BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0099 Length=540 Score E Sequences producing significant alignments: (Bits) Value gi|15607241|ref|NP_214613.1| acyl-CoA synthetase [Mycobacterium ... 1087 0.0 gi|289756161|ref|ZP_06515539.1| fatty-acid-CoA ligase fadD10 [My... 1084 0.0 gi|167968257|ref|ZP_02550534.1| acyl-CoA synthetase [Mycobacteri... 1070 0.0 gi|340625135|ref|YP_004743587.1| putative fatty-acid-CoA ligase ... 1066 0.0 gi|306778926|ref|ZP_07417263.1| fatty-acid-CoA ligase fadD10 [My... 1053 0.0 gi|289764215|ref|ZP_06523593.1| fatty-acid-CoA ligase fadD10 [My... 1027 0.0 gi|118619896|ref|YP_908228.1| acyl-CoA synthetase [Mycobacterium... 857 0.0 gi|183980290|ref|YP_001848581.1| fatty-acid-CoA ligase FadD10 [M... 856 0.0 gi|15828082|ref|NP_302345.1| acyl-CoA synthetase [Mycobacterium ... 797 0.0 gi|308394434|ref|ZP_07491679.2| putative AMP-binding enzyme [Myc... 734 0.0 gi|317506388|ref|ZP_07964197.1| AMP-binding enzyme [Segniliparus... 696 0.0 gi|169627764|ref|YP_001701413.1| acyl-CoA synthetase [Mycobacter... 642 0.0 gi|307082567|ref|ZP_07491680.1| hypothetical protein TMLG_00838 ... 612 6e-173 gi|297153933|gb|ADI03645.1| long-chain-fatty-acid--CoA ligase [S... 243 4e-62 gi|302527900|ref|ZP_07280242.1| dicarboxylate-CoA ligase PimA [S... 235 2e-59 gi|29827146|ref|NP_821780.1| long-chain-fatty-acid--CoA ligase [... 216 7e-54 gi|238632107|gb|ACR50792.1| putative acyl-CoA synthase [Streptom... 213 8e-53 gi|261855561|ref|YP_003262844.1| AMP-dependent synthetase and li... 204 2e-50 gi|329940134|ref|ZP_08289416.1| substrate-CoA ligase [Streptomyc... 201 2e-49 gi|29828821|ref|NP_823455.1| long-chain-fatty-acid--CoA ligase [... 197 5e-48 gi|310818957|ref|YP_003951315.1| AMP-dependent synthetase and li... 196 7e-48 gi|124007603|ref|ZP_01692307.1| AMP-dependent synthetase and lig... 194 3e-47 gi|291442742|ref|ZP_06582132.1| acyl-CoA synthetase [Streptomyce... 191 4e-46 gi|311896126|dbj|BAJ28534.1| putative long-chain fatty-acid--CoA... 184 5e-44 gi|226312168|ref|YP_002772062.1| acyl-CoA synthetase [Brevibacil... 183 7e-44 gi|339321983|ref|YP_004680877.1| long-chain-fatty-acid--CoA liga... 182 1e-43 gi|116694665|ref|YP_728876.1| long-chain-fatty-acid--CoA ligase ... 179 1e-42 gi|262194900|ref|YP_003266109.1| AMP-dependent synthetase and li... 177 3e-42 gi|73537400|ref|YP_297767.1| long-chain-fatty-acid--CoA ligase [... 177 5e-42 gi|192289242|ref|YP_001989847.1| AMP-dependent synthetase and li... 176 6e-42 gi|149185931|ref|ZP_01864246.1| acyl-CoA synthase [Erythrobacter... 176 9e-42 gi|197105973|ref|YP_002131350.1| long-chain-fatty-acid--CoA liga... 176 1e-41 gi|85375345|ref|YP_459407.1| long-chain-fatty-acid--CoA ligase [... 176 1e-41 gi|149919197|ref|ZP_01907680.1| putative long-chain-fatty-acid--... 174 3e-41 gi|103487349|ref|YP_616910.1| acyl-CoA synthetase [Sphingopyxis ... 174 4e-41 gi|51891936|ref|YP_074627.1| putative long-chain fatty-acid-CoA ... 174 5e-41 gi|94313871|ref|YP_587080.1| acyl-CoA synthetase [Cupriavidus me... 173 6e-41 gi|159036889|ref|YP_001536142.1| AMP-dependent synthetase and li... 171 2e-40 gi|341820478|emb|CCC56759.1| acyl-CoA synthetase (AMP-forming)/A... 171 3e-40 gi|145220633|ref|YP_001131311.1| AMP-dependent synthetase and li... 171 4e-40 gi|39933820|ref|NP_946096.1| putative acid-CoA ligase [Rhodopseu... 171 4e-40 gi|156741756|ref|YP_001431885.1| AMP-dependent synthetase and li... 170 6e-40 gi|194291334|ref|YP_002007241.1| long-chain-fatty-acid--CoA liga... 169 8e-40 gi|86751180|ref|YP_487676.1| AMP-dependent synthetase and ligase... 169 8e-40 gi|315442419|ref|YP_004075298.1| acyl-CoA synthetase (AMP-formin... 169 1e-39 gi|333370466|ref|ZP_08462468.1| long-chain-fatty-acid-CoA ligase... 169 2e-39 gi|91978271|ref|YP_570930.1| AMP-dependent synthetase and ligase... 169 2e-39 gi|146339585|ref|YP_001204633.1| long-chain-fatty-acid--CoA liga... 168 2e-39 gi|148254372|ref|YP_001238957.1| long-chain-fatty-acid--CoA liga... 168 3e-39 gi|90423185|ref|YP_531555.1| long-chain-fatty-acid--CoA ligase [... 167 5e-39 >gi|15607241|ref|NP_214613.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Rv] gi|15839479|ref|NP_334516.1| acyl-CoA synthetase [Mycobacterium tuberculosis CDC1551] gi|31791277|ref|NP_853770.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97] 45 more sequence titles Length=540 Score = 1087 bits (2812), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/540 (100%), Positives = 540/540 (100%), Gaps = 0/540 (0%) Query 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA Sbjct 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 Query 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA Sbjct 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 Query 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT Sbjct 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG Sbjct 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 Query 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA Sbjct 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 Query 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG Sbjct 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 Query 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 420 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI Sbjct 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 420 Query 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES Sbjct 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 Query 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG Sbjct 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 >gi|289756161|ref|ZP_06515539.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis EAS054] gi|289696748|gb|EFD64177.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis EAS054] Length=540 Score = 1084 bits (2803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 539/540 (99%), Positives = 539/540 (99%), Gaps = 0/540 (0%) Query 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 MGGKKFQAM QLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA Sbjct 1 MGGKKFQAMLQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 Query 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA Sbjct 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 Query 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT Sbjct 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG Sbjct 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 Query 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA Sbjct 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 Query 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG Sbjct 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 Query 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 420 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI Sbjct 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 420 Query 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES Sbjct 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 Query 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG Sbjct 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 >gi|167968257|ref|ZP_02550534.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Ra] gi|254549033|ref|ZP_05139480.1| acyl-CoA synthetase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|294992944|ref|ZP_06798635.1| acyl-CoA synthetase [Mycobacterium tuberculosis 210] 6 more sequence titles Length=532 Score = 1070 bits (2768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 532/532 (100%), Positives = 532/532 (100%), Gaps = 0/532 (0%) Query 9 MPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR 68 MPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR Sbjct 1 MPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR 60 Query 69 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS 128 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS Sbjct 61 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS 120 Query 129 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL 188 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL Sbjct 121 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL 180 Query 189 LANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN 248 LANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN Sbjct 181 LANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN 240 Query 249 TTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEA 308 TTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEA Sbjct 241 TTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEA 300 Query 309 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGA 368 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGA Sbjct 301 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGA 360 Query 369 GPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMI 428 GPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMI Sbjct 361 GPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMI 420 Query 429 ICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHT 488 ICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHT Sbjct 421 ICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHT 480 Query 489 IAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 IAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG Sbjct 481 IAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 532 >gi|340625135|ref|YP_004743587.1| putative fatty-acid-CoA ligase FADD10 [Mycobacterium canettii CIPT 140010059] gi|340003325|emb|CCC42443.1| putative fatty-acid-CoA ligase FADD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) [Mycobacterium canettii CIPT 140010059] Length=540 Score = 1066 bits (2758), Expect = 0.0, Method: Compositional matrix adjust. Identities = 528/540 (98%), Positives = 534/540 (99%), Gaps = 0/540 (0%) Query 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 MGGKKFQAMPQLPSTVLDRVFEQARQ+PEAIALRRCDGTSALRYRELVAEVGGLAA LRA Sbjct 1 MGGKKFQAMPQLPSTVLDRVFEQARQRPEAIALRRCDGTSALRYRELVAEVGGLAAALRA 60 Query 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 QSV+RGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA Sbjct 61 QSVTRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 Query 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT Sbjct 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TGEPKAVLLANRTFFAVPDILQKEGLNW+TWVVGETTYSPLPATHIGGLWWILTCLMHGG Sbjct 181 TGEPKAVLLANRTFFAVPDILQKEGLNWITWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 Query 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA Sbjct 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 Query 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSI KIEAGAVGRPYPGVDVYLAAT+G Sbjct 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIAKIEAGAVGRPYPGVDVYLAATNG 360 Query 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 420 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDG+FYI Sbjct 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGYFYI 420 Query 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 KGRSSEMIICGGVNIAPDEVDRIAEGV GVREAACYEIPDEEFGALVGLAVVASAELDES Sbjct 421 KGRSSEMIICGGVNIAPDEVDRIAEGVPGVREAACYEIPDEEFGALVGLAVVASAELDES 480 Query 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 AARALKHTI+ARFRRESEPMARPS I IVTDIPRTQSGKVMRASLAAA TADKARVVVRG Sbjct 481 AARALKHTISARFRRESEPMARPSIIEIVTDIPRTQSGKVMRASLAAATTADKARVVVRG 540 >gi|306778926|ref|ZP_07417263.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis SUMu002] gi|306782715|ref|ZP_07421037.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis SUMu003] gi|306791639|ref|ZP_07429941.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis SUMu005] 15 more sequence titles Length=525 Score = 1053 bits (2724), Expect = 0.0, Method: Compositional matrix adjust. Identities = 524/525 (99%), Positives = 525/525 (100%), Gaps = 0/525 (0%) Query 16 VLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDN 75 +LDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDN Sbjct 1 MLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDN 60 Query 76 GPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALH 135 GPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALH Sbjct 61 GPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALH 120 Query 136 SIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFF 195 SIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFF Sbjct 121 SIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFF 180 Query 196 AVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEI 255 AVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEI Sbjct 181 AVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEI 240 Query 256 LTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQ 315 LTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQ Sbjct 241 LTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQ 300 Query 316 VYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFG 375 VYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFG Sbjct 301 VYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFG 360 Query 376 TLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNI 435 TLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNI Sbjct 361 TLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNI 420 Query 436 APDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRR 495 APDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRR Sbjct 421 APDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRR 480 Query 496 ESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 ESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG Sbjct 481 ESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 525 >gi|289764215|ref|ZP_06523593.