BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0089
Length=197
Score E
Sequences producing significant alignments: (Bits) Value
gi|15607231|ref|NP_214603.1| methyltransferase/methylase [Mycoba... 395 1e-108
gi|340625126|ref|YP_004743578.1| putative methyltransferase/meth... 379 1e-103
gi|183980277|ref|YP_001848568.1| methyltransferase/methylase [My... 285 2e-75
gi|118619908|ref|YP_908240.1| methyltransferase/methylase [Mycob... 268 2e-70
gi|284034454|ref|YP_003384385.1| type 11 methyltransferase [Krib... 137 6e-31
gi|271966531|ref|YP_003340727.1| ubiquinone/menaquinone biosynth... 136 2e-30
gi|345009769|ref|YP_004812123.1| type 11 methyltransferase [Stre... 135 4e-30
gi|302541681|ref|ZP_07294023.1| putative methyltransferase [Stre... 133 2e-29
gi|269795274|ref|YP_003314729.1| ubiquinone/menaquinone biosynth... 132 2e-29
gi|54024875|ref|YP_119117.1| hypothetical protein nfa29060 [Noca... 120 9e-26
gi|332670728|ref|YP_004453736.1| type 11 methyltransferase [Cell... 108 4e-22
gi|336326054|ref|YP_004606020.1| hypothetical protein CRES_1502 ... 107 8e-22
gi|317509021|ref|ZP_07966652.1| methyltransferase domain-contain... 105 4e-21
gi|312197279|ref|YP_004017340.1| methyltransferase type 12 [Fran... 100 1e-19
gi|169628387|ref|YP_001702036.1| hypothetical protein MAB_1294c ... 100 1e-19
gi|111223050|ref|YP_713844.1| putative methyltransferase [Franki... 96.3 2e-18
gi|297196954|ref|ZP_06914351.1| methyltransferase type 12 [Strep... 95.1 5e-18
gi|340359826|ref|ZP_08682299.1| type 12 methyltransferase [Actin... 94.0 1e-17
gi|118467757|ref|YP_888968.1| methyltransferase [Mycobacterium s... 91.3 8e-17
gi|302528805|ref|ZP_07281147.1| methyltransferase type 12 [Strep... 88.2 5e-16
gi|120405036|ref|YP_954865.1| type 12 methyltransferase [Mycobac... 87.4 1e-15
gi|337769482|emb|CCB78195.1| SAM-dependent methyltransferase [St... 87.0 1e-15
gi|240170947|ref|ZP_04749606.1| putative methyltransferase [Myco... 86.3 2e-15
gi|311900519|dbj|BAJ32927.1| hypothetical protein KSE_71710 [Kit... 85.9 3e-15
gi|302528929|ref|ZP_07281271.1| predicted protein [Streptomyces ... 84.7 7e-15
gi|152966704|ref|YP_001362488.1| type 12 methyltransferase [Kine... 84.7 7e-15
gi|134100186|ref|YP_001105847.1| hypothetical protein SACE_3648 ... 83.2 2e-14
gi|297625401|ref|YP_003687164.1| methyltransferase [Propionibact... 82.0 4e-14
gi|254777576|ref|ZP_05219092.1| methyltransferase type 12 [Mycob... 81.3 8e-14
gi|333022936|ref|ZP_08451000.1| putative methyltransferase [Stre... 81.3 8e-14
gi|318059073|ref|ZP_07977796.1| putative methyltransferase [Stre... 79.7 2e-13
gi|23008602|ref|ZP_00049980.1| COG0500: SAM-dependent methyltran... 79.7 2e-13
gi|326202811|ref|ZP_08192678.1| Methyltransferase type 11 [Clost... 79.7 2e-13
gi|336117301|ref|YP_004572068.1| hypothetical protein MLP_16510 ... 79.3 3e-13
gi|342859512|ref|ZP_08716166.1| type 12 methyltransferase [Mycob... 78.6 4e-13
gi|256824037|ref|YP_003147997.1| ubiquinone/menaquinone biosynth... 78.2 6e-13
gi|300788556|ref|YP_003768847.1| methyltransferase [Amycolatopsi... 77.8 7e-13
gi|295835362|ref|ZP_06822295.1| methyltransferase [Streptomyces ... 77.8 7e-13
gi|256393722|ref|YP_003115286.1| methyltransferase type 11 [Cate... 77.4 1e-12
gi|91199610|emb|CAI77964.1| putative SAM-dependent methyltransfe... 76.6 2e-12
gi|257068133|ref|YP_003154388.1| ubiquinone/menaquinone biosynth... 76.3 2e-12
gi|257055280|ref|YP_003133112.1| methyltransferase family protei... 76.3 2e-12
gi|302387451|ref|YP_003823273.1| Methyltransferase type 11 [Clos... 74.3 9e-12
gi|326776861|ref|ZP_08236126.1| Methyltransferase type 11 [Strep... 74.3 1e-11
gi|182436232|ref|YP_001823951.1| putative methyltransferase [Str... 72.8 2e-11
gi|302335032|ref|YP_003800239.1| Methyltransferase type 11 [Olse... 72.4 3e-11
gi|311404573|gb|ADP94233.1| TunM [Streptomyces chartreusis NRRL ... 72.0 5e-11
gi|296139222|ref|YP_003646465.1| type 12 methyltransferase [Tsuk... 70.5 1e-10
gi|254820551|ref|ZP_05225552.1| putative methyltransferase [Myco... 70.5 1e-10
gi|302549463|ref|ZP_07301805.1| methyltransferase type 12 [Strep... 70.5 1e-10
>gi|15607231|ref|NP_214603.1| methyltransferase/methylase [Mycobacterium tuberculosis H37Rv]
gi|15839469|ref|NP_334506.1| methyltransferase, putative [Mycobacterium tuberculosis CDC1551]
gi|31791267|ref|NP_853760.1| methyltransferase/methylase [Mycobacterium bovis AF2122/97]
80 more sequence titles
Length=197
Score = 395 bits (1016), Expect = 1e-108, Method: Compositional matrix adjust.
Identities = 196/197 (99%), Positives = 197/197 (100%), Gaps = 0/197 (0%)
Query 1 VDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA 60
+DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA
Sbjct 1 MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA 60
Query 61 QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV
Sbjct 61 QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
Query 121 VTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGAC 180
VTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGAC
Sbjct 121 VTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGAC 180
Query 181 IRRLLYGRVLVTWRAPV 197
IRRLLYGRVLVTWRAPV
Sbjct 181 IRRLLYGRVLVTWRAPV 197
>gi|340625126|ref|YP_004743578.1| putative methyltransferase/methylase [Mycobacterium canettii
CIPT 140010059]
gi|340003316|emb|CCC42434.1| putative methyltransferase/methylase [Mycobacterium canettii
CIPT 140010059]
Length=198
Score = 379 bits (973), Expect = 1e-103, Method: Compositional matrix adjust.
Identities = 189/196 (97%), Positives = 191/196 (98%), Gaps = 0/196 (0%)
Query 2 DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQ 61
DQPWNANIHYDALLDAMV G QCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVL+RAQ
Sbjct 3 DQPWNANIHYDALLDAMVRPGAQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLQRAQ 62
Query 62 TRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
TRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV
Sbjct 63 TRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 122
Query 122 TFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACI 181
TFV PSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTL+ELRSHVRALLPGA I
Sbjct 123 TFVKPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLYELRSHVRALLPGARI 182
Query 182 RRLLYGRVLVTWRAPV 197
RRLLYGRVLVTWRAPV
Sbjct 183 RRLLYGRVLVTWRAPV 198
>gi|183980277|ref|YP_001848568.1| methyltransferase/methylase [Mycobacterium marinum M]
gi|183173603|gb|ACC38713.1| methyltransferase/methylase [Mycobacterium marinum M]
Length=199
Score = 285 bits (730), Expect = 2e-75, Method: Compositional matrix adjust.
Identities = 139/194 (72%), Positives = 160/194 (83%), Gaps = 0/194 (0%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
QPWN NIHYDALL A V GTQ LDVGCGDG L+ARLA R+P VTA+D+DA VLRRA+
Sbjct 5 QPWNINIHYDALLAATVAPGTQTALDVGCGDGFLSARLADRVPDVTALDVDADVLRRAER 64
Query 63 RFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVT 122
RFA+ IRW+H D+MT ELP+ GFDAV++NA+LHHIEDTR AL RL LV P GTLAVVT
Sbjct 65 RFADTSIRWVHGDVMTGELPHRGFDAVLANASLHHIEDTRGALIRLAELVLPAGTLAVVT 124
Query 123 FVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIR 182
FV PSLRNGLWHLT+W+A G+ANRV+ KWEH+A IKWPPP T +LR VR LLPGA +R
Sbjct 125 FVRPSLRNGLWHLTAWLATGVANRVRRKWEHTAAIKWPPPVTFSQLRELVRELLPGARVR 184
Query 183 RLLYGRVLVTWRAP 196
RLLYGRVL+TW+AP
Sbjct 185 RLLYGRVLITWQAP 198
>gi|118619908|ref|YP_908240.1| methyltransferase/methylase [Mycobacterium ulcerans Agy99]
gi|118572018|gb|ABL06769.1| methyltransferase/methylase [Mycobacterium ulcerans Agy99]
Length=199
Score = 268 bits (686), Expect = 2e-70, Method: Compositional matrix adjust.
