BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0078
Length=201
Score E
Sequences producing significant alignments: (Bits) Value
gi|308379690|ref|ZP_07669025.1| transcriptional regulator [Mycob... 394 3e-108
gi|15607220|ref|NP_214592.1| transcriptional regulatory protein ... 394 5e-108
gi|31791255|ref|NP_853748.1| transcriptional regulatory protein ... 393 8e-108
gi|183980257|ref|YP_001848548.1| transcriptional regulatory prot... 366 1e-99
gi|118619923|ref|YP_908255.1| transcriptional regulatory protein... 359 1e-97
gi|296167207|ref|ZP_06849613.1| TetR family transcriptional regu... 353 9e-96
gi|41410389|ref|NP_963225.1| hypothetical protein MAP4291c [Myco... 341 3e-92
gi|240168830|ref|ZP_04747489.1| transcriptional regulatory prote... 340 7e-92
gi|342862288|ref|ZP_08718929.1| TetR family transcriptional regu... 329 1e-88
gi|254819454|ref|ZP_05224455.1| transcriptional regulator, TetR ... 324 4e-87
gi|15828443|ref|NP_302706.1| TetR family transcriptional regulat... 238 5e-61
gi|312199419|ref|YP_004019480.1| TetR family transcriptional reg... 188 4e-46
gi|284047130|ref|YP_003397470.1| TetR family transcriptional reg... 178 5e-43
gi|296166305|ref|ZP_06848742.1| TetR family transcriptional regu... 168 3e-40
gi|343925820|ref|ZP_08765335.1| putative TetR family transcripti... 168 3e-40
gi|254821617|ref|ZP_05226618.1| TetR family transcriptional regu... 167 6e-40
gi|342857518|ref|ZP_08714174.1| TetR family transcriptional regu... 166 2e-39
gi|108802131|ref|YP_642328.1| TetR family transcriptional regula... 164 9e-39
gi|302529516|ref|ZP_07281858.1| predicted protein [Streptomyces ... 163 1e-38
gi|262200856|ref|YP_003272064.1| TetR family transcriptional reg... 155 2e-36
gi|337769399|emb|CCB78112.1| Transcriptional regulator, TetR fam... 137 1e-30
gi|300787012|ref|YP_003767303.1| TetR family transcriptional reg... 134 6e-30
gi|154252656|ref|YP_001413480.1| TetR family transcriptional reg... 133 1e-29
gi|254774728|ref|ZP_05216244.1| TetR family transcriptional regu... 132 2e-29
gi|342857602|ref|ZP_08714258.1| TetR family transcriptional regu... 130 1e-28
gi|111225522|ref|YP_716316.1| TetR family transcriptional regula... 130 1e-28
gi|336177220|ref|YP_004582595.1| regulatory protein TetR [Franki... 127 9e-28
gi|13472203|ref|NP_103770.1| transcriptional regulator [Mesorhiz... 124 1e-26
gi|118467262|ref|YP_881151.1| TetR family transcriptional regula... 123 2e-26
gi|300743926|ref|ZP_07072946.1| transcriptional regulator, TetR ... 122 3e-26
gi|291449718|ref|ZP_06589108.1| transcriptional regulator [Strep... 122 4e-26
gi|271965954|ref|YP_003340150.1| TetR family transcriptional reg... 121 5e-26
gi|238060747|ref|ZP_04605456.1| TetR family transcriptional regu... 121 7e-26
gi|115522731|ref|YP_779642.1| TetR family transcriptional regula... 119 4e-25
gi|108804645|ref|YP_644582.1| TetR family transcriptional regula... 118 5e-25
gi|333920235|ref|YP_004493816.1| TetR family transcriptional reg... 117 9e-25
gi|291299466|ref|YP_003510744.1| TetR family transcriptional reg... 116 2e-24
gi|326444725|ref|ZP_08219459.1| putative TetR family transcripti... 116 2e-24
gi|294816397|ref|ZP_06775040.1| TetR family transcriptional regu... 115 3e-24
gi|324999589|ref|ZP_08120701.1| putative TetR family transcripti... 115 3e-24
gi|312199706|ref|YP_004019767.1| TetR family transcriptional reg... 115 3e-24
gi|197106377|ref|YP_002131754.1| transcriptional regulator, TetR... 115 3e-24
gi|27377507|ref|NP_769036.1| transcriptional regulator [Bradyrhi... 114 1e-23
gi|158317458|ref|YP_001509966.1| TetR family transcriptional reg... 114 1e-23
gi|300784077|ref|YP_003764368.1| TetR family transcriptional reg... 114 1e-23
gi|134098215|ref|YP_001103876.1| putative TetR-type transcriptio... 113 2e-23
gi|118588644|ref|ZP_01546052.1| possible transcriptional regulat... 112 2e-23
gi|291004364|ref|ZP_06562337.1| putative TetR-type transcription... 111 5e-23
gi|288920424|ref|ZP_06414733.1| transcriptional regulator, TetR ... 111 6e-23
gi|257055095|ref|YP_003132927.1| transcriptional regulator [Sacc... 110 1e-22
>gi|308379690|ref|ZP_07669025.1| transcriptional regulator [Mycobacterium tuberculosis SUMu010]
gi|308356196|gb|EFP45047.1| transcriptional regulator [Mycobacterium tuberculosis SUMu010]
Length=227
Score = 394 bits (1013), Expect = 3e-108, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA
Sbjct 27 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 86
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV
Sbjct 87 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 146
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP
Sbjct 147 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 206
Query 181 KRARRETRQVLRRLIDGMLNG 201
KRARRETRQVLRRLIDGMLNG
Sbjct 207 KRARRETRQVLRRLIDGMLNG 227
>gi|15607220|ref|NP_214592.1| transcriptional regulatory protein [Mycobacterium tuberculosis
H37Rv]
gi|15839457|ref|NP_334494.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|148659838|ref|YP_001281361.1| putative transcriptional regulatory protein [Mycobacterium tuberculosis
H37Ra]
69 more sequence titles
Length=201
Score = 394 bits (1011), Expect = 5e-108, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA
Sbjct 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV
Sbjct 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP
Sbjct 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLNG 201
KRARRETRQVLRRLIDGMLNG
Sbjct 181 KRARRETRQVLRRLIDGMLNG 201
>gi|31791255|ref|NP_853748.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97]
gi|121635989|ref|YP_976212.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224988462|ref|YP_002643149.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|31616840|emb|CAD92942.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN [Mycobacterium bovis
AF2122/97]
gi|121491636|emb|CAL70094.1| Probable transcriptional regulatory protein [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224771575|dbj|BAH24381.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|341600005|emb|CCC62673.1| probable transcriptional regulatory protein [Mycobacterium bovis
BCG str. Moreau RDJ]
Length=201
Score = 393 bits (1009), Expect = 8e-108, Method: Compositional matrix adjust.
Identities = 200/201 (99%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA
Sbjct 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQL+LLDAPVV
Sbjct 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLVLLDAPVV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP
Sbjct 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLNG 201
KRARRETRQVLRRLIDGMLNG
Sbjct 181 KRARRETRQVLRRLIDGMLNG 201
>gi|183980257|ref|YP_001848548.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183173583|gb|ACC38693.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=201
Score = 366 bits (940), Expect = 1e-99, Method: Compositional matrix adjust.
Identities = 187/200 (94%), Positives = 189/200 (95%), Gaps = 0/200 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
MEIKRRTQEERSAATREALIT ARKLWG RGYAEVGTPEIA EAGVTRGAMYHQFADKAA
Sbjct 1 MEIKRRTQEERSAATREALITAARKLWGSRGYAEVGTPEIAAEAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LF +VVE VEQDVM RMAT VAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAP V
Sbjct 61 LFGEVVEAVEQDVMTRMATSVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPAV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGFRDVAQRYSLGMTEQLITEAIRAGQL R PVRPLA VLIGALDEAAMFIATADDP
Sbjct 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLN 200
KRARRE+RQVLRRLIDGMLN
Sbjct 181 KRARRESRQVLRRLIDGMLN 200
>gi|118619923|ref|YP_908255.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|118572033|gb|ABL06784.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
Length=201
Score = 359 bits (921), Expect = 1e-97, Method: Compositional matrix adjust.