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis GM 1503] gi|289711721|gb|EFD75737.1| fatty-acid-CoA ligase fadD10 [Mycobacterium tuberculosis GM 1503] Length=539 Score = 1027 bits (2655), Expect = 0.0, Method: Compositional matrix adjust. Identities = 525/540 (98%), Positives = 526/540 (98%), Gaps = 1/540 (0%) Query 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA Sbjct 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 Query 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 QSVSRGSRVLVISDNGPETYLS C K +LPIAAIERFCQITDPAAALVA Sbjct 61 QSVSRGSRVLVISDNGPETYLSCCVC-KARGDRRHGRRHLPIAAIERFCQITDPAAALVA 119 Query 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT Sbjct 120 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 179 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG Sbjct 180 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 239 Query 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA Sbjct 240 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 299 Query 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG Sbjct 300 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 359 Query 361 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 420 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI Sbjct 360 IGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYI 419 Query 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES Sbjct 420 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 479 Query 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG Sbjct 480 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 539 >gi|118619896|ref|YP_908228.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99] gi|118572006|gb|ABL06757.1| fatty-acid-CoA ligase FadD10 [Mycobacterium ulcerans Agy99] Length=531 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/525 (82%), Positives = 462/525 (88%), Gaps = 3/525 (0%) Query 9 MPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR 68 M LP+TVL+R+ EQA+++PEAIALRRCDGTSAL Y ELVAEV A LRAQS SRGSR Sbjct 1 MSDLPATVLERIIEQAQRRPEAIALRRCDGTSALPYGELVAEVDRYAGALRAQSASRGSR 60 Query 69 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS 128 VLVISDNGPETYL+VLACAKLGAIAVMADGNLP A I+RFCQITDP A L+APGSK+ SS Sbjct 61 VLVISDNGPETYLAVLACAKLGAIAVMADGNLPPATIDRFCQITDPVAVLIAPGSKVGSS 120 Query 129 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL 188 ++PE L +IP I VDI + T E HS D A G++DPLAMIFTSGTTGEPKAVL Sbjct 121 SLPEGLAAIPAIRVDIGSGTGEFAHSPDTDRPATEPGLGADDPLAMIFTSGTTGEPKAVL 180 Query 189 LANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN 248 LANRTFFAVPDIL+ EGLNWVTWV GETTYSPLPATHIGGLWWILTCLM GGLC+TGGEN Sbjct 181 LANRTFFAVPDILRNEGLNWVTWVDGETTYSPLPATHIGGLWWILTCLMRGGLCITGGEN 240 Query 249 TTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEA 308 T SL++IL +NAV TTCLVPTLLSKLVSELKSA TVPSLRL+GYGGSRAIAADVRFIEA Sbjct 241 TLSLMQILNSNAVNTTCLVPTLLSKLVSELKSAATTVPSLRLLGYGGSRAIAADVRFIEA 300 Query 309 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAA---TDGIGPTA 365 TGVRTAQVYGLSETGCTALCLPTDDGSI KIEAGAVGRPYPGV+VYLAA DG GP A Sbjct 301 TGVRTAQVYGLSETGCTALCLPTDDGSIAKIEAGAVGRPYPGVEVYLAADDEADGAGPNA 360 Query 366 PGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSS 425 PGAGPSASFGTLWIKSPANMLGYW+NP+RT EVLIDGWVNTGDLLER EDGFFYIKGRSS Sbjct 361 PGAGPSASFGTLWIKSPANMLGYWSNPQRTQEVLIDGWVNTGDLLERHEDGFFYIKGRSS 420 Query 426 EMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARAL 485 EMII GGVNIAPDEVDRIAEGV GVREAAC+EIPD EFGALVGLAVVA+ ++D SAAR L Sbjct 421 EMIISGGVNIAPDEVDRIAEGVPGVREAACFEIPDPEFGALVGLAVVAATDVDASAARKL 480 Query 486 KHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAAT 530 KHTIAA +RRESE +ARPSTIVIV++IPRTQSGKVMR SLA AA Sbjct 481 KHTIAAHYRRESESVARPSTIVIVSEIPRTQSGKVMRTSLATAAN 525 >gi|183980290|ref|YP_001848581.1| fatty-acid-CoA ligase FadD10 [Mycobacterium marinum M] gi|183173616|gb|ACC38726.1| fatty-acid-CoA ligase FadD10 [Mycobacterium marinum M] Length=531 Score = 856 bits (2211), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/525 (82%), Positives = 461/525 (88%), Gaps = 3/525 (0%) Query 9 MPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR 68 M LP+TVL+R+ EQA+++PEAIALRRCDGTSAL Y EL AEV A LRAQS SRGSR Sbjct 1 MSDLPATVLERIIEQAQRRPEAIALRRCDGTSALPYSELAAEVDRYAGALRAQSASRGSR 60 Query 69 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS 128 VLVISDNGPETYL+VLACAKLGAIAVMADGNLP A I+RFCQITDP A L+APGSK+ SS Sbjct 61 VLVISDNGPETYLAVLACAKLGAIAVMADGNLPPATIDRFCQITDPVAVLIAPGSKVGSS 120 Query 129 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL 188 ++PE L +IP I VDI + T E HS D A G++DPLAMIFTSGTTGEPKAVL Sbjct 121 SLPEGLAAIPAIRVDIGSGTGEFAHSPDTDRPATEPGLGADDPLAMIFTSGTTGEPKAVL 180 Query 189 LANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN 248 LANRTFFAVPDIL+ EGLNWVTWV GETTYSPLPATHIGGLWWILTCLM GGLC+TGGEN Sbjct 181 LANRTFFAVPDILRNEGLNWVTWVDGETTYSPLPATHIGGLWWILTCLMRGGLCITGGEN 240 Query 249 TTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEA 308 T SL++IL +NAV TTCLVPTLLSKLVSELKSA TVPSLRL+GYGGSRAIAADVRFIEA Sbjct 241 TPSLMQILNSNAVNTTCLVPTLLSKLVSELKSAATTVPSLRLLGYGGSRAIAADVRFIEA 300 Query 309 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAA---TDGIGPTA 365 TGVRTAQVYGLSETGCTALCLPTDD SI KIEAGAVGRPYPGV+VYLAA DG GP A Sbjct 301 TGVRTAQVYGLSETGCTALCLPTDDDSIAKIEAGAVGRPYPGVEVYLAADDEADGAGPNA 360 Query 366 PGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSS 425 PGAGPSASFGTLWIKSPANMLGYW+NP+RT EVLIDGWVNTGDLLER EDGFFYIKGRSS Sbjct 361 PGAGPSASFGTLWIKSPANMLGYWSNPQRTQEVLIDGWVNTGDLLERHEDGFFYIKGRSS 420 Query 426 EMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARAL 485 EMII GGVNIAPDEVDRIAEGV GVREAAC+EIPD EFGALVGLAVVA+ ++D SAAR L Sbjct 421 EMIISGGVNIAPDEVDRIAEGVPGVREAACFEIPDPEFGALVGLAVVAATDMDASAARKL 480 Query 486 KHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAAT 530 KHTIAA +RRESE +ARPSTIVIV++IPRTQSGKVMR SLAAAA Sbjct 481 KHTIAAHYRRESESVARPSTIVIVSEIPRTQSGKVMRTSLAAAAN 525 >gi|15828082|ref|NP_302345.1| acyl-CoA synthetase [Mycobacterium leprae TN] gi|221230559|ref|YP_002503975.1| acyl-CoA synthetase [Mycobacterium leprae Br4923] gi|559909|emb|CAA86360.1| long chain fatty acid-coA ligase [Mycobacterium leprae] gi|13093636|emb|CAC30949.1| acyl-CoA synthase [Mycobacterium leprae] gi|219933666|emb|CAR72091.1| acyl-CoA synthase [Mycobacterium leprae Br4923] Length=532 Score = 797 bits (2059), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/531 (75%), Positives = 439/531 (83%), Gaps = 0/531 (0%) Query 9 MPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR 68 M LP TVL+R+ +QA ++PEAIALRR DGTS LRY +LVAEV GLAA L AQSVS+ SR Sbjct 1 MSHLPPTVLERILKQAHERPEAIALRRSDGTSELRYGQLVAEVNGLAAHLSAQSVSQRSR 60 Query 69 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS 128 VLVISDNGPETYLSVLACAKLGAIAVM DGNLP A I RF +I DP+A LVA ++ SS Sbjct 61 VLVISDNGPETYLSVLACAKLGAIAVMVDGNLPPATISRFSEICDPSAVLVARECRIDSS 120 Query 129 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL 188 ++PE LHSIP I V+ A S SLD LAGN + G++DPLAM FTSGTTGEPKAVL Sbjct 121 SLPEILHSIPAITVNTTADATYSACSLDIDYLAGNLNYGTDDPLAMTFTSGTTGEPKAVL 180 Query 189 LANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN 248 L NRTFFA+PDIL+++GL W+ WVV ETTYSPL ATHIGGLWWIL CLMHGGLC+TGGE+ Sbjct 181 LPNRTFFAIPDILREKGLAWIDWVVNETTYSPLSATHIGGLWWILNCLMHGGLCITGGEH 240 Query 249 TTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEA 308 T+SL E+L N VATTCLVPTLLSKLV ELK + P LRL+ YGGSR IAADVRFIEA Sbjct 241 TSSLTEVLNANKVATTCLVPTLLSKLVYELKFGDVVTPPLRLIVYGGSRVIAADVRFIEA 300 Query 309 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGA 368 GVRTAQ YGLSETGCTALCLPTD+GSI KIEAGAVGRPYPGV+VYLA +G GPT Sbjct 301 AGVRTAQFYGLSETGCTALCLPTDNGSISKIEAGAVGRPYPGVEVYLADPNGGGPTVADT 360 Query 369 GPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMI 428 SASFGTLWIKSPANMLGYWNNPERT E+L+DGWVNTGDL+ERREDGFFYIKGRSSEMI Sbjct 361 ASSASFGTLWIKSPANMLGYWNNPERTREILVDGWVNTGDLVERREDGFFYIKGRSSEMI 420 Query 429 ICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHT 488 + GGVNI PDEVDRIAE VSGV EAACYEIPD FGALVGLAV+ SAEL+ES A LK Sbjct 421 VSGGVNIVPDEVDRIAESVSGVGEAACYEIPDAHFGALVGLAVIPSAELNESTAIELKRR 480 Query 489 IAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVR 539 IAAR+RRESE MARPS IVIV DIPRTQSGKV+RA+LAAA ++ +VVR Sbjct 481 IAARYRRESESMARPSKIVIVADIPRTQSGKVIRATLAAALNGEQLGMVVR 531 >gi|308394434|ref|ZP_07491679.2| putative AMP-binding enzyme [Mycobacterium tuberculosis SUMu012] gi|308367704|gb|EFP56555.1| putative AMP-binding enzyme [Mycobacterium tuberculosis SUMu012] Length=371 Score = 734 bits (1896), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/365 (100%), Positives = 365/365 (100%), Gaps = 0/365 (0%) Query 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA Sbjct 1 MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRA 60 Query 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA Sbjct 61 QSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVA 120 Query 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT Sbjct 121 PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGT 180 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG Sbjct 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 Query 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA Sbjct 241 LCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 Query 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG Sbjct 301 ADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDG 360 Query 361 IGPTA 365 IGPTA Sbjct 361 IGPTA 365 >gi|317506388|ref|ZP_07964197.1| AMP-binding enzyme [Segniliparus rugosus ATCC BAA-974] gi|316255317|gb|EFV14578.1| AMP-binding enzyme [Segniliparus rugosus ATCC BAA-974] Length=529 Score = 696 bits (1797), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/526 (69%), Positives = 408/526 (78%), Gaps = 3/526 (0%) Query 15 TVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISD 74 TV +R+ QA Q+P+A+ALRR DGT LRY ELV V LA +L A SV+R SRV+V+SD Sbjct 7 TVWERICAQALQRPDAVALRRADGTGELRYAELVRAVERLAEELGAASVARESRVVVLSD 66 Query 75 NGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEAL 134 NGPETYL+VLACA+LG+IAVM DG LP A + RFCQI PAA LV G+ + E Sbjct 67 NGPETYLAVLACARLGSIAVMVDGTLPPATVGRFCQIAGPAAVLVPSGAAAGAVWSAEDG 126 Query 135 HSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTF 194 IP IAV +E + G D G +DPLAMIFTSGTTGEPKAVLLANRTF Sbjct 127 GPIPTIAV---GSGEAAERACAPDCGKGLPDLGPDDPLAMIFTSGTTGEPKAVLLANRTF 183 Query 195 FAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLE 254 FAVPDILQ GL+W+ W GE YSPLPATHIGGLWWILTCL +G CVTGGE ++SL E Sbjct 184 FAVPDILQGAGLSWIEWTAGEFAYSPLPATHIGGLWWILTCLANGVSCVTGGEGSSSLAE 243 Query 255 ILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTA 314 IL N VAT CLVPTLL++LV+ELK+ A VPSLR VGYGGSRAI DVRFIEA GVRTA Sbjct 244 ILNANEVATVCLVPTLLARLVAELKATGAEVPSLRFVGYGGSRAIPDDVRFIEAAGVRTA 303 Query 315 QVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASF 374 QV+GLSETGCTALCLPTD+ S+ +IE GAVGRPYPGV+VYLAA++ P G+ PSASF Sbjct 304 QVFGLSETGCTALCLPTDEDSLSRIEEGAVGRPYPGVEVYLAASEDCAPALAGSKPSASF 363 Query 375 GTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVN 434 GTLWIKSPANMLGYWNNPERT E L+DGWVNTGDL+ERR DGFFYIKGRSSE+II GGVN Sbjct 364 GTLWIKSPANMLGYWNNPERTRETLVDGWVNTGDLMERRADGFFYIKGRSSELIISGGVN 423 Query 435 IAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFR 494 + PDEVDRIAE V GVREAACYEIPD EFGALVGLAVV S LD + A LK +AAR+R Sbjct 424 VVPDEVDRIAERVKGVREAACYEIPDPEFGALVGLAVVPSEALDAAGAAELKRAVAARYR 483 Query 495 RESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG 540 RESE MARPS I +V DIPRT+SGKVMRA+LAAA ++A VV G Sbjct 484 RESESMARPSAIALVADIPRTKSGKVMRAALAAALRGERAEAVVGG 529 >gi|169627764|ref|YP_001701413.1| acyl-CoA synthetase [Mycobacterium abscessus ATCC 19977] gi|169239731|emb|CAM60759.1| Putative long chain fatty acid-coA ligase [Mycobacterium abscessus] Length=468 Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/499 (66%), Positives = 374/499 (75%), Gaps = 35/499 (7%) Query 42 LRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLP 101 + Y EL+ V LAA L A SV+ GSRV+V+SDNGP+TYLSVLACA+LGAIAVM D +LP Sbjct 1 MSYGELIGAVEDLAATLEAGSVTHGSRVVVLSDNGPQTYLSVLACARLGAIAVMVDDSLP 60 Query 102 IAAIERFCQITDPAAALVAPGSKMASS----AVPEALHSIPVIAVDIAAVTRESEHSLDA 157 A + RF +IT PAA + G + + A P+A Sbjct 61 AATVARFSEITRPAAIIPNEGGGVGAENGERAYPKA------------------------ 96 Query 158 ASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETT 217 D G+++ LAMIFTSGTTGEPKAVLL NRTFFA+PDIL+ EGL W+ WV GETT Sbjct 97 -----QPDSGADEALAMIFTSGTTGEPKAVLLPNRTFFAIPDILRAEGLRWIDWVAGETT 151 Query 218 YSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSE 277 YSPLPATHIGGLWWIL LMHG C+TGGE SL E+L N VAT CLVPTLL++LVSE Sbjct 152 YSPLPATHIGGLWWILNGLMHGASCITGGEQGASLRELLVDNEVATACLVPTLLTRLVSE 211 Query 278 LKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIV 337 LK VP+LR + YGGSRAIAADVRFIEA GVRTAQVYGLSETGCTALCLPTD SI Sbjct 212 LKLTGTDVPALRFIAYGGSRAIAADVRFIEAAGVRTAQVYGLSETGCTALCLPTDSESIS 271 Query 338 KIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAE 397 +IE GAVGRPYPGV YL+ G PT SAS+GTLWIKSPANMLGYW +PERT E Sbjct 272 RIEQGAVGRPYPGVQTYLSPEGGGDPTT--GAESASYGTLWIKSPANMLGYWGSPERTGE 329 Query 398 VLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYE 457 VL +GWVNTGDL+ERR DGFFYI+GRSSEMII GGVN+ PDEVDRIAE ++GVREAACYE Sbjct 330 VLAEGWVNTGDLVERRADGFFYIRGRSSEMIISGGVNVVPDEVDRIAEDIAGVREAACYE 389 Query 458 IPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQS 517 IPDEEFGALVGLAVVA+ ELD + ALK IAAR+RRESE MARPSTIV+V DIPRT+S Sbjct 390 IPDEEFGALVGLAVVATTELDGAGTAALKQRIAARYRRESESMARPSTIVLVEDIPRTKS 449 Query 518 GKVMRASLAAAATADKARV 536 GKVMR++L+A+ +ARV Sbjct 450 GKVMRSALSASLNGARARV 468 >gi|307082567|ref|ZP_07491680.1| hypothetical protein TMLG_00838 [Mycobacterium tuberculosis SUMu012] gi|308367689|gb|EFP56540.1| hypothetical protein TMLG_00838 [Mycobacterium tuberculosis SUMu012] Length=305 Score = 612 bits (1578), Expect = 6e-173, Method: Compositional matrix adjust. Identities = 304/305 (99%), Positives = 305/305 (100%), Gaps = 0/305 (0%) Query 236 LMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGG 295 +MHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGG Sbjct 1 MMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGG 60 Query 296 SRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYL 355 SRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYL Sbjct 61 SRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYL 120 Query 356 AATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERRED 415 AATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERRED Sbjct 121 AATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERRED 180 Query 416 GFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASA 475 GFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASA Sbjct 181 GFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASA 240 Query 476 ELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKAR 535 ELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKAR Sbjct 241 ELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKAR 300 Query 536 VVVRG 540 VVVRG Sbjct 301 VVVRG 305 >gi|297153933|gb|ADI03645.1| long-chain-fatty-acid--CoA ligase [Streptomyces bingchenggensis BCW-1] Length=528 Score = 243 bits (621), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 173/546 (32%), Positives = 253/546 (47%), Gaps = 53/546 (9%) Query 15 TVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISD 74 T+ D + A ++P+ AL G+ + Y+EL A L A V RGSR+ + Sbjct 12 TLQDSLARHAAERPDHPAL--VCGSVQVTYQELDRRSDRTAQALTASGVRRGSRIAHFAA 69 Query 75 NGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALV------APGSKMASS 128 + + VLACAK GA+ V D L A + + D L+ AP + A Sbjct 70 DSERFHEIVLACAKTGAVLVPIDWRLTTAEVTHI--LRDSGTELLFFGPALAPLVREARP 127 Query 129 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDP---------------LA 173 A+P+ H++P LD A AD D + Sbjct 128 ALPKLQHTVP----------------LDTAGFEAWADDRPFDTGFTAPAEADADADTEVV 171 Query 174 MIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWIL 233 I+TSGTTG PK V+LA R+FFAV +L + GL W+ W + + +P HIGGLWW + Sbjct 172 QIYTSGTTGAPKGVVLAQRSFFAVAGMLAEHGLEWIDWRADDRSLVCVPGFHIGGLWWAM 231 Query 234 TCLMHGGLCVT-GGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVG 292 L G V ++ ++++ + T C+VP ++ ++ E SLR V Sbjct 232 QGLNAGVTNVLLPAFDSLRAVDLIREAGITTACMVPAMMRMILDEPNVGRPDFASLRKVV 291 Query 293 YGGSRAIAADVRF-IEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGV 351 YGGS +R ++ AQ+YGL+ETG TA+CLP + A G PYPGV Sbjct 292 YGGSPISDTLLRRGLDIFDCELAQIYGLTETGNTAVCLPPSEHRPGSPRLAAAGLPYPGV 351 Query 352 DVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLE 411 + + + G P+ G +W+ +PA M GYWN P+ T L+DGW+ TGD Sbjct 352 RMRIVDSQG------DDVPTGEIGQVWLHTPARMAGYWNLPDATERTLVDGWIVTGDAGY 405 Query 412 RREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAV 471 R EDG+ YI+ R ++ II GG N+ P EV+ S + EAA P+ G V + Sbjct 406 RDEDGYLYIRDRITDTIIVGGENVYPAEVENALCRHSAIAEAAVVGAPNSASGEEVRAYI 465 Query 472 VASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATA 531 V D AA+ L ++ + R P+T ++ +PR SGK++R L A Sbjct 466 VLRQGHDVPAAQELTRFLSGQLAR----FKIPATYQVIDVVPRNPSGKILRRKLREQLWA 521 Query 532 DKARVV 537 D R V Sbjct 522 DSDRKV 527 >gi|302527900|ref|ZP_07280242.1| dicarboxylate-CoA ligase PimA [Streptomyces sp. AA4] gi|302436795|gb|EFL08611.1| dicarboxylate-CoA ligase PimA [Streptomyces sp. AA4] Length=531 Score = 235 bits (599), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 178/528 (34%), Positives = 258/528 (49%), Gaps = 35/528 (6%) Query 23 QARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLS 82 AR +P+ +A+R C+ + Y +L +A LRA G+RV+ + + Y Sbjct 25 HARNRPDQVAIR-CEDRE-VTYAQLHRGSNRIARALRAAGAGPGARVVYLGRDSEHYYRL 82 Query 83 VLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAV 142 + ACAK A V+ N + A E + D A LV + + V EA + Sbjct 83 LFACAK--AETVLVPVNWRLTAGETEHVLRDSGAHLVF-AERDFLTVVKEAGKDLAAPPE 139 Query 143 DIAAVTRESEHSLD-------AASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFF 195 IA + + LD A + G AD + P+ ++TSGTTG PK V+LA+R+F+ Sbjct 140 VIAVTASDPDGGLDDWARDASAEDIDGTAD--PDRPIVQMYTSGTTGLPKGVVLAHRSFY 197 Query 196 AVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSL--L 253 AV D L L+W+ W G+ + +P HIGGLWW L H G+ TS + Sbjct 198 AVRDALAGADLDWIDWREGDVSLLGVPGFHIGGLWWALQGF-HAGITNVALRTFTSADAV 256 Query 254 EILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGS----RAIAADVRFIEAT 309 ++ + V T C+VP +L +++E +A S+R V YGGS R +A IE Sbjct 257 RLVREHRVTTMCVVPAMLQMMLAERAVTDADFASVRKVVYGGSPIGERLLA---EAIERI 313 Query 310 GVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAG 369 G AQ+YGL+E+G TA+CLP + A GRPYPG + + D P Sbjct 314 GCEFAQIYGLTESGNTAVCLPPSEHVAGGPRMTAAGRPYPGFAL-MIKDDAGNPL----- 367 Query 370 PSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMII 429 P+ G +WI++P ++L YW PE TAE L+DGW+ TGD E+GF +I R + II Sbjct 368 PAREIGEVWIRTPGHLLEYWGQPEATAETLVDGWLRTGDAGYLDEEGFLFICDRIKDTII 427 Query 430 CGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTI 489 G N+ P EV+ V EAA +PDE +G V A V A E++AR L + Sbjct 428 VAGENVYPAEVENALGKHPAVTEAAVVGVPDERWGEAVH-AFVVLAPGAEASARELTVFL 486 Query 490 AARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 + R P++ V +PR SGK++R L + D AR V Sbjct 487 SGRL----AGFKTPTSYEYVDRLPRNASGKILRRQLRDSFWQDAARKV 530 >gi|29827146|ref|NP_821780.1| long-chain-fatty-acid--CoA ligase [Streptomyces avermitilis MA-4680] gi|15824221|dbj|BAB69379.1| long-chain fatty acid--CoA ligase [Streptomyces avermitilis] gi|29604244|dbj|BAC68315.1| putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase [Streptomyces avermitilis MA-4680] Length=518 Score = 216 bits (551), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 165/540 (31%), Positives = 251/540 (47%), Gaps = 41/540 (7%) Query 10 PQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRV 69 P+L + V F AR QP A+ +G + + Y +L E +A ++A ++ G RV Sbjct 7 PELQTLVQTTSF-HARNQPTTPAVL-FEGRT-VTYEQLHRESNRIAHAVQAAGLTPGDRV 63 Query 70 LVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALV------APGS 123 + Y + CAK G + V + L + + D L+ P Sbjct 64 AYLGKESEHYYEILFGCAKSGTVLVPVNWRLTAPEVSHILR--DSGTRLLFLEEEFGPIV 121 Query 124 KMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGE 183 + +A PE V+ + V ++ H + D P+A ++TSGTTG Sbjct 122 EKMPTAPPET-----VVGLGEPFVAWKASHPDTDPTPHVTPDT----PVAQLYTSGTTGL 172 Query 184 PKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCV 243 PK V+LA+R+FFA+ D L EGL+W+ W G+ +P HIGGLWW G V Sbjct 173 PKGVVLAHRSFFAIRDALASEGLDWIDWRAGDIALIGIPGFHIGGLWWATQNFNAGTTIV 232 Query 244 -TGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAAD 302 ++++ + T C+VP +L +++E + + +LR YGGS A Sbjct 233 AMRAFAARQAVDLIRDLGITTACVVPAMLRMMLTEPRVSAKDFTTLRKTVYGGSPISEAL 292 Query 303 VR-FIEATGVRTAQVYGLSETGCTALCLP----TDDGSIVKIEAGAVGRPYPGVDVYLAA 357 + + AQ+YGL+ETG TA+CLP GS+++ A GRPYPGV + Sbjct 293 LEESLAVLDCEFAQIYGLTETGNTAVCLPPAAHVPGGSLMQ----AAGRPYPGVGSKV-- 346 Query 358 TDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGF 417 DG G P + G + + +PA+M+ YW P +TAE L+DGW++TGD EDG+ Sbjct 347 IDGEGRELP----PGAVGEVCLATPAHMVEYWGLPGKTAETLVDGWIHTGDAGYIDEDGY 402 Query 418 FYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAEL 477 +I+ R + I+ G N+ P E++ + E GV EA PDE +G V A V A Sbjct 403 IFIRDRIKDAILVAGENVYPAEIENVLEHHPGVAEAVVVGAPDERWGEYVH-AFVVPAPG 461 Query 478 DESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 + R L + R P+ + +PR SGK++R L D AR V Sbjct 462 QRPSPRDLHTFLVPRLAS----FKLPARYEFIESVPRNPSGKILRRELRDRFWDDSARKV 517 >gi|238632107|gb|ACR50792.1| putative acyl-CoA synthase [Streptomyces longisporoflavus] Length=520 Score = 213 bits (541), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 163/513 (32%), Positives = 229/513 (45%), Gaps = 28/513 (5%) Query 22 EQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYL 81 A +P+ +A+R C G + + EL A L A+ + GSRV ++ + Y Sbjct 23 HHAETRPDRVAVR-C-GDREVTFLELYHRGNRTAHALLAEGLVPGSRVGYLAKDTEHYYD 80 Query 82 SVLACAKLGAIAVMADGNLPIAAIERFCQ-------ITDPAAALVAPGSKMASSAVPEAL 134 +LACA G + V D L IE + +T+ V G ++ S L Sbjct 81 LLLACAAGGTVLVPVDPRLTPGEIEHVLRDSGTELLVTEEEKLPVVEGLELGS------L 134 Query 135 HSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTF 194 ++ + D A D A G+ PLA ++TSGTTG PK V+L TF Sbjct 135 RTVLALDDDGARPGGFLHWKADRPDTPPGAPAGARRPLAQMYTSGTTGRPKGVVLGQHTF 194 Query 195 FAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTG-GENTTSLL 253 +AV D+L + GL+W+ W + LP HIGG WW + G V G + L Sbjct 195 WAVNDLLARHGLDWIDWREEDRLLQVLPGHHIGGPWWFMQGFRAGATHVVAQGFDARRTL 254 Query 254 EILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV-RFIEATGVR 312 +L + TT +VP++L L++E LR V YGG+ + + ++ G Sbjct 255 ALLAEGGITTTLMVPSMLRILLAEPGVGPGHFAGLRKVVYGGAPIPEPLLEQCLDVMGCE 314 Query 313 TAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSA 372 AQ+YGL+ET +A+CLP D AVGRPYPGV V G P PG Sbjct 315 FAQIYGLTETCASAVCLPPADHVPGNPRLKAVGRPYPGVAVQAVDRSG-DPLPPG----- 368 Query 373 SFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGG 432 G + I +PA M GYW PE T L DGW+ TGD EDG+ Y+ R ++I+ G Sbjct 369 RVGEIRIDTPAVMTGYWQRPEETELALADGWLRTGDAGHVDEDGYVYLHDRIKDVILVAG 428 Query 433 VNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAAR 492 N+ P EV+ V EAA PD+ G V VV A R + Sbjct 429 ENVYPAEVENALSKHPAVAEAAVVATPDQVRGEAVRACVVVRA-----GERLTARELMLF 483 Query 493 FRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 R P P+ V +PR +GK++R L Sbjct 484 LRELLAPYKIPTAYTFVDSLPRNAAGKILRREL 516 >gi|261855561|ref|YP_003262844.1| AMP-dependent synthetase and ligase [Halothiobacillus neapolitanus c2] gi|261836030|gb|ACX95797.1| AMP-dependent synthetase and ligase [Halothiobacillus neapolitanus c2] Length=530 Score = 204 bits (520), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 138/391 (36%), Positives = 195/391 (50%), Gaps = 23/391 (5%) Query 153 HSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWV 212 HS+ S+ D E +I+TSGTTG PK V L ++ FF + + L K+ L W+ W Sbjct 157 HSVAKESVLPACD--PERTFCLIYTSGTTGLPKGVCLPHKAFFQIREALIKQDLKWLDWR 214 Query 213 VGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSL-LEILTTNAVATTCLVPTLL 271 + +P HIGGLWW L C G V + L L + V T C+VP+++ Sbjct 215 QSDRCLVGIPGFHIGGLWWALQCFSSGASIVVLPKFEPQLCLTAMLDCGVTTACMVPSMI 274 Query 272 SKLVSELKSANATVPSLRLVGYGG---SRAIAADVRFIEATGVRTAQVYGLSETGCTALC 328 + L+ ++ +A + LR + YGG S A+ +R I G AQ+YGLSETG TA+C Sbjct 275 NLLLDVIEQNDAKLLKLRKIVYGGGPISEALL--MRGISVLGCDFAQIYGLSETGNTAVC 332 Query 329 LPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGY 388 L D A GRPYPGV + + TDG P G + IK+PA M+ Y Sbjct 333 LDPDSHLSEPSLLTAAGRPYPGVKLKIIDTDG------KVLPMGEVGEVCIKTPARMIEY 386 Query 389 WNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVS 448 W P+ T+ L DGW++TGD E G+ +I R ++I+ GG I P EV+ + S Sbjct 387 WGLPDATSATLQDGWIHTGDAGYLNESGYLFICDRIKDVIVTGGEKIFPAEVENVVSSFS 446 Query 449 GVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMA--RPSTI 506 V E A IP+E +G + VV E A+ T +F ES A +P+ I Sbjct 447 TVHECAVIGIPNEVWGEVPICLVVPKPE------SAVNITDLFKF-LESRLAAYKKPTQI 499 Query 507 VIVTDIPRTQSGKVMRASLAAAATADKARVV 537 V +PR SGK++R +L A + R V Sbjct 500 HCVDSLPRNPSGKLLRRALRDAFWTGRKRNV 530 >gi|329940134|ref|ZP_08289416.1| substrate-CoA ligase [Streptomyces griseoaurantiacus M045] gi|329300960|gb|EGG44856.1| substrate-CoA ligase [Streptomyces griseoaurantiacus M045] Length=504 Score = 201 bits (512), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 168/525 (32%), Positives = 250/525 (48%), Gaps = 28/525 (5%) Query 14 STVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVIS 73 +T+ R+ A ++P AL G YREL AA L A +V G+RV + Sbjct 2 NTLTARLAAVAGERPHHPAL--VCGEERRTYRELWENSARWAAVLGAHAVEPGTRVGYLG 59 Query 74 DNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEA 133 + ACA+ GA+ + +E + D A ++ A +A EA Sbjct 60 