BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0086

Length=488
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607228|ref|NP_214600.1|  hydrogenase HycQ [Mycobacterium tub...   920    0.0   
gi|254366542|ref|ZP_04982586.1|  hydrogenase hycQ [Mycobacterium ...   920    0.0   
gi|31791264|ref|NP_853757.1|  hydrogenase HycQ [Mycobacterium bov...   918    0.0   
gi|308373882|ref|ZP_07433990.2|  hydrogenase hycQ [Mycobacterium ...   914    0.0   
gi|289748554|ref|ZP_06507932.1|  LOW QUALITY PROTEIN: hydrogenase...   788    0.0   
gi|340625121|ref|YP_004743573.1|  putative hydrogenase HYCQ [Myco...   764    0.0   
gi|118617495|ref|YP_905827.1|  hydrogenase HycQ [Mycobacterium ul...   645    0.0   
gi|183981672|ref|YP_001849963.1|  hydrogenase HycQ [Mycobacterium...   644    0.0   
gi|240169558|ref|ZP_04748217.1|  hydrogenase HycQ [Mycobacterium ...   636    2e-180
gi|342862429|ref|ZP_08719069.1|  putative hydrogenase HycQ [Mycob...   630    1e-178
gi|296166647|ref|ZP_06849073.1|  hydrogenase-4, F subunit [Mycoba...   627    1e-177
gi|118462524|ref|YP_884228.1|  hydrogenase-4, F subunit, putative...   592    5e-167
gi|333991246|ref|YP_004523860.1|  hydrogenase HycQ [Mycobacterium...   543    3e-152
gi|298527478|ref|ZP_07014887.1|  hydrogenase [Mycobacterium tuber...   524    1e-146
gi|336178231|ref|YP_004583606.1|  NADH dehydrogenase (quinone) [F...   373    4e-101
gi|317126122|ref|YP_004100234.1|  NADH/Ubiquinone/plastoquinone (...   372    1e-100
gi|119718685|ref|YP_925650.1|  NADH dehydrogenase (quinone) [Noca...   313    5e-83 
gi|258653158|ref|YP_003202314.1|  NADH/Ubiquinone/plastoquinone (...   311    2e-82 
gi|269128895|ref|YP_003302265.1|  NADH/Ubiquinone/plastoquinone (...   308    2e-81 
gi|325578548|ref|ZP_08148648.1|  hydrogenase-4 component F [Haemo...   291    1e-76 
gi|258593563|emb|CBE69904.1|  Hydrogenase-4 component F [NC10 bac...   285    2e-74 
gi|338812157|ref|ZP_08624346.1|  NADH dehydrogenase (quinone) [Ac...   281    2e-73 
gi|343518711|ref|ZP_08755701.1|  hydrogenase 4 subunit F [Haemoph...   278    1e-72 
gi|91202883|emb|CAJ72522.1|  strongly similar to membrane-bound [...   277    4e-72 
gi|260913687|ref|ZP_05920163.1|  hydrogenase subunit [Pasteurella...   275    2e-71 
gi|251792880|ref|YP_003007606.1|  hydrogenase-4 subunit F [Aggreg...   275    2e-71 
gi|293392058|ref|ZP_06636392.1|  hydrogenase-4 component F [Aggre...   274    2e-71 
gi|261868402|ref|YP_003256324.1|  hydrogenase-4 subunit F [Aggreg...   273    4e-71 
gi|345430346|ref|YP_004823467.1|  hydrogenase 4, membrane subunit...   272    1e-70 
gi|312110877|ref|YP_003989193.1|  NADH/Ubiquinone/plastoquinone (...   271    2e-70 
gi|220929110|ref|YP_002506019.1|  NADH/Ubiquinone/plastoquinone (...   269    8e-70 
gi|147919459|ref|YP_686801.1|  hydrogenase, membrane subunit 1-li...   268    2e-69 
gi|341948990|gb|EGT75605.1|  hydrogenase-4 component F [Haemophil...   265    9e-69 
gi|341956341|gb|EGT82771.1|  hydrogenase-4 component F [Haemophil...   265    1e-68 
gi|341949807|gb|EGT76406.1|  hydrogenase-4 component F [Haemophil...   265    2e-68 
gi|238749932|ref|ZP_04611436.1|  Hydrogenase-4 component F [Yersi...   265    2e-68 
gi|326202173|ref|ZP_08192043.1|  NADH/Ubiquinone/plastoquinone (c...   264    2e-68 
gi|83591011|ref|YP_431020.1|  hydrogenase 4 subunit F [Moorella t...   264    2e-68 
gi|325288317|ref|YP_004264498.1|  NADH dehydrogenase (quinone) [S...   263    4e-68 
gi|342903801|ref|ZP_08725605.1|  hydrogenase-4 component F [Haemo...   263    5e-68 
gi|334341775|ref|YP_004546755.1|  NADH/Ubiquinone/plastoquinone (...   263    5e-68 
gi|238793447|ref|ZP_04637072.1|  Hydrogenase-4 component F [Yersi...   262    8e-68 
gi|89074817|ref|ZP_01161271.1|  NADH dehydrogenase subunit N [Pho...   261    2e-67 
gi|258514104|ref|YP_003190326.1|  NADH/Ubiquinone/plastoquinone (...   258    1e-66 
gi|341955809|gb|EGT82259.1|  hydrogenase-4 component F [Haemophil...   258    1e-66 
gi|90426042|ref|YP_534412.1|  hydrogenase 4 subunit F [Rhodopseud...   258    2e-66 
gi|94313590|ref|YP_586799.1|  hydrogenase 4 subunit F [Cupriavidu...   258    2e-66 
gi|238788861|ref|ZP_04632652.1|  Hydrogenase-4 component F [Yersi...   256    5e-66 
gi|238784031|ref|ZP_04628046.1|  Hydrogenase-4 component F [Yersi...   256    9e-66 
gi|139437058|ref|ZP_01771218.1|  Hypothetical protein COLAER_0019...   255    1e-65 


>gi|15607228|ref|NP_214600.1| hydrogenase HycQ [Mycobacterium tuberculosis H37Rv]
 gi|15839467|ref|NP_334504.1| NADH-ubiquinone oxidoreductase, putative [Mycobacterium tuberculosis 
CDC1551]
 gi|148659848|ref|YP_001281371.1| putative hydrogenase HycQ [Mycobacterium tuberculosis H37Ra]
 55 more sequence titles
 Length=488

 Score =  920 bits (2379),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 488/488 (100%), Positives = 488/488 (100%), Gaps = 0/488 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG
Sbjct  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL
Sbjct  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG
Sbjct  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST
Sbjct  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL
Sbjct  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI
Sbjct  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480

Query  481  AASNVGLP  488
            AASNVGLP
Sbjct  481  AASNVGLP  488


>gi|254366542|ref|ZP_04982586.1| hydrogenase hycQ [Mycobacterium tuberculosis str. Haarlem]
 gi|134152054|gb|EBA44099.1| hydrogenase hycQ [Mycobacterium tuberculosis str. Haarlem]
Length=488

 Score =  920 bits (2377),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 487/488 (99%), Positives = 488/488 (100%), Gaps = 0/488 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG
Sbjct  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL
Sbjct  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIW+AIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVCANNIGVIWIAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG
Sbjct  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST
Sbjct  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL
Sbjct  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI
Sbjct  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480

Query  481  AASNVGLP  488
            AASNVGLP
Sbjct  481  AASNVGLP  488


>gi|31791264|ref|NP_853757.1| hydrogenase HycQ [Mycobacterium bovis AF2122/97]
 gi|121635999|ref|YP_976222.1| putative hydrogenase hycQ [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224988472|ref|YP_002643159.1| putative hydrogenase [Mycobacterium bovis BCG str. Tokyo 172]
 gi|31616849|emb|CAD92951.1| POSSIBLE HYDROGENASE HYCQ [Mycobacterium bovis AF2122/97]
 gi|121491646|emb|CAL70104.1| Possible hydrogenase hycQ [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224771585|dbj|BAH24391.1| putative hydrogenase [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341600015|emb|CCC62683.1| possible hydrogenase hycQ [Mycobacterium bovis BCG str. Moreau 
RDJ]
Length=488

 Score =  918 bits (2372),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 487/488 (99%), Positives = 487/488 (99%), Gaps = 0/488 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG
Sbjct  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA VL
Sbjct  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCATVL  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG
Sbjct  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST
Sbjct  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL
Sbjct  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI
Sbjct  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480

Query  481  AASNVGLP  488
            AASNVGLP
Sbjct  481  AASNVGLP  488


>gi|308373882|ref|ZP_07433990.2| hydrogenase hycQ [Mycobacterium tuberculosis SUMu006]
 gi|308375060|ref|ZP_07667938.1| hydrogenase hycQ [Mycobacterium tuberculosis SUMu007]
 gi|308376301|ref|ZP_07668248.1| hydrogenase hycQ [Mycobacterium tuberculosis SUMu008]
 7 more sequence titles
 Length=485

 Score =  914 bits (2363),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 484/485 (99%), Positives = 485/485 (100%), Gaps = 0/485 (0%)

Query  4    LLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLR  63
            +LLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLR
Sbjct  1    MLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLR  60

Query  64   ADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVC  123
            ADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVC
Sbjct  61   ADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVC  120

Query  124  ANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAAR  183
            ANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAAR
Sbjct  121  ANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAAR  180

Query  184  DSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPA  243
            DSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPA
Sbjct  181  DSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPA  240

Query  244  PVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVK  303
            PVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVK
Sbjct  241  PVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVK  300

Query  304  RMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIA  363
            RMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIA
Sbjct  301  RMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIA  360

Query  364  DITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAI  423
            DITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAI
Sbjct  361  DITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAI  420

Query  424  GFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGIAAS  483
            GFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGIAAS
Sbjct  421  GFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGIAAS  480

Query  484  NVGLP  488
            NVGLP
Sbjct  481  NVGLP  485


>gi|289748554|ref|ZP_06507932.1| LOW QUALITY PROTEIN: hydrogenase hycQ [Mycobacterium tuberculosis 
T92]
 gi|289689141|gb|EFD56570.1| LOW QUALITY PROTEIN: hydrogenase hycQ [Mycobacterium tuberculosis 
T92]
Length=489

 Score =  788 bits (2035),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/416 (100%), Positives = 416/416 (100%), Gaps = 0/416 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG
Sbjct  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL
Sbjct  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG
Sbjct  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST
Sbjct  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGA  416
            AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGA
Sbjct  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGA  416


>gi|340625121|ref|YP_004743573.1| putative hydrogenase HYCQ [Mycobacterium canettii CIPT 140010059]
 gi|340003311|emb|CCC42428.1| putative hydrogenase HYCQ [Mycobacterium canettii CIPT 140010059]
Length=489

 Score =  764 bits (1972),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/488 (93%), Positives = 465/488 (96%), Gaps = 0/488 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAPLAASIA ++ GWR TTATLT LSA TVLACAV M F  GSGAQFGLGG
Sbjct  1    MTGLLLAAILAPLAASIAGMVAGWRHTTATLTVLSAATVLACAVVMAFRTGSGAQFGLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLRADALTV+MLVVIGIVGTLATAASIGYID ELAHGHID R ARLYGVLTPAFLCAMVL
Sbjct  61   LLRADALTVIMLVVIGIVGTLATAASIGYIDAELAHGHIDERGARLYGVLTPAFLCAMVL  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIA+AFLGTVLLYF
Sbjct  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAIAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AARD+GAA A ALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AARDAGAADASALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLLAVA SVLIRLRPI+DA +GP YLRNGL+VVGLATLLVAVLMLTVTG
Sbjct  241  APAPVSALMSGVLLAVALSVLIRLRPIIDAATGPTYLRNGLVVVGLATLLVAVLMLTVTG  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            DVKRMLAYSSME+MGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHD T
Sbjct  301  DVKRMLAYSSMENMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDCT  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            A+ADITGV+RRSRLIGVSFA G+IVLLGLPPFAMFASELAIARSLA+ RLAWVLGAALLL
Sbjct  361  AVADITGVLRRSRLIGVSFATGVIVLLGLPPFAMFASELAIARSLAHARLAWVLGAALLL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            IAIGF ALARNSGR+LLGTPAAGAPAITVPATAAAAL+ GIVVSAALGITAGPL DLLGI
Sbjct  421  IAIGFAALARNSGRILLGTPAAGAPAITVPATAAAALIAGIVVSAALGITAGPLTDLLGI  480

Query  481  AASNVGLP  488
            AASNVGLP
Sbjct  481  AASNVGLP  488


>gi|118617495|ref|YP_905827.1| hydrogenase HycQ [Mycobacterium ulcerans Agy99]
 gi|118569605|gb|ABL04356.1| hydrogenase HycQ [Mycobacterium ulcerans Agy99]
Length=488

 Score =  645 bits (1664),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 351/486 (73%), Positives = 392/486 (81%), Gaps = 0/486 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MT L+L  I+APL A+  +L  GWRR TA LT LSA  VL   +A+G          LGG
Sbjct  1    MTALILVPIVAPLVAAAFALAGGWRRATAVLTVLSAVAVLGSGIALGLQATPQPHLVLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLR DAL+V+ML+VIG VGTLAT ASIGYID EL HGH D R ARLYG L PAFL AM +
Sbjct  61   LLRVDALSVIMLIVIGAVGTLATWASIGYIDAELEHGHTDRRDARLYGALMPAFLAAMAI  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AV ANNIG+IWVA+EATTV+TAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVSANNIGLIWVAVEATTVVTAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AA+ +GA  A ALNLD+L   AA L+P V RLAGGLLLIGYGAK GL PFH WLADAHSQ
Sbjct  181  AAQHAGADGANALNLDVLTACAAHLNPAVTRLAGGLLLIGYGAKVGLAPFHGWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLL+VAFSVLIRLRP++DA  GP YLR GLL VGL T+L+A  +LTV  
Sbjct  241  APAPVSALMSGVLLSVAFSVLIRLRPVIDAAVGPGYLRAGLLTVGLTTVLIAAFLLTVVT  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KRMLAYSSME+MGLIAIAAAAGT LAIAALLLHVLAHGIGKTVLFLAGGQLQ+AHDS 
Sbjct  301  DLKRMLAYSSMENMGLIAIAAAAGTKLAIAALLLHVLAHGIGKTVLFLAGGQLQSAHDSA  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            +IADIT V+ RSR++GVSFAVG++VLLGLPPFAMF+SE++IARSLAN  LAWVLG  LLL
Sbjct  361  SIADITAVLSRSRVVGVSFAVGVVVLLGLPPFAMFSSEVSIARSLANSGLAWVLGVTLLL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            + + F AL  NS RMLLG  + GAP I VPAT AAAL+ G+V   ALG+TAGPL  L   
Sbjct  421  MVVAFAALVANSRRMLLGAASEGAPRIAVPATVAAALVTGVVACIALGVTAGPLGGLFDA  480

Query  481  AASNVG  486
            AA   G
Sbjct  481  AAGQFG  486


>gi|183981672|ref|YP_001849963.1| hydrogenase HycQ [Mycobacterium marinum M]
 gi|183174998|gb|ACC40108.1| hydrogenase HycQ [Mycobacterium marinum M]
Length=488