Identities = 183/200 (92%), Positives = 185/200 (93%), Gaps = 0/200 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME KRRTQEERSAATREALIT ARKLWG RGYAEVGTPEIA EAGVTRGAMYHQFADKAA
Sbjct 1 MESKRRTQEERSAATREALITAARKLWGSRGYAEVGTPEIAAEAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LF +VVE VEQDVM RMAT V SGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAP V
Sbjct 61 LFGEVVEAVEQDVMTRMATSVTTSGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPAV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGF DVAQRYSLGMTEQLITEAIRAGQL R PVRPLA VLIGALDEAAMFIATADDP
Sbjct 121 LGWAGFCDVAQRYSLGMTEQLITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLN 200
KRARRE+RQVLRRLIDGMLN
Sbjct 181 KRARRESRQVLRRLIDGMLN 200
>gi|296167207|ref|ZP_06849613.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295897448|gb|EFG77048.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=202
Score = 353 bits (905), Expect = 9e-96, Method: Compositional matrix adjust.
Identities = 178/201 (89%), Positives = 186/201 (93%), Gaps = 0/201 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME KRRTQEERSAATR+ALI ARKLWGLRGYAEVGTPEIAT AGVTRGAMYHQFADKA
Sbjct 1 MESKRRTQEERSAATRDALIAAARKLWGLRGYAEVGTPEIATAAGVTRGAMYHQFADKAT 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFR+VVE VEQDVMARM TLVAASGA TPADAIRAAVDAWL+VSGDPEVRQL+LLDAP V
Sbjct 61 LFREVVEAVEQDVMARMGTLVAASGATTPADAIRAAVDAWLDVSGDPEVRQLMLLDAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGFRDVAQRYSLGMTEQLITEAIR GQLA+QPVRPLA VLIGALDEAAM IATA+DP
Sbjct 121 LGWAGFRDVAQRYSLGMTEQLITEAIRVGQLAKQPVRPLAHVLIGALDEAAMLIATAEDP 180
Query 181 KRARRETRQVLRRLIDGMLNG 201
+R RR+TRQVL RLIDGML G
Sbjct 181 RRMRRDTRQVLHRLIDGMLAG 201
>gi|41410389|ref|NP_963225.1| hypothetical protein MAP4291c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|118466794|ref|YP_884366.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|254777599|ref|ZP_05219115.1| transcriptional regulator, TetR family protein [Mycobacterium
avium subsp. avium ATCC 25291]
gi|41399223|gb|AAS06841.1| hypothetical protein MAP_4291c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|118168081|gb|ABK68978.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
gi|336459833|gb|EGO38746.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=202
Score = 341 bits (875), Expect = 3e-92, Method: Compositional matrix adjust.
Identities = 173/201 (87%), Positives = 181/201 (91%), Gaps = 0/201 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME KRRTQEERSAATR+ALI ARKLWGLRGY EVGTPEIA AGVTRGAMYHQFADKAA
Sbjct 1 MESKRRTQEERSAATRDALIAAARKLWGLRGYTEVGTPEIAAAAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFR VVE VEQDVMARMA +VA SGA+TP DAIRAAVDAWLEVS DPEVRQLILLDAP V
Sbjct 61 LFRAVVEAVEQDVMARMAVVVAESGASTPTDAIRAAVDAWLEVSADPEVRQLILLDAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWA FRDVAQRYSLGMTEQL+TEAIRAG+LA QPVRPLA VLIGALDEAAM IATADDP
Sbjct 121 LGWAEFRDVAQRYSLGMTEQLLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLNG 201
RARRETRQVL+RL+DGM +
Sbjct 181 DRARRETRQVLQRLVDGMFDA 201
>gi|240168830|ref|ZP_04747489.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=201
Score = 340 bits (872), Expect = 7e-92, Method: Compositional matrix adjust.
Identities = 174/200 (87%), Positives = 183/200 (92%), Gaps = 0/200 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
MEIKRRTQEERSAATREALI+ AR LWG RGYAEVGTPEIA +AGVTRGAMYHQFADKAA
Sbjct 1 MEIKRRTQEERSAATREALISAARTLWGARGYAEVGTPEIAKQAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFRDVVE VE DVMARMATLVAASGA TPADAIRAAVDAWL+VSGDPEVRQLILLDAP V
Sbjct 61 LFRDVVEAVEHDVMARMATLVAASGATTPADAIRAAVDAWLDVSGDPEVRQLILLDAPAV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGW+ FRDVAQRYSLGMTEQL+TEAIRAGQLA PVRPLA V+IGALDEAAM IATA+D
Sbjct 121 LGWSAFRDVAQRYSLGMTEQLLTEAIRAGQLAALPVRPLATVMIGALDEAAMAIATAEDQ 180
Query 181 KRARRETRQVLRRLIDGMLN 200
+RARRE QVLRRLIDG+L
Sbjct 181 QRARREIGQVLRRLIDGLLE 200
>gi|342862288|ref|ZP_08718929.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342130145|gb|EGT83473.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=202
Score = 329 bits (843), Expect = 1e-88, Method: Compositional matrix adjust.
Identities = 172/200 (86%), Positives = 184/200 (92%), Gaps = 0/200 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME KRRTQEERSAATR+ALI ARKLWGLRGYA+VGTPEIAT AGVTRGAMYHQFADKAA
Sbjct 1 MESKRRTQEERSAATRDALIAAARKLWGLRGYADVGTPEIATAAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFR+VVEVVEQDVMARMA +VA SGA+TP DA+RAAVDAWL+VSGDPEVRQLILLDAP V
Sbjct 61 LFREVVEVVEQDVMARMAVVVAESGASTPTDAVRAAVDAWLDVSGDPEVRQLILLDAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWA FRDVAQRYSLGMTEQ++TEAIRAG+LA QPVRPLA VLIGALDEAAM IATADDP
Sbjct 121 LGWAEFRDVAQRYSLGMTEQMLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLN 200
KR+RRET QVL RLID M +
Sbjct 181 KRSRRETGQVLHRLIDAMFD 200
>gi|254819454|ref|ZP_05224455.1| transcriptional regulator, TetR family protein [Mycobacterium
intracellulare ATCC 13950]
Length=202
Score = 324 bits (831), Expect = 4e-87, Method: Compositional matrix adjust.
Identities = 170/200 (85%), Positives = 180/200 (90%), Gaps = 0/200 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME KRRTQEERSAATREALI ARKLWGLRGYA+VGTPEIA+ AGVTRGAMYHQFADKAA
Sbjct 1 MESKRRTQEERSAATREALIAAARKLWGLRGYADVGTPEIASAAGVTRGAMYHQFADKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFR+VVEVVE DVMARMA +VA SGAATP A+R AVDAWLEVS DPEVRQLILLDAP V
Sbjct 61 LFREVVEVVEHDVMARMAVVVAESGAATPTAAVRGAVDAWLEVSADPEVRQLILLDAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWAGFRDVAQRYSLGMTEQ++TEAIRAG+LA QPVRPLA VLIGALDEAAM IATADDP
Sbjct 121 LGWAGFRDVAQRYSLGMTEQMLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATADDP 180
Query 181 KRARRETRQVLRRLIDGMLN 200
R R ETR+VL RLIDGM +
Sbjct 181 DRTRDETREVLHRLIDGMFD 200
>gi|15828443|ref|NP_302706.1| TetR family transcriptional regulator [Mycobacterium leprae TN]
gi|221230920|ref|YP_002504336.1| putative TetR-family transcriptional regulator [Mycobacterium
leprae Br4923]
gi|2959402|emb|CAA17943.1| hypothetical protein MLCB1913.11 [Mycobacterium leprae]
gi|13093873|emb|CAC32209.1| putative TetR-family transcriptional regulator [Mycobacterium
leprae]
gi|219934027|emb|CAR72777.1| putative TetR-family transcriptional regulator [Mycobacterium
leprae Br4923]
Length=236
Score = 238 bits (606), Expect = 5e-61, Method: Compositional matrix adjust.
