BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0077c Length=276 Score E Sequences producing significant alignments: (Bits) Value gi|15607219|ref|NP_214591.1| oxidoreductase [Mycobacterium tuber... 556 1e-156 gi|15839456|ref|NP_334493.1| alpha/beta fold family hydrolase [M... 556 1e-156 gi|340625111|ref|YP_004743563.1| putative oxidoreductase [Mycoba... 554 5e-156 gi|339293145|gb|AEJ45256.1| alpha/beta fold family hydrolase [My... 505 3e-141 gi|296167206|ref|ZP_06849612.1| alpha/beta hydrolase fold family... 466 2e-129 gi|240168829|ref|ZP_04747488.1| putative oxidoreductase [Mycobac... 458 4e-127 gi|342862289|ref|ZP_08718930.1| hydrolase, alpha/beta hydrolase ... 458 5e-127 gi|254549009|ref|ZP_05139456.1| putative oxidoreductase [Mycobac... 454 8e-126 gi|118466115|ref|YP_884367.1| hydrolase, alpha/beta hydrolase fa... 447 6e-124 gi|41410390|ref|NP_963226.1| hypothetical protein MAP4292 [Mycob... 446 1e-123 gi|183980256|ref|YP_001848547.1| oxidoreductase [Mycobacterium m... 443 1e-122 gi|118619924|ref|YP_908256.1| oxidoreductase [Mycobacterium ulce... 439 2e-121 gi|254819453|ref|ZP_05224454.1| hydrolase, alpha/beta hydrolase ... 431 6e-119 gi|336459834|gb|EGO38747.1| putative hydrolase or acyltransferas... 305 5e-81 gi|284047131|ref|YP_003397471.1| alpha/beta hydrolase fold prote... 198 7e-49 gi|312199420|ref|YP_004019481.1| alpha/beta hydrolase fold prote... 195 7e-48 gi|256391200|ref|YP_003112764.1| alpha/beta hydrolase fold prote... 173 2e-41 gi|126438113|ref|YP_001073804.1| alpha/beta hydrolase fold prote... 173 2e-41 gi|108802132|ref|YP_642329.1| alpha/beta hydrolase fold protein ... 173 3e-41 gi|302529515|ref|ZP_07281857.1| conserved hypothetical protein [... 171 1e-40 gi|326329362|ref|ZP_08195687.1| hydrolase, alpha/beta hydrolase ... 167 1e-39 gi|300787011|ref|YP_003767302.1| alpha/beta hydrolase [Amycolato... 167 1e-39 gi|300787755|ref|YP_003768046.1| alpha/beta hydrolase [Amycolato... 167 2e-39 gi|118618372|ref|YP_906704.1| oxidoreductase [Mycobacterium ulce... 165 6e-39 gi|302545125|ref|ZP_07297467.1| alpha/beta hydrolase fold family... 164 2e-38 gi|298244041|ref|ZP_06967848.1| alpha/beta hydrolase fold protei... 163 3e-38 gi|337763434|emb|CCB72142.1| putative hydrolase [Streptomyces ca... 162 3e-38 gi|291452359|ref|ZP_06591749.1| oxidoreductase [Streptomyces alb... 162 4e-38 gi|183982780|ref|YP_001851071.1| oxidoreductase [Mycobacterium m... 162 7e-38 gi|297204577|ref|ZP_06921974.1| oxidoreductase [Streptomyces svi... 159 3e-37 gi|169627300|ref|YP_001700949.1| alpha/beta fold hydrolase [Myco... 158 8e-37 gi|291448612|ref|ZP_06588002.1| oxidoreductase [Streptomyces ros... 157 1e-36 gi|345002793|ref|YP_004805647.1| alpha/beta hydrolase fold prote... 155 5e-36 gi|284047111|ref|YP_003397451.1| alpha/beta hydrolase fold prote... 153 3e-35 gi|226364624|ref|YP_002782406.1| hydrolase [Rhodococcus opacus B... 152 5e-35 gi|239991610|ref|ZP_04712274.1| haloalkane dehalogenase [Strepto... 152 7e-35 gi|54023417|ref|YP_117659.1| putative hydrolase [Nocardia farcin... 151 1e-34 gi|54026900|ref|YP_121142.1| putative hydrolase [Nocardia farcin... 149 6e-34 gi|291301237|ref|YP_003512515.1| alpha/beta hydrolase fold prote... 147 1e-33 gi|254385252|ref|ZP_05000583.1| alpha/beta hydrolase [Streptomyc... 147 2e-33 gi|343925819|ref|ZP_08765334.1| putative hydrolase [Gordonia alk... 147 2e-33 gi|111022131|ref|YP_705103.1| haloalkane dehalogenase [Rhodococc... 147 2e-33 gi|326381618|ref|ZP_08203312.1| alpha/beta hydrolase fold protei... 146 4e-33 gi|343497499|ref|ZP_08735565.1| hydrolase/oxidase [Vibrio nigrip... 145 6e-33 gi|111221877|ref|YP_712671.1| putative oxidoreductase [Frankia a... 145 6e-33 gi|118466225|ref|YP_881063.1| alpha/beta hydrolase [Mycobacteriu... 145 9e-33 gi|302528323|ref|ZP_07280665.1| alpha/beta hydrolase fold protei... 144 1e-32 gi|297190088|ref|ZP_06907486.1| oxidoreductase [Streptomyces pri... 144 1e-32 gi|229820227|ref|YP_002881753.1| alpha/beta hydrolase fold prote... 144 2e-32 gi|118472544|ref|YP_890971.1| oxidoreductase [Mycobacterium smeg... 139 3e-31 >gi|15607219|ref|NP_214591.1| oxidoreductase [Mycobacterium tuberculosis H37Rv] gi|31791254|ref|NP_853747.1| oxidoreductase [Mycobacterium bovis AF2122/97] gi|121635988|ref|YP_976211.1| putative oxidoreductase [Mycobacterium bovis BCG str. Pasteur 1173P2] 44 more sequence titles Length=276 Score = 556 bits (1433), Expect = 1e-156, Method: Compositional matrix adjust. Identities = 276/276 (100%), Positives = 276/276 (100%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA Sbjct 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL Sbjct 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA Sbjct 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT Sbjct 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 >gi|15839456|ref|NP_334493.1| alpha/beta fold family hydrolase [Mycobacterium tuberculosis CDC1551] gi|253796994|ref|YP_003029995.1| oxidoreductase [Mycobacterium tuberculosis KZN 1435] gi|254233475|ref|ZP_04926801.1| hypothetical protein TBCG_00077 [Mycobacterium tuberculosis C] 29 more sequence titles Length=284 Score = 556 bits (1433), Expect = 1e-156, Method: Compositional matrix adjust. Identities = 276/276 (100%), Positives = 276/276 (100%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA Sbjct 9 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 68 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL Sbjct 69 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 128 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV Sbjct 129 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 188 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA Sbjct 189 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 248 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT Sbjct 249 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 284 >gi|340625111|ref|YP_004743563.1| putative oxidoreductase [Mycobacterium canettii CIPT 140010059] gi|340003301|emb|CCC42418.1| putative oxidoreductase [Mycobacterium canettii CIPT 140010059] Length=276 Score = 554 bits (1427), Expect = 5e-156, Method: Compositional matrix adjust. Identities = 275/276 (99%), Positives = 276/276 (100%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA Sbjct 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL Sbjct 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALE+GQRLAA Sbjct 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALEDGQRLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT Sbjct 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 >gi|339293145|gb|AEJ45256.1| alpha/beta fold family hydrolase [Mycobacterium tuberculosis CCDC5079] Length=252 Score = 505 bits (1301), Expect = 3e-141, Method: Compositional matrix adjust. Identities = 251/252 (99%), Positives = 252/252 (100%), Gaps = 0/252 (0%) Query 25 VFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVL 84 +FVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVL Sbjct 1 MFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVL 60 Query 85 AALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSA 144 AALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSA Sbjct 61 AALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSA 120 Query 145 TLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEV 204 TLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEV Sbjct 121 TLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEV 180 Query 205 TTAVAARLPEFDKPALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDR 264 TTAVAARLPEFDKPALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDR Sbjct 181 TTAVAARLPEFDKPALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDR 240 Query 265 LADQLSTVAVRT 276 LADQLSTVAVRT Sbjct 241 LADQLSTVAVRT 252 >gi|296167206|ref|ZP_06849612.1| alpha/beta hydrolase fold family hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897447|gb|EFG77047.1| alpha/beta hydrolase fold family hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=276 Score = 466 bits (1198), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 229/276 (83%), Positives = 245/276 (89%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPE+GRPVVFVHGYMMGGQLWR VSERLA RGLRCIAPTWPLGA Sbjct 1 MSTIDISAGTIHYEATGPESGRPVVFVHGYMMGGQLWRGVSERLADRGLRCIAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLR GAD+TI GVAG+VAD LAAL L+DVVLVGNDTGGVVTQLVAVH+P+RLGALVL Sbjct 61 HPEPLRRGADRTITGVAGMVADALAALGLEDVVLVGNDTGGVVTQLVAVHHPDRLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKS FR Q MR PAAR RA+ GL+H NID LT AWV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSKATFRGVAQAMRVPAARKRAFDGLTHRNIDDLTEAWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RP LS+PAIAEDLRQ +LSLRTEVT VAARLPEFDKP LIAWSADDVFF E+G RLAA Sbjct 181 RPGLSDPAIAEDLRQFTLSLRTEVTAGVAARLPEFDKPTLIAWSADDVFFEQEDGARLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP AR EVI+GARTFSM+D PDRLAD LS++AVRT Sbjct 241 TIPNARLEVIDGARTFSMIDQPDRLADLLSSIAVRT 276 >gi|240168829|ref|ZP_04747488.1| putative oxidoreductase [Mycobacterium kansasii ATCC 12478] Length=276 Score = 458 bits (1179), Expect = 4e-127, Method: Compositional matrix adjust. Identities = 234/276 (85%), Positives = 254/276 (93%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHY+ TGP GRPVVFVHGYMMGGQLWR+V+ERLAGRGLRC+APTWPLGA Sbjct 1 MSTIDISAGTIHYDVTGPANGRPVVFVHGYMMGGQLWRQVAERLAGRGLRCLAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLRPGADQ+I GVAGIVA+ LAAL+L+DVVLVGNDTGGVVTQLVAVH+ ER+GALVL Sbjct 61 HPEPLRPGADQSISGVAGIVAEFLAALDLQDVVLVGNDTGGVVTQLVAVHHRERVGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFE+FPPPILKPVILAAKS LFRAAIQ MRAPAAR RAY L++ +ID LT+AWV Sbjct 121 TSCDAFENFPPPILKPVILAAKSKPLFRAAIQTMRAPAARRRAYDDLAYADIDELTQAWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPALSNP +AEDLR SLSLRTEVTT VAARLPEFDKPALIAWSADD FFALE+G+RLAA Sbjct 181 RPALSNPRVAEDLRHFSLSLRTEVTTGVAARLPEFDKPALIAWSADDKFFALEDGERLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP ARFE+IEGARTFSMVD PDRLAD LSTVAVRT Sbjct 241 TIPNARFELIEGARTFSMVDQPDRLADLLSTVAVRT 276 >gi|342862289|ref|ZP_08718930.1| hydrolase, alpha/beta hydrolase family protein [Mycobacterium colombiense CECT 3035] gi|342130146|gb|EGT83474.1| hydrolase, alpha/beta hydrolase family protein [Mycobacterium colombiense CECT 3035] Length=276 Score = 458 bits (1178), Expect = 5e-127, Method: Compositional matrix adjust. Identities = 224/276 (82%), Positives = 245/276 (89%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPE GRPVVFVHGYMMGGQLWR++ ERLA RGLRCIAPTWPLGA Sbjct 1 MSTIDISAGTIHYEATGPEDGRPVVFVHGYMMGGQLWRQLGERLAARGLRCIAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLR GAD++I GVAG+VA+VLAAL+L+DVVLVGNDTGGVVTQLVAVH+ +RLGALVL Sbjct 61 HPEPLRRGADRSITGVAGMVAEVLAALDLRDVVLVGNDTGGVVTQLVAVHHRDRLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKS T FRA Q MR PA R RA+ GL+H NID LT AWV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSKTSFRAVAQAMRVPAVRKRAFDGLAHSNIDELTEAWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RP LS+PAIAEDLRQ +LS+RTEVTT VAARL +FDKP LIAWSADDVFF E+G RLAA Sbjct 181 RPGLSDPAIAEDLRQFTLSMRTEVTTTVAARLYDFDKPTLIAWSADDVFFEQEDGARLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP AR EVI GARTFSM+D PD+LAD LST+AVRT Sbjct 241 TIPNARLEVIAGARTFSMIDQPDQLADLLSTIAVRT 276 >gi|254549009|ref|ZP_05139456.1| putative oxidoreductase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=249 Score = 454 bits (1167), Expect = 8e-126, Method: Compositional matrix adjust. Identities = 224/225 (99%), Positives = 225/225 (100%), Gaps = 0/225 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA Sbjct 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL Sbjct 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSA 225 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWS+ Sbjct 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSS 225 >gi|118466115|ref|YP_884367.1| hydrolase, alpha/beta hydrolase family protein [Mycobacterium avium 104] gi|254777600|ref|ZP_05219116.1| hydrolase, alpha/beta hydrolase fold family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118167402|gb|ABK68299.1| hydrolase, alpha/beta hydrolase fold family protein [Mycobacterium avium 104] Length=276 Score = 447 bits (1151), Expect = 6e-124, Method: Compositional matrix adjust. Identities = 221/276 (81%), Positives = 244/276 (89%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGP GRPVVFVHGY+MGGQLWR+V +RLAGRGLRCIAPTWP+GA Sbjct 1 MSTIDISAGTIHYEATGPADGRPVVFVHGYLMGGQLWRQVGDRLAGRGLRCIAPTWPMGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLR GAD+TI GVA +VA++L+AL+L+DVVLVGNDTGGVV+QLVAVH+ ERLGALVL Sbjct 61 HPEPLRRGADRTITGVAAMVAELLSALDLEDVVLVGNDTGGVVSQLVAVHHRERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPP+L+PVILAAKS FRA Q MRAPA R RA+ GL+H NID LT WV Sbjct 121 TSCDAFEHFPPPVLRPVILAAKSKATFRAVAQAMRAPAVRKRAFDGLAHSNIDALTELWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPALS PA+AEDLR+ +LSLRTEVTTA AARL +FDKP LIAWSADDVFFA E+G RLAA Sbjct 181 RPALSLPAVAEDLRRFTLSLRTEVTTAAAARLYDFDKPTLIAWSADDVFFAQEDGARLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP AR EVI GARTFSMVD PDRLAD LSTVAVRT Sbjct 241 TIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT 276 >gi|41410390|ref|NP_963226.1| hypothetical protein MAP4292 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41399224|gb|AAS06842.1| hypothetical protein MAP_4292 [Mycobacterium avium subsp. paratuberculosis K-10] Length=276 Score = 446 bits (1148), Expect = 1e-123, Method: Compositional matrix adjust. Identities = 220/276 (80%), Positives = 243/276 (89%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGP GRPVVFVHGY+MGGQLWR+V +RLAGRGLRCIAPTWP+GA Sbjct 1 MSTIDISAGTIHYEATGPADGRPVVFVHGYLMGGQLWRQVGDRLAGRGLRCIAPTWPMGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLR GAD+TI GVA +VA++L+AL+L+DVVLVGNDTGGVV+QLVAVH+ ERLGALVL Sbjct 61 HPEPLRRGADRTITGVAAMVAELLSALDLEDVVLVGNDTGGVVSQLVAVHHRERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPP+L+PVILAAKS FRA Q MRAPA R RA+ GL+H NID LT WV Sbjct 121 TSCDAFEHFPPPVLRPVILAAKSKATFRAVAQAMRAPAVRKRAFDGLAHSNIDALTELWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPALS PA+AEDLR+ +LSLRTEVTTA A RL +FDKP LIAWSADDVFFA E+G RLAA Sbjct 181 RPALSLPAVAEDLRRFTLSLRTEVTTAAATRLYDFDKPTLIAWSADDVFFAQEDGARLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP AR EVI GARTFSMVD PDRLAD LSTVAVRT Sbjct 241 TIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT 276 >gi|183980256|ref|YP_001848547.1| oxidoreductase [Mycobacterium marinum M] gi|183173582|gb|ACC38692.1| oxidoreductase [Mycobacterium marinum M] Length=276 Score = 443 bits (1140), Expect = 1e-122, Method: Compositional matrix adjust. Identities = 219/276 (80%), Positives = 241/276 (88%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M TIDI+AGTIHYE TGPE GRPV+FVHGY+MGGQLWR+VSERLA RGLRC APTWPLGA Sbjct 1 MPTIDINAGTIHYEVTGPEHGRPVMFVHGYLMGGQLWRQVSERLAKRGLRCFAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+ L P AD++I GV +VADVLA L+L DVVLVGNDTGGVV QLVAV +PERLGALVL Sbjct 61 HPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGNDTGGVVAQLVAVRHPERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKS +FRAAIQ MR+PAAR RAY L+H +ID L + WV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSKKMFRAAIQTMRSPAARRRAYGDLAHADIDELAQRWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 +PALSNPAIAEDLRQL+LSL T+VT VAARLPEF KPALIAWSADD FFALE+G+RLAA Sbjct 181 QPALSNPAIAEDLRQLTLSLHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP AR E+IEGARTFSM+D PDRLAD LS VAVRT Sbjct 241 TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT 276 >gi|118619924|ref|YP_908256.1| oxidoreductase [Mycobacterium ulcerans Agy99] gi|118572034|gb|ABL06785.1| oxidoreductase [Mycobacterium ulcerans Agy99] Length=276 Score = 439 bits (1129), Expect = 2e-121, Method: Compositional matrix adjust. Identities = 217/276 (79%), Positives = 239/276 (87%), Gaps = 0/276 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M TIDI+AGTIHYE TGPE GRPV+FVHGY+MGGQLWR+VSERLA GLRC