BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0101 Length=2512 Score E Sequences producing significant alignments: (Bits) Value gi|15839481|ref|NP_334518.1| peptide synthetase, putative [Mycob... 5038 0.0 gi|15607243|ref|NP_214615.1| peptide synthetase [Mycobacterium t... 5033 0.0 gi|254233496|ref|ZP_04926822.1| peptide synthetase nrp [Mycobact... 5033 0.0 gi|121636014|ref|YP_976237.1| putative peptide synthetase nrp [M... 5033 0.0 gi|254549035|ref|ZP_05139482.1| peptide synthetase, putative [My... 5032 0.0 gi|148821293|ref|YP_001286047.1| peptide synthetase nrp [Mycobac... 5032 0.0 gi|339296816|gb|AEJ48926.1| putative peptide synthetase nrp [Myc... 5032 0.0 gi|289445631|ref|ZP_06435375.1| peptide synthetase nrp [Mycobact... 5031 0.0 gi|289760200|ref|ZP_06519578.1| peptide synthetase [Mycobacteriu... 5031 0.0 gi|289756163|ref|ZP_06515541.1| peptide synthetase [Mycobacteriu... 5030 0.0 gi|253797019|ref|YP_003030020.1| peptide synthetase nrp [Mycobac... 5030 0.0 gi|339630185|ref|YP_004721827.1| peptide synthetase [Mycobacteri... 5026 0.0 gi|340625137|ref|YP_004743589.1| putative peptide synthetase [My... 5019 0.0 gi|148659864|ref|YP_001281387.1| putative peptide synthetase [My... 4821 0.0 gi|289572681|ref|ZP_06452908.1| LOW QUALITY PROTEIN: peptide syn... 4474 0.0 gi|308373889|ref|ZP_07667680.1| peptide synthetase nrp [Mycobact... 4181 0.0 gi|289441470|ref|ZP_06431214.1| peptide synthetase nrp [Mycobact... 3473 0.0 gi|339293168|gb|AEJ45279.1| peptide synthetase nrp [Mycobacteriu... 3219 0.0 gi|289764217|ref|ZP_06523595.1| hypothetical protein TBIG_00526 ... 2498 0.0 gi|296164404|ref|ZP_06846979.1| syringomycin synthetase [Mycobac... 2109 0.0 gi|342860889|ref|ZP_08717539.1| syringomycin synthetase [Mycobac... 2025 0.0 gi|254822780|ref|ZP_05227781.1| syringomycin synthetase [Mycobac... 2023 0.0 gi|254775687|ref|ZP_05217203.1| hypothetical protein MaviaA2_136... 2015 0.0 gi|118465061|ref|YP_882421.1| syringomycin synthetase [Mycobacte... 2006 0.0 gi|240169631|ref|ZP_04748290.1| hypothetical protein MkanA1_0997... 1968 0.0 gi|336457976|gb|EGO36964.1| amino acid adenylation enzyme/thioes... 1925 0.0 gi|41407340|ref|NP_960176.1| hypothetical protein MAP1242 [Mycob... 1924 0.0 gi|289764218|ref|ZP_06523596.1| PstD [Mycobacterium tuberculosis... 1884 0.0 gi|339293167|gb|AEJ45278.1| peptide synthetase, putative [Mycoba... 1649 0.0 gi|254775689|ref|ZP_05217205.1| linear gramicidin synthetase sub... 1511 0.0 gi|5524341|gb|AAD44234.1|AF143772_40 PstB [Mycobacterium avium] 1509 0.0 gi|254819610|ref|ZP_05224611.1| linear gramicidin synthetase sub... 1507 0.0 gi|296164632|ref|ZP_06847199.1| linear gramicidin synthetase sub... 1506 0.0 gi|118462635|ref|YP_882425.1| linear gramicidin synthetase subun... 1505 0.0 gi|342858826|ref|ZP_08715481.1| linear gramicidin synthetase sub... 1474 0.0 gi|296164403|ref|ZP_06846978.1| linear gramicidin synthetase sub... 1467 0.0 gi|41407518|ref|NP_960354.1| hypothetical protein MAP1420 [Mycob... 1466 0.0 gi|254823419|ref|ZP_05228420.1| linear gramicidin synthetase sub... 1457 0.0 gi|254775508|ref|ZP_05217024.1| linear gramicidin synthetase sub... 1453 0.0 gi|336462021|gb|EGO40870.1| amino acid adenylation enzyme/thioes... 1450 0.0 gi|118463736|ref|YP_882241.1| linear gramicidin synthetase subun... 1446 0.0 gi|342860686|ref|ZP_08717336.1| linear gramicidin synthetase sub... 1436 0.0 gi|41407968|ref|NP_960804.1| hypothetical protein MAP1870c [Myco... 1419 0.0 gi|342859838|ref|ZP_08716491.1| hypothetical protein MCOL_13203 ... 1404 0.0 gi|118468008|ref|YP_884815.1| linear gramicidin synthetase subun... 1396 0.0 gi|5869932|emb|CAB55600.1| peptide synthetase [Mycobacterium sme... 1393 0.0 gi|254822516|ref|ZP_05227517.1| linear gramicidin synthetase sub... 1384 0.0 gi|169631764|ref|YP_001705413.1| non-ribosomal peptide synthetas... 1376 0.0 gi|169631176|ref|YP_001704825.1| peptide synthetase NRP [Mycobac... 1358 0.0 gi|254775688|ref|ZP_05217204.1| syringomycin synthetase [Mycobac... 1358 0.0 >gi|15839481|ref|NP_334518.1| peptide synthetase, putative [Mycobacterium tuberculosis CDC1551] gi|13879157|gb|AAK44332.1| peptide synthetase, putative [Mycobacterium tuberculosis CDC1551] Length=2520 Score = 5038 bits (13068), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2512/2512 (100%), Positives = 2512/2512 (100%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 9 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 68 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 69 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 128 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 129 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 188 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 189 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 248 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 249 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 308 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 309 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 368 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 369 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 428 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 429 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 488 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 489 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 548 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 549 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 608 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 609 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 668 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 669 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 728 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 729 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 788 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 789 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 848 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 849 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 908 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 909 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 968 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 969 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1028 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1029 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1088 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1089 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1148 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1149 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1208 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1209 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1268 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1269 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1328 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1329 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1388 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1389 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1448 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1449 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1508 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1509 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1568 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1569 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1628 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1629 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1688 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1689 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1748 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1749 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1808 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1809 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1868 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1869 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1928 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1929 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1988 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1989 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2048 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2049 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2108 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2109 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2168 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2169 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2228 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2229 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2288 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2289 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2348 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2349 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2408 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2409 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2468 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2469 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2520 >gi|15607243|ref|NP_214615.1| peptide synthetase [Mycobacterium tuberculosis H37Rv] gi|31791279|ref|NP_853772.1| peptide synthetase [Mycobacterium bovis AF2122/97] gi|167968259|ref|ZP_02550536.1| peptide synthetase nrp [Mycobacterium tuberculosis H37Ra] 36 more sequence titles Length=2512 Score = 5033 bits (13056), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2511/2512 (99%), Positives = 2512/2512 (100%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|254233496|ref|ZP_04926822.1| peptide synthetase nrp [Mycobacterium tuberculosis C] gi|124603289|gb|EAY61564.1| peptide synthetase nrp [Mycobacterium tuberculosis C] Length=2512 Score = 5033 bits (13055), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2512/2512 (100%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTV+AEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVNAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|121636014|ref|YP_976237.1| putative peptide synthetase nrp [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988487|ref|YP_002643174.1| putative peptide synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|121491661|emb|CAL70119.1| Probable peptide synthetase nrp [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224771600|dbj|BAH24406.1| putative peptide synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|341600030|emb|CCC62698.1| probable peptide synthetase nrp [Mycobacterium bovis BCG str. Moreau RDJ] Length=2512 Score = 5033 bits (13054), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2512/2512 (100%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRA+THHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRAMTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|254549035|ref|ZP_05139482.1| peptide synthetase, putative [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=2512 Score = 5032 bits (13053), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2512/2512 (100%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 +APRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 LAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|148821293|ref|YP_001286047.1| peptide synthetase nrp [Mycobacterium tuberculosis F11] gi|148719820|gb|ABR04445.1| peptide synthetase nrp [Mycobacterium tuberculosis F11] Length=2512 Score = 5032 bits (13053), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2511/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAG AVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGFAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|339296816|gb|AEJ48926.1| putative peptide synthetase nrp [Mycobacterium tuberculosis CCDC5180] Length=2512 Score = 5032 bits (13052), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2511/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVE LTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVETLTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|289445631|ref|ZP_06435375.1| peptide synthetase nrp [Mycobacterium tuberculosis CPHL_A] gi|289418589|gb|EFD15790.1| peptide synthetase nrp [Mycobacterium tuberculosis CPHL_A] Length=2512 Score = 5031 bits (13050), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2511/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRH 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|289760200|ref|ZP_06519578.1| peptide synthetase [Mycobacterium tuberculosis T85] gi|289715764|gb|EFD79776.1| peptide synthetase [Mycobacterium tuberculosis T85] Length=2512 Score = 5031 bits (13049), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2511/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAG ATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGSATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|289756163|ref|ZP_06515541.1| peptide synthetase [Mycobacterium tuberculosis EAS054] gi|289696750|gb|EFD64179.1| peptide synthetase [Mycobacterium tuberculosis EAS054] Length=2512 Score = 5030 bits (13047), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2509/2512 (99%), Positives = 2511/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPE EAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPETEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEA+LGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEANLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|253797019|ref|YP_003030020.1| peptide synthetase nrp [Mycobacterium tuberculosis KZN 1435] gi|289552352|ref|ZP_06441562.1| peptide synthetase nrp [Mycobacterium tuberculosis KZN 605] gi|297632574|ref|ZP_06950354.1| peptide synthetase, putative [Mycobacterium tuberculosis KZN 4207] gi|297729548|ref|ZP_06958666.1| peptide synthetase, putative [Mycobacterium tuberculosis KZN R506] gi|313656875|ref|ZP_07813755.1| peptide synthetase, putative [Mycobacterium tuberculosis KZN V2475] gi|253318522|gb|ACT23125.1| peptide synthetase nrp [Mycobacterium tuberculosis KZN 1435] gi|289436984|gb|EFD19477.1| peptide synthetase nrp [Mycobacterium tuberculosis KZN 605] gi|328456808|gb|AEB02231.1| peptide synthetase nrp [Mycobacterium tuberculosis KZN 4207] Length=2512 Score = 5030 bits (13047), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2510/2512 (99%), Positives = 2511/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLD ARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDPARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|339630185|ref|YP_004721827.1| peptide synthetase [Mycobacterium africanum GM041182] gi|339329541|emb|CCC25176.1| putative peptide synthetase Nrp (peptide synthase) [Mycobacterium africanum GM041182] Length=2512 Score = 5026 bits (13038), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2508/2512 (99%), Positives = 2510/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGH+ELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHNELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLR RLAGHDLPIIDVVDALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRPRLAGHDLPIIDVVDALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDL ALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLGALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|340625137|ref|YP_004743589.1| putative peptide synthetase [Mycobacterium canettii CIPT 140010059] gi|340003327|emb|CCC42445.1| putative peptide synthetase NRP (peptide synthase) [Mycobacterium canettii CIPT 140010059] Length=2512 Score = 5019 bits (13018), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2504/2512 (99%), Positives = 2506/2512 (99%), Gaps = 0/2512 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSAD HLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADAHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEA HGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEACHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASV DVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVCDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQL VVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLTVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTT+DGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTVDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEG EPAGIGGAVEYRTDVFEAQAID Sbjct 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGGEPAGIGGAVEYRTDVFEAQAID 1440 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDV DALAAY Sbjct 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVADALAAY 1620 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 >gi|148659864|ref|YP_001281387.1| putative peptide synthetase [Mycobacterium tuberculosis H37Ra] gi|308394535|ref|ZP_07491683.2| putative AMP-binding enzyme [Mycobacterium tuberculosis SUMu012] gi|148504016|gb|ABQ71825.1| putative peptide synthetase [Mycobacterium tuberculosis H37Ra] gi|308367692|gb|EFP56543.1| putative AMP-binding enzyme [Mycobacterium tuberculosis SUMu012] Length=2410 Score = 4821 bits (12506), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2409/2410 (99%), Positives = 2410/2410 (100%), Gaps = 0/2410 (0%) Query 103 VRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLR 162 +RHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLR Sbjct 1 MRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLR 60 Query 163 EAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNA 222 EAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNA Sbjct 61 EAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNA 120 Query 223 FDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNS 282 FDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNS Sbjct 121 FDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNS 180 Query 283 VAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIR 342 VAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIR Sbjct 181 VAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIR 240 Query 343 EPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAE 402 EPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAE Sbjct 241 EPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAE 300 Query 403 RIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFL 462 RIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFL Sbjct 301 RIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFL 360 Query 463 GRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVR 522 GRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVR Sbjct 361 GRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVR 420 Query 523 TNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSG 582 TNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSG Sbjct 421 TNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSG 480 Query 583 TTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV 642 TTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV Sbjct 481 TTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV 540 Query 643 RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAI 702 RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAI Sbjct 541 RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAI 600 Query 703 RCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTV 762 RCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTV Sbjct 601 RCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTV 660 Query 763 FLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRK 822 FLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRK Sbjct 661 FLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRK 720 Query 823 DAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRI 882 DAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRI Sbjct 721 DAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRI 780 Query 883 RLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIW 942 RLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIW Sbjct 781 RLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIW 840 Query 943 SRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTP 1002 SRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTP Sbjct 841 SRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTP 900 Query 1003 DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEAL 1062 DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEAL Sbjct 901 DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEAL 960 Query 1063 GAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAA 1122 GAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAA Sbjct 961 GAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAA 1020 Query 1123 RHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAP 1182 RHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAP Sbjct 1021 RHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAP 1080 Query 1183 DWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVA 1242 DWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVA Sbjct 1081 DWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVA 1140 Query 1243 DQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR 1302 DQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR Sbjct 1141 DQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR 1200 Query 1303 SDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPT 1362 SDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPT Sbjct 1201 SDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPT 1260 Query 1363 RALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAG 1422 RALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAG Sbjct 1261 RALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAG 1320 Query 1423 IGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRA 1482 IGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRA Sbjct 1321 IGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRA 1380 Query 1483 VLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPG 1542 VLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPG Sbjct 1381 VLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPG 1440 Query 1543 ECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSR 1602 ECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSR Sbjct 1441 ECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSR 1500 Query 1603 LAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS 1662 LAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS Sbjct 1501 LAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS 1560 Query 1663 LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS Sbjct 1561 LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1620 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA Sbjct 1621 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1680 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF Sbjct 1681 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1740 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG Sbjct 1741 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1800 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV Sbjct 1801 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1860 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA Sbjct 1861 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 1920 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASD 2082 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASD Sbjct 1921 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASD 1980 Query 2083 LTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVR 2142 LTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVR Sbjct 1981 LTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVR 2040 Query 2143 AESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETV 2202 AESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETV Sbjct 2041 AESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETV 2100 Query 2203 DLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTE 2262 DLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTE Sbjct 2101 DLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTE 2160 Query 2263 DADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQ 2322 DADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQ Sbjct 2161 DADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQ 2220 Query 2323 LNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGS 2382 LNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGS Sbjct 2221 LNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGS 2280 Query 2383 SLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRR 2442 SLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRR Sbjct 2281 SLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRR 2340 Query 2443 HSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINY 2502 HSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINY Sbjct 2341 HSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINY 2400 Query 2503 VTNLQLLGLL 2512 VTNLQLLGLL Sbjct 2401 VTNLQLLGLL 2410 >gi|289572681|ref|ZP_06452908.1| LOW QUALITY PROTEIN: peptide synthetase nrp [Mycobacterium tuberculosis K85] gi|289537112|gb|EFD41690.1| LOW QUALITY PROTEIN: peptide synthetase nrp [Mycobacterium tuberculosis K85] Length=2283 Score = 4474 bits (11603), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2236/2239 (99%), Positives = 2238/2239 (99%), Gaps = 0/2239 (0%) Query 274 NVATCLVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHV 333 +VATCLVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHV Sbjct 45 HVATCLVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHV 104 Query 334 EALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPA 393 EALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPA Sbjct 105 EALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPA 164 Query 394 CKTHPKVAERIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLD 453 CKTHPKVAERIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLD Sbjct 165 CKTHPKVAERIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLD 224 Query 454 SARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVC 513 SARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVC Sbjct 225 SARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVC 284 Query 514 DTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATK 573 DTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGH+ELRKVVDERVTQVTHDALLATK Sbjct 285 DTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHNELRKVVDERVTQVTHDALLATK 344 Query 574 TAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFG 633 TAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFG Sbjct 345 TAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFG 404 Query 634 GAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLR 693 GAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLR Sbjct 405 GAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLR 464 Query 694 QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRL 753 QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRL Sbjct 465 QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRL 524 Query 754 GRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE 813 GRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE Sbjct 525 GRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE 584 Query 814 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGE 873 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGE Sbjct 585 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGE 644 Query 874 QDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ 933 QDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ Sbjct 645 QDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ 704 Query 934 RAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAA 993 RAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAA Sbjct 705 RAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAA 764 Query 994 NLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRL 1053 NLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRL Sbjct 765 NLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRL 824 Query 1054 RGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADR 1113 RGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADR Sbjct 825 RGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADR 884 Query 1114 LQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAY 1173 LQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAY Sbjct 885 LQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAY 944 Query 1174 ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLP 1233 ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLP Sbjct 945 ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLP 1004 Query 1234 TARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDV 1293 TARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDV Sbjct 1005 TARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDV 1064 Query 1294 AVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFE 1353 AVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFE Sbjct 1065 AVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFE 1124 Query 1354 VLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAER 1413 VLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAER Sbjct 1125 VLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAER 1184 Query 1414 FSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERA 1473 FSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERA Sbjct 1185 FSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERA 1244 Query 1474 RLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHR 1533 RLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHR Sbjct 1245 RLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHR 1304 Query 1534 LAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAA 1593 LAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAA Sbjct 1305 LAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAA 1364 Query 1594 VTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITH 1653 VTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITH Sbjct 1365 VTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITH 1424 Query 1654 RNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFH 1713 RNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFH Sbjct 1425 RNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFH 1484 Query 1714 GLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTE 1773 GLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTE Sbjct 1485 GLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTE 1544 Query 1774 TTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWR 1833 TTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWR Sbjct 1545 TTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWR 1604 Query 1834 RAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVAT 1893 RAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVAT Sbjct 1605 RAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVAT 1664 Query 1894 ALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVV 1953 ALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVV Sbjct 1665 ALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVV 1724 Query 1954 VIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFF 2013 VIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFF Sbjct 1725 VIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFF 1784 Query 2014 ELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGD 2073 ELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGD Sbjct 1785 ELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGD 1844 Query 2074 NPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV 2133 NPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV Sbjct 1845 NPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV 1904 Query 2134 DGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQP 2193 DGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQP Sbjct 1905 DGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQP 1964 Query 2194 MWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGA 2253 MWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGA Sbjct 1965 MWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGA 2024 Query 2254 AIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMI 2313 AIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDL ALPVAVFRCGMI Sbjct 2025 AIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLGALPVAVFRCGMI 2084 Query 2314 LADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIA 2373 LADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIA Sbjct 2085 LADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIA 2144 Query 2374 VLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASL 2433 VLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASL Sbjct 2145 VLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASL 2204 Query 2434 GALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPH 2493 GALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPH Sbjct 2205 GALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPH 2264 Query 2494 VSAPTIINYVTNLQLLGLL 2512 VSAPTIINYVTNLQLLGLL Sbjct 2265 VSAPTIINYVTNLQLLGLL 2283 >gi|308373889|ref|ZP_07667680.1| peptide synthetase nrp [Mycobacterium tuberculosis SUMu006] gi|308343813|gb|EFP32664.1| peptide synthetase nrp [Mycobacterium tuberculosis SUMu006] Length=2092 Score = 4181 bits (10844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 2092/2092 (100%), Positives = 2092/2092 (100%), Gaps = 0/2092 (0%) Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 1 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 60 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 61 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 120 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 121 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 180 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 181 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 240 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 241 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 300 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 301 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 360 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 361 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 420 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 421 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 480 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 481 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 540 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 541 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 600 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 601 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 660 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 661 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 720 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 721 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 780 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 781 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 840 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 841 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 900 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 901 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 960 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 961 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1020 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1021 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1080 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1081 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1140 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1141 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1200 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1201 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1260 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1261 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1320 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA Sbjct 1321 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1380 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL Sbjct 1381 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1440 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG Sbjct 1441 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1500 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN Sbjct 1501 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1560 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR Sbjct 1561 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 1620 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL Sbjct 1621 ALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 1680 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 2160 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG Sbjct 1681 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSG 1740 Query 2161 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 2220 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL Sbjct 1741 DPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHEL 1800 Query 2221 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 2280 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA Sbjct 1801 FGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWA 1860 Query 2281 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 2340 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG Sbjct 1861 GGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATG 1920 Query 2341 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 2400 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI Sbjct 1921 IAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGI 1980 Query 2401 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2460 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL Sbjct 1981 GLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPL 2040 Query 2461 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 2041 KPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2092 >gi|289441470|ref|ZP_06431214.1| peptide synthetase nrp [Mycobacterium tuberculosis T46] gi|289414389|gb|EFD11629.1| peptide synthetase nrp [Mycobacterium tuberculosis T46] Length=1843 Score = 3473 bits (9005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1775/1799 (99%), Positives = 1780/1799 (99%), Gaps = 1/1799 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 9 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 68 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 69 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 128 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 129 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 188 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 189 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 248 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 249 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 308 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 309 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 368 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 369 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 428 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 429 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 488 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 489 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 548 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 549 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 608 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 609 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 668 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRC A + + S + Sbjct 669 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCGAGARRC-TRRSHADN 727 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 ++ TVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 728 WPTARRWCSPTVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 787 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 840 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR Sbjct 788 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTR 847 Query 841 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 900 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP Sbjct 848 RIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVP 907 Query 901 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 960 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG Sbjct 908 NIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEG 967 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP Sbjct 968 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1027 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF Sbjct 1028 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1087 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR Sbjct 1088 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1147 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE Sbjct 1148 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1207 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ Sbjct 1208 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1267 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL Sbjct 1268 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1327 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Sbjct 1328 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1387 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID Sbjct 1388 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1447 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA Sbjct 1448 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1507 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV Sbjct 1508 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1567 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1620 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY Sbjct 1568 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAY 1627 Query 1621 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG Sbjct 1628 PGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1687 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE Sbjct 1688 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1747 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSG 1799 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSG Sbjct 1748 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSG 1806 Score = 77.8 bits (190), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 149/559 (27%), Positives = 217/559 (39%), Gaps = 56/559 (10%) Query 1538 GAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFML---GDAVPVAAV 1594 GA PG+ + + + ++A G Y D A+ + GD + V V Sbjct 487 GAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVV 546 Query 1595 TTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHR 1654 A + + GHD + VVD + A AYI+ TSGTTG+PK V I+H Sbjct 547 DVAATQLAVVGHD-ELRKVVDERVTQVTHDALL--ATKTAYIMPTSGTTGQPKLVRISHG 603 Query 1655 NVTRLFASLPARLSAAQVWS------QCHSYGFDASAWEIWGALLGGGRLVIVPESVAAS 1708 + A +S A W QC D S EI+G G RLV S A Sbjct 604 S----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAMK 656 Query 1709 PNDFHGL---LVAEHVSVLTQTPAAVAMLPTQG--LESVA------LVVAGEACPAALVD 1757 D L LVA +++ A +L G ++++ +V+ GEA Sbjct 657 TGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCGAGA 716 Query 1758 RWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVS-GAALFVLDSWLRPVPAGV 1816 R R + + PT C+ P + +P + + AL L + P + Sbjct 717 RRCTRRSHADNW-PTARRWCS----PTVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL 771 Query 1817 A-GELYIAGAGVGVGYWRRAGLTASRF-VACPFGGSGARMYRTGDLVCWRADGQLEFLGR 1874 A GE+ I G V GY G+ F GS R + TGD V A+G F GR Sbjct 772 AFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGR 828 Query 1875 TDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAG 1934 D VKI G R+++ EV +AE V +A E G + + G D A Sbjct 829 KDAVVKISGKRVDIAEVTRRIAEDPAVSD---VAVELHSGSLGVWFKSQRTREGEQDAAA 885 Query 1935 LRAQLAQRLPGYLVPAA-----VVVIDALPLTVNGKLDHRALP-APEYGDTNGYRAPAGP 1988 A R+ LV VV + +P NGK+D LP P++ A G Sbjct 886 -----ATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ 940 Query 1989 VEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASST 2048 ++ I++R LG +G D S G SL +R++ L L + L+ A + Sbjct 941 RAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTA 999 Query 2049 RGLSQLLGRDARPTSDPRL 2067 L+ PT + R Sbjct 1000 ANLADYAPTPDAPTGEDRF 1018 >gi|339293168|gb|AEJ45279.1| peptide synthetase nrp [Mycobacterium tuberculosis CCDC5079] Length=1622 Score = 3219 bits (8345), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1621/1622 (99%), Positives = 1622/1622 (100%), Gaps = 0/1622 (0%) Query 891 VSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAI 950 +SSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAI Sbjct 1 MSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAI 60 Query 951 GPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDR 1010 GPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDR Sbjct 61 GPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDR 120 Query 1011 FRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVV 1070 FRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVV Sbjct 121 FRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVV 180 Query 1071 GRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLAT 1130 GRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLAT Sbjct 181 GRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLAT 240 Query 1131 EIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQ 1190 EIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQ Sbjct 241 EIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQ 300 Query 1191 YVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLV 1250 YVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLV Sbjct 301 YVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLV 360 Query 1251 VDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNL 1310 VDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNL Sbjct 361 VDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNL 420 Query 1311 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL 1370 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL Sbjct 421 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL 480 Query 1371 IQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYR 1430 IQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYR Sbjct 481 IQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYR 540 Query 1431 TDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPT 1490 TDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPT Sbjct 541 TDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPT 600 Query 1491 PVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFE 1550 PVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFE Sbjct 601 PVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFE 660 Query 1551 RCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI 1610 RCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI Sbjct 661 RCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI 720 Query 1611 IDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA 1670 IDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA Sbjct 721 IDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA 780 Query 1671 QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAA 1730 QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAA Sbjct 781 QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAA 840 Query 1731 VAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGM 1790 VAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGM Sbjct 841 VAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGM 900 Query 1791 PPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGS 1850 PPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGS Sbjct 901 PPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGS 960 Query 1851 GARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIARE 1910 GARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIARE Sbjct 961 GARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIARE 1020 Query 1911 DRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRA 1970 DRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRA Sbjct 1021 DRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRA 1080 Query 1971 LPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAIN 2030 LPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAIN Sbjct 1081 LPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAIN 1140 Query 2031 TTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFID 2090 TTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFID Sbjct 1141 TTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFID 1200 Query 2091 ADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDAR 2150 ADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDAR Sbjct 1201 ADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDAR 1260 Query 2151 RRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAA 2210 RRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAA Sbjct 1261 RRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAA 1320 Query 2211 MVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVIS 2270 MVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVIS Sbjct 1321 MVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVIS 1380 Query 2271 PTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVT 2330 PTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVT Sbjct 1381 PTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVT 1440 Query 2331 RMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATY 2390 RMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATY Sbjct 1441 RMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATY 1500 Query 2391 HVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLL 2450 HVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLL Sbjct 1501 HVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLL 1560 Query 2451 ASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLG 2510 ASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLG Sbjct 1561 ASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLG 1620 Query 2511 LL 2512 LL Sbjct 1621 LL 1622 Score = 100 bits (248), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 146/512 (29%), Positives = 208/512 (41%), Gaps = 60/512 (11%) Query 530 GDGILVTVVDVAATQLAVVGHD-ELRKVVDERVTQVTHDALL--ATKTAYIMPTSGTTGQ 586 GD + V V A + + GHD + VVD + A AYI+ TSGTTG+ Sbjct 696 GDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGE 755 Query 587 PKLVRISHGS----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV 642 PK V I+H + A +S A W QC D S EI+G G RLV Sbjct 756 PKGVGITHRNVTRLFASLPARLSAAQVWS------QCHSYGFDASAWEIWGALLGGGRLV 809 Query 643 ---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGG 699 S A D L LVA +++ A +L G ++++ +V+ G Sbjct 810 IVPESVAASPNDFHGL---LVAEHVSVLTQTPAAVAMLPTQG--LESVA------LVVAG 858 Query 700 EAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM--------DGALL 751 EA + VD+W + G +L++YGPTE T+ A + + M AL Sbjct 859 EACPAALVDRW-----APGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALF 913 Query 752 RLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRV 808 L + P +A GE+ I G V GY G+ F GS R + TGD V Sbjct 914 VLDSWLRPVPAGVA-GELYIAGAGVGVGYWRRAGLTASRF-VACPFGGSGARMYRTGDLV 971 Query 809 TVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSD---VAVELHSGSLGVWFK 865 A+G F GR D VKI G R+++ EV +AE V +A E G + Sbjct 972 CWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGY 1031 Query 866 SQRTREGEQDAAA-----ATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQ 920 + G D A A R+ LV VV + +P NGK+D LP P+ Sbjct 1032 ATEIAPGAVDPAGLRAQLAQRLPGYLVPAA-----VVVIDALPLTVNGKLDHRALP-APE 1085 Query 921 WSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW 979 + A G ++ I++R LG +G D S G SL +R++ L Sbjct 1086 YGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNA 1145 Query 980 RLSLLDLIGADTAANLADYAPTPDAPTGEDRF 1011 L + L+ A + L+ PT + R Sbjct 1146 DLPVRALLHASSTRGLSQLLGRDARPTSDPRL 1177 >gi|289764217|ref|ZP_06523595.1| hypothetical protein TBIG_00526 [Mycobacterium tuberculosis GM 1503] gi|289711723|gb|EFD75739.1| hypothetical protein TBIG_00526 [Mycobacterium tuberculosis GM 1503] Length=1294 Score = 2498 bits (6475), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1265/1278 (99%), Positives = 1265/1278 (99%), Gaps = 5/1278 (0%) Query 289 FPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPG 348 FPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPG Sbjct 16 FPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPG 75 Query 349 LRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAAL 408 LRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAAL Sbjct 76 LRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAAL 135 Query 409 ESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFV 468 ESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFV Sbjct 136 ESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFV 195 Query 469 YPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITE 528 YPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITE Sbjct 196 YPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITE 255 Query 529 HGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPK 588 HGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPK Sbjct 256 HGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPK 315 Query 589 LVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMK 648 LVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMK Sbjct 316 LVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMK 375 Query 649 TGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVD 708 TGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVD Sbjct 376 TGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVD 435 Query 709 KWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGE 768 KWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGE Sbjct 436 KWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGE 495 Query 769 VVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKI 828 VVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKI Sbjct 496 VVIVGDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKI 555 Query 829 SGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVS 888 SGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVS Sbjct 556 SGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVS 615 Query 889 LGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGR 948 LGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGR Sbjct 616 LGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGR 675 Query 949 AIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE 1008 AIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE Sbjct 676 AIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE 735 Query 1009 DRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVAD 1068 DRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVAD Sbjct 736 DRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVAD 795 Query 1069 VVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDL 1128 VVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDL Sbjct 796 VVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDL 855 Query 1129 ATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLP 1188 ATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLP Sbjct 856 ATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLP 915 Query 1189 VQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGAS 1248 VQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGAS Sbjct 916 VQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGAS 975 Query 1249 LVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALD 1308 LVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALD Sbjct 976 LVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALD 1035 Query 1309 NLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHH 1368 NLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHH Sbjct 1036 NLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHH 1095 Query 1369 PLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVE 1428 PLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVE Sbjct 1096 PLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVE 1155 Query 1429 YRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPA 1488 YRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPA Sbjct 1156 YRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPA 1215 Query 1489 PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALL 1548 PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVA Sbjct 1216 PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVAQR 1275 Query 1549 FERCAPAVVAMVAVLKTG 1566 R V AVLK G Sbjct 1276 ARR-----VVRCAVLKRG 1288 Score = 101 bits (251), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 155/563 (28%), Positives = 225/563 (40%), Gaps = 63/563 (11%) Query 1538 GAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFML---GDAVPVAAV 1594 GA PG+ + + + ++A G Y D A+ + GD + V V Sbjct 206 GAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVV 265 Query 1595 TTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHR 1654 A + + GHD + VVD + A AYI+ TSGTTG+PK V I+H Sbjct 266 DVAATQLAVVGHD-ELRKVVDERVTQVTHDALL--ATKTAYIMPTSGTTGQPKLVRISHG 322 Query 1655 NVTRLFASLPARLSAAQVWS------QCHSYGFDASAWEIWGALLGGGRLVIVPESVAAS 1708 + A +S A W QC D S EI+G G RLV S A Sbjct 323 S----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAMK 375 Query 1709 PNDFHGL---LVAEHVSVLTQTPAAVAMLPTQG--LESVA------LVVAGEACPAALVD 1757 D L LVA +++ A +L G ++++ +V+ GEA + VD Sbjct 376 TGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVD 435 Query 1758 RW-----APGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 +W + G +L++YGPTE T+ A + + M AL L + P Sbjct 436 KWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM--------DGALLRLGRPILPN 487 Query 1813 PAGVA-GELYIAGAGVGVGYWRRAGLTASRF-VACPFGGSGARMYRTGDLVCWRADGQLE 1870 +A GE+ I G V GY G+ F GS R + TGD V A+G Sbjct 488 TVFLAFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPV 544 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 F GR D VKI G R+++ EV +AE V +A E G + + G Sbjct 545 FSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSD---VAVELHSGSLGVWFKSQRTREGEQ 601 Query 1931 DPAGLRAQLAQRLPGYLVPAA-----VVVIDALPLTVNGKLDHRALP-APEYGDTNGYRA 1984 D A A R+ LV VV + +P NGK+D LP P++ A Sbjct 602 DAAA-----ATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTA 656 Query 1985 PAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLH 2044 G ++ I++R LG +G D S G SL +R++ L L + L+ Sbjct 657 ETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIG 715 Query 2045 ASSTRGLSQLLGRDARPTSDPRL 2067 A + L+ PT + R Sbjct 716 ADTAANLADYAPTPDAPTGEDRF 738 >gi|296164404|ref|ZP_06846979.1| syringomycin synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900244|gb|EFG79675.1| syringomycin synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=8230 Score = 2109 bits (5464), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1167/1967 (60%), Positives = 1379/1967 (71%), Gaps = 57/1967 (2%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AYI+ TSGTTG PK V ++H ++A D++ G T QC L D SV EIFG Sbjct 6290 AYIIYTSGTTGIPKGVAVTHRNVAQLLDSLDDELELGQVWT--QCHSLAFDFSVWEIFGA 6347 Query 635 AACGARLVRSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRSRLR 693 G RLV + L LV + +++ P+A L AD A D + +L+ Sbjct 6348 LLRGGRLVVVSDAVVRSPEELYALLVREQVSVLSQTPSAFDALQTADALAPDLAQQLKLQ 6407 Query 694 QIVIGGEAIRCSAVDKWLESAASQGI-SLLSSYGPTEATVVATFLPIVC-----DQTTMD 747 +V GGEA+ + +WL++ G+ L++ YG TE TV A+F + D + + Sbjct 6408 TLVFGGEALEARRLGRWLDN--HPGLPRLINMYGTTETTVHASFRELGAGDVGGDASPIG 6465 Query 748 GALLRLG--------RPILPNTVFLAFGEVVIVGDLVADGYLGIDG-DGFGTVTAADGS- 797 G L L RP+ V GE+ + G +A GY+G G G V G Sbjct 6466 GPLAHLAFFVLDRWLRPVPAGVV----GELFVAGRGLACGYVGRSGLTGSRFVACPSGPP 6521 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 +R + TGD V A+G + GR D VKI G R+++ E+ + V AV Sbjct 6522 GQRMYRTGDLVRWGADGQLRYLGRADDQVKIRGHRIELGEIHTVLTGLAGVKRAAVIARE 6581 Query 858 GSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD 913 G V + + AA A R+ +V V V V IP NGK+D+ Sbjct 6582 DRPGDKRLVGYVTGSADPAAIRAALAERLPAYMVPSAV-----VVVDAIPLTVNGKLDTR 6636 Query 914 NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPE 972 LP P + A A L+ I++R LG +G D S G SL +R++ Sbjct 6637 ALP-APDYRGAAPYRAPATATEEILAGIYARVLGIDRVGVDDSFFDLGGDSLAAMRLIAA 6695 Query 973 TRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRL 1032 L L + L A T LA P A G R PLVA +RPA IPLSFAQ RL Sbjct 6696 VNAGLNAHLGVRSLFEAPTIHLLA---PRLGA-DGAGR-TPLVAIERPAVIPLSFAQSRL 6750 Query 1033 WFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVI 1092 WFLDQLQ P+ VYNMA ALRLRG LD ALGAA+ DVV RHESLRTVF A +G P+Q+V+ Sbjct 6751 WFLDQLQGPSAVYNMAAALRLRGSLDVGALGAALGDVVARHESLRTVFVAAEGTPQQIVV 6810 Query 1093 EARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVA 1152 AD+ D+VDATAWP RL A+E A ++FDL TEIPLR WLFR A DEHVLV+V Sbjct 6811 PPAEADVAYDVVDATAWPPGRLAEAVEAVAHYAFDLGTEIPLRAWLFRTAGDEHVLVSVL 6870 Query 1153 HHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPI 1212 HHIAADG S+ PL DL AYA RCAG P WAPL VQY DYTLWQR+ GDLDD DSPI Sbjct 6871 HHIAADGLSLTPLVRDLGVAYARRCAGEPPGWAPLAVQYADYTLWQRDQFGDLDDPDSPI 6930 Query 1213 AAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATS 1272 A QL +WE+ LAGMPERL LPT RPYP VAD RGA++ V WPA +QQ+VR +AR HNATS Sbjct 6931 AGQLRFWEHNLAGMPERLVLPTDRPYPLVADHRGATVSVQWPAELQQRVREVARAHNATS 6990 Query 1273 FMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAE 1332 FMVV A LAVLLS LSGS +VAVGFPIAGR DP LD++VGFFVNTLVLR +L GDP+ A+ Sbjct 6991 FMVVQAALAVLLSTLSGSSEVAVGFPIAGRRDPVLDDVVGFFVNTLVLRTDLGGDPTVAQ 7050 Query 1333 LLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQA 1392 +L QVR RSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ N L LGDL Sbjct 7051 VLAQVRGRSLAAYEHQDVPFEVLVERLHPARSLGHHPLVQVMLAWQGNDATDLRLGDLDV 7110 Query 1393 TPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVA 1452 TP+P+DT TARMDL FSLAE + G EPAGIGG VE+RTDVF+A I+ L++RL +VLVA Sbjct 7111 TPLPVDTHTARMDLTFSLAEHWGAGGEPAGIGGQVEFRTDVFDAGTIETLVKRLHRVLVA 7170 Query 1453 VAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVC 1512 + A +R +SSID LD ERARLDEWGNRA + P P SI AQV P+A A+C Sbjct 7171 ITADADRPLSSIDLLDDGERARLDEWGNRAACSRPVTCP-SIVAAFTAQVDLAPKAPALC 7229 Query 1513 CGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPI 1572 CGD +MTYRELD A+NRLAH L GAGPGECV LL ER A AVVA++AVLKTGAAYLPI Sbjct 7230 CGDRTMTYRELDRAANRLAHLLIDQGAGPGECVGLLAERSAEAVVAILAVLKTGAAYLPI 7289 Query 1573 DPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDAL--AAYPGTPPPMPAA 1630 DP PP R+ F+L DA P+AAVTTAGLRSRL G+DL ++DV D G P P A Sbjct 7290 DPGLPPARIEFLLTDAAPIAAVTTAGLRSRLDGYDLAVVDVDDPALDTRPDGAPAAAPTA 7349 Query 1631 VNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 ++AY++YTSGTTG PKGV +THRNVT+LFA L A L A WS HS FD S WEI+G Sbjct 7350 DDVAYLIYTSGTTGTPKGVAVTHRNVTQLFAPLDAPLPVAGAWSHSHSLVFDVSVWEIFG 7409 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 ALL GGR+++VP++ A SP + H LL AE VSVLTQTP+ MLP +GL+S ALVVAGEA Sbjct 7410 ALLHGGRVLVVPDATARSPRELHALLSAERVSVLTQTPSEAGMLPVEGLDSAALVVAGEA 7469 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CP +VDRWAPGR MLN YGPTETT+C A+SAPL P S PPIG PV GAALFVLD WLR Sbjct 7470 CPEEVVDRWAPGRTMLNVYGPTETTMCVAVSAPLAPESRTPPIGAPVPGAALFVLDGWLR 7529 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 P GV GELY+AGAGV GY RR+GLTASRFVACPFG GARMYRTGDL CW DGQL+ Sbjct 7530 PAATGVVGELYVAGAGVTYGYVRRSGLTASRFVACPFGAPGARMYRTGDLACWGPDGQLQ 7589 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 +LGR DDQVKIRG+RIELGE+ TAL L GV QA V+AREDRPGDKRLVGY T G Sbjct 7590 YLGRADDQVKIRGHRIELGEIRTALTGLGGVEQAAVVAREDRPGDKRLVGYVT----GTA 7645 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 D A LR LA RLP Y+VPAAVVV+DALPLTVNGKLD RALPAP Y D +GYR PA PVE Sbjct 7646 DAAALRVALADRLPAYMVPAAVVVLDALPLTVNGKLDTRALPAPAYTDGDGYRPPATPVE 7705 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 +T+A I+A+VLG+ERVGV +SFF+LGGDSL+AMR++AAI +TL LPVRA+ A S R Sbjct 7706 ETLADIYAQVLGMERVGVQESFFDLGGDSLSAMRLVAAIQSTLGVHLPVRAVFDAPSVRN 7765 Query 2051 LSQLLGRDARPTSDP---RLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPEL 2107 L+Q L R A + P SVHG + TEV+ASDLTLD+F+DA TL A LPGP ++ Sbjct 7766 LAQQLDRHAEEAAQPGRATFASVHGRDATEVYASDLTLDKFVDAATLGNAPALPGPGAQV 7825 Query 2108 RTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDEDARRRLEKTFDSGDPELLR 2166 RTVLLTGATGFLGRYL L+ L +L+ VDG LICLVRA SDE+ARRRLE TFDSGDP LL Sbjct 7826 RTVLLTGATGFLGRYLALQWLEQLELVDGTLICLVRAGSDEEARRRLETTFDSGDPRLLA 7885 Query 2167 HFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA-FPYHELFGPNV 2225 HF LAA LEV+AGDK +LGLD+ W+RLA+TVDLIVD AA+VN PY ELFGPNV Sbjct 7886 HFAGLAAHHLEVLAGDKGATNLGLDERTWQRLADTVDLIVDCAAVVNGVLPYRELFGPNV 7945 Query 2226 AGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGT 2285 AGTAELIR+ALTT+LKP+T+VSTA+VG ++ +AFTEDADIR ISPTR +DGG++ GYG Sbjct 7946 AGTAELIRLALTTRLKPYTFVSTANVGDGVDRAAFTEDADIRAISPTRIIDGGYSNGYGN 