 Score =  644 bits (1661),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 351/486 (73%), Positives = 392/486 (81%), Gaps = 0/486 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MT L+L  I+APL A+  +L  GWRR TA LT LSA  VL   +A+G          LGG
Sbjct  1    MTALILVPIVAPLVAAAFALAGGWRRATAVLTVLSAVAVLGSGIALGLQATPQPHLVLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLR DAL+V+ML+VIG VGTLAT ASIGYID EL HGH D R ARLYG L PAFL AM +
Sbjct  61   LLRVDALSVIMLIVIGAVGTLATWASIGYIDAELEHGHTDRRDARLYGALMPAFLAAMAI  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AV ANNIG+IWVA+EATTV+TAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVSANNIGLIWVAVEATTVVTAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AA+ +GA  A ALNLD+L   AA L+P V RLAGGLLLIGYGAK GL PFH WLADAHSQ
Sbjct  181  AAQHAGADGANALNLDVLTACAAHLNPAVTRLAGGLLLIGYGAKVGLAPFHGWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLL+VAFSVLIRLRP++DA  GP YLR GLL VGL T+L+A  +LTV  
Sbjct  241  APAPVSALMSGVLLSVAFSVLIRLRPVIDAAVGPGYLRAGLLTVGLTTVLIAAFLLTVVT  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KRMLAYSSME+MGLIAIAAAAGT LAIAALLLHVLAHGIGKTVLFLAGGQLQ+AHDS 
Sbjct  301  DLKRMLAYSSMENMGLIAIAAAAGTKLAIAALLLHVLAHGIGKTVLFLAGGQLQSAHDSA  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            +IADIT V+ RSR++GVSFAVG++VLLGLPPFAMFASE++IARSLA+  LAWVLG  LLL
Sbjct  361  SIADITAVLSRSRVVGVSFAVGVVVLLGLPPFAMFASEVSIARSLADSGLAWVLGVTLLL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            + + F AL  NS RMLLG  + GAP I VPAT AAAL+ G+V   ALG+TAGPL  L   
Sbjct  421  MVVAFAALVANSRRMLLGAASEGAPRIAVPATVAAALVTGVVACIALGVTAGPLGGLFDA  480

Query  481  AASNVG  486
            AA   G
Sbjct  481  AAGQFG  486


>gi|240169558|ref|ZP_04748217.1| hydrogenase HycQ [Mycobacterium kansasii ATCC 12478]
Length=488

 Score =  636 bits (1641),  Expect = 2e-180, Method: Compositional matrix adjust.
 Identities = 354/486 (73%), Positives = 401/486 (83%), Gaps = 0/486 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MT L+L  ILAPL A++ ++  GWRR TATLT LSA  VLA  VA+G    +  +  L G
Sbjct  1    MTVLMLVPILAPLIAAVVAMAGGWRRWTATLTVLSAVAVLASGVALGVQTAARPRVLLAG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            +LR DAL+V ML+VIG+VG+LAT ASIGY+D+EL   H D R AR YG LTPAFL AM +
Sbjct  61   MLRVDALSVTMLIVIGVVGSLATWASIGYLDSELEDDHTDLRDARRYGALTPAFLSAMAV  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIWVA+EATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGT +LYF
Sbjct  121  AVCANNIGVIWVAVEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTAMLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AAR +GA  A AL+LD+L  HAA LDP V RLAGGLLLIGYGAK GL PFH WLADAHSQ
Sbjct  181  AARHAGAVGATALDLDVLTAHAAHLDPAVTRLAGGLLLIGYGAKVGLVPFHGWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLL+VAFSVLIRLRPI+DA  GP +LR+GLL  GLAT+L+A L+LTVT 
Sbjct  241  APAPVSALMSGVLLSVAFSVLIRLRPIIDAAVGPGFLRSGLLTAGLATVLIAALLLTVTT  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KRMLAYSSME+MGLIAIAAAAGT LAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST
Sbjct  301  DLKRMLAYSSMENMGLIAIAAAAGTKLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            AI +IT V+ RSRL+G SFAVG+I LLGLPPFAMFASE+AIARSLA+  L+WVLG AL+L
Sbjct  361  AIGEITAVLSRSRLVGWSFAVGVIALLGLPPFAMFASEVAIARSLASAGLSWVLGVALVL  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGI  480
            + + F A+A N+ R+LLG P+AGAP I VPAT AAA+  G++ S ALG TAGPLA L   
Sbjct  421  MVVAFAAVAGNAQRILLGVPSAGAPRIAVPATVAAAVTTGVIASVALGATAGPLAGLFNA  480

Query  481  AASNVG  486
            AA   G
Sbjct  481  AAGQFG  486


>gi|342862429|ref|ZP_08719069.1| putative hydrogenase HycQ [Mycobacterium colombiense CECT 3035]
 gi|342130100|gb|EGT83434.1| putative hydrogenase HycQ [Mycobacterium colombiense CECT 3035]
Length=492

 Score =  630 bits (1626),  Expect = 1e-178, Method: Compositional matrix adjust.
 Identities = 382/489 (79%), Positives = 416/489 (86%), Gaps = 3/489 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAP+AAS+A+LI GWRR TA+LT LSA TV AC VA+G   GSGA+F LGG
Sbjct  1    MTGLLLAAILAPVAASLATLIGGWRRATASLTVLSAATVFACGVALGCGAGSGARFALGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLR DAL+V ML+VIG V TLAT AS+GYI TELA GH D R AR YGVLTPAFL AMV+
Sbjct  61   LLRVDALSVTMLIVIGTVATLATWASVGYIGTELARGHTDARGARTYGVLTPAFLAAMVV  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AV ANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIA+AFLGTVLLY+
Sbjct  121  AVSANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAIAFLGTVLLYY  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AA  +GA AA ALNLD L  HAA LD G ARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AAEHAGAPAAAALNLDALTAHAAQLDSGTARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLL+VA SVLIR+RPI+DA +G A++R+GLLV GLATL++A LMLTVT 
Sbjct  241  APAPVSALMSGVLLSVAVSVLIRIRPIIDAATGTAFMRSGLLVTGLATLIIAALMLTVTS  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KRMLAYSSME+MGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST
Sbjct  301  DIKRMLAYSSMENMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            AIADIT V+RRSR++GVS   G+IVLLGLPPFAMFASEL+I R+LAN RL WVL A LL 
Sbjct  361  AIADITAVLRRSRMLGVSIVAGVIVLLGLPPFAMFASELSIVRALANARLTWVLAAGLLA  420

Query  421  IAIGFTALARNSGRMLLGTPAAG---APAITVPATAAAALMVGIVVSAALGITAGPLADL  477
            IAI F ALARNSGR+LLG        AP I VP T AAAL +G+  S ALG+TAGPLA L
Sbjct  421  IAIAFAALARNSGRILLGGATGASEVAPEIVVPKTIAAALTLGVAASIALGVTAGPLAGL  480

Query  478  LGIAASNVG  486
               AA  VG
Sbjct  481  FTAAAGIVG  489


>gi|296166647|ref|ZP_06849073.1| hydrogenase-4, F subunit [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295897982|gb|EFG77562.1| hydrogenase-4, F subunit [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=488

 Score =  627 bits (1618),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 359/478 (76%), Positives = 407/478 (86%), Gaps = 1/478 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MT  LLAAILAP+ AS+A L+ GWRR+TATL ALSA TVLAC  A+ F +GSG +  LGG
Sbjct  1    MTAPLLAAILAPVGASVAVLVAGWRRSTATLIALSALTVLACGAALAFRVGSGTRLALGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLR DAL+V ML+VIG V  LAT AS+GY++ EL  GH D   AR+YG LT  FL AMV+
Sbjct  61   LLRLDALSVTMLIVIGTVAALATWASVGYLEIELERGHTDPAGARVYGALTAGFLAAMVV  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIW+AIEATTVITAFLVGHRRTR ALEATWKYVVICSVGIAVAFLGTVLLY+
Sbjct  121  AVCANNIGVIWIAIEATTVITAFLVGHRRTRGALEATWKYVVICSVGIAVAFLGTVLLYY  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AA  +GA AA ALNLD+L  HA GLDPG+ARLAGGLLL+GYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AAEHAGAPAAAALNLDVLTAHAGGLDPGIARLAGGLLLVGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            APAPVSALMSGVLL+VAFSV++RL PI+   +GPA++R+GLLV+GLATL+VA LMLTV  
Sbjct  241  APAPVSALMSGVLLSVAFSVVLRLEPIIGTATGPAFMRSGLLVIGLATLVVAALMLTVAA  300

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KRMLAYSSME+MGLIAIAAAAGT+LAIAALLLHVLAHGIGKTVLFL+ GQLQA H+ST
Sbjct  301  DIKRMLAYSSMENMGLIAIAAAAGTSLAIAALLLHVLAHGIGKTVLFLSSGQLQATHNST  360

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
            AIADI  V+RRSRL+GVS AVG++VLLGLPPFAMFASELAI RSLA+ RL WVL AA+L 
Sbjct  361  AIADINAVLRRSRLLGVSLAVGVVVLLGLPPFAMFASELAIVRSLADARLTWVLAAAMLF  420

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLL  478
            +A+ F ALARN+GR+LLG  A  AP I VP T AAAL+VG+  S ALG+TAGPL DL 
Sbjct  421  VAVAFAALARNAGRILLGG-AGAAPEIVVPRTVAAALLVGVGASIALGVTAGPLTDLF  477


>gi|118462524|ref|YP_884228.1| hydrogenase-4, F subunit, putative [Mycobacterium avium 104]
 gi|118163811|gb|ABK64708.1| hydrogenase-4, F subunit, putative [Mycobacterium avium 104]
Length=489

 Score =  592 bits (1526),  Expect = 5e-167, Method: Compositional matrix adjust.
 Identities = 364/464 (79%), Positives = 394/464 (85%), Gaps = 0/464 (0%)

Query  23   GWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVIGIVGTLA  82
            GWRR T+T+T LSA TVL C  A+ F +GS   F LGGLLR DAL V ML+VIGIVGTLA
Sbjct  23   GWRRLTSTVTVLSAATVLGCGAALSFTVGSQQYFVLGGLLRVDALCVTMLIVIGIVGTLA  82

Query  83   TAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAIEATTVITA  142
            T ASIGYID E A GH D   ARLYG LTPAFL AMV+AVCANNIGVIWVAIEATTVITA
Sbjct  83   TWASIGYIDAECADGHTDAGGARLYGALTPAFLAAMVVAVCANNIGVIWVAIEATTVITA  142

Query  143  FLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHA  202
            FLVGHRRTRTALEATWKYV+ICSVGIA+AFLGTVLLYFAAR +GA+AA ALNLD+L  HA
Sbjct  143  FLVGHRRTRTALEATWKYVIICSVGIAIAFLGTVLLYFAARHAGASAALALNLDVLGAHA  202

Query  203  AGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLI  262
              LDP V+RLAGGLLLIGYGAKAGL PFHTWLADAHSQAPAPVSALMSGVLL+VA SVLI
Sbjct  203  HTLDPAVSRLAGGLLLIGYGAKAGLAPFHTWLADAHSQAPAPVSALMSGVLLSVAMSVLI  262

Query  263  RLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAA  322
            R+ PI+ A +GP +LR GLL VGL TL VA LMLTVTGDVKRMLAYSSME+MGLIAIAAA
Sbjct  263  RITPIVGAAAGPTFLRAGLLTVGLVTLFVAALMLTVTGDVKRMLAYSSMENMGLIAIAAA  322

Query  323  AGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVG  382
            AGTTLAIAALLLHVLAHG+GKTVLFLAGGQLQAAH STAIADITGV++RS LIG SFAVG
Sbjct  323  AGTTLAIAALLLHVLAHGVGKTVLFLAGGQLQAAHGSTAIADITGVVQRSHLIGGSFAVG  382

Query  383  LIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNSGRMLLGTPAA  442
            LIVLLGLPPFAMFASELA+A +LA+ RLAWVLGAA+LLIAI F AL RN+ RMLLG  AA
Sbjct  383  LIVLLGLPPFAMFASELALAHALADARLAWVLGAAMLLIAIAFAALVRNASRMLLGPAAA  442

Query  443  GAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGIAASNVG  486
             AP IT P T  AAL+VG+  S  LG+TAGPL DL   AA  +G
Sbjct  443  AAPPITAPTTVTAALLVGVAASIVLGVTAGPLTDLFSTAAGQLG  486


>gi|333991246|ref|YP_004523860.1| hydrogenase HycQ [Mycobacterium sp. JDM601]
 gi|333487214|gb|AEF36606.1| hydrogenase HycQ [Mycobacterium sp. JDM601]
Length=487

 Score =  543 bits (1399),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 334/472 (71%), Positives = 390/472 (83%), Gaps = 1/472 (0%)

Query  15   ASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVV  74
            AS+ S+  GWRR +A  T  SA T+L C VA+GF +   A   L GLLRADAL+  ML+V
Sbjct  15   ASLLSVAVGWRRLSAVATLGSALTILGCGVALGFRVDDRAHLALNGLLRADALSATMLIV  74

Query  75   IGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAI  134
            IG+V +LAT ASIGY+D ELA G  D R AR+YGVLTPAFL AMVLAV ANNIGV+WVA+
Sbjct  75   IGVVASLATWASIGYVDAELARGVTDRRGARIYGVLTPAFLAAMVLAVSANNIGVVWVAV  134

Query  135  EATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALN  194
            EATTV+TAFLVGH R+R ALEATWKYV++CSVGI VAFLGTVLL+FAAR +GA    AL+
Sbjct  135  EATTVVTAFLVGHHRSRAALEATWKYVMVCSVGITVAFLGTVLLHFAARHAGAGD-DALH  193

Query  195  LDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLL  254
            LD+LA HAA LDP V RLAG LLLIGYGAK GL PFHTWLADAHSQAPAPVSALMSGVLL
Sbjct  194  LDVLAAHAAALDPAVTRLAGALLLIGYGAKMGLAPFHTWLADAHSQAPAPVSALMSGVLL  253

Query  255  AVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHM  314
            +VAFSVLIRL+PI+DA +GPA+LR  LL  GLATLL+A L+LTVT D+KR+LAYSSME M
Sbjct  254  SVAFSVLIRLKPIIDAATGPAFLRAALLATGLATLLIAALLLTVTTDLKRLLAYSSMETM  313

Query  315  GLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRL  374
            GL+A+AAAAGT LA+AALLLHVLAHG+GKTVLFLAGGQLQAAH +TAI++ITGV+ RSRL
Sbjct  314  GLMAVAAAAGTRLAVAALLLHVLAHGVGKTVLFLAGGQLQAAHGTTAISEITGVLGRSRL  373

Query  375  IGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNSGR  434
            +G +FAVG++VLLGLPPFAMFASELAIA +LA+ RLAW LG AL+ + + F AL   SGR
Sbjct  374  VGGAFAVGMVVLLGLPPFAMFASELAIATALADARLAWALGLALVALLVAFAALMAKSGR  433

Query  435  MLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGIAASNVG  486
            +LLGTP+A  P I VPAT AAAL+ G++VS ALG+TAGPL  L   AA+ +G
Sbjct  434  ILLGTPSADGPTILVPATVAAALVTGVLVSLALGVTAGPLTGLFTAAATQLG  485


