAKH LFD+LGVNVNNGL Sbjct 241 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +LY KIE+LP+S+R+EII DLH CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 NLYEKIEALPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 361 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEI EDGV NIVD+ATGEVLLT++VE GDIWRM VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIAEDGVVNIVDLATGEVLLTQDVEQGDIWRMLQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHE ELIKKV+TYL D+DT GLDIQIMSQVR+MRYT ER++RGLD Sbjct 481 RNSGMPAVFWLDPYRPHEAELIKKVETYLIDYDTNGLDIQIMSQVRAMRYTLERVIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVE+N Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEDN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+GIKTGN +AK+L +TLDAA GKLLDN+KSPS KTG+LDNR Sbjct 601 HLRWDSLGEFLALAVSLEDVGIKTGNGKAKILARTLDAATGKLLDNNKSPSPKTGQLDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELA Q +D +LA FA LA LT NE IV EL VQG+PVDIGGYY Sbjct 661 GSQFYLAMYWAQELAGQLEDAELAAKFAPLARTLTDNEQKIVGELGAVQGQPVDIGGYYM 720 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 P++D +A MRPS+T NAAL V Sbjct 721 PEADKLSAAMRPSQTLNAALSTV 743 >gi|186474237|ref|YP_001861579.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia phymatum STM815] gi|184196569|gb|ACC74533.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia phymatum STM815] Length=747 Score = 1264 bits (3272), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/745 (81%), Positives = 664/745 (90%), Gaps = 2/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI+R F PAG+ +E SDISVA+RIL EFP++LTE Sbjct 1 MSNKQPTIIYTLTDEAPLLATSAFLPIIRTFTSPAGVNVETSDISVASRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELGRLTQ PDTNIIKLPNISASV QLV+AIKELQ KG+ VPDYP DPK ++ Sbjct 61 EQRVPDNLAELGRLTQDPDTNIIKLPNISASVFQLVSAIKELQSKGFKVPDYPEDPKNEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++CLGSAVNPVLR+GNSDRRAP AVK YA+KHPHSM EWSMASRTHVAHM+H Sbjct 121 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNYAKKHPHSMAEWSMASRTHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS+T D+AR VRMEL+ K G+TIVLKP+V L +G+++DSMFMSKKAL +FYE+ Sbjct 181 GDFYHGEKSITNDKAREVRMELVTKRGETIVLKPKVSLQEGEIVDSMFMSKKALVEFYED 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVM SLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQ+LFD+LGVNVNNGL Sbjct 241 QMEDAHKTGVMLSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY+KIE+LP SQR+E+I D+H CHEHRP LAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 DLYTKIEALPESQREEVIRDMHACHEHRPALAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADG+ DTK + PESTF+RIYQEIINFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGRPADTKCLIPESTFARIYQEIINFCKTNGAFDPRTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVL--LTENVEAGDIWRMCIVKDAPIRDWVKLAVT 478 EYGSHDKTFEI EDG A IVD ATGEVL LT+ VE GDIWRMC+VKDAPIRDWVKLAVT Sbjct 421 EYGSHDKTFEIKEDGEARIVDNATGEVLTALTQPVEQGDIWRMCLVKDAPIRDWVKLAVT 480 Query 479 RARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRG 538 RAR SG P +FWLDPYRPHENELIKKV+TYLKDHDT GLDIQIMSQVR+MRYT ER++RG Sbjct 481 RARNSGTPAVFWLDPYRPHENELIKKVQTYLKDHDTNGLDIQIMSQVRAMRYTLERVIRG 540 Query 539 LDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVE 598 LDTI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVE Sbjct 541 LDTISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVE 600 Query 599 ENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELD 658 ENHLRWDSLGEFLAL E++GIKTGN +AK+L KTLDAA GKLLDN++SPS KTG LD Sbjct 601 ENHLRWDSLGEFLALAVSLEELGIKTGNNKAKVLAKTLDAATGKLLDNNRSPSPKTGALD 660 Query 659 NRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGY 718 NRGSQFYLAMYWAQELAAQTDD +LA F LA VLT NE IV ELT+VQG+ VDIGGY Sbjct 661 NRGSQFYLAMYWAQELAAQTDDAELAAKFGPLAKVLTDNEATIVGELTDVQGKEVDIGGY 720 Query 719 YAPDSDMTTAVMRPSKTFNAALEAV 743 Y PD AVMRPSKT NAAL AV Sbjct 721 YKPDFAKLEAVMRPSKTLNAALAAV 745 >gi|343927284|ref|ZP_08766760.1| isocitrate dehydrogenase [Gordonia alkanivorans NBRC 16433] gi|343762777|dbj|GAA13686.1| isocitrate dehydrogenase [Gordonia alkanivorans NBRC 16433] Length=746 Score = 1264 bits (3271), Expect = 0.0, Method: Compositional matrix adjust. Identities = 595/744 (80%), Positives = 670/744 (91%), Gaps = 1/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS ++PTIIYTLTDEAP+LAT+AFLP+VR FA AGI++E SDISVAARILAEF D L E Sbjct 1 MSTQKPTIIYTLTDEAPMLATHAFLPVVRTFAGAAGIEVETSDISVAARILAEFSDLLPE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 +Q+V DNL ELG+LTQ PDTNIIKLPNISASVPQL+AAIKEL++KGY +P++P +PK ++ Sbjct 61 DQKVTDNLGELGKLTQDPDTNIIKLPNISASVPQLLAAIKELREKGYDLPEFPGNPKNEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E+AI++RY +CLGSAVNPVLR+GNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMR Sbjct 121 EQAIRDRYTKCLGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRE 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSG-KTIVLKPEVPLDDGDVIDSMFMSKKALCDFYE 239 GDFY GEKSMT++ R V+MEL+ G +T+VLKPEV + DGDVIDSMFMSKKAL FYE