8005 Query 2286 SKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRS 2345 SKWAGEVLLREA+DLC LPV VFRC MILADTSYAGQLN+SD TRMVLS+ ATG+APRS Sbjct 8006 SKWAGEVLLREAHDLCGLPVTVFRCDMILADTSYAGQLNLSDMFTRMVLSIAATGVAPRS 8065 Query 2346 FYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEY 2405 FY D+EGNRQR+HFD LPV FVAEA+ LGA+ ++AGF TYHVMNPHDDGIG+DEY Sbjct 8066 FYRLDAEGNRQRSHFDALPVEFVAEAVTALGAK----AVAGFGTYHVMNPHDDGIGIDEY 8121 Query 2406 VDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRG 2465 VDWLIEAGYPI RIDDF EWL+RFEA+L LP+RQR+HSVLP+L ++++++P P RG Sbjct 8122 VDWLIEAGYPIERIDDFGEWLRRFEAALRELPERQRQHSVLPLLQLPSTRQVEPGAPARG 8181 Query 2466 CSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 A TDRFRAAVR AK+G D D+PDIP VS P I+ YVT+LQLLGLL Sbjct 8182 ALASTDRFRAAVREAKIGPDGDDPDIPRVSPPVIVKYVTDLQLLGLL 8228 Score = 1419 bits (3673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 841/1626 (52%), Positives = 1034/1626 (64%), Gaps = 101/1626 (6%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYS--------------VCDTADEIS 520 L++ GA PG+ + + + + + ++A G Y + D A + Sbjct 1552 LIEYGAGPGECVALLAERSAQAVAAMLAVLKTGAAYLPIDPGLPAARIEFLLGDAAPIAA 1611 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 + T + DG +T +DV +A D L E V AY++ T Sbjct 1612 IVTPGMRSRLDGSDLTALDVDDPAVATQSTDGLSPPDAENV-------------AYVIYT 1658 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V ++H ++ +++ R + G QC L D SV EIFG GAR Sbjct 1659 SGTTGVPKGVAVTHHNVTQLLESVDREFELG--RVWSQCHSLAFDFSVWEIFGALLRGAR 1716 Query 641 LVRSAAMKTGDLAALVDDLVA-----RETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQI 695 LV + D+ +DL A R + + P+A + L + +L+ + Sbjct 1717 LV----IVPDDVVRSPEDLHAMLVRERVSVLSQTPSAFYALSPEPSEL-------KLQTV 1765 Query 696 VIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPI----VCDQTTMDGA-L 750 V GGEA+ + +WL + L++ YG TE TV A+F I V D T+ GA L Sbjct 1766 VFGGEALEPPRLGRWLHNRPKLP-RLINMYGITETTVHASFREITEADVGDTTSPIGAPL 1824 Query 751 LRLGRPILPNTVFLA----FGEVVIV-----------GDLVADGYLGIDGDGFGTVTAAD 795 LG +L + GE+ + L A ++ FG+ Sbjct 1825 AHLGFFVLDEWLHPVPAGVTGELYVAGGGVACGYGGRAGLTASRFVACPFGAFGS----- 1879 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL 855 R + TGD V A+G + GR D VKI G R+++ E+ + V AV Sbjct 1880 ----RMYRTGDLVRWGADGRLQYLGRADEQVKIRGYRIELGEIRAALTAFDEVEQAAVVA 1935 Query 856 HSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID 911 G V + + A A R+ +V V + IP NGK+D Sbjct 1936 REDRPGDKRLVAYVTGTADPAHVRARLADRLPGYMVPAAVVAVD-----AIPLTLNGKLD 1990 Query 912 SDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRIL 970 + LP P + G A L+ I++R LG +G + S G SL +R++ Sbjct 1991 TRALP-APDYQEGGEYRAPATPVEEILAGIYARVLGLERVGVEESFFDLGGDSLSAMRLV 2049 Query 971 PETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQR 1030 L RL + L A T LA P G R +VA RPA +PLSFAQ Sbjct 2050 AAAATGLDARLEVRTLFEAPTIRQLA-----PRLGAGGGRAARVVAGARPAVVPLSFAQS 2104 Query 1031 RLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQL 1090 RLWF QLQ P+PVYNMA A+RL G +D EAL AA+ DVV RHESLRTVF A G P+Q+ Sbjct 2105 RLWFTGQLQGPSPVYNMAAAMRLDGRVDVEALRAALGDVVARHESLRTVFMARKGTPQQV 2164 Query 1091 VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVA 1150 V+ A RAD G +VDA WPA RL AIE AA H FDLA E+PLR LFR+ + HVLVA Sbjct 2165 VVPAERADFGWRVVDALGWPASRLDEAIEAAAHHPFDLANEVPLRAKLFRVDANRHVLVA 2224 Query 1151 VAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDS 1210 VAHHIAADG S+ PL ADL AYASRCAG AP WAPLPVQY+DYTLWQ+ LGDLDD S Sbjct 2225 VAHHIAADGSSLKPLVADLGLAYASRCAGHAPPWAPLPVQYIDYTLWQQARLGDLDDPGS 2284 Query 1211 PIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNA 1270 PIA QL YW++ALAG+PERL LPT RPYP VAD RGAS+ VDWPA VQQ+VR AR HNA Sbjct 2285 PIAGQLRYWQHALAGLPERLALPTDRPYPAVADHRGASVSVDWPAEVQQRVREAARAHNA 2344 Query 1271 TSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSF 1330 TSFMV+ AGLAVLL+K+S + DVAVGFPIAGR DPALD LVGFFVNTLVLRV+LAG+P+ Sbjct 2345 TSFMVIQAGLAVLLAKVSATSDVAVGFPIAGRPDPALDELVGFFVNTLVLRVDLAGNPTL 2404 Query 1331 AELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDL 1390 AE+L QVR RSLAAYE+QDVPFE LV+RL P+R+L HHPL+QVML WQ+N +L+LG+L Sbjct 2405 AEVLAQVRQRSLAAYEHQDVPFEALVERLNPSRSLAHHPLVQVMLTWQNNGPAELSLGEL 2464 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 Q TP+P+ TRTARMDLVFSLAER+++G +PAGIGGAVE+RTDVF+A I LI+RLR+VL Sbjct 2465 QVTPLPVSTRTARMDLVFSLAERWTDGGQPAGIGGAVEFRTDVFDADTITTLIDRLRRVL 2524 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 A+ P R +S+ DALD E L+E GNRAVL A + PVSIP + AAQ R P+A A Sbjct 2525 DAMTTDPGRPLSATDALDAAEHRLLEEMGNRAVL-ARSWVPVSIPGLFAAQATRTPDAVA 2583 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 V C AS+TY EL+E++NRLAH L GAG G VA++ R A+VA++AVLKTGAAYL Sbjct 2584 VSCAGASLTYGELEESANRLAHVLIERGAGRGASVAVVLSRSTEAIVAILAVLKTGAAYL 2643 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGT-PPPMP 1628 PIDPA P R+ FML D PVAAV+TA L +LAG+ LP++DV ALA P T P P P Sbjct 2644 PIDPALPAARIEFMLSDTAPVAAVSTAALAEKLAGYVLPMVDVHSPALAGQPATAPAPGP 2703 Query 1629 AAVNLAYILYTSGTTGEPKGVGITHRNVTRLF--ASLPARLSAAQVWSQCHSYGFDASAW 1686 ++A+I+YTSGTTG PKGV ++H NVTRLF + L + QVWSQ HSY FD S W Sbjct 2704 EPEDVAHIIYTSGTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWSQFHSYAFDFSVW 2763 Query 1687 EIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVV 1746 EIWGALL GGRLV+VPE+VA SP DFH LLVAE V+VL+QTPAAV ML QGLE ALV+ Sbjct 2764 EIWGALLHGGRLVVVPEAVARSPKDFHALLVAEGVTVLSQTPAAVRMLSPQGLEGTALVI 2823 Query 1747 AGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLD 1806 E PA +VDRWAPGRVM+N YGPTETTI A SA L G PPIG V GAALFVLD Sbjct 2824 GAEPVPAEVVDRWAPGRVMVNVYGPTETTIFATASAALVAKGGAPPIGSAVPGAALFVLD 2883 Query 1807 SWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD 1866 WLRP P GV GELY+AG GVG+GY RRAGLT SRFVACPFG GARMYRTGDLVCW AD Sbjct 2884 GWLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGARMYRTGDLVCWGAD 2943 Query 1867 GQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIA 1926 GQL ++GR D QVKIRGYRIE+GE+ +ALA L GV QAVV+ REDRPGDKRLVGY T Sbjct 2944 GQLRYVGRADAQVKIRGYRIEIGEIQSALAALDGVEQAVVVVREDRPGDKRLVGYLT--- 3000 Query 1927 PGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPA 1986 G +PA LR LA+RLPGY+VPAA+V + LP+TVNGKLD RALPAPEY +GYRAP+ Sbjct 3001 -GTAEPAALRTALAERLPGYMVPAALVALPELPMTVNGKLDTRALPAPEY-HASGYRAPS 3058 Query 1987 GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHAS 2046 P E+ +AGI+A+VLG++RVG+D SFF+LGGDSL+AMR +AAIN+ L+ L VRAL A Sbjct 3059 TPTEEILAGIYAQVLGVDRVGIDQSFFDLGGDSLSAMRAVAAINSGLDRALSVRALFEAP 3118 Query 2047 STRGLS 2052 + L+ Sbjct 3119 TVAQLA 3124 Score = 1408 bits (3645), Expect = 0.0, Method: Compositional matrix adjust. Identities = 843/1591 (53%), Positives = 1013/1591 (64%), Gaps = 84/1591 (5%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEIS 520 L++RGA G + + + I ++A G Y + DTA + Sbjct 2607 LIERGAGRGASVAVVLSRSTEAIVAILAVLKTGAAYLPIDPALPAARIEFMLSDTAPVAA 2666 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 V T A+ E G ++ +VDV + LA G V H I+ T Sbjct 2667 VSTAALAEKLAGYVLPMVDVHSPALA--GQPATAPAPGPEPEDVAH----------IIYT 2714 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V +SH ++ DA G+ Q D SV EI+G G R Sbjct 2715 SGTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWSQFHSYAFDFSVWEIWGALLHGGR 2774 Query 641 LV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVI 697 LV + A D AL LVA T++ A ++L G A+ VI Sbjct 2775 LVVVPEAVARSPKDFHAL---LVAEGVTVLSQTPAAVRMLSPQGLEGTAL--------VI 2823 Query 698 GGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQ-------TTMDGAL 750 G E + VD+W + G +++ YGPTE T+ AT + + + + GA Sbjct 2824 GAEPVPAEVVDRW-----APGRVMVNVYGPTETTIFATASAALVAKGGAPPIGSAVPGAA 2878 Query 751 LRLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF-GTVTAADGSRRRAFATGD 806 L + L T GE+ + G V GY+ G+ G F A G+R + TGD Sbjct 2879 LFVLDGWLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGAR--MYRTGD 2936 Query 807 RVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----V 862 V A+G + GR DA VKI G R++I E+ +A V V + G V Sbjct 2937 LVCWGADGQLRYVGRADAQVKIRGYRIEIGEIQSALAALDGVEQAVVVVREDRPGDKRLV 2996 Query 863 WFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWS 922 + + A A R+ +V + V +P +P NGK+D+ LP P++ Sbjct 2997 GYLTGTAEPAALRTALAERLPGYMVPAAL-----VALPELPMTVNGKLDTRALP-APEYH 3050 Query 923 AAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRL 981 A+G T L+ I+++ LG +G D S G SL +R + L L Sbjct 3051 ASGYRAPSTPTEEI-LAGIYAQVLGVDRVGIDQSFFDLGGDSLSAMRAVAAINSGLDRAL 3109 Query 982 SLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRP 1041 S+ L A T A LA P LVA +RP +PLSFAQ RLWF+DQL P Sbjct 3110 SVRALFEAPTVAQLA-----PRIGGSGGGLAALVAGERPVVVPLSFAQSRLWFIDQLNGP 3164 Query 1042 APVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGC 1101 +PVYNMA ALRLRG LDT AL AA+ADVV RHESLRTVF A DG P+Q+V+ RA + Sbjct 3165 SPVYNMAAALRLRGRLDTAALRAALADVVARHESLRTVFAAPDGTPQQVVLPPARASVRW 3224 Query 1102 DIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWS 1161 D+V W + RL+ AIE AA + FDLA EIPLR LFR+ EHVLVAVAHHIAADGWS Sbjct 3225 DVVKTDGWSSSRLEEAIEAAASYPFDLAAEIPLRATLFRVGAGEHVLVAVAHHIAADGWS 3284 Query 1162 VAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWEN 1221 + PL ADL AYASRCAG AP WA LPVQYVDYTLWQR GDLDD S IAAQLAYW++ Sbjct 3285 LRPLAADLGVAYASRCAGEAPGWAELPVQYVDYTLWQRAQFGDLDDPHSAIAAQLAYWQD 3344 Query 1222 ALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLA 1281 ALAGMPERL LPT RPYPPVAD RGA + V+WP +Q VR +A +HNATSFMVV A LA Sbjct 3345 ALAGMPERLELPTDRPYPPVADYRGARVAVEWPPELQVLVRELAGEHNATSFMVVQAALA 3404 Query 1282 VLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARS 1341 VLLSK+ + DVAVGFPIAGR DPALD+LVGFFVNTLVLR +L G+P+ AELL QV+ RS Sbjct 3405 VLLSKVGATSDVAVGFPIAGRRDPALDDLVGFFVNTLVLRTDLGGNPTVAELLAQVQQRS 3464 Query 1342 LAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRT 1401 LAAYE+QDVPFEVLV+RL PTR+LTHHPLIQV+LAWQ+ LNLGDL+ TP+P +TR+ Sbjct 3465 LAAYEHQDVPFEVLVERLHPTRSLTHHPLIQVVLAWQNVEFADLNLGDLEVTPLPTETRS 3524 Query 1402 ARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTV 1461 ARMDLVFSLAER++E PAGIGGAVE+RTDVF+ I+ LIERL VLVA+ A P R V Sbjct 3525 ARMDLVFSLAERWTEDGRPAGIGGAVEFRTDVFDTARIEALIERLHHVLVAITADPSRRV 3584 Query 1462 SSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYR 1521 SSID LD E ARL GNRAVL P+ VSIP++ AAQV R P+A A+ C S TY Sbjct 3585 SSIDVLDEAEHARLAVVGNRAVLHGPSRAGVSIPELFAAQVDRAPDAVAITCAQRSWTYG 3644 Query 1522 ELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRV 1581 ELDEASNRLAH L GAGPGECVALL ER A AV AM+AVLKTGAAYLPIDP P R+ Sbjct 3645 ELDEASNRLAHLLIEYGAGPGECVALLAERSAQAVAAMLAVLKTGAAYLPIDPGLPTARI 3704 Query 1582 AFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTS 1640 FML DA+P+AAVTTAG+RSRL G DL ++D D LA PG PPP P A N+AY++YTS Sbjct 3705 EFMLADAIPIAAVTTAGVRSRLDGSDLAVLDFDDPELATQPGGPPPPPDAENVAYVIYTS 3764 Query 1641 GTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVI 1700 GTTG PKGV +TH NVT+L S+ L +VWSQCHS FD S WEI+GALL G RLVI Sbjct 3765 GTTGVPKGVAVTHHNVTQLLESVDRELELGRVWSQCHSLAFDFSVWEIFGALLRGARLVI 3824 Query 1701 VPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVA-LVVAGEACPAALVDRW 1759 VP+ V SP D H +LV E V+VL+ TP+AVA L QGL+SVA LV+ GE CP +VDRW Sbjct 3825 VPDDVVRSPEDLHAMLVRERVTVLSYTPSAVAGLAPQGLDSVATLVMGGEPCPPEVVDRW 3884 Query 1760 APGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGE 1819 APGRVM+N YGPTETT+ AA++APL G+G PPIG PV GAALFVLD WLRPVP GV GE Sbjct 3885 APGRVMVNQYGPTETTMYAAMTAPLTAGAGTPPIGSPVPGAALFVLDRWLRPVPEGVVGE 3944 Query 1820 LYIAGAGVGVGYWRRAGLTASRFVACPFGG---SGARMYRTGDLVCWRADGQLEFLGRTD 1876 LY+AG GV GY R GLTASRFVACPFGG G RMYRTGDL W +DGQL +LGR D Sbjct 3945 LYVAGRGVARGYPGRPGLTASRFVACPFGGPDAPGQRMYRTGDLARWDSDGQLHYLGRMD 4004 Query 1877 DQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLR 1936 DQVKIRGYRIELGE+ AL L GVGQAVVI REDRPG KRLV Y T G DPA LR Sbjct 4005 DQVKIRGYRIELGEIRAALTGLRGVGQAVVIVREDRPGYKRLVAYVT----GTADPAHLR 4060 Query 1937 AQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGI 1996 +LA RLP Y+VPAA+V +D +PLT+NGKLD RALPAP++ YRAP VE+ +AGI Sbjct 4061 GRLADRLPNYMVPAAIVALDDIPLTLNGKLDIRALPAPDFESAEHYRAPGDAVEEILAGI 4120 Query 1997 FARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 4121 YAQVLGVERVGVDDSFFDLGGDSILSMQVVA 4151 Score = 1344 bits (3478), Expect = 0.0, Method: Compositional matrix adjust. Identities = 839/1720 (49%), Positives = 1045/1720 (61%), Gaps = 115/1720 (6%) Query 402 ERIAAALESMAAMWDRPIAMI----VNDWFGIGPDGTRCQGDWPARQPSTPAWF-LDSAR 456 ER LE+MAA RP++ I ++ +G G R P S P F + AR Sbjct 5058 ERFRRVLEAMAADPARPLSTIDALDESEHVHLGAWGNRAVLTEPVTGASIPEAFAVQVAR 5117 Query 457 G----VHQFLGR-----------RRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLI 501 +F GR R + L +RGA PG + + I ++ Sbjct 5118 SPDAVALRFEGRSLTYRELDEAANRLAH----LLAERGAGPGTFVALLFSRSADAIVAML 5173 Query 502 ACHLAGCGY--------------SVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAV 547 A +G Y + D + +++ T + DG +TV+DV + Sbjct 5174 AVLKSGAAYLPIDPGLPDARIRFMIADASPIVALTTAELRPRLDGSALTVIDVHDPSVTA 5233 Query 548 VGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRA 607 E + AY++ TSGTTG PK V ++H ++ ++ Sbjct 5234 RPATAPPAPAPEDI-------------AYLIYTSGTTGAPKGVAVTHHNVTQLMASLHAP 5280 Query 608 YGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAMKTGDLAALVDDLVARET 664 A QC D+SV+EIFG G RLV DL AL+ + R + Sbjct 5281 LP--AAGVWSQCHSPAFDVSVQEIFGALLDGGRLVVVPEPVVHSPEDLRALL--IRERVS 5336 Query 665 TIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSS 724 + P+ L + +DA+ +VIGGE VD+W + G ++++ Sbjct 5337 VLSQTPSEAGAL---SPEGLDAVA------LVIGGEPCPDELVDRW-----APGRVMVNA 5382 Query 725 YGPTEATV-VATFLPIVCDQTTMDG------ALLRLGRPILPNTVFLAFGEVVIVGDLVA 777 YGPTE TV A P+ G ALL L + + P + GE+ + G VA Sbjct 5383 YGPTETTVDAAISAPLTAGAGAPIGSPVSGAALLVLDKWLRPVPAGV-VGELYVAGRGVA 5441 Query 778 DGYLGIDGDGFGTVTAA--DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDI 835 GYLG G A G R + TGD V +G + GR D VKI G RV++ Sbjct 5442 CGYLGRSGLTASRFIACPFGGPGARMYRTGDLVRWGTDGQLRYVGRADDQVKIRGHRVEL 5501 Query 836 AEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFF 895 E+ + V AV G L + G + AA A R+ +V + Sbjct 5502 GEIHTALTALAGVERAAVIARDGRLVGYITGTADPAGAR-AALAERLPAYMVPAAI---- 5556 Query 896 VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRA-IGPDS 954 V V IP NGK+D+ LP P++ A A L++I++R LG A +G D Sbjct 5557 -VEVDAIPLTVNGKLDARALP-APEYHDADAYRAPANPIEGILAEIYARILGLARVGVDE 5614 Query 955 SLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPL 1014 S G SL +R+ L +LS+ ++ A T LA P G D + Sbjct 5615 SFFDLGGDSLAAMRLAAAVNAGLDAQLSVRTVLEAPTVRRLA-----PLLGAGGDGPARV 5669 Query 1015 VAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHE 1074 VA RPA +PLSFAQ RLWF+DQL P+PVYNMA ALRLRG+L +AL AA+ DV+ RHE Sbjct 5670 VAGPRPAVLPLSFAQSRLWFIDQLHGPSPVYNMAAALRLRGHLAVDALAAALTDVLARHE 5729 Query 1075 SLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 +LRTVF AV+G PRQ+V+ RA G D+VDA WPA+RL+ A+E AA FDL+ E+PL Sbjct 5730 TLRTVFVAVEGTPRQVVVPPERAAAGWDVVDAAGWPAERLREAVEAAAADPFDLSAEMPL 5789 Query 1135 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDY 1194 R LFR+A+DEH+LVAV HHIAADGWS+ PL DL AYA RCAGRAP WAPL VQY DY Sbjct 5790 RARLFRVAEDEHLLVAVLHHIAADGWSLTPLVRDLGVAYAGRCAGRAPSWAPLAVQYADY 5849 Query 1195 TLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP 1254 TLWQRE LGDLDD DSPIA QL YW +AL GMPERL LPT RPYP VAD RGA+L V+WP Sbjct 5850 TLWQREQLGDLDDPDSPIAGQLRYWRDALDGMPERLELPTDRPYPAVADHRGATLAVEWP 5909 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFF 1314 A +Q VR +AR HNATSFMVV A LAVLL+KLS S DVAVGFPIAGR DPALD++VGFF Sbjct 5910 AELQDGVRELARAHNATSFMVVQAVLAVLLAKLSASSDVAVGFPIAGRRDPALDDVVGFF 5969 Query 1315 VNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVM 1374 VNTLVLRV+L G+P+ A++L QVR RSLAAYE+QDVPFEVLV+RL PTR+L HHPL+QVM Sbjct 5970 VNTLVLRVDLGGNPTVADVLAQVRRRSLAAYEHQDVPFEVLVERLNPTRSLGHHPLVQVM 6029 Query 1375 LAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVF 1434 LAWQ+N L+LGDLQ T +P+DTRTAR DL+FSLAER++ AGIGGAVE+RTDVF Sbjct 6030 LAWQNNEPVDLSLGDLQVTALPVDTRTARTDLLFSLAERWTGDGRSAGIGGAVEFRTDVF 6089 Query 1435 EAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSI 1494 + + L+ RLR+V+ A+A P R +SSID LD E ARL+ GN A L+ P P +SI Sbjct 6090 DTATVATLVARLRRVVAAMAEEPGRRLSSIDVLDEAEHARLEVVGNHAALSRPTPAGLSI 6149 Query 1495 PQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAP 1554 PQ+ A V R P+A A+ CGD S TY + D A+NRLAH L GAGPGE VALL R A Sbjct 6150 PQLFTASVNRSPDAVAINCGDRSWTYGQFDVAANRLAHLLIEHGAGPGERVALLIPRSAG 6209 Query 1555 AVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVV 1614 AV AM+AVLK+GAAY+PIDP P R+AFML D+ PVA +TT+GLRSRL G LP++++ Sbjct 6210 AVAAMLAVLKSGAAYVPIDPGLPAARIAFMLSDSAPVAVLTTSGLRSRLDGCGLPVLEID 6269 Query 1615 DALA-AYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVW 1673 D + PGT P P ++AYI+YTSGTTG PKGV +THRNV +L SL L QVW Sbjct 6270 DPVVDTLPGTALPPPRPEDVAYIIYTSGTTGIPKGVAVTHRNVAQLLDSLDDELELGQVW 6329 Query 1674 SQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAM 1733 +QCHS FD S WEI+GALL GGRLV+V ++V SP + + LLV E VSVL+QTP+A Sbjct 6330 TQCHSLAFDFSVWEIFGALLRGGRLVVVSDAVVRSPEELYALLVREQVSVLSQTPSAFDA 6389 Query 1734 LPT---------QGLESVALVVAGEACPAALVDRW---APGRV-MLNAYGPTETTICAAI 1780 L T Q L+ LV GEA A + RW PG ++N YG TETT+ A+ Sbjct 6390 LQTADALAPDLAQQLKLQTLVFGGEALEARRLGRWLDNHPGLPRLINMYGTTETTVHASF 6449 Query 1781 S--APLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLT 1838 G PIG P++ A FVLD WLRPVPAGV GEL++AG G+ GY R+GLT Sbjct 6450 RELGAGDVGGDASPIGGPLAHLAFFVLDRWLRPVPAGVVGELFVAGRGLACGYVGRSGLT 6509 Query 1839 ASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAEL 1898 SRFVACP G G RMYRTGDLV W ADGQL +LGR DDQVKIRG+RIELGE+ T L L Sbjct 6510 GSRFVACPSGPPGQRMYRTGDLVRWGADGQLRYLGRADDQVKIRGHRIELGEIHTVLTGL 6569 Query 1899 AGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDAL 1958 AGV +A VIAREDRPGDKRLVGY T G+ DPA +RA LA+RLP Y+VP+AVVV+DA+ Sbjct 6570 AGVKRAAVIAREDRPGDKRLVGYVT----GSADPAAIRAALAERLPAYMVPSAVVVVDAI 6625 Query 1959 PLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGD 2018 PLTVNGKLD RALPAP+Y YRAPA E+ +AGI+ARVLG++RVGVDDSFF+LGGD Sbjct 6626 PLTVNGKLDTRALPAPDYRGAAPYRAPATATEEILAGIYARVLGIDRVGVDDSFFDLGGD 6685 Query 2019 SLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRD 2058 SLAAMR+IAA+N LNA L VR+L A + L+ LG D Sbjct 6686 SLAAMRLIAAVNAGLNAHLGVRSLFEAPTIHLLAPRLGAD 6725 Score = 1292 bits (3343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 805/1602 (51%), Positives = 997/1602 (63%), Gaps = 101/1602 (6%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A A+++ TSGTTG PK V ++H ++ +A++ A QC L D SV E Sbjct 595 ADDVAHVIYTSGTTGVPKGVAVTHRNVTQLFEALAGDGLLSAGQVWSQCHSLAFDFSVWE 654 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 I+G G LV + + +L AL+ + R + + P+++ L + D + Sbjct 655 IWGALLHGGHLVVVPDALTRRADELRALL--VGQRVSVLTQTPSSLGAL------SPDGV 706 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQ--- 743 G + +V+G EA VD+W + G ++++ YGPTE T+ VA P+ Sbjct 707 GAA----LVVGAEACPAQVVDRW-----APGRAMVNVYGPTETTMWVAKSAPLAAGSGPP 757 Query 744 ---TTMDGALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLG---IDGDGFGTVTA 793 + +DGA L + RP+ P V GE+ + G V GYLG + G F Sbjct 758 GIGSPVDGAALFVLDAWLRPVPPGVV----GELYVAGSGVGVGYLGRAGLTGSRF-VACP 812 Query 794 ADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV 853 G+ R + TGD V D +G + GR D VKI G R+++ E+ + V AV Sbjct 813 FGGAGTRMYRTGDLVWWDPDGQLRYVGRADEQVKIRGYRIELGEIHSALMGLAGVEQAAV 872 Query 854 ELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGK 909 G V + + E A R+ +V + V +P +P NGK Sbjct 873 VAREDRPGDRRLVGYITGTADPAEVRARLGERLPGYMVPAAI-----VALPELPVTLNGK 927 Query 910 IDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIR 968 +D+ LP P++ G T L+ I+S+ LG +G D S G SL +R Sbjct 928 LDTRALP-APEYLGRGYRAPATFTEEV-LAGIYSQVLGLERVGVDDSFFDLGGDSLSAMR 985 Query 969 ILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFA 1028 ++ L LS+ L A T LA P G R +VA RP +PLSFA Sbjct 986 LVAAVNARLDVALSVRALFEAPTIRRLA-----PRLDGGGARLARVVAGARPEVVPLSFA 1040 Query 1029 QRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPR 1088 Q RLWFLDQL +PV+NMAVALRLRG LD + LG A ADVV RHESLRTVF A +G PR Sbjct 1041 QSRLWFLDQLHGCSPVHNMAVALRLRGRLDADVLGTAFADVVARHESLRTVFVAPEGTPR 1100 Query 1089 QLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVL 1148 Q+V+ A AD G +VDA WP RL AI+ A FDL TEIPLR LFR+ EHVL Sbjct 1101 QVVVPAAHADFGWQVVDAGGWPGARLAEAIDAVAHQPFDLTTEIPLRAKLFRVGAGEHVL 1160 Query 1149 VAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDS 1208 VAVAHHIAADGWS+ PL DL AYASRCAG P WA LPVQYVDYTLWQR GDL+D Sbjct 1161 VAVAHHIAADGWSITPLVRDLGIAYASRCAGAPPGWAELPVQYVDYTLWQRAQFGDLEDP 1220 Query 1209 DSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQH 1268 S I AQLAYW +ALAGMPERL +PT RPYP VAD RGA + V+WP +QQ+V +A +H Sbjct 1221 HSAITAQLAYWLDALAGMPERLEMPTDRPYPSVADYRGARVAVEWPPELQQRVSEVAGEH 1280 Query 1269 NATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDP 1328 NATSFMVV LA+LL+KL + DVAVGFPIAGR DPALD LVGFFVNTLVLR +L G+P Sbjct 1281 NATSFMVVQTALALLLAKLGATSDVAVGFPIAGRRDPALDELVGFFVNTLVLRTDLGGNP 1340 Query 1329 SFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ------DNPV 1382 + AE+L QV+ RSLAAYE+QDVPFEVLV+RL PTR+LTHHPLIQV+LAWQ D P Sbjct 1341 TVAEVLAQVQQRSLAAYEHQDVPFEVLVERLHPTRSLTHHPLIQVVLAWQNLPWQHDGPA 1400 Query 1383 GQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVL 1442 L LGD++ TP P+DT+ ARMDLVFSLAER++E PAGIGGA E+RTDVF+ +++ L Sbjct 1401 AGLALGDVRVTPEPVDTQVARMDLVFSLAERWTEDGRPAGIGGAAEFRTDVFDTASVEAL 1460 Query 1443 IERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQV 1502 +E+ R+VLVAV A P + +SSID LD E ARL GNRAVL P+ VSIP++ AAQV Sbjct 1461 VEQFRRVLVAVTADPTKRISSIDVLDEAEHARLAVVGNRAVLHGPSRAGVSIPELFAAQV 1520 Query 1503 ARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAV 1562 R P+A A+ C S TY ELDE SNRLAH L GAGPGECVALL ER A AV AM+AV Sbjct 1521 DRAPDAVAITCAQRSWTYGELDETSNRLAHLLIEYGAGPGECVALLAERSAQAVAAMLAV 1580 Query 1563 LKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD---ALAA 1619 LKTGAAYLPIDP P R+ F+LGDA P+AA+ T G+RSRL G DL +DV D A + Sbjct 1581 LKTGAAYLPIDPGLPAARIEFLLGDAAPIAAIVTPGMRSRLDGSDLTALDVDDPAVATQS 1640 Query 1620 YPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSY 1679 G P P A N+AY++YTSGTTG PKGV +TH NVT+L S+ +VWSQCHS Sbjct 1641 TDGLSP--PDAENVAYVIYTSGTTGVPKGVAVTHHNVTQLLESVDREFELGRVWSQCHSL 1698 Query 1680 GFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAML---PT 1736 FD S WEI+GALL G RLVIVP+ V SP D H +LV E VSVL+QTP+A L P+ Sbjct 1699 AFDFSVWEIFGALLRGARLVIVPDDVVRSPEDLHAMLVRERVSVLSQTPSAFYALSPEPS 1758 Query 1737 QGLESVALVVAGEACPAALVDRWAPGRV----MLNAYGPTETTICAAISAPLRP--GSGM 1790 + L+ +V GEA + RW R ++N YG TETT+ A+ G Sbjct 1759 E-LKLQTVVFGGEALEPPRLGRWLHNRPKLPRLINMYGITETTVHASFREITEADVGDTT 1817 Query 1791 PPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGS 1850 PIG P++ FVLD WL PVPAGV GELY+AG GV GY RAGLTASRFVACPFG Sbjct 1818 SPIGAPLAHLGFFVLDEWLHPVPAGVTGELYVAGGGVACGYGGRAGLTASRFVACPFGAF 1877 Query 1851 GARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIARE 1910 G+RMYRTGDLV W ADG+L++LGR D+QVKIRGYRIELGE+ AL V QA V+ARE Sbjct 1878 GSRMYRTGDLVRWGADGRLQYLGRADEQVKIRGYRIELGEIRAALTAFDEVEQAAVVARE 1937 Query 1911 DRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRA 1970 DRPGDKRLV Y T G DPA +RA+LA RLPGY+VPAAVV +DA+PLT+NGKLD RA Sbjct 1938 DRPGDKRLVAYVT----GTADPAHVRARLADRLPGYMVPAAVVAVDAIPLTLNGKLDTRA 1993 Query 1971 LPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAIN 2030 LPAP+Y + YRAPA PVE+ +AGI+ARVLGLERVGV++SFF+LGGDSL+AMR++AA Sbjct 1994 LPAPDYQEGGEYRAPATPVEEILAGIYARVLGLERVGVEESFFDLGGDSLSAMRLVAAAA 2053 Query 2031 TTLNADLPVRALLHASSTRGLSQLLG----------RDARPTSDP------RLV---SVH 2071 T L+A L VR L A + R L+ LG ARP P RL + Sbjct 2054 TGLDARLEVRTLFEAPTIRQLAPRLGAGGGRAARVVAGARPAVVPLSFAQSRLWFTGQLQ 2113 Query 2072 GDNPTEVHASDLTLDRFIDADTLATAV-NLPGPSPELRTVLL 2112 G +P A+ + LD +D + L A+ ++ LRTV + Sbjct 2114 GPSPVYNMAAAMRLDGRVDVEALRAALGDVVARHESLRTVFM 2155 Score = 800 bits (2067), Expect = 0.0, Method: Compositional matrix adjust. Identities = 519/1048 (50%), Positives = 644/1048 (62%), Gaps = 65/1048 (6%) Query 1023 IPLSFAQRRLWFLDQLQRPA--PVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F R VY + + + + G LD + L AV V+ RH +L F Sbjct 4664 LPLTPLQQGLLFHANTGRDPGDDVYAVQLDITVCGPLDPQRLREAVHTVLHRHPNLIARF 4723 Query 1081 -----PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQR--AIEEAARHSFDLATEIP 1133 V +P + + R L D D P R+ + A E AA DLA Sbjct 4724 CDDFDEPVQIIPPEPAMAWRYLQLDADDTD----PDGRIGQLSAAERAA--VCDLAAGPA 4777 Query 1134 LRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVD 1193 R L R + H V HHI DGWS+ + ++ A Y R P AP Y Sbjct 4778 FRAALIRTGEARHRFVLTVHHIVMDGWSLPIVLQEIFAGYFRE---RMPAAAP----YRR 4830 Query 1194 YTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDW 1253 Y W L D D P A A W+ L G PT P +RG + Sbjct 4831 YLTW-------LADRDVP--AARAAWQQVLDG----FDTPTLVRPPGRVGRRGVA-TFSV 4876 Query 1254 PASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPA----LDN 1309 PA + + +AR T V+ AG A +L+ L+G DV G ++GR PA ++ Sbjct 4877 PAVTTRALGGLARSSLTTVSTVLQAGWAQVLAWLTGQDDVVFGAVVSGR--PADVRGAES 4934 Query 1310 LVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHP 1369 +VG +NT+ +R L + A LL Q+R E+Q + + RA H Sbjct 4935 MVGLLINTVPVRATLTAATTVAGLLEQLRRAQNHTLEHQHLALPEI------HRATGHEQ 4988 Query 1370 LIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 L + +++ P+ + L A + + T+R + L+ + G E +G VE+ Sbjct 4989 LFDTLFVYENYPIDRAALAG--AHEVTVTDFTSREFNHYPLSVQAVPGDE---LGLRVEF 5043 Query 1430 RTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAP 1489 T+VF+A I +IER R+VL A+AA P R +S+IDALD +E L WGNRAVLT P Sbjct 5044 DTEVFDADGIAAMIERFRRVLEAMAADPARPLSTIDALDESEHVHLGAWGNRAVLTEPV- 5102 Query 1490 TPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLF 1549 T SIP+ A QVAR P+A A+ S+TYRELDEA+NRLAH LA GAGPG VALLF Sbjct 5103 TGASIPEAFAVQVARSPDAVALRFEGRSLTYRELDEAANRLAHLLAERGAGPGTFVALLF 5162 Query 1550 ERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLP 1609 R A A+VAM+AVLK+GAAYLPIDP P R+ FM+ DA P+ A+TTA LR RL G L Sbjct 5163 SRSADAIVAMLAVLKSGAAYLPIDPGLPDARIRFMIADASPIVALTTAELRPRLDGSALT 5222 Query 1610 IIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS 1668 +IDV D ++ A P T PP PA ++AY++YTSGTTG PKGV +TH NVT+L ASL A L Sbjct 5223 VIDVHDPSVTARPATAPPAPAPEDIAYLIYTSGTTGAPKGVAVTHHNVTQLMASLHAPLP 5282 Query 1669 AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 AA VWSQCHS FD S EI+GALL GGRLV+VPE V SP D LL+ E VSVL+QTP Sbjct 5283 AAGVWSQCHSPAFDVSVQEIFGALLDGGRLVVVPEPVVHSPEDLRALLIRERVSVLSQTP 5342 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 + L +GL++VALV+ GE CP LVDRWAPGRVM+NAYGPTETT+ AAISAPL G+ Sbjct 5343 SEAGALSPEGLDAVALVIGGEPCPDELVDRWAPGRVMVNAYGPTETTVDAAISAPLTAGA 5402 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 G PIG PVSGAAL VLD WLRPVPAGV GELY+AG GV GY R+GLTASRF+ACPFG Sbjct 5403 GA-PIGSPVSGAALLVLDKWLRPVPAGVVGELYVAGRGVACGYLGRSGLTASRFIACPFG 5461 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 G GARMYRTGDLV W DGQL ++GR DDQVKIRG+R+ELGE+ TAL LAGV +A VIA Sbjct 5462 GPGARMYRTGDLVRWGTDGQLRYVGRADDQVKIRGHRVELGEIHTALTALAGVERAAVIA 5521 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 R D RLVGY T G DPAG RA LA+RLP Y+VPAA+V +DA+PLTVNGKLD Sbjct 5522 R-----DGRLVGYIT----GTADPAGARAALAERLPAYMVPAAIVEVDAIPLTVNGKLDA 5572 Query 1969 RALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAA 2028 RALPAPEY D + YRAPA P+E +A I+AR+LGL RVGVD+SFF+LGGDSLAAMR+ AA Sbjct 5573 RALPAPEYHDADAYRAPANPIEGILAEIYARILGLARVGVDESFFDLGGDSLAAMRLAAA 5632 Query 2029 INTTLNADLPVRALLHASSTRGLSQLLG 2056 +N L+A L VR +L A + R L+ LLG Sbjct 5633 VNAGLDAQLSVRTVLEAPTVRRLAPLLG 5660 Score = 727 bits (1876), Expect = 0.0, Method: Compositional matrix adjust. Identities = 490/1134 (44%), Positives = 634/1134 (56%), Gaps = 90/1134 (7%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A+PL+ Q +W + + + + + + G + +AL A+ + E R F Sbjct 7 ALPLTCGQLDIWLSQETGHSGTQWQIGLFVTIDGGVQRDALKWAIRQALQEAEPARASFA 66 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLA-TEIPL-----R 1135 DG Q ++ +L D + P A+EEA R + + T +P R Sbjct 67 EADGQVFQRAVDYPDVELAFH--DLSGSP-----DAVEEARRIALSIQRTPMPFAGPLFR 119 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 LFR D+ L A HHI DG VA + +++ Y++ + AP+P Sbjct 120 FALFRTRADQFHLFACCHHIILDGTGVALVGHRIASIYSAIVSA-----APIPAPVFGS- 173 Query 1196 LWQREILGDLDDSDSPIAAQL------AYWENALA---GMPERL-RLPTAR-PYP--PVA 1242 L DL D +S A AYW L G+P R R R P+P PVA Sbjct 174 ------LRDLVDYESRYEASADYRRDEAYWIRHLPADDGVPHRAPRAAGDRDPWPSAPVA 227 Query 1243 DQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSG-SPDVAVGFPIAG 1301 G V ++V +++R + V+ A A+L+ SG P+V + FP+ Sbjct 228 LDSG----------VLRRVDKLSRVWGVSQTSVITAACALLVRGWSGDGPEVVLDFPVNR 277 Query 1302 RSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKP 1361 R P L G + L + L+ + + AE QV R A E+Q P + L + + Sbjct 278 RVRPEAKTLPGMLAGVVPLVLRLSPELTVAEFCRQVDTRVREALEHQRFPVQALERKARG 337 Query 1362 TRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPA 1421 + + A P G G + + + L+FS S+G Sbjct 338 AAGPAERVSVNFVPAAFTLPFG----GVTASASYTNSGQVTGLGLIFS-----SDGDRLF 388 Query 1422 GIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNR 1481 V F+A L RL ++LVA+ A R + SID LD +R RL WGN Sbjct 389 LSTAGVWEPFSGFDAAD---LAGRLERLLVALTADTTRRLLSIDVLDEADRVRLAGWGNW 445 Query 1482 AVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGP 1541 AV+ AP +IP+ Q R P A A+ C +YRE+DEASNRLA L G G G Sbjct 446 AVMGRAAPAGRTIPEWFGVQAGRSPSAVAISCEGRRWSYREVDEASNRLARWLIGRGVGR 505 Query 1542 GECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRS 1601 V LL ER A AV+A++ VLK GAAY+P+DP P RV FML DA P A + +AGLR Sbjct 506 RARVGLLMERSAEAVIAVLGVLKAGAAYVPMDPGLPAGRVEFMLADAAPAAVIVSAGLRP 565 Query 1602 RLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLF 1660 RL + DV D + P P+A ++A+++YTSGTTG PKGV +THRNVT+LF Sbjct 566 RLGEFAGVVADVDDPVIRQQPAAGVAGPSADDVAHVIYTSGTTGVPKGVAVTHRNVTQLF 625 Query 1661 ASLPAR--LSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVA 1718 +L LSA QVWSQCHS FD S WEIWGALL GG LV+VP+++ ++ LLV Sbjct 626 EALAGDGLLSAGQVWSQCHSLAFDFSVWEIWGALLHGGHLVVVPDALTRRADELRALLVG 685 Query 1719 EHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICA 1778 + VSVLTQTP+++ L G+ ALVV EACPA +VDRWAPGR M+N YGPTETT+ Sbjct 686 QRVSVLTQTPSSLGALSPDGV-GAALVVGAEACPAQVVDRWAPGRAMVNVYGPTETTMWV 744 Query 1779 AISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLT 1838 A SAPL GSG P IG PV GAALFVLD+WLRPVP GV GELY+AG+GVGVGY RAGLT Sbjct 745 AKSAPLAAGSGPPGIGSPVDGAALFVLDAWLRPVPPGVVGELYVAGSGVGVGYLGRAGLT 804 Query 1839 ASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAEL 1898 SRFVACPFGG+G RMYRTGDLV W DGQL ++GR D+QVKIRGYRIELGE+ +AL L Sbjct 805 GSRFVACPFGGAGTRMYRTGDLVWWDPDGQLRYVGRADEQVKIRGYRIELGEIHSALMGL 864 Query 1899 AGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDAL 1958 AGV QA V+AREDRPGD+RLVGY T G DPA +RA+L +RLPGY+VPAA+V + L Sbjct 865 AGVEQAAVVAREDRPGDRRLVGYIT----GTADPAEVRARLGERLPGYMVPAAIVALPEL 920 Query 1959 PLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGD 2018 P+T+NGKLD RALPAPEY GYRAPA E+ +AGI+++VLGLERVGVDDSFF+LGGD Sbjct 921 PVTLNGKLDTRALPAPEY-LGRGYRAPATFTEEVLAGIYSQVLGLERVGVDDSFFDLGGD 979 Query 2019 SLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLL----GRDARPTSDPR-------- 2066 SL+AMR++AA+N L+ L VRAL A + R L+ L R AR + R Sbjct 980 SLSAMRLVAAVNARLDVALSVRALFEAPTIRRLAPRLDGGGARLARVVAGARPEVVPLSF 1039 Query 2067 -------LVSVHGDNPTEVHASDLTLDRFIDADTLATAV-NLPGPSPELRTVLL 2112 L +HG +P A L L +DAD L TA ++ LRTV + Sbjct 1040 AQSRLWFLDQLHGCSPVHNMAVALRLRGRLDADVLGTAFADVVARHESLRTVFV 1093 Score = 101 bits (252), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 189/748 (26%), Positives = 293/748 (40%), Gaps = 105/748 (14%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCD-----------TADEI---S 520 L++ GA PG+ + + + + + ++A G Y D AD I + Sbjct 3657 LIEYGAGPGECVALLAERSAQAVAAMLAVLKTGAAYLPIDPGLPTARIEFMLADAIPIAA 3716 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 V T + DG + LAV+ D+ DA AY++ T Sbjct 3717 VTTAGVRSRLDG----------SDLAVLDFDDPELATQPGGPPPPPDA---ENVAYVIYT 3763 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V ++H ++ +++ R G QC L D SV EIFG GAR Sbjct 3764 SGTTGVPKGVAVTHHNVTQLLESVDRELELG--RVWSQCHSLAFDFSVWEIFGALLRGAR 3821 Query 641 LVRSAAMKTGDLAALVDDLVA-----RETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQI 695 LV + D+ +DL A R T + P+AV L D++ + Sbjct 3822 LV----IVPDDVVRSPEDLHAMLVRERVTVLSYTPSAVAGLAPQGLDSV--------ATL 3869 Query 696 VIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFL-PIVCDQTT------MDG 748 V+GGE VD+W + G +++ YGPTE T+ A P+ T + G Sbjct 3870 VMGGEPCPPEVVDRW-----APGRVMVNQYGPTETTMYAAMTAPLTAGAGTPPIGSPVPG 3924 Query 749 ALL----RLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAA-----DGSRR 799 A L R RP+ V GE+ + G VA GY G G A D + Sbjct 3925 AALFVLDRWLRPVPEGVV----GELYVAGRGVARGYPGRPGLTASRFVACPFGGPDAPGQ 3980 Query 800 RAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGS 859 R + TGD D++G + GR D VKI G R+++ E+ + V V + Sbjct 3981 RMYRTGDLARWDSDGQLHYLGRMDDQVKIRGYRIELGEIRAALTGLRGVGQAVVIVREDR 4040 Query 860 LG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNL 915 G V + + A R+ +V + V + +IP NGK+D L Sbjct 4041 PGYKRLVAYVTGTADPAHLRGRLADRLPNYMVPAAI-----VALDDIPLTLNGKLDIRAL 4095 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 P P + +A A L+ I+++ LG +G D S G S+ ++++ R Sbjct 4096 P-APDFESAEHYRAPGDAVEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARAR 4154 Query 975 RYLGWRLSLLDLIGADTAANLADYAPTP-DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLW 1033 G D+ T A LA A D ++ P+ AA P+ + Sbjct 4155 -AAGVVFRPRDVFVEQTVARLARVAGVAIDDRAVDEGVGPV------AATPI------MR 4201 Query 1034 FLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIE 1093 +L + P +N + +R + + + A + ++ RH LR DG + Sbjct 4202 WLHSVDGPVEEFNQTMIVRAPDGVTHDDVVALLQALIDRHPMLRLCVDD-DGAGGWTL-- 4258 Query 1094 ARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAVA 1152 A+ G + L R A R + A + LR W A+ L + Sbjct 4259 -HAAEPGAIQAGGCVHAVEALTREALVAERSRLNPAAGVMLRAVW----AEPTGRLALIV 4313 Query 1153 HHIAADGWSVAPLTADLSAAYASRCAGR 1180 HH+A DG S L DL+ A+A + +GR Sbjct 4314 HHLAVDGVSWRILLEDLNIAWAQQQSGR 4341 >gi|342860889|ref|ZP_08717539.1| syringomycin synthetase [Mycobacterium colombiense CECT 3035] gi|342131913|gb|EGT85170.1| syringomycin synthetase [Mycobacterium colombiense CECT 3035] Length=5350 Score = 2025 bits (5246), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1150/2073 (56%), Positives = 1390/2073 (68%), Gaps = 70/2073 (3%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L+ GA PG + + + + + ++A G Y D A + R D L Sbjct 3309 LIDEGAGPGQYVAVLMERSAQAVVAILAVLKTGAAYLPIDPA---APRNRVGFMLADARL 3365 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALL----ATKTAYIMPTSGTTGQPKLV 590 V + AA + + G VDE + L A AY++ TSGTTG PK V Sbjct 3366 VAAISTAALRSVLDGFGVAVIDVDEAAAHARPYSALPPTAAADIAYVIYTSGTTGTPKGV 3425 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTG 650 ++H ++A ++ R QC L D SV EIFG G RL+ Sbjct 3426 AVTHRNVAELLGSV-RGRLTSTTGVWSQCHSLAFDFSVWEIFGALLHGGRLLVVPDDVVR 3484 Query 651 DLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDK 709 L D L+ + +++ P+A + L AD A + R +V GGEA+ + K Sbjct 3485 SPEDLCDLLIDEDVSVLSQTPSAFFALQSAD--ASRSGRRLSPHTVVFGGEALVPQRLGK 3542 Query 710 WLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL----- 764 W+ + L++ YG TE TV A+F IV + +DG +G+P+ F+ Sbjct 3543 WVHNHPRHP-RLVNMYGITETTVHASFREIV--EADIDGHGSPIGKPLAHLGFFVLDAWL 3599 Query 765 ------AFGEVVIVGDLVADGYLGIDGDGFGTVTAAD--GSRRRAFATGDRVTVDAEGFP 816 GE+ + G VA GYLG G A G R + TGD V +G Sbjct 3600 RPVPAGVLGELYVAGAGVAAGYLGRAGLTASRFVACPFAGGGARMYRTGDVVCWGHDGQL 3659 Query 817 VFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRTREG 872 + GR D VK+ G R+++ E+ I E V AV G V + + Sbjct 3660 QYVGRADDQVKVRGYRIELGEIQSAITELEGVGQAAVIAREDRPGEKRLVGYVTGTADPA 3719 Query 873 EQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETG 932 E A A R+ +V V V + +P PNGK+D+ LP P + +A T Sbjct 3720 EVRAQLAERLPAYMVPAAV-----VAIEALPLTPNGKLDARALPA-PDYHGIDQYSAPTT 3773 Query 933 QRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADT 991 ++ I++ LG +G D S G SL +R++ E L L + L A T Sbjct 3774 AVERTMADIYAHVLGVDRVGIDDSFFDLGGDSLSAMRLVAEVNTNLDVHLGVRALFEAPT 3833 Query 992 ----AANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNM 1047 AA L D G DR PLVA RP +PLSFAQ RLWF+ QL P+PV+NM Sbjct 3834 IRRLAARLGD--------GGGDRL-PLVAGARPEVVPLSFAQSRLWFIGQLHGPSPVHNM 3884 Query 1048 AVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDAT 1107 A+ALRL G LD +A GAA+ADVV RHESLRT+FPA G+P+QLV+E AD G I DA Sbjct 3885 AMALRLHGRLDGDAFGAALADVVARHESLRTLFPAHGGIPQQLVVEVDDADFGWQISDAR 3944 Query 1108 AWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTA 1167 W + RL +AI+ H FDLATE+PLR LFR+ D+E++LVAV HHIAADGWS+ PL Sbjct 3945 GWSSTRLSKAIDTVVAHRFDLATELPLRALLFRLNDNEYLLVAVLHHIAADGWSLTPLVR 4004 Query 1168 DLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMP 1227 DL AYASR G APDWAPLPVQYVDYTLWQR G+L D S IA QL YWE+ LAGMP Sbjct 4005 DLGEAYASRVLGDAPDWAPLPVQYVDYTLWQRAQFGELQDPHSLIAGQLRYWEHTLAGMP 4064 Query 1228 ERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKL 1287 ERL LPT RPYP VAD GAS+ VDWPA +QQ+VR +A HNATSFMVV A LAVLL+K+ Sbjct 4065 ERLELPTDRPYPLVADFAGASVAVDWPAELQQRVRAVATAHNATSFMVVQAALAVLLAKV 4124 Query 1288 SGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYEN 1347 S S DVAVGFPIAGR DPALD++VGFFVNTLVLRV+LAGDP+ AE+L VRARSLAAYE+ Sbjct 4125 SASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDLAGDPTIAEVLAHVRARSLAAYEH 4184 Query 1348 QDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLV 1407 QDVPFEVLV+RL PTR+L HHPL+QVMLAWQ+ +L+LGD++ TP+P+DTRTARMDL Sbjct 4185 QDVPFEVLVERLNPTRSLAHHPLVQVMLAWQNTDSAELSLGDVRVTPVPVDTRTARMDLA 4244 Query 1408 FSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDAL 1467 +SLAER++ +P GIGGAVE+RTDVF+ I+ L+ RL +VL A+ A P + +SSID L Sbjct 4245 WSLAERWTPDGQPGGIGGAVEFRTDVFDTATIEALVTRLHRVLTAITADPAQRLSSIDVL 4304 Query 1468 DGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEAS 1527 E RLD GNRA LT P+ P SIP++ A VAR PEA A+ G S TYREL+E + Sbjct 4305 GADEHTRLDAIGNRAALTRPSHRPASIPEVFAGHVARTPEAVAIRYGACSWTYRELEEHA 4364 Query 1528 NRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGD 1587 NRLAH L GAGPG+CVALL ER A AV A++AVLKTGAAY+PIDPA P R+ FML D Sbjct 4365 NRLAHVLVDHGAGPGQCVALLLERSARAVAAILAVLKTGAAYVPIDPALPAARIEFMLTD 4424 Query 1588 AVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEP 1646 A P A +TTA RSR+ +ID+ D A+ A P T P PA +AY +YTSGTTG P Sbjct 4425 AAPTAVLTTAESRSRIGDSGPLVIDIDDPAIQARPTTALPAPAPHGVAYTIYTSGTTGVP 4484 Query 1647 KGVGITHRNVTRLFASL-PARLSAA--QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPE 1703 KGV +TH N T+LFASL A L AA +VWSQCHS FD S WEI+GALL GGR+++VP+ Sbjct 4485 KGVAVTHHNATQLFASLGAAGLPAAPGKVWSQCHSLAFDFSVWEIFGALLHGGRVLVVPD 4544 Query 1704 SVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGR 1763 V SP D H LLVAE V +LTQTP+ ML T GL+S L VAGEACP LVDRWA GR Sbjct 4545 EVVRSPKDLHALLVAEGVDMLTQTPSEAGMLATDGLDSTVLAVAGEACPTELVDRWAAGR 4604 Query 1764 VMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIA 1823 VM+N YGPTE TI AA+SAPL PG +PPIG P+SGAALFVLD L+PVPAGV GELY+A Sbjct 4605 VMVNVYGPTEITIVAAVSAPLVPGPEVPPIGSPLSGAALFVLDGCLQPVPAGVVGELYVA 4664 Query 1824 GAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRG 1883 G GV GY RR+GLTASRFVACPFGG+GARMYRTGDL W DGQL + GR D+QVKIRG Sbjct 4665 GGGVSTGYLRRSGLTASRFVACPFGGTGARMYRTGDLAWWGTDGQLRYAGRADEQVKIRG 4724 Query 1884 YRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRL 1943 YRIELGE+ ALA L GV +A VIAREDRP RLVGY T G +PA +R LA+RL Sbjct 4725 YRIELGEIQAALAALDGVDRAFVIAREDRPAALRLVGYVT----GTANPAEIRTLLAERL 4780 Query 1944 PGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGL 2003 P Y+VPAAVVV+ LPLT GKLD R+LPAP+Y + Y APA VE+ +A ++A+VLGL Sbjct 4781 PAYMVPAAVVVLPVLPLTPGGKLDTRSLPAPDYQGADDYLAPATAVEEILAWLYAQVLGL 4840 Query 2004 ERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTS 2063 ERVGV +SFF+LGGDSL+AMR++AAI L+ LPVRA+ A S R LSQ L D Sbjct 4841 ERVGVSESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVFEAPSVRSLSQQLNADHGAAE 4900 Query 2064 DPR--LVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGR 2121 R SVHG + TEV+ASDLTLD+FIDA TL+ A LPGP ++RTVLLTGATGFLGR Sbjct 4901 GLRADFASVHGRDATEVYASDLTLDKFIDAPTLSGAAALPGPGAQVRTVLLTGATGFLGR 4960 Query 2122 YLVLELLRRLDV-DGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVA 2180 YLVL+ L RL++ DG+LICLVRA SD+DARRRLEKTFDSGDP LLR+F ELA D LEV+A Sbjct 4961 YLVLQWLERLELADGKLICLVRATSDQDARRRLEKTFDSGDPALLRYFHELADDHLEVIA 5020 Query 2181 GDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTK 2239 GDK DLG+D+ WRRLA+TVDLIVD AA+VN PY ELFGPNVAGTAELIR+ALTTK Sbjct 5021 GDKGRADLGVDEQTWRRLADTVDLIVDCAAVVNGVLPYSELFGPNVAGTAELIRLALTTK 5080 Query 2240 LKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREAND 2299 LKP+TYVSTA+VG I+PSAFTEDADIR P RT+DG + GYG SKWAGEVLLREAND Sbjct 5081 LKPYTYVSTANVGDQIDPSAFTEDADIRTAGPIRTIDGSYGNGYGNSKWAGEVLLREAND 5140 Query 2300 LCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAH 2359 LC LPV+VFRC MILADT+YAGQLN+SD TRMV S++A+G+APRSFYE D++GNRQRAH Sbjct 5141 LCGLPVSVFRCDMILADTTYAGQLNLSDMFTRMVHSVVASGVAPRSFYELDAQGNRQRAH 5200 Query 2360 FDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRI 2419 FD LPV FVAEAI LGA+V + G+ TYHVMNPHDDGIGLDEYVDW++EAGYP+RR+ Sbjct 5201 FDALPVEFVAEAITTLGAQV----MDGYETYHVMNPHDDGIGLDEYVDWVVEAGYPVRRV 5256 Query 2420 DDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRA 2479 DDF EWLQR EA+L ALP+RQR SVL +L ++Q + P P RGC APTDRFRAAV+ Sbjct 5257 DDFTEWLQRMEAALHALPERQRHQSVLQLLQLRSAQHVPPADPARGCLAPTDRFRAAVQE 5316 Query 2480 AKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 AK+G D DIP +S I+ YVT+LQLLGLL Sbjct 5317 AKIGPDN---DIPQISPSVIVKYVTDLQLLGLL 5346 Score = 1354 bits (3504), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/1271 (58%), Positives = 891/1271 (71%), Gaps = 29/1271 (2%) Query 767 GEVVIVGDLVADGYLGIDGDGFGTVTAA--DGSRRRAFATGDRVTVDAEGFPVFSGRKDA 824 GE+ + G V GYLG G A +R + TGD V A+G + GR D Sbjct 15 GELYVAGAGVGVGYLGRAGLSASRFVACPFGAPGQRMYRTGDLVRWGADGQLRYFGRADE 74 Query 825 VVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRTREGEQDAAAAT 880 VK+ G R+++ E+ +AE V AV + +G V + + + A Sbjct 75 QVKVRGYRIELGEIRTALAELDGVERAAVLVREDRVGDKRVVGYVTGAADPADIRARLGQ 134 Query 881 RIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQ 940 R+ +V V V + +P NGK+D+ LP G ET L+ Sbjct 135 RLPTYMVPAAV-----VVLDALPVTLNGKLDTRALPAPEYQGGHGYRAPETAIEEI-LAG 188 Query 941 IWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYA 999 I++R L +G D S G SL +R++ L L + L A T A LA Sbjct 189 IFARVLNVDRVGIDDSFFHLGGDSLSAMRLVSAINTGLDAHLGVRILFEAPTVAQLA--- 245 Query 1000 PTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDT 1059 P G R L +RPA +PLSFAQ RLWF+DQ Q P+PVYNMAVAL+L G ++T Sbjct 246 --PRVEAGVGRADRLAPTERPALLPLSFAQSRLWFIDQFQGPSPVYNMAVALKLNGPVNT 303 Query 1060 EALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIE 1119 +A+GAA+ DVV RHESLRT+F A +G P+Q+++ R+D+ +VDAT WPA L A + Sbjct 304 DAMGAALRDVVARHESLRTLFVAPEGTPQQVIVAPERSDVSWQVVDATRWPASWLAEATQ 363 Query 1120 EAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAG 1179 EAAR++FDLA EIPLR WLF+ DDEHVLVAV HHIAADGWS+ PL DL AAYA R G Sbjct 364 EAARYTFDLANEIPLRAWLFQTGDDEHVLVAVVHHIAADGWSLTPLVRDLGAAYAIRSTG 423 Query 1180 RAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYP 1239 R PDWAPLPVQY DYTLWQR GDL+D SPIA QLAYWE ALAG+PE + LPT RPYP Sbjct 424 RTPDWAPLPVQYADYTLWQRAHFGDLEDPASPIAGQLAYWEQALAGLPEHVELPTDRPYP 483 Query 1240 PVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPI 1299 AD RG+S+ V WPA +QQ+V R+A HNAT FMVV A L VLL KLS S DVAVGFPI Sbjct 484 LAADYRGSSVDVQWPAELQQRVARLAHTHNATGFMVVQAALVVLLGKLSASSDVAVGFPI 543 Query 1300 AGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRL 1359 AGRSDPALD++VGFFVNTLVLRV+L GDPS AELL +VR RSLAAYE+QDVPFEVLV+RL Sbjct 544 AGRSDPALDDVVGFFVNTLVLRVDLGGDPSVAELLDRVRQRSLAAYEHQDVPFEVLVERL 603 Query 1360 KPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSE 1419 P+R+L HHPL+QVMLAWQ+N L+LGD+Q TP+P++T+ ARMDLVFSLAER+++ + Sbjct 604 NPSRSLAHHPLVQVMLAWQNNDPVDLSLGDVQVTPLPLETQVARMDLVFSLAERWTDDGQ 663 Query 1420 PAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWG 1479 PAGI G VE+RTDVF+A +I+ L+ RLR+VL +A P R +SSID LD +E RL E G Sbjct 664 PAGIAGTVEFRTDVFDAASIETLVARLRQVLSGMADDPARPLSSIDILDASEHTRLHEIG 723 Query 1480 NRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGA 1539 NRAVL P VSIP + A QVAR P A A+ CG S TYRELDE++NRLAH L G GA Sbjct 724 NRAVLARPPRGTVSIPALFAGQVARTPGAVAITCGRRSWTYRELDESANRLAHMLVGRGA 783 Query 1540 GPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGL 1599 GPG VA++ R A A+VA++AVLKTGAAY+PIDPA P R+ FML DA P+A V+TA Sbjct 784 GPGRRVAVMIPRSADAIVAILAVLKTGAAYVPIDPALPLARIEFMLTDAAPIATVSTAEF 843 Query 1600 RSRLAGHDL--PIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNV 1656 +RL D+ P+ID+ D + +P T P P A N+AY++YTSGTTG PKGV +TH NV Sbjct 844 PARL---DISGPLIDIDDPGVRTHPSTGLPAPTADNIAYVIYTSGTTGTPKGVAVTHHNV 900 Query 1657 TRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLL 1716 T+L S+ A+L QVWSQCHS FD S WE++G+LL GGRLV+VP+ V SP D H LL Sbjct 901 TQLLQSVDAQLGLGQVWSQCHSLAFDFSVWELFGSLLRGGRLVVVPDQVVRSPEDLHALL 960 Query 1717 VAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTI 1776 +AE V+VL+QTP+A A+LP+ GLESVAL+V GE CP ++DRWAPGRVM+N YGPTETT+ Sbjct 961 IAERVNVLSQTPSAAAVLPSDGLESVALIVGGEPCPLEVMDRWAPGRVMVNQYGPTETTM 1020 Query 1777 CAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAG 1836 AA++ PL G PIG PV GAALFVLD WLRPVP GV GELYIAG GV GY RAG Sbjct 1021 YAAMTVPLTAGLDSVPIGSPVPGAALFVLDHWLRPVPPGVVGELYIAGRGVATGYLGRAG 1080 Query 1837 LTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALA 1896 LTASRFVACPFGGSGARMYRTGDLV W AD QL++LGR D+Q+KIRGYRIELGE+ + L Sbjct 1081 LTASRFVACPFGGSGARMYRTGDLVRWGADAQLDYLGRADEQIKIRGYRIELGEIHSVLT 1140 Query 1897 ELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVID 1956 EL G+ QA VIARED P RLVGY T G DP+ +R+QLA+RLP Y+VPAAVV +D Sbjct 1141 ELEGIEQAAVIAREDHPAAVRLVGYVT----GTADPSEVRSQLAERLPPYMVPAAVVTLD 1196 Query 1957 ALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELG 2016 ALPLTVNGKLD RALPAP+YG N YRAPA +E+ +AGI+A+VLGLERVG+DDSFF+LG Sbjct 1197 ALPLTVNGKLDTRALPAPDYG-INEYRAPADAIEEILAGIYAQVLGLERVGIDDSFFDLG 1255 Query 2017 GDSLAAMRVIA 2027 GDS+ +M+V+A Sbjct 1256 GDSILSMQVVA 1266 Score = 1331 bits (3445), Expect = 0.0, Method: Compositional matrix adjust. Identities = 808/1614 (51%), Positives = 1004/1614 (63%), Gaps = 109/1614 (6%) Query 576 YIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYG----WGAHDTVLQCAPLTSDISVEEI 631 Y++ TSGTTG PK V ++H ++ A+ A W QC D+S++EI Sbjct 2365 YVIYTSGTTGVPKGVAVTHRNVTQLLPALHAALPAAGVWS------QCHSYGFDVSIQEI 2418 Query 632 FGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIG 688 +G A G RLV S +L AL+ + R + + P+A+ L D Sbjct 2419 WGALAGGGRLVIVPESVTRSPDELHALL--IAERVSVLSHTPSALAALSPQHLDT----- 2471 Query 689 RSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDG 748 ++IGGE + D+W ++++YGPTE TV A ++ G Sbjct 2472 -----ALIIGGEPCPPALADRWAPRRV-----MINAYGPTETTVDA----VLSAPLAAGG 2517 Query 749 ALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYL---GIDGDGFGTVTAA 794 LG P+ +F+ GE+ + G VA GY G+ F Sbjct 2518 GAPPLGSPVSGAALFVLDGWLRPVPAGVIGELYVAGAGVAVGYARRAGLTASRF-VACPF 2576 Query 795 DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVE 854 G R + TGD V +G + GR D VKI G R+++ E+ +AE V V Sbjct 2577 GGVGARMYRTGDLVRWAPDGRLHYVGRADEQVKIRGHRIELGEIRSALAELDGVGQTVVI 2636 Query 855 LHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKI 910 G V + + + A R+ +V V + + +P PNGK+ Sbjct 2637 AREDRPGQKRIVAYLTGTAEAADVRDRLAARLPAYMVPAAV-----IAIEAVPLTPNGKL 2691 Query 911 DSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRI 969 D+ LP P+ +A G A +G L+ I++ LG +G D S G SL +R Sbjct 2692 DARALPA-PEHTA-GAYRAPSGAVEEILAGIYADVLGLERVGADDSFFDLGGDSLSAMRA 2749 Query 970 LPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQ 1029 + L + + L A T LA T G R +VA QRPA +PLSFAQ Sbjct 2750 IATINATLDAHVGVRMLFEAPTIGQLASRIGT-----GGGRLDGVVAHQRPAVLPLSFAQ 2804 Query 1030 RRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQ 1089 RLWF+DQL P+ VYNMA ALRL G L+ ALGAA+ DVV RHESLRTVF AV+GVP+Q Sbjct 2805 SRLWFIDQLHGPSAVYNMAAALRLSGRLEATALGAALRDVVARHESLRTVFAAVEGVPQQ 2864 Query 1090 LVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLV 1149 +V+ RADL +DAT W RL+ AI + ARH+FDLATEIPLR LFR+ D+EHVLV Sbjct 2865 VVLAPERADLTWRAIDATGWSPARLEDAIRDTARHTFDLATEIPLRAELFRVGDEEHVLV 2924 Query 1150 AVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSD 1209 AV HHIAADG S+ PL DL+ AYASR AG APDWAPLPVQYVDYTLWQR GDL+D D Sbjct 2925 AVVHHIAADGGSLTPLVRDLAVAYASRVAGDAPDWAPLPVQYVDYTLWQRAHFGDLEDPD 2984 Query 1210 SPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHN 1269 SPIAAQLAYWE LAG+PERL LPT RPYP VAD RGAS V+WPA +QQ+VR +A HN Sbjct 2985 SPIAAQLAYWEQELAGLPERLELPTDRPYPLVADYRGASAPVEWPAELQQRVRAVATAHN 3044 Query 1270 ATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPS 1329 AT+FMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVLRV + DP+ Sbjct 3045 ATTFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVEVGADPT 3104 Query 1330 FAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGD 1389 AE+L QVR RSLAAYE+QDVPFE LV+RL PTR+L HHPL+QVMLAWQ+ L+LGD Sbjct 3105 VAEILAQVRRRSLAAYEHQDVPFEALVERLNPTRSLAHHPLVQVMLAWQNTGATDLSLGD 3164 Query 1390 LQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKV 1449 ++ TP+P+DTRTAR DL +SLAER++ +P GIGGAVE+RTDVF+ I+ LI RLR+V Sbjct 3165 VRVTPLPVDTRTARTDLAWSLAERWTPDGQPGGIGGAVEFRTDVFDPATIETLIGRLRRV 3224 Query 1450 LVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAE 1509 L A+ A P R +SSID L ER RLDE GNRA L P P SIP + A QVAR P A Sbjct 3225 LDAMTADPTRRLSSIDVLGAGERTRLDEIGNRATLFEPRVEPPSIPALFADQVARSPHAV 3284 Query 1510 AVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAY 1569 A+ S TYRELDE++NRLAHRL GAGPG+ VA+L ER A AVVA++AVLKTGAAY Sbjct 3285 ALTWQGRSTTYRELDESANRLAHRLIDEGAGPGQYVAVLMERSAQAVVAILAVLKTGAAY 3344 Query 1570 LPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA-AYPGTPPPMP 1628 LPIDPA P RV FML DA VAA++TA LRS L G + +IDV +A A A P + P Sbjct 3345 LPIDPAAPRNRVGFMLADARLVAAISTAALRSVLDGFGVAVIDVDEAAAHARPYSALPPT 3404 Query 1629 AAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARL-SAAQVWSQCHSYGFDASAWE 1687 AA ++AY++YTSGTTG PKGV +THRNV L S+ RL S VWSQCHS FD S WE Sbjct 3405 AAADIAYVIYTSGTTGTPKGVAVTHRNVAELLGSVRGRLTSTTGVWSQCHSLAFDFSVWE 3464 Query 1688 IWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPT-------QGLE 1740 I+GALL GGRL++VP+ V SP D LL+ E VSVL+QTP+A L + + L Sbjct 3465 IFGALLHGGRLLVVPDDVVRSPEDLCDLLIDEDVSVLSQTPSAFFALQSADASRSGRRLS 3524 Query 1741 SVALVVAGEACPAALVDRWAPGR----VMLNAYGPTETTICAAISAPLRP---GSGMPPI 1793 +V GEA + +W ++N YG TETT+ A+ + G G PI Sbjct 3525 PHTVVFGGEALVPQRLGKWVHNHPRHPRLVNMYGITETTVHASFREIVEADIDGHG-SPI 3583 Query 1794 GVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGAR 1853 G P++ FVLD+WLRPVPAGV GELY+AGAGV GY RAGLTASRFVACPF G GAR Sbjct 3584 GKPLAHLGFFVLDAWLRPVPAGVLGELYVAGAGVAAGYLGRAGLTASRFVACPFAGGGAR 3643 Query 1854 MYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRP 1913 MYRTGD+VCW DGQL+++GR DDQVK+RGYRIELGE+ +A+ EL GVGQA VIAREDRP Sbjct 3644 MYRTGDVVCWGHDGQLQYVGRADDQVKVRGYRIELGEIQSAITELEGVGQAAVIAREDRP 3703 Query 1914 GDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPA 1973 G+KRLVGY T G DPA +RAQLA+RLP Y+VPAAVV I+ALPLT NGKLD RALPA Sbjct 3704 GEKRLVGYVT----GTADPAEVRAQLAERLPAYMVPAAVVAIEALPLTPNGKLDARALPA 3759 Query 1974 PEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTL 2033 P+Y + Y AP VE+T+A I+A VLG++RVG+DDSFF+LGGDSL+AMR++A +NT L Sbjct 3760 PDYHGIDQYSAPTTAVERTMADIYAHVLGVDRVGIDDSFFDLGGDSLSAMRLVAEVNTNL 3819 Query 2034 NADLPVRALLHASSTRGLSQLLGR----------DARPTSDPR---------LVSVHGDN 2074 + L VRAL A + R L+ LG ARP P + +HG + Sbjct 3820 DVHLGVRALFEAPTIRRLAARLGDGGGDRLPLVAGARPEVVPLSFAQSRLWFIGQLHGPS 3879 Query 2075 PTEVHASDLTLDRFIDADTLATAV-NLPGPSPELRTVLLTGATGFLGRYLVLEL 2127 P A L L +D D A+ ++ LRT L A G + + LV+E+ Sbjct 3880 PVHNMAMALRLHGRLDGDAFGAALADVVARHESLRT--LFPAHGGIPQQLVVEV 3931 Score = 828 bits (2139), Expect = 0.0, Method: Compositional matrix adjust. Identities = 531/1054 (51%), Positives = 656/1054 (63%), Gaps = 73/1054 (6%) Query 1023 IPLSFAQRRLWF-LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 +PL+ Q+ L F Q A VY + + + LRG LD++ L AV V+ RH +L F Sbjct 1780 LPLTPLQQGLLFHATATQGAADVYAVQLTITLRGALDSQRLHRAVHTVITRHPNLAARFD 1839 Query 1082 AVDGVPRQLV----------IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATE 1131 + G P Q+V +E R D+ + A A+R+ AAR L E Sbjct 1840 SEFGDPLQIVPAAPDLAWQYVEIRDGDVEERVYQLCA--AERV------AAR---SLGEE 1888 Query 1132 IPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQY 1191 P RT L R A DE+ V HHI DGWS+ L ++ A Y R P AP Y Sbjct 1889 PPFRTALIRTAGDEYRFVLTVHHIVMDGWSLPVLLREIFACY---YGSRLPAVAP----Y 1941 Query 1192 VDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPE-RLRLPTARPYPPVADQRGASLV 1250 + W L D D P AA+LA W AL G L P R + G V Sbjct 1942 RSFVTW-------LADRDLP-AARLA-WREALDGFDTPTLVGPAGR------GELGPRGV 1986 Query 1251 VDWPASVQQQ--VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PA 1306 + S + + +AR T V+ A LL +G DVA G ++GR P Sbjct 1987 AELHLSAETTCALSELARSCRTTVNTVLQGAWAQLLMLQTGQRDVAFGTAVSGRPADLPG 2046 Query 1307 LDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT 1366 +++VG +NT+ +R + + AELL Q++ E+Q + + R Sbjct 2047 AESMVGLLINTVPVRARVTAITTVAELLNQLQRAHNDTLEHQHLALNEI------HRITG 2100 Query 1367 HHPLIQVMLAWQDNPVGQLNL---GDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGI 1423 H L +L +++ PV L GDL AT T+ + L+ + G E + Sbjct 2101 HDQLFDSLLVYENYPVDAATLSAAGDLTATAF-----TSHEYNHYPLSLQAVPGDE---L 2152 Query 1424 GGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAV 1483 VE+ DVF+A AID L RLR++LVA+AA P R V+++D LD TERA L WGNRA Sbjct 2153 SLRVEFDADVFDAAAIDKLTTRLRRLLVAMAADPARPVAALDVLDDTERAELARWGNRAA 2212 Query 1484 LTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGE 1543 L+ PA S+P++ AAQV R+P A AV SMTYRELDEASNRLAH L G G G+ Sbjct 2213 LSGPAGAAASLPELFAAQVTRVPGAVAVTFEGRSMTYRELDEASNRLAHLLLDQGVGAGD 2272 Query 1544 CVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRL 1603 VALLF R A +VAM+AVLK GAAYLPIDPA P R+ FM+ DA P AA+ T LRSRL Sbjct 2273 VVALLFPRSAEVIVAMLAVLKAGAAYLPIDPALPETRIGFMIDDAAPTAAIGTTELRSRL 2332 Query 1604 AGHDLPIIDVVDALAA-YPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS 1662 AG LP+I+V +A +P P PAA N+AY++YTSGTTG PKGV +THRNVT+L + Sbjct 2333 AGFALPVIEVGGTVAPDHPNAALPAPAAANVAYVIYTSGTTGVPKGVAVTHRNVTQLLPA 2392 Query 1663 LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 L A L AA VWSQCHSYGFD S EIWGAL GGGRLVIVPESV SP++ H LL+AE VS Sbjct 2393 LHAALPAAGVWSQCHSYGFDVSIQEIWGALAGGGRLVIVPESVTRSPDELHALLIAERVS 2452 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VL+ TP+A+A L Q L++ AL++ GE CP AL DRWAP RVM+NAYGPTETT+ A +SA Sbjct 2453 VLSHTPSALAALSPQHLDT-ALIIGGEPCPPALADRWAPRRVMINAYGPTETTVDAVLSA 2511 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PL G G PP+G PVSGAALFVLD WLRPVPAGV GELY+AGAGV VGY RRAGLTASRF Sbjct 2512 PLAAGGGAPPLGSPVSGAALFVLDGWLRPVPAGVIGELYVAGAGVAVGYARRAGLTASRF 2571 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 VACPFGG GARMYRTGDLV W DG+L ++GR D+QVKIRG+RIELGE+ +ALAEL GVG Sbjct 2572 VACPFGGVGARMYRTGDLVRWAPDGRLHYVGRADEQVKIRGHRIELGEIRSALAELDGVG 2631 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 Q VVIAREDRPG KR+V Y T G + A +R +LA RLP Y+VPAAV+ I+A+PLT Sbjct 2632 QTVVIAREDRPGQKRIVAYLT----GTAEAADVRDRLAARLPAYMVPAAVIAIEAVPLTP 2687 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAPE+ YRAP+G VE+ +AGI+A VLGLERVG DDSFF+LGGDSL+A Sbjct 2688 NGKLDARALPAPEH-TAGAYRAPSGAVEEILAGIYADVLGLERVGADDSFFDLGGDSLSA 2746 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLG 2056 MR IA IN TL+A + VR L A + L+ +G Sbjct 2747 MRAIATINATLDAHVGVRMLFEAPTIGQLASRIG 2780 Score = 340 bits (872), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 185/314 (59%), Positives = 223/314 (72%), Gaps = 23/314 (7%) Query 1804 VLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCW 1863 +LD WLRPVP GV GELY+AGAGVGVGY RAGL+ASRFVACPFG G RMYRTGDLV W Sbjct 1 MLDQWLRPVPIGVVGELYVAGAGVGVGYLGRAGLSASRFVACPFGAPGQRMYRTGDLVRW 60 Query 1864 RADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYAT 1923 ADGQL + GR D+QVK+RGYRIELGE+ TALAEL GV +A V+ REDR GDKR+VGY T Sbjct 61 GADGQLRYFGRADEQVKVRGYRIELGEIRTALAELDGVERAAVLVREDRVGDKRVVGYVT 120 Query 1924 EIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYR 1983 GA DPA +RA+L QRLP Y+VPAAVVV+DALP+T+NGKLD RALPAPEY +GYR Sbjct 121 ----GAADPADIRARLGQRLPTYMVPAAVVVLDALPVTLNGKLDTRALPAPEYQGGHGYR 176 Query 1984 APAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALL 2043 AP +E+ +AGIFARVL ++RVG+DDSFF LGGDSL+AMR+++AINT L+A L VR L Sbjct 177 APETAIEEILAGIFARVLNVDRVGIDDSFFHLGGDSLSAMRLVSAINTGLDAHLGVRILF 236 Query 2044 HASSTRGLSQL----LGRDAR--PTSDPRLV-------------SVHGDNPTEVHASDLT 2084 A + L+ +GR R PT P L+ G +P A L Sbjct 237 EAPTVAQLAPRVEAGVGRADRLAPTERPALLPLSFAQSRLWFIDQFQGPSPVYNMAVALK 296 Query 2085 LDRFIDADTLATAV 2098 L+ ++ D + A+ Sbjct 297 LNGPVNTDAMGAAL 310 Score = 98.6 bits (244), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 119/427 (28%), Positives = 187/427 (44%), Gaps = 54/427 (12%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A AY++ TSGTTG PK V ++H ++ ++ G G QC L D SV E Sbjct 874 ADNIAYVIYTSGTTGTPKGVAVTHHNVTQLLQSVDAQLGLG--QVWSQCHSLAFDFSVWE 931 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 +FG G RLV DL AL L+A ++ + +L +DG ++++ Sbjct 932 LFGSLLRGGRLVVVPDQVVRSPEDLHAL---LIAERVNVLSQTPSAAAVLPSDG--LESV 986 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF-LPIVCDQTTM 746 +++GGE +D+W + G +++ YGPTE T+ A +P+ ++ Sbjct 987 A------LIVGGEPCPLEVMDRW-----APGRVMVNQYGPTETTMYAAMTVPLTAGLDSV 1035 Query 747 -------DGALLRLG---RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAA-- 794 AL L RP+ P V GE+ I G VA GYLG G A Sbjct 1036 PIGSPVPGAALFVLDHWLRPVPPGVV----GELYIAGRGVATGYLGRAGLTASRFVACPF 1091 Query 795 DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV- 853 GS R + TGD V A+ + GR D +KI G R+++ E+ + E + AV Sbjct 1092 GGSGARMYRTGDLVRWGADAQLDYLGRADEQIKIRGYRIELGEIHSVLTELEGIEQAAVI 1151 Query 854 --ELHSGSLG-VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKI 910 E H ++ V + + E + A R+ +V VV + +P NGK+ Sbjct 1152 AREDHPAAVRLVGYVTGTADPSEVRSQLAERLPPYMVPAA-----VVTLDALPLTVNGKL 1206 Query 911 DSDNLPRLPQWSAAGLNTAETGQRAAG--LSQIWSRQLG-RAIGPDSSLLGEGIGSLDLI 967 D+ LP P + G+N A L+ I+++ LG +G D S G S+ + Sbjct 1207 DTRALP-APDY---GINEYRAPADAIEEILAGIYAQVLGLERVGIDDSFFDLGGDSILSM 1262 Query 968 RILPETR 974 +++ R Sbjct 1263 QVVARAR 1269 >gi|254822780|ref|ZP_05227781.1| syringomycin synthetase [Mycobacterium intracellulare ATCC 13950] Length=2767 Score = 2023 bits (5242), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1153/2098 (55%), Positives = 1395/2098 (67%), Gaps = 109/2098 (5%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEIS 520 LV+RGA PG + + + I ++A G Y + D A ++ Sbjct 719 LVERGARPGRCVAVLMERSAPAIVAIVAVLKTGAAYLPIDPAMPDTRVAFMLTDAAPIVA 778 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 + T + + DG V+D + L D+ + AY++ T Sbjct 779 LTTAELRDRLDGFDGAVIDADDPAVHTRPATALPPPADDNI-------------AYVIYT 825 Query 581 SGTTGQPKLVRISHGS----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAA 636 SGTTG PK V ++H + LA D + A W QC L D SV EIFG Sbjct 826 SGTTGTPKGVAVTHHNVTHLLASLHDRPAPAGVWS------QCHSLAFDFSVWEIFGALL 879 Query 637 CGA-------RLVRSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIG 688 G +VRS DL AL L+A +++ P+A L DG + Sbjct 880 GGGRLLVVPDEVVRSPE----DLHAL---LIAENVSVLSQTPSAFSALQSLDG--ARSGP 930 Query 689 RSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDG 748 R +R ++ GGEA+ + KWL+S + +++ YG TE TV A++ IV + +D Sbjct 931 RLNVRALLFGGEALSPQRLAKWLDSHPHRP-RVINMYGITETTVHASYREIV--DSDIDT 987 Query 749 ALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--D 795 +G P+ F+ GE+ I G VA GY+G G A Sbjct 988 NASPIGMPLAHLGFFVLDAWLRPVPEGVTGELYIAGSGVAAGYVGRAGLTASRFVACPFG 1047 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL 855 + R + TGD V G + GR D VKI G R+++ E+ + E + AV Sbjct 1048 AAGARMYRTGDLVRWGPGGQLHYLGRADEQVKIRGYRIELGEIQSALTELDGIEQAAVVA 1107 Query 856 HSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID 911 G V + + E A A + +V V + V +P NGK+D Sbjct 1108 REDRPGDKRLVGYITGTADPVEVRARLAEHLPAYMVPATV-----LAVDAMPLTANGKLD 1162 Query 912 SDNLPRLPQWSAAGLNT----AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDL 966 + LP P S + A T L+ I++ LG +G D S G SL Sbjct 1163 TRALP-APDHSHRSQGSDHYRAPTTPVERALADIYTHVLGVENVGIDDSFFDLGGDSLSA 1221 Query 967 IRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLS 1026 +R++ E L L + L A T LA T PLVA +RP +PLS Sbjct 1222 MRLVAEVNTGLDVHLGVRALFEAPTIRRLAARLGTDGGARA-----PLVAGERPEMVPLS 1276 Query 1027 FAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGV 1086 FAQ RLWF+ QL P+PV+NMA+AL+L G LD EA GAA+ADV+ RHESLRT+FPA +G+ Sbjct 1277 FAQSRLWFMGQLHGPSPVHNMAIALQLHGRLDAEAFGAALADVMARHESLRTMFPAREGI 1336 Query 1087 PRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEH 1146 PRQLV++ AD G I DA W RL A+E H FDLATEIPLR LFR++DDEH Sbjct 1337 PRQLVVDVDDADCGWQISDARGWSTTRLGNAVETLVGHRFDLATEIPLRAMLFRVSDDEH 1396 Query 1147 VLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLD 1206 +LVAV HHIAADGWS+ PL DL AYASR AG APDWAPLPVQYVDYTLWQR G+L Sbjct 1397 LLVAVVHHIAADGWSLTPLVRDLGEAYASRSAGCAPDWAPLPVQYVDYTLWQRAQFGELQ 1456 Query 1207 DSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIAR 1266 D S IA Q+ YWE+ALAGMPERL LPT RPYP VAD RGAS+ VDW A +QQ+VR +A Sbjct 1457 DPHSLIAGQVRYWEHALAGMPERLELPTDRPYPLVADFRGASVAVDWSAELQQRVRAVAG 1516 Query 1267 QHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAG 1326 HNATSFMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVLRV+LAG Sbjct 1517 AHNATSFMVVQAALAVLLAKISASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDLAG 1576 Query 1327 DPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLN 1386 DP+ AE+L VRARSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ+ +L+ Sbjct 1577 DPTIAEVLAHVRARSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNTDSAELS 1636 Query 1387 LGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERL 1446 LGD++ TP+P+DTRTARMDL +SLAER+S P GIGGAVE+RTDVF+ I LIERL Sbjct 1637 LGDVRVTPLPVDTRTARMDLAWSLAERWSADGRPEGIGGAVEFRTDVFDTATIQRLIERL 1696 Query 1447 RKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIP 1506 ++VL A+ A P R +SSID L E ARLD GNRAVL P+ P+SIP++ A VAR P Sbjct 1697 QRVLEAMTADPARRLSSIDVLGPDEHARLDAIGNRAVLDGPSRPPMSIPEVFADHVARTP 1756 Query 1507 EAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTG 1566 +A AV G S TYRELD+++NRLAH L G GPG+CVALL ER A AVVA++AVLKTG Sbjct 1757 QAVAVTHGADSWTYRELDQSANRLAHLLVDHGCGPGQCVALLTERSARAVVAILAVLKTG 1816 Query 1567 AAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPP 1625 AAY+PIDP P R+ FML DA P A +TTA RSRL D+ +ID+ D A+ P T Sbjct 1817 AAYVPIDPGLPAARIDFMLADAAPAAVLTTAEHRSRLDDFDVLVIDIDDPAIQHRPTTAL 1876 Query 1626 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS---LPARLSAAQVWSQCHSYGFD 1682 P PA ++AY +YTSGTTG PKGV +TH N T+LFAS + A+VWS CHS FD Sbjct 1877 PAPAPHHIAYTIYTSGTTGVPKGVAVTHHNATQLFASLGAAGLPAAPARVWSHCHSLAFD 1936 Query 1683 ASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESV 1742 S WEI+GALL GGR+++VP+ V SP D H LLVAE V +LTQTP+ V ML T+GLES Sbjct 1937 FSVWEIFGALLHGGRVLVVPDEVVRSPKDLHALLVAERVDMLTQTPSEVTMLSTEGLESA 1996 Query 1743 ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAAL 1802 L VAGEACPA +V RWA GRVM+N YGPTE TI AA+SAPL PG PPIG PVSGAAL Sbjct 1997 VLAVAGEACPAEIVQRWASGRVMVNVYGPTEITIVAAVSAPLTPGPEAPPIGSPVSGAAL 2056 Query 1803 FVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVC 1862 FVLD L+PVPAGV GELY+AG GV GY R GLTASRFVACPFGG GARMYRTGDL Sbjct 2057 FVLDGCLQPVPAGVVGELYVAGGGVSTGYLGRPGLTASRFVACPFGGEGARMYRTGDLAS 2116 Query 1863 WRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYA 1922 W +DGQL ++GR D+QVKIRGYRIELGE+ ALA L GV QA+VIAREDRPGDKRLVGY Sbjct 2117 WGSDGQLRYVGRADEQVKIRGYRIELGEIQLALAALDGVEQALVIAREDRPGDKRLVGYI 2176 Query 1923 TEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGY 1982 T G +PA LR LA RLP Y+VPAAVVV+D LPLT GKLD RALPAP+Y + Y Sbjct 2177 T----GTANPAELRTLLADRLPAYMVPAAVVVLDRLPLTPAGKLDVRALPAPDYQGGDDY 2232 Query 1983 RAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRAL 2042 APA VE+ +A ++A+VLGLERVGV +SFF+LGGDSL+AMR++AAI L+ LPVRA+ Sbjct 2233 LAPATAVEEILAWLYAQVLGLERVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAV 2292 Query 2043 LHASSTRGLSQLLGR--DARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNL 2100 A S R LSQ L R DA SVHG + TEV+A DLTLD+FIDA TLA A +L Sbjct 2293 FEAPSVRSLSQQLNRDHDAGEGHQGDFASVHGRDATEVYACDLTLDKFIDAPTLAAAPSL 2352 Query 2101 PGPSPELRTVLLTGATGFLGRYLVLELLRRLDV-DGRLICLVRAESDEDARRRLEKTFD- 2158 PGPS E+RTVLLTGATGFLGRYLVL+ L RL++ DG+LICLVRA SDEDARRRL++TFD Sbjct 2353 PGPSAEVRTVLLTGATGFLGRYLVLQWLERLELADGKLICLVRATSDEDARRRLQRTFDP 2412 Query 2159 ---SGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA- 2214 +GDP L R+F ELAAD LEV+AGDK +LGLD+ W+RLA+TVDLIVDSAA+VN Sbjct 2413 PGFAGDPALRRYFDELAADHLEVIAGDKGRTNLGLDEQTWQRLADTVDLIVDSAAVVNGV 2472 Query 2215 FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRT 2274 PY ELF PNVAGTAELIR+ALTTKLKP+TYVSTA+VG IEP+AFTEDAD+RV P RT Sbjct 2473 LPYSELFAPNVAGTAELIRLALTTKLKPYTYVSTANVGDQIEPAAFTEDADVRVAGPIRT 2532 Query 2275 VDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVL 2334 +DG + GYG SKWAGEVLLREA+DLCALPV VFRC MILADT+YAGQLN+SD TR++ Sbjct 2533 IDGSYGNGYGNSKWAGEVLLREAHDLCALPVGVFRCDMILADTTYAGQLNLSDMFTRLLF 2592 Query 2335 SLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMN 2394 S++A+G+APRSFY+ D+ GNRQRAHFD LPV FVAE+I LGA+V S AGF TYHVMN Sbjct 2593 SVVASGVAPRSFYQLDARGNRQRAHFDALPVEFVAESITTLGAQVGRDSAAGFETYHVMN 2652 Query 2395 PHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNS 2454 PHDDGIGLDEYVDW+IEAGYPI R+DDF EWL R E ++ ALP+RQR SVL +L N+ Sbjct 2653 PHDDGIGLDEYVDWVIEAGYPIERVDDFGEWLHRMETAVHALPERQRHQSVLQLLQLRNA 2712 Query 2455 QRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 Q + P P RGC PT+RFRAAV+ AK+G D DIPH++A I+ YVT+L+LLGLL Sbjct 2713 QHVPPADPARGCLGPTERFRAAVQEAKIGPDN---DIPHITAAVIVKYVTDLRLLGLL 2767 Score = 1283 bits (3319), Expect = 