>gi|298527478|ref|ZP_07014887.1| hydrogenase [Mycobacterium tuberculosis 94_M4241A]
 gi|298497272|gb|EFI32566.1| hydrogenase [Mycobacterium tuberculosis 94_M4241A]
Length=293

 Score =  524 bits (1349),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 274/280 (98%), Positives = 274/280 (98%), Gaps = 0/280 (0%)

Query  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60
            MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG
Sbjct  1    MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGG  60

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
            LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL
Sbjct  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF
Sbjct  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
            AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ
Sbjct  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNG  280
            APAPVSALMSGVLLAVAFSVLIRLRPILDAVSG      G
Sbjct  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGSPTCATG  280


>gi|336178231|ref|YP_004583606.1| NADH dehydrogenase (quinone) [Frankia symbiont of Datisca glomerata]
 gi|334859211|gb|AEH09685.1| NADH dehydrogenase (quinone) [Frankia symbiont of Datisca glomerata]
Length=527

 Score =  373 bits (958),  Expect = 4e-101, Method: Compositional matrix adjust.
 Identities = 242/492 (50%), Positives = 319/492 (65%), Gaps = 15/492 (3%)

Query  4    LLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWM-GSGAQFGLGGLL  62
            LL A +   LA +    + GWR  TA    +S  T+L CA+ +   + G G   G GGL 
Sbjct  34   LLTAPVAVALATAAGYAVLGWRPATAWAGLVSPATILGCAIVLAVRVPGHGPVTGYGGLA  93

Query  63   RADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAV  122
            RADAL+  +L+VIG V  LA AAS  Y+  E A GH D R AR YG+L  AFL AM +AV
Sbjct  94   RADALSAWILLVIGAVAVLACAASPAYLAAENAAGHTDARGARRYGILVHAFLAAMAVAV  153

Query  123  CANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAA  182
               N+GV+WVAIEATT++TAFLVGHRRTR ++EA WKYVVICS GIA+AFLGT+L+Y+AA
Sbjct  154  LVANLGVLWVAIEATTIVTAFLVGHRRTRASVEAAWKYVVICSAGIALAFLGTILIYYAA  213

Query  183  RDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAP  242
            R +G + A AL+  +L   A  LDP V R+   L+++G+GAKAGL P H WL DAHSQAP
Sbjct  214  RQAGISEASALDWPVLVARAHELDPAVTRMGIALVILGFGAKAGLVPLHAWLPDAHSQAP  273

Query  243  APVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG--  300
            APVSALMSGVLLAV+F+ ++R + I D   GP + R   L+VG A L +A+    + G  
Sbjct  274  APVSALMSGVLLAVSFTAILRYKVIADVALGPGFART--LLVGAAVLTLALAAALLLGQR  331

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D KRMLAYSSMEHM LIA+ AAAG+ LA +A+LLH+  HG+ K+V F + G +     +T
Sbjct  332  DYKRMLAYSSMEHMSLIALGAAAGSRLATSAVLLHIAGHGLAKSVAFCSSGHILHLRHTT  391

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARS--LANERLAWVLGAAL  418
             I  + G++ ++ ++  +F + ++ LLG PPF++FASELAIAR+       L W   AAL
Sbjct  392  RIGRVRGLLGQAPVLAAAFGLAVLALLGFPPFSLFASELAIARAGFTGPAGLGWATAAAL  451

Query  419  LLIAIGFTALARNSGRMLLGTPAAGAPAIT---VPATAAAA----LMVGIVVSAALGITA  471
            +L+   F A+   +  MLLG PA G    T   VP    AA    L VG++  AALG++ 
Sbjct  452  VLVLAAFAAMTVRTAHMLLG-PAPGRDGGTTAAVPVRFGAAVWVPLAVGLLACAALGVSD  510

Query  472  GPLADLLGIAAS  483
             PL+ LL  AA+
Sbjct  511  VPLSSLLSTAAA  522


>gi|317126122|ref|YP_004100234.1| NADH/Ubiquinone/plastoquinone (complex I) [Intrasporangium calvum 
DSM 43043]
 gi|315590210|gb|ADU49507.1| NADH/Ubiquinone/plastoquinone (complex I) [Intrasporangium calvum 
DSM 43043]
Length=510

 Score =  372 bits (954),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 223/439 (51%), Positives = 293/439 (67%), Gaps = 5/439 (1%)

Query  12   PLAASIASLITGWRRTTATLTALSATTV-----LACAVAMGFWMGSGAQFGLGGLLRADA  66
            PLAA +   +T W   T  L A+ A+ V     L   VA+      G    +G  LR DA
Sbjct  30   PLAAPLLVSMTAWFIRTDRLLAVRASIVAAAVILGSGVAVAVVNVRGEVPAVGSTLRVDA  89

Query  67   LTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANN  126
            L+ VML+VIG VG +AT AS+ Y+  E+  GH   R  R Y VL PAFL AMVLAV ANN
Sbjct  90   LSAVMLIVIGAVGLIATTASVDYLQGEINGGHTTDRRVRAYSVLLPAFLTAMVLAVVANN  149

Query  127  IGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSG  186
            +G++W AIEATT++TAFLVGH R+R ++EATWKYV+ICSVGIA+A+LGTVL+++AAR +G
Sbjct  150  LGLLWAAIEATTIVTAFLVGHHRSRGSVEATWKYVIICSVGIALAYLGTVLVHYAARHAG  209

Query  187  AAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVS  246
             A + AL+   L+  AA LDP V R+A  LL++G+GAKAG+ P H+WL DAHSQAPAPVS
Sbjct  210  LAESAALDWTALSAGAARLDPDVMRVAFALLVLGFGAKAGMAPLHSWLPDAHSQAPAPVS  269

Query  247  ALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRML  306
            ALMSGVLL VA   L+R R I     G   +R  LLVV L +L +A  ++    D KR+L
Sbjct  270  ALMSGVLLPVAVYALLRYRVIAAPSLGEHQVRLLLLVVALGSLALAASLIIAQRDYKRLL  329

Query  307  AYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADIT  366
            AYSS+EHM L+ I  A GT LA+AALLLH++ HG+GK VLF   G++ A   ST+I  + 
Sbjct  330  AYSSIEHMSLVVIGVAIGTPLAVAALLLHIVGHGLGKAVLFCGAGRILATEGSTSIRSVR  389

Query  367  GVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFT  426
            G++ R   +   FA G+  LLGLPPF++FASE+ +AR+  +  L WV+ AA+ L+A+ F 
Sbjct  390  GLLVRRPALAAVFAAGIAALLGLPPFSLFASEVGLARAGTSAGLGWVIAAAMALVAVIFV  449

Query  427  ALARNSGRMLLGTPAAGAP  445
            A+  +   M+LG P  G P
Sbjct  450  AITVHVAPMVLGRPTPGQP  468


>gi|119718685|ref|YP_925650.1| NADH dehydrogenase (quinone) [Nocardioides sp. JS614]
 gi|119539346|gb|ABL83963.1| NADH dehydrogenase (quinone) [Nocardioides sp. JS614]
Length=428

 Score =  313 bits (802),  Expect = 5e-83, Method: Compositional matrix adjust.
 Identities = 207/429 (49%), Positives = 274/429 (64%), Gaps = 13/429 (3%)

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
            L GLLR DAL+  ML VIG VG     A+ G +D      H+       Y VL   FL A
Sbjct  11   LDGLLRVDALSAFMLTVIGSVGL---TAAWGALDPLRPRDHV-------YSVLALLFLGA  60

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M LAV A+N+GV+W+A+EATT+ TAF+VGH RTR A+EA WKYVV+ SVG+A+AFLG VL
Sbjct  61   MSLAVLADNLGVLWIAVEATTIATAFMVGHHRTRRAIEAAWKYVVLGSVGVAIAFLGIVL  120

Query  178  LYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADA  237
            LY A R +G      L+  +LA     LDP V R+A  L ++G+  KAGL P H+WL DA
Sbjct  121  LYAATRSAGEPT---LSWSVLATTHPDLDPSVVRVAAALAILGFATKAGLAPMHSWLPDA  177

Query  238  HSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLT  297
            HSQAPAPVS LMSGVLLAVAF  ++R++ I   V G   +R  L+  GL +L +A L++ 
Sbjct  178  HSQAPAPVSGLMSGVLLAVAFYAILRVQAIATPVIGTGLMRGLLVTAGLLSLTLAALLVI  237

Query  298  VTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAH  357
               D+KRMLAYSS+EHMGL+A+AAAAG  LAIA  LLHVL HG+ K+  F+A G++ AA 
Sbjct  238  RQRDLKRMLAYSSIEHMGLLALAAAAGGRLAIAGALLHVLGHGLAKSSTFVASGRILAAE  297

Query  358  DSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAA  417
             +T +ADI G++ R   + V F VG++ LLGLPPF++F SE+AI      + L W +  A
Sbjct  298  GTTTMADIHGLVARRPGVAVPFLVGVVALLGLPPFSLFFSEVAIVVGGVQQGLGWAMAVA  357

Query  418  LLLIAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADL  477
            +L++ + F A++R+   ML G  AA       P      L++ +  +  +G  AGP A L
Sbjct  358  VLMLLVMFVAMSRHVVAMLFGGAAAATDPDRAPYGPRLPLVLALAATGVVGFVAGPFATL  417

Query  478  LGIAASNVG  486
            L  AAS +G
Sbjct  418  LDRAASVLG  426


>gi|258653158|ref|YP_003202314.1| NADH/Ubiquinone/plastoquinone (complex I) [Nakamurella multipartita 
DSM 44233]
 gi|258556383|gb|ACV79325.1| NADH/Ubiquinone/plastoquinone (complex I) [Nakamurella multipartita 
DSM 44233]
Length=537

 Score =  311 bits (796),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 202/396 (52%), Positives = 268/396 (68%), Gaps = 11/396 (2%)

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
            LGGLL ADAL+  MLVVIG V  +A  A+ G++  ELA G ID  +   +  L   FL A
Sbjct  73   LGGLLAADALSAFMLVVIGAVALIAALATPGHLRVELAAGRIDATTRTRHLALVQLFLAA  132

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M LAV A  +G++WVA+E TTV+TAFLVG  R R A EA WKYV+ICS GIA+A LGT L
Sbjct  133  MALAVLAAGLGLLWVAVELTTVVTAFLVGQGRGRRAAEAAWKYVIICSTGIALALLGTFL  192

Query  178  LYFAARDSGAAAAGALNLDILAEHAAG--LDPGVARLAGGLLLIGYGAKAGLFPFHTWLA  235
            L  AA  +GA      +LD L+  AAG  LDPGV R+A  LL++G+G KAGL P H WL 
Sbjct  193  LNAAAERAGA------SLDWLSLTAAGPDLDPGVTRIAVVLLVLGFGTKAGLAPMHAWLP  246

Query  236  DAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLM  295
            DAHSQAPAPVSALMSGVL++VAF  ++R++ + D   GP + R  L+V+ LA++ +A  +
Sbjct  247  DAHSQAPAPVSALMSGVLISVAFYAVLRVKVVADLALGPDFTRALLIVLALASIALAASL  306

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            L    D KRMLAYSS+E+M L+A+ AA G+ LAIAA+LLH+L HG+ K+ LF+A G++  
Sbjct  307  LIAQRDYKRMLAYSSIENMALLALGAAIGSPLAIAAVLLHILGHGLVKSGLFVAAGRILQ  366

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
               ++ I  + G++ R  ++G  F +G++ ++  PPF++FASEL IAR+     L WV  
Sbjct  367  LTGTSRIDHVRGLVAREPVLGWCFGLGILAIVAFPPFSLFASELGIARAGFAAGLGWVTA  426

Query  416  AALLLIAIGFTALARNSGRMLLGTPAA---GAPAIT  448
            AALLL+ +   AL  ++ RMLLG PAA   GAPA T
Sbjct  427  AALLLVLVCAAALIGHTSRMLLGAPAATANGAPATT  462


>gi|269128895|ref|YP_003302265.1| NADH/Ubiquinone/plastoquinone (complex I) [Thermomonospora curvata 
DSM 43183]
 gi|268313853|gb|ACZ00228.1| NADH/Ubiquinone/plastoquinone (complex I) [Thermomonospora curvata 
DSM 43183]
Length=572

 Score =  308 bits (788),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 234/433 (55%), Positives = 301/433 (70%), Gaps = 13/433 (3%)

Query  13   LAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVML  72
            LAA++ +L  GWR     L ALS+  VLAC +A+       +  GL    RADAL+  ML
Sbjct  13   LAAAVYAL-AGWRGPVRWLGALSSAGVLACGIALSLQQAPPSAPGL----RADALSSFML  67

Query  73   VVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWV  132
            +VIG V TLA  A   Y+  E        R+AR YGVLT  F+ AM LAV A N+GV+WV
Sbjct  68   IVIGAVATLAMLAGPSYLAAEDDA-----RAARRYGVLTQGFIAAMALAVLAANLGVLWV  122

Query  133  AIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGA  192
            A+EATT++TAFLVGHRRTR A+EA WKYVV+CS GIA+A LG VLL+FAA  +G  +   
Sbjct  123  AVEATTIVTAFLVGHRRTRAAVEAAWKYVVVCSAGIALALLGVVLLHFAAAQAGVES---  179

Query  193  LNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGV  252
            L LD+LA HAA LDPGVAR+A  LLL+G+G KAGL P H WL DAHSQAPAPVSALMSGV
Sbjct  180  LELDVLAAHAADLDPGVARIAVALLLLGFGTKAGLAPMHAWLPDAHSQAPAPVSALMSGV  239

Query  253  LLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSME  312
            LL+VAF  ++R++ I D   GPA+ RN LLV+ L +LLVA L+L    D KRMLAYSS+E
Sbjct  240  LLSVAFYAMLRVKVIADPALGPAFTRNLLLVLALLSLLVAALLLIAQRDYKRMLAYSSIE  299

Query  313  HMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRS  372
            HMGL+A+ AAAG  LA+ A+LLHVL HG+GK+VLF+  G +  A  S+ +A + G++ RS
Sbjct  300  HMGLLALGAAAGGRLALTAVLLHVLGHGLGKSVLFIGSGTILHATGSSRVAAVRGLLARS  359

Query  373  RLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNS  432
             L+G +F + L+ LLGLPPF++FASEL I R+   + + W +  AL+L+ +   A+ R  
Sbjct  360  PLLGGAFGLALLALLGLPPFSLFASELGIFRAGFQDGIGWAVAVALVLLLVIVAAVGRIG  419

Query  433  GRMLLGTPAAGAP  445
             RM+LG+P +  P
Sbjct  420  SRMILGSPLSAQP  432


>gi|325578548|ref|ZP_08148648.1| hydrogenase-4 component F [Haemophilus parainfluenzae ATCC 33392]
 gi|325159784|gb|EGC71914.1| hydrogenase-4 component F [Haemophilus parainfluenzae ATCC 33392]
Length=512

 Score =  291 bits (746),  Expect = 1e-76, Method: Compositional matrix adjust.
 Identities = 183/480 (39%), Positives = 275/480 (58%), Gaps = 7/480 (1%)