APTWPLG Sbjct 1 MPTIDINAGTIHYEITGPEHGRPVMFVHGYLMGGQLWRQVSERLAEWGLRCFAPTWPLGT 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+ L P AD++I GV +VADVLA L+L DVVLVGNDTGGVV QLVAVH+PERLGALVL Sbjct 61 HPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGNDTGGVVAQLVAVHHPERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKS +FRAAIQ MR+PAAR R Y L+H +ID L + WV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSKKMFRAAIQTMRSPAARRRTYGDLAHADIDELAQRWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 +PALSNPAIAEDLRQL+LSL T+VT VAARLPEF KPALIAWSADD FFALE+G+RLAA Sbjct 181 QPALSNPAIAEDLRQLTLSLHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 TIP AR E+IEGARTFSM+D PDRLAD LS VAVRT Sbjct 241 TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT 276 >gi|254819453|ref|ZP_05224454.1| hydrolase, alpha/beta hydrolase fold family protein [Mycobacterium intracellulare ATCC 13950] Length=276 Score = 431 bits (1108), Expect = 6e-119, Method: Compositional matrix adjust. Identities = 221/275 (81%), Positives = 238/275 (87%), Gaps = 0/275 (0%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MSTIDISAGTIHYEATGPE GRPVVFVHGYMMGGQLWR+VSERLA RGLRCIAPTWPLGA Sbjct 1 MSTIDISAGTIHYEATGPENGRPVVFVHGYMMGGQLWRQVSERLAARGLRCIAPTWPLGA 60 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLR GAD+TI GVA +VA+ LAAL L+DVVLVGNDTGGV+TQLVAVH+ ERLGALVL Sbjct 61 HPEPLRRGADRTITGVAAMVAEALAALNLEDVVLVGNDTGGVITQLVAVHHRERLGALVL 120 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 TSCDAFEHFPPPILKPVILAAKS T FRA Q MR P R RA+ GL+H NID LT WV Sbjct 121 TSCDAFEHFPPPILKPVILAAKSKTTFRAVAQAMRVPTVRKRAFDGLTHRNIDDLTELWV 180 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 RPA S PA+AEDLRQ +LS+R EVTT VAARL +FDKP L+AWSADD+FF E+G RLAA Sbjct 181 RPAQSLPAVAEDLRQFTLSMRPEVTTTVAARLYDFDKPTLVAWSADDLFFEQEDGARLAA 240 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVR 275 TIP AR EVI GARTFSMVD PDRLAD LSTVAVR Sbjct 241 TIPNARLEVIAGARTFSMVDQPDRLADLLSTVAVR 275 >gi|336459834|gb|EGO38747.1| putative hydrolase or acyltransferase of alpha/beta superfamily [Mycobacterium avium subsp. paratuberculosis S397] Length=198 Score = 305 bits (781), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 154/198 (78%), Positives = 171/198 (87%), Gaps = 0/198 (0%) Query 79 IVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVI 138 +VA++L+AL+L+DVVLVGNDTGGVV+QLVAVH+ ERLGALVLTSCDAFEHFPPP+L+PVI Sbjct 1 MVAELLSALDLEDVVLVGNDTGGVVSQLVAVHHRERLGALVLTSCDAFEHFPPPVLRPVI 60 Query 139 LAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSL 198 LAAKS FRA Q MRAPA R RA+ GL+H NID LT WVRPALS PA+AEDLR+ +L Sbjct 61 LAAKSKATFRAVAQAMRAPAVRKRAFDGLAHSNIDALTELWVRPALSLPAVAEDLRRFTL 120 Query 199 SLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSM 258 SLRTEVTTA A RL +FDKP LIAWSADDVFFA E+G RLAATIP AR EVI GARTFSM Sbjct 121 SLRTEVTTAAATRLYDFDKPTLIAWSADDVFFAQEDGARLAATIPNARHEVIAGARTFSM 180 Query 259 VDSPDRLADQLSTVAVRT 276 VD PDRLAD LSTVAVRT Sbjct 181 VDQPDRLADLLSTVAVRT 198 >gi|284047131|ref|YP_003397471.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684] gi|283951352|gb|ADB54096.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684] Length=285 Score = 198 bits (504), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 115/267 (44%), Positives = 146/267 (55%), Gaps = 3/267 (1%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 +S I + GTI Y GP G PVVFVHG++ G LW V+ LA RG R +AP WPLGA Sbjct 5 LSEITLPQGTIRYREQGPADGPPVVFVHGFLGDGTLWSGVAGDLAARGYRTLAPDWPLGA 64 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H L P AD T GVA +VA +AALEL DV LVGND+GG VTQ V P R+G +VL Sbjct 65 HTIALSPDADLTPRGVARLVAGFIAALELDDVTLVGNDSGGAVTQFVLDTDPSRVGRVVL 124 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNR--AYAGLSHHNID-HLTR 177 T+CD + FPP ++ AA+ LFRA ++ R A R+ A+ L+ D TR Sbjct 125 TNCDGIDVFPPKPFHLILKAARHPALFRALMEGTRITAIRHSPLAFGLLAKQPFDPAQTR 184 Query 178 AWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQR 237 WV P L++ + D + +A RL FD P L+ W DD FF +E +R Sbjct 185 GWVMPYLTDAGVRRDAAAFCRGVDPRELAGIATRLRRFDGPVLLCWGRDDRFFNVELARR 244 Query 238 LAATIPRARFEVIEGARTFSMVDSPDR 264 L A AR + A TF +D P R Sbjct 245 LQACFADARLVEVPDASTFVALDQPAR 271 >gi|312199420|ref|YP_004019481.1| alpha/beta hydrolase fold protein [Frankia sp. EuI1c] gi|311230756|gb|ADP83611.1| alpha/beta hydrolase fold protein [Frankia sp. EuI1c] Length=283 Score = 195 bits (495), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 114/270 (43%), Positives = 162/270 (60%), Gaps = 6/270 (2%) Query 2 STIDISAGTIHYEATGPETGR--PVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLG 59 I++ G I Y A GP T PVVFVHG ++ +LW V++ LA +G+R APT P+G Sbjct 8 EVIELPQGQIRYRAAGPPTSERPPVVFVHGVLVDRELWTPVADLLAQQGVRSYAPTLPMG 67 Query 60 AHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALV 119 AH P+ AD T GVA +V D++AAL+L+DV LVGNDTGG +TQ V P+R+G +V Sbjct 68 AHQTPMDADADLTPRGVARLVLDLIAALDLRDVTLVGNDTGGAITQFVLDTDPDRIGRVV 127 Query 120 LTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARN--RAYAGLSHHNID-HLT 176 LT+CDAF FPPP L ++ A + + A + +R+ R+ + LS +D LT Sbjct 128 LTNCDAFGAFPPPPLTLLVRALRHPAVVAAMVPGLRSTRLRHGPLGFGPLSTGPLDPALT 187 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQ 236 AWV+P L++ I DL +L+ + + V+ RL + D+P + W DD +F +E G+ Sbjct 188 GAWVKP-LADGKIRRDLAKLARGIDPKDLLDVSTRLGKLDRPVRVLWGDDDRYFDVELGR 246 Query 237 RLAATIPRARFEVIEGARTFSMVDSPDRLA 266 RLA A FE + G RTF +D PDR+A Sbjct 247 RLADAFTDATFETVAGGRTFLPLDHPDRVA 276 >gi|256391200|ref|YP_003112764.1| alpha/beta hydrolase fold protein [Catenulispora acidiphila DSM 44928] gi|256357426|gb|ACU70923.1| alpha/beta hydrolase fold protein [Catenulispora acidiphila DSM 44928] Length=288 Score = 173 bits (439), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 114/280 (41%), Positives = 155/280 (56%), Gaps = 14/280 (5%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M+ I++SAG I YE G G VV +HG +M LW V + LA R RC+ P PLGA Sbjct 1 MNEIELSAGVIEYEDRG-GPGPTVVLLHGLLMDETLWTAVVDELAPR-FRCVVPVLPLGA 58 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLV-AVHYPERLGALV 119 H K + P AD + G+A +VA+ L AL+L+DV LVGNDTGG++ QL+ A ER+ V Sbjct 59 HRKAMSPEADLSPLGIAALVAEFLDALDLRDVTLVGNDTGGMLVQLLMADGSRERIAGAV 118 Query 120 LTSCDAFEHFPPPIL-KPVILAAK-SATLFRAAIQVMR-APAARNRAYAGLSHHNIDHLT 176 L SCDAF++FPP + + + L K S LF +Q MR PA R G D Sbjct 119 LVSCDAFDNFPPGLTGRTLFLTGKLSPALFGMFMQQMRLKPARRMPLSFGWLTKRGDATV 178 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRT-----EVTTAVAARLPEFDKPALIAWSADDVFFA 231 + W+RP P I D ++ LRT + TA A +LP FD+P L+ W+ +D Sbjct 179 KRWLRPIWRQPEIRRDTVRV---LRTAAADPHILTAAAEKLPSFDRPTLVVWAQNDRVMP 235 Query 232 LENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLST 271 E+G+RLA +P AR I T +D P RLA ++ + Sbjct 236 PEHGRRLADLLPAARLVEIGDTYTLIPLDQPTRLATEIRS 275 >gi|126438113|ref|YP_001073804.1| alpha/beta hydrolase fold protein [Mycobacterium sp. JLS] gi|126237913|gb|ABO01314.1| alpha/beta hydrolase fold protein [Mycobacterium sp. JLS] Length=281 Score = 173 bits (439), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 99/276 (36%), Positives = 144/276 (53%), Gaps = 5/276 (1%) Query 1 MSTIDISAGTIHYEATGPETGR--PVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPL 58 M T+ + TI+Y GPE + PVVFVHG ++ +LW V++ L+ +G RC+ P WPL Sbjct 1 MPTLTLPTATINYRVAGPENSQFPPVVFVHGALVDHRLWDPVADILSAKGFRCVLPDWPL 60 Query 59 GAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGAL 118 G+H P+ ++ + VA +V D+L L L DV LVGNDTGG + QLV YP+ +G L Sbjct 61 GSHRTPV--DSELSPTSVAAMVHDLLTTLGLDDVTLVGNDTGGAICQLVVDAYPDLIGRL 118 Query 119 VLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYA-GLSHHNIDHLTR 177 VLT+CDAF+ FPP V + + ++MR R GL LT Sbjct 119 VLTNCDAFDKFPPFPFNVVFAMLRGQVSIKVLTELMRVRVLRQSPLGFGLLSRPHPELTA 178 Query 178 AWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQR 237 +W+ P ++ + +L L + T VA RLP+F KP + W D F G+R Sbjct 179 SWLEPCRTDAGVRANLATLLRHIAATDLTVVADRLPQFTKPVRLVWGMRDRCFTPALGRR 238 Query 238 LAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVA 273 L P A + A TF +D+P +AD + ++ Sbjct 239 LTGQFPDATMVEVPDASTFVALDAPHAVADAVEALS 