BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0096 Length=463 Score E Sequences producing significant alignments: (Bits) Value gi|15839476|ref|NP_334513.1| PPE family protein [Mycobacterium t... 908 0.0 gi|254366552|ref|ZP_04982596.1| PPE family protein [Mycobacteriu... 905 0.0 gi|289572676|ref|ZP_06452903.1| PPE family protein [Mycobacteriu... 905 0.0 gi|289747863|ref|ZP_06507241.1| PPE family protein [Mycobacteriu... 905 0.0 gi|289441465|ref|ZP_06431209.1| PPE family protein [Mycobacteriu... 904 0.0 gi|31791274|ref|NP_853767.1| PPE family protein [Mycobacterium b... 903 0.0 gi|167968254|ref|ZP_02550531.1| PPE family protein [Mycobacteriu... 894 0.0 gi|340625132|ref|YP_004743584.1| PPE family protein [Mycobacteri... 799 0.0 gi|294992941|ref|ZP_06798632.1| PPE family protein [Mycobacteriu... 534 1e-149 gi|15828079|ref|NP_302342.1| PPE-family protein [Mycobacterium l... 499 4e-139 gi|118619893|ref|YP_908225.1| PPE family protein [Mycobacterium ... 494 1e-137 gi|183980293|ref|YP_001848584.1| PPE family protein, PPE1 [Mycob... 467 2e-129 gi|559908|emb|CAA86359.1| unknown [Mycobacterium leprae] 369 7e-100 gi|169627772|ref|YP_001701421.1| PPE-family protein [Mycobacteri... 358 1e-96 gi|169629340|ref|YP_001702989.1| PPE family protein [Mycobacteri... 222 1e-55 gi|342859230|ref|ZP_08715884.1| hypothetical protein MCOL_10138 ... 212 1e-52 gi|240168498|ref|ZP_04747157.1| PPE family protein, PPE4 [Mycoba... 209 7e-52 gi|240172392|ref|ZP_04751051.1| PPE protein [Mycobacterium kansa... 206 6e-51 gi|333988934|ref|YP_004521548.1| PPE family protein [Mycobacteri... 205 1e-50 gi|296167589|ref|ZP_06849914.1| PPE family protein [Mycobacteriu... 205 1e-50 gi|183980812|ref|YP_001849103.1| PPE family protein [Mycobacteri... 204 3e-50 gi|169627152|ref|YP_001700801.1| PPE family protein [Mycobacteri... 203 5e-50 gi|183983621|ref|YP_001851912.1| PPE family protein [Mycobacteri... 199 9e-49 gi|340625294|ref|YP_004743746.1| PPE family protein [Mycobacteri... 199 1e-48 gi|323717087|gb|EGB26297.1| PPE family protein [Mycobacterium tu... 198 1e-48 gi|339296965|gb|AEJ49075.1| PPE family protein [Mycobacterium tu... 198 1e-48 gi|183983105|ref|YP_001851396.1| PPE family protein, PPE37 [Myco... 197 3e-48 gi|296165161|ref|ZP_06847709.1| PPE family protein [Mycobacteriu... 196 5e-48 gi|183984239|ref|YP_001852530.1| PPE family protein [Mycobacteri... 196 9e-48 gi|289748258|ref|ZP_06507636.1| PPE family protein [Mycobacteriu... 196 9e-48 gi|31793303|ref|NP_855796.1| PPE family protein [Mycobacterium b... 195 1e-47 gi|289441176|ref|ZP_06430920.1| PPE family protein [Mycobacteriu... 195 1e-47 gi|240173305|ref|ZP_04751963.1| PPE family protein, PPE3 [Mycoba... 194 3e-47 gi|57116948|ref|YP_177861.1| PPE family protein [Mycobacterium t... 194 4e-47 gi|340627132|ref|YP_004745584.1| PPE family protein [Mycobacteri... 194 4e-47 gi|289447743|ref|ZP_06437487.1| PPE family protein [Mycobacteriu... 193 5e-47 gi|118468729|ref|YP_885030.1| PPE family protein [Mycobacterium ... 192 1e-46 gi|169629316|ref|YP_001702965.1| PPE family protein [Mycobacteri... 191 2e-46 gi|308232040|ref|ZP_07414707.2| PPE family protein [Mycobacteriu... 190 4e-46 gi|118616922|ref|YP_905254.1| PPE family protein [Mycobacterium ... 190 5e-46 gi|183980573|ref|YP_001848864.1| PPE family protein, PPE4 [Mycob... 189 7e-46 gi|296167571|ref|ZP_06849908.1| PPE family protein [Mycobacteriu... 189 7e-46 gi|240171483|ref|ZP_04750142.1| PPE-family protein [Mycobacteriu... 188 2e-45 gi|145220929|ref|YP_001131607.1| PPE protein [Mycobacterium gilv... 184 2e-44 gi|169631856|ref|YP_001705505.1| PPE family protein [Mycobacteri... 184 2e-44 gi|308376353|ref|ZP_07438549.2| putative PPE family protein [Myc... 184 2e-44 gi|167967058|ref|ZP_02549335.1| PPE family protein [Mycobacteriu... 184 3e-44 gi|315442101|ref|YP_004074980.1| PPE-repeat containing protein [... 184 3e-44 gi|298523757|ref|ZP_07011166.1| ppe family protein [Mycobacteriu... 184 3e-44 gi|307078212|ref|ZP_07487382.1| putative PPE family protein [Myc... 184 3e-44 >gi|15839476|ref|NP_334513.1| PPE family protein [Mycobacterium tuberculosis CDC1551] gi|57116689|ref|YP_177690.1| PPE family protein [Mycobacterium tuberculosis H37Rv] gi|148659858|ref|YP_001281381.1| PPE family protein [Mycobacterium tuberculosis H37Ra] 48 more sequence titles Length=463 Score = 908 bits (2347), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/463 (100%), Positives = 463/463 (100%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD Sbjct 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY Sbjct 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 >gi|254366552|ref|ZP_04982596.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem] gi|134152064|gb|EBA44109.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem] Length=463 Score = 905 bits (2340), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/463 (99%), Positives = 462/463 (99%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAA VAVPSTQPAPPIRAPGGDAAD Sbjct 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAAMVAVPSTQPAPPIRAPGGDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY Sbjct 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 >gi|289572676|ref|ZP_06452903.1| PPE family protein [Mycobacterium tuberculosis K85] gi|289537107|gb|EFD41685.1| PPE family protein [Mycobacterium tuberculosis K85] Length=463 Score = 905 bits (2340), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/463 (99%), Positives = 462/463 (99%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD Sbjct 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY Sbjct 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLP TWTTDAEQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPITWTTDAEQ 463 >gi|289747863|ref|ZP_06507241.1| PPE family protein [Mycobacterium tuberculosis 02_1987] gi|289760195|ref|ZP_06519573.1| PPE family protein [Mycobacterium tuberculosis T85] gi|298527487|ref|ZP_07014896.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A] 6 more sequence titles Length=463 Score = 905 bits (2340), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/463 (99%), Positives = 462/463 (99%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADY RMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD Sbjct 121 NFFGINTVPIALNEADYARMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY Sbjct 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 >gi|289441465|ref|ZP_06431209.1| PPE family protein [Mycobacterium tuberculosis T46] gi|289567988|ref|ZP_06448215.1| PPE family protein [Mycobacterium tuberculosis T17] gi|289748566|ref|ZP_06507944.1| PPE family protein [Mycobacterium tuberculosis T92] gi|289414384|gb|EFD11624.1| PPE family protein [Mycobacterium tuberculosis T46] gi|289541741|gb|EFD45390.1| PPE family protein [Mycobacterium tuberculosis T17] gi|289689153|gb|EFD56582.1| PPE family protein [Mycobacterium tuberculosis T92] Length=463 Score = 904 bits (2337), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/463 (99%), Positives = 462/463 (99%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD Sbjct 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY Sbjct 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHL NLPPAGLLPIAAALGPGDQWGANLAVAVTPAT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLPNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 >gi|31791274|ref|NP_853767.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|121636009|ref|YP_976232.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988482|ref|YP_002643169.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] gi|31616859|emb|CAD92961.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97] gi|121491656|emb|CAL70114.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224771595|dbj|BAH24401.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] gi|341600025|emb|CCC62693.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ] Length=463 Score = 903 bits (2334), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/463 (99%), Positives = 462/463 (99%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD Sbjct 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 T LDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY Sbjct 181 TWLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 >gi|167968254|ref|ZP_02550531.1| PPE family protein [Mycobacterium tuberculosis H37Ra] gi|254549030|ref|ZP_05139477.