Query  5    LLAAILAPLAASIASLITGWRRTTATLTALSAT-TVLACAVAMGFWMG---SGAQFGLGG  60
            ++A ++APLA S+AS   G  +     TAL  T  +L  A A+    G    G    L  
Sbjct  6    IIALLIAPLAISLASFACGVTKARTICTALHVTGLILMLAFALQIINGVLTQGEISALNN  65

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRS-ARLYGVLTPAFLCAMV  119
             +  D+L+ + L +I IVGTLA   SIGYI TE   GH+D ++    YG L   F   M+
Sbjct  66   WVYIDSLSAIFLGLIAIVGTLAGIYSIGYISTEYREGHLDLKTYCNYYGFLH-LFFFTMI  124

Query  120  LAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLY  179
            ++V  NN+ ++W AIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L +
Sbjct  125  ISVITNNVILMWAAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTILTF  184

Query  180  FAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHS  239
                +  A  + A+    + + AAGL+P +  LA   +L+G+G K GLFP HTWL+DAHS
Sbjct  185  SNGTNLLADPSQAIFWTEINQQAAGLNPMLMYLAFAFILVGFGTKCGLFPMHTWLSDAHS  244

Query  240  QAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVT  299
            +AP+PVSA++S VLL  A SV++R   ++    G  Y +  LLV GL ++LVA L + V 
Sbjct  245  EAPSPVSAILSAVLLNCAMSVVLRYYILVSKAVGSTYPQTLLLVFGLLSVLVAALFIIVQ  304

Query  300  GDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDS  359
             D+KR+LAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   + +
Sbjct  305  FDIKRLLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKYKT  364

Query  360  TAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALL  419
              +  + G+ R + +  V FA G + L G+PPF +F SE +IA +       W++   L+
Sbjct  365  RDMNQVRGLWRVAPMTAVLFAGGALALGGIPPFNVFVSEFSIAVAGIYAGKTWLMVFCLI  424

Query  420  LIAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGI-TAGPLADLL  478
            L+ I    L+    + +LG          V   +  A+ + ++    +GI  A P+  LL
Sbjct  425  LLTIVLAGLSLMVLKTVLGKQPDNVEVGDVNKVSLVAMAILLLFMFIMGIHIAEPILQLL  484


>gi|258593563|emb|CBE69904.1| Hydrogenase-4 component F [NC10 bacterium 'Dutch sediment']
Length=485

 Score =  285 bits (728),  Expect = 2e-74, Method: Compositional matrix adjust.
 Identities = 169/385 (44%), Positives = 237/385 (62%), Gaps = 8/385 (2%)

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
            +GGLLRAD L+ +M+VVI +VG +A    IGYI  E    H+     R +  L   F+  
Sbjct  56   VGGLLRADGLSALMVVVITLVGAIAALYGIGYIRAEYDDTHLT--RVRSFFALFHVFIFT  113

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M+LAV  +N+G++WVAIE TT+ TAFLV    T  +LEA +KY+++ SVGIA+AF+GT L
Sbjct  114  MLLAVTTDNLGIMWVAIEGTTLATAFLVNLHNTPKSLEAAYKYLILSSVGIALAFIGTAL  173

Query  178  LYFAARDSGAAAAG--ALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLA  235
            +Y+A    GA+ AG  A+N   L   A+ L+P V RLA   +LIGYG KAGL P HTWL 
Sbjct  174  MYYA----GASRAGEIAVNWTSLRAAASSLNPQVVRLAFAFILIGYGTKAGLAPMHTWLP  229

Query  236  DAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLM  295
            DAHS+APAP+SALMSGVLL V    ++R + + D   G  +    LL +GL +L VA + 
Sbjct  230  DAHSEAPAPISALMSGVLLNVGLYAVMRFKVVTDIAVGAHFAGPWLLGIGLLSLTVAAIF  289

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            L V  + KRMLAYSS+EH+G+I +    G    +   LLHV+ H + K++LF+  G +  
Sbjct  290  LIVPRNYKRMLAYSSVEHVGVICLGLGFGGYWGVLGALLHVINHALSKSLLFILSGNILL  349

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
             + +T +  + G++R S L   +FA G + LLGLPPF +F SE  I R+       WV+ 
Sbjct  350  KYQTTDLRRVRGLLRASPLTAGAFAAGTLALLGLPPFGLFISEFLIFRAGVESGPLWVVI  409

Query  416  AALLLIAIGFTALARNSGRMLLGTP  440
              + L+A+ F  +  +  +ML G P
Sbjct  410  LGVALLAVIFAGMLGSVNQMLYGAP  434


>gi|338812157|ref|ZP_08624346.1| NADH dehydrogenase (quinone) [Acetonema longum DSM 6540]
 gi|337275813|gb|EGO64261.1| NADH dehydrogenase (quinone) [Acetonema longum DSM 6540]
Length=524

 Score =  281 bits (720),  Expect = 2e-73, Method: Compositional matrix adjust.
 Identities = 163/394 (42%), Positives = 233/394 (60%), Gaps = 10/394 (2%)

Query  60   GLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMV  119
            G+   DAL   ML+VIG +   A   S+ Y+  EL HGH+  R    Y  L   F+  M+
Sbjct  94   GMFYLDALNATMLLVIGTLSFTAAWFSLSYMRRELEHGHLSARMLSRYYALLQLFIFTML  153

Query  120  LAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLY  179
            + +   N+G+IWVA+EATT+ +A LV     R+ALEA WKYV++C+VGI +A LGT+LLY
Sbjct  154  VVLMVENLGLIWVAVEATTLASALLVAFYFNRSALEAAWKYVMVCTVGICLALLGTILLY  213

Query  180  FAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHS  239
            +   ++      AL+   L +HA  LDPG+ +L+   LL+GYG KAGL P HTWL DAHS
Sbjct  214  YTQVNAVGGGDHALSWLSLRDHADLLDPGLIKLSFVFLLVGYGTKAGLAPMHTWLPDAHS  273

Query  240  QAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVT  299
            QAP+PVS L+SG LL+ A   LIR   I+    GP + +  LL  G+ ++ V++  + V 
Sbjct  274  QAPSPVSGLLSGALLSCALYALIRNMIIVQGALGPLFGQQLLLAFGVISVAVSIPFVLVQ  333

Query  300  GDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDS  359
             D+KR+LAYSS+EHMGL+A+    GT LAI   L HVL H + K+ LF   G +   + +
Sbjct  334  HDLKRLLAYSSVEHMGLVALGLGIGTPLAIFGALFHVLNHALAKSSLFYLAGMITQGYHT  393

Query  360  TAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALL  419
              I  I+G++R   + G  F +GL+ + G PPF +F S+  I R+ A E     LG+++L
Sbjct  394  KYIMRISGLVREMPVTGWMFVLGLLAITGTPPFGVFTSKFVILRA-AFESGNIFLGSSVL  452

Query  420  LIAIG-FTALARNSGRMLLG--------TPAAGA  444
            ++ +  F  +     RM  G         PAAG+
Sbjct  453  VLLVAVFAGMIYYCLRMAFGQVTYKHHVQPAAGS  486


>gi|343518711|ref|ZP_08755701.1| hydrogenase 4 subunit F [Haemophilus pittmaniae HK 85]
 gi|343393626|gb|EGV06181.1| hydrogenase 4 subunit F [Haemophilus pittmaniae HK 85]
Length=512

 Score =  278 bits (711),  Expect = 1e-72, Method: Compositional matrix adjust.
 Identities = 176/479 (37%), Positives = 263/479 (55%), Gaps = 5/479 (1%)

Query  5    LLAAILAPLAASIASLITGWRRTTATLTALSAT-TVLACAVAMGFWMGSGAQFGLGGL--  61
            ++A ++APLA ++ +      +    +TAL  T  VL    A+    G  AQ  +  L  
Sbjct  6    IIALLIAPLAVALINFAVSGSKNRNLITALHVTGLVLMVIFALQVIRGVLAQNTIEALNH  65

Query  62   -LRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
                D+L+ + L +I IVGTLA   SIGY++TEL  GHID ++   Y      F   M+L
Sbjct  66   WFYVDSLSAIFLGLIAIVGTLAGVYSIGYMNTELKEGHIDFKTFGRYHGFLHLFFFTMLL  125

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            +V  NNI ++W AIEATT+ +AFLVG  + +TALEA WKY+VICSVG+A    GT+L + 
Sbjct  126  SVMTNNIILMWAAIEATTLSSAFLVGTYKQKTALEAAWKYIVICSVGVAFGLYGTILTFS  185

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
               +  A A  A+    L   AAGL+P +  +A   +L+G+G K GLFP HTWL DAHS+
Sbjct  186  GGANLLADAGDAIFWSFLNSQAAGLNPMLMYIAFAFILVGFGTKCGLFPMHTWLPDAHSE  245

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            AP+PVSA++S VLL  A  +++R   ++    G  Y +  LL  GL +  +A   + +  
Sbjct  246  APSPVSAILSAVLLNCAMLIVLRYYILVSKAVGSDYPQTLLLTFGLLSTGIASFFIIMQH  305

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KR LAY S+E+MGLI+ A   G  +   A LLH + H + K +LF A G +   + S 
Sbjct  306  DIKRKLAYHSIENMGLISFAFGLGGPIGAFAGLLHTITHSLAKALLFCASGNILLKYRSR  365

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
             I  ++G+     +  V FA G + L G+PPF MF SE AIA +       W++   L+ 
Sbjct  366  DITQVSGLWVSMPITAVLFAGGALALGGMPPFGMFTSEFAIAVAGIYAGKTWLIILCLIF  425

Query  421  IAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGIT-AGPLADLL  478
            + I    L     + +LG P        +  ++   L + +++   +G+  A P+ +LL
Sbjct  426  LTIALAGLTTMLLKTVLGKPKENIELGEINKSSVTVLAIYLLLLFMMGVYIADPILELL  484


>gi|91202883|emb|CAJ72522.1| strongly similar to membrane-bound [NiFe]-hydrogenase-4, subunit 
F [Candidatus Kuenenia stuttgartiensis]
Length=491

 Score =  277 bits (708),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 146/394 (38%), Positives = 219/394 (56%), Gaps = 3/394 (0%)

Query  56   FGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFL  115
            +GL      DAL+++   +I IVG  A   S+GY++ E+  G +  +  RLY  L   F+
Sbjct  55   YGLNEFFYMDALSILTTQIITIVGFAAALYSVGYMEEEVREGVVTEKKLRLYYFLFHMFI  114

Query  116  CAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGT  175
             +M+L    NN+G++WVAIEATT+ T FLVG    +   EA WKY+VIC+VGI +A  G 
Sbjct  115  FSMLLVCVTNNLGIMWVAIEATTLSTTFLVGFYNKKQHQEAAWKYIVICTVGITLALFGV  174

Query  176  VLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLA  235
            +L Y++++         LN   L   A   DP + +LA   +LIGYG KAGL P HTWL 
Sbjct  175  ILTYYSSKSVFGEIGHMLNWTSLLTVADRFDPHLIKLAFIFILIGYGTKAGLAPMHTWLP  234

Query  236  DAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLM  295
            DAHSQAP+P+SAL SGVLL  +   +IR   I     GP Y    L+V GL +++ ++  
Sbjct  235  DAHSQAPSPISALFSGVLLNCSLYGIIRYHIITSKCVGPHYSCTLLMVFGLISVIASIPF  294

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            + V  D KR+ AYSS+EH+G I +    G   ++    LH   H + K++LF   G L  
Sbjct  295  ILVQRDYKRLFAYSSIEHIGFITLGIGFGGMYSVYGAELHTFNHAVAKSLLFFCAGNLFL  354

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASE-LAIARSLANERLAWVL  414
             + +  +  I GV++ + + GV   + +  + G PPF +F SE L +A   ++  +  ++
Sbjct  355  KYKTRDMDSIKGVIKTTPVTGVFLIIAVFAITGTPPFGIFVSEFLVLADGFSSGNVFIII  414

Query  415  GAALLLIAIG--FTALARNSGRMLLGTPAAGAPA  446
             ++LL++ I   F     N  +M+LG P    P 
Sbjct  415  FSSLLVVCITLIFIGFINNIFKMVLGEPTTSVPK  448


>gi|260913687|ref|ZP_05920163.1| hydrogenase subunit [Pasteurella dagmatis ATCC 43325]
 gi|260632226|gb|EEX50401.1| hydrogenase subunit [Pasteurella dagmatis ATCC 43325]
Length=508

 Score =  275 bits (702),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 150/352 (43%), Positives = 214/352 (61%), Gaps = 0/352 (0%)

Query  50   MGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGV  109
            +  GA    G     D+L+ + + +IGIVG LA   SIGY+  EL  G  + +    Y  
Sbjct  52   LSQGALSTEGHWFYVDSLSAIFVGIIGIVGLLAGLYSIGYMKKELELGEFNEQQYGNYYG  111

Query  110  LTPAFLCAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIA  169
                F   M+L+V  NNI V+WV IEATT+ +AFLVG    RT+LEA WKY++ICSVG+A
Sbjct  112  FFHLFFFTMLLSVMTNNIVVMWVGIEATTLSSAFLVGAYGKRTSLEAAWKYIIICSVGVA  171

Query  170  VAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFP  229
                GT+L++  A +  A    A+    + E+A  LDP +  LA   +LIG+G K GLFP
Sbjct  172  FGLYGTLLVFADASNILADPEQAIFWTKINENATALDPHLIHLAFIFILIGFGTKCGLFP  231

Query  230  FHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATL  289
             HTWL DAHS+AP+PVSA++SG+LL  A  V++R   + +   GP + +N LL+ G+ ++
Sbjct  232  MHTWLPDAHSEAPSPVSAILSGILLNCAMLVVLRYYILTNKAVGPEFAQNLLLIFGIISV  291

Query  290  LVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLA  349
             +A L +    D+KR+LAYSS+E+MGLIA+    G  L + A LLH + H + KT+LF A
Sbjct  292  AIAALFIIAQRDIKRLLAYSSIENMGLIAVGFGIGGPLGVFAGLLHTINHSLAKTLLFCA  351

Query  350  GGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAI  401
             G +   + S  + DI G+ +   +  V FA G + L G+PPF +F SELA+
Sbjct  352  SGNILVKYHSRDMQDIKGLWKTMPITAVLFAGGALALSGVPPFNLFISELAL  403


>gi|251792880|ref|YP_003007606.1| hydrogenase-4 subunit F [Aggregatibacter aphrophilus NJ8700]
 gi|247534273|gb|ACS97519.1| hydrogenase-4 component F [Aggregatibacter aphrophilus NJ8700]
Length=512

 Score =  275 bits (702),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 168/444 (38%), Positives = 247/444 (56%), Gaps = 6/444 (1%)

Query  5    LLAAILAPLAASIASLITGWRRTTATLTALSAT-TVLACAVAMGFWMG---SGAQFGLGG  60
            ++A ++APLA S+AS      +T    TAL  T  +L  A ++    G    G    LG 
Sbjct  6    IIALLIAPLAISLASFACSVTKTRTICTALHVTGLILMFAFSLQVITGVLTQGEISSLGN  65