Identities = 133/194 (69%), Positives = 156/194 (81%), Gaps = 0/194 (0%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
QPWN NIHYDALL A V GTQ LDVGCGDG L+ARL R+P VTA+D+DA VLRRA+
Sbjct 5 QPWNINIHYDALLAATVAPGTQTALDVGCGDGFLSARLVDRVPDVTALDVDADVLRRAEH 64
Query 63 RFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVT 122
RFA+ I W+H D+MT ELP+ GFDAV+++A+LHHIE TR AL RL LV PGGTLAVVT
Sbjct 65 RFADTSIWWVHGDVMTGELPHRGFDAVLASASLHHIEGTRGALIRLAELVLPGGTLAVVT 124
Query 123 FVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIR 182
FV PS RN LWHLT+W+A G+ANRV+ KW+H+A IKWPPP T +LR VR LLPGA +R
Sbjct 125 FVRPSPRNVLWHLTAWLATGVANRVRRKWDHTAAIKWPPPVTFSQLRELVRELLPGARVR 184
Query 183 RLLYGRVLVTWRAP 196
RLLYGRVL+TW+AP
Sbjct 185 RLLYGRVLITWQAP 198
>gi|284034454|ref|YP_003384385.1| type 11 methyltransferase [Kribbella flavida DSM 17836]
gi|283813747|gb|ADB35586.1| Methyltransferase type 11 [Kribbella flavida DSM 17836]
Length=214
Score = 137 bits (346), Expect = 6e-31, Method: Compositional matrix adjust.
Identities = 85/197 (44%), Positives = 109/197 (56%), Gaps = 11/197 (5%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N HY L+ A +P + LDVG GDGLLA L R+P V A+D DA VL RA R
Sbjct 9 WNHNTHYHRLVLAALPANARSALDVGTGDGLLATDLRERVPEVVAIDPDAAVLERA--RA 66
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV--- 121
+ A ++WLH D+MT LP A FD V + A +HH+ D LSR L PGG++ VV
Sbjct 67 SEADVQWLHGDVMTQSLPLAHFDLVGTIATVHHLPDLADGLSRFAELTAPGGSVVVVGCA 126
Query 122 --TFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGA 179
+ V+ L G+ L V +R +G W+HSAP++ P T E+RS A LPG
Sbjct 127 RASTVSDYLVEGVGILQHQV----LSRTRGYWQHSAPVEMRFPHTYSEVRSIATATLPGV 182
Query 180 CIRRLLYGRVLVTWRAP 196
RRL R L+ W P
Sbjct 183 RWRRLPLFRYLLHWTRP 199
>gi|271966531|ref|YP_003340727.1| ubiquinone/menaquinone biosynthesis methylase-like protein [Streptosporangium
roseum DSM 43021]
gi|270509706|gb|ACZ87984.1| Methylase involved in ubiquinone/menaquinone biosynthesis-like
protein [Streptosporangium roseum DSM 43021]
Length=200
Score = 136 bits (342), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 79/193 (41%), Positives = 108/193 (56%), Gaps = 4/193 (2%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN NIHY + VP G Q LDVGCG+G+LA L + +P+VT +D+DAP + Q R
Sbjct 9 WNHNIHYHPRILRAVPDGAQRALDVGCGEGMLARGLRQAVPHVTGIDLDAPSI--GQARE 66
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
+ ++ D +T A FD V S A LHH+ D L+R+ L+ PGG LAVV
Sbjct 67 HPDDVDYILGDFLTHPFTPASFDVVASVATLHHM-DAAAGLARMRELLRPGGVLAVVGLA 125
Query 125 TPSLRNGLWHLTSWVACGMANR-VKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRR 183
++ N L + V G +R +KG WEH +P WPPP T ++R+ +LPG+ RR
Sbjct 126 RSTMPNDLPRDLAGVVVGALHRAMKGHWEHPSPTVWPPPVTYPQMRALAAEILPGSRYRR 185
Query 184 LLYGRVLVTWRAP 196
L R +TWR P
Sbjct 186 HLLWRYSITWRRP 198
>gi|345009769|ref|YP_004812123.1| type 11 methyltransferase [Streptomyces violaceusniger Tu 4113]
gi|344036118|gb|AEM81843.1| Methyltransferase type 11 [Streptomyces violaceusniger Tu 4113]
Length=200
Score = 135 bits (339), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 79/193 (41%), Positives = 108/193 (56%), Gaps = 4/193 (2%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN IHY + VP G Q LDVGCG+G+LA L + +P+VT +D+DA + R
Sbjct 9 WNNTIHYHPRILGAVPDGAQRALDVGCGEGMLARELRQAVPHVTGIDLDAAGIDLG--RA 66
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
+ ++ D ++ A FD + S AALHH+ D T L+R+ L+ PGG LAVV
Sbjct 67 YRDDVDYILGDFVSHPFEPASFDVIASVAALHHM-DGATGLARMRDLLRPGGVLAVVGLA 125
Query 125 TPSLRNGLWHLTSWVACGMANR-VKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRR 183
+L L H+ + VA G +R VKG W H +PI WPPP T E+R+ +LPG+ RR
Sbjct 126 RNTLPKDLPHILAGVAVGAVHRAVKGLWHHPSPIVWPPPVTYPEMRAMAAEILPGSQHRR 185
Query 184 LLYGRVLVTWRAP 196
L R + WR P
Sbjct 186 HLLWRYSIIWRKP 198
>gi|302541681|ref|ZP_07294023.1| putative methyltransferase [Streptomyces hygroscopicus ATCC 53653]
gi|302459299|gb|EFL22392.1| putative methyltransferase [Streptomyces himastatinicus ATCC
53653]
Length=198
Score = 133 bits (334), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 78/193 (41%), Positives = 110/193 (57%), Gaps = 5/193 (2%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN NIHY + VP G + LDVGCG+G+LA L R +P+VT +D+ P + Q R
Sbjct 9 WNHNIHYHHRILRAVPDGARHALDVGCGEGMLARELRRTVPHVTGIDLHEPSI--DQARA 66
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
I ++ D +T A F+ + S A LHH+ D T L+R+ L+ PGG LAVV
Sbjct 67 HPGDIDYVLGDFLTHPFEPASFEVIASVATLHHM-DAATGLARMRDLLRPGGVLAVVGLA 125
Query 125 TPSLRNGLWHLTSWVACGMANR-VKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRR 183
+ R+ L ++ + VA G A+R VKG+W+H +PI WPPP T ++R+ +LPGA RR
Sbjct 126 RNTPRD-LPYVLAGVAVGTAHRAVKGQWQHPSPIVWPPPVTYRQMRALAAEVLPGARYRR 184
Query 184 LLYGRVLVTWRAP 196
R + W P
Sbjct 185 HALFRYSLVWHKP 197
>gi|269795274|ref|YP_003314729.1| ubiquinone/menaquinone biosynthesis methylase [Sanguibacter keddieii
DSM 10542]
gi|269097459|gb|ACZ21895.1| methylase involved in ubiquinone/menaquinone biosynthesis [Sanguibacter
keddieii DSM 10542]
Length=200
Score = 132 bits (333), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 80/193 (42%), Positives = 103/193 (54%), Gaps = 4/193 (2%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN NIHY + +VP G Q LDVG GDGLLA+ L R+P+VT +D+DA L A+ R
Sbjct 9 WNHNIHYHRRILDVVPAGAQTALDVGAGDGLLASELRERVPHVTGLDLDATALESARRR- 67
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
+ + W+ D MT LP FD V S A LHH+ AL RL L TPGG +AVV
Sbjct 68 -DPDVTWVQGDAMTVPLPTGSFDVVASIATLHHLPGLDEALQRLVDLTTPGGVVAVVGLA 126
Query 125 TPSL-RNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRR 183
S + ++ + + R G WEHSAP PPP T ++R +LPGA +R
Sbjct 127 QNSRPLDYVYEVVGLLQHRRLARRHGHWEHSAPTA-PPPHTYADVRRSAARVLPGARWQR 185
Query 184 LLYGRVLVTWRAP 196
L R + W P
Sbjct 186 LALWRYSLVWTKP 198
>gi|54024875|ref|YP_119117.1| hypothetical protein nfa29060 [Nocardia farcinica IFM 10152]
gi|54016383|dbj|BAD57753.1| hypothetical protein [Nocardia farcinica IFM 10152]
Length=205
Score = 120 bits (302), Expect = 9e-26, Method: Compositional matrix adjust.