0.0, Method: Compositional matrix adjust. Identities = 735/1332 (56%), Positives = 893/1332 (68%), Gaps = 62/1332 (4%) Query 813 EGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQR 868 +G+ + GR D VKI G R+++ E+ +AE V VAV + G V + + Sbjct 1 DGWLHYVGRADHQVKIRGHRIELGEIQSALAELDGVGRVAVIAREDTPGDKRLVGYITGT 60 Query 869 TREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNT 928 E A A R+ LV V V + +P PNGK+D+ LP P+++ Sbjct 61 ADPVELRARLADRLPAYLVPAAV-----VAIEALPLTPNGKLDTGALP-APEYTGGRYRA 114 Query 929 AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLI 987 T L+ I+++ LG +G D S G SL +R++ L L + L Sbjct 115 PATPTEEI-LAGIYAQVLGLERVGADDSFFDLGGDSLSAMRVIAAINSGLDAHLGVRTLF 173 Query 988 GADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNM 1047 A T LA R + +RPA +PLSFAQ RLWF+DQL P+PVYNM Sbjct 174 EAPTIGELA-----ARVSANGGRLAGVEPRERPAVVPLSFAQSRLWFIDQLHGPSPVYNM 228 Query 1048 AVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDAT 1107 A ALRL G LD ALGAA ADVV RHESLRTVF A +G+P+Q+V+ RAD+ +DAT Sbjct 229 AAALRLAGRLDAGALGAAFADVVARHESLRTVFAATEGIPQQVVLSPDRADVTWQTIDAT 288 Query 1108 AWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTA 1167 W RL+ AI +AARH+FDLATEIPLR LFR++DDEHVLVAV HHIAADGWS+ PL Sbjct 289 GWSPARLEGAIRDAARHTFDLATEIPLRAMLFRVSDDEHVLVAVVHHIAADGWSLTPLVR 348 Query 1168 DLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMP 1227 DL+ AYASR G AP WAPLPVQY+DYTLWQR GDL+D SPIAAQLAYWE ALAG+P Sbjct 349 DLALAYASRSVGDAPGWAPLPVQYIDYTLWQRAQFGDLEDPGSPIAAQLAYWEEALAGLP 408 Query 1228 ERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKL 1287 ERL LPT RPYP VAD RGAS+ VDWPA +QQ+VR +A HNATSFMVV A LAVLL+K+ Sbjct 409 ERLELPTDRPYPLVADFRGASVAVDWPAELQQRVRAVAGAHNATSFMVVQAALAVLLAKI 468 Query 1288 SGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYEN 1347 S S DVAVGFPIAGR DPALD++VGFFVNTLVLRV+LAGDP+ AE+L VRARSLAAYE+ Sbjct 469 SASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDLAGDPTIAEVLAHVRARSLAAYEH 528 Query 1348 QDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLV 1407 QDVPFEVLV+RL P R+L HHPL+QVMLAWQ++ ++LGD++ T +P+DTRTAR DL Sbjct 529 QDVPFEVLVERLNPARSLAHHPLVQVMLAWQNDEPTDVSLGDVRITALPVDTRTARTDLA 588 Query 1408 FSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDAL 1467 +SLAER+S PAGIGGAVE+RTDVF+ I LIERL++VL A+ A P R +SSID L Sbjct 589 WSLAERWSADGRPAGIGGAVEFRTDVFDTATIQSLIERLQRVLAAMTADPARRLSSIDVL 648 Query 1468 DGTERARLDEWGNRAVLTAP----APTPVSIPQMLAAQVARIPEAEAVCCGDASMTYREL 1523 E ARLD GNRA LT P A T SIP + AA VAR PEA A+ D SMTYRE Sbjct 649 GPDEHARLDAIGNRAALTRPPHASALTRASIPALFAAHVARTPEAVALSDRDRSMTYREF 708 Query 1524 DEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAF 1583 DE++NRLAH L GA PG CVA+L ER APA+VA+VAVLKTGAAYLPIDPA P RVAF Sbjct 709 DESTNRLAHLLVERGARPGRCVAVLMERSAPAIVAIVAVLKTGAAYLPIDPAMPDTRVAF 768 Query 1584 MLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGT 1642 ML DA P+ A+TTA LR RL G D +ID D A+ P T P PA N+AY++YTSGT Sbjct 769 MLTDAAPIVALTTAELRDRLDGFDGAVIDADDPAVHTRPATALPPPADDNIAYVIYTSGT 828 Query 1643 TGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVP 1702 TG PKGV +TH NVT L ASL R + A VWSQCHS FD S WEI+GALLGGGRL++VP Sbjct 829 TGTPKGVAVTHHNVTHLLASLHDRPAPAGVWSQCHSLAFDFSVWEIFGALLGGGRLLVVP 888 Query 1703 ESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQG-------LESVALVVAGEACPAAL 1755 + V SP D H LL+AE+VSVL+QTP+A + L + L AL+ GEA Sbjct 889 DEVVRSPEDLHALLIAENVSVLSQTPSAFSALQSLDGARSGPRLNVRALLFGGEALSPQR 948 Query 1756 VDRW---APGR-VMLNAYGPTETTICAAISAPLRP--GSGMPPIGVPVSGAALFVLDSWL 1809 + +W P R ++N YG TETT+ A+ + + PIG+P++ FVLD+WL Sbjct 949 LAKWLDSHPHRPRVINMYGITETTVHASYREIVDSDIDTNASPIGMPLAHLGFFVLDAWL 1008 Query 1810 RPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQL 1869 RPVP GV GELYIAG+GV GY RAGLTASRFVACPFG +GARMYRTGDLV W GQL Sbjct 1009 RPVPEGVTGELYIAGSGVAAGYVGRAGLTASRFVACPFGAAGARMYRTGDLVRWGPGGQL 1068 Query 1870 EFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGA 1929 +LGR D+QVKIRGYRIELGE+ +AL EL G+ QA V+AREDRPGDKRLVGY T G Sbjct 1069 HYLGRADEQVKIRGYRIELGEIQSALTELDGIEQAAVVAREDRPGDKRLVGYIT----GT 1124 Query 1930 VDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGD----TNGYRAP 1985 DP +RA+LA+ LP Y+VPA V+ +DA+PLT NGKLD RALPAP++ ++ YRAP Sbjct 1125 ADPVEVRARLAEHLPAYMVPATVLAVDAMPLTANGKLDTRALPAPDHSHRSQGSDHYRAP 1184 Query 1986 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHA 2045 PVE+ +A I+ VLG+E VG+DDSFF+LGGDSL+AMR++A +NT L+ L VRAL A Sbjct 1185 TTPVERALADIYTHVLGVENVGIDDSFFDLGGDSLSAMRLVAEVNTGLDVHLGVRALFEA 1244 Query 2046 SSTRGLSQLLGRDA----------RPTSDPR---------LVSVHGDNPTEVHASDLTLD 2086 + R L+ LG D RP P + +HG +P A L L Sbjct 1245 PTIRRLAARLGTDGGARAPLVAGERPEMVPLSFAQSRLWFMGQLHGPSPVHNMAIALQLH 1304 Query 2087 RFIDADTLATAV 2098 +DA+ A+ Sbjct 1305 GRLDAEAFGAAL 1316 >gi|254775687|ref|ZP_05217203.1| hypothetical protein MaviaA2_13615 [Mycobacterium avium subsp. avium ATCC 25291] Length=2527 Score = 2015 bits (5220), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1135/1978 (58%), Positives = 1370/1978 (70%), Gaps = 88/1978 (4%) Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAY-GWGAHDTVLQCAPLTSDISVEEI 631 AY++ TSGTTG PK V ++H ++A +++ + G G QC D+SV+EI Sbjct 600 NIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWS---QCHSYGFDVSVQEI 656 Query 632 FGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 +G A G LV T L L+A T+ L A+ A+ Sbjct 657 WGALAGGGGLVVVPESVTSSPDELHALLIAENVTV----------LSQTPSALAALSPRN 706 Query 692 LR-QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGAL 750 L +VIGGE + D+W + G ++++YGPTE TV A ++ Sbjct 707 LHVALVIGGEPCPAALADRW-----APGRVMINAYGPTETTVDA----VLSTPLAAGAGA 757 Query 751 LRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGS 797 LG P+ T+F+ GE+ I G VA GYLG G A G+ Sbjct 758 PPLGSPVAGATLFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPFGGA 817 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 R + TGD V D +G + R D VKI G R+++ E+ +AE V AV Sbjct 818 GARMYRTGDLVRWDRDGRLHYFARADQQVKIRGHRIELGEIHSALAELDGVEQAAV---- 873 Query 858 GSLGVWFKSQRTREGEQDAA---------AATRIRLV--LVSLGVSSFFVVGVPNIPRKP 906 ++ R GE+ AA R RL L + V + V+ + +P P Sbjct 874 -------IAREDRPGEKRIVGYLTGTADPAAIRARLAERLPAYMVPAA-VLAIEALPLTP 925 Query 907 NGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLD 965 NGK+D+ LP P++ A G A + ++ I+++ LG +G D S G SL Sbjct 926 NGKLDARALPA-PEY-AGGAYRAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGGDSLS 983 Query 966 LIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE--DRFRPLVAAQRPAAI 1023 +R++ L RLS+ L A T A LA A GE RF +VAA+RPA + Sbjct 984 AMRVIAAVNAGLDARLSVRVLFEAPTIAQLA-------ARLGEGGHRFAAVVAAERPAVV 1036 Query 1024 PLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAV 1083 PLSFAQ RLWF+ QL P+PVYNM ALRL G +D ALGAA+ DVV RHESLRTVF A Sbjct 1037 PLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVFAAT 1096 Query 1084 DGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIAD 1143 DG P Q+V+ RAD+G ++DA+ W R+ AI + ARH+FDLA EIPLR L R D Sbjct 1097 DGTPAQVVLPPDRADIGWQVIDASGWSPARVDDAIRDTARHTFDLAAEIPLRAVLLRCGD 1156 Query 1144 DEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILG 1203 +EH+LVAV HHIAADGWS+ PL DL+ AYASR AGR PDW PLPVQYVDYTLWQR G Sbjct 1157 EEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFG 1216 Query 1204 DLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRR 1263 DLDD S IA QL YWE+ALAGMPERL LPT RPYP VAD RGAS+ +DWPA +QQQ+ R Sbjct 1217 DLDDPHSLIAGQLRYWESALAGMPERLELPTDRPYPVVADFRGASVTIDWPAQLQQQISR 1276 Query 1264 IARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVN 1323 +A HNATSFMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVLRV+ Sbjct 1277 LAGAHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVD 1336 Query 1324 LAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVG 1383 ++GDP+ EL+ +VR RSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ+ Sbjct 1337 VSGDPTVGELVARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPT 1396 Query 1384 QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLI 1443 +L+LG ++ TP+P+DTRTARMDL +SLAER++ PAGIGGAVE+RTDVF+ ++ L Sbjct 1397 ELSLGQVRVTPLPVDTRTARMDLAWSLAERWTSDGSPAGIGGAVEFRTDVFDTATVEALT 1456 Query 1444 ERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVA 1503 +RLR+VL A+ A P R +SSID LD E ARLD GNRA LT P P SIP++ AA VA Sbjct 1457 QRLRRVLAAMTADPGRRLSSIDLLDPDEHARLDALGNRAALTRPQHPPTSIPEVFAAHVA 1516 Query 1504 RIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVL 1563 R P A AV CG S TYRELD ++NRLAH L GAGPG+CVALL ER A AV A++ VL Sbjct 1517 RTPHAVAVTCGRRSWTYRELDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILGVL 1576 Query 1564 KTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPG 1622 K GAAYLPIDP+ P R+ FML DA P A +T+ RL +D +IDV D ++ P Sbjct 1577 KAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPV 1636 Query 1623 TPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL-PARLSAA--QVWSQCHSY 1679 T PP PA N+AY++YTSGTTG P GV +THRN T+LFASL A L AA +VW QCHS Sbjct 1637 TAPPAPAPDNIAYLIYTSGTTGVPTGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSL 1696 Query 1680 GFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGL 1739 FD S WEI+GALL GGR+++VP+ V SP D H LLVAE V +LTQTP+ V +L GL Sbjct 1697 AFDFSVWEIFGALLNGGRVLVVPDDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDGL 1756 Query 1740 ESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSG 1799 ES L VAGEACP +VDRWAPGRVM+N YGPTETTI AA+SAPL PG PPIG PV G Sbjct 1757 ESTTLAVAGEACPVEVVDRWAPGRVMINVYGPTETTIVAAVSAPLTPGPEAPPIGAPVPG 1816 Query 1800 AALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGD 1859 AL VLD+ LRPVP GV GELY+AGAGV GY R GLTASRFVACPFGG+G RMYRTGD Sbjct 1817 TALRVLDAHLRPVPPGVVGELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGD 1876 Query 1860 LVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLV 1919 LV W ADGQL++LGR D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLV Sbjct 1877 LVRWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLV 1936 Query 1920 GYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDT 1979 GY T G D A LR LA+RLPGY+VPAAV+++DALPLT +GKLD ALPAP+Y Sbjct 1937 GYVT----GTADLAQLRTALAERLPGYMVPAAVLMLDALPLTPSGKLDTGALPAPDYQGP 1992 Query 1980 NGYRAPAGPVEKTVAGIFARVLGL-ERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLP 2038 GY APAG VE+ +A ++A+VLGL RVGV +SFF+LGGDSL+AMR++AAI L+ LP Sbjct 1993 EGYLAPAGAVEEILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLP 2052 Query 2039 VRALLHASSTRGLSQLLGRDARPTSDPR--LVSVHGDNPTEVHASDLTLDRFIDADTLAT 2096 VRA+ A S R LSQ L D R SVHG + TEV+ASDLTLD+FIDA TL+ Sbjct 2053 VRAVFEAPSVRSLSQRLNADPAVAQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSA 2112 Query 2097 AVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV-DGRLICLVRAESDEDARRRLEK 2155 A LPGP E+RTVLLTGATGF+GRYLVL+ L RL++ DG+LICLVRA SD+DARRRLE+ Sbjct 2113 APALPGPGAEVRTVLLTGATGFVGRYLVLQWLERLELADGKLICLVRAASDDDARRRLER 2172 Query 2156 TFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA- 2214 TFDSGDP LLR+F ELAAD LEV+AGDK +LGLD W+RLA+TVDLIVD+AA+VN Sbjct 2173 TFDSGDPALLRYFHELAADHLEVIAGDKGRANLGLDDRTWQRLADTVDLIVDAAAVVNGV 2232 Query 2215 FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRT 2274 PY ELFGPNVAGTAELIR+AL+T+LKP++YVSTA+VG IEPSAFTEDADIRV P RT Sbjct 2233 LPYQELFGPNVAGTAELIRLALSTRLKPYSYVSTANVGDQIEPSAFTEDADIRVAGPIRT 2292 Query 2275 VDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVL 2334 +DGG+ GYG SKWAGEVLLREA+DLC LPV+VFRC MILADTSYAGQLN+SD TR++ Sbjct 2293 IDGGYGNGYGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTSYAGQLNLSDMFTRLLF 2352 Query 2335 SLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMN 2394 S++A+G+APRSFY D+ GNRQRAHFD LPV FVAEAIA LGA+V + FATYHVMN Sbjct 2353 SVVASGVAPRSFYRLDAHGNRQRAHFDALPVEFVAEAIATLGAQVGRDAGTAFATYHVMN 2412 Query 2395 PHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNS 2454 PHDDGIGLDEYVDWLIEAGYPI R+DDF +WL R E +L ALP+RQR SVL +L N+ Sbjct 2413 PHDDGIGLDEYVDWLIEAGYPIERVDDFDQWLHRMETALHALPERQRHQSVLQLLALRNA 2472 Query 2455 QRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 + + P P RGC PT+RFRAAV+ AK+G+D DIPH++AP I+ YVT+LQLLGLL Sbjct 2473 RHVPPADPARGCLGPTERFRAAVQEAKIGADN---DIPHITAPVIVKYVTDLQLLGLL 2527 Score = 812 bits (2097), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/1026 (51%), Positives = 636/1026 (62%), Gaps = 63/1026 (6%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV-----IEARRAD 1098 VY + +++ LRG LD L A+ VV RH +L F G P Q++ I R + Sbjct 43 VYAVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQIIPAEPEIAWRYLE 102 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L VD ++L++ + +L P L R AD EH V HH+ D Sbjct 103 LDASDVD------EQLEQLSADERAAVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMD 156 Query 1159 GWSVAPLTADLSAAY-ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLA 1217 GWS+ L ++ A Y +R P P Y + W L D P A A Sbjct 157 GWSLPVLLQEIFACYYGARL--------PAPAPYRGFVTW-------LAARDVP--AARA 199 Query 1218 YWENALAGMPERLRLPTARPYPPVADQRGASLVVDW--PASVQQQVRRIARQHNATSFMV 1275 W L G PT P AD G V + A V +AR+ T V Sbjct 200 AWRAVLDG----FDTPTLVA-PRGADAPGRRGVASFRMAAETTSAVSELARRRRTTVNTV 254 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGDPSFAEL 1333 + A A LL L+G DVA G ++GR P +++VG +NT+ +R A + A+L Sbjct 255 LQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRARAAAATTIADL 314 Query 1334 LGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLG---DL 1390 L Q++ E+Q + + R L +L +++ P+ L DL Sbjct 315 LDQLQCAHNDTVEHQHLGLNEI------HRVTGQDQLFDTLLVYENYPIDTAALSAADDL 368 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 AT + L+ + G E +G +E+ TDVF+ AID L +RLR++L Sbjct 369 TATEFSCHDYNH-----YPLSLQVVPGDE---LGLRLEFDTDVFDPAAIDTLADRLRRLL 420 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 A+ A P+R + S+D LD TE RL WGNR L+ PA P S+P++ AQVA P A A Sbjct 421 AAMPADPDRPLRSLDLLDSTEHTRLQRWGNRPALSRPATGP-SLPELFTAQVANAPHAVA 479 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 + C SMTYRELDEAS RLAH LAG GA PG VALLF R A A+VAM+AVLKTGAAYL Sbjct 480 LRCAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYL 539 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAA 1630 PIDPA P R+ FMLGDA PV AV+TAGLR+RL LP++DV A A PG P P PA Sbjct 540 PIDPALPATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDVA-ATGAQPGGPLPPPAP 598 Query 1631 VNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 N+AY+LYTSGTTG PKGV +THRNV +L SL A L VWSQCHSYGFD S EIWG Sbjct 599 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWSQCHSYGFDVSVQEIWG 658 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 AL GGG LV+VPESV +SP++ H LL+AE+V+VL+QTP+A+A L + L VALV+ GE Sbjct 659 ALAGGGGLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLH-VALVIGGEP 717 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CPAAL DRWAPGRVM+NAYGPTETT+ A +S PL G+G PP+G PV+GA LFVLD WLR Sbjct 718 CPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDGWLR 777 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 PVPAGV GELYIAGAGV GY RAGLTA+RFVACPFGG+GARMYRTGDLV W DG+L Sbjct 778 PVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGRLH 837 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 + R D QVKIRG+RIELGE+ +ALAEL GV QA VIAREDRPG+KR+VGY T G Sbjct 838 YFARADQQVKIRGHRIELGEIHSALAELDGVEQAAVIAREDRPGEKRIVGYLT----GTA 893 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DPA +RA+LA+RLP Y+VPAAV+ I+ALPLT NGKLD RALPAPEY YRAP+ P E Sbjct 894 DPAAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAG-GAYRAPSTPTE 952 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 + +AGI+ +VLGL RVGVDDSFF+LGGDSL+AMRVIAA+N L+A L VR L A + Sbjct 953 EIIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQ 1012 Query 2051 LSQLLG 2056 L+ LG Sbjct 1013 LAARLG 1018 >gi|118465061|ref|YP_882421.1| syringomycin synthetase [Mycobacterium avium 104] gi|118166348|gb|ABK67245.1| syringomycin synthetase [Mycobacterium avium 104] Length=6212 Score = 2006 bits (5196), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1136/1976 (58%), Positives = 1365/1976 (70%), Gaps = 66/1976 (3%) Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVL-QCAPLTSDISVEEI 631 AY++ TSGTTG PK V ++H + ++ A A V QC L D SV EI Sbjct 4267 NIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEI 4326 Query 632 FGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIG 688 FG G R++ DL AL+ D + P+A L AD + Sbjct 4327 FGALLNGGRVLVVPDDVVRSPEDLCALLID--EHVDVLSQTPSAFDALQRAD-----SAR 4379 Query 689 RSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDG 748 R + ++ GGEA+ + WL+ ++ L++ YG TE TV A+F IV +DG Sbjct 4380 RLNPQTVIFGGEALIPHRLGGWLDGHPARP-RLINMYGITETTVHASFREIV--DGDIDG 4436 Query 749 ALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--D 795 + +G P+ F+ GE+ I G VA GYLG G A Sbjct 4437 NVSPIGMPLAHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFG 4496 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL 855 G+ R + TGD +G + GR D VKI G R+++ E+ +AE V V Sbjct 4497 GAGERMYRTGDLARWGTDGQLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATVIA 4556 Query 856 HSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID 911 G V + + + A A R+ LV V V + +P PNGK+D Sbjct 4557 REDRPGDKRLVGYVTGTADPAQLRTALAERLPAYLVPAAV-----VAIDAMPLTPNGKLD 4611 Query 912 SDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG----RAIGPDSSLLGEGIGSLDLI 967 + LP P + A A L+ I++ L R +G D S G SL + Sbjct 4612 TGALPA-PDYHGADQYHAPASAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAM 4670 Query 968 RILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGED--RFRPLVAAQRPAAIPL 1025 R++ E L L + L A T LA A G D PLVAA+RPA +PL Sbjct 4671 RLVAEVNSRLDVHLGVRALFEAPTIRRLA-------ARLGADGSARAPLVAAERPAVVPL 4723 Query 1026 SFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDG 1085 SFAQ RLWF+ QL P+PV+NMA+AL+L G LD A GAA+ADVVGRHESLRT+FPA +G Sbjct 4724 SFAQSRLWFIGQLHGPSPVHNMAIALQLHGRLDAAAFGAALADVVGRHESLRTLFPAHEG 4783 Query 1086 VPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDE 1145 +P+QLVIE AD+G ++DA+ W RL I + ARH+FDLA EIPLR L R D+E Sbjct 4784 IPQQLVIEVDEADIGWQVIDASGWSPARLDDVIRDTARHTFDLAAEIPLRAVLLRCGDEE 4843 Query 1146 HVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDL 1205 H+LVAV HHIAADGWS+ PL DL+ AYASR AGR PDW PLPVQYVDYTLWQR GDL Sbjct 4844 HLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDL 4903 Query 1206 DDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIA 1265 DD S IA QL YWE+ALAGMPERL LPT RPYP VAD RGAS+ V+WPA +QQQ+ R+A Sbjct 4904 DDPHSLIAGQLRYWESALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLA 4963 Query 1266 RQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLA 1325 HNATSFMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVLRV+++ Sbjct 4964 GAHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDVS 5023 Query 1326 GDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQL 1385 GDP+ AELL +VR RSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ+ +L Sbjct 5024 GDPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPTEL 5083 Query 1386 NLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIER 1445 +LG ++ P+P+DTRTARMDL +SLAER++ PAGIGGAVE+RTDVF+ ++ L +R Sbjct 5084 SLGQVRVIPLPVDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRTDVFDTATVEALTQR 5143 Query 1446 LRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARI 1505 LR+VL A+ A P R +SSID LD E ARLD GNRAVLT P P SIP++ AA VAR Sbjct 5144 LRRVLAAMTADPGRRLSSIDLLDPAEHARLDALGNRAVLTRPQHPPTSIPEVFAAHVART 5203 Query 1506 PEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKT 1565 P A AV CG S TYRELD ++NRLAH L GAGPG+CVALL ER A AV A++ VLK Sbjct 5204 PHAVAVTCGRRSWTYRELDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILGVLKA 5263 Query 1566 GAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTP 1624 GAAYLPIDP+ P R+ FML DA P A +T+ RL +D +IDV D ++ P T Sbjct 5264 GAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTA 5323 Query 1625 PPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL-PARLSAA--QVWSQCHSYGF 1681 PP PA N+AY++YTSGTTG PKGV +THRN T+LFASL A L AA +VW QCHS F Sbjct 5324 PPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAF 5383 Query 1682 DASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLES 1741 D S WEI+GALL GGR+++VP+ V SP D H LLVAE V +LTQTP+ V +L GLES Sbjct 5384 DFSVWEIFGALLNGGRVLVVPDDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDGLES 5443 Query 1742 VALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAA 1801 L VAGEACP +VDRWAPGRVM+N YGPTETTI AA+SAPL PG PPIG PV G A Sbjct 5444 TTLAVAGEACPVEVVDRWAPGRVMINVYGPTETTIVAAVSAPLTPGPEAPPIGAPVPGTA 5503 Query 1802 LFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLV 1861 L VLD+ LRPVP GV GELY+AGAGV GY R GLTASRFVACPFGG+G RMYRTGDLV Sbjct 5504 LRVLDAHLRPVPPGVVGELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGDLV 5563 Query 1862 CWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGY 1921 W ADGQL++LGR D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLVGY Sbjct 5564 RWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGY 5623 Query 1922 ATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG 1981 T G D A LR LA+RLPGY+VPAAV+++DALPLT +GKLD ALPAP+Y G Sbjct 5624 VT----GTADLAQLRTALAERLPGYMVPAAVLMLDALPLTPSGKLDTGALPAPDYQGPEG 5679 Query 1982 YRAPAGPVEKTVAGIFARVLGL-ERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Y APAG VE+ +A ++A+VLGL RVGV +SFF+LGGDSL+AMR++AAI L+ LPVR Sbjct 5680 YLAPAGAVEEILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLPVR 5739 Query 2041 ALLHASSTRGLSQLLGRDARPTSDPR--LVSVHGDNPTEVHASDLTLDRFIDADTLATAV 2098 A+ A S R LSQ L D R SVHG + TEV+ASDLTLD+FIDA TL+ A Sbjct 5740 AVFEAPSVRSLSQRLNADPAVAQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSAAP 5799 Query 2099 NLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV-DGRLICLVRAESDEDARRRLEKTF 2157 LPGP E+RTVLLTGATGFLGRYLVL+ L RL++ DG+LICLVRA SD+DARRRLE+TF Sbjct 5800 ALPGPGAEVRTVLLTGATGFLGRYLVLQWLERLELADGKLICLVRAASDDDARRRLERTF 5859 Query 2158 DSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA-FP 2216 DSGDP LLR+F ELAAD LEV+AGDK +LGLD W+RLA+TVDLIVD+AA+VN P Sbjct 5860 DSGDPALLRYFHELAADHLEVIAGDKGRANLGLDDRTWQRLADTVDLIVDAAAVVNGVLP 5919 Query 2217 YHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVD 2276 Y ELFGPNVAGTAELIR+AL+T+LKP++YVSTA+VG IEPSAFTEDADIRV P RT+D Sbjct 5920 YQELFGPNVAGTAELIRLALSTRLKPYSYVSTANVGDQIEPSAFTEDADIRVAGPIRTID 5979 Query 2277 GGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSL 2336 GG+ GYG SKWAGEVLLREA+DLC LPV+VFRC MILADTSYAGQLN+ D TR++ S+ Sbjct 5980 GGYGNGYGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTSYAGQLNLPDMFTRLLFSV 6039 Query 2337 MATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPH 2396 +A+G+APRSFY D+ GNRQRAHFD LPV FVAEAIA LGA+V + GFATYHVMNPH Sbjct 6040 VASGVAPRSFYRLDAHGNRQRAHFDALPVEFVAEAIATLGAQVGRDAGTGFATYHVMNPH 6099 Query 2397 DDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQR 2456 DDGIGLDEYVDWLI+AGYPI R+DDF +WL R E +L AL +RQR SVL +L N++ Sbjct 6100 DDGIGLDEYVDWLIDAGYPIERVDDFDQWLHRMETALHALSERQRHQSVLQLLALRNARH 6159 Query 2457 LQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 + P P RGC PT+RFRAAV+ AK+G+D DIPH++AP I+ YVT+LQLLGLL Sbjct 6160 VPPADPARGCLGPTERFRAAVQEAKIGADN---DIPHITAPVIVKYVTDLQLLGLL 6212 Score = 1362 bits (3525), Expect = 0.0, Method: Compositional matrix adjust. Identities = 791/1481 (54%), Positives = 959/1481 (65%), Gaps = 63/1481 (4%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A A+++ TSGTTG+PK V +SH ++ ++ G QC L D SV E Sbjct 684 AGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTGITLGPDQVWSQCHSLAFDFSVWE 743 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 I+ G RLV + A DL L+ + R T + P+A L D++ Sbjct 744 IWAALLHGGRLVVVSDAVARSPDDLRRLL--IRERVTVLTQTPSAAGALSPQGLDSV--- 798 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTTM 746 +VIG E VD+W +++ YGPTE T+ V+ P+ Sbjct 799 ------ALVIGAEPCPPELVDRWAPDRV-----MINVYGPTETTMWVSHSRPLAAGSGAP 847 Query 747 DGALLRLGRPILPNTVF-----LAFGEVVIVGDLVADGYLGIDGDGFGTVTAAD------ 795 +G P+ + F L V + G+L G G A Sbjct 848 P-----IGSPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVACP 902 Query 796 --GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV 853 G+ R + TGD V A+G + GR D VKI G R+++ E+ + + V AV Sbjct 903 FGGTGTRMYRTGDLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSALTDLDGVEQAAV 962 Query 854 ELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKI 910 S G +R A ++R L V+ + +P NGK+ Sbjct 963 IAREDSPG----HKRLVAYLTGTADPAQVRTQLADRLPGYMLPSAVLALDALPLTVNGKL 1018 Query 911 DSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRI 969 D+ LP P+ A A L+ +++R LG +G D S G SL +R+ Sbjct 1019 DTRALPA-PELRAENRYRAPQNPTEESLADVYARLLGLERVGVDDSFFELGGDSLSAMRL 1077 Query 970 LPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQ 1029 + L L++ L A T A LA P G R LVAA+RPA +PLSFAQ Sbjct 1078 ITAVNAELDADLTVRALFEAPTVAQLA-----PRVAAGTGRAGRLVAAERPAVLPLSFAQ 1132 Query 1030 RRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQ 1089 RLWF+DQL P+PVYNMAVAL LRG LDT+ALGAA+ DVV RHESLRT+FPA DG PRQ Sbjct 1133 SRLWFIDQLHGPSPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRTLFPAPDGAPRQ 1192 Query 1090 LVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLV 1149 +V+EA RA++ +VDA WPA L A EAAR++FDLATEIPLR WLFR DEHVLV Sbjct 1193 VVLEAERAEVDWQVVDAARWPASWLAEATHEAARYTFDLATEIPLRAWLFRRNHDEHVLV 1252 Query 1150 AVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSD 1209 AV HHIAADGWS+ PL DL AAYASRC GR PDWAPLPVQY DYTLWQR GDLDD D Sbjct 1253 AVVHHIAADGWSLTPLVRDLGAAYASRCRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPD 1312 Query 1210 SPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHN 1269 SPIA QL YW+ ALAGMPER+ LPT RPYP VAD GAS+ V WPA +QQ + ++AR HN Sbjct 1313 SPIATQLQYWQRALAGMPERVALPTDRPYPLVADHLGASVQVHWPAELQQHIAQLARTHN 1372 Query 1270 ATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPS 1329 ATSFMVV A LAVLLS LS +PDVAVGFPIAGR DPALD++VGFFVNTLVLRV+LA DPS Sbjct 1373 ATSFMVVQAALAVLLSTLSANPDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDLADDPS 1432 Query 1330 FAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGD 1389 AELLGQVR RSL AYENQDVPFE+LV+RL PTR+L HHPL+QVMLAWQ+N ++LGD Sbjct 1433 IAELLGQVRHRSLQAYENQDVPFELLVERLNPTRSLAHHPLVQVMLAWQNNDPVDVSLGD 1492 Query 1390 LQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKV 1449 + TPMP++ + ARMDLV+SLAER++ P GI G VE+RTDVF+A +I+ L+ RL++V Sbjct 1493 VHVTPMPLENQVARMDLVWSLAERWTADGRPDGIDGTVEFRTDVFDAASIETLVRRLQRV 1552 Query 1450 LVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAE 1509 L+A+ A P R VSSID LD E A LD GNRA LT PA VSI Q+ AAQVAR PEA Sbjct 1553 LLAMTADPARPVSSIDILDEPEYAHLDALGNRAALTRPATGWVSISQLFAAQVARTPEAV 1612 Query 1510 AVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAY 1569 A+ CG+ S TYRELD ++NRLA LAG GA PGE VA+L R A AVV+++AVLKTGAAY Sbjct 1613 AISCGERSWTYRELDSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSILAVLKTGAAY 1672 Query 1570 LPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYP---GTPPP 1626 +PIDP P R+ FML DAVPV VTTA LR+ AG ++ + D P G P Sbjct 1673 VPIDPGLPSARIDFMLADAVPVVTVTTAELRAS-AGDPDRVVAIDDPAPHVPRIGGRAAP 1731 Query 1627 MPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAW 1686 P ++AY++YTSGTTG PKGV +TH NVT+L SL RL +VWSQCHS FD S W Sbjct 1732 APD--DIAYVIYTSGTTGVPKGVAVTHHNVTQLLGSLDDRLGLGRVWSQCHSLAFDFSVW 1789 Query 1687 EIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVV 1746 EI+GALL GGRLVIVP+ V SP D H LL+ E V+VL+QTP+A A L + LESVALV+ Sbjct 1790 EIFGALLRGGRLVIVPDDVVRSPEDLHALLIGEGVTVLSQTPSAAAALSPERLESVALVL 1849 Query 1747 AGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLD 1806 GEACP L+DRWAPGR+M+N YGPTETT+ A ++ PLR G PIG PV GAALFVLD Sbjct 1850 GGEACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLRAGGAAVPIGSPVPGAALFVLD 1909 Query 1807 SWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD 1866 LR VP GV GELY+AG GV GY RA LTASRFVACPFGG+G RMYRTGDL W AD Sbjct 1910 GRLRRVPPGVVGELYVAGRGVAAGYLGRAALTASRFVACPFGGTGTRMYRTGDLARWGAD 1969 Query 1867 GQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIA 1926 GQL ++GR D+QVKIRG+RIELGE+ + LA L GV QA VIAR+D G RLV Y T Sbjct 1970 GQLHYVGRADEQVKIRGFRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYIT--- 2026 Query 1927 PGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPA 1986 G DPA LRAQLA RLPGY+VP+AVVV+DALPLT NGKLD RALPAP+Y YRAP Sbjct 2027 -GTADPAELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTRALPAPDYAGGR-YRAPG 2084 Query 1987 GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +E+ +AGI+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 2085 DAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 2125 Score = 1316 bits (3405), Expect = 0.0, Method: Compositional matrix adjust. Identities = 788/1535 (52%), Positives = 975/1535 (64%), Gaps = 99/1535 (6%) Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAY-GWGAHDTVLQCAPLTSDISVEEI 631 AY++ TSGTTG PK V ++H ++A +++ + G G QC D+SV+EI Sbjct 3221 NIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWS---QCHSYGFDVSVQEI 3277 Query 632 FGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIG 688 +G A G RLV S +L AL L+A T+ L A+ A+ Sbjct 3278 WGALAGGGRLVVVPESVTSSPDELHAL---LIAENVTV----------LSQTPSALAALS 3324 Query 689 RSRLRQ-IVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMD 747 L +VIGGE + D+W + G ++++YGPTE TV A ++ Sbjct 3325 PRNLHAALVIGGEPCPAALADRW-----APGRVMINAYGPTETTVDA----VLSTPLAAG 3375 Query 748 GALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA-- 794 LG P+ T+F+ GE+ I G VA GYLG G A Sbjct 3376 AGAPPLGSPVAGATLFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPF 3435 Query 795 DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVE 854 G+ R + TGD V D +G + R D VKI G R+++ E+ +AE V AV Sbjct 3436 GGAGARMYRTGDLVRWDRDGRLHYVARADQQVKIRGHRIELGEIHSALAELDGVEQAAV- 3494 Query 855 LHSGSLGVWFKSQRTREGEQDAA---------AATRIRLV--LVSLGVSSFFVVGVPNIP 903 ++ R GE+ AA R RL L + V + V+ + +P Sbjct 3495 ----------IAREDRPGEKRIVGYLTGTADPAAIRARLAERLPAYMVPAA-VLAIEALP 3543 Query 904 RKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIG 962 PNGK+D+ LP P++ A G A + ++ I+++ LG +G D S G Sbjct 3544 LTPNGKLDARALPA-PEY-AGGAYRAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGGD 3601 Query 963 SLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE--DRFRPLVAAQRP 1020 SL +R++ L RLS+ L A T A LA A GE RF +VAA+RP Sbjct 3602 SLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQLA-------ARLGEGGHRFAAVVAAERP 3654 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 A +PLSFAQ RLWF+ QL P+PVYNM ALRL G +D ALGAA+ DVV RHESLRTVF Sbjct 3655 AVVPLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVF 3714 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 A DG P Q+V+ RAD+G ++DA+ W R+ I + ARH+FDLA EIPLR L R Sbjct 3715 AATDGTPAQVVLPPDRADIGWQVIDASGWSPARVDDVIRDTARHTFDLAAEIPLRAVLLR 3774 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 D+EH+LVAV HHIAADGWS+ PL DL+ AYASR AGR PDW PLPVQYVDYTLWQR Sbjct 3775 CGDEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRA 3834 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 GDLDD S IA QL YWE+ALAGMPERL LPT RPYP VAD RGAS+ V+WPA +QQQ Sbjct 3835 QFGDLDDPHSLIAGQLRYWESALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQ 3894 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 + R+A HNATSFMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVL Sbjct 3895 ISRLAGAHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVL 3954 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RV+++GDP+ AELL +VR RSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ+ Sbjct 3955 RVDVSGDPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNI 4014 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 +L+LG ++ P+P+DTRTARMDL +SLAER++ PAGIGGAVE+RTDVF+ ++ Sbjct 4015 EPTELSLGQVRVIPLPVDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRTDVFDTATVE 4074 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 L +RLR+VL A+ A P R +SSID LD E ARLD GNRA LT P P SIP M AA Sbjct 4075 ALTQRLRRVLAAMTADPGRRLSSIDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAA 4134 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 QVAR P A A+ S+TYR L+E +N+LAH+L GAGPG CVA+L ER A AV A++ Sbjct 4135 QVARTPHAVALTANGRSVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLERSAEAVAAIL 4194 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAA 1619 VLK GAAYLPIDP+ P R+ FML DA P A +T+ RL +D +IDV D ++ Sbjct 4195 GVLKAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIRE 4254 Query 1620 YPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL-PARLSAA--QVWSQC 1676 P T PP PA N+AY++YTSGTTG PKGV +THRN T+LFASL A L AA +VW QC Sbjct 4255 QPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQC 4314 Query 1677 HSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAML-- 1734 HS FD S WEI+GALL GGR+++VP+ V SP D LL+ EHV VL+QTP+A L Sbjct 4315 HSLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPEDLCALLIDEHVDVLSQTPSAFDALQR 4374 Query 1735 --PTQGLESVALVVAGEACPAALVDRWAPGRV----MLNAYGPTETTICAAISAPLRP-- 1786 + L ++ GEA + W G ++N YG TETT+ A+ + Sbjct 4375 ADSARRLNPQTVIFGGEALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDI 4434 Query 1787 GSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACP 1846 + PIG+P++ FVLD WLRPVPAGV GELYIAGAGV GY R GLTASRFVACP Sbjct 4435 DGNVSPIGMPLAHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACP 4494 Query 1847 FGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVV 1906 FGG+G RMYRTGDL W DGQL +LGR D QVKIRGYRIELGE+ +ALAEL GV QA V Sbjct 4495 FGGAGERMYRTGDLARWGTDGQLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATV 4554 Query 1907 IAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKL 1966 IAREDRPGDKRLVGY T G DPA LR LA+RLP YLVPAAVV IDA+PLT NGKL Sbjct 4555 IAREDRPGDKRLVGYVT----GTADPAQLRTALAERLPAYLVPAAVVAIDAMPLTPNGKL 4610 Query 1967 DHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGL---ERVGVDDSFFELGGDSLAAM 2023 D ALPAP+Y + Y APA VE+T+A I+A VL + VG+DDSFF+LGGDSL+AM Sbjct 4611 DTGALPAPDYHGADQYHAPASAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAM 4670 Query 2024 RVIAAINTTLNADLPVRALLHASSTRGLSQLLGRD 2058 R++A +N+ L+ L VRAL A + R L+ LG D Sbjct 4671 RLVAEVNSRLDVHLGVRALFEAPTIRRLAARLGAD 4705 Score = 1268 bits (3281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 714/1240 (58%), Positives = 861/1240 (70%), Gaps = 47/1240 (3%) Query 950 IGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGED 1009 +G + S G SL +R++ LG +S+ L A T A LA P G Sbjct 7 VGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVAQLA-----PRVRGGGR 61 Query 1010 RFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADV 1069 +VA +RPA +PLSFAQ RLWFLDQLQ P+P+YNMA AL+L+G LD L AA+ADV Sbjct 62 TLARVVAGERPAVVPLSFAQSRLWFLDQLQGPSPMYNMAAALKLQGPLDVSVLRAALADV 121 Query 1070 VGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLA 1129 + RHESLRTVF DG P Q+VI A +AD+G D+VD W R++ AI+ AA H+FDL+ Sbjct 122 IARHESLRTVFAVSDGTPHQVVIPAEQADIGWDVVDTAGWSPARMKEAIDAAAGHAFDLS 181 Query 1130 TEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPV 1189 TEIPLR LFR + DEHVLVAVAHHIAADG S+ PL DL+AAY +RCAGR PDW PLPV Sbjct 182 TEIPLRATLFRNSLDEHVLVAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVPDWVPLPV 241 Query 1190 QYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASL 1249 QY+DY LWQR GDL+D DSPIA QL YW+ ALAG+PERL LPT RPYP VAD RGA + Sbjct 242 QYIDYALWQRAQFGDLEDPDSPIAGQLRYWQEALAGLPERLALPTDRPYPAVADHRGARV 301 Query 1250 VVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDN 1309 +DWPAS+QQQV +AR HNATSFMVV AGLAVLL+KL S DVAVGFPIAGR DPALD+ Sbjct 302 DIDWPASLQQQVSALARVHNATSFMVVQAGLAVLLAKLGASCDVAVGFPIAGRGDPALDD 361 Query 1310 LVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHP 1369 LVGFFVNTLVLRV+L+GDP+ E+L +VR RSLAAYE+QDVPFE+LV+RL PTR+L HHP Sbjct 362 LVGFFVNTLVLRVDLSGDPTVGEILARVRQRSLAAYEHQDVPFEILVERLNPTRSLAHHP 421 Query 1370 LIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 LIQVML W+ + +L LG+L+ +PID TARMDL FSL ER++E PAGI G VE+ Sbjct 422 LIQVMLTWRGDDPTRLRLGELEVAALPIDIGTARMDLTFSLCERWTEEGRPAGIAGTVEF 481 Query 1430 RTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAP 1489 RTDVF+A I L ERLR+VL + A P R +SSI+ L+ TE ARLD +GNRA L + Sbjct 482 RTDVFDADTIRTLTERLRRVLDVLTADPGRHLSSIEVLEDTEFARLDIFGNRAAL-GRST 540 Query 1490 TPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLF 1549 T S+P + A R+P A A+ D TYRE+DE +NRLAH L G G+ V LL Sbjct 541 TGASVPALFGAWAQRVPGAVAISSADRCWTYREVDETANRLAHLLIQHGVDRGQYVGLLL 600 Query 1550 ERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLP 1609 +R A AVVA++ VLK GAAY+P+DPA P R+AF++ DA VT AG RSRL G Sbjct 601 DRSAEAVVAILGVLKAGAAYVPMDPAVPAARIAFIVADADLRVVVTDAGSRSRLTGLGAA 660 Query 1610 IIDVVD-ALAAYPGTPP--PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPA- 1665 I+D+ D ALA YP T P P PAA ++A+++YTSGTTGEPKGV ++HRN+T+LFASL Sbjct 661 IVDLDDPALADYPATEPAGPGPAAGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTG 720 Query 1666 -RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL 1724 L QVWSQCHS FD S WEIW ALL GGRLV+V ++VA SP+D LL+ E V+VL Sbjct 721 ITLGPDQVWSQCHSLAFDFSVWEIWAALLHGGRLVVVSDAVARSPDDLRRLLIRERVTVL 780 Query 1725 TQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL 1784 TQTP+A L QGL+SVALV+ E CP LVDRWAP RVM+N YGPTETT+ + S PL Sbjct 781 TQTPSAAGALSPQGLDSVALVIGAEPCPPELVDRWAPDRVMINVYGPTETTMWVSHSRPL 840 Query 1785 RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVA 1844 GSG PPIG PV+GA+ FVLD WL P P GV GELY+AGAGVG GY RA LTASRFVA Sbjct 841 AAGSGAPPIGSPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVA 900 Query 1845 CPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQA 1904 CPFGG+G RMYRTGDLV W ADGQL ++GR D+QVKIRGYRIELGE+ +AL +L GV QA Sbjct 901 CPFGGTGTRMYRTGDLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSALTDLDGVEQA 960 Query 1905 VVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNG 1964 VIARED PG KRLV Y T G DPA +R QLA RLPGY++P+AV+ +DALPLTVNG Sbjct 961 AVIAREDSPGHKRLVAYLT----GTADPAQVRTQLADRLPGYMLPSAVLALDALPLTVNG 1016 Query 1965 KLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMR 2024 KLD RALPAPE N YRAP P E+++A ++AR+LGLERVGVDDSFFELGGDSL+AMR Sbjct 1017 KLDTRALPAPELRAENRYRAPQNPTEESLADVYARLLGLERVGVDDSFFELGGDSLSAMR 1076 Query 2025 VIAAINTTLNADLPVRALLHASSTRGLSQLL----GRDARPTSDPR-------------- 2066 +I A+N L+ADL VRAL A + L+ + GR R + R Sbjct 1077 LITAVNAELDADLTVRALFEAPTVAQLAPRVAAGTGRAGRLVAAERPAVLPLSFAQSRLW 1136 Query 2067 -LVSVHGDNPTEVHASDLTLDRFIDADTLATAV-NLPGPSPELRTVLLTGATGFLGRYLV 2124 + +HG +P A L L +D D L A+ ++ LRT L A R +V Sbjct 1137 FIDQLHGPSPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRT--LFPAPDGAPRQVV 1194 Query 2125 LELLRRLDVDGRLICLVR------AESDEDARRRLEKTFD 2158 LE R +VD +++ R AE+ +A R TFD Sbjct 1195 LE-AERAEVDWQVVDAARWPASWLAEATHEAAR---YTFD 1230 Score = 833 bits (2151), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/1026 (51%), Positives = 638/1026 (63%), Gaps = 63/1026 (6%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV-----IEARRAD 1098 VY + +++ LRG LD L A+ VV RH +L F G P Q++ I R + Sbjct 2664 VYAVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQIIPAEPEIAWRYLE 2723 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L VD ++L++ + +L P L R AD EH V HH+ D Sbjct 2724 LDASDVD------EQLEQLSADERAAVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMD 2777 Query 1159 GWSVAPLTADLSAAY-ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLA 1217 GWS+ L ++ A Y +R P P Y + W L D P A A Sbjct 2778 GWSLPVLLQEIFACYYGARL--------PAPAPYRGFVTW-------LAARDVP--AARA 2820 Query 1218 YWENALAGMPERLRLPTARPYPPVADQRGASLVVDW--PASVQQQVRRIARQHNATSFMV 1275 W L G PT P AD G V + A V +AR+ T V Sbjct 2821 AWRAVLDG----FDTPTLV-APRGADAPGRRGVASFRMAAETTSAVSELARRRRTTVNTV 2875 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGDPSFAEL 1333 + A A LL L+G DVA G ++GR P +++VG +NT+ +R A + A+L Sbjct 2876 LQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRARAAAATTIADL 2935 Query 1334 LGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLG---DL 1390 L Q++ E+Q + + R L +L +++ P+ L DL Sbjct 2936 LDQLQCAHNDTVEHQHLGLNEI------HRVTGQDQLFDTLLVYENYPIDTAALSAADDL 2989 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 AT + L+ + G E +G +E+ TDVF+ AID L +RLR++L Sbjct 2990 TATEFSCHDYNH-----YPLSLQVVPGDE---LGLRLEFDTDVFDPAAIDTLADRLRRLL 3041 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 A+ A P+R + S+D LD TE RL WGNR L+ PA P S+P++ AQVA P A A Sbjct 3042 AAMPADPDRPLRSLDLLDSTEHTRLQRWGNRPALSRPATGP-SLPELFTAQVANAPHAVA 3100 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 + C SMTYRELDEAS RLAH LAG GA PG VALLF R A A+VAM+AVLKTGAAYL Sbjct 3101 LRCAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYL 3160 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAA 1630 PIDPA P R+ FMLGDA PV AV+TAGLR+RL LP++DV A A PG P P PA Sbjct 3161 PIDPALPATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDVA-ATGAQPGGPLPPPAP 3219 Query 1631 VNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 N+AY+LYTSGTTG PKGV +THRNV +L SL A L VWSQCHSYGFD S EIWG Sbjct 3220 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWSQCHSYGFDVSVQEIWG 3279 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 AL GGGRLV+VPESV +SP++ H LL+AE+V+VL+QTP+A+A L + L + ALV+ GE Sbjct 3280 ALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHA-ALVIGGEP 3338 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CPAAL DRWAPGRVM+NAYGPTETT+ A +S PL G+G PP+G PV+GA LFVLD WLR Sbjct 3339 CPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDGWLR 3398 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 PVPAGV GELYIAGAGV GY RAGLTA+RFVACPFGG+GARMYRTGDLV W DG+L Sbjct 3399 PVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGRLH 3458 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 ++ R D QVKIRG+RIELGE+ +ALAEL GV QA VIAREDRPG+KR+VGY T G Sbjct 3459 YVARADQQVKIRGHRIELGEIHSALAELDGVEQAAVIAREDRPGEKRIVGYLT----GTA 3514 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DPA +RA+LA+RLP Y+VPAAV+ I+ALPLT NGKLD RALPAPEY YRAP+ P E Sbjct 3515 DPAAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAG-GAYRAPSTPTE 3573 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 + +AGI+ +VLGL RVGVDDSFF+LGGDSL+AMRVIAA+N L+A L VR L A + Sbjct 3574 EIIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQ 3633 Query 2051 LSQLLG 2056 L+ LG Sbjct 3634 LAARLG 3639 Score = 60.5 bits (145), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 30/53 (57%), Positives = 40/53 (76%), Gaps = 0/53 (0%) Query 2000 VLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 +LG+ RVGV+DSFF+LGGDSL+AMR+IAA+N L A + VR L A + L+ Sbjct 1 MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVAQLA 53 >gi|240169631|ref|ZP_04748290.1| hypothetical protein MkanA1_09977 [Mycobacterium kansasii ATCC 12478] Length=1602 Score = 1968 bits (5098), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1054/1606 (66%), Positives = 1217/1606 (76%), Gaps = 51/1606 (3%) Query 938 LSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLA 996 L+ ++R LG +G D S G SL +R++ L L++ L A TAA LA Sbjct 17 LADSYARVLGLERVGVDESFFDLGGDSLAAMRVIAAINTALDANLTVRTLFEAPTAAQLA 76 Query 997 DYAPTPDAPTGEDRFR--PLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLR 1054 + G DR R PL A +RPA +PLSFAQ RLWFL QL P+PVYNMAVALRLR Sbjct 77 -------SCIGRDRRRLEPLTAGERPAVVPLSFAQSRLWFLHQLSGPSPVYNMAVALRLR 129 Query 1055 GYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRL 1114 G +D ALG A+ADV GRHESLRTV +V G PRQLV+ A RA+ G +++D T WP RL Sbjct 130 GKVDAAALGVALADVAGRHESLRTVILSVQGTPRQLVLPAERAEFGWEVIDTTGWPHARL 189 Query 1115 QRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYA 1174 AIE+AARHSFDLA+EIPL LFRIA DEHVLV V HHIAADGWSVAPL DL AYA Sbjct 190 GYAIEDAARHSFDLASEIPLWAKLFRIAKDEHVLVIVVHHIAADGWSVAPLARDLGEAYA 249 Query 1175 SRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPT 1234 SRCAG+ P WAPLPVQY DYTLWQR LGD+ D DSP+A QL +WE+ LAGMPERL+LPT Sbjct 250 SRCAGQTPGWAPLPVQYADYTLWQRGNLGDVGDRDSPLAEQLRFWEDTLAGMPERLQLPT 309 Query 1235 ARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVA 1294 RPYPPVAD RGAS+ VDWPA +QQ+VRR+AR+HNATSFMVV A LAVLLSKL+GS DV Sbjct 310 DRPYPPVADHRGASVTVDWPARLQQRVRRVAREHNATSFMVVQAALAVLLSKLTGSADVP 369 Query 1295 VGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEV 1354 VG P+AGR+DPALD LVGFFVNTLVLRV LAGDP+ AE+L QVR RSLAAYE+QDVPFEV Sbjct 370 VGVPVAGRADPALDELVGFFVNTLVLRVELAGDPTVAEVLAQVRERSLAAYEHQDVPFEV 429 Query 1355 LVDRLKPTRALTHHPLIQVMLAWQDNPVGQLN-------LGDLQATPMPIDTRTARMDLV 1407 LV+RL PTR+ THHPLIQV+ AWQ+ P G +N LGDL+ T MPID TARMDL Sbjct 430 LVERLNPTRSRTHHPLIQVLAAWQNFP-GHVNEPATGLALGDLRVTSMPIDAHTARMDLT 488 Query 1408 FSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDAL 1467 SLAERFS+ EPAGIGG VE+RTDVF+A +I LI RL+K+L ++A P +SSID L Sbjct 489 ISLAERFSDAGEPAGIGGTVEFRTDVFDAASIRTLIRRLQKLLNVMSADPAARLSSIDML 548 Query 1468 DGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEAS 1527 D E A+LDE NRAVLT PA S+P +LAAQ AR P A AV CG +SMTYRE DEAS Sbjct 549 DDAEYAQLDERANRAVLTQPALPRRSLPALLAAQAARTPAAVAVSCGSSSMTYREFDEAS 608 Query 1528 NRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGD 1587 NRLAH L G G CVALLF RC PA+VAM AVLKTGAAYLP+DPA P R+ FML D Sbjct 609 NRLAHVLTDHGVVSGSCVALLFSRCIPAIVAMTAVLKTGAAYLPVDPALPAARIEFMLAD 668 Query 1588 AVPVAAVTTAGLRSRLAGHDLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEP 1646 A PVAA+TT GL RL G LPII+V D +A YP T P PA+ ++AY+ YTSGTTG P Sbjct 669 AAPVAAITTVGLAGRLTGRGLPIIEVEDPRIAGYPSTGLPEPASDDIAYLTYTSGTTGVP 728 Query 1647 KGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVA 1706 K V ITH NVT+L SL A L QVW+QCHSY FD S WEIWGAL GGGRLV+VPE++ Sbjct 729 KAVAITHHNVTQLLESLSAGLPPGQVWTQCHSYAFDFSVWEIWGALSGGGRLVVVPEALT 788 Query 1707 ASPNDFHGLLVAEHVSVLTQTPAAVAMLPT---------QGLESVALVVAGEACPAALVD 1757 ASP D H LL EHV VL+QTP+A L T L +V GEA + Sbjct 789 ASPTDLHALLATEHVGVLSQTPSAFDALQTADTLQPELRHQLALQTVVFGGEALEPQRLR 848 Query 1758 RW---APGR-VMLNAYGPTETTICAAISAPLR--PGSGMPPIGVPVSGAALFVLDSWLRP 1811 W PG ++N YG TETT+ A+ + S PIGVP++ ALFVLD WLRP Sbjct 849 DWLHNHPGLPRLINMYGATETTVHASFREIVSGDADSSASPIGVPLAHLALFVLDKWLRP 908 Query 1812 VPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGA---RMYRTGDLVCWRADGQ 1868 VP GV GELY+AGAGVG+GYWRR+GLTASRFVACPF G+GA RMYR+GDLV W DGQ Sbjct 909 VPTGVVGELYVAGAGVGLGYWRRSGLTASRFVACPFAGAGAPARRMYRSGDLVRWLPDGQ 968 Query 1869 LEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPG 1928 LE+LGR D+QVKIRGYRIELGEV ALA L GV Q+VVIARED+PGD+ LVGY T G Sbjct 969 LEYLGRVDEQVKIRGYRIELGEVRAALAALDGVYQSVVIAREDQPGDRCLVGYVT----G 1024 Query 1929 AVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGP 1988 DPAGLRA LA+RLP Y+VPAAV+V+DALPLTVNGKLD RALPAPEY + APA P Sbjct 1025 TADPAGLRAALAERLPSYMVPAAVLVVDALPLTVNGKLDTRALPAPEYRSADRDLAPATP 1084 Query 1989 VEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASST 2048 VE+ +A +ARVLGLERVGV+ SFF+LGG+SL+AMR+IAA+N+ L+A L V L A + Sbjct 1085 VEEILADTYARVLGLERVGVEQSFFDLGGNSLSAMRLIAAVNSALDAHLTVPILFDAPTV 1144 Query 2049 RGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPELR 2108 RGL++ LG A + SVHG + TE+HA DL LD+FI+ TLA A LPGPS E+R Sbjct 1145 RGLARHLGGHA---TSETFKSVHGRDATELHAGDLMLDKFIEPATLAAAPTLPGPSAEVR 1201 Query 2109 TVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDEDARRRLEKTFDSGDPELLRH 2167 TVLLTGATGFLGRYL L+ L +++ V G LICLVRA+SDE+ARRRL+KTF GDP+LL H Sbjct 1202 TVLLTGATGFLGRYLALQWLEQMELVGGTLICLVRADSDEEARRRLDKTF-GGDPKLLAH 1260 Query 2168 FKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA-FPYHELFGPNVA 2226 ++ELAAD L+V+AGDK E DLGLD+ W+RLA+ VDLIVDSAA+VN PY +LF PNV Sbjct 1261 YRELAADHLQVIAGDKGEIDLGLDRRTWQRLAQAVDLIVDSAAVVNGVLPYRDLFTPNVV 1320 Query 2227 GTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTS 2286 GT ELIR+ALTT+LKP++YVSTA+VG I+PSAFTEDADIRVISPTRT+DG A GYG S Sbjct 1321 GTVELIRLALTTRLKPYSYVSTANVGDQIQPSAFTEDADIRVISPTRTLDGSVANGYGNS 1380 Query 2287 KWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSF 2346 KWAGEVLLR ANDL LPVAVFRCGMILADTSYAGQLNMSD VTRMVLS++A G+AP SF Sbjct 1381 KWAGEVLLRAANDLYGLPVAVFRCGMILADTSYAGQLNMSDTVTRMVLSVVAAGVAPASF 1440 Query 2347 YEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYV 2406 Y+ D++GNRQRAHFDGLPV FVAEAI LGA+V + GFATYHVMN HDDGIGLDEYV Sbjct 1441 YQRDAKGNRQRAHFDGLPVEFVAEAITALGAQV----VDGFATYHVMNSHDDGIGLDEYV 1496 Query 2407 DWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGC 2466 DW+IEAGYPI RIDDFAEWL+RFE +L ALPDRQRRHSVL ML +S+RL+PL+PTRG Sbjct 1497 DWVIEAGYPIERIDDFAEWLRRFETALRALPDRQRRHSVLQMLPLRDSERLRPLEPTRGS 1556 Query 2467 SAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 S T RFRAAV+ AK+G DKDNPDIPHVSAP I+ YVT+LQLLGLL Sbjct 1557 SVQTARFRAAVQEAKLGPDKDNPDIPHVSAPVILKYVTDLQLLGLL 1602 Score = 109 bits (272), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 74/156 (48%), Positives = 93/156 (60%), Gaps = 20/156 (12%) Query 1978 DTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADL 2037 DT+ YRAP PVE+ +A +ARVLGLERVGVD+SFF+LGGDSLAAMRVIAAINT L+A+L Sbjct 2 DTDRYRAPGTPVEQILADSYARVLGLERVGVDESFFDLGGDSLAAMRVIAAINTALDANL 61 Query 2038 PVRALLHASSTRGLSQLLGRD----------ARPTSDP------RLVSVH---GDNPTEV 2078 VR L A + L+ +GRD RP P RL +H G +P Sbjct 62 TVRTLFEAPTAAQLASCIGRDRRRLEPLTAGERPAVVPLSFAQSRLWFLHQLSGPSPVYN 121 Query 2079 HASDLTLDRFIDADTLATAV-NLPGPSPELRTVLLT 2113 A L L +DA L A+ ++ G LRTV+L+ Sbjct 122 MAVALRLRGKVDAAALGVALADVAGRHESLRTVILS 157 Score = 94.0 bits (232), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 125/449 (28%), Positives = 188/449 (42%), Gaps = 39/449 (8%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY+ TSGTTG PK V I+H ++ +++S G T QC D SV EI+G Sbjct 716 AYLTYTSGTTGVPKAVAITHHNVTQLLESLSAGLPPGQVWT--QCHSYAFDFSVWEIWGA 773 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 + G RLV + DL AL+ + P+A L AD + + Sbjct 774 LSGGGRLVVVPEALTASPTDLHALL--ATEHVGVLSQTPSAFDALQTADTLQPELRHQLA 831 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGI-SLLSSYGPTEATVVATFLPIVCDQTTMDGAL 750 L+ +V GGEA+ + WL + G+ L++ YG TE TV A+F IV D + Sbjct 832 LQTVVFGGEALEPQRLRDWLHN--HPGLPRLINMYGATETTVHASFREIVSGDA--DSSA 887 Query 751 LRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYL---GIDGDGF--GTVTAA 794 +G P+ +F+ GE+ + G V GY G+ F A Sbjct 888 SPIGVPLAHLALFVLDKWLRPVPTGVVGELYVAGAGVGLGYWRRSGLTASRFVACPFAGA 947 Query 795 DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVE 854 RR + +GD V +G + GR D VKI G R+++ EV +A V V Sbjct 948 GAPARRMYRSGDLVRWLPDGQLEYLGRVDEQVKIRGYRIELGEVRAALAALDGVYQSVVI 1007 Query 855 LHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKI 910 G V + + AA A R+ +V V+ V +P NGK+ Sbjct 1008 AREDQPGDRCLVGYVTGTADPAGLRAALAERLPSYMVPAA-----VLVVDALPLTVNGKL 1062 Query 911 DSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRI 969 D+ LP P++ +A + A L+ ++R LG +G + S G SL +R+ Sbjct 1063 DTRALP-APEYRSADRDLAPATPVEEILADTYARVLGLERVGVEQSFFDLGGNSLSAMRL 1121 Query 970 LPETRRYLGWRLSLLDLIGADTAANLADY 998 + L L++ L A T LA + Sbjct 1122 IAAVNSALDAHLTVPILFDAPTVRGLARH 1150 >gi|336457976|gb|EGO36964.1| amino acid adenylation enzyme/thioester reductase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=4019 Score = 1925 bits (4987), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1103/1991 (56%), Positives = 1347/1991 (68%), Gaps = 104/1991 (5%) Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAY-GWGAHDTVLQCAPLTSDISVEEI 631 AY++ TSGTTG PK V ++H ++A +++ + G G QC D+SV+EI Sbjct 2082 NIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWS---QCHSYGFDVSVQEI 2138 Query 632 FGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIG 688 +G A G RLV S +L AL L+A T+ L A+ A+ Sbjct 2139 WGALAGGGRLVVVPESVTSSPDELHAL---LIAENVTV----------LSQTPSALAALS 2185 Query 689 RSRLRQ-IVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMD 747 L +VIGGE + D+W + G ++++YGPTE TV A ++ Sbjct 2186 PRNLHAALVIGGEPCPAALADRW-----APGRVMINAYGPTETTVDA----VLSTPLAAG 2236 Query 748 GALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA-- 794 LG P+ T+F+ GE+ I G VA GYLG G A Sbjct 2237 AGAPPLGSPVAGATLFVLDAWLRQVPAGVTGELYIAGAGVAAGYLGRPGLTAARFVACPF 2296 Query 795 DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVE 854 + R + TGD V D +G + R D VKI G R+++ E+ +AE V +VAV Sbjct 2297 GDAGARMYRTGDLVRWDRDGRLHYVARADQQVKIRGHRIELGEIHSALAELDGVGEVAV- 2355 Query 855 LHSGSLGVWFKSQRTREGEQDAA---------AATRIRLV--LVSLGVSSFFVVGVPNIP 903 ++ R GE+ AA R RL L + V + V+ + +P Sbjct 2356 ----------IAREDRPGEKRIVGYLTGTADPAAIRARLAERLPAYMVPAA-VLAIEALP 2404 Query 904 RKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIG 962 PNGK+D+ LP P++ A G A + ++ I+++ LG +G D S G Sbjct 2405 LTPNGKLDARALPA-PEY-AGGAYRAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGGD 2462 Query 963 SLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE--DRFRPLVAAQRP 1020 SL +R++ L RLS+ L A T A LA A GE RF +VAA+RP Sbjct 2463 SLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQLA-------ARLGEGGHRFAAVVAAERP 2515 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 A +PLSFAQ RLWF+ QL P+PVYNM ALRL G +D ALGAA+ DVV RHESLRTVF Sbjct 2516 AVVPLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVF 2575 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 A DG P Q+V+ RAD+G ++DA+ W R+ AI + ARH+FDLA EIPLR L R Sbjct 2576 AATDGTPAQVVLPPDRADIGWQVIDASGWSPARVDDAIRDTARHTFDLAAEIPLRAVLLR 2635 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 +EH+LVAV HHIAADGWS+ PL DL+ AYASR AGR PDW PLPVQYVDYTLWQR Sbjct 2636 CGAEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRA 2695 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 GDLDD S IA QL YWE+ LAGMPERL LPT RPYP VAD RGAS+ V+WPA +QQQ Sbjct 2696 QFGDLDDPHSLIAGQLRYWEHTLAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQ 2755 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 + R+AR HNATSFMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVL Sbjct 2756 ISRLARAHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVL 2815 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RV+++GDP+ ELL +VR RSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ+ Sbjct 2816 RVDVSGDPTVGELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNI 2875 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 +L+LG ++ TP+P+DTRTARMDL +SLAER++ PAGIGGAVE+RTDVF+ ++ Sbjct 2876 EPTELSLGQVRVTPLPVDTRTARMDLAWSLAERWAPDGSPAGIGGAVEFRTDVFDTATVE 2935 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 L +RLR+VL A+ A P R +SSID LD E ARLD GNRA LT P P SIP M AA Sbjct 2936 ALTQRLRRVLAAMTADPGRRLSSIDLLDPDEHARLDALGNRAALTRPQNPPTSIPAMFAA 2995 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Q+AR P A A+ S+TYR L+E +N+LAH+L GAGPG+CVALL ER A AV A++ Sbjct 2996 QMARTPHAVALTANGRSVTYRRLEEHANQLAHQLIRYGAGPGDCVALLLERSAEAVAAIL 3055 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAA 1619 VLK GAAYLPIDP+ P R+ FML DA P A +T+ RL + +IDV D ++ Sbjct 3056 GVLKAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQDYHQTVIDVDDPSIRE 3115 Query 1620 YPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL-PARLSAA--QVWSQC 1676 P T PP PA N+AY++YTSGTTG PKGV +THRN T+LFASL A L AA +VW QC Sbjct 3116 QPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQC 3175 Query 1677 HSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAML-- 1734 HS FD S WEI+GALL GGR+++VP+ V SP D LL+ E V VL+QTP+A L Sbjct 3176 HSLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPEDLCALLIEERVDVLSQTPSAFDALQR 3235 Query 1735 --PTQGLESVALVVAGEACPAALVDRWAPGRV----MLNAYGPTETTICAAISAPLRP-- 1786 + L ++ GEA + W G ++N YG TETT+ A+ + Sbjct 3236 ADSARRLNPQTVIFGGEALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDI 3295 Query 1787 GSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACP 1846 + PIG+P++ FVLD WLRPVPAGV GELYIAGAGV GY R GLTASRFVACP Sbjct 3296 DGNVSPIGMPLAHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACP 3355 Query 1847 FGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVV 1906 FGG+G RMYRTGDL W ADGQL++LGR D+QVKIRGYRIELGE+ +ALAEL V QA V Sbjct 3356 FGGAGERMYRTGDLARWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAELDSVEQAAV 3415 Query 1907 IAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKL 1966 IAREDRPGDKRLV Y T G DPA LR L +RLP YLVPAAV+V+DALPLT +GKL Sbjct 3416 IAREDRPGDKRLVAYVT----GTADPAQLRTALTERLPAYLVPAAVLVLDALPLTPSGKL 3471 Query 1967 DHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGL-ERVGVDDSFFELGGDSLAAMRV 2025 D ALPAP+Y Y APAG VE+ +A ++A+VLGL RVGV +SFF+LGGDSL+AMR+ Sbjct 3472 DTGALPAPDYQGPEDYLAPAGAVEEILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRL 3531 Query 2026 IAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPR--LVSVHGDNPTEVHASDL 2083 +AAI L+ LPVRA+ A S R LSQ L D R SVHG + TEV+ASDL Sbjct 3532 VAAIYNALDIHLPVRAVFEAPSVRSLSQRLNADPAVAQGLRADFASVHGRDATEVYASDL 3591 Query 2084 TLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV-DGRLICLVR 2142 TLD+FIDA TL+ A LPGP E+RTVLLTGATGFLGRYLVL+ L RL++ DG+LICLVR Sbjct 3592 TLDKFIDAATLSAAPALPGPGAEVRTVLLTGATGFLGRYLVLQWLERLELADGKLICLVR 3651 Query 2143 AESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETV 2202 A SD+DARRRLE+TFDSGDP LLR+F ELAAD LEV+AGDK +LGLD W+RLA+TV Sbjct 3652 AASDDDARRRLERTFDSGDPALLRYFHELAADHLEVIAGDKGRANLGLDDRTWQRLADTV 3711 Query 2203 DLIVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFT 2261 DLIVD+AA+VN PY ELFGPNVAGTAELIR+AL+T+LKP++YVSTA+VG IEPSAFT Sbjct 3712 DLIVDAAAVVNGVLPYQELFGPNVAGTAELIRLALSTRLKPYSYVSTANVGDQIEPSAFT 3771 Query 2262 EDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAG 2321 EDADIRV P RT+DGG+ GYG SKWAGEVLLREA+DLC LPV+VFRC MILADTSYAG Sbjct 3772 EDADIRVAGPIRTIDGGYGNGYGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTSYAG 3831 Query 2322 QLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAG 2381 QLN+SD TR++ S++A+G+APRSFY D+ GNRQRAHFD LPV FVAEAIA LGA+V Sbjct 3832 QLNLSDMFTRLLFSVVASGVAPRSFYRLDAHGNRQRAHFDALPVEFVAEAIATLGAQVGR 3891 Query 2382 SSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQR 2441 + GFATYHVMNPHDDGIGLDEYVDWLIEAGY I R+DDF +WL R E +L ALP+RQR Sbjct 3892 DAGIGFATYHVMNPHDDGIGLDEYVDWLIEAGYLIERVDDFDQWLHRMETALHALPERQR 3951 Query 2442 RHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIIN 2501 SVL +L ++ + P P RGC PT+RFRAAV+ AK+G+D DIPH++AP I+ Sbjct 3952 HQSVLQLLALRKARHVPPADPARGCLGPTERFRAAVQEAKIGADN---DIPHITAPVIVK 4008 Query 2502 YVTNLQLLGLL 2512 YVT+LQLLGLL Sbjct 4009 YVTDLQLLGLL 4019 Score = 822 bits (2123), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/1027 (50%), Positives = 635/1027 (62%), Gaps = 63/1027 (6%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV-----IEARRAD 1098 VY + +++ LRG LD L A+ VV RH +L F G P Q++ + R + Sbjct 1525 VYAVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQIIPAEPEMAWRYLE 1584 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L +D ++L++ + +L P L R AD EH V HH+ D Sbjct 1585 LDGGDID------EQLEQLSADERAAVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMD 1638 Query 1159 GWSVAPLTADLSAAY-ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLA 1217 GWS+ L ++ A Y +R P P Y + W L D P A A Sbjct 1639 GWSLPVLLQEIFACYYGARL--------PAPAPYRGFVTW-------LAARDVPAAR--A 1681 Query 1218 YWENALAGMPERLRLPTARPYPPVADQRGASLVVDW--PASVQQQVRRIARQHNATSFMV 1275 W L G PT P AD G V + A V +AR+ T V Sbjct 1682 AWRAVLDG----FDTPTLVA-PRGADAPGRRGVASFRVAAETTSAVSELARRRRTTVNTV 1736 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGDPSFAEL 1333 + A A LL L+G DVA G ++GR P +++VG +NT+ +R + + A+L Sbjct 1737 LQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRAHATAATTIADL 1796 Query 1334 LGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLG---DL 1390 + Q++ E+Q + + R L +L +++ P+ L DL Sbjct 1797 VDQLQRAHNHTVEHQHLALNEI------HRITGQDQLFDTLLVYENYPIDTAALSAADDL 1850 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 AT + L+ + G E +G +E+ TDVF+ AID L +RLRK+L Sbjct 1851 TATEFSCHDYNH-----YPLSLQVVPGDE---LGLRLEFDTDVFDPAAIDTLADRLRKLL 1902 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 A+ A P+R + S+D LD TE RL WGNR L+ PA P S+P++ AAQVA P A A Sbjct 1903 AAMPADPDRPLRSLDLLDATEHTRLQRWGNRPALSRPATGP-SLPELFAAQVANAPHAVA 1961 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 + SMTYRELDEAS RLAH LAG GA PG VALLF R A A+VAM+AVLKTGAAYL Sbjct 1962 LRYAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYL 2021 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAA 1630 PIDPA P R+ FMLGDA PV AV+TA LR+RL LP++DV A A PG P P PA Sbjct 2022 PIDPALPATRIEFMLGDAAPVVAVSTADLRARLEAFGLPVVDVA-ATGAQPGGPLPAPAP 2080 Query 1631 VNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 N+AY+LYTSGTTG PKGV +THRNV +L SL A L VWSQCHSYGFD S EIWG Sbjct 2081 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWSQCHSYGFDVSVQEIWG 2140 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 AL GGGRLV+VPESV +SP++ H LL+AE+V+VL+QTP+A+A L + L + ALV+ GE Sbjct 2141 ALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHA-ALVIGGEP 2199 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CPAAL DRWAPGRVM+NAYGPTETT+ A +S PL G+G PP+G PV+GA LFVLD+WLR Sbjct 2200 CPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDAWLR 2259 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 VPAGV GELYIAGAGV GY R GLTA+RFVACPFG +GARMYRTGDLV W DG+L Sbjct 2260 QVPAGVTGELYIAGAGVAAGYLGRPGLTAARFVACPFGDAGARMYRTGDLVRWDRDGRLH 2319 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 ++ R D QVKIRG+RIELGE+ +ALAEL GVG+ VIAREDRPG+KR+VGY T G Sbjct 2320 YVARADQQVKIRGHRIELGEIHSALAELDGVGEVAVIAREDRPGEKRIVGYLT----GTA 2375 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DPA +RA+LA+RLP Y+VPAAV+ I+ALPLT NGKLD RALPAPEY YRAP+ P E Sbjct 2376 DPAAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAG-GAYRAPSTPTE 2434 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 + +AGI+ +VLGL RVGVDDSFF+LGGDSL+AMRVIAA+N L+A L VR L A + Sbjct 2435 EIIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQ 2494 Query 2051 LSQLLGR 2057 L+ LG Sbjct 2495 LAARLGE 2501 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/1028 (48%), Positives = 609/1028 (60%), Gaps = 69/1028 (6%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A PL+ Q +W + + + + +++ G + +AL A+ V E R F Sbjct 7 AFPLTRGQLDIWLSQEAGFAGTQWQLGLLVKIDGKVHRDALEQAITQAVAEAEPGRVSFF 66 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRI 1141 +DG Q I+ +L + A P + R L ++ + LF+ Sbjct 67 ELDGQVVQKPIDYPHVELAFHDLTDHADPVAEAREMSSAIQRTPMPLNGQM-FKFVLFQT 125 Query 1142 ADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREI 1201 DE L HHIA DG +A + ++ Y++ AG+ P+P Y + Sbjct 126 GHDEFYLFGCCHHIAIDGLGMALVCRRVATIYSAMVAGK-----PIPDAYFGTV----QD 176 Query 1202 LGDLD---DSDSPIAAQLAYWENALAGMPERL---RLPTARPYPPVADQRGASLVVDWPA 1255 L DL+ ++ A AYW L PE RLP A D S V Sbjct 177 LIDLESGYEASPDYAEDKAYWSEHLP--PESGPVDRLPDAEGE---RDHYSPSASVQLDP 231 Query 1256 SVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGS-PDVAVGFPIAGRSDPALDNLVGFF 1314 SV +++ ++++ F V A A+L+ SGS +VA+ FP++ R P L Sbjct 232 SVANRIKELSKKLAIRRFSVTTAACALLVRGWSGSGSEVALDFPVSRRVRPESKTLPAML 291 Query 1315 VNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVD---RLKPTRA------- 1364 + L ++ A + + A+ V R +Q P L R P R Sbjct 292 AGVVPLVLSTAPESTVADFCKHVDKRIRELLAHQRFPVHTLEGDGLRQAPNRVGINFIPS 351 Query 1365 -LTHHPLIQVMLAWQDN--PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPA 1421 LT P A N PVG L L A D +F A Sbjct 352 RLTLDPAGSPATASYTNHGPVGHFGLFFLGAG-----------DQLFL---------STA 391 Query 1422 GIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNR 1481 G G F + + L RL+++L A+ P+R +SSI+ L G E A +D W NR Sbjct 392 GPG-------QPFASFGVADLAGRLQQILAAMTEDPDRPLSSIELLTGDEPALIDRWSNR 444 Query 1482 AVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGP 1541 LT PAP PVSIPQ A V R P+A AV G S+TY +LDEASNRL H LA G GP Sbjct 445 PALTEPAPAPVSIPQAFAEHVQRTPDAVAVTFGATSLTYAQLDEASNRLGHLLADHGVGP 504 Query 1542 GECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRS 1601 G+CVA++F RCA A+V+M+AVLKTGAAY+PIDPA+ R+ F+L DA P A +TT+ LRS Sbjct 505 GDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADAAPSAVITTSDLRS 564 Query 1602 RLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLF 1660 RL HDL ++DV D A+ A PGT P PA + AYI+YTSGTTG PKGV I H NVT L Sbjct 565 RLDDHDLLVVDVHDPAVEAQPGTALPWPAPEDTAYIIYTSGTTGTPKGVAIPHLNVTWLI 624 Query 1661 ASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEH 1720 SL A L VW+QCHS FD S WEI+GALL G RL++VPESVA+SP DFH LLVAE Sbjct 625 ESLDAGLPPGNVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESVASSPEDFHALLVAEQ 684 Query 1721 VSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWA-PGRVMLNAYGPTETTICAA 1779 VSVLTQTP+AVAML +GLES ALVVAGEACP +VDRWA PGRVML+AYGPTETT+CA+ Sbjct 685 VSVLTQTPSAVAMLSPEGLESTALVVAGEACPTDVVDRWAAPGRVMLDAYGPTETTVCAS 744 Query 1780 ISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTA 1839 IS PL G + PIG P++GAA+FVLD WL+PVPAGV GELY+AG GVG GY RR GLTA Sbjct 745 ISTPLTAGDPVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAGRGVGHGYVRRPGLTA 804 Query 1840 SRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELA 1899 SRFV PFG G+RMYRTGDLVCW DGQL++LGR D+QVKIRG+RIELGE+ + LA L Sbjct 805 SRFVPNPFGAPGSRMYRTGDLVCWGPDGQLQYLGRADEQVKIRGFRIELGEIQSVLAGLD 864 Query 1900 GVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALP 1959 GV QA V+AREDRPGDKRLVGY T G DPA LRAQLA RLP Y+VP AV+V+DALP Sbjct 865 GVEQAAVVAREDRPGDKRLVGYIT----GTADPAELRAQLADRLPPYMVPTAVMVLDALP 920 Query 1960 LTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDS 2019 LT NGKLD RALP+PEY YRAP +E+ +A I+A+VLG+ERVGVDDSFF+LGGDS Sbjct 921 LTGNGKLDKRALPSPEYA-AGEYRAPGDAIEEILADIYAQVLGVERVGVDDSFFDLGGDS 979 Query 2020 LAAMRVIA 2027 + +M+V+A Sbjct 980 ILSMQVVA 987 Score = 98.6 bits (244), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 141/527 (27%), Positives = 213/527 (41%), Gaps = 60/527 (11%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L G PGD + I ++A G Y D A S + + + Sbjct 497 LADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADAAPSAV 556 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLA----TKTAYIMPTSGTTGQPKLV 590 +T D+ + + HD L V + + L TAYI+ TSGTTG PK V Sbjct 557 ITTSDLRSR---LDDHDLLVVDVHDPAVEAQPGTALPWPAPEDTAYIIYTSGTTGTPKGV 613 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAM 647 I H ++ +++ G + QC D SV EIFG G RL+ S A Sbjct 614 AIPHLNVTWLIESLDAGLPPG--NVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESVAS 671 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 D AL LVA + +++ + +L +G A+ V+ GEA V Sbjct 672 