Query  61   LLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRS-ARLYGVLTPAFLCAMV  119
             +  D+L+ + L +I +VG LA   SI YI+ E   GHID ++    YG L   F   M+
Sbjct  66   WIHVDSLSAIFLALISVVGGLAGVYSIAYINREFNEGHIDLKTYCNYYGFLH-LFFFTMI  124

Query  120  LAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLY  179
            L+V  NN+ ++W  IEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L +
Sbjct  125  LSVTTNNLILMWAGIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLFGTILTF  184

Query  180  FAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHS  239
                +  A  + A+    + + A+ L  G+  LA   +L+G+G K GLFP HTWL DAHS
Sbjct  185  SNGTNLLADPSQAIFWTAVNQQASDLHHGLMYLAFAFILVGFGTKCGLFPMHTWLPDAHS  244

Query  240  QAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVT  299
            +AP+PVSA++S VLL  A  V++R   ++    G  Y +  +LV GL +  VA   + + 
Sbjct  245  EAPSPVSAVLSAVLLNCAMLVVLRYYILVSKAVGSDYPQTLMLVFGLLSTGVASFFIIMQ  304

Query  300  GDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDS  359
             D+KR LAY S+E+MGLI+ A   G  +   A LLH + H + K +LF A G +   + S
Sbjct  305  HDIKRKLAYHSIENMGLISFAFGLGGPVGAFAGLLHTITHSLAKALLFCASGNILLKYRS  364

Query  360  TAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALL  419
              I +++G+ R      V FA G + L G+PPF MF SE AIA +       W++   L+
Sbjct  365  RDIHEVSGLWRTMPFTAVLFAGGALALGGMPPFGMFTSEFAIAVAGIYAGKTWLIVLCLI  424

Query  420  LIAIGFTALARNSGRMLLGTPAAG  443
             + I    L     + +LG P  G
Sbjct  425  FLTIALAGLTTMLLKTVLGKPKEG  448


>gi|293392058|ref|ZP_06636392.1| hydrogenase-4 component F [Aggregatibacter actinomycetemcomitans 
D7S-1]
 gi|290952592|gb|EFE02711.1| hydrogenase-4 component F [Aggregatibacter actinomycetemcomitans 
D7S-1]
Length=512

 Score =  274 bits (701),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 172/439 (40%), Positives = 256/439 (59%), Gaps = 4/439 (0%)

Query  5    LLAAILAPLAASIASLITGWRRTTATLTALSAT-TVLACAVAMGFWMGSGAQFGLGGL--  61
            ++A + APLA ++A       +     TAL  T  +L    A+    G   Q  +  L  
Sbjct  6    IIALLTAPLAVALACFACRSTKNRTICTALHVTGLILMVGFALQIINGVLTQSDISALNN  65

Query  62   -LRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVL  120
             +  D+L+ + L +I +VGTLA   SIGYI TEL  GH++ +    Y      F   M++
Sbjct  66   WVYIDSLSAIFLGLIAVVGTLAGIYSIGYIGTELQEGHLNLKDFCNYHGFLHLFFFTMII  125

Query  121  AVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYF  180
            +V  NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L + 
Sbjct  126  SVITNNVILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTILTFA  185

Query  181  AARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQ  240
               +  A  + A+    L + AAGL+P +  +A   +LIG+G K GLFP HTWL+DAHS+
Sbjct  186  NGNNLLADPSQAIFWSALNQQAAGLNPMLMYIAFAFILIGFGTKCGLFPMHTWLSDAHSE  245

Query  241  APAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTG  300
            AP+PVSA++S VLL  A  V++R   ++    G AY +  LLV GL ++LVA L + V  
Sbjct  246  APSPVSAILSAVLLNCAMLVVLRYYILVSKAVGSAYPQTLLLVFGLLSVLVAALFIIVQF  305

Query  301  DVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDST  360
            D+KR+LAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   + + 
Sbjct  306  DIKRLLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKYKTR  365

Query  361  AIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLL  420
             +  + G+ R + +  V FA G + L GLPPF +F SE +IA +       W++   L+L
Sbjct  366  DMNQVRGLWRVAPVSAVLFAGGALALGGLPPFNVFVSEFSIAVAGIYAGKTWLVIFCLIL  425

Query  421  IAIGFTALARNSGRMLLGT  439
            + I    LA    + +LG 
Sbjct  426  LTIVLAGLALMILKTVLGK  444


>gi|261868402|ref|YP_003256324.1| hydrogenase-4 subunit F [Aggregatibacter actinomycetemcomitans 
D11S-1]
 gi|261413734|gb|ACX83105.1| hydrogenase-4 component F [Aggregatibacter actinomycetemcomitans 
D11S-1]
Length=512

 Score =  273 bits (698),  Expect = 4e-71, Method: Compositional matrix adjust.
 Identities = 171/442 (39%), Positives = 256/442 (58%), Gaps = 10/442 (2%)

Query  5    LLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMG-------SGAQFG  57
            ++A + APLA ++A       R+T   T  +A  V    + +GF +         G    
Sbjct  6    IIALLTAPLAVALACFAC---RSTKNRTICTALHVTGLILMVGFALQIINGVLTQGDISA  62

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
            L   +  D+L+ + L +I +VGTLA   SIGYI TEL  GH+  +    Y      F   
Sbjct  63   LNNWVYIDSLSAIFLGLIAVVGTLAGVYSIGYIGTELQEGHLSLKDFYNYHGFLHLFFFT  122

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M+++V  NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L
Sbjct  123  MIISVITNNVILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTIL  182

Query  178  LYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADA  237
             +    +  A  + A+    L + AAGL+P +  +A   +LIG+G K GLFP HTWL+DA
Sbjct  183  TFANGNNLLADPSQAIFWSALNQQAAGLNPMLMYIAFVFILIGFGTKCGLFPMHTWLSDA  242

Query  238  HSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLT  297
            HS+AP+PVSA++S VLL  A  V++R   ++    G +Y +  LLV GL ++LVA L + 
Sbjct  243  HSEAPSPVSAILSAVLLNCAMLVVLRYYILVSKAVGSSYPQTLLLVFGLLSVLVAALFII  302

Query  298  VTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAH  357
            V  D+KR+LAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   +
Sbjct  303  VQFDIKRLLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKY  362

Query  358  DSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAA  417
             +  +  + G+ R + +  V FA G + L GLPPF +F SE +IA +       W++   
Sbjct  363  KTRDMNQVRGLWRVAPVSAVLFAGGALALGGLPPFNVFVSEFSIAVAGIYAGKTWLVIFC  422

Query  418  LLLIAIGFTALARNSGRMLLGT  439
            L+L+ I    LA    + +LG 
Sbjct  423  LILLTIVLAGLALMIMKTVLGK  444


>gi|345430346|ref|YP_004823467.1| hydrogenase 4, membrane subunit [Haemophilus parainfluenzae T3T1]
 gi|301156410|emb|CBW15881.1| hydrogenase 4, membrane subunit [Haemophilus parainfluenzae T3T1]
Length=512

 Score =  272 bits (695),  Expect = 1e-70, Method: Compositional matrix adjust.
 Identities = 165/445 (38%), Positives = 245/445 (56%), Gaps = 8/445 (1%)

Query  5    LLAAILAPLAASIASLITGWRRTTATLTALSAT-----TVLACAVAMGFWMGSGAQFGLG  59
            ++A ++APLA S+AS   G  +     TAL  T      V +  V  G  +  G     G
Sbjct  6    IIALLIAPLAISLASFACGVTKARTICTALHVTGLILMFVFSLQVITGV-LTQGEINCFG  64

Query  60   GLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRS-ARLYGVLTPAFLCAM  118
              +  D+L+ + L +I +VG LA   SI YI+ E   GH+D ++    YG L   F   M
Sbjct  65   NWIHVDSLSAIFLALISVVGGLAGVYSIAYINREFNEGHVDLKTYCNYYGFLH-LFFFTM  123

Query  119  VLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLL  178
            +L+V  NN+ ++W  IEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L 
Sbjct  124  ILSVTTNNLILMWAGIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLFGTILT  183

Query  179  YFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAH  238
            +    +  A  + A+    + + A  L+ G+  LA   +L+G+G K GLFP HTWL DAH
Sbjct  184  FSNGTNLLADPSQAIFWTAVNQQAGELNHGLMYLAFAFILVGFGTKCGLFPMHTWLPDAH  243

Query  239  SQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTV  298
            S+AP+PVSA++S VLL  A  V++R   ++    G  Y +  +LV GL +  +A   + +
Sbjct  244  SEAPSPVSAVLSAVLLNCAMLVVLRYYILVSKAVGADYPQTLMLVFGLLSTGIASFFIIM  303

Query  299  TGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHD  358
              D+KR LAY S+E+MGLI+ A   G  +   A LLH + H + K +LF A G +   + 
Sbjct  304  QHDIKRKLAYHSIENMGLISFAFGLGGPVGAFAGLLHTITHSLAKALLFCASGNILLKYR  363

Query  359  STAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAAL  418
            S  I +++G+ R      V FA G + L G+PPF MF SE AIA +       W++   L
Sbjct  364  SRDIHEVSGLWRTMPFTAVLFAGGALALGGMPPFGMFTSEFAIAVAGIYAGKTWLIVLCL  423

Query  419  LLIAIGFTALARNSGRMLLGTPAAG  443
            + + I    L     + +LG P  G
Sbjct  424  IFLTIALAGLTTMLLKTVLGKPKEG  448


>gi|312110877|ref|YP_003989193.1| NADH/Ubiquinone/plastoquinone (complex I) [Geobacillus sp. Y4.1MC1]
 gi|336235309|ref|YP_004587925.1| NADH dehydrogenase (quinone) [Geobacillus thermoglucosidasius 
C56-YS93]
 gi|311215978|gb|ADP74582.1| NADH/Ubiquinone/plastoquinone (complex I) [Geobacillus sp. Y4.1MC1]
 gi|335362164|gb|AEH47844.1| NADH dehydrogenase (quinone) [Geobacillus thermoglucosidasius 
C56-YS93]
Length=495

 Score =  271 bits (693),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 156/390 (40%), Positives = 219/390 (57%), Gaps = 0/390 (0%)

Query  56   FGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFL  115
            F L G+L AD LT +++++IG++G L    SIGY+  EL HG  + +    Y      FL
Sbjct  61   FALDGMLFADELTAILILLIGVIGFLNGFYSIGYMRHELTHGEENEKGVCFYYGFYHIFL  120

Query  116  CAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGT  175
              MV++  +NNI ++WVA+EATT+ +AFLVG  + +T+ E  WKYV+ICSVG+A A  GT
Sbjct  121  FTMVISAISNNIAIMWVAVEATTLGSAFLVGFYKHKTSAEGAWKYVLICSVGLAFALYGT  180

Query  176  VLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLA  235
            +L Y  A  S   A  A+    L      LDP + +LA   +LIG+G KAGLFP HTWL 
Sbjct  181  ILTYSNAFSSVQDAHRAMLWTELVRMGQDLDPQLMKLAFVFVLIGFGTKAGLFPMHTWLP  240

Query  236  DAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLM  295
            DAHS+AP+P SAL+SGVLL  A   ++R   I   V G  +  + LL+ GL T+ VA   
Sbjct  241  DAHSEAPSPASALLSGVLLKCALFAIVRYYAIALQVVGKEFPNSLLLIFGLLTVGVAAFF  300

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            + +  D+KR LAYSS+EH+G+IA     G  L I A LLH + H I K++LF   G +  
Sbjct  301  ILMQNDIKRKLAYSSVEHVGIIATGLGIGGALGIFASLLHTINHSITKSLLFCTTGNIMM  360

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
             + +     I G+++      + F  G+I + G PPF +F SE     +       W + 
Sbjct  361  KYGTRDANKIRGMLKVMPFTALMFMAGIIAVAGSPPFNIFVSEFTTLTAGLKSGHFWAMI  420

Query  416  AALLLIAIGFTALARNSGRMLLGTPAAGAP  445
              LL + I F AL       + G P+   P
Sbjct  421  LFLLFLVIAFVALVLLISETVFGPPSEDLP  450


>gi|220929110|ref|YP_002506019.1| NADH/Ubiquinone/plastoquinone (complex I) [Clostridium cellulolyticum 
H10]
 gi|219999438|gb|ACL76039.1| NADH/Ubiquinone/plastoquinone (complex I) [Clostridium cellulolyticum 
H10]
Length=495

 Score =  269 bits (688),  Expect = 8e-70, Method: Compositional matrix adjust.
 Identities = 152/426 (36%), Positives = 239/426 (57%), Gaps = 6/426 (1%)

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
               +   D+L+  +L +  +   L +  SI Y   EL +  I  R  +LY  L+ AF+ +
Sbjct  59   FKNIFYMDSLSGYILFITTLAFFLVSLYSISYFGQELKNKVITIRKLKLYYSLSNAFVLS  118

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M+LA+   N+GV+W++IEATT+ +AFLVG    + A+EA WKY++ICSVGI  A LG +L
Sbjct  119  MILALTTRNMGVMWISIEATTLASAFLVGFYNNKRAIEAAWKYLIICSVGITFALLGIIL  178

Query  178  LYFAAR-DSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLAD  236
            L++++    G A    ++   L ++A+ LDP + ++A   +LIG+G K G  P HTWL D
Sbjct  179  LFYSSTVKLGGARISGMDWSYLIKYASALDPSILKIAFIFILIGFGTKVGFSPMHTWLPD  238

Query  237  AHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPA-YLRNGLLVVGLATLLVAVLM  295
            AHSQAP+PVSAL+SGVLL  A   +IR+  I++   G + Y  N L+V+ + ++  A + 
Sbjct  239  AHSQAPSPVSALLSGVLLNTAMYGVIRVMSIVNKCLGSSNYTGNLLIVLSVLSIGTAAVF  298

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            + V  D KR+LAYSS+EHMG+IA+     T ++I A L H   H + K +LFLA G +  
Sbjct  299  ILVQQDYKRILAYSSIEHMGIIALGLGVCTPISIFAALYHTFNHAMTKLMLFLATGNVYL  358

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
             H +  I+ I G+++   + G+ F +G   + G+PPF +F SE          +   V  
Sbjct  359  KHHTKKISSIRGLIKTMPVTGIVFVLGTFAITGMPPFGVFMSEFNTVVGTIFSKRYIVTA  418

Query  416  AALLLIAIGFTALARNSGRMLLG---TPAAGAPAITVPATAAAALMVGIVVSAALGITAG  472
              L+ +++ F    +  G+M  G    P      I +   A   +++ I V A + I   
Sbjct  419  LLLIFLSMVFAGFTKQLGKMFYGNNSNPQIKKGEIDIIGPAVLIILLCITVLAGIYIPV-  477

Query  473  PLADLL  478
            P  +L+
Sbjct  478  PFKELM  483


>gi|147919459|ref|YP_686801.1| hydrogenase, membrane subunit 1-like protein (EchA-like) [uncultured 
methanogenic archaeon RC-I]
 gi|110622197|emb|CAJ37475.1| hydrogenase, membrane subunit 1-like protein (EchA-like) [uncultured 
methanogenic archaeon RC-I]
Length=487

 Score =  268 bits (684),  Expect = 2e-69, Method: Compositional matrix adjust.
 Identities = 164/435 (38%), Positives = 243/435 (56%), Gaps = 1/435 (0%)