Sbjct 181 GDFYHGEKSMTVEGDRKVKMELIPDDGSETLVLKPEVDITDGDVIDSMFMSKKALIKFYE 240 Query 240 EQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGL 299 EQ++DA++TGVMFSLHVKATMM+VSHPIVFGHAV++FY+DAF KH ELFD+LGVNVNNGL Sbjct 241 EQIEDAYKTGVMFSLHVKATMMRVSHPIVFGHAVKVFYRDAFEKHGELFDELGVNVNNGL 300 Query 300 SDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 359 SDLYSKIESLP++QR+EII+DLH+CHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI Sbjct 301 SDLYSKIESLPSAQREEIIDDLHKCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMI 360 Query 360 RAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQA 419 RAGGKMYGADG+LKDTKAVNPESTFSRIYQE+INFCKTNGQFDPTTMGTVPNVGLMAQ+A Sbjct 361 RAGGKMYGADGRLKDTKAVNPESTFSRIYQEMINFCKTNGQFDPTTMGTVPNVGLMAQKA 420 Query 420 EEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTR 479 EEYGSHDKTFE+P G ANI D+ TGEVLLT+ VE GDIWR+CIVKDAPI+DW+KLAV R Sbjct 421 EEYGSHDKTFEVPVGGTANITDIETGEVLLTQTVEEGDIWRLCIVKDAPIQDWIKLAVNR 480 Query 480 ARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGL 539 R SGMPVLFWLDPYRPHENELIKKV YL +HDTEGLDIQIMSQVR+MRYT ER+VRGL Sbjct 481 CRDSGMPVLFWLDPYRPHENELIKKVHKYLPEHDTEGLDIQIMSQVRAMRYTLERVVRGL 540 Query 540 DTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEE 599 DTI+ATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHVKQL+EE Sbjct 541 DTISATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVKQLIEE 600 Query 600 NHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDN 659 NHLRWDSLGEFLAL ED+G K ++RA +L K LDAA GKLL+NDK PSRKTGELDN Sbjct 601 NHLRWDSLGEFLALAVSLEDMGKKFDDQRAVILAKALDAATGKLLENDKGPSRKTGELDN 660 Query 660 RGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYY 719 RGSQFYLA+YWAQELA QT+D +LA+ FA LA+ L NE+ IV EL VQG+ VDIGGYY Sbjct 661 RGSQFYLALYWAQELAGQTEDTELAKQFAPLAETLAANEEKIVEELNSVQGQQVDIGGYY 720 Query 720 APDSDMTTAVMRPSKTFNAALEAV 743 PD D T AVMRPSKTFN AL ++ Sbjct 721 YPDWDKTAAVMRPSKTFNEALASL 744 >gi|73538031|ref|YP_298398.1| isocitrate dehydrogenase NADP-dependent, monomeric type [Ralstonia eutropha JMP134] gi|72121368|gb|AAZ63554.1| Isocitrate dehydrogenase NADP-dependent, monomeric type [Ralstonia eutropha JMP134] Length=747 Score = 1262 bits (3266), Expect = 0.0, Method: Compositional matrix adjust. Identities = 595/747 (80%), Positives = 667/747 (90%), Gaps = 2/747 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MS +QPTIIYTLTDEAPLLAT AFLPI+R F +PA + + SDISVA RIL EFP++LTE Sbjct 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIRTFTKPADVNVVTSDISVAGRILGEFPEFLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRVPDNLAELG+LTQ PDTNIIKLPNISAS+ QL +AIKELQ KG+ VPDYP DPKTD+ Sbjct 61 EQRVPDNLAELGKLTQDPDTNIIKLPNISASLFQLTSAIKELQSKGFKVPDYPEDPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI++RY++ LGSAVNPVLR+GNSDRRAP AVK YARKHPHSMGEWSMASRTHVAHM+H Sbjct 121 EKAIQKRYSKVLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMGEWSMASRTHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKS+TLD+AR VRMEL KSGKTIVLKP+V L DG++IDSMFMSKKAL FYE+ Sbjct 181 GDFYHGEKSITLDKAREVRMELATKSGKTIVLKPKVSLQDGEIIDSMFMSKKALLAFYED 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVM SLHVKATMMKVSHPIVFGHAV++FYKDAFAKHQ+LFD+LGVNVNNGL Sbjct 241 QMEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGLV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY+KIE LP S+++E+I D+H CHEHRPELAMVDSA+GISN H+P+DVIVDASMPAMIR Sbjct 301 DLYTKIEQLPESKKEEVIRDMHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+ KDTK + PESTF+RIYQEIINFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct 361 IGGKMWGADGRTKDTKCLIPESTFARIYQEIINFCKTNGAFDPVTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVL--LTENVEAGDIWRMCIVKDAPIRDWVKLAVT 478 EYGSHDKTFEI EDG A IVD ATGEVL LT+ VE GDIWRMC VKDAPIRDWVKLAVT Sbjct 421 EYGSHDKTFEIAEDGEARIVDNATGEVLSALTQKVEQGDIWRMCQVKDAPIRDWVKLAVT 480 Query 479 RARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRG 538 RAR SGMP +FWLD YRPHE ELIKKV+TYLKD+DT+GLDIQIMSQVR+MRYT ER++RG Sbjct 481 RARNSGMPAVFWLDAYRPHEAELIKKVETYLKDYDTKGLDIQIMSQVRAMRYTLERVIRG 540 Query 539 LDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVE 598 LDTI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVE Sbjct 541 LDTISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVE 600 Query 599 ENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELD 658 ENHLRWDSLGEFLAL E++GIK+GN +AK+L KTLDAA GKLLDN KSPS KTG+LD Sbjct 601 ENHLRWDSLGEFLALAVSLEELGIKSGNAKAKVLAKTLDAATGKLLDNAKSPSPKTGQLD 660 Query 659 NRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGY 718 NRGSQFYLAMYWAQELAAQT+D LA FA LA LT NE IV EL++VQG+PVDIGGY Sbjct 661 NRGSQFYLAMYWAQELAAQTEDAALAATFAPLAKQLTDNEKTIVGELSDVQGKPVDIGGY 720 Query 719 YAPDSDMTTAVMRPSKTFNAALEAVQG 745 Y PD++ +A+MRPSKT NAAL++VQG Sbjct 721 YMPDAEKLSAIMRPSKTLNAALDSVQG 747 >gi|145224040|ref|YP_001134718.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium gilvum PYR-GCK] gi|315444376|ref|YP_004077255.1| isocitrate dehydrogenase, NADP-dependent, monomeric type [Mycobacterium sp. Spyr1] gi|145216526|gb|ABP45930.