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|297632569|ref|ZP_06950349.1| PPE family protein [Mycobacterium tuberculosis KZN 4207] gi|297729543|ref|ZP_06958661.1| PPE family protein [Mycobacterium tuberculosis KZN R506] Length=457 Score = 894 bits (2309), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/457 (99%), Positives = 457/457 (100%), Gaps = 0/457 (0%) Query 7 VHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAATQYVAAH 66 +HSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAATQYVAAH Sbjct 1 MHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAATQYVAAH 60 Query 67 GPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIATNFFGIN 126 GPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIATNFFGIN Sbjct 61 GPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIATNFFGIN 120 Query 127 TVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAADTRLDVL 186 TVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAADTRLDVL Sbjct 121 TVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAADTRLDVL 180 Query 187 SSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLL 246 SSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLL Sbjct 181 SSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLL 240 Query 247 LLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGG 306 LLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGG Sbjct 241 LLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGG 300 Query 307 SPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAG 366 SPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAG Sbjct 301 SPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAG 360 Query 367 AARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAG 426 AARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAG Sbjct 361 AARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAG 420 Query 427 TAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 421 TAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 457 >gi|340625132|ref|YP_004743584.1| PPE family protein [Mycobacterium canettii CIPT 140010059] gi|340003322|emb|CCC42440.1| PPE family protein [Mycobacterium canettii CIPT 140010059] Length=463 Score = 799 bits (2064), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/463 (98%), Positives = 455/463 (99%), Gaps = 0/463 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYA ACAEL QL+ EVQASSWQGT AT Sbjct 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYARACAELSQLMVEVQASSWQGTGAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT Sbjct 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPG DAAD Sbjct 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGRDAAD 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 TRL+VLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPA+TVVLALVALQLYDFLWYPYY Sbjct 181 TRLNVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAITVVLALVALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVT AT Sbjct 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTSAT 300 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 AAVPGGSPPTSNPAPAAPSSNSVGSASA PGISYAVPGLAPPGVSSGPKAGTKSPD+AAD Sbjct 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAPPGISYAVPGLAPPGVSSGPKAGTKSPDSAAD 360 Query 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG Sbjct 361 TLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAG 420 Query 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTD EQ Sbjct 421 TLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDTEQ 463 >gi|294992941|ref|ZP_06798632.1| PPE family protein [Mycobacterium tuberculosis 210] Length=274 Score = 534 bits (1375), Expect = 1e-149, Method: Compositional matrix adjust. Identities = 274/274 (100%), Positives = 274/274 (100%), Gaps = 0/274 (0%) Query 190 GQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLLLLP 249 GQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLLLLP Sbjct 1 GQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLLLLP 60 Query 250 FFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGGSPP 309 FFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGGSPP Sbjct 61 FFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGGSPP 120 Query 310 TSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAAR 369 TSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAAR Sbjct 121 TSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAAR 180 Query 370 PGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAP 429 PGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAP Sbjct 181 PGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAP 240 Query 430 TTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 TTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ Sbjct 241 TTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 274 >gi|15828079|ref|NP_302342.1| PPE-family protein [Mycobacterium leprae TN] gi|221230556|ref|YP_002503972.1| PPE-family protein [Mycobacterium leprae Br4923] gi|13093633|emb|CAC30946.1| PPE-family protein [Mycobacterium leprae] gi|219933663|emb|CAR72088.1| PPE-family protein [Mycobacterium leprae Br4923] Length=468 Score = 499 bits (1285), Expect = 4e-139, Method: Compositional matrix adjust. Identities = 271/469 (58%), Positives = 326/469 (70%), Gaps = 12/469 (2%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHS LLSAG G SLLVAA QWQELS QY A AEL +LL VQA+SW+GT+AT Sbjct 1 MAIPPEVHSVLLSAGQGAESLLVAATQWQELSKQYTYAAAELTRLLTHVQATSWRGTSAT 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++VAAHG YL WLEQT+IN+A+TA QH AA AY SALAAMPT AEL AN A G LIAT Sbjct 61 RFVAAHGAYLVWLEQTSINNAITAKQHEIAAIAYSSALAAMPTLAELTANRATRGFLIAT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PIALNEADYVRMW+QAADTMA YQA+++A T + TQ APPI APG + Sbjct 121 NFFGINTIPIALNEADYVRMWVQAADTMATYQAISEAVTATILPTQVAPPILAPGSATQN 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 V I QL+ DILDFIA+PYKYFL FF++ GF PA+ VVLA++ALQLYDFLWYPYY Sbjct 181 VLQSVPDWIVQLLTDILDFIADPYKYFLRFFQRLGFRPAIAVVLAIIALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASYG+LLLPFF P LS L LS L + AGL P A P + G + V V P Sbjct 241 ASYGMLLLPFFAPALSVLGTLSVLWN--GQLSAGLPPNPAGSHPDNNAGPRIHVGVAPPA 298 Query 301 AAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAAD 360 +A G+ TSN AP+ +S + + ++P I YA+PGL+PP VSSGPKAGTKSPDTA + Sbjct 299 SATSSGNSYTSNSAPSTSASATTDNPLSSPSIRYAIPGLSPPEVSSGPKAGTKSPDTATN 358 Query 361 TLATAGAARPG--LARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPA----PANAA 414 T+ AAR ARAHR++ +++ G RGYR EF++ TAT+ D P ++ Sbjct 359 TIGITAAARTNSPSARAHRKRGNKTRGGARGYRYEFVEGTATMADTVDAPDHSEPTSHTI 418 Query 415 GSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ 463 + AG +GFAGT PTT+ GM STS++VPLLPTTW T + Sbjct 419 SNHSAGPIGFAGTVPTTASTPTGMAA----STSSSVPLLPTTWITGTSE 463 >gi|118619893|ref|YP_908225.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118572003|gb|ABL06754.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=472 Score = 494 bits (1272), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 302/470 (65%), Positives = 349/470 (75%), Gaps = 12/470 (2%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHS LLSAG GPGSLL AA QWQELS QY+ A EL QLL EVQA+SWQG AA Sbjct 1 MAIPPEVHSALLSAGQGPGSLLAAAAQWQELSAQYSAAVVELTQLLAEVQATSWQGYAAH 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Q++AAHGPYL WLEQ AI+S+VTAAQH AAA Y SA+AAMPT AELAANHAIHGVL+ T Sbjct 61 QWLAAHGPYLIWLEQAAIDSSVTAAQHRIAAAGYSSAVAAMPTLAELAANHAIHGVLVVT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGIN +PIALNEADYVRMW+QAA+TM YQAV++ A AVP T PAP I PGG + Sbjct 121 NFFGINAIPIALNEADYVRMWVQAAETMTTYQAVSEVAAAAVPPTPPAPSILRPGGGSQA 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 + S IGQL+RDIL F+A+PYKYFLEFF++ GFSPAV V+LA++ALQLYDFLWYPYY Sbjct 181 AASGIGSWIGQLLRDILSFLADPYKYFLEFFQRMGFSPAVAVILAIIALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLA-----VA 295 ASYGLLLLPFFTP LSAL+ LSAL +L N P P+AA P ++ A+LA V Sbjct 241 ASYGLLLLPFFTPALSALSVLSALAYLANRTPI-TAPVAA---PAERSVADLAGPQPVVG 296 Query 296 VTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSP 355 +TPA +A SP ++PAP+APS GS ++P ISYAV G APPGVSSGP A T + Sbjct 297 LTPAASAFAPPSPQATSPAPSAPSPAPTGSPPSSPAISYAVLGPAPPGVSSGPGATTGAA 356 Query 356 DTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPA---PAN 412 TA DT A A +RA