Identities = 80/195 (42%), Positives = 107/195 (55%), Gaps = 5/195 (2%)
Query 5 WNANIHY-DALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTR 63
WN NIHY D L++A+ P + +LDVGCG+G+L RL R + +D A + A+ +
Sbjct 11 WNTNIHYHDVLVEAVAPHAGR-ILDVGCGEGMLCRRLRRDDRAIVGIDTHAESIALARAQ 69
Query 64 FANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF 123
+L AD++T A FDA+VS A LHH+ D AL+ + L+ PGGTLA+V
Sbjct 70 SGADGPDYLCADVLTHPFEPASFDAIVSVATLHHL-DPDAALTTMARLLKPGGTLAIVGL 128
Query 124 VTPSLRNGLWHLTSWVACGMANRVKG--KWEHSAPIKWPPPQTLHELRSHVRALLPGACI 181
P + L V +R+ G WEH +PI WPPP T E+R RALLPG
Sbjct 129 ARPRWPHDLPVEALAVLAFTYHRLAGHRHWEHPSPIVWPPPHTYAEIRDTARALLPGVRY 188
Query 182 RRLLYGRVLVTWRAP 196
RR LY R + WR P
Sbjct 189 RRHLYWRYSLRWRKP 203
>gi|332670728|ref|YP_004453736.1| type 11 methyltransferase [Cellulomonas fimi ATCC 484]
gi|332339766|gb|AEE46349.1| Methyltransferase type 11 [Cellulomonas fimi ATCC 484]
Length=196
Score = 108 bits (270), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 80/200 (40%), Positives = 107/200 (54%), Gaps = 12/200 (6%)
Query 2 DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARL-ARRIPYVTAVDIDAPVLRRA 60
++ WN N HY L P G + LDVGCG+GLL RL A +P VT VD DA + RA
Sbjct 3 EERWNHNTHYHRLALRHAP-GARTALDVGCGEGLLTRRLRAAGVPSVTGVDADADQVARA 61
Query 61 QTRFANAPIRWLHADIMTAELPNAG-FDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLA 119
+ + + +L D + ++P+ G FD V A LHH+ D R L RL L PGG L
Sbjct 62 RAHADSDGLHYLLGDAL--DVPHDGRFDLVTCVATLHHL-DLRAGLRRLASLTAPGGHLV 118
Query 120 VVTFV---TPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALL 176
VV TP+ + L + + + +R +G WEH +P+ P + E+R RALL
Sbjct 119 VVGLAAVRTPA--DALLSVAAVPVAAVVDRARGTWEHGSPVT-DPREAYGEVRDTARALL 175
Query 177 PGACIRRLLYGRVLVTWRAP 196
PG RR LY R +TWRAP
Sbjct 176 PGVRWRRHLYWRYSLTWRAP 195
>gi|336326054|ref|YP_004606020.1| hypothetical protein CRES_1502 [Corynebacterium resistens DSM
45100]
gi|336102036|gb|AEI09856.1| hypothetical protein CRES_1502 [Corynebacterium resistens DSM
45100]
Length=199
Score = 107 bits (267), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 62/194 (32%), Positives = 96/194 (50%), Gaps = 3/194 (1%)
Query 1 VDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA 60
+ WN N HY L+ LDVGCG+GLLA L+ R V +D + VL A
Sbjct 5 IQHGWNHNRHYHNLILEQCQPTMNSALDVGCGEGLLAQVLSARGLTVKGIDANDDVLVTA 64
Query 61 QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
+ R ++W+ D++T + F+ V + A +HH + AL+RL LV+PGGTL +
Sbjct 65 RRR--ECGVKWVQGDVLTHDFGERQFNFVTAVATVHHFPEFEAALARLRSLVSPGGTLVI 122
Query 121 VTFVTPSLR-NGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGA 179
+ + + ++ + V +++ E SAP K+ P T ++R+ RA PG
Sbjct 123 LGLAKSTTTVDFVYDVIGAVQHQFYTKLRDYVEDSAPKKFEFPLTYQQVRTQARACFPGC 182
Query 180 CIRRLLYGRVLVTW 193
RRL R L+ W
Sbjct 183 SFRRLPLFRYLLVW 196
>gi|317509021|ref|ZP_07966652.1| methyltransferase domain-containing protein [Segniliparus rugosus
ATCC BAA-974]
gi|316252676|gb|EFV12115.1| methyltransferase domain-containing protein [Segniliparus rugosus
ATCC BAA-974]
Length=199
Score = 105 bits (262), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 71/201 (36%), Positives = 102/201 (51%), Gaps = 7/201 (3%)
Query 1 VDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIP--YVTAVDIDAPVLR 58
+ + WN NIHY L+ VP + VLDVGCG G L + + P + VD+ LR
Sbjct 1 MTERWNTNIHYQRLMVRAVPETARRVLDVGCGVGTLVPEVRAKAPGALIVGVDLHEESLR 60
Query 59 RAQTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTL 118
A+ + ++ AD++ A L + FDA++S+A HH+ AL R+ L+ PGG L
Sbjct 61 IARAEHPGPDLAFVRADVLAAPLRDESFDAILSSATAHHL-PLEAALRRMAALLRPGGRL 119
Query 119 AVVTFVTPSLRNG-LWHLTSWVACGMANRVKG--KWEHSAPIKWPPPQTLHELRSHVRAL 175
VV L LW L VA +G KWEH +P+ P + ++ + V+ +
Sbjct 120 VVVALTRERLPAALLWGLVGAVAYRWHTWARGRRKWEHPSPLA-DPALSYRQVEATVQRV 178
Query 176 LPGACIRRLLYGRVLVTWRAP 196
LPGA +RRL R VTW P
Sbjct 179 LPGARVRRLAMWRYAVTWTKP 199
>gi|312197279|ref|YP_004017340.1| methyltransferase type 12 [Frankia sp. EuI1c]
gi|311228615|gb|ADP81470.1| Methyltransferase type 12 [Frankia sp. EuI1c]
Length=240
Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 80/211 (38%), Positives = 107/211 (51%), Gaps = 22/211 (10%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA-QTR 63
W+ N +Y LL +P + VLDVGCG G AARLA V AVD DAP++ +A QT
Sbjct 18 WSHNAYYQRLLLRQLPRPCRRVLDVGCGAGEFAARLAEHSDQVDAVDRDAPMIEQARQTT 77
Query 64 FANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF 123
N + + AD++T LP +DA+VS +ALHH+ T L L + PGG LA V
Sbjct 78 PDN--VHCVLADVLTDPLPAKDYDAIVSISALHHMPLPET-LPVLAAGLRPGGILAAVAL 134
Query 124 VTPSLRN--------GLWHLTSWVACGMANRV---KGKWEHS------APIKWPPPQTLH 166
LR+ + H T V +ANR+ + H P+ PP T
Sbjct 135 PRLDLRHEWPVEFVAAIAHHTLGVVF-LANRLLWGTSTFSHEHHTRTGMPVVMNPPLTTR 193
Query 167 ELRSHVRALLPGACIRRLLYGRVLVTWRAPV 197
E+ A+LPG +RRLL+ R L+TW PV
Sbjct 194 EVARQAAAVLPGVRVRRLLFWRYLLTWEKPV 224
>gi|169628387|ref|YP_001702036.1| hypothetical protein MAB_1294c [Mycobacterium abscessus ATCC
19977]
gi|169240354|emb|CAM61382.1| Conserved hypothetical protein (methytransferase?) [Mycobacterium
abscessus]
Length=198
Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 64/191 (34%), Positives = 93/191 (49%), Gaps = 4/191 (2%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN NIHY + VP VLDVGCG G+L LA V +D P LR A+
Sbjct 7 WNHNIHYQREVLRRVPAHATDVLDVGCGIGMLTRELAPLAQRVVGIDPHEPSLRIARAET 66
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
+ + + ++ + P FD + + AALHH+ D L R+ L+ PGG + +V F
Sbjct 67 SASNVEYVRGSFLEHPFPAESFDLIAAVAALHHM-DIEQGLRRMSDLLKPGGRIVIVGFA 125
Query 125 TPSLRNGLWH--LTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIR 182
LW+ L W+ R G WEH +P+ + E+R + +LPGA ++
Sbjct 126 ANRSVTDLWYDGLGFWLHRYYRLRY-GWWEHPSPVSCEGLDSHDEVRRIAQRVLPGARLQ 184
Query 183 RLLYGRVLVTW 193
RL+ R L+TW
Sbjct 185 RLVLWRHLLTW 195
>gi|111223050|ref|YP_713844.1| putative methyltransferase [Frankia alni ACN14a]
gi|111150582|emb|CAJ62283.1| Putative methyltransferase [Frankia alni ACN14a]
Length=213
Score = 96.3 bits (238), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 74/209 (36%), Positives = 102/209 (49%), Gaps = 19/209 (9%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
W+ N +Y LL +P + VLDVGCG G AARLA+R V AVD A ++ +A+ R
Sbjct 4 WSHNAYYHRLLLRQLPQPGRRVLDVGCGAGAFAARLAQRSEQVDAVDRSAEMIEQAR-RG 62
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
+ + AD++ LP +DA+ S +ALHH+ AL L + PGG LA V
Sbjct 63 TPRNVHCVLADVLADPLPGKDYDAIFSISALHHMP-LPEALGVLAAALRPGGVLAAVVLP 121
Query 125 TPSLRN--------GLWHLTSWVACGMANRVKGKWEH--------SAPIKWPPPQTLHEL 168
LR+ L H V ANR+ G+ S P+ PP T E
Sbjct 122 RRDLRHELPVEIVAALGHRLLGVVF-FANRLLGRGSSFAKDPAHASMPVVMNPPLTTREA 180
Query 169 RSHVRALLPGACIRRLLYGRVLVTWRAPV 197
A+LPG +RRLL+ R L+ W+ P+
Sbjct 181 ARQAAAVLPGVRVRRLLFWRYLLIWQKPI 209
>gi|297196954|ref|ZP_06914351.1| methyltransferase type 12 [Streptomyces sviceus ATCC 29083]
gi|197715905|gb|EDY59939.1| methyltransferase type 12 [Streptomyces sviceus ATCC 29083]
Length=204
Score = 95.1 bits (235), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 68/201 (34%), Positives = 97/201 (49%), Gaps = 17/201 (8%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N+ + VP G LDVGCGDGLLA +LA R +VT +D ++ A+
Sbjct 10 WNTNVARHPGILRSVPEGCGDALDVGCGDGLLARKLAGRAKHVTGIDKSPDMIACARESA 69
Query 65 ANAP-IRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF 123
A P + ++ D +TAELP AG+D V S +HH+ D AL R+ L+ PGGTL VV
Sbjct 70 AGDPQLTFVEGDFLTAELPAAGYDFVCSVTTIHHM-DFEAALVRMRELLRPGGTLVVVGL 128
Query 124 VTPSLRNGLWHLTSWVACGMANRV--------KGKWEHSAPIKWPPPQTLHELRSHVRAL 175
+ +T W A A + + + P+ P + ++R+ R L
Sbjct 129 AREA------SVTEWAALIAAAPIVRITKVLRRARGPRGMPVA-DPQMSYGQVRAAARLL 181
Query 176 LPGACIRRLLYGRVLVTWRAP 196
LPG RR + R + W P
Sbjct 182 LPGVRYRRHVLRRYSLAWEKP 202
>gi|340359826|ref|ZP_08682299.1| type 12 methyltransferase [Actinomyces sp. oral taxon 448 str.