Identities = 125/175 (72%), Positives = 139/175 (80%), Gaps = 5/175 (2%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME +RRTQEERS ATR+AL +LW LRGYAEVGTPEIA EA TRGA+YHQF DKAA
Sbjct 1 MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFRDVVE VEQD MA++A++VA+SGA TP DAIRA VDAWLE DP+VRQLILL AP V
Sbjct 61 LFRDVVETVEQDAMAQIASVVASSGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTE-QLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFI 174
LGWA FRDVAQ YSLGMTE QL++EA RA QLA +PL VLIG L E+AM I
Sbjct 121 LGWAAFRDVAQHYSLGMTEQQLLSEASRARQLA----QPLDHVLIGKLYESAMAI 171
>gi|312199419|ref|YP_004019480.1| TetR family transcriptional regulator [Frankia sp. EuI1c]
gi|311230755|gb|ADP83610.1| regulatory protein TetR [Frankia sp. EuI1c]
Length=209
Score = 188 bits (478), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 98/194 (51%), Positives = 131/194 (68%), Gaps = 0/194 (0%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RR Q +RSA TR AL+ R+L+ G+A V T I T AGV+RGA+YHQFADK ALF
Sbjct 14 RRRQVDRSATTRAALVAAGRRLFAAEGFAAVATESIVTAAGVSRGALYHQFADKTALFAA 73
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
VVE VE DV AR+A VAA+G+ P +A+R A D WL + +PEV +++LLD P VLGWA
Sbjct 74 VVEAVEADVAARIADEVAAAGSTDPIEAMRLAADTWLRICVEPEVHRIVLLDGPSVLGWA 133
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R++ QR+ G+ ++ + G++ RQPV PLA VL+GA DEAA++IA A D + AR
Sbjct 134 EWRELCQRHVFGLVRDVLVWGMEIGRIRRQPVDPLAHVLMGASDEAALYIARAPDTETAR 193
Query 185 RETRQVLRRLIDGM 198
E L +IDG+
Sbjct 194 TEMINALGLVIDGL 207
>gi|284047130|ref|YP_003397470.1| TetR family transcriptional regulator [Conexibacter woesei DSM
14684]
gi|283951351|gb|ADB54095.1| transcriptional regulator, TetR family [Conexibacter woesei DSM
14684]
Length=211
Score = 178 bits (451), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 101/195 (52%), Positives = 132/195 (68%), Gaps = 2/195 (1%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
M +KRRTQ ERS++TR AL+ AR L+ +G+A VGT I AGVTRGA+YHQFADK
Sbjct 1 MSVKRRTQRERSSSTRTALLAAARPLFAEQGFAAVGTEAIVRAAGVTRGALYHQFADKTE 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LF V E VE+DV+ R+ +A G A P + A V+AWL+ DP V+Q++L+DAP V
Sbjct 61 LFVAVFEQVERDVVERIGAQLA--GLADPGAVLEAGVEAWLDACEDPAVQQIVLIDAPAV 118
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGW +R + Q Y G+ E I +I AG++ QPVRPLA VLIGALDEAA+++A A+D
Sbjct 119 LGWERWRALGQTYGGGLVEAAIAASIEAGRIRPQPVRPLAHVLIGALDEAALYVARAEDR 178
Query 181 KRARRETRQVLRRLI 195
AR E VLR ++
Sbjct 179 ASARVEMSAVLRGIV 193
>gi|296166305|ref|ZP_06848742.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295898314|gb|EFG77883.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=219
Score = 168 bits (426), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 89/191 (47%), Positives = 121/191 (64%), Gaps = 0/191 (0%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ ERSA TREALI+ AR L+ +G++EV I AGVTRGA+YH FADK LF
Sbjct 10 RRTQAERSAETREALISAARPLFAAQGFSEVALEAIVRAAGVTRGALYHHFADKTELFAT 69
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
V E VE +V A M +AASG + +R WLE D E++++ L+DAP VLGWA
Sbjct 70 VFEQVEAEVAAHMGEAIAASGETDAIEVMRLGAAYWLEACSDHEIQRIALVDAPAVLGWA 129
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+ ++ RY+LG+ L++ AI G++ QPV A ++GA+ EA +++A A+D AR
Sbjct 130 RWTEIGNRYNLGLVRALLSGAIETGRIPPQPVEATALTMLGAMREATLYVARAEDHATAR 189
Query 185 RETRQVLRRLI 195
RE V+ RLI
Sbjct 190 REAGAVIDRLI 200
>gi|343925820|ref|ZP_08765335.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
gi|343764171|dbj|GAA12261.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
Length=200
Score = 168 bits (426), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 99/198 (50%), Positives = 131/198 (67%), Gaps = 0/198 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
M++ RRTQ ER+AATR ALI RKL+G RG+A+VGT EI EAGVTRGA+YHQF DK
Sbjct 1 MKVNRRTQAERTAATRAALIAAGRKLFGERGFADVGTQEIVDEAGVTRGALYHQFDDKKG 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LF V + VEQDV+ ++A V A A P A+++ + +LE+ +P V ++ L++AP V
Sbjct 61 LFTAVYDAVEQDVVTQIAEAVGALAADDPIAALKSGMRLFLELCTEPSVHRITLVEAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGWA +R + + + E LI AI AGQ QP RPLA V IGALDEAA+++A A+D
Sbjct 121 LGWAQWRARGEEFGFALVEGLIKAAIAAGQAIDQPTRPLAHVAIGALDEAALYVAAAEDR 180
Query 181 KRARRETRQVLRRLIDGM 198
A E VL R++D
Sbjct 181 DAATAEVAAVLDRIVDSF 198
>gi|254821617|ref|ZP_05226618.1| TetR family transcriptional regulator [Mycobacterium intracellulare
ATCC 13950]
Length=205
Score = 167 bits (424), Expect = 6e-40, Method: Compositional matrix adjust.
Identities = 86/194 (45%), Positives = 121/194 (63%), Gaps = 0/194 (0%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ ER+A TREAL+ AR L+ G+A+ I AGVTRGA+YH FADK LF
Sbjct 6 RRTQAERAAGTREALVAAARPLFASLGFADASLETIVRNAGVTRGALYHHFADKTELFAA 65
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
V E VE ++ ARM VAA+G P + +R WL+ DPE+++++LL+A VLGW
Sbjct 66 VFEQVEGEMAARMGDAVAAAGHGDPVEIMRLCAALWLDACADPEIQRIVLLEALAVLGWE 125
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+ + RY++G L+TEAI +G + RQP+ A ++GAL EA ++IA ADD +AR
Sbjct 126 RWSAIGHRYNIGFVTALLTEAIESGSIPRQPIEATALTIMGALREATLYIARADDYHQAR 185
Query 185 RETRQVLRRLIDGM 198
+ V+ RL+ +
Sbjct 186 ADAGVVMDRLLSAL 199
>gi|342857518|ref|ZP_08714174.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342134851|gb|EGT88017.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=205
Score = 166 bits (420), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 85/194 (44%), Positives = 125/194 (65%), Gaps = 0/194 (0%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ ER+A TR+ALI AR L+ G+A+ I +AGVTRGA+YH FADK LF
Sbjct 6 RRTQAERAAETRDALIGAARPLFASVGFADASLETIVRDAGVTRGALYHHFADKTELFAA 65
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
V E VE ++ ARM VAA+G + P + +R WL+ +PE+++++LL+A VLGW
Sbjct 66 VFEQVEGEMAARMGEAVAAAGHSDPVEIMRLCSGLWLDACAEPEIQRIVLLEALAVLGWE 125
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+ D+ RY++G L+ +AI +G + RQPV A ++GAL EA ++IA ADD ++AR
Sbjct 126 RWSDIGHRYNIGFVTGLLADAIESGSIPRQPVEATALTIMGALREATLYIARADDQRQAR 185
Query 185 RETRQVLRRLIDGM 198
+ V+ RL++ +
Sbjct 186 ADAGAVMDRLLEAL 199