RDSAFLVELFYACARTGAVFLPIGSRFTTPEVEHL--LDDSGATVLFVQRDFAEAA--EA 115 Query 134 LHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRT 193 L + A V E + A +G+ DP+ +TSGTTG PK V+LA+R+ Sbjct 116 LTTS-------ATVLIAEEATGAGDGAGAPAAEGAGDPVVQFYTSGTTGVPKGVVLAHRS 168 Query 194 FFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG-LCVTGGENTTSL 252 FFAV + L G +WV ++ G+TT +P H+GGLWW++ L G + V + + Sbjct 169 FFAVAEALAAAGEDWVDFLPGDTTLVGVPCWHVGGLWWVVQALNAGATVVVMPTLSAAGV 228 Query 253 LEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV--RFIEATG 310 L ++ + V T C P LLS ++ E + +LR + YG + I+ + R IE G Sbjct 229 LALVPRHGVTTMCAPPALLSLILDEPGRRPEALRTLRKIVYGAA-PISQTLLRRCIEEIG 287 Query 311 VRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGP 370 AQ+YGL++TG TA+CLP + A GRPYPG +V + G A P Sbjct 288 CALAQIYGLTKTGNTAVCLPPAEHYPGNPLLHAAGRPYPGFEVKIVDRSG------AALP 341 Query 371 SASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIIC 430 + G + +++PA M+ YW PE TAE L DGW++TGD+ E G+ +++ R MII Sbjct 342 RGAAGEVCLRTPARMVEYWGRPEATAETLRDGWIHTGDVGHLDEAGYVHLRDRVKNMIIR 401 Query 431 GGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIA 490 G N+ P EV+ V +AA IPD+ +G V LA V A+ +AR L+ + Sbjct 402 AGENVYPAEVENALHRSPAVADAAVIGIPDDRWGEAV-LACVVPAQGHRVSARELRLFLR 460 Query 491 ARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKAR 535 P+ V V IPR GK++ L A + R Sbjct 461 E----LLADYKIPTRFVAVEAIPRNGVGKILHRELRAPYWEGRER 501 >gi|29828821|ref|NP_823455.1| long-chain-fatty-acid--CoA ligase [Streptomyces avermitilis MA-4680] gi|29605926|dbj|BAC69990.1| putative acyl-CoA synthetase [Streptomyces avermitilis MA-4680] Length=534 Score = 197 bits (500), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 145/496 (30%), Positives = 222/496 (45%), Gaps = 35/496 (7%) Query 44 YRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIA 103 Y +L E A LR V RG RV + YL +LACAK GA+ V + L Sbjct 37 YGKLHRESNRAAHALRVSGVQRGDRVAYLGRESENYYLVILACAKAGAVLVPVNWRLTPD 96 Query 104 AIERFCQITDPAAALVAPGSKMASSA------VPEALHSIPVIAVDIAAVTRESEHSLDA 157 ++ + D A LV + ++A +PE H++ + I E E + A Sbjct 97 EVDHI--LRDSGATLVFVDDEFWATATKVRPHLPE-FHTM----IRIDGTDAEGEPARGA 149 Query 158 ASLAGNADQ---------GSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNW 208 A ADQ G +D + I+TSGTTG PK +LA+R+FF +P ++ + W Sbjct 150 GLPAWYADQPDADLEPGTGPDDAVVQIYTSGTTGLPKGAVLAHRSFFTLPQAMRDHDVAW 209 Query 209 VTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGE-NTTSLLEILTTNAVATTCLV 267 + W+ + LP I G+ W + GG V + + + ++ T+ V TT Sbjct 210 IDWLPDDVALISLPGFGIAGIGWFMHTFNAGGTSVIMPQFDPQEAVRLIRTHRVTTTFAA 269 Query 268 PTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVR-FIEATGVRTAQVYGLSETGCTA 326 P +L + E + SLR + YG + ++ +E AQ+Y +ETG A Sbjct 270 PAMLQMMAGERTAGPDAFVSLRKICYGAAPMSETLLKQCLETFDCEFAQIYASTETGSVA 329 Query 327 LCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANML 386 +CLP + +VG+P PG +V + DG P + G + +++P+ ML Sbjct 330 VCLPPEAHHPGSTVLESVGKPCPGNEVKVVGPDG------AELPPGAIGQICVRAPSRML 383 Query 387 GYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEG 446 GYWN PE T L+ W++ GD EDG+ Y+ R ++ II G NI P EV++ Sbjct 384 GYWNLPEATGRTLVGEWLHMGDAGYLDEDGYIYLCDRMNDTIIVAGQNIYPAEVEKALAA 443 Query 447 VSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTI 506 V ++A +PD +G V AVV A+A + R P Sbjct 444 HPAVADSAVVGLPDPRWGEAVHAAVVL-----RPGAQASPRELLLSLRGHLADYKIPGAY 498 Query 507 VIVTDIPRTQSGKVMR 522 V +PR SGK++R Sbjct 499 HFVDTLPRNPSGKILR 514 >gi|310818957|ref|YP_003951315.1| AMP-dependent synthetase and ligase [Stigmatella aurantiaca DW4/3-1] gi|309392029|gb|ADO69488.1| AMP-dependent synthetase and ligase [Stigmatella aurantiaca DW4/3-1] Length=525 Score = 196 bits (499), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 153/507 (31%), Positives = 227/507 (45%), Gaps = 27/507 (5%) Query 42 LRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLP 101 L Y L A L + + G RV ++ + + + AK A+ V + L Sbjct 34 LSYEALEHRSNQAAHALLREGIRPGERVAILGKESLDALVLLFGAAKAHAVYVGLNWRL- 92 Query 102 IAAIERFCQITDPAAALVAPGSKMASSAVPEALHSI--PVIAVDIAAVTRESEHSLDAAS 159 A E I + + A + + +++ VP + P+ V + A ++ + Sbjct 93 --APEELAYILEDSGARMLFVDEESAALVPRVFEKMRGPLPVVRVGA--KQDAPGTFSHW 148 Query 160 LAGNAD------QGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVV 213 AG AD +ED + ++TSGTTG PK V L +R+ A+ L+ G W+ W Sbjct 149 CAGAADTPLTETYDAEDVVVQLYTSGTTGRPKGVQLPHRSLLAIAHELEAHGERWIGWTE 208 Query 214 GETTYSPLPATHIGGLWWILTCLMHG-GLCVTGGENTTSLLEILTTNAVATTCLVPTLLS 272 + +P HIGGLWW++ L G V G ++L + V TC+VP ++ Sbjct 209 ASVSLLFVPTFHIGGLWWLVRGLALGCTQVVLRGFEPATILASIPRYRVTHTCMVPAMMQ 268 Query 273 KLVSELKSANATVPSLRLVGYGGS-RAIAADVRFIEATGVRTAQVYGLSETGCTALCL-P 330 L+SE + SL + YGG+ + A + G AQ+YG++ETG A+CL P Sbjct 269 ILLSEPGLQQTDLSSLEAIVYGGAPMSTALLEKGQRLLGCGFAQIYGMTETGNCAVCLRP 328 Query 331 TDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWN 390 D + A GRP+PGV V + G APGA G + + SPA M GYW Sbjct 329 EDHLGALPSRLRAAGRPFPGVKVRILDEQG-QEVAPGA-----IGQICLHSPARMAGYWR 382 Query 391 NPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGV 450 PE T + L+DGWV TGD +GF YI R +MII G NI P E++ + V Sbjct 383 QPEETRKTLVDGWVMTGDAGYVDAEGFVYICDRVKDMIISAGENIYPAEIENVIRSHPEV 442 Query 451 REAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIVT 510 + A +PDE +G V VV A L+HT R P ++ Sbjct 443 ADVAVIGVPDELWGEAVKALVVKQPGSHLRAGDILRHT-----RGALAEFKVPKSVEFTG 497 Query 511 DIPRTQSGKVMRASLAAAATADKARVV 537 +PR SGK+++A L + R V Sbjct 498 PLPRNASGKLLKAVLREPYWKGRERRV 524 >gi|124007603|ref|ZP_01692307.1| AMP-dependent synthetase and ligase [Microscilla marina ATCC 23134] gi|123986901|gb|EAY26666.1| AMP-dependent synthetase and ligase [Microscilla marina ATCC 23134] Length=525 Score = 194 bits (493), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 149/535 (28%), Positives = 247/535 (47%), Gaps = 42/535 (7%) Query 6 FQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSR 65 FQ +P L + +QA Q P IAL D Y +L +A L +S Sbjct 5 FQTLPDLSA-------KQASQIPNKIALIYED--ELYTYAQLEQNANRVAQGLLQLGLSP 55 Query 66 GSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSK- 124 +RV +++ + +Y + CAK + V+ N + A E + D ++ G + Sbjct 56 QTRVAILAKDSLASYEILFGCAK--SKTVLVTINWRLVAQEVLFILNDSQTEVLFVGKEF 113 Query 125 --MASSAVPEALHSIPVIAVDIAAVTRE--------SEHSLDAASLAGNADQGSEDPLAM 174 + P+ + +I+++ + E ++HS + +L D ED Sbjct 114 LPLIEQIKPDLQNIKTIISIEQPDASMEYRDYTSWKNQHSNQSPAL----DYLPEDVTVQ 169 Query 175 IFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILT 234 I+TSGTTG PK V LA+ +FF + +Q +G W+ +T LP HIGGLWW + Sbjct 170 IYTSGTTGLPKGVQLAHYSFFRLMKGMQAQGDAWMNLNAQDTLLLSLPMFHIGGLWWTIQ 229 Query 235 CLMHGGL-CVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGY 293 ++ GG V LE++ + +VP ++ ++E S++ Y Sbjct 230 GMIVGGRGAVLNTFVPWRALELIEQYQITKVAMVPAMIQFCMAEPTFDTTNFSSVQGFLY 289 Query 294 GGSRAIAADVRF-IEATGVRTAQVYGLSETGCTALCL-PTDDGSIVKIEAGAVGRPYPGV 351 GGS +R ++A Q+YG++ETG A+CL P D + A G+P PGV Sbjct 290 GGSPIAPTLLRQAMDALQCGFFQIYGMTETGNMAVCLRPEDHDFSNETRLKAAGKPLPGV 349 Query 352 DVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLE 411 +V + + G +A G + +KSP+ M+GYWN E T + L+DGW++TGD+ Sbjct 350 EVKITNSQGELLSA------HQIGEIHLKSPSRMIGYWNRDEATKKTLVDGWISTGDVGY 403 Query 412 RREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAV 471 + E+G+ ++ R +MII G N+ P E++ G+ E A IP E++G Sbjct 404 QDEEGYIFVCDRVKDMIIYAGENLFPVEIEAALSEHEGIEEVAVIGIPSEQWGE------ 457 Query 472 VASAELDESAARALKHTIAARFRRES-EPMARPSTIVIVTDIPRTQSGKVMRASL 525 + A + + +LK + F +E P ++ V +PR SGKV++ L Sbjct 458 IPKAFIVQKPGYSLKKKVILSFAKERMADFKVPRSVEFVDKLPRNPSGKVLKRVL 512 >gi|291442742|ref|ZP_06582132.1| acyl-CoA synthetase [Streptomyces ghanaensis ATCC 14672] gi|291345637|gb|EFE72593.1| acyl-CoA synthetase [Streptomyces ghanaensis ATCC 14672] Length=538 Score = 191 bits (484), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 146/483 (31%), Positives = 224/483 (47%), Gaps = 36/483 (7%) Query 63 VSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQ-------ITDPA 115 + RGSRV + YL+VLACAK GA+ V + L A +E + D Sbjct 60 IGRGSRVAYLGRESEHYYLTVLACAKAGAVIVPVNWRLTSAEVEHILRDSSAELLFLDEE 119 Query 116 AALVAPGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQ----GSEDP 171 VA G+ +A +P + + D + A D G +DP Sbjct 120 FQSVADGA-LAGPGLPSLRTVVRLDGTGQDGARDRGAGLRDWYARAPQTDTDPGTGPDDP 178 Query 172 LAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLN---WVTWVVGETTYSPLPATHIGG 228 + I+TSGTTG PK V++A+RTFF +P+ ++ G + W+ W + + LP I G Sbjct 179 VLQIYTSGTTGLPKGVVIAHRTFFTLPEAMRASGADPDDWIDWRADDVSLISLPGFGIAG 238 Query 229 LWWILTCLMHGGLCVTGGENTTS-LLEILTTNAVATTCLVPTLLSKLVSELKSANATVPS 287 + W L G V + + ++ + V T + PT+L ++ E + T S Sbjct 239 IGWFLHGFCAGATHVVMPMYVAAEAVRLIRAHGVTITFVAPTMLQMMLDERDATPETFAS 298 Query 288 LRLVGYGGSR-AIAADVRFIEATGVRTAQVYGLSETGCTALCLPTD----DGSIVKIEAG 342 LR + YG + + +R +E G + AQ+Y +E G A+CLP G ++K Sbjct 299 LRKIAYGAAPISEGLLLRSLETFGCQLAQIYASTEAGSVAVCLPPSAHKPGGPLLK---- 354 Query 343 AVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDG 402 A G+P PG ++ + DG P G + I++PA+M+GYWN PE TAE L+DG Sbjct 355 AAGKPCPGNEIKVVDRDG------NELPPGEIGQVCIRTPAHMVGYWNRPEATAEALVDG 408 Query 403 WVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEE 462 W+ GD EDG ++ R ++ II G NI P EV++ V +AA +PD+ Sbjct 409 WLRMGDAGYLDEDGHLFLCDRINDTIIVAGQNIYPAEVEKQLSEHPAVADAAVVGVPDDH 468 Query 463 FGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMR 522 +G V AVV E R L + R P+ ++ +PR SGK++R Sbjct 469 WGEAVHAAVVLRPGA-EVRPRQLLLFLRGRLADYKIPI----RYHVLDSLPRNPSGKILR 523 Query 523 ASL 525 S+ Sbjct 524 RSV 526 >gi|311896126|dbj|BAJ28534.1| putative long-chain fatty-acid--CoA ligase [Kitasatospora setae KM-6054] Length=533 Score = 184 bits (466), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 152/507 (30%), Positives = 226/507 (45%), Gaps = 42/507 (8%) Query 36 CDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVM 95 C+G YR + E A + A + GSRV + Y LACAK G + V Sbjct 26 CEG-RVTDYRRIDEESSRAARAILAAGLGTGSRVAYLGKESEHYYELALACAKAGTVLVP 84 Query 96 ADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSI-PVI-----AVDIAAVTR 149 + L E ++D AA L+ A A E + + P++ V++A Sbjct 85 VNWRLTAGEAEHI--LSDSAAELL-----FAEPAFGELVEKVRPLLPGLRQVVELAPPGE 137 Query 150 ESEHSLDAASLAGNADQ---GSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGL 206 AA A G +D + I+TSGTTG PK V+LA+R+FF +P + G+ Sbjct 138 SGGQRAWAAGFAATPPGTAGGPDDAVLQIYTSGTTGAPKGVVLAHRSFFTLPAAMAGAGV 197 Query 207 NWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGEN-------TTSLLEILTTN 259 W+ W+ + LP I G+ W MHG GG N + + ++ + Sbjct 198 AWIDWLPTDRNLISLPGFSIAGMGW----FMHG--FAAGGTNVVMRMFVSEEAVRLIAEH 251 Query 260 AVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV-RFIEATGVRTAQVYG 318 V TT P +L ++ E ++ A SLR V YG + A + R +E AQ+Y Sbjct 252 GVTTTFAAPAMLQMMIEERGASKAAFRSLRKVAYGAAPMSDALLGRCLELLDCEFAQIYA 311 Query 319 LSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLW 378 +ETG A+CLP +D + G+VGR PG L D G P + G + Sbjct 312 ATETGTVAVCLPPEDHWVGSPVLGSVGRACPGHR--LKVVDDAGEELP----PGAIGRVC 365 Query 379 IKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPD 438 + +PA MLGYW P TA+ + W+ GD EDG+ Y+ R ++ II G NI P Sbjct 366 VSTPARMLGYWGLPGATADAIDGEWLRMGDAGYLTEDGYLYLCDRINDTIIAAGQNIYPA 425 Query 439 EVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESE 498 EV++ +G V E+A +PDE +G V VV + L+H ++ R Sbjct 426 EVEKALDGHPAVAESAVLGVPDELWGDAVLACVVVRPGRAVTPRELLRH-LSGRL----A 480 Query 499 PMARPSTIVIVTDIPRTQSGKVMRASL 525 P+ V +PR +GK++R L Sbjct 481 DYKTPTRWEFVDAVPRNPTGKILRRVL 507 >gi|226312168|ref|YP_002772062.1| acyl-CoA synthetase [Brevibacillus brevis NBRC 100599] gi|226095116|dbj|BAH43558.1| probable O-succinylbenzoate--CoA ligase [Brevibacillus brevis NBRC 100599] Length=508 Score = 183 bits (464), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 158/532 (30%), Positives = 250/532 (47%), Gaps = 61/532 (11%) Query 22 EQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQ-SVSRGSRVLVISDNGPETY 80 ++AR P IA+ +L Y+++ ++ +A LR + V +G R+ ++S N E Sbjct 10 KRARITPTRIAV--IANEQSLTYQQMNEQIQRVANYLRHELQVKKGDRIGILSQNSLEYV 67 Query 81 LSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVI 140 L + A AKLGAIAV N+ + E Q D ++ + A++ E + + + Sbjct 68 LLLFAIAKLGAIAVPF--NIRLTPAELDYQFEDSGIRVLCAQPEFAATI--ELIKAKASV 123 Query 141 AVDIAAVTRESEHSLDAASLAG-----NADQGS-EDPLAMIFTSGTTGEPKAVLLANRTF 194 A I E S D S + +AD GS +DP + +TSGTTG+PK +L Sbjct 124 AHMIWLEPGELPWSQDGPSESSQHSRIDADDGSGDDPYIICYTSGTTGKPKGAVLTQENM 183 Query 195 F--AVPDI----LQKEGLNWVTWVVGETTYSPLPATHIGG--LWWILTCLMHGGLCVTGG 246 F +V ++ L E + V LP HIGG L+ T L G + V G Sbjct 184 FWNSVHNVAALDLTSEDCSIVL----------LPLFHIGGIGLFAFPTWLAGGRVVVAGK 233 Query 247 ENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFI 306 + ++++ T+ V VP + + A + S+R GG+ ++ Sbjct 234 FDPDKAIQLIETHRVTIVMGVPAIHEAIRQSPLFATTSFDSVRWFYNGGAPCPMELIQHF 293 Query 307 EATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAP 366 + G+ Q YGL+ET T + +D + +AG++G+P +V L + DG Sbjct 294 QERGLPFGQGYGLTETSPTVFMIAKEDA---RRKAGSIGKPVMFCEVRLISDDG---KDV 347 Query 367 GAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSE 426 G G G L +K P M YWN PE TA + DGW+ TGDL E+GF YI GR + Sbjct 348 GQG---EIGELLVKGPNVMKEYWNRPEETANTIRDGWLYTGDLARFDEEGFAYIVGRRKD 404 Query 427 MIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGL-------AVVASAELDE 