F0400]
gi|339884116|gb|EGQ73938.1| type 12 methyltransferase [Actinomyces sp. oral taxon 448 str.
F0400]
Length=205
Score = 94.0 bits (232), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 76/202 (38%), Positives = 92/202 (46%), Gaps = 17/202 (8%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N+ + + L LDVGCGDGLL A LA V +D D V+ RA+ R
Sbjct 6 WNHNVAFHRRIVRDAALRGGNALDVGCGDGLLLAHLATVCRCVVGLDPDVQVVARARRRL 65
Query 65 ANAP-IRWLHADIMTAELPN--AGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
P L D+M +LP F+ V A LHH+ AL+RL LV PGG L VV
Sbjct 66 EQNPQAEVLLDDVMDPDLPQRIGTFETVSCVATLHHLP-LEPALARLSELVAPGGRLIVV 124
Query 122 TFVTPSLRNGLWHLTSWVACGMAN---RVKGKWEHSAP----IKWPPPQTLHELRSHVRA 174
LW WV +A RV G P + PP QTL E+R+
Sbjct 125 GLAA---NGSLW---DWVLSALAVLPLRVVGTLRRETPDIGVVTRPPRQTLAEIRAAASR 178
Query 175 LLPGACIRRLLYGRVLVTWRAP 196
LLPGA IRR Y R + W P
Sbjct 179 LLPGATIRRRFYYRYTLIWDRP 200
>gi|118467757|ref|YP_888968.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
gi|118169044|gb|ABK69940.1| putative methyltransferase [Mycobacterium smegmatis str. MC2
155]
Length=200
Score = 91.3 bits (225), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 71/192 (37%), Positives = 92/192 (48%), Gaps = 3/192 (1%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N Y L + VLDVGCGDGLLA RLA VTA++ D L+RA R
Sbjct 7 WNHNTAYHPWLRRIAAQHRGDVLDVGCGDGLLAQRLAPVSRSVTAIEPDPQTLQRAWVRL 66
Query 65 ANAP-IRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF 123
A+ P + D T + FD V A LHH+ D R ALS+ L+TP G +AVV
Sbjct 67 AHLPNVTVAQNDFDTFDPGTHRFDVVTMVATLHHM-DLRAALSKARELLTPTGEIAVVGL 125
Query 124 -VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIR 182
+LR+ W A + + + P + L E+R +LPGA IR
Sbjct 126 SANKTLRDWAWSGLCLPAVRLGSFCHRETRDIGVPVAEPAENLDEIRRVAADVLPGAMIR 185
Query 183 RLLYGRVLVTWR 194
R LY R L+ W+
Sbjct 186 RALYYRYLLRWQ 197
>gi|302528805|ref|ZP_07281147.1| methyltransferase type 12 [Streptomyces sp. AA4]
gi|302437700|gb|EFL09516.1| methyltransferase type 12 [Streptomyces sp. AA4]
Length=207
Score = 88.2 bits (217), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 63/195 (33%), Positives = 94/195 (49%), Gaps = 11/195 (5%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N+ + VP G LDVGCGDGLL +LA +P VT +D ++ +A++
Sbjct 20 WNTNVARHPGILRAVPGGCSTALDVGCGDGLLVRKLASVVPSVTGIDKSPEMVAQARSLS 79
Query 65 ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFV 124
+ R++ D + A+L +D + S A +HH+ D AL+R+ L+ PGG L VV
Sbjct 80 GD---RFVEGDFLAADL--GAYDFICSVATIHHL-DFEAALTRMRDLLNPGGALVVVGLA 133
Query 125 TPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP---PPQTLHELRSHVRALLPGACI 181
+ N + A + VK P P P + E+R+ + LLPG
Sbjct 134 RDA--NVTDRAATLAAAPLVRVVKTVRRAHGPDGMPERQPRMSYREVRTAAQRLLPGVRY 191
Query 182 RRLLYGRVLVTWRAP 196
RR + R +TWR P
Sbjct 192 RRHVLRRYSLTWRKP 206
>gi|120405036|ref|YP_954865.1| type 12 methyltransferase [Mycobacterium vanbaalenii PYR-1]
gi|119957854|gb|ABM14859.1| Methyltransferase type 12 [Mycobacterium vanbaalenii PYR-1]
Length=198
Score = 87.4 bits (215), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 67/200 (34%), Positives = 94/200 (47%), Gaps = 15/200 (7%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N Y L + VLD+GCGDGLLA RL VT +D D + RAQ R
Sbjct 5 WNHNTAYHPWLVGIAGEHRGDVLDIGCGDGLLAQRLLPVSRSVTLIDPDPDSVARAQARL 64
Query 65 ANAPIRWLHADIMTAELP-------NAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGT 117
A HAD+ ++ A FD + A+LHH+ R +L + L+ PGG
Sbjct 65 AG------HADVSISQQSFHDYRPGTALFDVITFVASLHHMA-LRESLRKARALLRPGGE 117
Query 118 LAVVTF-VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALL 176
LAVV S + +W A + +R+ + + P ++L E+R ++
Sbjct 118 LAVVGLSANRSASDWIWSGLCLPAVRIGSRLHRETRDIGVVVAQPRESLREIRLVSDDVI 177
Query 177 PGACIRRLLYGRVLVTWRAP 196
PGA +RR LY R L+ WR P
Sbjct 178 PGAVVRRALYYRYLLRWRKP 197
>gi|337769482|emb|CCB78195.1| SAM-dependent methyltransferase [Streptomyces cattleya NRRL 8057]
Length=209
Score = 87.0 bits (214), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 97/201 (49%), Gaps = 14/201 (6%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N HY L+ VP G + LDVGCGDGLL +RLA R VT V+ +LR A R
Sbjct 14 WNHNTHYHRLVLDAVPAGCRAALDVGCGDGLLVSRLAARAREVTGVERSPGMLRLAAERT 73
Query 65 ANAP-IRWLHADIMTAE--LPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
+ +R + AD LP G+D V + A +HH+ D A++ + L+ PGG L +V
Sbjct 74 RHLDNVRLVRADFPAPAGLLPAGGYDLVTAVAVVHHM-DFAEAVTAMRALLAPGGRLVLV 132
Query 122 TFVTPSLRNGLWHLTSWVACGM------ANRVKGKWEHSAPIKWPPPQTLHELRSHVRAL 175
RN W + A G+ A R GK + P + ++R+ R L
Sbjct 133 GLA----RNATWWDWTVSAAGVPAAWLAARRHGGKSDPPGMPVTDPALSWGQVRAAARRL 188
Query 176 LPGACIRRLLYGRVLVTWRAP 196
LPG IRR L R + W P
Sbjct 189 LPGCRIRRHLLWRWSLVWTRP 209
>gi|240170947|ref|ZP_04749606.1| putative methyltransferase [Mycobacterium kansasii ATCC 12478]
Length=208
Score = 86.3 bits (212), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 67/198 (34%), Positives = 93/198 (47%), Gaps = 11/198 (5%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N Y L + VLDVGCG+GLL RLA V +D DA + RA+ R
Sbjct 15 WNHNTAYHPWLVDIAARHHGDVLDVGCGEGLLVQRLAAVSHRVVGIDPDAGTVERARRRL 74
Query 65 A---NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
NA + D + P FD + A++HH + R AL++ L+ PGG LAVV
Sbjct 75 QSIDNASVD--RCDFQSFTAPGQSFDVITFLASIHH-QPLREALAKARRLLKPGGELAVV 131
Query 122 TF-VTPSLRNGLWHL--TSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPG 178
++R+ W L T W G +R+ G+ P + L ++R +LP
Sbjct 132 GLAANKTIRDWAWSLLCTPWARIG--SRLHGETRDIGVPVTEPNENLDQIRRVANEVLPN 189
Query 179 ACIRRLLYGRVLVTWRAP 196
A +RR LY R + WR P
Sbjct 190 AKVRRGLYYRYRLHWRDP 207
>gi|311900519|dbj|BAJ32927.1| hypothetical protein KSE_71710 [Kitasatospora setae KM-6054]
Length=231
Score = 85.9 bits (211), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 75/211 (36%), Positives = 100/211 (48%), Gaps = 23/211 (10%)
Query 4 PWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLR--RAQ 61
P++ N HY LL +P+G++ LDVGCG G A RLA R V AVD A + RA
Sbjct 10 PFDHNDHYHRLLLRHLPVGSRTALDVGCGTGRFARRLAARGVEVDAVDPSAEAIEAARAV 69
Query 62 TRFANAPI-RWLHADIMTAELPNAGFDAVVSNAALHHI--EDTRTALSRLGGLVTPGGTL 118
T A P R+ D AELP+ +D V A+LHH+ E R L + PGG L
Sbjct 70 TSAAEGPAPRFRCEDATRAELPSGHYDFVSCLASLHHMPFETVRA----LRDSLAPGGVL 125
Query 119 AVV-TFVTPSLRNGLWHL------------TSWVACGMANRVKGKWEHSAPIKWPPPQTL 165
++ + S + LW L +++ R G AP+ PP T
Sbjct 126 VILGCYPEKSRTDWLWSLAAVPVNAAARAVVAFIERARRTRPTGPNAVRAPVA-PPTMTY 184
Query 166 HELRSHVRALLPGACIRRLLYGRVLVTWRAP 196
R LLPGA +RRLL+ R L+ +RAP
Sbjct 185 AWTRQEAARLLPGARMRRLLFWRYLLLYRAP 215
>gi|302528929|ref|ZP_07281271.1| predicted protein [Streptomyces sp. AA4]
