BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0084

Length=316
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|254233482|ref|ZP_04926808.1|  formate hydrogenlyase hycD [Myco...   596    2e-168
gi|15607226|ref|NP_214598.1|  formate hydrogenlyase HYCD [Mycobac...   595    3e-168
gi|340625119|ref|YP_004743571.1|  putative formate hydrogenlyase ...   589    2e-166
gi|298527476|ref|ZP_07014885.1|  conserved hypothetical protein [...   496    2e-138
gi|342862431|ref|ZP_08719071.1|  putative formate hydrogenlyase H...   487    1e-135
gi|118465610|ref|YP_884230.1|  hydrogenase-4, C subunit, putative...   474    7e-132
gi|183981670|ref|YP_001849961.1|  formate hydrogenlyase HycD [Myc...   470    1e-130
gi|118617493|ref|YP_905825.1|  formate hydrogenlyase HycD [Mycoba...   467    1e-129
gi|296166649|ref|ZP_06849075.1|  formate hydrogenlyase [Mycobacte...   446    3e-123
gi|240169556|ref|ZP_04748215.1|  formate hydrogenlyase HycD [Myco...   409    2e-112
gi|333991244|ref|YP_004523858.1|  formate hydrogenlyase HycD [Myc...   407    9e-112
gi|258653156|ref|YP_003202312.1|  respiratory-chain NADH dehydrog...   338    9e-91 
gi|269128893|ref|YP_003302263.1|  respiratory-chain NADH dehydrog...   325    4e-87 
gi|336178233|ref|YP_004583608.1|  respiratory-chain NADH dehydrog...   318    8e-85 
gi|331694630|ref|YP_004330869.1|  respiratory-chain NADH dehydrog...   301    8e-80 
gi|317126124|ref|YP_004100236.1|  respiratory-chain NADH dehydrog...   295    1e-77 
gi|289764200|ref|ZP_06523578.1|  formate hydrogenlyase [Mycobacte...   291    7e-77 
gi|258593561|emb|CBE69902.1|  Similar to membrane-bound [NiFe]-hy...   272    7e-71 
gi|302039530|ref|YP_003799852.1|  putative formate hydrogenlyase,...   262    6e-68 
gi|119718687|ref|YP_925652.1|  putative formate hydrogenlyase Hyc...   258    8e-67 
gi|333983294|ref|YP_004512504.1|  hydrogenase subunit [Methylomon...   239    3e-61 
gi|144898670|emb|CAM75534.1|  NADH dehydrogenase [Magnetospirillu...   235    8e-60 
gi|91202881|emb|CAJ72520.1|  similar to membrane-bound [NiFe]-hyd...   234    2e-59 
gi|147919457|ref|YP_686803.1|  hydrogenase, membrane subunit 3-li...   233    4e-59 
gi|344943802|ref|ZP_08783088.1|  hydrogenase subunit [Methylobact...   230    2e-58 
gi|344341649|ref|ZP_08772566.1|  hydrogenase subunit [Thiocapsa m...   227    2e-57 
gi|337266649|ref|YP_004610704.1|  putative hydrogenase protein [M...   227    2e-57 
gi|182414277|ref|YP_001819343.1|  hydrogenase, membrane subunit 3...   226    3e-57 
gi|296446949|ref|ZP_06888884.1|  NADH dehydrogenase [Methylosinus...   225    6e-57 
gi|182679426|ref|YP_001833572.1|  NADH dehydrogenase [Beijerincki...   225    7e-57 
gi|260575427|ref|ZP_05843426.1|  NADH dehydrogenase [Rhodobacter ...   223    3e-56 
gi|114775568|ref|ZP_01451136.1|  hydrogenase subunit [Mariprofund...   222    5e-56 
gi|83309309|ref|YP_419573.1|  formate hydrogenlyase subunit 4 [Ma...   222    7e-56 
gi|115522978|ref|YP_779889.1|  respiratory-chain NADH dehydrogena...   220    2e-55 
gi|344345383|ref|ZP_08776235.1|  hydrogenase subunit [Marichromat...   220    2e-55 
gi|91978317|ref|YP_570976.1|  respiratory-chain NADH dehydrogenas...   219    5e-55 
gi|312113078|ref|YP_004010674.1|  NADH dehydrogenase [Rhodomicrob...   219    6e-55 
gi|56477809|ref|YP_159398.1|  formate hydrogenlyase membrane subu...   218    1e-54 
gi|198283915|ref|YP_002220236.1|  formate hydrogenlyase membrane ...   216    4e-54 
gi|90422449|ref|YP_530819.1|  respiratory-chain NADH dehydrogenas...   216    5e-54 
gi|325288315|ref|YP_004264496.1|  respiratory-chain NADH dehydrog...   215    1e-53 
gi|89902060|ref|YP_524531.1|  respiratory-chain NADH dehydrogenas...   214    1e-53 
gi|27381451|ref|NP_772980.1|  hydrogenlyase component [Bradyrhizo...   213    3e-53 
gi|86748386|ref|YP_484882.1|  respiratory-chain NADH dehydrogenas...   212    5e-53 
gi|343917163|gb|EGV27972.1|  hydrogenase subunit [Thiorhodococcus...   212    6e-53 
gi|91786819|ref|YP_547771.1|  respiratory-chain NADH dehydrogenas...   212    7e-53 
gi|148260399|ref|YP_001234526.1|  formate hydrogenlyase subunit 4...   212    8e-53 
gi|299132785|ref|ZP_07025980.1|  respiratory-chain NADH dehydroge...   210    3e-52 
gi|339834212|gb|EGQ61992.1|  hydrogenase-4, C subunit [Acidithiob...   209    7e-52 
gi|338980410|ref|ZP_08631686.1|  Formate hydrogenlyase subunit 4-...   208    1e-51 


>gi|254233482|ref|ZP_04926808.1| formate hydrogenlyase hycD [Mycobacterium tuberculosis C]
 gi|308394377|ref|ZP_07491664.2| hypothetical protein TMLG_00822 [Mycobacterium tuberculosis SUMu012]
 gi|124603275|gb|EAY61550.1| formate hydrogenlyase hycD [Mycobacterium tuberculosis C]
 gi|308367706|gb|EFP56557.1| hypothetical protein TMLG_00822 [Mycobacterium tuberculosis SUMu012]
 gi|339293153|gb|AEJ45264.1| formate hydrogenlyase hycD [Mycobacterium tuberculosis CCDC5079]
 gi|339296802|gb|AEJ48912.1| formate hydrogenlyase hycD [Mycobacterium tuberculosis CCDC5180]
Length=319

 Score =  596 bits (1536),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 316/316 (100%), Positives = 316/316 (100%), Gaps = 0/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT
Sbjct  4    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  63

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT
Sbjct  64   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  123

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF
Sbjct  124  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  183

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA
Sbjct  184  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  243

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL
Sbjct  244  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  303

Query  301  LALLAVTAANFFTVGA  316
            LALLAVTAANFFTVGA
Sbjct  304  LALLAVTAANFFTVGA  319


>gi|15607226|ref|NP_214598.1| formate hydrogenlyase HYCD [Mycobacterium tuberculosis H37Rv]
 gi|15839465|ref|NP_334502.1| formate hydrogenlyase, subunit 4 [Mycobacterium tuberculosis 
CDC1551]
 gi|31791262|ref|NP_853755.1| formate hydrogenlyase HYCD [Mycobacterium bovis AF2122/97]
 68 more sequence titles
 Length=316

 Score =  595 bits (1534),  Expect = 3e-168, Method: Compositional matrix adjust.
 Identities = 316/316 (100%), Positives = 316/316 (100%), Gaps = 0/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT
Sbjct  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT
Sbjct  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF
Sbjct  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA
Sbjct  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL
Sbjct  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300

Query  301  LALLAVTAANFFTVGA  316
            LALLAVTAANFFTVGA
Sbjct  301  LALLAVTAANFFTVGA  316


>gi|340625119|ref|YP_004743571.1| putative formate hydrogenlyase HYCD [Mycobacterium canettii CIPT 
140010059]
 gi|340003309|emb|CCC42426.1| putative formate hydrogenlyase HYCD (FHL) [Mycobacterium canettii 
CIPT 140010059]
Length=316

 Score =  589 bits (1518),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 313/316 (99%), Positives = 313/316 (99%), Gaps = 0/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MSYLAGAAQIGGVMVGAPLVIGMTRQVR RWEGRAGAGLLQPWRDLLKQLGKQQITPAGT
Sbjct  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRGRWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT
Sbjct  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF
Sbjct  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA
Sbjct  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLFLPWGIAGAAPTALDVL GVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL
Sbjct  241  NLFLPWGIAGAAPTALDVLIGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300

Query  301  LALLAVTAANFFTVGA  316
            LALLAVTAANFFTV A
Sbjct  301  LALLAVTAANFFTVQA  316


>gi|298527476|ref|ZP_07014885.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298497270|gb|EFI32564.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
Length=316

 Score =  496 bits (1277),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 306/316 (97%), Positives = 307/316 (98%), Gaps = 1/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT
Sbjct  2    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  61

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT
Sbjct  62   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  121

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF
Sbjct  122  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  181

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVA T R       +HLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA
Sbjct  182  VALVIVIVAWTTR-SGSVRWSHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL
Sbjct  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300

Query  301  LALLAVTAANFFTVGA  316
            LALLAVTAANFFTVGA
Sbjct  301  LALLAVTAANFFTVGA  316


>gi|342862431|ref|ZP_08719071.1| putative formate hydrogenlyase HycD [Mycobacterium colombiense 
CECT 3035]
 gi|342130102|gb|EGT83436.1| putative formate hydrogenlyase HycD [Mycobacterium colombiense 
CECT 3035]
Length=319

 Score =  487 bits (1253),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 268/316 (85%), Positives = 290/316 (92%), Gaps = 0/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            +SY AGA Q+G V+ G+PLV+G+TRQVRARWEGR GAG+LQPW D++KQLGKQQI P GT
Sbjct  4    LSYAAGATQLGAVVAGSPLVVGLTRQVRARWEGRVGAGVLQPWYDIVKQLGKQQIKPLGT  63

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T+VFAAAPVIVA +TLLIAAIAPLVATGSPLD SADLFAVVGLLF+GTVALTLAGIDTGT
Sbjct  64   TVVFAAAPVIVAASTLLIAAIAPLVATGSPLDASADLFAVVGLLFVGTVALTLAGIDTGT  123

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALS+PAGSANLGALVA TI HPG VVSLA VLAF
Sbjct  124  SFGGMGASREITIAALVEPTILLAVFALSMPAGSANLGALVAHTIAHPGGVVSLAAVLAF  183

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA
Sbjct  184  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  243

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLF+PWGIA   P A+ ++ G+VAV AKVA+LA +LAT EVF+AKLRLFRVPELLAGSF+
Sbjct  244  NLFVPWGIADGGPGAIGIVIGLVAVVAKVAVLAAVLATVEVFMAKLRLFRVPELLAGSFV  303

Query  301  LALLAVTAANFFTVGA  316
            LALLAV AANFF V A
Sbjct  304  LALLAVIAANFFGVPA  319


>gi|118465610|ref|YP_884230.1| hydrogenase-4, C subunit, putative [Mycobacterium avium 104]
 gi|118166897|gb|ABK67794.1| hydrogenase-4, C subunit, putative [Mycobacterium avium 104]
Length=319

 Score =  474 bits (1220),  Expect = 7e-132, Method: Compositional matrix adjust.
 Identities = 272/313 (87%), Positives = 287/313 (92%), Gaps = 0/313 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MSY+AGAAQI  VM GAPLVIG  RQVRAR EGR G G+LQPWRDL KQLGKQQI+P GT
Sbjct  4    MSYVAGAAQILAVMAGAPLVIGAMRQVRARLEGRGGGGVLQPWRDLRKQLGKQQISPQGT  63

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T+VFAAAP IVAGTTLLI AIAP+VATGSPLD +ADLFAVVGLLFLGTVALTLAGIDTGT
Sbjct  64   TVVFAAAPAIVAGTTLLIVAIAPIVATGSPLDAAADLFAVVGLLFLGTVALTLAGIDTGT  123

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALV +TIDHPG VVSL G+LAF
Sbjct  124  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVTNTIDHPGQVVSLTGLLAF  183