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium gilvum PYR-GCK] gi|315262679|gb|ADT99420.1| isocitrate dehydrogenase, NADP-dependent, monomeric type [Mycobacterium sp. Spyr1] Length=749 Score = 1260 bits (3261), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/748 (81%), Positives = 669/748 (90%), Gaps = 4/748 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSAEQP+IIYTLTDEAPLLATYAFLP+VR FA AGI ++++DISVAARILAEF D LT+ Sbjct 1 MSAEQPSIIYTLTDEAPLLATYAFLPVVRTFASAAGIDVKSTDISVAARILAEFSDRLTD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+V DNLAELG LTQLP+TNIIKLPNISASVPQL+AAIKEL+ KGY +PD+ +PK D+ Sbjct 61 EQKVTDNLAELGELTQLPETNIIKLPNISASVPQLLAAIKELKAKGYDLPDWVGEPKNDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E+ IKERY++ LGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWS ASRTHVA M+ Sbjct 121 EREIKERYSKVLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKT 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAK----SGKTIVLKPEVPLDDGDVIDSMFMSKKALCD 236 GDFY GEKSMT+D+ R V+M L + S +T VLKPEV LD+GDVIDSMFMSKKAL + Sbjct 181 GDFYHGEKSMTVDKDRKVKMVLTTERPDGSSETQVLKPEVSLDEGDVIDSMFMSKKALVE 240 Query 237 FYEEQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVN 296 FYEEQ++DA++TGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAF KH +LF +LGVNVN Sbjct 241 FYEEQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFEKHGKLFKELGVNVN 300 Query 297 NGLSDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMP 356 NG+SDLY KIESLPASQR+EIIED+HRCHEHRPELAMVDSARGI+NFHSPSDVIVDASMP Sbjct 301 NGMSDLYDKIESLPASQREEIIEDIHRCHEHRPELAMVDSARGITNFHSPSDVIVDASMP 360 Query 357 AMIRAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMA 416 AMIR GGKMYGADG+ KDTKAVNPESTFSRIYQEIINFCKT+GQFDPTTMGTVPNVGLMA Sbjct 361 AMIRLGGKMYGADGRTKDTKAVNPESTFSRIYQEIINFCKTHGQFDPTTMGTVPNVGLMA 420 Query 417 QQAEEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLA 476 +AEEYGSHDKTFEI EDGVA+IVD+ TGEVLL++NVE GDIWRM IVKDA IRDWVKLA Sbjct 421 MKAEEYGSHDKTFEITEDGVADIVDIETGEVLLSQNVEEGDIWRMPIVKDAAIRDWVKLA 480 Query 477 VTRARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLV 536 V RAR SGM +FWLD RPHENEL KKVKTYLK+ DT+GL+I I+ QV +MRYT ER++ Sbjct 481 VNRARQSGMTTVFWLDDERPHENELRKKVKTYLKEEDTDGLEITILPQVWAMRYTLERVI 540 Query 537 RGLDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQL 596 RG DTIA TGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV QL Sbjct 541 RGQDTIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVSQL 600 Query 597 VEENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGE 656 +EENHLRWDSLGEFLALGA FED+G K GN++A+LLGKTLD+AIGKLLDN+KSPSRK GE Sbjct 601 LEENHLRWDSLGEFLALGASFEDMGAKAGNKKAELLGKTLDSAIGKLLDNNKSPSRKAGE 660 Query 657 LDNRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIG 716 LDNRGSQFYLAMYWAQELA QTDD++LAEHFA LA L +NE+ IV E +VQGE VDIG Sbjct 661 LDNRGSQFYLAMYWAQELAEQTDDKELAEHFAPLAKTLAENEETIVEEFNKVQGESVDIG 720 Query 717 GYYAPDSDMTTAVMRPSKTFNAALEAVQ 744 GYY PD + TTAVMRPS TFN ALE+ + Sbjct 721 GYYYPDPEKTTAVMRPSSTFNEALESAR 748 >gi|296139966|ref|YP_003647209.1| isocitrate dehydrogenase, NADP-dependent [Tsukamurella paurometabola DSM 20162] gi|296028100|gb|ADG78870.1| isocitrate dehydrogenase, NADP-dependent [Tsukamurella paurometabola DSM 20162] Length=745 Score = 1250 bits (3235), Expect = 0.0, Method: Compositional matrix adjust. Identities = 595/744 (80%), Positives = 653/744 (88%), Gaps = 0/744 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA+Q TIIYTLTDEAPLLAT AFLPI+R FA PAGI ++ SDISVAARILA FP+ LTE Sbjct 1 MSAQQQTIIYTLTDEAPLLATAAFLPIIRTFAGPAGIDVQTSDISVAARILAAFPERLTE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQRV DNLA LG LTQ P NIIKLPNISASVPQL+AAI ELQ+KGY +PD P++PKTD+ Sbjct 61 EQRVTDNLAALGELTQDPSANIIKLPNISASVPQLLAAITELQEKGYDIPDLPSEPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E+ I RY+ LGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASR+HVAHM+H Sbjct 121 ERDIATRYSTILGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRSHVAHMKH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMT+D+ R+VRMEL+ G T VLKP V L GDV+DSMFMSKKAL DFYEE Sbjct 181 GDFYHGEKSMTIDKDRDVRMELVTADGNTNVLKPSVTLGPGDVMDSMFMSKKALLDFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QMQDA+ETGVMFSLHVKATMMKVSHPIVFGHAVR+FYK+AFAKH +LF++LGVNVNNGL Sbjct 241 QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVRVFYKEAFAKHHDLFEELGVNVNNGLG 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY KI +LPAS+ +EI++DLH CHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 301 DLYDKIATLPASKHEEIVKDLHACHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMYGADGRTKDTKAVMPESTFARIYQEIINFCKTNGAFDPRTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFE+P G ANIVD ATGEVLL++ VE GDIWRMC VKDAPIRDW+KLAV RA Sbjct 421 EYGSHDKTFEVPAAGTANIVDNATGEVLLSQEVEEGDIWRMCTVKDAPIRDWIKLAVNRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SG