Query  9    ILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALT  68
            ++ PL  +    +   +RT   ++ L A  ++A  V + + + +      GGL   D+L 
Sbjct  7    LIIPLITAALCYLIKHKRTVEIVSTLGALAIMAGCVYLAYTVFTRGPVS-GGLWYVDSLG  65

Query  69   VVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIG  128
              MLV+I  +G  A   SIGY+  E     ID    R Y      F+  M+L   ++N+G
Sbjct  66   AYMLVIISFIGLAAAIYSIGYLGYEYKEKKIDLGRLRYYFTFFHVFIFTMLLVCTSSNLG  125

Query  129  VIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAA  188
            ++W+AIEATT+ +AFLVG     T++EA WKY++ICSVGI +A LGT+LLY ++ ++   
Sbjct  126  IMWIAIEATTLASAFLVGFYNKDTSVEAAWKYIIICSVGITLALLGTILLYASSVNTLGE  185

Query  189  AAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSAL  248
            +A ALN  +LAE A  LDP + ++A  L++IGYG KAG  P HTWL DAHS+AP P+S L
Sbjct  186  SADALNWPMLAEKAKSLDPTLLKIAFILVIIGYGTKAGFAPMHTWLPDAHSEAPTPISGL  245

Query  249  MSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAY  308
            +SGVLL  A   ++R   I     GP +    L+V GL +L  A   + +  D KR+LAY
Sbjct  246  LSGVLLNCAMYGILRYHIITTNALGPDFSGTLLIVFGLLSLAAAAAFIIIQKDYKRLLAY  305

Query  309  SSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGV  368
            SS+EHMG+IAI    G  + I   LLH+L H + K+++F   G +     +  I ++ G+
Sbjct  306  SSIEHMGIIAIGFGIGGAVGIFGALLHILNHAVTKSLMFFGAGNILLKFKTKNIDEVKGI  365

Query  369  MRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFTAL  428
                    + F  G + + G PPF++F SE+ I  +   +    V    LLL+ I F   
Sbjct  366  AALMPWTAMCFVAGALAITGSPPFSIFVSEIIILIAGFTQGNIVVSVLYLLLLVIIFAGF  425

Query  429  ARNSGRMLLGTPAAG  443
              + GRM+ G PA G
Sbjct  426  MYHVGRMVFGEPAPG  440


>gi|341948990|gb|EGT75605.1| hydrogenase-4 component F [Haemophilus haemolyticus M19501]
Length=512

 Score =  265 bits (678),  Expect = 9e-69, Method: Compositional matrix adjust.
 Identities = 160/430 (38%), Positives = 252/430 (59%), Gaps = 1/430 (0%)

Query  50   MGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGV  109
            +  G+       +  D+L+ + L +I +VG+LA   SIGY++TEL  GHID ++   Y  
Sbjct  55   LEKGSVSAFNNWVYVDSLSAIFLGLIAVVGSLAGVYSIGYMNTELEEGHIDFKTYAHYHG  114

Query  110  LTPAFLCAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIA  169
                F   M+++V  NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A
Sbjct  115  FLHLFFFTMIVSVITNNLILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVA  174

Query  170  VAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFP  229
                GT+L +  A    A  + A+    + + A GL+P +  +A   +LIG+G K GLFP
Sbjct  175  FGLYGTLLTFANANGVLADPSQAIFWSAVNQQATGLNPMLMYIAFAFVLIGFGTKCGLFP  234

Query  230  FHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATL  289
             HTWL+DAHS+AP+PVSA++S VLL  A  V++R   ++    G  + +  +L+ GL ++
Sbjct  235  MHTWLSDAHSEAPSPVSAILSAVLLNCAMLVVLRYYTLVSKAVGAEFPQTLMLIFGLLSV  294

Query  290  LVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLA  349
            LVA L + V  D+KR+LAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A
Sbjct  295  LVAALFIIVQFDIKRLLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLVKTLLFCA  354

Query  350  GGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANER  409
             G +   + +  +  + G+ R + +  V FA G + L G+PPF +F SE ++  +     
Sbjct  355  SGNILLKYKTRDMNQVRGLWRVAPVSAVLFAGGALALGGIPPFNVFVSEFSVVVAGITAG  414

Query  410  LAWVLGAALLLIAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGI  469
              W++   L+L+ I    LA    + +LG       A  V   + AA+ + +++   +GI
Sbjct  415  KTWLVILCLILLTIVLAGLALMLLKTVLGKQPDNVEAGEVSKVSLAAMTILLLLMFVMGI  474

Query  470  -TAGPLADLL  478
              A P+  LL
Sbjct  475  HIAEPILQLL  484


>gi|341956341|gb|EGT82771.1| hydrogenase-4 component F [Haemophilus haemolyticus M21639]
Length=512

 Score =  265 bits (677),  Expect = 1e-68, Method: Compositional matrix adjust.
 Identities = 153/393 (39%), Positives = 235/393 (60%), Gaps = 6/393 (1%)

Query  5    LLAAILAPLAASIASL-ITGWR-RTTAT---LTALSATTVLACAVAMGFWMGSGAQFGLG  59
            ++A ++APL  +  S  + G + RT  T   +T L      +  V  G  +  G+     
Sbjct  6    IIALLIAPLVIAFESFALRGTKNRTVCTAFHITGLILMLFFSVQVISGV-LEKGSISAFN  64

Query  60   GLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMV  119
              +  D+L+ + L +I +VG+LA   SIGY++TEL  GHID ++   Y      F   M+
Sbjct  65   NWVYVDSLSAIFLGLIAVVGSLAGVYSIGYMNTELEEGHIDFKTYAHYHGFLHLFFFTMI  124

Query  120  LAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLY  179
            ++V  NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L +
Sbjct  125  VSVITNNLILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTLLTF  184

Query  180  FAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHS  239
              A    A  + A+    + + A GL+P +  +A   +LIG+G K GLFP HTWL+DAHS
Sbjct  185  ANANGVLADPSQAIFWSAVNQQATGLNPMLMYIAFAFVLIGFGTKCGLFPMHTWLSDAHS  244

Query  240  QAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVT  299
            +AP+PVSA++S VLL  A  V++R   ++    G  + +  +L+ GL ++LVA L + V 
Sbjct  245  EAPSPVSAILSAVLLNCAMLVVLRYYTLVSKAVGAEFSQTLMLIFGLLSVLVAALFIIVQ  304

Query  300  GDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDS  359
             D+KRMLAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   + +
Sbjct  305  FDIKRMLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKYKT  364

Query  360  TAIADITGVMRRSRLIGVSFAVGLIVLLGLPPF  392
              +  + G+ R + +  V FA G + L G+PPF
Sbjct  365  RDMNQVRGLWRVAPVSAVLFAGGALALGGIPPF  397


>gi|341949807|gb|EGT76406.1| hydrogenase-4 component F [Haemophilus haemolyticus M21127]
Length=512

 Score =  265 bits (676),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 139/328 (43%), Positives = 209/328 (64%), Gaps = 0/328 (0%)

Query  65   DALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCA  124
            D+L+ + L +I +VG+LA   SIGY++TEL  GHID ++   Y      F   M+++V  
Sbjct  70   DSLSAIFLGLIAVVGSLAGVYSIGYMNTELEEGHIDFKTYAHYHGFLHLFFFTMIVSVIT  129

Query  125  NNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARD  184
            NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L +  A  
Sbjct  130  NNLILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTLLTFANANG  189

Query  185  SGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAP  244
              A  + A+    + + A GL+P +  +A   +LIG+G K GLFP HTWL+DAHS+AP+P
Sbjct  190  VLADPSQAIFWSAVNQQATGLNPMLMYIAFAFVLIGFGTKCGLFPMHTWLSDAHSEAPSP  249

Query  245  VSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKR  304
            VSA++S VLL  A  V++R   ++    G  + +  +L+ GL ++LVA L + V  D+KR
Sbjct  250  VSAILSAVLLNCAMLVVLRYYTLVSKAVGAEFPQTLMLIFGLLSVLVAALFIIVQFDIKR  309

Query  305  MLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIAD  364
            MLAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   + +  +  
Sbjct  310  MLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKYKTRDMNQ  369

Query  365  ITGVMRRSRLIGVSFAVGLIVLLGLPPF  392
            + G+ R + +  V FA G + L G+PPF
Sbjct  370  VRGLWRVAPVSAVLFAGGALALGGIPPF  397


>gi|238749932|ref|ZP_04611436.1| Hydrogenase-4 component F [Yersinia rohdei ATCC 43380]
 gi|238711861|gb|EEQ04075.1| Hydrogenase-4 component F [Yersinia rohdei ATCC 43380]
Length=545

 Score =  265 bits (676),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 153/384 (40%), Positives = 222/384 (58%), Gaps = 5/384 (1%)

Query  18   ASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVIGI  77
            A + T W   T     L     + C VA+G     G        L  D+L+ + L ++GI
Sbjct  31   ARMATTWVHFTGITLLLVVALTVVCRVALG-----GDILAAHNWLHIDSLSALFLAILGI  85

Query  78   VGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAIEAT  137
            +G +    S+GY+  E+ +G I   +   Y      FL  M+L V +NN+ ++WV IEAT
Sbjct  86   IGFITGLYSLGYMRHEVNNGEITVSTLCNYYGFFHLFLFTMLLVVTSNNLILMWVGIEAT  145

Query  138  TVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDI  197
            T+ +AFLVG    R++LEA WKY++IC+VG+A    GTVL+Y  A +  +    A+   +
Sbjct  146  TLSSAFLVGLYGQRSSLEAAWKYIIICTVGVAFGLYGTVLVYANAANVLSDPGSAIFWTV  205

Query  198  LAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVA  257
            +AEHA  LDP +  LA   +LIG+G K GLFP H+WL DAHS+AP+P SAL+S VLL  A
Sbjct  206  VAEHAKELDPTLMHLAFVFILIGFGTKTGLFPMHSWLPDAHSEAPSPTSALLSAVLLNCA  265

Query  258  FSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLI  317
              V+IR   I+ A  GP + +  LLV G+ ++ V+   +    D+KR+LAYSS+E+MGLI
Sbjct  266  LLVIIRYYIIISAAIGPHFPQMLLLVFGMMSVAVSAFFILAQRDMKRLLAYSSVENMGLI  325

Query  318  AIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGV  377
            A+A   G  L + A L H L H + KT+LF   G +   + +  +  I G++R + L  V
Sbjct  326  AVALGIGGPLGVLAALFHTLNHSLAKTLLFCGSGNVLLKYGTRDMGAIKGIIRVAPLTAV  385

Query  378  SFAVGLIVLLGLPPFAMFASELAI  401
             FA G + L G+PPF +F SE  +
Sbjct  386  MFAGGALALAGMPPFNVFISEFMV  409


>gi|326202173|ref|ZP_08192043.1| NADH/Ubiquinone/plastoquinone (complex I) [Clostridium papyrosolvens 
DSM 2782]
 gi|325987968|gb|EGD48794.1| NADH/Ubiquinone/plastoquinone (complex I) [Clostridium papyrosolvens 
DSM 2782]
Length=495

 Score =  264 bits (675),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 146/383 (39%), Positives = 223/383 (59%), Gaps = 2/383 (0%)

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
               L   D+L+  +L +  +   L +  SI Y   EL    I     +LY  L+ AF+ +
Sbjct  59   FKNLFYMDSLSGYILFITTLAFFLVSLYSISYFGQELKKKVITIGKLKLYYSLSNAFVLS  118

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M+LA+   N+GV+W++IEATT+ +AFLVG    + A+EA WKY++ICSVGIA A LG +L
Sbjct  119  MILALTTRNMGVMWISIEATTLASAFLVGFYNNKRAIEAAWKYLIICSVGIAFALLGIIL  178

Query  178  LYFAAR-DSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLAD  236
            L++++    G A    L+   L ++AA LDP + ++A   +LIG+G K G  P HTWL D
Sbjct  179  LFYSSTVKLGGARISGLDWSYLIKYAAALDPSILKIAFIFILIGFGTKVGFSPMHTWLPD  238

Query  237  AHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPA-YLRNGLLVVGLATLLVAVLM  295
            AHSQAP+PVSAL+SGVLL  A   +IR+  I++   G + Y  N L+V+ + ++  A + 
Sbjct  239  AHSQAPSPVSALLSGVLLNTAMYGVIRVMSIVNKCLGSSNYTGNLLIVLSVLSIGTAAVF  298

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            + V  D KR+LAYSS+EHMG+IA+     T ++I A L H+  H + K +LFLA G +  
Sbjct  299  ILVQQDYKRILAYSSIEHMGIIALGLGICTPVSIFAALYHIFNHAMTKLMLFLATGNVYL  358

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
             H +  I+ I G+++   + G+ F +G   + G+PPF +F SE          +   V  
Sbjct  359  KHHTKKISSIHGLIKTMPVTGIVFVLGTFAITGMPPFGVFMSEFNTVVGALFAKKYLVTA  418

Query  416  AALLLIAIGFTALARNSGRMLLG  438
              L+ +++ F    +  G+M  G
Sbjct  419  LLLIFLSMVFAGFTKQLGKMFYG  441


>gi|83591011|ref|YP_431020.1| hydrogenase 4 subunit F [Moorella thermoacetica ATCC 39073]
 gi|83573925|gb|ABC20477.1| NADH dehydrogenase (quinone) [Moorella thermoacetica ATCC 39073]
Length=495

 Score =  264 bits (675),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 155/388 (40%), Positives = 222/388 (58%), Gaps = 0/388 (0%)

Query  56   FGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFL  115
            F L  +L AD+LT +++++IG++G L    SIGY+  +L HG  D RS   Y      FL
Sbjct  61   FALNQMLYADSLTAILVLIIGVLGFLDGFYSIGYLRHDLEHGEADERSVCSYYGFFHIFL  120

Query  116  CAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGT  175
              M+L+  +NNI ++W A+EATT+ +AFLVG  + +T+ E  WKYV+ICSVG+A A  GT
Sbjct  121  FTMLLSAISNNIAIMWAAVEATTLGSAFLVGFYKYKTSAEGAWKYVLICSVGLAFALYGT  180

Query  176  VLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLA  235
            +L Y  A      A  A+    +A  A  LDP V +LA   +L+G+G KAGLFP HTWL 
Sbjct  181  ILTYSDAFTILQDAHRAMLWTEIAGMAHSLDPQVMKLAFVFILLGFGTKAGLFPMHTWLP  240

Query  236  DAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLM  295
            DAHS+AP+P SA++SGVLL  A   +IR   I   V G ++ +  LL+ GL ++ VA   
Sbjct  241  DAHSEAPSPASAMLSGVLLKCALFAIIRYYAIALQVLGRSFPQTLLLIFGLLSVCVAAFF  300

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            + V  D+KR LAYSS+EH+G+I      G  L I A LLH + H I K++LF A G +  
Sbjct  301  ILVQNDIKRKLAYSSVEHIGIITTGLGVGGALGIFAALLHAINHSITKSLLFCASGNVVI  360

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
             + +     I G+++ +   G+ F  GL+ + G PP  +F SE     +       W + 
Sbjct  361  KYGTRDSQKIRGLLKVAPFTGLMFMAGLLTVAGSPPLNIFVSEFMTLTAGLKGGYLWPMI  420