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWA+GMRLTVLLALLA
Sbjct  184  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWASGMRLTVLLALLA  243

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLFLPWGIAG  P+A+DV  G+ A+ AKV +LAV LA  EVF+AKLRLFRVPELLAGSFL
Sbjct  244  NLFLPWGIAGGHPSAVDVAIGLAAITAKVTVLAVALAGAEVFIAKLRLFRVPELLAGSFL  303

Query  301  LALLAVTAANFFT  313
            LALLAVTAANFFT
Sbjct  304  LALLAVTAANFFT  316


>gi|183981670|ref|YP_001849961.1| formate hydrogenlyase HycD [Mycobacterium marinum M]
 gi|183174996|gb|ACC40106.1| formate hydrogenlyase HycD [Mycobacterium marinum M]
Length=319

 Score =  470 bits (1210),  Expect = 1e-130, Method: Compositional matrix adjust.
 Identities = 254/313 (82%), Positives = 283/313 (91%), Gaps = 0/313 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MS +AGAAQIG V++GAPLVIG+ RQ+RAR EGR GAG+LQPWRDL KQL KQQ+TP GT
Sbjct  4    MSAMAGAAQIGAVILGAPLVIGLMRQIRARSEGRCGAGILQPWRDLRKQLRKQQVTPEGT  63

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T VFA AP +VA TTLLIAAIAPLVATGSPLDP  DLF VVGLLFLGTVALTLAGIDTGT
Sbjct  64   TAVFAVAPAVVAATTLLIAAIAPLVATGSPLDPVGDLFVVVGLLFLGTVALTLAGIDTGT  123

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPA SANLGA+VA ++++P  VVSLAG+LAF
Sbjct  124  SFGGMGASREITIAALVEPTILLAVFALSIPAKSANLGAIVAFSLENPAEVVSLAGILAF  183

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIV++AETGRLPVDNPATHLELTMVHEAMVLEYAGPRL ++EWA+GMRLTVLLALLA
Sbjct  184  VALVIVVIAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLGVIEWASGMRLTVLLALLA  243

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLF+PWGIAGA P+ + +  G+ A++ KVAI A +LAT EVF+AKLRLFRVPELLAGSFL
Sbjct  244  NLFVPWGIAGADPSLIGIAVGIAAISIKVAIAAGVLATVEVFIAKLRLFRVPELLAGSFL  303

Query  301  LALLAVTAANFFT  313
            LALLAVT+ANFFT
Sbjct  304  LALLAVTSANFFT  316


>gi|118617493|ref|YP_905825.1| formate hydrogenlyase HycD [Mycobacterium ulcerans Agy99]
 gi|118569603|gb|ABL04354.1| formate hydrogenlyase HycD [Mycobacterium ulcerans Agy99]
Length=316

 Score =  467 bits (1201),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 253/313 (81%), Positives = 282/313 (91%), Gaps = 0/313 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            MS +AGAAQIG V++GAPLVIG+ RQ+RAR EGR GAG+LQPWRDL KQL KQQ+TP GT
Sbjct  1    MSAMAGAAQIGAVILGAPLVIGLMRQIRARSEGRCGAGILQPWRDLHKQLRKQQVTPEGT  60

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T VFA AP +VA TTLLIAAIAPLVATGSPLDP  DLF VVGLLFLGTVALTLAGIDTGT
Sbjct  61   TAVFAVAPAVVAATTLLIAAIAPLVATGSPLDPVGDLFVVVGLLFLGTVALTLAGIDTGT  120

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPA SANLGA+VA ++++P  VVSLAG+LAF
Sbjct  121  SFGGMGASREITIAALVEPTILLAVFALSIPAKSANLGAIVAFSLENPAEVVSLAGILAF  180

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIV++AETGRL VDNPATHLELTMVHEAMVLEYAGPRL ++EWA+GMRLTVLLALLA
Sbjct  181  VALVIVVIAETGRLSVDNPATHLELTMVHEAMVLEYAGPRLGVIEWASGMRLTVLLALLA  240

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLF+PWGIAGA P+ + +  G+ A++ KVAI A +LAT EVF+AKLRLFRVPELLAGSFL
Sbjct  241  NLFVPWGIAGADPSLIGIAVGIAAISIKVAIAAGVLATVEVFIAKLRLFRVPELLAGSFL  300

Query  301  LALLAVTAANFFT  313
            LALLAVT+ANFFT
Sbjct  301  LALLAVTSANFFT  313


>gi|296166649|ref|ZP_06849075.1| formate hydrogenlyase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897984|gb|EFG77564.1| formate hydrogenlyase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=319

 Score =  446 bits (1146),  Expect = 3e-123, Method: Compositional matrix adjust.
 Identities = 276/316 (88%), Positives = 291/316 (93%), Gaps = 0/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            +S +AGAAQI  VM GAPLV+G+TRQVRARWEGRAGAG+LQPWRD++KQLGKQQITP GT
Sbjct  4    VSCVAGAAQIFAVMAGAPLVVGLTRQVRARWEGRAGAGVLQPWRDIVKQLGKQQITPNGT  63

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T+VFAAAP IVAGTTLLIAAIAPLVATGSPLD SADLFAVVGLLF+GTVALTLAGIDTGT
Sbjct  64   TVVFAAAPAIVAGTTLLIAAIAPLVATGSPLDGSADLFAVVGLLFVGTVALTLAGIDTGT  123

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALS+PAGSANLGALV+ TI HPG VVSLA VLAF
Sbjct  124  SFGGMGASREITIAALVEPTILLAVFALSMPAGSANLGALVSHTITHPGQVVSLAAVLAF  183

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
             ALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA
Sbjct  184  AALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  243

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLF PWGIAG  P A+ VL G+ AVAAKVA+LA  LAT EVF+AKLRLFRVPELLAGSFL
Sbjct  244  NLFAPWGIAGDKPGAVAVLVGLAAVAAKVAVLAASLATMEVFVAKLRLFRVPELLAGSFL  303

Query  301  LALLAVTAANFFTVGA  316
            LALLAV AANFF V A
Sbjct  304  LALLAVVAANFFAVPA  319


>gi|240169556|ref|ZP_04748215.1| formate hydrogenlyase HycD [Mycobacterium kansasii ATCC 12478]
Length=319

 Score =  409 bits (1052),  Expect = 2e-112, Method: Compositional matrix adjust.
 Identities = 260/316 (83%), Positives = 285/316 (91%), Gaps = 0/316 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            +S +AGAAQIG VM GAPLV+G+ RQVRAR EGR GAG+LQPWRDL KQL KQQ+TP GT
Sbjct  4    LSAVAGAAQIGAVMTGAPLVVGLMRQVRARSEGRCGAGVLQPWRDLRKQLRKQQVTPDGT  63

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T+VFAAAPV+VA TTLLIAAIAPL ATGSPLD  ADLF VVGLLFLGTVALTLAGIDTGT
Sbjct  64   TLVFAAAPVVVAATTLLIAAIAPLAATGSPLDSVADLFVVVGLLFLGTVALTLAGIDTGT  123

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGA+VA ++++P  +VSLAG+LAF
Sbjct  124  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGAVVAFSLENPAEMVSLAGILAF  183

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIV++AETGRLPVDNPATHLELTMVHEAMVLEYAGP+LALVEWA+GMRLTVLLALLA
Sbjct  184  VALVIVVIAETGRLPVDNPATHLELTMVHEAMVLEYAGPKLALVEWASGMRLTVLLALLA  243

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLF PWGIAG  P+ + V  GV AVA KVA+ AV+LA  EVF+AKLRLFRVPELLAGSFL
Sbjct  244  NLFFPWGIAGDRPSLVGVGIGVAAVAIKVAVAAVVLAGAEVFIAKLRLFRVPELLAGSFL  303

Query  301  LALLAVTAANFFTVGA  316
            LALLAVT+ANFFT  A
Sbjct  304  LALLAVTSANFFTAQA  319


>gi|333991244|ref|YP_004523858.1| formate hydrogenlyase HycD [Mycobacterium sp. JDM601]
 gi|333487212|gb|AEF36604.1| formate hydrogenlyase HycD [Mycobacterium sp. JDM601]
Length=317

 Score =  407 bits (1047),  Expect = 9e-112, Method: Compositional matrix adjust.
 Identities = 251/313 (81%), Positives = 273/313 (88%), Gaps = 0/313 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            M+YLAG  Q+ GV+ GAPLVIG+ RQVRAR EGR GAG+ QPWRD+ K LGKQ + P GT
Sbjct  1    MTYLAGFLQVAGVIAGAPLVIGLMRQVRARAEGRTGAGIRQPWRDMRKLLGKQLLNPRGT  60

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            T  FAAAP  +A TTL+I A APLVATGSPLDP ADL  VVGLLFLGTVAL LAGIDT T
Sbjct  61   TWAFAAAPAALAATTLVIVAAAPLVATGSPLDPVADLITVVGLLFLGTVALALAGIDTAT  120

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            +FGGMGASREITIAALVEPTILLAVFALSIPAGSANL A+V +T+DHPG VVSLA  LAF
Sbjct  121  AFGGMGASREITIAALVEPTILLAVFALSIPAGSANLSAIVGNTVDHPGQVVSLASALAF  180

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGP+LALVEWA+GMRLTVLLALLA
Sbjct  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPKLALVEWASGMRLTVLLALLA  240

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
            NLF PWGIAGA P+ LDV+ GV A+A KVA+LA  LA  EVF+A+LRLFRVPELLAGSFL
Sbjct  241  NLFFPWGIAGAHPSLLDVVVGVGAIAIKVALLATALAAVEVFIARLRLFRVPELLAGSFL  300

Query  301  LALLAVTAANFFT  313
            LALLAVTAANFF+
Sbjct  301  LALLAVTAANFFS  313


>gi|258653156|ref|YP_003202312.1| respiratory-chain NADH dehydrogenase subunit 1 [Nakamurella multipartita 
DSM 44233]
 gi|258556381|gb|ACV79323.1| respiratory-chain NADH dehydrogenase, subunit 1 [Nakamurella 
multipartita DSM 44233]
Length=316

 Score =  338 bits (866),  Expect = 9e-91, Method: Compositional matrix adjust.
 Identities = 204/313 (66%), Positives = 244/313 (78%), Gaps = 3/313 (0%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            M+ L    Q+  V+  +PL+IG+ RQVRAR EGRAGAG+ QPWRDL K + K+ + P GT
Sbjct  5    MAGLGSLLQVLIVLALSPLLIGLMRQVRARLEGRAGAGVGQPWRDLRKLMRKRPVAPQGT  64

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            ++VF  AP+++  T L++A +AP V     L P +DLFAVV LL LGTVAL LAGIDTGT
Sbjct  65   SVVFRTAPLVLVATCLVVAVVAPFVTATPALSPVSDLFAVVALLTLGTVALALAGIDTGT  124

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            +FGG+GASRE TI ALVEPT+L+A+FALS+P GS NLGA+VAST+  P  V+S   +LA 
Sbjct  125  AFGGLGASRESTIIALVEPTLLVAIFALSVPVGSTNLGAIVASTLADPAGVLSPVSLLAA  184

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
             ALV+VI+AETGRLPVDNP+THLELTMVHEAM+LEY+GP LALVE AA MRLTV L LLA
Sbjct  185  AALVVVIIAETGRLPVDNPSTHLELTMVHEAMILEYSGPDLALVELAAAMRLTVFLGLLA  244

Query  241  NLFLPWGIA-GAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSF  299
            NLFLPWGIA G+ P  LD+  GVVA  AKVA+L  LLA  EVFLAKLRLFRVPELLAGSF
Sbjct  245  NLFLPWGIATGSGP--LDLGVGVVAFVAKVAVLGTLLAAGEVFLAKLRLFRVPELLAGSF  302

Query  300  LLALLAVTAANFF  312
            ++ LLAV A+ F 
Sbjct  303  VMGLLAVGASFFL  315


>gi|269128893|ref|YP_003302263.1| respiratory-chain NADH dehydrogenase subunit 1 [Thermomonospora 
curvata DSM 43183]
 gi|268313851|gb|ACZ00226.1| respiratory-chain NADH dehydrogenase, subunit 1 [Thermomonospora 
curvata DSM 43183]
Length=307