479 MII GG NI P E++++ + GV+EAA +PDE++G + AV+ A + E Sbjct 405 MIISGGENIYPLELEQVIGELDGVQEAAVVGVPDEKWGEVAKAFIVPKSGAVITEAHIKE 464 Query 480 SAARAL-KHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAAT 530 + L K+ I P + V +T++PR +GK+++ +L T Sbjct 465 HCEQRLAKYKI-------------PKSFVFLTELPRNATGKIVKQALTRLKT 503 >gi|339321983|ref|YP_004680877.1| long-chain-fatty-acid--CoA ligase LcfB [Cupriavidus necator N-1] gi|338168591|gb|AEI79645.1| long-chain-fatty-acid--CoA ligase LcfB [Cupriavidus necator N-1] Length=527 Score = 182 bits (463), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 153/530 (29%), Positives = 240/530 (46%), Gaps = 28/530 (5%) Query 6 FQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSR 65 F + LP V R F AR +PEA+A +G Y E +A L A+ Sbjct 3 FSYLTTLPHAV--RHF--ARLRPEAVAYA-FEGRQTT-YAEFERNTNRVAQALLAEGAGV 56 Query 66 GSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALV-APGSK 124 G R+ I N + +L +K+GA+ A L +E D V A + Sbjct 57 GERIGYIGKNSDHYFELLLGASKIGAVMTPASWRLAPPEVEFILGHCDAVVLFVGAESAA 116 Query 125 MASSAVPEALHSIPVIAVDIAAVTRESEHSL---DAASLAGNADQ-GSEDPLAMIFTSGT 180 M + +P V+ ++ A + + DA A Q + D L ++TSGT Sbjct 117 MVRNLLPALPMVRKVVVMEPCAEQGDWQCYTGWRDAQPDTPPAHQPAAHDVLLQLYTSGT 176 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TG PK +L +R ++ ++E + W WV + + +P HIGG W L L+ G Sbjct 177 TGRPKGAMLTHRNLTIGTEVSERENVRWSHWVADDVSLVAMPVAHIGGSGWGLRNLLSGA 236 Query 241 LCVTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAI 299 V E + ++L+ + ++ LVP + ++ + ++ L+ + YG + Sbjct 237 KGVVAREFDPRAVLDFIEKERISKLFLVPAAMQIVLRDPRARQVDYSRLKYLLYGAAPIP 296 Query 300 AADVRF-IEATGVRTAQVYGLSETGCTALCLPTDDGSIVKI-EAGAVGRPYPGVDVYLAA 357 AA +R IE G Q YG++ET T + LP +D + ++ A G+P PGV++ + Sbjct 297 AALLREGIEVFGCGFVQQYGMTETTGTIVALPPEDHTTEEVPRMRAAGKPLPGVEIKVVD 356 Query 358 TDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERREDG 416 +G APG G L ++S NM GYW PE TA + +GW+ TGD DG Sbjct 357 YEG-RQLAPG-----EVGELVVRSQHNMAGYWKQPEETARTIDAEGWLRTGDAGYMDADG 410 Query 417 FFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFG-ALVGLAVVASA 475 + YI R +MII GG N+ P EV+ G V + A +PDE++G A+ + V+ Sbjct 411 YLYIHDRVKDMIISGGENVYPAEVESAIYGHPQVADVAVIGVPDEKWGEAVKAIVVLKPG 470 Query 476 ELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 + + A I A R+ P +I V +PR SGK++R L Sbjct 471 QAPDQAG------IIAWTRQRLAGFKVPKSIEFVEALPRNPSGKLLRRKL 514 >gi|116694665|ref|YP_728876.1| long-chain-fatty-acid--CoA ligase [Ralstonia eutropha H16] gi|113529164|emb|CAJ95511.1| 4-Coumarate-CoA ligase [Ralstonia eutropha H16] Length=527 Score = 179 bits (455), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 153/530 (29%), Positives = 240/530 (46%), Gaps = 28/530 (5%) Query 6 FQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSR 65 F + LP V R F AR +PEA+A +G Y +A L A+ Sbjct 3 FSYLTTLPHAV--RHF--ARLRPEAVAYA-FEGRQTT-YAGFERNTNRVAQALLAEGAGV 56 Query 66 GSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALV-APGSK 124 G R+ I N + +L +K+GA+ A L +E D V A + Sbjct 57 GERIGYIGKNSDHYFELLLGASKIGAVMTPASWRLAPPEVEFILGHCDAVVLFVGAESAA 116 Query 125 MASSAVPEALHSIPVIAVDIAAVTRESE---HSLDAASLAGNADQ-GSEDPLAMIFTSGT 180 M + +P V+ ++ A E + DA A Q + D L ++TSGT Sbjct 117 MVRNLLPALPMVRKVVVMEPCAGQGEWQCYTDWRDAQPDTPPAHQPAAHDVLLQLYTSGT 176 Query 181 TGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGG 240 TG PK +L +R ++ ++E L W WV + + +P HIGG W L L+ G Sbjct 177 TGRPKGAMLTHRNLTIGTEVSERENLLWSHWVADDVSLVAMPVAHIGGSGWGLRNLLSGA 236 Query 241 LCVTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAI 299 V E + ++L+ + ++ LVP + ++ + ++ L+ + YG + Sbjct 237 KGVVAREFDPRAVLDFIEKERISKLFLVPAAMQIVLRDPRARQVDYSRLKYLLYGAAPIP 296 Query 300 AADVRF-IEATGVRTAQVYGLSETGCTALCLPTDDGSIVKI-EAGAVGRPYPGVDVYLAA 357 AA +R IE G Q YG++ET T + LP +D + ++ A G+P PGV++ + Sbjct 297 AALLREGIEVFGCGFVQQYGMTETTGTIVALPPEDHTTEEVPRMRAAGKPLPGVEIKVVD 356 Query 358 TDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERREDG 416 +G APG G L ++S NM GYW PE TA + +GW+ TGD +G Sbjct 357 YEG-RQLAPG-----EVGELVVRSQHNMAGYWKQPEETARTIDAEGWLRTGDAGYLDAEG 410 Query 417 FFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFG-ALVGLAVVASA 475 + YI R +MII GG N+ P EV+ G V + A +PDE++G A+ + V+ Sbjct 411 YLYIHDRVKDMIISGGENVYPAEVESAIYGHPQVADVAVVGVPDEKWGEAVKAIVVLKPG 470 Query 476 ELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 ++ + A I A R+ P +I V +PR SGK++R L Sbjct 471 QVPDQAG------IIAWTRQRLAGFKVPKSIEFVEALPRNPSGKLLRRKL 514 >gi|262194900|ref|YP_003266109.1| AMP-dependent synthetase and ligase [Haliangium ochraceum DSM 14365] gi|262078247|gb|ACY14216.1| AMP-dependent synthetase and ligase [Haliangium ochraceum DSM 14365] Length=518 Score = 177 bits (450), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 163/546 (30%), Positives = 243/546 (45%), Gaps = 52/546 (9%) Query 14 STVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVIS 73 +T+ + + QPE A G A+ Y EL A +A LR V G RV ++ Sbjct 2 NTLAELIRTHGANQPEVTAFHF--GDQAISYGELDARSNRVANALREAGVGAGDRVAILD 59 Query 74 DNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS--AVP 131 NG E + + A AKLGA+ V N +A E + D A ++ G++ A + A+ Sbjct 60 KNGVEYFELLFATAKLGAVTVAI--NWRLAPREIAYIVDDSQARVMVFGAEYADTMTAIS 117 Query 132 EALHSIPVIAV--------DIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGE 183 +++ + V D A R++ D + AD + +++SGTTG Sbjct 118 DSMSRVAKWVVIGDDDRFSDFGA-WRDASSDSDPQVVTSGADIAFQ-----VYSSGTTGM 171 Query 184 PKAVLLANRTFFAV-PDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLC 242 PK VLLAN F++ P Q G++ +P HIGG W L L HG Sbjct 172 PKGVLLANENLFSLLPTSSQIWGID-----ASSINMVAMPLFHIGGCGWALVGLFHGCTS 226 Query 243 VTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGS----R 297 V E + L+E++ V +VP LL + +A+ SLRL+ YG S + Sbjct 227 VLVREVDPAQLIELIGKYRVTHAFVVPALLQFMQRMPNAASGNYESLRLMIYGASPISEQ 286 Query 298 AIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIV---KIEAGAVGRPYPGVDVY 354 +A VR + G AQ YGL+ET + LP +D + + A G+P+ V++ Sbjct 287 VLAGAVRLM---GCGFAQAYGLTETTGAIVTLPPEDHDLNGPNRHRLRAAGKPHDNVELR 343 Query 355 LAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNN-PERTAEVLIDGWVNTGDLLERR 413 + D G P P G +W +S N++GYW + V DGW+ TGD+ Sbjct 344 IVDPD-TGEDLPLGTP----GEIWTRSGQNLVGYWQEGRQEPPPVNEDGWLRTGDIGYFD 398 Query 414 EDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA 473 DG+ YI R +MII GG N+ P EV+ V + A IP E++G VV Sbjct 399 ADGYIYIHDRLKDMIITGGENVYPAEVENALMNHPAVADVAVIGIPSEKWGESPFAIVVP 458 Query 474 SAE--LDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATA 531 ++E DE+ A F+ P I +IPR SGKV++ L A A Sbjct 459 TSESAADEAEILGFARDNLAHFK-------VPVGIDFRAEIPRNASGKVLKKDLRAPYWA 511 Query 532 DKARVV 537 ++R V Sbjct 512 GQSRAV 517 >gi|73537400|ref|YP_297767.1| long-chain-fatty-acid--CoA ligase [Ralstonia eutropha JMP134] gi|72120737|gb|AAZ62923.1| AMP-dependent synthetase and ligase [Ralstonia eutropha JMP134] Length=526 Score = 177 bits (448), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 152/532 (29%), Positives = 239/532 (45%), Gaps = 33/532 (6%) Query 6 FQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSR 65 F + LP V R F R P+A+A +G Y E +A L A V Sbjct 3 FSYLATLPHAV--RHFAGLR--PDAVAYA-FEGRQT-SYAEFERNTSRVAQALLAAGVRA 56 Query 66 GSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKM 125 G R+ I N + + L AK+GA+ A L +E D V P S Sbjct 57 GDRIGYIGKNCDHYFEAWLGAAKMGAVMTPASWRLAGPEVEFIIGHCDAVMLFVGPES-- 114 Query 126 ASSAVPEALHSIPVIAVDIAAVTRESE--------HSLDAASLAGNADQGSEDPLAMIFT 177 ++ V L ++P++ IA S+ A+L + + D + ++T Sbjct 115 -TAMVQGLLPALPMVRQVIAMEAGGSQDWPVYTDWRDAHPATLP-DHQPDAHDVVLQLYT 172 Query 178 SGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLM 237 SGTTG PK +L +R ++ ++E + W W + + +P HIGG W L L+ Sbjct 173 SGTTGRPKGAMLTHRNLTIGTEVSERESIPWSHWTADDISLVAMPVAHIGGSGWGLRNLL 232 Query 238 HGGLCVTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGS 296 G V E + ++L+ + ++ +VP + ++ + ++ + L+ + YG + Sbjct 233 SGAKGVVAREFDPRAVLDFIEYERISKLFMVPAAMQIVLRDPRARSVDYSRLKYLLYGAA 292 Query 297 RAIAADVRF-IEATGVRTAQVYGLSETGCTALCLPTDDGSIVKI-EAGAVGRPYPGVDVY 354 AA +R IE G Q YG++ET T + LP +D + ++ A G+P PGV++ Sbjct 293 PIPAALLREGIEVFGCGFVQQYGMTETTGTVVALPPEDHTTEEVPRMRAAGKPLPGVELK 352 Query 355 LAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERR 413 + +G APG G + ++S NM GYW PE TA + DGW+ TGD Sbjct 353 VVDYEG-RELAPG-----EVGEVVVRSAHNMSGYWKQPEETARTIDADGWLRTGDAGYLD 406 Query 414 EDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA 473 +G+ YI R +MII GG N+ P EV+ G V + A +PDE++G V VV Sbjct 407 AEGYLYIHDRVKDMIISGGENVYPAEVESAIYGHPIVADVAVIGVPDEKWGEAVKAIVVL 466 Query 474 SAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 A A + +I A R+ P +I V +PR SGK++R L Sbjct 467 KA-----GQAADRESIVAWTRQRLAGFKVPKSIDFVDALPRNPSGKLLRRKL 513 >gi|192289242|ref|YP_001989847.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris TIE-1] gi|192282991|gb|ACE99371.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris TIE-1] Length=508 Score = 176 bits (447), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 155/533 (30%), Positives = 243/533 (46%), Gaps = 45/533 (8%) Query 17 LDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNG 76 D + A +PE IA+ + + YR + V LAA L A V RG RV V++ N Sbjct 6 FDWIAHHAEVRPERIAVVDLATSRKISYRAMDERVDRLAAHLAALGVGRGDRVAVLALNA 65 Query 77 PETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVP-EALH 135 ET AC +LGAI V + L + + + D A ++A ++A A +A Sbjct 66 VETLEVQFACFRLGAIFVPLNVRLTVHELSYI--VGDAAPRVLAHDDELAPMATELKAAC 123 Query 136 SIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMI-FTSGTTGEPKAVLLANRTF 194 S+P + A E +L A+ L G ++ + D ++ I +TSGTTG+PK ++ + Sbjct 124 SVP----HLLAFGPAYEAALAASPLLGASEPVTLDDVSTIMYTSGTTGKPKGAMITHGMT 179 Query 195 FAVPDILQKEGLNWVTWVVGETTY-SPLPATHIGGLWWILTCLMHGG--LCVTGGENTTS 251 F + L ++ T + LP H GGL ++H G + + + Sbjct 180 F-----INAVNLGIPAFISQRTVFLCVLPLFHTGGLNCYTNPVLHAGGTTLLMRAFDPGA 234 Query 252 LLEILTTNAVATTCL--VPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEAT 309 L I+ +V T VP++ + A + L++ G GG+ ++ + Sbjct 235 ALSIIGDPSVGLTHFFGVPSIYQFMCQHAAFAATDLLRLQIAGVGGAPMPVPLLKIWQER 294 Query 310 GVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAG 369 G Q YG++ET L L DD + +AG+ G+P D+ + DG P PG Sbjct 295 GCALVQGYGMTETSPAVLMLDADDAAR---KAGSAGKPVLHADLKIVGPDG-APVKPG-- 348 Query 370 PSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMII 429 G LW+K P GYWN P+ DGW++TGD ++GF+YI R+ +M I Sbjct 349 ---EMGELWVKGPNITPGYWNRPDANRTSFTDGWLHTGDAARVDDEGFYYIVDRTKDMYI 405 Query 430 CGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA---SAELDESAARALK 486 GG N+ P EV+ + + + EAA PD ++G G+AVVA EL E+ A Sbjct 406 SGGENVYPAEVEDVLYQLPEIAEAAVIGAPDPQWGE-TGVAVVALKPGQELSEAKLLAHC 464 Query 487 HTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVR 539 ARF+ P + V +PR +GKV + +L + R++VR Sbjct 465 RERLARFK-------CPQRVSFVEALPRNATGKVHKPTL-------RERILVR 503 >gi|149185931|ref|ZP_01864246.1| acyl-CoA synthase [Erythrobacter sp. SD-21] gi|148830492|gb|EDL48928.1| acyl-CoA synthase [Erythrobacter sp. SD-21] Length=516 Score = 176 bits (446), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 152/540 (29%), Positives = 242/540 (45%), Gaps = 36/540 (6%) Query 9 MPQLPSTVLDRVFEQ-ARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGS 67 M + P D+ AR++P AL + DG +A+ + E + A L A+ +++G Sbjct 1 MSEEPKLSFDQFIRHWARERPGHTALEQ-DG-AAITFGEFEERSRKIVAMLAARGIAKGD 58 Query 68 RVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMAS 127 RV + N + + A++GA+ V L AA E + D A L++ G Sbjct 59 RVAWLGKNSRLYFELFYSAARMGAVMVPIGWRL--AAPEVAYILGDTGAKLLSIGEGFEE 116 Query 128 SAVPE--ALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPK 185 +A + S P + T ++E +++ + G +D + ++TSGTTG PK Sbjct 117 AAAKACGQMDSPPQVIS-----TPDAEGAIENEAAKEFEPAGPDDAVLQLYTSGTTGNPK 171 Query 186 AVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTG 245 +L NR FA+ ++EG W + E +P HIGG + + G + Sbjct 172 GAVLTNRNLFALRVPSEEEGQPWSHFDEDEAILVCMPCAHIGGTGLGIMAMSSGIRAIVQ 231 Query 246 GENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAAD--- 302 E T + + +VP L +V ++ + +++ V YG + I D Sbjct 232 EEFTPDGVLDGFEQGITRLFIVPAALQMVVQHPRAKTTDMSAIKYVLYGAA-PIPLDLLR 290 Query 303 --VRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIV-KIEAGAVGRPYPGVDVYLAATD 359 V+ I G Q YG++ET T LP +D + + G+ PGV++ + D Sbjct 291 EAVKTIPDAGF--LQCYGMTETTGTIAALPPEDHDLDGNQRMKSAGKAVPGVELKVIGED 348 Query 360 GIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFY 419 P G L +SP+NM GYWN PE T L+DGW++TGD EDG+ Y Sbjct 349 D------AELPRGEVGELICRSPSNMAGYWNLPEATESSLVDGWMHTGDAAYMDEDGYVY 402 Query 420 IKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVAS--AEL 477 I+ R +MII GG N+ P +V+ G + E A +PDE +G V +V EL Sbjct 403 IQDRMKDMIISGGENVYPAQVESAIYGHPQIAEVAVIGVPDETWGETVKACIVLKPGEEL 462 Query 478 DESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 DE++ A A F+ P +I ++ +PR SGK++R L A + R V Sbjct 463 DEASVIAWTKERLAGFK-------VPRSIDVLDVMPRNASGKILRKDLRAPYWKGRERQV 515 >gi|197105973|ref|YP_002131350.1| long-chain-fatty-acid--CoA ligase [Phenylobacterium zucineum HLK1] gi|196479393|gb|ACG78921.1| long-chain-fatty-acid--CoA ligase [Phenylobacterium zucineum HLK1] Length=533 Score = 176 bits (446), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 