Query  416  AALLLIAIGFTALARNSGRMLLGTPAAG  443
              L+ + I F AL       + G+P  G
Sbjct  421  LLLIALVIVFAALVILISGSVFGSPPEG  448


>gi|325288317|ref|YP_004264498.1| NADH dehydrogenase (quinone) [Syntrophobotulus glycolicus DSM 
8271]
 gi|324963718|gb|ADY54497.1| NADH dehydrogenase (quinone) [Syntrophobotulus glycolicus DSM 
8271]
Length=486

 Score =  263 bits (673),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 149/385 (39%), Positives = 224/385 (59%), Gaps = 6/385 (1%)

Query  58   LGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCA  117
            LG  +  DAL+  ++ +I ++G L    S+GY+  ++    I+    + Y      F+  
Sbjct  56   LGRYIYIDALSAFIISIISVIGLLTAIFSLGYLSKDVEEREIEAGRLKWYYFWFYIFIFT  115

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M   V A N+G++WV+IEATT+ +A LVG    +++LEA WKY++IC+VGI  A  GT+L
Sbjct  116  MFCVVMAGNMGIMWVSIEATTLASALLVGFYDKKSSLEAAWKYIIICTVGIIFALFGTIL  175

Query  178  LYFAARDSGAAAAGALNLDILA--EHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLA  235
            L++AA    +    +L+LD L+  E+A  LDP + +LA    L+GYG KAGL P HTWL 
Sbjct  176  LHYAAV---SVTGESLSLDWLSIVENAEKLDPKLLKLAFVFALVGYGTKAGLAPMHTWLP  232

Query  236  DAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLM  295
            DAHSQAPAPVSA++SGVLL  A   ++R   I     G  +  + LL  GL ++L+A+  
Sbjct  233  DAHSQAPAPVSAILSGVLLNCALYGILRFHLIAVKPLG-MFSHDLLLFFGLISILIAMPF  291

Query  296  LTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQA  355
            +    D+KR+LAYSS+EHMGLI  A   G+  A+    LH+L H   K+ LF   G +  
Sbjct  292  IIAQHDLKRLLAYSSIEHMGLITFAVGIGSKPALYGAFLHMLNHAFTKSFLFFGAGNITQ  351

Query  356  AHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLG  415
               S  I  I G ++     G++F +G   + GLPPF++F SE  I  +  +    W  G
Sbjct  352  YFRSKKIGKIKGAIKAMPRSGLAFFIGAFAIAGLPPFSIFLSEFIIFSAGFSAGRIWHSG  411

Query  416  AALLLIAIGFTALARNSGRMLLGTP  440
              L+ +++ FT +   +G+++LG P
Sbjct  412  LVLIFVSLIFTGIIYAAGKIVLGDP  436


>gi|342903801|ref|ZP_08725605.1| hydrogenase-4 component F [Haemophilus haemolyticus M21621]
 gi|341954381|gb|EGT80865.1| hydrogenase-4 component F [Haemophilus haemolyticus M21621]
Length=512

 Score =  263 bits (672),  Expect = 5e-68, Method: Compositional matrix adjust.
 Identities = 138/328 (43%), Positives = 209/328 (64%), Gaps = 0/328 (0%)

Query  65   DALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCA  124
            D+L+ + L +I +VG+LA   SIGY++TEL  GHID ++   Y      F   M+++V  
Sbjct  70   DSLSAIFLGLIAVVGSLAGVYSIGYMNTELEEGHIDFKTYAHYHGFLHLFFFTMIVSVIT  129

Query  125  NNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARD  184
            NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L +  A  
Sbjct  130  NNLILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTLLTFANANG  189

Query  185  SGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAP  244
              A  + A+    + + A GL+P +  +A   +LIG+G K GLFP HTWL+DAHS+AP+P
Sbjct  190  VLADPSQAIFWSAVNQQATGLNPMLMYIAFAFVLIGFGTKCGLFPMHTWLSDAHSEAPSP  249

Query  245  VSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKR  304
            VSA++S VLL  A  V++R   ++    G  + +  +L+ GL ++LVA L + V  D+KR
Sbjct  250  VSAILSAVLLNCAMLVVLRYYTLVSKAVGAEFPQTLMLIFGLLSVLVAALFIIVQFDIKR  309

Query  305  MLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIAD  364
            +LAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   + +  +  
Sbjct  310  LLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKYKTRDMNQ  369

Query  365  ITGVMRRSRLIGVSFAVGLIVLLGLPPF  392
            + G+ R + +  V FA G + L G+PPF
Sbjct  370  VRGLWRVAPVSAVLFAGGALALGGIPPF  397


>gi|334341775|ref|YP_004546755.1| NADH/Ubiquinone/plastoquinone (complex I) [Desulfotomaculum ruminis 
DSM 2154]
 gi|334093129|gb|AEG61469.1| NADH/Ubiquinone/plastoquinone (complex I) [Desulfotomaculum ruminis 
DSM 2154]
Length=493

 Score =  263 bits (672),  Expect = 5e-68, Method: Compositional matrix adjust.
 Identities = 160/387 (42%), Positives = 236/387 (61%), Gaps = 7/387 (1%)

Query  59   GGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHI-DGRSARLYGVLTPAFLCA  117
            G LL  D L+ V++ +IG+VGTL    S+ Y+ T+L +G + + +  R +G+L   F+  
Sbjct  57   GSLLVIDELSAVLVFIIGMVGTLCCLYSVQYLRTDLKNGELTENKIGRFFGLLH-FFIAT  115

Query  118  MVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVL  177
            M L+V A+N+G++WVAIE TT+++A LV     + ALEA WKY++IC+VGIA A LG +L
Sbjct  116  MYLSVLADNLGLMWVAIEGTTIVSALLVAFYGHKAALEAAWKYIIICTVGIAFAMLGIIL  175

Query  178  LYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADA  237
             ++AAR+   +   +L+   L   AA LDP V +LA   +L+GYG KAGLFP HTWL DA
Sbjct  176  TFYAAREILGSGDISLSWRSLYPVAASLDPSVMKLAFIFVLVGYGTKAGLFPLHTWLPDA  235

Query  238  HSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLT  297
            HSQAP+PVSAL+SGVLL  A   ++R   +    +G  +  + L++ GL ++  AV  + 
Sbjct  236  HSQAPSPVSALLSGVLLNCAIYAIVRFHLLTSLSAGSGFSGHLLMIFGLISMAAAVPFIL  295

Query  298  VTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAH  357
            V  D+KR+LAYSS+EH+G+I +    G  L     +LH++ H + K+ LFL  G L   +
Sbjct  296  VQKDIKRLLAYSSVEHVGIIVLGLGLGGVLGYTGAILHLINHALAKSALFLTAGTLTQKY  355

Query  358  DSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIA-RSLANERLAWVLGA  416
            +S  IA I G+ +   + G  F   L+ + G PPF +F SEL +A R   +  +  +LG 
Sbjct  356  NSKLIARIQGIGQLLPITGTLFMASLLAIGGAPPFGLFFSELTVATRGFHSAGV--LLGF  413

Query  417  ALLL-IAIGFTALARNSGRMLLG-TPA  441
              L+ IAI F  L    G+M    TP+
Sbjct  414  LFLMVIAIVFAGLVYFGGKMYFSDTPS  440


>gi|238793447|ref|ZP_04637072.1| Hydrogenase-4 component F [Yersinia intermedia ATCC 29909]
 gi|238727220|gb|EEQ18749.1| Hydrogenase-4 component F [Yersinia intermedia ATCC 29909]
Length=543

 Score =  262 bits (670),  Expect = 8e-68, Method: Compositional matrix adjust.
 Identities = 168/428 (40%), Positives = 242/428 (57%), Gaps = 7/428 (1%)

Query  16   SIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVI  75
            S A + T W   T     L     + C VA+G     G        L  D+L+ + L ++
Sbjct  29   SAARMATTWVHFTGITLLLVVALTVVCRVALG-----GEILAAHNWLHIDSLSALFLAIL  83

Query  76   GIVGTLATAASIGYIDTELAHGHID-GRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAI  134
            GI+G +    S+GY+  E+ +G I  G     YG     FL  M+L V +NN+ ++WV I
Sbjct  84   GIIGFITGIYSLGYMRHEVNNGEITVGTLCNYYGFFH-LFLFTMLLVVTSNNLILMWVGI  142

Query  135  EATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALN  194
            EATT+ +AFLVG    R++LEA WKY++IC+VG+A    GTVL+Y  A +  A    A+ 
Sbjct  143  EATTLSSAFLVGLYGQRSSLEAAWKYIIICTVGVAFGLYGTVLVYANAANVLADPGSAIF  202

Query  195  LDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLL  254
              +++EHA  LDP +  LA   +LIG+G K GLFP H+WL DAHS+AP+P SAL+S VLL
Sbjct  203  WTVVSEHAKELDPSLMHLAFVFILIGFGTKTGLFPMHSWLPDAHSEAPSPTSALLSAVLL  262

Query  255  AVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHM  314
              A  V+IR   I+ A  GP + +  LLV G+ ++ V+   +    D+KR+LAYSS+E+M
Sbjct  263  NCALLVIIRYYIIISAAIGPHFPQMLLLVFGMMSVAVSAFFILAQRDMKRLLAYSSVENM  322

Query  315  GLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRL  374
            GLIA+A   G  L + A L H L H + KT+LF   G +   + +  +  I G++R + L
Sbjct  323  GLIAVALGIGGPLGVLAALFHTLNHSLAKTLLFCGSGNVLLKYGTRDMGAIKGIIRVAPL  382

Query  375  IGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNSGR  434
              V  A G + L G+PPF +F SE  +  +  N    W++ A LLL+ +    L R    
Sbjct  383  TAVLLAGGALALAGMPPFNVFISEFMVVAAAINAGHIWLVIALLLLLTLVLAGLVRMIAN  442

Query  435  MLLGTPAA  442
             +LGTP A
Sbjct  443  TVLGTPPA  450


>gi|89074817|ref|ZP_01161271.1| NADH dehydrogenase subunit N [Photobacterium sp. SKA34]
 gi|89049392|gb|EAR54954.1| NADH dehydrogenase subunit N [Photobacterium sp. SKA34]
Length=525

 Score =  261 bits (667),  Expect = 2e-67, Method: Compositional matrix adjust.
 Identities = 174/455 (39%), Positives = 249/455 (55%), Gaps = 31/455 (6%)

Query  2    TGLLLAAILAPLAASIASLITGW-----RR------TTATLTALSATTVLACAVAMGFWM  50
            T LLL+ I APL ASI SL++ +     R+        +T+  L  T+ LA +V      
Sbjct  4    TVLLLSVIAAPLIASIISLLSYFAGSSVRKGAICLHVISTIIVLVGTSTLAWSV-----F  58

Query  51   GSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVL  110
              G    L      D L+ + + V+G+VG +    S+GYI  E   G IDG+   LY  L
Sbjct  59   TQGPLLALDSWFYLDGLSGLFIAVLGVVGFITGLYSLGYIGHEYKEGEIDGKKVSLYYGL  118

Query  111  TPAFLCAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAV  170
               FL  M+++V +NN+ ++WVAIEATTV + FLVG    R++LEA WKY+VICSVG+A 
Sbjct  119  FNLFLATMLISVASNNVIMMWVAIEATTVSSVFLVGLYGKRSSLEAAWKYIVICSVGVAF  178

Query  171  AFLGTVLLYFAARDSGAAAAGALNLDIL----AEHAAGLDPGVARLAGGLLLIGYGAKAG  226
               G++L Y     + AA    ++  +L     E+A  LDP +  L+   ++IG+G K G
Sbjct  179  GLFGSILAY----SNAAAVLSPIDHPVLWTTIKENATLLDPTLVHLSFVFIIIGFGTKTG  234

Query  227  LFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGL  286
            LFP H WL DAHS+AP+PVSAL+S  LL  A  V++R   I     GP + +  L+  G 
Sbjct  235  LFPMHAWLPDAHSEAPSPVSALLSAGLLNCALLVILRYYIITVKAIGPHFPQMLLMTFGF  294

Query  287  ATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVL  346
             ++ VA   +    D+KR+LAYSS+E+MGLI +A   G    IA  LLHV+ H +GKT++
Sbjct  295  LSVAVAAFFIITQRDIKRLLAYSSVENMGLITLAIGLGPIGVIAG-LLHVINHSLGKTLM  353

Query  347  FLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIAR---  403
            F   G +     S  I ++ G+MR + +  V   VG + L G+PPF +F SE  +     
Sbjct  354  FCGAGNILLKFGSRNIDEVKGIMRVAPVTAVLVGVGALALGGVPPFNLFISEFMVVTAGI  413

Query  404  SLANERLAWVLGAALLLIAIGFTALARNSGRMLLG  438
            S  N     +L   LL++ I    LAR     +LG
Sbjct  414  SSGNTMFTIIL---LLMLTIVLAGLARMVASCVLG  445


>gi|258514104|ref|YP_003190326.1| NADH/Ubiquinone/plastoquinone (complex I) [Desulfotomaculum acetoxidans 
DSM 771]
 gi|257777809|gb|ACV61703.1| Hydrogenase 4, membrane subunit [Desulfotomaculum acetoxidans 
DSM 771]
Length=489

 Score =  258 bits (660),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 147/378 (39%), Positives = 225/378 (60%), Gaps = 6/378 (1%)

Query  65   DALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCA  124
            DAL+ V + +IG+VGT+    ++ Y+  +   G ++ R   ++  L   FL +M LAV A
Sbjct  63   DALSSVFVFIIGVVGTICCLYAVSYLRRDQERGELEQRRTGIFFGLLHLFLASMYLAVLA  122

Query  125  NNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARD  184
            +N+GV+WVAIEATT+++A LVG    + +LEA WKY++IC+VGIA A LG +  Y+A R 
Sbjct  123  DNLGVMWVAIEATTIVSALLVGFYGHKESLEAAWKYIIICTVGIAFAMLGIIFTYYAVRG  182

Query  185  SGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAP  244
                   +L+  +L   A  +DP + +LA   +L+GYG KAGLFP HTWL DAHSQAP+P
Sbjct  183  ISGGEEISLSWRLLFSMAGQIDPSLMKLAFIFVLVGYGTKAGLFPLHTWLPDAHSQAPSP  242

Query  245  VSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKR  304
            VSAL+SGVLL  A   +IR   +     G  +    L++ GL +++ ++  + V  D+KR
Sbjct  243  VSALLSGVLLNCAVYAIIRFHLLTVKSVGGNFSAKLLIIFGLLSMVGSLPFILVQKDIKR  302

Query  305  MLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIAD  364
            +LAYSS+EH+G+I +    G  L     LLH++ H +GK+VLFL+ G L   ++S  I  
Sbjct  303  LLAYSSVEHIGIIVLGVGIGGVLGYTGALLHLINHALGKSVLFLSAGTLTQKYNSKLIPK  362

Query  365  ITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIAR---SLANERLAWVLGAALLLI  421
            + G+ +   +    F   L+ + G PPF +F SEL +A    +   + + ++    L++I
Sbjct  363  MKGIGQLLPITSTVFMASLLAIGGAPPFGLFISELNVASGGFAYVGKSVGFIF---LMVI  419