 Score =  325 bits (834),  Expect = 4e-87, Method: Compositional matrix adjust.
 Identities = 195/293 (67%), Positives = 225/293 (77%), Gaps = 6/293 (2%)

Query  7    AAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAA  66
            AAQ+  + VG+P ++G+ RQVRAR EGRAGAG+ QP RDL K L K+ I P GT  +F A
Sbjct  5    AAQVVLIGVGSPFLVGLMRQVRARLEGRAGAGIAQPMRDLRKLLRKEPIAPHGTGWLFRA  64

Query  67   APVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMG  126
            AP+++A T L++AA+ P   T SPLDP+ADLFAV  LL LGTVAL L G+DTGT+FGGMG
Sbjct  65   APLVLAATALVVAAVGPFATTDSPLDPAADLFAVTALLALGTVALALGGLDTGTAFGGMG  124

Query  127  ASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIV  186
            ASRE+T+ ALVEPTILLAVFALSI  GS NLG + AS  + P  VVS   +LA VAL+IV
Sbjct  125  ASREMTVMALVEPTILLAVFALSIRVGSTNLGQIAASVAEDPLSVVSPVSLLAAVALIIV  184

Query  187  IVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPW  246
             VAETGR+PVDNPATHLELTM+HEAMVLEYAGP LAL+EWA+ MRLTVLL L A LF PW
Sbjct  185  TVAETGRIPVDNPATHLELTMIHEAMVLEYAGPDLALIEWASAMRLTVLLGLFAGLFTPW  244

Query  247  GIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSF  299
            GI  A P AL V       A KVA+L  LLA  EVF+AKLRLFRVPELLAGSF
Sbjct  245  GITLALPLALAVF------ALKVAVLGALLAAAEVFMAKLRLFRVPELLAGSF  291


>gi|336178233|ref|YP_004583608.1| respiratory-chain NADH dehydrogenase subunit 1 [Frankia symbiont 
of Datisca glomerata]
 gi|334859213|gb|AEH09687.1| respiratory-chain NADH dehydrogenase subunit 1 [Frankia symbiont 
of Datisca glomerata]
Length=317

 Score =  318 bits (814),  Expect = 8e-85, Method: Compositional matrix adjust.
 Identities = 194/307 (64%), Positives = 231/307 (76%), Gaps = 2/307 (0%)

Query  9    QIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAP  68
            Q+  V+ GAPL+ G+ RQVRAR EGRAGAG+ QPWRDL K L KQ ITP GT   F  AP
Sbjct  12   QVTVVVAGAPLLTGLMRQVRARMEGRAGAGVGQPWRDLRKLLRKQPITPVGTGPAFRLAP  71

Query  69   VIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGAS  128
            +++  TTL++AA+ PL +T +P+  SADL  VV LL LGTV L LAG+DTGT+FGGMGAS
Sbjct  72   LLLVATTLVVAALVPLASTATPVRDSADLLVVVTLLALGTVILALAGLDTGTAFGGMGAS  131

Query  129  REITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIV  188
            RE+T+ ALVEPTILL+V ALSIPAGS NL A+VA  +  P  + S A +LA VAL +V +
Sbjct  132  REMTVVALVEPTILLSVVALSIPAGSTNLPAIVAHGVHDPARLASPASLLAGVALAVVTL  191

Query  189  AETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGI  248
            AETGRLPVDNP+THLELTM+HEAM+LEYAGP LAL+E  A MRLTVLL LL +LF+PWGI
Sbjct  192  AETGRLPVDNPSTHLELTMIHEAMILEYAGPDLALIELGAQMRLTVLLGLLTSLFVPWGI  251

Query  249  AGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTA  308
            A     A  +   +   A KVA+L   LA  EVF AK+RLF+VPELLAGSFLLALLAV  
Sbjct  252  ATGT-AAAALPLALALFAGKVALLGAGLAAAEVFWAKMRLFKVPELLAGSFLLALLAV-G  309

Query  309  ANFFTVG  315
            A+FF  G
Sbjct  310  ASFFLPG  316


>gi|331694630|ref|YP_004330869.1| respiratory-chain NADH dehydrogenase subunit 1 [Pseudonocardia 
dioxanivorans CB1190]
 gi|326949319|gb|AEA23016.1| respiratory-chain NADH dehydrogenase subunit 1 [Pseudonocardia 
dioxanivorans CB1190]
Length=315

 Score =  301 bits (771),  Expect = 8e-80, Method: Compositional matrix adjust.
 Identities = 188/294 (64%), Positives = 226/294 (77%), Gaps = 1/294 (0%)

Query  16   GAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTT  75
            GAPL++G+ RQVRAR EGRAG G+ QPWRDL K + KQ I+P GTT VF  APV++   T
Sbjct  19   GAPLLLGLMRQVRARLEGRAGPGVGQPWRDLRKLVRKQSISPRGTTEVFRVAPVLLVAMT  78

Query  76   LLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAA  135
            L++A +APLV T S + P ADLF VV LL   TV + LAG+D+GT+FGGMGASRE+T+ A
Sbjct  79   LVVAVVAPLVTTASAVPPVADLFVVVALLAHATVVIALAGLDSGTAFGGMGASREVTVLA  138

Query  136  LVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLP  195
            LVEPT L+A+FALS+P GS +L  +V + +D P  ++S A +LA VAL  VIVAETGRLP
Sbjct  139  LVEPTALVAIFALSVPTGSTSLPTIVGTALDDPQRLISPASLLAAVALAAVIVAETGRLP  198

Query  196  VDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTA  255
            VDNP+THLELTM+HEAMVLEYAGP LALVE  + MRL+V L L  +LF+PWGIA  A T 
Sbjct  199  VDNPSTHLELTMIHEAMVLEYAGPDLALVELGSAMRLSVYLGLFTSLFVPWGIATTA-TP  257

Query  256  LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAA  309
            L +  GVVA+  KV ++   LA  EVFLAKLRLFRVPELLAGSFLLALLAVT A
Sbjct  258  LALALGVVALVVKVGVVGAGLAALEVFLAKLRLFRVPELLAGSFLLALLAVTTA  311


>gi|317126124|ref|YP_004100236.1| respiratory-chain NADH dehydrogenase, subunit 1 [Intrasporangium 
calvum DSM 43043]
 gi|315590212|gb|ADU49509.1| respiratory-chain NADH dehydrogenase, subunit 1 [Intrasporangium 
calvum DSM 43043]
Length=319

 Score =  295 bits (754),  Expect = 1e-77, Method: Compositional matrix adjust.
 Identities = 171/291 (59%), Positives = 214/291 (74%), Gaps = 3/291 (1%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G+ RQVRAR EGR G G+ QPWRDL K L K+ I+P G+++VF AAP +    +L++ A+
Sbjct  29   GLMRQVRARLEGRVGGGVGQPWRDLRKLLRKEAISPEGSSLVFVAAPAVALSASLVVVAV  88

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
            AP + TGSPLD  ADL+AVV L+ LG+VA  LAG+DTG++FGGMG+SR + +AAL EPT+
Sbjct  89   APFIVTGSPLDAVADLYAVVSLMLLGSVAFALAGLDTGSAFGGMGSSRTMMVAALAEPTL  148

Query  142  LLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPAT  201
            LL  FAL++  GS+NLG LV  +   PG V S A +LA  AL IV+VAE GRLPVDNP T
Sbjct  149  LLTGFALAVRVGSSNLGQLVDRSQQAPGEVFSPAVLLAAAALAIVVVAEAGRLPVDNPTT  208

Query  202  HLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAA-PTALDVLT  260
            HLELTM+HEA +LEYAG  LA+VE A+ +RLT+LL L  NLFLPWGI GAA P AL +  
Sbjct  209  HLELTMIHEATILEYAGRDLAVVELASSIRLTILLGLWVNLFLPWGIPGAATPVALAL--  266

Query  261  GVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANF  311
            G +    KV + A  L+  EVF+AK RLFRVPELLAGSFL  +LAV+ + F
Sbjct  267  GALVFLLKVGLAAAALSAAEVFMAKWRLFRVPELLAGSFLFGVLAVSTSFF  317


>gi|289764200|ref|ZP_06523578.1| formate hydrogenlyase [Mycobacterium tuberculosis GM 1503]
 gi|289711706|gb|EFD75722.1| formate hydrogenlyase [Mycobacterium tuberculosis GM 1503]
Length=156

 Score =  291 bits (746),  Expect = 7e-77, Method: Compositional matrix adjust.
 Identities = 155/156 (99%), Positives = 156/156 (100%), Gaps = 0/156 (0%)

Query  161  VASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPR  220
            +ASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPR
Sbjct  1    MASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPR  60

Query  221  LALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFE  280
            LALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFE
Sbjct  61   LALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFE  120

Query  281  VFLAKLRLFRVPELLAGSFLLALLAVTAANFFTVGA  316
            VFLAKLRLFRVPELLAGSFLLALLAVTAANFFTVGA
Sbjct  121  VFLAKLRLFRVPELLAGSFLLALLAVTAANFFTVGA  156


>gi|258593561|emb|CBE69902.1| Similar to membrane-bound [NiFe]-hydrogenase-3, subunit D [NC10 
bacterium 'Dutch sediment']
Length=314

 Score =  272 bits (695),  Expect = 7e-71, Method: Compositional matrix adjust.
 Identities = 154/298 (52%), Positives = 212/298 (72%), Gaps = 3/298 (1%)

Query  15   VGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGT  74
            +GAPL++G+ R+V+AR +GR GAGLLQP+ DL K L K+ +    T+ +F   P ++A T
Sbjct  17   LGAPLLVGLVRRVKARLQGRRGAGLLQPYADLRKLLAKEAVVSETTSWIFRFTPYLLAAT  76

Query  75   TLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIA  134
             LL A + PL+ T +PL    ++  ++ L  LGT  L LAG+D G++FGGMG+SRE+ +A
Sbjct  77   MLLSALLVPLLTTRTPLGFLGNIIVLMYLFLLGTFFLALAGLDAGSAFGGMGSSREMAVA  136

Query  135  ALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRL  194
            AL EPT+++A+FA+++ AG+  L  ++         +++   +LAF+A  IV +AETGRL
Sbjct  137  ALAEPTVMIAIFAIALRAGNTGLDEIIRRGAADSLLLLTPGHLLAFMAFFIVAIAETGRL  196

Query  195  PVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIA-GAAP  253
            PVDNPATHLELTM+HEAMVLEY+G  L L+EWAAGM+L + LALL+NLF PWG+A    P
Sbjct  197  PVDNPATHLELTMIHEAMVLEYSGRHLMLIEWAAGMKLLIFLALLSNLFFPWGVALTVTP  256

Query  254  TALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANF  311
             AL V    VA+ AKV++LAV +A  E  +AKLRLFR+P LL+GSF LALLAV +  F
Sbjct  257  PALAV--AFVALVAKVSVLAVGIAVLETAVAKLRLFRLPALLSGSFALALLAVISFLF  312


>gi|302039530|ref|YP_003799852.1| putative formate hydrogenlyase, membrane subunit [Candidatus 
Nitrospira defluvii]
 gi|300607594|emb|CBK43927.1| putative Formate hydrogenlyase, membrane subunit [Candidatus 
Nitrospira defluvii]
Length=318

 Score =  262 bits (669),  Expect = 6e-68, Method: Compositional matrix adjust.
 Identities = 142/292 (49%), Positives = 205/292 (71%), Gaps = 4/292 (1%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            +P V+G+ R+V+AR + R GA L QP+ DL K   KQ +  + T+ +F AAP IV  +T+
Sbjct  21   SPFVVGLIRKVKARLQCRRGASLFQPYADLAKLFRKQPVISSTTSWIFTAAPYIVFASTV  80

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
                + P+  + +PL+ + ++ A+V LL LGT  L LAG+D G++FGGMG+SRE  +A L
Sbjct  81   AAGLLMPVFVSHTPLNFAGNIIALVYLLALGTFFLILAGLDAGSAFGGMGSSREAIVATL  140

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVS-LAGVLAFVALVIVIVAETGRLP  195
             EP ++L++ ++++ AGS NL  +V  +    G VV+  A ++A  AL IV +AETGR+P
Sbjct  141  AEPAMMLSILSIALTAGSTNLSTIVHQSALMEGVVVAPPAHLMALAALFIVTLAETGRVP  200