157/534 (30%), Positives = 232/534 (44%), Gaps = 27/534 (5%) Query 14 STVLDRVFEQARQQPEAIALR-RCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVI 72 +T+ D QAR +P+A+AL T+ ++ L V A L A + +G R+ + Sbjct 16 TTLGDVARYQARVRPDAVALEFEGRATTFGQFDRLTNRV---ANALAAAGLRKGQRIAYV 72 Query 73 SDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPE 132 N + ++ AK G + L + Q ++ V P ++ V Sbjct 73 GKNSDHYFELLVGAAKAGVVMTPIGWRLAPPEVAYIVQDSEAPIVFVGPEVMGHTAEVAA 132 Query 133 ALHSIP-VIAVDIAAVTRESEHSLDAASLAGNA-DQGSEDPLAMIFTSGTTGEPKAVLLA 190 L P VIA++ R E DAA A D ++TSGTTG PK V+L Sbjct 133 LLERRPQVIAMEPGGGERLYETWRDAAPDTDPAVPVTPHDVAVQLYTSGTTGRPKGVMLT 192 Query 191 NRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGE-NT 249 + + ++W TW + + +P HIGG W L LM+G V E + Sbjct 193 HENILGGRRTAAEAKMDWNTWGPDDISLVAMPVAHIGGTGWGLVGLMNGAKGVVAREFDP 252 Query 250 TSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV--RFIE 307 +L+ + + V+ +VP L +V + ++ + L+ + YG S I D+ +E Sbjct 253 MKVLDFIEHDRVSKMFMVPAALQIVVRQPRARSVDFSRLKYILYGAS-PIPLDLLRECME 311 Query 308 ATGVRTAQVYGLSETGCTALCLPTDDGSIV-KIEAGAVGRPYPGVDVYLAATDGIGPTAP 366 G Q YG++ET T + LP +D A G P PGV++ + D G T P Sbjct 312 VFGCGFVQQYGMTETCGTIVYLPPEDHDPAGNPRMRAAGVPMPGVEIKV--IDAEGRTLP 369 Query 367 GAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERREDGFFYIKGRSS 425 G + +S ANM GYW E TA + DGW+ TGD EDG+ YI R Sbjct 370 ----LGQVGEVATRSVANMAGYWKQREATANTIDADGWLRTGDAGYLDEDGYLYIHDRVK 425 Query 426 EMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVAS--AELDESAAR 483 +MII G NI P EV+ G V E A +PDE++G V VV +D Sbjct 426 DMIISGAENIYPAEVESAIYGHPAVSEVAVIGVPDEKWGEAVKAVVVPKPGMTIDPQEII 485 Query 484 ALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 A T A F+ P ++ +V IPR SGK++R L A + R V Sbjct 486 AFARTRIAGFK-------VPKSVEVVEAIPRNASGKILRRELREPYWAGRERRV 532 >gi|85375345|ref|YP_459407.1| long-chain-fatty-acid--CoA ligase [Erythrobacter litoralis HTCC2594] gi|84788428|gb|ABC64610.1| long-chain-fatty-acid--CoA ligase, putative [Erythrobacter litoralis HTCC2594] Length=512 Score = 176 bits (445), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 157/527 (30%), Positives = 240/527 (46%), Gaps = 34/527 (6%) Query 9 MPQL--PSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRG 66 MP P T+ + QA ++P +ALR D ++ Y E +A L A +G Sbjct 1 MPDFSGPVTLGHALAAQAEERPADVALRFGDRVTS--YAEYDRHATQIANGLAALGFEKG 58 Query 67 SRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMA 126 R+ + N L + G + V L A IE IT A A V Sbjct 59 DRIAYLGKNSDHAVELFLGTVRGGFVFVPVIWRLAPAEIEF---ITRDAGATVL------ 109 Query 127 SSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLA-GNADQGSEDPLAMIFTSGTTGEPK 185 V E S+P I + RE + DA S + D D + ++TSGTTG PK Sbjct 110 --FVEEGFESVPFEGRKIV-MEREFANWRDAQSEDLVDTDVAVGDAMLQLYTSGTTGLPK 166 Query 186 AVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTG 245 V+L++ ++ IL+ GL+W + G + +P HI G+ ++ G + Sbjct 167 GVVLSHANATSMRPILRASGLDWASADPGTSIILAMPYGHIAGVGLAGGAVLAGQQLIIH 226 Query 246 GE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV- 303 E + + + + + V LVP + ++S +A A S++ + YG S I D+ Sbjct 227 AEFDPAATIRDIRDHRVEYIFLVPAAIRIVLSHPDAATADFSSIKGLNYGAS-PIPLDLL 285 Query 304 -RFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEA-GAVGRPYPGVDVYLAATDGI 361 +E AQ+YG++ET T + LP +D + + + G+ PG ++ + + + Sbjct 286 KEGVERLKCDFAQMYGMTETYGTVVSLPPEDHKPGREKVMRSAGKALPGNEIRIL-DENL 344 Query 362 GPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLI-DGWVNTGDLLERREDGFFYI 420 P PG G + IKSP+NM+GYWN PE TA+ LI DGW+ TGD EDG+ YI Sbjct 345 QPLPPG-----EIGEVAIKSPSNMIGYWNRPEETAKTLIGDGWLRTGDAGILDEDGYLYI 399 Query 421 KGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDES 480 + R +MII GG N+ P EV+ G V + A +PDE++G V VVA + Sbjct 400 QDRIKDMIISGGENVYPAEVESALFGHDDVADVAVIGVPDEKWGEAVKAIVVARPGCEPD 459 Query 481 AARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAA 527 A + H R P ++ V +PR SGK++R L A Sbjct 460 ADAIIAHA-----RERIAAFKCPKSVEFVEALPRNPSGKILRRELRA 501 >gi|149919197|ref|ZP_01907680.1| putative long-chain-fatty-acid--CoA ligase [Plesiocystis pacifica SIR-1] gi|149819911|gb|EDM79333.1| putative long-chain-fatty-acid--CoA ligase [Plesiocystis pacifica SIR-1] Length=530 Score = 174 bits (441), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 171/536 (32%), Positives = 245/536 (46%), Gaps = 47/536 (8%) Query 18 DRVFEQARQQPEAIALRRCD--GTS-----ALRYRELVAEVGGLAADLRAQSVSRGSRVL 70 D + +AR P A A+ GTS AL Y L AE +A LR Q V RG RV Sbjct 9 DWLARRARLSPSAPAILDVSAPGTSPAEPRALSYAALEAETNQVARWLRVQGVERGDRVA 68 Query 71 VISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAA-ALVAPGSKMASSA 129 +++ N E + ACAKLGA+ + L A + +PA +++ + Sbjct 69 ILAKNRLEYLELLFACAKLGAVLQALNWRLTPAELGPLIAAAEPALLCWDQTFAELVDAL 128 Query 130 VPEALHSIPVIAVDIAAVTRE----SEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPK 185 P + +A+D A+ E S +L + L A G + P + +T GTTG PK Sbjct 129 RPSLPSGLRTVALDDASTQTELRLASCRALGSEPLEREA-FGPDQPWVLCYTGGTTGLPK 187 Query 186 AVLL--ANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLC- 242 A +L A T+ AV + + GL+ G+ P H GGL T L+H G C Sbjct 188 AAVLTHATVTWNAV-NTVASWGLD-----AGDLAVLNAPMFHTGGLNVFTTPLIHAGGCS 241 Query 243 -VTGGENTTSLLEILT------TNAVATTCL--VPTLLSKLVSELKSANATVPSLRLVGY 293 + + L +L T +C VP + + ++ + A A + L+L+ Sbjct 242 VLCRAFDLDELYALLAAPLPTPTGPRGVSCFFGVPAMFQAMQADPRWAEAPLERLKLIIS 301 Query 294 GGSRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDV 353 GG+ A A G+ YGL+E G LP + V+ + GAVG P VDV Sbjct 302 GGAPCPAPVFEGFWARGIDFKTGYGLTEAGPNNFWLPPER---VREKPGAVGWPLMHVDV 358 Query 354 YLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERR 413 +A D G P G G LWI+ P GY+ NPE TA +DGW+ TGDL Sbjct 359 RVA--DETGEPCPADG----VGELWIRGPHVSPGYYANPEATAASFVDGWLRTGDLAVAD 412 Query 414 EDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA 473 +G I GRS +MII GG NI P +++ V EAA +PDE +G VG A V Sbjct 413 AEGCVTIVGRSKDMIISGGENIYPAQIESAMSSHPAVAEAALIGVPDERWGE-VGRAFVV 471 Query 474 SAELDESAARALKHTIAARFRRESEPMAR---PSTIVIVTDIPRTQSGKVMRASLA 526 A DE +A + F E +AR P ++V++ +PRT +GK+ + +LA Sbjct 472 LAA-DEPSAEGFSAEVLLAFLGER--LARYKLPKSVVVLDALPRTGAGKIDKRALA 524 >gi|103487349|ref|YP_616910.1| acyl-CoA synthetase [Sphingopyxis alaskensis RB2256] gi|98977426|gb|ABF53577.1| AMP-dependent synthetase and ligase [Sphingopyxis alaskensis RB2256] Length=519 Score = 174 bits (440), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 149/520 (29%), Positives = 232/520 (45%), Gaps = 26/520 (5%) Query 24 ARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSV 83 A ++P+ +ALR D + +L +A+ L +++G RV I N ++ Sbjct 19 AAERPDRVALREED--RVYSHGDLDDLTARVASALLGAGLNKGDRVAWIGKNSDLYFILF 76 Query 84 LACAKLGAIAVMADGNLPIAAIERFCQITDPAAALV--APGSKMASSAVPEALHSIPVIA 141 A+ G VMA ++ E + D A +V PG + + + L PVI Sbjct 77 YGAARAGI--VMAPVGWRLSPAEWAFIVNDTRAKMVFAGPGFEGLADQLAGRLEHDPVI- 133 Query 142 VDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDIL 201 VD A ++ ++ A+ G+ D + ++TSGTTG PK +L+NR FA+ Sbjct 134 VDAA----KAWAMIEGAARTAFDPSGANDAVLQLYTSGTTGNPKGAVLSNRNLFALRKHS 189 Query 202 QKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGE-NTTSLLEILTTNA 260 L + W E +P HIGG + L G + E N + + + + Sbjct 190 STLDLPYTRWDDDEAVLVAMPCAHIGGTGLGIMALAAGLPGIVLAEFNPEGVFDAVEQHG 249 Query 261 VATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVR-FIEATGVRTAQVYGL 319 V +VP L L+ + + L+ + YG + +R I+ G + Q YG+ Sbjct 250 VTRFFMVPAALQMLLMHPRCTSVDYSRLKYILYGAAPIPLELLRQCIQVFGAQFIQAYGM 309 Query 320 SET-GCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLW 378 +ET G ++ P D + G+ PGV++ + DG P P+ G + Sbjct 310 TETTGTISMLPPEDHDPAGNKRMRSAGKALPGVEIRVVDADG-NPL-----PTGEVGEVV 363 Query 379 IKSPANMLGYWNNPERTAEVLID-GWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAP 437 +S NMLGYWN P+ TA + D GW+ TGD EDG+ +I R +MII GG N+ P Sbjct 364 TRSSNNMLGYWNLPDATANTMTDDGWIRTGDAGYLDEDGYLFIHDRMKDMIITGGENVYP 423 Query 438 DEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRES 497 EV+ G V+E A IPD ++G V VVA + AR + I A R Sbjct 424 AEVESAIFGHPAVQEVAVIGIPDAKWGESVKAVVVA-----KPGARIEEADIIAWARERI 478 Query 498 EPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 P P +I ++ +PR SGK++R L A R+V Sbjct 479 APFKCPRSIDVIDALPRNASGKILRKDLRAPYWEGYERMV 518 >gi|51891936|ref|YP_074627.1| putative long-chain fatty-acid-CoA ligase [Symbiobacterium thermophilum IAM 14863] gi|51855625|dbj|BAD39783.1| putative long-chain fatty-acid-CoA ligase [Symbiobacterium thermophilum IAM 14863] Length=501 Score = 174 bits (440), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 142/502 (29%), Positives = 216/502 (44%), Gaps = 41/502 (8%) Query 28 PEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACA 87 P+A LR L Y + +A L Q V RG RV V+S N E + AC Sbjct 36 PQAEPLR-------LTYDQWNRMANRMAHFLLEQGVRRGDRVAVLSQNCLEMLTLLFACG 88 Query 88 KLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAVDIAAV 147 KLGAI V + L +A + TDP P + A + + + + ++ +D++ Sbjct 89 KLGAIYVPYNWRLTVAELRPLVADTDPRIFFYGPHFEQAVAEL-QPPKPVGLLNLDLSGY 147 Query 148 TRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLN 207 E+ + D EDP +++T GTTG K +L++R +L Sbjct 148 PEETPPA---------PDLDPEDPWMILYTGGTTGRSKGAVLSHRA------VLWNAWNT 192 Query 208 WVTWVVGETTYSPL--PATHIGGLWWILTCLMHGGLC--VTGGENTTSLLEILTTNAVAT 263 W + P+ P H GGL T L+ G C + G + LL+ + + Sbjct 193 IAGWTLSPDDRVPILTPFFHTGGLNVFTTPLVELGGCSILMGPFDPGELLDAVEKERLTV 252 Query 264 TCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQVYGLSETG 323 +VPT+ ++ + A +R + GG+ A G + YGL+E G Sbjct 253 IFMVPTMFKMVMDHPRFAETDFSRVRFLISGGAACPEPVQLAYRAKGCQFKIGYGLTEAG 312 Query 324 CTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPA 383 +P D S K G+VG P P + + + A DG + G L IK Sbjct 313 PNTFGMP-DHRSWDK--PGSVGFPLPHIQLRIVAEDG------RLCGTNEVGELLIKGGH 363 Query 384 NMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRI 443 GYW NPE TAE L DGW++TGDL R E+GF+YI GR EM I GG N+ P EV+ Sbjct 364 VFSGYWRNPEATAEALQDGWLHTGDLARRDEEGFYYIVGRKKEMFISGGENVFPLEVEDA 423 Query 444 AEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARP 503 V E A IPD ++G + VV + + ++H R+ P Sbjct 424 IYQHPAVAECAVVGIPDPKWGEVGKAFVVLKPGMRLTEEELIEHC-----RKLLAKYKIP 478 Query 504 STIVIVTDIPRTQSGKVMRASL 525 + + ++P+ +GK+++ L Sbjct 479 KQVEFLPELPKNAAGKILKREL 500 >gi|94313871|ref|YP_587080.1| acyl-CoA synthetase [Cupriavidus metallidurans CH34] gi|93357723|gb|ABF11811.1| acyl-CoA synthetase [Cupriavidus metallidurans CH34] Length=521 Score = 173 bits (439), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 155/538 (29%), Positives = 235/538 (44%), Gaps = 67/538 (12%) Query 15 TVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISD 74 T+ + + + P+ +A DG + + YR L + + RA + RG V+ +S Sbjct 11 TIGEMIVHAIDRYPDRVAF--IDGDARMTYRALGDRISQAISAFRALGLVRGDCVVQLSG 68 Query 75 NGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEAL 134 N PE ++ + A +G +V + ++ I D A A V MA E Sbjct 69 NRPEVFIVMAAAYLMGLRSVTLHA---MGGVDDHAYIVDDAEARVF----MADPVYAERA 121 Query 135 HSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSE-------------DPLAMIFTSGTT 181 ++ A V H+ D L DQ + D + + +T GTT Sbjct 122 LAL---RERCAGVAHWFGHA-DVPGLPSFWDQATSFAPARLVPEALTTDVIRLAYTGGTT 177 Query 182 GEPKAVLLANRTFF----------AVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWW 231 G+PK V+LANR + ++PD L+ P P +H G Sbjct 178 GKPKGVMLANRCVWMQAVLLLAARSLPDDLR--------------LLCPTPISHGAGAMI 223 Query 232 ILTCLMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLV 291 + T G + + G + ++ + T+ + T LVPT++ L+ ++ A SL+ + Sbjct 224 VPTLWRGGTIILQHGFDAERFIDAVETHRASMTFLVPTMIYTLLDHPRARTADFSSLQTL 283 Query 292 GYGGSRAIAADVR-FIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAG-AVGRPYP 349 YG S A +R I+ G AQ YG +E L L +D ++ + G PYP Sbjct 284 SYGASPMAPARIREAIDRFGPILAQSYGQTECPSNILQLTQEDHMRTDVDTSTSAGMPYP 343 Query 350 GVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDL 409 GV V L D P APG S G L ++SP M GYW P+ TA L +GW++TGD+ Sbjct 344 GVTVALL-DDNDEPVAPG-----SVGELCVRSPLVMDGYWKQPQLTALALRNGWLHTGDM 397 Query 410 LERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGL 469 R + G++Y+ R +MII GG N+ P EV+ + G GV AA +PD ++G V Sbjct 398 AYRDQFGYYYLVDRKKDMIISGGFNVYPKEVEDVLTGHPGVAAAAVIGVPDAKWGEAVKA 457 Query 470 AVV--ASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 VV A+LD A RAL R + P TI V +P T GK + L Sbjct 458 VVVPRPGAQLDVEALRAL-------VRHAKGAVNTPKTIDFVDALPLTALGKPDKKQL 508 >gi|159036889|ref|YP_001536142.1| AMP-dependent synthetase and ligase [Salinispora arenicola CNS-205] gi|157915724|gb|ABV97151.1| AMP-dependent synthetase and ligase [Salinispora arenicola CNS-205] Length=5154 Score = 171 bits (434), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 153/515 (30%), Positives = 221/515 (43%), Gaps = 47/515 (9%) Query 22 EQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYL 81 E A + P +A D A+ Y +L A LA LR V RG RV + T Sbjct 15 ENAARFPGKVAFE--DDRRAVTYADLEARTRRLAGHLRGLGVKRGDRVAIWLRQSVSTVE 72 Query 82 SVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIA 141 S LA + G + V + + A +E ++D A V + A P H V+ Sbjct 73 SYLAVVRAGGVGVPLNPDAAQAELEYL--LSDSGATAVITDAVQAQRLRPTP-HRALVVT 129 Query 142 VDI-AAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRT------- 193 D+ A E ++ D G +D M +TSGTTG PK VL R Sbjct 130 GDVPAGALSYDELAVSEPEQPAGDDLGLDDVAWMFYTSGTTGRPKGVLSTQRNCLWSVAS 189 Query 194 -FFAVPDILQKEGLNWVTWVVGETTYSPLPATH-IGGLWWILTCLMHGGLC-VTGGENTT 250 + +P + ++ + W PLP H + + +L+ + G + G + Sbjct 190 CYVPIPGLTDQDRVLW-----------PLPLFHSLSHIACVLSVTVVGATARIMDGSSVQ 238 Query 251 SLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVR--FIEA 308 ++ L VPT +LVS + T PSLR +G G + A++R F E Sbjct 239 DVMRALQQEEPTFLAGVPTTYQQLVSAARRHGFTAPSLR-IGLAGGAVLGAELRQEFEET 297 Query 309 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGA 368 GV YG +ET C A+ + DG + G+ G P PGV V + + PT G Sbjct 298 FGVPLVDAYGSTET-CGAITINPPDGPRIN---GSCGLPVPGVGVRI-----VDPTTGGD 348 Query 369 GPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMI 428 P+ + G +W+ P M+GY N+PE TA+ + DGW TGDL R G+ I GR E++ Sbjct 349 LPAGAEGEVWVSGPNVMVGYHNSPEATAKAMRDGWFRTGDLARRDGAGYLTISGRIKELV 408 Query 429 ICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGAL-VGLAVVASAELDESAARALKH 487 I GG NI P EV+ + V GV + A +P E G + V + D Sbjct 409 IRGGENIHPVEVEAVLRTVPGVADVAVAGVPHETLGEVPVAYVIPGPDGFD-------VE 461 Query 488 TIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMR 522 ++ R R + P + V IPRT SGKV R Sbjct 462 SLVTRCREQLSAYKVPHQVHEVASIPRTASGKVQR 496 >gi|341820478|emb|CCC56759.