PVLFWLDPYRPHENELI KVK L+++DTEGLDIQIMSQVR+MRYT ER +RGLD Sbjct 481 RNSGTPVLFWLDPYRPHENELIAKVKAELENYDTEGLDIQIMSQVRAMRYTLERAMRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TIAATGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHVKQLVEEN Sbjct 541 TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E+ G+K N+ A L KTLDAA GKLL+N+K+PSR TGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEETGLKNDNKHAVTLAKTLDAATGKLLENNKAPSRSTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLA+YWAQELAAQTDD +LAE FA LA L ++E+ IV EL VQGEP DIGGYY Sbjct 661 GSQFYLALYWAQELAAQTDDPELAEKFAPLAAALAEHEETIVAELAAVQGEPADIGGYYY 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQ 744 PD + VMRPS TFNA L++VQ Sbjct 721 PDPEKMATVMRPSATFNADLDSVQ 744 >gi|56475870|ref|YP_157459.1| isocitrate dehydrogenase isozyme 2, monomeric type, NADP-specific [Aromatoleum aromaticum EbN1] gi|56311913|emb|CAI06558.1| Isocitrate dehydrogenase isozyme 2,monomeric type, NADP-specific [Aromatoleum aromaticum EbN1] Length=745 Score = 1246 bits (3223), Expect = 0.0, Method: Compositional matrix adjust. Identities = 590/740 (80%), Positives = 647/740 (88%), Gaps = 0/740 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ + PTIIYTLTDEAPLLATY+ LPI+ FA+PAGI I SDISVAARILAEF DYLT+ Sbjct 1 MTTKSPTIIYTLTDEAPLLATYSLLPIIETFAQPAGINIAKSDISVAARILAEFSDYLTD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 Q+VPDNLAELGRLTQ PDTNIIKLPNISA+V QL AI ELQ KGYA+P+YP PKTD+ Sbjct 61 AQKVPDNLAELGRLTQDPDTNIIKLPNISAAVQQLTTAIAELQQKGYAIPNYPETPKTDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK IK+RY + LGSAVNPVLR+GNSDRRAP AVK YARKHPHSMGEWSMASRTHVAHM+ Sbjct 121 EKIIKQRYGKALGSAVNPVLREGNSDRRAPAAVKRYARKHPHSMGEWSMASRTHVAHMKS 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+M+L+ SGKTIVLKP+V L DG++IDSMFMSK ALC FYEE Sbjct 181 GDFYHGEKSMTLDRARDVKMDLITNSGKTIVLKPKVALLDGEIIDSMFMSKNALCAFYEE 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 QM+DA +TGVMFSLHVKATMMKVSHPIVFGHAV+IFYK+AF KH +LFD+LGVNVNNG+S Sbjct 241 QMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKIFYKEAFEKHGKLFDELGVNVNNGMS 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 +LY KI LP S+RDEI+ DLH CHEHRPELAMVDSA+GI+N H+P+DVIVDASMPAMIR Sbjct 301 NLYEKIAPLPESKRDEIVRDLHACHEHRPELAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADGK KDTKAV PESTF+RIYQE+INFCKTNG FDP TMGTVPNVGLMAQQAE Sbjct 361 IGGKMWGADGKPKDTKAVMPESTFARIYQEMINFCKTNGNFDPRTMGTVPNVGLMAQQAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE G A IVD+ATGEVLL +NVE GDIWRMC KDA IRDWVKLAV RA Sbjct 421 EYGSHDKTFEIPEAGEARIVDIATGEVLLVQNVEEGDIWRMCQAKDAAIRDWVKLAVNRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP LFWLDPYRPHE ELIKKV+TYLKDHDT GLDIQIMSQVR+MRYT ER++RGLD Sbjct 481 RNSGMPTLFWLDPYRPHEAELIKKVETYLKDHDTTGLDIQIMSQVRAMRYTLERVIRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL A ED+GIKTGN++AKLL +TLD A GKLLDNDKSPSRKTGELDNR Sbjct 601 HLRWDSLGEFLALTASLEDMGIKTGNDKAKLLARTLDEATGKLLDNDKSPSRKTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GS FYLA+YWAQ LAAQ DD +L FA +A L +NE IV EL QG P DIGGYY Sbjct 661 GSHFYLALYWAQALAAQDDDAELKSRFAPMAKALAENEQKIVDELHAPQGRPADIGGYYL 720 Query 721 PDSDMTTAVMRPSKTFNAAL 740 PD T AVMRPS TFNA L Sbjct 721 PDPAKTRAVMRPSATFNAIL 740 >gi|338975141|ref|ZP_08630496.1| isocitrate dehydrogenase (NADP) [Bradyrhizobiaceae bacterium SG-6C] gi|338231740|gb|EGP06875.1| isocitrate dehydrogenase (NADP) [Bradyrhizobiaceae bacterium SG-6C] Length=796 Score = 1236 bits (3198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 586/743 (79%), Positives = 655/743 (89%), Gaps = 1/743 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 MSA PTIIYTLTDEAP LAT AFLPIVRAFA PAGI + SDISVAARIL EFP++LTE Sbjct 53 MSA-TPTIIYTLTDEAPALATAAFLPIVRAFAAPAGINVTTSDISVAARILGEFPEFLTE 111 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 QRVPDNLAELGRLT LP+TNIIKLPNISASV QL AAIKELQ KGY VPDYP +PKTD Sbjct 112 PQRVPDNLAELGRLTLLPETNIIKLPNISASVAQLKAAIKELQGKGYKVPDYPENPKTDD 171 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAI+ RYA+C+GSAVNPVLR+GNSDRRAP AVK YARK+PHSM EWS ASR+HV+HM Sbjct 172 EKAIRARYAKCIGSAVNPVLREGNSDRRAPLAVKNYARKNPHSMAEWSQASRSHVSHMHG 231 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRAR+V+MEL+ KSGKTI+LKP+V L D ++IDSMFMSKKAL +FYE+ Sbjct 232 GDFYHGEKSMTLDRARDVKMELITKSGKTILLKPKVSLQDREIIDSMFMSKKALLEFYEK 291 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 +++DA++TGVMFSLHVKATMMKVSHPIVFGH V+IFY+DAF KH ELF +LGVNVNNG+ Sbjct 292 EIEDAYKTGVMFSLHVKATMMKVSHPIVFGHCVKIFYRDAFEKHDELFRELGVNVNNGMV 351 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY+KI +LP S++DEI DLH CHEHRPELAMVDSA+GI+NFHSP+D+IVDASMPAMIR Sbjct 352 DLYNKIATLPQSKQDEIKRDLHACHEHRPELAMVDSAKGITNFHSPNDIIVDASMPAMIR 411 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKM+GADG+LKD KAV PESTF+RIYQE+INFCK +G FDP TMGTVPNVGLMAQQAE Sbjct 412 NGGKMWGADGRLKDVKAVMPESTFARIYQEMINFCKWHGNFDPKTMGTVPNVGLMAQQAE 471 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANI D+ATGEVLL+E+VE GDIWRMC KDA +RDWVKLAVTRA Sbjct 472 EYGSHDKTFEIPEDGVANITDLATGEVLLSEDVEQGDIWRMCQTKDAAVRDWVKLAVTRA 531 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMPVLFWLDPYRPHE +LI KVK YL +HDT GLDIQIMSQVR+MRYT ER++RG D Sbjct 532 RNSGMPVLFWLDPYRPHEAQLITKVKMYLHEHDTSGLDIQIMSQVRAMRYTLERVIRGQD 591 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ATGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVEEN Sbjct 592 TISATGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 651 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL ED+G+KT N +AKLL KTLDAA GKLLDN+KSPS +TGELDNR Sbjct 652 HLRWDSLGEFLALAVSLEDLGLKTNNPKAKLLAKTLDAATGKLLDNNKSPSPRTGELDNR 711 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWAQELAAQT+D +L F LA+VL +NE+ IV EL VQG+P DIGGYY Sbjct 712 GSQFYLAMYWAQELAAQTEDPELQAKFKGLAEVLAQNEEKIVAELAAVQGQPADIGGYYL 771 Query 721 PDSDMTTAVMRPSKTFNAALEAV 743 PD+ +VMRPSKT NAAL V Sbjct 772 PDAAKCASVMRPSKTLNAALAQV 794 >gi|326382779|ref|ZP_08204469.1| isocitrate dehydrogenase, NADP-dependent [Gordonia neofelifaecis NRRL B-59395] gi|326198369|gb|EGD55553.1| isocitrate dehydrogenase, NADP-dependent [Gordonia neofelifaecis NRRL B-59395] Length=744 Score = 1231 bits (3184), Expect = 0.0, Method: Compositional matrix adjust. Identities = 586/735 (80%), Positives = 647/735 (89%), Gaps = 1/735 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+++ TIIYTLTDEAP LAT AFLPI+R FAEPAGI ++ SDISVAARILA FPDYL++ Sbjct 1 MASKDQTIIYTLTDEAPRLATSAFLPIIRTFAEPAGIDVQTSDISVAARILAAFPDYLSD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+V DNLAELGRLTQLP+TNIIKLPNISASVPQL AAI ELQDKGYA+PDYP DPKT + Sbjct 61 EQKVSDNLAELGRLTQLPETNIIKLPNISASVPQLNAAIHELQDKGYAIPDYPQDPKTPE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 E+ I+ RY CLGSAVNPVLR+GNSDRRAPKAVKEYARK+PHSMG+WSMAS++HVAHM H Sbjct 121 EEEIRNRYGACLGSAVNPVLREGNSDRRAPKAVKEYARKNPHSMGKWSMASQSHVAHMTH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFYAGEKSM +D A + RME++ G+T V+K VPL+ GDVIDSMFMSKKAL +FYEE Sbjct 181 GDFYAGEKSMIMDHACDARMEVVTPDGETHVMK-TVPLEKGDVIDSMFMSKKALLEFYEE 239 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q+ DA ETGVMFSLHVKATMMKVSHPIVFGHAV++FYKDAFAKH +LFD+LGVNVNNGL Sbjct 240 QLNDAKETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHGDLFDELGVNVNNGLV 299 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DLY KI++LPAS+R+EI+EDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR Sbjct 300 DLYEKIDTLPASKREEIVEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 359 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 GGKMYGADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDPTTMGTVPNVGLMAQ+AE Sbjct 360 IGGKMYGADGRKKDTKAVMPESTFARIYQEIINFCKTNGAFDPTTMGTVPNVGLMAQKAE 419 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE GVANIVD +TGEVLL+++VE GDIWRMCIVKDAPIRDWVKLAVTR+ Sbjct 420 EYGSHDKTFEIPEGGVANIVDASTGEVLLSQDVEQGDIWRMCIVKDAPIRDWVKLAVTRS 479 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHEN LI VK YL+DHDTEGLDIQIMSQVR+MRYT ER +RGLD Sbjct 480 RASGMPAVFWLDPYRPHENNLITLVKKYLQDHDTEGLDIQIMSQVRAMRYTLERAMRGLD 539 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHVKQLVEEN Sbjct 540 TISVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVKQLVEEN 599 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL A ED+G K N +A +L TLDAA KLLDN KSPSRKTGELDNR Sbjct 600 HLRWDSLGEFLALAASLEDLGRKNDNPKASILATTLDAATSKLLDNRKSPSRKTGELDNR 659 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYLAMYWA+ELAAQTDD +LAE FA LA L +E IV E+ VQG VD+GGYY Sbjct 660 GSQFYLAMYWAEELAAQTDDAELAERFAPLAQRLAADEQKIVDEIAAVQGHSVDLGGYYL 719 Query 721 PDSDMTTAVMRPSKT 735 D + M PS T Sbjct 720 ADGEKLEQAMCPSAT 734 >gi|169632785|ref|YP_001706521.1| isocitrate dehydrogenase [Acinetobacter baumannii SDF] gi|184159009|ref|YP_001847348.1| monomeric isocitrate dehydrogenase [Acinetobacter baumannii ACICU] gi|239501105|ref|ZP_04660415.1| monomeric isocitrate dehydrogenase [Acinetobacter baumannii AB900] 12 more sequence titles Length=745 Score = 1225 bits (3169), Expect = 0.0, Method: Compositional matrix adjust. Identities = 573/745 (77%), Positives = 644/745 (87%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ E+ TIIYTLTDEAPLLATY+ LPI+ F +PAGI+I SDISVAAR+LAEF DYL+E Sbjct 1 MAGEKSTIIYTLTDEAPLLATYSLLPIIETFTKPAGIEIVKSDISVAARVLAEFADYLSE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+V DNLAELGRLTQ PDTNIIKLPNISASV QL A IKELQ KGYA+PDYP +P T++ Sbjct 61 EQKVSDNLAELGRLTQDPDTNIIKLPNISASVAQLTACIKELQSKGYAIPDYPENPATEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK IK RY +CLGSAVNPVLR+GNSDRRAP AVK YA+KHPHSM EW S+THV+HM Sbjct 121 EKTIKARYGKCLGSAVNPVLREGNSDRRAPAAVKNYAKKHPHSMSEWKQWSQTHVSHMEE 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDR RNV+MEL+ SGK+IVLKP+V L +G++IDSMFMSKKALCDFYE+ Sbjct 181 GDFYHGEKSMTLDRPRNVKMELITNSGKSIVLKPKVALQEGEIIDSMFMSKKALCDFYEK 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q+ D E G++FSLHVKATMMKVSHPIVFGH V+I+YK+AF KH +LFD+LG+NVNNG++ Sbjct 241 QLDDCREAGILFSLHVKATMMKVSHPIVFGHCVKIYYKEAFEKHGKLFDELGINVNNGMA 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 LY KIE+LP S R+EIIEDLH C EHRP LAMVDSA+GI+NFHSP+D+IVDASMPAMIR Sbjct 301 GLYEKIETLPTSLREEIIEDLHACQEHRPALAMVDSAKGITNFHSPNDIIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADGK D KAV PESTF+RIYQE+INFCK +G FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGKQYDAKAVMPESTFARIYQEMINFCKWHGNFDPKTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE G+ANI D+ TGEVLLT+NVE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEAGIANITDLDTGEVLLTQNVEEGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHENELIKKV+ YLKDHDT GLDIQIMSQVR+MRYT ER+VRGLD Sbjct 481 RNSGMPAIFWLDPYRPHENELIKKVQKYLKDHDTTGLDIQIMSQVRAMRYTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIK N RAKLL KTLD A GKLLDNDKSPSR+TGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEEMGIKENNARAKLLAKTLDEATGKLLDNDKSPSRRTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GS FYL++YWA+ LAAQ +D +L FA LA L +NE IV EL +VQG+P DIGGYYA Sbjct 661 GSHFYLSLYWAEALAAQNEDAELKAKFAPLAKALAENEQKIVAELAQVQGKPADIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 D +AVMRPS TFNAAL VQ Sbjct 721 VDPAKVSAVMRPSATFNAALSTVQA 745 >gi|119897437|ref|YP_932650.1| isocitrate dehydrogenase [Azoarcus sp. BH72] gi|119669850|emb|CAL93763.1| isocitrate dehydrogenase[NADP] [Azoarcus sp. BH72] Length=745 Score = 1225 bits (3169), Expect = 0.0, Method: Compositional matrix adjust. Identities = 571/745 (77%), Positives = 656/745 (89%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M ++QPTIIYT+TDEAP+LAT AFLP++R+F +PAGI+IE +DIS+A RILAEFPD+L++ Sbjct 1 MPSQQPTIIYTITDEAPMLATAAFLPVIRSFTKPAGIQIEEADISLAGRILAEFPDFLSD 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 Q+VP+ LAELG LT P+ NIIKLPNISASV QL AAIKELQ KGY +PD+P DPK D+ Sbjct 61 AQKVPNTLAELGALTLKPEANIIKLPNISASVAQLKAAIKELQGKGYKIPDFPEDPKNDE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EKAIK RY++CLGS+VNPVLR+GNSDRRAP AVK YA+KHPHSMG+W SRTHV+HM H Sbjct 121 EKAIKTRYSKCLGSSVNPVLREGNSDRRAPAAVKNYAKKHPHSMGDWKQWSRTHVSHMEH 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLD+AR+V+MELL KSGK IVLKP+V L DG+VIDSMFMSKKAL +FYE+ Sbjct 181 GDFYHGEKSMTLDKARDVKMELLTKSGKAIVLKPKVALLDGEVIDSMFMSKKALLEFYEQ 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q++D E G++FSLHVKATMMKVSHPIVFGH V+I+YK+AF KH +LFD+LG+NVNNG+ Sbjct 241 QLEDCREAGILFSLHVKATMMKVSHPIVFGHCVKIYYKEAFEKHGKLFDELGINVNNGMV 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 DL+ KI++LP S+RDEII DLH CHEHRPELAMVDSA+GI+NFHSP+DVIVDASMPAMIR Sbjct 301 DLFDKIKTLPESKRDEIIRDLHACHEHRPELAMVDSAKGITNFHSPNDVIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKMYGADGK D KAV PESTF+RIYQE+INFCK +G FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMYGADGKPYDCKAVMPESTFARIYQEMINFCKWHGNFDPRTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPEDGVANI D+ATGEVLL++NVEAGDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEDGVANITDLATGEVLLSQNVEAGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHENELIKKV+ YLKDHDT GL+I+IMSQVR+MR+T ER+VRGLD Sbjct 481 RNSGMPAVFWLDPYRPHENELIKKVEKYLKDHDTSGLEIRIMSQVRAMRFTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLM GGGMYETGAGGSAPKHV+QLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMNGGGMYETGAGGSAPKHVQQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIKTGN +AK+L KTLD A GKLLD DKSPSR+TGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEELGIKTGNAKAKVLAKTLDEATGKLLDLDKSPSRRTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GSQFYL++YWAQ LAAQTDD +LA F LA L +NE IV EL VQG+P +IGGYY Sbjct 661 GSQFYLSLYWAQALAAQTDDAELAAQFGPLAKTLAENEQKIVDELKAVQGKPAEIGGYYR 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 D + TAVMRPS TFNAA+ ++ G Sbjct 721 VDVEKCTAVMRPSATFNAAIASIAG 745 >gi|169795135|ref|YP_001712928.1| isocitrate dehydrogenase [Acinetobacter baumannii AYE] gi|213158202|ref|YP_002320253.1| isocitrate dehydrogenase, NADP-dependent [Acinetobacter baumannii AB0057] gi|215482682|ref|YP_002324878.1| isocitrate dehydrogenase, NADP-dependent [Acinetobacter baumannii AB307-0294] 10 more sequence titles Length=745 Score = 1224 bits (3168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 573/745 (77%), Positives = 643/745 (87%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ E+ TIIYTLTDEAPLLATY+ LPI+ F +PAGI+I SDISVAAR+LAEF DYL+E Sbjct 1 MAGEKSTIIYTLTDEAPLLATYSLLPIIETFTKPAGIEIVKSDISVAARVLAEFADYLSE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+V DNLAELGRLTQ PDTNIIKLPNISASV QL A IKELQ KGYA+PDYP +P T++ Sbjct 61 EQKVSDNLAELGRLTQDPDTNIIKLPNISASVAQLTACIKELQSKGYAIPDYPENPATEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK IK RY +CLGSAVNPVLR+GNSDRRAP AVK YA+KHPHSM EW S+THV+HM Sbjct 121 EKTIKARYGKCLGSAVNPVLREGNSDRRAPAAVKNYAKKHPHSMSEWKQWSQTHVSHMEE 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDR RNV+MEL+ SGK+IVLKP+V L +G++IDSMFMSKKALCDFYE+ Sbjct 181 GDFYHGEKSMTLDRPRNVKMELITNSGKSIVLKPKVALQEGEIIDSMFMSKKALCDFYEK 