Query  196  VDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGA-APT  254
            VDNPATHLELTM+HEAM+LEY+G  LAL+EWAAG++L V L L+ N+F PWGIA + AP+
Sbjct  201  VDNPATHLELTMIHEAMLLEYSGRYLALMEWAAGIKLLVFLTLIVNVFAPWGIATSLAPS  260

Query  255  ALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAV  306
            A+ V  G++    KVA LA+++   E   AKLRLFRVPE+L  +F+L+LLA+
Sbjct  261  AIAV--GLLVYLGKVAALALVIGVIESMFAKLRLFRVPEMLGAAFILSLLAL  310


>gi|119718687|ref|YP_925652.1| putative formate hydrogenlyase HycD (FHL) [Nocardioides sp. JS614]
 gi|119539348|gb|ABL83965.1| putative formate hydrogenlyase HycD (FHL) [Nocardioides sp. JS614]
Length=316

 Score =  258 bits (659),  Expect = 8e-67, Method: Compositional matrix adjust.
 Identities = 165/293 (57%), Positives = 217/293 (75%), Gaps = 1/293 (0%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            +PL++G+ RQVRAR EGRAGAG+LQPWRDL K LGK+ +T  G + + AA P+++  ++L
Sbjct  20   SPLLVGVMRQVRARLEGRAGAGVLQPWRDLRKLLGKEPLTADGVSWISAAGPLVLVASSL  79

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
            L+ A+ P++ T +      DLF VV  L +G+VAL L G+D GT+FGGMG+SR + IAAL
Sbjct  80   LLCALTPVLGTATLDRVPNDLFVVVAALLIGSVALALVGLDAGTAFGGMGSSRHMMIAAL  139

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPV  196
            VEPT+L++V+ALSIP GS+ L  +V + +DHP  + S   +LA + L I IVAET RLP+
Sbjct  140  VEPTVLVSVYALSIPVGSSVLSHIVEARLDHPATIWSPVSLLALLGLAIAIVAETARLPI  199

Query  197  DNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTAL  256
            DNP+THLELTMVHEAMVLE +G  LA +E  + +RL  LL LLA L  PWG+A    TAL
Sbjct  200  DNPSTHLELTMVHEAMVLESSGRDLAWLELGSWLRLGALLGLLATLLAPWGVATEV-TAL  258

Query  257  DVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAA  309
             ++  V A+  K+A++  LLA  EVFLAK+RLFRVPELLAGSF+LALLAVTA+
Sbjct  259  GLVVAVGALVLKLALIGALLAAVEVFLAKVRLFRVPELLAGSFVLALLAVTAS  311


>gi|333983294|ref|YP_004512504.1| hydrogenase subunit [Methylomonas methanica MC09]
 gi|333807335|gb|AEG00005.1| hydrogenase subunit [Methylomonas methanica MC09]
Length=314

 Score =  239 bits (611),  Expect = 3e-61, Method: Compositional matrix adjust.
 Identities = 134/305 (44%), Positives = 197/305 (65%), Gaps = 4/305 (1%)

Query  1    MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGT  60
            M++L    Q    +  APL+ G  +  +   + R    LLQP+RDLLK + KQ +     
Sbjct  1    MNWLLAVIQTLLFVALAPLLSGWLKWCKCHLQNRNAPSLLQPYRDLLKLIRKQPVVAEHA  60

Query  61   TIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGT  120
            + +F  +P I+    +L A++ PL+A   P   SAD+  +VG        L LAG+D GT
Sbjct  61   SWIFTRSPYIIFSAMVLAASVVPLIALDLPTAASADVIVLVGFFAFARFFLALAGLDIGT  120

Query  121  SFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAF  180
            +FGGMG+SRE+TI++L EP +L+AVF L++ A + NL +L  + + + G V+  + V A 
Sbjct  121  AFGGMGSSREMTISSLAEPAMLMAVFTLTMTASTTNL-SLAITHVLNEGLVLRPSFVFAM  179

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
             AL++V +AETGR+PVDNP THLELTM+HEAM+LEY+G  LAL+EWA+ ++L +   L+A
Sbjct  180  FALILVAIAETGRVPVDNPTTHLELTMIHEAMILEYSGRHLALIEWASQLKLMLYGVLIA  239

Query  241  NLFLPWGIAGAAPTALDVL-TGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSF  299
            N+FLPWGI  A   +   L  G++A++ K+A LA+ LA  E  +AK+RLFRV E L+ ++
Sbjct  240  NIFLPWGI--AQDFSFHALGYGLLAISCKLAALAIFLAISETLVAKMRLFRVQEYLSFAY  297

Query  300  LLALL  304
            LL LL
Sbjct  298  LLGLL  302


>gi|144898670|emb|CAM75534.1| NADH dehydrogenase [Magnetospirillum gryphiswaldense MSR-1]
Length=315

 Score =  235 bits (599),  Expect = 8e-60, Method: Compositional matrix adjust.
 Identities = 139/287 (49%), Positives = 185/287 (65%), Gaps = 3/287 (1%)

Query  9    QIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAP  68
            QI  V+  APL+ G  R V+AR  GR G   +QP+RDL + L K+ I     + +F AAP
Sbjct  10   QIILVVALAPLITGYVRWVKARLNGRRGPSPIQPYRDLYRLLQKEAIVAHSASWIFRAAP  69

Query  69   VIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGAS  128
             +   +  L A I P   T   L P+ADL A+V LL +G     LAG+D GT+FGG+GAS
Sbjct  70   YVTFASVWLAACIVPTFTTNMVLAPAADLIALVALLAVGRFWTALAGMDVGTAFGGLGAS  129

Query  129  REITIAALVEPTILLAVFALSIPAGSANLGALVASTI-DHPGHVVSLAGVLAFVALVIVI  187
            RE+ IA+L EP +L+  F+LS+ +G+   G +VA  +  + G  VSL   LA  ALV+V 
Sbjct  130  REMLIASLAEPAMLMVTFSLSLISGTTAPGQIVAFVLAGNVGVEVSLG--LALAALVMVA  187

Query  188  VAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWG  247
            +AE GR+P+DNPATHLELTMVHEAMVLEY+G  LA++E A+ +RLT+ +AL+A LF PWG
Sbjct  188  IAENGRIPIDNPATHLELTMVHEAMVLEYSGRHLAMIEAASMVRLTLFIALIATLFAPWG  247

Query  248  IAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
            IA      L VL G+ A  AK  +LA  LA FE  +AK+R+FR  + 
Sbjct  248  IAQPGAGPLGVLVGMGAFLAKTFLLASALAVFETSIAKMRVFRYADF  294


>gi|91202881|emb|CAJ72520.1| similar to membrane-bound [NiFe]-hydrogenase-3, subunit D [Candidatus 
Kuenenia stuttgartiensis]
Length=312

 Score =  234 bits (596),  Expect = 2e-59, Method: Compositional matrix adjust.
 Identities = 127/295 (44%), Positives = 195/295 (67%), Gaps = 9/295 (3%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            APLV G   ++ A W+ R G  + QP+ +L+K L K  +     + +F+A P +V  + L
Sbjct  19   APLVKGFINKMEAYWQCRRGPSMFQPYYNLIKLLQKDVVVSETASWIFSATPYVVFVSIL  78

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
            +IA + P+++   PLD + D+  +V L  LG   L L+ +DTG++FGGMG SRE+TI+++
Sbjct  79   VIALLIPVLSAQVPLDFTGDIILIVYLFALGRFFLALSSLDTGSAFGGMGGSREMTISSM  138

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPV  196
             EP ++L++F +S+ AGS NL ++  + +++    ++ + +LAF AL IVIVAETGR+PV
Sbjct  139  AEPAMMLSIFTVSLTAGSTNLSSITGTLLNYKS--LNPSLLLAFAALAIVIVAETGRIPV  196

Query  197  DNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTAL  256
            DNP THLELTM+HE M+LE++G  LAL+EWA+ M+L +LL +L N FLPWGIA    T L
Sbjct  197  DNPFTHLELTMIHEGMILEFSGRYLALIEWASSMKLLLLLTILVNTFLPWGIA----TDL  252

Query  257  DVLTGVVAVA---AKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTA  308
                 +++ A    K+   A  +   E+  +KLRLFR+P LL  SF+L++LA+ +
Sbjct  253  TFPGMIISFAWYLVKIGFFAFAIVILELSFSKLRLFRIPNLLGTSFVLSVLAIIS  307


>gi|147919457|ref|YP_686803.1| hydrogenase, membrane subunit 3-like protein (EchB-like) [uncultured 
methanogenic archaeon RC-I]
 gi|110622199|emb|CAJ37477.1| hydrogenase, membrane subunit 3-like protein (EchB-like) [uncultured 
methanogenic archaeon RC-I]
Length=313

 Score =  233 bits (593),  Expect = 4e-59, Method: Compositional matrix adjust.
 Identities = 127/293 (44%), Positives = 193/293 (66%), Gaps = 4/293 (1%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            +PL+ G+ R+++A  + R GA + QP+ DL K   K+ +  +  + VF   P +     L
Sbjct  20   SPLITGVIRKLKALMQSRKGASVFQPYFDLYKLFRKESVVSSNASWVFHLTPYVCMAAVL  79

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
            +   + P+++T S L    DL  VV +L +    + L+ +DTG++FGGMG+SRE+TI+A+
Sbjct  80   VAVLMVPVISTTS-LSFMGDLIVVVYMLTMMRFFMALSALDTGSAFGGMGSSREMTISAI  138

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPV  196
             EPT+LLA+F +++ AG+ +LG +      +   ++  +  L F AL IV +AE  R+PV
Sbjct  139  AEPTMLLAIFTMALIAGTTSLGDISYQLSVNGLELIRPSLFLGFAALFIVTLAENARVPV  198

Query  197  DNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGA-APTA  255
            DNPATHLELTM+HE M+LEY+G +LAL+E ++ ++L + L +LAN+FLPWGIA + AP  
Sbjct  199  DNPATHLELTMIHEGMILEYSGKQLALMELSSMVKLALFLTILANVFLPWGIATSLAPAG  258

Query  256  LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTA  308
            L +  G+VA+  K+ I+A  +A  E  +AKLRLFR+P LL  SF LALLAV +
Sbjct  259  LAI--GLVALLVKILIMAGAIAYIESCMAKLRLFRLPNLLTVSFTLALLAVMS  309


>gi|344943802|ref|ZP_08783088.1| hydrogenase subunit [Methylobacter tundripaludum SV96]
 gi|344259460|gb|EGW19733.1| hydrogenase subunit [Methylobacter tundripaludum SV96]
Length=319

 Score =  230 bits (587),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 131/284 (47%), Positives = 188/284 (67%), Gaps = 4/284 (1%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            APL+ G  +  + R + R    +LQP+RDLLK   KQ +     + +F  AP I+   T+
Sbjct  22   APLLAGWVKCCKCRLQNRKAPSVLQPYRDLLKLTYKQPVVSEQASWLFTKAPYIIFSATV  81

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
            L A + PL+A   P   SAD+  +VG        L LAG+D GT+FGGMG+SRE+TI++L
Sbjct  82   LAATVVPLIAVDLPTSASADVIVMVGFFAFARFFLALAGLDVGTAFGGMGSSREMTISSL  141

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPV  196
             EP +L+A+F L++ A + NL   +A  ++  G V+  + V A  ALV+V VAETGR+PV
Sbjct  142  AEPAMLMAIFTLTMTASTTNLSLAIAHVLNE-GLVLRPSFVFALAALVLVAVAETGRIPV  200

Query  197  DNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTAL  256
            DNPATHLELTM+HEAM+LEY+G  LAL+EWA+ ++L +   L+AN+F PWGIA     ++
Sbjct  201  DNPATHLELTMIHEAMILEYSGRHLALIEWASQLKLMLYGVLIANIFFPWGIAET--LSI  258

Query  257  DVL-TGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSF  299
              L  G++A+  K+A+LAV+LA  E  +AK+RLFRV E L+ ++
Sbjct  259  QALGYGLLAIMGKLAVLAVVLAIAETLVAKMRLFRVQEYLSFAY  302


>gi|344341649|ref|ZP_08772566.1| hydrogenase subunit [Thiocapsa marina 5811]
 gi|343798403|gb|EGV16360.1| hydrogenase subunit [Thiocapsa marina 5811]
Length=321