gi|302437824|gb|EFL09640.1| predicted protein [Streptomyces sp. AA4]
Length=210
Score = 84.7 bits (208), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 70/210 (34%), Positives = 105/210 (50%), Gaps = 21/210 (10%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
P++ N HY L ++P G LDVGCGDG A +LA V +D A ++ RA
Sbjct 1 MPFDHNHHYHPALLRLLPPGPGRALDVGCGDGRFARKLAAAGMTVEGIDTSAEMIARATV 60
Query 63 RFANAP--IRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
+ P + + ADI T L + + + A+LHH+ ++RL + PGG LAV
Sbjct 61 TGSPGPGTVEYRRADITTEPLEPESYAYISALASLHHVP--FETVTRLRDALAPGGVLAV 118
Query 121 VTFVTPSLRNGLW--HLTSWVACGMA-------NRVKGKWE--HSAPI--KWPPPQTLHE 167
+ PS R G + L + A +A +R+ G + AP+ K+PP L++
Sbjct 119 LGCARPS-RPGDYARELVAVPANALARLLVFAGDRLNGGPDPVAKAPVHLKFPP---LND 174
Query 168 LRSHVRALLPGACIRRLLYGRVLVTWRAPV 197
+R LLPG+ +R LL+ R L+TWR P
Sbjct 175 VRRDSARLLPGSTVRPLLFWRYLLTWRKPT 204
>gi|152966704|ref|YP_001362488.1| type 12 methyltransferase [Kineococcus radiotolerans SRS30216]
gi|151361221|gb|ABS04224.1| Methyltransferase type 12 [Kineococcus radiotolerans SRS30216]
Length=225
Score = 84.7 bits (208), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 21/200 (10%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVL---RR 59
PW+ N H+ ++ +P LDVGCG G LA RLA R +VT +D+D + RR
Sbjct 20 HPWDHNAHHHRWIERHLPDRIGTALDVGCGTGDLARRLALRAGHVTGLDVDPAGIDTARR 79
Query 60 AQTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLA 119
R + R D++TA+LP G+D V + LHH+ AL RL L+ PGGTL
Sbjct 80 LSARERDVDFRC--GDLLTADLPG-GYDVVTALTVLHHVP-FEPALRRLRQLLAPGGTLL 135
Query 120 VVTFVTPSLRNGLWHLTSWVAC-------GMANRVKGKWEH----SAPIKWPPPQTLHEL 168
V+ + HL S VA + R +G + SAP P TL E+
Sbjct 136 VIGVYREETASD--HLLSAVAVPANLVVGTVKTRRRGSAQRPVAMSAPTA-PAGTTLREI 192
Query 169 RSHVRALLPGACIRRLLYGR 188
R R +PGA +RR L+ R
Sbjct 193 RDVARRQVPGAVVRRHLFWR 212
>gi|134100186|ref|YP_001105847.1| hypothetical protein SACE_3648 [Saccharopolyspora erythraea NRRL
2338]
gi|291006595|ref|ZP_06564568.1| hypothetical protein SeryN2_18911 [Saccharopolyspora erythraea
NRRL 2338]
gi|133912809|emb|CAM02922.1| hypothetical protein SACE_3648 [Saccharopolyspora erythraea NRRL
2338]
Length=221
Score = 83.2 bits (204), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 70/207 (34%), Positives = 99/207 (48%), Gaps = 16/207 (7%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PW+ N HY A + +P LDVGCG G LA LARR V AVD D ++ A++
Sbjct 14 HPWDHNAHYHAWILRQLPARFSRALDVGCGSGDLARLLARRADEVLAVDQDPSIVEHARS 73
Query 63 RFAN-APIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
++ I + ADI ELP D + A LHH+ T T L R + PGGTL V+
Sbjct 74 LSSHRTNIDVVAADITEVELPG-DHDVITCVATLHHLPFTAT-LRRFRRALAPGGTLVVL 131
Query 122 -TFVTPSLRNGLWH--------LTSWVACGMANRVKGKWEHSAPIK---WPPPQTLHELR 169
+ + + L + W+ A R +G+ A + P T E+
Sbjct 132 GVYREQTAGDRLLSAAAAPTNLVVGWLKT-RARRRRGETGRPASMTASTKPASMTFTEIT 190
Query 170 SHVRALLPGACIRRLLYGRVLVTWRAP 196
+ RA+LPGA +RR L+ R + +RAP
Sbjct 191 AQARAVLPGAVLRRHLFWRYSLVYRAP 217
>gi|297625401|ref|YP_003687164.1| methyltransferase [Propionibacterium freudenreichii subsp. shermanii
CIRM-BIA1]
gi|296921166|emb|CBL55713.1| methyltransferase [Propionibacterium freudenreichii subsp. shermanii
CIRM-BIA1]
Length=199
Score = 82.0 bits (201), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 63/202 (32%), Positives = 96/202 (48%), Gaps = 18/202 (8%)
Query 5 WNANIHYDA-LLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTR 63
WN N Y A LLDA+ P G VLD+GCGDGLL +LA + V +D D + +A+ R
Sbjct 5 WNHNTAYHAELLDAVPPSGGD-VLDIGCGDGLLVEKLATKATRVIGLDPDPRAINQARRR 63
Query 64 FANAP-IRWLHADIMTA-ELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
P + + +TA EL FD + A LHH+ AL ++ + PGG L +V
Sbjct 64 LTETPNAQVVLGSFLTAPELDGQSFDLITCVATLHHMP-LFAALEQMNAKLKPGGGLCIV 122
Query 122 TFVTPSLRNGLWHLTSWVACG-------MANRVKGKWEHSAPIKWPPPQTLHELRSHVRA 174
S W W+ G + ++++G+ + P ++L E+R
Sbjct 123 GL---SANKTAW---DWIVSGVHVLPIRLLSKLRGESGYPGMAVARPSESLAEIRRISSK 176
Query 175 LLPGACIRRLLYGRVLVTWRAP 196
+LP + +RR + R +TW P
Sbjct 177 VLPASRVRRRFWYRYTLTWTKP 198
>gi|254777576|ref|ZP_05219092.1| methyltransferase type 12 [Mycobacterium avium subsp. avium ATCC
25291]
Length=209
Score = 81.3 bits (199), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 66/196 (34%), Positives = 89/196 (46%), Gaps = 7/196 (3%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
+ WN N Y L + VLDVGCGDGLLAARLA V +D D +RRA
Sbjct 9 EYWNHNSAYHPWLVGIAARHRGDVLDVGCGDGLLAARLAPVSRSVVGIDADPASVRRAAR 68
Query 63 RFA---NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLA 119
R NA ++ A + P FD + A+LHH+ R AL + ++ P G LA
Sbjct 69 RLERVDNACVQ--QARFQDFQAPAQSFDLITFVASLHHVP-LRDALGKARQMLRPAGELA 125
Query 120 VVTF-VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPG 178
VV S+ + LW A + + P ++L E+R +LPG
Sbjct 126 VVGLSANKSVADWLWAGLCLPVVRAAGLLHRETRDIGVAVADPRESLDEIRRAAEDVLPG 185
Query 179 ACIRRLLYGRVLVTWR 194
A IRR +Y R + WR
Sbjct 186 AVIRRGVYYRYRLLWR 201
>gi|333022936|ref|ZP_08451000.1| putative methyltransferase [Streptomyces sp. Tu6071]
gi|332742788|gb|EGJ73229.1| putative methyltransferase [Streptomyces sp. Tu6071]
Length=228
Score = 81.3 bits (199), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 69/210 (33%), Positives = 97/210 (47%), Gaps = 24/210 (11%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
+PW+ N HY + +P LDVGCG G LA LARR VT +D D ++ +A+
Sbjct 27 RPWDHNAHYHRAILRRLPDHRGAALDVGCGSGDLARLLARRADAVTGIDTDPAIVAKARA 86
Query 63 RF-ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
P+ + AD + E + V AALHH+ AL+ + PGGTL +V
Sbjct 87 ATPETVPVAFATADALDEEAAPGPYTVVTCVAALHHLPLAE-ALTSFRARLAPGGTLVIV 145
Query 122 TF---VTPSLRNGLWHLTSWVACGMANRVKGKWEH------------SAPIKWPPPQTLH 166
TP+ R S +A +AN W+H +AP + P L
Sbjct 146 GLHREETPADRA-----VSLLAV-VANTAVAWWKHPGGGKGARPLARTAPTR-PATTGLA 198
Query 167 ELRSHVRALLPGACIRRLLYGRVLVTWRAP 196
E+R +LPGA +RR L+ R L+ WR P
Sbjct 199 EIRRTAARILPGARVRRRLFWRYLLVWRRP 228
>gi|318059073|ref|ZP_07977796.1| putative methyltransferase [Streptomyces sp. SA3_actG]
Length=234
Score = 79.7 bits (195), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 68/210 (33%), Positives = 97/210 (47%), Gaps = 24/210 (11%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
+PW+ N HY + +P LDVGCG G LA LARR VT +D D ++ +A+
Sbjct 33 RPWDHNAHYHRAILRRLPHHRGAALDVGCGSGDLARLLARRADAVTGIDTDPGIVAKARA 92
Query 63 RF-ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
P+ + AD + E + V AALHH+ AL+ + PGGTL +V
Sbjct 93 ATPETVPVAFATADALDEEAAPGPYTVVTCVAALHHLPLA-EALTSFRARLAPGGTLVIV 151