RRKRS++ VG+RGYRDEFL AT+D+ D P PA Sbjct 357 ATATDTTRPAAPAALSSSRAGRRKRSKNRVGVRGYRDEFLQEPATMDSPIDAPGTAEPAP 416 Query 413 AAGSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAE 462 + SQGAG LG GTA + GAAAGMV+LSSH TST VPLLP TWT D+E Sbjct 417 SPSSQGAGPLGLTGTAASHDGAAAGMVRLSSHGTSTAVPLLPATWTNDSE 466 >gi|183980293|ref|YP_001848584.1| PPE family protein, PPE1 [Mycobacterium marinum M] gi|183173619|gb|ACC38729.1| PPE family protein, PPE1 [Mycobacterium marinum M] Length=472 Score = 467 bits (1201), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 303/470 (65%), Positives = 352/470 (75%), Gaps = 12/470 (2%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHS LLSAG GPGSLL AA QWQELS QY+ A EL QLL EVQA+SWQG AA Sbjct 1 MAIPPEVHSALLSAGQGPGSLLAAAAQWQELSAQYSAAVVELTQLLAEVQATSWQGYAAH 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 Q++AAHGPYL WLEQ AI+S+VTAAQH AAA Y SA+AAMPT AELAANHAIHGVL+ T Sbjct 61 QWLAAHGPYLIWLEQAAIDSSVTAAQHRIAAAGYSSAVAAMPTLAELAANHAIHGVLVVT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGIN +PIALNEADYVRMW+QAA+TM YQAV++ A AVP T PAP I PGG++ Sbjct 121 NFFGINAIPIALNEADYVRMWIQAAETMTTYQAVSEVAAAAVPPTPPAPSILRPGGESQA 180 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 + S IGQL+RDIL F+A+PYKYFLEFF++ GFSPAV V+LA++ALQLYDFLWYPYY Sbjct 181 AASGIGSWIGQLLRDILSFLADPYKYFLEFFQRMGFSPAVAVILAIIALQLYDFLWYPYY 240 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLA-----VA 295 ASYGLLLLPFFTP LSAL+ALSAL +L N P P+AA P ++ A+LA V Sbjct 241 ASYGLLLLPFFTPALSALSALSALAYLANRTPI-TAPVAA---PAERSVADLAGPQPVVG 296 Query 296 VTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSP 355 +TPA +A SP ++PAP+APS GS ++P ISYAV G APPGVSSGP+A T + Sbjct 297 LTPAASAFAPPSPQATSPAPSAPSPAPTGSPPSSPAISYAVLGPAPPGVSSGPRATTGAA 356 Query 356 DTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPA---PAN 412 TA DT A A +RA RRKRS++ VG+RGYRDEFL AT+D+ D P PA Sbjct 357 ATATDTTRAAAPAALSSSRASRRKRSKNRVGVRGYRDEFLQEPATMDSPIDAPGTAEPAP 416 Query 413 AAGSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAE 462 + SQGAG LG GTA + GAAAGMV+LSSH TST VPLLP TWT D+E Sbjct 417 SPSSQGAGPLGLTGTAASHDGAAAGMVRLSSHGTSTAVPLLPATWTNDSE 466 >gi|559908|emb|CAA86359.1| unknown [Mycobacterium leprae] Length=438 Score = 369 bits (947), Expect = 7e-100, Method: Compositional matrix adjust. Identities = 184/264 (70%), Positives = 208/264 (79%), Gaps = 0/264 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MAIPPEVHS LLSAG G SLLVAA QWQELS QY A AEL +LL VQA+SW+GT+AT Sbjct 22 MAIPPEVHSVLLSAGQGAESLLVAATQWQELSKQYTYAAAELTRLLTHVQATSWRGTSAT 81 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++VAAHG YL WLEQT+IN+A+TA QH AA AY SALAAMPT AEL AN A G LIAT Sbjct 82 RFVAAHGAYLVWLEQTSINNAITAKQHEIAAIAYSSALAAMPTLAELTANRATRGFLIAT 141 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PIALNEADYVRMW+QAADTMA YQA+++A T + TQ APPI APG + Sbjct 142 NFFGINTIPIALNEADYVRMWVQAADTMATYQAISEAVTATILPTQVAPPILAPGSATQN 201 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 V I QL+ DILDFIA+PYKYFL FF++ GF PA+ VVLA++ALQLYDFLWYPYY Sbjct 202 VLQSVPDWIVQLLTDILDFIADPYKYFLRFFQRLGFRPAIAVVLAIIALQLYDFLWYPYY 261 Query 241 ASYGLLLLPFFTPTLSALTALSAL 264 ASYG+LLLPFF P LS L LS L Sbjct 262 ASYGMLLLPFFAPALSVLGTLSVL 285 >gi|169627772|ref|YP_001701421.1| PPE-family protein [Mycobacterium abscessus ATCC 19977] gi|169239739|emb|CAM60767.1| Hypothetical PPE-family protein [Mycobacterium abscessus] Length=468 Score = 358 bits (919), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 245/476 (52%), Positives = 302/476 (64%), Gaps = 35/476 (7%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG++L AA QWQE+ + YA EL Q+L V+A SWQG +A+ Sbjct 7 MAEPPEVHSALLSAGPGPGAVLAAAVQWQEIGNNYANTAVELAQVLAGVRAGSWQGPSAS 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 +YVAAH PYLAWLEQ A S+V AAQH AAAY SALAAMPT AELAANH HGVL+ T Sbjct 67 EYVAAHLPYLAWLEQAAAESSVIAAQHETTAAAYNSALAAMPTLAELAANHITHGVLVGT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PIALNEADYVRMW+QAA TM+AYQA +A T A+P TQ P I +PGG+A Sbjct 127 NFFGINTIPIALNEADYVRMWVQAAATMSAYQATTEAMTSAIPPTQQPPAILSPGGEARS 186 Query 181 TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYY 240 + DV S Q+++ + + F ++FE+ GF+PA + VLA++ L LYD LWYPYY Sbjct 187 DQSDVPGSPDQIMKML--------QGFQQWFEKMGFNPATSAVLAVIMLFLYDLLWYPYY 238 Query 241 ASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPAT 300 ASY LLPF P LS L+ L+AL+HL A AAAL PGD+ V P Sbjct 239 ASY---LLPFLIPALSGLSGLAALMHLRPA--APGPVPAAALSPGDRPIRRPTQHVEPNL 293 Query 301 AAVP----------GGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKA 350 AA+P G S P S P A + +SV + SAA ISYA+PGL PPGVS GPK+ Sbjct 294 AALPLPTSSVVPSGGSSVPVSTPTAPAHTVSSVPAPSAA--ISYAIPGLVPPGVSFGPKS 351 Query 351 GTKSPDTAADTLATAGAARPGLARA-----HRRKRSESGVGIRGYRDEFLDATATVDAAT 405 KS ++A DT+A AAR +A + ++E+G G R E+L+ TA + A Sbjct 352 TEKSSESAVDTVAAVAAARGAVAAQARRRLRGKNKAEAG----GRRHEYLEETAGMGATA 407 Query 406 DVPAPANAAGSQGAGTLGFAGTAP-TTSGAAAGMVQLSSHSTSTTVPLLPTTWTTD 460 PA AA +G G LGFAGTAP S A V+LSS +P+LP+TW D Sbjct 408 TADVPAYAATGRGTGPLGFAGTAPAAASTHVAATVRLSSDEARQVIPMLPSTWDAD 463 >gi|169629340|ref|YP_001702989.1| PPE family protein [Mycobacterium abscessus ATCC 19977] gi|169241307|emb|CAM62335.1| PPE family protein [Mycobacterium abscessus] Length=503 Score = 222 bits (565), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 198/512 (39%), Positives = 266/512 (52%), Gaps = 67/512 (13%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LL AG GPG LL AA QW LS +Y++A EL QLLG A WQG++AT Sbjct 7 MAFPPEVHSALLGAGPGPGPLLAAAAQWHALSYEYSMAATELTQLLGVTAAGVWQGSSAT 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVA+H PYLAWL Q + SA AA H +AAAY +ALAAMPT ELA NH +HG+L+ T Sbjct 67 QYVASHTPYLAWLTQQSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVHGILVGT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PIALNEADYVRMW+QAA TM YQ V+ A A T +P I PG + + Sbjct 127 NFFGINTIPIALNEADYVRMWVQAATTMGVYQGVSSTAVAAAAPTTTSPLIMPPGSELSR 186 Query 181 TRLDV---------------LSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPA------ 219 D+ L S +I +L+F +P + E F +P Sbjct 187 MAADMSGFAAQAQATESGSALDSSNSVIDQLLNFFRDPLGTLRQIIEDFIRNPGAALATW 246 Query 220 --VTVVLALVALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLP 277 +VLA + L+ +++ ++A+ LL P + P L L+A +L PPA Sbjct 247 LPFLLVLASMTYVLFAQVFWLFWAA--LLSAPLWLP----LLILAAWQYL--QPPA---- 294 Query 278 IAAALGPGDQWGANLAVAVT---------PATAAVPGGSPPTSNPAPAAPSSNSVGSASA 328 + AA P D+ L V PA A P +P + A A + + +A Sbjct 295 VDAA--PADEIRPELGSTVNGQREHIEPLPAIALAPTATPVPTASASAPSAPAPAPAPTA 352 Query 329 -----APGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSES 383 AP + A+P PP + GP + A + AA A A R R + Sbjct 353 AGAGFAPYLVGAIPD-EPPAIQFGPTLNEG--NKAQAPASGISAAAAAAASARSRARRKR 409 Query 384 GVGIRGYRDEFLDATATVDAATDVPAPANA-----AGSQGAGTLGFAGTAPTTSGAAAGM 438 G ++ +++D TVDA P P +A A ++GAG LG AGT+P T+ AAG+ Sbjct 410 GARVKDPAPQYMDMNVTVDADYGEP-PGSAQRQSTASARGAGHLGLAGTSPKTTATAAGL 468 Query 439 VQLSSHSTST-------TVPLLPTTWTTDAEQ 463 V S + T VP++PTTW+TD+++ Sbjct 469 VARGSAGSDTDVPETARIVPMIPTTWSTDSDE 500 >gi|342859230|ref|ZP_08715884.1| hypothetical protein MCOL_10138 [Mycobacterium colombiense CECT 3035] gi|342133471|gb|EGT86674.1| hypothetical protein MCOL_10138 [Mycobacterium colombiense CECT 3035] Length=488 Score = 212 bits (539), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 131/247 (54%), Positives = 155/247 (63%), Gaps = 20/247 (8%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG LL AA W LS QYA A AEL LLGE QA +W+G +A Sbjct 1 MASPPEVHSALLSAGPGPGPLLAAAGAWTSLSTQYASAAAELSGLLGEAQAGAWEGPSAE 60 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PYLAWL+Q +++SA AAQ AA AY +ALAAMPT AELA NH +H VL+ T Sbjct 61 QYVAAHLPYLAWLQQASVDSAGAAAQQEVAATAYTAALAAMPTLAELATNHTVHAVLVGT 120 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PIA+NEADY RMW+QAA TM YQAV+ +A A P T AP I PGG Sbjct 121 NFFGINTIPIAVNEADYARMWVQAATTMGTYQAVSGSALAAAPRTMAAPAIVNPGG---- 176 Query 181 TRLDVLSS--------------IGQLIRDILDFIANPYKYFLEFFEQF-GFSPAVTVVLA 225 +++ L+S I QL + DF N + FF F A +L Sbjct 177 -QINSLASNATQNSPGDWWQNFIQQLSKFFQDFFQNIQQMLQNFFSNLPAFLAANGPLLF 235 Query 226 LVALQLY 232 VA Q++ Sbjct 236 FVAYQVF 242 >gi|240168498|ref|ZP_04747157.1| PPE family protein, PPE4 [Mycobacterium kansasii ATCC 12478] Length=420 Score = 209 bits (532), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 119/215 (56%), Positives = 142/215 (67%), Gaps = 10/215 (4%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 +A PPEVHS LLS+G GPG LLVAA W +S +YA EL LLG VQ +W+G +A Sbjct 7 IASPPEVHSSLLSSGPGPGPLLVAAASWTSISAEYASVAEELTALLGGVQIGAWRGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 + AAH PYLAWL + + +SA AAQH AA AY ALAAMPT ELAANHA+H VL+AT Sbjct 67 VFAAAHVPYLAWLLRASADSAGVAAQHEVAATAYTGALAAMPTLPELAANHAVHAVLLAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPG----G 176 NFFGINT+PIALNE DY+RMW+QAA M+ Y A D A +VP PAPP+ PG G Sbjct 127 NFFGINTIPIALNEGDYLRMWIQAATAMSIYHAAVDTALASVPHATPAPPLVKPGVGSAG 186 Query 177 DAADTRLDVLSSIG----QLIRDILDFIANPYKYF 207 DAA T V S++G LI +L +A Y F Sbjct 187 DAAAT--SVQSAVGDIPWNLIWALLKEVAEAYLAF 219 >gi|240172392|ref|ZP_04751051.1| PPE protein [Mycobacterium kansasii ATCC 12478] Length=513 Score = 206 bits (524), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 116/228 (51%), Positives = 149/228 (66%), Gaps = 15/228 (6%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA+PPEVHS LS+G GPG+ L AA +Q LS +Y A EL +L VQ SWQG A Sbjct 10 MALPPEVHSAQLSSGPGPGAFLAAAGAYQVLSAEYGSAVGELAAVLNAVQGGSWQGPTAE 69 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 +YVAAH PYL WLEQ S QH AA AY +ALA+MPT AELAANH +HGVL+AT Sbjct 70 EYVAAHAPYLVWLEQARGKSIAAGLQHQLAAQAYTAALASMPTLAELAANHVVHGVLVAT 129 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPP-IRAPGGDAA 179 NFFGINT+PIALNEADY RMW+QAA TM+ YQAV++ A +VP+T PAPP ++A DAA Sbjct 130 NFFGINTIPIALNEADYFRMWVQAATTMSIYQAVSNVAADSVPATSPAPPLLKADTSDAA 189 Query 180 D--------------TRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQ 213 D +L++ + QL++ ++++ Y ++F + Sbjct 190 DPAQLTALASATDAGNQLNLADLVSQLLQAYINYVEQLYAPIIDFLQD 237 >gi|333988934|ref|YP_004521548.1| PPE family protein [Mycobacterium sp. JDM601] gi|333484902|gb|AEF34294.1| PPE family protein [Mycobacterium sp. JDM601] Length=465 Score = 205 bits (522), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 184/480 (39%), Positives = 246/480 (52%), Gaps = 58/480 (12%) Query 11 LLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAATQYVAAHGPYL 70 +LS+G GPG LL AA W LS +YA EL LLG VQ+ +WQG +A QY+AAH PYL Sbjct 1 MLSSGPGPGPLLSAAGAWNALSVEYASVADELTALLGAVQSGAWQGPSAEQYLAAHVPYL 60 Query 71 AWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIATNFFGINTVPI 130 AWL + + +SA AAQH AA+AY SALA MPT AELAANH HGVL+ATNFFGINT+PI Sbjct 61 AWLGKASADSAGVAAQHEVAASAYASALATMPTLAELAANHMTHGVLVATNFFGINTIPI 120 Query 131 ALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAADTRLDVLSSIG 190 ALNEADY RMW+QAA TM+ Y AV+ AA + P T APP+ D A D S IG Sbjct 121 ALNEADYARMWVQAATTMSTYHAVSGAALASAPRTVQAPPMLK--ADTAQPAADTSSDIG 178 Query 191 QLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYP--YYASYGLLLL 248 DF + ++FF + V+ +++ W+P ++ +Y + Sbjct 179 -------DFFTRLWDQLVQFFTD-----PIGVIREILSSPGALVTWFPLLFFIAYEAFFI 226 Query 249 PFFTPTLSALTALSALI---------HLLNL------PPAGLLPIAAALGP-GDQWGANL 292 PF S L A +AL+ HL ++ P L P+ A+ P GD+ Sbjct 227 PFGWTFWSLLFASAALVPILLGVGLGHLADMLGGELAPDGDLKPVPVAVAPSGDR----- 281 Query 293 AVAVTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAP-------GISYAVPGLAPPGVS 345 AT V G SP + P A+ ++ A+A G Y V G PG Sbjct 282 ------ATPVVAGFSPSVATPGAASVTAAPATPAAAPAPAAGGAIGFGYLVAG-GDPGTG 334 Query 346 SGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSESGVGI-RGYRDEFLDATATVDAA 404 GP ++ A + A AA G + R + + + DE++D + A Sbjct 335 LGPTLTERNKAQAPASRVPAAAAAVGASARERSRARRRRRAVLHDHADEYMDMDS--GPA 392 Query 405 TDVPAPANAAGS-QGAGTLGFAGT-APTTSGAAAGMVQLS--SHSTSTTVPLLPTTWTTD 460 V PA+AAGS +GAG LGF GT + AA+G+ L+ VP+LP TW+ + Sbjct 393 GPVDEPASAAGSDRGAGALGFTGTVGGRGTAAASGLTTLAGDGFGGGPGVPMLPETWSEN 452 >gi|296167589|ref|ZP_06849914.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897132|gb|EFG76743.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=311 Score = 205 bits (522), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 130/242 (54%), Positives = 161/242 (67%), Gaps = 10/242 (4%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG LL AA W LS +YA A AEL +LGE QA +WQG Sbjct 7 MASPPEVHSTLLSAGPGPGPLLAAAGAWTSLSAEYATAAAELTGVLGETQAGAWQGPTGA 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QY+AAH PYLAWL+Q + +SA AAQH AAAAY +ALAAMPT ELAANHA+HGVL+AT Sbjct 67 QYLAAHVPYLAWLQQASADSAGVAAQHEVAAAAYTAALAAMPTLGELAANHAVHGVLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDA-- 178 NFFG+NT+PIA+NEADY RMW+QAA M AYQA + AA + P + PAP I PGGDA Sbjct 127 NFFGVNTIPIAVNEADYARMWVQAATVMGAYQATSGAALASAPRSTPAPSIVRPGGDANT 186 Query 179 --ADTRLDVLSSIGQ-LIRDILDFIANPYKYFLEFFEQF-----GFSPAVTVVLALVALQ 230 A+T + + Q LI+ + F+ + ++ + + F F A +L VA Q Sbjct 187 LSANTAQNTPGNWWQNLIQQLSKFLQDFFQNIQQMLQNFSANLPAFLAANGPLLFFVAYQ 246 Query 231 LY 232 ++ Sbjct 247 VF 248 >gi|183980812|ref|YP_001849103.1| PPE family protein [Mycobacterium marinum M] gi|183174138|gb|ACC39248.1| PPE family protein [Mycobacterium marinum M] Length=412 Score = 204 bits (518), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 106/171 (62%), Positives = 122/171 (72%), Gaps = 0/171 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG L AA W L ++ A EL LLG VQA++WQGT+A Sbjct 7 MASPPEVHSALLSAGPGPGPLHEAATAWTALCAEHTSAAEELTTLLGGVQAAAWQGTSAQ 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YV AH PYLAWL T+ + A TAA+H AA AY SALAAMPT AEL ANH H L+AT Sbjct 67 SYVDAHAPYLAWLTTTSADYAATAAEHEVAAGAYTSALAAMPTLAELTANHTTHTALVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI 171 NFFG+NT+PI LNEADY RMW+QAA TM+AYQ V+ ++P T PAPPI Sbjct 127 NFFGLNTIPITLNEADYARMWVQAATTMSAYQVVSGTTLASMPHTTPAPPI 177 >gi|169627152|ref|YP_001700801.1| PPE family protein [Mycobacterium abscessus ATCC 19977] gi|169239119|emb|CAM60147.1| Probable PPE family protein [Mycobacterium abscessus] Length=510 Score = 203 bits (517), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 146/305 (48%), Positives = 181/305 (60%), Gaps = 29/305 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG+LL AA QWQ LS QYA A EL +LLG A SWQG +A Sbjct 7 MASPPEVHSALLSAGPGPGALLAAAAQWQALSTQYATAATELTELLGSTVAGSWQGPSAM 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QY A+H PYLAWL Q + SA A H +AAAY +ALAAMPT AELAANH IHGVL+AT Sbjct 67 QYAASHAPYLAWLTQQSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIHGVLLAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PIALNEADY+RMW+QAA TM YQ V+ AA A TQP+P I APGG+ + Sbjct 127 NFFGINTIPIALNEADYIRMWIQAATTMGVYQGVSSAALAATTPTQPSPMIMAPGGEMSR 186 Query 181 TRLDVLS---------------SIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLA 225 D++S S ++ ++ F+ NP + E F +P Sbjct 187 MSADMMSMAAQPQAAESGSALDSSNNIMDQLMRFMTNPLGTLQDMIEDFMRNPVAAF--- 243 Query 226 LVALQLYDFLWYP--YYASYGLLLLPF-FTPTLSALTALSALIHLLNLPPAGLLPIAAAL 282 F W+P ++ +Y +PF FT L+A + L +L L + L+P A Sbjct 244 --------FAWFPLLFFIAYEAFFIPFGFTFWGVLLSAPAWLPIVLGLALSALVPPAGIE 295 Query 283 GPGDQ 287 PG + Sbjct 296 EPGQE 300 >gi|183983621|ref|YP_001851912.1| PPE family protein [Mycobacterium marinum M] gi|183176947|gb|ACC42057.1| PPE family protein [Mycobacterium marinum M] Length=453 Score = 199 bits (506), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 112/219 (52%), Positives = 138/219 (64%), Gaps = 6/219 (2%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG L AA W LS ++A EL LLG A++W+GT+A Sbjct 7 MASPPEVHSALLSAGPGPGPLYEAATAWTALSAEHASVAEELTTLLGGA-AATWEGTSAQ 65 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YV AH PYLAWL T+ + A TAA+H AA AY SALA MPT AELA NH H L+AT Sbjct 66 SYVDAHAPYLAWLTTTSADYAATAAEHEVAAGAYTSALATMPTLAELAVNHTTHTALVAT 125 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI-RAPGGDAA 179 NFFG+NT+PI LNEADY RMW+QAA TM+AYQ ++ ++P T PAPP+ +A G A Sbjct 126 NFFGLNTIPITLNEADYARMWIQAATTMSAYQVISGTTLASMPHTTPAPPVLKAEIGTLA 185 Query 180 DTRLDVLSS----IGQLIRDILDFIANPYKYFLEFFEQF 214 D L + + I I+ FIA ++ F + Sbjct 186 GALSDALVPAPLFLWETILAIIAFIAKLAEFIYLFVSEL 224 >gi|340625294|ref|YP_004743746.1| PPE family protein [Mycobacterium canettii CIPT 140010059] gi|340003484|emb|CCC42604.1| PPE family protein [Mycobacterium canettii CIPT 140010059] Length=556 Score = 199 bits (505), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 121/219 (56%), Positives = 143/219 (66%), Gaps = 3/219 (1%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS+G GPG LLV+A+ W LS YA EL LL VQA +W G A Sbjct 7 MASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAETADELAALLAAVQAGTWDGPTAA 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PYLAWL Q + NSA A + AA AY +ALAAMPT