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Weissella thailandensis fsh4-2] Length=483 Score = 171 bits (434), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 138/512 (27%), Positives = 240/512 (47%), Gaps = 54/512 (10%) Query 22 EQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYL 81 ++A+ P+ +A++ + + L + ++ +V +A L AQ R+ VI+ N + YL Sbjct 7 KRAQLSPDRLAVQYQE--TKLTFAQMKEKVQRIATQL-AQLAQNEERIAVITSNQLQGYL 63 Query 82 SVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS-AVPEALHSIPVI 140 +LA +LG V+ N ++A E Q+ D +V A + +V + + V+ Sbjct 64 MILAVQQLGKTVVLI--NRRLSAREINFQLQDAGVQVVVQDDDFALTLSVDQQVSFTEVL 121 Query 141 AVDIAAVTRE-SEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVL--LANRTFFAV 197 A+ + + +E LDA + ++++TSGTTG PK V+ N + AV Sbjct 122 AIPVTTLIEPVAEFDLDAVT-------------SIMYTSGTTGNPKGVMQTFGNHFYSAV 168 Query 198 PDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHG-GLCVTGGENTTSLLEIL 256 L + W+ + +P HI GL ++ L++G G+ + + ++ L Sbjct 169 GSALNLGIMADDVWL------AVVPIFHISGLSIMMRSLIYGMGVRLFEKFDVHAINHAL 222 Query 257 TTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQV 316 V T +VP +L++L++EL + + R + GG ++ +A G+ Q Sbjct 223 LNGEVTTISVVPMMLTQLLAELPANTRYHKNFRTMLLGGGPTDLTTLQRAKAAGIEVVQS 282 Query 317 YGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGT 376 YG++ET + L D + + + G+ G+P V + +A D G Sbjct 283 YGMTETASQVIAL---DAANAQRKLGSAGKPLFPVSIRVAHQD-----------DQQHGR 328 Query 377 LWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIA 436 + IKSP +GY N PE+ A DGW +TGD+ ++GF +I GR +MI GG N+ Sbjct 329 IQIKSPTLAVGYLNQPEKYANTFEDGWFDTGDMGWLDDEGFLFIDGREGDMISSGGENVF 388 Query 437 PDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAE---LDESAARALKHTIAARF 493 PDE++ I + +++ A +PD+++GA V +A V + L A R + A + Sbjct 389 PDEIESIYAKLDEIKQIAVVGVPDKKWGA-VPVAFVTFKDGQTLSRQALRDFGRDMLAHY 447 Query 494 RRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 + P+ TD PRT SGKV R L Sbjct 448 K-------VPAHFYKATDFPRTASGKVQRHKL 472 >gi|145220633|ref|YP_001131311.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] gi|145213119|gb|ABP42523.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] Length=509 Score = 171 bits (432), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 159/530 (30%), Positives = 237/530 (45%), Gaps = 38/530 (7%) Query 18 DRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGP 77 D V R +P+A AL D T + YREL A V G RV + NG Sbjct 7 DIVRSHGRNRPDAPALIVGDRT--VSYRELDERSNRTAQAFSRTGVGPGDRVAFVERNGI 64 Query 78 ETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSI 137 E + AKLGA+AV N + A E I D A++V G + EA+ Sbjct 65 EFFDVAFGSAKLGAVAVPV--NWRLTAPEMRHVIADCGASVVVVGQEFTGRI--EAIADD 120 Query 138 PVIAVDIAAVTRESEHSLDAASLAGNAD----QGSEDPLAMIFTSGTTGEPKAVLLANRT 193 + V + R D + A D G +D + +++TSGTTG PK V+L+N Sbjct 121 LDVEVVVIGKHRHWPTFDDLLAAAPAVDPGVVTGPDDLVFLMYTSGTTGAPKGVMLSNAN 180 Query 194 FFAVPDILQKEGLN--WVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGE-NTT 250 + + G+ W + + + +P H+ G W L L G + V + + Sbjct 181 V-----VCKTAGVGGPW-KFDADSVSLAVMPLFHMAGFGWALAGLWEGAVTVVLRDVDPG 234 Query 251 SLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV--RFIEA 308 ++L+ + + V LVP ++ L+ + + LR+V YG S I DV R I+ Sbjct 235 AILDAVARHRVTNMLLVPAVIQFLLDTTGLDDTDLSRLRIVVYGAS-PITDDVLMRGIDR 293 Query 309 TGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGA 368 G AQVYG++E+ + L D+ + + GRPYP V + + + PT Sbjct 294 FGGIFAQVYGMTESTGSVTQLDGDEHLPQLLRS--CGRPYPWVQIRV-----VDPTGRDV 346 Query 369 GPSASFGTLWIKSPANMLGYWNNPERTAEVLI-DGWVNTGDLLERREDGFFYIKGRSSEM 427 P + G +W +S NMLGYWNNPE TA L DGW+ TGD DG+ Y+ R +M Sbjct 347 AP-GTVGEVWTRSDQNMLGYWNNPEATAATLTPDGWLRTGDAGYLDRDGYLYLHDRIKDM 405 Query 428 IICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKH 487 I+ G N+ P EV+ + V + A IPD +G V VVA A + E+ A Sbjct 406 IVSGAENVYPAEVENVLMTHPAVTDVAVIGIPDTRWGEAVKAVVVAGAPVTEAELIAFAR 465 Query 488 TIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 A F+ P ++ V +PR SGK+++ L D+ R + Sbjct 466 EQLAGFK-------LPKSVDFVDALPRNPSGKLLKRQLREPYWTDEDRHI 508 >gi|39933820|ref|NP_946096.1| putative acid-CoA ligase [Rhodopseudomonas palustris CGA009] gi|39647667|emb|CAE26187.1| putative acid-CoA ligase [Rhodopseudomonas palustris CGA009] Length=508 Score = 171 bits (432), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 150/532 (29%), Positives = 237/532 (45%), Gaps = 43/532 (8%) Query 17 LDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNG 76 D + A +PE IA+ + + YR + V LAA L A V RG RV V++ N Sbjct 6 FDWIAHHAEVRPERIAVVDLASSRKISYRAMDERVDRLAAHLAALGVGRGDRVAVLALNA 65 Query 77 PETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVP-EALH 135 ET AC +LGAI V + L + + + D A ++A ++A A +A Sbjct 66 VETLEVQFACFRLGAIFVPLNVRLTVHELSYI--VGDAAPRVLAHDDELAPMAKELKAAC 123 Query 136 SIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFF 195 S+P + +A + L + +D +++TSGTTG+PK ++ + F Sbjct 124 SVPHL---LAFGAAYEAALAASPRLGASEPVTLDDVSTIMYTSGTTGKPKGAMITHGMTF 180 Query 196 AVPDILQKEGLNWVTWVVGETTY-SPLPATHIGGLWWILTCLMHGG--LCVTGGENTTSL 252 + L ++ T + LP H GGL ++H G + + + Sbjct 181 -----INAVNLGIPAFISQRTVFLCVLPLFHTGGLNCYTNPVLHAGGTTLLMRAFDPGAA 235 Query 253 LEILTTNAVATTCL--VPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATG 310 L I+ +V T VP++ + A + L++ G GG+ ++ + G Sbjct 236 LSIIGDPSVGLTHFFGVPSIYQFMCQHPAFAATDLSRLQIAGVGGAPMPVPLLKIWQERG 295 Query 311 VRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGP 370 Q YG++ET L L DD + +AG+ G+P D+ + DG P PG Sbjct 296 CALVQGYGMTETSPAVLMLDADDAAR---KAGSAGKPVLHADLKIVGPDG-DPVKPG--- 348 Query 371 SASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIIC 430 G LW+K P GYWN P+ DGW++TGD ++GF+YI R+ +M I Sbjct 349 --EMGELWVKGPNITPGYWNRPDANRTSFTDGWLHTGDAARVDDEGFYYIVDRTKDMYIS 406 Query 431 GGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA---SAELDESAARALKH 487 GG N+ P EV+ + + + EAA PD ++G G+AVVA EL E+ A Sbjct 407 GGENVYPAEVEDVLYQLPEIAEAAVIGAPDPQWGE-TGVAVVALKPGQELSEAKLLAHCR 465 Query 488 TIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVR 539 ARF+ P + V +PR +GKV + +L + R++VR Sbjct 466 ERLARFK-------CPQRVSFVEALPRNATGKVHKPTL-------RERILVR 503 >gi|156741756|ref|YP_001431885.1| AMP-dependent synthetase and ligase [Roseiflexus castenholzii DSM 13941] gi|156233084|gb|ABU57867.1| AMP-dependent synthetase and ligase [Roseiflexus castenholzii DSM 13941] Length=525 Score = 170 bits (431), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 153/496 (31%), Positives = 225/496 (46%), Gaps = 32/496 (6%) Query 42 LRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLP 101 + Y E +V A LRA V +V ++ N PE ACA LGA+AV + L Sbjct 29 ISYAEFTRKVRQAAHGLRALGVEHSDKVALLLGNCPEFLTIFFACAALGAVAVPINPRLK 88 Query 102 IAAIERFCQITDPAAALVA----PGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDA 157 + Q +D +VA P A P+ H + V AV ++TR + H + Sbjct 89 AEEVGYILQNSDSVVLVVADTLLPIIAPALDGCPQLRHIVIVGAVPETSITR-TLHPFTS 147 Query 158 ASLAGN----ADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVV 213 S AG+ A G ED ++I+TSGTTG PK VLL++ + D+ ++ Sbjct 148 LSAAGDHPVSAAVGPEDIASIIYTSGTTGRPKGVLLSHGNYLF--DVWSYATACQISE-- 203 Query 214 GETTYSPLPATHIGG-LWWILTCLMHGG-LCVTGGENTTSLLEILTTNAVATTCLVPTLL 271 + LP H+ + +L+ L GG L + G + L L + VPT+ Sbjct 204 ADRLLCMLPLFHVNAQVASVLSALHQGGALILLEGFSPREFLPALARYRATSFSAVPTIY 263 Query 272 SKLVSELKSANATVPSLRLVGYGGSRAIAADV--RFIEATGVRTAQVYGLSETGCTALCL 329 + L + + + SLR V G+ + +V RF + + YGLSE C + Sbjct 264 AILNNLPDAGQYDLSSLR-VCICGAAPMPVEVFERFEQIYRAFILEGYGLSEGTCVSTLN 322 Query 330 PTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYW 389 P D G KI G++G PG +V + G P PG + G + I+ P M GY+ Sbjct 323 PLD-GRPRKI--GSIGVALPGQEVRIVDDQG-QPVPPG-----TVGEIVIRGPNVMQGYY 373 Query 390 NNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSG 449 NPE TA + DGW+ TGDL R +G+F+I GR EMII GG NI P E++ + Sbjct 374 KNPEATAAAIRDGWLFTGDLGSRDAEGYFFIVGRKKEMIIRGGENIYPKEIEEVLYRHPA 433 Query 450 VREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIV 509 V EAA +PD +G V +VA + SA ++H R P + V Sbjct 434 VAEAAVVGLPDPIWGEQVAAFIVAHPGISVSAETIIEHC-----RAHLADFKCPQVVEFV 488 Query 510 TDIPRTQSGKVMRASL 525 P+T +GK+ + L Sbjct 489 ESFPKTATGKIQKNRL 504 >gi|194291334|ref|YP_002007241.1| long-chain-fatty-acid--CoA ligase [Cupriavidus taiwanensis LMG 19424] gi|193225238|emb|CAQ71180.1| putative AMP-dependent synthetase and ligase, putative o-succinylbenzoate--CoA ligase [Cupriavidus taiwanensis LMG 19424] Length=546 Score = 169 bits (429), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 149/532 (29%), Positives = 235/532 (45%), Gaps = 32/532 (6%) Query 6 FQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSR 65 F + LP V R F AR +PEA+A +G Y +A L A+ + Sbjct 22 FTYLTTLPHAV--RHF--ARLRPEAVAYS-FEGRQTT-YAAFERNTDRVAQALLAEGLRA 75 Query 66 GSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKM 125 G R+ + N + +L K GA+ A L +E D V S Sbjct 76 GDRIGYVGKNSDHYFELLLGAGKTGAVMAPASWRLAPPEVEFILGHCDAVVLFVGAES-- 133 Query 126 ASSAVPEALHSIPVIAVDIAAVTRESEHSL-------DAASLAGNADQ-GSEDPLAMIFT 177 ++ V L ++P++ + + + DA A + + D + ++T Sbjct 134 -AAMVRNLLPALPLVRKVVVMEPCDGQGDWPCYTDWRDAHPATPPAHEPAAHDVVLQLYT 192 Query 178 SGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLM 237 SGTTG PK +L +R ++ ++E L W WV + + +P HIGG W L L+ Sbjct 193 SGTTGRPKGAMLTHRNLTIGTEVSEREHLAWSHWVADDISLVAMPVAHIGGSGWGLRNLL 252 Query 238 HGGLCVTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGS 296 G V E + ++L+ + V+ LVP + ++ + ++ L+ + YG + Sbjct 253 SGAKGVVAREFDPRAVLDFIEHERVSKLFLVPAAMQIVLRDPRARQVDYSRLKYLLYGAA 312 Query 297 RAIAADVRF-IEATGVRTAQVYGLSETGCTALCLPTDDGSIVKI-EAGAVGRPYPGVDVY 354 AA +R IE G Q YG++ET T + LP +D + ++ A G+ PGV++ Sbjct 313 PIPAALLREGIEVFGCGFVQQYGMTETTGTIVALPPEDHTTDEVPRMRAAGKALPGVELK 372 Query 355 LAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERR 413 + +G APG G + ++S NM GYW PE TA + DGW+ TGD Sbjct 373 VVDYEG-RQLAPG-----EVGEVVVRSQHNMAGYWKQPEETARTIDADGWLRTGDAGYMD 426 Query 414 EDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA 473 +G+ YI R +MII GG N+ P EV+ G V + A +PDE++G V VV Sbjct 427 AEGYLYIHDRVKDMIISGGENVYPAEVESAIYGHPQVADVAVIGVPDEKWGEAVKAIVVL 486 Query 474 SAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 + A + I A R+ P +I V +PR SGK++R L Sbjct 487 -----KPGQAADRDAILAWTRQRVAGFKVPKSIEFVDALPRNPSGKLLRRKL 533 >gi|86751180|ref|YP_487676.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris HaA2] gi|86574208|gb|ABD08765.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris HaA2] Length=508 Score = 169 bits (429), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 150/532 (29%), Positives = 238/532 (45%), Gaps = 43/532 (8%) Query 17 LDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNG 76 D + A +P+ IAL L YR L + LA+ L + V RG RV V++ N Sbjct 6 FDWITHHAEVRPDRIALIDLATQRRLTYRALDDRIDRLASHLASLGVGRGDRVAVLAANT 65 Query 77 PETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHS 136 +T AC +LGAI V + L + + + D A ++A S A+ A L S Sbjct 66 TDTLEVQFACFRLGAIFVPLNVRLTVHELSFI--VGDAAPLVLAHDSDFAAMA--GDLQS 121 Query 137 IPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMI-FTSGTTGEPKAVLLANRTFF 195 IA + E +L AA A+ + D ++ I +TSGTTG+PK ++ + F Sbjct 122 KCGIA-HLLQFGAPYEAALSAAPRLARAEAVTLDDVSTIMYTSGTTGKPKGAMITHLMTF 180 Query 196 AVPDILQKEGLNWVTWVVGETTY-SPLPATHIGGLWWILTCLMHGG--LCVTGGENTTSL 252 + L ++ T + +P H GGL ++H G + + + Sbjct 181 -----INAVNLGIPAFITQRTVFLCVMPLFHTGGLNCYTNPVLHAGGTVILMRAFDPGET 235 Query 253 LEILTTNAVATTCL--VPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATG 310 L ++ + T VP++ + A+ + L++ G GG+ +R + G Sbjct 236 LRLIGDAGIGLTHFFGVPSIYQFMCQHPAFADTDLSRLQMAGVGGAPMPVPLLRIWQERG 295 Query 311 VRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGP 370 Q YG++ET + L +DD + +AG+ G+P D+ + DG P APG Sbjct 296 CTLVQGYGMTETSPAVMMLDSDDAAR---KAGSAGKPVLHADLKIVGPDG-EPVAPG--- 348 Query 371 SASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIIC 430 G LW+K P GYWN PE DGW++TGD +GF+YI R+ +M I Sbjct 349 --EMGELWVKGPNITPGYWNRPEANRTSFTDGWLHTGDAARVDGEGFYYIVDRTKDMYIS 406 Query 431 GGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA---SAELDESAARALKH 487 GG N+ P EV+ + + + EAA PD ++G G+A++A +L E+ Sbjct 407 GGENVYPAEVEDVLYQLPEIAEAAVIGAPDPQWGE-TGVAIIAVKTGHDLPEAKLHTHCR 465 Query 488 TIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVR 539 ARF+ P +V V +PR +GKV + +L + R +VR Sbjct 466 ERLARFK-------CPQRVVFVEALPRNATGKVHKPTL-------RERFLVR 503 >gi|315442419|ref|YP_004075298.