Query 122 TF---VTPSLRNGLWHLTSWVACGMANRVKGKWEH------------SAPIKWPPPQTLH 166
TP+ R S +A +AN W+H +AP + P L
Sbjct 152 GLHREETPADRA-----VSLLAV-VANSAVAWWKHPGGGRGARPLAMTAPTR-PATTGLA 204
Query 167 ELRSHVRALLPGACIRRLLYGRVLVTWRAP 196
E+R +LPGA +RR L+ R ++ WR P
Sbjct 205 EIRRTAARILPGARVRRRLFWRYVLVWRRP 234
>gi|23008602|ref|ZP_00049980.1| COG0500: SAM-dependent methyltransferases [Magnetospirillum magnetotacticum
MS-1]
Length=249
Score = 79.7 bits (195), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 72/224 (33%), Positives = 98/224 (44%), Gaps = 32/224 (14%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PWN N H+ + VP + VLDVGCG G+L RL R V +D DA ++ +A+
Sbjct 27 HPWNHNEHFHGWVVRRVPHDARVVLDVGCGTGVLLGRLRARAAEVHGIDADAGMVAQARA 86
Query 63 RFANAP---IRWLHADIMTA----------------ELPNAGFDAVVSNAALHHIEDTRT 103
R A P +R L D + + G+DAV A LHH+E
Sbjct 87 RHAADPAVTVRRLRFDDVRSPDDVRSPGGTPGPGTGSPEQRGYDAVTMVAVLHHLE-LDE 145
Query 104 ALSRLGGLVTPGGTLAVVTFV-TPSLRNGLWHLTSWVACGMANRVK----------GKWE 152
AL L+ PGG L VV + R+ L S + + VK G
Sbjct 146 ALRHARDLLAPGGRLLVVGLARVATARDLAVDLASALLNPLVGLVKHPRRARPDDPGPDA 205
Query 153 HSAPIKWPPPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAP 196
P++ P T+ E+ RALLPGA +RR L+ R + W AP
Sbjct 206 PGMPVR-DPRHTVDEVARAARALLPGARVRRRLFFRCTLEWTAP 248
>gi|326202811|ref|ZP_08192678.1| Methyltransferase type 11 [Clostridium papyrosolvens DSM 2782]
gi|325986888|gb|EGD47717.1| Methyltransferase type 11 [Clostridium papyrosolvens DSM 2782]
Length=222
Score = 79.7 bits (195), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 54/206 (27%), Positives = 95/206 (47%), Gaps = 12/206 (5%)
Query 1 VDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRA 60
V++ WN N Y L + + +L++GCG G L+ LA++ +V AVD+ ++ +A
Sbjct 18 VEERWNHNNCYFKNLMKYLHEDNELILEIGCGKGELSNMLAKKSEHVIAVDLADKMIEKA 77
Query 61 QTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
+++ I ++ +I+ E DA+V+ A HH+ L L L PGG L V
Sbjct 78 ISQYGYKNIDFISKNILDMEFEENSLDAIVTTATAHHLPYEWLLLFALKTL-KPGGKLIV 136
Query 121 VT-FVTPSLRNGLWHLTSWVACGMANRVKGKW-----EHSAPI-----KWPPPQTLHELR 169
+ + + + ++L + + N V K EH+ + + TL E++
Sbjct 137 LDLYKVKTFTDMFFNLLAVIPNVFMNIVNNKKIKTGDEHTREVWKRHGEHDTYMTLKEIK 196
Query 170 SHVRALLPGACIRRLLYGRVLVTWRA 195
+ LP IRR L+ R L+ W
Sbjct 197 LLAKGHLPEVIIRRKLFWRYLMVWEK 222
>gi|336117301|ref|YP_004572068.1| hypothetical protein MLP_16510 [Microlunatus phosphovorus NM-1]
gi|334685080|dbj|BAK34665.1| hypothetical protein MLP_16510 [Microlunatus phosphovorus NM-1]
Length=217
Score = 79.3 bits (194), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 64/202 (32%), Positives = 91/202 (46%), Gaps = 11/202 (5%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PW+ N H+ + + A +P + LDVGCG G L A LA +V D D + +A
Sbjct 8 HPWSHNDHFHSWILATMPRPCRRALDVGCGRGELVAALAPHADHVVGNDADPAMREQASQ 67
Query 63 RFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVT 122
R A P + + T + FD V A LHH+ D AL + L++PGG V
Sbjct 68 RCAGLPNVTITSGDWTDS--DGQFDLVTMVAVLHHL-DVAEALHDVRRLLSPGGRFLAVG 124
Query 123 FVTP-SLRNGLWHLTSWVACGMANRVKGKW----EHSAPIKWP---PPQTLHELRSHVRA 174
P + R+ W + S + + VK W + P +P P + ELR +
Sbjct 125 LARPHTARDHAWDIASMITNPIIGYVKHPWPSRTDGPQPSPFPVRDPMLSFDELRRLLDD 184
Query 175 LLPGACIRRLLYGRVLVTWRAP 196
+LPGA IRR L R + W P
Sbjct 185 VLPGAIIRRQLGFRHTIAWTKP 206
>gi|342859512|ref|ZP_08716166.1| type 12 methyltransferase [Mycobacterium colombiense CECT 3035]
gi|342133753|gb|EGT86956.1| type 12 methyltransferase [Mycobacterium colombiense CECT 3035]
Length=203
Score = 78.6 bits (192), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 67/198 (34%), Positives = 93/198 (47%), Gaps = 9/198 (4%)
Query 2 DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQ 61
+ WN N Y L + VLDVGCG+GLLAARLA V +D DA + RA
Sbjct 8 EDYWNHNTAYHPWLVDLASRHRGDVLDVGCGEGLLAARLAAVSRSVVGIDADAAAVLRAS 67
Query 62 TR---FANAPI-RWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGT 117
R NA + R D+ AE FD + A+LHH+ R L + ++ P G
Sbjct 68 QRLRALGNASVERRRFEDLQQAE---RAFDLITFVASLHHLP-LRDTLWKARHMLRPAGE 123
Query 118 LAVVTF-VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALL 176
LAVV S+ + +W A + +R+ + + P ++L E+R +L
Sbjct 124 LAVVGLSANTSVADWVWAGLCLPAVRVGSRLHRETRNIGVAVADPRESLAEIRRTAEDVL 183
Query 177 PGACIRRLLYGRVLVTWR 194
PGA IRR LY R + WR
Sbjct 184 PGARIRRGLYYRYRLLWR 201
>gi|256824037|ref|YP_003147997.1| ubiquinone/menaquinone biosynthesis methylase [Kytococcus sedentarius
DSM 20547]
gi|256687430|gb|ACV05232.1| methylase involved in ubiquinone/menaquinone biosynthesis [Kytococcus
sedentarius DSM 20547]
Length=233
Score = 78.2 bits (191), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 65/202 (33%), Positives = 85/202 (43%), Gaps = 10/202 (4%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PWN N + + +P LD+GCG G LAA LA R +V DID P +R A T
Sbjct 25 HPWNHNEAFHPWILTRLPARRGRALDLGCGRGELAALLAERFEHVHGTDID-PAMREAAT 83
Query 63 RFANAPIRWLHADIMTAELPNA-GFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
R D +L G D V A LHH+ D AL ++ ++ PGG V
Sbjct 84 RRCAGLPNVSIDDARLGQLAEGEGVDLVTMVAVLHHL-DLDEALRQVAAILRPGGRFLCV 142
Query 122 TFVTPSLRNGL-WHLTSWVACGMANRVKGKWEHSAPIKW------PPPQTLHELRSHVRA 174
P+ L W S V + V+ W P W P +++ +R R
Sbjct 143 GLARPAGPGDLAWEAASVVTNPVIGYVRHPWVSQGPPPWGKVPMADPAESVGAIRRAART 202
Query 175 LLPGACIRRLLYGRVLVTWRAP 196
LPGA IRR L R + W P
Sbjct 203 ALPGARIRRRLGFRYTLEWTNP 224
>gi|300788556|ref|YP_003768847.1| methyltransferase [Amycolatopsis mediterranei U32]
gi|299798070|gb|ADJ48445.1| methyltransferase [Amycolatopsis mediterranei U32]
gi|340530161|gb|AEK45366.1| methyltransferase [Amycolatopsis mediterranei S699]
Length=211
Score = 77.8 bits (190), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 70/204 (35%), Positives = 98/204 (49%), Gaps = 17/204 (8%)
Query 4 PWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTR 63
P+N N HY LL ++P G LDVGCG G A RLA V AVD+ A ++ A
Sbjct 2 PFNHNDHYHPLLLDLLPPGPGIALDVGCGTGRFARRLAATGMAVEAVDVSAAMVEAAAGL 61
Query 64 FANAP--IRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
+ P I + AD+ T LP + +D + A+LHH+ +++L + PGG L V+
Sbjct 62 GSPGPGEIVYRQADVTTDALPESHYDYISCVASLHHM--PFETVAKLRRALVPGGVLVVL 119
Query 122 TFVTPSLRNGLWHLT---------SWVACGMANRVKGKWEH--SAPIKWPPPQTLHELRS 170
PS W L + + R+ G E AP+ P TL ELR
Sbjct 120 GLAKPSTPAD-WALALAAVPVDALARLVVHAGERLNGGPEEGPKAPVVDDYP-TLAELRR 177
Query 171 HVRALLPGACIRRLLYGRVLVTWR 194
LLPG+ +R LL+ R L+T+R
Sbjct 178 ESARLLPGSTVRPLLFWRTLITYR 201
>gi|295835362|ref|ZP_06822295.1| methyltransferase [Streptomyces sp. SPB74]
gi|295825447|gb|EFG64255.1| methyltransferase [Streptomyces sp. SPB74]
Length=253