>gi|108802131|ref|YP_642328.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
gi|119871284|ref|YP_941236.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|126438112|ref|YP_001073803.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
gi|108772550|gb|ABG11272.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
gi|119697373|gb|ABL94446.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
gi|126237912|gb|ABO01313.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=215
Score = 164 bits (414), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 85/194 (44%), Positives = 127/194 (66%), Gaps = 0/194 (0%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ +R+A TR L+ R+L+ + + +V T I AGVTRGA+YHQFADK+ALF
Sbjct 14 RRTQAQRTAETRSRLVAAGRRLFAQQPFTDVSTQAIVEAAGVTRGALYHQFADKSALFEA 73
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
V E VEQ+++A +A + A A+ A+RA +LE P++ ++ L++AP VLGW
Sbjct 74 VYEEVEQELVAEIAGAIEAGEASDHLAAMRAGARLFLERCASPDIHRIALVNAPAVLGWE 133
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R++ Y LG+ E ++ +AI G + QPVRP A +++GALDEAA++I+ A+D ++A
Sbjct 134 RWREIGAHYGLGVIEAMLAQAIADGAIPEQPVRPTAHMVLGALDEAALYISRAEDAEQAL 193
Query 185 RETRQVLRRLIDGM 198
E V RLIDG+
Sbjct 194 VEMYAVCDRLIDGI 207
>gi|302529516|ref|ZP_07281858.1| predicted protein [Streptomyces sp. AA4]
gi|302438411|gb|EFL10227.1| predicted protein [Streptomyces sp. AA4]
Length=197
Score = 163 bits (413), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 90/195 (47%), Positives = 124/195 (64%), Gaps = 2/195 (1%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ+ERS ATR ALI AR L+G RGY +V EI AGVTRGA+YH F DK LFR
Sbjct 2 RRTQQERSDATRAALIKAARDLFGARGYHDVPAEEITRTAGVTRGALYHHFGDKQGLFRA 61
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
VVEV+E+++ A ++ ++ GAA P + +A+ +L+ P+VR++ L DAP VLGW
Sbjct 62 VVEVLERELTAEVSAVL--DGAADPLSGLSSALGVFLDACLRPDVRRISLTDAPAVLGWD 119
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+RD+ Y LG+ + + A AG + PV LAQ+++ A+ EAA IA ADDP R R
Sbjct 120 AWRDLEAEYGLGLVAENLAAAREAGLIVDTPVDALAQLVLAAVMEAARMIANADDPDRVR 179
Query 185 RETRQVLRRLIDGML 199
+ +QV + G+L
Sbjct 180 GDVQQVFSGWLSGLL 194
>gi|262200856|ref|YP_003272064.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262084203|gb|ACY20171.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=201
Score = 155 bits (393), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 90/198 (46%), Positives = 125/198 (64%), Gaps = 0/198 (0%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
M++ RRTQ ER+AATR ALI R+L+G GYA VGT I AGVTRGA+YHQF DK
Sbjct 1 MKVNRRTQAERTAATRAALIGAGRELFGEHGYASVGTQVIVEAAGVTRGALYHQFGDKKG 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LF V + +EQ+V+A A + P A++ + A+LEV DP ++ L+DAP V
Sbjct 61 LFTAVFDALEQEVVALCADAMTDLAPTDPIAALKVGIRAFLEVFTDPVRHRIGLVDAPSV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGW +R + + + E L+ +I GQ+A QP+RP+A V IGALDE+A+++A A D
Sbjct 121 LGWQEWRARGEEFGFALIEGLLQASIELGQMADQPIRPIAHVAIGALDESALYVAAAADR 180
Query 181 KRARRETRQVLRRLIDGM 198
++A E VL R++D
Sbjct 181 QQAVAEVTVVLDRIVDSF 198
>gi|337769399|emb|CCB78112.1| Transcriptional regulator, TetR family [Streptomyces cattleya
NRRL 8057]
Length=211
Score = 137 bits (344), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 75/192 (40%), Positives = 115/192 (60%), Gaps = 3/192 (1%)
Query 10 ERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVV 69
E TR AL++ AR+L+ RGYA GT +I T A VTRGA+YH F DKA LFR V+
Sbjct 13 EHVTDTRRALLSAARRLFADRGYAATGTEDIVTAARVTRGALYHHFRDKADLFRAVMAEC 72
Query 70 EQDVMARMATLVAASGAATPADA---IRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGF 126
Q++ R+ P DA +R ++L+ DP+ ++++L++ P VLG + +
Sbjct 73 AQEMAERLVEQEVRRAEEHPGDAWQLLRTGFQSFLDACTDPDFQRIVLIEGPAVLGHSAW 132
Query 127 RDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRE 186
+ +R+ G+ + +TEAI G++ PVRPL ++L + EA+++IA ADD + ARRE
Sbjct 133 DALVERHGYGLLAEALTEAIAEGRVDPLPVRPLTRMLAALISEASLYIARADDHEEARRE 192
Query 187 TRQVLRRLIDGM 198
VL RL+ G+
Sbjct 193 AGAVLDRLLTGL 204
>gi|300787012|ref|YP_003767303.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|299796526|gb|ADJ46901.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|340528504|gb|AEK43709.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
S699]
Length=196
Score = 134 bits (338), Expect = 6e-30, Method: Compositional matrix adjust.
Identities = 83/195 (43%), Positives = 117/195 (60%), Gaps = 2/195 (1%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ++RSA T+ AL+ AR+L+ RGY V EI AGVTRGA+YH +ADK LFR
Sbjct 2 RRTQQDRSAGTKAALVAAARELFAARGYQAVPAEEITRAAGVTRGALYHHYADKQGLFRA 61
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
VVE +E+++ + AA A P + + +L+ EVR++ L DAP VLGW
Sbjct 62 VVEELERELTEEVRAAFAAG--ADPLAGMLQGLGVFLDACLREEVRRISLTDAPAVLGWD 119
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R++ Y LG+ ++T+A G + PV LAQ+++ A+ EAA IA ADDP R R
Sbjct 120 VWREIEAEYGLGLIVAVLTQARADGLIVELPVHALAQLMLSAVMEAARMIAAADDPARTR 179
Query 185 RETRQVLRRLIDGML 199
E +QVL + +L
Sbjct 180 AEVQQVLGAWLGSLL 194
>gi|154252656|ref|YP_001413480.1| TetR family transcriptional regulator [Parvibaculum lavamentivorans
DS-1]
gi|154156606|gb|ABS63823.1| transcriptional regulator, TetR family [Parvibaculum lavamentivorans
DS-1]
Length=205
Score = 133 bits (335), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 77/206 (38%), Positives = 113/206 (55%), Gaps = 17/206 (8%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
M + R ++ + RE L+ AR+L+GLRGY EVGT EI EAGVTRGA+Y+QFADK
Sbjct 3 MPVSRSAPAKKPSKNREQLLAAARRLFGLRGYGEVGTEEIVREAGVTRGALYYQFADKQD 62
Query 61 LFR--------DVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQL 112
LFR ++ V ++ MAR+ + + L+V EV+Q+
Sbjct 63 LFRALFISMLHEIGHEVFEETMARV---------THDTEDLMVGTQMLLDVYSRAEVKQI 113
Query 113 ILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAM 172
+L+D P VLGW +RD+ + M + + G LA QP+ P+A ++ GAL +A +
Sbjct 114 VLIDGPAVLGWNEWRDLQEPLHQAMLTHALQHLVDEGWLAPQPLEPVASLIAGALMQAGL 173
Query 173 FIATADDPKRARRETRQVLRRLIDGM 198
IA ADDP AR+ + L L++G
Sbjct 174 AIANADDPAEARKIYGRGLETLVEGF 199
>gi|254774728|ref|ZP_05216244.1| TetR family transcriptional regulator [Mycobacterium avium subsp.