Query  422  AIGFTALARNSGRMLLGT  439
            AI F  L   +G+M    
Sbjct  420  AIVFAGLIYFAGKMYFSN  437


>gi|341955809|gb|EGT82259.1| hydrogenase-4 component F [Haemophilus haemolyticus M19107]
Length=512

 Score =  258 bits (660),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 136/328 (42%), Positives = 207/328 (64%), Gaps = 0/328 (0%)

Query  65   DALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCA  124
            D+L+ + L +I +VG+LA   SIGY++TEL   HID ++   Y      F   M+++V  
Sbjct  70   DSLSAIFLGLIAVVGSLAGVYSIGYMNTELEEWHIDFKTYAHYHGFLHLFFFTMIVSVIT  129

Query  125  NNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARD  184
            NN+ ++WVAIEATT+ +AFLVG  + +T+LEA WKY++ICSVG+A    GT+L +  A  
Sbjct  130  NNLILMWVAIEATTLSSAFLVGTYKQKTSLEAAWKYIIICSVGVAFGLYGTLLTFANANG  189

Query  185  SGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAP  244
              A  + A+    + + A GL+P +  +A   +LIG+G K GLFP HTWL+DAHS+AP+P
Sbjct  190  VLADPSQAIFWSAVNQQATGLNPMLMYIAFAFVLIGFGTKCGLFPMHTWLSDAHSEAPSP  249

Query  245  VSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKR  304
            VSA++S VLL  A  V++R   ++    G  + +  +L+ GL ++LVA L + V  D+KR
Sbjct  250  VSAILSAVLLNCAMLVVLRYYTLVSKAVGAEFPQTLMLIFGLLSVLVAALFIIVQFDIKR  309

Query  305  MLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIAD  364
            +LAYSS+E+MGLI+ A   G  + + A LLH + H + KT+LF A G +   + +  +  
Sbjct  310  LLAYSSIENMGLISFAFGLGGPIGVFAGLLHTINHSLAKTLLFCASGNILLKYKTRDMNQ  369

Query  365  ITGVMRRSRLIGVSFAVGLIVLLGLPPF  392
            + G+ R + +  V FA G + L  +PPF
Sbjct  370  VRGLWRVAPVSAVLFAGGALALGSIPPF  397


>gi|90426042|ref|YP_534412.1| hydrogenase 4 subunit F [Rhodopseudomonas palustris BisB18]
 gi|90108056|gb|ABD90093.1| NADH dehydrogenase (quinone) [Rhodopseudomonas palustris BisB18]
Length=512

 Score =  258 bits (659),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 150/377 (40%), Positives = 212/377 (57%), Gaps = 1/377 (0%)

Query  25   RRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATA  84
            RR      A     ++   + +G  + SG     G  L  D L  + + +IG+VG L   
Sbjct  32   RRIELLHLASLVVVLVLALMTVGHVLSSGNLMAFGDWLMVDPLAAIFVGLIGVVGCLTGF  91

Query  85   ASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAIEATTVITAFL  144
             SIGYI  ++AHG +     +LY      FL  M+L V ANNI ++WV IEATT+ +AFL
Sbjct  92   YSIGYIRHDVAHGELTPWKQKLYYGFFNLFLFTMLLVVTANNIVMMWVGIEATTLGSAFL  151

Query  145  VGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAG  204
            VG     T+LEA WKY++ICSVG+A    GTVL +  A  S       L   I+A HA  
Sbjct  152  VGIYGKGTSLEAAWKYLIICSVGVAFGLYGTVLTFANAAASIDPHQAVLWTSIMA-HAQE  210

Query  205  LDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRL  264
            LDP + ++A   +LIG+G KAG+FP H WL DAHS+AP+PVS L+SGVLL     V+IR 
Sbjct  211  LDPTLIKIAFVFVLIGFGTKAGIFPMHAWLPDAHSEAPSPVSGLLSGVLLKCGLFVIIRY  270

Query  265  RPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAG  324
              +     GP + ++ LLV+G+ T+ ++  ++ V  D KR LAY S+EH+GLI I    G
Sbjct  271  YAVTIKAIGPEFPQSMLLVLGVLTVAISAFLVFVQHDFKRKLAYHSIEHVGLIVIGLGVG  330

Query  325  TTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLI  384
              L IAA LLH + H   K +LF   G +   + +  +  + G++R + + G+    G +
Sbjct  331  GPLGIAAALLHTINHSFTKALLFCGSGNVLQKYGTRDLRSVKGILRTAPVTGLFIMAGAL  390

Query  385  VLLGLPPFAMFASELAI  401
             L G PPF +F SE  +
Sbjct  391  ALAGFPPFNVFVSEFMV  407


>gi|94313590|ref|YP_586799.1| hydrogenase 4 subunit F [Cupriavidus metallidurans CH34]
 gi|93357442|gb|ABF11530.1| hydrogenase 4 subunit F [Cupriavidus metallidurans CH34]
Length=484

 Score =  258 bits (658),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 163/418 (39%), Positives = 225/418 (54%), Gaps = 28/418 (6%)

Query  65   DALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCA  124
            D+L V ++ +  +VG   +  S  Y+  E  HG +     RLY  +   F+  M+LA+  
Sbjct  65   DSLNVFLVALTALVGLTTSLFSRPYMRIERDHGKMTPPRLRLYHSMYQLFMFTMLLALTT  124

Query  125  NNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARD  184
            NN+G++WVA+EA T+ T  LV   RT  +LEA WKY ++C VGIA A  GTVLLY AA  
Sbjct  125  NNLGIVWVAMEAATLTTVLLVSVYRTAASLEAAWKYFILCGVGIAQALFGTVLLYMAAEK  184

Query  185  SGAAAAGAL---NLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQA  241
               A  GAL   NL+ + EH   LDP +  LA   L IGYG K GL P H WL DAH++ 
Sbjct  185  VVGAEGGALLWTNLNAVKEH---LDPNIITLAFAFLFIGYGTKVGLVPLHNWLPDAHAEG  241

Query  242  PAPVSALMSGVLLAVAFSVLIRLRPILDAVSGP---AYLRNGLLVVGLATLLVAVLMLTV  298
            P PVSA++SG+LL VA   ++R + + DA  G     YL  G    GL +++ AV  L  
Sbjct  242  PTPVSAVLSGLLLNVALYAVLRCKMLTDAAVGSHLTGYLMMGF---GLLSVVAAVFFLMR  298

Query  299  TGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHD  358
              DVKRM AYSS+EHMGLI  A   G  +A  A LLH+  H + K+ +F A G       
Sbjct  299  QRDVKRMFAYSSIEHMGLITFAFGMGGPIASYAGLLHMTMHSLVKSAIFFAVGHAAQKAG  358

Query  359  STAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAAL  418
            +  + DI G++R S  +G    +G + +LG+PPF +FASE  I  +   E  AW     L
Sbjct  359  TQIMDDIRGLIRVSPTVGWGLMLGALAILGMPPFGVFASEFLIVTTAMREH-AWATPFLL  417

Query  419  LLIAIGFTALARNSGRMLLG----TPAAGAPAITVPATAAAALMVGIVVSAALGITAG  472
            + + + F ++      M+ G     P A  PA           +V + +  ALG+ AG
Sbjct  418  IALGVAFASIFSRVQPMVFGDTELKPLAHPPA-----------LVPVFLHLALGLVAG  464


>gi|238788861|ref|ZP_04632652.1| Hydrogenase-4 component F [Yersinia frederiksenii ATCC 33641]
 gi|238723166|gb|EEQ14815.1| Hydrogenase-4 component F [Yersinia frederiksenii ATCC 33641]
Length=545

 Score =  256 bits (655),  Expect = 5e-66, Method: Compositional matrix adjust.
 Identities = 153/386 (40%), Positives = 223/386 (58%), Gaps = 5/386 (1%)

Query  16   SIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVI  75
            S A + T W   T     L     + C VA+G     G        L  D+L+ + L ++
Sbjct  29   SSARMATTWVHFTGITLLLVVALTVVCRVALG-----GEILVAHNWLHIDSLSALFLAIL  83

Query  76   GIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAIE  135
            G++G +    S+GY+  E+ +G I   +   Y      FL  M+L V +NN+ ++WV IE
Sbjct  84   GVIGFITGLYSLGYMRHEVNNGEITVSTLCSYYGFFHLFLFTMLLVVTSNNLILMWVGIE  143

Query  136  ATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNL  195
            ATT+ +AFLVG    R++LEA WKY++IC+VG+A    GTVL+Y  A +  A  + A+  
Sbjct  144  ATTLSSAFLVGLYGQRSSLEAAWKYIIICTVGVAFGLYGTVLVYANAANVLADPSSAIFW  203

Query  196  DILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLA  255
             ++AEHA  LDP +  LA   +LIG+G K GLFP H+WL DAHS+AP+P SAL+S VLL 
Sbjct  204  TVVAEHAKELDPSLMHLAFVFILIGFGTKTGLFPMHSWLPDAHSEAPSPTSALLSAVLLN  263

Query  256  VAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMG  315
             A  V+IR   I+ A  GP + +  LLV G+ ++ V+   +    D+KR+LAYSS+E+MG
Sbjct  264  CALLVIIRYYIIISAAIGPHFPQMLLLVFGMMSVAVSAFFILAQRDMKRLLAYSSVENMG  323

Query  316  LIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLI  375
            LIA+A   G  L + A L H L H + KT+LF   G +   + +  +  I G++R + L 
Sbjct  324  LIAVALGIGGPLGVLAALFHTLNHSLAKTLLFCGSGNVLLKYGTRDMGAIKGIIRVAPLT  383

Query  376  GVSFAVGLIVLLGLPPFAMFASELAI  401
             V  A G + L G+PPF +F SE  +
Sbjct  384  AVLLAGGALALAGMPPFNVFISEFMV  409


>gi|238784031|ref|ZP_04628046.1| Hydrogenase-4 component F [Yersinia bercovieri ATCC 43970]
 gi|238715008|gb|EEQ07005.1| Hydrogenase-4 component F [Yersinia bercovieri ATCC 43970]
Length=545

 Score =  256 bits (653),  Expect = 9e-66, Method: Compositional matrix adjust.
 Identities = 151/359 (43%), Positives = 215/359 (60%), Gaps = 7/359 (1%)

Query  42   CAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHID-  100
            C VA+G     G        L  D+L+ + L ++GI+G +    S+GY+  E+ +G I  
Sbjct  55   CRVALG-----GEILAAHHWLHIDSLSALFLAILGIIGFITGLYSLGYMRHEVNNGEITV  109

Query  101  GRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKY  160
            G     YG     FL  M+L V +NN+ ++WV IEATT+ +AFLVG    R++LEA WKY
Sbjct  110  GTLCNYYGFFH-LFLFTMLLVVTSNNLILMWVGIEATTLSSAFLVGLYGQRSSLEAAWKY  168

Query  161  VVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIG  220
            ++IC+VG+A    GTVL+Y  A    A    A+   ++AEHA  LDP +  LA   +LIG
Sbjct  169  IIICTVGVAFGLYGTVLVYANAASVLADPGSAIFWTVVAEHAKELDPRLMHLAFVFILIG  228

Query  221  YGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNG  280
            +G K GLFP H+WL DAHS+AP+P SAL+S VLL  A  V+IR   I+ A  GP + +  
Sbjct  229  FGTKTGLFPMHSWLPDAHSEAPSPTSALLSAVLLNCALLVIIRYYIIISAAIGPHFPQML  288

Query  281  LLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHG  340
            LLV G+ ++ V+ L +    D+KR+LAYSS+E+MGLIA+A   G  L + A L H L H 
Sbjct  289  LLVFGMMSVAVSALFILAQRDMKRLLAYSSVENMGLIAVALGIGGPLGVVAALFHTLNHS  348

Query  341  IGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASEL  399
            + KT+LF   G +   + +  +  I G++R + L  V  A G + L G+PPF++F SE 
Sbjct  349  LAKTLLFCGSGNVLLKYGTRDMGAIKGIIRVAPLTAVLLAGGALALAGMPPFSLFISEF  407


>gi|139437058|ref|ZP_01771218.1| Hypothetical protein COLAER_00193 [Collinsella aerofaciens ATCC 
25986]
 gi|133776705|gb|EBA40525.1| Hypothetical protein COLAER_00193 [Collinsella aerofaciens ATCC 
25986]
Length=521

 Score =  255 bits (651),  Expect = 1e-65, Method: Compositional matrix adjust.
 Identities = 163/451 (37%), Positives = 245/451 (55%), Gaps = 16/451 (3%)

Query  33   ALSATTVLACAVAMGFWMGSGAQFG-LGGLLRADALTVVMLVVIGIVGTLATAASIGYID  91
            +++AT VL+   A G  + SG     LG  L  D+L+ + ++++GI+G +    SI YI 
Sbjct  40   SVAATLVLSVVTA-GTMLSSGQNIDALGLWLHLDSLSSIFVLLVGIIGFITGVYSISYIK  98

Query  92   TELAHGHIDGRSARLYGVLTPAFLCAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTR  151
             ++    +     + Y  L   F+  M+LA  +NNI + W A+EATT+ T FLVG  + +
Sbjct  99   IDIKEKTMPAERTKQYYALFSLFVFTMLLACLSNNIILTWAAVEATTLSTVFLVGIYKNK  158

Query  152  TALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVAR  211
             ALEA+WKY ++C+ G+A    GT+L+Y  A D    A  A  L  +  +A   DP + R
Sbjct  159  QALEASWKYAMVCTAGVAFGLFGTLLIYANAADIMPNAHEAAFLTSIMPYADQFDPMLVR  218

Query  212  LAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAV  271
            LA   ++IG+G KAGLFP HTWL DAHSQAP+PVSAL+SGVLL  A  V+IR   +    
Sbjct  219  LAFAFIVIGFGTKAGLFPMHTWLPDAHSQAPSPVSALLSGVLLKCAMLVIIRFYSLSIIT  278

Query  272  SGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAA  331
             G  Y R  LL++G  ++LVA L +    D+KR  AYSS++++G++A+    G  L IAA
Sbjct  279  VGDTYPRTLLLILGTLSILVAALCIFKQDDIKRRFAYSSVDNVGVVALCLGIGGPLGIAA  338

Query  332  LLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPP  391
             LLH + HG  K + F   G +Q  + +  +  I GV+  + +      + L+ L   PP
Sbjct  339  CLLHCIFHGFTKALAFCMAGNIQHIYHTRDLNKIKGVVEIAPVTAALTIIALLALAAFPP  398

Query  392  FAMFASELAIARSLANERLAWVLGAALLLIAIGFT---------ALARNSGRMLLGTPAA  442
            FA+F SE     +       WV    ++L+AIG T         AL    G+   G    
Sbjct  399  FALFISEFLTFVAGIQSGPIWV----VVLVAIGLTGVYFALTGIALKSIFGKAPEGMKRH  454

Query  443  GAPAI-TVPATAAAALMVGIVVSAALGITAG  472
              PA+  +P  A A +++   ++  + IT+G
Sbjct  455  EVPALMIIPEIALAIVVMWFGIATPVAITSG  485



Lambda     K      H
   0.326    0.138    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1041221813024




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40