SPEDFHAL---LVAEQVSVLTQTPSAVAMLSPEGLESTAL--------VVAGEACPTDVV 720 Query 708 DKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL--- 764 D+W A+ G +L +YGPTE TV A+ + T ++ +G PI +F+ Sbjct 721 DRW----AAPGRVMLDAYGPTETTVCAS----ISTPLTAGDPVVPIGSPIAGAAMFVLDK 772 Query 765 --------AFGEVVIVGDLVADGYL---GIDGDGF-GTVTAADGSRRRAFATGDRVTVDA 812 GE+ + G V GY+ G+ F A GSR + TGD V Sbjct 773 WLQPVPAGVVGELYLAGRGVGHGYVRRPGLTASRFVPNPFGAPGSR--MYRTGDLVCWGP 830 Query 813 EGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQR 868 +G + GR D VKI G R+++ E+ +A V AV G V + + Sbjct 831 DGQLQYLGRADEQVKIRGFRIELGEIQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGT 890 Query 869 TREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNT 928 E A A R+ +V V+ + +P NGK+D LP P++ AAG Sbjct 891 ADPAELRAQLADRLPPYMVPTA-----VMVLDALPLTGNGKLDKRALPS-PEY-AAGEYR 943 Query 929 AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 A L+ I+++ LG +G D S G S+ ++++ R Sbjct 944 APGDAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARAR 990 >gi|41407340|ref|NP_960176.1| hypothetical protein MAP1242 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395692|gb|AAS03559.1| PstA [Mycobacterium avium subsp. paratuberculosis K-10] Length=4027 Score = 1924 bits (4984), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1102/1991 (56%), Positives = 1347/1991 (68%), Gaps = 104/1991 (5%) Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAY-GWGAHDTVLQCAPLTSDISVEEI 631 AY++ TSGTTG PK V ++H ++A +++ + G G QC D+SV+EI Sbjct 2090 NIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWS---QCHSYGFDVSVQEI 2146 Query 632 FGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIG 688 +G A G RLV S +L AL L+A T+ L A+ A+ Sbjct 2147 WGALAGGGRLVVVPESVTSSPDELHAL---LIAENVTV----------LSQTPSALAALS 2193 Query 689 RSRLRQ-IVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMD 747 L +VIGGE + D+W + G ++++YGPTE TV A ++ Sbjct 2194 PRNLHAALVIGGEPCPAALADRW-----APGRVMINAYGPTETTVDA----VLSTPLAAG 2244 Query 748 GALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA-- 794 LG P+ T+F+ GE+ I G VA GYLG G A Sbjct 2245 AGAPPLGSPVAGATLFVLDAWLRQVPAGVTGELYIAGAGVAAGYLGRPGLTAARFVACPF 2304 Query 795 DGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVE 854 + R + TGD V D +G + R D VKI G R+++ E+ +AE V +VAV Sbjct 2305 GDAGARMYRTGDLVRWDRDGRLHYVARADQQVKIRGHRIELGEIHSALAELDGVGEVAV- 2363 Query 855 LHSGSLGVWFKSQRTREGEQDAA---------AATRIRLV--LVSLGVSSFFVVGVPNIP 903 ++ R GE+ AA R RL L + V + V+ + +P Sbjct 2364 ----------IAREDRPGEKRIVGYLTGTADPAAIRARLAERLPAYMVPAA-VLAIEALP 2412 Query 904 RKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIG 962 PNGK+D+ LP P++ A G A + ++ I+++ LG +G D S G Sbjct 2413 LTPNGKLDARALPA-PEY-AGGAYRAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGGD 2470 Query 963 SLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE--DRFRPLVAAQRP 1020 SL +R++ L RLS+ L A T A LA A GE RF +VAA+RP Sbjct 2471 SLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQLA-------ARLGEGGHRFAAVVAAERP 2523 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 A +PLSFAQ RLWF+ QL P+PVYNM ALRL G +D ALGAA+ DVV RHESLRTVF Sbjct 2524 AVVPLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVF 2583 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 A DG P Q+V+ RAD+G ++DA+ W R+ AI + ARH+FDLA EIPLR L R Sbjct 2584 AATDGTPAQVVLPPDRADIGWQVIDASGWSPARVDDAIRDTARHTFDLAAEIPLRAVLLR 2643 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 +EH+LVAV HHIAADGWS+ PL DL+ AYASR AGR PDW PLPVQYVDYTLWQR Sbjct 2644 CGAEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRA 2703 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 GDLDD S IA QL YWE+ LAGMPERL LPT RPYP VAD RGAS+ V+WPA +QQQ Sbjct 2704 QFGDLDDPHSLIAGQLRYWEHTLAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQ 2763 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 + R+AR HNATSFMVV A LAVLL+K+S S DVAVGFPIAGR DPALD++VGFFVNTLVL Sbjct 2764 ISRLARAHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVL 2823 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 RV+++GDP+ ELL +VR RSLAAYE+QDVPFEVLV+RL P R+L HHPL+QVMLAWQ+ Sbjct 2824 RVDVSGDPTVGELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNI 2883 Query 1381 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAID 1440 +L+LG ++ TP+P+DTRTARMDL +SLAER++ PAGIGGAVE+RTDVF+ ++ Sbjct 2884 EPTELSLGQVRVTPLPVDTRTARMDLAWSLAERWAPDGSPAGIGGAVEFRTDVFDTATVE 2943 Query 1441 VLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 L +RLR+VL A+ A P R +SSID LD E ARLD GNRA LT P P SIP M AA Sbjct 2944 ALTQRLRRVLAAMTADPGRRLSSIDLLDPDEHARLDALGNRAALTRPQNPPTSIPAMFAA 3003 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 Q+AR P A A+ S+TYR L+E +N+LAH+L GAGPG+CVALL ER A AV A++ Sbjct 3004 QMARTPHAVALTANGRSVTYRRLEEHANQLAHQLIRYGAGPGDCVALLLERSAEAVAAIL 3063 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAA 1619 VLK GAAYLPIDP+ P R+ FML DA P A +T+ RL + +IDV D ++ Sbjct 3064 GVLKAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQDYHQTVIDVDDPSIRE 3123 Query 1620 YPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL-PARLSAA--QVWSQC 1676 P T PP PA N+AY++YTSGTTG PKGV +THRN T+LFASL A L AA +VW QC Sbjct 3124 QPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQC 3183 Query 1677 HSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAML-- 1734 HS FD S WEI+GALL GGR+++VP+ V SP D LL+ E V VL+QTP+A L Sbjct 3184 HSLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPEDLCALLIEERVDVLSQTPSAFDALQR 3243 Query 1735 --PTQGLESVALVVAGEACPAALVDRWAPGRV----MLNAYGPTETTICAAISAPLRP-- 1786 + L ++ GEA + W G ++N YG TETT+ A+ + Sbjct 3244 ADSARRLNPQTVIFGGEALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDI 3303 Query 1787 GSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACP 1846 + PIG+P++ FVLD WLRPVPAGV GELYIAGAGV GY R GLTASRFVACP Sbjct 3304 DGNVSPIGMPLAHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACP 3363 Query 1847 FGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVV 1906 FGG+G RMYRTGDL W ADGQL++LGR D+QVKIRGYRIELGE+ +ALAEL V QA V Sbjct 3364 FGGAGERMYRTGDLARWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAELDSVEQAAV 3423 Query 1907 IAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKL 1966 IAREDRPGD+RLV Y T G DPA LR L +RLP YLVPAAV+V+DALPLT +GKL Sbjct 3424 IAREDRPGDERLVAYVT----GTADPAQLRTALTERLPAYLVPAAVLVLDALPLTPSGKL 3479 Query 1967 DHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGL-ERVGVDDSFFELGGDSLAAMRV 2025 D ALPAP+Y Y APAG VE+ +A ++A+VLGL RVGV +SFF+LGGDSL+AMR+ Sbjct 3480 DTGALPAPDYQGPEDYLAPAGAVEEILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRL 3539 Query 2026 IAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPR--LVSVHGDNPTEVHASDL 2083 +AAI L+ LPVRA+ A S R LSQ L D R SVHG + TEV+ASDL Sbjct 3540 VAAIYNALDIHLPVRAVFEAPSVRSLSQRLNADPAVAQGLRADFASVHGRDATEVYASDL 3599 Query 2084 TLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDV-DGRLICLVR 2142 TLD+FIDA TL+ A LPGP E+RTVLLTGATGFLGRYLVL+ L RL++ DG+LICLVR Sbjct 3600 TLDKFIDAATLSAAPALPGPGAEVRTVLLTGATGFLGRYLVLQWLERLELADGKLICLVR 3659 Query 2143 AESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETV 2202 A SD+DARRRLE+TFDSGDP LLR+F ELAAD LEV+AGDK +LGLD W+RLA+TV Sbjct 3660 AASDDDARRRLERTFDSGDPALLRYFHELAADHLEVIAGDKGRANLGLDDRTWQRLADTV 3719 Query 2203 DLIVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFT 2261 DLIVD+AA+VN PY ELFGPNVAGTAELIR+AL+T+LKP++YVSTA+VG IEPSAFT Sbjct 3720 DLIVDAAAVVNGVLPYQELFGPNVAGTAELIRLALSTRLKPYSYVSTANVGDQIEPSAFT 3779 Query 2262 EDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAG 2321 EDADIRV P RT+DGG+ GYG SKWAGEVLLREA+DLC LPV+VFRC MILADTSYAG Sbjct 3780 EDADIRVAGPIRTIDGGYGNGYGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTSYAG 3839 Query 2322 QLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAG 2381 QLN+SD TR++ S++A+G+APRSFY D+ GNRQRAHFD LPV FVAEAIA LGA+V Sbjct 3840 QLNLSDMFTRLLFSVVASGVAPRSFYRLDAHGNRQRAHFDALPVEFVAEAIATLGAQVGR 3899 Query 2382 SSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQR 2441 + GFATYHVMNPHDDGIGLDEYVDWLIEAGY I R+DDF +WL R E +L ALP+RQR Sbjct 3900 DAGIGFATYHVMNPHDDGIGLDEYVDWLIEAGYLIERVDDFDQWLHRMETALHALPERQR 3959 Query 2442 RHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIIN 2501 SVL +L ++ + P P RGC PT+RFRAAV+ AK+G+D DIPH++AP I+ Sbjct 3960 HQSVLQLLALRKARHVPPADPARGCLGPTERFRAAVQEAKIGADN---DIPHITAPVIVK 4016 Query 2502 YVTNLQLLGLL 2512 YVT+LQLLGLL Sbjct 4017 YVTDLQLLGLL 4027 Score = 822 bits (2124), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/1027 (50%), Positives = 635/1027 (62%), Gaps = 63/1027 (6%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV-----IEARRAD 1098 VY + +++ LRG LD L A+ VV RH +L F G P Q++ + R + Sbjct 1533 VYAVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQIIPAEPEMAWRYLE 1592 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L +D ++L++ + +L P L R AD EH V HH+ D Sbjct 1593 LDGGDID------EQLEQLSADERAAVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMD 1646 Query 1159 GWSVAPLTADLSAAY-ASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLA 1217 GWS+ L ++ A Y +R P P Y + W L D P A A Sbjct 1647 GWSLPVLLQEIFACYYGARL--------PAPAPYRGFVTW-------LAARDVPAAR--A 1689 Query 1218 YWENALAGMPERLRLPTARPYPPVADQRGASLVVDW--PASVQQQVRRIARQHNATSFMV 1275 W L G PT P AD G V + A V +AR+ T V Sbjct 1690 AWRAVLDG----FDTPTLVA-PRGADAPGRRGVASFRVAAETTSAVSELARRRRTTVNTV 1744 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGDPSFAEL 1333 + A A LL L+G DVA G ++GR P +++VG +NT+ +R + + A+L Sbjct 1745 LQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRAHATAATTIADL 1804 Query 1334 LGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLG---DL 1390 + Q++ E+Q + + R L +L +++ P+ L DL Sbjct 1805 VDQLQRAHNHTVEHQHLALNEI------HRITGQDQLFDTLLVYENYPIDTAALSAADDL 1858 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 AT + L+ + G E +G +E+ TDVF+ AID L +RLRK+L Sbjct 1859 TATEFSCHDYNH-----YPLSLQVVPGDE---LGLRLEFDTDVFDPAAIDTLADRLRKLL 1910 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 A+ A P+R + S+D LD TE RL WGNR L+ PA P S+P++ AAQVA P A A Sbjct 1911 AAMPADPDRPLRSLDLLDATEHTRLQRWGNRPALSRPATGP-SLPELFAAQVANAPHAVA 1969 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 + SMTYRELDEAS RLAH LAG GA PG VALLF R A A+VAM+AVLKTGAAYL Sbjct 1970 LRYAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYL 2029 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAA 1630 PIDPA P R+ FMLGDA PV AV+TA LR+RL LP++DV A A PG P P PA Sbjct 2030 PIDPALPATRIEFMLGDAAPVVAVSTADLRARLEAFGLPVVDVA-ATGAQPGGPLPAPAP 2088 Query 1631 VNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 N+AY+LYTSGTTG PKGV +THRNV +L SL A L VWSQCHSYGFD S EIWG Sbjct 2089 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWSQCHSYGFDVSVQEIWG 2148 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 AL GGGRLV+VPESV +SP++ H LL+AE+V+VL+QTP+A+A L + L + ALV+ GE Sbjct 2149 ALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHA-ALVIGGEP 2207 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CPAAL DRWAPGRVM+NAYGPTETT+ A +S PL G+G PP+G PV+GA LFVLD+WLR Sbjct 2208 CPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDAWLR 2267 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 VPAGV GELYIAGAGV GY R GLTA+RFVACPFG +GARMYRTGDLV W DG+L Sbjct 2268 QVPAGVTGELYIAGAGVAAGYLGRPGLTAARFVACPFGDAGARMYRTGDLVRWDRDGRLH 2327 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 ++ R D QVKIRG+RIELGE+ +ALAEL GVG+ VIAREDRPG+KR+VGY T G Sbjct 2328 YVARADQQVKIRGHRIELGEIHSALAELDGVGEVAVIAREDRPGEKRIVGYLT----GTA 2383 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DPA +RA+LA+RLP Y+VPAAV+ I+ALPLT NGKLD RALPAPEY YRAP+ P E Sbjct 2384 DPAAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAG-GAYRAPSTPTE 2442 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 + +AGI+ +VLGL RVGVDDSFF+LGGDSL+AMRVIAA+N L+A L VR L A + Sbjct 2443 EIIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQ 2502 Query 2051 LSQLLGR 2057 L+ LG Sbjct 2503 LAARLGE 2509 Score = 781 bits (2017), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/1031 (47%), Positives = 611/1031 (60%), Gaps = 75/1031 (7%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A PL+ Q +W + + + + +++ G + +AL A+ V E R F Sbjct 15 AFPLTRGQLDIWLSQEAGFAGTQWQLGLLVKIDGKVHRDALEQAITQAVAEAEPGRVSFF 74 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRI 1141 +DG Q I+ +L + A P + R L ++ + LF+ Sbjct 75 ELDGQVVQKPIDYPHVELAFHDLTDHADPVAEAREMSSAIQRTPMPLNGQM-FKFVLFQT 133 Query 1142 ADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREI 1201 DE L HHIA DG +A + ++ Y++ AG+ P+P Y + Sbjct 134 GHDEFYLFGCCHHIAIDGLGMALVCRRVATIYSAMVAGK-----PIPDAYFGTV----QD 184 Query 1202 LGDLD---DSDSPIAAQLAYWENALAGMPERL---RLPTARPYPPVADQRGASLVVDWPA 1255 L DL+ ++ A AYW L PE RLP A D S V Sbjct 185 LIDLESGYEASPDYAEDKAYWSEHLP--PESGPVDRLPDAEGE---RDHYSPSASVQLDP 239 Query 1256 SVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGS-PDVAVGFPIAGRSDPALDNLVGFF 1314 SV +++ ++++ F V A A+L+ SGS +VA+ FP++ R P L Sbjct 240 SVANRIKELSKKLAIRRFSVTTAACALLVRGWSGSGSEVALDFPVSRRVRPESKTLPAML 299 Query 1315 VNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVM 1374 + L ++ A + + A+ V R I+ + Sbjct 300 AGVVPLVLSTAPESTVADFCKHVDKR------------------------------IREL 329 Query 1375 LAWQDNPVGQLNLGDLQATP--MPIDTRTARM--DLVFSLAERFSEGSEPAG------IG 1424 LA Q PV L L+ P + I+ +R+ DL S A P G +G Sbjct 330 LAHQRFPVHTLEGDGLRQAPNRVGINFIPSRLTLDLAGSPATASYTNHGPVGHFGLFFLG 389 Query 1425 GAVEYRTDV------FEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEW 1478 + F + + L RL+++L A+ P+R +SSI+ L G E A +D W Sbjct 390 AGDQLFLSTAGPGQPFASFGVADLAGRLQQILAAMTEDPDRPLSSIELLTGDEPALIDRW 449 Query 1479 GNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCG 1538 NR LT PAP PVSIPQ A V R P+A AV G S+TY +LDEASNRL H LA G Sbjct 450 SNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAVTFGATSLTYAQLDEASNRLGHLLADHG 509 Query 1539 AGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAG 1598 GPG+CVA++F RCA A+V+M+AVLKTGAAY+PIDPA+ R+ F+L DA P A +TT+ Sbjct 510 VGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADAAPSAVITTSD 569 Query 1599 LRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVT 1657 LRSRL HDL ++DV D A+ A PGT P PA + AYI+YTSGTTG PKGV I H NVT Sbjct 570 LRSRLDDHDLLVVDVHDPAVEAQPGTALPWPAPEDTAYIIYTSGTTGTPKGVAIPHLNVT 629 Query 1658 RLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLV 1717 L SL A L VW+QCHS FD S WEI+GALL G RL++VPESVA+SP DFH LLV Sbjct 630 WLIESLDAGLPPGNVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESVASSPEDFHALLV 689 Query 1718 AEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWA-PGRVMLNAYGPTETTI 1776 AE VSVLTQTP+AVAML +GLES ALVVAGEACP +VDRWA PGRVML+AYGPTETT+ Sbjct 690 AEQVSVLTQTPSAVAMLSPEGLESTALVVAGEACPTDVVDRWAAPGRVMLDAYGPTETTV 749 Query 1777 CAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAG 1836 CA+IS PL G + PIG P++GAA+FVLD WL+PVPAGV GELY+AG GVG GY RR G Sbjct 750 CASISTPLTAGDPVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAGRGVGHGYVRRPG 809 Query 1837 LTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALA 1896 LTASRFV PFG G+RMYRTGDLVCW DGQL++LGR D+QVKIRG+RIELGE + LA Sbjct 810 LTASRFVPNPFGAPGSRMYRTGDLVCWGPDGQLQYLGRADEQVKIRGFRIELGETQSVLA 869 Query 1897 ELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVID 1956 L GV QA V+AREDRPGDKRLVGY T G DPA LRAQLA RLP Y+VP AV+V+D Sbjct 870 GLDGVEQAAVVAREDRPGDKRLVGYIT----GTADPAELRAQLADRLPPYMVPTAVMVLD 925 Query 1957 ALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELG 2016 ALPLT NGKLD RALP+PEY YRAP +E+ +A I+A+VLG+ERVGVDDSFF+LG Sbjct 926 ALPLTGNGKLDKRALPSPEYA-AGEYRAPGDAIEEILADIYAQVLGVERVGVDDSFFDLG 984 Query 2017 GDSLAAMRVIA 2027 GDS+ +M+V+A Sbjct 985 GDSILSMQVVA 995 Score = 97.4 bits (241), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 141/527 (27%), Positives = 212/527 (41%), Gaps = 60/527 (11%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L G PGD + I ++A G Y D A S + + + Sbjct 505 LADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADAAPSAV 564 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLA----TKTAYIMPTSGTTGQPKLV 590 +T D+ + + HD L V + + L TAYI+ TSGTTG PK V Sbjct 565 ITTSDLRSR---LDDHDLLVVDVHDPAVEAQPGTALPWPAPEDTAYIIYTSGTTGTPKGV 621 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAM 647 I H ++ +++ G + QC D SV EIFG G RL+ S A Sbjct 622 AIPHLNVTWLIESLDAGLPPG--NVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESVAS 679 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 D AL LVA + +++ + +L +G A+ V+ GEA V Sbjct 680 SPEDFHAL---LVAEQVSVLTQTPSAVAMLSPEGLESTAL--------VVAGEACPTDVV 728 Query 708 DKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL--- 764 D+W A+ G +L +YGPTE TV A+ + T ++ +G PI +F+ Sbjct 729 DRW----AAPGRVMLDAYGPTETTVCAS----ISTPLTAGDPVVPIGSPIAGAAMFVLDK 780 Query 765 --------AFGEVVIVGDLVADGYL---GIDGDGF-GTVTAADGSRRRAFATGDRVTVDA 812 GE+ + G V GY+ G+ F A GSR + TGD V Sbjct 781 WLQPVPAGVVGELYLAGRGVGHGYVRRPGLTASRFVPNPFGAPGSR--MYRTGDLVCWGP 838 Query 813 EGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQR 868 +G + GR D VKI G R+++ E +A V AV G V + + Sbjct 839 DGQLQYLGRADEQVKIRGFRIELGETQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGT 898 Query 869 TREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNT 928 E A A R+ +V V+ + +P NGK+D LP P++ AAG Sbjct 899 ADPAELRAQLADRLPPYMVPTA-----VMVLDALPLTGNGKLDKRALPS-PEY-AAGEYR 951 Query 929 AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 A L+ I+++ LG +G D S G S+ ++++ R Sbjct 952 APGDAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARAR 998 >gi|289764218|ref|ZP_06523596.1| PstD [Mycobacterium tuberculosis GM 1503] gi|289711724|gb|EFD75740.1| PstD [Mycobacterium tuberculosis GM 1503] Length=972 Score = 1884 bits (4880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 943/947 (99%), Positives = 943/947 (99%), Gaps = 0/947 (0%) Query 1566 GAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPP 1625 G L IDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPP Sbjct 26 GGRILRIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPP 85 Query 1626 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASA 1685 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASA Sbjct 86 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASA 145 Query 1686 WEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALV 1745 WEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALV Sbjct 146 WEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALV 205 Query 1746 VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVL 1805 VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVL Sbjct 206 VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVL 265 Query 1806 DSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRA 1865 DSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRA Sbjct 266 DSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRA 325 Query 1866 DGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEI 1925 DGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEI Sbjct 326 DGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEI 385 Query 1926 APGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAP 1985 APGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAP Sbjct 386 APGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAP 445 Query 1986 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHA 2045 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHA Sbjct 446 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHA 505 Query 2046 SSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSP 2105 SSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSP Sbjct 506 SSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSP 565 Query 2106 ELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELL 2165 ELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELL Sbjct 566 ELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPELL 625 Query 2166 RHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNV 2225 RHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNV Sbjct 626 RHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNV 685 Query 2226 AGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGT 2285 AGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGT Sbjct 686 AGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGT 745 Query 2286 SKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRS 2345 SKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRS Sbjct 746 SKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRS 805 Query 2346 FYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEY 2405 FYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEY Sbjct 806 FYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEY 865 Query 2406 VDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRG 2465 VDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRG Sbjct 866 VDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRG 925 Query 2466 CSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 CSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Sbjct 926 CSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 972 Score = 99.8 bits (247), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 146/512 (29%), Positives = 208/512 (41%), Gaps = 60/512 (11%) Query 530 GDGILVTVVDVAATQLAVVGHD-ELRKVVDERVTQVTHDALL--ATKTAYIMPTSGTTGQ 586 GD + V V A + + GHD + VVD + A AYI+ TSGTTG+ Sbjct 46 GDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGE 105 Query 587 PKLVRISHGS----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV 642 PK V I+H + A +S A W QC D S EI+G G RLV Sbjct 106 PKGVGITHRNVTRLFASLPARLSAAQVWS------QCHSYGFDASAWEIWGALLGGGRLV 159 Query 643 ---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGG 699 S A D L LVA +++ A +L G ++++ +V+ G Sbjct 160 IVPESVAASPNDFHGL---LVAEHVSVLTQTPAAVAMLPTQG--LESVA------LVVAG 208 Query 700 EAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM--------DGALL 751 EA + VD+W + G +L++YGPTE T+ A + + M AL Sbjct 209 EACPAALVDRW-----APGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALF 263 Query 752 RLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRV 808 L + P +A GE+ I G V GY G+ F GS R + TGD V Sbjct 264 VLDSWLRPVPAGVA-GELYIAGAGVGVGYWRRAGLTASRF-VACPFGGSGARMYRTGDLV 321 Query 809 TVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSD---VAVELHSGSLGVWFK 865 A+G F GR D VKI G R+++ EV +AE V +A E G + Sbjct 322 CWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGY 381 Query 866 SQRTREGEQDAAA-----ATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQ 920 + G D A A R+ LV VV + +P NGK+D LP P+ Sbjct 382 ATEIAPGAVDPAGLRAQLAQRLPGYLVPAA-----VVVIDALPLTVNGKLDHRALP-APE 435 Query 921 WSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW 979 + A G ++ I++R LG +G D S G SL +R++ L Sbjct 436 YGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNA 495 Query 980 RLSLLDLIGADTAANLADYAPTPDAPTGEDRF 1011 L + L+ A + L+ PT + R Sbjct 496 DLPVRALLHASSTRGLSQLLGRDARPTSDPRL 527 >gi|339293167|gb|AEJ45278.1| peptide synthetase, putative [Mycobacterium tuberculosis CCDC5079] Length=886 Score = 1649 bits (4271), Expect = 0.0, Method: Compositional matrix adjust. Identities = 837/838 (99%), Positives = 838/838 (100%), Gaps = 0/838 (0%) Query 1 VHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 +HRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL Sbjct 1 MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLAALHATVLDNPVQLCVL 60 Query 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV Sbjct 61 ENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPLVRHTVHTDPNGYVTGLDV 120 Query 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS Sbjct 121 HTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAKLREAHRRETAKVEESRGRLS 180 Query 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL Sbjct 181 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNVL 240 Query 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR Sbjct 241 VAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVATCLVNSVAQTVRFPPFASVSDVVR 300 Query 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT Sbjct 301 TLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAPGLRPFLSEVPIAT 360 Query 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA Sbjct 361 DIGPVEGMTVASVLDEEQRTLNLAIWNRADLPACKTHPKVAERIAAALESMAAMWDRPIA 420 Query 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA Sbjct 421 MIVNDWFGIGPDGTRCQGDWPARQPSTPAWFLDSARGVHQFLGRRRFVYPWVAWLVQRGA 480 Query 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV Sbjct 481 APGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVVDV 540 Query 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF Sbjct 541 AATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVF 600 Query 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV Sbjct 601 CDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLV 660 Query 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS Sbjct 661 ARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGIS 720 Query 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY Sbjct 721 LLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGY 780 Query 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEV 838 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEV Sbjct 781 LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEV 838 Score = 87.0 bits (214), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 111/381 (30%), Positives = 158/381 (42%), Gaps = 48/381 (12%) Query 1538 GAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFML---GDAVPVAAV 1594 GA PG+ + + + ++A G Y D A+ + GD + V V Sbjct 479 GAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVV 538 Query 1595 TTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHR 1654 A + + GHD + VVD + A AYI+ TSGTTG+PK V I+H Sbjct 539 DVAATQLAVVGHD-ELRKVVDERVTQVTHDALL--ATKTAYIMPTSGTTGQPKLVRISHG 595 Query 1655 NVTRLFASLPARLSAAQVWS------QCHSYGFDASAWEIWGALLGGGRLVIVPESVAAS 1708 + A +S A W QC D S EI+G G RLV S A Sbjct 596 S----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAMK 648 Query 1709 PNDFHGL---LVAEHVSVLTQTPAAVAMLPTQG--LESVA------LVVAGEACPAALVD 1757 D L LVA +++ A +L G ++++ +V+ GEA + VD Sbjct 649 TGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVD 708 Query 1758 RW-----APGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 +W + G +L++YGPTE T+ A + + M AL L + P Sbjct 709 KWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMD--------GALLRLGRPILPN 760 Query 1813 PAGVA-GELYIAGAGVGVGYWRRAGLTASRF-VACPFGGSGARMYRTGDLVCWRADGQLE 1870 +A GE+ I G V GY G+ F GS R + TGD V A+G Sbjct 761 TVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPV 817 Query 1871 FLGRTDDQVKIRGYRIELGEV 1891 F GR D VKI G R+++ EV Sbjct 818 FSGRKDAVVKISGKRVDIAEV 838 >gi|254775689|ref|ZP_05217205.1| linear gramicidin synthetase subunit B [Mycobacterium avium subsp. avium ATCC 25291] Length=2552 Score = 1511 bits (3913), Expect = 0.0, Method: Compositional matrix adjust. Identities = 858/1511 (57%), Positives = 1031/1511 (69%), Gaps = 71/1511 (4%) Query 1023 IPLSFAQRRLWFLDQL-QRPAP-VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F Q P VY + + + + G LD+ L AV VV RH +L F Sbjct 1092 LPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGALDSHRLHDAVHTVVNRHPNLAARF 1151 Query 1081 PAVDGVPRQLV-----IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+V + R LG + VD P +++ DLA R Sbjct 1152 CPQYGEPVQVVPADPVMAWRYIQLGPEDVD----PEQKVEELCAAERAAVSDLANRPAFR 1207 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R AD+ H V HHI DGWS+ L ++ A Y D P P Y Y Sbjct 1208 AALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYG-------DQLPAPATYRSYL 1260 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVD--- 1252 W L D S AAQ A W L G T P R V+ Sbjct 1261 TW----LAGQDRS----AAQAA-WRQVLDG------FDTPTLVGPAGRMRLGRRAVESYR 1305 Query 1253 WPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNL 1310 A + + +AR + T V+ AG A LL +L+G DVA G ++GR +D A +++ Sbjct 1306 LSAETTRALGELARACHTTVNTVLQAGWAQLLMRLTGQHDVAFGTAVSGRPADLAGAESM 1365 Query 1311 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL 1370 VG +NT+ +R N + + A+LL Q++ E++ + + R H L Sbjct 1366 VGLLINTVPVRANTHAETTVADLLDQLQQHHNDTLEHEHLALSEI------HRVTGHDAL 1419 Query 1371 IQVMLAWQDNPVG-QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 + +++ P+ + LG + + I T R + L+ G E +G VE+ Sbjct 1420 FDTLFLYENYPIDTSVPLGFHE---LAITDVTNREYNHYPLSVMALPGRE---LGLRVEF 1473 Query 1430 RTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAP 1489 TDVF+A I+ L ER ++VL + A P R ++S++ +D E LD WGNR VL+ PA Sbjct 1474 DTDVFDAAGIEKLTERFQRVLSEMTADPTRRLTSLEVMDEAEHELLDAWGNRPVLSQPA- 1532 Query 1490 TPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLF 1549 T SIP + AAQVAR P+A A+ SM+YRELDEASNRLAH L GAGPGECVALLF Sbjct 1533 TGTSIPALFAAQVARTPDAAALTFQGRSMSYRELDEASNRLAHLLIEEGAGPGECVALLF 1592 Query 1550 ERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLP 1609 R A A+V+++AVLKTGAAYLPIDPA P R+ F+LGDA PVA VTTA LRSRL G Sbjct 1593 SRSAEAIVSILAVLKTGAAYLPIDPALPAARIEFLLGDAEPVAVVTTAALRSRLDGCKPS 1652 Query 1610 IIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS 1668 ++DV D ALA P P+P++ N+AY++YTSGTTG PKGV ++H NV +L SL A L Sbjct 1653 VVDVDDPALAGQPSAALPVPSSDNIAYLIYTSGTTGVPKGVAVSHDNVAQLVESLHADLP 1712 Query 1669 AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 VW+Q HS FD S EIWGALL GGRLV+VPESVAASP++ H LLVAE V+VL+QTP Sbjct 1713 EGGVWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHDLLVAEGVTVLSQTP 1772 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 +AV ML +GL+S ALVVAGEACP +VDRWAPGRVM+NAYGPTE T+ AA+S PL+PG+ Sbjct 1773 SAVGMLSPEGLDSTALVVAGEACPVEIVDRWAPGRVMINAYGPTEATVYAAMSTPLQPGT 1832 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 G PIG PV AALFVLD WLRP P GV GELYIAG GV GY RR+GLTASRFVACPFG Sbjct 1833 GSAPIGSPVPRAALFVLDRWLRPAPPGVVGELYIAGHGVATGYARRSGLTASRFVACPFG 1892 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 G GARMYRTGDLV W DGQLE+LGR D+QVK+RGYRIELGEV ALA L GV QA VIA Sbjct 1893 GPGARMYRTGDLVRWNQDGQLEYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIA 1952 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 REDRPGDKRLVGY T G DP G+R QLA+RLP Y+VPAAVVV+DALPLTVNGKLD Sbjct 1953 REDRPGDKRLVGYIT----GTADPVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDK 2008 Query 1969 RALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 RALPAPEY G Y AP P E+TVAGIFARVLG+ERV +DDSFFELGGDSL+AMRVIA Sbjct 2009 RALPAPEYRKRGGEYIAPTNPTEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIA 2068 Query 2028 AINTTLNADLPVRALLHASSTRGLSQLL--GRDARPTSDPRLVSVHGDNPTEVHASDLTL 2085 INT ++ L VR L + S R LSQ + G DA + P +VHG + EV+A DLTL Sbjct 2069 EINTAVDGALSVRTLFDSQSVRALSQRITSGADAENAAGPGFAAVHGADAKEVYARDLTL 2128 Query 2086 DRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAE 2144 D+F+DA TL+TA LPGPSPE+RTVLLTGATGFLGRYLVLE L +L+ VDG+LICLVRA Sbjct 2129 DKFLDATTLSTAPTLPGPSPEVRTVLLTGATGFLGRYLVLEWLEQLEQVDGKLICLVRAR 2188 Query 2145 SDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDL 2204 SDE+A RLEKTF++GDPELLRHF+ELA + L+VVAGDK + +LGLD+ W++LA+TVDL Sbjct 2189 SDEEAWGRLEKTFNTGDPELLRHFQELAEEHLQVVAGDKGQANLGLDEQTWQQLADTVDL 2248 Query 2205 IVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTED 2263 IVDSAA+VN PY ELF PNV GTAELIR+ALTT+ KPF YVST+DVG IEPSAFTED Sbjct 2249 IVDSAAVVNGVLPYSELFTPNVGGTAELIRLALTTRKKPFAYVSTSDVGRQIEPSAFTED 2308 Query 2264 ADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQL 2323 ADIRVIS TR +DG +A GYG SKWAGEVLLREA+DLC LPV+VFR MILADTSYAGQL Sbjct 2309 ADIRVISATRVIDGSYANGYGNSKWAGEVLLREAHDLCGLPVSVFRSDMILADTSYAGQL 2368 Query 2324 NMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSS 2383 N++D TRM+LS++ATG AP+SFY D++GNRQR+HFD LPV FVAEAIA LGA+V Sbjct 2369 NVTDIFTRMILSIVATGTAPKSFYRLDADGNRQRSHFDALPVEFVAEAIAKLGAQV---- 2424 Query 2384 LAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRH 2443 + GF TYHVMNPHDDGIGLDEYVDWLIEAGYPI R+DDF EWLQRFE L LP+RQR++ Sbjct 2425 MDGFETYHVMNPHDDGIGLDEYVDWLIEAGYPIERVDDFGEWLQRFETGLRGLPERQRQN 2484 Query 2444 SVLPMLLAS--NSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIIN 2501 SVL MLL + + LQP +P RG APTDRFRAAV+ AKVGSD DIPH+SAP I+ Sbjct 2485 SVLQMLLLLLRDPKNLQPAEPARGAFAPTDRFRAAVQEAKVGSDN---DIPHISAPVIVK 2541 Query 2502 YVTNLQLLGLL 2512 YVT+LQLLGLL Sbjct 2542 YVTDLQLLGLL 2552 Score = 763 bits (1970), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/576 (69%), Positives = 449/576 (78%), Gaps = 11/576 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R + SID LDG E RLDEWGNRA+LT P P SIP M AAQVAR EA A+ SM Sbjct 7 RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAPASIPGMFAAQVARSAEAVALSFEGRSM 66 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TYRELDEASNRLAH LA GA PGECVALLF R A+V+++AVLKTGAAYLPIDPA P Sbjct 67 TYRELDEASNRLAHLLAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPA 126 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPP----PMPAAVNLA 1634 R+ FMLGDA P+AAVTTAGLR RL G DLP+IDV +A A T P P P+ ++A Sbjct 127 ARMEFMLGDATPIAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIA 186 Query 1635 YILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA--QVWSQCHSYGFDASAWEIWGAL 1692 Y++YTSGTTG PKGV +THRNVT +L +L + QVWSQ HS FD S WE WGAL Sbjct 187 YMIYTSGTTGTPKGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGAL 246 Query 1693 LGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACP 1752 L GGRLV+VPESVA SP+D H LLVAE V+VL+QTP+AV ML +GL+S ALVVAGEACP Sbjct 247 LHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACP 306 Query 1753 AALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 A +VDRWAPGRVM+NAYGPTE T+ AA+SAPL SG PPIG PV GAALFVLD WLRP Sbjct 307 AEVVDRWAPGRVMINAYGPTEATVYAAMSAPLTAESGAPPIGSPVPGAALFVLDKWLRPA 366 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELYIAG GV GY RRAGLTASRFVACPFGG GARMYRTGDLV W ADGQL++L Sbjct 367 PEGVVGELYIAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWGADGQLQYL 426 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLVGY T G DP Sbjct 427 GRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYIT----GTADP 482 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEK 1991 A LR QL +RLP Y+VPAAVVV+++LPLTVNGKLD RALPAPEY G YRAP+ E+ Sbjct 483 AELRTQLGKRLPAYMVPAAVVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRAPSNHTEE 542 Query 1992 TVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +A I+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 543 ILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 578 Score = 108 bits (269), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 180/734 (25%), Positives = 284/734 (39%), Gaps = 74/734 (10%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L ++GAAPG+ + +D+ I ++A G Y D A + + GD Sbjct 82 LAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPAARMEFML---GDATP 138 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLAT-------KTAYIMPTSGTTGQP 587 + V A + + G D VDE ++ + AY++ TSGTTG P Sbjct 139 IAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIAYMIYTSGTTGTP 198 Query 588 KLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAM 647 K V ++H ++ F + G Q L D+SV E +G G RLV Sbjct 199 KGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGALLHGGRLVVVPES 258 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 G L D LVA T++ + +L +G +D+ +V+ GEA V Sbjct 259 VAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEG--LDSTA------LVVAGEACPAEVV 310 Query 708 DKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL--- 764 D+W + G ++++YGPTEATV A + T + +G P+ +F+ Sbjct 311 DRW-----APGRVMINAYGPTEATVYAA----MSAPLTAESGAPPIGSPVPGAALFVLDK 361 Query 765 --------AFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE 813 GE+ I G VA GY G+ F G R + TGD V A+ Sbjct 362 WLRPAPEGVVGELYIAGRGVATGYARRAGLTASRF-VACPFGGPGARMYRTGDLVRWGAD 420 Query 814 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRT 869 G + GR D VKI G R+++ E+ +A V AV G V + + Sbjct 421 GQLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTA 480 Query 870 REGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTA 929 E R+ +V VV + ++P NGK+D LP AG A Sbjct 481 DPAELRTQLGKRLPAYMVPAA-----VVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRA 535 Query 930 ETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIG 988 + L+ I+++ LG +G D S G S+ ++++ R G D+ Sbjct 536 PSNHTEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGVICRPRDVFV 594 Query 989 ADTAANLADYAPTPDAPTGEDRFRPLVAAQRPA-AIPLSFAQRRLWFLDQLQRPAPVYNM 1047 T A LA A G D + + P A P+ + +L +Q P +N Sbjct 595 EQTVARLARV-----ASDGADEEQVVDEGIGPVQATPI------MRWLQTVQGPIDDFNQ 643 Query 1048 AVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDAT 1107 + L + + + + ++ RH LR L + D + + Sbjct 644 TMVLAAPSGVTADDVAVVLQALLDRHPMLRLRVEDDGAGGWNLQAPEPGSVRAADCLQSV 703 Query 1108 AWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAVAHHIAADGWSVAPLT 1166 D L A+ AAR + + + W A + L + HH+A DG S L Sbjct 704 ----DTLSDAVLVAARSRLNPGAGVMVSAVW----ASETSQLALIIHHVAVDGVSWRTLI 755 Query 1167 ADLSAAYASRCAGR 1180 DL+ A+A +G+ Sbjct 756 EDLNIAWAQHHSGQ 769 Score = 96.3 bits (238), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 148/544 (28%), Positives = 218/544 (41%), Gaps = 49/544 (9%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L++ GA PG+ + + + I ++A G Y D A + R + GD Sbjct 1577 LIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALP-AARIEFLL--GDAEP 1633 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALL----ATKTAYIMPTSGTTGQPKLV 590 V VV AA + + G VD+ A L + AY++ TSGTTG PK V Sbjct 1634 VAVVTTAALRSRLDGCKPSVVDVDDPALAGQPSAALPVPSSDNIAYLIYTSGTTGVPKGV 1693 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTG 650 +SH ++A +++ G Q L D+SV EI+G G RLV Sbjct 1694 AVSHDNVAQLVESLHADLPEGG--VWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAA 1751 Query 651 DLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKW 710 L D LVA T++ + +L +G +D+ +V+ GEA VD+W Sbjct 1752 SPDELHDLLVAEGVTVLSQTPSAVGMLSPEG--LDSTA------LVVAGEACPVEIVDRW 1803 Query 711 LESAASQGISLLSSYGPTEATVVATFLPIVCDQT--------TMDGALL---RLGRPILP 759 + G ++++YGPTEATV A + T AL R RP P Sbjct 1804 -----APGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPP 1858 Query 760 NTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFP 816 V GE+ I G VA GY G+ F G R + TGD V + +G Sbjct 1859 GVV----GELYIAGHGVATGYARRSGLTASRF-VACPFGGPGARMYRTGDLVRWNQDGQL 1913 Query 817 VFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDA 876 + GR D VK+ G R+++ EV +A V AV G +R Sbjct 1914 EYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPG----DKRLVGYITGT 1969 Query 877 AAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ 933 A IR+ L + VV + +P NGK+D LP G A T Sbjct 1970 ADPVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNP 2029 Query 934 RAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTA 992 ++ I++R LG + D S G SL +R++ E + LS+ L + + Sbjct 2030 TEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIAEINTAVDGALSVRTLFDSQSV 2089 Query 993 ANLA 996 L+ Sbjct 2090 RALS 2093 >gi|5524341|gb|AAD44234.1|AF143772_40 PstB [Mycobacterium avium] Length=2552 Score = 1509 bits (3908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 857/1511 (57%), Positives = 1030/1511 (69%), Gaps = 71/1511 (4%) Query 1023 IPLSFAQRRLWFLDQL-QRPAP-VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F Q P VY + + + + G LD+ L AV VV RH +L F Sbjct 1092 LPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGALDSHRLHDAVHTVVNRHPNLAARF 1151 Query 1081 PAVDGVPRQLV-----IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+V + R LG + VD P +++ DLA R Sbjct 1152 CPQYGEPVQVVPADPVMAWRYIQLGPEDVD----PEQKVEELCAAERAAVSDLANRPAFR 1207 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R AD+ H V HHI DGWS+ L ++ A Y D P P Y Y Sbjct 1208 AALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYG-------DQLPAPATYRSYL 1260 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVD--- 1252 W L D S AAQ A W L G T P R V+ Sbjct 1261 TW----LAGQDRS----AAQAA-WRQVLDG------FDTPTLVGPAGRMRLGRRAVESYR 1305 Query 1253 WPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNL 1310 A + + +AR + T V+ AG A LL +L+G DVA G ++GR +D A +++ Sbjct 1306 LSAETTRALGELARACHTTVNTVLQAGWAQLLMRLTGQHDVAFGTAVSGRPADLAGAESM 1365 Query 1311 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL 1370 VG +NT+ +R N + + A+LL Q++ E++ + + R H L Sbjct 1366 VGLLINTVPVRANTHAETTVADLLDQLQQHHNDTLEHEHLALSEI------HRVTGHDAL 1419 Query 1371 IQVMLAWQDNPVG-QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 + +++ P+ + LG + + I T R + L+ G E +G VE+ Sbjct 1420 FDTLFLYENYPIDTSVPLGFHE---LAITDVTNREYNHYPLSVMALPGRE---LGLRVEF 1473 Query 1430 RTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAP 1489 TDVF+A I+ L ER ++VL + A P R ++S++ +D E LD WGNR VL+ PA Sbjct 1474 DTDVFDAAGIEKLTERFQRVLSEMTADPTRRLTSLEVMDEAEHELLDAWGNRPVLSQPA- 1532 Query 1490 TPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLF 1549 T SIP + AAQVAR P+A A+ SM+YRELDEASNRLAH L GAGPGECVALLF Sbjct 1533 TGTSIPALFAAQVARTPDAAALTFQGRSMSYRELDEASNRLAHLLIEEGAGPGECVALLF 1592 Query 1550 ERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLP 1609 R A A+V+++AVLKTGAAYLPIDPA P R+ F+LGDA PVA VTTA LRSRL G Sbjct 1593 SRSAEAIVSILAVLKTGAAYLPIDPALPAARIEFLLGDAEPVAVVTTAALRSRLDGCKPS 1652 Query 1610 IIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS 1668 ++DV D AL P P+P++ N+AY++YTSGTTG PKGV ++H NV +L SL A L Sbjct 1653 VVDVDDPALDGQPSAALPVPSSDNIAYLIYTSGTTGVPKGVAVSHDNVAQLVESLHADLP 1712 Query 1669 AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 VW+Q HS FD S EIWGALL GGRLV+VPESVAASP++ H LLVAE V+VL+QTP Sbjct 1713 EGGVWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHDLLVAEGVTVLSQTP 1772 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 +AV ML +GL+S ALVVAGEACP +VDRWAPGRVM+NAYGPTE T+ AA+S PL+PG+ Sbjct 1773 SAVGMLSPEGLDSTALVVAGEACPVEIVDRWAPGRVMINAYGPTEATVYAAMSTPLQPGT 1832 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 G PIG PV AALFVLD WLRP P GV GELYIAG GV GY RR+GLTASRFVACPFG Sbjct 1833 GSAPIGSPVPRAALFVLDRWLRPAPPGVVGELYIAGHGVATGYARRSGLTASRFVACPFG 1892 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 G GARMYRTGDLV W DGQLE+LGR D+QVK+RGYRIELGEV ALA L GV QA VIA Sbjct 1893 GPGARMYRTGDLVRWNQDGQLEYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIA 1952 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 REDRPGDKRLVGY T G DP G+R QLA+RLP Y+VPAAVVV+DALPLTVNGKLD Sbjct 1953 REDRPGDKRLVGYIT----GTADPVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDK 2008 Query 1969 RALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 RALPAPEY G Y AP P E+TVAGIFARVLG+ERV +DDSFFELGGDSL+AMRVIA Sbjct 2009 RALPAPEYRKRGGEYIAPTNPTEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIA 2068 Query 2028 AINTTLNADLPVRALLHASSTRGLSQLL--GRDARPTSDPRLVSVHGDNPTEVHASDLTL 2085 INT ++ L VR L + S R LSQ + G DA + P +VHG + EV+A DLTL Sbjct 2069 EINTAVDGALSVRTLFDSQSVRALSQRITSGADAENAAGPGFAAVHGADAKEVYARDLTL 2128 Query 2086 DRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAE 2144 D+F+DA TL+TA LPGPSPE+RTVLLTGATGFLGRYLVLE L +L+ VDG+LICLVRA Sbjct 2129 DKFLDATTLSTAPTLPGPSPEVRTVLLTGATGFLGRYLVLEWLEQLEQVDGKLICLVRAR 2188 Query 2145 SDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDL 2204 SDE+A RLEKTF++GDPELLRHF+ELA + L+VVAGDK + +LGLD+ W++LA+TVDL Sbjct 2189 SDEEAWGRLEKTFNTGDPELLRHFQELAEEHLQVVAGDKGQANLGLDEQTWQQLADTVDL 2248 Query 2205 IVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTED 2263 IVDSAA+VN PY ELF PNV GTAELIR+ALTT+ KPF YVST+DVG IEPSAFTED Sbjct 2249 IVDSAAVVNGVLPYSELFTPNVGGTAELIRLALTTRKKPFAYVSTSDVGRQIEPSAFTED 2308 Query 2264 ADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQL 2323 ADIRVIS TR +DG +A GYG SKWAGEVLLREA+DLC LPV+VFR MILADTSYAGQL Sbjct 2309 ADIRVISATRVIDGSYANGYGNSKWAGEVLLREAHDLCGLPVSVFRSDMILADTSYAGQL 2368 Query 2324 NMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSS 2383 N++D TRM+LS++ATG AP+SFY D++GNRQR+HFD LPV FVAEAIA LGA+V Sbjct 2369 NVTDIFTRMILSIVATGTAPKSFYRLDADGNRQRSHFDALPVEFVAEAIAKLGAQV---- 2424 Query 2384 LAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRH 2443 + GF TYHVMNPHDDGIGLDEYVDWLIEAGYPI R+DDF EWLQRFE L LP+RQR++ Sbjct 2425 MDGFETYHVMNPHDDGIGLDEYVDWLIEAGYPIERVDDFGEWLQRFETGLRGLPERQRQN 2484 Query 2444 SVLPMLLAS--NSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIIN 2501 SVL MLL + + LQP +P RG APTDRFRAAV+ AKVGSD DIPH+SAP I+ Sbjct 2485 SVLQMLLLLLRDPKNLQPAEPARGAFAPTDRFRAAVQEAKVGSDN---DIPHISAPVIVK 2541 Query 2502 YVTNLQLLGLL 2512 YVT+LQLLGLL Sbjct 2542 YVTDLQLLGLL 2552 Score = 763 bits (1970), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/576 (69%), Positives = 449/576 (78%), Gaps = 11/576 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R + SID LDG E RLDEWGNRA+LT P P SIP M AAQVAR EA A+ SM Sbjct 7 RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAPASIPGMFAAQVARSAEAVALSFEGRSM 66 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TYRELDEASNRLAH LA GA PGECVALLF R A+V+++AVLKTGAAYLPIDPA P Sbjct 67 TYRELDEASNRLAHLLAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPA 126 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPP----PMPAAVNLA 1634 R+ FMLGDA P+AAVTTAGLR RL G DLP+IDV +A A T P P P+ ++A Sbjct 127 ARMEFMLGDATPIAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIA 186 Query 1635 YILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA--QVWSQCHSYGFDASAWEIWGAL 1692 Y++YTSGTTG PKGV +THRNVT +L +L + QVWSQ HS FD S WE WGAL Sbjct 187 YMIYTSGTTGTPKGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGAL 246 Query 1693 LGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACP 1752 L GGRLV+VPESVA SP+D H LLVAE V+VL+QTP+AV ML +GL+S ALVVAGEACP Sbjct 247 LHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACP 306 Query 1753 AALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 A +VDRWAPGRVM+NAYGPTE T+ AA+SAPL SG PPIG PV GAALFVLD WLRP Sbjct 307 AEVVDRWAPGRVMINAYGPTEATVYAAMSAPLTAESGAPPIGSPVPGAALFVLDKWLRPA 366 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELYIAG GV GY RRAGLTASRFVACPFGG GARMYRTGDLV W ADGQL++L Sbjct 367 PEGVVGELYIAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWGADGQLQYL 426 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLVGY T G DP Sbjct 427 GRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYIT----GTADP 482 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEK 1991 A LR QL +RLP Y+VPAAVVV+++LPLTVNGKLD RALPAPEY G YRAP+ E+ Sbjct 483 AELRTQLGKRLPAYMVPAAVVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRAPSNHTEE 542 Query 1992 TVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +A I+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 543 ILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 578 Score = 108 bits (270), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 180/734 (25%), Positives = 284/734 (39%), Gaps = 74/734 (10%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L ++GAAPG+ + +D+ I ++A G Y D A + + GD Sbjct 82 LAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPAARMEFML---GDATP 138 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLAT-------KTAYIMPTSGTTGQP 587 + V A + + G D VDE ++ + AY++ TSGTTG P Sbjct 139 IAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIAYMIYTSGTTGTP 198 Query 588 KLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAM 647 K V ++H ++ F + G Q L D+SV E +G G RLV Sbjct 199 KGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGALLHGGRLVVVPES 258 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 G L D LVA T++ + +L +G +D+ +V+ GEA V Sbjct 259 VAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEG--LDSTA------LVVAGEACPAEVV 310 Query 708 DKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL--- 764 D+W + G ++++YGPTEATV A + T + +G P+ +F+ Sbjct 311 DRW-----APGRVMINAYGPTEATVYAA----MSAPLTAESGAPPIGSPVPGAALFVLDK 361 Query 765 --------AFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE 813 GE+ I G VA GY G+ F G R + TGD V A+ Sbjct 362 WLRPAPEGVVGELYIAGRGVATGYARRAGLTASRF-VACPFGGPGARMYRTGDLVRWGAD 420 Query 814 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRT 869 G + GR D VKI G R+++ E+ +A V AV G V + + Sbjct 421 GQLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTA 480 Query 870 REGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTA 929 E R+ +V VV + ++P NGK+D LP AG A Sbjct 481 DPAELRTQLGKRLPAYMVPAA-----VVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRA 535 Query 930 ETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIG 988 + L+ I+++ LG +G D S G S+ ++++ R G D+ Sbjct 536 PSNHTEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGVICRPRDVFV 594 Query 989 ADTAANLADYAPTPDAPTGEDRFRPLVAAQRPA-AIPLSFAQRRLWFLDQLQRPAPVYNM 1047 T A LA A G D + + P A P+ + +L +Q P +N Sbjct 595 EQTVARLARV-----ASDGADEEQVVDEGIGPVQATPI------MRWLQTVQGPIDDFNQ 643 Query 1048 AVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDAT 1107 + L + + + + ++ RH LR L + D + + Sbjct 644 TMVLAAPSGVTADDVAVVLQALLDRHPMLRLRVEDDGAGGWNLQAPEPGSVRAADCLQSV 703 Query 1108 AWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAVAHHIAADGWSVAPLT 1166 D L A+ AAR + + + W A + L + HH+A DG S L Sbjct 704 ----DTLSDAVLVAARSRLNPGAGVMVSAVW----ASETSQLALIIHHVAVDGVSWRTLI 755 Query 1167 ADLSAAYASRCAGR 1180 DL+ A+A +G+ Sbjct 756 EDLNIAWAQHHSGQ 769 Score = 96.7 bits (239), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 148/544 (28%), Positives = 218/544 (41%), Gaps = 49/544 (9%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L++ GA PG+ + + + I ++A G Y D A + R + GD Sbjct 1577 LIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALP-AARIEFLL--GDAEP 1633 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALL----ATKTAYIMPTSGTTGQPKLV 590 V VV AA + + G VD+ A L + AY++ TSGTTG PK V Sbjct 1634 VAVVTTAALRSRLDGCKPSVVDVDDPALDGQPSAALPVPSSDNIAYLIYTSGTTGVPKGV 1693 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTG 650 +SH ++A +++ G Q L D+SV EI+G G RLV Sbjct 1694 AVSHDNVAQLVESLHADLPEGG--VWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAA 1751 Query 651 DLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKW 710 L D LVA T++ + +L +G +D+ +V+ GEA VD+W Sbjct 1752 SPDELHDLLVAEGVTVLSQTPSAVGMLSPEG--LDSTA------LVVAGEACPVEIVDRW 1803 Query 711 LESAASQGISLLSSYGPTEATVVATFLPIVCDQT--------TMDGALL---RLGRPILP 759 + G ++++YGPTEATV A + T AL R RP P Sbjct 1804 -----APGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPP 1858 Query 760 NTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFP 816 V GE+ I G VA GY G+ F G R + TGD V + +G Sbjct 1859 GVV----GELYIAGHGVATGYARRSGLTASRF-VACPFGGPGARMYRTGDLVRWNQDGQL 1913 Query 817 VFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDA 876 + GR D VK+ G R+++ EV +A V AV G +R Sbjct 1914 EYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPG----DKRLVGYITGT 1969 Query 877 AAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ 933 A IR+ L + VV + +P NGK+D LP G A T Sbjct 1970 ADPVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNP 2029 Query 934 RAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTA 992 ++ I++R LG + D S G SL +R++ E + LS+ L + + Sbjct 2030 TEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIAEINTAVDGALSVRTLFDSQSV 2089 Query 993 ANLA 996 L+ Sbjct 2090 RALS 2093 >gi|254819610|ref|ZP_05224611.1| linear gramicidin synthetase subunit B [Mycobacterium intracellulare ATCC 13950] Length=2552 Score = 1507 bits (3901), Expect = 0.0, Method: Compositional matrix adjust. Identities = 864/1515 (58%), Positives = 1031/1515 (69%), Gaps = 79/1515 (5%) Query 1023 IPLSFAQRRLWFLDQL-QRPAP-VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F Q P VY + + + + G LD+ L AV VV RH +L F Sbjct 1092 LPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGALDSHRLHEAVHTVVNRHPNLAARF 1151 Query 1081 PAVDGVPRQL-----VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+ V+ R LG + D P R++ DLA R Sbjct 1152 CPQFGEPVQVIPADPVMAWRYIQLGPEDPD----PEQRVEELCAAERAAVSDLANRPAFR 1207 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R AD+ + V HHI DGWS+ L ++ A Y D P P Y Y Sbjct 1208 AALIRTADNRYRFVLTNHHIVMDGWSLPILLREILANYYG-------DQLPAPATYRSYL 1260 Query 1196 LWQREILGDLDDSDSPIAAQLAYWE-------NALAGMPERLRLPTARPYPPVADQRGAS 1248 W L D + AAQ A+ E L G R+RL R A Sbjct 1261 TW----LAGQDRA----AAQAAWREVLDGFDAPTLVGPAGRMRL-----------GRRAV 1301 Query 1249 LVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA- 1306 A + + +AR + T V+ AG A LL +L+G DVA G ++GR +D A Sbjct 1302 ESYRLSAETTRALGELARSCHTTVNTVLQAGWAQLLMRLTGHHDVAFGTAVSGRPADLAG 1361 Query 1307 LDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT 1366 +++VG +NT+ +R N+ + + A++L Q++ E++ + + R Sbjct 1362 AESMVGLLINTVPVRANIDAETTVADVLDQLQQHHNDTLEHEHLALSEI------HRVTG 1415 Query 1367 HHPLIQVMLAWQDNPVG-QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGG 1425 H L + +++ P+ + LG + + I T R + L+ G E +G Sbjct 1416 HDALFDTLFLYENYPIDTSVPLGFHE---LAITDVTNREYNHYPLSVMALPGRE---LGL 1469 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 VEY TDVF+A I+ + ER ++VL + P R + ++D +D E LD WGNR+VL+ Sbjct 1470 RVEYDTDVFDAAGIEKMTERFQRVLSEMTVDPTRRLMALDVVDEAEHELLDSWGNRSVLS 1529 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 PA T SIP + AAQVAR P+A A+ SMTYRELDEA+NRLAH L GAGPGE V Sbjct 1530 QPA-TGTSIPGLFAAQVARTPDAAALSFDGRSMTYRELDEAANRLAHLLIEEGAGPGERV 1588 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+V+++AVLKTGAAYLPIDPA P R+ F+LGDA PVA VTT GLRSRL G Sbjct 1589 ALLFSRSADAIVSILAVLKTGAAYLPIDPALPTARIEFLLGDAEPVAVVTTTGLRSRLEG 1648 Query 1606 HDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLP 1664 +IDV D AL A P P P+P++ N+AY++YTSGTTG PKGV +TH NVT+L SL Sbjct 1649 CRPTVIDVDDPALDAQPSDPLPIPSSDNIAYLIYTSGTTGVPKGVAVTHDNVTQLVESLH 1708 Query 1665 ARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL 1724 A L A VW+Q HS FD S EIWGALL GGRLV+VPESVAASP++ H LLV+E V+VL Sbjct 1709 ADLPEAGVWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHALLVSEGVTVL 1768 Query 1725 TQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL 1784 +QTP+AV ML +GL+S ALVVAGEACP +VDRWAPGRVM+NAYGPTE T+ AA+SAPL Sbjct 1769 SQTPSAVGMLSPEGLDSTALVVAGEACPVEVVDRWAPGRVMINAYGPTEATVYAAMSAPL 1828 Query 1785 RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVA 1844 + G+ PIG PV AALFVLD WLRP P GV GELYIAG GV GY RR+GLTASRFVA Sbjct 1829 QAGAASAPIGSPVPRAALFVLDRWLRPAPEGVVGELYIAGHGVATGYSRRSGLTASRFVA 1888 Query 1845 CPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQA 1904 CPFGG GARMYRTGDLV W DGQLE+LGR D+QVKIRGYRIELGEV ALA L GV QA Sbjct 1889 CPFGGPGARMYRTGDLVRWSHDGQLEYLGRADEQVKIRGYRIELGEVQAALAGLDGVEQA 1948 Query 1905 VVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNG 1964 VIAREDRPGDKRLVGY T G DP G+R QLA RLP Y+VPAAVVV+DALPLTVNG Sbjct 1949 AVIAREDRPGDKRLVGYIT----GTADPVGIRIQLADRLPAYMVPAAVVVLDALPLTVNG 2004 Query 1965 KLDHRALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAM 2023 KLD RALPAPEY G Y AP+ P E+T+AGIFARVLG+ERV VDDSFFELGGDSL+AM Sbjct 2005 KLDKRALPAPEYQKRGGEYVAPSNPTEETIAGIFARVLGMERVSVDDSFFELGGDSLSAM 2064 Query 2024 RVIAAINTTLNADLPVRALLHASSTRGLSQLL--GRDARPTSDPRLVSVHGDNPTEVHAS 2081 RVIA INT L+ L VR L + S R LSQ + G D + P +VHG + TEV+A Sbjct 2065 RVIAEINTALDGALSVRTLFDSQSIRALSQRIASGADTENAAGPGFAAVHGADATEVYAR 2124 Query 2082 DLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICL 2140 DLTLD+FIDA TLAT +L PS E+RTVLLTGATGFLGRYLVLE L +L+ V+G+LICL Sbjct 2125 DLTLDKFIDATTLATVPSLRAPSSEVRTVLLTGATGFLGRYLVLEWLEQLEQVEGKLICL 2184 Query 2141 VRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAE 2200 VRA SDEDA RRLEKTFDSGDPELLRHF+ELA D L+VVAGDK + +LGLD WR+LA+ Sbjct 2185 VRARSDEDAWRRLEKTFDSGDPELLRHFRELAEDHLQVVAGDKGQANLGLDDQTWRQLAD 2244 Query 2201 TVDLIVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSA 2259 TVDLIVDSAA+VN PY+ELF PNV GTAELIR+ALTTK+KP+ YVST+DVG IEPSA Sbjct 2245 TVDLIVDSAAVVNGVLPYNELFTPNVGGTAELIRLALTTKMKPYAYVSTSDVGRQIEPSA 2304 Query 2260 FTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSY 2319 FTEDADIRVIS TR VDG +A GYG SKWAGEVLLREA+DLC LPV+VFR MILADTSY Sbjct 2305 FTEDADIRVISATRVVDGSYANGYGNSKWAGEVLLREAHDLCGLPVSVFRSDMILADTSY 2364 Query 2320 AGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARV 2379 AGQLN++D TRM+LS++ATG AP+SFY+ D+EGNRQ AHFDGLPV FVAEAIA LGA+V Sbjct 2365 AGQLNVADIFTRMILSVVATGCAPKSFYQLDAEGNRQSAHFDGLPVEFVAEAIAKLGAQV 2424 Query 2380 AGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDR 2439 + GF TYHVMNPHDDGIGLDEYVDWLIEAGYPI R+ DF EWLQRFE L LP+R Sbjct 2425 ----MEGFETYHVMNPHDDGIGLDEYVDWLIEAGYPIERVGDFGEWLQRFETGLRGLPER 2480 Query 2440 QRRHSVLPMLLAS--NSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAP 2497 QR++SVL MLL + + LQP +P RG APTDRFRAAV+ AKVG D DIPHVSAP Sbjct 2481 QRQNSVLQMLLLLLRDPKNLQPAEPARGAFAPTDRFRAAVQEAKVGPDN---DIPHVSAP 2537 Query 2498 TIINYVTNLQLLGLL 2512 I+ YVT+LQLLGLL Sbjct 2538 VIVKYVTDLQLLGLL 2552 Score = 771 bits (1992), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/573 (70%), Positives = 454/573 (80%), Gaps = 8/573 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R + SID LDG E RLDEWGNRA+LT P P SIP+M AAQVAR P+A A+ SM Sbjct 7 RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAPTSIPEMFAAQVARAPQAAALSFEGRSM 66 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TY ELDEA+NRLAH LA GA PGECVALLF R A A+++++AVLKTGAAYLPIDPA P Sbjct 67 TYLELDEAANRLAHLLAEQGAAPGECVALLFSRSAEAIISILAVLKTGAAYLPIDPALPA 126 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA-AYPGTPPPMPAAVNLAYIL 1637 R+ FMLGDA P+AAVTTA LR+RL G DLP+IDV +A A + P + P PA ++AY++ Sbjct 127 ARMEFMLGDATPIAAVTTASLRTRLDGFDLPVIDVDEAAADSQPSSALPGPAPDDIAYMI 186 Query 1638 YTSGTTGEPKGVGITHRNVTRLFASLPARL--SAAQVWSQCHSYGFDASAWEIWGALLGG 1695 YTSGTTG PKGV +THRNVT +L A+L A QVWSQ HS FD S WEIWGALL G Sbjct 187 YTSGTTGVPKGVAVTHRNVTEFLKTLHAKLPSGAGQVWSQWHSLVFDVSVWEIWGALLHG 246 Query 1696 GRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAAL 1755 GRLV+VPESVA SP+D H LLVAE V+VL+QTP+AV ML +GLES ALVVAGEACPA + Sbjct 247 GRLVVVPESVAGSPDDLHDLLVAEKVNVLSQTPSAVGMLSPEGLESTALVVAGEACPAEV 306 Query 1756 VDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAG 1815 VDRWAPGRVM+NAYGPTE T+ AA+SAPL SG PPIG PV GAALFVLD WLRP P G Sbjct 307 VDRWAPGRVMINAYGPTEATVYAAMSAPLTGDSGAPPIGSPVPGAALFVLDKWLRPAPEG 366 Query 1816 VAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRT 1875 V GELY+AG GV GY RR+GLTASRFVACPFGG GARMYRTGDLV W DGQL++LGR Sbjct 367 VVGELYVAGRGVATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWGTDGQLQYLGRA 426 Query 1876 DDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGL 1935 D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLVGY T G DPA L Sbjct 427 DEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYIT----GTADPAEL 482 Query 1936 RAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEKTVA 1994 R QL +RLP Y+VPAAVVV++ALPLTVNGKLD RALPAPEY G YRAP+ E+ +A Sbjct 483 RTQLGKRLPAYMVPAAVVVLEALPLTVNGKLDKRALPAPEYHKRAGEYRAPSNHTEEILA 542 Query 1995 GIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 GI+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 543 GIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 575 Score = 103 bits (257), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 136/523 (27%), Positives = 208/523 (40%), Gaps = 49/523 (9%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L ++GAAPG+ + + + I ++A G Y D A + + GD Sbjct 82 LAEQGAAPGECVALLFSRSAEAIISILAVLKTGAAYLPIDPALPAARMEFML---GDATP 138 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLA----TKTAYIMPTSGTTGQPKLV 590 + V A+ + + G D VDE + L AY++ TSGTTG PK V Sbjct 139 IAAVTTASLRTRLDGFDLPVIDVDEAAADSQPSSALPGPAPDDIAYMIYTSGTTGVPKGV 198 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTG 650 ++H ++ F + GA Q L D+SV EI+G G RLV G Sbjct 199 AVTHRNVTEFLKTLHAKLPSGAGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVAG 258 Query 651 DLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKW 710 L D LVA + ++ + +L +G A +V+ GEA VD+W Sbjct 259 SPDDLHDLLVAEKVNVLSQTPSAVGMLSPEGLESTA--------LVVAGEACPAEVVDRW 310 Query 711 LESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL------ 764 + G ++++YGPTEATV A + T D +G P+ +F+ Sbjct 311 -----APGRVMINAYGPTEATVYAA----MSAPLTGDSGAPPIGSPVPGAALFVLDKWLR 361 Query 765 -----AFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFP 816 GE+ + G VA GY G+ F G R + TGD V +G Sbjct 362 PAPEGVVGELYVAGRGVATGYARRSGLTASRF-VACPFGGPGARMYRTGDLVRWGTDGQL 420 Query 817 VFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRTREG 872 + GR D VKI G R+++ E+ +A V AV G V + + Sbjct 421 QYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTADPA 480 Query 873 EQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETG 932 E R+ +V VV + +P NGK+D LP AG A + Sbjct 481 ELRTQLGKRLPAYMVPAA-----VVVLEALPLTVNGKLDKRALPAPEYHKRAGEYRAPSN 535 Query 933 QRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 L+ I+++ LG +G D S G S+ ++++ R Sbjct 536 HTEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARAR 578 Score = 90.5 bits (223), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 142/555 (26%), Positives = 214/555 (39%), Gaps = 81/555 (14%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEIS-------------- 520 L++ GA PG+ + + I ++A G Y D A + Sbjct 1577 LIEEGAGPGERVALLFSRSADAIVSILAVLKTGAAYLPIDPALPTARIEFLLGDAEPVAV 1636 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 V T + +G TV+DV L D L + + AY++ T Sbjct 1637 VTTTGLRSRLEGCRPTVIDVDDPALDAQPSDPLPIPSSDNI-------------AYLIYT 1683 Query 581 SGTTGQPKLVRISHGSLAVFCDAIS----RAYGWGAHDTVLQCAPLTSDISVEEIFGGAA 636 SGTTG PK V ++H ++ +++ A W Q L D+SV EI+G Sbjct 1684 SGTTGVPKGVAVTHDNVTQLVESLHADLPEAGVWA------QWHSLVFDVSVHEIWGALL 1737 Query 637 CGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLR 693 G RLV S A +L AL LV+ T++ + +L +G +D+ Sbjct 1738 HGGRLVVVPESVAASPDELHAL---LVSEGVTVLSQTPSAVGMLSPEG--LDSTA----- 1787 Query 694 QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRL 753 +V+ GEA VD+W + G ++++YGPTEATV A + A + Sbjct 1788 -LVVAGEACPVEVVDRW-----APGRVMINAYGPTEATVYAA----MSAPLQAGAASAPI 1837 Query 754 GRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGSRRR 800 G P+ +F+ GE+ I G VA GY G A G R Sbjct 1838 GSPVPRAALFVLDRWLRPAPEGVVGELYIAGHGVATGYSRRSGLTASRFVACPFGGPGAR 1897 Query 801 AFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSL 860 + TGD V +G + GR D VKI G R+++ EV +A V AV Sbjct 1898 MYRTGDLVRWSHDGQLEYLGRADEQVKIRGYRIELGEVQAALAGLDGVEQAAVIAREDRP 1957 Query 861 GVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKIDSDNLPR 917 G +R A IR+ L + VV + +P NGK+D LP Sbjct 1958 G----DKRLVGYITGTADPVGIRIQLADRLPAYMVPAAVVVLDALPLTVNGKLDKRALPA 2013 Query 918 LPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRY 976 G A + ++ I++R LG + D S G SL +R++ E Sbjct 2014 PEYQKRGGEYVAPSNPTEETIAGIFARVLGMERVSVDDSFFELGGDSLSAMRVIAEINTA 2073 Query 977 LGWRLSLLDLIGADT 991 L LS+ L + + Sbjct 2074 LDGALSVRTLFDSQS 2088 >gi|296164632|ref|ZP_06847199.1| linear gramicidin synthetase subunit D [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900051|gb|EFG79490.1| linear gramicidin synthetase subunit D [Mycobacterium parascrofulaceum ATCC BAA-614] Length=7454 Score = 1506 bits (3899), Expect = 0.0, Method: Compositional matrix adjust. Identities = 868/1594 (55%), Positives = 1061/1594 (67%), Gaps = 89/1594 (5%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEIS 520 L++RGA PG + + + I ++A G Y + DTA + Sbjct 4126 LIERGAGPGASVAVVLSRSTEAIVAILAVLKTGAAYLPIDPALPAARIEFMLSDTAPVAA 4185 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 + T A+ E G ++ V+DV + LA G V H I+ T Sbjct 4186 LTTAALAEKLAGYVLPVIDVHSPALA--GQPATAPAPGPEPEDVAH----------IIYT 4233 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V +SH ++ DA G+ Q D SV EI+G G R Sbjct 4234 SGTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWTQFHSYAFDFSVWEIWGALLHGGR 4293 Query 641 LV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVI 697 LV + A D AL LV T++ A ++L G A+ VI Sbjct 4294 LVVVPEAVARSPKDFHAL---LVTERVTVLSQTPAAVRMLSPQGLEGTAL--------VI 4342 Query 698 GGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVAT-FLPIVCDQ------TTMDGAL 750 G E + VD+W + G +++ YGPTE T+ AT P+ + + G Sbjct 4343 GAEPVPAEVVDRW-----APGRVMVNVYGPTETTIFATASTPLAAKGGAPPTGSAVPGTA 4397 Query 751 LRLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF-GTVTAADGSRRRAFATGD 806 L + L T GE+ + G V GY+ G+ G F A G+R + TGD Sbjct 4398 LFVLDGWLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGARM--YRTGD 4455 Query 807 RVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKS 866 V A+G + GR DA VKI G R++I E+ +A V V + G Sbjct 4456 LVCWGADGQLRYVGRADAQVKIRGYRIEIGEIQSTLAALDGVEQAVVVVREDRPG----- 4510 Query 867 QRTREGEQDAAAATRIRLVLVSLGVSSFFV----VGVPNIPRKPNGKIDSDNLPRLPQWS 922 + G +A ++ + + V V +P +P NGK+D+ LP P++ Sbjct 4511 DKRLVGYLTGSAEPAALRAALAERLPGYMVPAAIVALPELPMTVNGKLDTRALPA-PEYH 4569 Query 923 AAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRL 981 G T L+ I+++ LG +G D S G S+ +R++ L L Sbjct 4570 GTGYRAPSTPTEEI-LAGIYAQVLGVDRVGIDQSFFDLGGDSISAMRLIAAVNTDLDEYL 4628 Query 982 SLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRP 1041 S+ L A T A LA P G R PLVA RPA +PLSFAQ RLWFLDQLQ P Sbjct 4629 SVRALFEAPTIAQLA-----PRIGEGTGRLEPLVAGPRPAVVPLSFAQSRLWFLDQLQGP 4683 Query 1042 APVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGC 1101 +PVYNMA A+RLRG LD +ALGAA+ADVV RHESLRTVF A DG P+Q+V+ A +AD G Sbjct 4684 SPVYNMAAAMRLRGRLDAQALGAALADVVARHESLRTVFAAPDGTPQQVVVPAEQADFGW 4743 Query 1102 DIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWS 1161 ++DA WPA RL A++ AAR +FDL+T+IPLR WLFR+ADDEHVLVAV HHIAADGWS Sbjct 4744 RVIDAGGWPASRLDDAVKAAARDTFDLSTDIPLRAWLFRVADDEHVLVAVVHHIAADGWS 4803 Query 1162 VAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWEN 1221 + PL ADL AYASRCAG++P+WA LPVQYVDYTLWQR+ GDL DSDS IAAQLAYWE+ Sbjct 4804 LRPLAADLGVAYASRCAGQSPEWAELPVQYVDYTLWQRDQFGDLKDSDSRIAAQLAYWED 4863 Query 1222 ALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLA 1281 ALAGMPERL+LPT RPYP VADQRGAS+ +DWPA +QQQV +AR+HNATSFMVV A LA Sbjct 4864 ALAGMPERLQLPTDRPYPQVADQRGASVPIDWPADLQQQVAAVAREHNATSFMVVQAALA 4923 Query 1282 VLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARS 1341 VLLSK+ + DVAVGFPIAGR DPALD+LVGFFVNTLVLRV++AGDP+FAELL +VR RS Sbjct 4924 VLLSKVGATSDVAVGFPIAGRRDPALDDLVGFFVNTLVLRVDVAGDPTFAELLDRVRTRS 