AEL ANHA+HGVL+AT Sbjct 67 VYVAAHTPYLAWLVQASANSAAMATRQETAATAYGTALAAMPTLAELGANHALHGVLMAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI-RAPGGDAA 179 NFFGINT+PIALNE+DY RMW+QAA TMA+YQAV+ AA A P T PAP I +A AA Sbjct 127 NFFGINTIPIALNESDYARMWIQAATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAA 186 Query 180 DTRLDVLSSIGQLIRDI--LDFIANPYKYFLEFFEQFGF 216 + + Q ++ I DF N + F+ + F Sbjct 187 SDEPNQVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPF 225 Score = 43.5 bits (101), Expect = 0.073, Method: Compositional matrix adjust. Identities = 43/122 (36%), Positives = 56/122 (46%), Gaps = 16/122 (13%) Query 344 VSSGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDA 403 V +G + T PD A A A + RR+R + RGY E+LD Sbjct 442 VGTGVRKKTPEPDNAEAPAAAAAPEEQ--VQPQRRRRPKIKQLGRGY--EYLD------- 490 Query 404 ATDVPAPANAAGS-QGAGTLGFAGTAPTTS-GAAAGMVQL--SSHSTSTTVPLLPTTWTT 459 D + GS QGAGTLGFAGT S G AG++ L + S P++P TW T Sbjct 491 -LDPETGHDPTGSPQGAGTLGFAGTTHKASPGQVAGLITLPNDAFGGSPRTPMMPGTWDT 549 Query 460 DA 461 D+ Sbjct 550 DS 551 >gi|323717087|gb|EGB26297.1| PPE family protein [Mycobacterium tuberculosis CDC1551A] Length=403 Score = 198 bits (504), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 122/223 (55%), Positives = 145/223 (66%), Gaps = 3/223 (1%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS+G GPG LLV+A+ W LS YA EL LL VQA +W G A Sbjct 7 MASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAETADELAALLAAVQAGTWDGPTAA 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PYLAWL Q + NSA A + AA AY +ALAAMPT AEL ANHA+HGVL+AT Sbjct 67 VYVAAHTPYLAWLVQASANSAAMATRQETAATAYGTALAAMPTLAELGANHALHGVLMAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI-RAPGGDAA 179 NFFGINT+PIALNE+DY RMW+QAA TMA+YQAV+ AA A P T PAP I +A AA Sbjct 127 NFFGINTIPIALNESDYARMWIQAATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAA 186 Query 180 DTRLDVLSSIGQLIRDI--LDFIANPYKYFLEFFEQFGFSPAV 220 + + Q ++ I DF N + F+ + F A+ Sbjct 187 SDEPNQVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPFLQAM 229 >gi|339296965|gb|AEJ49075.1| PPE family protein [Mycobacterium tuberculosis CCDC5180] Length=241 Score = 198 bits (504), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 121/219 (56%), Positives = 143/219 (66%), Gaps = 3/219 (1%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS+G GPG LLV+A+ W LS YA EL LL VQA +W G A Sbjct 7 MASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAETADELAALLAAVQAGTWDGPTAA 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PYLAWL Q + NSA A + AA AY +ALAAMPT AEL ANHA+HGVL+AT Sbjct 67 VYVAAHTPYLAWLVQASANSAAMATRQETAATAYGTALAAMPTLAELGANHALHGVLMAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI-RAPGGDAA 179 NFFGINT+PIALNE+DY RMW+QAA TMA+YQAV+ AA A P T PAP I +A AA Sbjct 127 NFFGINTIPIALNESDYARMWIQAATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAA 186 Query 180 DTRLDVLSSIGQLIRDI--LDFIANPYKYFLEFFEQFGF 216 + + Q ++ I DF N + F+ + F Sbjct 187 SDEPNQVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPF 225 >gi|183983105|ref|YP_001851396.1| PPE family protein, PPE37 [Mycobacterium marinum M] gi|183176431|gb|ACC41541.1| PPE family protein, PPE37 [Mycobacterium marinum M] Length=479 Score = 197 bits (501), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 189/494 (39%), Positives = 247/494 (50%), Gaps = 55/494 (11%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A+PPEVHS LLS G GP +L AA W+ L+ QY EL QLL V+A SW G+ A Sbjct 7 FALPPEVHSTLLSTGPGPSALWSAAAAWRALATQYTDISDELTQLLAAVRAGSWDGSTAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++VAAH P+L WL Q A + A H +AAA Y SALAAMPT AELA NHA+HG L+AT Sbjct 67 RFVAAHQPFLDWLAQAAAVANAAATAHESAAAGYTSALAAMPTLAELATNHAVHGALVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIR-APGGDAA 179 NFFGINT+PIA NE+DY+RMW+QAA TM YQAV+ + A P T PAP I A AA Sbjct 127 NFFGINTIPIAFNESDYMRMWVQAAITMTGYQAVSQHSVTATPRTSPAPQIMTADAAPAA 186 Query 180 DTRL-DVLSSIGQLIRDILDFIAN--------PYKYFLEFFEQFGFSPAVTVVLALVALQ 230 + + D + I Q ++ L+F+ N P + F+ S A V VA Sbjct 187 TSSMPDPVKIILQALQGFLNFLRNLAAETLSGPLEKFVVHVLDSFISFASGSVFKFVAYA 246 Query 231 LYDFLWY--PYYASYGLLLLPFFTPTLSALTALSALIHLLNLPP--AGLLPIAAALGPGD 286 + D + Y P+ + L LP T L+ L +S PP A LP A GP + Sbjct 247 VLDPMIYFGPFTPAISPLGLPAVTVGLAGLACIST-------PPQTAPPLPGVAQSGPPN 299 Query 287 QWGANLAVAVT-PATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGIS---YAVPGLAPP 342 ++ A+T A A V G+ A ++ G +SA P + YAV Sbjct 300 H---QISPAITGVAVAGVSSGATVAGATPTAHAAAAPSGPSSAGPVAAQSFYAV------ 350 Query 343 GVSSGPKAGTKSPDTAADTLA-------TAGAARPG-LARAHRRKRSESGVGIRGYRDEF 394 GP G ++P T LA A PG ARA R+ + +R YR EF Sbjct 351 ---LGPDGGGRTPTTNGKALAGATADAVAPAARLPGDQARATSRRARTAQKRLRQYRYEF 407 Query 395 LDATA---TVDAATDVPAPANAAGSQGAGTLGFAGTAPTTSGAAAGMV---QLSSHSTST 448 LDA TVD P +A GA F+ T + + + + +T Sbjct 408 LDADGYPTTVDPPAAEP---SAVSEHGANASEFSREISKTIAGQPDRLTAGRETRFAETT 464 Query 449 TVPLLPTTWTTDAE 462 T+P+LP TW TDA+ Sbjct 465 TLPMLPRTW-TDAD 477 >gi|296165161|ref|ZP_06847709.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899469|gb|EFG78927.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=307 Score = 196 bits (499), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 129/266 (49%), Positives = 156/266 (59%), Gaps = 30/266 (11%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 +A PPEVHS LLS+G GPG LL AA W +S QYA A ELG LLG VQ +W+G A Sbjct 7 IAFPPEVHSTLLSSGPGPGPLLAAAATWSSMSGQYAEAADELGGLLGAVQGGAWEGPTAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PYLAWL +++ SA AA H AA AY +ALAAMPT ELAANHA+H L+AT Sbjct 67 QYVAAHAPYLAWLLESSAKSATAAALHETAAGAYTAALAAMPTMPELAANHAVHAALVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDA-- 178 NFFG+NT+PIA+NEADY RMW+QAA TM +YQ A++A AVP+T PAP I PG +A Sbjct 127 NFFGVNTIPIAVNEADYARMWVQAATTMTSYQVTAESALAAVPATTPAPAIVTPGAEASV 186 Query 179 ----ADTRLDVLSSI----GQLIRDILDFIAN-------------------PYKYFL-EF 210 ADT+ + QL + + N P+ L F Sbjct 187 ATLHADTQQQAAQTYPSWQDQLTAWLQQYTKNFAWPVSKDLNPGGWPFPPVPFVNGLASF 246 Query 211 FEQFGFSPAVTVVLALVALQLYDFLW 236 F Q GFSPA++ L W Sbjct 247 FGQLGFSPALSSALGWAIFHTLMIFW 272 >gi|183984239|ref|YP_001852530.1| PPE family protein [Mycobacterium marinum M] gi|183177565|gb|ACC42675.1| PPE family protein [Mycobacterium marinum M] Length=452 Score = 196 bits (497), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 105/171 (62%), Positives = 121/171 (71%), Gaps = 1/171 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG L AA W LS ++A A AEL LLG A++WQG +A Sbjct 7 MASPPEVHSALLSAGPGPGPLHEAATAWTALSTEHAEAAAELTTLLGGA-AAAWQGPSAQ 65 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YV AH PYLAWL T+ + A TAA+H AA AY SALA MPT AELA NH H L+AT Sbjct 66 SYVDAHAPYLAWLTTTSADYAATAAEHEVAAGAYTSALATMPTLAELAVNHTTHTALVAT 125 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI 171 NFFG+NT+PI LNEADY RMW+QAA TM+AYQ V+ ++P T PAPPI Sbjct 126 NFFGLNTIPITLNEADYARMWIQAATTMSAYQVVSGTTLASMPHTTPAPPI 176 >gi|289748258|ref|ZP_06507636.1| PPE family protein [Mycobacterium tuberculosis T92] gi|289688845|gb|EFD56274.1| PPE family protein [Mycobacterium tuberculosis T92] Length=410 Score = 196 bits (497), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 101/169 (60%), Positives = 118/169 (70%), Gaps = 0/169 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A PPEVHS LLSAG GP SL AA +W LS +YA A EL +L VQ +W+G +A Sbjct 7 FASPPEVHSALLSAGPGPASLQAAAAEWTSLSAEYASAAQELTAVLAAVQGGAWEGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PYLAWL +++ +SA A QH AY SALAAMPT ELAANH H VL+ T Sbjct 67 AYVAAHLPYLAWLTKSSADSARLATQHEVMTTAYASALAAMPTLTELAANHTSHAVLLGT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAP 169 NFFGINT+PIALNEADY RMW+QAA TM+ Y+ +DAA + P T PAP Sbjct 127 NFFGINTIPIALNEADYARMWIQAATTMSIYEGTSDAALASAPQTTPAP 175 >gi|31793303|ref|NP_855796.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|121638005|ref|YP_978229.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990499|ref|YP_002645186.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] gi|31618895|emb|CAD97000.1| conserved hypothetical protein, PPE [Mycobacterium bovis AF2122/97] gi|121493653|emb|CAL72128.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773612|dbj|BAH26418.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] gi|341602043|emb|CCC64717.