Score = 77.8 bits (190), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 68/202 (34%), Positives = 96/202 (48%), Gaps = 9/202 (4%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
+PW+ N HY + +P VLDVGCG G LA LARR VTA+D D ++ RA+
Sbjct 53 RPWDHNAHYHRAILRRLPRRPGPVLDVGCGSGDLARLLARRASAVTAIDADPGIVARARE 112
Query 63 RFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVT 122
A + + AD + E + AV A LHH+ A + + PGG L VV
Sbjct 113 ASPAAAVTFTVADALDREAAPGPYTAVTCVAVLHHLPLA-EAFASFRARLAPGGVLVVVG 171
Query 123 F---VTPSLRN-GLWHLTSWVACGMANR-VKGKWEHSAPI--KWPPPQT-LHELRSHVRA 174
TP+ R L L + A A V G + + P Q L ++R V+
Sbjct 172 LYRETTPADRAVSLLALLANTAIAWAKHPVAGTSPRPLAMTARTRPAQVGLAQIRRTVQE 231
Query 175 LLPGACIRRLLYGRVLVTWRAP 196
+LPGA +RR L+ R ++ W+ P
Sbjct 232 VLPGARVRRRLFWRYVLEWKRP 253
>gi|256393722|ref|YP_003115286.1| methyltransferase type 11 [Catenulispora acidiphila DSM 44928]
gi|256359948|gb|ACU73445.1| Methyltransferase type 11 [Catenulispora acidiphila DSM 44928]
Length=220
Score = 77.4 bits (189), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 63/201 (32%), Positives = 93/201 (47%), Gaps = 12/201 (5%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N+ + A + +P + LDVGCGDGLLA +LA R +V A+D A + +A+ R
Sbjct 5 WNHNVAHHARIVRAMPPNCRSALDVGCGDGLLAQKLATRANWVVALDASADMAEQARRRT 64
Query 65 ANAPIRWLHADIMTA----ELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
A + + AD + A LP F V S A LHH+ D AL + L+ PGG LAV
Sbjct 65 AELDVEVVEADFLAAVRDGVLPRHSFGFVTSVAVLHHL-DPEAALQAMASLLEPGGRLAV 123
Query 121 VTFVTPSLRNGLWHLTSWVACGMANRVK----GK-WEHSAPIKWPPPQTLHELRSHVRAL 175
R+ + L + + ++ GK P+ + + + +
Sbjct 124 AGLAMS--RSAVDWLIAAAQLPIVQTIRLAHGGKSGPDGMPMNFDDIPSWAQSKRTALDT 181
Query 176 LPGACIRRLLYGRVLVTWRAP 196
LPGA R L R ++ W AP
Sbjct 182 LPGARWHRTLQLRYMIEWTAP 202
>gi|91199610|emb|CAI77964.1| putative SAM-dependent methyltransferase [Streptomyces ambofaciens
ATCC 23877]
gi|96771657|emb|CAI78238.1| putative SAM-dependent methyltransferase [Streptomyces ambofaciens
ATCC 23877]
gi|117164205|emb|CAJ87745.1| putative SAM-dependent methyltransferase [Streptomyces ambofaciens
ATCC 23877]
gi|126347317|emb|CAJ89023.1| putative SAM-dependent methyltransferase [Streptomyces ambofaciens
ATCC 23877]
Length=218
Score = 76.6 bits (187), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 65/209 (32%), Positives = 91/209 (44%), Gaps = 30/209 (14%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PW+ N HY + +P LDVG G G LA +A R V A+D D + RAQ
Sbjct 19 HPWDHNAHYHRWIMRQLPRSFGTALDVGSGTGDLARLMATRAAAVDAIDSDPATVARAQA 78
Query 63 RF-ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
+AP+ + AD +T +P A +D + AALHH+ AL+ + PGGTL VV
Sbjct 79 MTPPDAPVTFTTADALTG-IPAASYDVITCVAALHHLP-FNDALAHFRRHLAPGGTLVVV 136
Query 122 TFVTPSLRNGLWHLTS-----WVACGMANRVKGKW------------EHSAPIKWPPPQT 164
GLWH + A + W +AP++ P
Sbjct 137 ---------GLWHAQTPGDHLLSAAALPLNAATGWIKNKGRTALPPASMTAPVR-PATMG 186
Query 165 LHELRSHVRALLPGACIRRLLYGRVLVTW 193
E+ R +LPGA +RR L+ R + W
Sbjct 187 FAEIDRETRHVLPGARLRRRLFWRYTLVW 215
>gi|257068133|ref|YP_003154388.1| ubiquinone/menaquinone biosynthesis methylase [Brachybacterium
faecium DSM 4810]
gi|256558951|gb|ACU84798.1| methylase involved in ubiquinone/menaquinone biosynthesis [Brachybacterium
faecium DSM 4810]
Length=268
Score = 76.3 bits (186), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 70/226 (31%), Positives = 98/226 (44%), Gaps = 37/226 (16%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PW+ N H+ + +P G Q VLDVGCG G L A L R ++ +D D + A
Sbjct 47 HPWDHNAHFHPWILRSLPPGAQRVLDVGCGRGDLLAALRGRSEHLEGIDPDPGMAAAAAA 106
Query 63 RFANAPIRWLHADIMTAELPNAG----FDAVVSNAALHHIEDTRTALSRLGGLVTPGGTL 118
P +H + + + G +DAV A+LHH + AL++ L+ PGG L
Sbjct 107 ALQEVPGAEVHRRTLVEHVQHPGTAAAYDAVTFVASLHH-QQVPQALAQARHLLRPGGRL 165
Query 119 AVVTFVTPS-LRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPP---------PQ----- 163
VVT V P+ + LW +A + N G +H P++ P P+
Sbjct 166 LVVTLVRPAGPADQLWD----IADALTNPAIGLVKHPRPVQGAPVPARPGPVTPEVGEAE 221
Query 164 -------------TLHELRSHVRALLPGACIRRLLYGRVLVTWRAP 196
TL LR R LLPGA IRR RV + W+ P
Sbjct 222 PSSAAMPVRDPDLTLAALREAARHLLPGARIRRREGFRVTLRWQRP 267
>gi|257055280|ref|YP_003133112.1| methyltransferase family protein [Saccharomonospora viridis DSM
43017]
gi|256585152|gb|ACU96285.1| methyltransferase family protein [Saccharomonospora viridis DSM
43017]
Length=203
Score = 76.3 bits (186), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 67/205 (33%), Positives = 100/205 (49%), Gaps = 17/205 (8%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
P+N N HY LL +VP G + LDVGCG G A +LA + V A+D A VL A+
Sbjct 1 MPFNHNAHYHPLLLRLVPPGARRALDVGCGLGGFARKLAAKGLDVDAIDQAAEVLEPARA 60
Query 63 RFANAP--IRWLHADIMTAELPNAGFDAVVSNAALHHIE-DTRTALSRLGGLVTPGGTLA 119
+ P I + AD+ LP +D + A+LHH+ DT T L + P G LA
Sbjct 61 LGSPGPGTITYHRADVTAHPLPPRHYDIITCIASLHHLPFDTVTTLR---DALAPHGVLA 117
Query 120 VVTFVTPS--------LRNGLWHLTSWVACGMANRVKGKWE--HSAPIKWPPPQTLHELR 169
V+ PS L + ++ + +A R+ G + AP++ +L+++R
Sbjct 118 VLGLAKPSTPRDWAIWLGSLPFNHVAKAVVSVAERLNGGADPLPEAPVR-DEGMSLNQIR 176
Query 170 SHVRALLPGACIRRLLYGRVLVTWR 194
LLPG+ IR L + R L+ +R
Sbjct 177 REAARLLPGSRIRVLPFWRYLLVYR 201
>gi|302387451|ref|YP_003823273.1| Methyltransferase type 11 [Clostridium saccharolyticum WM1]
gi|302198079|gb|ADL05650.1| Methyltransferase type 11 [Clostridium saccharolyticum WM1]
Length=224
Score = 74.3 bits (181), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 56/207 (28%), Positives = 88/207 (43%), Gaps = 18/207 (8%)
Query 2 DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQ 61
D WN N Y L VP G LD+GCG G L+A L++ V AVD+ ++ A+
Sbjct 20 DPKWNHNNCYFPYLLQHVPAGVGTCLDIGCGKGELSALLSKNAKKVIAVDLADKMIEYAR 79
Query 62 TRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
+ A I ++ +I+ + FD ++S A HH+ L + PGG L ++
Sbjct 80 SNNAADNIEYICGNILDMNYATSSFDIIISTATAHHLP-YDWLLEFAKDKLRPGGKLILL 138
Query 122 TFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPP--------------QTLHE 167
N + W + N + ++ + K P T+HE
Sbjct 139 DLAKA---NSIADHFVWGFAALPNVIMNLIKNGSLHKDDPHTTAVWRKHGEHDSYMTIHE 195
Query 168 LRSHVRALLPGACIRRLLYGRVLVTWR 194
+RS V LPGA + R L+ R + W+
Sbjct 196 IRSFVAQHLPGAIVHRKLFWRYSLIWQ 222
>gi|326776861|ref|ZP_08236126.1| Methyltransferase type 11 [Streptomyces cf. griseus XylebKG-1]
gi|326657194|gb|EGE42040.1| Methyltransferase type 11 [Streptomyces griseus XylebKG-1]
Length=223
Score = 74.3 bits (181), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 62/203 (31%), Positives = 93/203 (46%), Gaps = 16/203 (7%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PW+ N HY + +P LDVG G G LA LA R V +D+D ++ RA+