4983 Query 1342 LAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLN-------LGDLQATP 1394 L A+E+QDVPFEVLV+R+ PTR+LTHHPLIQVMLAWQ N GQ N LGD++ + Sbjct 4984 LEAFEHQDVPFEVLVERVNPTRSLTHHPLIQVMLAWQ-NFGGQDNDAATGLALGDVRVSS 5042 Query 1395 MPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVA 1454 +P+DT+ ARMDL FSLAER++EG+EP GIGG VE+RTDVF+A++I+ L+ERL++VL A+ Sbjct 5043 IPLDTQVARMDLTFSLAERWTEGNEPGGIGGRVEFRTDVFDAESIETLVERLQRVLAAMT 5102 Query 1455 AAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCG 1514 P RTVSS+D LD ERARL+E G+RA LTAPA P+SIP AAQVAR P+A A+ CG Sbjct 5103 TDPARTVSSVDLLDAAERARLEELGHRAALTAPAAEPLSIPAAFAAQVARTPDAPALGCG 5162 Query 1515 DASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDP 1574 + TYRELDEA+NRLAH LAG GAGPG VALLF R A A+VA++A LKTGAAYLP+DP Sbjct 5163 ARTWTYRELDEAANRLAHLLAGRGAGPGHTVALLFNRSAEAIVAILAALKTGAAYLPVDP 5222 Query 1575 ANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNL 1633 A+P R+ FML DA PVAA+TTA L RL HD+ +IDV D A+ P T P P+A ++ Sbjct 5223 AHPAARIGFMLADAAPVAALTTADLADRLDEHDVAVIDVDDPAVETQPATALPAPSAEDV 5282 Query 1634 AYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALL 1693 AY++YTSGTTG PKGV ++HR+VT L AS+ ARL A VWSQ HSYGFD S WEI+GALL Sbjct 5283 AYLIYTSGTTGVPKGVAVSHRSVTGLMASVDARLPDAGVWSQWHSYGFDVSVWEIFGALL 5342 Query 1694 GGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPA 1753 GGRLV+VP++V SP D H LLV E VSVL+QTP+A AML GLES ALVVAGEACP Sbjct 5343 RGGRLVVVPDAVVRSPEDLHALLVGEGVSVLSQTPSAAAMLDPAGLESAALVVAGEACPT 5402 Query 1754 ALVDRWA-PGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 LVDRWA GRVM+NAYGPTE T+ AAISAPL PGSG+ PIG PV+GAALFVLD +LRPV Sbjct 5403 DLVDRWATSGRVMINAYGPTEATVYAAISAPLTPGSGVVPIGSPVAGAALFVLDEYLRPV 5462 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELY+AG G+ GYWRRA LTASRFVACPFGG G RMYRTGDLVCW ADGQL++L Sbjct 5463 PPGVVGELYVAGGGLARGYWRRAALTASRFVACPFGGPGDRMYRTGDLVCWGADGQLQYL 5522 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVKIRGYRIELGE+ ALAEL GV QA V+AREDRPGDKRLVGY T G DP Sbjct 5523 GRADEQVKIRGYRIELGEIQAALAELRGVRQAAVVAREDRPGDKRLVGYIT----GKADP 5578 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKT 1992 A LRA+LA RLP Y+VP AVV +DALPLT NGKLD RALPAPEY D + YRAP PVE+ Sbjct 5579 AELRARLADRLPAYMVPVAVVTLDALPLTPNGKLDARALPAPEYSDADRYRAPGTPVEEI 5638 Query 1993 VAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 +AGI+A+VLG+ER+GVDDSFF+LGGDS+++M+V+ Sbjct 5639 LAGIYAQVLGVERIGVDDSFFDLGGDSISSMQVV 5672 Score = 1410 bits (3650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 843/1557 (55%), Positives = 1024/1557 (66%), Gaps = 94/1557 (6%) Query 506 AGCGYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVT 565 A G+ + D +++ T A+ DG V V+DV D+ + + Sbjct 1628 ARIGFVLGDAEPVVALSTAALAGRLDGHAVVVIDV----------DDAGIDAEPDIGLPE 1677 Query 566 HDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAY---GWGAHDTVLQCAPL 622 DA AY++ TSGTTG PK V ++H ++ A+ G +H L Sbjct 1678 PDA---EGLAYVIYTSGTTGVPKGVGVTHRNVTALLGALGAGLPVPGVWSH-----AHSL 1729 Query 623 TSDISVEEIFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCA 679 D+SV EIF G RLV A +L A++ + R + + P+A+ L Sbjct 1730 AFDVSVWEIFAPLLRGGRLVIVDEDTARAPEELRAVL--IGERVSVLTQTPSAIAML--- 1784 Query 680 DGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF--- 736 D +D + +V+ GEA VD+W + G L+++YGPTE T+ Sbjct 1785 DPGGLDEVA------VVLAGEACPAEVVDRW-----APGRVLVNAYGPTETTMCVAISAP 1833 Query 737 ------LPIVCDQTTMDGALLRLG--RPILPNTVFLAFGEVVIVGDLVADGYLGIDG-DG 787 +P + G L+ G RP+ P V GE+ + G VA GYLG G G Sbjct 1834 LGPGSGVPPIGSPVPGAGLLVLDGWLRPVPPGVV----GELYVAGAGVAAGYLGRAGLTG 1889 Query 788 FGTVTAADGSR-RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDP 846 V G+ R + TGD A+G + GR D VKI G R+++ E+ ++ Sbjct 1890 SRFVACPFGAAGLRMYRTGDLACWGADGQLRYLGRADEQVKIRGYRIELGEIQAALSALA 1949 Query 847 AVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFV----VGVPNI 902 V V G + G A + +S + F V VG+ + Sbjct 1950 GVEQAVVIAREDRPG-----DKRLVGYVTGGADVEVLRAQLSARLPGFMVPTAIVGLDRV 2004 Query 903 PRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGI 961 P NGK+D LP P +S+ + +T L+ I++ LG + D S G Sbjct 2005 PLTANGKLDIRALPA-PDYSSGDYHAPQTPTEEI-LAAIFADVLGLDRVSTDDSFFELGG 2062 Query 962 GSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPA 1021 S+ + ++ L L + + A T A LA G PLVAA RPA Sbjct 2063 ESISAMGLIAAVNTNLNAGLQVRVVFEAPTVAQLALRIGE-----GGGGLEPLVAADRPA 2117 Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 +PLSFAQ RLWFLDQLQ P+PVYNMA ALRLRG LD +ALGAA+ADVV RHESLRT+ Sbjct 2118 VVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLRGRLDADALGAALADVVARHESLRTLIA 2177 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRI 1141 A +G P+QLV +AD G +IVDATAW A +L AI +AAR++FDLA EIPLR LFR+ Sbjct 2178 APEGTPQQLVTPVEQADFGWEIVDATAWSAGQLDEAIGDAARYTFDLAAEIPLRAELFRV 2237 Query 1142 ADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREI 1201 +DEHVLVAV HHIAADG S+ PL DL AYASRCAG+AP WAPL VQYVDYTLWQR Sbjct 2238 DEDEHVLVAVVHHIAADGMSITPLVRDLGMAYASRCAGQAPGWAPLEVQYVDYTLWQRAQ 2297 Query 1202 LGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQV 1261 GDLDD +SPIAAQLAYWE ALAGMP+R++LP RPYP VADQRGA++ + WPA +QQ+V Sbjct 2298 FGDLDDRESPIAAQLAYWEEALAGMPDRVQLPADRPYPLVADQRGATVEIAWPAELQQRV 2357 Query 1262 RRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLR 1321 +AR+HNATSFMVV + LAVLLSK+S S DVAVGFPIAGR DPALD LVGFFVNTLVLR Sbjct 2358 GALARKHNATSFMVVQSALAVLLSKISASSDVAVGFPIAGRRDPALDELVGFFVNTLVLR 2417 Query 1322 VNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD-- 1379 V++ GDP+F +LL QVR RSLAAYENQDVPFEVLV+RL P R+LTHHPL+QVMLAWQ+ Sbjct 2418 VDVTGDPTFTDLLAQVRQRSLAAYENQDVPFEVLVERLNPARSLTHHPLVQVMLAWQNFA 2477 Query 1380 ----NPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFE 1435 PV L+LGD++ P+P+DT+TARMDL FSLAER+SE EPAGIGG VE+RTDVF+ Sbjct 2478 GQDAGPVAGLSLGDVEIAPIPVDTQTARMDLTFSLAERWSEAGEPAGIGGTVEFRTDVFD 2537 Query 1436 AQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIP 1495 A +I L+ RL++VL A+ P R +SS+D LD E A LD GNRAVLTAPA PVSIP Sbjct 2538 ADSIAALVARLQRVLTAMTVDPARPLSSLDLLDEAEHAHLDRIGNRAVLTAPAAAPVSIP 2597 Query 1496 QMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPA 1555 + AAQVAR PEA A+ C SMTYRELDEA+NRLA LAG GAGPGE VALLF R A A Sbjct 2598 ALFAAQVARTPEAVALACAGRSMTYRELDEAANRLAGVLAGRGAGPGESVALLFSRSAEA 2657 Query 1556 VVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD 1615 +VA++AVLK+GAAYLPIDPA P R+ F+L DA P+A VTTA L RL GHD+P+IDV D Sbjct 2658 IVAILAVLKSGAAYLPIDPALPESRIGFVLSDAAPLAVVTTADLADRLIGHDVPVIDVGD 2717 Query 1616 ---ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQV 1672 A AA P P ++AY++YTSGTTG PKGV +THRN T+L A + A L A V Sbjct 2718 IDTARAAALTAPGPE----DIAYLIYTSGTTGVPKGVAVTHRNATQLLARMDAGLPRAGV 2773 Query 1673 WSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVA 1732 WSQ HS FD S EI+GALL GGRLV+VPE+VA SP D H LLVAE VSVL+QTP+A A Sbjct 2774 WSQWHSLAFDVSVHEIFGALLHGGRLVVVPETVARSPEDCHALLVAEGVSVLSQTPSAAA 2833 Query 1733 MLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRP---GSG 1789 MLP +GL+SVALVVAGEACPA LVDRW P R M+NAYGPTE T+ AA+S PL SG Sbjct 2834 MLPPEGLDSVALVVAGEACPAELVDRWGPDRAMINAYGPTEATVYAAVSEPLTAESVESG 2893 Query 1790 MPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGG 1849 + PIG PV G ALFVLD LRPVPAGV GELY+AGAGV GYWRRAGLTA+RFVACPFGG Sbjct 2894 VVPIGSPVPGNALFVLDGRLRPVPAGVVGELYVAGAGVACGYWRRAGLTAARFVACPFGG 2953 Query 1850 SGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAR 1909 +G RMYRTGDLV WRADGQL++LGR D+QVKIRGYRIELGEV ALA L GV QAVV+AR Sbjct 2954 AGTRMYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEVRAALAWLDGVEQAVVVAR 3013 Query 1910 EDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHR 1969 EDRPGDKRLV Y T G DPAG RA LA+RLP Y++P AVV +DALPLT NGKLD R Sbjct 3014 EDRPGDKRLVAYIT----GTADPAGARAALAERLPAYMIPTAVVTLDALPLTPNGKLDTR 3069 Query 1970 ALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 ALPAPEY D + YRAP VE+ +AGI+A+VLGL+RVGVDDSFF+LGGDS+++M+V+ Sbjct 3070 ALPAPEYSDADQYRAPDNAVEEILAGIYAQVLGLDRVGVDDSFFDLGGDSISSMQVV 3126 Score = 1379 bits (3568), Expect = 0.0, Method: Compositional matrix adjust. Identities = 821/1510 (55%), Positives = 996/1510 (66%), Gaps = 73/1510 (4%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 A+++ TSGTTG PK V ++ ++A D++ Q D SV EI+G Sbjct 629 AHVIYTSGTTGVPKGVAVTQHNVAQLFDSLRIGIELTPEQVWTQFHSYAFDFSVWEIWGA 688 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARE--TTIVDLPTAVWQLLCADGDAIDAIGR 689 G RLV S + + AL+ RE T + P+AV LL DG +DA Sbjct 689 LLHGGRLVVVPESVSRSPEEFHALL----VREGATVLTQTPSAV-GLLPTDG--LDATA- 740 Query 690 SRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGA 749 +VIG E VD+W + G +++ YGPTE T+ A C +D Sbjct 741 -----LVIGAEPCPPELVDRW-----APGRVMVNVYGPTETTMWA------CKSAPLDAG 784 Query 750 --LLRLGRPILPNTVFLAFGEVV--IVGDLVADGYLGIDGDGFGT--VTAADGSR----- 798 +G P+ F E + + +V + YL DG G G +A SR Sbjct 785 SGFPPIGSPVT-RAAFFVLDEWLRPVPAGVVGELYLAGDGVGVGYWRRSALTASRFMACP 843 Query 799 -----RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV 853 R + TGD V +G + GR D VKI G R+++ E+ ++ V V Sbjct 844 FGAPGTRMYRTGDLVCWGTDGQLRYLGRADEQVKIRGYRIELGEIQAALSAVDGVEQAVV 903 Query 854 ELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGK 909 G V + + G AA A R+ +V V V +P +P NGK Sbjct 904 VAREDRPGDKRLVGYVTGTADAGAARAAVAERLPAYMVPAAV-----VVLPALPMTVNGK 958 Query 910 IDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIR 968 +D+ LP P + A L+ I++ LG +G D S G SL +R Sbjct 959 LDTRALPA-PDYRDTANYRAPATATEEILAGIFADVLGVERVGADDSFFDLGGDSLSTMR 1017 Query 969 ILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFA 1028 ++ L L + + A T A LA P G R PLVA +RPA IPLSFA Sbjct 1018 LISAVNAALDTDLPVRVVFEAPTVAQLA-----PRIDEGAGRLAPLVAGERPAVIPLSFA 1072 Query 1029 QRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPR 1088 Q RLWF+ QLQ P+PVYNMA ALRL G LD +AL AA+ADVVGRHESLRT+FPA +G P Sbjct 1073 QNRLWFIQQLQGPSPVYNMAAALRLGGPLDADALRAALADVVGRHESLRTLFPAREGTPE 1132 Query 1089 QLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVL 1148 Q+V+ A RAD G D+VDAT PA L I E H+FDLA+EIPLR LF + + EH+L Sbjct 1133 QVVLAAERADFGWDVVDATGLPAGELDGVIAETTAHTFDLASEIPLRAKLFALDEREHLL 1192 Query 1149 VAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDS 1208 V V HHIAADG S+ PL ADLS AYA+R AGRAP WA LPVQYVDYTLWQR GDLDDS Sbjct 1193 VIVVHHIAADGLSLTPLAADLSVAYAARSAGRAPGWADLPVQYVDYTLWQRAQFGDLDDS 1252 Query 1209 DSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQH 1268 +SPIAAQLAYWE ALAGMPERL LPT RPYPPVADQRG+S+VVDWPA +QQQVRR+AR+H Sbjct 1253 ESPIAAQLAYWEEALAGMPERLELPTDRPYPPVADQRGSSVVVDWPAELQQQVRRVAREH 1312 Query 1269 NATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDP 1328 NAT+FMVV A LAVLLSK+ S DV+VGFPIAGR D ALD LVGFFVNTLVLRV+L G+P Sbjct 1313 NATTFMVVQAALAVLLSKVIASTDVSVGFPIAGRRDRALDQLVGFFVNTLVLRVDLGGNP 1372 Query 1329 SFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ-----DNPVG 1383 S AELLG+V+ARSL A+E+QDVPFE+LV+RL P R+LTHHPL+QVMLAWQ D+P Sbjct 1373 SLAELLGRVQARSLEAFEHQDVPFELLVERLNPVRSLTHHPLVQVMLAWQNFAGHDDPAA 1432 Query 1384 QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLI 1443 L LGDL+ + +P+DT++ARMDLVFSLAER++E E AGIGG VE+RTDVF+A ++ LI Sbjct 1433 GLALGDLEVSSVPVDTQSARMDLVFSLAERWTETGEAAGIGGRVEFRTDVFDADTVEALI 1492 Query 1444 ERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVA 1503 RLR+VL A+ A P + +SS+D LD ERARL+ +GN+AVLT P T VS+P + AA+VA Sbjct 1493 GRLRRVLAALTADPGQALSSVDLLDDGERARLEGFGNQAVLTDPPSTSVSVPSLFAARVA 1552 Query 1504 RIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVL 1563 P A A+ CG S+TYRELD ASNRLAH L G GPG+ VALLF R A AV AM+AVL Sbjct 1553 EAPGAVALTCGGLSVTYRELDVASNRLAHHLVSRGVGPGQTVALLFSRSAEAVAAMMAVL 1612 Query 1564 KTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDA-LAAYPG 1622 KTGAAYLPIDP++P R+ F+LGDA PV A++TA L RL GH + +IDV DA + A P Sbjct 1613 KTGAAYLPIDPSSPDARIGFVLGDAEPVVALSTAALAGRLDGHAVVVIDVDDAGIDAEPD 1672 Query 1623 TPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFD 1682 P P A LAY++YTSGTTG PKGVG+THRNVT L +L A L VWS HS FD Sbjct 1673 IGLPEPDAEGLAYVIYTSGTTGVPKGVGVTHRNVTALLGALGAGLPVPGVWSHAHSLAFD 1732 Query 1683 ASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESV 1742 S WEI+ LL GGRLVIV E A +P + +L+ E VSVLTQTP+A+AML GL+ V Sbjct 1733 VSVWEIFAPLLRGGRLVIVDEDTARAPEELRAVLIGERVSVLTQTPSAIAMLDPGGLDEV 1792 Query 1743 ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAAL 1802 A+V+AGEACPA +VDRWAPGRV++NAYGPTETT+C AISAPL PGSG+PPIG PV GA L Sbjct 1793 AVVLAGEACPAEVVDRWAPGRVLVNAYGPTETTMCVAISAPLGPGSGVPPIGSPVPGAGL 1852 Query 1803 FVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVC 1862 VLD WLRPVP GV GELY+AGAGV GY RAGLT SRFVACPFG +G RMYRTGDL C Sbjct 1853 LVLDGWLRPVPPGVVGELYVAGAGVAAGYLGRAGLTGSRFVACPFGAAGLRMYRTGDLAC 1912 Query 1863 WRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYA 1922 W ADGQL +LGR D+QVKIRGYRIELGE+ AL+ LAGV QAVVIAREDRPGDKRLVGY Sbjct 1913 WGADGQLRYLGRADEQVKIRGYRIELGEIQAALSALAGVEQAVVIAREDRPGDKRLVGYV 1972 Query 1923 TEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGY 1982 T G D LRAQL+ RLPG++VP A+V +D +PLT NGKLD RALPAP+Y + Y Sbjct 1973 T----GGADVEVLRAQLSARLPGFMVPTAIVGLDRVPLTANGKLDIRALPAPDY-SSGDY 2027 Query 1983 RAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRAL 2042 AP P E+ +A IFA VLGL+RV DDSFFELGG+S++AM +IAA+NT LNA L VR + Sbjct 2028 HAPQTPTEEILAAIFADVLGLDRVSTDDSFFELGGESISAMGLIAAVNTNLNAGLQVRVV 2087 Query 2043 LHASSTRGLS 2052 A + L+ Sbjct 2088 FEAPTVAQLA 2097 Score = 1321 bits (3420), Expect = 0.0, Method: Compositional matrix adjust. Identities = 692/1050 (66%), Positives = 807/1050 (77%), Gaps = 17/1050 (1%) Query 1015 VAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHE 1074 +AA+RPA IPLSFAQ RLWF+DQ Q P+PVYN+AVALRLRG +DT A GAA+ADVVGRHE Sbjct 1 MAAERPAVIPLSFAQNRLWFIDQFQGPSPVYNIAVALRLRGRVDTGAFGAALADVVGRHE 60 Query 1075 SLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 SLRTVF + DG+P+Q+V+ RA LG VDA W RL+ A++ AA H+FDLA EIP+ Sbjct 61 SLRTVFASADGIPQQVVLPPERARLGFGTVDARGWTEGRLREAMDAAAGHTFDLANEIPI 120 Query 1135 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDY 1194 LF DDEHVLVAV HHIAADGWS+APL DL AYASRCAGR PDWAPL VQYVD+ Sbjct 121 HAELFTTDDDEHVLVAVVHHIAADGWSIAPLARDLGVAYASRCAGREPDWAPLSVQYVDF 180 Query 1195 TLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP 1254 TLWQR G+L+DSDS IAAQL +WE LAGMPE L+LPT RPYPPVAD RGA L VDWP Sbjct 181 TLWQRAQFGELEDSDSRIAAQLDFWEETLAGMPELLQLPTDRPYPPVADHRGARLAVDWP 240 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFF 1314 +QQQ+RR+AR+HNATSFMV+ A A LL+K++ S DVAVGFPIAGR DPALD LVGFF Sbjct 241 TELQQQIRRVAREHNATSFMVIQAAFAALLAKITASDDVAVGFPIAGRRDPALDELVGFF 300 Query 1315 VNTLVLRVN---LAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 VNTLVLRV+ L GDP+FAELL QVR RSLAA+E+QDVPFE LVDRL PTR+LTHHPLI Sbjct 301 VNTLVLRVDLKELGGDPTFAELLAQVRRRSLAAFEHQDVPFEFLVDRLNPTRSLTHHPLI 360 Query 1372 QVMLAWQD------NPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGG 1425 QV+L W++ NP L LGD+QATPMP++T TARMDL FSLA+R++E AGIG Sbjct 361 QVLLGWENFPGYDTNPTATLALGDVQATPMPVETHTARMDLTFSLADRWTEAGRHAGIGV 420 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 EYRTDV++A + LIERL+++L AV + P R +S++D LD E ARL WGN VL Sbjct 421 TAEYRTDVYDADTVVSLIERLQRLLAAVTSDPARRLSTVDLLDAGEHARLQRWGNTGVLA 480 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 PA TPVS+P + AAQ AR P+A A+ C SMTYRELDEA+NRLAH + GA PGE V Sbjct 481 RPA-TPVSVPALFAAQAARTPDAVALVCDGRSMTYRELDEAANRLAHLMIRHGARPGERV 539 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+VA+VA LK+GAAYLPIDPA P R+ FML DA P+AAVTTA L RL G Sbjct 540 ALLFPRSAQAIVAIVAALKSGAAYLPIDPALPAARMEFMLTDAAPIAAVTTAALAGRLDG 599 Query 1606 HDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL- 1663 DL +ID D A+ PGT PP P +LA+++YTSGTTG PKGV +T NV +LF SL Sbjct 600 FDLAVIDADDPAVDDQPGTAPPGPGPDDLAHVIYTSGTTGVPKGVAVTQHNVAQLFDSLR 659 Query 1664 -PARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 L+ QVW+Q HSY FD S WEIWGALL GGRLV+VPESV+ SP +FH LLV E + Sbjct 660 IGIELTPEQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPESVSRSPEEFHALLVREGAT 719 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VLTQTP+AV +LPT GL++ ALV+ E CP LVDRWAPGRVM+N YGPTETT+ A SA Sbjct 720 VLTQTPSAVGLLPTDGLDATALVIGAEPCPPELVDRWAPGRVMVNVYGPTETTMWACKSA 779 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PL GSG PPIG PV+ AA FVLD WLRPVPAGV GELY+AG GVGVGYWRR+ LTASRF Sbjct 780 PLDAGSGFPPIGSPVTRAAFFVLDEWLRPVPAGVVGELYLAGDGVGVGYWRRSALTASRF 839 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 +ACPFG G RMYRTGDLVCW DGQL +LGR D+QVKIRGYRIELGE+ AL+ + GV Sbjct 840 MACPFGAPGTRMYRTGDLVCWGTDGQLRYLGRADEQVKIRGYRIELGEIQAALSAVDGVE 899 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QAVV+AREDRPGDKRLVGY T G D RA +A+RLP Y+VPAAVVV+ ALP+TV Sbjct 900 QAVVVAREDRPGDKRLVGYVT----GTADAGAARAAVAERLPAYMVPAAVVVLPALPMTV 955 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAP+Y DT YRAPA E+ +AGIFA VLG+ERVG DDSFF+LGGDSL+ Sbjct 956 NGKLDTRALPAPDYRDTANYRAPATATEEILAGIFADVLGVERVGADDSFFDLGGDSLST 1015 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLS 2052 MR+I+A+N L+ DLPVR + A + L+ Sbjct 1016 MRLISAVNAALDTDLPVRVVFEAPTVAQLA 1045 Score = 825 bits (2131), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/1067 (50%), Positives = 659/1067 (62%), Gaps = 65/1067 (6%) Query 1023 IPLSFAQRRLWFLDQLQR----PAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRT 1078 +PL+ Q L F R +Y + + + + G LD + L AV VV RH L Sbjct 6188 LPLTPLQEGLLFHATTTRGGQDSGDLYVVQLDMSVSGPLDRDRLRDAVQAVVDRHPHLVA 6247 Query 1079 VF-----PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIP 1133 F V +P V+ R +L D P +R++ DLA Sbjct 6248 QFCDQFDEPVQIIPADPVMAWRYVEL-----DGGTDPDERIRELCAAERAAVCDLADRPA 6302 Query 1134 LRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVD 1193 R + R A++ H LV HH+ DGWSV L ++ +AS R AP P Y + Sbjct 6303 FRVAMVRTAENRHRLVLTIHHVVLDGWSVPIL---VNETFASLTGQR---LAPAP-PYRN 6355 Query 1194 YTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDW 1253 + W L D D + A A W LAG + P A RG + V Sbjct 6356 FVTW----LADRD-----LDAARAAWGEVLAGFDTPSLVGPPHAMQPAA--RGLTTVA-V 6403 Query 1254 PASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDP--ALDNLV 1311 A + + +AR T V+ A A LL+ L+G+ DVA G ++GRS +++V Sbjct 6404 SAETTRALGELARSCQTTVSTVLQAAWAQLLTWLTGNYDVAFGTTVSGRSAEVAGAESMV 6463 Query 1312 GFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 G +NT+ +R + S A+LL Q+++ E++ + + R H L Sbjct 6464 GLLINTIPVRARITPATSTADLLDQLQSAHNDTLEHEHLSLSEI------HRITGHEKLF 6517 Query 1372 QVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAER----FSEGSEPAG--IGG 1425 + A+++ P L+ + M ++ + D F++ ER + + +G IG Sbjct 6518 DTLFAYENYP--------LETSAMAVNHELSITD--FNVFERNHYPLTMQAALSGDRIGL 6567 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 VEY +F+ ++ L +RL +VLVA+ A P R +SS+D LDG E ARLD+ G+RAVL+ Sbjct 6568 RVEYDAGLFDEHTVEALTKRLERVLVAMTADPARRLSSVDLLDGAEHARLDDVGHRAVLS 6627 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 PAP PVSI M A QVAR P+A A+ D SMTYRELDEA+NRLAH LA GAGPG V Sbjct 6628 RPAPDPVSITDMFADQVARRPDAPAIGWADLSMTYRELDEAANRLAHLLAAEGAGPGTSV 6687 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+VA++AVLKTGAAYLPIDPA P R+ FML DA PVAAVTTAGLRSRL Sbjct 6688 ALLFSRSAQAIVAILAVLKTGAAYLPIDPAAPGARIRFMLADAAPVAAVTTAGLRSRLDE 6747 Query 1606 HDLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLP 1664 D+ +ID+ D + P T P P A +AY++YTSGTTG PKGV +THRNVTRL SL Sbjct 6748 SDVRVIDIEDPRIDRQPPTALPAPEADGVAYLIYTSGTTGAPKGVAVTHRNVTRLIGSLD 6807 Query 1665 ARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL 1724 A L A VW+QCHSY FD S WEI+ LL GGR+V+VPE+V SP DF LL+ E VSVL Sbjct 6808 AGLPAPGVWTQCHSYAFDVSVWEIFAPLLRGGRVVVVPEAVVRSPQDFRALLLDEGVSVL 6867 Query 1725 TQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL 1784 TQTP+AVAML GL+SV+LV+AGEACP +VDR+APGRVM+NAYGPTETT+C AISAPL Sbjct 6868 TQTPSAVAMLDPAGLDSVSLVMAGEACPPEVVDRFAPGRVMVNAYGPTETTMCVAISAPL 6927 Query 1785 RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVA 1844 GSG PPIG PV GAALFVLD WLRPV GV GELY+AG+GV GY RAGLT SRFVA Sbjct 6928 AAGSGTPPIGSPVPGAALFVLDGWLRPVAPGVVGELYVAGSGVAAGYLGRAGLTGSRFVA 6987 Query 1845 CPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQA 1904 CPFG GARMYRTGDLV W ADGQL ++GR D+QVKIRGYRIELGEV ALA L GV QA Sbjct 6988 CPFGEPGARMYRTGDLVFWGADGQLVYVGRADEQVKIRGYRIELGEVQAALARLDGVDQA 7047 Query 1905 VVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNG 1964 VVIAREDRPGDKRLVGY T G DPA R LA RLP Y+VPAAV+ +DALPLT NG Sbjct 7048 VVIAREDRPGDKRLVGYIT----GTADPAEARTALAGRLPVYMVPAAVLGLDALPLTPNG 7103 Query 1965 KLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMR 2024 KLD RALPAPEY GYRAP+ E+ +AG+FA+VLG +RVGVDDSFF+LGGDS++AMR Sbjct 7104 KLDTRALPAPEY-TGRGYRAPSNATEEILAGLFAQVLGADRVGVDDSFFDLGGDSISAMR 7162 Query 2025 VIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVH 2071 +IA IN L DL VR L A + R LSQ LG D TS +V + Sbjct 7163 LIATINAHLAVDLAVRTLFDAPTVRDLSQRLGTDT--TSPEEIVPIQ 7207 Score = 775 bits (2002), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/1054 (49%), Positives = 635/1054 (61%), Gaps = 63/1054 (5%) Query 1023 IPLSFAQRRLWFLDQLQR-----PAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLR 1077 +PL+ Q+ L F R +Y + + + G LD + L AV VV RH +L Sbjct 3639 LPLTPVQQGLLFHAHTVRGGREDATDLYAGQLDIGVTGPLDPDRLREAVHAVVKRHPNLV 3698 Query 1078 TVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSF-DLATEIPLRT 1136 F P Q VI A A + AD R + A R + DLA + P R Sbjct 3699 ARFFDQFDEPVQ-VITADPAPAWQYLELEDGPGADERIRRLCAAERAAVCDLANQPPFRV 3757 Query 1137 WLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAY-ASRCAGRAP-----DWAPLPVQ 1190 L R D H LV HH+ DGWS+ L D+ AAY R AP W + Sbjct 3758 ALIRTGTDRHRLVLTNHHVVLDGWSMPILLGDIFAAYYGQRLPAAAPYRSFVSWLAARDR 3817 Query 1191 YVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLV 1250 W G D+P AL G ++LR +Q S Sbjct 3818 DAARAAWGEVFAG----FDAP----------ALVGRQDQLR---------PGEQGVQSFT 3854 Query 1251 VDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR--SDPALD 1308 + PA + + +AR + T V+ A A LL L+G DV G ++GR P + Sbjct 3855 L--PAELTRAAGELARSCHTTVNTVLQAAYAQLLCWLTGQHDVVFGTTVSGRPAEIPGAE 3912 Query 1309 NLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHH 1368 +VG +NT+ +R L + AELL Q++ ++Q + + R Sbjct 3913 TMVGLLINTVPVRATLTPTTTAAELLEQLQRAHNHTLDHQHLALNEI------HRITGQD 3966 Query 1369 PLIQVMLAWQDNPVGQLNL-GDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAV 1427 L + A+++ P+ L GD + + I +R + + L + G E + V Sbjct 3967 KLFDTLFAYENYPIDAAALSGDHELSITDIASRESTH---YPLTIQAQPGPE---MRLRV 4020 Query 1428 EYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAP 1487 E+ TDVF+A A+ LI+RLR+VL A+ P R +S+ DALD E L+E GNRAVL A Sbjct 4021 EHDTDVFDADAVATLIDRLRRVLDAMTTDPGRPLSATDALDAAEHRLLEEMGNRAVL-AR 4079 Query 1488 APTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVAL 1547 + PVSIP + AAQV R P+A AV C S+TY EL+E++NRLAH L GAGPG VA+ Sbjct 4080 SWVPVSIPGLFAAQVVRTPDAVAVSCAGGSLTYGELEESANRLAHVLIERGAGPGASVAV 4139 Query 1548 LFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHD 1607 + R A+VA++AVLKTGAAYLPIDPA P R+ FML D PVAA+TTA L +LAG+ Sbjct 4140 VLSRSTEAIVAILAVLKTGAAYLPIDPALPAARIEFMLSDTAPVAALTTAALAEKLAGYV 4199 Query 1608 LPIIDVVD-ALAAYPGT-PPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLF--ASL 1663 LP+IDV ALA P T P P P ++A+I+YTSGTTG PKGV ++H NVTRLF + Sbjct 4200 LPVIDVHSPALAGQPATAPAPGPEPEDVAHIIYTSGTTGVPKGVAVSHANVTRLFDAPEV 4259 Query 1664 PARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSV 1723 L + QVW+Q HSY FD S WEIWGALL GGRLV+VPE+VA SP DFH LLV E V+V Sbjct 4260 GVVLGSGQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPEAVARSPKDFHALLVTERVTV 4319 Query 1724 LTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAP 1783 L+QTPAAV ML QGLE ALV+ E PA +VDRWAPGRVM+N YGPTETTI A S P Sbjct 4320 LSQTPAAVRMLSPQGLEGTALVIGAEPVPAEVVDRWAPGRVMVNVYGPTETTIFATASTP 4379 Query 1784 LRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFV 1843 L G PP G V G ALFVLD WLRP P GV GELY+AG GVG+GY RRAGLT SRFV Sbjct 4380 LAAKGGAPPTGSAVPGTALFVLDGWLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFV 4439 Query 1844 ACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQ 1903 ACPFG GARMYRTGDLVCW ADGQL ++GR D QVKIRGYRIE+GE+ + LA L GV Q Sbjct 4440 ACPFGAPGARMYRTGDLVCWGADGQLRYVGRADAQVKIRGYRIEIGEIQSTLAALDGVEQ 4499 Query 1904 AVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVN 1963 AVV+ REDRPGDKRLVGY T G+ +PA LRA LA+RLPGY+VPAA+V + LP+TVN Sbjct 4500 AVVVVREDRPGDKRLVGYLT----GSAEPAALRAALAERLPGYMVPAAIVALPELPMTVN 4555 Query 1964 GKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAM 2023 GKLD RALPAPEY T GYRAP+ P E+ +AGI+A+VLG++RVG+D SFF+LGGDS++AM Sbjct 4556 GKLDTRALPAPEYHGT-GYRAPSTPTEEILAGIYAQVLGVDRVGIDQSFFDLGGDSISAM 4614 Query 2024 RVIAAINTTLNADLPVRALLHASSTRGLSQLLGR 2057 R+IAA+NT L+ L VRAL A + L+ +G Sbjct 4615 RLIAAVNTDLDEYLSVRALFEAPTIAQLAPRIGE 4648 Score = 103 bits (258), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 136/480 (29%), Positives = 207/480 (44%), Gaps = 60/480 (12%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A AY++ TSGTTG PK V ++H ++ ++ G A QC D+SV E Sbjct 6773 ADGVAYLIYTSGTTGAPKGVAVTHRNVTRLIGSLD--AGLPAPGVWTQCHSYAFDVSVWE 6830 Query 631 IFGGAACGARLVRSAAMKT---GDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 IF G R+V D AL+ D + + P+AV L A D++ Sbjct 6831 IFAPLLRGGRVVVVPEAVVRSPQDFRALLLD--EGVSVLTQTPSAVAMLDPAGLDSV--- 6885 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTT- 745 +V+ GEA VD++ + G ++++YGPTE T+ VA P+ T Sbjct 6886 ------SLVMAGEACPPEVVDRF-----APGRVMVNAYGPTETTMCVAISAPLAAGSGTP 6934 Query 746 -------------MDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDG-DGFGTV 791 +DG L RP+ P V GE+ + G VA GYLG G G V Sbjct 6935 PIGSPVPGAALFVLDGWL----RPVAPGVV----GELYVAGSGVAAGYLGRAGLTGSRFV 6986 Query 792 TAADGS-RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSD 850 G R + TGD V A+G V+ GR D VKI G R+++ EV +A V Sbjct 6987 ACPFGEPGARMYRTGDLVFWGADGQLVYVGRADEQVKIRGYRIELGEVQAALARLDGVDQ 7046 Query 851 VAVELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKP 906 V G V + + E A A R+ + +V V+G+ +P P Sbjct 7047 AVVIAREDRPGDKRLVGYITGTADPAEARTALAGRLPVYMVPAA-----VLGLDALPLTP 7101 Query 907 NGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLD 965 NGK+D+ LP P+++ G A + L+ ++++ LG +G D S G S+ Sbjct 7102 NGKLDTRALP-APEYTGRGYR-APSNATEEILAGLFAQVLGADRVGVDDSFFDLGGDSIS 7159 Query 966 LIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPL 1025 +R++ +L L++ L A T +L+ T T + P+ +R A IP+ Sbjct 7160 AMRLIATINAHLAVDLAVRTLFDAPTVRDLSQRLGTDT--TSPEEIVPIQTLKRGAGIPV 7217 Score = 102 bits (254), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 206/795 (26%), Positives = 305/795 (39%), Gaps = 96/795 (12%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L RGA PG + + + + I ++A G Y D A + + + Sbjct 5182 LAGRGAGPGHTVALLFNRSAEAIVAILAALKTGAAYLPVDPAHPAARIGFMLADAAPVAA 5241 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALL----ATKTAYIMPTSGTTGQPKLV 590 +T D+A + HD VD+ + L A AY++ TSGTTG PK V Sbjct 5242 LTTADLADR---LDEHDVAVIDVDDPAVETQPATALPAPSAEDVAYLIYTSGTTGVPKGV 5298 Query 591 RISHGS---LAVFCDA-ISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---R 643 +SH S L DA + A W Q D+SV EIFG G RLV Sbjct 5299 AVSHRSVTGLMASVDARLPDAGVWS------QWHSYGFDVSVWEIFGALLRGGRLVVVPD 5352 Query 644 SAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIR 703 + DL AL LV +++ + +L G A+ V+ GEA Sbjct 5353 AVVRSPEDLHAL---LVGEGVSVLSQTPSAAAMLDPAGLESAAL--------VVAGEACP 5401 Query 704 CSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVF 763 VD+W A+ G ++++YGPTEATV A + T ++ +G P+ +F Sbjct 5402 TDLVDRW----ATSGRVMINAYGPTEATVYAA----ISAPLTPGSGVVPIGSPVAGAALF 5453 Query 764 L-----------AFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRVT 809 + GE+ + G +A GY + F G R + TGD V Sbjct 5454 VLDEYLRPVPPGVVGELYVAGGGLARGYWRRAALTASRF-VACPFGGPGDRMYRTGDLVC 5512 Query 810 VDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFK 865 A+G + GR D VKI G R+++ E+ +AE V AV G V + Sbjct 5513 WGADGQLQYLGRADEQVKIRGYRIELGEIQAALAELRGVRQAAVVAREDRPGDKRLVGYI 5572 Query 866 SQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAG 925 + + E A A R+ +V + V V + +P PNGK+D+ LP P++S A Sbjct 5573 TGKADPAELRARLADRLPAYMVPVAV-----VTLDALPLTPNGKLDARALPA-PEYSDAD 5626 Query 926 LNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLL 984 A L+ I+++ LG IG D S G S+ ++++ R G Sbjct 5627 RYRAPGTPVEEILAGIYAQVLGVERIGVDDSFFDLGGDSISSMQVVTRARAA-GLTCRTR 5685 Query 985 DLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPV 1044 D+ T A LA D + A+P + R +L+ + P Sbjct 5686 DIFVEQTVARLARVVGVADGDAD-------ATDEGTGALPATPIIR---WLEGVDGPVEE 5735 Query 1045 YNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP-AVDGVPRQLVIEARRADLGCDI 1103 +N + + + + A + ++ RH LR DG V EA D + Sbjct 5736 FNQTMVVAAPAGVTEADVVAVLQALLDRHAMLRLRLDDGADGWALT-VPEAGSVDAAERL 5794 Query 1104 VDATAWPADRLQRAIEEAARHSFDLATEIPLRT-WLFRIADDEHVLVAVAHHIAADGWSV 1162 D L A AAR D A + L W A LV + HH+A DG S Sbjct 5795 RTV-----DDLSEAAVLAARSRLDPARGVMLSALW----AAGTGQLVLIIHHLAVDGVSW 5845 Query 1163 APLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENA 1222 L DL+ A+A G+ LP + W + D +A Q W+ Sbjct 5846 RILLEDLNIAWAQHRGGQP---VALPPGGTSFARWAALLAEHAHAPD--VAGQAGAWKRI 5900 Query 1223 LAGMPERLRLPTARP 1237 A P LP RP Sbjct 5901 AATPPA---LPAVRP 5912 >gi|118462635|ref|YP_882425.1| linear gramicidin synthetase subunit B [Mycobacterium avium 104] gi|118163922|gb|ABK64819.1| linear gramicidin synthetase subunit B [Mycobacterium avium 104] Length=2552 Score = 1505 bits (3897), Expect = 0.0, Method: Compositional matrix adjust. Identities = 856/1511 (57%), Positives = 1029/1511 (69%), Gaps = 71/1511 (4%) Query 1023 IPLSFAQRRLWFLDQL-QRPAP-VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F Q P VY + + + + G LD+ L AV VV RH +L F Sbjct 1092 LPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGALDSHRLHDAVHTVVNRHPNLAARF 1151 Query 1081 PAVDGVPRQLV-----IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+V + R LG + VD P +++ DLA R Sbjct 1152 CPQYGEPVQVVPADPVMAWRYIQLGPEDVD----PEQKVEELCAAERAAVSDLANRPAFR 1207 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R AD+ H V HHI DGWS+ L ++ A Y D P P Y Y Sbjct 1208 AALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYG-------DQLPAPATYRSYL 1260 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVD--- 1252 W L D S AAQ A W L G T P R V+ Sbjct 1261 TW----LAGQDRS----AAQAA-WRQVLDG------FDTPTLVGPAGRMRLGRRAVESYR 1305 Query 1253 WPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNL 1310 A + + +AR + T V+ AG A LL +L+G DVA G ++GR +D A +++ Sbjct 1306 LSADTTRALGELARACHTTVNTVLQAGWAQLLMRLTGQHDVAFGTAVSGRPADLAGAESM 1365 Query 1311 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL 1370 VG +NT+ +R N + + A+LL Q++ E++ + + R H L Sbjct 1366 VGLLINTVPVRANTHAETTVADLLDQLQQHHNDTLEHEHLALSEI------HRVTGHDAL 1419 Query 1371 IQVMLAWQDNPVG-QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 + +++ P+ + LG + + I T R + L+ G E +G VE+ Sbjct 1420 FDTLFLYENYPIDTSVPLGFHE---LAITDVTNREYNHYPLSVMALPGRE---LGLRVEF 1473 Query 1430 RTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAP 1489 TDVF+A I+ L ER ++VL + A P R ++S++ +D E LD WGNR VL+ PA Sbjct 1474 DTDVFDAAGIEKLTERFQRVLSEMTADPTRRLTSLEVMDEAEHELLDAWGNRPVLSQPA- 1532 Query 1490 TPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLF 1549 T SIP + AAQVAR P+A A+ SM+YRELDEASNRLAH L GAGPGECVALLF Sbjct 1533 TGTSIPALFAAQVARTPDAAALTFQGRSMSYRELDEASNRLAHLLIEEGAGPGECVALLF 1592 Query 1550 ERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLP 1609 R A A+V+++AVLKTGAAYLPIDPA P R+ F+LGDA PVA VTTA LRSRL G Sbjct 1593 SRSAEAIVSILAVLKTGAAYLPIDPALPAARIEFLLGDAEPVAVVTTAALRSRLDGCKPS 1652 Query 1610 IIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS 1668 ++DV D AL P P+P++ N+AY++YTSGTTG PKGV ++H NV +L SL A L Sbjct 1653 VVDVDDPALDGQPSAALPVPSSDNIAYLIYTSGTTGVPKGVAVSHDNVAQLVESLHADLP 1712 Query 1669 AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 VW+Q HS FD S EIWGALL GGRLV+VPESVAASP++ H LLVAE V+VL+QTP Sbjct 1713 EGGVWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHDLLVAEGVTVLSQTP 1772 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 +AV ML +GL+S ALVVAGEACP +VDRWAPGRVM+NAYGPTE T+ AA+S PL+PG+ Sbjct 1773 SAVGMLSPEGLDSTALVVAGEACPVEIVDRWAPGRVMINAYGPTEATVYAAMSTPLQPGT 1832 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 G PIG PV AALFVLD WLRP P GV GELYIAG GV GY RR+GLTASRFVACPFG Sbjct 1833 GSAPIGSPVPRAALFVLDRWLRPAPPGVVGELYIAGHGVATGYARRSGLTASRFVACPFG 1892 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 G GARMYRTGDLV W DGQLE+LGR D+QVK+RGYRIELGEV ALA L GV QA VIA Sbjct 1893 GPGARMYRTGDLVRWNQDGQLEYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIA 1952 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 REDRPGDKRLVGY T G DP G+R QLA+RLP Y+VPAAVVV+DALPLTVNGKLD Sbjct 1953 REDRPGDKRLVGYIT----GTADPVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDK 2008 Query 1969 RALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 RALPAPEY G Y AP P E+TVAGIFARVLG+ERV +DDSFFELGGDSL+AMRVIA Sbjct 2009 RALPAPEYRKRGGEYIAPTNPTEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIA 2068 Query 2028 AINTTLNADLPVRALLHASSTRGLSQLL--GRDARPTSDPRLVSVHGDNPTEVHASDLTL 2085 INT ++ L VR L + S R LSQ + G DA + P +VHG + EV+A DLTL Sbjct 2069 EINTAVDGALSVRTLFDSQSVRALSQRITSGADAENAAGPGFAAVHGADAKEVYARDLTL 2128 Query 2086 DRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAE 2144 D+F+DA TL+TA LPGPSPE+RTVLLTGATGFLGRYLVLE L +L+ VDG+LICLVRA Sbjct 2129 DKFLDATTLSTAPTLPGPSPEVRTVLLTGATGFLGRYLVLEWLEQLEQVDGKLICLVRAR 2188 Query 2145 SDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDL 2204 SDE+A RLEKTF++GDPELLRHF+ELA + L+VVAGDK + +LGLD+ W++LA+TVDL Sbjct 2189 SDEEAWGRLEKTFNTGDPELLRHFQELAEEHLQVVAGDKGQANLGLDEQTWQQLADTVDL 2248 Query 2205 IVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTED 2263 IVDSAA+VN PY ELF PNV GTAELIR+ALTT+ KPF YVST+DVG IEPSAFTED Sbjct 2249 IVDSAAVVNGVLPYSELFTPNVGGTAELIRLALTTRKKPFAYVSTSDVGRQIEPSAFTED 2308 Query 2264 ADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQL 2323 ADIRVIS TR +DG +A GYG SKWAGEVLLREA+DLC LPV+VFR MILADTSYAGQL Sbjct 2309 ADIRVISATRVIDGSYANGYGNSKWAGEVLLREAHDLCGLPVSVFRSDMILADTSYAGQL 2368 Query 2324 NMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSS 2383 N++D TRM+LS++ATG AP+SFY D++GNRQR+HFD LPV FVAEAIA LGA+V Sbjct 2369 NVTDIFTRMILSIVATGTAPKSFYRLDADGNRQRSHFDALPVEFVAEAIAKLGAQV---- 2424 Query 2384 LAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRH 2443 + GF TYHVMNPHDDGIGLDEYVDWLIEAGYPI R+DDF EWLQRFE L LP+RQR++ Sbjct 2425 MDGFETYHVMNPHDDGIGLDEYVDWLIEAGYPIERVDDFGEWLQRFETGLRGLPERQRQN 2484 Query 2444 SVLPMLLAS--NSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIIN 2501 SVL MLL + + LQ +P RG APTDRFRAAV+ AKVGSD DIPH+SAP I+ Sbjct 2485 SVLQMLLLLLRDPKNLQLAEPARGAFAPTDRFRAAVQEAKVGSDN---DIPHISAPVIVK 2541 Query 2502 YVTNLQLLGLL 2512 YVT+LQLLGLL Sbjct 2542 YVTDLQLLGLL 2552 Score = 763 bits (1970), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/576 (69%), Positives = 449/576 (78%), Gaps = 11/576 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R + SID LDG E RLDEWGNRA+LT P P SIP M AAQVAR EA A+ SM Sbjct 7 RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAPASIPGMFAAQVARSAEAVALSFEGRSM 66 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TYRELDEASNRLAH LA GA PGECVALLF R A+V+++AVLKTGAAYLPIDPA P Sbjct 67 TYRELDEASNRLAHLLAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPA 126 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPP----PMPAAVNLA 1634 R+ FMLGDA P+AAVTTAGLR RL G DLP+IDV +A A T P P P+ ++A Sbjct 127 ARMEFMLGDATPIAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIA 186 Query 1635 YILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA--QVWSQCHSYGFDASAWEIWGAL 1692 Y++YTSGTTG PKGV +THRNVT +L +L + QVWSQ HS FD S WE WGAL Sbjct 187 YMIYTSGTTGTPKGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGAL 246 Query 1693 LGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACP 1752 L GGRLV+VPESVA SP+D H LLVAE V+VL+QTP+AV ML +GL+S ALVVAGEACP Sbjct 247 LHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACP 306 Query 1753 AALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 A +VDRWAPGRVM+NAYGPTE T+ AA+SAPL SG PPIG PV GAALFVLD WLRP Sbjct 307 AEVVDRWAPGRVMINAYGPTEATVYAAMSAPLTAESGAPPIGSPVPGAALFVLDKWLRPA 366 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELYIAG GV GY RRAGLTASRFVACPFGG GARMYRTGDLV W ADGQL++L Sbjct 367 PEGVVGELYIAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWGADGQLQYL 426 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLVGY T G DP Sbjct 427 GRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYIT----GTADP 482 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEK 1991 A LR QL +RLP Y+VPAAVVV+++LPLTVNGKLD RALPAPEY G YRAP+ E+ Sbjct 483 AELRTQLGKRLPAYMVPAAVVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRAPSNHTEE 542 Query 1992 TVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +A I+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 543 ILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 578 Score = 107 bits (268), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 180/734 (25%), Positives = 284/734 (39%), Gaps = 74/734 (10%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L ++GAAPG+ + +D+ I ++A G Y D A + + GD Sbjct 82 LAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPAARMEFML---GDATP 138 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLAT-------KTAYIMPTSGTTGQP 587 + V A + + G D VDE ++ + AY++ TSGTTG P Sbjct 139 IAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIAYMIYTSGTTGTP 198 Query 588 KLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAM 647 K V ++H ++ F + G Q L D+SV E +G G RLV Sbjct 199 KGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGALLHGGRLVVVPES 258 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 G L D LVA T++ + +L +G +D+ +V+ GEA V Sbjct 259 VAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEG--LDSTA------LVVAGEACPAEVV 310 Query 708 DKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL--- 764 D+W + G ++++YGPTEATV A + T + +G P+ +F+ Sbjct 311 DRW-----APGRVMINAYGPTEATVYAA----MSAPLTAESGAPPIGSPVPGAALFVLDK 361 Query 765 --------AFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE 813 GE+ I G VA GY G+ F G R + TGD V A+ Sbjct 362 WLRPAPEGVVGELYIAGRGVATGYARRAGLTASRF-VACPFGGPGARMYRTGDLVRWGAD 420 Query 814 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRT 869 G + GR D VKI G R+++ E+ +A V AV G V + + Sbjct 421 GQLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTA 480 Query 870 REGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTA 929 E R+ +V VV + ++P NGK+D LP AG A Sbjct 481 DPAELRTQLGKRLPAYMVPAA-----VVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRA 535 Query 930 ETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIG 988 + L+ I+++ LG +G D S G S+ ++++ R G D+ Sbjct 536 PSNHTEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGVICRPRDVFV 594 Query 989 ADTAANLADYAPTPDAPTGEDRFRPLVAAQRPA-AIPLSFAQRRLWFLDQLQRPAPVYNM 1047 T A LA A G D + + P A P+ + +L +Q P +N Sbjct 595 EQTVARLARV-----ASDGADEEQVVDEGIGPVQATPI------MRWLQTVQGPIDDFNQ 643 Query 1048 AVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDAT 1107 + L + + + + ++ RH LR L + D + + Sbjct 644 TMVLAAPSGVTADDVAVVLQALLDRHPMLRLRVEDDGAGGWNLQAPEPGSVRAADCLQSV 703 Query 1108 AWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAVAHHIAADGWSVAPLT 1166 D L A+ AAR + + + W A + L + HH+A DG S L Sbjct 704 ----DTLSDAVLVAARSRLNPGAGVMVSAVW----ASETSQLALIIHHVAVDGVSWRTLI 755 Query 1167 ADLSAAYASRCAGR 1180 DL+ A+A +G+ Sbjct 756 EDLNIAWAQHHSGQ 769 Score = 96.7 bits (239), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 148/544 (28%), Positives = 218/544 (41%), Gaps = 49/544 (9%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L++ GA PG+ + + + I ++A G Y D A + R + GD Sbjct 1577 LIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALP-AARIEFLL--GDAEP 1633 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALL----ATKTAYIMPTSGTTGQPKLV 590 V VV AA + + G VD+ A L + AY++ TSGTTG PK V Sbjct 1634 VAVVTTAALRSRLDGCKPSVVDVDDPALDGQPSAALPVPSSDNIAYLIYTSGTTGVPKGV 1693 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTG 650 +SH ++A +++ G Q L D+SV EI+G G RLV Sbjct 1694 AVSHDNVAQLVESLHADLPEGG--VWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAA 1751 Query 651 DLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKW 710 L D LVA T++ + +L +G +D+ +V+ GEA VD+W Sbjct 1752 SPDELHDLLVAEGVTVLSQTPSAVGMLSPEG--LDSTA------LVVAGEACPVEIVDRW 1803 Query 711 LESAASQGISLLSSYGPTEATVVATFLPIVCDQT--------TMDGALL---RLGRPILP 759 + G ++++YGPTEATV A + T AL R RP P Sbjct 1804 -----APGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPP 1858 Query 760 NTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFP 816 V GE+ I G VA GY G+ F G R + TGD V + +G Sbjct 1859 GVV----GELYIAGHGVATGYARRSGLTASRF-VACPFGGPGARMYRTGDLVRWNQDGQL 1913 Query 817 VFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDA 876 + GR D VK+ G R+++ EV +A V AV G +R Sbjct 1914 EYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPG----DKRLVGYITGT 1969 Query 877 AAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ 933 A IR+ L + VV + +P NGK+D LP G A T Sbjct 1970 ADPVGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNP 2029 Query 934 RAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTA 992 ++ I++R LG + D S G SL +R++ E + LS+ L + + Sbjct 2030 TEETVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIAEINTAVDGALSVRTLFDSQSV 2089 Query 993 ANLA 996 L+ Sbjct 2090 RALS 2093 >gi|342858826|ref|ZP_08715481.1| linear gramicidin synthetase subunit B [Mycobacterium colombiense CECT 3035] gi|342134530|gb|EGT87710.1| linear gramicidin synthetase subunit B [Mycobacterium colombiense CECT 3035] Length=2549 Score = 1474 bits (3817), Expect = 0.0, Method: Compositional matrix adjust. Identities = 848/1512 (57%), Positives = 1013/1512 (67%), Gaps = 73/1512 (4%) Query 1023 IPLSFAQRRLWFLDQL-QRPAP-VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F Q P VY + + + + G LD+ L AV VV RH +L F Sbjct 1089 LPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGELDSHRLHDAVHTVVSRHPNLAARF 1148 Query 1081 PAVDGVPRQL-----VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+ V+ R LG + +D P R++ DLA R Sbjct 1149 CPQFGEPVQVIPADPVMAWRYIQLGAEDLD----PEQRVEELCAAERAAVSDLANRPAFR 1204 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R AD+ + V HHI DGWS+ L ++ A Y D P P Y Y Sbjct 1205 AALIRTADNRYRFVLTNHHIVMDGWSLPILLREILANYYG-------DQLPAPATYRSYL 1257 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPT-ARPYPPVADQRGASLVVDWP 1254 W L D + AAQ A W L G PT P + R A Sbjct 1258 TW----LAGQDRT----AAQAA-WRQVLEG----FDTPTLVGPAGRMKLGRRAVESYRLS 1304 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPAL--DNLVG 1312 A + +AR + T V+ A A LL +L+G DVA G ++GR + +++VG Sbjct 1305 AETTLALGELARSCHTTVNTVLQAAWAQLLMRLTGQHDVAFGTAVSGRPADLIGAESMVG 1364 Query 1313 FFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT-HHPLI 1371 +NT+ +R ++ + + A++L Q L + N + E L L +T H L Sbjct 1365 LLINTVPVRASITSETTVADVLEQ-----LQQHHNDTLEHEHLA--LSDIHHVTGHDALF 1417 Query 1372 QVMLAWQDNPVGQ---LNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVE 1428 + +++ P+ L +L T + T R + L+ G E +G VE Sbjct 1418 DTLFLYENYPIDTSVPLGFHELAITDV-----TNREYNHYPLSVMALPGRE---LGLRVE 1469 Query 1429 YRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPA 1488 + TDVF+A I+ L ER ++VL + P R + S+D +D E A LDE GNRAVL+ PA Sbjct 1470 FDTDVFDAAGIEKLTERFQRVLSEMTVDPTRKLMSLDVVDEHEHAWLDERGNRAVLSQPA 1529 Query 1489 PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALL 1548 T SIP M AAQVA P+A A+ SMTYRELDEA+NR+AH L GAGPGE VALL Sbjct 1530 -TGKSIPAMFAAQVASTPDAAALTFDGRSMTYRELDEAANRMAHLLTEEGAGPGERVALL 1588 Query 1549 FERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDL 1608 F R A A+V+++AVLKTGAAYLPIDPA P R+ F+L DA PVA VTTAGLR RL G + Sbjct 1589 FSRSADAIVSILAVLKTGAAYLPIDPALPAARIEFLLADAEPVAVVTTAGLRDRLDGCNP 1648 Query 1609 PIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARL 1667 +IDV D LAA P T P+P++ N+AY++YTSGTTG PKGV +TH NV +L +L A L Sbjct 1649 TVIDVDDPELAAQPSTALPIPSSDNIAYVIYTSGTTGVPKGVAVTHENVAQLLETLHADL 1708 Query 1668 SAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQT 1727 A VW+Q HS FD S EIWGALL GGRLV+VPESVAASP++ H LLV+E V+VL+QT Sbjct 1709 PEAGVWAQWHSLVFDVSVHEIWGALLHGGRLVVVPESVAASPDELHALLVSEGVTVLSQT 1768 Query 1728 PAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPG 1787 P+AV ML +GLES ALVVAGEACP +VDRWAPGRVM+NAYGPTE T+ AA+SAPL G Sbjct 1769 PSAVGMLSPEGLESTALVVAGEACPVEVVDRWAPGRVMINAYGPTEATVYAAMSAPLASG 1828 Query 1788 SGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPF 1847 +G PIG PV AALFVLD WLRP P GV GELYIAG GV GY RR GLTA RFVACPF Sbjct 1829 TGSAPIGSPVPRAALFVLDRWLRPTPEGVVGELYIAGHGVATGYSRRPGLTAGRFVACPF 1888 Query 1848 GGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVI 1907 GG GARMYRTGDLV W DGQLE+LGR D+QVK+RGYRIELGEV ALA L GV QA VI Sbjct 1889 GGPGARMYRTGDLVRWGRDGQLEYLGRADEQVKLRGYRIELGEVQAALASLEGVEQAAVI 1948 Query 1908 AREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLD 1967 AREDRPGDKRLVGY T G DP G+R QLA RLP Y+VPAAVV +DALPLTVNGKLD Sbjct 1949 AREDRPGDKRLVGYIT----GTADPVGIRIQLADRLPAYMVPAAVVALDALPLTVNGKLD 2004 Query 1968 HRALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 RALPAPEY G Y APA P E+ VA IF RVLG+ERV V+DSFFELGGDSL+AMRVI Sbjct 2005 KRALPAPEYQKRGGEYVAPADPTEEIVADIFGRVLGMERVSVEDSFFELGGDSLSAMRVI 2064 Query 2027 AAINTTLNADLPVRALLHASSTRGLSQLL--GRDARPTSDPRLVSVHGDNPTEVHASDLT 2084 A INT ++ L VR L + S R L+ + G D + P +VHG + EV A DLT Sbjct 2065 AEINTAVDGALSVRTLFDSQSVRALAHRITSGADTEGAAGPGFAAVHGADAKEVFARDLT 2124 Query 2085 LDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRA 2143 LD+FIDA TL+ A LPGPS E+RTVLLTGATGFLGRYL LE L +L+ VDG+LICLVRA Sbjct 2125 LDKFIDATTLSNAPALPGPSAEVRTVLLTGATGFLGRYLALEWLEQLEQVDGKLICLVRA 2184 Query 2144 ESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVD 2203 SDEDA RRLEKTFDSGDP+LLRHF+ELA + L+VVAGDK + +LGLD W+RLA+TVD Sbjct 2185 RSDEDAWRRLEKTFDSGDPDLLRHFQELAEEHLQVVAGDKGQANLGLDDETWQRLADTVD 2244 Query 2204 LIVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTE 2262 LIVDSAA+VN PY+ELF PNV GTAELIR+A+TTK KP+ YVST+DVG I+P+ FTE Sbjct 2245 LIVDSAAVVNGVLPYNELFTPNVGGTAELIRLAITTKKKPYAYVSTSDVGRQIDPAQFTE 2304 Query 2263 DADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQ 2322 D DIRVIS R +DGG+A GYG SKWAGEVLLREANDLC LPV+VFR MILADT+YAGQ Sbjct 2305 DGDIRVISARRVIDGGYANGYGNSKWAGEVLLREANDLCGLPVSVFRSDMILADTTYAGQ 2364 Query 2323 LNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGS 2382 LN++D TRM+LS++ATG AP+SFY+ D++GNRQ AHFDGLPV FVAEAIA LGA+V Sbjct 2365 LNVADIFTRMILSVVATGTAPKSFYQLDADGNRQSAHFDGLPVEFVAEAIAKLGAQV--- 2421 Query 2383 SLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRR 2442 + GF TYHVMNPHDDGIGLDEYVDWLIEAGYPI R+ DF EWLQRFE L LP+RQR+ Sbjct 2422 -MDGFETYHVMNPHDDGIGLDEYVDWLIEAGYPIERVGDFGEWLQRFETGLRGLPERQRQ 2480 Query 2443 HSVLPM--LLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTII 2500 +SVL M LL + LQP +P RG APTDRFRAAV+ AKVGSD DIPHVSA I+ Sbjct 2481 NSVLQMLTLLLREPKNLQPAEPARGAFAPTDRFRAAVQEAKVGSDN---DIPHVSASVIV 2537 Query 2501 NYVTNLQLLGLL 2512 YVT+LQLLGLL Sbjct 2538 KYVTDLQLLGLL 2549 Score = 756 bits (1952), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/573 (68%), Positives = 447/573 (79%), Gaps = 8/573 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R + SID LDG E RLDEWGNRAVLT P P+SIP+M A QVAR P++ A+ GD S+ Sbjct 7 RRLLSIDLLDGGEHDRLDEWGNRAVLTKPVKAPLSIPEMFATQVARAPQSVALTFGDRSL 66 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TY+ELDEA+NRLAH LA GA PGECVALLF R A A+++++AVLKTGAAYLPIDPA P Sbjct 67 TYQELDEAANRLAHLLAEQGARPGECVALLFSRSAEAIISILAVLKTGAAYLPIDPALPS 126 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA-AYPGTPPPMPAAVNLAYIL 1637 R+ FMLGDA P+A VTTA LR+RL G DLP+IDV +A A P + PA ++AY++ Sbjct 127 ARMEFMLGDATPIAVVTTASLRTRLDGFDLPVIDVDEAAADGQPSSALEGPAPEDIAYMI 186 Query 1638 YTSGTTGEPKGVGITHRNVTRLFASLPARLSAA--QVWSQCHSYGFDASAWEIWGALLGG 1695 YTSGTTG PKGV +THRNVT +L A L +VWSQ HS FD S WEIWGALL G Sbjct 187 YTSGTTGTPKGVAVTHRNVTEFVRTLHADLPTGPGKVWSQWHSLVFDVSVWEIWGALLHG 246 Query 1696 GRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAAL 1755 GRLV+VPESVA SP++ H LLVAE V+VL+QTP+AV ML +GL+ ALVVAGEACPA + Sbjct 247 GRLVVVPESVAGSPDELHALLVAEKVNVLSQTPSAVGMLSPEGLDDTALVVAGEACPAEV 306 Query 1756 VDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAG 1815 VDRWAPGRVM+NAYGPTE T+ AA+S L SG PPIG PV GAALFVLD WLRP P G Sbjct 307 VDRWAPGRVMINAYGPTEATVYAAMSTALAGDSGAPPIGSPVPGAALFVLDKWLRPAPEG 366 Query 1816 VAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRT 1875 V GELY+AG GV GY RRAGLTASRFVACPFGG GARMYRTGDLV W ADGQL++LGR Sbjct 367 VVGELYVAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWGADGQLQYLGRA 426 Query 1876 DDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGL 1935 D+QVKIRGYRIELGE+ +ALA L GV QA VIAREDRPGDKRLVGY T G DP L Sbjct 427 DEQVKIRGYRIELGEIQSALASLEGVDQAAVIAREDRPGDKRLVGYIT----GTADPTEL 482 Query 1936 RAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEKTVA 1994 R QL +RLP Y+VPAAVVV++ LPLTVNGKLD RALPAPEY G YRAP E+ +A Sbjct 483 RTQLGKRLPAYMVPAAVVVLETLPLTVNGKLDKRALPAPEYHKRGGQYRAPGNHTEEILA 542 Query 1995 GIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 GI+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 543 GIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 575 Score = 100 bits (249), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 189/746 (26%), Positives = 293/746 (40%), Gaps = 101/746 (13%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L ++GA PG+ + + + I ++A G Y D A S R + GD Sbjct 82 LAEQGARPGECVALLFSRSAEAIISILAVLKTGAAYLPIDPALP-SARMEFML--GDATP 138 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLA----TKTAYIMPTSGTTGQPKLV 590 + VV A+ + + G D VDE + L AY++ TSGTTG PK V Sbjct 139 IAVVTTASLRTRLDGFDLPVIDVDEAAADGQPSSALEGPAPEDIAYMIYTSGTTGTPKGV 198 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAM 647 ++H ++ F + G Q L D+SV EI+G G RLV S A Sbjct 199 AVTHRNVTEFVRTLHADLPTGPGKVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVAG 258 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 +L AL LVA + ++ + +L +G +D +V+ GEA V Sbjct 259 SPDELHAL---LVAEKVNVLSQTPSAVGMLSPEG--LDDTA------LVVAGEACPAEVV 307 Query 708 DKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL--- 764 D+W + G ++++YGPTEATV A + D +G P+ +F+ Sbjct 308 DRW-----APGRVMINAYGPTEATVYAAMSTALAG----DSGAPPIGSPVPGAALFVLDK 358 Query 765 --------AFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSRRRAFATGDRVTVDAE 813 GE+ + G VA GY G+ F G R + TGD V A+ Sbjct 359 WLRPAPEGVVGELYVAGRGVATGYARRAGLTASRF-VACPFGGPGARMYRTGDLVRWGAD 417 Query 814 GFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRT 869 G + GR D VKI G R+++ E+ +A V AV G V + + Sbjct 418 GQLQYLGRADEQVKIRGYRIELGEIQSALASLEGVDQAAVIAREDRPGDKRLVGYITGTA 477 Query 870 REGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLP------RLPQWSA 923 E R+ +V VV + +P NGK+D LP R Q+ A Sbjct 478 DPTELRTQLGKRLPAYMVPAA-----VVVLETLPLTVNGKLDKRALPAPEYHKRGGQYRA 532 Query 924 AGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLS 982 G +T E L+ I+++ LG +G D S G S+ ++++ R G Sbjct 533 PGNHTEEI------LAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGVMCR 585 Query 983 LLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPA-AIPLSFAQRRLWFLDQLQRP 1041 D+ T A LA A G D + P A P+ + +L +Q P Sbjct 586 PRDVFVEQTVARLARV-----ATDGADEDDVVDEGIGPVLATPI------MHWLQTVQGP 634 Query 1042 APVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRT-VFPAVDG-----VPRQLVIEAR 1095 +N + L + +E + + ++ RH LR V DG P ++A Sbjct 635 IDDFNQTMVLAAPAGVTSEDVALVLQALLDRHPMLRLRVEDDGDGGWSLHAPEPGTVQA- 693 Query 1096 RADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAVAHH 1154 D + + ++L AAR + + + W A + L + HH Sbjct 694 -----ADCLQSV----EQLSDETLVAARSRLNPGAGVMVSAVW----ATETSQLALIIHH 740 Query 1155 IAADGWSVAPLTADLSAAYASRCAGR 1180 +A DG S L DL+ A+A +G+ Sbjct 741 VAVDGVSWRTLIEDLNIAWAQHHSGQ 766 Score = 92.4 bits (228), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 148/557 (27%), Positives = 217/557 (39%), Gaps = 75/557 (13%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCD-------------TADEISV 521 L + GA PG+ + + I ++A G Y D A+ ++V Sbjct 1574 LTEEGAGPGERVALLFSRSADAIVSILAVLKTGAAYLPIDPALPAARIEFLLADAEPVAV 1633 Query 522 RTNA-ITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 T A + + DG TV+DV +LA L + + AY++ T Sbjct 1634 VTTAGLRDRLDGCNPTVIDVDDPELAAQPSTALPIPSSDNI-------------AYVIYT 1680 Query 581 SGTTGQPKLVRISHGSLAVFCDAIS----RAYGWGAHDTVLQCAPLTSDISVEEIFGGAA 636 SGTTG PK V ++H ++A + + A W Q L D+SV EI+G Sbjct 1681 SGTTGVPKGVAVTHENVAQLLETLHADLPEAGVWA------QWHSLVFDVSVHEIWGALL 1734 Query 637 CGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLR 693 G RLV S A +L AL LV+ T++ + +L +G A+ Sbjct 1735 HGGRLVVVPESVAASPDELHAL---LVSEGVTVLSQTPSAVGMLSPEGLESTAL------ 1785 Query 694 QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQT--------T 745 V+ GEA VD+W + G ++++YGPTEATV A + T Sbjct 1786 --VVAGEACPVEVVDRW-----APGRVMINAYGPTEATVYAAMSAPLASGTGSAPIGSPV 1838 Query 746 MDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGSRRRAFA 803 AL L R + P T GE+ I G VA GY G G A G R + Sbjct 1839 PRAALFVLDRWLRP-TPEGVVGELYIAGHGVATGYSRRPGLTAGRFVACPFGGPGARMYR 1897 Query 804 TGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVW 863 TGD V +G + GR D VK+ G R+++ EV +A V AV G Sbjct 1898 TGDLVRWGRDGQLEYLGRADEQVKLRGYRIELGEVQAALASLEGVEQAAVIAREDRPG-- 1955 Query 864 FKSQRTREGEQDAAAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKIDSDNLPRLPQ 920 +R A IR+ L + VV + +P NGK+D LP Sbjct 1956 --DKRLVGYITGTADPVGIRIQLADRLPAYMVPAAVVALDALPLTVNGKLDKRALPAPEY 2013 Query 921 WSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW 979 G A ++ I+ R LG + + S G SL +R++ E + Sbjct 2014 QKRGGEYVAPADPTEEIVADIFGRVLGMERVSVEDSFFELGGDSLSAMRVIAEINTAVDG 2073 Query 980 RLSLLDLIGADTAANLA 996 LS+ L + + LA Sbjct 2074 ALSVRTLFDSQSVRALA 2090 >gi|296164403|ref|ZP_06846978.1| linear gramicidin synthetase subunit C [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900243|gb|EFG79674.1| linear gramicidin synthetase subunit C [Mycobacterium parascrofulaceum ATCC BAA-614] Length=2548 Score = 1467 bits (3798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 841/1488 (57%), Positives = 1017/1488 (69%), Gaps = 68/1488 (4%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV-----IEARRAD 1098 VY + + + + G LD L AV VV RH +L F G P Q++ + R Sbjct 1110 VYAVQLGITVTGDLDPHRLREAVHAVVNRHPNLAARFCPQFGQPVQVIPADPAMAWRYIQ 1169 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 LG + +D P +++++ DLA R L R AD+ H V HHI D Sbjct 1170 LGAEDLD----PDEKIEQLCAAERAAVSDLANRPAFRAALIRTADNRHRFVLTNHHIVMD 1225 Query 1159 GWSVAPLTAD-LSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLA 1217 GWS+ L + L++ Y R P P Y Y W L D + A A Sbjct 1226 GWSLPILLREILTSYYGERL--------PAPASYRSYLTW----LAAQDRT-----AARA 1268 Query 1218 YWENALAGMPE-RLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVV 1276 W LAG L P AR ++ R PA + + +AR + T V+ Sbjct 1269 AWGEVLAGFDTPTLVGPPAR----LSVGRRGVESYRLPAETTRALGELARSCHTTINTVL 1324 Query 1277 AAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 A A LL +++G DVA G ++GR +D A +++VG +NT+ +R ++ + AELL Sbjct 1325 QAAWAQLLMRVTGQYDVAFGTAVSGRPADLAGAESMVGLLINTVPVRAHITAATTVAELL 1384 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVG-QLNLGDLQAT 1393 Q++ E++ + + R H L + +++ P+ + LG + Sbjct 1385 QQLQNAHNNTLEHEHLALNEI------HRVTGHDLLFDTLFLYENYPIDTSVPLGFHE-- 1436 Query 1394 PMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAV 1453 + I T R + LA G E +G VE+ T VF+ I+ +IER +VL A+ Sbjct 1437 -LAITDVTNREYNHYPLAVMALPGRE---LGLRVEFDTSVFDTAGIESMIERFERVLGAM 1492 Query 1454 AAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC 1513 A + +S++D LD ERARLDEWGNRAVLTAP SIP + A QVAR+P+A A+ Sbjct 1493 TADSSQRLSAMDVLDLGERARLDEWGNRAVLTAPVRAAASIPALFAKQVARVPDAVALTF 1552 Query 1514 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPID 1573 S+TYRELDEA+NRLAH LA GA PGE VALLF R A A+V+++AVLKTGAAYLPID Sbjct 1553 EGRSLTYRELDEAANRLAHLLAEHGARPGESVALLFSRSAEAIVSILAVLKTGAAYLPID 1612 Query 1574 PANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA-AYPGTPPPMPAAVN 1632 PA P R+ F+L DA PVAAVTTA LR RL G DL ++DV A A P T P P+ + Sbjct 1613 PAVPSARIEFVLSDAAPVAAVTTADLRPRLDGFDLVVVDVDAAPADTRPATALPAPSPED 1672 Query 1633 LAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGAL 1692 +AY++YTSGTTG PKGV +TH N T+L L A L VW+Q HS FD S EI+GAL Sbjct 1673 IAYVIYTSGTTGVPKGVAVTHHNATQLLEKLHADLPDPGVWAQWHSLVFDVSVHEIFGAL 1732 Query 1693 LGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACP 1752 L GGRLV+VPESVA SP D H LLVAE+V+VL+QTP+AV ML +GLES ALVVAGEACP Sbjct 1733 LHGGRLVVVPESVAGSPKDLHALLVAENVTVLSQTPSAVGMLSPEGLESTALVVAGEACP 1792 Query 1753 AALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 +V+RWAPGRVM+NAYGPTE T+ AA+SAPL +G P IG PV GAALFVLD WLRP Sbjct 1793 PEVVERWAPGRVMINAYGPTEGTVYAAMSAPLNADAGAP-IGSPVPGAALFVLDKWLRPA 1851 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELYIAG GV GY RR+GLTASRFVACPFG G+RMYRTGDLV W ADGQL++L Sbjct 1852 PEGVVGELYIAGRGVACGYARRSGLTASRFVACPFGAPGSRMYRTGDLVRWGADGQLQYL 1911 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVKIRGYRIELGE+ ALA L GV QA VIAREDRPGDKRLVGY T G DP Sbjct 1912 GRVDEQVKIRGYRIELGEIQAALAGLDGVEQAAVIAREDRPGDKRLVGYIT----GTADP 1967 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEK 1991 A +RAQL +RLP Y+VP AVVV+DALPLTVNGKLD RALPAPE+ G YR PA VE+ Sbjct 1968 AEVRAQLGERLPAYMVPVAVVVLDALPLTVNGKLDKRALPAPEFKKAGGEYRGPATAVEE 2027 Query 1992 TVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGL 2051 T+A IFA VLGL+RV V+DSFF++GGDSL+AMRVIA +NT L+A+L VR L A + R L Sbjct 2028 TLADIFAGVLGLQRVSVEDSFFDVGGDSLSAMRVIAEVNTALDANLSVRTLFEAPTVRRL 2087 Query 2052 SQLLGRDARPTSD-----PRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPE 2106 Q RDA + P SVHG + T+V ASDLTLD+FIDA TL A LPGPS E Sbjct 2088 GQRAERDAGGADELEAGGPSFASVHGRDATQVFASDLTLDKFIDAATLGNAPALPGPSSE 2147 Query 2107 LRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDEDARRRLEKTFDSGDPELL 2165 +RTVLLTGATGFLGRYL L+ L +L+ VDG+LICLVRA SDE+AR+RLEKTFD+GDP+LL Sbjct 2148 VRTVLLTGATGFLGRYLALQWLEQLELVDGKLICLVRAGSDEEARQRLEKTFDTGDPKLL 2207 Query 2166 RHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA-FPYHELFGPN 2224 R+F+ELAAD LEVVAGDK +LGLD+P W+RLA+TVDLIVDSAA+VN PY ELFGPN Sbjct 2208 RYFQELAADHLEVVAGDKGAANLGLDEPTWQRLADTVDLIVDSAALVNGVLPYSELFGPN 2267 Query 2225 VAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYG 2284 VAGTAELIR+ALTTKLKP+ YVST+DVG I+P+AFTEDADIR ISP R VDG +A GYG Sbjct 2268 VAGTAELIRVALTTKLKPYAYVSTSDVGRQIDPAAFTEDADIREISPIRKVDGSYANGYG 2327 Query 2285 TSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPR 2344 SKWAGEVLLREA+DLC LPV+VFR MIL+DTSYAGQ N+SD TRMVLSL+ATGIAPR Sbjct 2328 NSKWAGEVLLREAHDLCGLPVSVFRSDMILSDTSYAGQFNLSDMFTRMVLSLVATGIAPR 2387 Query 2345 SFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDE 2404 SFY+ D+EGNRQR+HFD LPV FVAEA+ LGA+V + GF TYHVMNPHDDGIG+DE Sbjct 2388 SFYQLDAEGNRQRSHFDALPVEFVAEAVTTLGAQV----VEGFETYHVMNPHDDGIGIDE 2443 Query 2405 YVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTR 2464 YVDWLIEAGYPI RIDDF EWL+RFEA+L LP+RQR+HSVL ML +LQ +P Sbjct 2444 YVDWLIEAGYPIERIDDFGEWLRRFEAALRELPERQRKHSVLQMLQVPGYNQLQAPEPAT 2503 Query 2465 GCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 G APTDRFRAAV+ AK+G+D DIPHVS P I+ YVT+LQL+GLL Sbjct 2504 GSFAPTDRFRAAVQEAKIGADN---DIPHVSPPVIVKYVTDLQLVGLL 2548 Score = 742 bits (1915), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/571 (69%), Positives = 451/571 (79%), Gaps = 6/571 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R + SID LDG E RLDEWGNRAVLTAPA VSIP + A QVAR+PEA A+ S+ Sbjct 7 RRLLSIDLLDGGEHDRLDEWGNRAVLTAPATGAVSIPALFAKQVARVPEAPALTFEGRSL 66 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TY+ELDEA+NRLAH LA GA PGECVALL R A A+V+++AVLKTGAAYLPIDPA P Sbjct 67 TYQELDEAANRLAHLLADHGARPGECVALLLSRSAEAIVSILAVLKTGAAYLPIDPAVPA 126 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYIL 1637 R+ FMLGDA PVAAVTTA LR+RL G DL ++DV D A+A P + P PA ++AY++ Sbjct 127 ARMEFMLGDAAPVAAVTTAELRARLDGFDLLVVDVDDPAVADQPSSALPGPAPEDIAYMI 186 Query 1638 YTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGR 1697 YTSGTTG PKGV +TH+NVT+L LPA L A VWSQ HS FD S WEIWG LL GGR Sbjct 187 YTSGTTGTPKGVAVTHQNVTQLLKKLPADLPKAGVWSQWHSLVFDVSVWEIWGPLLHGGR 246 Query 1698 LVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVD 1757 LV+VPESVA SP++ H LL+AE V+VL QTP+AV ML GL++ AL+VAGEACP+ +VD Sbjct 247 LVVVPESVAGSPDELHALLIAEKVTVLCQTPSAVGMLSPDGLDATALIVAGEACPSEVVD 306 Query 1758 RWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVA 1817 RWAPGRVM+NAYGPTE T+ A++S+ L+ SG PPIG PV GAALFVLD WLRP P GV Sbjct 307 RWAPGRVMINAYGPTEGTVYASMSSALKAESGAPPIGSPVPGAALFVLDKWLRPAPEGVV 366 Query 1818 GELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDD 1877 GELYIAG GV GY RR GLTASRF+ACPFG G RMYRTGDLV W DGQL++LGR D+ Sbjct 367 GELYIAGRGVASGYVRRPGLTASRFIACPFGAPGTRMYRTGDLVRWGVDGQLQYLGRADE 426 Query 1878 QVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRA 1937 QVKIRGYRIELGE+ TALA L GV QAVVIAREDRPGDKRLVGY T G DPA +R Sbjct 427 QVKIRGYRIELGEIQTALAALDGVEQAVVIAREDRPGDKRLVGYIT----GTADPAEIRT 482 Query 1938 QLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEKTVAGI 1996 QL +RLPGY+VPAAVVV+DALPLTVNGKLD RALPAPEY TNG YRAP VE+T+ I Sbjct 483 QLGRRLPGYMVPAAVVVLDALPLTVNGKLDKRALPAPEYQKTNGEYRAPTTAVEETLTAI 542 Query 1997 FARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 543 YAQVLGVERVGVDDSFFDLGGDSILSMQVVA 573 Score = 93.2 bits (230), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 165/642 (26%), Positives = 255/642 (40%), Gaps = 97/642 (15%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAIS----RAYGWGAHDTVLQCAPLTSDISVEE 630 AY++ TSGTTG PK V ++H ++ + +A W Q L D+SV E Sbjct 183 AYMIYTSGTTGTPKGVAVTHQNVTQLLKKLPADLPKAGVWS------QWHSLVFDVSVWE 236 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 I+G G RLV S A +L AL+ + + T + P+AV L D +DA Sbjct 237 IWGPLLHGGRLVVVPESVAGSPDELHALL--IAEKVTVLCQTPSAVGML---SPDGLDAT 291 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMD 747 +++ GEA VD+W + G ++++YGPTE TV A+ + + Sbjct 292 A------LIVAGEACPSEVVDRW-----APGRVMINAYGPTEGTVYAS----MSSALKAE 336 Query 748 GALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYL---GIDGDGF-GTVT 792 +G P+ +F+ GE+ I G VA GY+ G+ F Sbjct 337 SGAPPIGSPVPGAALFVLDKWLRPAPEGVVGELYIAGRGVASGYVRRPGLTASRFIACPF 396 Query 793 AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVA 852 A G+R + TGD V +G + GR D VKI G R+++ E+ +A V Sbjct 397 GAPGTR--MYRTGDLVRWGVDGQLQYLGRADEQVKIRGYRIELGEIQTALAALDGVEQAV 454 Query 853 VELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNG 908 V G V + + E R+ +V VV + +P NG Sbjct 455 VIAREDRPGDKRLVGYITGTADPAEIRTQLGRRLPGYMVPAA-----VVVLDALPLTVNG 509 Query 909 KIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLI 967 K+D LP G A T L+ I+++ LG +G D S G S+ + Sbjct 510 KLDKRALPAPEYQKTNGEYRAPTTAVEETLTAIYAQVLGVERVGVDDSFFDLGGDSILSM 569 Query 968 RILPETRRYLGWRLSLLDLIGADTAANLADYAPT-PDAPTGEDRFRPLVAAQRPAAIPLS 1026 +++ R G D+ T A LA A D ++ P+VA P+ Sbjct 570 QVVARARA-AGVVCRPRDVFVEQTVARLARVAGVASDEDVVDEGIGPVVAT------PI- 621 Query 1027 FAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDG- 1085 + +L Q+ P +N + ++ + + + + ++ RH +LR DG Sbjct 622 -----MRWLQQVDGPTDQFNQTMVVQAPAGVTGDDVLVVLQSLLDRHATLRMRVDD-DGA 675 Query 1086 ------VPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR-TWL 1138 VP +EA A D L A AAR + A LR W Sbjct 676 GGWSMQVPEAGAVEAA----------ACLHTVDALSDASLVAARSQLNPAAGTMLRAVW- 724 Query 1139 FRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGR 1180 A+ L + HH+A DG S L DL+ A+A +G+ Sbjct 725 ---AESTAQLALMIHHLAVDGVSWRILLEDLNIAWAQHHSGQ 763 Score = 91.3 bits (225), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 129/448 (29%), Positives = 183/448 (41%), Gaps = 53/448 (11%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYG----WGAHDTVLQCAPLTSDISVEE 630 AY++ TSGTTG PK V ++H + + + W Q L D+SV E Sbjct 1674 AYVIYTSGTTGVPKGVAVTHHNATQLLEKLHADLPDPGVWA------QWHSLVFDVSVHE 1727 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 IFG G RLV S A DL AL LVA T++ + +L +G A+ Sbjct 1728 IFGALLHGGRLVVVPESVAGSPKDLHAL---LVAENVTVLSQTPSAVGMLSPEGLESTAL 1784 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF-LPIVCDQTTM 746 V+ GEA V++W + G ++++YGPTE TV A P+ D Sbjct 1785 --------VVAGEACPPEVVERW-----APGRVMINAYGPTEGTVYAAMSAPLNADAGAP 1831 Query 747 DG------ALLRLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF-GTVTAADG 796 G AL L + + P + GE+ I G VA GY G+ F A G Sbjct 1832 IGSPVPGAALFVLDKWLRPAPEGV-VGELYIAGRGVACGYARRSGLTASRFVACPFGAPG 1890 Query 797 SRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELH 856 SR + TGD V A+G + GR D VKI G R+++ E+ +A V AV Sbjct 1891 SR--MYRTGDLVRWGADGQLQYLGRVDEQVKIRGYRIELGEIQAALAGLDGVEQAAVIAR 1948 Query 857 SGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDS 912 G V + + E A R+ +V + VV + +P NGK+D Sbjct 1949 EDRPGDKRLVGYITGTADPAEVRAQLGERLPAYMVPVA-----VVVLDALPLTVNGKLDK 2003 Query 913 DNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILP 971 LP A G L+ I++ LG + + + S G SL +R++ Sbjct 2004 RALPAPEFKKAGGEYRGPATAVEETLADIFAGVLGLQRVSVEDSFFDVGGDSLSAMRVIA 2063 Query 972 ETRRYLGWRLSLLDLIGADTAANLADYA 999 E L LS+ L A T L A Sbjct 2064 EVNTALDANLSVRTLFEAPTVRRLGQRA 2091 >gi|41407518|ref|NP_960354.1| hypothetical protein MAP1420 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395871|gb|AAS03737.1| hypothetical protein MAP_1420 [Mycobacterium avium subsp. paratuberculosis K-10] Length=6384 Score = 1466 bits (3795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 864/1690 (52%), Positives = 1066/1690 (64%), Gaps = 117/1690 (6%) Query 474 WLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEI 519 +++ GA PG+ + + + I ++A +G Y + D A + Sbjct 3465 FMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIV 3524 Query 520 SVRTNAITEHGDGILVTVVDVA----ATQLAVVGHDELRKVVDERVTQVTHDALLATKTA 575 +V T A+ E G +TV+DVA ATQ A V D A Sbjct 3525 AVTTAALAERLHGFDLTVIDVADPAVATQPATA-----PPVPDP------------DDVA 3567 Query 576 YIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGA 635 +I+ TSGTTG PK V ++ ++A D + Q D SV EI+G Sbjct 3568 HIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWEIWGAL 3627 Query 636 ACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQI 695 G RLV + D LV T++ + LL DG +D + Sbjct 3628 LHGGRLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDG--LDGTA------L 3679 Query 696 VIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVAT----------FLPIVCDQTT 745 VIG E VD+W + G ++++ YGPTE T+ A F PI T Sbjct 3680 VIGAEPCPPELVDRW-----APGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTR 3734 Query 746 MDGALLRLG---RPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRR 799 A L RP+ P V GE+ + GD V GY G+ F + R Sbjct 3735 --AAFFVLDDWLRPVPPGVV----GELYLAGDGVGVGYWRRPGLTAARFLACPFGEPGTR 3788 Query 800 RAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGS 859 + TGD V +G + GR D VK+ G R+++ E+ ++ V V + Sbjct 3789 -MYRTGDLVCWGPDGQLRYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDN 3847 Query 860 LG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNL 915 G V + + + AA A R+ +V V V + ++P NGK+D+ L Sbjct 3848 PGDKRLVGYVTGSVAPAKARAALAERLPAYMVPAAV-----VVLDSLPMTVNGKLDTRAL 3902 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 P W G E+ L+ I++ LG + +G D S G SL +R++ Sbjct 3903 PAPDYWHTGGYRAPESPTEEI-LAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAIN 3961 Query 975 RYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWF 1034 L L + + A T A LA P PLVAA RP +PLSFAQ RLWF Sbjct 3962 SALDTDLPVRTVFEAPTIAQLA-----PRIAQSAGGLAPLVAAGRPDVVPLSFAQNRLWF 4016 Query 1035 LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEA 1094 +DQ Q P+P+YNMA ALRLRG LD ALGAA+ DVV RHESLRTVFP+ G PRQLV+ A Sbjct 4017 IDQSQGPSPLYNMAAALRLRGRLDAGALGAALGDVVARHESLRTVFPSHQGTPRQLVVPA 4076 Query 1095 RRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHH 1154 RA+ G D++DAT WPADRL A+++ RH+FDLA EIP+R LF +++DEHVLV V HH Sbjct 4077 ERAEFGWDVIDATDWPADRLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVVHH 4136 Query 1155 IAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAA 1214 IAADG S+ PL DLS AYASRCAG AP WA LPVQY DYTLWQR GDL+D DS I Sbjct 4137 IAADGMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLNDPDSRIGT 4196 Query 1215 QLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFM 1274 QLAYWE+ALAGMPERL LPT RPYP ADQRG S+ VDWPA +QQQVRRIAR+HNATSFM Sbjct 4197 QLAYWEDALAGMPERLALPTDRPYPAAADQRGDSVAVDWPAELQQQVRRIAREHNATSFM 4256 Query 1275 VVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 VV A LAVLLSK+ S DVAVGFPIAGR DPALD LVGFFVNTLVLR++L GDPSFAELL Sbjct 4257 VVQAALAVLLSKIGASSDVAVGFPIAGRRDPALDQLVGFFVNTLVLRIDLTGDPSFAELL 4316 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ-----DNPVGQLNLGD 1389 V+ARSLAA+E+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ D+P L LGD Sbjct 4317 ALVQARSLAAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGHDDPAAALALGD 4376 Query 1390 LQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKV 1449 L T +P+ ++ARMDLVFSLAER++ E AGIGG VE+RTDVF+A I+ LIERLR+V Sbjct 4377 LDVTSVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRTDVFDAATIETLIERLRRV 4436 Query 1450 LVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAE 1509 L A+ P R +S++D LD ERA L+E GN A+LT PA VS+P++ A QVAR+PE Sbjct 4437 LEAMTGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELFATQVARVPETV 4496 Query 1510 AVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAY 1569 A+ C D S+TYR+LDEASNRLAHRLA GAGPG+ VALLF R A AV A++AVLKTGAAY Sbjct 4497 ALVCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGAAY 4556 Query 1570 LPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMP 1628 LPIDP+ P RV FMLGDA P+AAVTTA L RLAG + ++DV D + P T P+P Sbjct 4557 LPIDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGIDTLPNTALPLP 4616 Query 1629 AAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEI 1688 +AY++YTSGTTG PKGV +TH NVT+L SL A L + VWSQCHS FD S WEI Sbjct 4617 DPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPSPGVWSQCHSLAFDVSVWEI 4676 Query 1689 WGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAG 1748 +GALL GGR+V++PE+VA SP+D H L+A HV+VLTQTP+AVAML QGLESV+LV+AG Sbjct 4677 FGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSAVAMLSPQGLESVSLVLAG 4736 Query 1749 EACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSW 1808 EACP +VD+WAPGRVM+N YGPTET++C +ISAPL GSG+PPIG PV GAALFVLD Sbjct 4737 EACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDES 4796 Query 1809 LRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQ 1868 LRPVP GV GELY+AG+GV GY R LTA+RFVACPFG GARMYRTGDLV WRADGQ Sbjct 4797 LRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGARMYRTGDLVRWRADGQ 4856 Query 1869 LEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPG 1928 L++LGR D+QVK+RGYRIELGE+ AL+ L GV QAVV+ARED PGDKRLVGY T G Sbjct 4857 LDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYIT----G 4912 Query 1929 AVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGP 1988 DPA RA+L +RLP Y+VPAAV+ +DA+PLT NGKLD RALPAP+Y YRAP P Sbjct 4913 TADPAEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDYA-AGEYRAPESP 4971 Query 1989 VEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASST 2048 E+ +AGI+A VLG++RVGVDDSFF+LGGDS++AMR+IAA+N LNADLPVR + A + Sbjct 4972 TEEILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAPTV 5031 Query 2049 RGLSQLLGRDA----------RPTSDPR---------LVSVHGDNPTEVHASDLTLDRFI 2089 L+ +G RPT P L + G +P A+ L LD + Sbjct 5032 AALAPRIGEGGSGLEPLTAGERPTVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPL 5091 Query 2090 DADTLATAVN 2099 D + L A+ Sbjct 5092 DTEALGAALG 5101 Score = 1426 bits (3691), Expect = 0.0, Method: Compositional matrix adjust. Identities = 811/1507 (54%), Positives = 999/1507 (67%), Gaps = 68/1507 (4%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V ++H ++ ++ G + QC L D+SV EIFG Sbjct 4622 AYLIYTSGTTGAPKGVAVTHHNVTQLLGSLD--AGLPSPGVWSQCHSLAFDVSVWEIFGA 4679 Query 635 AACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQ 694 G R+V L D L+AR T++ + +L G ++++ Sbjct 4680 LLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSAVAMLSPQG--LESV------S 4731 Query 695 IVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQ------TTMD 747 +V+ GEA VD+W + G +++ YGPTE ++ V+ P+ + +D Sbjct 4732 LVLAGEACPPEVVDQW-----APGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVD 4786 Query 748 GALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTA----ADGSRR 799 GA L + RP+ P V GE+ + G VA GYLG A A G+R Sbjct 4787 GAALFVLDESLRPVPPGVV----GELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGAR- 4841 Query 800 RAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGS 859 + TGD V A+G + GR D VK+ G R+++ E+ ++ V V + Sbjct 4842 -MYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDN 4900 Query 860 LG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNL 915 G V + + E A R+ +V V +G+ IP PNGK+D+ L Sbjct 4901 PGDKRLVGYITGTADPAEARARLGERLPAYMVPAAV-----LGLDAIPLTPNGKLDARAL 4955 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 P P ++A E+ L+ I++ LG + +G D S G S+ +R++ Sbjct 4956 P-APDYAAGEYRAPESPTEEI-LAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVN 5013 Query 975 RYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWF 1034 L L + + A T A LA P G PL A +RP +PLSFAQ RLWF Sbjct 5014 AALNADLPVRTVFEAPTVAALA-----PRIGEGGSGLEPLTAGERPTVVPLSFAQNRLWF 5068 Query 1035 LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEA 1094 LDQLQ P+PVYNMA ALRL G LDTEALGAA+ DVV RHESLRT+F A +G P+Q+V+ A Sbjct 5069 LDQLQGPSPVYNMAAALRLDGPLDTEALGAALGDVVARHESLRTLFAAPEGRPQQVVLPA 5128 Query 1095 RRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHH 1154 RAD G ++VDA+ W AD+L AI AR++FDLA +IPLR LFR+ DD HVLVAV HH Sbjct 5129 ERADFGWEVVDASGWSADQLDEAIGATARYTFDLAAQIPLRAELFRLRDDRHVLVAVVHH 5188 Query 1155 IAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAA 1214 IAADG S+ PL DL AAYA RC GR PDW PLPVQYVDYTLWQR G+L DS S IAA Sbjct 5189 IAADGMSITPLVRDLGAAYARRCDGRGPDWTPLPVQYVDYTLWQRAQFGELADSGSRIAA 5248 Query 1215 QLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFM 1274 QLAYW++ALAGMPERL LPT RPYP VADQRGA++ +DWPA +QQ++ +A +HNATSFM Sbjct 5249 QLAYWQDALAGMPERLALPTDRPYPLVADQRGATVEIDWPAELQQRIGDVAHRHNATSFM 5308 Query 1275 VVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 V+ L VLL+KL +PDVAVGFPIAGR DPALD+LVGFFVNTLVLRV+ AGDPSF ELL Sbjct 5309 VIQTALTVLLAKLGANPDVAVGFPIAGRRDPALDDLVGFFVNTLVLRVDAAGDPSFTELL 5368 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLG 1388 +VR RSL A+E+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ+ P L+LG Sbjct 5369 ARVRTRSLEAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGQDTGPAAGLSLG 5428 Query 1389 DLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRK 1448 D++ TP+P+DT TARMDL FS+ ER+ E EP GIGG VE+RTDVF+ +I LI RLR+ Sbjct 5429 DVEITPIPVDTHTARMDLTFSVGERWCESGEPGGIGGTVEFRTDVFDPDSIQTLIGRLRR 5488 Query 1449 VLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEA 1508 VL A+ P ++V S+D LD E ARLD GNRA LT P P S+P + A Q AR P+A Sbjct 5489 VLEAMTDDPTQSVWSVDLLDAGEHARLDTLGNRAALTGPPPRFDSLPTLFAEQAARTPDA 5548 Query 1509 EAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAA 1568 A+ CG MTYRELDEA+NR+AH L GAGPG VALLF R A A+VA++ VLK+GAA Sbjct 5549 VALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAIVAILGVLKSGAA 5608 Query 1569 YLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG-HDLPIIDVVD-ALAAYPGTPPP 1626 YLPIDPA P R+ FML DA P+ A++TA L RL G HD+P+IDV D A+ A P + P Sbjct 5609 YLPIDPALPGERIGFMLADAAPMVAISTAELAPRLHGQHDVPVIDVHDPAIEAAPSSALP 5668 Query 1627 MPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAW 1686 P A ++AY++YTSGTTG PKGV ++HRNVT+L + + L VWSQ HS FD S W Sbjct 5669 PPGADDIAYLIYTSGTTGVPKGVAVSHRNVTQLLTA-DSGLPREGVWSQWHSLAFDVSVW 5727 Query 1687 EIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVV 1746 EI+GALL GGRLV++P+SV SP+DFH LL+ E VSVL+QTP+A L +GLE + LVV Sbjct 5728 EIFGALLHGGRLVVIPDSVVRSPDDFHALLLDEQVSVLSQTPSAAGTLSPEGLEDLTLVV 5787 Query 1747 AGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS-GMPPIGVPVSGAALFVL 1805 AGEACPA LVDRWAPGR M+NAYGPTE T+ AISAPL+PGS PIG PV GA LFVL Sbjct 5788 AGEACPAELVDRWAPGRTMINAYGPTEATVYTAISAPLQPGSPAGVPIGFPVPGAGLFVL 5847 Query 1806 DSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRA 1865 D LRPVP GV GELY+ GAGV GYWRR GLTAS FVACPFG GARMYRTGDLVCWR+ Sbjct 5848 DESLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRS 5907 Query 1866 DGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEI 1925 DGQL++ GR D+QVK+RGYRIELGEV ALA L V QAVVIAREDRPG KRLVGY T Sbjct 5908 DGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYIT-- 5965 Query 1926 APGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAP 1985 G DPA +R LAQRLP Y+VPAAVV +DA+PLT NGKLD RALP PEY + YRAP Sbjct 5966 --GTADPAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEYTGSR-YRAP 6022 Query 1986 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHA 2045 + VE+TVAGI+A VLG+ERVGVDDSFF+LGGDS++AMRVI AIN +L +L VR L A Sbjct 6023 SNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVITAINASLGVELAVRTLFEA 6082 Query 2046 SSTRGLS 2052 + LS Sbjct 6083 PTVASLS 6089 Score = 1352 bits (3499), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/1212 (61%), Positives = 868/1212 (72%), Gaps = 31/1212 (2%) Query 867 QRTREGEQDAAAATRIRLVLVSLG------VSSFFVVGVPNIPRKPNGKIDSDNLPRLPQ 920 QRTR D A T+I V L + +V + P +GK+D LP P Sbjct 2791 QRTRHA-NDPRANTKIAQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALP-APD 2848 Query 921 WSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW 979 + A A + L I+ + LG +G D S G SL +R++ L Sbjct 2849 YQDADRYRAPSTAVEEILVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLIAAVNASLNT 2908 Query 980 RLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQ 1039 L + + A TAA LA + DR PLVA +RPA IPLSFAQ RLWF+DQ Q Sbjct 2909 DLGVRTVFEAPTAAELALRVGSE-----ADRPEPLVAGERPAVIPLSFAQTRLWFIDQFQ 2963 Query 1040 RPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADL 1099 P+P+YN+ VALRL G LD +AL AA+ADVV RHESLRTVF DG P+Q+VI A R Sbjct 2964 GPSPMYNITVALRLSGRLDADALRAALADVVARHESLRTVFATADGTPQQVVIPADRIGF 3023 Query 1100 GCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADG 1159 CD+VDA WP DRL+ A+ AAR++FDL+ E PL T LF DDEHVLV HHIAADG Sbjct 3024 ACDVVDARGWPEDRLREAMSAAARYTFDLSAESPLHTELFARGDDEHVLVVAVHHIAADG 3083 Query 1160 WSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYW 1219 WS+ P DL AYASRCAGR PDWAPLPVQY DYTLWQR LGD+DD S IAAQL +W Sbjct 3084 WSITPFARDLGVAYASRCAGRDPDWAPLPVQYADYTLWQRAHLGDVDDPGSRIAAQLDFW 3143 Query 1220 ENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAG 1279 +ALAG+PERL+LPT RPYP VAD RGA L VDWPA +QQQ+RR+AR+H+ATSFMVV A Sbjct 3144 TDALAGLPERLQLPTDRPYPAVADHRGARLAVDWPAELQQQLRRVAREHDATSFMVVQAA 3203 Query 1280 LAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVN---LAGDPSFAELLGQ 1336 A LL+K+S S DVAVGFPIAGR +P LD L+GFFVNTLVLRV+ L GDP+FAELL Q Sbjct 3204 FAALLAKVSASSDVAVGFPIAGRPEPVLDELIGFFVNTLVLRVDLNELGGDPTFAELLAQ 3263 Query 1337 VRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLGDL 1390 VR RSLAA+E+QDVPFE+LV+RL PTR+++HHPL+QV+L W++ P L LGDL Sbjct 3264 VRRRSLAAFEHQDVPFELLVERLNPTRSMSHHPLVQVLLGWENFPGEVTAPAAGLALGDL 3323 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 Q TPMP+ T TARMDL FSLAERF+E + AGI EYRTDVF+ + ++ LIERL+++L Sbjct 3324 QVTPMPLHTNTARMDLTFSLAERFTESGQRAGIAVTAEYRTDVFDGRTVEGLIERLQRLL 3383 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 AV A P+R +S++D LD E ARL++WGN AVL PA TPVS+P AAQ AR P+A A Sbjct 3384 TAVTADPQRRLSAVDLLDANEHARLEKWGNTAVLARPA-TPVSVPARFAAQAARTPDAVA 3442 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 + C SMTYRELDEA+NRLAH + GAGPGE VALLF R A A+VA++A LK+GAAYL Sbjct 3443 LTCDGRSMTYRELDEAANRLAHFMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYL 3502 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPA 1629 PIDPA P RV FML DA P+ AVTTA L RL G DL +IDV D A+A P T PP+P Sbjct 3503 PIDPALPAARVEFMLTDAAPIVAVTTAALAERLHGFDLTVIDVADPAVATQPATAPPVPD 3562 Query 1630 AVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL--PARLSAAQVWSQCHSYGFDASAWE 1687 ++A+I+YTSGTTG PKGV +T NV +LF L LS QVW+Q HSY FD S WE Sbjct 3563 PDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWE 3622 Query 1688 IWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVA 1747 IWGALL GGRLV+VPE+V+ SPN+FH LLV EHV+VLTQTP+AV +L T GL+ ALV+ Sbjct 3623 IWGALLHGGRLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDGLDGTALVIG 3682 Query 1748 GEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDS 1807 E CP LVDRWAPGR M+N YGPTETT+ A SAPL GSG PPIG PV+ AA FVLD Sbjct 3683 AEPCPPELVDRWAPGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTRAAFFVLDD 3742 Query 1808 WLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADG 1867 WLRPVP GV GELY+AG GVGVGYWRR GLTA+RF+ACPFG G RMYRTGDLVCW DG Sbjct 3743 WLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARFLACPFGEPGTRMYRTGDLVCWGPDG 3802 Query 1868 QLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAP 1927 QL +LGR D+QVK+RGYRIELGE+ AL+ L GV QAVV+ARED PGDKRLVGY T Sbjct 3803 QLRYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYVT---- 3858 Query 1928 GAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAG 1987 G+V PA RA LA+RLP Y+VPAAVVV+D+LP+TVNGKLD RALPAP+Y T GYRAP Sbjct 3859 GSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTVNGKLDTRALPAPDYWHTGGYRAPES 3918 Query 1988 PVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASS 2047 P E+ +AGI+A VLG++RVGVDDSFF+LGGDSL MR+I AIN+ L+ DLPVR + A + Sbjct 3919 PTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAINSALDTDLPVRTVFEAPT 3978 Query 2048 TRGLSQLLGRDA 2059 L+ + + A Sbjct 3979 IAQLAPRIAQSA 3990 Score = 817 bits (2111), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/1022 (49%), Positives = 619/1022 (61%), Gaps = 53/1022 (5%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A P++ Q +W +Q + + V +R+ G +D L + VVG ESLR F Sbjct 7 AYPVTRGQLDIWLAEQTGHLDVAWQLGVLVRIDGAIDPALLHQTMRHVVGEAESLRASFF 66 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRI 1141 DG Q +E DL + ++ P ++ R L + ++ LFR Sbjct 67 EADGQVFQKAVEYSDVDLTFYDLSGSSDPEREVREMTASIQRTPMPLTGPM-IKFALFRT 125 Query 1142 ADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREI 1201 E+ HHIA DG +A + ++A Y + +G+ P+P + + Q + Sbjct 126 GSAEYYWFTTCHHIAIDGMGIALVGRRIAAVYTALASGK-----PIPPAF--FGSLQDLV 178 Query 1202 LGDLD-DSDSPIAAQLAYW-----ENALAGMPERLRLPTARPYPPVADQRGASLVVDWPA 1255 G+L+ ++ + YW + AG P R PY P S V Sbjct 179 GGELEYEASAKFLEDKDYWLAHRPGDGTAGHPPRPADDGRDPYSP-------SPPVQLDE 231 Query 1256 SVQQQVRRIARQHNATSFMVVAAGLAVLLSKL--SGSPDVAVGFPIAGRSDPALDNLVGF 1313 SV V+ +++ V+ A A+L+ GS +V + FP++ R DP G Sbjct 232 SVIGSVKELSKALGIRRSSVLTAACALLVRGWCADGSDEVVLDFPVSRRVDPKSKTHPGM 291 Query 1314 FVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVD-------RLKPTRALT 1366 + L ++ +FA+ V RS A +Q P L R P R + Sbjct 292 LAGVVPLVLHAPAAATFADFCRHVDQRSREALRHQQFPTRTLDGEGDFSGPRQAPNRVVV 351 Query 1367 HHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGA 1426 + + L L+L D+ AT +F L + G G Sbjct 352 N--FVPARLT--------LSLADVPATATYTSFGPVGHFGLFFLGFGDQQFLSTVGTGQP 401 Query 1427 VEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTA 1486 + F+A L ERL+++L A+AA P R +SS+D L E A+L+ GN AVLT Sbjct 402 LAN----FDATD---LAERLQRILAAMAADPARLLSSLDVLRDPEHAQLEALGNTAVLTR 454 Query 1487 PAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVA 1546 VS+P++ A QVAR P+ A+ C S+TYR+LDEASNRLAH LAG GAGPG+ VA Sbjct 455 TPGPAVSVPELFATQVARAPQDVALVCEGRSLTYRQLDEASNRLAHLLAGLGAGPGQSVA 514 Query 1547 LLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGH 1606 LLF R A AV +++AVLKTGAAYLPIDPA P R+ FML DA PVAA++TA L RL GH Sbjct 515 LLFSRSAEAVASILAVLKTGAAYLPIDPAAPETRIGFMLADAKPVAALSTAELAGRLEGH 574 Query 1607 DLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPA 1665 + +IDV D + P T P+PAA +AY++YTSGTTG PKGV +THRNVT+L SL A Sbjct 575 GMTVIDVNDPRIQDRPATALPVPAADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDA 634 Query 1666 RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLT 1725 L A VWSQCHSY FD S WEI+GALL GGRLV+VPE V +P + H +LV E VSVLT Sbjct 635 GLPPAGVWSQCHSYAFDVSVWEIFGALLRGGRLVVVPEDVTRAPEELHDVLVNEQVSVLT 694 Query 1726 QTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLR 1785 QTP+AVAML QGLESV+LVV GEACPA +VDRW+PGRVM+NAYGPTETT+C AISAPL Sbjct 695 QTPSAVAMLSPQGLESVSLVVVGEACPAEVVDRWSPGRVMVNAYGPTETTMCVAISAPLA 754 Query 1786 PGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVAC 1845 PG G PPIGVPV GA LFVLD+WLRPVP GV GELY+ GAGV GYWRR GLTAS FVAC Sbjct 755 PGMGSPPIGVPVDGAGLFVLDAWLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVAC 814 Query 1846 PFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAV 1905 PFG GARMYRTGDLVCWR+DGQL++ GR D+QVK+RGYRIELGEV ALA L V QAV Sbjct 815 PFGAPGARMYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIELGEVQAALAALDDVDQAV 874 Query 1906 VIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGK 1965 VIAREDRPG KRLVGY T G DPA +R LAQRLP Y+VPAAVV +DA+PLT NGK Sbjct 875 VIAREDRPGGKRLVGYIT----GTADPAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGK 930 Query 1966 LDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRV 2025 LD RALP PEY + YRAP+ VE+TVAGI+A VLG+ERVGVDDSFF+LGGDS++A++V Sbjct 931 LDTRALPTPEYTGSR-YRAPSNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISALQV 989 Query 2026 IA 2027 +A Sbjct 990 VA 991 Score = 341 bits (874), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 309/911 (34%), Positives = 430/911 (48%), Gaps = 85/911 (9%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF-----PAVDGVPRQLVIEARRAD 1098 +Y + + L G LD + L AV VV RH L +F V +P +E R + Sbjct 1534 MYAVQLDFTLTGPLDADRLREAVRTVVHRHPHLAALFCDQYDEPVQIIPADPAVEWRYVE 1593 Query 1099 LGCDIVDAT-AWPADRLQRAIEEAARHSF-DLATEIPLRTWLFRIADDEHVLVAVAHHIA 1156 L D T A AD L + A R + DLA + RT L R D H V +HHI Sbjct 1594 L-----DGTGAADADDLIEQLCAAERAAVADLAGQPVFRTALVRTGGDRHRFVLTSHHIL 1648 Query 1157 ADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQL 1216 DGWS+ L ++ A Y + P Y + W E DLD AA+ Sbjct 1649 LDGWSLPILLREIFAGYYGQRL-------PAAGSYRAFLTWLAE--RDLD------AARR 1693 Query 1217 AYWENALAGMPE-RLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMV 1275 A W L+G L P R + R P + + +AR + T V Sbjct 1694 A-WGEVLSGFDTPTLVAPEGR----LGQGRRGFEKSCVPEQTTRALGELARSCHTTLSTV 1748 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDN---LVGFFVNTLVLRVNLAGDPSFAE 1332 + A AV+L+ L+G DV G P + +D+ +VG +NT+ +R + + A+ Sbjct 1749 LQAAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLLINTVPVRAEITATTTTAQ 1808 Query 1333 LLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQ-LNLGDLQ 1391 LL Q++ E+Q + + R H L + +++ P+ + LG Sbjct 1809 LLAQLQNSHNDTLEHQHLALNEI------HRVTGHDQLFDTLFVYENYPIDSGMTLG--- 1859 Query 1392 ATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLV 1451 A + I T R + L G E +G +E+ TDVF+ +I+ L++RL++VLV Sbjct 1860 ADGLAIAEFTNREYNHYPLTVEALPGPE---LGLHIEFDTDVFDTASIESLVQRLQRVLV 1916 Query 1452 AVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAV 1511 A++ P+R +SS+D LD ER + + A ++AP + A +A A+ Sbjct 1917 AMSTDPDRRLSSLDLLDRGERELVLSTMSGAGVSAPIGVAPQLLAAAVAADP---DAPAI 1973 Query 1512 CCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLP 1571 G ++YRELD+ S RLA +L G GP + ERCA VVA AV K G Y P Sbjct 1974 VDGARELSYRELDDWSTRLARKLIQHGVGPEHAAGVAIERCAELVVAWWAVTKVGGVYAP 2033 Query 1572 IDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPA-- 1629 ++ +P R+A +L D V V T G PI+ + + T P A Sbjct 2034 VNLDHPVERIASVL-DTVNAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTEPITDADR 2092 Query 1630 -----AVNLAYILYTSGTTGEPKGVGITHRNV------TRLFASLPARLSAAQVWSQCHS 1678 A + AY+++TSG+TG PKGV ++H + R L A V S Sbjct 2093 RSPLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPT-- 2150 Query 1679 YGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQG 1738 FDAS E+ A G L++ P V A LL + V TP ++ L Sbjct 2151 --FDASVGELLLAAGSGAALIVAPPQVYAG-EALTALLHNQRVGTAILTPTVISTLDRGR 2207 Query 1739 LESV-ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTI---CAAISA--PLRPGSGMPP 1792 L+ + LV GEAC LVD WAPGR M N YGP+ETTI CA ++A P+R Sbjct 2208 LDGLHTLVAVGEACLPELVDGWAPGRQMFNGYGPSETTIWVTCARLTAGHPVR------- 2260 Query 1793 IGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGA 1852 IG P+ G VLD WL+PVP GV GELY++G +G GY R LTA RFVA PFGG G Sbjct 2261 IGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGGPGE 2320 Query 1853 RMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDR 1912 RMYRTGDLV W +G L++LGR D+Q+K+RG RIELGE+ L V QA V ++ Sbjct 2321 RMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQDSA 2380 Query 1913 PGDKRLVGYAT 1923 G + LV Y T Sbjct 2381 AGSQ-LVAYVT 2390 Score = 108 bits (270), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 213/815 (27%), Positives = 326/815 (40%), Gaps = 142/815 (17%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A AY++ TSGTTG PK V ++H ++ ++ G QC D+SV E Sbjct 599 ADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLD--AGLPPAGVWSQCHSYAFDVSVWE 656 Query 631 IFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRS 690 IFG G RLV T L D LV + +++ + +L G ++++ Sbjct 657 IFGALLRGGRLVVVPEDVTRAPEELHDVLVNEQVSVLTQTPSAVAMLSPQG--LESV--- 711 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTT---- 745 +V+ GEA VD+W S G ++++YGPTE T+ VA P+ + Sbjct 712 ---SLVVVGEACPAEVVDRW-----SPGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIG 763 Query 746 --MDGALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF-GTVTAAD 795 +DGA L + RP+ P V GE+ + G VA GY G+ F A Sbjct 764 VPVDGAGLFVLDAWLRPVPPGVV----GELYVGGAGVACGYWRRGGLTASWFVACPFGAP 819 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAE----DPAVSDV 851 G+R + TGD V ++G + GR D VK+ G R+++ EV +A D AV Sbjct 820 GAR--MYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIELGEVQAALAALDDVDQAVVIA 877 Query 852 AVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID 911 + G V + + E A A R+ + +V V V + IP PNGK+D Sbjct 878 REDRPGGKRLVGYITGTADPAEVRTALAQRLPVYMVPAAV-----VALDAIPLTPNGKLD 932 Query 912 SDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRIL 970 + LP P+++ + A + ++ I++ LG +G D S G S+ ++++ Sbjct 933 TRALP-TPEYTGSRYR-APSNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISALQVV 990 Query 971 PETRRY-LGWR----------LSLLDLIGA-DTAANLADYAPTPDAPTGEDRFRPLVAAQ 1018 R L R L ++G+ D AA +AD P PT R+ L AA+ Sbjct 991 ARARAAGLTCRPRDVFVEQTVARLARVVGSGDRAAEVADEGVGPVPPTPIMRW--LQAAE 1048 Query 1019 RPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRT 1078 R F Q L +Q PA V VA+ L+ +D A+ LR Sbjct 1049 RAGGATDQFNQTVL-----VQAPAGVTETEVAIVLQALVDRHAM-----------LRLRV 1092 Query 1079 VFPAVDG----VPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 DG VP ++AR D + A AAR + A L Sbjct 1093 TDDGADGWSFEVPEAGSVQARDCLRSVDALSDEAL----------LAARARLNPAAGTML 1142 Query 1135 RT-WLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVD 1193 W+ L + HH+A D S L DL+ A+A AG+ + AP Sbjct 1143 AALWVEATGQ----LAVIIHHLAVDAVSWWILLEDLNIAWALHRAGQPVELAP---AGTS 1195 Query 1194 YTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYP-PVAD--------- 1243 + W R L D D + QL W+ + P A P P P D Sbjct 1196 FARWAR--LLDEHARDPEVVGQLDRWKTVTS-------TPAALPAPRPDVDTYASAGRLS 1246 Query 1244 -----QRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFP 1298 + A L+ + PA+ + I +++A GLA ++ G P +G Sbjct 1247 VELDAETTAMLLGEVPAAFHAGIHDI---------LLIAFGLA--WTEFLGEPGAPIGID 1295 Query 1299 IAGR-------SDPALDNLVGFFVNTLVLRVNLAG 1326 + G +D L VG+F + +++AG Sbjct 1296 VEGHGRHEELGADIDLSRTVGWFTAKYPVSLDVAG 1330 Score = 89.7 bits (221), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 95/309 (31%), Positives = 136/309 (45%), Gaps = 38/309 (12%) Query 569 LLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISV 628 L A TAY++ TSG+TG PK V +SH L + A +G GA VL A T D SV Sbjct 2096 LRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPTFDASV 2155 Query 629 EEIFGGAACGARL-VRSAAMKTGD-LAALVDDLVARETTIVDLPTAVWQLLCADGDAIDA 686 E+ A GA L V + G+ L AL+ + R T + PT + L D +D Sbjct 2156 GELLLAAGSGAALIVAPPQVYAGEALTALLHN--QRVGTAILTPTVISTL---DRGRLDG 2210 Query 687 IGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM 746 L +V GEA VD W + G + + YGP+E T+ T C + T Sbjct 2211 -----LHTLVAVGEACLPELVDGW-----APGRQMFNGYGPSETTIWVT-----CARLTA 2255 Query 747 DGALLRLGRPI-----------LPNTVFLAFGEVVIVGDLVADGYLG---IDGDGFGTVT 792 G +R+G PI L GE+ + G + GYLG + + F Sbjct 2256 -GHPVRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERF-VAN 2313 Query 793 AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVA 852 G R + TGD V EG + GR D +K+ G+R+++ E+ + P V+ A Sbjct 2314 PFGGPGERMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAA 2373 Query 853 VELHSGSLG 861 V + + G Sbjct 2374 VTVQDSAAG 2382 >gi|254823419|ref|ZP_05228420.1| linear gramicidin synthetase subunit D [Mycobacterium intracellulare ATCC 13950] Length=4386 Score = 1457 bits (3771), Expect = 0.0, Method: Compositional matrix adjust. Identities = 853/1604 (54%), Positives = 1033/1604 (65%), Gaps = 103/1604 (6%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEIS 520 L GA PG V+ + + + ++A G Y + D + Sbjct 808 LASAGAGPGRVVALLFSRSAEAVASILAVLKTGAAYLPIDPSSPDARIEFMLGDAKPVAA 867 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLA---TKTAYI 577 V T + E DG VT++DV D RV + AL A AY+ Sbjct 868 VTTADLAERLDGRGVTIIDVN----------------DPRVDTLPDTALPAPGPDHLAYL 911 Query 578 MPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAAC 637 + TSGTTG PK V I+H ++ ++ G A QC L D+SV EIFG Sbjct 912 IYTSGTTGVPKGVAITHRNVTQLLGSLD--AGLPAAGVWSQCHSLAFDVSVWEIFGALLR 969 Query 638 GARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVI 697 G RLV L D LVA++ +++ + +L +G +D++ +V+ Sbjct 970 GGRLVVVPEAVAASPHDLHDVLVAQQVSVLTQTPSAVAMLSREG--LDSV------SLVM 1021 Query 698 GGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFL--------PIVCDQTTMDGA 749 GEA VD+W + G ++++YGPTE T+ T P+ A Sbjct 1022 AGEACPAEVVDQW-----APGRVMVNAYGPTETTMCVTISAPLAAGTGPVPIGSPVPGAA 1076 Query 750 LLRLG---RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGSRRRAFAT 804 L L RP+ P V GE+ + G VA GY+G G A G+ R + T Sbjct 1077 LFVLDDALRPVPPGVV----GELYVAGSGVAAGYVGRPGLTASRFVACPFGGAGTRMYRT 1132 Query 805 GDRVTVDAEGFPVFS----GRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSL 860 GD V + G V GR D VKI G R+++ E+ +A V+ V Sbjct 1133 GDLVRWEPSGSGVGQLLCLGRADEQVKIRGYRIELGEIQSALAGFDGVAQAVVVAREDRP 1192 Query 861 G----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLP 916 G V + + + AA + R+ +V V V + IP PNGK+D+ LP Sbjct 1193 GDKRLVGYVTGSADPTQLRAALSERLPAFMVPAAV-----VTLDAIPLTPNGKLDARALP 1247 Query 917 RLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRR 975 P+++A ET L+ +++ LG +G D S G S+ +R++ Sbjct 1248 A-PEYTAGRYRAPETLTEEI-LAGVYAGVLGVERVGVDDSFFDLGGDSISAMRLVAAINA 1305 Query 976 YLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFL 1035 L L + + A T A LA P G PL AA+RPA IPLSFAQ RLWFL Sbjct 1306 SLDAGLPVRAVFEAPTIAQLA-----PRVGEGGSGLEPLTAAERPAVIPLSFAQNRLWFL 1360 Query 1036 DQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEAR 1095 DQLQ P+PVYNMA ALRL G LD +ALGAA+ DVV RHESLRTVF A +G+P+Q+VI A Sbjct 1361 DQLQGPSPVYNMAAALRLDGPLDADALGAALGDVVVRHESLRTVFVAPEGLPQQVVIPAG 1420 Query 1096 RADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHI 1155 +AD G ++VDA W AD+L AI AR++FDL+ +IPLR LFRI DD HVLVAV HHI Sbjct 1421 KADFGWEVVDAGTWSADQLDEAIGATARYTFDLSAQIPLRAELFRIRDDRHVLVAVVHHI 1480 Query 1156 AADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQ 1215 AADG S+ PL DL AYA+RC GR PDW+PL VQYVDYTLWQR GDLDD DS IAAQ Sbjct 1481 AADGMSLTPLVRDLGVAYAARCDGRGPDWSPLSVQYVDYTLWQRAQFGDLDDGDSRIAAQ 1540 Query 1216 LAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMV 1275 LAYWE ALAGMPERL LPT RPYP VADQRGA++ +DW A +QQ+V +AR+HNATSFMV Sbjct 1541 LAYWEEALAGMPERLPLPTDRPYPLVADQRGATVQIDWSAELQQRVADVARRHNATSFMV 1600 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRV---NLAGDPSFAE 1332 V L VLLSK+S S DVAVGFPIAGR DPALD LVGFFVNTLVLRV NL GDP+FAE Sbjct 1601 VQTALMVLLSKISASSDVAVGFPIAGRRDPALDELVGFFVNTLVLRVDLENLGGDPTFAE 1660 Query 1333 LLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLN 1386 LL QVR RSLAAYE+QDVPFEVLV+RL P R+L+HHPL+QVMLAWQ+ P L Sbjct 1661 LLSQVRHRSLAAYEHQDVPFEVLVERLNPARSLSHHPLVQVMLAWQNFAGQKGGPAAGLA 1720 Query 1387 LGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERL 1446 LGD+ TP+P+DTRTARMDL FS+ ER+S+ EPAGIGG VE+RTDVF+A +I LI RL Sbjct 1721 LGDVDVTPIPVDTRTARMDLTFSMGERWSDAGEPAGIGGTVEFRTDVFDADSIAALIGRL 1780 Query 1447 RKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIP 1506 ++VL+A+ A P + +S++D LD E ARLD GNRA LT PA SIP + AAQ AR P Sbjct 1781 QRVLLAMTADPAQALSAVDLLDDAEHARLDALGNRAALTGPATETDSIPALFAAQAARTP 1840 Query 1507 EAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTG 1566 + AV C SMTYRELDEASNRLAH LA GAGPG+ VALLF R A+VA++AVLKTG Sbjct 1841 DTAAVVCDGHSMTYRELDEASNRLAHLLAARGAGPGQAVALLFSRSTEAIVAILAVLKTG 1900 Query 1567 AAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPP 1625 AAYLPIDPA P R+ FML DA P+A +T+ GL RL GHD+ +I V D L P T Sbjct 1901 AAYLPIDPALPAERIGFMLSDAAPIATLTSPGLADRLEGHDVTVIAVDDPELEDRPATAL 1960 Query 1626 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASA 1685 P P +LAY++YTSGTTG PKGV +THRNVT+L AS + L VWSQ HS FD S Sbjct 1961 PAPGPDHLAYLIYTSGTTGVPKGVAVTHRNVTQLLASKDSGLPRTGVWSQWHSLAFDVSV 2020 Query 1686 WEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALV 1745 WEI+GALL GGRLV+VPESVA SP D H LLVAE VSVL+QTP+A L GLESVALV Sbjct 2021 WEIFGALLHGGRLVVVPESVARSPEDLHALLVAERVSVLSQTPSAAGALSPAGLESVALV 2080 Query 1746 VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGM---PPIGVPVSGAAL 1802 VAGEACPA LVDRWAPGRVM+NAYGPTE T+ AAISAPL+ G+G PIG PV A Sbjct 2081 VAGEACPAELVDRWAPGRVMINAYGPTEATVYAAISAPLQGGTGAVGPVPIGSPVPNGAS 2140 Query 1803 FVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVC 1862 FVLD WLRPVP GV GELY+AGAGV GYW+RA LTASRFVACPFG G+RMYRTGDLV Sbjct 2141 FVLDEWLRPVPPGVVGELYVAGAGVACGYWKRAALTASRFVACPFGAPGSRMYRTGDLVR 2200 Query 1863 WRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYA 1922 WRADGQL++LGR D+QVKIRGYRIELG+V AL+ +AGV QAVV+AREDRPGDKRLVGY Sbjct 2201 WRADGQLDYLGRADEQVKIRGYRIELGDVRAALSWVAGVEQAVVVAREDRPGDKRLVGYV 2260 Query 1923 TEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGY 1982 T G DPA +RA LA+RLPGY++PAAVVV+ ALPLT NGKLD RALPAPEY D + Y Sbjct 2261 T----GTADPAAVRAALAERLPGYMIPAAVVVMQALPLTPNGKLDTRALPAPEYSDADQY 2316 Query 1983 RAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 RAP VE+ +AGI+A+VLGLERVGVDDSFF+LGGDS+++M+V+ Sbjct 2317 RAPDNAVEEILAGIYAQVLGLERVGVDDSFFDLGGDSISSMQVV 2360 Score = 1400 bits (3624), Expect = 0.0, Method: Compositional matrix adjust. Identities = 801/1376 (59%), Positives = 956/1376 (70%), Gaps = 61/1376 (4%) Query 767 GEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRV----TVDAEGFPVFS 819 GE+ + G+ V GY G+ F + R + TGD V + EG + Sbjct 35 GELYLAGEGVGVGYWRRPGLTASRFMACPFGEPGTRM-YRTGDLVCWGRSGSGEGQLRYL 93 Query 820 GRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRTREGEQD 875 GR D VK+ G R+++ E+ ++ V V G V + + Sbjct 94 GRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDRPGDKRLVGYITGTAEPARAR 153 Query 876 AAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRA 935 AA A R+ +V V V + +P NGK+D+ LP P + A + Sbjct 154 AAVAERLPAYMVPAAV-----VVLDALPMTVNGKLDARALPA-PDYQGGNGYRAPSTAIE 207 Query 936 AGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAAN 994 L+ I++ LG +G D S G SL +R++ L L + + A T A Sbjct 208 EILAGIYAGVLGVERVGVDDSFFDLGGDSLSTMRLITAINTTLETELPVRVVFEAPTVAQ 267 Query 995 LADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLR 1054 LA P R PLVAA+RPA IPLSFAQ RLWF+DQ Q P+P+YNMA ALRLR Sbjct 268 LA-----PRIAESSGRLEPLVAAERPAIIPLSFAQNRLWFIDQFQGPSPLYNMAAALRLR 322 Query 1055 GYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRL 1114 G LD ALGAA+ADVV RHESLRT+FP+ +G PRQ V+ A RA+ G ++VDATAWPA RL Sbjct 323 GRLDAHALGAALADVVSRHESLRTLFPSHEGTPRQEVVPAERAEFGWEVVDATAWPASRL 382 Query 1115 QRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYA 1174 A++ RH+FDLA EIP+R LF I +DEH+LV HHIAADG S+ PL ADLS AY Sbjct 383 DDAVKAVTRHAFDLAAEIPIRARLFTITEDEHLLVIAVHHIAADGMSLTPLGADLSLAYT 442 Query 1175 SRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPT 1234 SR AGRAPDWA LPVQY+DYTLWQR+ LGDLDD DS I AQLAYWE ALAGMPERL LPT Sbjct 443 SRSAGRAPDWADLPVQYIDYTLWQRDQLGDLDDGDSRIGAQLAYWERALAGMPERLELPT 502 Query 1235 ARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVA 1294 RPYP VADQRG S+VVDWPA +QQQVRR+AR+HNATSFMVV A LAVLLSK+S SPDVA Sbjct 503 DRPYPAVADQRGDSVVVDWPAELQQQVRRVARKHNATSFMVVQAALAVLLSKVSASPDVA 562 Query 1295 VGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEV 1354 VGFPIAGR DPALD LVGFFVNTLVLRV+LAGDPSFAELL +V+A+SLAA+E+QDVPFEV Sbjct 563 VGFPIAGRRDPALDQLVGFFVNTLVLRVDLAGDPSFAELLDRVQAQSLAAFEHQDVPFEV 622 Query 1355 LVDRLKPTRALTHHPLIQVMLAWQ-----DNPVGQLNLGDLQATPMPIDTRTARMDLVFS 1409 LV+R+ PTR+LTHHPL+QVMLAWQ D+P L LGDL+ T +P++ ++ARMDLVFS Sbjct 623 LVERVNPTRSLTHHPLVQVMLAWQNFAGHDDPAAGLALGDLEVTSVPVEDQSARMDLVFS 682 Query 1410 LAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDG 1469 LAER++E E AGIGG VE+RTDVF+A I+ LI RL++VL A+ A P +SS+D LD Sbjct 683 LAERWTERGEAAGIGGRVEFRTDVFDATTIEALIGRLQRVLTAMTAEPAHPLSSVDLLDE 742 Query 1470 TERARLDEWGNRAVLTAPA-PTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASN 1528 E ARL E GN AVLT PA P SIP++ AAQ AR PE+ A+ CGD S+TYRELDEASN Sbjct 743 AEHARLKELGNHAVLTRPAGDAPASIPELFAAQAARAPESVALVCGDLSVTYRELDEASN 802 Query 1529 RLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDA 1588 RLAH LA GAGPG VALLF R A AV +++AVLKTGAAYLPIDP++P R+ FMLGDA Sbjct 803 RLAHCLASAGAGPGRVVALLFSRSAEAVASILAVLKTGAAYLPIDPSSPDARIEFMLGDA 862 Query 1589 VPVAAVTTAGLRSRLAGHDLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPK 1647 PVAAVTTA L RL G + IIDV D + P T P P +LAY++YTSGTTG PK Sbjct 863 KPVAAVTTADLAERLDGRGVTIIDVNDPRVDTLPDTALPAPGPDHLAYLIYTSGTTGVPK 922 Query 1648 GVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAA 1707 GV ITHRNVT+L SL A L AA VWSQCHS FD S WEI+GALL GGRLV+VPE+VAA Sbjct 923 GVAITHRNVTQLLGSLDAGLPAAGVWSQCHSLAFDVSVWEIFGALLRGGRLVVVPEAVAA 982 Query 1708 SPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLN 1767 SP+D H +LVA+ VSVLTQTP+AVAML +GL+SV+LV+AGEACPA +VD+WAPGRVM+N Sbjct 983 SPHDLHDVLVAQQVSVLTQTPSAVAMLSREGLDSVSLVMAGEACPAEVVDQWAPGRVMVN 1042 Query 1768 AYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGV 1827 AYGPTETT+C ISAPL G+G PIG PV GAALFVLD LRPVP GV GELY+AG+GV Sbjct 1043 AYGPTETTMCVTISAPLAAGTGPVPIGSPVPGAALFVLDDALRPVPPGVVGELYVAGSGV 1102 Query 1828 GVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD----GQLEFLGRTDDQVKIRG 1883 GY R GLTASRFVACPFGG+G RMYRTGDLV W GQL LGR D+QVKIRG Sbjct 1103 AAGYVGRPGLTASRFVACPFGGAGTRMYRTGDLVRWEPSGSGVGQLLCLGRADEQVKIRG 1162 Query 1884 YRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRL 1943 YRIELGE+ +ALA GV QAVV+AREDRPGDKRLVGY T G+ DP LRA L++RL Sbjct 1163 YRIELGEIQSALAGFDGVAQAVVVAREDRPGDKRLVGYVT----GSADPTQLRAALSERL 1218 Query 1944 PGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEKTVAGIFARVLG 2002 P ++VPAAVV +DA+PLT NGKLD RALPAPEY T G YRAP E+ +AG++A VLG Sbjct 1219 PAFMVPAAVVTLDAIPLTPNGKLDARALPAPEY--TAGRYRAPETLTEEILAGVYAGVLG 1276 Query 2003 LERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDA--- 2059 +ERVGVDDSFF+LGGDS++AMR++AAIN +L+A LPVRA+ A + L+ +G Sbjct 1277 VERVGVDDSFFDLGGDSISAMRLVAAINASLDAGLPVRAVFEAPTIAQLAPRVGEGGSGL 1336 Query 2060 -------RPTSDPR---------LVSVHGDNPTEVHASDLTLDRFIDADTLATAVN 2099 RP P L + G +P A+ L LD +DAD L A+ Sbjct 1337 EPLTAAERPAVIPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPLDADALGAALG 1392 Score = 855 bits (2210), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/1101 (49%), Positives = 668/1101 (61%), Gaps = 78/1101 (7%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEA-----RRAD 1098 +Y + + + G LD L AV VV RH +L F P Q++ R + Sbjct 2902 LYAGQLNISIAGPLDPNRLRDAVHTVVSRHPNLVARFCDRYDEPVQIIPAGPAPAWRYLE 2961 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L DA +RL A E A DLA + R L R A + + LV HHI D Sbjct 2962 LDGTDTDAI----ERLCAA--ERAAVCGDLAEQPAFRVALVRTASERYRLVLTNHHIVLD 3015 Query 1159 GWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAY 1218 GWS+ L ++ AAY + R P AP Y + W L D D + A A Sbjct 3016 GWSMPILLGEIFAAYYGQ---RLPAAAP----YRSFVSW----LADRD-----LDAARAA 3059 Query 1219 WENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAA 1278 W AG + L + + Q S + PA + Q V +AR + T V+ A Sbjct 3060 WGEVFAGF-DTPTLVGPQDRTELGRQSVESFAL--PADLTQAVADLARSCHTTVNTVLQA 3116 Query 1279 GLAVLLSKLSGSPDVAVGFPIAGRSDPA----LDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 A LL L+G DV G ++GR PA D +VG +NT+ +R N++ + A+LL Sbjct 3117 AYAQLLCGLTGQRDVVFGTTVSGR--PAEIAGADTMVGLLINTVPVRANISAATTTADLL 3174 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNL-GDLQAT 1393 Q++ ++Q + + R L + A+++ P+ L G+ + Sbjct 3175 DQLQGAYNHTLDHQHLALNEI------HRITGQDALFDTLFAYENYPIDASALSGNHELA 3228 Query 1394 PMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAV 1453 I +R + + L + G E + VEY TDVF+A I LIERLR+VL A+ Sbjct 3229 VTDISSRESTH---YPLTVQAQPGRE---MRLQVEYDTDVFDAARIATLIERLRRVLAAM 3282 Query 1454 AAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC 1513 A P R +SSID L+ E RLD WG+RA+LT P TP SIP++ AQ AR P A AV Sbjct 3283 TADPARRLSSIDLLEPAEHDRLDAWGDRAILTQPG-TPASIPELFTAQAARTPHAPAVTY 3341 Query 1514 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPID 1573 SMTYRELDE+SNRLAH L G GPGE VALLF + A A+ A++AVLKTGAAYLPID Sbjct 3342 KGRSMTYRELDESSNRLAHLLIDRGVGPGESVALLFGKSADAIAAILAVLKTGAAYLPID 3401 Query 1574 PANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVN 1632 PA P R+ FMLGD P+AA+T A L +L GH L +ID+ D A+A P T P PA + Sbjct 3402 PALPAARIEFMLGDTAPMAALTVAALADKLDGHHLMVIDIHDRAVARQPVTALPAPAPEH 3461 Query 1633 LAYILYTSGTTGEPKGVGITHRNVTRLF--ASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 +A+I+YTSGTTG PKGV ++H NVTRLF ++ LSA QVW+Q HSY FD S WEIWG Sbjct 3462 VAHIIYTSGTTGVPKGVAVSHHNVTRLFDAQAVGVELSADQVWTQFHSYAFDFSVWEIWG 3521 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 ALL GGRLV+VP+SVA SP DFH LLVAE V+VL+QTP+AV ML QGL++ ALV+ E Sbjct 3522 ALLHGGRLVVVPDSVARSPMDFHALLVAEKVTVLSQTPSAVRMLSPQGLDAAALVIGAEP 3581 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CP LVDRWAPGRVM+N YGPTE TI ++ S PL GSG PPIG PV GA LFVLD WLR Sbjct 3582 CPPELVDRWAPGRVMVNVYGPTEATIFSSTSTPLSAGSGAPPIGSPVPGAGLFVLDGWLR 3641 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 PVPAGV GELY+AG GVG GYW+R+GLTASRFVACPFG G+RMYRTGDLV W DGQL+ Sbjct 3642 PVPAGVVGELYVAGRGVGYGYWKRSGLTASRFVACPFGEPGSRMYRTGDLVRWGTDGQLQ 3701 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 +LGR D+QVKIRGYRIE+GEV +ALA L GV QAVV+AREDRPGDKRLVGY T G Sbjct 3702 YLGRADEQVKIRGYRIEVGEVRSALAALDGVDQAVVVAREDRPGDKRLVGYIT----GPA 3757 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DPAG RA+LA+RLP Y+VP AVV +DALP+TVNGKLD RALPAPEY GYR+P P E Sbjct 3758 DPAGARAELAERLPAYMVPVAVVALDALPMTVNGKLDTRALPAPEY-SAAGYRSPTTPTE 3816 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 + +AGI+A VLG+ERVGVDDSFF+LGGDS++AMRVIAAIN+ ++ +PVR + A + Sbjct 3817 EILAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVIAAINSAMDTGVPVRVIFEAPTVAQ 3876 Query 2051 LSQLLGRD----------ARPTSDPR---------LVSVHGDNPTEVHASDLTLDRFIDA 2091 L+ + D ARP P L + G +P A+ L + +DA Sbjct 3877 LAPRICEDTGRLDPLVAGARPAVIPLSFAQSRLWFLDQLQGPSPVYNMAAALRMHGRLDA 3936 Query 2092 DTLATAV-NLPGPSPELRTVL 2111 L A+ ++ LRTV Sbjct 3937 HALGAALADVVARHESLRTVF 3957 Score = 763 bits (1969), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/1074 (46%), Positives = 623/1074 (59%), Gaps = 94/1074 (8%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEIS 520 L+ RG PG+ + + I ++A G Y + DTA + Sbjct 3362 LIDRGVGPGESVALLFGKSADAIAAILAVLKTGAAYLPIDPALPAARIEFMLGDTAPMAA 3421 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 + A+ + DG + V+D+ HD R V + VT + A A+I+ T Sbjct 3422 LTVAALADKLDGHHLMVIDI---------HD--RAVARQPVTALPAPA--PEHVAHIIYT 3468 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V +SH ++ DA + A Q D SV EI+G G R Sbjct 3469 SGTTGVPKGVAVSHHNVTRLFDAQAVGVELSADQVWTQFHSYAFDFSVWEIWGALLHGGR 3528 Query 641 LV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVI 697 LV S A D AL LVA + T++ + ++L G +DA +VI Sbjct 3529 LVVVPDSVARSPMDFHAL---LVAEKVTVLSQTPSAVRMLSPQG--LDAAA------LVI 3577 Query 698 GGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVA-TFLPIVCDQT------------ 744 G E VD+W + G +++ YGPTEAT+ + T P+ Sbjct 3578 GAEPCPPELVDRW-----APGRVMVNVYGPTEATIFSSTSTPLSAGSGAPPIGSPVPGAG 3632 Query 745 --TMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSR--RR 800 +DG L RP+ V GE+ + G V GY G A R Sbjct 3633 LFVLDGWL----RPVPAGVV----GELYVAGRGVGYGYWKRSGLTASRFVACPFGEPGSR 3684 Query 801 AFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSL 860 + TGD V +G + GR D VKI G R+++ EV +A V V Sbjct 3685 MYRTGDLVRWGTDGQLQYLGRADEQVKIRGYRIEVGEVRSALAALDGVDQAVVVAREDRP 3744 Query 861 G----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLP 916 G V + + A A R+ +V + V V + +P NGK+D+ LP Sbjct 3745 GDKRLVGYITGPADPAGARAELAERLPAYMVPVAV-----VALDALPMTVNGKLDTRALP 3799 Query 917 RLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRR 975 P++SAAG + T L+ I++ LG +G D S G S+ +R++ Sbjct 3800 A-PEYSAAGYRSPTTPTEEI-LAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVIAAINS 3857 Query 976 YLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFL 1035 + + + + A T A LA P R PLVA RPA IPLSFAQ RLWFL Sbjct 3858 AMDTGVPVRVIFEAPTVAQLA-----PRICEDTGRLDPLVAGARPAVIPLSFAQSRLWFL 3912 Query 1036 DQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEAR 1095 DQLQ P+PVYNMA ALR+ G LD ALGAA+ADVV RHESLRTVF A G P+Q+V+ A Sbjct 3913 DQLQGPSPVYNMAAALRMHGRLDAHALGAALADVVARHESLRTVFAAPQGTPQQVVLPAE 3972 Query 1096 RADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHI 1155 RADL +VDA W A RL+ AI+ AA +FDLAT+IPLR LFR+A+DEHVLVAV HHI Sbjct 3973 RADLSWRMVDARGWSAGRLREAIDIAAAETFDLATQIPLRASLFRVAEDEHVLVAVVHHI 4032 Query 1156 AADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQ 1215 AADGWS+ PL DL AYASR AGRAPDW PLPVQYVDYTLWQR+ G+L DS S IA Q Sbjct 4033 AADGWSLRPLVRDLGMAYASRSAGRAPDWEPLPVQYVDYTLWQRDQFGELADSGSRIAEQ 4092 Query 1216 LAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMV 1275 LAYW+ ALAGMPERL+LPT RPYP +ADQRGA++ VDWPA +QQQV +AR++N+TSFMV Sbjct 4093 LAYWQEALAGMPERLQLPTDRPYPQIADQRGAAVEVDWPADLQQQVAGLAREYNSTSFMV 4152 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLG 1335 V A LAVLLSK+S S DVAVGFPIAGR DPALD LVGFFVNTLVLRV+LAGDPSF +LL Sbjct 4153 VQAALAVLLSKISASTDVAVGFPIAGRRDPALDELVGFFVNTLVLRVDLAGDPSFTDLLA 4212 Query 1336 QVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLGD 1389 +VRARSL A+E+QDVPFEVLV+R+ P R+L+HHPL+QVMLAWQ+ +P L LGD Sbjct 4213 RVRARSLEAFEHQDVPFEVLVERVNPARSLSHHPLVQVMLAWQNFAGQDGDPGAGLALGD 4272 Query 1390 LQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKV 1449 ++ T +P+DT+ ARMDLVFSLAER+++G EPAGIGG VE+RTDVF+A +I LI RL +V Sbjct 4273 VRVTSIPLDTQVARMDLVFSLAERWTDGDEPAGIGGRVEFRTDVFDADSIRALIRRLERV 4332 Query 1450 LVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVA 1503 L A+ A P R +SS+D LD E ARLD GNRAVLTAPA SIP + AAQ A Sbjct 4333 LTAMTADPTRPMSSVDLLDAAEHARLDALGNRAVLTAPATEAGSIPALFAAQAA 4386 Score = 359 bits (921), Expect = 5e-96, Method: Compositional matrix adjust. Identities = 186/273 (69%), Positives = 218/273 (80%), Gaps = 8/273 (2%) Query 1784 LRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFV 1843 ++ GSG PPIG PV+ AA FVLD WLRPVPAGV GELY+AG GVGVGYWRR GLTASRF+ Sbjct 1 MQAGSGFPPIGSPVTRAAFFVLDEWLRPVPAGVVGELYLAGEGVGVGYWRRPGLTASRFM 60 Query 1844 ACPFGGSGARMYRTGDLVCW----RADGQLEFLGRTDDQVKIRGYRIELGEVATALAELA 1899 ACPFG G RMYRTGDLVCW +GQL +LGR D+QVK+RGYRIELGE+ AL+ L Sbjct 61 ACPFGEPGTRMYRTGDLVCWGRSGSGEGQLRYLGRADEQVKVRGYRIELGEIQAALSALD 120 Query 1900 GVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALP 1959 GV QAVV+AREDRPGDKRLVGY T G +PA RA +A+RLP Y+VPAAVVV+DALP Sbjct 121 GVEQAVVVAREDRPGDKRLVGYIT----GTAEPARARAAVAERLPAYMVPAAVVVLDALP 176 Query 1960 LTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDS 2019 +TVNGKLD RALPAP+Y NGYRAP+ +E+ +AGI+A VLG+ERVGVDDSFF+LGGDS Sbjct 177 MTVNGKLDARALPAPDYQGGNGYRAPSTAIEEILAGIYAGVLGVERVGVDDSFFDLGGDS 236 Query 2020 LAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 L+ MR+I AINTTL +LPVR + A + L+ Sbjct 237 LSTMRLITAINTTLETELPVRVVFEAPTVAQLA 269 Score = 103 bits (257), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 221/829 (27%), Positives = 310/829 (38%), Gaps = 156/829 (18%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC--------------GYSVCDTADEIS 520 L RGA PG + + + I ++A G G+ + D A + Sbjct 1868 LAARGAGPGQAVALLFSRSTEAIVAILAVLKTGAAYLPIDPALPAERIGFMLSDAAPIAT 1927 Query 521 VRTNAITEHGDGILVTVV--------DVAATQLAVVGHDELRKVVDERVTQVTHDALLAT 572 + + + + +G VTV+ D AT L G D L Sbjct 1928 LTSPGLADRLEGHDVTVIAVDDPELEDRPATALPAPGPDHL------------------- 1968 Query 573 KTAYIMPTSGTTGQPKLVRISHGS----LAVFCDAISRAYGWGAHDTVLQCAPLTSDISV 628 AY++ TSGTTG PK V ++H + LA + R W Q L D+SV Sbjct 1969 --AYLIYTSGTTGVPKGVAVTHRNVTQLLASKDSGLPRTGVWS------QWHSLAFDVSV 2020 Query 629 EEIFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAID 685 EIFG G RLV S A DL AL+ + R + + P+A L A +++ Sbjct 2021 WEIFGALLHGGRLVVVPESVARSPEDLHALL--VAERVSVLSQTPSAAGALSPAGLESV- 2077 Query 686 AIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFL-------- 737 +V+ GEA VD+W + G ++++YGPTEATV A Sbjct 2078 --------ALVVAGEACPAELVDRW-----APGRVMINAYGPTEATVYAAISAPLQGGTG 2124 Query 738 ---PIVCDQTTMDGALLRLG---RPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF 788 P+ +GA L RP+ P V GE+ + G VA GY + F Sbjct 2125 AVGPVPIGSPVPNGASFVLDEWLRPVPPGVV----GELYVAGAGVACGYWKRAALTASRF 2180 Query 789 -GTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPA 847 A GSR + TGD V A+G + GR D VKI G R+++ +V ++ Sbjct 2181 VACPFGAPGSRM--YRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGDVRAALSWVAG 2238 Query 848 VSDVAVELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIP 903 V V G V + + AA A R+ ++ V V + +P Sbjct 2239 VEQAVVVAREDRPGDKRLVGYVTGTADPAAVRAALAERLPGYMIPAAV-----VVMQALP 2293 Query 904 RKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIG 962 PNGK+D+ LP P++S A A L+ I+++ LG +G D S G Sbjct 2294 LTPNGKLDTRALPA-PEYSDADQYRAPDNAVEEILAGIYAQVLGLERVGVDDSFFDLGGD 2352 Query 963 SLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAA 1022 S+ ++++ R G D+ T A LA A DA D VAA P Sbjct 2353 SISSMQVVTRARAA-GLVCKTRDIFVEQTVARLARVAEVVDADAVLDEGVGPVAAT-PII 2410 Query 1023 IPLSFAQRRLWFLDQL------QRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESL 1076 L + +DQ Q PA V V L+ LD RH L Sbjct 2411 RWLQDVESVGGQVDQFNQAMLVQAPAGVTEADVVTMLQALLD-------------RHPML 2457 Query 1077 RTVFPAVDGVPRQ-------LVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLA 1129 R VDG Q V EA D D + D L A AR + A Sbjct 2458 RL---RVDGSGVQGSGDWSLTVPEAGSVD-AADCLHVV----DELSDAAVTEARSRLNPA 2509 Query 1130 TEIPLRT-WLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLP 1188 + L W A LV + HH+A DG S L DL+ A+A +GR + LP Sbjct 2510 AGVMLSALW----AGATGQLVVIVHHLAVDGVSWRILLQDLNIAWAQHHSGRPVE---LP 2562 Query 1189 VQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARP 1237 + W + D + Q W A P LP RP Sbjct 2563 AAGTSFARWSLRLAQHAHRPD--VVDQAERWTEVAATPPA---LPAVRP 2606 >gi|254775508|ref|ZP_05217024.1| linear gramicidin synthetase subunit D [Mycobacterium avium subsp. avium ATCC 25291] Length=4751 Score = 1453 bits (3761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 855/1686 (51%), Positives = 1061/1686 (63%), Gaps = 109/1686 (6%) Query 474 WLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEI 519 +++ GA PG+ + + + I ++A +G Y + D A + Sbjct 2550 FMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIV 2609 Query 520 SVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMP 579 +V T A+ E G +TV+DVA + AV V + A+I+ Sbjct 2610 AVTTAALAERLHGFDLTVIDVADS--AVATQPATAPPVPD-----------PDDVAHIIY 2656 Query 580 TSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGA 639 TSGTTG PK V ++ ++A D + Q D SV EI+G G Sbjct 2657 TSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGG 2716 Query 640 RLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGG 699 RLV + D LV T++ + LL DG +D +VIG Sbjct 2717 RLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDG--LDGTA------LVIGA 2768 Query 700 EAIRCSAVDKWLESAASQGISLLSSYGPTEATVVAT----------FLPIVCDQTTMDGA 749 E VD+W + G ++++ YGPTE T+ A F PI T A Sbjct 2769 EPCPPELVDRW-----APGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTR--AA 2821 Query 750 LLRLG---RPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFA 803 L RP+ P V GE+ + GD V GY G+ F + R + Sbjct 2822 FFVLDDWLRPVPPGVV----GELYLAGDGVGVGYWRRPGLTAARFLACPFGEPGTR-MYR 2876 Query 804 TGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG-- 861 TGD V A+G + GR D VK+ G R+++ E+ ++ V V + G Sbjct 2877 TGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDK 2936 Query 862 --VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLP 919 V + + + AA A R+ +V V V + ++P NGK+D+ LP P Sbjct 2937 RLVGYVTGSVAPAKARAALAERLPAYMVPAAV-----VVLDSLPMTVNGKLDTRALP-AP 2990 Query 920 QWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLG 978 + G A L+ I++ LG + +G D S G SL +R++ L Sbjct 2991 DYRHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAINSALD 3050 Query 979 WRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQL 1038 L + + A T A LA P PLVAA+RP +PLSFAQ RLWF+DQ Sbjct 3051 TDLPVRTVFEAPTIAQLA-----PRIAQSAGGLAPLVAAERPDVVPLSFAQNRLWFIDQF 3105 Query 1039 QRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRAD 1098 Q P+P+YNMA ALRLRG LD ALGAA+ DVV RHESLRTVFP+ G PRQLV+ A RA+ Sbjct 3106 QGPSPLYNMAAALRLRGRLDAGALGAALGDVVARHESLRTVFPSHQGTPRQLVVPAERAE 3165 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 G D++DAT WPADRL A+++ RH+FDLA EIP+R LF +++DEHVLV V HHIAAD Sbjct 3166 FGWDVIDATDWPADRLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVVHHIAAD 3225 Query 1159 GWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAY 1218 G S+ PL DLS AYASRCAG AP WA LPVQY DYTLWQR GDLDD DS I QL Y Sbjct 3226 GMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLDDPDSRIGTQLTY 3285 Query 1219 WENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAA 1278 W++ALAGMPERL LPT RPYP VADQRG S+ VDWPA +QQQVRR+AR+HNATSFMVV A Sbjct 3286 WQDALAGMPERLALPTDRPYPAVADQRGDSVAVDWPAELQQQVRRVAREHNATSFMVVQA 3345 Query 1279 GLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVR 1338 LAVLLSK+ S DVAVGFPIAGR DPALD LVGFFVNTLVLR++L GDPSFAELL +V+ Sbjct 3346 ALAVLLSKIGASSDVAVGFPIAGRRDPALDRLVGFFVNTLVLRIDLTGDPSFAELLARVQ 3405 Query 1339 ARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ-----DNPVGQLNLGDLQAT 1393 ARSLAA+E+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ D+P L LGDL T Sbjct 3406 ARSLAAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGHDDPAAALALGDLDVT 3465 Query 1394 PMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAV 1453 +P+ ++ARMDLVFSLAER++ E AGIGG VE+R DVF+A I+ LIERLR+VL A+ Sbjct 3466 SVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRIDVFDAATIETLIERLRRVLEAM 3525 Query 1454 AAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC 1513 P R +S++D LD ERA L+E GN A+LT PA VS+P++ A QVAR+ E A+ C Sbjct 3526 TGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPARGRVSVPELFATQVARVSETVALVC 3585 Query 1514 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPID 1573 D S+TYR+LDEASNRLAHRLA GAGPG+ VALLF R A AV A++AVLKTGAAYLPID Sbjct 3586 DDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGAAYLPID 3645 Query 1574 PANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVN 1632 P+ P RV FMLGDA P+AAVTT RLAG + ++DV D + P T P+P Sbjct 3646 PSAPQTRVEFMLGDAEPIAAVTTTEPAQRLAGRPVTVVDVDDPGIDTLPDTALPLPDPDG 3705 Query 1633 LAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGAL 1692 +AY++YTSGTTG PKGV +TH NVT+L SL A L + VWSQCHS FD S WEI+GAL Sbjct 3706 IAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPSPGVWSQCHSLAFDVSVWEIFGAL 3765 Query 1693 LGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACP 1752 L GGR+V++P +V SP+D H L+A HV+VLTQTP+AVAML QGLESV+LV+AGEACP Sbjct 3766 LRGGRVVVMPGAVTRSPHDLHDALIARHVTVLTQTPSAVAMLSPQGLESVSLVLAGEACP 3825 Query 1753 AALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPV 1812 +VD+WAPGRVM+N YGPTET++C +ISAPL GSG+PPIG PV GAALFVLD LRPV Sbjct 3826 PEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDESLRPV 3885 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELY+AG+GV GY R LTA+RFVACPFG GARMYRTGDLV WRADGQL++L Sbjct 3886 PPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGARMYRTGDLVRWRADGQLDYL 3945 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVK+RGYRIELGE+ AL+ L GV QAVV+ARED PGDKRLVGY T G DP Sbjct 3946 GRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYIT----GTADP 4001 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKT 1992 A RA+L +RLP Y+VPAAV+ IDA+PLT NGKLD RALPAP+Y YRAP P E+ Sbjct 4002 AEARARLGERLPAYMVPAAVLGIDAIPLTPNGKLDARALPAPDYA-AGEYRAPESPTEEI 4060 Query 1993 VAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 +AGI+A VLG++RVGVDDSFF+LGGDS++AMR+IAA+N LNADLPVR + A + L+ Sbjct 4061 LAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAPTVAALA 4120 Query 2053 QLLGRDA----------RPTSDPR---------LVSVHGDNPTEVHASDLTLDRFIDADT 2093 +G RP P L + G +P A+ L LD +D + Sbjct 4121 PRIGEGGSGLEPLTAGERPAVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPLDTEA 4180 Query 2094 LATAVN 2099 L A+ Sbjct 4181 LGAALG 4186 Score = 1349 bits (3491), Expect = 0.0, Method: Compositional matrix adjust. Identities = 720/1177 (62%), Positives = 857/1177 (73%), Gaps = 24/1177 (2%) Query 896 VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDS 954 +V + P +GK+D LP P A A + L I+ + LG +G D Sbjct 1910 IVALDEFPMTTSGKLDRKALP-APDDQDADRYRAPSTAVEEILVGIYGQVLGLERVGVDD 1968 Query 955 SLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPL 1014 S G SL +R++ L L + + A TAA LA + DR PL Sbjct 1969 SFFDLGGDSLSAMRLIAAVNASLNTDLGVRTVFEAPTAAELALRVGSE-----ADRPEPL 2023 Query 1015 VAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHE 1074 VA +RPA IPLSFAQ RLWF+DQ Q P+P+YN+ VALRL G LD +AL AA+ADVV RHE Sbjct 2024 VAGERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLSGRLDADALRAALADVVARHE 2083 Query 1075 SLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 SLRTVF DG P+Q+VI A R CD+V+A WP DRL+ A+ AAR++FDL+ E PL Sbjct 2084 SLRTVFATADGTPQQVVIPADRIGFACDVVEARGWPEDRLREAMSAAARYTFDLSAESPL 2143 Query 1135 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDY 1194 T LF DDEHVLV HHIAADGWS+ P DL AYASRCAGR PDWAPLPVQY DY Sbjct 2144 HTELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASRCAGRDPDWAPLPVQYADY 2203 Query 1195 TLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP 1254 TLWQR LGD+DD S IAAQL +W +ALAG+PERL+LPT RPYP VAD RGA L VDWP Sbjct 2204 TLWQRAHLGDVDDPGSRIAAQLEFWADALAGLPERLQLPTDRPYPAVADHRGARLAVDWP 2263 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFF 1314 A +QQQ+RR+AR+HNATSFMVV A A LL+K+S S DVAVGFPIAGR +P LD L+GFF Sbjct 2264 AELQQQLRRVAREHNATSFMVVQAAFAALLAKVSASSDVAVGFPIAGRPEPVLDELIGFF 2323 Query 1315 VNTLVLRVN---LAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 VNTLVLRV+ L GDP+FAELL QVR RSLAA+E+QDVPFE+LV+RL PTR+++HHPL+ Sbjct 2324 VNTLVLRVDLNELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSMSHHPLV 2383 Query 1372 QVMLAWQD------NPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGG 1425 QV+L W++ P L LGDLQ TPMP+ T TARMDL FSLAERF+E + AGI Sbjct 2384 QVLLGWENFPGEVTAPAAGLALGDLQVTPMPLHTNTARMDLTFSLAERFTESGQRAGIAV 2443 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 EYRTDVF+ + ++ LIERL+++L AV A P+R +S++D LD E ARL++WGN AVL Sbjct 2444 TAEYRTDVFDGRTVEGLIERLQRLLTAVTADPQRRLSAVDLLDANEHARLEKWGNTAVLA 2503 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 PA TPVS+P AAQ AR P+A A+ C S+TYRELDEA+NRLAH + GAGPGE V Sbjct 2504 RPA-TPVSVPARFAAQAARTPDAVALTCDGRSVTYRELDEAANRLAHFMIHHGAGPGERV 2562 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+VA++A LK+GAAYLPIDPA P RV FML DA P+ AVTTA L RL G Sbjct 2563 ALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLHG 2622 Query 1606 HDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL- 1663 DL +IDV D A+A P T PP+P ++A+I+YTSGTTG PKGV +T NV +LF L Sbjct 2623 FDLTVIDVADSAVATQPATAPPVPDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLR 2682 Query 1664 -PARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 LS QVW+Q HSY FD S WEIWGALL GGRLV+VPE+V+ SPN+FH LLV EHV+ Sbjct 2683 IGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDLLVREHVT 2742 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VLTQTP+AV +L T GL+ ALV+ E CP LVDRWAPGR M+N YGPTETT+ A SA Sbjct 2743 VLTQTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRWAPGRTMVNVYGPTETTMWACKSA 2802 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PL GSG PPIG PV+ AA FVLD WLRPVP GV GELY+AG GVGVGYWRR GLTA+RF Sbjct 2803 PLTAGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARF 2862 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 +ACPFG G RMYRTGDLV WRADGQL++LGR D+QVK+RGYRIELGE+ AL+ L GV Sbjct 2863 LACPFGEPGTRMYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVE 2922 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QAVV+ARED PGDKRLVGY T G+V PA RA LA+RLP Y+VPAAVVV+D+LP+TV Sbjct 2923 QAVVVAREDNPGDKRLVGYVT----GSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTV 2978 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAP+Y T GYRAP P E+ +AGI+A VLG++RVGVDDSFF+LGGDSL Sbjct 2979 NGKLDTRALPAPDYRHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTT 3038 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDA 2059 MR+I AIN+ L+ DLPVR + A + L+ + + A Sbjct 3039 MRLITAINSALDTDLPVRTVFEAPTIAQLAPRIAQSA 3075 Score = 892 bits (2305), Expect = 0.0, Method: Compositional matrix adjust. Identities = 531/1077 (50%), Positives = 675/1077 (63%), Gaps = 61/1077 (5%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V ++H ++ ++ G + QC L D+SV EIFG Sbjct 3707 AYLIYTSGTTGAPKGVAVTHHNVTQLLGSLD--AGLPSPGVWSQCHSLAFDVSVWEIFGA 3764 Query 635 AACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQ 694 G R+V T L D L+AR T++ + +L G ++++ Sbjct 3765 LLRGGRVVVMPGAVTRSPHDLHDALIARHVTVLTQTPSAVAMLSPQG--LESV------S 3816 Query 695 IVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQ------TTMD 747 +V+ GEA VD+W + G +++ YGPTE ++ V+ P+ + +D Sbjct 3817 LVLAGEACPPEVVDQW-----APGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVD 3871 Query 748 GALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTA----ADGSRR 799 GA L + RP+ P V GE+ + G VA GYLG A A G+R Sbjct 3872 GAALFVLDESLRPVPPGVV----GELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGAR- 3926 Query 800 RAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGS 859 + TGD V A+G + GR D VK+ G R+++ E+ ++ V V + Sbjct 3927 -MYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDN 3985 Query 860 LG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNL 915 G V + + E A R+ +V V +G+ IP PNGK+D+ L Sbjct 3986 PGDKRLVGYITGTADPAEARARLGERLPAYMVPAAV-----LGIDAIPLTPNGKLDARAL 4040 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 P P ++A E+ L+ I++ LG + +G D S G S+ +R++ Sbjct 4041 P-APDYAAGEYRAPESPTEEI-LAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVN 4098 Query 975 RYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWF 1034 L L + + A T A LA P G PL A +RPA +PLSFAQ RLWF Sbjct 4099 AALNADLPVRTVFEAPTVAALA-----PRIGEGGSGLEPLTAGERPAVVPLSFAQNRLWF 4153 Query 1035 LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEA 1094 LDQLQ P+PVYNMA ALRL G LDTEALGAA+ DVV RHESLRT+F A +G P+Q+V+ A Sbjct 4154 LDQLQGPSPVYNMAAALRLDGPLDTEALGAALGDVVARHESLRTLFAAPEGRPQQVVLPA 4213 Query 1095 RRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHH 1154 RAD G ++VDA+ W AD+L AI AR++FDLA +IPLR LFR+ DD HVLVAV HH Sbjct 4214 ERADFGWEVVDASGWSADQLDEAIGATARYTFDLAAQIPLRAELFRLRDDRHVLVAVVHH 4273 Query 1155 IAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAA 1214 IAADG S+APL DL AAYA RC GR PDW PLPVQYVDYTLWQR GDLDD S IAA Sbjct 4274 IAADGMSIAPLVRDLGAAYARRCDGRGPDWTPLPVQYVDYTLWQRAQFGDLDDPGSRIAA 4333 Query 1215 QLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFM 1274 QLAYW++ALAGMPERL LPT RPYP VADQRGA++ +DWPA +QQ++ +AR+HNATSFM Sbjct 4334 QLAYWQDALAGMPERLALPTDRPYPLVADQRGATVEIDWPAELQQRIGDMARRHNATSFM 4393 Query 1275 VVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 V+ L VLL+KL +PDVAVGFPIAGR DPALD+LVGFFVNTLVLRV+ AGDPSF ELL Sbjct 4394 VIQTALTVLLAKLGANPDVAVGFPIAGRRDPALDDLVGFFVNTLVLRVDAAGDPSFTELL 4453 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLG 1388 +VR RSL A+E+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ+ P L+LG Sbjct 4454 ARVRTRSLEAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGQDTGPAAGLSLG 4513 Query 1389 DLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRK 1448 D++ TP+P+DT TARMDL FS+ ER+SE EP GIGG VE+RTDVF+ +I LI RLR+ Sbjct 4514 DVEITPIPVDTHTARMDLTFSVGERWSESGEPGGIGGTVEFRTDVFDPDSIQTLIGRLRR 4573 Query 1449 VLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEA 1508 VL A+ A P ++VSS+D LD E ARLD GNRA LT P P S+P + A Q AR P+A Sbjct 4574 VLEAMTADPTQSVSSVDLLDEREHARLDTLGNRAALTGPPPRFDSLPTLFAEQAARTPDA 4633 Query 1509 EAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAA 1568 A+ CG MTYRELDEA+NR+AH L GAGPG VALLF R A A+VA++ VLK GAA Sbjct 4634 VALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAIVAILGVLKAGAA 4693 Query 1569 YLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG-HDLPIIDVVD-ALAAYPGT 1623 YLPIDPA P R+ FML DA P+ A++TA L RL G HD+P++DV D A+ A P + Sbjct 4694 YLPIDPALPGERIGFMLADAAPLVAISTAELAPRLHGQHDVPVVDVHDPAIEAAPSS 4750 Score = 338 bits (866), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 309/909 (34%), Positives = 427/909 (47%), Gaps = 81/909 (8%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF-----PAVDGVPRQLVIEARRAD 1098 +Y + + L G LD + L AV VV RH L +F V +P +E R + Sbjct 619 MYAVQLDFTLTGPLDADRLREAVRTVVHRHPHLAALFCDQYDEPVQIIPADPAVEWRYVE 678 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L P ++L A E AA DLA + RT L R D H V +HHI D Sbjct 679 LDRTGAADADDPIEQLC-AAERAA--VGDLAGQPVFRTALVRTGGDRHRFVLTSHHILLD 735 Query 1159 GWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAY 1218 GWS+ L ++ A Y + P Y + W E DLD AA+ A Sbjct 736 GWSLPILLREIFAGYYGQRL-------PAAGSYRAFLTWLAE--RDLD------AARRA- 779 Query 1219 WENALAGMPE-RLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVA 1277 W L+G L P R + R P + + +AR + T V+ Sbjct 780 WGEVLSGFDTPTLVAPEGR----LGQGRRGFEKSCVPEQTTRALGELARSCHTTLSTVLQ 835 Query 1278 AGLAVLLSKLSGSPDVAVGFPIAGRSDPALDN---LVGFFVNTLVLRVNLAGDPSFAELL 1334 A AV+L+ L+G DV G P + +D+ +VG +NT+ +R + + A+LL Sbjct 836 AAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLLINTVPVRAEITATTTTAQLL 895 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQ-LNLGDLQAT 1393 Q++ E+Q + + R H L + +++ P+ + LG A Sbjct 896 AQLQNSHNDTLEHQHLALSEI------HRVTGHDQLFDTLFVYENYPIDSGMTLG---AD 946 Query 1394 PMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAV 1453 + I T R + L G E +G +E+ TDVF+ +I+ L++RL++VLVA+ Sbjct 947 GLAIAEFTNREYNHYPLTVEALPGPE---LGLHIEFDTDVFDTASIESLVQRLQRVLVAM 1003 Query 1454 AAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC 1513 + P R +SS+D LD ER + + A ++AP + A +A A+ Sbjct 1004 STDPARRLSSLDLLDRGERELVLSTMSGAGVSAPIGVAPQLLAAAVAADP---DAPAIVD 1060 Query 1514 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPID 1573 G ++YRELDE S RLA +L G GP V + ERCA VVA AV K G Y P++ Sbjct 1061 GARELSYRELDEWSTRLARKLIQHGVGPERAVGVAIERCAELVVAWWAVTKAGGVYAPVN 1120 Query 1574 PANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPA---- 1629 +P RVA +L V V T G PI+ + + T P A Sbjct 1121 LDHPVERVASVL-HTVDAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTEPITDADRRS 1179 Query 1630 ---AVNLAYILYTSGTTGEPKGVGITHRNV------TRLFASLPARLSAAQVWSQCHSYG 1680 A + AY+++TSG+TG PKGV ++H + R L A V S Sbjct 1180 PLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPT---- 1235 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDAS E+ A G L++ P V A LL + V TP ++ L L+ Sbjct 1236 FDASVGELLLAAGSGAALIVAPPQVYAG-EALTALLHNQRVGTAILTPTVISTLDRGRLD 1294 Query 1741 SV-ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTI---CAAISA--PLRPGSGMPPIG 1794 + LV GEAC LVD WAPGR M N YGP+ETTI CA ++A P+R IG Sbjct 1295 