274 >gi|108802132|ref|YP_642329.1| alpha/beta hydrolase fold protein [Mycobacterium sp. MCS] gi|119871285|ref|YP_941237.1| alpha/beta hydrolase fold protein [Mycobacterium sp. KMS] gi|108772551|gb|ABG11273.1| alpha/beta hydrolase fold protein [Mycobacterium sp. MCS] gi|119697374|gb|ABL94447.1| alpha/beta hydrolase fold protein [Mycobacterium sp. KMS] Length=281 Score = 173 bits (438), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 99/276 (36%), Positives = 144/276 (53%), Gaps = 5/276 (1%) Query 1 MSTIDISAGTIHYEATGPETGR--PVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPL 58 M T+ + TI+Y GPE + PVVFVHG ++ +LW V++ L+ +G RC+ P WPL Sbjct 1 MPTLTLPTATINYRVAGPENSQFPPVVFVHGALVDHRLWDPVADILSAKGFRCVLPDWPL 60 Query 59 GAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGAL 118 G+H P+ ++ + VA +V D+L L L DV LVGNDTGG + QLV YP+ +G L Sbjct 61 GSHRIPV--DSELSPTSVAAMVHDLLTTLGLDDVTLVGNDTGGAICQLVVDAYPDLIGRL 118 Query 119 VLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYA-GLSHHNIDHLTR 177 VLT+CDAF+ FPP V + + ++MR R GL LT Sbjct 119 VLTNCDAFDKFPPFPFNVVFAMLRGQVSIKVLTELMRVRVLRQSPLGFGLLSRPHPELTA 178 Query 178 AWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQR 237 +W+ P ++ + +L L + T VA RLP+F KP + W D F G+R Sbjct 179 SWLEPCRTDAGVRANLATLLRHIAATDLTVVADRLPQFTKPVRLVWGMRDRCFTPALGRR 238 Query 238 LAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVA 273 L P A + A TF +D+P +AD + ++ Sbjct 239 LTGQFPDATMVEVPDASTFVALDAPHAVADAVEALS 274 >gi|302529515|ref|ZP_07281857.1| conserved hypothetical protein [Streptomyces sp. AA4] gi|302438410|gb|EFL10226.1| conserved hypothetical protein [Streptomyces sp. AA4] Length=288 Score = 171 bits (433), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 96/273 (36%), Positives = 148/273 (55%), Gaps = 5/273 (1%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 +++ G + Y G GRPVVFVHG + LWR+V +A G RC+AP PLGAHP Sbjct 13 VNLPQGELRYFEHG--RGRPVVFVHGVLTSALLWRKVVPSVADAGFRCLAPDLPLGAHPV 70 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+R AD + G+A ++ D L AL+L+DV+LV NDTGG +TQL+ YPER+G +VLT Sbjct 71 PMRSDADLSAPGLATLLGDFLTALDLEDVILVANDTGGAITQLLLARYPERVGRVVLTPS 130 Query 124 DAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRA--YAGLSHHNI-DHLTRAWV 180 D+FE+F PPI +P+ A+ Q++R A + ++ + + ++ Sbjct 131 DSFEYFFPPIFRPLPKVARIPGSMAVLGQLLRIKALYRSPLLFGWVTKRPLPPDVADEYL 190 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 +P + DLR+ ++ + T A A +L +F +P L+ W ++ F + RLA Sbjct 191 GKLRKSPGLRRDLRKFLRTVDSSHTLAAAEKLRQFKRPVLLVWPPEEKLFPISLAHRLAE 250 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVA 273 +P A + + TF D P LA ++ A Sbjct 251 VLPDAELVEVPDSYTFVSEDQPAALAGHITRFA 283 >gi|326329362|ref|ZP_08195687.1| hydrolase, alpha/beta hydrolase fold family [Nocardioidaceae bacterium Broad-1] gi|325952937|gb|EGD44952.1| hydrolase, alpha/beta hydrolase fold family [Nocardioidaceae bacterium Broad-1] Length=293 Score = 167 bits (424), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 104/274 (38%), Positives = 151/274 (56%), Gaps = 13/274 (4%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M ++ +SAG I ++ TG + G +V +HG M G+LWRR L+G R I PT PLG Sbjct 1 MPSVQLSAGPIDFDDTGGD-GPVLVLLHGVPMDGRLWRRSMPYLSG--FRVIRPTLPLGG 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H KP+ P AD + GVA I+ D L AL+L DV LV ND GG L+ +R+G L L Sbjct 58 HRKPMNPDADLSQLGVANILGDFLDALDLHDVTLVLNDWGG-GQFLINEGRTDRIGRLAL 116 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARN--RAYAGLS----HHNIDH 174 +C+AF+++PP +P+ + +K LF A +Q+ R + R Y G+S +H D Sbjct 117 VACEAFDNYPPKAARPLAVLSKVPPLFTAGLQLFRMQSFRQARSGYGGMSVDKDYHLYDD 176 Query 175 LTRAWVRPALSNPAIAEDLRQLSLSL--RTEVTTAVAARLPEFDKPALIAWSADDVFFAL 232 L W PAL++ AI D + + R E+ +A +F KP L+ W+ D Sbjct 177 LVHGWFAPALTDKAIRRDFIKFAGGAPGRDELLE-LAEGQQKFTKPVLVVWADQDTLMPA 235 Query 233 ENGQRLAATIPRARFEVIEGARTFSMVDSPDRLA 266 E+G RLAA P AR E+++ + T +D P+ LA Sbjct 236 EHGPRLAAHYPDARLEIVKDSSTLVPIDQPELLA 269 >gi|300787011|ref|YP_003767302.1| alpha/beta hydrolase [Amycolatopsis mediterranei U32] gi|299796525|gb|ADJ46900.1| putative alpha/beta hydrolase [Amycolatopsis mediterranei U32] gi|340528503|gb|AEK43708.1| alpha/beta hydrolase [Amycolatopsis mediterranei S699] Length=289 Score = 167 bits (424), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 101/273 (37%), Positives = 148/273 (55%), Gaps = 5/273 (1%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 + ++AG + Y G TG PVVFVHG + +LWR+V +A G RC+AP PLG+H Sbjct 14 VRLAAGEVRYCERG--TGAPVVFVHGVLTNAELWRKVVPDVAAAGFRCLAPDLPLGSHDL 71 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+R GAD + G A ++AD L AL+L+DV LV NDTGG +TQ++ PER+G +VLT Sbjct 72 PMRAGADLSPAGNADVIADFLDALDLRDVTLVANDTGGALTQILLSRRPERVGRVVLTPS 131 Query 124 DAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRA--YAGLSHHNI-DHLTRAWV 180 D FE+F PPI K + A+ Q++R A + + + D + +A++ Sbjct 132 DCFEYFFPPIFKALPPLARIPGSMAVLGQLLRIRALYPLPVLFGWVVKRPLPDAVAQAYL 191 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 P + + DLR+L + T A A L D+P L+AW+ +D F + RLAA Sbjct 192 SPLRKSAGVRRDLRKLLREVHPRHTLAAAEALRTLDRPVLLAWAPEDKLFPIRLAHRLAA 251 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVA 273 +P A+ + + TF D P LA + A Sbjct 252 LLPDAKLVEVPDSYTFLSEDQPAVLARHVVEFA 284 >gi|300787755|ref|YP_003768046.1| alpha/beta hydrolase [Amycolatopsis mediterranei U32] gi|299797269|gb|ADJ47644.1| putative alpha/beta hydrolase [Amycolatopsis mediterranei U32] gi|340529323|gb|AEK44528.1| alpha/beta hydrolase [Amycolatopsis mediterranei S699] Length=276 Score = 167 bits (423), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 109/268 (41%), Positives = 150/268 (56%), Gaps = 8/268 (2%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 +++SAGT+ Y TG G +VFVHG +M G LW L G LR + PT PLGAH Sbjct 3 VELSAGTVEYTDTG-GAGPAIVFVHGLLMDGSLWDGPVTGLDG--LRRVVPTLPLGAHRH 59 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+R AD ++ G+A ++A+ L L+L+DV LVG DTGG + QL+ R+G +VL SC Sbjct 60 PMRDDADLSLPGLARLLAEFLERLDLRDVTLVGVDTGGALVQLLMADDAPRVGRVVLASC 119 Query 124 DAFEHFPPPIL-KPVILAAK-SATLFRAAIQVMRAPAARNRAYA-GLSHHNIDHLTRAWV 180 DAF++FPP + K + L K S LF A +Q MR A R A G D T W+ Sbjct 120 DAFDNFPPGLTGKTLFLTGKLSPRLFGAFMQQMRLRAVRRLPIAFGWLTKRGDAATARWI 179 Query 181 RPALSNPAIAED-LRQLSLSLRTE-VTTAVAARLPEFDKPALIAWSADDVFFALENGQRL 238 RP LS I D +R L + + A RLP FD+PAL+ W+ +D LE+G+RL Sbjct 180 RPLLSQAGIRRDTVRVLRAAAAAPGILLEAAERLPGFDRPALVVWATEDRVMPLEHGRRL 239 Query 239 AATIPRARFEVIEGARTFSMVDSPDRLA 266 AA +P+ + + + T +D P A Sbjct 240 AALLPQGKLVELADSYTLLPLDQPAEFA 267 >gi|118618372|ref|YP_906704.1| oxidoreductase [Mycobacterium ulcerans Agy99] gi|118570482|gb|ABL05233.1| oxidoreductase [Mycobacterium ulcerans Agy99] Length=284 Score = 165 bits (418), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 98/289 (34%), Positives = 145/289 (51%), Gaps = 30/289 (10%) Query 1 MSTIDISAGTIHYEATGPETG--RPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPL 58 M+ + +S TI Y GPE RPV+FVHG ++ +LW V+E LA G RCI PTWPL Sbjct 4 MAQVTLSQATIAYRVLGPENSPHRPVLFVHGILVDDRLWSAVAEGLAAMGFRCILPTWPL 63 Query 59 GAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGAL 118 G+H P GAD + G+A ++ + + AL+L DV LVGNDTGG + QL +P+ +G L Sbjct 64 GSHTIPANEGADLSPAGIAEMIHEFMVALDLADVTLVGNDTGGGLCQLAIDAHPDLVGRL 123 Query 119 VLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDH---- 174 VLT+CDAFE F A ++R P + +A + + H Sbjct 124 VLTNCDAFE-------------TFPPFPFPAVFTLLRRPRSIKTLFAAMGLRPLRHSPLG 170 Query 175 -----------LTRAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAW 223 LT +W++P ++ I +DL L + T V+ R +F KP + W Sbjct 171 FGLLLNKPDAALTASWLQPCRTDARICDDLATLLRHVAATDLTEVSTRFAQFTKPVTLVW 230 Query 224 SADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTV 272 D F +R+A P A + G++TF ++ P + + +STV Sbjct 231 GMGDRCFKPTLARRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTV 279 >gi|302545125|ref|ZP_07297467.1| alpha/beta hydrolase fold family hydrolase [Streptomyces hygroscopicus ATCC 53653] gi|302462743|gb|EFL25836.1| alpha/beta hydrolase fold family hydrolase [Streptomyces himastatinicus ATCC 53653] Length=285 Score = 164 bits (414), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 112/273 (42%), Positives = 152/273 (56%), Gaps = 8/273 (2%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 +++SAGTI YE TG E G V +HG M G LWR V L G+RCI PT PLG H + Sbjct 7 VELSAGTIEYEDTGGE-GPVAVLLHGVAMDGSLWREVVAGLRP-GVRCIVPTLPLGGHRR 64 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+RP AD ++ GVA +VA+ L L+L+DV L ND GG LVA ER+G LV+TSC Sbjct 65 PMRPDADLSVLGVARLVAEFLERLDLRDVTLAMNDWGG-AQALVADGRDERIGRLVITSC 123 Query 124 DAFEHFPPPIL-KPVILAAKSATLFRAAI--QVMRAPAARNRAYAGLSHHNI-DHLTRAW 179 +AFE+FPP + K + +A+ R A +R + ++ + L AW Sbjct 124 EAFENFPPGLPGKNLHTSARLPGGLRTAFALLKLRPLRRLPMTWGWMTKRPVPPELMDAW 183 Query 180 VRPALSNPAIAEDLRQLSLSLRTEVTTA-VAARLPEFDKPALIAWSADDVFFALENGQRL 238 RP ++P I DLR+ L + A RL FD+PAL+AW+++D E+G RL Sbjct 184 FRPLWTSPEIRRDLRKYVLGVPPAAELLRWAERLRAFDRPALVAWASEDRVMPPEHGLRL 243 Query 239 AATIPRARFEVIEGARTFSMVDSPDRLADQLST 271 AA +P+ R I + T VD P RLA + T Sbjct 244 AALLPQGRHVEIPDSYTLIPVDQPHRLAALMRT 276 >gi|298244041|ref|ZP_06967848.1| alpha/beta hydrolase fold protein [Ktedonobacter racemifer DSM 44963] gi|297557095|gb|EFH90959.1| alpha/beta hydrolase fold protein [Ktedonobacter racemifer DSM 44963] Length=316 Score = 163 bits (412), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 100/273 (37%), Positives = 135/273 (50%), Gaps = 13/273 (4%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 + + G + Y G G +VF+HG ++ LWR V L+G+ RCIA P GA Sbjct 11 VSLPQGVVRYRDEGK--GPTLVFIHGLLVNSALWRDVIAALSGQ-FRCIALDLPFGAQTV 67 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 PL AD + G+A ++AD L AL+L DV LVGNDTGG + QL V++PER+ L+LT+C Sbjct 68 PLHADADLSPSGIAQLIADFLVALDLHDVTLVGNDTGGAMCQLTIVNHPERITRLILTNC 127 Query 124 DAFEHFPPPILKPV-----ILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRA 178 DAFE F PP+LKP + + A A+Q R A+ A +S D T Sbjct 128 DAFEDFFPPLLKPFASGARLFGTRFADFLTWALQTKR---AQRVLMATVSLRRADDATLD 184 Query 179 WVRPAL--SNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQ 236 AL N I D Q + T A F P LI W +D+FF+ N + Sbjct 185 AYFSALRSGNREIRRDFIQFLKQVSNRYTIEAAKFFQHFQHPVLILWGKNDLFFSARNAR 244 Query 237 RLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 RL P A E + +R F D P LA ++ Sbjct 245 RLQQAFPHAWLEFVSQSRAFVPEDQPVLLAQKI 277 >gi|337763434|emb|CCB72142.1| putative hydrolase [Streptomyces cattleya NRRL 8057] Length=303 Score = 162 bits (411), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 103/274 (38%), Positives = 153/274 (56%), Gaps = 13/274 (4%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 + + +GT+ Y G TG +VFVHGY++ +WR++ LA RC+ P WPLG+H Sbjct 23 VRLPSGTLRYHERG--TGPVLVFVHGYLVNADIWRKLVPLLAS-DFRCLTPDWPLGSHDV 79 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+ PGAD + G+A ++AD LAAL+L+D LVGND+GG +Q+ A +P R+G LVL C Sbjct 80 PMDPGADLSPPGMARLIADFLAALDLRDATLVGNDSGGAYSQIAAAEHPGRVGRLVLACC 139 Query 124 DAFE-HFPP-----PILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLT- 176 + + +PP P+LK + ++V R RN Y L+ + ID +T Sbjct 140 ETPQCTWPPTPGGFPLLKATAVHPLPYWALYQVLRVRRTWRWRN-TYGWLAKYPIDGVTM 198 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLP-EFDKPALIAWSADDVFFALENG 235 R+++ P L+ P I D R+ S+ A RL +FDKP L+AW+A+D F L + Sbjct 199 RSYLDPVLTRPEIRFDGRKAIGSVSARYVRQAAVRLARDFDKPVLLAWAAEDHVFPLSHA 258 Query 236 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 + A T+ A IE + T+ D P+RLA L Sbjct 259 RGYAETL-GAPLHTIEDSYTYLSEDQPERLAQVL 291 >gi|291452359|ref|ZP_06591749.1| oxidoreductase [Streptomyces albus J1074] gi|291355308|gb|EFE82210.1| oxidoreductase [Streptomyces albus J1074] Length=280 Score = 162 bits (411), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 112/282 (40%), Positives = 158/282 (57%), Gaps = 10/282 (3%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M +++SAG + YE TG + G VV +HG M LW V L+G RC+ P PLG Sbjct 1 MPQLELSAGVVDYEDTGGD-GPVVVLLHGVAMDASLWDEVVPGLSGE-YRCVRPVLPLGG 58 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H +P+R GAD ++ GVA +VA+VL L+L+ V LV ND GG L A+ ER+G LVL Sbjct 59 HRRPMRAGADLSVPGVARLVAEVLERLDLRRVTLVLNDWGG-AQALFALGLGERIGRLVL 117 Query 121 TSCDAFEHFPPPIL-KPVILAAKSATLFRAAI--QVMRAPAARNRAYAGLSHHNID-HLT 176 TSC+AF+++PP + + ++ AA+ AA +R + +S + L Sbjct 118 TSCEAFDNYPPGLPDRNLVAAARLPGGLAAAFGLLRLRPARRLPMTWGRMSLRPVPARLM 177 Query 177 RAWVRPALSNPAIAEDLRQLSLSL--RTEVTTAVAARLPEFDKPALIAWSADDVFFALEN 234 W+RPA ++P I DLR L + R E+ A L EF+ PAL+AW+A+D +E+ Sbjct 178 DGWLRPAQTSPEIRRDLRAYLLGVPPREELLRWTEA-LREFEGPALVAWAAEDKVMPVEH 236 Query 235 GQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 G+RLAA +PRA + I G+RT VD P L L RT Sbjct 237 GRRLAALLPRAAYVEIAGSRTLIPVDQPAELLAHLRDFLART 278 >gi|183982780|ref|YP_001851071.1| oxidoreductase [Mycobacterium marinum M] gi|183176106|gb|ACC41216.1| oxidoreductase [Mycobacterium marinum M] Length=281 Score = 162 bits (409), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 97/289 (34%), Positives = 144/289 (50%), Gaps = 30/289 (10%) Query 1 MSTIDISAGTIHYEATGPETGR--PVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPL 58 M+ + +S TI Y GPE PV+FVHG ++ +LW V+E LA G RCI PTWPL Sbjct 1 MAQVTLSQATIAYRVLGPENSPHPPVLFVHGILVDERLWSAVAEGLAAMGFRCILPTWPL 60 Query 59 GAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGAL 118 G+H P GAD + G+A ++ + + AL+L DV LVGNDTGG + QL +P+ +G L Sbjct 61 GSHTIPANEGADLSPAGIAEMIHEFMVALDLADVTLVGNDTGGGLCQLAIDAHPDLVGRL 120 Query 119 VLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDH---- 174 VLT+CDAFE F A ++R P + +A + + H Sbjct 121 VLTNCDAFE-------------TFPPFPFPAVFTLLRGPRSIKPLFAAMGLRPLRHSPLG 167 Query 175 -----------LTRAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAW 223 LT +W++P ++ I +DL L + T V+ R +F KP + W Sbjct 168 YGLLLNKPDAALTASWLQPCRTDARICDDLATLLRHVAATDLTEVSTRFAQFTKPVTLVW 227 Query 224 SADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTV 272 D F +R+A P A + G++TF ++ P + + +STV Sbjct 228 GMGDRCFKPTLARRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTV 276 >gi|297204577|ref|ZP_06921974.1| oxidoreductase [Streptomyces sviceus ATCC 29083] gi|197710644|gb|EDY54678.1| oxidoreductase [Streptomyces sviceus ATCC 29083] Length=281 Score = 159 bits (403), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 106/274 (39%), Positives = 147/274 (54%), Gaps = 7/274 (2%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M I++S+GTI YE TG + G VV +HG+MM LW L+ RCIAPT P GA Sbjct 4 MREIELSSGTIAYEDTGGD-GPTVVLLHGWMMDASLWDGPIADLSADH-RCIAPTLPFGA 61 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H P+ AD ++ G+A +V + L L+L DV LVGNDTGG + QL+ R+G VL Sbjct 62 HRHPMSADADLSLPGIARLVTEFLDRLDLHDVTLVGNDTGGALVQLLMCEGVARVGQAVL 121 Query 121 TSCDAFEHFPPPIL-KPVILAAK-SATLFRAAIQVMRAPAARNRAYA-GLSHHNIDHLTR 177 SCDAF++FPP + K + L K LF +Q MR R +A G D T Sbjct 122 VSCDAFDNFPPGLTGKTLALTGKLPPRLFGLFMQQMRLRPLRRLPFAFGWLTLRGDAATA 181 Query 178 AWVRPALSNPAIAED-LRQL-SLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENG 235 W +P + I D +R L + + ++ A A RLP F++PAL+ W+ D E+G Sbjct 182 RWTKPVMEQQEIRYDAVRTLRAATTDAQLLLAAAERLPSFEQPALVVWAGADRVMPPEHG 241 Query 236 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 +RLA +P+ R I + T +D P LA + Sbjct 242 RRLAELLPQGRLVDIADSYTLIPLDQPTELAHHI 275 >gi|169627300|ref|YP_001700949.1| alpha/beta fold hydrolase [Mycobacterium abscessus ATCC 19977] gi|169239267|emb|CAM60295.1| Putative hydrolase, alpha/beta hydrolase fold [Mycobacterium abscessus] Length=274 Score = 158 bits (400), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 96/273 (36%), Positives = 144/273 (53%), Gaps = 7/273 (2%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M T + +AG I Y +G G P+VFVHG + G +WR++ E L+GR RCIAP PLGA Sbjct 1 MPTFESAAGPIQYRDSG--DGPPIVFVHGLFVTGTMWRKIVEPLSGR-FRCIAPDLPLGA 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H P+ PG + VAG+V D++ L+L DV +V DTGG +TQL+ +R+G +VL Sbjct 58 HKTPMNPGVELGPRAVAGLVRDLIVNLDLDDVTVVATDTGGAITQLLLADGCDRIGRVVL 117 Query 121 TSCDAFEHFPPPILKPVILAAK-SATLFRAAIQVMRAPAARNRAYAGLSHHNI-DHLTRA 178 T CD+F++F P ++ A+ T F +Q + AR L+ H+I D + Sbjct 118 TPCDSFDNFLPKSIRIFQYWARVPGTDF--VLQPFKLRLARRALGNTLAKHSIPDAVLGE 175 Query 179 WVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRL 238 WV P L+ I D+R + T A A L F++P L+ W FF + +R Sbjct 176 WVAPLLAQQGIRRDVRAFLRGIDNRDTLAAAEILRGFERPVLLLWPRTLPFFPFAHAERW 235 Query 239 AATIPRARFEVIEGARTFSMVDSPDRLADQLST 271 +P A+ + + TF D P+ + ++ T Sbjct 236 LRLLPNAKLVEVPDSYTFVSEDQPELMVREIET 268 >gi|291448612|ref|ZP_06588002.1| oxidoreductase [Streptomyces roseosporus NRRL 15998] gi|291351559|gb|EFE78463.1| oxidoreductase [Streptomyces roseosporus NRRL 15998] Length=276 Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 106/276 (39%), Positives = 148/276 (54%), Gaps = 8/276 (2%) Query 6 ISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPL 65 +SAG I Y TG + G VV +HG M G LW V L G G RCI PT PLG H +P+ Sbjct 3 LSAGVIEYRDTGGD-GPVVVLLHGVAMNGSLWDEVVAGL-GDGARCIVPTLPLGGHRRPM 60 Query 66 RPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDA 125 GAD ++ GVA +VA+ L AL L+DV LV ND GG LVA +R+G LV+TSC+A Sbjct 61 EAGADLSVLGVARLVAEFLEALRLEDVTLVMNDWGG-AQALVADGRADRIGRLVITSCEA 119 Query 126 FEHFPPPILKPVILA-AKSATLFRAAIQVMRAPAARN--RAYAGLSHHNIDHLTR-AWVR 181 F+++PP + + A A+ RAA ++R AR + +S + H T W R Sbjct 120 FDNYPPGLPGRNLAAFARLPGGIRAAFSLLRLKPARRLPMTWGWMSKRPVPHATMDDWFR 179 Query 182 PALSNPAIAEDLRQLSLSLRTEVTTA-VAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 P L++ AI DLR L + + +L FD+PAL+ W+ +D L++G+RLA Sbjct 180 PLLTSAAIRRDLRAYVLGVPEKAELLRWTEQLRTFDRPALVVWATEDRVMPLDHGRRLAD 239 Query 241 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 +P+ R + + T D PD + L T Sbjct 240 ILPQGRLVEVADSYTLIPQDRPDAFVEHLRAFLAET 275 >gi|345002793|ref|YP_004805647.1| alpha/beta hydrolase fold protein [Streptomyces sp. SirexAA-E] gi|344318419|gb|AEN13107.1| alpha/beta hydrolase fold protein [Streptomyces sp. SirexAA-E] Length=279 Score = 155 bits (393), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 109/280 (39%), Positives = 149/280 (54%), Gaps = 8/280 (2%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 MS + +SAG + YE TG + G VV +HG M G LWR V L G RC+ PT PLG Sbjct 1 MSEVLLSAGVVEYEDTGGD-GPVVVLLHGVAMNGSLWRHVVAGL-GADFRCVVPTLPLGG 58 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H +P+ P AD T+ GVA +VA+ L AL L+DV LV ND GG LVA R+G LVL Sbjct 59 HRRPMLPDADLTVRGVARLVAEFLDALGLQDVTLVMNDWGG-AQFLVADGRDRRIGRLVL 117 Query 121 TSCDAFEHFPPPIL-KPVILAAKSATLFRAAIQVMRAPAARNR--AYAGLSHHNI-DHLT 176 TSC+AF +FPP + + + LAAK R A +++ R + +S + + Sbjct 118 TSCEAFGNFPPGLPGRNLYLAAKVPGGLRLAFALLKLKPLRRLPVTWGWMSKRPVPPEVM 177 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAAR-LPEFDKPALIAWSADDVFFALENG 235 W RP ++ AI DLR +L + E A L FD+PAL+ W+ +D +G Sbjct 178 DEWFRPLWTSAAIRRDLRAYALGVPPERELLEWAEALRTFDRPALVVWATEDKVMPPSHG 237 Query 236 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVR 275 +RLA +PR +E + T D P+RL + L R Sbjct 238 RRLAGLLPRGELVEVEDSYTLIPQDRPERLCEALRAFVPR 277 >gi|284047111|ref|YP_003397451.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684] gi|283951332|gb|ADB54076.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684] Length=289 Score = 153 bits (386), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 105/272 (39%), Positives = 148/272 (55%), Gaps = 14/272 (5%) Query 1 MSTIDISAGTIHYEATG--PETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPL 58 M + + GTI YE +G P G VV +HG M G +WR+V LA R I PT PL Sbjct 1 MPDVRLPQGTIEYEDSGEPPGGGPTVVLLHGLFMDGTVWRKVVPELA-HDARVIRPTLPL 59 Query 59 GAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGAL 118 GAH P+ P AD ++ G+ +VA L AL+L+DVVLV ND GG + LV ER+G Sbjct 60 GAHRIPMEPDADLSLRGMTRLVAAFLDALDLRDVVLVLNDWGGPLL-LVEEGLDERVGRF 118 Query 119 VLTSCDAFEHFPPPILKPVILAAKSATL----FRAAIQVMRAPAARNRA--YAGLSHHNI 172 V +C+ F++FPP I P LAA + L R A+Q +R+ R + +S + Sbjct 119 VFVACELFDNFPPGI--PGRLAALAGRLGPAGVRFAVQPLRSRTLRRFPLLFGWMSKRPV 176 Query 173 D-HLTRAWVRPALSNPAIAEDLRQLSLSLRT-EVTTAVAARLPEFDKPALIAWSADDVFF 230 D ++ W P L+ AI DL + + S T + TTA RL +FD+PAL+ W+ +D Sbjct 177 DPEVSDRWFEPVLTQHAIRRDLAKYAGSRFTADETTAATERLRDFDRPALVVWAPEDKLM 236 Query 231 ALENGQRLAATIPRARFEVIEGARTFSMVDSP 262 ++G+RLA +P+ R IE + T D P Sbjct 237 PRDHGRRLAELLPQGRLVEIEDSYTLIPEDQP 268 >gi|226364624|ref|YP_002782406.1| hydrolase [Rhodococcus opacus B4] gi|226243113|dbj|BAH53461.1| putative hydrolase [Rhodococcus opacus B4] Length=277 Score = 152 bits (384), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 103/276 (38%), Positives = 151/276 (55%), Gaps = 12/276 (4%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M I++SAGT+ Y+ TG + G +VF+ G + G +WR V ERLA RCI PT PLGA Sbjct 1 MKQIELSAGTVEYDDTGGD-GPVLVFISGLTIDGTVWRHVVERLAP-DFRCILPTLPLGA 58 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H P+ AD ++ G+ ++ + L L+L DV LV ND GG L+A+ R+GALVL Sbjct 59 HRIPMHADADLSLRGLGLLIGEFLEKLDLADVTLVQNDWGGAQV-LIALGDTSRVGALVL 117 Query 121 TSCDAFEHFPPPILKPVI-LAAKSATLFRAAIQVMRAPAARNR--AYAGLSHHNIDH-LT 176 T C+AF+++PP I I LA +Q +R A R A+ +S + + Sbjct 118 TPCEAFDNYPPGIPGRAIGLAVAVPGGLALTMQALRFRAMRRAPGAWGWMSKRAVPKPVM 177 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTT---AVAARLPEFDKPALIAWSADDVFFALE 233 W RPA ++ + DLR+ + SL + T A A R FD+P L+ W+ +D + Sbjct 178 DGWFRPATTDRRVRRDLRKYTTSLPPKSTLREWAEANR--SFDRPVLVLWAVEDKVMPRD 235 Query 234 NGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 +G+RLAA P AR +E + T D PD +A+ + Sbjct 236 HGRRLAALYPHARLREVEDSYTLMPEDRPDVVAEAI 271 >gi|239991610|ref|ZP_04712274.1| haloalkane dehalogenase [Streptomyces roseosporus NRRL 11379] Length=270 Score = 152 bits (383), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 103/271 (39%), Positives = 144/271 (54%), Gaps = 8/271 (2%) Query 11 IHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRPGAD 70 I Y TG + G VV +HG M G LW V L G G RCI PT PLG H +P+ GAD Sbjct 2 IEYRDTGGD-GPVVVLLHGVAMNGSLWDEVVAGL-GDGARCIVPTLPLGGHRRPMEAGAD 59 Query 71 QTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFP 130 ++ GVA +VA+ L AL L+DV LV ND GG LVA +R+G LV+TSC+AF+++P Sbjct 60 LSVLGVARLVAEFLEALRLEDVTLVMNDWGG-AQALVADGRADRIGRLVITSCEAFDNYP 118 Query 131 PPILKPVILA-AKSATLFRAAIQVMRAPAARN--RAYAGLSHHNIDHLT-RAWVRPALSN 186 P + + A A+ RAA ++R AR + +S + H T W RP L++ Sbjct 119 PGLPGRNLAAFARLPGGIRAAFSLLRLKPARRLPMTWGWMSKRPVPHATMDDWFRPLLTS 178 Query 187 PAIAEDLRQLSLSLRTEVTTA-VAARLPEFDKPALIAWSADDVFFALENGQRLAATIPRA 245 AI DLR L + + +L FD+PAL+ W+ +D L++G+RLA +P+ Sbjct 179 AAIRRDLRAYVLGVPEKAELLRWTEQLRTFDRPALVVWATEDRVMPLDHGRRLADILPQG 238 Query 246 RFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 R + + T D PD + L T Sbjct 239 RLVEVADSYTLIPQDRPDAFVEHLRAFLAET 269 >gi|54023417|ref|YP_117659.1| putative hydrolase [Nocardia farcinica IFM 10152] gi|54014925|dbj|BAD56295.1| putative hydrolase [Nocardia farcinica IFM 10152] Length=288 Score = 151 bits (381), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 94/267 (36%), Positives = 135/267 (51%), Gaps = 6/267 (2%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 ID+ G I Y TG +G PVVFVHG ++ LWR+V +A G RC+AP WPLGAH Sbjct 13 IDLPGGRIRYYETG--SGSPVVFVHGLLVNANLWRKVVPDIAAAGYRCLAPDWPLGAHSI 70 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+ P AD + G+A ++A L L+L DV LV NDTGG +TQ++ R+ +VL S Sbjct 71 PV-PEADLSPAGLADLIAAFLDRLDLTDVTLVANDTGGAITQVLLARQRARIARVVLASV 129 Query 124 DAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYA---GLSHHNIDHLTRAWV 180 D +E F PP K + A+ R A +++R A A + + ++ Sbjct 130 DCYERFLPPPFKLLTPLARIPGSLRPATELLRIRALHPLPIALGWVVKRPVPPEVVDTYL 189 Query 181 RPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA 240 P+ + AI DLR+ R T A E D P L+ W+ +D F + +RLAA Sbjct 190 LPSRRSGAIRHDLRRFLAGARNSYTLEAARHFGEIDLPVLLVWAREDKLFPVRLAERLAA 249 Query 241 TIPRARFEVIEGARTFSMVDSPDRLAD 267 +P A ++ + T D P L + Sbjct 250 DLPNATLRFVDDSYTAIPEDQPAALTE 276 >gi|54026900|ref|YP_121142.1| putative hydrolase [Nocardia farcinica IFM 10152] gi|54018408|dbj|BAD59778.1| putative hydrolase [Nocardia farcinica IFM 10152] Length=283 Score = 149 bits (375), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 102/280 (37%), Positives = 144/280 (52%), Gaps = 17/280 (6%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M T++++AG +HY G G PVV +HG +M +W V + L G R + P PLGA Sbjct 1 MPTVELAAGRLHYVERG--EGPPVVLLHGLLMNHTVWDEVLDLLP-TGFRYVLPDLPLGA 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 HP+PLRPG D ++ G+ +VA LAAL+L+DV LV +D GG + L A ER+G L+ Sbjct 58 HPEPLRPGVDLSLHGLNRLVAGFLAALDLRDVTLVHSDWGGALF-LTAYGLDERVGGLIA 116 Query 121 TSCDAFEHFPPPIL-KPVILAAKSATLFRAAIQVMRAPAARNR-------AYAGLSHHNI 172 C+AF +FPP + + ++A + A++ +R P R A G+S Sbjct 117 LPCEAFGNFPPGLPGRMAVIATRVPGGVPLALRQLRIPWLRRSPLLFGWMARGGVS---- 172 Query 173 DHLTRAWVRPALSNPAIAEDLRQLSLS-LRTEVTTAVAARLPEFDKPALIAWSADDVFFA 231 D L R W P L +P I DL + S A L F PALI WS+ Sbjct 173 DELVRGWTEPGLRDPGIRRDLLAYARSGFHQRELIANTEALRRFSGPALILWSSAGKVMP 232 Query 232 LENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLST 271 E+G+ LA IP AR I+ A SM+D P +A + + Sbjct 233 REHGRGLAELIPDARLVEIDDAYVLSMLDQPRAVAAAMGS 272 >gi|291301237|ref|YP_003512515.1| alpha/beta hydrolase fold protein [Stackebrandtia nassauensis DSM 44728] gi|290570457|gb|ADD43422.1| alpha/beta hydrolase fold protein [Stackebrandtia nassauensis DSM 44728] Length=285 Score = 147 bits (372), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 101/274 (37%), Positives = 144/274 (53%), Gaps = 9/274 (3%) Query 2 STIDISAGTIHYEATGPETGRPV-VFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 ID+SAGTI Y TG +PV V VHG +M LW V LA RC+ P PLGA Sbjct 5 KNIDLSAGTIDYLDTGGT--KPVLVLVHGLLMDETLWTDVVAELAPE-YRCVVPVLPLGA 61 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H + GAD ++ GVA ++A+ + L L DV LVGNDTGG V QL+ + VL Sbjct 62 HRHAMSHGADLSLPGVARLLAEFVDRLGLTDVTLVGNDTGGAVVQLLMAEPAASVARAVL 121 Query 121 TSCDAFEHFPPPIL-KPVILAAK-SATLFRAAIQVMRAPAARNRAYA-GLSHHNIDHLTR 177 SC+AF++ PP + + ++L K LF ++ +R R + G D +T Sbjct 122 VSCEAFDNLPPGLTGRALVLTGKLPPRLFGLFMRQLRLKPMRRLPFVFGWLTRRGDAVTA 181 Query 178 AWVRPALSNPAIAED-LRQL-SLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENG 235 WV P + + A+A D R L S++ ++ A RLP FD+P L+ W+ +D E+G Sbjct 182 GWVTPVIGDVAVARDATRTLRSIASNRKLLLDNATRLPGFDRPVLVVWAKNDRVMPPEHG 241 Query 236 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 +RLA +P AR V++ +D P LA + Sbjct 242 ERLAELLPDARLTVVDDTDALIPLDQPTALAGHI 275 >gi|254385252|ref|ZP_05000583.1| alpha/beta hydrolase [Streptomyces sp. Mg1] gi|194344128|gb|EDX25094.1| alpha/beta hydrolase [Streptomyces sp. Mg1] Length=285 Score = 147 bits (370), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 102/280 (37%), Positives = 142/280 (51%), Gaps = 8/280 (2%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M I++S+G I Y+ TG E G +V HG M WR+V L G RC+ PT PLG Sbjct 1 MPRIELSSGPIDYQDTGGE-GPVLVLAHGLPMNETQWRKVVPLLDG--YRCVLPTLPLGG 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H +P+ P AD + GVA ++ + +A L L V LV ND GG LV+ R+ LVL Sbjct 58 HRQPMNPDADLSQRGVALLLGEFIAGLGLDRVTLVLNDWGG-GQFLVSEGQDRRIARLVL 116 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAAR-NR-AYAGLSHHNI-DHLTR 177 +C+AF++FPP K + + ++MR PA R NR Y G+S + D + Sbjct 117 VACEAFDNFPPGPAKAMAQVCRIPGGVWLLTRLMRVPAFRHNRGGYGGMSLRGVPDEIMD 176 Query 178 AWVRPALSNPAIAEDLRQLSLSL-RTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQ 236 W PA + AI D + + E A + RL EFD+P L+ W+ +D E+G Sbjct 177 DWFAPATRSRAIRRDFAKFATGAPGRETLLAWSDRLREFDRPVLVVWATEDRLMPREHGP 236 Query 237 RLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 RLA P+ R I + T D P+RLA L+ RT Sbjct 237 RLAELYPQGRLVEIADSSTLIPEDQPERLAQVLTDFLTRT 276 >gi|343925819|ref|ZP_08765334.1| putative hydrolase [Gordonia alkanivorans NBRC 16433] gi|343764170|dbj|GAA12260.1| putative hydrolase [Gordonia alkanivorans NBRC 16433] Length=292 Score = 147 bits (370), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 95/271 (36%), Positives = 133/271 (50%), Gaps = 9/271 (3%) Query 1 MSTIDISAGTIHYEATGP--ETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPL 58 + T+++ +G I GP T P+VF+HG ++ +LW V+E LA RG RC P PL Sbjct 5 LPTVELPSGVIECATYGPADSTLPPIVFMHGAVVDHRLWEPVAELLAERGHRCHVPLMPL 64 Query 59 GAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGAL 118 G+H P P AD++ G + ++ + + L+L VLV NDTGG VTQ P + L Sbjct 65 GSHRIPWGPDADRSPRGASRLLREFVGHLDLSSAVLVANDTGGAVTQFALDEDPHFVRRL 124 Query 119 VLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAYA-GLSHHNID-HLT 176 V T+CDAF+ FPP + + L + + MR A R+ GL H+ D LT Sbjct 125 VFTNCDAFDLFPPQPFRLYFALMRQRLLLKPLVDAMRLKALRHSPLGVGLLLHDPDPDLT 184 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQ 236 + P S+ I +D + V AR+ D P W DD F E+G+ Sbjct 185 ASVFAPLQSDARIRDDFIAFLREINPAELATVTARMSRVDLPVRFVWGRDDRCFTPEHGR 244 Query 237 RLAATIP-----RARFEVIEGARTFSMVDSP 262 R A+ P ARF I GARTF +D P Sbjct 245 RFASVFPGPDGEGARFVEIPGARTFVSLDQP 275 >gi|111022131|ref|YP_705103.1| haloalkane dehalogenase [Rhodococcus jostii RHA1] gi|110821661|gb|ABG96945.1| probable haloalkane dehalogenase [Rhodococcus jostii RHA1] Length=276 Score = 147 bits (370), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 100/280 (36%), Positives = 150/280 (54%), Gaps = 20/280 (7%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M I++SAGT+ Y TG + G +VF+ G + G +WR V E+LA RCI P PLGA Sbjct 1 MKQIELSAGTVEYRDTGGD-GPVLVFISGLTIDGTVWRHVVEQLAP-DFRCIVPNLPLGA 58 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H P+R AD ++ G+ ++ + L L+L DV LV ND GG L+A+ R+GALVL Sbjct 59 HRIPMREDADLSLRGLGLLIGEFLERLDLADVTLVQNDWGGAQV-LIALGDSSRIGALVL 117 Query 121 TSCDAFEHFPPPI------LKPVILAAKSATLFRAAIQVM-RAPAARNRAYAGLSHHNI- 172 T C+AF+++PP I L I + T+ + M RAPA + +S + Sbjct 118 TPCEAFDNYPPGIPGRAIGLAVAIPGGLALTMHALRFRAMRRAPA----GWGWMSKRPVP 173 Query 173 DHLTRAWVRPALSNPAIAEDLRQLSLSLRTEVTT---AVAARLPEFDKPALIAWSADDVF 229 + W RPA ++ + DLR+ + S+ + T A A R FD+P L+ W+ +D Sbjct 174 KSVMDGWFRPATTDRLVRRDLRKYTTSVPPKSTLREWAEANR--SFDRPVLVLWAVEDKV 231 Query 230 FALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 ++G+RLA P A + +E + T D PD +A+ L Sbjct 232 MPRDHGRRLAELYPHAELQEVEDSYTLMPEDRPDVVAEAL 271 >gi|326381618|ref|ZP_08203312.1| alpha/beta hydrolase fold protein [Gordonia neofelifaecis NRRL B-59395] gi|326199865|gb|EGD57045.1| alpha/beta hydrolase fold protein [Gordonia neofelifaecis NRRL B-59395] Length=276 Score = 146 bits (368), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 103/281 (37%), Positives = 142/281 (51%), Gaps = 10/281 (3%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M +ID+ AG I Y TG + G ++F HG +M WRRV L RCIAPTWPLGA Sbjct 1 MGSIDLPAGPIDYLDTGGD-GPVLLFGHGLLMNRTQWRRVIPLLDD--FRCIAPTWPLGA 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 + + AD T G A I+AD L AL+L DV LV ND GG +V+ ERL LVL Sbjct 58 QRQAMNASADLTQAGQANIIADFLEALDLHDVTLVLNDWGG-GQFIVSEGRDERLARLVL 116 Query 121 TSCDAFEHFPPPILKPVILAAK---SATLFRAAIQVMRAPAARNRAYAGLSHHNI-DHLT 176 SC+A+++FPP +P L + LF Q+ + AY GLS + I D + Sbjct 117 ASCEAYDNFPPKPARPAALLCRVPGGTWLFTRLTQLSLFRHGKP-AYGGLSKNRIPDAVM 175 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAAR-LPEFDKPALIAWSADDVFFALENG 235 W AL++ I DLR+ + T R + FD+P L+ W+ DD +E+ Sbjct 176 DDWFGHALADADIRRDLRKFVTGTPPKETLLDWHRQVVSFDRPVLLLWATDDRMMPVEHA 235 Query 236 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 + + A P AR + + T D P+R A++L T Sbjct 236 RHMVAEFPDARLVEVGDSWTLLPEDQPERFAEELREFVSST 276 >gi|343497499|ref|ZP_08735565.1| hydrolase/oxidase [Vibrio nigripulchritudo ATCC 27043] gi|342818239|gb|EGU53108.1| hydrolase/oxidase [Vibrio nigripulchritudo ATCC 27043] Length=304 Score = 145 bits (366), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 87/269 (33%), Positives = 132/269 (50%), Gaps = 7/269 (2%) Query 6 ISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPL 65 + GTI Y+ G G+ ++F+HG + WR+V L+ + RCIAP PLG H L Sbjct 32 LECGTIRYKDVG--QGKVLLFLHGALANSNNWRKVLPELS-KTYRCIAPDLPLGGHAISL 88 Query 66 RPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDA 125 AD + G+ I+ L AL L VVLVGNDTGG Q+ YPER+ A++L +CDA Sbjct 89 DQSADLSPDGICQILTQFLDALNLDSVVLVGNDTGGAYGQIFTAKYPERVSAMILNNCDA 148 Query 126 FEHFPPPILKPVILAAKSATLFRAAIQVMR-APAARNRAYAGLSHHNI--DHLTRAWVRP 182 F+ FPP + Q+ R P + GL +++ + + +V Sbjct 149 FDVFPPEQFSTLPKLVHVPGYLSLMAQLFRIKPLLTSNLVLGLLSNSLMKEEVYHQYVYN 