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ] Length=464 Score = 195 bits (496), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 186/486 (39%), Positives = 241/486 (50%), Gaps = 61/486 (12%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A+PPEV S LS G GPG LL A QY EL +L VQASSWQG +A Sbjct 7 FAVPPEVPSAWLSTGMGPGPLLAA---------QYTEIATELASVLAAVQASSWQGPSAD 57 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++V AH P+ WL A + AA H AAA Y SAL MPT AELAANHA+HG L+ T Sbjct 58 RFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTT 117 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGG---- 176 NFFG+NT+PIALNEADY+RMW+QAA M+ YQAVA + A PST PAP I Sbjct 118 NFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAA 177 Query 177 -----DAADTRLDVLSSIGQLIR----DIL-----DFIANPYKYFLEFFEQFGFSPAVTV 222 D L +L +L+R ++L D IA +F+ F P T Sbjct 178 SISFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVS----GPVFTF 233 Query 223 VLALVALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAG-LLPIAAA 281 + LV L Y+ + L P P + LT L+ L + PAG ++ + Sbjct 234 LAYLVLDPLI------YFGPFAPLTSPVLLP--AGLTGLAGLGAVSG--PAGPMVERVHS 283 Query 282 LGPGDQ-WGANLAVAV---TPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVP 337 GP Q W A V + PA PT++ AP APS+ +SAA G+ YAV Sbjct 284 DGPSRQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTP---GSSAAQGL-YAVG 339 Query 338 GLAPPGVSSGPKAGTKSPDTAADTLATAGAARPG-LARAHRRKRSESGVGIRGYRDEFL- 395 G P G P A T + A A PG A++ K + +R +R EFL Sbjct 340 G--PDGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLA 397 Query 396 -DATATVDAATDVPAPAN-AAGSQGAGTLGFAGTAPTTS-GAAAGMVQL-SSHSTSTTVP 451 D T+ + P A+ AAG++G LGFAGT P ++ G+A G+ L + + P Sbjct 398 DDGRLTMP---NTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQP 454 Query 452 LLPTTW 457 +LP TW Sbjct 455 MLPHTW 460 >gi|289441176|ref|ZP_06430920.1| PPE family protein [Mycobacterium tuberculosis T46] gi|289414095|gb|EFD11335.1| PPE family protein [Mycobacterium tuberculosis T46] Length=427 Score = 195 bits (496), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 101/169 (60%), Positives = 118/169 (70%), Gaps = 0/169 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A PPEVHS LLSAG GP SL AA +W LS +YA A EL +L VQ +W+G +A Sbjct 24 FASPPEVHSALLSAGPGPASLQAAAAEWTSLSAEYASAAQELTAVLAAVQGGAWEGPSAE 83 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PYLAWL +++ +SA A QH AY SALAAMPT ELAANH H VL+ T Sbjct 84 AYVAAHLPYLAWLTKSSADSARLATQHEVMTTAYASALAAMPTLTELAANHTSHAVLLGT 143 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAP 169 NFFGINT+PIALNEADY RMW+QAA TM+ Y+ +DAA + P T PAP Sbjct 144 NFFGINTIPIALNEADYARMWIQAATTMSIYEGTSDAALASAPQTTPAP 192 >gi|240173305|ref|ZP_04751963.1| PPE family protein, PPE3 [Mycobacterium kansasii ATCC 12478] Length=523 Score = 194 bits (492), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 135/270 (50%), Positives = 160/270 (60%), Gaps = 36/270 (13%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS+G GPGSLL AA W LS +Y A EL +LG VQ +W+G +A Sbjct 6 MASPPEVHSALLSSGPGPGSLLSAAAAWSALSAEYGTAADELMVVLGAVQGGAWEGPSAE 65 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 +YVAAH PYL WL Q SA AA+H AAAY SAL AMPT AELAANHAIHGVL+AT Sbjct 66 RYVAAHVPYLMWLMQAGTVSAAAAARHETVAAAYSSALGAMPTLAELAANHAIHGVLVAT 125 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI--------- 171 NFFGINT+PIALNEADYVRMW+QAA TMA Y+AV+ AA + P T PAP I Sbjct 126 NFFGINTIPIALNEADYVRMWIQAATTMATYEAVSGAAVASTPQTSPAPQIVTAEADDGH 185 Query 172 -RAPGGDAA---DTRLDVLSSI--GQLIRDILDFIAN--PYKYF-------------LEF 210 GGD + +VL I G++I D + N PY + LEF Sbjct 186 DHEHGGDPTPIDNFVAEVLRIITGGRVIWDPAEGTVNGIPYDEYTNAAQPIWWLVRALEF 245 Query 211 FEQFG------FSPAVTVVLALVALQLYDF 234 + F F+ + LV L L+D+ Sbjct 246 SQDFQTFAKELFTNPAAAMQFLVELMLFDW 275 >gi|57116948|ref|YP_177861.1| PPE family protein [Mycobacterium tuberculosis H37Rv] gi|148661938|ref|YP_001283461.1| PPE family protein [Mycobacterium tuberculosis H37Ra] gi|167967467|ref|ZP_02549744.1| PPE family protein [Mycobacterium tuberculosis H37Ra] 35 more sequence titles Length=473 Score = 194 bits (492), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 188/482 (40%), Positives = 247/482 (52%), Gaps = 44/482 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A+PPEV S LS G GPG LL AA+ W L+ QY EL +L VQASSWQG +A Sbjct 7 FAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSAD 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++V AH P+ WL A + AA H AAA Y SAL MPT AELAANHA+HG L+ T Sbjct 67 RFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFG+NT+PIALNEADY+RMW+QAA M+ YQAVA + A PST PAP I +A Sbjct 127 NFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAA 186 Query 181 TRL--DVLSSIGQLIRDILDF------------IANPYKYFLEFFEQFGFSPAVTVVLAL 226 + D I QL++D L+ + + L++F F P T + L Sbjct 187 SSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFTFLAYL 246 Query 227 VALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAG-LLPIAAALGPG 285 V L Y+ + L P P + LT L+ L + PAG ++ + GP Sbjct 247 VLDPLI------YFGPFAPLTSPVLLP--AGLTGLAGLGAVSG--PAGPMVERVHSDGPS 296 Query 286 DQ-WGANLAVAV---TPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAP 341 Q W A V + PA PT++ AP APS+ +SAA G+ YAV G P Sbjct 297 RQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTP---GSSAAQGL-YAVGG--P 350 Query 342 PGVSSGPKAGTKSPDTAADTLATAGAARPG-LARAHRRKRSESGVGIRGYRDEFL--DAT 398 G P A T + A A PG A++ K + +R +R EFL D Sbjct 351 DGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGR 410 Query 399 ATVDAATDVPAPAN-AAGSQGAGTLGFAGTAPTTS-GAAAGMVQL-SSHSTSTTVPLLPT 455 T+ + P A+ AAG++G LGFAGT P ++ G+A G+ L + + P+LP Sbjct 411 LTMP---NTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPH 467 Query 456 TW 457 TW Sbjct 468 TW 469 >gi|340627132|ref|YP_004745584.1| PPE family protein [Mycobacterium canettii CIPT 140010059] gi|340005322|emb|CCC44479.1| PPE family protein [Mycobacterium canettii CIPT 140010059] Length=473 Score = 194 bits (492), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 188/482 (40%), Positives = 247/482 (52%), Gaps = 44/482 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A+PPEV S LS G GPG LL AA+ W L+ QY EL +L VQASSWQG +A Sbjct 7 FAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSAD 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++V AH P+ WL A + AA H AAA Y SAL MPT AELAANHA+HG L+ T Sbjct 67 RFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALVTT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFG+NT+PIALNEADY+RMW+QAA M+ YQAVA + A PST PAP I +A Sbjct 127 NFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAA 186 Query 181 TRL--DVLSSIGQLIRDILDF------------IANPYKYFLEFFEQFGFSPAVTVVLAL 226 + D I QL++D L+ + + L++F F P T + L Sbjct 187 SSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFTFLAYL 246 Query 227 VALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAG-LLPIAAALGPG 285 V L Y+ + L P P + LT L+ L + PAG ++ + GP Sbjct 247 VLDPLI------YFGPFAPLTSPVLLP--AGLTGLAGLGAVSG--PAGPMVESVHSDGPS 296 Query 286 DQ-WGANLAVAV---TPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAP 341 Q W A V + PA PT++ AP APS+ +SAA G+ YAV G P Sbjct 297 RQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTP---GSSAAQGL-YAVGG--P 350 Query 342 PGVSSGPKAGTKSPDTAADTLATAGAARPG-LARAHRRKRSESGVGIRGYRDEFL--DAT 398 G P A T + A A PG A++ K + +R +R EFL D Sbjct 351 DGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGR 410 Query 399 ATVDAATDVPAPAN-AAGSQGAGTLGFAGTAPTTS-GAAAGMVQL-SSHSTSTTVPLLPT 455 T+ + P A+ AAG++G LGFAGT P ++ G+A G+ L + + P+LP Sbjct 411 LTMP---NTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPH 467 Query 456 TW 457 TW Sbjct 468 TW 469 >gi|289447743|ref|ZP_06437487.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] gi|289420701|gb|EFD17902.