 Score =  227 bits (579),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 134/271 (50%), Positives = 178/271 (66%), Gaps = 2/271 (0%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+VRAR + R GA + QP+R+L K L K+       + +F AAP +V   T L AA 
Sbjct  29   GWVRKVRARLQNRRGASVFQPYRELRKLLLKEARVAHTASPLFRAAPYVVFVATWLAAAT  88

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             PL+    P    AD+  + GLL L  V L LAG+D GT+FGGMGASRE+ I+AL EP +
Sbjct  89   VPLLTIDLPTAVVADIIVLAGLLALARVFLALAGMDVGTAFGGMGASREMMISALAEPAM  148

Query  142  LLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPAT  201
            L+AVF L++ A S NLG+++A  +     V+  + + AF  L +V +AETGR+PVDNP T
Sbjct  149  LMAVFTLAMTAHSTNLGSVIAHHLGD-AFVLRPSYLFAFAGLTLVALAETGRIPVDNPTT  207

Query  202  HLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTG  261
            HLELTMVHEAMVLEY+G  LAL+EWAA ++L +   L+AN+F PWG+A + P    +  G
Sbjct  208  HLELTMVHEAMVLEYSGRHLALMEWAAQIKLLLYGVLVANIFFPWGVA-SDPAPASLAMG  266

Query  262  VVAVAAKVAILAVLLATFEVFLAKLRLFRVP  292
            + AV  K+A+L   LA  E  LAK+RLFRVP
Sbjct  267  LAAVVLKLAVLGGALAAAETVLAKMRLFRVP  297


>gi|337266649|ref|YP_004610704.1| putative hydrogenase protein [Mesorhizobium opportunistum WSM2075]
 gi|336026959|gb|AEH86610.1| putative hydrogenase protein [Mesorhizobium opportunistum WSM2075]
Length=316

 Score =  227 bits (579),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 129/275 (47%), Positives = 181/275 (66%), Gaps = 5/275 (1%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+V+AR   R G  L+QP+RDLL+ + K+ +     + +F   P ++   T + AA+
Sbjct  24   GFVRKVKARLLRRQGPSLVQPYRDLLRLMRKEVVLADNASWLFRVTPYLIFAATWVAAAL  83

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  ATG     +ADL A+V LL      L LAG+D GTSFGG+G+SRE+ IA+L EP +
Sbjct  84   IPTFATGLTFSWAADLIAIVALLGSARFFLALAGMDVGTSFGGIGSSREVMIASLAEPAM  143

Query  142  LLAVFALSIPAGSANLGALVASTIDHP--GHVVSLAGVLAFVALVIVIVAETGRLPVDNP  199
            LL VF+L++ AG+  L   VA+ +  P  G  VSL   ++ +ALV+V VAE  R+PVDNP
Sbjct  144  LLIVFSLALVAGATQLST-VAAFMGSPQVGLRVSLG--MSLIALVMVAVAENARIPVDNP  200

Query  200  ATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVL  259
            ATHLELTMVHEAMVLEY+G  LA++E+AA ++L + ++L++ +FLPWG A        + 
Sbjct  201  ATHLELTMVHEAMVLEYSGRHLAMIEFAAFLKLLLYMSLISCVFLPWGAATTGAGLQSLA  260

Query  260  TGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
             GVVA   K+A+  VLLA FE  +AK+R+FRVP+ 
Sbjct  261  AGVVAYIGKLAVCGVLLAVFETAIAKMRVFRVPDF  295


>gi|182414277|ref|YP_001819343.1| hydrogenase, membrane subunit 3-like protein (EchB-like) [Opitutus 
terrae PB90-1]
 gi|177841491|gb|ACB75743.1| hydrogenase, membrane subunit 3-like protein (EchB-like) [Opitutus 
terrae PB90-1]
Length=314

 Score =  226 bits (577),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 137/297 (47%), Positives = 199/297 (68%), Gaps = 3/297 (1%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            APLV G+ +  +A+ + R G  + QP+ DLLK L K  +     + +F   PV++  T L
Sbjct  19   APLVSGVIKNWKAKLQNRRGPRVWQPYLDLLKFLRKDMVVSEHVSWIFGVTPVVLLLTAL  78

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
                + P++   +P+D   D  A+VGLL LG   L L+G+D  ++FGGMG+SRE+TI+A+
Sbjct  79   AAGLLVPMITVQAPMDLFGDALALVGLLALGRFCLALSGLDPASTFGGMGSSREMTISAV  138

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPV  196
             EP ++LA+FA+++ AGS NL  +V ++     + +  A  LAF A+ +V++AETGR+PV
Sbjct  139  AEPAMMLAIFAVALTAGSTNLSHIVQASEGFGWNFLDPAHALAFAAMFVVLLAETGRIPV  198

Query  197  DNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAA-PTA  255
            DNPATHLELTM+HEAM+LEY+G  LAL+EWA  ++  VL+ALLAN+F P G+AG A P A
Sbjct  199  DNPATHLELTMIHEAMLLEYSGRHLALIEWAVSVKQLVLMALLANIFFPLGLAGEATPAA  258

Query  256  LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANFF  312
            L +  G  AV  K+ +LA  +   E   AKLRLFRVP+LL+ +F+LA LA+ ++  F
Sbjct  259  LALGLGFFAV--KLLLLAGAIVLVEFTNAKLRLFRVPDLLSTAFILATLALVSSFLF  313


>gi|296446949|ref|ZP_06888884.1| NADH dehydrogenase [Methylosinus trichosporium OB3b]
 gi|296255516|gb|EFH02608.1| NADH dehydrogenase [Methylosinus trichosporium OB3b]
Length=317

 Score =  225 bits (574),  Expect = 6e-57, Method: Compositional matrix adjust.
 Identities = 131/286 (46%), Positives = 176/286 (62%), Gaps = 2/286 (0%)

Query  9    QIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAP  68
            Q+  V+  +PL+IG TR+V+AR   R G  LLQP+RDL++ + K+ I     + +F AAP
Sbjct  13   QMAFVLALSPLLIGFTRKVKARLLRRQGPPLLQPYRDLVRLMRKEVILAENASWLFRAAP  72

Query  69   VIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGAS  128
             ++  TT +  A+ P  ATG     +ADL  +  LL    + L LAG+D GTSFGG+G+S
Sbjct  73   YLIFATTWVATALTPTFATGLAFSWAADLIVITALLGSARLFLALAGMDVGTSFGGIGSS  132

Query  129  REITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIV  188
            REI  A+  EP +L+ VF +S+ AGS  L  +    +      VS A   A VAL IV +
Sbjct  133  REIMFASFAEPAMLMIVFIVSLIAGSTELSVVANHMLSSSELPVSFA--FALVALGIVAI  190

Query  189  AETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGI  248
            AE GR+PVDNPATHLELTMVHEAMVLEY+G  LA+VE AA M+L + ++L   +F PWG+
Sbjct  191  AENGRVPVDNPATHLELTMVHEAMVLEYSGRHLAVVELAAAMKLLLYVSLTICIFFPWGL  250

Query  249  AGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
            A        +    +    KVA+   LLA FEV  AK+R+FRVP  
Sbjct  251  APYEAGVGAMAASALGYVGKVAVAGFLLALFEVSTAKMRVFRVPNF  296


>gi|182679426|ref|YP_001833572.1| NADH dehydrogenase [Beijerinckia indica subsp. indica ATCC 9039]
 gi|182635309|gb|ACB96083.1| NADH dehydrogenase [Beijerinckia indica subsp. indica ATCC 9039]
Length=318

 Score =  225 bits (574),  Expect = 7e-57, Method: Compositional matrix adjust.
 Identities = 135/286 (48%), Positives = 183/286 (64%), Gaps = 9/286 (3%)

Query  13   VMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVA  72
            V+  AP + G  R+V+AR   R G  +LQP+RDL + + K+ +     + +F A P ++ 
Sbjct  17   VLCLAPALTGFVRKVKARLLRRRGPSILQPYRDLWRLMRKEVVLAENASWLFRAIPYLIF  76

Query  73   GTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREIT  132
              T + AA+ P  ATG     SADL AV  LL      L LAG+D GTSFGG+G+SRE+ 
Sbjct  77   SATWVAAALVPTFATGLLFSWSADLIAVTALLGSTRFFLALAGMDVGTSFGGIGSSREVM  136

Query  133  IAALVEPTILLAVFALSIPAGSANLGALVASTIDHP-GHVVSLAGVLAFVALVIVIVAET  191
            IA L EP +++ VF L++ AGS  L +L    +  P G  VSL   LA +ALV+V VAE 
Sbjct  137  IATLAEPAMIMIVFTLALLAGSTQLSSLAGFMLTSPVGLRVSLG--LALIALVMVAVAEN  194

Query  192  GRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGA  251
            GR+P+DNPATHLELTMVHEAM+LEY+G  LAL+E AA ++L + ++L+  +FLPWG+   
Sbjct  195  GRIPIDNPATHLELTMVHEAMLLEYSGRHLALIELAASLKLLLYVSLIGCVFLPWGL---  251

Query  252  APTALDVLTGVVAVAA---KVAILAVLLATFEVFLAKLRLFRVPEL  294
            +P   DV T +V V A   K+A    LLA FE  +AK+R+FRVPE 
Sbjct  252  SPPGADVSTRLVGVGAYGLKLAAGGFLLAFFETTVAKMRVFRVPEF  297


>gi|260575427|ref|ZP_05843426.1| NADH dehydrogenase [Rhodobacter sp. SW2]
 gi|259022347|gb|EEW25644.1| NADH dehydrogenase [Rhodobacter sp. SW2]
Length=320

 Score =  223 bits (568),  Expect = 3e-56, Method: Compositional matrix adjust.
 Identities = 130/280 (47%), Positives = 183/280 (66%), Gaps = 11/280 (3%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G+ R+V+AR   R GA L+QP+RDLL+ + KQ +     + +F  AP ++   T + AA+
Sbjct  26   GLVRKVKARLMRRRGASLIQPYRDLLRLMRKQVVLADNASWLFRVAPYLIFAATWVAAAL  85

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  ATG     +ADL A+V LL      L LAG+D GTSFGG+G+SRE+ I++L EP +
Sbjct  86   VPTFATGLHFSWTADLIAIVALLGSARFFLALAGMDVGTSFGGIGSSREMMISSLAEPAM  145

Query  142  LLAVFALSIPAGSANLGALVASTIDHP--GHVVSLAGVLAFVALVIVIVAETGRLPVDNP  199
            +L VF+L++ AGS  L   VA  +  P  G  VSL   +A VALVIV +AE  R+PVDNP
Sbjct  146  MLTVFSLALVAGSTQLST-VAEYMASPAVGLRVSLG--MALVALVIVALAENARIPVDNP  202

Query  200  ATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGI----AGAAPTA  255
            +THLELTMVHEAMVLEY+G  LA++E AA ++L + ++L+  +FLPWG+    +GA  +A
Sbjct  203  STHLELTMVHEAMVLEYSGRHLAMIEIAAALKLLLYISLIGCIFLPWGLVNSDSGAGLSA  262

Query  256  LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELL  295
               L  +     K+A+  V+LA FE  +AK+R+FRVP  +
Sbjct  263  --YLVAMALYGGKLALGGVVLAIFETSIAKMRVFRVPNFI  300


>gi|114775568|ref|ZP_01451136.1| hydrogenase subunit [Mariprofundus ferrooxydans PV-1]
 gi|114553679|gb|EAU56060.1| hydrogenase subunit [Mariprofundus ferrooxydans PV-1]
Length=315

 Score =  222 bits (566),  Expect = 5e-56, Method: Compositional matrix adjust.
 Identities = 133/304 (44%), Positives = 193/304 (64%), Gaps = 2/304 (0%)

Query  13   VMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVA  72
            ++V APL  G     +AR + R G G++QPWR+L K + K+ +     + +F  AP +V 
Sbjct  14   LIVLAPLAAGFVATCKARLQNRRGGGVMQPWRNLRKLIAKEVVMAEHASWIFRFAPYVVF  73

Query  73   GTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREIT  132
              T++ A+  P V   +PL  +AD+ A+V LL L    L LAG+D GT+FGGMGASRE+T
Sbjct  74   TATVMAASCVPAVLVNTPLSLTADVIALVALLALARFFLALAGMDIGTAFGGMGASREMT  133