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q+ D E G++FSLHVKATMMKVSHPIVFGH V+I+YK+AF KH +LFD+LG+NVNNG++ Sbjct 241 QLDDCREAGILFSLHVKATMMKVSHPIVFGHCVKIYYKEAFEKHGKLFDELGINVNNGMA 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 LY KIE+LP S R+EIIEDLH C EHRP LAMVDSA+GI+NFHSP+D+IVDASMPAMIR Sbjct 301 GLYEKIETLPTSLREEIIEDLHACQEHRPALAMVDSAKGITNFHSPNDIIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADGK D KAV PESTF+RIYQE+INFCK +G FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGKQYDAKAVMPESTFARIYQEMINFCKWHGNFDPKTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE G+ANI D TGEVLLT+NVE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEAGIANITDFDTGEVLLTQNVEEGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHENELIKKV+ YLKDHDT GLDIQIMSQVR+MRYT ER+VRGLD Sbjct 481 RNSGMPAIFWLDPYRPHENELIKKVQKYLKDHDTTGLDIQIMSQVRAMRYTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIK N RAKLL KTLD A GKLLDNDKSPSR+TGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEEMGIKENNARAKLLAKTLDEATGKLLDNDKSPSRRTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GS FYL++YWA+ LAAQ +D +L FA LA L +NE IV EL +VQG+P DIGGYYA Sbjct 661 GSHFYLSLYWAEALAAQNEDAELKAKFAPLAKALAENEQKIVAELAQVQGKPADIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 D +AVMRPS TFNAAL VQ Sbjct 721 VDPAKVSAVMRPSATFNAALSTVQA 745 >gi|260556623|ref|ZP_05828841.1| monomeric isocitrate dehydrogenase [Acinetobacter baumannii ATCC 19606] gi|260409882|gb|EEX03182.1| monomeric isocitrate dehydrogenase [Acinetobacter baumannii ATCC 19606] Length=745 Score = 1224 bits (3166), Expect = 0.0, Method: Compositional matrix adjust. Identities = 572/745 (77%), Positives = 643/745 (87%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ E+ TIIYTLTDEAPLLATY+ LPI+ F +PAGI+I SDISVAAR+LAEF DYL+E Sbjct 1 MAGEKSTIIYTLTDEAPLLATYSLLPIIETFTKPAGIEIVKSDISVAARVLAEFADYLSE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+V DNLAELGRLTQ PDTNIIKLPNISASV QL A IKELQ KGYA+PDYP +P T++ Sbjct 61 EQKVSDNLAELGRLTQDPDTNIIKLPNISASVAQLTACIKELQSKGYAIPDYPENPATEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK IK RY +CLGSAVNPVLR+GNSDRRAP AVK YA+KHPHSM EW S+THV+HM Sbjct 121 EKTIKARYGKCLGSAVNPVLREGNSDRRAPAAVKNYAKKHPHSMSEWKQWSQTHVSHMEE 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDR RNV+MEL+ SGK+IVLKP+V L +G++IDSMFMSKKALCDFYE+ Sbjct 181 GDFYHGEKSMTLDRPRNVKMELITNSGKSIVLKPKVALQEGEIIDSMFMSKKALCDFYEK 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 Q+ D E G++FSLHVKATMMKVSHPIVFGH V+I+YK+AF KH +LFD+LG+NVNNG++ Sbjct 241 QLDDCREAGILFSLHVKATMMKVSHPIVFGHCVKIYYKEAFEKHGKLFDELGINVNNGMA 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 LY KIE+LP S R+EIIEDLH C EHRP LAMVDSA+GI+NFHSP+D+IVDASMPAMIR Sbjct 301 GLYEKIETLPTSLREEIIEDLHACQEHRPALAMVDSAKGITNFHSPNDIIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADGK D KAV PESTF+RIYQE+INFCK +G FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGKQYDAKAVMPESTFARIYQEMINFCKWHGNFDPKTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEIPE G+ANI D+ TGEVLLT+NVE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEIPEAGIANITDLDTGEVLLTQNVEEGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHENELIKKV+ YLKDHDT GLDIQIMSQVR+MRYT ER+VRGLD Sbjct 481 RNSGMPAIFWLDPYRPHENELIKKVQKYLKDHDTTGLDIQIMSQVRAMRYTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIK N R KLL KTLD A GKLLDNDKSPSR+TGELDNR Sbjct 601 HLRWDSLGEFLALAVSLEEMGIKENNARTKLLAKTLDEATGKLLDNDKSPSRRTGELDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GS FYL++YWA+ LAAQ +D +L FA LA L +NE IV EL +VQG+P DIGGYYA Sbjct 661 GSHFYLSLYWAEALAAQNEDAELKAKFAPLAKALAENEQKIVAELAQVQGKPADIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 D +AVMRPS TFNAAL VQ Sbjct 721 VDPAKVSAVMRPSATFNAALSTVQA 745 >gi|319950242|ref|ZP_08024169.1| isocitrate dehydrogenase, NADP-dependent [Dietzia cinnamea P4] gi|319436146|gb|EFV91339.1| isocitrate dehydrogenase, NADP-dependent [Dietzia cinnamea P4] Length=744 Score = 1222 bits (3162), Expect = 0.0, Method: Compositional matrix adjust. Identities = 584/738 (80%), Positives = 645/738 (88%), Gaps = 1/738 (0%) Query 8 IIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTEEQRVPDN 67 IIYTLTDEAP LAT AFLP++R FA PAGI +E SDISVAARILA FP+ LTEEQRVPDN Sbjct 8 IIYTLTDEAPRLATEAFLPVLRTFAAPAGIGVETSDISVAARILAAFPERLTEEQRVPDN 67 Query 68 LAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQEKAIKER 127 LAELGRLTQ PDTNIIKLPNISASVPQL AAI EL++KGY +PDYP DPKT +EK I ER Sbjct 68 LAELGRLTQEPDTNIIKLPNISASVPQLTAAIAELREKGYDLPDYPYDPKTPEEKEIAER 127 Query 128 YARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRHGDFYAGE 187 Y CLGSAVNPVLRQGNSDRRAPKAVKEYAR +PHSMG+WSMAS+THVAHM HGDFYAGE Sbjct 128 YGSCLGSAVNPVLRQGNSDRRAPKAVKEYARANPHSMGKWSMASQTHVAHMTHGDFYAGE 187 Query 188 KSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEEQMQDAFE 247 KS+ LDRA + RME++ G+T VLK VPL+ G+V+DSMFMSKKAL DFYEEQ+ DA E Sbjct 188 