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] Length=473 Score = 193 bits (491), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 188/482 (40%), Positives = 247/482 (52%), Gaps = 44/482 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A+PPEV S LS G GPG LL AA+ W L+ QY EL +L VQASSWQG +A Sbjct 7 FAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSAD 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++V AH P+ WL A + AA H AAA Y SAL MPT AELAANHA+HG L+ T Sbjct 67 RFVVAHQPFRYWLTHAATVATAAAAAHETAAAGYTSALGGMPTLAELAANHAMHGALMTT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFG+NT+PIALNEADY+RMW+QAA M+ YQAVA + A PST PAP I +A Sbjct 127 NFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAA 186 Query 181 TRL--DVLSSIGQLIRDILDF------------IANPYKYFLEFFEQFGFSPAVTVVLAL 226 + D I QL++D L+ + + L++F F P T + L Sbjct 187 SSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFTFLAYL 246 Query 227 VALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAG-LLPIAAALGPG 285 V L Y+ + L P P + LT L+ L + PAG ++ + GP Sbjct 247 VLDPLI------YFGPFAPLTSPVLLP--AGLTGLAGLGAVSG--PAGPMVERVHSDGPS 296 Query 286 DQ-WGANLAVAV---TPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAP 341 Q W A V + PA PT++ AP APS+ +SAA G+ YAV G P Sbjct 297 RQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTP---GSSAAQGL-YAVGG--P 350 Query 342 PGVSSGPKAGTKSPDTAADTLATAGAARPG-LARAHRRKRSESGVGIRGYRDEFL--DAT 398 G P A T + A A PG A++ K + +R +R EFL D Sbjct 351 DGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGR 410 Query 399 ATVDAATDVPAPAN-AAGSQGAGTLGFAGTAPTTS-GAAAGMVQL-SSHSTSTTVPLLPT 455 T+ + P A+ AAG++G LGFAGT P ++ G+A G+ L + + P+LP Sbjct 411 LTMP---NTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPH 467 Query 456 TW 457 TW Sbjct 468 TW 469 >gi|118468729|ref|YP_885030.1| PPE family protein [Mycobacterium smegmatis str. MC2 155] gi|118170016|gb|ABK70912.1| ppe family protein [Mycobacterium smegmatis str. MC2 155] Length=523 Score = 192 bits (488), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 206/510 (41%), Positives = 267/510 (53%), Gaps = 59/510 (11%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA+PPEVHS LLS+G GPGSLL AA WQ LS +YA A AEL +L VQA SW+G ++ Sbjct 7 MALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAEYAAAAAELTSVLSAVQAGSWEGPSSE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PYL WL Q + NSA A QH AAAAY +ALA MPT AELA NH +HGVL+AT Sbjct 67 QYVAAHAPYLQWLAQQSANSAAAAVQHETAAAAYSTALATMPTMAELALNHTMHGVLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPG-GDAA 179 NFFGINT+PIALNEADYVRMW+QAA TM+ YQAV+ AA A P + PAP + PG G+A Sbjct 127 NFFGINTIPIALNEADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVGEAG 186 Query 180 DTRLDVLSSIGQLI----------------------------RDILDFIANPYKYFLEFF 211 V Q + ILDF+ +P Sbjct 187 SASASVQQMSAQATAAESGSSLDLSSIISDLLNQYLQGVPGGQAILDFLKDPLGNLGRLL 246 Query 212 EQFGFSPAVTV-----VLALVALQL-YDFLWYPYYASYGLLLL-PFFTPTLSAL--TALS 262 F +PA + L VA Q+ ++ + +P ++G++ PF P L+AL T L Sbjct 247 TDFMTNPAGALATWWPFLFGVAYQVFFNLVGWP---TWGMIFASPFLIPALAALGITGLV 303 Query 263 ALI-HLLN----LPPAGLLPIAAALGPG-DQWGANLAVAVTPATAAVPGGSPPTSNPAPA 316 LI H+LN +P P A P DQ LAV ++P A VPG + + PAPA Sbjct 304 LLIDHVLNNPVDVPAEDEAPQEVAAAPRTDQ---PLAVGISP--AGVPGSAATAAAPAPA 358 Query 317 APSSN-SVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADT---LATAGAARPGL 372 + + + +AA + YAV PG P G KS A + A +G A Sbjct 359 PAGTTVAAPAPAAATFVPYAVANRD-PGEGFTPTLGNKSQVAAPASGVPAAASGVAASLA 417 Query 373 ARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAPTTS 432 +R RR++ + + RGY D ++D + P P A +G+ +GF GT Sbjct 418 SRRKRRRKKGAQIEERGYADAYMDYEEPDEDPAPQPEPRVRASERGSDAMGFTGTVTRHD 477 Query 433 GAAAGMVQLS--SHSTSTTVPLLPTTWTTD 460 AAG+ L+ + P+LP TW D Sbjct 478 VTAAGLTTLTGDTFDDRPVTPMLPGTWDGD 507 >gi|169629316|ref|YP_001702965.1| PPE family protein [Mycobacterium abscessus ATCC 19977] gi|169241283|emb|CAM62311.1| Hypothetical PPE family protein [Mycobacterium abscessus] Length=523 Score = 191 bits (485), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 138/271 (51%), Positives = 168/271 (62%), Gaps = 32/271 (11%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLSAG GPG+LL AA QWQ LS QY A EL QLL + SWQG +A Sbjct 7 MASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTAATELTQLLAATGSGSWQGPSAA 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVA+H PYLAWL Q + SA A H +AAAY +ALAAMPT AELAANH IHGVL+AT Sbjct 67 QYVASHAPYLAWLTQQSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIHGVLLAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGD--- 177 NFFGINT+PIALNEADY+RMW+QAA TM YQ V+ AA +V T PAP I APGG+ Sbjct 127 NFFGINTIPIALNEADYIRMWIQAATTMGVYQGVSTAAVTSVAPTPPAPTIMAPGGEMSR 186 Query 178 -------------AADTRL---DVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVT 221 AA++ + D S +L+R I +F ++P + + F +P Sbjct 187 MSADMSGMAAQAQAAESGMALDDSESFFDKLMRQIQEFFSDPLGTLQKILQDFMRNP--- 243 Query 222 VVLALVALQLYDFLWYP--YYASYGLLLLPF 250 + ALVA W P ++ +Y +PF Sbjct 244 -LEALVA-------WGPLLFFIAYEAFFIPF 266 >gi|308232040|ref|ZP_07414707.2| PPE family protein [Mycobacterium tuberculosis SUMu001] gi|308379125|ref|ZP_07485142.2| PPE family protein [Mycobacterium tuberculosis SUMu010] gi|308380275|ref|ZP_07489361.2| PPE family protein [Mycobacterium tuberculosis SUMu011] gi|308215216|gb|EFO74615.1| PPE family protein [Mycobacterium tuberculosis SUMu001] gi|308358092|gb|EFP46943.1| PPE family protein [Mycobacterium tuberculosis SUMu010] gi|308362026|gb|EFP50877.1| PPE family protein [Mycobacterium tuberculosis SUMu011] Length=473 Score = 190 bits (483), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 187/482 (39%), Positives = 246/482 (52%), Gaps = 44/482 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 A+PPEV S LS G GPG LL AA+ W L+ QY EL +L VQASSWQG +A Sbjct 7 FAVPPEVPSAWLSTGMGPGPLLAAARAWHALAAQYTEIATELASVLAAVQASSWQGPSAD 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 ++V AH P+ WL A + AA H AAA SAL MPT AELAANHA+HG L+ T Sbjct 67 RFVVAHQPFRYWLTHAATVATAAAAAHETAAAGNTSALGGMPTLAELAANHAMHGALVTT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFG+NT+PIALNEADY+RMW+QAA M+ YQAVA + A PST PAP I +A Sbjct 127 NFFGVNTIPIALNEADYLRMWIQAATVMSHYQAVAHESVAATPSTPPAPQIVTSAASSAA 186 Query 181 TRL--DVLSSIGQLIRDILDF------------IANPYKYFLEFFEQFGFSPAVTVVLAL 226 + D I QL++D L+ + + L++F F P T + L Sbjct 187 SSSFPDPTKLILQLLKDFLELLRYLAVELLPGPLGDLIAQVLDWFISFVSGPVFTFLAYL 246 Query 227 VALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAG-LLPIAAALGPG 285 V L Y+ + L P P + LT L+ L + PAG ++ + GP Sbjct 247 VLDPLI------YFGPFAPLTSPVLLP--AGLTGLAGLGAVSG--PAGPMVERVHSDGPS 296 Query 286 DQ-WGANLAVAV---TPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAP 341 Q W A V + PA PT++ AP APS+ +SAA G+ YAV G P Sbjct 297 RQSWPAATGVTLVGTNPAALVTTPAPAPTTSAAPTAPSTP---GSSAAQGL-YAVGG--P 350 Query 342 PGVSSGPKAGTKSPDTAADTLATAGAARPG-LARAHRRKRSESGVGIRGYRDEFL--DAT 398 G P A T + A A PG A++ K + +R +R EFL D Sbjct 351 DGEGFNPIAKTTALAGVTTDAAAPAAKLPGDQAQSSASKATRLRRRLRQHRFEFLADDGR 410 Query 399 ATVDAATDVPAPAN-AAGSQGAGTLGFAGTAPTTS-GAAAGMVQL-SSHSTSTTVPLLPT 455 T+ + P A+ AAG++G LGFAGT P ++ G+A G+ L + + P+LP Sbjct 411 LTMP---NTPEMADVAAGNRGLDALGFAGTIPKSAPGSATGLTHLGGGFADVLSQPMLPH 467 Query 456 TW 457 TW Sbjct 468 TW 469 >gi|118616922|ref|YP_905254.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118569032|gb|ABL03783.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=517 Score = 190 bits (482), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 109/176 (62%), Positives = 128/176 (73%), Gaps = 0/176 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 +A PPEVHS +LS+G GP SLL AA W LS +YAL AEL ++L VQA +WQG + Sbjct 10 IASPPEVHSAMLSSGPGPASLLAAAGVWSALSAEYALTAAELSEVLAAVQAGAWQGPSGF 69 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PY+AWL Q + + A AA+H AAA AY ALAAMPT EL ANHA+HGVL+AT Sbjct 70 QYVAAHLPYVAWLLQASADGAGKAAEHEAAAVAYSGALAAMPTLTELGANHALHGVLVAT 129 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGG 176 NFFG+N +PIALNEADYVRMW+QAA TM YQA A AA + P T P P + PGG Sbjct 130 NFFGLNAIPIALNEADYVRMWVQAATTMGLYQATAGAALASAPRTGPPPKVVNPGG 185 >gi|183980573|ref|YP_001848864.1| PPE family protein, PPE4 [Mycobacterium marinum M] gi|183173899|gb|ACC39009.1| PPE family protein, PPE4 [Mycobacterium marinum M] Length=517 Score = 189 bits (481), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 109/176 (62%), Positives = 128/176 (73%), Gaps = 0/176 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 +A PPEVHS +LS+G GP SLL AA W LS +YAL AEL ++L VQA +WQG + Sbjct 10 IASPPEVHSAMLSSGPGPASLLAAAGVWSALSAEYALTAAELSEVLAAVQAGAWQGPSGF 69 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PY+AWL Q + + A AA+H AAA AY ALAAMPT EL ANHA+HGVL+AT Sbjct 70 QYVAAHLPYVAWLLQASADGAGKAAEHEAAAVAYSGALAAMPTLTELGANHALHGVLVAT 129 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGG 176 NFFG+N +PIALNEADYVRMW+QAA TM YQA A AA + P T P P + PGG Sbjct 130 NFFGLNAIPIALNEADYVRMWVQAATTMGLYQATAGAALASAPRTGPPPKVVNPGG 185 >gi|296167571|ref|ZP_06849908.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897137|gb|EFG76747.