Sbjct 19 HPWDHNAHYHRWILRRLPGRFTGALDVGSGSGDLARLLATRAEAVHGIDVDPAIVERARE 78
Query 63 RFA-NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
R A AP+ + D + ++P+ +D + A +HH+ AL+R L+ PGGTL +V
Sbjct 79 RTAPGAPVTFSVGDALE-DVPSGLYDVITCVATVHHLP-LGEALTRFRRLLAPGGTLIIV 136
Query 122 TFVTPSLRNGLWHLTSWVAC----------GMANRVKGKWEHSAPIKWPPPQTLHELRSH 171
P R+ HL VA R +AP + P ++
Sbjct 137 GLYRP--RSLSDHLIDAVALPSNIAMAWIKNKGRRAPRPVAMTAPTR-PATTAFPDIVRD 193
Query 172 VRALLPGACIRRLLYGRVLVTWR 194
R +LPGA +RR L+ R + W+
Sbjct 194 ARHVLPGARLRRRLFWRYTLVWK 216
>gi|182436232|ref|YP_001823951.1| putative methyltransferase [Streptomyces griseus subsp. griseus
NBRC 13350]
gi|178464748|dbj|BAG19268.1| putative methyltransferase [Streptomyces griseus subsp. griseus
NBRC 13350]
Length=223
Score = 72.8 bits (177), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 63/203 (32%), Positives = 92/203 (46%), Gaps = 16/203 (7%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQT 62
PW+ N HY + +P LDVG G G LA LA R V +DID ++ RA+
Sbjct 19 HPWDHNAHYHRWILRRLPGRFTGALDVGSGSGDLARLLATRAEAVHGIDIDPTIVERARE 78
Query 63 RFA-NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVV 121
R A AP+ + D + ++P+ +D + A +HH+ AL+ L+ PGGTL VV
Sbjct 79 RTAPGAPVTFSVGDALE-DVPSGLYDVITCVATVHHLP-LGEALTHFRRLLAPGGTLIVV 136
Query 122 TFVTPSLRNGLWHLTSWVAC----------GMANRVKGKWEHSAPIKWPPPQTLHELRSH 171
P R+ HL VA R +AP + P ++
Sbjct 137 GLYRP--RSLSDHLIDAVALPSNIAMAWIKNKGRRAPRPVAMTAPTR-PATTAFPDIVRD 193
Query 172 VRALLPGACIRRLLYGRVLVTWR 194
R +LPGA +RR L+ R + W+
Sbjct 194 ARHVLPGARLRRRLFWRYTLVWK 216
>gi|302335032|ref|YP_003800239.1| Methyltransferase type 11 [Olsenella uli DSM 7084]
gi|301318872|gb|ADK67359.1| Methyltransferase type 11 [Olsenella uli DSM 7084]
Length=215
Score = 72.4 bits (176), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 66/199 (34%), Positives = 91/199 (46%), Gaps = 12/199 (6%)
Query 5 WNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRF 64
WN N Y + L + L LDVGCGDG L LA +V V+ D R A R
Sbjct 19 WNHNSAYYSELVSDAALRGGVALDVGCGDGALLELLAGVCRHVVGVEADPATARTAAGRV 78
Query 65 ANAPIRWLHADIMTAE-LPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF 123
A + + D M A+ FD + A LHH+ TAL R+ L+ PGG L VV
Sbjct 79 AGSGT-VICGDFMAAQDFAPEEFDTITCVACLHHMP-LETALVRMAELLRPGGRLLVVGL 136
Query 124 VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP-----PPQTLHELRSHVRALLPG 178
+ + W L++ + ++ RV G W H P ++L E+R+ LPG
Sbjct 137 -SANKTIADWLLSALMV--VSARVSG-WLHREGTYRGMRVARPCESLDEIRAVAGERLPG 192
Query 179 ACIRRLLYGRVLVTWRAPV 197
A +RR LY R + W P+
Sbjct 193 ALVRRRLYWRYSLEWTKPL 211
>gi|311404573|gb|ADP94233.1| TunM [Streptomyces chartreusis NRRL 3882]
gi|341904729|gb|AEL00532.1| methyltransferase type 12 [Streptomyces chartreusis NRRL 3882]
Length=216
Score = 72.0 bits (175), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 64/208 (31%), Positives = 95/208 (46%), Gaps = 21/208 (10%)
Query 4 PWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTR 63
P+N N HY LL +P + L+VGCG G A +LA R V A+D+D V+ A+
Sbjct 2 PFNHNDHYHDLLLRELPESCRRALEVGCGTGRFAQKLALRGIEVDAIDVDNDVVTAAREM 61
Query 64 FAN----APIRWLHADIMTAELPNAGFDAVVSNAALHH-----IEDTRTALSRLGGLVTP 114
+ IR+ ADI L +D + A++HH ++ R +L+ G LV
Sbjct 62 NSTLDLPRQIRFERADITHLTLTPDTYDYIACLASIHHVPFETVQKLRASLTTNGVLVIL 121
Query 115 G----GTL---AVVTFVTPSLRNGLWHLTSWVACGMANRV--KGKWEHSAPIKWPPPQTL 165
G T+ A+ P N +W + + +G SAP+ PP +L
Sbjct 122 GCYREATIWDHAISLLAVPV--NAIWRAAVFFRESWSGSRPDRGTQSPSAPVA-PPSMSL 178
Query 166 HELRSHVRALLPGACIRRLLYGRVLVTW 193
E+R LPG IRRLL+ R L+ +
Sbjct 179 AEIREDSAEYLPGRRIRRLLFWRYLLVF 206
>gi|296139222|ref|YP_003646465.1| type 12 methyltransferase [Tsukamurella paurometabola DSM 20162]
gi|296027356|gb|ADG78126.1| Methyltransferase type 12 [Tsukamurella paurometabola DSM 20162]
Length=223
Score = 70.5 bits (171), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 61/165 (37%), Positives = 80/165 (49%), Gaps = 15/165 (9%)
Query 3 QPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQ- 61
P++ N ++ + +P + LDVG G+GLLAARLA R +V A DID P +R A
Sbjct 28 HPYSHNDYFHPWILKNLPQRRRRALDVGSGEGLLAARLAERFEHVDAADID-PAMRSATA 86
Query 62 TRFANAPIRWLHA-DIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAV 120
R A P+ L D E +D + AALHH+ R +L R L+ PGG L V
Sbjct 87 ERCAALPVALLDGFDCAEGE-----YDLITMVAALHHL-PLRESLLRCRELLAPGGRLLV 140
Query 121 VTFVTPSLRNG--LWHLTSWVACGMANRVKGKWEHSAPIKWPPPQ 163
V +L +W L S V N V G EH P + P PQ
Sbjct 141 VGLARQTLEPADLIWELGSAV----LNPVIGVIEHPRPHRGPRPQ 181
>gi|254820551|ref|ZP_05225552.1| putative methyltransferase [Mycobacterium intracellulare ATCC
13950]
Length=203
Score = 70.5 bits (171), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 67/203 (34%), Positives = 87/203 (43%), Gaps = 19/203 (9%)
Query 2 DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQ 61
D WN N Y L + VLDVGCG+GLLA RLA V +D D + RA
Sbjct 8 DDYWNHNSAYHPWLVGLAARRHGDVLDVGCGEGLLAQRLAPVSRSVVGLDADPVSVWRAA 67
Query 62 TRF---ANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTL 118
R NA + H + +D + A+LHH+ R AL + ++ P G L
Sbjct 68 QRLQSIGNASVE--HGRFEDLDEAERRYDLITFVASLHHLP-LRDALHKARQMLRPAGQL 124
Query 119 AVVTFVTPSLRNGLWHLTSWVACGM---ANRVKGKW-EHSAPIKWP---PPQTLHELRSH 171
AVV + WV G+ RV G + I P P + L E+R
Sbjct 125 AVVGLSANK------SIADWVWAGLCVPGARVGGLLHRETRDIGVPVADPREGLDEIRRV 178
Query 172 VRALLPGACIRRLLYGRVLVTWR 194
+LPGA IRR LY R + WR
Sbjct 179 AADVLPGAAIRRGLYYRYRLLWR 201
>gi|302549463|ref|ZP_07301805.1| methyltransferase type 12 [Streptomyces viridochromogenes DSM
40736]
gi|302467081|gb|EFL30174.1| methyltransferase type 12 [Streptomyces viridochromogenes DSM
40736]
Length=218
Score = 70.5 bits (171), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 67/205 (33%), Positives = 87/205 (43%), Gaps = 20/205 (9%)
Query 2 DQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQ 61
D+PW+ N H+ + +P LDVGCG G LA LA R V VD D + RA+
Sbjct 18 DRPWDHNAHFHRWILRQLPGRVGSALDVGCGSGDLARLLAHRAERVHGVDADPAITARAR 77
Query 62 TRFAN-APIRWLHADIMTAELPNAGFDAVVSNAALHHI---EDTRTALSRLGGLVTPGGT 117
AP+ + AD LP+ +D + AALHH+ E R RL PGGT
Sbjct 78 ELTPKAAPVTYTVAD-APGGLPDGPYDVITCVAALHHLPFAESLRAFRDRLA----PGGT 132
Query 118 LAVVTFVTPSLRNGLWHLTSWVA----CGMANRVKGKWEHSAPIKW-----PPPQTLHEL 168
L +V R HL + GMA P+ P T E+
Sbjct 133 LVIVGVARE--RTPADHLLGVASIPLNIGMALLKNRGRPAPRPVAMTARTSPADMTFPEI 190
Query 169 RSHVRALLPGACIRRLLYGRVLVTW 193
RA+LPGA RR L+ R + W
Sbjct 191 VREARAVLPGARPRRRLFWRYTLVW 215
Lambda K H
0.324 0.138 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 208621361780
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40