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|315260722|gb|ADT97463.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=509 Score = 169 bits (428), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 158/529 (30%), Positives = 240/529 (46%), Gaps = 36/529 (6%) Query 18 DRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGP 77 D V R +P+A AL D T + YREL A V G RV + NG Sbjct 7 DIVRSHGRNRPDAPALIVGDRT--VSYRELDERSNRTAQAFSRTGVGPGDRVAFVERNGI 64 Query 78 ETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMAS--SAVPEALH 135 E + AKLGA+AV N + A E I D A++V G + + + L Sbjct 65 EFFDVAFGSAKLGAVAVPV--NWRLTAPEMRHVIADCGASVVVVGQEFTDHLDVIADEL- 121 Query 136 SIPVIAVDIAAVTRESEHSLDAA-SLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTF 194 + V+ + + + E L A S+ G +D + +++TSGTTG PK V+L+N Sbjct 122 DVEVVVIGNHSRWPDFEGWLAAQPSVDPGVVTGPDDLVFLMYTSGTTGAPKGVMLSNANV 181 Query 195 FAVPDILQKEGLN--WVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGE-NTTS 251 + + G+ W + + + +P H+ G W L L G + V + + + Sbjct 182 -----VCKTAGVGGPW-KFDADSVSLAVMPLFHMAGFGWALAGLWEGAVTVVLRDVDPGA 235 Query 252 LLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADV--RFIEAT 309 +L+ + + V LVP ++ L+ + + LR+V YG S I DV R I+ Sbjct 236 ILDAVARHRVTNMLLVPAVIQFLLDTPGLDDTDLSRLRIVVYGAS-PITDDVLMRGIDRF 294 Query 310 GVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAG 369 G AQVYG++E+ + L D+ + + GRPYP V + + + PT Sbjct 295 GGIFAQVYGMTESTGSVTQLDGDEHLPQLLRS--CGRPYPWVQIRV-----VDPTGRDVA 347 Query 370 PSASFGTLWIKSPANMLGYWNNPERTAEVLI-DGWVNTGDLLERREDGFFYIKGRSSEMI 428 P + G +W +S NMLGYWNNPE TA L DGW+ TGD DG+ Y+ R +MI Sbjct 348 P-GTVGEVWTRSDQNMLGYWNNPEATAATLTPDGWLRTGDAGYLDRDGYLYLHDRIKDMI 406 Query 429 ICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHT 488 + G N+ P EV+ + V + A IPD +G V VVA A + E+ A Sbjct 407 VSGAENVYPAEVENVLMTHPAVTDVAVIGIPDTRWGEAVKAVVVAGAPVTEAELIAFARE 466 Query 489 IAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 A F+ P ++ V +PR SGK+++ L D+ R + Sbjct 467 QLAGFK-------LPKSVDFVDALPRNPSGKLLKRQLREPYWTDEDRHI 508 >gi|333370466|ref|ZP_08462468.1| long-chain-fatty-acid-CoA ligase [Desmospora sp. 8437] gi|332977814|gb|EGK14571.1| long-chain-fatty-acid-CoA ligase [Desmospora sp. 8437] Length=552 Score = 169 bits (427), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 148/528 (29%), Positives = 226/528 (43%), Gaps = 49/528 (9%) Query 22 EQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYL 81 ++AR P+ A+ G +RYRE V LA L + +G R+ ++ N L Sbjct 53 DRARLSPDMEAI--VSGNRRIRYREYNHMVNQLAHYLLESRIEKGDRIAILCKNQYPMPL 110 Query 82 SVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIA 141 LA AK+GAI V + + + + P K + LH + + Sbjct 111 IYLAAAKIGAITVPLNWRMKTDELRWILEDCRPRILFYDDDFK----QILPLLHELDFLE 166 Query 142 VDIAAVTRESEH----SLDAASLAG--NADQGSEDPLAMIFTSGTTGEPKAVLLANRTFF 195 I E+ H L +A G + EDP +I+TSGTTG PK V+ + + Sbjct 167 QQIRVGDGETIHPFFEDLYSARPGGEPKVEVHEEDPALIIYTSGTTGRPKGVVNNHANIY 226 Query 196 A-------VPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGE- 247 A D+ K+ +VT P HI G+ ++L +M G V + Sbjct 227 AAGVANTNTLDLRYKDRFLFVT-----------PLFHISGMMFMLAPIMRGFTLVLETQF 275 Query 248 NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIE 307 + + E+L + VP +L+ ++ LK VPSLR + GGS A +R + Sbjct 276 HPLKIWELLQAEQITGMMSVPVILNYMMEGLKVQEVDVPSLRTILCGGSLVPAPLIRVMF 335 Query 308 ATGVRTAQVYGLSET-GCTALCLPTDDGSIVKIEA-GAVGRPYPGVDVYLAATDGIGPTA 365 G QVYG +ET G +P D G IE +VG P + + A I P+ Sbjct 336 ELGYHVVQVYGATETSGAITYWMP-DMG----IETCNSVG---PAI--FHAEIKIIDPST 385 Query 366 PGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSS 425 A P G + +SP GYWN P+ T +VL +GW +TGDL E+GF +I R Sbjct 386 GEALPHGEIGEIICRSPVLFAGYWNRPQETEKVLKNGWYHTGDLGWMEENGFLHIVDRLK 445 Query 426 EMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARAL 485 +++I GG + P +V+ + + + GV E A + E +G L VV E S L Sbjct 446 DVVITGGEKVFPAQVESVLQQLEGVAETAVVGVRHEVWGELARAYVVLKEEAVLSEEDLL 505 Query 486 KHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADK 533 H R+ +V V ++P+ GKV++ L A + Sbjct 506 AHA------RKHLADHNLHDVVFVKELPKNSMGKVLKFVLREHANQEN 547 >gi|91978271|ref|YP_570930.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris BisB5] gi|91684727|gb|ABE41029.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris BisB5] Length=508 Score = 169 bits (427), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 149/518 (29%), Positives = 229/518 (45%), Gaps = 36/518 (6%) Query 17 LDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNG 76 D + A +P+ AL L YR L V LA+ L V RG RV V++ N Sbjct 6 FDWINHHAEVRPDRTALIDLATQRRLTYRALDDRVDRLASHLATLGVGRGDRVAVLAANT 65 Query 77 PETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHS 136 ET AC +LGAI V + L + + P S+ + L + Sbjct 66 TETLEVQFACFRLGAIFVPLNIRLTVHELAFILGDATPRVLT----HDQDSAVMAHELQT 121 Query 137 IPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMI-FTSGTTGEPKAVLLANRTFF 195 IA + A E +L + G A+ + D ++ I +TSGTTG+PK ++ + F Sbjct 122 KCTIA-HLLAFGAPYEAALANSPRLGAAEAVTLDDVSTIMYTSGTTGKPKGAMITHGMTF 180 Query 196 AVPDILQKEGLNWVTWVVGETTY-SPLPATHIGGLWWILTCLMHGG--LCVTGGENTTSL 252 + L +V T + LP H GGL ++H G + + + + Sbjct 181 -----INAVNLGIPAFVSQRTVFLCVLPLFHTGGLNCYTNPVLHAGGTVILMRAFDPGAA 235 Query 253 LEILTTNAVATTCL--VPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATG 310 L+I+ A+ T VP++ + A + L+L G GG+ +R + G Sbjct 236 LKIIGDPAIGLTHFFGVPSIYQFMCQHPAFAETDLSRLQLAGVGGASMPVPLLRIWQDRG 295 Query 311 VRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGP 370 Q YG++ET L L +DD + +AG+ G+P D+ + DG P PG Sbjct 296 CALVQGYGMTETSPAVLMLDSDDAAR---KAGSAGKPVLHADLKIVGVDG-EPVNPG--- 348 Query 371 SASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIIC 430 G LW+K P GYWN P+ DGW++TGD ++GF+YI R+ +M I Sbjct 349 --DMGELWVKGPNITPGYWNRPDANRTSFTDGWLHTGDAARVDDEGFYYIVDRTKDMYIS 406 Query 431 GGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVA---SAELDESAARALKH 487 GG N+ P EV+ + + V EAA PD ++G G+A++A +L E+ A Sbjct 407 GGENVYPAEVEDVLYQLPEVAEAAVIGAPDPQWGE-TGVAIIAIKNGHDLPETKLLAHCR 465 Query 488 TIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASL 525 ARF+ P +V V +PR +GKV + +L Sbjct 466 ERLARFK-------CPQRVVFVEALPRNATGKVHKPTL 496 >gi|146339585|ref|YP_001204633.1| long-chain-fatty-acid--CoA ligase [Bradyrhizobium sp. ORS 278] gi|146192391|emb|CAL76396.1| Putative long-chain fatty-acid-CoA ligase [Bradyrhizobium sp. ORS 278] Length=526 Score = 168 bits (426), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 154/535 (29%), Positives = 237/535 (45%), Gaps = 28/535 (5%) Query 14 STVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVIS 73 ST++D V QA+ A A ++ + E + +A L+A + G R+ Sbjct 8 STLVDVVRSQAQALGSATAYEFEGRITS--FAEFDRKTNQVANALKALGLKPGERIAYFG 65 Query 74 DNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMAS--SAVP 131 N + Y +L A + A VMA N +A E + D A ++ G + + + Sbjct 66 KNS-DIYFELLVGA-MKANVVMAPVNWRLAGPEVAFIVEDCKAPVLFVGPEFITMIRQIR 123 Query 132 EALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQ-----GSEDPLAMIFTSGTTGEPKA 186 + L S+ I +++ A A AD +D ++TSGTTG+PK Sbjct 124 DQLPSVRQIITTEGGAPEWQDYT--AWRDAQRADDPGVAITPKDIALQLYTSGTTGKPKG 181 Query 187 VLLANRTFFAVPDILQ-KEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTG 245 +L++ F + + +E +W W + + +P HIGG W L L HG V Sbjct 182 AMLSHANFLNLVNTSNPEEKPDWNKWSTDDVSLIAMPIFHIGGSGWGLMSLYHGARGVIA 241 Query 246 GE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVR 304 E + T +L+ + + +VP + +V + ++ L+ + YG S AA ++ Sbjct 242 REFDPTKILDFFEQSGITKLFMVPAAMQFVVRQPRARQVDFSRLKYMLYGASPIPAALLK 301 Query 305 -FIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGP 363 I+ Q+YG++ET T + LP +D + G+P PGV+V A D +G Sbjct 302 ECIDVFKCGFVQMYGMTETTGTIVALPPEDHVEGLERMRSAGKPLPGVEV--AIIDPLG- 358 Query 364 TAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERREDGFFYIKG 422 P G + +S +NM GYWN PE TA L DGW+ TGD EDG+ YI Sbjct 359 ---NPLPPREVGEIATRSGSNMAGYWNLPEATARTLGKDGWLRTGDAGYMDEDGYVYIHD 415 Query 423 RSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAA 482 R +MII GG NI P EV+ V EAA IPD+++G V VV +A Sbjct 416 RIKDMIISGGENIYPAEVESAICDHPDVAEAAVIGIPDDKWGEAVKAIVVMKPGKQATAT 475 Query 483 RALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVV 537 + T R P T+ + +PR SGK++R +L A K R V Sbjct 476 DIINFT-----RTRIAGFKTPKTVDFLDALPRNPSGKILRRNLRDPYWAGKDRQV 525 >gi|148254372|ref|YP_001238957.1| long-chain-fatty-acid--CoA ligase [Bradyrhizobium sp. BTAi1] gi|146406545|gb|ABQ35051.1| Putative long-chain fatty-acid-CoA ligase [Bradyrhizobium sp. BTAi1] Length=526 Score = 168 bits (425), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 159/541 (30%), Positives = 241/541 (45%), Gaps = 40/541 (7%) Query 14 STVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVIS 73 ST++D V +QA+ A A ++ + E + +A L+A V R+ Sbjct 8 STLVDIVRKQAQALGSATAYEFEGRVTS--FAEFDRKTNQVANALKALGVKPHERIAYFG 65 Query 74 DNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEA 133 N + Y +L A + A VMA N +A E + D A ++ G PE Sbjct 66 KNS-DIYFELLVGA-MKANVVMAPINWRLAGPEVAFIVEDCKAPVLFVG--------PEF 115 Query 134 LHSIPVIAVDIAAV----TRESEHSLDAASLAGNADQGSEDP--------LAM-IFTSGT 180 + I I+ +I +V T E A Q +EDP +A+ ++TSGT Sbjct 116 ITMIRNISGEIPSVRHIITTEGGAPEWQDYTAWRDVQSAEDPGVPITPKDIALQLYTSGT 175 Query 181 TGEPKAVLLANRTFFAVPDILQK-EGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHG 239 TG+PK +L++ F + + + +W W + + +P HIGG W L L HG Sbjct 176 TGKPKGAMLSHANFLNLVNTGDPADRPDWNKWSTDDVSLIAMPIFHIGGSGWGLMSLYHG 235 Query 240 GLCVTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRA 298 V E + T +L+ + + +VP + +V + ++ L+ + YG S Sbjct 236 ARGVIAREFDPTKILDFFEQSGITKLFMVPAAMQFVVRQPRARQVDFSRLKYMLYGASPI 295 Query 299 IAADVR-FIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAA 357 AA ++ IE Q+YG++ET T + LP +D + G+P PG++V A Sbjct 296 PAALLKECIEVFKCGFVQMYGMTETTGTIIALPPEDHVEGLERMRSAGKPLPGIEV--AI 353 Query 358 TDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERREDG 416 D +G P G + +S +NM GYWN PE TA L DGW+ TGD EDG Sbjct 354 IDPLG----NPLPPRQVGEIATRSGSNMAGYWNLPEATARTLGKDGWLRTGDAGYMDEDG 409 Query 417 FFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAE 476 + YI R +MII GG NI P EV+ + EAA IPD+++G V VV Sbjct 410 YVYIHDRIKDMIISGGENIYPAEVESAICDHPDIAEAAVIGIPDDKWGEAVKAIVVM--- 466 Query 477 LDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARV 536 + RA I R P ++ + +PR SGK++R +L A A K R Sbjct 467 --KPGKRATATDIINFTRTRIAGFKTPKSVDFLDALPRNPSGKILRRTLRAPYWAGKDRQ 524 Query 537 V 537 V Sbjct 525 V 525 >gi|90423185|ref|YP_531555.1| long-chain-fatty-acid--CoA ligase [Rhodopseudomonas palustris BisB18] gi|90105199|gb|ABD87236.1| AMP-dependent synthetase and ligase [Rhodopseudomonas palustris BisB18] Length=526 Score = 167 bits (422), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 158/541 (30%), Positives = 234/541 (44%), Gaps = 38/541 (7%) Query 13 PSTVLDRVFEQARQQPEAIAL----RRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSR 68 P+T+ D V QA + +AIA RR + R+ VA L A + G R Sbjct 7 PTTLADVVRAQATARGDAIAFEFEGRRTSFAALDRHSNRVARA------LLAAGIQPGQR 60 Query 69 VLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASS 128 + + N + Y +L A + A VMA N +A E + D AA + G + + Sbjct 61 ISYLGKNS-DVYFELLLGA-MKANVVMAPVNWRLAPPEIAFIVNDCQAAALFVGPEFVA- 117 Query 129 AVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQ------GSEDPLAMIFTSGTTG 182 AV +P + IA +E AA +D G D ++TSGTTG Sbjct 118 AVGALAAQLPGVKTFIATEGGAAEWPDYAAWRDAQSDDAPAIALGPRDVAIQLYTSGTTG 177 Query 183 EPKAVLLANRTFFAVPDILQK-EGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGL 241 PK +L++ F A+ + E W W + + +P HIGG W + + HG Sbjct 178 HPKGAMLSHANFLALVRAGKDAEQPQWNQWREDDVSLVAMPVFHIGGSGWGVMGVYHGVK 237 Query 242 CVTGGE-NTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIA 300 V E + +L+ T + LVP + +V + ++ LR + YG S A Sbjct 238 GVIAREFDPHKILDFFGTFGITRVFLVPAAMQFVVRQPRAREMDFSKLRYMLYGASPIPA 297 Query 301 ADVRFIEAT-GVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATD 359 A ++ A Q+YG++ET T + LP +D A G+ PGV++ + D Sbjct 298 ALLKECLALFKCGFVQMYGMTETTGTIVALPPEDHIEGSERMRAAGKALPGVELAILDPD 357 Query 360 GIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVL-IDGWVNTGDLLERREDGFF 418 G P G + +S NM+GYWN P+ TA+ + D W+ TGD EDG+ Sbjct 358 G------NRLPPRQVGEIATRSGCNMVGYWNLPDATAKTIDADNWLRTGDAGYLDEDGYL 411 Query 419 YIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELD 478 YI R +MII GG NI P EV+ + E A +PDE +G V VV Sbjct 412 YIHDRIKDMIISGGENIYPAEVESALNDHPDIAEVAVVGVPDEIWGEAVKAVVVMKPGKQ 471 Query 479 ESAAR--ALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARV 536 SA A H A+F+ P T+ + +PR +GK++R +L A K R Sbjct 472 ASAHDVIAFAHQRIAKFK-------SPRTVDFIAALPRNGAGKILRRALREPYWAGKQRR 524 Query 537 V 537 V Sbjct 525 V 525 Lambda K H 0.317 0.133 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1189573419810 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40