Query  133  IAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETG  192
             +AL EP +L++VF LS+ A S NL  ++   ++ P  V+  +   A  A+V++ +AE G
Sbjct  134  FSALAEPAMLMSVFVLSLSAHSTNLTTMINHALNAPL-VLQPSLAFALAAMVMIAIAENG  192

Query  193  RLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAA  252
            R+P+DNP THLELTM+HEAM+LEY+G  LAL+EWAA ++L +   LL +LFLPWG+A  A
Sbjct  193  RIPIDNPTTHLELTMIHEAMILEYSGRHLALMEWAAMIKLLLFATLLIDLFLPWGMATDA  252

Query  253  PTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANFF  312
               L +   +    AK+  L ++LA  E  LAK+RLF  PE L+G+F++A L +      
Sbjct  253  -GILALTLALALWVAKLFGLLLMLALAETGLAKMRLFEAPEYLSGAFVIAFLGLLTHYML  311

Query  313  TVGA  316
             VGA
Sbjct  312  EVGA  315


>gi|83309309|ref|YP_419573.1| formate hydrogenlyase subunit 4 [Magnetospirillum magneticum 
AMB-1]
 gi|82944150|dbj|BAE49014.1| Formate hydrogenlyase subunit 4 [Magnetospirillum magneticum 
AMB-1]
Length=315

 Score =  222 bits (565),  Expect = 7e-56, Method: Compositional matrix adjust.
 Identities = 131/287 (46%), Positives = 178/287 (63%), Gaps = 3/287 (1%)

Query  9    QIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAP  68
            QI  V+  +PL+ G  R V++R  GR GA   QP+RD+ + L K+ +     + VF  AP
Sbjct  10   QIVLVVAISPLITGWVRLVKSRLNGRIGASPFQPYRDIYRLLQKEAVVAHSASWVFRVAP  69

Query  69   VIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGAS  128
             +  G   L A I P   T   L  +ADL A+V LL +      LAG+D GTSFGG+GAS
Sbjct  70   YVTFGAAWLAACIVPAFTTNLFLAQAADLIALVALLGVARFWTALAGMDVGTSFGGLGAS  129

Query  129  REITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHP-GHVVSLAGVLAFVALVIVI  187
            RE+ I++L EP +L+  F+LS+ +G+     ++A  +    G  VSL   LA  ALV+V 
Sbjct  130  REMMISSLAEPAMLMVTFSLSLISGTTAPAQIIAFVLSGGVGIEVSLG--LALAALVMVA  187

Query  188  VAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWG  247
            +AE GR+P+DNPATHLELTMVHEAMVLEY+G  LAL+E A  +RLT+ +AL+  LF PWG
Sbjct  188  IAENGRIPIDNPATHLELTMVHEAMVLEYSGRHLALMEGAGMVRLTLFMALIGGLFAPWG  247

Query  248  IAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
            +A     A+ VL G+ A  AK  +LA  L  FE  +AK+R+FR  + 
Sbjct  248  MAQPGGDAVAVLVGLAAFLAKCFVLATALGVFETSIAKMRVFRYADF  294


>gi|115522978|ref|YP_779889.1| respiratory-chain NADH dehydrogenase subunit 1 [Rhodopseudomonas 
palustris BisA53]
 gi|115516925|gb|ABJ04909.1| respiratory-chain NADH dehydrogenase, subunit 1 [Rhodopseudomonas 
palustris BisA53]
Length=319

 Score =  220 bits (561),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 130/284 (46%), Positives = 177/284 (63%), Gaps = 5/284 (1%)

Query  13   VMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVA  72
            V + APL+ G  R+V+AR   R G  LLQP+RDLL+ L K+ +     + +F   P +  
Sbjct  18   VFMLAPLLTGFVRKVKARLTRRQGPSLLQPYRDLLRLLRKEAVLADNASWLFRTTPYLTF  77

Query  73   GTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREIT  132
                + AA+ P  ATG   + +ADL  +V LL      L LAG+D GT+FGG+G+SRE+ 
Sbjct  78   AAIWVAAALVPTFATGLLFNWTADLIVIVALLGTARFFLALAGMDIGTAFGGIGSSREVM  137

Query  133  IAALVEPTILLAVFALSIPAGSANLGALVASTI--DHPGHVVSLAGVLAFVALVIVIVAE  190
            IAAL EP +LL VF +++ AGS  L   VA+ I     G  VSL   LA +ALV+V +AE
Sbjct  138  IAALAEPAMLLIVFGVALVAGSTQLST-VANFIASSQVGLRVSLG--LAMIALVMVALAE  194

Query  191  TGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAG  250
              R+PVDNP+THLELTMVHEAM+LEY+G  LA++E+ A ++L + ++L+  LF PWGIA 
Sbjct  195  NARIPVDNPSTHLELTMVHEAMILEYSGRHLAMIEFGAFLKLLLYVSLIGCLFFPWGIAI  254

Query  251  AAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
            A    L  + G      KV +   LLA FE   AK+R+FRVP+ 
Sbjct  255  AGDAPLSYVVGAGLYLLKVTVAGFLLALFETATAKMRVFRVPQF  298


>gi|344345383|ref|ZP_08776235.1| hydrogenase subunit [Marichromatium purpuratum 984]
 gi|343803003|gb|EGV20917.1| hydrogenase subunit [Marichromatium purpuratum 984]
Length=321

 Score =  220 bits (560),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 131/271 (49%), Positives = 178/271 (66%), Gaps = 4/271 (1%)

Query  21   IGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAA  80
            IG  R+V+AR   R GA +LQP+RDL K L K+       + +F  AP +V   T L AA
Sbjct  28   IGWVRKVKARLHNRRGASVLQPYRDLRKLLAKETRVAHTASPLFRLAPYVVFVATWLAAA  87

Query  81   IAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPT  140
              PLVA   P    AD+  +VGLL L    L LAG+D GT+FGGMGASRE+ +++L EP 
Sbjct  88   TVPLVARDLPTAQIADIIVLVGLLGLARFFLALAGMDVGTAFGGMGASREMMVSSLAEPA  147

Query  141  ILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPA  200
            +L+AVF L++ A S +L +++   +   G VV  + + AF ALV+V +AE+GR+PVDNP 
Sbjct  148  MLVAVFTLAMSAHSTSLSSVIGYHLTE-GFVVRPSYLFAFGALVLVALAESGRIPVDNPT  206

Query  201  THLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGA-APTALDVL  259
            THLELTM+HE M+LEY G  LAL+E AA ++L +   L+AN+F+PWGI  A AP AL  +
Sbjct  207  THLELTMIHEGMLLEYTGRHLALMELAAHLKLMLYGVLIANVFVPWGIGQAFAPVAL--V  264

Query  260  TGVVAVAAKVAILAVLLATFEVFLAKLRLFR  290
             G+ A+  K+A+L   LA  E  +AK+RLFR
Sbjct  265  LGLGAILLKLAVLGAALAIGETVVAKMRLFR  295


>gi|91978317|ref|YP_570976.1| respiratory-chain NADH dehydrogenase subunit 1 [Rhodopseudomonas 
palustris BisB5]
 gi|91684773|gb|ABE41075.1| respiratory-chain NADH dehydrogenase, subunit 1 [Rhodopseudomonas 
palustris BisB5]
Length=316

 Score =  219 bits (558),  Expect = 5e-55, Method: Compositional matrix adjust.
 Identities = 128/278 (47%), Positives = 176/278 (64%), Gaps = 11/278 (3%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+V+AR + R GA +LQP+RDL++ L K  +     + +F A P +      + AA+
Sbjct  24   GFIRKVKARLQRRRGASMLQPYRDLIRLLRKDVVLADNASWLFRATPYVTFAAIWVAAAL  83

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  ATG   + +ADL  VV LL      L LAG+D GTSFGG+G+SRE+ IAAL EP +
Sbjct  84   VPTFATGLMFNWTADLIVVVALLGTARFFLALAGMDIGTSFGGIGSSREVMIAALAEPAM  143

Query  142  LLAVFALSIPAGSANLGAL---VASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDN  198
            L+ VF +++ AGS +L  +   +AST    G  VSL   LA +ALV+V +AE  R+PVDN
Sbjct  144  LMIVFCVALVAGSTHLSTVANYIAST--EVGLRVSLG--LAMIALVMVALAENARIPVDN  199

Query  199  PATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIA--GAAPTAL  256
            P+THLELTMVHEAM+LEY+G  LA++E+ A ++L + ++L+  LF PWGI   GA P A 
Sbjct  200  PSTHLELTMVHEAMILEYSGRHLAMIEFGAQLKLLLYVSLIVCLFYPWGIGIFGAGPLA-  258

Query  257  DVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
              L G      K+ +   LLA FE   AK+R+FRVP+ 
Sbjct  259  -YLAGAALYMGKLTVAGFLLAVFETATAKMRVFRVPQF  295


>gi|312113078|ref|YP_004010674.1| NADH dehydrogenase [Rhodomicrobium vannielii ATCC 17100]
 gi|311218207|gb|ADP69575.1| NADH dehydrogenase [Rhodomicrobium vannielii ATCC 17100]
Length=321

 Score =  219 bits (557),  Expect = 6e-55, Method: Compositional matrix adjust.
 Identities = 138/306 (46%), Positives = 196/306 (65%), Gaps = 3/306 (0%)

Query  2    SYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTT  61
            S++A  AQ+  V+  AP V G+TR+V+AR   R G  L QP+RDLLK + K+ +     T
Sbjct  7    SFVAQGAQMFFVLAIAPAVTGITRKVKARLMRRRGPSLFQPYRDLLKLVRKESVLAPNAT  66

Query  62   IVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTS  121
              F +AP ++   T + AA+ P +A+G   + +AD+ A+V L+      L LA +D GT+
Sbjct  67   WFFRSAPYMIFAFTWVAAALVPTLASGLMFNWAADVVALVALIGAARALLALAAMDAGTA  126

Query  122  FGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHV-VSLAGVLAF  180
            FGG+G+SRE+ IA+L EP  LL    ++  AG+  L  +    I  P  + VS A  LAF
Sbjct  127  FGGIGSSREMMIASLAEPASLLVALTIAFAAGTTRLPEVAQFLITQPLEIRVSFA--LAF  184

Query  181  VALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLA  240
            VALVIV +AE  R+PVDNPATHLELTMVHEAMVLEY+G  LA++E A  ++LT+ ++L+ 
Sbjct  185  VALVIVAMAENARIPVDNPATHLELTMVHEAMVLEYSGRHLAMIEAAGHLKLTLYISLII  244

Query  241  NLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFL  300
             LFLP+G+A    +A     G+ +  AK+ + AV L  +EV +AK+R+FRV E L G+F 
Sbjct  245  CLFLPFGMAPFDGSAGAWAIGIGSYLAKLMLAAVALGVWEVSIAKMRVFRVSEFLGGAFT  304

Query  301  LALLAV  306
             A LA+
Sbjct  305  FAFLAI  310


>gi|56477809|ref|YP_159398.1| formate hydrogenlyase membrane subunit HyfD [Aromatoleum aromaticum 
EbN1]
 gi|56313852|emb|CAI08497.1| Formate hydrogenlyase membrane subunit subunit HyfD [Aromatoleum 
aromaticum EbN1]
Length=315

 Score =  218 bits (555),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 128/285 (45%), Positives = 177/285 (63%), Gaps = 2/285 (0%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G   Q RA  + R    LLQP+R L K   K+ +     + +F  AP ++ G   L   I
Sbjct  25   GWINQWRAWLQNRRAPSLLQPYRVLHKLFNKESVVAETASPLFRVAPYVMFGCMALACGI  84

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
            AP ++T  PL P+AD  A+VGL  L  V ++LA +D GTSFG +GA RE+ +  L EP +
Sbjct  85   APTLSTDLPLAPAADAIALVGLFALARVFISLAAMDIGTSFGTLGARREMLVGFLAEPAL  144

Query  142  LLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPAT  201
            L+ +F+ S+   S +L  +V  T+ H    +  +  +A VA  +V +AE  R+PVDNPAT
Sbjct  145  LMVLFSASLITQSTSLAKIV-ETLAHEPFAIYPSLAVAGVAFTMVSLAENARVPVDNPAT  203