avium ATCC 25291]
Length=159
Score = 132 bits (333), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 65/153 (43%), Positives = 96/153 (63%), Gaps = 0/153 (0%)
Query 46 VTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSG 105
+TRGA+YH FADK LF V E VE ++ ARM VAA+G P + +R WL+
Sbjct 1 MTRGALYHHFADKTELFAAVFEQVEGEMAARMGDAVAAAGHGDPVEIMRLCAALWLDACA 60
Query 106 DPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIG 165
DPE+++++LL+A VLGW + + RY++G L+TEAI +G + RQP+ A ++G
Sbjct 61 DPEIQRIVLLEALAVLGWERWSAIGHRYNIGFVTALLTEAIESGSIPRQPIEATALTIMG 120
Query 166 ALDEAAMFIATADDPKRARRETRQVLRRLIDGM 198
AL EA ++IA ADD +AR + V+ RL+ +
Sbjct 121 ALREATLYIARADDYHQARADAGVVMDRLLSAL 153
>gi|342857602|ref|ZP_08714258.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342134935|gb|EGT88101.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=210
Score = 130 bits (327), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 70/178 (40%), Positives = 109/178 (62%), Gaps = 3/178 (1%)
Query 19 LITGARKLWGLRGYAEVGTPEIATEAGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARM 77
LI R+L+ RG+ ++ T++GV TRGA YH F DKA LFR V E VE D+ R
Sbjct 22 LIEAGRELFVERGFFNTSIGDLVTKSGVGTRGAFYHHFKDKAELFRAVFEDVENDLTLR- 80
Query 78 ATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGM 137
++ A A P + + + + +LE + +P V++++L+D PVVLGW R++ + S+ +
Sbjct 81 -SIAAPPPGADPWERLTSGLHGFLEAATEPAVQRVMLIDGPVVLGWQTLREIQENNSIAL 139
Query 138 TEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLI 195
++ EAI AG + QPV L +L+ AL+EAA+ +A A +P +ARR +VL RL+
Sbjct 140 INDVVREAIAAGIIDDQPVGELTHMLVAALEEAALLVAHAANPTKARRRAAKVLDRLL 197
>gi|111225522|ref|YP_716316.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111153054|emb|CAJ64801.1| putative TetR family transcriptional regulatory protein [Frankia
alni ACN14a]
Length=210
Score = 130 bits (326), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 68/170 (40%), Positives = 102/170 (60%), Gaps = 0/170 (0%)
Query 10 ERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVV 69
ER AATRE L+ A +L+ RGY + TE GV+RG++YH F K ALF V+E V
Sbjct 18 ERGAATREHLLGVATRLFAERGYEGTSIDAVLTETGVSRGSLYHHFKGKDALFDAVLEAV 77
Query 70 EQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDV 129
E DV R+ V + PA A+R AW+ ++GDP V++++L+DAP VLGWA +R++
Sbjct 78 ELDVGRRLVAAVGTDSSRDPATALRLGCMAWIGIAGDPVVQRILLIDAPGVLGWARWREL 137
Query 130 AQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADD 179
+R++ G +Q + E R G A VL+ +++E A+ +A AD+
Sbjct 138 DERHAFGKIKQTVAELARDGVFDASMADLFAHVLLASMNEIALLVARADN 187
>gi|336177220|ref|YP_004582595.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
gi|334858200|gb|AEH08674.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata]
Length=213
Score = 127 bits (319), Expect = 9e-28, Method: Compositional matrix adjust.
Identities = 77/193 (40%), Positives = 115/193 (60%), Gaps = 4/193 (2%)
Query 10 ERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVV 69
E AATR+AL+ AR +G +GYA GT EI +A VTRGA+YH F DKA LF V+E V
Sbjct 8 EHPAATRQALMAAARLRFGTQGYAATGTEEIVADAQVTRGALYHHFRDKADLFGAVMEQV 67
Query 70 EQDVMARMATLV---AASGAATPA-DAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAG 125
+V ++ T A + T A + +RA ++L++ D + ++++L+D P VLG
Sbjct 68 ALEVAEQLVTTELKRATDESDTDAWEQLRAGFQSFLDICTDSDFQRIVLVDGPAVLGHDA 127
Query 126 FRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARR 185
+ + +RY + + +T AI G++ PV PL +VL L EA++ I A DP +ARR
Sbjct 128 WDVLVERYGYRLLAEWLTRAIEEGRIDPLPVMPLTRVLAAVLSEASLLIGRAGDPAQARR 187
Query 186 ETRQVLRRLIDGM 198
E +VL RL+ G+
Sbjct 188 EAGEVLDRLLVGL 200
>gi|13472203|ref|NP_103770.1| transcriptional regulator [Mesorhizobium loti MAFF303099]
gi|14022948|dbj|BAB49556.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]
Length=208
Score = 124 bits (310), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 86/201 (43%), Positives = 111/201 (56%), Gaps = 14/201 (6%)
Query 2 EIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAAL 61
E RR+ +R+ ATR LI ARKL+ + YAE GTPEI T AGVTRGA+YH FADK AL
Sbjct 4 ESARRSNRDRTEATRADLIAAARKLFTEKSYAETGTPEIVTAAGVTRGALYHHFADKQAL 63
Query 62 FRDVVEVVEQDVMARMATLVAASGAATPA-DAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
F VVEQ+ A + AS ++ A DA+ A DA+L+ P +L+LLD P V
Sbjct 64 F---AAVVEQEAQAVAQEIERASPSSLEARDALIAGSDAYLDAMRAPGRTRLLLLDGPAV 120
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFI---ATA 177
LG A + R+ + + A+RA + R PV L +L A D AA+ I A+A
Sbjct 121 LGRAAMDAIDNRHGNRSLREGLVAAMRANTMTRLPVDALTALLASAFDRAALAIEAGASA 180
Query 178 DDPKRARRETRQVLRRLIDGM 198
D R VL LIDG+
Sbjct 181 QD-------YRAVLMALIDGL 194
>gi|118467262|ref|YP_881151.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118168549|gb|ABK69446.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=211
Score = 123 bits (308), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 80/198 (41%), Positives = 118/198 (60%), Gaps = 10/198 (5%)
Query 6 RTQE--ERSAATREALITGARKLWGLRGYAEVGTPEIATEAGV-TRGAMYHQFADKAALF 62
RT E +R+ ATR ALI R+L+ +GY GT EI AGV TRGA+YH FA+K ALF
Sbjct 15 RTAEIADRAEATRAALIAAGRRLFVEKGYFATGTEEIVAAAGVGTRGALYHHFANKEALF 74
Query 63 RDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLG 122
V V++ V ++ A A+RA + A+L+ S EV+++++++ P VLG
Sbjct 75 LAVFLAVQEQVDSQAPRPEYTEDAL---GALRAGLRAYLKSSLTGEVQRILMIEGPAVLG 131
Query 123 WAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKR 182
W +R++ ++ LG L+ +A+ G + QP+ LA VL+ A DEAA F+A A DP++
Sbjct 132 WQRWRELQVQFGLGSIRALLEKAVEQGAVTPQPLDVLAHVLLAAADEAARFVANASDPQQ 191
Query 183 ARRETRQVLRRLIDGMLN 200
AR + QV IDG+L
Sbjct 192 ARDDAIQV----IDGILQ 205
>gi|300743926|ref|ZP_07072946.1| transcriptional regulator, TetR family [Rothia dentocariosa M567]
gi|300380287|gb|EFJ76850.1| transcriptional regulator, TetR family [Rothia dentocariosa M567]
Length=196
Score = 122 bits (305), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 72/198 (37%), Positives = 116/198 (59%), Gaps = 6/198 (3%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
ME +R Q E AT AL+T AR+ + GY V +I + G+T+GA+YH F +K
Sbjct 1 MEGQRAAQRE---ATVSALVTEARQRFARDGYTSVRIDDIVSSLGITKGALYHHFKNKKD 57
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFR VV V+QDV ++ AA ATP + + ++ S +P VR+++L+DAP V
Sbjct 58 LFRAVVCEVQQDVGYQIED--AARSCATPWEELVEGSKTFILASIEPNVRRIMLVDAPAV 115
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LGW +R + + S+ + ++ + +A+QPV PL+ +L GA++EAA+++A D P
Sbjct 116 LGWHEWRALDESSSMVLLADILKTLMEQEIIAKQPVEPLSHLLSGAMNEAALWLAETDSP 175
Query 181 KRARRETRQVLRRLIDGM 198
A +T + L RL++ +
Sbjct 176 D-ALEDTMKTLTRLLESL 192
>gi|291449718|ref|ZP_06589108.1| transcriptional regulator [Streptomyces albus J1074]
gi|291352667|gb|EFE79569.1| transcriptional regulator [Streptomyces albus J1074]
Length=216
Score = 122 bits (305), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 64/166 (39%), Positives = 103/166 (63%), Gaps = 2/166 (1%)
Query 15 TREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVM 74
TR+AL+ +R+L+ GY VG EI AGVT+GA+YH F+ KA LFR V+E +Q+V
Sbjct 33 TRQALVRESRRLFSTLGYGAVGLSEIVAAAGVTKGALYHHFSSKAELFRVVLEQAQQEVA 92
Query 75 ARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYS 134
R+A A ++ + + +A+L S DP +++++L+D P VLGWA +R++ + S
Sbjct 93 ERIAATADARDSSW--EQLLVGCEAFLGASTDPAIQRIMLIDGPAVLGWAEWREMNEATS 150
Query 135 LGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
+++ I G + QPV PL +L GA++EAA+++A + DP
Sbjct 151 GRHLAEVLAVLIEEGTIPAQPVEPLTHLLSGAMNEAALWLAASSDP 196
>gi|271965954|ref|YP_003340150.1| TetR family transcriptional regulator [Streptosporangium roseum
DSM 43021]
gi|270509129|gb|ACZ87407.1| putative transcriptional regulator, TetR family [Streptosporangium
roseum DSM 43021]
Length=205
Score = 121 bits (304), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 72/175 (42%), Positives = 108/175 (62%), Gaps = 2/175 (1%)
Query 6 RTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDV 65
R++ ++ TR AL+ R+L+ RGY V EI A +T+GA+YH F K ALFR V
Sbjct 6 RSKAQQRLETRRALVAEGRRLFARRGYGAVSLAEIVENAEMTKGALYHHFDSKTALFRTV 65
Query 66 VEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAG 125
VE V+Q+V AR+A+ A P + + A A+L S DPEV+Q++L+D P VLGW
Sbjct 66 VEQVQQEVAARVASAAEARD--DPWEQLIAGCHAFLAASSDPEVQQIMLIDGPAVLGWEE 123
Query 126 FRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
+R + + S + +T + G + RQPV PLA++L GA++EAA+++A + DP
Sbjct 124 WRAMDEDSSARHLTEALTTLVETGIIVRQPVAPLARLLSGAMNEAALWLARSADP 178
>gi|238060747|ref|ZP_04605456.1| TetR family transcriptional regulator [Micromonospora sp. ATCC
39149]
gi|237882558|gb|EEP71386.1| TetR family transcriptional regulator [Micromonospora sp. ATCC
39149]
Length=228
Score = 121 bits (303), Expect = 7e-26, Method: Compositional matrix adjust.