KSIILDRACDARMEIVTPDGETHVLK-TVPLEAGEVVDSMFMSKKALLDFYEEQLDDAKE 246 Query 248 TGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLSDLYSKIE 307 TGVMFSLHVKATMMKVSHPIVFGHAVR+FYKDAFAKH ELFD+LGVNVNNG+ DLY K+E Sbjct 247 TGVMFSLHVKATMMKVSHPIVFGHAVRVFYKDAFAKHGELFDELGVNVNNGMGDLYDKLE 306 Query 308 SLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIRAGGKMYG 367 SLP S+++E+IED+HRCHE RPELAMVDSARGI+NFHSPSDVIVDASMPAMIR GGKMYG Sbjct 307 SLPTSKKEEVIEDIHRCHESRPELAMVDSARGITNFHSPSDVIVDASMPAMIRIGGKMYG 366 Query 368 ADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGSHDK 427 ADG+ KDTKAV PESTF+RIYQEIINFCKTNG FDP TMGTVPNVGLMAQ+AEEYGSHDK Sbjct 367 ADGRKKDTKAVIPESTFARIYQEIINFCKTNGAFDPRTMGTVPNVGLMAQKAEEYGSHDK 426 Query 428 TFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISGMPV 487 TFE+ GVANIVD ATGEVLL++NVEAGDIWRMC VKDAPIRDWV+LAV RAR SGMP Sbjct 427 TFEVQHGGVANIVDAATGEVLLSQNVEAGDIWRMCTVKDAPIRDWVRLAVDRARASGMPA 486 Query 488 LFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAATGN 547 +FWLDPYRPHEN LI VK YL +HDTEGLDIQIMSQVR+MRYT ER RGLDTI+ TGN Sbjct 487 VFWLDPYRPHENNLITLVKKYLAEHDTEGLDIQIMSQVRAMRYTLERAWRGLDTISVTGN 546 Query 548 ILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDSL 607 ILRDYLTDLFPILELGTSAKMLS+VPLMAGGG+YETGAGGSAPKHV+QLVEENHLRWDSL Sbjct 547 ILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVQQLVEENHLRWDSL 606 Query 608 GEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQFYLA 667 GEFLALGA ED+G K N +A +L +TLD A GKLL+N KSPSR+TGELDNRGSQF+L+ Sbjct 607 GEFLALGASLEDVGRKYDNPKAAILARTLDTATGKLLENRKSPSRETGELDNRGSQFWLS 666 Query 668 MYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSDMTT 727 +YWAQELAAQ+DD LA HFA LA L +D I+ EL EVQG+PVD+GGYY P D Sbjct 667 LYWAQELAAQSDDPDLAAHFAPLAGKLDAEKDTILGELLEVQGKPVDLGGYYQPAIDKLK 726 Query 728 AVMRPSKTFNAALEAVQG 745 MRPS+TFNAAL ++ G Sbjct 727 EAMRPSETFNAALASISG 744 >gi|293609787|ref|ZP_06692089.1| isocitrate dehydrogenase [Acinetobacter sp. SH024] gi|292828239|gb|EFF86602.1| isocitrate dehydrogenase [Acinetobacter sp. SH024] Length=745 Score = 1221 bits (3159), Expect = 0.0, Method: Compositional matrix adjust. Identities = 570/745 (77%), Positives = 645/745 (87%), Gaps = 0/745 (0%) Query 1 MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE 60 M+ E+ TIIYTLTDEAPLLATY+ LPI+ F +PAGI+I SDISVAAR+LAEF DYL+E Sbjct 1 MAGEKSTIIYTLTDEAPLLATYSLLPIIETFTKPAGIEIIKSDISVAARVLAEFADYLSE 60 Query 61 EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ 120 EQ+V DNLAELGRLTQ PDTNIIKLPNISASV QL A IKELQ KGYA+PDYP +P T++ Sbjct 61 EQKVSDNLAELGRLTQDPDTNIIKLPNISASVAQLTACIKELQSKGYAIPDYPENPTTEE 120 Query 121 EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH 180 EK+IK RY +CLGSAVNPVLR+GNSDRRAP AVK YA+KHPHSM EW S+THV+HM Sbjct 121 EKSIKARYGKCLGSAVNPVLREGNSDRRAPAAVKNYAKKHPHSMSEWKQWSQTHVSHMEE 180 Query 181 GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE 240 GDFY GEKSMTLDRARNV+MEL+ SGK+IVLKP+V L +G++IDSMFMSKKALCDFYE+ Sbjct 181 GDFYHGEKSMTLDRARNVKMELITNSGKSIVLKPKVALQEGEIIDSMFMSKKALCDFYEK 240 Query 241 QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS 300 ++ D E G++FSLHVKATMMKVSHPIVFGH V+I+YK+AF KH +LFD+LG+NVNNG++ Sbjct 241 ELDDCKEAGILFSLHVKATMMKVSHPIVFGHCVKIYYKEAFEKHGKLFDELGINVNNGMA 300 Query 301 DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR 360 LY KIE+LP S R+EIIEDLH C EHRP LAMVDSA+GI+NFHSP+D+IVDASMPAMIR Sbjct 301 GLYEKIETLPTSLREEIIEDLHACQEHRPALAMVDSAKGITNFHSPNDIIVDASMPAMIR 360 Query 361 AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE 420 AGGKM+GADGK D KAV PESTF+RIYQE+INFCK +G FDP TMGTVPNVGLMAQ+AE Sbjct 361 AGGKMWGADGKQYDAKAVMPESTFARIYQEMINFCKWHGNFDPKTMGTVPNVGLMAQKAE 420 Query 421 EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA 480 EYGSHDKTFEI E G+ANI D+ TGEVLLT+NVE GDIWRMC VKDAPIRDWVKLAVTRA Sbjct 421 EYGSHDKTFEISEAGIANITDLDTGEVLLTQNVEEGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query 481 RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD 540 R SGMP +FWLDPYRPHENELIKKV+ YLKDHDT GLDIQIMSQVR+MRYT ER+VRGLD Sbjct 481 RNSGMPAIFWLDPYRPHENELIKKVQKYLKDHDTTGLDIQIMSQVRAMRYTLERVVRGLD 540 Query 541 TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 TI+ TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGMYETGAGGSAPKHV+QLVEEN Sbjct 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 600 Query 601 HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR 660 HLRWDSLGEFLAL E++GIK N RAKLL KTLD A GKLLDNDKSPSR+TGE+DNR Sbjct 601 HLRWDSLGEFLALAVSLEEMGIKENNARAKLLAKTLDEATGKLLDNDKSPSRRTGEIDNR 660 Query 661 GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA 720 GS FYL++YWA+ LAAQ +D +L FA LA L +NE+ IV EL +VQG+P DIGGYYA Sbjct 661 GSHFYLSLYWAEALAAQNEDAELKAKFAPLAKALAENEEKIVAELAQVQGKPADIGGYYA 720 Query 721 PDSDMTTAVMRPSKTFNAALEAVQG 745 D AVMRPS TFNAAL V+ Sbjct 721 IDPTKVNAVMRPSATFNAALATVEA 745 Lambda K H 0.317 0.134 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1782709545916 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40