Query  202  HLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTG  261
            HLELTM+HEA++LEY+G  LALVEWAA ++L     +   LF+PWGIA A  T L +L  
Sbjct  204  HLELTMIHEALILEYSGRHLALVEWAASLKLFAYSCIGLALFVPWGIAEAG-TPLTILFA  262

Query  262  VVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAV  306
            +  + AK+AI  VLLA  E   AK+RLFRVPE LA +FLLA++A+
Sbjct  263  IPVLVAKLAIGGVLLALIETINAKMRLFRVPEFLATAFLLAVIAL  307


>gi|198283915|ref|YP_002220236.1| formate hydrogenlyase membrane subunit HyfD [Acidithiobacillus 
ferrooxidans ATCC 53993]
 gi|218665331|ref|YP_002426549.1| hydrogenase-4, C subunit [Acidithiobacillus ferrooxidans ATCC 
23270]
 gi|198248436|gb|ACH84029.1| formate hydrogenlyase membrane subunit subunit HyfD [Acidithiobacillus 
ferrooxidans ATCC 53993]
 gi|218517544|gb|ACK78130.1| hydrogenase-4, C subunit [Acidithiobacillus ferrooxidans ATCC 
23270]
Length=313

 Score =  216 bits (550),  Expect = 4e-54, Method: Compositional matrix adjust.
 Identities = 140/309 (46%), Positives = 190/309 (62%), Gaps = 4/309 (1%)

Query  8    AQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAA  67
            AQ+  V   APL  GM R +RA  + R  AG  Q +RDL +   K+ +   GT+ +F  A
Sbjct  9    AQVLLVAFLAPLFAGMLRALRAILQNRRPAGCWQNYRDLYRLFHKESLQAEGTSWLFRFA  68

Query  68   PVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGA  127
            P  + G   L AAI P++ATG PL P+AD+ A+VGL  L  V   LA +DTGT F  +GA
Sbjct  69   PYGIFGAFCLAAAIIPILATGLPLAPAADVIALVGLFALARVFQVLAAMDTGTPFATLGA  128

Query  128  SREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVI  187
             RE+ IA L EP +L  +F  S+ + S +L  +VA  ++     +  +   A  A  IV+
Sbjct  129  HREMLIAGLAEPALLATLFTASLLSRSTSLSVIVAH-LEQLRFALHPSMAFAATAFFIVL  187

Query  188  VAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWG  247
            +AE  R+PVDNPATHLELTM+HEAM+LEY+G  LAL+EW A ++LT+ +A+   LFLPWG
Sbjct  188  LAENARIPVDNPATHLELTMIHEAMLLEYSGRHLALMEWGAQIKLTLYVAIGIALFLPWG  247

Query  248  IAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVT  307
            I   A  A+  +T  V +  K A  AV+LA  E  LAKLRLFR PE +A +FLL ++ + 
Sbjct  248  IVPTAEVAMLPMTLPV-LLLKFASAAVILALIETLLAKLRLFRAPEFMATAFLLGVIGLL  306

Query  308  AANFFTVGA  316
               FF +GA
Sbjct  307  --TFFMLGA  313


>gi|90422449|ref|YP_530819.1| respiratory-chain NADH dehydrogenase subunit 1 [Rhodopseudomonas 
palustris BisB18]
 gi|90104463|gb|ABD86500.1| respiratory-chain NADH dehydrogenase, subunit 1 [Rhodopseudomonas 
palustris BisB18]
Length=316

 Score =  216 bits (549),  Expect = 5e-54, Method: Compositional matrix adjust.
 Identities = 128/277 (47%), Positives = 173/277 (63%), Gaps = 9/277 (3%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+V+AR   R GA + QP+RDLL+ L K+ +     + +F A P +      + AA+
Sbjct  24   GFIRKVKARLMRRKGASIFQPYRDLLRLLRKEVVLADNASWLFRATPYLTFAAIWVAAAL  83

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  ATG   + +ADL  +V LL      L LAG+D GT+FGG+G+SRE+ IAAL EP +
Sbjct  84   VPTFATGLLFNWTADLIVIVALLGTARFFLALAGMDVGTAFGGLGSSREVMIAALAEPAM  143

Query  142  LLAVFALSIPAGSANLGALVASTI--DHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNP  199
            LL VF +++ AGS  L   VA+ I     G  VSL   +A +ALVIV +AE  R+PVDNP
Sbjct  144  LLIVFCVALVAGSTQLST-VANFIASSQVGLRVSLG--MAMIALVIVALAENARIPVDNP  200

Query  200  ATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIA--GAAPTALD  257
            +THLELTMVHEAM+LEY+G  LAL+E+ A ++L + ++L+  LF PW IA  GA P  L 
Sbjct  201  STHLELTMVHEAMILEYSGRHLALIEFGAFLKLLLYISLIGCLFFPWEIAVFGAGP--LS  258

Query  258  VLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
             + G      KV +   LLA FE   AK+R+FRVP+ 
Sbjct  259  YVIGAGMYLLKVTVAGFLLAVFETATAKMRVFRVPQF  295


>gi|325288315|ref|YP_004264496.1| respiratory-chain NADH dehydrogenase subunit 1 [Syntrophobotulus 
glycolicus DSM 8271]
 gi|324963716|gb|ADY54495.1| respiratory-chain NADH dehydrogenase subunit 1 [Syntrophobotulus 
glycolicus DSM 8271]
Length=314

 Score =  215 bits (547),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 108/272 (40%), Positives = 170/272 (63%), Gaps = 1/272 (0%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G+ ++++A ++ R G  + QP+ DL K L K+ +    T+ +F A P +  G  L+IA +
Sbjct  23   GIIKKIKAFFQNRRGPRICQPYYDLYKYLQKETVVSEHTSWIFTATPYLYFGAMLVIAML  82

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P V    PL    D+  +V LL L    L LAG+D G++FGGM +SRE+ ++++VEP +
Sbjct  83   VPAVTVAGPLAFGGDIILIVYLLALARFFLALAGLDAGSAFGGMASSREMALSSVVEPAM  142

Query  142  LLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPAT  201
            +L +F +S+ AG+ NL  +V         V + +  ++F+AL +V +AETGR+PVDNP T
Sbjct  143  MLPLFTVSLAAGTTNLSQIVTEVAKTGPAVFTPSHFISFLALFVVAIAETGRIPVDNPDT  202

Query  202  HLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTG  261
            HLELTM+HE M+LEY+G  LAL+   A ++  ++   LAN+F PWGIA +   A  V  G
Sbjct  203  HLELTMIHEGMLLEYSGKPLALLTLGAYLKQVLIFTFLANIFFPWGIAFSL-NAASVFGG  261

Query  262  VVAVAAKVAILAVLLATFEVFLAKLRLFRVPE  293
            ++    K+  L +++A  E  ++K+RLF+VPE
Sbjct  262  ILFFLGKLVFLGIVMAVIETSMSKMRLFKVPE  293


>gi|89902060|ref|YP_524531.1| respiratory-chain NADH dehydrogenase subunit 1 [Rhodoferax ferrireducens 
T118]
 gi|89346797|gb|ABD71000.1| respiratory-chain NADH dehydrogenase, subunit 1 [Rhodoferax ferrireducens 
T118]
Length=316

 Score =  214 bits (545),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 128/307 (42%), Positives = 189/307 (62%), Gaps = 5/307 (1%)

Query  1    MSYLAGAAQIGGV---MVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITP  57
            MS+L   +Q+  +   +V APL+ G   Q RAR + ++   LLQP+R L K   K+ +  
Sbjct  1    MSWLGLLSQLMAIVMALVLAPLLTGWVNQWRARLQNKSAPNLLQPYRVLHKLFNKESVLA  60

Query  58   AGTTIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGID  117
               + +F  AP IV G  LL +AI P ++T  PL P+AD  A+VGL  L  V ++LA +D
Sbjct  61   EHASPLFRMAPYIVFGCMLLASAIIPTLSTDLPLSPAADAIALVGLFALARVFISLAAMD  120

Query  118  TGTSFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGV  177
             GT+FG +GA RE+ +  L EP +L+ +F  S+ + S +L  +V  T+ H    +  + +
Sbjct  121  VGTAFGSLGARREMLVGFLAEPALLMVLFCASMISRSTSLTTIV-ETLAHRELAIYPSLL  179

Query  178  LAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLA  237
            +A VA  +V +AE  R+PVDNP THLELTM+HE+M+LEY+G  LAL+EWAA ++L     
Sbjct  180  VAGVAFTMVSLAENARVPVDNPDTHLELTMIHESMILEYSGRHLALLEWAASLKLFAYSC  239

Query  238  LLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAG  297
            +   LF PWG+A  A   L +L  +  +  K+A+  VL+A  E   AK+R+FRVPE L  
Sbjct  240  IGLALFFPWGVA-EAHAPLALLLALPVLVIKLALGGVLMALIETLSAKMRIFRVPEFLGT  298

Query  298  SFLLALL  304
            +FLLA++
Sbjct  299  AFLLAVI  305


>gi|27381451|ref|NP_772980.1| hydrogenlyase component [Bradyrhizobium japonicum USDA 110]
 gi|27354619|dbj|BAC51605.1| hycC [Bradyrhizobium japonicum USDA 110]
Length=318

 Score =  213 bits (542),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 125/278 (45%), Positives = 175/278 (63%), Gaps = 11/278 (3%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+++AR   R GA + QP+ DLL+ L K+ +     + +F   P +      + AA+
Sbjct  26   GFVRKIKARLVRRQGASVFQPYLDLLRLLRKEVVLADNASWLFRVTPYVTFAAIWVAAAL  85

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  ATG   + +ADL A+V LL      L LAG+D GTSFGG+G+SRE+ IAAL EP +
Sbjct  86   VPTFATGLLFNWTADLIAIVALLGSARFFLALAGMDVGTSFGGIGSSREVMIAALAEPAM  145

Query  142  LLAVFALSIPAGSANLGA---LVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDN  198
            LL VF  ++ AGS  L      +AS+  + G  VSL   +A +AL++V +AE  R+PVDN
Sbjct  146  LLFVFCTALIAGSTQLSTVANFMASS--YVGLRVSLG--MAMIALIMVALAENARIPVDN  201

Query  199  PATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIA--GAAPTAL  256
            PATHLELTMVHEAMVLEY+G  LA++E+ A ++L + ++L+A +FLPW IA  G  P + 
Sbjct  202  PATHLELTMVHEAMVLEYSGRHLAMIEFGAFLKLLLYVSLIACVFLPWKIAVFGTGPFSY  261

Query  257  DVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
             +  G VA   K+A+    LA FE   AK+R+FRVP+ 
Sbjct  262  AI--GAVAYLVKLAVAGFFLALFETATAKMRVFRVPQF  297


>gi|86748386|ref|YP_484882.1| respiratory-chain NADH dehydrogenase, subunit 1 [Rhodopseudomonas 
palustris HaA2]
 gi|86571414|gb|ABD05971.1| Respiratory-chain NADH dehydrogenase, subunit 1 [Rhodopseudomonas 
palustris HaA2]
Length=316

 Score =  212 bits (540),  Expect = 5e-53, Method: Compositional matrix adjust.
 Identities = 122/276 (45%), Positives = 172/276 (63%), Gaps = 7/276 (2%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+V+AR + R G  LLQP+RDL++ L K+ +     + +F A P +      + AA+
Sbjct  24   GFIRKVKARLQRRRGPSLLQPYRDLIRLLRKEVVLADNASWLFRATPYVTFAAIWVAAAL  83

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  ATG   + +ADL  +V LL      L LAG+D GTSFGG+G+SRE+ IAAL EP +
Sbjct  84   VPTFATGLLFNWTADLIVIVALLGTARFFLALAGMDVGTSFGGIGSSREVMIAALAEPAM  143

Query  142  LLAVFALSIPAGSANLGAL---VASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDN  198
            L+ VF +++ AG+ +L  +   +AST    G  VSL   LA +ALV+V +AE  R+P+DN
Sbjct  144  LMIVFCVALVAGTTHLSTVANYIAST--AVGLRVSLG--LAMIALVMVALAENARIPIDN  199