Identities = 77/197 (40%), Positives = 119/197 (61%), Gaps = 6/197 (3%)
Query 2 EIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAAL 61
++R Q E+ TR L+ +R+L+ GY VG +I AGVT+GA+YH FA KA +
Sbjct 35 HMRRAEQREQ---TRHTLVRESRRLFATHGYGAVGLAQIVAAAGVTKGALYHHFAGKADV 91
Query 62 FRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVL 121
FR V+E+V+Q+V A++ A P + A A+L S P+V++++L+D P VL
Sbjct 92 FRAVLELVQQEVAAQVVAAAEAQ--HDPWARLTAGCRAFLTASTAPQVQRIMLVDGPAVL 149
Query 122 GWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPK 181
GWA +R + + S + +T+ I AG +A QPV PLA +L GA++EAA+++AT P
Sbjct 150 GWADWRALDEAASAHHLAEALTDLIAAGTIAAQPVTPLAHLLSGAMNEAALWLATTTSPH 209
Query 182 RARRETRQVLRRLIDGM 198
A +T L RL++G+
Sbjct 210 -ALEQTCTALTRLLEGL 225
>gi|115522731|ref|YP_779642.1| TetR family transcriptional regulator [Rhodopseudomonas palustris
BisA53]
gi|115516678|gb|ABJ04662.1| transcriptional regulator, TetR family [Rhodopseudomonas palustris
BisA53]
Length=196
Score = 119 bits (297), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 79/198 (40%), Positives = 110/198 (56%), Gaps = 7/198 (3%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
+ KRRT + RS T+ ALI AR+ + RGYAE TP++ AGVTRGA+YH FADK A
Sbjct 2 LATKRRTNQARSDTTKTALIAAARQAFIARGYAETSTPDLVEAAGVTRGALYHHFADKEA 61
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LFR VVE EQ +A + A G +P +A+ A +A+L P +L+L+DAP V
Sbjct 62 LFRAVVE-AEQAAVA--GGIEDAPGPGSPVEALIAGGEAYLAAMKAPGRTRLLLIDAPAV 118
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
LG A + R+ + + + AI +G + P+ AQ+L A D AA+ I D
Sbjct 119 LGRAEVDVIDARHGVRTLREGLRAAIESGAIEPLPIEATAQLLGAAYDRAALAIEGGAD- 177
Query 181 KRARRETRQVLRRLIDGM 198
R E LR +I+G+
Sbjct 178 ---RSEFHAALRAMIEGL 192
>gi|108804645|ref|YP_644582.1| TetR family transcriptional regulator [Rubrobacter xylanophilus
DSM 9941]
gi|108765888|gb|ABG04770.1| transcriptional regulator, TetR family [Rubrobacter xylanophilus
DSM 9941]
Length=209
Score = 118 bits (295), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 79/191 (42%), Positives = 113/191 (60%), Gaps = 3/191 (1%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
RRTQ ER AATR AL+ AR+L+ +GY E EI AG+TRGA+YH F DK LFR
Sbjct 10 RRTQAERRAATRRALLDAARELFAEKGYHETSAEEIVRRAGLTRGALYHHFEDKRDLFRV 69
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
VV+ E + A A +A+ A A+++ DPE+++ LD P VLGW
Sbjct 70 VVD--EMESEIDEEIEAAERAEAELPEAVMAGYRAFVDAVLDPEMKRTFFLDGPSVLGWE 127
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R++ R+++G E+ + I G + QPV PLA+++ GAL EAA F+A +DDP+ AR
Sbjct 128 -WREIDARHAVGKIEEGLEALIAEGYIEPQPVGPLARLINGALLEAAFFVADSDDPQTAR 186
Query 185 RETRQVLRRLI 195
+ + RL+
Sbjct 187 DQVWGAMERLV 197
>gi|333920235|ref|YP_004493816.1| TetR family transcriptional regulator [Amycolicicoccus subflavus
DQS3-9A1]
gi|333482456|gb|AEF41016.1| TetR family transcriptional regulator [Amycolicicoccus subflavus
DQS3-9A1]
Length=197
Score = 117 bits (293), Expect = 9e-25, Method: Compositional matrix adjust.
Identities = 71/188 (38%), Positives = 109/188 (58%), Gaps = 9/188 (4%)
Query 3 IKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALF 62
+ +RT+ ++ T AL+ AR+L+ RGYA V EIA+ AGVT+G +YH F+ K ALF
Sbjct 1 MPQRTKAQQRDKTARALLGHARQLFAERGYAHVSLNEIASAAGVTKGGLYHHFSGKEALF 60
Query 63 RDVVEVVEQDVMARMATLVAASGAATPADA---IRAAVDAWLEVSGDPEVRQLILLDAPV 119
VV +V A++ + AA ADA + A A+L S +P + Q++L+DAP
Sbjct 61 EAVVHECHLEVAAQIES------AAPDADAWTQLVAGCQAFLTASTEPGLAQIMLIDAPS 114
Query 120 VLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADD 179
V+GW +R S+ E + E + G +A QPV P+A +L GA++EAA+++A + D
Sbjct 115 VIGWHAWRGHDAATSMRQLETALAELMDTGVIASQPVAPIAHLLSGAMNEAALWLAHSGD 174
Query 180 PKRARRET 187
R +T
Sbjct 175 RVRDLSDT 182
>gi|291299466|ref|YP_003510744.1| TetR family transcriptional regulator [Stackebrandtia nassauensis
DSM 44728]
gi|290568686|gb|ADD41651.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis
DSM 44728]
Length=202
Score = 116 bits (290), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 74/191 (39%), Positives = 111/191 (59%), Gaps = 3/191 (1%)
Query 8 QEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVE 67
+ E +A TR+ L++ AR L+ RGYA+VG EI AGVT+GA+YH F KA LFR V+
Sbjct 9 KAEAAAQTRDRLVSRARSLFARRGYADVGLTEIVAHAGVTKGALYHHFDSKADLFRAVIA 68
Query 68 VVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFR 127
V +V R+A AA + P + + DA+L S DP ++++L+D P VLGW ++
Sbjct 69 QVHDEVGERVA--AAAEASEDPWEQLLHGCDAFLRASVDPVTQRILLIDGPAVLGWREWK 126
Query 128 DVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRET 187
+ S ++I E I L QPV+PL +L GA++EAA+++A A P T
Sbjct 127 ALDASASERHLTEMIEELIEEEVLPTQPVKPLVHLLSGAMNEAALWLAHASGPDDI-AAT 185
Query 188 RQVLRRLIDGM 198
+ L ++DG+
Sbjct 186 MRALTAMLDGL 196
>gi|326444725|ref|ZP_08219459.1| putative TetR family transcriptional regulator [Streptomyces
clavuligerus ATCC 27064]
Length=196
Score = 116 bits (290), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 72/197 (37%), Positives = 113/197 (58%), Gaps = 6/197 (3%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
R Q ER TR L+ +R+L+ RGY VG EI T A VT+GA+YH FA KA LFR
Sbjct 6 RELQRER---TRHTLLRVSRELFAARGYGAVGLAEIVTAAEVTKGALYHHFAGKAELFRA 62
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
V+ V+++V ++A AA P + + A +L + DP ++++L+D P VLGW
Sbjct 63 VLREVQEEVGHQVAD--AADAREDPWEQLTAGCQEFLTAATDPARQRIMLVDGPAVLGWN 120
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R + + S + + + + G + RQPV PLA +L GA++EAA+++A + P
Sbjct 121 EWRALDEESSARHLAEALADLMERGIVPRQPVAPLAHLLSGAMNEAALWLAASGGPGEL- 179
Query 185 RETRQVLRRLIDGMLNG 201
+TR L R+++ + G
Sbjct 180 ADTRAALSRMLESLRAG 196
>gi|294816397|ref|ZP_06775040.1| TetR family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
gi|294328996|gb|EFG10639.1| TetR family transcriptional regulator [Streptomyces clavuligerus
ATCC 27064]
Length=229
Score = 115 bits (289), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 72/197 (37%), Positives = 113/197 (58%), Gaps = 6/197 (3%)