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=354 Score = 189 bits (481), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 132/272 (49%), Positives = 160/272 (59%), Gaps = 40/272 (14%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS+G GP SLL AA W ELS +YA A A+L +L QA SWQG +A Sbjct 7 MASPPEVHSALLSSGPGPASLLAAAGAWSELSAEYASAAAQLSGVLAAAQAGSWQGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PYLAWL + + +SA AAQH AA AY +ALA MPT ELAANHA+HG L+AT Sbjct 67 SYVAAHAPYLAWLTRASADSAAAAAQHETAAVAYTAALATMPTLPELAANHAVHGALVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPI-------RA 173 NFFG+NTVPIALNEADY RMW+QAA TM YQAV+ AA + P +PAP I Sbjct 127 NFFGVNTVPIALNEADYARMWVQAAGTMTTYQAVSTAAVASTPQPEPAPQIVKSAAASHD 186 Query 174 PGGDAADTRLDVLSSIGQLIRDILDFIAN------------PYKYF-------------- 207 GGD D ++ + + Q I +IL + PY + Sbjct 187 SGGDVHDPTIN--NPLDQFIANILKNLGINWDPAQGTVNGLPYDAYTNAGEPLFWVVRAL 244 Query 208 --LEFFEQFGFSPAVTVVLA---LVALQLYDF 234 LE F+QFG+ LA +V L L+D+ Sbjct 245 ELLEDFQQFGYYLVHNPALAFQYIVQLMLFDW 276 >gi|240171483|ref|ZP_04750142.1| PPE-family protein [Mycobacterium kansasii ATCC 12478] Length=535 Score = 188 bits (477), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 115/207 (56%), Positives = 141/207 (69%), Gaps = 8/207 (3%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 +A PPEVHS LL++G GP LL AA W LSD+YA AELG LL VQA W+G +A Sbjct 7 LASPPEVHSALLNSGPGPEPLLTAAAGWSSLSDEYAAVAAELGTLLAAVQAGVWRGPSAD 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 +VAA+GPYLAWL Q + ++A A +H AAAY +ALAAMPT ELAANHA H L+AT Sbjct 67 AFVAAYGPYLAWLAQASADTATAATRHETLAAAYTAALAAMPTLPELAANHASHAGLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPG----- 175 NFFGINT+PIALNEADY+RMW+QAA TMA YQA++ +A ++P T PAPPI Sbjct 127 NFFGINTIPIALNEADYLRMWIQAATTMATYQAISGSAVTSIPQTGPAPPILKSNTPAQE 186 Query 176 -GDAADTRLDVLSSIGQLIRDILDFIA 201 G A D+ + I LI +IL I+ Sbjct 187 SGKAGDS--GHATPIDNLIAEILKVIS 211 >gi|145220929|ref|YP_001131607.1| PPE protein [Mycobacterium gilvum PYR-GCK] gi|145213415|gb|ABP42819.1| PPE protein [Mycobacterium gilvum PYR-GCK] Length=540 Score = 184 bits (468), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 122/231 (53%), Positives = 148/231 (65%), Gaps = 22/231 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA+PPEVHS +LS+G GPGSLL A WQ LS +YA A AEL +L VQ+ +W+G ++ Sbjct 17 MALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAEYASAAAELTSILAGVQSGAWEGPSSQ 76 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PYLAWL Q + SA TA QH AAAAY +ALA MPT ELA NH H VL+ T Sbjct 77 QYVAAHTPYLAWLAQQSAVSAATAVQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGT 136 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPG-GDA- 178 NF GINT+PIALNEADYVRMW+QAA TMA YQ+V+ AA A P++ PAP + PG G+A Sbjct 137 NFLGINTIPIALNEADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAG 196 Query 179 -----------------ADTRLDVLSSIGQLIR---DILDFIANPYKYFLE 209 A DV + I +IR ++L F+ P FL Sbjct 197 RAAADMSAFAAQPMAAQAGAAFDVSNIIADIIRLYGEVLRFLFEPIFNFLR 247 >gi|169631856|ref|YP_001705505.1| PPE family protein [Mycobacterium abscessus ATCC 19977] gi|169243823|emb|CAM64851.1| PPE family protein [Mycobacterium abscessus] Length=496 Score = 184 bits (468), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 112/246 (46%), Positives = 139/246 (57%), Gaps = 24/246 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS+G GPGSL AA W+ LS +Y+ A EL LG V+A W G +A Sbjct 7 MAAPPEVHSALLSSGPGPGSLFAAADAWRSLSTEYSSAANELTTTLGSVRAGVWDGASAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QY AH PYL+WL +T+ SA AAQ AA AY ALA MPT ELAANHA HG L+AT Sbjct 67 QYQTAHVPYLSWLHETSAVSAGVAAQTETAATAYSEALATMPTLGELAANHATHGALVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAAT-----------VAVPS----- 164 NFFGINT+PIA+NEADY+RMW+QAA M+ YQAV++++ V P Sbjct 127 NFFGINTIPIAVNEADYIRMWIQAATVMSTYQAVSESSVSAAPPTSPAPPVLSPDSGAAA 186 Query 165 -------TQPAPPIRAPGGDAADTRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFS 217 T+P PPI D + L + R + I +P + F + Sbjct 187 RTAAQDATKP-PPIVPDPNDPIEMLLKNSQHFLGMYRALKGLITDPVGTIVRIIIDFSTN 245 Query 218 PAVTVV 223 PA +V Sbjct 246 PAAAIV 251 >gi|308376353|ref|ZP_07438549.2| putative PPE family protein [Mycobacterium tuberculosis SUMu008] gi|308351359|gb|EFP40210.1| putative PPE family protein [Mycobacterium tuberculosis SUMu008] Length=332 Score = 184 bits (468), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 117/181 (65%), Positives = 132/181 (73%), Gaps = 0/181 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS G GPGSL+ AA W +LS +YA AEL LLG V +WQG +A Sbjct 7 MASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PY+AWL Q + ++A AAQH AAAAAY +ALAAMPT AELAANH IH VL+AT Sbjct 67 WYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PI LNEADYVRMWLQAA M YQA + AA + P T PAP + PGG AA Sbjct 127 NFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAAS 186 Query 181 T 181 T Sbjct 187 T 187 >gi|167967058|ref|ZP_02549335.1| PPE family protein [Mycobacterium tuberculosis H37Ra] Length=335 Score = 184 bits (467), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 117/181 (65%), Positives = 132/181 (73%), Gaps = 0/181 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS G GPGSL+ AA W +LS +YA AEL LLG V +WQG +A Sbjct 7 MASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PY+AWL Q + ++A AAQH AAAAAY +ALAAMPT AELAANH IH VL+AT Sbjct 67 WYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PI LNEADYVRMWLQAA M YQA + AA + P T PAP + PGG AA Sbjct 127 NFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAAS 186 Query 181 T 181 T Sbjct 187 T 187 >gi|315442101|ref|YP_004074980.1| PPE-repeat containing protein [Mycobacterium sp. Spyr1] gi|315260404|gb|ADT97145.1| PPE-repeat containing protein [Mycobacterium sp. Spyr1] Length=530 Score = 184 bits (467), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 122/231 (53%), Positives = 148/231 (65%), Gaps = 22/231 (9%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA+PPEVHS +LS+G GPGSLL A WQ LS +YA A AEL +L VQ+ +W+G ++ Sbjct 7 MALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAEYASAAAELTSILAGVQSGAWEGPSSQ 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 QYVAAH PYLAWL Q + SA TA QH AAAAY +ALA MPT ELA NH H VL+ T Sbjct 67 QYVAAHTPYLAWLAQQSAVSAATAVQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPG-GDA- 178 NF GINT+PIALNEADYVRMW+QAA TMA YQ+V+ AA A P++ PAP + PG G+A Sbjct 127 NFLGINTIPIALNEADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAG 186 Query 179 -----------------ADTRLDVLSSIGQLIR---DILDFIANPYKYFLE 209 A DV + I +IR ++L F+ P FL Sbjct 187 RAAADMSAFAAQPMAAQAGAAFDVSNIIADIIRLYGEVLRFLFEPIFNFLR 237 >gi|298523757|ref|ZP_07011166.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A] gi|298493551|gb|EFI28845.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A] Length=379 Score = 184 bits (467), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 117/181 (65%), Positives = 132/181 (73%), Gaps = 0/181 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS G GPGSL+ AA W +LS +YA AEL LLG V +WQG +A Sbjct 7 MASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PY+AWL Q + ++A AAQH AAAAAY +ALAAMPT AELAANH IH VL+AT Sbjct 67 WYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PI LNEADYVRMWLQAA M YQA + AA + P T PAP + PGG AA Sbjct 127 NFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAAS 186 Query 181 T 181 T Sbjct 187 T 187 >gi|307078212|ref|ZP_07487382.1| putative PPE family protein [Mycobacterium tuberculosis SUMu011] gi|308363847|gb|EFP52698.1| putative PPE family protein [Mycobacterium tuberculosis SUMu011] Length=342 Score = 184 bits (467), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 117/181 (65%), Positives = 132/181 (73%), Gaps = 0/181 (0%) Query 1 MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAAT 60 MA PPEVHS LLS G GPGSL+ AA W +LS +YA AEL LLG V +WQG +A Sbjct 7 MASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAE 66 Query 61 QYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIAT 120 YVAAH PY+AWL Q + ++A AAQH AAAAAY +ALAAMPT AELAANH IH VL+AT Sbjct 67 WYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVAT 126 Query 121 NFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAAD 180 NFFGINT+PI LNEADYVRMWLQAA M YQA + AA + P T PAP + PGG AA Sbjct 127 NFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAAS 186 Query 181 T 181 T Sbjct 187 T 187 Lambda K H 0.315 0.129 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 973451812480 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40