Query  199  PATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDV  258
            P+THLELTMVHEAM+LEY+G  LA++E+ A ++L + ++L+  LF PWGI          
Sbjct  200  PSTHLELTMVHEAMILEYSGRHLAMIEYGAQLKLLLYVSLIVCLFYPWGIGVFGAGPAAY  259

Query  259  LTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPEL  294
            L G      K+ I   LLA FE   AK+R+FRVP+ 
Sbjct  260  LAGAALYLFKITIAGFLLAVFETATAKMRVFRVPQF  295


>gi|343917163|gb|EGV27972.1| hydrogenase subunit [Thiorhodococcus drewsii AZ1]
Length=315

 Score =  212 bits (539),  Expect = 6e-53, Method: Compositional matrix adjust.
 Identities = 130/272 (48%), Positives = 180/272 (67%), Gaps = 2/272 (0%)

Query  21   IGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAA  80
            +G  R+V+AR + R GA + QP+ DL K L K+       + +F  AP IV   T L AA
Sbjct  22   VGWVRKVKARLQNRRGASVFQPYADLRKLLIKETRVAHTASELFRVAPYIVFVATWLAAA  81

Query  81   IAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPT  140
              PLVA   P+   AD+  +VGLL L    L LAG+D GT+FGGMGASRE+ ++AL EP 
Sbjct  82   TVPLVALDLPIAAVADIIVLVGLLALARFFLALAGMDAGTAFGGMGASREMLVSALAEPA  141

Query  141  ILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPA  200
            +L+AVF L++ A S +L +++A  +   G ++  + + AF ALV+V +AE GR+PVDNP+
Sbjct  142  MLMAVFTLAMTAHSTSLQSVMAHHLA-DGFLLRPSYLFAFGALVLVALAECGRIPVDNPS  200

Query  201  THLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLT  260
            THLELTM+HEAM+LEY+G  LAL+EWAA ++L +   L+ N+F PWG+ GA    L + +
Sbjct  201  THLELTMIHEAMLLEYSGRHLALMEWAAQIKLLLYGVLIVNVFFPWGV-GANFGVLALGS  259

Query  261  GVVAVAAKVAILAVLLATFEVFLAKLRLFRVP  292
            G+  V  K+ +L  LLA  E  LAK+RLFRVP
Sbjct  260  GLAVVLLKLLVLGALLAAGETVLAKMRLFRVP  291


>gi|91786819|ref|YP_547771.1| respiratory-chain NADH dehydrogenase subunit 1 [Polaromonas sp. 
JS666]
 gi|91696044|gb|ABE42873.1| respiratory-chain NADH dehydrogenase, subunit 1 [Polaromonas 
sp. JS666]
Length=315

 Score =  212 bits (539),  Expect = 7e-53, Method: Compositional matrix adjust.
 Identities = 125/289 (44%), Positives = 177/289 (62%), Gaps = 4/289 (1%)

Query  17   APLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTL  76
            APL+ G   Q RA  + ++   L QP+R L K   K+ +     + +F  AP +V G  +
Sbjct  20   APLLTGWVNQWRAWLQNKSAPSLWQPYRMLHKLFNKESMVADSASRLFRIAPYVVFGCMV  79

Query  77   LIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAAL  136
            L  +I P V+T  PL  +AD  A+VGL  L  V ++LA +D GT+FG MGA RE+ I  L
Sbjct  80   LACSIIPTVSTDLPLATAADAIALVGLFALARVFISLAAMDIGTAFGTMGARREMLIGFL  139

Query  137  VEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPV  196
             EP +L+ +F+ S+ + S +L  +V  T+ H    +      A VA  +V +AE  R+PV
Sbjct  140  AEPALLMVLFSASLISKSTSLTTIV-ETLAHRELAIYPGLAFAGVAFTMVSLAENARVPV  198

Query  197  DNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGA-APTA  255
            DNPATHLELTM+HEA++LEY+G  LAL+EWAA ++L     +   LF PWG+A A AP A
Sbjct  199  DNPATHLELTMIHEALILEYSGRHLALIEWAASLKLFAYSCIGLALFFPWGVAEAQAPLA  258

Query  256  LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALL  304
            +  L  +  +  K+A+   LLA  E F AK+R+FRVPE LA +FLLA++
Sbjct  259  M--LLALPVLVFKLAVGGFLLAALEAFSAKMRIFRVPEFLATAFLLAVI  305


>gi|148260399|ref|YP_001234526.1| formate hydrogenlyase subunit 4-like protein [Acidiphilium cryptum 
JF-5]
 gi|326403591|ref|YP_004283673.1| putative NADH dehydrogenase [Acidiphilium multivorum AIU301]
 gi|146402080|gb|ABQ30607.1| Formate hydrogenlyase subunit 4-like protein [Acidiphilium cryptum 
JF-5]
 gi|325050453|dbj|BAJ80791.1| putative NADH dehydrogenase [Acidiphilium multivorum AIU301]
Length=318

 Score =  212 bits (539),  Expect = 8e-53, Method: Compositional matrix adjust.
 Identities = 124/277 (45%), Positives = 179/277 (65%), Gaps = 7/277 (2%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+V+AR + RAG  LLQ +RDL + + K+ + P  ++ +F  +P ++   T + AA+
Sbjct  26   GFVRKVKARLQRRAGPPLLQVYRDLARLVAKEAVVPEASSWLFRVSPYVIFAATWVAAAL  85

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  AT      S DL  +  LL        LA +D+GT+FGG+GASRE  +A+L EP +
Sbjct  86   VPEFATNLQFSWSGDLIVIAALLGSARFFQMLAALDSGTAFGGIGASREAMLASLAEPAM  145

Query  142  LLAVFALSIPAGSANLGALVASTIDHPG-HVVSLAGVLAFVALVIVIVAETGRLPVDNPA  200
            L+ VF +++ AG++ L A+  +T  H G   + L+  L  VALV+V + ETGR PVDNPA
Sbjct  146  LMIVFTVALVAGTSQLSAI--ATFMHSGAEGLRLSLALGLVALVMVGLTETGRFPVDNPA  203

Query  201  THLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIA--GAAPTALDV  258
            THLELTMVHEAMVLEY+G  LAL+E A  MRL + ++L+A +F P+GIA  GA P +L +
Sbjct  204  THLELTMVHEAMVLEYSGRHLALIELAGAMRLLLYMSLIACIFAPFGIAPPGAGPASLAL  263

Query  259  LTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELL  295
              G+++ A K+   AV LA FE  +AK+R+FR+P  +
Sbjct  264  --GLLSYAGKLGAGAVALAGFETTIAKMRVFRIPNFV  298


>gi|299132785|ref|ZP_07025980.1| respiratory-chain NADH dehydrogenase, subunit 1 [Afipia sp. 1NLS2]
 gi|298592922|gb|EFI53122.1| respiratory-chain NADH dehydrogenase, subunit 1 [Afipia sp. 1NLS2]
Length=317

 Score =  210 bits (534),  Expect = 3e-52, Method: Compositional matrix adjust.
 Identities = 121/278 (44%), Positives = 176/278 (64%), Gaps = 10/278 (3%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G+TR+++AR + R G  +LQP+RDL +  GK  +    ++ +F  AP ++   T + AA+
Sbjct  26   GVTRKMKARLQRRIGPPILQPYRDLRRLFGKDVVLADNSSWLFRVAPYLIFAATWVAAAL  85

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P   TG       DL A+V LL        +A +DTGTSFGG+GASRE+ IA+L EP +
Sbjct  86   VPTFQTGLLFSWVGDLIAIVALLGTARFVQAVAALDTGTSFGGIGASREVMIASLAEPAM  145

Query  142  LLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPAT  201
            ++ VF +++ AGS  L  + A   D  G  VSLA  +A VAL+IV +AE  R+PVDNP+T
Sbjct  146  IMVVFTVALVAGSTQLSTIAAFMADAGGLRVSLA--MALVALIIVALAENARIPVDNPST  203

Query  202  HLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGI----AGAAPTALD  257
            HLE+TMVHEAM LEY+G  LA++E AA ++L + ++++A +F P+G+    AG    A+ 
Sbjct  204  HLEVTMVHEAMALEYSGRHLAMIELAASLKLLLYISIIACIFFPFGLITDGAGLPAHAIS  263

Query  258  VLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELL  295
                + A   KV +  +LLAT E  +AK+R+FRVP LL
Sbjct  264  ----LAAYLLKVIVAGLLLATLETVIAKMRVFRVPNLL  297


>gi|339834212|gb|EGQ61992.1| hydrogenase-4, C subunit [Acidithiobacillus sp. GGI-221]
Length=286

 Score =  209 bits (531),  Expect = 7e-52, Method: Compositional matrix adjust.
 Identities = 131/283 (47%), Positives = 176/283 (63%), Gaps = 2/283 (0%)

Query  19   LVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLI  78
            L  GM R +RA  + R  AG  Q +RDL +   K+ +   GT+ +F  AP  + G   L 
Sbjct  1    LFAGMLRALRAILQNRRPAGCWQNYRDLYRLFHKESLQAEGTSWLFRFAPYGIFGAFCLA  60

Query  79   AAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVE  138
            AAI P++ATG PL P+AD+ A+VGL  L  V   LA +DTGT F  +GA RE+ IA L E
Sbjct  61   AAIIPILATGLPLAPAADVIALVGLFALARVFQVLAAMDTGTPFATLGAHREMLIAGLAE  120

Query  139  PTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDN  198
            P +L  +F  S+ + S +L  +VA  ++     +  +   A  A  IV++AE  R+PVDN
Sbjct  121  PALLATLFTASLLSRSTSLSVIVAH-LEQLRFALHPSMAFAATAFFIVLLAENARIPVDN  179

Query  199  PATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDV  258
            PATHLELTM+HEAM+LEY+G  LAL+EW A ++LT+ +A+   LFLPWGI   A  A+  
Sbjct  180  PATHLELTMIHEAMLLEYSGRHLALMEWGAQIKLTLYVAIGIALFLPWGIVPTAEVAMLP  239

Query  259  LTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLL  301
            +T  V +  K A  AV+LA  E  LAKLRLFR PE +A +FLL
Sbjct  240  MTLPV-LLLKFASAAVILALIETLLAKLRLFRAPEFMATAFLL  281


>gi|338980410|ref|ZP_08631686.1| Formate hydrogenlyase subunit 4-like protein [Acidiphilium sp. 
PM]
 gi|338208673|gb|EGO96516.1| Formate hydrogenlyase subunit 4-like protein [Acidiphilium sp. 
PM]
Length=318

 Score =  208 bits (529),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 123/277 (45%), Positives = 178/277 (65%), Gaps = 7/277 (2%)

Query  22   GMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAI  81
            G  R+V+AR + RAG  LLQ +RDL + + K+ + P  ++ +F  +P ++   T + AA+
Sbjct  26   GFVRKVKARLQRRAGPPLLQVYRDLARLVAKEAVVPEASSWLFRVSPYVIFAATWVAAAL  85

Query  82   APLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTI  141
             P  AT      S DL  +  LL        LA +D+GT+FGG+GASRE  +A+L EP +
Sbjct  86   VPEFATNLQFSWSGDLIVIAALLGSARFFQMLAALDSGTAFGGIGASREAMLASLAEPAM  145

Query  142  LLAVFALSIPAGSANLGALVASTIDHPG-HVVSLAGVLAFVALVIVIVAETGRLPVDNPA  200
            L+ VF +++ AG++ L A+  +T  H G   + L+  L  VALV+V + ETGR PV NPA
Sbjct  146  LMIVFTVALVAGTSQLSAI--ATFMHSGAEGLRLSLALGLVALVMVGLTETGRFPVANPA  203

Query  201  THLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIA--GAAPTALDV  258
            THLELTMVHEAMVLEY+G  LAL+E A  MRL + ++L+A +F P+GIA  GA P +L +
Sbjct  204  THLELTMVHEAMVLEYSGRHLALIELAGAMRLLLYMSLIACIFAPFGIAPPGAGPASLAL  263

Query  259  LTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELL  295
              G+++ A K+   AV LA FE  +AK+R+FR+P  +
Sbjct  264  --GLLSYAGKLGAGAVALAGFETTIAKMRVFRIPNFV  298



Lambda     K      H
   0.325    0.138    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 549222890922




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40