Query 5 RRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRD 64
R Q ER TR L+ +R+L+ RGY VG EI T A VT+GA+YH FA KA LFR
Sbjct 39 RELQRER---TRHTLLRVSRELFAARGYGAVGLAEIVTAAEVTKGALYHHFAGKAELFRA 95
Query 65 VVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
V+ V+++V ++A AA P + + A +L + DP ++++L+D P VLGW
Sbjct 96 VLREVQEEVGHQVAD--AADAREDPWEQLTAGCQEFLTAATDPARQRIMLVDGPAVLGWN 153
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R + + S + + + + G + RQPV PLA +L GA++EAA+++A + P
Sbjct 154 EWRALDEESSARHLAEALADLMERGIVPRQPVAPLAHLLSGAMNEAALWLAASGGPGEL- 212
Query 185 RETRQVLRRLIDGMLNG 201
+TR L R+++ + G
Sbjct 213 ADTRAALSRMLESLRAG 229
>gi|324999589|ref|ZP_08120701.1| putative TetR family transcriptional regulator [Pseudonocardia
sp. P1]
Length=196
Score = 115 bits (288), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 73/189 (39%), Positives = 107/189 (57%), Gaps = 2/189 (1%)
Query 10 ERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVV 69
E+ A TR+AL+ A +L+ GY VG P + AGVT+GA+YHQF KAALF V+E V
Sbjct 6 EQRARTRDALLDEAERLFAREGYGAVGLPAVVAGAGVTKGALYHQFDGKAALFGAVLERV 65
Query 70 EQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDV 129
+ V R+ AA P D + A A+L+ S P +++L+D P VLGW +R++
Sbjct 66 QARVAERVVE--AARAEQDPWDRLVAGCRAFLDASTAPGTARVMLVDGPAVLGWPAWREI 123
Query 130 AQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQ 189
+R S + + + G+L QPV PLA++L GA++E AM++A R R
Sbjct 124 DERTSGRHLAEALAGLVGLGELEPQPVEPLARLLSGAMNELAMWLAGPGTSAADRAAARA 183
Query 190 VLRRLIDGM 198
L R +DG+
Sbjct 184 ALERTLDGL 192
>gi|312199706|ref|YP_004019767.1| TetR family transcriptional regulator [Frankia sp. EuI1c]
gi|311231042|gb|ADP83897.1| regulatory protein TetR [Frankia sp. EuI1c]
Length=256
Score = 115 bits (288), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 69/199 (35%), Positives = 115/199 (58%), Gaps = 3/199 (1%)
Query 6 RTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDV 65
RT + RS TR AL+ AR+ + +GY GT EI +A VTRGA+YH F DKA LFR+V
Sbjct 50 RTPDNRSLETRTALVAAARRRFAEQGYVATGTEEIVADARVTRGALYHHFRDKADLFREV 109
Query 66 VEVVEQDV-MARMATLVAASGAATPADAIRAAVDAWLEVS--GDPEVRQLILLDAPVVLG 122
++ V +V A + + + A+ +R + L+ S D + ++++L+D P VLG
Sbjct 110 MKEVASEVATALVKSELEATIGGDAWTQLRRGFQSLLDFSTRTDTDFQRIVLVDGPAVLG 169
Query 123 WAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKR 182
+ + +++ G+ + + AI + PV PL +++ L EA++++A + DP +
Sbjct 170 NDAWNTLVEKHGYGLLSEWLERAIAEEVIDPIPVAPLTRLVTALLAEASLYVARSADPSQ 229
Query 183 ARRETRQVLRRLIDGMLNG 201
ARRET VL RL+ G+++
Sbjct 230 ARRETGVVLDRLLSGLVHN 248
>gi|197106377|ref|YP_002131754.1| transcriptional regulator, TetR family [Phenylobacterium zucineum
HLK1]
gi|196479797|gb|ACG79325.1| transcriptional regulator, TetR family [Phenylobacterium zucineum
HLK1]
Length=205
Score = 115 bits (288), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 73/193 (38%), Positives = 104/193 (54%), Gaps = 3/193 (1%)
Query 8 QEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVE 67
+ +R ATR LI AR L+ +GYA V T EI AGVTRGA+YH F DK ALF V+E
Sbjct 12 RHDRGNATRARLIAEARALFASKGYAAVSTQEILEAAGVTRGALYHHFTDKQALFDAVLE 71
Query 68 VVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFR 127
V +V R+ + GA + D + +A L V DPE+ Q+ L+DA V+GW +
Sbjct 72 TVCAEVSGRL--MAETVGATSYLDGLIKGCEAQLRVCADPEILQIYLIDAAAVVGWRRWW 129
Query 128 DVAQRYSLGMTEQLITEAI-RAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRE 186
++ RY++G I A G R + +L GAL++AA+ IA + DP
Sbjct 130 EIDMRYAMGDLRVGIEAACDERGVTDRNQRDAMLTLLSGALNQAALTIADSTDPAGCAEA 189
Query 187 TRQVLRRLIDGML 199
+RR+I+G+
Sbjct 190 LIPTVRRMIEGLF 202
>gi|27377507|ref|NP_769036.1| transcriptional regulator [Bradyrhizobium japonicum USDA 110]
gi|27350651|dbj|BAC47661.1| transcriptional regulatory protein [Bradyrhizobium japonicum
USDA 110]
Length=223
Score = 114 bits (284), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 72/194 (38%), Positives = 109/194 (57%), Gaps = 8/194 (4%)
Query 8 QEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVE 67
Q ER AAT EA++T AR+L+G +G+A EIA A V +GA+YH F K A+F V +
Sbjct 31 QAERRAATSEAILTAARRLFGTQGFAATTMDEIAEGASVAKGAVYHHFRTKEAVFEAVFD 90
Query 68 VVEQDVMARMATLVAASGAATPAD---AIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWA 124
+V +D++A + S A D A+ A + + Q+IL D P VLGW
Sbjct 91 LVSRDLVAEID-----STARVEKDVLAAMVAGTQHYFAATAKGPTGQIILRDGPAVLGWE 145
Query 125 GFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRAR 184
+R++ ++ G + I A+ AG +ARQPV PLA++L+GA+ EAA+ A D RA
Sbjct 146 RWREIDAKHFGGKLPRAIAAAMEAGLIARQPVEPLARLLLGAVTEAAVACAGRADIARAG 205
Query 185 RETRQVLRRLIDGM 198
E + + L++ +
Sbjct 206 AEYARAFKSLVEAL 219
>gi|158317458|ref|YP_001509966.1| TetR family transcriptional regulator [Frankia sp. EAN1pec]
gi|158112863|gb|ABW15060.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec]
Length=222
Score = 114 bits (284), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 67/188 (36%), Positives = 111/188 (60%), Gaps = 4/188 (2%)
Query 3 IKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALF 62
+ R + E++A TR+AL+ AR+ + +GYA GT EI +A VTRGA+YH F DKA LF
Sbjct 1 MTRSRRPEQTADTRQALLAAARRRFAEQGYAATGTEEIVADARVTRGALYHHFRDKADLF 60
Query 63 RDVVEVVEQDVMARMATLVAASGAATPADA---IRAAVDAWLEVS-GDPEVRQLILLDAP 118
R V+E V +V ++ A GA P+DA +R + L++S D + ++++L+D P
Sbjct 61 RTVMEQVAMEVAEQLVAGELARGAELPSDAWTQLRTGFQSLLDISTTDSDFQRIVLIDGP 120
Query 119 VVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD 178
VLG + + +++ + + + A+ G++ PV PL +++ L EA+++ A A
Sbjct 121 AVLGNDAWDQLVEQHGYRLLSEWLERAVAEGRIDPLPVAPLTRLVAALLSEASLYTARAA 180
Query 179 DPKRARRE 186
DP RAR +
Sbjct 181 DPDRARTD 188
>gi|300784077|ref|YP_003764368.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|299793591|gb|ADJ43966.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|340525488|gb|AEK40693.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
S699]