208 Query 183 ALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADD-VFFALENGQRLAAT 241 ++N I D +++ T+ T A A L FD+P I W+ DD F G+RL + Sbjct 209 FINNKMIRNDFKKVVNGWSTDYTLAAANALRGFDRPVSIVWATDDETLFPESLGRRLLSI 268 Query 242 IPRARFEVIEGARTFSMVDSPDRLADQLS 270 A+F + G+ T+ D + D++S Sbjct 269 FSNAKFTSVTGSLTYVHHDQSEVYIDKVS 297 >gi|111221877|ref|YP_712671.1| putative oxidoreductase [Frankia alni ACN14a] gi|111149409|emb|CAJ61101.1| putative oxidoreductase [Frankia alni ACN14a] Length=350 Score = 145 bits (366), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 104/280 (38%), Positives = 144/280 (52%), Gaps = 16/280 (5%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M+ I++S GTI YE TG G +V +HG +M LW LAG RC+ PT P+GA Sbjct 40 MAEIELSTGTIDYEDTG-GPGPVLVLLHGLLMDASLWAGPVAELAG-DHRCVVPTLPMGA 97 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLV-----AVHYPERL 115 H P+ P AD ++ G+A +V ++L L+L DV LVGNDTGG + QLV A R+ Sbjct 98 HRHPVHPDADLSLPGLARLVVELLDRLDLHDVTLVGNDTGGALVQLVVRDGAARDGAARV 157 Query 116 GALVLTSCDAFEHFPPPILKPVILAAKS--ATLFRAAIQVMR-APAARNRAYAGLSHHNI 172 G + L SC+AF++ PP + + A + L +Q MR P R G Sbjct 158 GRIALVSCEAFDNMPPSLTGRTLALAGALPPALLGLVMQQMRLRPMRRAPIAFGWLTARG 217 Query 173 DHLTRAWVRPAL----SNPAIAEDLRQLSLSLR--TEVTTAVAARLPEFDKPALIAWSAD 226 D T W++P L + I D ++ SLR E+ A LP F PAL+ W+A+ Sbjct 218 DAATARWMQPLLRRGENRGGIRRDTVRVLRSLRPARELLLDAPAYLPSFTGPALVVWAAE 277 Query 227 DVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLA 266 D E+G+RLA +PR R + RT +D P LA Sbjct 278 DRVMPPEHGRRLAELLPRGRLVEVADTRTLIPLDQPAELA 317 >gi|118466225|ref|YP_881063.1| alpha/beta hydrolase [Mycobacterium avium 104] gi|118167512|gb|ABK68409.1| hydrolase, alpha/beta fold family protein, putative [Mycobacterium avium 104] Length=283 Score = 145 bits (365), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 91/270 (34%), Positives = 140/270 (52%), Gaps = 8/270 (2%) Query 6 ISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPL 65 I+ G + + +G VVFVHG + G LW+ V +RL+ RCIAPT P GA P+ Sbjct 4 IAVGDVEIDYVDAGSGPVVVFVHGAYVTGLLWQDVVDRLSDSH-RCIAPTLPFGAQAAPV 62 Query 66 RPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYP----ERLGALVLT 121 D ++ ++A +L AL+L DV LV NDTGG + L A+ +R+ LV T Sbjct 63 GAHVDLSVAASGRLIAGLLDALDLSDVTLVANDTGGGIV-LAALGNASLKWDRVSKLVFT 121 Query 122 SCDAFEHFPPPILKPVI-LAAKSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWV 180 +CD+FEHFPP P++ L A S +L A++ + + ++ + +D R V Sbjct 122 NCDSFEHFPPKSFAPIVRLCALSQSLGAIALKGLTTAPGLKVFTSAVTLNGVDAARRRAV 181 Query 181 RPA-LSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLA 239 L++PA+ + + + L+ T A L +D+P L+AW D F L + +RLA Sbjct 182 FGGFLTSPAVRREAARFTADLKPSHTLAAVDALKRWDRPVLMAWGTSDKMFPLSHAERLA 241 Query 240 ATIPRARFEVIEGARTFSMVDSPDRLADQL 269 T P A I+ + T+ M+D PD A + Sbjct 242 ETFPNAVVRAIDNSSTYVMLDRPDETAQAI 271 >gi|302528323|ref|ZP_07280665.1| alpha/beta hydrolase fold protein [Streptomyces sp. AA4] gi|302437218|gb|EFL09034.1| alpha/beta hydrolase fold protein [Streptomyces sp. AA4] Length=281 Score = 144 bits (364), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 102/294 (35%), Positives = 142/294 (49%), Gaps = 37/294 (12%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 +++SAG I Y TG +G +VF HG+ M G WR+V L G RC+ PT PLGAH Sbjct 1 MELSAGPIDYTDTG-GSGPALVFGHGFPMSGTQWRKVVPLL--DGYRCLLPTLPLGAHLA 57 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGG----VVTQLVAVHYPERLGALV 119 P+RP AD T GVA ++ + LAAL+L D +V ND GG V L + R+G L Sbjct 58 PMRPDADLTQFGVARLLGEFLAALDLHDATIVLNDWGGGQFLVADGLAPAEHVARVGRLA 117 Query 120 LTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAA---------------RNRAY 164 L +C+AF++FPP KP RAA++++R P AY Sbjct 118 LVACEAFDNFPP---KPA----------RAAVKLLRLPGGPWLHAQATRTSFYRHAKAAY 164 Query 165 AGLSHHNI-DHLTRAWVRPALSNPAIAEDLRQLSL-SLRTEVTTAVAARLPEFDKPALIA 222 G+ I D + W PAL + I D+ + + S V RL F++P L+ Sbjct 165 GGMCESRIPDDVLEGWFSPALRDKEIRRDMVKFATGSPPRRVLLEWTERLRAFERPVLVV 224 Query 223 WSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT 276 W+ D E+G+RLA P R I + T D P+ LA +L+ T Sbjct 225 WAGKDRMMPAEHGRRLADLFPDGRLVEIPDSGTLIPEDQPELLAKELTAFLAET 278 >gi|297190088|ref|ZP_06907486.1| oxidoreductase [Streptomyces pristinaespiralis ATCC 25486] gi|197721201|gb|EDY65109.1| oxidoreductase [Streptomyces pristinaespiralis ATCC 25486] Length=294 Score = 144 bits (363), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 96/271 (36%), Positives = 139/271 (52%), Gaps = 10/271 (3%) Query 4 IDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPK 63 I++SAGT+ Y TG +G VV +HG +W V + L R + P P+G+H + Sbjct 12 IELSAGTVEYTDTG-GSGETVVLLHGLGFDESVWHAVVDGLRA-DFRVVVPVLPMGSHRR 69 Query 64 PLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSC 123 P+RP AD + GVA ++A+ L L+L+DV LV ND G QL+ ER+ LVLTSC Sbjct 70 PMRPDADLSAQGVADLLAEFLERLDLRDVTLVQNDAG--TAQLLVGVRDERVHRLVLTSC 127 Query 124 DAFEHFPPPILKPV--ILAAKSATLFRAAIQVMRAPAARN--RAYAGLSHHNIDH-LTRA 178 +A E++PP + + +L+ +F +Q R P + G++ H I + L R Sbjct 128 EALENYPPGVQGRMLQVLSRVPGGIF-LLLQTFRVPLLVRLPNSLGGMAEHPIPYGLVRR 186 Query 179 WVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRL 238 W P L++ I D S R + A RL F PAL+AW A D G+RL Sbjct 187 WYGPLLTDKRIRRDFAAFLHSTRKDTYLRAAERLRGFRGPALVAWGAKDRMMPHATGRRL 246 Query 239 AATIPRARFEVIEGARTFSMVDSPDRLADQL 269 A +PR + I ART +D+P L +L Sbjct 247 ADLLPRGEYVEIPDARTLVQLDNPGALCAEL 277 >gi|229820227|ref|YP_002881753.1| alpha/beta hydrolase fold protein [Beutenbergia cavernae DSM 12333] gi|229566140|gb|ACQ79991.1| alpha/beta hydrolase fold protein [Beutenbergia cavernae DSM 12333] Length=280 Score = 144 bits (362), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 103/279 (37%), Positives = 147/279 (53%), Gaps = 12/279 (4%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M TI++ T+ Y +G TG VV +HG ++ +W V +RL G +RC+APT P+GA Sbjct 1 MPTIELETATLDYADSG-GTGPVVVLLHGPLLDHTVWDAVIDRLPG--MRCLAPTLPMGA 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H P P + T +A +VA+ LAAL+L DV LV ND GG +V + ER+G L L Sbjct 58 HRHPA-PHDELTNASLARLVAEFLAALDLTDVTLVLNDWGGAQV-IVELGLAERVGRLAL 115 Query 121 TSCDAFEHFPPPILKPVILAAKSATL---FRAAIQVMRAPAARNRAYAGLSHHNI-DHLT 176 +C+AF++ P +P + A+ A L Q+ R PA R + G++ + D L Sbjct 116 VACEAFDNVP--AGRPGRMLARMARLPGGLALQAQLTRIPAVRRQLATGMAAQPVPDELL 173 Query 177 RAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQ 236 R W P+ +P I +DLR+ S ++ L F PAL+AW+ DD E+G Sbjct 174 RRWFTPS-RDPRIRDDLRRFSARFPIPADRDWSSGLGGFAGPALVAWAEDDRMMPAEHGP 232 Query 237 RLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVR 275 RLA +P A I GA T +D P LA L T+ R Sbjct 233 RLAQLLPDAELVHISGAATLVPLDQPGVLAHHLRTLVAR 271 >gi|118472544|ref|YP_890971.1| oxidoreductase [Mycobacterium smegmatis str. MC2 155] gi|118173831|gb|ABK74727.1| oxidoreductase [Mycobacterium smegmatis str. MC2 155] Length=274 Score = 139 bits (351), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 101/273 (37%), Positives = 142/273 (53%), Gaps = 8/273 (2%) Query 1 MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGA 60 M I++ +G I YE TG + G +VF HG +M G+ WR+V L G RCI PT P+GA Sbjct 1 MPVIELPSGPIAYEDTGGD-GPVLVFGHGLLMDGRQWRKVIPLLPG--CRCITPTLPMGA 57 Query 61 HPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVL 120 H P+RP AD T GVAGI+AD L AL+LKDV LV ND GG L+ R+G LVL Sbjct 58 HTAPMRPDADLTEQGVAGILADFLDALDLKDVTLVLNDWGG-GQFLITDGRDARIGRLVL 116 Query 121 TSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNR--AYAGLSHHNI-DHLTR 177 SC AF+++PP +P + R ++ R+ AY LS + D L Sbjct 117 ASCTAFDNYPPAPARPAAALCRLPGGGRLLTKMFGTRFFRHSRLAYGALSKAGLPDGLFD 176 Query 178 AWVRPALSNPAIAEDLRQLSLSL-RTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQ 236 W RPA+ N A+ DL + + ++ RL F +P L+ W+ +D L++ Sbjct 177 EWFRPAVENAAVRRDLVKFATGAPPRRRLLELSERLRTFTRPVLVVWAREDRMMPLDHAD 236 Query 237 RLAATIPRARFEVIEGARTFSMVDSPDRLADQL 269 RL P A +++ + T D P+ +A L Sbjct 237 RLVELFPDATKVIVDDSWTLIPEDQPEVMAGAL 269 Lambda K H 0.322 0.136 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 435544382258 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40