Length=203
Score = 114 bits (284), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 66/184 (36%), Positives = 104/184 (57%), Gaps = 2/184 (1%)
Query 12 SAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQ 71
S +TR AL+ A +L+ RGYA EIA A VT+GA+YH F+ K ALF + VE
Sbjct 9 SESTRSALVDSAVELFTKRGYAGTSLDEIAKRARVTKGALYHHFSGKQALFEAAFDQVES 68
Query 72 DVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQ 131
V R+ ++ +G TP + ++A++ DP +++ + +APVV+GW +R+ +
Sbjct 69 LVYDRLDKIM--TGEGTPWERALGGLNAFIRACLDPAYQRIAIHEAPVVMGWERWREAEE 126
Query 132 RYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVL 191
R S G+ + I AG++ PV A++L GAL AA IA++ DPK+ E V+
Sbjct 127 RCSFGLVRSGLQSLIDAGEVEPVPVEVTARLLFGALSSAATEIASSPDPKKVGAEIEDVI 186
Query 192 RRLI 195
R++
Sbjct 187 VRML 190
>gi|134098215|ref|YP_001103876.1| putative TetR-type transcriptional regulator [Saccharopolyspora
erythraea NRRL 2338]
gi|133910838|emb|CAM00951.1| putative TetR-type transcriptional regulator [Saccharopolyspora
erythraea NRRL 2338]
Length=205
Score = 113 bits (282), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 64/198 (33%), Positives = 109/198 (56%), Gaps = 2/198 (1%)
Query 1 MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAA 60
M+ R + E S TR AL+ A +L+ RGYA EIA A VT+GA+YH F K A
Sbjct 1 MDTARSRRVEYSETTRRALVDSAVELFTERGYAGTSLDEIARAARVTKGALYHHFGGKQA 60
Query 61 LFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVV 120
LF E VE+ V R+++++A +G P + A + +LEV +P +++++ P V
Sbjct 61 LFEAAFEEVERRVTERISSMIADAG--DPWTRMLAGLSGFLEVCLEPSYQRIVVQQGPAV 118
Query 121 LGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDP 180
+GW +R+ +R + GM ++ + I G++ P+ L +V+ GA+ A IA + +P
Sbjct 119 MGWECWREAEERSTYGMVRLVVGQLIEQGEIEPLPLEALTRVVYGAMSAGATTIAGSPEP 178
Query 181 KRARRETRQVLRRLIDGM 198
+ E + + R++ G+
Sbjct 179 RTTSEEVGRCMERVMAGL 196
>gi|118588644|ref|ZP_01546052.1| possible transcriptional regulator, TetR family protein [Stappia
aggregata IAM 12614]
gi|118438630|gb|EAV45263.1| possible transcriptional regulator, TetR family protein [Stappia
aggregata IAM 12614]
Length=202
Score = 112 bits (281), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 74/192 (39%), Positives = 100/192 (53%), Gaps = 10/192 (5%)
Query 4 KRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFR 63
+RRTQ ER A TR+AL+ AR L +GYAE GTPEI A VTRGA+YH FADKA L R
Sbjct 11 ERRTQAERRAETRKALLDAARALIVEKGYAETGTPEIVKAADVTRGALYHHFADKADLMR 70
Query 64 DVV----EVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPV 119
+V E + ++ +R T A TP DA + A+ +++LL+ P
Sbjct 71 ALVHQESEAIAAEINSRTNT------AQTPLDAFMSGASAYFSAMSVAGRARIMLLEGPT 124
Query 120 VLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADD 179
VLG A ++ ++ + A G L P+ PLA +L A D AA+ IA D
Sbjct 125 VLGLAEMAEIDRQTGGATLLDGLRHAAHHGALKNVPLEPLADLLSSAFDRAALAIANGGD 184
Query 180 PKRARRETRQVL 191
K TR++L
Sbjct 185 RKAYETATRKLL 196
>gi|291004364|ref|ZP_06562337.1| putative TetR-type transcriptional regulator [Saccharopolyspora
erythraea NRRL 2338]
Length=197
Score = 111 bits (278), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 62/189 (33%), Positives = 105/189 (56%), Gaps = 2/189 (1%)
Query 10 ERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVV 69
E S TR AL+ A +L+ RGYA EIA A VT+GA+YH F K ALF E V
Sbjct 2 EYSETTRRALVDSAVELFTERGYAGTSLDEIARAARVTKGALYHHFGGKQALFEAAFEEV 61
Query 70 EQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDV 129
E+ V R+++++A +G P + A + +LEV +P +++++ P V+GW +R+
Sbjct 62 ERRVTERISSMIADAG--DPWTRMLAGLSGFLEVCLEPSYQRIVVQQGPAVMGWECWREA 119
Query 130 AQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQ 189
+R + GM ++ + I G++ P+ L +V+ GA+ A IA + +P+ E +
Sbjct 120 EERSTYGMVRLVVGQLIEQGEIEPLPLEALTRVVYGAMSAGATTIAGSPEPRTTSEEVGR 179
Query 190 VLRRLIDGM 198
+ R++ G+
Sbjct 180 CMERVMAGL 188
>gi|288920424|ref|ZP_06414733.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288348153|gb|EFC82421.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=233
Score = 111 bits (277), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 66/188 (36%), Positives = 108/188 (58%), Gaps = 4/188 (2%)
Query 3 IKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALF 62
+ R + E++ TR+ L+ AR+ + +GYA GT EI +A VTRGA+YH F DKA LF
Sbjct 12 VTRSRRPEQTGDTRQVLLAAARRRFAEQGYAATGTEEIVADARVTRGALYHHFRDKADLF 71
Query 63 RDVVEVVEQDVMARMATLVAASGAATPADA---IRAAVDAWLEVS-GDPEVRQLILLDAP 118
R V+E V +V ++ A GA P+DA +R + L++S D + ++++L+D P
Sbjct 72 RTVMEQVAMEVAEQLVAGELARGAELPSDAWTQLRTGFQSLLDISTTDSDFQRIVLIDGP 131
Query 119 VVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD 178
VLG + + +++ + + + A G++ PV PL +++ L EA+++ A A
Sbjct 132 AVLGNDAWDQLVEQHGYRLLSEWLERAAAEGRIDPLPVAPLTRLVAALLSEASLYTARAA 191
Query 179 DPKRARRE 186
DP RAR E
Sbjct 192 DPDRARTE 199
>gi|257055095|ref|YP_003132927.1| transcriptional regulator [Saccharomonospora viridis DSM 43017]
gi|256584967|gb|ACU96100.1| transcriptional regulator [Saccharomonospora viridis DSM 43017]
Length=211
Score = 110 bits (276), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 67/193 (35%), Positives = 108/193 (56%), Gaps = 2/193 (1%)
Query 3 IKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALF 62
+ R +++ + +TR+ALI A L+ RGYA EIA A VT+GA+YH F+ K A+F
Sbjct 5 VTRSRRDDYTESTRDALIGSAVALFTERGYAGTSLDEIARRARVTKGALYHHFSGKQAVF 64
Query 63 RDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLG 122
+ VE +V R+ ++ G TP + A + ++ DP +++ L +APVV+G
Sbjct 65 EAAFDAVETEVKGRLEKILRGDG--TPWERAVAGLREFISSCLDPAYQRIALHEAPVVMG 122
Query 123 WAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKR 182
W +R +RYS G+ + + + I AG + PV +++L GAL AA IA + +P+R
Sbjct 123 WQRWRAAEERYSFGLIKAALQDLIDAGDMISVPVDVASRLLFGALSSAATEIAGSAEPER 182
Query 183 ARRETRQVLRRLI 195
E QV+ L+
Sbjct 183 VGAEIEQVVIALL 195
Lambda K H
0.321 0.133 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 217214446392
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40