GLHTLVAVGEACLPELVDGWAPGRQMFNGYGPSETTIWVTCARLTAGQPVR-------IG 1347 Query 1795 VPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARM 1854 P+ G VLD WL+PVP GV GELY++G +G GY R LTA RFVA PFGG G RM Sbjct 1348 APIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGGPGERM 1407 Query 1855 YRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPG 1914 YRTGDLV W +G L++LGR D+Q+K+RG RIELGE+ L V QA V ++ G Sbjct 1408 YRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQDSAAG 1467 Query 1915 DKRLVGYAT 1923 + LV Y T Sbjct 1468 SQ-LVAYVT 1475 Score = 135 bits (339), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 69/130 (54%), Positives = 94/130 (73%), Gaps = 1/130 (0%) Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKT 1992 A +R +L LP Y+VP +V +D P+T +GKLD +ALPAP+ D + YRAP+ VE+ Sbjct 1891 AQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDDQDADRYRAPSTAVEEI 1950 Query 1993 VAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 + GI+ +VLGLERVGVDDSFF+LGGDSL+AMR+IAA+N +LN DL VR + A + L+ Sbjct 1951 LVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLIAAVNASLNTDLGVRTVFEAPTAAELA 2010 Query 2053 QLLGRDA-RP 2061 +G +A RP Sbjct 2011 LRVGSEADRP 2020 Score = 103 bits (258), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 51/78 (66%), Positives = 64/78 (83%), Gaps = 1/78 (1%) Query 1950 AAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVD 2009 AAVV +DA+PLT NGKLD RALP PEY T YRAP P E+ +AGI+A VLG++RVGVD Sbjct 1 AAVVALDAIPLTPNGKLDTRALPTPEYS-TGEYRAPESPTEEILAGIYAEVLGVDRVGVD 59 Query 2010 DSFFELGGDSLAAMRVIA 2027 +SFFELGGDS+ +++V+A Sbjct 60 ESFFELGGDSILSLQVVA 77 Score = 90.1 bits (222), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 95/309 (31%), Positives = 136/309 (45%), Gaps = 38/309 (12%) Query 569 LLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISV 628 L A TAY++ TSG+TG PK V +SH L + A +G GA VL A T D SV Sbjct 1181 LRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPTFDASV 1240 Query 629 EEIFGGAACGARL-VRSAAMKTGD-LAALVDDLVARETTIVDLPTAVWQLLCADGDAIDA 686 E+ A GA L V + G+ L AL+ + R T + PT + L D +D Sbjct 1241 GELLLAAGSGAALIVAPPQVYAGEALTALLHN--QRVGTAILTPTVISTL---DRGRLDG 1295 Query 687 IGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM 746 L +V GEA VD W + G + + YGP+E T+ T C + T Sbjct 1296 -----LHTLVAVGEACLPELVDGW-----APGRQMFNGYGPSETTIWVT-----CARLTA 1340 Query 747 DGALLRLGRPI-----------LPNTVFLAFGEVVIVGDLVADGYLG---IDGDGFGTVT 792 G +R+G PI L GE+ + G + GYLG + + F Sbjct 1341 -GQPVRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERF-VAN 1398 Query 793 AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVA 852 G R + TGD V EG + GR D +K+ G+R+++ E+ + P V+ A Sbjct 1399 PFGGPGERMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAA 1458 Query 853 VELHSGSLG 861 V + + G Sbjct 1459 VTVQDSAAG 1467 Score = 42.0 bits (97), Expect = 1.7, Method: Compositional matrix adjust. Identities = 115/471 (25%), Positives = 177/471 (38%), Gaps = 97/471 (20%) Query 896 VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDS 954 VV + IP PNGK+D+ LP P++S E+ L+ I++ LG +G D Sbjct 3 VVALDAIPLTPNGKLDTRALP-TPEYSTGEYRAPESPTEEI-LAGIYAEVLGVDRVGVDE 60 Query 955 SLLGEGIGSLDLIRILPETRR----------YLGWRLS-LLDLIGA-DTAANLADYAPTP 1002 S G S+ ++++ R ++ ++ L ++G+ D AA +AD P Sbjct 61 SFFELGGDSILSLQVVARARAAGLTCRPRDVFVEQTVARLARVVGSGDGAAEVADEGVGP 120 Query 1003 DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEAL 1062 PT R+ L AA+R F Q L +Q PA V VA+ L+ +D A+ Sbjct 121 VPPTPIMRW--LQAAERAGGATDQFNQTVL-----VQAPAGVTETEVAIVLQALVDRHAM 173 Query 1063 GAAVADVVGRHESLRTVFPAVDG----VPRQLVIEARRADLGCDIVDATAWPADRLQRAI 1118 LR DG VP ++AR D + A Sbjct 174 -----------LRLRVTDDGADGWSFEVPEAGSVQARDCLRSVDALSDEAL--------- 213 Query 1119 EEAARHSFDLATEIPLRT-WLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRC 1177 AAR + A L W+ L + HH+A D S L DL+ A+A Sbjct 214 -LAARARLNPAAGTMLAALWVEATGQ----LAVIIHHLAVDAVSWWILLEDLNIAWALHR 268 Query 1178 AGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARP 1237 AG+ + AP + W R L D D + QL W+ + P A P Sbjct 269 AGQPVELAP---AGTSFARWAR--LLDEHARDPEVVGQLDRWKTVTS-------TPAALP 316 Query 1238 YP-PVAD--------------QRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAV 1282 P P D + A L+ + PA+ + I +++A GLA Sbjct 317 APRPDVDTYASAGRLSVELDAETTAMLLGEVPAAFHAGIHDI---------LLIAFGLA- 366 Query 1283 LLSKLSGSPDVAVGFPIAGRSDPA-------LDNLVGFFVNTLVLRVNLAG 1326 ++ G P +G + G L VG+F + +++AG Sbjct 367 -WTEFLGEPGAPIGIDVEGHGRHEELGAGIDLSRTVGWFTTKYPVSLDVAG 416 >gi|336462021|gb|EGO40870.1| amino acid adenylation enzyme/thioester reductase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=2378 Score = 1450 bits (3754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 856/1519 (57%), Positives = 1027/1519 (68%), Gaps = 68/1519 (4%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V I+H ++ ++ G A C L D+SV EIFG Sbjct 627 AYVIYTSGTTGVPKGVAITHRNVTQLLGSLDA--GLPAPGVWALCHSLAFDVSVWEIFGA 684 Query 635 AACGARLVRSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRSRLR 693 G RLV T L LVA + +++ P+AV L D ++++ Sbjct 685 LVRGGRLVVVPESVTVSPQELHGMLVAEQVSVLTQTPSAVAAL---PADGLESVA----- 736 Query 694 QIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFL----------PIVCDQ 743 +V+ GEA VD+W + G ++++YGPTE T+ PI Sbjct 737 -LVVVGEACPVEVVDRW-----APGRVMVNAYGPTETTMCVAISAPLKPGSGVPPIGAPV 790 Query 744 TTMDGALL-RLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF-GTVTAADGSR 798 +T +L R RP P V GE+ + G VA GY G+ G F A G+R Sbjct 791 STAALFVLDRWLRPAPPGVV----GELYVAGAGVAVGYTNRAGLTGSRFVACPFGAPGTR 846 Query 799 RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSG 858 + TGD V A+G + GR D VKI G R+++ E+ + V AV Sbjct 847 --MYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEIRSALVGLDGVEQAAVIARED 904 Query 859 SLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDN 914 G V + ++ A R+ L V + VV + +P NGK+D+ Sbjct 905 RPGDKRLVAYVTESATGTADPAEIRARLAQRLPEYMVPAAVVV-LETLPLTANGKLDTRA 963 Query 915 LPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPET 973 LP P + + + A + L+ +++ LG +G D S G SL R++ Sbjct 964 LPA-PGYQNSD-HRAPSSPVEEILAGVFADVLGLDRVGVDDSFFDLGGDSLVATRLIAAI 1021 Query 974 RRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFR--PLVAAQRPAAIPLSFAQRR 1031 L LS+ + A T + LA G DR R PLVA +R A +PLSFAQ+R Sbjct 1022 ETTLNADLSVRAVFEAPTVSQLA-------LCVGSDRGRREPLVAVERLAVVPLSFAQQR 1074 Query 1032 LWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV 1091 LWF+DQLQ P+P+YNMA ALRL G LD +ALG A+ADVV R E+LRT+FPAVDG+P Q+V Sbjct 1075 LWFIDQLQGPSPIYNMAAALRLTGRLDADALGTALADVVARQETLRTLFPAVDGIPEQVV 1134 Query 1092 IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAV 1151 I A RAD G +VDAT WP DRLQ+AIE RHSFDLATEIPLR LFRIADDEHVLVAV Sbjct 1135 IPAERADFGWQVVDATGWPTDRLQQAIEATVRHSFDLATEIPLRARLFRIADDEHVLVAV 1194 Query 1152 AHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSP 1211 HHIAADG S+APL ADL AYASRCAG AP WAPLPVQY DY+LWQR +LGD+ D++SP Sbjct 1195 LHHIAADGLSMAPLVADLGMAYASRCAGHAPGWAPLPVQYADYSLWQRALLGDVADAESP 1254 Query 1212 IAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNAT 1271 +AAQLAYWE LAG+PERL LPT RPYPPVAD RGAS++V+WP +QQ+VR +AR+HNAT Sbjct 1255 MAAQLAYWEQQLAGLPERLALPTDRPYPPVADYRGASVMVEWPTELQQRVRTVAREHNAT 1314 Query 1272 SFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFA 1331 SFMV+ A LAVLL+KLS S D+A GF IAGR +PALD LVGFFVNTLVLRV+LAGDPSF Sbjct 1315 SFMVIQAALAVLLAKLSASRDLATGFAIAGRREPALDELVGFFVNTLVLRVDLAGDPSFT 1374 Query 1332 ELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN------PVGQL 1385 E L QVRARSLAAY++QDVPFEVLV+RL PTR+L HHPL+QV+LAWQ+ P G L Sbjct 1375 ESLAQVRARSLAAYDHQDVPFEVLVERLNPTRSLAHHPLVQVVLAWQNFAREDGVPAG-L 1433 Query 1386 NLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIER 1445 LGDLQ TP+ DT+ ARMDL F+L ER++ EPAGIGG+VE+RTDVF+A+ I LI+R Sbjct 1434 ALGDLQVTPLAADTQVARMDLTFTLGERWTSAGEPAGIGGSVEFRTDVFDAERIPTLIQR 1493 Query 1446 LRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARI 1505 L +VL A+ A P + +SS+D +D E LDE GNR LT PA VSIP M A QV R Sbjct 1494 LERVLAAMTADPGQRLSSVDLMDTDEHIYLDEIGNREALTQPAAR-VSIPAMFADQVIRA 1552 Query 1506 PEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKT 1565 P+A A C SMTYR+LDEASNRLAH L GAGPGE VALLF R A AVVA++AVLKT Sbjct 1553 PQAVATRCAGHSMTYRKLDEASNRLAHLLIEAGAGPGESVALLFNRRAEAVVAVLAVLKT 1612 Query 1566 GAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDA-LAAYPGTP 1624 GAAYLPIDPA+P R+ FM+ DA P+AA+TT L RL G LPIID+ D + +YP T Sbjct 1613 GAAYLPIDPAHPTARIEFMVADAAPIAAITTTELAERLDGCGLPIIDIADPRIDSYPHTA 1672 Query 1625 PPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS-AAQVWSQCHSYGFDA 1683 P+P ++AY++YTSGTTG PKGV ITH NVT L SL L+ QVWSQ HSY FD Sbjct 1673 LPVPDPDDIAYLIYTSGTTGVPKGVAITHNNVTELLGSLAPDLARPGQVWSQWHSYSFDI 1732 Query 1684 SAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVA 1743 S WEI+GALL GGRLV+VPE VAASP+D H LL+ E V+VL QTP+A L QGLESV Sbjct 1733 SGWEIYGALLHGGRLVVVPEEVAASPDDLHALLIDEKVTVLCQTPSAAGTLSPQGLESVT 1792 Query 1744 LVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL---RPGSGMPPIGVPVSGA 1800 L+V GEACP+ LV+RW PGRVM+N YGPTETT+ A+SAPL GS PIG PV GA Sbjct 1793 LLVGGEACPSELVERWGPGRVMINEYGPTETTMWVALSAPLTAGSTGSDAVPIGSPVPGA 1852 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 A FVLD WLRPVPAGV GELY+AG GVGVGY RRAGLTASRFVACPFG SG RMYRTGDL Sbjct 1853 AFFVLDQWLRPVPAGVVGELYVAGTGVGVGYVRRAGLTASRFVACPFGESGTRMYRTGDL 1912 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 V W ADGQL +LGR D+QVKIRGYRIELGE+ +ALA L G+ QA VIAREDRPGDKRLVG Sbjct 1913 VRWGADGQLRYLGRADEQVKIRGYRIELGEIRSALAGLDGIEQAAVIAREDRPGDKRLVG 1972 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Y TE GA DPA +RA+L QRLP Y+VPAAVVV+DALPLTVNGKL+ RALPAPEY + Sbjct 1973 YVTESVTGAADPADIRARLGQRLPAYMVPAAVVVLDALPLTVNGKLNARALPAPEYIERE 2032 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVR 2040 Y APA P E+T+AGI+A+VLGLERVGVDDSFF+LGGDSL+AMRVIAAIN TL+A L VR Sbjct 2033 RYCAPATPTEETLAGIYAQVLGLERVGVDDSFFDLGGDSLSAMRVIAAINKTLDAGLAVR 2092 Query 2041 ALLHASSTRGLSQLLGRDA 2059 L HA S RGL + LG+ A Sbjct 2093 TLFHAPSVRGLCRQLGQGA 2111 Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust. Identities = 524/1118 (47%), Positives = 661/1118 (60%), Gaps = 73/1118 (6%) Query 1023 IPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPA 1082 PL+ Q +W + + + + LR+ G +D L + VV E LR F Sbjct 23 FPLTRGQLDIWLAQETDQQGARWQLGYLLRIEGTVDPWLLEHTIRQVVREAEPLRAAFFQ 82 Query 1083 VDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLA-TEIPLRTWLFRI 1141 VDG Q ++ +L C + Q ++EA R + + T +PL LF+ Sbjct 83 VDGQVFQKAVDYPDVELAC-------YQRMGSQDPVQEAYRLAASIQRTVMPLDGPLFKF 135 Query 1142 A-----DDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYV---- 1192 A DE L HHI ADG +A + + Y + +G AP+P Y Sbjct 136 ALLQTRVDEFYLFVCCHHIVADGIGLALICHRIGDVYNALASG-----APIPPAYFGSLS 190 Query 1193 DYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPER-LRLPTARPYPPVADQRGASLVV 1251 D + E D D AYW L E RL A P + A + + Sbjct 191 DLIACEAEYEASTDYLDD-----RAYWAENLPSESEPGYRLAPASEREPY--ESSAPIEL 243 Query 1252 DWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLS-GSPDVAVGFPIAGRSDPALDNL 1310 D P +V ++++++Q V+AA A+L+ + ++ FP++ R P + Sbjct 244 D-PVAVAG-IQKLSQQLGVRRSSVLAAACALLVGGCDLENSEIVFEFPVSRRVRPEAQTV 301 Query 1311 VGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPL 1370 G + L + + S A V R A ++Q P + ++ + + ++ + Sbjct 302 PGMITGFVPLVLKASPGSSVASFCEHVDTRLGEALQHQRFPVHTIENKRRGSTQTSNRVI 361 Query 1371 IQVMLAWQDNPVGQLNLGDLQATPMP-IDTRTARMDLV----FSLAERFSEGSEPAGIGG 1425 + N + NL ++ + T T +D + FS +R G +P G Sbjct 362 L--------NFIPTTNLANIAGARVSGTLTHTNLVDQLGLDFFSDHDRLFLGMQPGATTG 413 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 + ++ RL +VLVA+ A P R +SS+D L ER RLDE GN+AVL Sbjct 414 GFGGAGQWLSDCDVHDVVGRLERVLVAMTADPGRRLSSVDVLGVGERVRLDELGNKAVLA 473 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 P VSIP + A VA P+A AV S++YR+LDEASNRLAH L G GPGE V Sbjct 474 GPQGVSVSIPDLFARHVAGTPDAVAVSFDGRSVSYRQLDEASNRLAHLLVARGVGPGERV 533 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R AVVA++AVLKTGAAYLPIDP P R+ F+L DA P+AA+T GL RL G Sbjct 534 ALLFSRSVDAVVAILAVLKTGAAYLPIDPGVPDERIGFVLADAAPIAAITGTGLAERLDG 593 Query 1606 HDLPII-----DVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLF 1660 HD+ +I DVV A+ A P T P PA ++AY++YTSGTTG PKGV ITHRNVT+L Sbjct 594 HDVAVIGVDDPDVVPAVDAQPSTGLPGPAPDDVAYVIYTSGTTGVPKGVAITHRNVTQLL 653 Query 1661 ASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEH 1720 SL A L A VW+ CHS FD S WEI+GAL+ GGRLV+VPESV SP + HG+LVAE Sbjct 654 GSLDAGLPAPGVWALCHSLAFDVSVWEIFGALVRGGRLVVVPESVTVSPQELHGMLVAEQ 713 Query 1721 VSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAI 1780 VSVLTQTP+AVA LP GLESVALVV GEACP +VDRWAPGRVM+NAYGPTETT+C AI Sbjct 714 VSVLTQTPSAVAALPADGLESVALVVVGEACPVEVVDRWAPGRVMVNAYGPTETTMCVAI 773 Query 1781 SAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTAS 1840 SAPL+PGSG+PPIG PVS AALFVLD WLRP P GV GELY+AGAGV VGY RAGLT S Sbjct 774 SAPLKPGSGVPPIGAPVSTAALFVLDRWLRPAPPGVVGELYVAGAGVAVGYTNRAGLTGS 833 Query 1841 RFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAG 1900 RFVACPFG G RMYRTGDLV WRADGQL++LGR D+QVKIRGYRIELGE+ +AL L G Sbjct 834 RFVACPFGAPGTRMYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEIRSALVGLDG 893 Query 1901 VGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPL 1960 V QA VIAREDRPGDKRLV Y TE A G DPA +RA+LAQRLP Y+VPAAVVV++ LPL Sbjct 894 VEQAAVIAREDRPGDKRLVAYVTESATGTADPAEIRARLAQRLPEYMVPAAVVVLETLPL 953 Query 1961 TVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSL 2020 T NGKLD RALPAP Y +++ +RAP+ PVE+ +AG+FA VLGL+RVGVDDSFF+LGGDSL Sbjct 954 TANGKLDTRALPAPGYQNSD-HRAPSSPVEEILAGVFADVLGLDRVGVDDSFFDLGGDSL 1012 Query 2021 AAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDP-----RLVSV----- 2070 A R+IAAI TTLNADL VRA+ A + L+ +G D R +P RL V Sbjct 1013 VATRLIAAIETTLNADLSVRAVFEAPTVSQLALCVGSD-RGRREPLVAVERLAVVPLSFA 1071 Query 2071 ----------HGDNPTEVHASDLTLDRFIDADTLATAV 2098 G +P A+ L L +DAD L TA+ Sbjct 1072 QQRLWFIDQLQGPSPIYNMAAALRLTGRLDADALGTAL 1109 >gi|118463736|ref|YP_882241.1| linear gramicidin synthetase subunit D [Mycobacterium avium 104] gi|118165023|gb|ABK65920.1| linear gramicidin synthetase subunit D [Mycobacterium avium 104] Length=10421 Score = 1446 bits (3744), Expect = 0.0, Method: Compositional matrix adjust. Identities = 863/1692 (52%), Positives = 1070/1692 (64%), Gaps = 121/1692 (7%) Query 474 WLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEI 519 +++ GA PG+ + + + I ++A +G Y + D A + Sbjct 3464 FMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIV 3523 Query 520 SVRTNAITEHGDGILVTVVDVA----ATQLAVVGHDELRKVVDERVTQVTHDALLATKTA 575 +V T A+ E G +TV+DVA ATQ A V D A Sbjct 3524 AVTTAALAERLHGFDLTVIDVADPAVATQPATA-----PPVPDP------------DDVA 3566 Query 576 YIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGA 635 +I+ TSGTTG PK V ++ ++A D + Q D SV EI+G Sbjct 3567 HIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWEIWGAL 3626 Query 636 ACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQI 695 G RLV + D LV T++ + LL DG +D + Sbjct 3627 LHGGRLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDG--LDGTA------L 3678 Query 696 VIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVAT----------FLPIVCDQT- 744 VIG E VD+W + G ++++ YGPTE T+ A F PI T Sbjct 3679 VIGAEPCPPELVDRW-----APGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTR 3733 Query 745 ----TMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGS 797 +D L RP+ P V GE+ + GD V GY G+ F + Sbjct 3734 AAFFVLDDWL----RPVPPGVV----GELYLAGDGVGVGYWRRPGLTAARFLACPFGEPG 3785 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 R + TGD V A+G + GR D VK+ G R+++ E+ ++ V V Sbjct 3786 TR-MYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVARE 3844 Query 858 GSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD 913 + G V + + + AA A R+ +V V V + ++P NGK+D+ Sbjct 3845 DNPGDKRLVGYVTGSVAPAKARAALAERLPAYMVPAAV-----VVLDSLPMTVNGKLDTR 3899 Query 914 NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPE 972 LP P + G A L+ I++ LG + +G D S G SL +R++ Sbjct 3900 ALP-APDYRHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITA 3958 Query 973 TRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRL 1032 L L + + A T A LA P PLVAA+RP +PLSFAQ RL Sbjct 3959 INSALDTDLPVRTVFEAPTIAQLA-----PRIAQSAGGLAPLVAAERPDVVPLSFAQNRL 4013 Query 1033 WFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVI 1092 WF+DQ Q P+P+YNMA ALRLRG LD ALGAA+ADVV RHESLRTVFP+ G PRQLV+ Sbjct 4014 WFIDQFQGPSPLYNMAAALRLRGRLDAGALGAALADVVARHESLRTVFPSHQGTPRQLVV 4073 Query 1093 EARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVA 1152 A RA+ G D++DAT WPADRL A+++ RH+FDLA EIP+R LF +++DEHVLV V Sbjct 4074 PAERAEFGWDVIDATDWPADRLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVV 4133 Query 1153 HHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPI 1212 HHIAADG S+ PL DLS AYASRCAG AP WA LPVQY DYTLWQR GDLDD DS I Sbjct 4134 HHIAADGMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLDDPDSRI 4193 Query 1213 AAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATS 1272 QLAYW++ALAGMPERL LPT RPYP VADQRG S+ VDWPA +QQQVRR+AR+HNATS Sbjct 4194 GTQLAYWQDALAGMPERLALPTDRPYPAVADQRGDSVAVDWPAELQQQVRRVAREHNATS 4253 Query 1273 FMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAE 1332 FMVV A LAVLLSK+ S DVAVGFPIAGR DPALD LVGFFVNTLVLR++L GDPSFAE Sbjct 4254 FMVVQAALAVLLSKIGASSDVAVGFPIAGRRDPALDRLVGFFVNTLVLRIDLTGDPSFAE 4313 Query 1333 LLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ-----DNPVGQLNL 1387 LL +V+ARSLAA+E+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ D+P L L Sbjct 4314 LLARVQARSLAAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGHDDPAAALAL 4373 Query 1388 GDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLR 1447 GDL T +P+ ++ARMDLVFSLAER++ E AGIGG VE+RTDVF+A I+ LIERLR Sbjct 4374 GDLDVTSVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRTDVFDAATIETLIERLR 4433 Query 1448 KVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPE 1507 +VL A+ P R +S++D LD ERA L+E GN A+LT PA VS+P++ A QVAR+PE Sbjct 4434 RVLEAMTGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELFATQVARVPE 4493 Query 1508 AEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGA 1567 A+ C D S+TYR+LDEASNRLAHRLA GAGPG+ VALLF R A AV A++AVLKTGA Sbjct 4494 TVALVCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGA 4553 Query 1568 AYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPP 1626 AYLPIDP+ P RV FMLGDA P+AAVTTA L RLAG + ++DV D + P T P Sbjct 4554 AYLPIDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGIDTLPDTALP 4613 Query 1627 MPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAW 1686 +P +AY++YTSGTTG PKGV +TH NVT+L SL A L + VWSQCHS FD S W Sbjct 4614 LPDPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPSPGVWSQCHSLAFDVSVW 4673 Query 1687 EIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVV 1746 EI+GALL GGR+V++PE+VA SP+D H L+A HV+VLTQTP+A+AML QGLESV+LV+ Sbjct 4674 EIFGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSALAMLSPQGLESVSLVL 4733 Query 1747 AGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLD 1806 AGEACP +VD+WAPGRVM+N YGPTET++C +ISAPL GSG+PPIG PV GAALFVLD Sbjct 4734 AGEACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLD 4793 Query 1807 SWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD 1866 LRPVP GV GELY+AG+GV GY R LTA+RFVACPFG ARMYRTGDLV WRAD Sbjct 4794 ESLRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPSARMYRTGDLVRWRAD 4853 Query 1867 GQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIA 1926 GQL++LGR D+QVK+RGYRIELGE+ AL+ L GV QAVV+ARED PGDKRLVGY T Sbjct 4854 GQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYIT--- 4910 Query 1927 PGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPA 1986 G DPA RA+L +RLP Y+VPAAV+ +DA+PLT NGKLD RALPAP+Y YRAP Sbjct 4911 -GTADPAEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDYA-AGEYRAPQ 4968 Query 1987 GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHAS 2046 P E+ +AGI+A VLG++RVGVDDSFF+LGGDS++AMR+IAA+N LNADLPVR + A Sbjct 4969 TPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAP 5028 Query 2047 STRGLSQLLGRDA----------RPTSDPR---------LVSVHGDNPTEVHASDLTLDR 2087 + L+ +G RP P L + G +P A+ L LD Sbjct 5029 TVAALAPRIGEGGSGLEPLTAGERPAVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDG 5088 Query 2088 FIDADTLATAVN 2099 +D + L A+ Sbjct 5089 PLDTEALGAALG 5100 Score = 1429 bits (3699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 803/1485 (55%), Positives = 994/1485 (67%), Gaps = 75/1485 (5%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V ++H ++ ++ G + QC L D+SV EIFG Sbjct 4621 AYLIYTSGTTGAPKGVAVTHHNVTQLLGSLD--AGLPSPGVWSQCHSLAFDVSVWEIFGA 4678 Query 635 AACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQ 694 G R+V L D L+AR T++ + +L G ++++ Sbjct 4679 LLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSALAMLSPQG--LESV------S 4730 Query 695 IVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQ------TTMD 747 +V+ GEA VD+W + G +++ YGPTE ++ V+ P+ + +D Sbjct 4731 LVLAGEACPPEVVDQW-----APGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVD 4785 Query 748 GALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLG--------IDGDGFGTVTAAD 795 GA L + RP+ P V GE+ + G VA GYLG FG +A Sbjct 4786 GAALFVLDESLRPVPPGVV----GELYVAGSGVAAGYLGRPSLTAARFVACPFGAPSA-- 4839 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL 855 R + TGD V A+G + GR D VK+ G R+++ E+ ++ V V Sbjct 4840 ----RMYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVA 4895 Query 856 HSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID 911 + G V + + E A R+ +V V +G+ IP PNGK+D Sbjct 4896 REDNPGDKRLVGYITGTADPAEARARLGERLPAYMVPAAV-----LGLDAIPLTPNGKLD 4950 Query 912 SDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRIL 970 + LP P ++A +T L+ I++ LG + +G D S G S+ +R++ Sbjct 4951 ARALP-APDYAAGEYRAPQTPTEEI-LAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLI 5008 Query 971 PETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQR 1030 L L + + A T A LA P G PL A +RPA +PLSFAQ Sbjct 5009 AAVNAALNADLPVRTVFEAPTVAALA-----PRIGEGGSGLEPLTAGERPAVVPLSFAQN 5063 Query 1031 RLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQL 1090 RLWFLDQLQ P+PVYNMA ALRL G LDTEALGAA+ DVV RHESLRT+F A +G P+Q+ Sbjct 5064 RLWFLDQLQGPSPVYNMAAALRLDGPLDTEALGAALGDVVARHESLRTLFAAPEGRPQQV 5123 Query 1091 VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVA 1150 V+ A RAD G ++VDA+ W AD+L AI AR++FDLA +IPLR LFR+ DD HVLVA Sbjct 5124 VLPAERADFGWEVVDASGWSADQLDEAIGATARYTFDLAAQIPLRAELFRLHDDRHVLVA 5183 Query 1151 VAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDS 1210 V HHIAADG S+ PL DL AAYA RCAG AP W PLPVQYVDYTLWQR GDLDD S Sbjct 5184 VVHHIAADGMSITPLVRDLGAAYARRCAGHAPGWEPLPVQYVDYTLWQRAQFGDLDDPGS 5243 Query 1211 PIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNA 1270 IAAQLAYW++ALAGMPERL LPT RPYP VADQRGA++ +DWPA +QQ++ +AR+HNA Sbjct 5244 RIAAQLAYWQDALAGMPERLALPTDRPYPLVADQRGATVEIDWPAELQQRIGDMARRHNA 5303 Query 1271 TSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSF 1330 TSFMV+ L VLL+KL +PDVAVGFPIAGR DPALD+LVGFFVNTLVLRV+ AGDPSF Sbjct 5304 TSFMVIQTALTVLLAKLGANPDVAVGFPIAGRRDPALDDLVGFFVNTLVLRVDAAGDPSF 5363 Query 1331 AELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQ 1384 ELL +VR RSL A+E+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ+ P Sbjct 5364 TELLARVRTRSLEAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGQDTGPAAG 5423 Query 1385 LNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIE 1444 L+LGD++ TP+P+DT TARMDL FS+ ER+SE EP GIGG VE+RTDVF+ +I LI Sbjct 5424 LSLGDVEITPIPVDTHTARMDLTFSVGERWSESGEPGGIGGTVEFRTDVFDPDSIQTLIG 5483 Query 1445 RLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVAR 1504 RLR+VL A+ A P ++VSS+D LD E ARLD GNRA LT P P S+P + A Q AR Sbjct 5484 RLRRVLEAMTADPTQSVSSVDLLDEREHARLDTLGNRAALTGPPPRFDSLPTLFAEQAAR 5543 Query 1505 IPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLK 1564 P+A A+ CG MTYRELDEA+NR+AH L GAGPG VALLF R A A+VA++ VLK Sbjct 5544 TPDAVALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAIVAILGVLK 5603 Query 1565 TGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG-HDLPIIDVVD-ALAAYPG 1622 +GAAYLPIDPA P R+ FML DA P+ A++TA L RL G HD+P++DV D A+ A P Sbjct 5604 SGAAYLPIDPALPGERIGFMLADAAPLVAISTAELAPRLHGQHDVPVVDVHDPAIEAAPS 5663 Query 1623 TPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFD 1682 + P P A ++AY++YTSGTTG PKGV ++HRNV +L + + L VWSQ HS FD Sbjct 5664 SALPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVAQLLTA-ESGLPREGVWSQWHSLAFD 5722 Query 1683 ASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESV 1742 S WEI+GA L GGRLV++PESVA SP D H LL+ E VSVL+QTP+A L +GLE + Sbjct 5723 VSVWEIFGAQLHGGRLVVIPESVARSPEDLHALLITEQVSVLSQTPSAAGALSPEGLEDL 5782 Query 1743 ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS-GMPPIGVPVSGAA 1801 LVVAGEACP+ LVDRWAPGR M+NAYGPTE T+ AAISAPLRPG+ G PIG PV G A Sbjct 5783 TLVVAGEACPSELVDRWAPGRTMINAYGPTEATVYAAISAPLRPGALGGVPIGSPVPGGA 5842 Query 1802 LFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLV 1861 +FVLD WLRPVP GV GELY+AGAGV GYWRR GLTASRFVACPFG GARMYRTGDLV Sbjct 5843 VFVLDEWLRPVPPGVVGELYVAGAGVACGYWRRGGLTASRFVACPFGAPGARMYRTGDLV 5902 Query 1862 CWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGY 1921 WR DGQL++LGR D+QVKIRGYRIELGEV ALA + GV QAVV+AREDRP DKRLVGY Sbjct 5903 RWRGDGQLDYLGRVDEQVKIRGYRIELGEVRAALAWVDGVDQAVVVAREDRPRDKRLVGY 5962 Query 1922 ATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG 1981 T G DPA +RA LA+RLP Y+VPAAVV +DA+PLT NGKLD RALPAPEY D + Sbjct 5963 IT----GTADPAAVRAALAERLPAYMVPAAVVTLDAIPLTPNGKLDTRALPAPEYSDADR 6018 Query 1982 YRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 YRAP VE+ +AGI+A+VLG++RVGVDDSFF+LGGDS+++M+V+ Sbjct 6019 YRAPDNAVEEILAGIYAQVLGVQRVGVDDSFFDLGGDSISSMQVV 6063 Score = 1404 bits (3634), Expect = 0.0, Method: Compositional matrix adjust. Identities = 866/1703 (51%), Positives = 1063/1703 (63%), Gaps = 146/1703 (8%) Query 402 ERIAAALESMAAMWDRPIAMI----------VNDWFGIGPDGTRCQGDWPARQPSTPAWF 451 ER+ L +M A RP++ I ++DW G R D PA + S PA F Sbjct 6973 ERMRRVLVAMTADPARPLSSIDVLDPAEHQRLHDW------GARAVLDRPATRTSIPALF 7026 Query 452 LDSARGVHQ-----FLGR-----------RRFVYPWVAWLVQRGAAPGDVLVFTDDDTDK 495 A+ Q F GR R + L+ RG PG + + Sbjct 7027 TAQAQRSPQAPAVTFEGRTTTYRELDEASNRLAH----LLIGRGVGPGQAVALLLPRSAD 7082 Query 496 TIDLLIACHLAGCGYSVCDTA----------DEISVRTNAITEHGDGIL----VTVVDVA 541 I ++A G Y D A D+ + T G L +TVVD+ Sbjct 7083 AIVAILAVLKTGAAYLPIDPALPAARIEFMLDDTAPTAAVTTAALAGPLRGRDLTVVDIG 7142 Query 542 ATQLAVVGHDELRKVVDERVTQVTHDALLA---TKTAYIMPTSGTTGQPKLVRISHGSLA 598 D +++ H AL A A+I+ TSGTTG PK V +SH ++ Sbjct 7143 ----------------DRALSRQPHTALPAPDPDHVAHIIYTSGTTGVPKGVAVSHHNVT 7186 Query 599 VFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAMKTGDLAAL 655 DA + A Q D SV EI+G G RLV + A D AL Sbjct 7187 RLFDAQAVGVELSADQVWTQFHSYAFDYSVWEIWGALLHGGRLVVVSDAVARSPMDFHAL 7246 Query 656 VDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAA 715 LVA T++ + ++L G A+ VIG E +D+W Sbjct 7247 ---LVAENVTVLSQTPSAVRMLSPQGLESAAL--------VIGAEPCPPELLDRW----- 7290 Query 716 SQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAF--------- 766 + G ++++ YGPTEAT+ +T +G P+ P T L Sbjct 7291 APGRTMVNVYGPTEATIFST----ASTPLAAGSGAPPIGSPV-PGTALLVLDGWLRPVPA 7345 Query 767 ---GEVVIVGDLVADGYL---GIDGDGF-GTVTAADGSRRRAFATGDRVTVDAEGFPVFS 819 GE+ + G V GYL G+ F A G+R + TGD V A+G + Sbjct 7346 GVVGELYVAGRGVGYGYLRRAGLTASRFVACPFGAPGAR--MYRTGDLVRWRADGQLDYL 7403 Query 820 GRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRTREGEQD 875 GR D VKI G R+++ E+ +A V + V G V + + E Sbjct 7404 GRADEQVKIRGYRIEVGEIRSALAALDGVDEAVVIAREDRPGDKRLVGYITGDADPAEAR 7463 Query 876 AAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRA 935 A A R+ +V + V V + +P NGK+D LP P+++AAG + T Sbjct 7464 ARLAERLPAYMVPVAV-----VVLDALPMTVNGKLDLRALP-APEYAAAGYRSPTTPAEE 7517 Query 936 AGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAAN 994 L+ I++ LG + +G D S G S+ +R++ L + + + A T A Sbjct 7518 I-LAGIYAHVLGVQRVGVDDSFFDLGGDSISAMRVIAAINSALDVGVPVRAIFEAPTVAQ 7576 Query 995 LADYAPTPDAPTGED--RFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALR 1052 LA GED R PL A +RPA +PLSFAQ RLWFLDQLQ P+PVYNMA ALR Sbjct 7577 LAPR-------IGEDAGRLDPLTAGERPAVVPLSFAQSRLWFLDQLQGPSPVYNMAAALR 7629 Query 1053 LRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPAD 1112 + G LD ALGAA+ADVV RHESLRTVF A DG P+Q+V+ A RADLG +V+A W A Sbjct 7630 MHGRLDDRALGAALADVVARHESLRTVFAAPDGTPQQVVLPAERADLGWRVVNARDWSAS 7689 Query 1113 RLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAA 1172 RL+ AI+ AAR +FDLAT+IPLR LFRI +DEHVLVAV HHIAADGWS+ PL DL A Sbjct 7690 RLREAIDAAARETFDLATQIPLRATLFRIGEDEHVLVAVVHHIAADGWSLRPLVRDLGVA 7749 Query 1173 YASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRL 1232 YASRCAG AP W PLPVQYVDYTLWQR G+L DS S IAAQLAYW+ ALAGMPERL L Sbjct 7750 YASRCAGHAPGWEPLPVQYVDYTLWQRAQFGELADSGSRIAAQLAYWQQALAGMPERLAL 7809 Query 1233 PTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPD 1292 PT RPYP +ADQRGA++ VDWPA +QQQV +AR++N+TSFMVV A LAVLL+KLS S D Sbjct 7810 PTDRPYPQLADQRGAAVDVDWPADLQQQVAGLAREYNSTSFMVVQAALAVLLAKLSASTD 7869 Query 1293 VAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPF 1352 VAVGFPIAGR DPALD+LVGFFVNTLVLRV+L+GDPSF ELL +VR RSL A+E+QDVPF Sbjct 7870 VAVGFPIAGRRDPALDDLVGFFVNTLVLRVDLSGDPSFTELLARVRTRSLEAFEHQDVPF 7929 Query 1353 EVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLG-DLQATPMPIDTRTARMD 1405 EVLV+RL PTR+LTHHPL+QVMLAWQ+ +P L LG D++ T MP+DT+ ARMD Sbjct 7930 EVLVERLNPTRSLTHHPLVQVMLAWQNFAGQDADPGAGLALGDDVRVTSMPLDTQVARMD 7989 Query 1406 LVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSID 1465 L FSLAER++E EPAGIGG VE+RTDVF+A I+ LI RL++VL A+ A P ++VSS+D Sbjct 7990 LTFSLAERWTEDDEPAGIGGRVEFRTDVFDADTIETLIRRLQRVLEAMTADPTQSVSSVD 8049 Query 1466 ALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDE 1525 LD E A LD GNRA L+ PA SIP + A Q AR P+A A+ D S TYRELDE Sbjct 8050 LLDAGEHAHLDRIGNRAALSGPAAQFHSIPTVFAEQAARTPDAVALVYEDRSWTYRELDE 8109 Query 1526 ASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFML 1585 A+NRLAHRLAG G G GE VALLF R A A+VA++AVLK GAAYLPIDPA P R+ FML Sbjct 8110 AANRLAHRLAGFGVGAGERVALLFSRSAEAIVAILAVLKAGAAYLPIDPALPDERIGFML 8169 Query 1586 GDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTG 1644 DA P+ A++TA L RL GH + ++DV D A+ P TP P P A ++AY++YTSGTTG Sbjct 8170 ADAAPMVAISTAELAPRLHGHHVVVLDVHDPAVDTQPSTPLPPPGADDIAYLIYTSGTTG 8229 Query 1645 EPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPES 1704 PKGV ++HRNVT+L + + L VWSQ HS FD S WEI+GALL GGRLV++P+S Sbjct 8230 VPKGVAVSHRNVTQLLTA-DSGLPREGVWSQWHSLAFDVSVWEIFGALLHGGRLVVIPDS 8288 Query 1705 VAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRV 1764 V SP+DFH LLV E VSVL+QTP+A L +GLES ALVVAGEACPA LVDRWAPGR Sbjct 8289 VVRSPDDFHALLVDEQVSVLSQTPSAAGTLSPEGLESTALVVAGEACPAELVDRWAPGRT 8348 Query 1765 MLNAYGPTETTICAAISAPLRPGS-GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIA 1823 M+NAYGPTE T+ AISAPL+PGS PIG PV G LFVLD LRPVP GV GELY+A Sbjct 8349 MINAYGPTEATVYTAISAPLQPGSPAGVPIGFPVPGTGLFVLDESLRPVPPGVVGELYVA 8408 Query 1824 GAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRG 1883 GAGV GYWRR GLTASRFVACPFG GARMYRTGDLV WR DGQL++LGR D+QVK+RG Sbjct 8409 GAGVACGYWRRGGLTASRFVACPFGRPGARMYRTGDLVRWRGDGQLDYLGRADEQVKVRG 8468 Query 1884 YRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRL 1943 YRIELGEV +ALA L GV QA V+AREDRPGDKRLVGY T G DPA RA+L +RL Sbjct 8469 YRIELGEVRSALAALDGVDQAAVVAREDRPGDKRLVGYIT----GDADPAEARARLGERL 8524 Query 1944 PGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGL 2003 P Y+VPAA+V +DA+PLT NGKLD RALPAPEY D YRAP PVE+T+A I+A+VLG+ Sbjct 8525 PAYMVPAAIVALDAIPLTPNGKLDTRALPAPEYSDAGQYRAPETPVEQTLAAIYAQVLGV 8584 Query 2004 ERVGVDDSFFELGGDSLAAMRVI 2026 +RVGVDDSFF+LGGDS+++M+V+ Sbjct 8585 QRVGVDDSFFDLGGDSISSMQVV 8607 Score = 1353 bits (3502), Expect = 0.0, Method: Compositional matrix adjust. Identities = 721/1177 (62%), Positives = 857/1177 (73%), Gaps = 24/1177 (2%) Query 896 VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDS 954 +V + P +GK+D LP P + A A + L I+ + LG +G D Sbjct 2824 IVALDEFPMTTSGKLDRKALP-APDYQHADRYRAPSTAVEEILVGIYGQVLGLERVGVDD 2882 Query 955 SLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPL 1014 S G SL +R++ L L + + A TAA LA + DR PL Sbjct 2883 SFFDLGGDSLSAMRLVAAVNASLNTDLGVRTVFEAPTAAELALRVGSE-----ADRPEPL 2937 Query 1015 VAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHE 1074 VA +RPA IPLSFAQ RLWF+DQ Q P+P+YN+ VALRL G LD +AL AA+ADVV RHE Sbjct 2938 VAGERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLSGRLDADALRAALADVVARHE 2997 Query 1075 SLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 SLRTVF DG P+Q+VI A R CD+VDA WP DRL+ A+ AAR++FDL+ E PL Sbjct 2998 SLRTVFATADGTPQQVVIPADRIGFACDVVDARGWPEDRLREAMSAAARYTFDLSAESPL 3057 Query 1135 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDY 1194 T LF DDEHVLV HHIAADGWS+ P DL AYASRC GR PDWAPLPVQY DY Sbjct 3058 HTELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASRCVGRDPDWAPLPVQYADY 3117 Query 1195 TLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP 1254 TLWQR LGD+DD S IAAQL +W +ALAG+PERL+LPT RPYP VAD RGA L VDWP Sbjct 3118 TLWQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERLQLPTDRPYPAVADHRGARLAVDWP 3177 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFF 1314 A +QQQ+RR+AR+HNATSFMVV A A LL+K+S S DVAVGFPIAGR +P LD L+GFF Sbjct 3178 AELQQQLRRVAREHNATSFMVVQAAFAALLAKVSASSDVAVGFPIAGRPEPVLDELIGFF 3237 Query 1315 VNTLVLRVN---LAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 VNTLVLRV+ L GDP+FAELL QVR RSLAA+E+QDVPFE+LV+RL PTR+++HHPL+ Sbjct 3238 VNTLVLRVDLNELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSMSHHPLV 3297 Query 1372 QVMLAWQD------NPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGG 1425 QV+L W++ P L LGDLQ TPMP+ T TARMDL FSLAERF+E + AGI Sbjct 3298 QVLLGWENFPGEVTAPAAGLALGDLQVTPMPLHTNTARMDLTFSLAERFTESGQRAGIAV 3357 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 EYRTDVF+ + ++ LIERL+++L AV A P+R +S++D LD E ARL++WGN AVL Sbjct 3358 TAEYRTDVFDGRTVEGLIERLQRLLTAVTADPQRRLSAVDLLDANEHARLEKWGNTAVLA 3417 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 PA TPVS+P AAQ AR P+A A+ C SMTYRELDEA+NRLAH + GAGPGE V Sbjct 3418 RPA-TPVSVPTRFAAQAARTPDAVALTCDGRSMTYRELDEAANRLAHFMIHHGAGPGERV 3476 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+VA++A LK+GAAYLPIDPA P RV FML DA P+ AVTTA L RL G Sbjct 3477 ALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLHG 3536 Query 1606 HDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL- 1663 DL +IDV D A+A P T PP+P ++A+I+YTSGTTG PKGV +T NV +LF L Sbjct 3537 FDLTVIDVADPAVATQPATAPPVPDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLR 3596 Query 1664 -PARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 LS QVW+Q HSY FD S WEIWGALL GGRLV+VPE+V+ SPN+FH LLV EHV+ Sbjct 3597 IGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDLLVREHVT 3656 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VLTQTP+AV +L T GL+ ALV+ E CP LVDRWAPGR M+N YGPTETT+ A SA Sbjct 3657 VLTQTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRWAPGRTMVNVYGPTETTMWACKSA 3716 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PL GSG PPIG PV+ AA FVLD WLRPVP GV GELY+AG GVGVGYWRR GLTA+RF Sbjct 3717 PLTAGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARF 3776 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 +ACPFG G RMYRTGDLV WRADGQL++LGR D+QVK+RGYRIELGE+ AL+ L GV Sbjct 3777 LACPFGEPGTRMYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVE 3836 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QAVV+ARED PGDKRLVGY T G+V PA RA LA+RLP Y+VPAAVVV+D+LP+TV Sbjct 3837 QAVVVAREDNPGDKRLVGYVT----GSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTV 3892 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAP+Y T GYRAP P E+ +AGI+A VLG++RVGVDDSFF+LGGDSL Sbjct 3893 NGKLDTRALPAPDYRHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTT 3952 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDA 2059 MR+I AIN+ L+ DLPVR + A + L+ + + A Sbjct 3953 MRLITAINSALDTDLPVRTVFEAPTIAQLAPRIAQSA 3989 Score = 828 bits (2138), Expect = 0.0, Method: Compositional matrix adjust. Identities = 514/1034 (50%), Positives = 632/1034 (62%), Gaps = 70/1034 (6%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDI 1103 +Y + + + G LD L AV VV RH +L F R D I Sbjct 6604 LYAGQLDIAIAGPLDAARLRDAVHAVVHRHPNLVARF-------------CDRYDQAVQI 6650 Query 1104 VDATAWPADRL----------QRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAH 1153 + A PA ++ Q +E A DL LR L R A D H L+ H Sbjct 6651 IPAEPAPAWQVVELHGEEQIRQLGADERAAVCADLTESPALRVALVRTATDRHRLLLTNH 6710 Query 1154 HIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIA 1213 HI DGWS+ L ++ AAY + P P Y + W E DLD Sbjct 6711 HIVLDGWSMPILLGEIFAAYYGQRL-------PAPAPYRGFVDWLAE--RDLD------- 6754 Query 1214 AQLAYWENALAGMPERLRLPT-ARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATS 1272 A A W AG PT P PV PA + + V +AR + T Sbjct 6755 AARAAWAEVFAG----FDTPTLVGPQDPVELGPQQVETFTLPADLTRAVTDLARSCHTTV 6810 Query 1273 FMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGDPSF 1330 V+ A A LL L+G DV G ++GR P D +VG +NT+ +R N+ S Sbjct 6811 NTVLQAAFARLLCALTGQRDVVFGTTVSGRPAEVPGADTMVGLLINTVPVRANITATTST 6870 Query 1331 AELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPV--GQLNLG 1388 +LL Q++ ++Q + + R L + A+++ P+ G L+ G Sbjct 6871 VDLLHQLQGAYNHTLDHQHLALNEI------HRITGQDKLFDTLFAYENYPIDAGALS-G 6923 Query 1389 DLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRK 1448 D + + + T+R + L + GS+ + +EY T VF+ + I LIER+R+ Sbjct 6924 DQE---LAVTDITSRESTHYPLTVQAQPGSQ---LRLQIEYATRVFDDEDIATLIERMRR 6977 Query 1449 VLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEA 1508 VLVA+ A P R +SSID LD E RL +WG RAVL PA T SIP + AQ R P+A Sbjct 6978 VLVAMTADPARPLSSIDVLDPAEHQRLHDWGARAVLDRPA-TRTSIPALFTAQAQRSPQA 7036 Query 1509 EAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAA 1568 AV + TYRELDEASNRLAH L G G GPG+ VALL R A A+VA++AVLKTGAA Sbjct 7037 PAVTFEGRTTTYRELDEASNRLAHLLIGRGVGPGQAVALLLPRSADAIVAILAVLKTGAA 7096 Query 1569 YLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPM 1627 YLPIDPA P R+ FML D P AAVTTA L L G DL ++D+ D AL+ P T P Sbjct 7097 YLPIDPALPAARIEFMLDDTAPTAAVTTAALAGPLRGRDLTVVDIGDRALSRQPHTALPA 7156 Query 1628 PAAVNLAYILYTSGTTGEPKGVGITHRNVTRLF--ASLPARLSAAQVWSQCHSYGFDASA 1685 P ++A+I+YTSGTTG PKGV ++H NVTRLF ++ LSA QVW+Q HSY FD S Sbjct 7157 PDPDHVAHIIYTSGTTGVPKGVAVSHHNVTRLFDAQAVGVELSADQVWTQFHSYAFDYSV 7216 Query 1686 WEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALV 1745 WEIWGALL GGRLV+V ++VA SP DFH LLVAE+V+VL+QTP+AV ML QGLES ALV Sbjct 7217 WEIWGALLHGGRLVVVSDAVARSPMDFHALLVAENVTVLSQTPSAVRMLSPQGLESAALV 7276 Query 1746 VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVL 1805 + E CP L+DRWAPGR M+N YGPTE TI + S PL GSG PPIG PV G AL VL Sbjct 7277 IGAEPCPPELLDRWAPGRTMVNVYGPTEATIFSTASTPLAAGSGAPPIGSPVPGTALLVL 7336 Query 1806 DSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRA 1865 D WLRPVPAGV GELY+AG GVG GY RRAGLTASRFVACPFG GARMYRTGDLV WRA Sbjct 7337 DGWLRPVPAGVVGELYVAGRGVGYGYLRRAGLTASRFVACPFGAPGARMYRTGDLVRWRA 7396 Query 1866 DGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEI 1925 DGQL++LGR D+QVKIRGYRIE+GE+ +ALA L GV +AVVIAREDRPGDKRLVGY T Sbjct 7397 DGQLDYLGRADEQVKIRGYRIEVGEIRSALAALDGVDEAVVIAREDRPGDKRLVGYIT-- 7454 Query 1926 APGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAP 1985 G DPA RA+LA+RLP Y+VP AVVV+DALP+TVNGKLD RALPAPEY GYR+P Sbjct 7455 --GDADPAEARARLAERLPAYMVPVAVVVLDALPMTVNGKLDLRALPAPEYA-AAGYRSP 7511 Query 1986 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHA 2045 P E+ +AGI+A VLG++RVGVDDSFF+LGGDS++AMRVIAAIN+ L+ +PVRA+ A Sbjct 7512 TTPAEEILAGIYAHVLGVQRVGVDDSFFDLGGDSISAMRVIAAINSALDVGVPVRAIFEA 7571 Query 2046 SSTRGLSQLLGRDA 2059 + L+ +G DA Sbjct 7572 PTVAQLAPRIGEDA 7585 Score = 817 bits (2111), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/1052 (50%), Positives = 641/1052 (61%), Gaps = 70/1052 (6%) Query 1023 IPLSFAQRRLWFLDQLQRPAP--VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F R +Y + + L L G LD + L A+ V+ RH L F Sbjct 9125 LPLTPLQQGLLFHANTTRGGDDHLYVVQLDLTLTGPLDRDRLREAMHTVISRHPHLGARF 9184 Query 1081 -----PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 V +P + R +L + ++ A +++R +DLA +R Sbjct 9185 CDQFDEPVQVIPADPTMAWRYLELHANGSESDA----QIRRLCAGERAAVYDLAEAPAVR 9240 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R D H LV HHI DGWSV L + A Y + P P Y + Sbjct 9241 AVLIRTGPDRHRLVLTIHHIVLDGWSVPILLNETFACYTGQRL-------PAPAPYRRFV 9293 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDW-- 1253 W E DLD A A W ALAG PT PP + + GA V + Sbjct 9294 TWLAE--RDLD-------AARAAWGEALAG----FDTPTLV-GPPHSLEPGARGVQAFAV 9339 Query 1254 PASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLV 1311 A + + + +AR H+ T V+ A A LL + DVA G ++GR P D++V Sbjct 9340 SAEITRALGELARAHHTTVSTVLQAAWAQLLVWQTAQHDVAFGTTVSGRPAEVPGADSMV 9399 Query 1312 GFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 G +NT+ +R ++ + +LL +++ ++Q + + R L Sbjct 9400 GLMINTVPVRARISAATTTTDLLAELQRGHADTLDHQHLALSEI------HRIAGQDKLF 9453 Query 1372 QVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGA----- 1426 + +++ P L + + +D +L S F P + A Sbjct 9454 DTLFGYENYP--------LDTSALAVD-----HELTISDVNLFERNHYPLTMQAALSGDR 9500 Query 1427 ----VEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRA 1482 VEY +F+A I+ L RL +VL+A+ A P R +SS+D LD +ER RLD+ GNRA Sbjct 9501 LGLRVEYDAGIFDAATIEALSRRLERVLIAMTADPARPLSSVDLLDPSERQRLDDIGNRA 9560 Query 1483 VLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPG 1542 L P P P SIP + AA+ A+ P+A A+ SMTYRELD+A+NRLAH LA GAGPG Sbjct 9561 ALAGPPPAPPSIPVLFAARAAQTPDAVAISWDGLSMTYRELDQAANRLAHLLADHGAGPG 9620 Query 1543 ECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSR 1602 + VALLF R A A+VA++AVLKTGAAYLPID A P RV FML D+ VAAVTTAGLRSR Sbjct 9621 QSVALLFSRSAHAIVAILAVLKTGAAYLPIDAAAPAARVRFMLADSAAVAAVTTAGLRSR 9680 Query 1603 LAGHDLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFA 1661 L G D+ ID+ D + P TP P PA ++AY++YTSGTTG PKGV +THRNVT+L Sbjct 9681 LDGCDVAAIDIEDPRIQTRPSTPLPAPAPHDIAYVIYTSGTTGVPKGVAVTHRNVTQLLE 9740 Query 1662 SLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHV 1721 L A L + VW+Q HSY FD S WEI+GALL GGRLV+VPE+V SP DFH LLV E V Sbjct 9741 PLDAGLPSPGVWTQSHSYAFDVSVWEIFGALLRGGRLVVVPEAVTRSPKDFHALLVDEEV 9800 Query 1722 SVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAIS 1781 +VLTQTP+AVAML +GLESV+LVV GEACPA +VDRWAPGRVM+NAYGPTETT+C AIS Sbjct 9801 TVLTQTPSAVAMLSPEGLESVSLVVVGEACPAEVVDRWAPGRVMVNAYGPTETTMCVAIS 9860 Query 1782 APLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASR 1841 APL PG G PPIGVPV GA LFVLD+WLRPV GV GELY+AGAGV GY R+GLTASR Sbjct 9861 APLAPGMGSPPIGVPVDGAGLFVLDAWLRPVAPGVVGELYVAGAGVAAGYVGRSGLTASR 9920 Query 1842 FVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGV 1901 FVACPFG G RMYRTGDLVCWR DGQL++ GR D+QVK+RGYRIELGEV ALA L V Sbjct 9921 FVACPFGEPGTRMYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDV 9980 Query 1902 GQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLT 1961 QAVVIAREDRPG KRLVGY T G DPA R LAQRLP Y+VP AVV +DA+PLT Sbjct 9981 EQAVVIAREDRPGGKRLVGYIT----GTADPAEARTALAQRLPVYMVPTAVVALDAIPLT 10036 Query 1962 VNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLA 2021 NGK+D RALP PEY + YRAP+ VE+TVAGI+A VLG+ERVG DDSFFELGGDS++ Sbjct 10037 PNGKIDTRALPTPEYTGSR-YRAPSNAVEETVAGIYAHVLGVERVGADDSFFELGGDSIS 10095 Query 2022 AMRVIAAINTTLNADLPVRALLHASSTRGLSQ 2053 AMRVI AIN +L +L VR L A + LS+ Sbjct 10096 AMRVITAINASLGVELAVRTLFEAPTVASLSR 10127 Score = 791 bits (2044), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/1022 (48%), Positives = 610/1022 (60%), Gaps = 53/1022 (5%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A P++ Q +W Q + + V +R+ G +D L A+ VVG ESLR F Sbjct 7 AYPVTRGQLDIWLAQQTGHFDVAWQLGVLVRIDGAIDPALLHQAMRHVVGEAESLRASFF 66 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRI 1141 DG Q +E DL + + P ++ R L + ++ LFR Sbjct 67 EADGQVFQKAVEYSDVDLTFYDLSGSPDPEREVREMAASIQRTPMPLTGPM-IKFALFRT 125 Query 1142 ADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREI 1201 E+ HHIA DG +A + ++A Y + + + P+P + + Q + Sbjct 126 GSAEYYWFTTCHHIAIDGMGIALVGRRIAAVYTALASAK-----PIPPAF--FGSLQDLV 178 Query 1202 LGDLD-DSDSPIAAQLAYW-----ENALAGMPERLRLPTARPYPPVADQRGASLVVDWPA 1255 G+L+ ++ + YW + AG P R PY P S V Sbjct 179 GGELEYEASAKFLEDKDYWLAHRPGDGTAGHPPRPADDGRDPYSP-------SPPVQLDE 231 Query 1256 SVQQQVRRIARQHNATSFMVVAAGLAVLLSKL--SGSPDVAVGFPIAGRSDPALDNLVGF 1313 SV V+ +++ V+ A A+L+ GS +V + FP++ R DP G Sbjct 232 SVIGSVKELSKALGVRRSSVLTAACALLVRGWCADGSDEVVLDFPVSRRVDPKSKTHPGM 291 Query 1314 FVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVD-------RLKPTRALT 1366 + L ++ +FA+ V RS A +Q P L R P R + Sbjct 292 LAGVVPLVLHAPATATFADFCRHVDQRSREALRHQQFPTRTLDGEGDFSGPRQAPNRVVV 351 Query 1367 HHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGA 1426 + + L L+L D+ AT +F L + G G Sbjct 352 N--FVPARLT--------LSLADVPATATYTSFGPVGHFGLFFLGFGDQQFLSTVGTGQP 401 Query 1427 VEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTA 1486 + F+A L ERL+++L A+AA P R +SS+D L E A+L+ GN AVLT Sbjct 402 LAN----FDATD---LAERLQRILAAMAADPARLLSSLDVLRDPEHAQLEALGNTAVLTR 454 Query 1487 PAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVA 1546 VS+P++ A QVAR P+ A+ S+TYR+LDEASNRLAH LAG GAGPG+ VA Sbjct 455 TPGPAVSVPELFATQVARAPQDVALVGEGRSLTYRQLDEASNRLAHLLAGLGAGPGQSVA 514 Query 1547 LLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGH 1606 LLF R A AV +++AVLKTGAAYLPIDPA P R+ FML DA PVAA++TA L RL H Sbjct 515 LLFSRSAEAVASILAVLKTGAAYLPIDPAAPETRIGFMLADAKPVAALSTAELAGRLEAH 574 Query 1607 DLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPA 1665 + +IDV D + P T P+ AA +AY++YTSGTTG PKGV +THRNVT+L SL A Sbjct 575 GMTVIDVNDPRIQDRPATALPVAAADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDA 634 Query 1666 RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLT 1725 L +A VWSQCHSY FD S WEI+GALL GGRLV+VPE+V +P + H +LV E VSVLT Sbjct 635 GLPSAGVWSQCHSYAFDVSVWEIFGALLRGGRLVVVPEAVTRAPEELHDVLVNEQVSVLT 694 Query 1726 QTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLR 1785 QTP+AVAML QGLESV+LVV GEACPA +VDRW+ GRVM+NAYGPTETT+C AISAPL Sbjct 695 QTPSAVAMLSPQGLESVSLVVVGEACPAEVVDRWSGGRVMVNAYGPTETTMCVAISAPLA 754 Query 1786 PGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVAC 1845 PG G PPIGVPV GA LFVLD+WLRPVP GV GELY+ GAGV GY R+GLTASRFVAC Sbjct 755 PGMGSPPIGVPVDGAGLFVLDAWLRPVPPGVVGELYVGGAGVAAGYVGRSGLTASRFVAC 814 Query 1846 PFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAV 1905 PFG GARMYRTGDLVCWR DGQL++ GR D+QVK+RGYRIELGEV ALA L V QAV Sbjct 815 PFGAPGARMYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAV 874 Query 1906 VIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGK 1965 VIAREDRPG KRLVGY T G DPA R LAQRLP Y+VPAAVV +DA+PLT NGK Sbjct 875 VIAREDRPGGKRLVGYIT----GTADPAEARTALAQRLPVYMVPAAVVALDAIPLTPNGK 930 Query 1966 LDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRV 2025 LD RALP PEY T YRAP P E+ +AGI+A VLG++RVGVD+SFFELGGDS+ +++V Sbjct 931 LDTRALPTPEY-STGEYRAPESPTEEILAGIYAEVLGVDRVGVDESFFELGGDSILSLQV 989 Query 2026 IA 2027 +A Sbjct 990 VA 991 Score = 337 bits (865), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 309/909 (34%), Positives = 427/909 (47%), Gaps = 81/909 (8%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF-----PAVDGVPRQLVIEARRAD 1098 +Y + + L G LD + L AV VV RH L +F V +P +E R + Sbjct 1533 MYAVQLDFTLTGPLDADRLREAVRTVVHRHPHLAALFCDQYDEPVQIIPADPAVEWRYVE 1592 Query 1099 LGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 L P ++L A E AA DLA + RT L R D H V +HHI D Sbjct 1593 LDRTGAADADDPIEQLC-AAERAA--VGDLAGQPVFRTALVRTGGDRHRFVLTSHHILLD 1649 Query 1159 GWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAY 1218 GWS+ L ++ A Y + P Y + W E DLD AA+ A Sbjct 1650 GWSLPILLREIFAGYYGQRL-------PAAGSYRAFLTWLAE--RDLD------AARRA- 1693 Query 1219 WENALAGMPE-RLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVA 1277 W L+G L P R + R P + + +AR + T V+ Sbjct 1694 WGEVLSGFDTPTLVAPEGR----LGQGRRGFEKSCVPEQTTRALGELARSCHTTLSTVLQ 1749 Query 1278 AGLAVLLSKLSGSPDVAVGFPIAGRSDPALDN---LVGFFVNTLVLRVNLAGDPSFAELL 1334 A AV+L+ L+G DV G P + +D+ +VG +NT+ +R + + A+LL Sbjct 1750 AAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLLINTVPVRAEITATTTTAQLL 1809 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQ-LNLGDLQAT 1393 Q++ E+Q + + R H L + +++ P+ + LG A Sbjct 1810 AQLQNSHNDTLEHQHLALSEI------HRVTGHDQLFDTLFVYENYPIDSGMTLG---AD 1860 Query 1394 PMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAV 1453 + I T R + L G E +G +E+ TDVF+ +I+ L++RL++VLVA+ Sbjct 1861 GLAIAEFTNREYNHYPLTVEALPGPE---LGLHIEFDTDVFDTASIESLVQRLQRVLVAM 1917 Query 1454 AAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC 1513 + P R +SS+D LD ER + + A ++AP + A +A A+ Sbjct 1918 STDPARRLSSLDLLDRGERELVLSTMSGAGVSAPIGVAPQLLAAAVAADP---DAPAIVD 1974 Query 1514 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPID 1573 G ++YRELDE S RLA +L G GP V + ERCA VVA AV K G Y P++ Sbjct 1975 GARELSYRELDEWSTRLARKLIQHGVGPERAVGVAIERCAELVVAWWAVTKAGGVYAPVN 2034 Query 1574 PANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPA---- 1629 +P RVA +L V V T G PI+ + + T P A Sbjct 2035 LDHPVERVASVL-HTVDAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTEPITDADRRS 2093 Query 1630 ---AVNLAYILYTSGTTGEPKGVGITHRNV------TRLFASLPARLSAAQVWSQCHSYG 1680 A + AY+++TSG+TG PKGV ++H + R L A V S Sbjct 2094 PLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPT---- 2149 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FDAS E+ A G L++ P V A LL + V TP ++ L L+ Sbjct 2150 FDASVGELLLAAGSGAALIVAPPQVYAG-EALTALLHNQRVGTAILTPTVISTLDRGRLD 2208 Query 1741 SV-ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTI---CAAISA--PLRPGSGMPPIG 1794 + LV GEAC LVD WAPGR M N YGP+ETTI CA ++A P+R IG Sbjct 2209 GLHTLVAVGEACLPELVDGWAPGRQMFNGYGPSETTIWVTCARLTAGQPVR-------IG 2261 Query 1795 VPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARM 1854 P+ G VLD WL+PVP GV GELY++G +G GY R LTA RFVA PFGG G RM Sbjct 2262 APIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGGPGERM 2321 Query 1855 YRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPG 1914 YRTGDLV W +G L++LGR D+Q+K+RG RIELGE+ L V QA V ++ G Sbjct 2322 YRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQDSAAG 2381 Query 1915 DKRLVGYAT 1923 + LV Y T Sbjct 2382 SQ-LVAYVT 2389 Score = 135 bits (340), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 68/130 (53%), Positives = 94/130 (73%), Gaps = 1/130 (0%) Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKT 1992 A +R +L LP Y+VP +V +D P+T +GKLD +ALPAP+Y + YRAP+ VE+ Sbjct 2805 AQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDYQHADRYRAPSTAVEEI 2864 Query 1993 VAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 + GI+ +VLGLERVGVDDSFF+LGGDSL+AMR++AA+N +LN DL VR + A + L+ Sbjct 2865 LVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLVAAVNASLNTDLGVRTVFEAPTAAELA 2924 Query 2053 QLLGRDA-RP 2061 +G +A RP Sbjct 2925 LRVGSEADRP 2934 Score = 110 bits (276), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 214/815 (27%), Positives = 323/815 (40%), Gaps = 142/815 (17%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A AY++ TSGTTG PK V ++H ++ ++ G + QC D+SV E Sbjct 599 ADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLD--AGLPSAGVWSQCHSYAFDVSVWE 656 Query 631 IFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRS 690 IFG G RLV T L D LV + +++ + +L G ++++ Sbjct 657 IFGALLRGGRLVVVPEAVTRAPEELHDVLVNEQVSVLTQTPSAVAMLSPQG--LESV--- 711 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTT---- 745 +V+ GEA VD+W S G ++++YGPTE T+ VA P+ + Sbjct 712 ---SLVVVGEACPAEVVDRW-----SGGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIG 763 Query 746 --MDGALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTA----AD 795 +DGA L + RP+ P V GE+ + G VA GY+G G A A Sbjct 764 VPVDGAGLFVLDAWLRPVPPGVV----GELYVGGAGVAAGYVGRSGLTASRFVACPFGAP 819 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV-- 853 G+R + TGD V +G + GR D VK+ G R+++ EV +A V V Sbjct 820 GAR--MYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIA 877 Query 854 --ELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKID 911 + G V + + E A A R+ + +V V V + IP PNGK+D Sbjct 878 REDRPGGKRLVGYITGTADPAEARTALAQRLPVYMVPAAV-----VALDAIPLTPNGKLD 932 Query 912 SDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRIL 970 + LP P++S E+ L+ I++ LG +G D S G S+ ++++ Sbjct 933 TRALP-TPEYSTGEYRAPESPTEEI-LAGIYAEVLGVDRVGVDESFFELGGDSILSLQVV 990 Query 971 PETRRY-LGWR----------LSLLDLIGA-DTAANLADYAPTPDAPTGEDRFRPLVAAQ 1018 R L R L ++G+ D AA +AD P PT R+ L AA+ Sbjct 991 ARARAAGLTCRPRDVFVEQTVARLARVVGSGDGAAEVADEGVGPVPPTPIMRW--LQAAE 1048 Query 1019 RPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRT 1078 R F Q L +Q PA V VA+ L+ +D A+ LR Sbjct 1049 RAGGATDQFNQTVL-----VQAPAGVTETEVAIVLQALVDRHAM-----------LRLRV 1092 Query 1079 VFPAVDG----VPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 DG VP ++AR D + A AAR + A L Sbjct 1093 TDDGADGWSFEVPEAGSVQARDCLRSVDALSDEAL----------LAARARLNPAAGTML 1142 Query 1135 RT-WLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVD 1193 W+ L + HH+A D S L DL+ A+A AG+ + AP Sbjct 1143 AALWVEATGQ----LAVIIHHLAVDAVSWWILLEDLNIAWALHRAGQPVELAP---AGTS 1195 Query 1194 YTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYP-PVAD--------- 1243 + W R L D D + QL W+ + P A P P P D Sbjct 1196 FARWAR--LLDEHARDPEVVGQLDRWKTVTS-------TPAALPAPRPDVDTYASAGRLS 1246 Query 1244 -----QRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFP 1298 + A L+ + PA+ + I +++A GLA ++ G P +G Sbjct 1247 VELDAETTAMLLGEVPAAFHAGIHDI---------LLIAFGLA--WTEFLGEPGAPIGID 1295 Query 1299 IAGRSDPA-------LDNLVGFFVNTLVLRVNLAG 1326 + G L VG+F + +++AG Sbjct 1296 VEGHGRHEELGAGIDLSRTVGWFTTKYPVSLDVAG 1330 Score = 107 bits (266), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 129/455 (29%), Positives = 201/455 (45%), Gaps = 50/455 (10%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V ++H ++ + + G + Q D+SV EIFG Sbjct 9713 AYVIYTSGTTGVPKGVAVTHRNVTQLLEPLD--AGLPSPGVWTQSHSYAFDVSVWEIFGA 9770 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 G RLV + D AL LV E T++ + +L +G ++++ Sbjct 9771 LLRGGRLVVVPEAVTRSPKDFHAL---LVDEEVTVLTQTPSAVAMLSPEG--LESV---- 9821 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTT----- 745 +V+ GEA VD+W + G ++++YGPTE T+ VA P+ + Sbjct 9822 --SLVVVGEACPAEVVDRW-----APGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIGV 9874 Query 746 -MDGALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSR-- 798 +DGA L + RP+ P V GE+ + G VA GY+G G A Sbjct 9875 PVDGAGLFVLDAWLRPVAPGVV----GELYVAGAGVAAGYVGRSGLTASRFVACPFGEPG 9930 Query 799 RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV----E 854 R + TGD V +G + GR D VK+ G R+++ EV +A V V + Sbjct 9931 TRMYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIARED 9990 Query 855 LHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDN 914 G V + + E A A R+ + +V VV + IP PNGKID+ Sbjct 9991 RPGGKRLVGYITGTADPAEARTALAQRLPVYMVPTA-----VVALDAIPLTPNGKIDTRA 10045 Query 915 LPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPET 973 LP P+++ + A + ++ I++ LG +G D S G S+ +R++ Sbjct 10046 LP-TPEYTGSRYR-APSNAVEETVAGIYAHVLGVERVGADDSFFELGGDSISAMRVITAI 10103 Query 974 RRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGE 1008 LG L++ L A T A+L+ A T A G+ Sbjct 10104 NASLGVELAVRTLFEAPTVASLSRRAQTDTARGGQ 10138 Score = 102 bits (253), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 173/643 (27%), Positives = 251/643 (40%), Gaps = 90/643 (13%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A AY++ TSGTTG PK V +SH ++ A S G Q L D+SV E Sbjct 8215 ADDIAYLIYTSGTTGVPKGVAVSHRNVTQLLTADS---GLPREGVWSQWHSLAFDVSVWE 8271 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 IFG G RLV S D AL LV + +++ + L +G A+ Sbjct 8272 IFGALLHGGRLVVIPDSVVRSPDDFHAL---LVDEQVSVLSQTPSAAGTLSPEGLESTAL 8328 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMD 747 V+ GEA VD+W + G +++++YGPTEATV + I Sbjct 8329 --------VVAGEACPAELVDRW-----APGRTMINAYGPTEATV---YTAISAPLQPGS 8372 Query 748 GALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAADG 796 A + +G P+ +F+ GE+ + G VA GY G A Sbjct 8373 PAGVPIGFPVPGTGLFVLDESLRPVPPGVVGELYVAGAGVACGYWRRGGLTASRFVACPF 8432 Query 797 SR--RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVE 854 R R + TGD V +G + GR D VK+ G R+++ EV +A V AV Sbjct 8433 GRPGARMYRTGDLVRWRGDGQLDYLGRADEQVKVRGYRIELGEVRSALAALDGVDQAAVV 8492 Query 855 LHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKI 910 G V + + E A R+ +V + V + IP PNGK+ Sbjct 8493 AREDRPGDKRLVGYITGDADPAEARARLGERLPAYMVPAAI-----VALDAIPLTPNGKL 8547 Query 911 DSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRI 969 D+ LP P++S AG A L+ I+++ LG + +G D S G S+ +++ Sbjct 8548 DTRALP-APEYSDAGQYRAPETPVEQTLAAIYAQVLGVQRVGVDDSFFDLGGDSISSMQV 8606 Query 970 LPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAP-------TGEDRFRPLVAAQRPAA 1022 + + G + D+ T A LA A D TGE P++ R Sbjct 8607 VTRAK-AAGLAVRTRDIFTEQTVARLARVAGVADEDGGPADEGTGEVTATPIIEWLRGVN 8665 Query 1023 IPL-SFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGR--HESLRTV 1079 P+ F Q + LQ PA V V L+ LD A+ D SL+ Sbjct 8666 GPVDEFNQTMV-----LQAPAGVTEADVVAVLQALLDRHAMLRLRVDTAADTGEWSLQVP 8720 Query 1080 FP-AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRT-W 1137 P +VD R + D L A AR + A + L W Sbjct 8721 EPGSVDAAQRVHTV-------------------DELSDAAIIEARSRLNPAAGVMLSALW 8761 Query 1138 LFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGR 1180 + LV + HH+A DG S L DL+ A+ G+ Sbjct 8762 VGSTGR----LVLIIHHLAVDGVSWRVLLEDLNIAWGQHHNGQ 8800 Score = 99.0 bits (245), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 196/702 (28%), Positives = 278/702 (40%), Gaps = 100/702 (14%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A AY++ TSGTTG PK V +SH ++A A S G Q L D+SV E Sbjct 5671 ADDIAYLIYTSGTTGVPKGVAVSHRNVAQLLTAES---GLPREGVWSQWHSLAFDVSVWE 5727 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 IFG G RLV S A DL AL L+ + +++ Q A G A+ Sbjct 5728 IFGAQLHGGRLVVIPESVARSPEDLHAL---LITEQVSVLS------QTPSAAG-ALSPE 5777 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF----------- 736 G L +V+ GEA VD+W + G +++++YGPTEATV A Sbjct 5778 GLEDL-TLVVAGEACPSELVDRW-----APGRTMINAYGPTEATVYAAISAPLRPGALGG 5831 Query 737 LPIVCDQTTMDGALLRLG---RPILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGF-G 789 +PI GA+ L RP+ P V GE+ + G VA GY G+ F Sbjct 5832 VPI--GSPVPGGAVFVLDEWLRPVPPGVV----GELYVAGAGVACGYWRRGGLTASRFVA 5885 Query 790 TVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIA----ED 845 A G+R + TGD V +G + GR D VKI G R+++ EV +A D Sbjct 5886 CPFGAPGAR--MYRTGDLVRWRGDGQLDYLGRVDEQVKIRGYRIELGEVRAALAWVDGVD 5943 Query 846 PAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRK 905 AV + V + + AA A R+ +V V V + IP Sbjct 5944 QAVVVAREDRPRDKRLVGYITGTADPAAVRAALAERLPAYMVPAAV-----VTLDAIPLT 5998 Query 906 PNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSL 964 PNGK+D+ LP P++S A A L+ I+++ LG + +G D S G S+ Sbjct 5999 PNGKLDTRALP-APEYSDADRYRAPDNAVEEILAGIYAQVLGVQRVGVDDSFFDLGGDSI 6057 Query 965 DLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAP------TGEDRFRPLVAAQ 1018 ++++ R G D+ T A LA A DA GE P++ Sbjct 6058 SSMQVVTRAR-AAGLVCKTRDIFVEQTVARLARVAEVADADAAADEGVGEITATPII--- 6113 Query 1019 RPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRT 1078 R L ++ +N A+ +R + + + ++ RH LR Sbjct 6114 -----------RWLQDVESAGGQVDQFNQAMLVRAPAGVTEADVVTVLQALLDRHAMLRL 6162 Query 1079 VFPAVD--GVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR- 1135 D G V E D G A D L A AR + A + L Sbjct 6163 RVERDDATGEWSLQVPEPGSVDAG-----ACLHAVDELSDAAVIEARSRLNPAAGVMLSA 6217 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 W A+ LV + HH+A DG S L DL+ A+A G+ LP + Sbjct 6218 VW----ANATGQLVVIIHHLAVDGVSWRILLQDLNIAWAQHHGGQP---VALPAAGTSFA 6270 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARP 1237 W + G D +A + W+ A P LP RP Sbjct 6271 RWASRLAGHAHHPD--VADRAGAWQAVAATPPA---LPAVRP 6307 Score = 90.1 bits (222), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 95/309 (31%), Positives = 136/309 (45%), Gaps = 38/309 (12%) Query 569 LLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISV 628 L A TAY++ TSG+TG PK V +SH L + A +G GA VL A T D SV Sbjct 2095 LRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPTFDASV 2154 Query 629 EEIFGGAACGARL-VRSAAMKTGD-LAALVDDLVARETTIVDLPTAVWQLLCADGDAIDA 686 E+ A GA L V + G+ L AL+ + R T + PT + L D +D Sbjct 2155 GELLLAAGSGAALIVAPPQVYAGEALTALLHN--QRVGTAILTPTVISTL---DRGRLDG 2209 Query 687 IGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM 746 L +V GEA VD W + G + + YGP+E T+ T C + T Sbjct 2210 -----LHTLVAVGEACLPELVDGW-----APGRQMFNGYGPSETTIWVT-----CARLTA 2254 Query 747 DGALLRLGRPI-----------LPNTVFLAFGEVVIVGDLVADGYLG---IDGDGFGTVT 792 G +R+G PI L GE+ + G + GYLG + + F Sbjct 2255 -GQPVRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERF-VAN 2312 Query 793 AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVA 852 G R + TGD V EG + GR D +K+ G+R+++ E+ + P V+ A Sbjct 2313 PFGGPGERMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAA 2372 Query 853 VELHSGSLG 861 V + + G Sbjct 2373 VTVQDSAAG 2381 >gi|342860686|ref|ZP_08717336.1| linear gramicidin synthetase subunit D [Mycobacterium colombiense CECT 3035] gi|342131710|gb|EGT84967.1| linear gramicidin synthetase subunit D [Mycobacterium colombiense CECT 3035] Length=10426 Score = 1436 bits (3718), Expect = 0.0, Method: Compositional matrix adjust. Identities = 844/1591 (54%), Positives = 1046/1591 (66%), Gaps = 78/1591 (4%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L++RG PG+ + + I ++A G Y D A + +T D Sbjct 7060 LIERGVGPGEAVALLFGKSADAIVAILAVLKTGAAYLPIDPALPAARIDFMLT---DTAP 7116 Query 535 VTVVDVAATQLAVVGHDELRKVVDER-VTQVTHDALLA---TKTAYIMPTSGTTGQPKLV 590 + + VAA + HD + +++R V + AL A A+I+ TSGTTG PK V Sbjct 7117 MAAITVAALADKLDAHDLIVIDINDRAVARKPRTALPAPAPEHVAHIIYTSGTTGVPKGV 7176 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAM 647 +SH ++ DA + A Q D SV EI+G G RLV S A Sbjct 7177 AVSHRNVTRLFDAQAVGVTLSADQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPDSVAR 7236 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAV 707 + AL LVA + T++ + ++L G A+ VIG E V Sbjct 7237 SPMEFHAL---LVAEKVTVLSQTPSAVRMLSPQGLESAAL--------VIGAEPCPPELV 7285 Query 708 DKWLESAASQGISLLSSYGPTEATVVATF-LPIVCDQ------TTMDGALLRLG----RP 756 D+W + G ++L+ YGPTEAT+ ++ P+ +++ GA L + RP Sbjct 7286 DRW-----APGRTMLNVYGPTEATIFSSMSTPLAAGSGAPPIGSSVPGAALFVLDGWLRP 7340 Query 757 ILPNTVFLAFGEVVIVGDLVADGYL---GIDGDGFGTVTAAD-GSRRRAFATGDRVTVDA 812 + V GE+ + G V GY+ G+ F + GSR + TGD V Sbjct 7341 VAAGVV----GELYVAGRGVGYGYVRRPGLTATRFVPCPFGEPGSR--MYRTGDLVCWGP 7394 Query 813 EGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREG 872 +G + GR D VKI G R+++ EV +A V V G Sbjct 7395 DGQLQYFGRADEQVKIRGYRIEVGEVRSALAALDGVEQAVVIAREDRPGDKRLVGYVIGD 7454 Query 873 EQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETG 932 A A T++ L V + VV + +P NGK+D LP P++SAAG + T Sbjct 7455 ADPAEARTQLADRLPGYMVPAAVVV-LEALPMTLNGKLDIRALPA-PEYSAAGYRSPTTP 7512 Query 933 QRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADT 991 L+ I++ LG +G D S G S+ +R++ + +++ + + T Sbjct 7513 TEEI-LAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVIAAVNSAMDVGVAVRVIFESPT 7571 Query 992 AANLADYAPTPDAPTGED--RFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAV 1049 A LA GED R PLVA +RPA IPLSFAQ RLWFLDQLQ P+PVYNMA Sbjct 7572 VAQLAPR-------IGEDSGRLDPLVAGERPAVIPLSFAQSRLWFLDQLQGPSPVYNMAA 7624 Query 1050 ALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAW 1109 ALRL G LD ALGAA+ADVV RHESLRTVF A D P+Q+VI +ADL V+A W Sbjct 7625 ALRLHGRLDARALGAALADVVARHESLRTVFAATDDTPQQVVIPVEQADLSWRTVNARGW 7684 Query 1110 PADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADL 1169 A RL+ A++ AAR +FDLAT+IPLR LFR+ DDEHVLVAV HHIAADGWS+ PL DL Sbjct 7685 SAGRLREAVDAAARETFDLATQIPLRASLFRVDDDEHVLVAVVHHIAADGWSLRPLVRDL 7744 Query 1170 SAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPER 1229 AYASRCAGRAPDW PL VQYVDYTLWQR G+L DS S IA QLAYW++ALAGMPER Sbjct 7745 GMAYASRCAGRAPDWEPLAVQYVDYTLWQRAQFGELADSGSRIAGQLAYWQDALAGMPER 7804 Query 1230 LRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSG 1289 L+LPT RPYPPVADQRGA++ VDWPA +QQQ+ +AR++N+TSFMVV A LAVLLSK+S Sbjct 7805 LQLPTDRPYPPVADQRGAAVEVDWPADLQQQIAGLAREYNSTSFMVVQAALAVLLSKISA 7864 Query 1290 SPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQD 1349 S DVAVGFPIAGR DPAL++LVGFFVNTLVLRV+LAGDPSF ELL +VRARSL A+E+QD Sbjct 7865 STDVAVGFPIAGRRDPALEDLVGFFVNTLVLRVDLAGDPSFTELLTRVRARSLEAFEHQD 7924 Query 1350 VPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLG-DLQATPMPIDTRTA 1402 VPFEVLV+R+ PTR+LTHHPL+QVMLAWQ+ P L LG D+Q T +P+DT+ A Sbjct 7925 VPFEVLVERVNPTRSLTHHPLVQVMLAWQNFAGQDSEPGAGLALGDDVQVTSIPLDTQVA 7984 Query 1403 RMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVS 1462 RMDLVFSLAER++E +EPAGIGG VE+RTDVF+A+ I+ LI RL++VL A+ A P R +S Sbjct 7985 RMDLVFSLAERWAEDNEPAGIGGRVEFRTDVFDAETIETLIARLQRVLEAMTADPTRALS 8044 Query 1463 SIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRE 1522 ++D LD E ARLD GNRAVLTAPA S+P + A QVAR+P+A A+ C D S TYRE Sbjct 8045 TVDLLDRREHARLDALGNRAVLTAPATVDASVPALFAEQVARVPDAVALRCEDRSWTYRE 8104 Query 1523 LDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVA 1582 DEA++RLA RLAG G G GE VALLF R A A+VA++AVLK GAAYLPIDPA P R+ Sbjct 8105 FDEAADRLARRLAGLGVGRGERVALLFGRSAEAIVAILAVLKAGAAYLPIDPALPAERIG 8164 Query 1583 FMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA----AYPGTPPPMPAAVNLAYILY 1638 FMLGDA P+ A++TA L RL GH +P+IDV D A A P TP P P+ ++AY++Y Sbjct 8165 FMLGDAAPMVAISTAELAERLYGHHVPVIDVGDVDAPGVDAQPATPLPAPSPDDIAYLIY 8224 Query 1639 TSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRL 1698 TSGTTG PKGV + HRNV +L AS + L VWSQ HS FD S WEI+GALL GGRL Sbjct 8225 TSGTTGVPKGVAVAHRNVAQLLASGESGLPHEGVWSQWHSLAFDVSVWEIFGALLQGGRL 8284 Query 1699 VIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDR 1758 V++P++V SP DFH LLVAE V+V++QTP+A +L +GLES ALVVAGEACPA LVDR Sbjct 8285 VVIPDAVVRSPEDFHALLVAEGVTVISQTPSAADVLSPEGLESAALVVAGEACPAELVDR 8344 Query 1759 WAPGRVMLNAYGPTETTICAAISAPLRPGSGMP---PIGVPVSGAALFVLDSWLRPVPAG 1815 WAPGR M+NAYGPTE T+ AA+SAPL+ G+ PIG PV GAA FVLD +LRPVP G Sbjct 8345 WAPGRAMINAYGPTEATVYAAVSAPLQAGAAANAPVPIGSPVPGAAAFVLDEFLRPVPHG 8404 Query 1816 VAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRT 1875 V GELY+AG GV VGYWRRA LTASRFVACPFG GARMYRTGDLV W +DGQL++LGR Sbjct 8405 VVGELYVAGGGVAVGYWRRAELTASRFVACPFGAPGARMYRTGDLVRWGSDGQLQYLGRA 8464 Query 1876 DDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGL 1935 D+QVKIRGYRIELGEV +ALA L GV QAVVIAREDRPGDKRLVGY T G DP + Sbjct 8465 DEQVKIRGYRIELGEVRSALAALDGVEQAVVIAREDRPGDKRLVGYIT----GGADPVEI 8520 Query 1936 RAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAG 1995 R +LA LP Y+VPAAVV ++ALPLT NGKLD RALPAPEY D + YRAP PVE+T+AG Sbjct 8521 RTRLADHLPAYMVPAAVVTLEALPLTANGKLDVRALPAPEYRDVDRYRAPGSPVEETLAG 8580 Query 1996 IFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 I+A+VLG++RVG+DDSFF+LGGDS+++M+V+ Sbjct 8581 IYAQVLGVDRVGIDDSFFDLGGDSISSMQVV 8611 Score = 1430 bits (3701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 862/1692 (51%), Positives = 1063/1692 (63%), Gaps = 120/1692 (7%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEIS 520 LV RGA PG+ + + I ++A +G Y + D + Sbjct 3449 LVDRGAGPGESVALLFSRSADAIVAILAVLKSGAAYLPIDPALPATRVEFMLTDAGPTAA 3508 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 V T + + DG +TVVDVA +A A T A+I+ T Sbjct 3509 VTTAELADRFDGFDLTVVDVADPAVATR-------------PSTAPPAPAPTDLAHIIYT 3555 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V ++ ++A D + + A Q D SV EI+G G R Sbjct 3556 SGTTGVPKGVAVTQHNVAQLFDDLRLGFALSAEQVWTQFHSYAFDFSVWEIWGALLHGGR 3615 Query 641 LV--RSAAMKTGDLAALVDDLVARE--TTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIV 696 LV A ++ + L+ RE T + P+AV LL DG +DA +V Sbjct 3616 LVIVPEAVSRSPEE---FHTLLVREGVTVLTQTPSAV-GLLPTDG--LDAT------SLV 3663 Query 697 IGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGA--LLRLG 754 IG E VD+W + G +++ YGPTE T+ A C T + +G Sbjct 3664 IGAEPCPPELVDRW-----APGRVMVNVYGPTETTMWA------CKSTPLQAGSGFPPIG 3712 Query 755 RPILPNTVFL-----------AFGEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRR 800 P+ F+ GE+ + G V GY G+ F + R Sbjct 3713 SPVTRAAFFVLDEWLRPVPAGVVGELYLAGQGVGVGYWRRPGLTASRFMACPFGEPGTR- 3771 Query 801 AFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSL 860 + TGD V +G + GR D VK+ G R+++ E+ ++ V V Sbjct 3772 MYRTGDLVCWGPDGQLRYFGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDRP 3831 Query 861 G----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLP 916 G V + + G AA A R+ +V V V + +P NGK+D+ LP Sbjct 3832 GDKRLVGYVTGSADPGAARAAVAERLPAYMVPAAV-----VVLDALPVTVNGKLDARALP 3886 Query 917 RLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRR 975 P + A A + L+ I+++ LG +G D S G SL +R++ Sbjct 3887 A-PDYRAVDNYRAPSTAVEEILAGIYAQVLGVERVGVDDSFFDLGGDSLSTMRLVTAINA 3945 Query 976 YLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFL 1035 L L + + A T A LA P A PLVA +RP +PLSFAQ RLWF+ Sbjct 3946 ALHSDLPVRVVFEAPTVAQLA-----PRAAESAGGLEPLVAGERPPVVPLSFAQNRLWFI 4000 Query 1036 DQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEAR 1095 DQ Q P+P+YNMA ALRLRG LD EALGAA+ADVVGRHESLRT+FPA +G P+Q+V+ A Sbjct 4001 DQFQGPSPLYNMAAALRLRGRLDAEALGAALADVVGRHESLRTLFPAHEGTPQQVVVPAE 4060 Query 1096 RADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHI 1155 RA+ G D+VDATAWPA RL AI+ A R++FDLA EIP+R LF +A+DEHVLV V HHI Sbjct 4061 RAEFGWDVVDATAWPAGRLDDAIKAATRYTFDLAAEIPMRAQLFAVAEDEHVLVIVVHHI 4120 Query 1156 AADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQ 1215 AADG S+ PL ADLS AY RCAG AP+WA LPVQY+DYTLWQR GDLDDS S I +Q Sbjct 4121 AADGLSLTPLGADLSVAYTGRCAGHAPEWAELPVQYIDYTLWQRAQFGDLDDSASRIGSQ 4180 Query 1216 LAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMV 1275 LAYWE LAGMPERL+LPT RPYPPVADQRG S+VVDWPA +Q+QVRR+AR+HNATSFMV Sbjct 4181 LAYWEQVLAGMPERLQLPTDRPYPPVADQRGDSVVVDWPAELQEQVRRLAREHNATSFMV 4240 Query 1276 VAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLG 1335 V A LAVLLSK+ S DVAVGFPIAGR DPALD LVGFFVNTLVLR++LAGDPSFAELL Sbjct 4241 VQAALAVLLSKIGASSDVAVGFPIAGRRDPALDRLVGFFVNTLVLRIDLAGDPSFAELLE 4300 Query 1336 QVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ-----DNPVGQLNLGDL 1390 +V+ RSL A+E+QDVPFEVLV+R+ PTR+LTHHPL+QVMLAWQ D+P L LGDL Sbjct 4301 RVQGRSLEAFEHQDVPFEVLVERVNPTRSLTHHPLVQVMLAWQNFAGHDDPAAGLALGDL 4360 Query 1391 QATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVL 1450 + +P++ ++ARMDLVFSLAER++ E AGIGG VE+RTDVF+A I+ LI RLR+VL Sbjct 4361 EVASVPVEDQSARMDLVFSLAERWNAAGEAAGIGGRVEFRTDVFDAATIETLIARLRRVL 4420 Query 1451 VAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEA 1510 A+ A P +SS+D LD E ARL E GN VLT PA P S+P++ A VA P+A A Sbjct 4421 TAMTADPTHLLSSVDLLDEAEHARLKELGNNGVLTRPAGAPTSVPELFATHVAGTPDAVA 4480 Query 1511 VCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYL 1570 + C S+TYR+LDEASNRLAH L GAGPG+ VALLF R A A+ +++AVLKTGAAYL Sbjct 4481 LVCEGLSVTYRQLDEASNRLAHYLVDHGAGPGQTVALLFSRSAEAIASILAVLKTGAAYL 4540 Query 1571 PIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPA 1629 PIDP++P R+ FMLGDA PV AVTTA L R G+ + +IDV D + P T P+P Sbjct 4541 PIDPSSPDTRIEFMLGDAKPVVAVTTADLAGRFDGYGVAVIDVDDRRIDTQPETGLPLPT 4600 Query 1630 AVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIW 1689 +AY++YTSGTTG PKGV ITHRNVT+L SL A L AA VWS HS FD S WEI+ Sbjct 4601 PDGVAYLIYTSGTTGVPKGVAITHRNVTQLLGSLDAGLPAAGVWSHSHSLAFDVSVWEIF 4660 Query 1690 GALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGE 1749 GALL GGRLV+VPESVA SP D H LVA+ VSVLTQTP+AVAML +GLESV+LV+AGE Sbjct 4661 GALLRGGRLVVVPESVARSPQDLHDALVAQQVSVLTQTPSAVAMLSPEGLESVSLVMAGE 4720 Query 1750 ACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS---GMPPIGVPVSGAALFVLD 1806 ACPA +VD+WAPGRVM+NAYGPTETT+C ISAPL PGS G PIG PV+GAALFVLD Sbjct 4721 ACPAEVVDQWAPGRVMVNAYGPTETTMCVTISAPLAPGSAADGPVPIGSPVTGAALFVLD 4780 Query 1807 SWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD 1866 LRPVP GV GELY+AG+GV GY R LTASRFVACPFGG+G RMYRTGDLV W AD Sbjct 4781 ESLRPVPPGVVGELYVAGSGVAAGYVGRPDLTASRFVACPFGGAGTRMYRTGDLVRWNAD 4840 Query 1867 GQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIA 1926 GQL++ GR D+QVK+RGYRIELGE+ +ALA L GV QAVVIAREDR GDKRLVGY T Sbjct 4841 GQLQYFGRADEQVKVRGYRIELGEIQSALAGLDGVEQAVVIAREDRAGDKRLVGYVT--- 4897 Query 1927 PGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPA 1986 G+ D A R LA+RLP Y+VPAAV+ +DA+PLT NGKLD RALPAPEY YRAP Sbjct 4898 -GSADAAAARTALAERLPAYMVPAAVMTLDAMPLTANGKLDTRALPAPEY-TAGEYRAPE 4955 Query 1987 GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHAS 2046 P E+ +AGI+A +L +ERVGVDDSFF+LGGDS++AMR+IAAIN +L+A L VR + A Sbjct 4956 TPTEEILAGIYAEILDVERVGVDDSFFDLGGDSISAMRLIAAINASLDAGLAVRVVFEAP 5015 Query 2047 STRGLSQLLGRDA----------RPTSDPR---------LVSVHGDNPTEVHASDLTLDR 2087 + L+ +G RP P L + G +P A+ L LD Sbjct 5016 TVAQLAPRIGEGGTGLDPLTAGERPAVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDG 5075 Query 2088 FIDADTLATAVN 2099 +DA+ L A+ Sbjct 5076 RLDAEALGAALG 5087 Score = 1424 bits (3685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 829/1590 (53%), Positives = 1030/1590 (65%), Gaps = 76/1590 (4%) Query 474 WLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGI 533 +LV GA PG + + + I ++A G Y D + S T GD Sbjct 4503 YLVDHGAGPGQTVALLFSRSAEAIASILAVLKTGAAYLPIDPS---SPDTRIEFMLGDAK 4559 Query 534 LVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKT----AYIMPTSGTTGQPKL 589 V V A G+ VD+R + L T AY++ TSGTTG PK Sbjct 4560 PVVAVTTADLAGRFDGYGVAVIDVDDRRIDTQPETGLPLPTPDGVAYLIYTSGTTGVPKG 4619 Query 590 VRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAA 646 V I+H ++ ++ G A L D+SV EIFG G RLV S A Sbjct 4620 VAITHRNVTQLLGSLDA--GLPAAGVWSHSHSLAFDVSVWEIFGALLRGGRLVVVPESVA 4677 Query 647 MKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSA 706 DL D LVA++ +++ + +L +G ++++ +V+ GEA Sbjct 4678 RSPQDLH---DALVAQQVSVLTQTPSAVAMLSPEG--LESV------SLVMAGEACPAEV 4726 Query 707 VDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL-- 764 VD+W + G ++++YGPTE T+ T + + DG + +G P+ +F+ Sbjct 4727 VDQW-----APGRVMVNAYGPTETTMCVTISAPLAPGSAADGPV-PIGSPVTGAALFVLD 4780 Query 765 ---------AFGEVVIVGDLVADGYLG---IDGDGFGTVTAADGSRRRAFATGDRVTVDA 812 GE+ + G VA GY+G + F G+ R + TGD V +A Sbjct 4781 ESLRPVPPGVVGELYVAGSGVAAGYVGRPDLTASRF-VACPFGGAGTRMYRTGDLVRWNA 4839 Query 813 EGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQR 868 +G + GR D VK+ G R+++ E+ +A V V G V + + Sbjct 4840 DGQLQYFGRADEQVKVRGYRIELGEIQSALAGLDGVEQAVVIAREDRAGDKRLVGYVTGS 4899 Query 869 TREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNT 928 A A R+ +V V + +P NGK+D+ LP P+++A Sbjct 4900 ADAAAARTALAERLPAYMVPAAVMTL-----DAMPLTANGKLDTRALPA-PEYTAGEYRA 4953 Query 929 AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLI 987 ET L+ I++ L +G D S G S+ +R++ L L++ + Sbjct 4954 PETPTEEI-LAGIYAEILDVERVGVDDSFFDLGGDSISAMRLIAAINASLDAGLAVRVVF 5012 Query 988 GADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNM 1047 A T A LA P G PL A +RPA +PLSFAQ RLWFLDQLQ P+PVYNM Sbjct 5013 EAPTVAQLA-----PRIGEGGTGLDPLTAGERPAVVPLSFAQNRLWFLDQLQGPSPVYNM 5067 Query 1048 AVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDAT 1107 A ALRL G LD EALGAA+ DVV RHESLRT+F A +G P Q+VI +AD G +IVDA Sbjct 5068 AAALRLDGRLDAEALGAALGDVVARHESLRTLFAAPEGTPHQVVIPPDKADFGWEIVDAG 5127 Query 1108 AWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTA 1167 W A +L AI E AR++FDL+ +IPLR LFRI DD+HVLVAV HHIAADG S+ PL Sbjct 5128 GWSAGQLDEAIGETARYTFDLSAQIPLRAELFRIRDDQHVLVAVVHHIAADGMSITPLVR 5187 Query 1168 DLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMP 1227 DL AYA R AGR PDW PLPVQYVD+TLWQR GDLDD +S IAAQL+YWE+ALAGMP Sbjct 5188 DLGVAYAGRAAGRGPDWTPLPVQYVDFTLWQRAQFGDLDDGNSRIAAQLSYWEDALAGMP 5247 Query 1228 ERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKL 1287 ER++LPT RPYP VADQRGA++ +DWP +Q++V +ARQHNATSFMVV L VLLSKL Sbjct 5248 ERVQLPTDRPYPLVADQRGATVEIDWPTELQRRVGEVARQHNATSFMVVQTALTVLLSKL 5307 Query 1288 SGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVN---LAGDPSFAELLGQVRARSLAA 1344 +PDVAVGFPIAGR DPALD LVGFFVNTLVLRV+ L GDP+FAE+L QVR RSL+A Sbjct 5308 GANPDVAVGFPIAGRRDPALDELVGFFVNTLVLRVDLTELGGDPTFAEVLSQVRQRSLSA 5367 Query 1345 YENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPVGQLNLGDLQATPMPID 1398 YE+QDVPFEVLV+RL PTR+LTHHPL+QVMLAWQ+ P L+LGD+ TP+P+D Sbjct 5368 YEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGHDSGPAAGLSLGDVDVTPIPVD 5427 Query 1399 TRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPE 1458 T+TARMDL FS+ ER+++G EP GIGG VE+RTDVF+A +I LI+RLR+VL+A+ P Sbjct 5428 TQTARMDLTFSMGERWTDGGEPDGIGGTVEFRTDVFDAASIRALIDRLRRVLLAMTTDPA 5487 Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 R VSS+D LD E ARLDE GNRA +T AP S+P + AAQ AR P+A A+ C S+ Sbjct 5488 RAVSSVDLLDDAEHARLDEIGNRAAVTGSAPETDSVPALFAAQAARTPDAVALVCDGRSL 5547 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TYRELDE S+RLAH L GAGPG+ VALLF R A A+V+++AVLK+GAAYLPIDPA P Sbjct 5548 TYRELDEVSSRLAHCLVERGAGPGQIVALLFSRSAEAIVSILAVLKSGAAYLPIDPALPE 5607 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYIL 1637 R+ F+LGDA P+AA+TTA L R GH + +IDV D A+ P T P P +LAY++ Sbjct 5608 SRIGFLLGDAAPIAAITTAELTDRFDGHHVKVIDVNDPAIGDRPATALPAPGPEHLAYLI 5667 Query 1638 YTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGR 1697 YTSGTTG PKGV +THRNVT+L S + L VWSQ HS FD S WEI+GALL GGR Sbjct 5668 YTSGTTGVPKGVAVTHRNVTQLLTSGDSGLPRTGVWSQWHSLAFDVSVWEIFGALLHGGR 5727 Query 1698 LVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVD 1757 LV+VPESVA SP D H LLVAE VSVL+QTP+A L GL+SV LVVAGEACP+ LVD Sbjct 5728 LVVVPESVARSPEDLHALLVAEQVSVLSQTPSAAGALSPTGLDSVTLVVAGEACPSELVD 5787 Query 1758 RWAPGRVMLNAYGPTETTICAAISAPLRPGS-GMPPIGVPVSGAALFVLDSWLRPVPAGV 1816 RWAPGR M+NAYGPTE T+ AAISAPL GS G+ PIG PV GAA FVLD WLRPVP GV Sbjct 5788 RWAPGRAMINAYGPTEATVYAAISAPLGAGSPGVVPIGSPVPGAASFVLDEWLRPVPPGV 5847 Query 1817 AGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTD 1876 GELY+AGAGV GYW+R GLTA+RFVACPFG GARMYRTGDLV WRADGQL++LGR D Sbjct 5848 VGELYVAGAGVACGYWQRPGLTAARFVACPFGAPGARMYRTGDLVRWRADGQLDYLGRAD 5907 Query 1877 DQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLR 1936 +QVKIRGYRIELG+V ALA + GV QAVV+AREDRPGDKRLVGY T G DPA +R Sbjct 5908 EQVKIRGYRIELGDVRAALAWVDGVEQAVVVAREDRPGDKRLVGYVT----GTADPAAVR 5963 Query 1937 AQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGI 1996 A LA+RLPGY++P AVVV+ ALPLT NGKLD RALPAP+Y D + YRAP +E+ +AGI Sbjct 5964 AALAERLPGYMIPTAVVVMQALPLTPNGKLDTRALPAPDYQDADRYRAPDNAIEEILAGI 6023 Query 1997 FARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 FA+VLG+ERVGVDDSFF+LGGDS+++M+V+ Sbjct 6024 FAQVLGIERVGVDDSFFDLGGDSISSMQVV 6053 Score = 1357 bits (3513), Expect = 0.0, Method: Compositional matrix adjust. Identities = 719/1170 (62%), Positives = 860/1170 (74%), Gaps = 24/1170 (2%) Query 896 VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDS 954 +V + P +GK+D LP P++ A A + L I+++ LG +G D Sbjct 2808 IVALEEFPMTSSGKLDRKALPA-PEYQDADRYRAPSTAVEEILVGIYAQVLGLERVGVDD 2866 Query 955 SLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPL 1014 S G SL +R++ L L + + A T A LA + G DR PL Sbjct 2867 SFFDLGGDSLSAMRLIAAVNTSLNADLGVRAVFEAPTVAELALLTGS-----GGDRPEPL 2921 Query 1015 VAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHE 1074 VA +RPA IPLSFAQ RLWF+DQ Q P+P+YN+ VALRLRG LD +AL AA+ADVVGRHE Sbjct 2922 VAGERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLRGRLDADALAAALADVVGRHE 2981 Query 1075 SLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 SLRTVF + DGVP+Q+V+ A R CD++DA WP DRL+ + AAR++FDLA E PL Sbjct 2982 SLRTVFASADGVPQQVVVPAERIGFACDVIDARGWPEDRLREGMAAAARYTFDLANESPL 3041 Query 1135 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDY 1194 T LF +++ EH+LV HHIAADG S+AP DL AYASRCAG AP+WAPL VQYVDY Sbjct 3042 HTELFSVSEGEHMLVVAVHHIAADGMSIAPFARDLGIAYASRCAGEAPEWAPLAVQYVDY 3101 Query 1195 TLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP 1254 TLWQR LGD+DDSDS I AQL +W + LAG+PERL+LPT RPYP VAD RGA L VDWP Sbjct 3102 TLWQRAHLGDVDDSDSRIHAQLDFWADTLAGLPERLQLPTDRPYPQVADHRGARLAVDWP 3161 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFF 1314 A +QQQ+RR+AR+HNATSFMV+ A A LL+K+S S DVAVGFPIAGR +PALD L+GFF Sbjct 3162 AELQQQLRRVAREHNATSFMVIQAAFAALLAKMSASDDVAVGFPIAGRPEPALDELIGFF 3221 Query 1315 VNTLVLRVN---LAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 VNTLVLRV+ L GDP+FAELL QVR RSLAA+E+QDVPFE+LV+RL PTR+LTHHPLI Sbjct 3222 VNTLVLRVDLKELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSLTHHPLI 3281 Query 1372 QVMLAWQD------NPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGG 1425 QV+L W++ P L LGDLQ TPMP+ T TARMDL FSLAERF+E + AGI Sbjct 3282 QVLLGWENFPGEVSTPAAGLTLGDLQVTPMPVHTNTARMDLTFSLAERFTESGQRAGIAV 3341 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 EYRTDVF A ++ +IERL+++L AV A P R +SS+D LD E ARL EWGN+AVLT Sbjct 3342 TAEYRTDVFNADTVESMIERLQRLLTAVTAEPGRRLSSVDLLDSAEHARLAEWGNQAVLT 3401 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 A PV++ + AAQ AR P+A A+ SMTYR+LDEA+NRLAH L GAGPGE V Sbjct 3402 E-AMEPVTVAGLFAAQAARTPDAVALTFEGRSMTYRDLDEAANRLAHHLVDRGAGPGESV 3460 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+VA++AVLK+GAAYLPIDPA P RV FML DA P AAVTTA L R G Sbjct 3461 ALLFSRSADAIVAILAVLKSGAAYLPIDPALPATRVEFMLTDAGPTAAVTTAELADRFDG 3520 Query 1606 HDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLP 1664 DL ++DV D A+A P T PP PA +LA+I+YTSGTTG PKGV +T NV +LF L Sbjct 3521 FDLTVVDVADPAVATRPSTAPPAPAPTDLAHIIYTSGTTGVPKGVAVTQHNVAQLFDDLR 3580 Query 1665 A--RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 LSA QVW+Q HSY FD S WEIWGALL GGRLVIVPE+V+ SP +FH LLV E V+ Sbjct 3581 LGFALSAEQVWTQFHSYAFDFSVWEIWGALLHGGRLVIVPEAVSRSPEEFHTLLVREGVT 3640 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VLTQTP+AV +LPT GL++ +LV+ E CP LVDRWAPGRVM+N YGPTETT+ A S Sbjct 3641 VLTQTPSAVGLLPTDGLDATSLVIGAEPCPPELVDRWAPGRVMVNVYGPTETTMWACKST 3700 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PL+ GSG PPIG PV+ AA FVLD WLRPVPAGV GELY+AG GVGVGYWRR GLTASRF Sbjct 3701 PLQAGSGFPPIGSPVTRAAFFVLDEWLRPVPAGVVGELYLAGQGVGVGYWRRPGLTASRF 3760 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 +ACPFG G RMYRTGDLVCW DGQL + GR D+QVK+RGYRIELGE+ AL+ L GV Sbjct 3761 MACPFGEPGTRMYRTGDLVCWGPDGQLRYFGRADEQVKVRGYRIELGEIQAALSALDGVE 3820 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QAVV+AREDRPGDKRLVGY T G+ DP RA +A+RLP Y+VPAAVVV+DALP+TV Sbjct 3821 QAVVVAREDRPGDKRLVGYVT----GSADPGAARAAVAERLPAYMVPAAVVVLDALPVTV 3876 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAP+Y + YRAP+ VE+ +AGI+A+VLG+ERVGVDDSFF+LGGDSL+ Sbjct 3877 NGKLDARALPAPDYRAVDNYRAPSTAVEEILAGIYAQVLGVERVGVDDSFFDLGGDSLST 3936 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLS 2052 MR++ AIN L++DLPVR + A + L+ Sbjct 3937 MRLVTAINAALHSDLPVRVVFEAPTVAQLA 3966 Score = 836 bits (2159), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/1036 (50%), Positives = 635/1036 (62%), Gaps = 46/1036 (4%) Query 1032 LWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV 1091 L+ + Q +Y + + + G LD + L AV ++ RH +L F P Q++ Sbjct 6586 LFHANTAQATDDLYAGQLDISVTGPLDPDRLRDAVQAMIDRHPNLVARFCDRYDEPVQII 6645 Query 1092 IEARRADLGCDIVDATAWPADRLQR-AIEEAARHSFDLATEIPLRTWLFRIADDEHVLVA 1150 A +D A R+ R E A DLA + R L R A + + LV Sbjct 6646 PADPAAAWQYLELDGDADAEGRVARLCAAERAAVCGDLAEQPAFRVALARTAPERYRLVL 6705 Query 1151 VAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDS 1210 HHI DGWS+ L ++ A Y + R P AP Y + W L D Sbjct 6706 TNHHIVLDGWSMPILLGEIFAGYYGQ---RLPASAP----YRGFVDW----LAGRD---- 6750 Query 1211 PIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNA 1270 I A A W AG + L R + Q S + PA + Q V +AR + Sbjct 6751 -IDAARAAWAEVFAGF-DAPTLVGPRGRTELGPQGVESFAL--PAELSQAVTDLARARHT 6806 Query 1271 TSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPA----LDNLVGFFVNTLVLRVNLAG 1326 T V+ A A LL L+G DV G ++GR PA D +VG +NT+ +R N+ Sbjct 6807 TVNTVLQAAFAQLLCGLTGQSDVVFGTTVSGR--PAEVAGADTMVGLLINTVPVRANITA 6864 Query 1327 DPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLN 1386 + AELL Q++ ++Q + + R L + A+++ P+ Sbjct 6865 TTTTAELLDQLQGAYNHTLDHQHLALNEI------HRITGQDQLFDTLFAYENYPIDASA 6918 Query 1387 LGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERL 1446 L Q + + T+R + L + G E + VEY TDVF+A I LIERL Sbjct 6919 LSADQE--LAVTDITSRESTHYPLTVQAQPGEE---LRLQVEYDTDVFDAARIATLIERL 6973 Query 1447 RKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIP 1506 R++LV + P R +SSID LD E RLD WG+RAVL P T SIP + AAQ AR P Sbjct 6974 RRLLVVMTTDPARRLSSIDQLDDAEHDRLDAWGDRAVLAQPG-TSASIPALFAAQAARSP 7032 Query 1507 EAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTG 1566 A AV SM+YRELDE SNRLAH L G GPGE VALLF + A A+VA++AVLKTG Sbjct 7033 RAAAVTFEGRSMSYRELDEKSNRLAHLLIERGVGPGEAVALLFGKSADAIVAILAVLKTG 7092 Query 1567 AAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPP 1625 AAYLPIDPA P R+ FML D P+AA+T A L +L HDL +ID+ D A+A P T Sbjct 7093 AAYLPIDPALPAARIDFMLTDTAPMAAITVAALADKLDAHDLIVIDINDRAVARKPRTAL 7152 Query 1626 PMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLF--ASLPARLSAAQVWSQCHSYGFDA 1683 P PA ++A+I+YTSGTTG PKGV ++HRNVTRLF ++ LSA QVW+Q HSY FD Sbjct 7153 PAPAPEHVAHIIYTSGTTGVPKGVAVSHRNVTRLFDAQAVGVTLSADQVWTQFHSYAFDF 7212 Query 1684 SAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVA 1743 S WEIWGALL GGRLV+VP+SVA SP +FH LLVAE V+VL+QTP+AV ML QGLES A Sbjct 7213 SVWEIWGALLHGGRLVVVPDSVARSPMEFHALLVAEKVTVLSQTPSAVRMLSPQGLESAA 7272 Query 1744 LVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALF 1803 LV+ E CP LVDRWAPGR MLN YGPTE TI +++S PL GSG PPIG V GAALF Sbjct 7273 LVIGAEPCPPELVDRWAPGRTMLNVYGPTEATIFSSMSTPLAAGSGAPPIGSSVPGAALF 7332 Query 1804 VLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCW 1863 VLD WLRPV AGV GELY+AG GVG GY RR GLTA+RFV CPFG G+RMYRTGDLVCW Sbjct 7333 VLDGWLRPVAAGVVGELYVAGRGVGYGYVRRPGLTATRFVPCPFGEPGSRMYRTGDLVCW 7392 Query 1864 RADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYAT 1923 DGQL++ GR D+QVKIRGYRIE+GEV +ALA L GV QAVVIAREDRPGDKRLVGY Sbjct 7393 GPDGQLQYFGRADEQVKIRGYRIEVGEVRSALAALDGVEQAVVIAREDRPGDKRLVGYVI 7452 Query 1924 EIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYR 1983 G DPA R QLA RLPGY+VPAAVVV++ALP+T+NGKLD RALPAPEY GYR Sbjct 7453 ----GDADPAEARTQLADRLPGYMVPAAVVVLEALPMTLNGKLDIRALPAPEYS-AAGYR 7507 Query 1984 APAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALL 2043 +P P E+ +AGI+A VLG+ERVGVDDSFF+LGGDS++AMRVIAA+N+ ++ + VR + Sbjct 7508 SPTTPTEEILAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVIAAVNSAMDVGVAVRVIF 7567 Query 2044 HASSTRGLSQLLGRDA 2059 + + L+ +G D+ Sbjct 7568 ESPTVAQLAPRIGEDS 7583 Score = 806 bits (2081), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/1032 (50%), Positives = 634/1032 (62%), Gaps = 52/1032 (5%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV-IEARRADLGCD 1102 +Y + + L L G LD + L A+ VVGRH L F P Q++ + A + Sbjct 9154 LYVVQLDLTLTGPLDGDRLRDAMHAVVGRHPHLVARFCDQFDEPVQVIPADPAMAWRYLE 9213 Query 1103 IVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSV 1162 + P ++++R +DLA + +R L R DD H L+ HHI DGWSV Sbjct 9214 FKPNGSEPDEKIRRLCASERAAVYDLADQPAVRAALVRTGDDRHRLILTIHHIVLDGWSV 9273 Query 1163 APLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENA 1222 L + A Y + P P Y + W L D D + A A W Sbjct 9274 PILLNETFACYTGQRL-------PAPAPYRRFVTW----LADRD-----LDAARAAWGEL 9317 Query 1223 LAGMPERLRLPTARPYPPVADQRGASLVVDWPAS--VQQQVRRIARQHNATSFMVVAAGL 1280 LAG PT PP + GA V + S + + +AR + T V+ A Sbjct 9318 LAG----FDTPTLVG-PPQQRELGARGVQSFALSEDTTRALSELARSSHTTVSTVLQAAW 9372 Query 1281 AVLLSKLSGSPDVAVGFPIAGRSDPAL--DNLVGFFVNTLVLRVNLAGDPSFAELLGQVR 1338 A LL+ L+G DVA G ++GR + +++VG +NT+ +R ++ + ELLG+++ Sbjct 9373 AQLLAWLTGQHDVAFGTTVSGRPAEVVGAESMVGLMINTVPVRADMTAATTTTELLGRLQ 9432 Query 1339 ARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPID 1398 ++Q + + R H L + A+++ P L + M +D Sbjct 9433 RGHAETLDHQHLSLSEM------HRITGHEKLFDTLFAYENYP--------LDTSAMAVD 9478 Query 1399 TRTARMDLVFSLAERFSEGSEPA----GIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVA 1454 A D+ + + A +G VEY T VF+ ++ L +RL +VL+A+ Sbjct 9479 HELAIADVNMFERNHYPLTMQAALSGQELGLRVEYDTGVFDTPTVEALRDRLERVLLAMT 9538 Query 1455 AAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCG 1514 A P+R +S++D LD +E ARLDE NRA L P SIP + AQVA P+A A+ G Sbjct 9539 ADPDRPLSAVDLLDASEHARLDEIDNRAALARPRAALPSIPALFDAQVADRPDAVAINWG 9598 Query 1515 DASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDP 1574 SMTYRE+DE++NRLAH LA GAGPGE VALLF R A A+VA++AVLKTGAAYLPIDP Sbjct 9599 GTSMTYREVDESANRLAHLLAEQGAGPGESVALLFSRSAQAIVAILAVLKTGAAYLPIDP 9658 Query 1575 ANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVN-L 1633 A P R+ FML DA PVAAVTTAGLRSRL G L +ID+ D P A + + Sbjct 9659 AAPGARIRFMLDDAAPVAAVTTAGLRSRLNGSRLTVIDIEDPRIERQAATPLPAPAADGI 9718 Query 1634 AYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALL 1693 AY++YTSGTTG PKGV ITHRNVT+L SL A L VW+Q HSY FD S WEI+ LL Sbjct 9719 AYVIYTSGTTGVPKGVAITHRNVTQLLESLDAGLPRPGVWTQSHSYAFDVSVWEIFAPLL 9778 Query 1694 GGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPA 1753 GGRLV+VPESVA SP DFH LLV E V+VLTQTP+AVAML GLESV+LV+ GEACPA Sbjct 9779 RGGRLVVVPESVARSPKDFHALLVDEEVTVLTQTPSAVAMLSPDGLESVSLVMVGEACPA 9838 Query 1754 ALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVP 1813 +VDRWAPGRVM+NAYGPTETT+C AIS+PL GSG PPIG PV GAALFVLD WLRPV Sbjct 9839 DVVDRWAPGRVMVNAYGPTETTMCVAISSPLTRGSGAPPIGSPVDGAALFVLDPWLRPVA 9898 Query 1814 AGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLG 1873 GV GELY+AG GV GY R GLTASRFVACPFG GARMYRTGDLV WRADGQL++LG Sbjct 9899 PGVVGELYVAGDGVAAGYVGRPGLTASRFVACPFGAPGARMYRTGDLVRWRADGQLDYLG 9958 Query 1874 RTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPA 1933 R D+QVKIRGYRIELGEV ALA L V QAVVIARED+PG KRLVGY T G DP Sbjct 9959 RADEQVKIRGYRIELGEVQAALAALDDVDQAVVIAREDQPGVKRLVGYVT----GTADPG 10014 Query 1934 GLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNG-YRAPAGPVEKT 1992 R LA RLP Y+VPAAVV +D +PLT NGKLD RALPA +Y T G YRAP+ P E+ Sbjct 10015 EARTALAARLPVYMVPAAVVALDTIPLTPNGKLDTRALPAAQY--TGGAYRAPSTPTERA 10072 Query 1993 VAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 +A ++ARVLG ++VGVDDSFF+LGGDS++AMRV+AAIN L DL VR L A + + LS Sbjct 10073 LADVYARVLGTDQVGVDDSFFDLGGDSISAMRVVAAINAELGVDLAVRTLFDAPTVKELS 10132 Query 2053 QLLGRDARPTSD 2064 Q + +A T + Sbjct 10133 QRVRAEATDTDE 10144 Score = 801 bits (2069), Expect = 0.0, Method: Compositional matrix adjust. Identities = 488/1019 (48%), Positives = 612/1019 (61%), Gaps = 53/1019 (5%) Query 1025 LSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVD 1084 ++ Q +W Q + + V + + G +DT L A+ VV ESLR F VD Sbjct 1 MTRGQLDIWLAQQTGYFDVAWQLGVLVHIEGAIDTGLLHQAMRHVVNEAESLRASFFEVD 60 Query 1085 GVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADD 1144 G Q +E DL + + P +R RA + +++ T ++ LFR A D Sbjct 61 GQVFQKAVEYDDVDLVFYDLTESRDP-EREVRATASSIQNTPMPLTGPMIKFALFRTAPD 119 Query 1145 EHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGD 1204 E+ HHIA DG +A + ++A Y++ +G+ P+P + + + G+ Sbjct 120 EYYWFTTCHHIAIDGMGIALIGRRIAAVYSALASGK-----PIPPAF--FGSLHDLVSGE 172 Query 1205 LDDSDSP-IAAQLAYW-----ENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQ 1258 L+ SP YW E A P PY P S V SV Sbjct 173 LEYEASPKFVEDQEYWAAHRPEGDGADYPATAADDGRDPYSP-------SPPVQLDQSVV 225 Query 1259 QQVRRIARQHNATSFMVVAAGLAVLLSKLS--GSPDVAVGFPIAGRSDPALDNLVGFFVN 1316 +V+ +++ V+ A A+L+ S GS +V + FP++ R DP G Sbjct 226 GKVKELSKTLGIRRSSVLTAACALLVRGWSADGSDEVVLDFPVSRRPDPKSKTHPGMLAG 285 Query 1317 TLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVD-------RLKPTRALTHHP 1369 + L + A D +FA+ V RS A +Q P L R P R + + Sbjct 286 VVPLVLKAAPDTTFADFCRHVDTRSREALRHQQFPTRTLDGEGDFSGPRQAPNRVVVN-- 343 Query 1370 LIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 + L L+LGD+ AT +F L + G G Sbjct 344 FVPARLT--------LSLGDVPATAKYTSFGPVGHFGLFFLGFGDQQFLSTVGTG----- 390 Query 1430 RTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAP 1489 F + L ERL+++L A+AA P +SS+D L ERARL+E GNRAV + PA Sbjct 391 --QPFSNFDVSDLGERLQRILAAMAADPGLQLSSLDVLHPDERARLEEVGNRAVWSRPAS 448 Query 1490 TPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLF 1549 P+S+ + V R PE+ A+ C D SMTYRELDEA+NRLAH L G GAGPGE VALL Sbjct 449 APLSVAALFGTHVDRSPESVALVCADRSMTYRELDEAANRLAHLLIGQGAGPGEYVALLL 508 Query 1550 ERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLP 1609 R A A+V+++AVLKTGAAYLPI+PA+P R+ FML DA PVAA+TTA L RL GHD+ Sbjct 509 PRSAEAIVSIMAVLKTGAAYLPIEPASPDARIGFMLADANPVAAITTADLADRLDGHDMT 568 Query 1610 IIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS 1668 +IDV D + A PGTP P P +LAY++YTSGTTG PKGV IT+ NVT+L SL A L Sbjct 569 VIDVADPRIEAQPGTPLPAPDPADLAYLIYTSGTTGTPKGVAITNHNVTQLLESLDAGLP 628 Query 1669 AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 + VWSQ HSY FD S WEI+GALL GGRLV+VP+ VA SP D H LLV + V+V ++TP Sbjct 629 SPGVWSQSHSYAFDFSVWEIFGALLRGGRLVVVPDDVARSPEDLHDLLVEQGVTVYSETP 688 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 +AV M+ +GL+S ALV+ EACPA +VDRWAPGRVM+NAYGP+ETT+C AISAPLR S Sbjct 689 SAVQMVSPEGLDSTALVIGAEACPAEVVDRWAPGRVMVNAYGPSETTMCVAISAPLRAES 748 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 G PIG PV GAALFVLD WLRPVPAGV GELY+AG GV GY R GLTASRFVACPFG Sbjct 749 GAVPIGSPVPGAALFVLDGWLRPVPAGVVGELYVAGRGVAAGYVGRTGLTASRFVACPFG 808 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 G RMYRTGDLVCW DGQL +LGR D+QVKIRGYRIELGE+ ALA L GV AVVIA Sbjct 809 EPGERMYRTGDLVCWGDDGQLRYLGRADEQVKIRGYRIELGEIQAALAALDGVEAAVVIA 868 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 REDRPGDKRLVGY T GA DP RA LA RLP Y+VP+AVVV++ALPLTVNGKLD Sbjct 869 REDRPGDKRLVGYVT----GAADPVEARAALADRLPAYMVPSAVVVLEALPLTVNGKLDT 924 Query 1969 RALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 RALPAPEY T YRAP E+ +AGI+A VLG+ERV VD+SFFELGGDS+ +++V+A Sbjct 925 RALPAPEYS-TGEYRAPGNAFEEILAGIYAEVLGVERVSVDESFFELGGDSILSLQVVA 982 Score = 345 bits (886), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 326/931 (36%), Positives = 450/931 (49%), Gaps = 82/931 (8%) Query 1023 IPLSFAQRRLWFLDQL-QRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF- 1080 +PL+ Q+ L F Q +Y + + L G LD + L AV VV RH L +F Sbjct 1500 LPLTPLQQGLLFHSSTAQGSDDMYAVQLDFTLTGPLDPDRLRDAVHTVVNRHPHLAALFC 1559 Query 1081 ----PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRT 1136 V +P V+E R +LG I DA A + ++R DLA + R Sbjct 1560 EQYDEPVQIIPADPVVEWRYLELGG-IGDAEA--GELIERLCVSERAAVGDLAAQAAFRA 1616 Query 1137 WLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTL 1196 L R AD H V HHI DGWS+ L ++ +Y + P Y + Sbjct 1617 ALVRTADGRHRFVLTNHHILLDGWSLPILLREIFTSYYGQRL-------PAAGSYRAFLT 1669 Query 1197 WQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPP--VADQRGASLVVDWP 1254 W DLD + L ++ PE AR + V +Q A+L Sbjct 1670 WLAA--RDLDAAREAWGEVLHGFDTPTLVAPEGHLGQGARGFEKSCVPEQTTAALT---- 1723 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDN---LV 1311 +AR + T V+ A A++L+ L+G DV G P + +D+ +V Sbjct 1724 --------ELARSCHTTLSTVLQAAWALVLTSLTGQHDVVFGTPRSRVGQLEVDDAEQMV 1775 Query 1312 GFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLI 1371 G +NT+ +R ++ + A+LL Q++ A E+Q + + R H L Sbjct 1776 GLLINTVPVRADITATTTTADLLAQLQNSHNDALEHQHLALSEI------HRVTGHDQLF 1829 Query 1372 QVMLAWQDNPVGQ-LNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYR 1430 + +++ P+ + LG+ + I + R + L G E +G +E+ Sbjct 1830 DTLFVYENYPIDSGMTLGE---DGLAIAEFSNREYNHYPLTVEALPGRE---LGLHIEFD 1883 Query 1431 TDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPT 1490 TDVF+A AI L+ERL++VLVA+ A P R +SSID L +R + E + A ++AP Sbjct 1884 TDVFDAGAIRALVERLQRVLVAMTADPGRRLSSIDLLGRDDRELVLERLSGAGVSAPVGV 1943 Query 1491 PVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFE 1550 PQ+LAA VA +A AV G ++YRELDE S RLA +L G GP V + + Sbjct 1944 ---APQLLAAAVAADADAPAVVDGARELSYRELDEWSTRLARKLIDAGVGPERAVGVAVD 2000 Query 1551 RCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI 1610 RCA VVA AV+K G Y P+D +P R+A +L DAV V T G PI Sbjct 2001 RCAELVVAWWAVVKAGGIYAPVDLDHPVERIASVL-DAVDAVCVLTCGTDEVAGAGARPI 2059 Query 1611 --IDVVDALAAYPGTP-------PPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFA 1661 ID +D L+ Y P+ A + +Y+++TSG+TG PKGV ++H + A Sbjct 2060 VRIDGLD-LSGYSAREITDADRLSPLRAD-DTSYLIFTSGSTGVPKGVAVSHTGLLGWAA 2117 Query 1662 S---LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVA 1718 + L S A+V S FDAS E+ A G LV+ P V A + LL Sbjct 2118 AQRELFGLGSDARVL-MVASPTFDASVGELLLAAGSGAALVVAPPQVYAG-DALTALLQN 2175 Query 1719 EHVSVLTQTPAAVAMLPTQGLESV-ALVVAGEACPAALVDRWAPGRVMLNAYGPTETTI- 1776 + V+ TP V+ L L+++ LV GEAC LVD WAP R M N YGP+ETTI Sbjct 2176 QRVTAAILTPTVVSTLDRARLDALQTLVAVGEACLPELVDAWAPDRQMFNGYGPSETTIW 2235 Query 1777 --CAAISA--PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYW 1832 CA + A P+R IG P++G VLD WL PVP GV GELY++G +G GY Sbjct 2236 VTCARLHAGQPVR-------IGAPIAGVCARVLDGWLNPVPVGVVGELYLSGPALGHGYV 2288 Query 1833 RRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVA 1892 R LTA RFVA PFG G RMYRTGDLV W DG L++LGR D Q+K+RG RIELGE+ Sbjct 2289 GRVDLTAERFVANPFGEPGTRMYRTGDLVRWMPDGTLDYLGRADSQIKLRGQRIELGEIE 2348 Query 1893 TALAELAGVGQAVVIAREDRPGDKRLVGYAT 1923 L V QA V ++ G LV Y T Sbjct 2349 NTLLACPQVTQAAVTVQDGATG-SHLVAYVT 2378 Score = 145 bits (366), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 71/122 (59%), Positives = 95/122 (78%), Gaps = 0/122 (0%) Query 1935 LRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVA 1994 +R +L+ LP Y+VP +V ++ P+T +GKLD +ALPAPEY D + YRAP+ VE+ + Sbjct 2791 VRERLSAWLPEYMVPTHIVALEEFPMTSSGKLDRKALPAPEYQDADRYRAPSTAVEEILV 2850 Query 1995 GIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQL 2054 GI+A+VLGLERVGVDDSFF+LGGDSL+AMR+IAA+NT+LNADL VRA+ A + L+ L Sbjct 2851 GIYAQVLGLERVGVDDSFFDLGGDSLSAMRLIAAVNTSLNADLGVRAVFEAPTVAELALL 2910 Query 2055 LG 2056 G Sbjct 2911 TG 2912 Score = 112 bits (281), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 139/474 (30%), Positives = 208/474 (44%), Gaps = 56/474 (11%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V I+H ++ +++ G Q D+SV EIF Sbjct 9719 AYVIYTSGTTGVPKGVAITHRNVTQLLESLDA--GLPRPGVWTQSHSYAFDVSVWEIFAP 9776 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 G RLV S A D AL LV E T++ + +L DG ++++ Sbjct 9777 LLRGGRLVVVPESVARSPKDFHAL---LVDEEVTVLTQTPSAVAMLSPDG--LESV---- 9827 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQ------T 744 +V+ GEA VD+W + G ++++YGPTE T+ VA P+ + Sbjct 9828 --SLVMVGEACPADVVDRW-----APGRVMVNAYGPTETTMCVAISSPLTRGSGAPPIGS 9880 Query 745 TMDGALLRLG----RPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTA----ADG 796 +DGA L + RP+ P V GE+ + GD VA GY+G G A A G Sbjct 9881 PVDGAALFVLDPWLRPVAPGVV----GELYVAGDGVAAGYVGRPGLTASRFVACPFGAPG 9936 Query 797 SRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELH 856 +R + TGD V A+G + GR D VKI G R+++ EV +A V V Sbjct 9937 AR--MYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEVQAALAALDDVDQAVVIAR 9994 Query 857 SGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDS 912 G V + + GE A A R+ + +V VV + IP PNGK+D+ Sbjct 9995 EDQPGVKRLVGYVTGTADPGEARTALAARLPVYMVPAA-----VVALDTIPLTPNGKLDT 10049 Query 913 DNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGR-AIGPDSSLLGEGIGSLDLIRILP 971 LP Q++ T A L+ +++R LG +G D S G S+ +R++ Sbjct 10050 RALP-AAQYTGGAYRAPSTPTERA-LADVYARVLGTDQVGVDDSFFDLGGDSISAMRVVA 10107 Query 972 ETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPL 1025 LG L++ L A T L+ T D P+ ++ + +PL Sbjct 10108 AINAELGVDLAVRTLFDAPTVKELSQRVRA--EATDTDEVVPVQTLKQGSGVPL 10159 Score = 99.8 bits (247), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 206/798 (26%), Positives = 306/798 (39%), Gaps = 165/798 (20%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC--------------GYSVCDTADEIS 520 LV+RGA PG ++ + + I ++A +G G+ + D A + Sbjct 5563 LVERGAGPGQIVALLFSRSAEAIVSILAVLKSGAAYLPIDPALPESRIGFLLGDAAPIAA 5622 Query 521 VRTNAITEHGDGILVTVVDVA--------ATQLAVVGHDELRKVVDERVTQVTHDALLAT 572 + T +T+ DG V V+DV AT L G + L Sbjct 5623 ITTAELTDRFDGHHVKVIDVNDPAIGDRPATALPAPGPEHL------------------- 5663 Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDA----ISRAYGWGAHDTVLQCAPLTSDISV 628 AY++ TSGTTG PK V ++H ++ + + R W Q L D+SV Sbjct 5664 --AYLIYTSGTTGVPKGVAVTHRNVTQLLTSGDSGLPRTGVWS------QWHSLAFDVSV 5715 Query 629 EEIFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAI 684 EIFG G RLV S A DL AL LVA + +++ P+A L D++ Sbjct 5716 WEIFGALLHGGRLVVVPESVARSPEDLHAL---LVAEQVSVLSQTPSAAGALSPTGLDSV 5772 Query 685 DAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLP------ 738 +V+ GEA VD+W + G +++++YGPTEATV A Sbjct 5773 ---------TLVVAGEACPSELVDRW-----APGRAMINAYGPTEATVYAAISAPLGAGS 5818 Query 739 --IVCDQTTMDGA----LLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVT 792 +V + + GA L RP+ P V GE+ + G VA GY G Sbjct 5819 PGVVPIGSPVPGAASFVLDEWLRPVPPGVV----GELYVAGAGVACGYWQRPGLTAARFV 5874 Query 793 A----ADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAV 848 A A G+R + TGD V A+G + GR D VKI G R+++ +V +A V Sbjct 5875 ACPFGAPGAR--MYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGDVRAALAWVDGV 5932 Query 849 SDVAVELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPR 904 V G V + + AA A R+ ++ V V + +P Sbjct 5933 EQAVVVAREDRPGDKRLVGYVTGTADPAAVRAALAERLPGYMIPTAV-----VVMQALPL 5987 Query 905 KPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGS 963 PNGK+D+ LP P + A A L+ I+++ LG +G D S G S Sbjct 5988 TPNGKLDTRALPA-PDYQDADRYRAPDNAIEEILAGIFAQVLGIERVGVDDSFFDLGGDS 6046 Query 964 LDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTG--EDRFRPLVAAQRPA 1021 + ++++ R G D+ T A LA A DA + ++ P+ A P Sbjct 6047 ISSMQVVTRARA-AGLVCKTRDIFVEQTVARLARVAEVLDADSAVADEGLGPVQAT--PI 6103 Query 1022 AIPLSFAQRRLWFLDQL------QRPAPVYNMAVALRLRGYLDTEALGAAVAD------- 1068 L + +DQ Q PA V V L+ LD A+ D Sbjct 6104 IRWLQDVENAGGRVDQFNQAMLVQAPAAVTEADVVAVLQALLDRHAMLRLHVDRDAATGW 6163 Query 1069 --VVGRHESL--RTVFPAVDGVPRQLVIEAR-RADLGCDIVDATAWPADRLQRAIEEAAR 1123 V S+ R AVD + + VIEAR R + ++ + W Sbjct 6164 SLTVPEPGSVDARACLHAVDELSDEAVIEARSRLNPAAGVMLSAVW-------------- 6209 Query 1124 HSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPD 1183 A+ LV + HH+A DG S L DL+ A+A G+ Sbjct 6210 ------------------ANATRQLVVIVHHLAVDGVSWRILLQDLNIAWAQHHGGQP-- 6249 Query 1184 WAPLPVQYVDYTLWQREI 1201 LP + W + Sbjct 6250 -VTLPAAGTSFARWSERL 6266 Score = 85.5 bits (210), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 93/308 (31%), Positives = 137/308 (45%), Gaps = 36/308 (11%) Query 569 LLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISV 628 L A T+Y++ TSG+TG PK V +SH L + A +G G+ VL A T D SV Sbjct 2084 LRADDTSYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGSDARVLMVASPTFDASV 2143 Query 629 EEIFGGAACGARLVRS-AAMKTGD-LAALVDDLVARETTIVDLPTAVWQLLCADGDAIDA 686 E+ A GA LV + + GD L AL+ + R T + PT V L A DA Sbjct 2144 GELLLAAGSGAALVVAPPQVYAGDALTALLQN--QRVTAAILTPTVVSTLDRARLDA--- 2198 Query 687 IGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM 746 L+ +V GEA VD W + + + YGP+E T+ T + Q Sbjct 2199 -----LQTLVAVGEACLPELVDAW-----APDRQMFNGYGPSETTIWVTCARLHAGQP-- 2246 Query 747 DGALLRLGRPI-----------LPNTVFLAFGEVVIVGDLVADGYLG-IDGDGFGTVTAA 794 +R+G PI L GE+ + G + GY+G +D V Sbjct 2247 ----VRIGAPIAGVCARVLDGWLNPVPVGVVGELYLSGPALGHGYVGRVDLTAERFVANP 2302 Query 795 DGS-RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV 853 G R + TGD V +G + GR D+ +K+ G+R+++ E+ + P V+ AV Sbjct 2303 FGEPGTRMYRTGDLVRWMPDGTLDYLGRADSQIKLRGQRIELGEIENTLLACPQVTQAAV 2362 Query 854 ELHSGSLG 861 + G+ G Sbjct 2363 TVQDGATG 2370 Score = 85.1 bits (209), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 169/645 (27%), Positives = 245/645 (38%), Gaps = 101/645 (15%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V ++H ++A S G Q L D+SV EIFG Sbjct 8220 AYLIYTSGTTGVPKGVAVAHRNVAQLL--ASGESGLPHEGVWSQWHSLAFDVSVWEIFGA 8277 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 G RLV + D AL LVA T++ + +L +G A+ Sbjct 8278 LLQGGRLVVIPDAVVRSPEDFHAL---LVAEGVTVISQTPSAADVLSPEGLESAAL---- 8330 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF-LPIVCDQTTMDGAL 750 V+ GEA VD+W + G +++++YGPTEATV A P+ A Sbjct 8331 ----VVAGEACPAELVDRW-----APGRAMINAYGPTEATVYAAVSAPLQAGAAA--NAP 8379 Query 751 LRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYL---GIDGDGF-GTVTAAD 795 + +G P+ F+ GE+ + G VA GY + F A Sbjct 8380 VPIGSPVPGAAAFVLDEFLRPVPHGVVGELYVAGGGVAVGYWRRAELTASRFVACPFGAP 8439 Query 796 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL 855 G+R + TGD V ++G + GR D VKI G R+++ EV +A V V Sbjct 8440 GAR--MYRTGDLVRWGSDGQLQYLGRADEQVKIRGYRIELGEVRSALAALDGVEQAVVIA 8497 Query 856 HSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNL 915 G G TR+ L + V + VV + +P NGK+D L Sbjct 8498 REDRPGDKRLVGYITGGADPVEIRTRLADHLPAYMVPAA-VVTLEALPLTANGKLDVRAL 8556 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 P P++ A L+ I+++ LG +G D S G S+ ++++ R Sbjct 8557 PA-PEYRDVDRYRAPGSPVEETLAGIYAQVLGVDRVGIDDSFFDLGGDSISSMQVVTRAR 8615 Query 975 RYLGWRLSLLDLIGADTAANLADYAPTPDAP-------TGEDRFRPLVAAQRPAAIPL-S 1026 G L D+ T A LA A D G+ P++ R P+ Sbjct 8616 A-AGLVLRTRDIFTEQTVARLARVAGVTDGEYGVADEGVGDIAATPIIRWLRSVDGPVDQ 8674 Query 1027 FAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP----- 1081 F Q + L PA V V L+ LD A+ D SLR P Sbjct 8675 FNQTMV-----LAAPAGVTEADVVTVLQALLDRHAMLRLRVDDDSGEWSLRVPEPGSVDA 8729 Query 1082 -----AVDGVPRQLVIEAR-RADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 AVD + +IEAR R + ++ + W A Q Sbjct 8730 AQRVHAVDALSDAAIIEARSRLNPAAGVMLSALWVAATRQ-------------------- 8769 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGR 1180 LV + HH+A DG S L DL+ A+ G+ Sbjct 8770 ------------LVLIIHHLAVDGVSWRVLLEDLNIAWGQHHHGQ 8802 Score = 80.9 bits (198), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 125/484 (26%), Positives = 198/484 (41%), Gaps = 79/484 (16%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC--------------GYSVCDTADEIS 520 L+ +GA PG+ + + + I ++A G G+ + D + Sbjct 493 LIGQGAGPGEYVALLLPRSAEAIVSIMAVLKTGAAYLPIEPASPDARIGFMLADANPVAA 552 Query 521 VRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLA---TKTAYI 577 + T + + DG +TV+DVA D R+ L A AY+ Sbjct 553 ITTADLADRLDGHDMTVIDVA----------------DPRIEAQPGTPLPAPDPADLAYL 596 Query 578 MPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAAC 637 + TSGTTG PK V I++ ++ +++ G + Q D SV EIFG Sbjct 597 IYTSGTTGTPKGVAITNHNVTQLLESLDA--GLPSPGVWSQSHSYAFDFSVWEIFGALLR 654 Query 638 GARLVRSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRSRLRQIV 696 G RLV L D LV + T+ + P+AV Q++ +G +D+ +V Sbjct 655 GGRLVVVPDDVARSPEDLHDLLVEQGVTVYSETPSAV-QMVSPEG--LDSTA------LV 705 Query 697 IGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTTMDGALLRLGR 755 IG EA VD+W + G ++++YGP+E T+ VA P+ + + +G Sbjct 706 IGAEACPAEVVDRW-----APGRVMVNAYGPSETTMCVAISAPLRAESGAVP-----IGS 755 Query 756 PILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSR--RRAF 802 P+ +F+ GE+ + G VA GY+G G A R + Sbjct 756 PVPGAALFVLDGWLRPVPAGVVGELYVAGRGVAAGYVGRTGLTASRFVACPFGEPGERMY 815 Query 803 ATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG- 861 TGD V +G + GR D VKI G R+++ E+ +A V V G Sbjct 816 RTGDLVCWGDDGQLRYLGRADEQVKIRGYRIELGEIQAALAALDGVEAAVVIAREDRPGD 875 Query 862 ---VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRL 918 V + + E AA A R+ +V VV + +P NGK+D+ LP Sbjct 876 KRLVGYVTGAADPVEARAALADRLPAYMVPSA-----VVVLEALPLTVNGKLDTRALP-A 929 Query 919 PQWS 922 P++S Sbjct 930 PEYS 933 >gi|41407968|ref|NP_960804.1| hypothetical protein MAP1870c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396322|gb|AAS04187.1| hypothetical protein MAP_1870c [Mycobacterium avium subsp. paratuberculosis K-10] Length=1458 Score = 1419 bits (3673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 829/1435 (58%), Positives = 990/1435 (69%), Gaps = 66/1435 (4%) Query 659 LVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQG 718 LVA + +++ + L ADG ++++ +V+ GEA VD+W + G Sbjct 16 LVAEQVSVLTQTPSAVAALPADG--LESVA------LVVVGEACPVEVVDRW-----APG 62 Query 719 ISLLSSYGPTEATVVATFL----------PIVCDQTTMDGALL-RLGRPILPNTVFLAFG 767 ++++YGPTE T+ PI +T +L R RP P V G Sbjct 63 RVMVNAYGPTETTMCVAISAPLKPGSGVPPIGAPVSTAALFVLDRWLRPAPPGVV----G 118 Query 768 EVVIVGDLVADGYL---GIDGDGF-GTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKD 823 E+ + G VA GY G+ G F A G+R + TGD V A+G + GR D Sbjct 119 ELYVAGAGVAVGYTNRAGLTGSRFVACPFGAPGTR--MYRTGDLVRWRADGQLDYLGRAD 176 Query 824 AVVKISGKRVDIAEVTRRIAEDPAVSDVAV---ELHSGSLGVWFKSQRTREGEQDAAAAT 880 VKI G R+++ E+ + V AV E G + + G D A Sbjct 177 EQVKIRGYRIELGEIRSALVGLDGVEQAAVIAREDRPGDKRLVAYVTESATGTADPAE-I 235 Query 881 RIRLV--LVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGL 938 R RL L V + VV + +P NGK+D+ LP P + + + A + L Sbjct 236 RARLAQRLPEYMVPAAVVV-LETLPLTANGKLDTRALP-APGYQNSD-HRAPSSPVEEIL 292 Query 939 SQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLAD 997 + +++ LG +G D S G SL R++ L LS+ + A T + LA Sbjct 293 AGVFADVLGLDRVGVDDSFFDLGGDSLVATRLIAAIETTLNADLSVRAVFEAPTVSQLA- 351 Query 998 YAPTPDAPTGEDRFR--PLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRG 1055 G DR R PLVA +R A +PLSFAQ+RLWF+DQLQ P+P+YNMA ALRL G Sbjct 352 ------LCVGSDRGRREPLVAVERLAVVPLSFAQQRLWFIDQLQGPSPIYNMAAALRLTG 405 Query 1056 YLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQ 1115 LD +ALG A+ADVV R E+LRT+FPAVDG+P Q+VI A RAD G +VDAT WP DRLQ Sbjct 406 RLDADALGTALADVVARQETLRTLFPAVDGIPEQVVIPAERADFGWQVVDATGWPTDRLQ 465 Query 1116 RAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYAS 1175 +AIE RHSFDLATEIPLR LFRIADDEHVLVAV HHIAADG S+APL ADL AYAS Sbjct 466 QAIEATVRHSFDLATEIPLRARLFRIADDEHVLVAVLHHIAADGLSMAPLVADLGMAYAS 525 Query 1176 RCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTA 1235 RCAG AP WAPLPVQY DY+LWQR +LGD+ D++SP+AAQLAYWE LAG+PERL LPT Sbjct 526 RCAGHAPGWAPLPVQYADYSLWQRALLGDVADAESPMAAQLAYWEQQLAGLPERLALPTD 585 Query 1236 RPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAV 1295 RPYPPVAD RGAS++V+WP +QQ+VR +AR+HNATSFMV+ A LAVLL+KLS S D+A Sbjct 586 RPYPPVADYRGASVMVEWPTELQQRVRTVAREHNATSFMVIQAALAVLLAKLSASRDLAT 645 Query 1296 GFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVL 1355 GF IAGR +PALD LVGFFVNTLVLRV+LAGDPSF E L QVRARSLAAY++QDVPFEVL Sbjct 646 GFAIAGRREPALDELVGFFVNTLVLRVDLAGDPSFTESLAQVRARSLAAYDHQDVPFEVL 705 Query 1356 VDRLKPTRALTHHPLIQVMLAWQDN------PVGQLNLGDLQATPMPIDTRTARMDLVFS 1409 V+RL PTR+L HHPL+QV+LAWQ+ P G L LGDLQ TP+ DT+ ARMDL F+ Sbjct 706 VERLNPTRSLAHHPLVQVVLAWQNFAREDGVPAG-LALGDLQVTPLAADTQVARMDLTFT 764 Query 1410 LAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDG 1469 L ER++ EPAGIGG+VE+RTDVF+A+ I LI+RL +VL A+ A P + +SS+D +D Sbjct 765 LGERWTSAGEPAGIGGSVEFRTDVFDAERIPTLIQRLERVLAAMTADPGQRLSSVDLMDT 824 Query 1470 TERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNR 1529 E LDE GNR LT PA VSIP M A QV R P+A A C SMTYR+LDEASNR Sbjct 825 DEHIYLDEIGNREALTQPAAR-VSIPAMFADQVIRAPQAVATRCAGHSMTYRKLDEASNR 883 Query 1530 LAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAV 1589 LAH L GAGPGE VALLF R A AVVA++AVLKTGAAYLPIDPA+P R+ FM+ DA Sbjct 884 LAHLLIEAGAGPGESVALLFNRRAEAVVAVLAVLKTGAAYLPIDPAHPTARIEFMVADAA 943 Query 1590 PVAAVTTAGLRSRLAGHDLPIIDVVDA-LAAYPGTPPPMPAAVNLAYILYTSGTTGEPKG 1648 P+AA+TT L RL G LPIID+ D + +YP T P+P ++AY++YTSGTTG PKG Sbjct 944 PIAAITTTELAERLDGCGLPIIDIADPRIDSYPHTALPVPDPDDIAYLIYTSGTTGVPKG 1003 Query 1649 VGITHRNVTRLFASLPARLS-AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAA 1707 V ITH NVT L SL L+ QVWSQ HSY FD S WEI+GALL GGRLV+VPE VAA Sbjct 1004 VAITHNNVTELLGSLAPDLARPGQVWSQWHSYSFDISGWEIYGALLHGGRLVVVPEEVAA 1063 Query 1708 SPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLN 1767 SP+D H LL+ E V+VL QTP+A L QGLESV L+V GEACP+ LV+RW PGRVM+N Sbjct 1064 SPDDLHALLIDEKVTVLCQTPSAAGTLSPQGLESVTLLVGGEACPSELVERWGPGRVMIN 1123 Query 1768 AYGPTETTICAAISAPL---RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAG 1824 YGPTETT+ A+SAPL GS PIG PV GAA FVLD WLRPVPAGV GELY+AG Sbjct 1124 EYGPTETTMWVALSAPLTAGSTGSDAVPIGSPVPGAAFFVLDQWLRPVPAGVVGELYVAG 1183 Query 1825 AGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGY 1884 GVGVGY RRAGLTASRFVACPFG SG RMYRTGDLV W ADGQL +LGR D+QVKIRGY Sbjct 1184 TGVGVGYVRRAGLTASRFVACPFGESGTRMYRTGDLVRWGADGQLRYLGRADEQVKIRGY 1243 Query 1885 RIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLP 1944 RIELGE+ +ALA L G+ QA VIAREDRPGDKRLVGY TE GA DPA +RA+L QRLP Sbjct 1244 RIELGEIRSALAGLDGIEQAAVIAREDRPGDKRLVGYVTESVTGAADPADIRARLGQRLP 1303 Query 1945 GYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLE 2004 Y+VPAAVVV+DALPLTVNGKL+ RALPAPEY + Y APA P E+T+AGI+A+VLGLE Sbjct 1304 AYMVPAAVVVLDALPLTVNGKLNARALPAPEYIERERYCAPATPTEETLAGIYAQVLGLE 1363 Query 2005 RVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDA 2059 RVGVDDSFF+LGGDSL+AMRVIAAIN TL+A L VR L HA S RGL + LG+ A Sbjct 1364 RVGVDDSFFDLGGDSLSAMRVIAAINKTLDAGLAVRTLFHAPSVRGLCRQLGQGA 1418 Score = 518 bits (1334), Expect = 6e-144, Method: Compositional matrix adjust. Identities = 276/418 (67%), Positives = 316/418 (76%), Gaps = 22/418 (5%) Query 1701 VPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWA 1760 +PESV SP + HG+LVAE VSVLTQTP+AVA LP GLESVALVV GEACP +VDRWA Sbjct 1 MPESVTVSPQELHGMLVAEQVSVLTQTPSAVAALPADGLESVALVVVGEACPVEVVDRWA 60 Query 1761 PGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGEL 1820 PGRVM+NAYGPTETT+C AISAPL+PGSG+PPIG PVS AALFVLD WLRP P GV GEL Sbjct 61 PGRVMVNAYGPTETTMCVAISAPLKPGSGVPPIGAPVSTAALFVLDRWLRPAPPGVVGEL 120 Query 1821 YIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVK 1880 Y+AGAGV VGY RAGLT SRFVACPFG G RMYRTGDLV WRADGQL++LGR D+QVK Sbjct 121 YVAGAGVAVGYTNRAGLTGSRFVACPFGAPGTRMYRTGDLVRWRADGQLDYLGRADEQVK 180 Query 1881 IRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLA 1940 IRGYRIELGE+ +AL L GV QA VIAREDRPGDKRLV Y TE A G DPA +RA+LA Sbjct 181 IRGYRIELGEIRSALVGLDGVEQAAVIAREDRPGDKRLVAYVTESATGTADPAEIRARLA 240 Query 1941 QRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARV 2000 QRLP Y+VPAAVVV++ LPLT NGKLD RALPAP Y +++ +RAP+ PVE+ +AG+FA V Sbjct 241 QRLPEYMVPAAVVVLETLPLTANGKLDTRALPAPGYQNSD-HRAPSSPVEEILAGVFADV 299 Query 2001 LGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDAR 2060 LGL+RVGVDDSFF+LGGDSL A R+IAAI TTLNADL VRA+ A + L+ +G D R Sbjct 300 LGLDRVGVDDSFFDLGGDSLVATRLIAAIETTLNADLSVRAVFEAPTVSQLALCVGSD-R 358 Query 2061 PTSDP-----RLVSV---------------HGDNPTEVHASDLTLDRFIDADTLATAV 2098 +P RL V G +P A+ L L +DAD L TA+ Sbjct 359 GRREPLVAVERLAVVPLSFAQQRLWFIDQLQGPSPIYNMAAALRLTGRLDADALGTAL 416 Score = 93.2 bits (230), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 130/513 (26%), Positives = 208/513 (41%), Gaps = 66/513 (12%) Query 510 YSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDAL 569 + V D A ++ T + E DG + ++D+A D R+ H AL Sbjct 937 FMVADAAPIAAITTTELAERLDGCGLPIIDIA----------------DPRIDSYPHTAL 980 Query 570 LA---TKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDI 626 AY++ TSGTTG PK V I+H ++ +++ Q + DI Sbjct 981 PVPDPDDIAYLIYTSGTTGVPKGVAITHNNVTELLGSLAPDLARPGQ-VWSQWHSYSFDI 1039 Query 627 SVEEIFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDA 683 S EI+G G RLV A DL AL+ D + T + P+A L ++ Sbjct 1040 SGWEIYGALLHGGRLVVVPEEVAASPDDLHALLID--EKVTVLCQTPSAAGTLSPQGLES 1097 Query 684 IDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCD 742 + +++GGEA V++W G +++ YGPTE T+ VA P+ Sbjct 1098 V---------TLLVGGEACPSELVERW-----GPGRVMINEYGPTETTMWVALSAPLTAG 1143 Query 743 QTTMDGALLRLGRPILPNTVFLAF------------GEVVIVGDLVADGYL---GIDGDG 787 T D + +G P+ P F GE+ + G V GY+ G+ Sbjct 1144 STGSDA--VPIGSPV-PGAAFFVLDQWLRPVPAGVVGELYVAGTGVGVGYVRRAGLTASR 1200 Query 788 FGTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPA 847 F + S R + TGD V A+G + GR D VKI G R+++ E+ +A Sbjct 1201 FVACPFGE-SGTRMYRTGDLVRWGADGQLRYLGRADEQVKIRGYRIELGEIRSALAGLDG 1259 Query 848 VSDVAVELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIP 903 + AV G V + ++ A R+ L + V + VV + +P Sbjct 1260 IEQAAVIAREDRPGDKRLVGYVTESVTGAADPADIRARLGQRLPAYMVPAAVVV-LDALP 1318 Query 904 RKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIG 962 NGK+++ LP P++ A L+ I+++ LG +G D S G Sbjct 1319 LTVNGKLNARALP-APEYIERERYCAPATPTEETLAGIYAQVLGLERVGVDDSFFDLGGD 1377 Query 963 SLDLIRILPETRRYLGWRLSLLDLIGADTAANL 995 SL +R++ + L L++ L A + L Sbjct 1378 SLSAMRVIAAINKTLDAGLAVRTLFHAPSVRGL 1410 >gi|342859838|ref|ZP_08716491.1| hypothetical protein MCOL_13203 [Mycobacterium colombiense CECT 3035] gi|342132970|gb|EGT86190.1| hypothetical protein MCOL_13203 [Mycobacterium colombiense CECT 3035] Length=5964 Score = 1404 bits (3634), Expect = 0.0, Method: Compositional matrix adjust. Identities = 845/1607 (53%), Positives = 1033/1607 (65%), Gaps = 115/1607 (7%) Query 510 YSVCDTADEISVRTNAITE--HGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHD 567 + + D A ++ T + HG G+++ VD D V + Sbjct 4151 FLLADAAPVAAITTTELAHRLHGHGLMIVDVD------------------DPAVDRQPST 4192 Query 568 ALLA---TKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTS 624 ALLA AY++ TSGTTG PK V I+H +L ++++ G T QC P Sbjct 4193 ALLAPAPEDIAYLIYTSGTTGVPKGVAITHQNLTQQWESLNAGLPPGRVWT--QCHPYVF 4250 Query 625 DISVEEIFGGAACGARLVRSAAMKTG---DLAALVDDLVARETTIVDLPTAVWQLLCADG 681 D SV EI+G G RLV TG D AL+ + R + + P+AV L Sbjct 4251 DFSVWEIWGALLHGGRLVVVPEPVTGSPQDFHALL--IAERVSVLTQTPSAVAALPTEGL 4308 Query 682 DAIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF-LPIV 740 D++ +++GGEA VD+W + G ++++YGPTE TV A+ P+ Sbjct 4309 DSV---------ALLVGGEACAAEVVDRW-----APGRVMVNAYGPTEVTVYASMSAPLA 4354 Query 741 CDQTTMDGALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLG---IDGD 786 + +G P+ +F+ GE+ + G +A GY+G + G Sbjct 4355 AGSGAVP-----IGAPVPGAALFVLDGWLRPVPAGVVGELYVAGGGLACGYVGRAGLTGS 4409 Query 787 GF-GTVTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAED 845 F AA G +R + TGD V A+G + GR D VKI G RV++ E+ +A Sbjct 4410 RFVACPFAAPG--QRMYRTGDLVWWGADGQLRYVGRADEQVKIRGYRVELGEIQAALAAL 4467 Query 846 PAVSD---VAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNI 902 V +A E G + + G D AA + + + VV + + Sbjct 4468 DGVEQAVVIAREDRPGDKRLVAYVTESSTGTVDPAALRTQLVERLPEYMVPAAVVVLAAL 4527 Query 903 PRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGI 961 P NGK+D+ LP P + G A G L+ +++ LG +G D S G Sbjct 4528 PLTSNGKLDTRALPA-PGYQNGGYR-APAGPVEEILAGVFAEVLGLERVGVDDSFFDLGG 4585 Query 962 GSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGED--RFRPLVAAQR 1019 SL +R++ L LS+ + A T LA G D R PLVA +R Sbjct 4586 DSLLAMRLVAAIETGLDADLSVRTVFEAPTVTQLA-------LRVGADGGRREPLVAFER 4638 Query 1020 PAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTV 1079 PA +PLSFAQ+RLWF+DQL P+P+YNM ALRL G LD EALGAA+ADVV R ESLRTV Sbjct 4639 PAVVPLSFAQQRLWFIDQLLGPSPMYNMVAALRLSGSLDVEALGAALADVVARQESLRTV 4698 Query 1080 FPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLF 1139 FPAV+G+PRQ+VI + D G +VDAT W RL AI A RHSFDLATEIPLR LF Sbjct 4699 FPAVEGIPRQVVIPREQVDFGWQVVDATGWSEGRLGDAIGAAVRHSFDLATEIPLRVRLF 4758 Query 1140 RIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQR 1199 R+ADDEHVLVAV HHIA DG S+ PL +DL AYASRCAG AP WAPL VQY DYTLWQR Sbjct 4759 RVADDEHVLVAVVHHIAGDGLSMTPLVSDLGVAYASRCAGHAPGWAPLAVQYADYTLWQR 4818 Query 1200 EILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQ 1259 LGD+ D+DSPIAAQLAYWE LAG+PERL LPT RPYPPVAD RGA +VVDWPA +QQ Sbjct 4819 GQLGDVADADSPIAAQLAYWEQELAGLPERLALPTDRPYPPVADYRGAHVVVDWPAELQQ 4878 Query 1260 QVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLV 1319 Q+ R+AR+HNATSFMV+ A LAVLLSKLS S DVAVGFPIAGR DPALD LVG FVNTLV Sbjct 4879 QIARVAREHNATSFMVIQAALAVLLSKLSASNDVAVGFPIAGRGDPALDQLVGCFVNTLV 4938 Query 1320 LRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD 1379 LR+ +AGDP+ A+LL QVR RSLAAYE+QDVPFEVLV+RL PTRAL HHPL+QV+LAWQ Sbjct 4939 LRMQVAGDPTVAQLLAQVRQRSLAAYEHQDVPFEVLVERLNPTRALNHHPLVQVLLAWQ- 4997 Query 1380 NPVGQLN-------LGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTD 1432 N GQ N +GDLQ TP+ +TRTARMDL F+L E+++ EPAGIGG+VE+RTD Sbjct 4998 NFAGQDNDRVAGPAVGDLQVTPLSAETRTARMDLTFTLGEQWNAAGEPAGIGGSVEFRTD 5057 Query 1433 VFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPV 1492 VF+A I LI +L +VLVA+ A P R +SS+D LD E ARLDEWGNRA LT PA V Sbjct 5058 VFDAATIHALITKLERVLVAMTADPRRRLSSMDLLDAAEHARLDEWGNRAALTQPA-AAV 5116 Query 1493 SIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERC 1552 SIP AAQVAR PEA A+ C SMTYRELDEASNRLAH L+G G GPGE VALL R Sbjct 5117 SIPASFAAQVARTPEAAAISCAGRSMTYRELDEASNRLAHLLSGHGVGPGERVALLLSRS 5176 Query 1553 APAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIID 1612 A A+VA++AVLKTGAAYLPIDPA+P R+ F+L DA P+AA++TA L RL GHDL ++D Sbjct 5177 AEAIVAIMAVLKTGAAYLPIDPAHPDARIGFLLADAGPIAAISTAELAHRLDGHDLLVLD 5236 Query 1613 VVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS-AA 1670 V D A+ + P T P PAA +AY++YTSGTTG PKGV ITH NVT+L +L R+ A Sbjct 5237 VNDSAVDSQPSTALPAPAAEEIAYLIYTSGTTGVPKGVAITHHNVTQLLGALDVRMDLAG 5296 Query 1671 QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAA 1730 QVWSQ HS FD S E+WGALL GGRLV+ PESVA SP DFH LLVAE V+VL+QTP+A Sbjct 5297 QVWSQWHSLAFDVSVCEMWGALLYGGRLVVAPESVARSPEDFHALLVAEQVTVLSQTPSA 5356 Query 1731 VAMLPT---------QGLESVALVVAGEACPAALVDRW---APGRV-MLNAYGPTETTIC 1777 L T + L+ A+V AGEA + W PG + N YG TETT+ Sbjct 5357 FYALQTADALQPELGRQLKLEAVVFAGEALEPQRLGTWLHHHPGTPRLFNLYGTTETTVH 5416 Query 1778 AAISAPLR--PGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRA 1835 A+ + + P+GVP++ FVLD+ LRPVPAGV GELY+AG GVG+GY RA Sbjct 5417 ASFREIVHGDAENASSPVGVPLAHLGFFVLDASLRPVPAGVVGELYVAGTGVGIGYVGRA 5476 Query 1836 GLTASRFVACPFGGSGA---RMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVA 1892 LT SRFVACPFGG+GA RMYRTGDLV W DGQL +LGR D+QVKIRGYRIELGE+ Sbjct 5477 ALTGSRFVACPFGGAGAPGHRMYRTGDLVSWGTDGQLRYLGRADEQVKIRGYRIELGEIR 5536 Query 1893 TALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAV 1952 ALA L GV QAVVIAREDRPGDKRL+GY T G +PA R+ LA+RLP Y+VPAAV Sbjct 5537 AALAALDGVEQAVVIAREDRPGDKRLIGYIT----GTAEPAETRSGLAERLPAYMVPAAV 5592 Query 1953 VVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSF 2012 V +DALPLT NGKLD RALPAPEY + +GYRAPA E+ +AG++A VLGLERVGVDDSF Sbjct 5593 VALDALPLTANGKLDRRALPAPEYTEGDGYRAPATLTEEILAGVYADVLGLERVGVDDSF 5652 Query 2013 FELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDA 2059 F+LGGDSL+AMR+IAAIN +L+A+L VR L HA + R LS+ LG+DA Sbjct 5653 FDLGGDSLSAMRLIAAINASLDANLAVRTLFHAPTVRSLSRQLGQDA 5699 Score = 1391 bits (3601), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/1594 (53%), Positives = 1028/1594 (65%), Gaps = 96/1594 (6%) Query 510 YSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDAL 569 + + D A ++ T A+ E DG V V+DV + +L E + Sbjct 572 FLLADAAPVAAITTGALAERFDGRDVMVIDVDDPAVDAQPCTDLPAPAPEDI-------- 623 Query 570 LATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVE 629 AY++ TSGTTG PK V I+H +L ++++ G T QC P D SV Sbjct 624 -----AYLIYTSGTTGVPKGVAITHQNLTQQWESLNAGLPPGRVWT--QCHPYVFDFSVW 676 Query 630 EIFGGAACGARLVRSAAMKTG---DLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDA 686 EI+G G RLV TG D AL+ + R + + P+AV L D++ Sbjct 677 EIWGALLHGGRLVVVPEPVTGSPQDFHALL--IAERVSVLTQTPSAVAALPTEGLDSV-- 732 Query 687 IGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF-LPIVCDQTT 745 +++GGEA VD+W + G ++++YGPTE T+ A+ P+ Sbjct 733 -------ALLVGGEACAAEVVDRW-----APGRVMVNAYGPTEVTIYASMSAPLAAGSGA 780 Query 746 MDGALLRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLG---IDGDGF-GT 790 + +G P+ +F+ GE+ + G +A GY+G + G F Sbjct 781 VP-----IGAPVPGAALFVLDGWLRPVPAGVVGELYVAGGGLACGYVGRAGLTGSRFVAC 835 Query 791 VTAADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSD 850 AA G +R + TGD V A+G + GR D VKI G RV++ E+ +A V Sbjct 836 PFAAPG--QRMYRTGDLVWWGADGQLRYVGRADEQVKIRGYRVELGEIQAALAALDGVEQ 893 Query 851 ---VAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPN 907 +A E G + + G D AA + + + VV + +P N Sbjct 894 AVVIAREDRPGDKRLVAYVTESSTGTVDPAALRTQLVERLPEYMVPAAVVVLAALPLTSN 953 Query 908 GKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDL 966 GK+D+ LP P + G A G L+ +++ LG +G D S G SL Sbjct 954 GKLDTRALPA-PGYQNGGYR-APAGPVEEILAGVFAEVLGIERVGVDDSFFDLGGDSLLA 1011 Query 967 IRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLS 1026 +R++ L LS+ + A T LA + + G R PL+A QRPA +PLS Sbjct 1012 MRLVAAIETGLDADLSVRTVFEAPTVTQLAVHIGS-----GASRLEPLMAVQRPAVVPLS 1066 Query 1027 FAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGV 1086 FAQ+RLWF+DQLQ P+P+YNMA ALRL G LD EALGAA+ADVV RHESLRT+FPA +G+ Sbjct 1067 FAQQRLWFIDQLQGPSPMYNMAAALRLSGSLDIEALGAALADVVARHESLRTLFPAFEGI 1126 Query 1087 PRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEH 1146 P+Q+VI A RAD+ +VDA W RL AIE +A H+FDL TEIPL+T LFR+ADDEH Sbjct 1127 PQQVVIPADRADVDWQVVDACGWSESRLVEAIEASAVHTFDLTTEIPLQTRLFRVADDEH 1186 Query 1147 VLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLD 1206 VLVAV HHIA DG S+APL +DL AYASRCAG AP WAPL VQY DYTLWQR LGD+ Sbjct 1187 VLVAVVHHIAGDGLSIAPLVSDLGVAYASRCAGHAPGWAPLAVQYADYTLWQRGQLGDVA 1246 Query 1207 DSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIAR 1266 D+DSPIAAQLAYWE LAG+PERL LPT RPYPPVAD RGA + V+WPA +QQQ+ ++AR Sbjct 1247 DADSPIAAQLAYWEQELAGLPERLALPTDRPYPPVADYRGAHVAVEWPAELQQQIAQVAR 1306 Query 1267 QHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAG 1326 +HNATSFMV+ A LAVLLSKLS S DVAVGF IAGRSDPALD LVGFFVNTLVLRV+L G Sbjct 1307 EHNATSFMVIQAALAVLLSKLSASNDVAVGFAIAGRSDPALDELVGFFVNTLVLRVDLVG 1366 Query 1327 DPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD---NPVG 1383 DP+ A+LL QVR RSLAAYE+QDVPFEVLV+RL PTRAL HHPL+QVMLAWQ+ +P Sbjct 1367 DPTVAQLLAQVRQRSLAAYEHQDVPFEVLVERLNPTRALNHHPLVQVMLAWQNFAGDPAT 1426 Query 1384 QLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLI 1443 L LGDLQ +P+P+DTRTARMDL F+LAERF+E EPAGI G VE+RTDVF+A +I LI Sbjct 1427 SLALGDLQVSPVPVDTRTARMDLTFNLAERFTETGEPAGIAGDVEFRTDVFDAASIRALI 1486 Query 1444 ERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVA 1503 ERLR+VL A+ A R +SS+D +D E A LD+ GNRAVL PT SIP + AAQVA Sbjct 1487 ERLRRVLTAMTADQNRRLSSVDLMDAEEHAHLDKIGNRAVLARAVPTAASIPAVFAAQVA 1546 Query 1504 RIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVL 1563 R PEA A+ C SMTYRELD+ASNRLAH L GA PGECVALL R A AV+A++AVL Sbjct 1547 RTPEAAAITCAGRSMTYRELDKASNRLAHLLIALGARPGECVALLLPRSAEAVLAVMAVL 1606 Query 1564 KTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA-AYPG 1622 KTGAAYL IDPA+P R+ FM+ DA P+AA+TT L R GH LP+ID+ D P Sbjct 1607 KTGAAYLAIDPAHPTARMEFMVADAGPIAAITTVDLAERFDGHGLPVIDIEDPHPLGCPS 1666 Query 1623 TPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPA--RLSAAQVWSQCHSYG 1680 T P+PA +AY++YTSGTTG PKGV I H NVTRL +L A LSA QVW+QCHS Sbjct 1667 TDLPVPAPEEIAYLIYTSGTTGVPKGVAIPHHNVTRLLMALSADLELSAGQVWTQCHSLA 1726 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQG-- 1738 FD S WEI+GALL GGRLV+VPESV SP D H LL+AE VSVL+QTP+A L T G Sbjct 1727 FDYSVWEIFGALLHGGRLVVVPESVTRSPEDLHALLIAEQVSVLSQTPSAFYALQTAGAG 1786 Query 1739 -------LESVALVVAGEAC-PAAL---VDRWAPGRVMLNAYGPTETTICAAIS--APLR 1785 L+ +V GEA P L +DR ++N YG TETT+ A+ + Sbjct 1787 APEPGSQLQLETVVFGGEALEPQRLGPWLDRHRRSPRLINMYGITETTVHASFREISVAD 1846 Query 1786 PGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVAC 1845 + PIGVP+ FVLD+ LRPVP GV GELY+AG G+ GY RA LT SRFVAC Sbjct 1847 VDRSVSPIGVPLVHLGFFVLDASLRPVPPGVVGELYVAGGGLAYGYLGRAALTGSRFVAC 1906 Query 1846 PFGGS---GARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 PFGG+ G RMYRTGDLVCW ADGQL++LGR D+QVKIRGYRIELGE+ ALA L GV Sbjct 1907 PFGGAAAPGRRMYRTGDLVCWGADGQLDYLGRADEQVKIRGYRIELGEIRAALAALDGVE 1966 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QA VIAREDRPGDKRL+GY T GA DPA +RA+L QRLP Y+VPAAV+V+DALPLTV Sbjct 1967 QAAVIAREDRPGDKRLIGYIT----GAADPADVRARLGQRLPAYMVPAAVMVVDALPLTV 2022 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAPEY + +GYRAPA P E+ +AG++A VLGLERVGVDDSFF+LGGDSL+A Sbjct 2023 NGKLDTRALPAPEYTEGDGYRAPATPTEEILAGVYADVLGLERVGVDDSFFDLGGDSLSA 2082 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLG 2056 MRVIAAIN +L+A L VR + + + L+ +G Sbjct 2083 MRVIAAINKSLDAGLAVRTVFESPTVAQLAPRIG 2116 Score = 1356 bits (3509), Expect = 0.0, Method: Compositional matrix adjust. Identities = 746/1172 (64%), Positives = 870/1172 (75%), Gaps = 20/1172 (1%) Query 896 VVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDS 954 +V + P +GK+D LP P ++ +T + ++ I+++ LG +G D Sbjct 3466 IVVLDEFPLTSSGKLDRKALPE-PVFATTSFRAPQT-ETEKTVAGIYAKVLGIDKVGVDD 3523 Query 955 SLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPL 1014 S G SL +R++ L LS+ + A T A LA P G PL Sbjct 3524 SFFDLGGDSLSAMRLIAAVNTALDADLSVRAVFEAPTVAQLA-----PRIGQGGG-LEPL 3577 Query 1015 VAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHE 1074 V +RP +PLSFAQ RLWF+DQLQ P+P+YN+ V LRL G LD +ALGAA++DVVGRHE Sbjct 3578 VPVERPPVVPLSFAQSRLWFIDQLQGPSPLYNVVVPLRLSGRLDADALGAALSDVVGRHE 3637 Query 1075 SLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPL 1134 SLRT+FPA++G+P+Q+VI A RAD+G D++DAT WPADRL+ AI A RH FDLATEIPL Sbjct 3638 SLRTLFPAIEGIPQQVVIPAERADVGWDVIDATGWPADRLEEAIGAAVRHRFDLATEIPL 3697 Query 1135 RTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDY 1194 R WLFR+AD EHV+VAV H IAADGWS L D+S AY SRCAGRAPDWAPLPVQYVDY Sbjct 3698 RAWLFRVADGEHVMVAVVHEIAADGWSTTRLVRDMSVAYTSRCAGRAPDWAPLPVQYVDY 3757 Query 1195 TLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWP 1254 TLWQR GDLDD DS IAAQLAYWE LAGMPERL+LPT RPYPPVAD RGA + ++WP Sbjct 3758 TLWQRAQFGDLDDKDSRIAAQLAYWERTLAGMPERLQLPTDRPYPPVADHRGARVTLEWP 3817 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFF 1314 A +QQQV R+AR+HNAT FMV A LAVLL+KLS S DVAVGFPIAGR DPALD LVGFF Sbjct 3818 AQLQQQVARVAREHNATGFMVTQAALAVLLAKLSASSDVAVGFPIAGRRDPALDELVGFF 3877 Query 1315 VNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVM 1374 VNTLVLRV+L GDP+ AELL QVRAR LAAYE+QDVPFEVLV+RL P R+L HHPLIQV+ Sbjct 3878 VNTLVLRVDLTGDPTVAELLAQVRARGLAAYEHQDVPFEVLVERLNPARSLAHHPLIQVV 3937 Query 1375 LAWQDNPVGQLN-------LGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAV 1427 AW + P GQ+N L DLQ TP+ DT+TA+MD+VF L ER++E EPAGI G V Sbjct 3938 FAWNNFP-GQVNDSATGLSLNDLQVTPLTGDTQTAKMDVVFFLKERWTEAGEPAGISGTV 3996 Query 1428 EYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAP 1487 E+RTDVF+ + I ++ERL +VL A+ A P R +SS+D LD E ARLDE GNRA L+ P Sbjct 3997 EFRTDVFDTETIQAMVERLERVLGAMTADPTRRLSSVDLLDACEHARLDEIGNRAALSRP 4056 Query 1488 APTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVAL 1547 A VSIP + AAQVAR PEA AV G +TYRELDEASNRLAH LA G G CVAL Sbjct 4057 A-AAVSIPALFAAQVARAPEAVAVTFGSRCVTYRELDEASNRLAHLLADRRVGAGACVAL 4115 Query 1548 LFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHD 1607 LF R AVVAM+AVLK GAAYLPIDPA P R+ F+L DA PVAA+TT L RL GH Sbjct 4116 LFSRSVDAVVAMLAVLKAGAAYLPIDPAAPAERIEFLLADAAPVAAITTTELAHRLHGHG 4175 Query 1608 LPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPAR 1666 L I+DV D A+ P T PA ++AY++YTSGTTG PKGV ITH+N+T+ + SL A Sbjct 4176 LMIVDVDDPAVDRQPSTALLAPAPEDIAYLIYTSGTTGVPKGVAITHQNLTQQWESLNAG 4235 Query 1667 LSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQ 1726 L +VW+QCH Y FD S WEIWGALL GGRLV+VPE V SP DFH LL+AE VSVLTQ Sbjct 4236 LPPGRVWTQCHPYVFDFSVWEIWGALLHGGRLVVVPEPVTGSPQDFHALLIAERVSVLTQ 4295 Query 1727 TPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRP 1786 TP+AVA LPT+GL+SVAL+V GEAC A +VDRWAPGRVM+NAYGPTE T+ A++SAPL Sbjct 4296 TPSAVAALPTEGLDSVALLVGGEACAAEVVDRWAPGRVMVNAYGPTEVTVYASMSAPLAA 4355 Query 1787 GSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACP 1846 GSG PIG PV GAALFVLD WLRPVPAGV GELY+AG G+ GY RAGLT SRFVACP Sbjct 4356 GSGAVPIGAPVPGAALFVLDGWLRPVPAGVVGELYVAGGGLACGYVGRAGLTGSRFVACP 4415 Query 1847 FGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVV 1906 F G RMYRTGDLV W ADGQL ++GR D+QVKIRGYR+ELGE+ ALA L GV QAVV Sbjct 4416 FAAPGQRMYRTGDLVWWGADGQLRYVGRADEQVKIRGYRVELGEIQAALAALDGVEQAVV 4475 Query 1907 IAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKL 1966 IAREDRPGDKRLV Y TE + G VDPA LR QL +RLP Y+VPAAVVV+ ALPLT NGKL Sbjct 4476 IAREDRPGDKRLVAYVTESSTGTVDPAALRTQLVERLPEYMVPAAVVVLAALPLTSNGKL 4535 Query 1967 DHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVI 2026 D RALPAP Y GYRAPAGPVE+ +AG+FA VLGLERVGVDDSFF+LGGDSL AMR++ Sbjct 4536 DTRALPAPGY-QNGGYRAPAGPVEEILAGVFAEVLGLERVGVDDSFFDLGGDSLLAMRLV 4594 Query 2027 AAINTTLNADLPVRALLHASSTRGLSQLLGRD 2058 AAI T L+ADL VR + A + L+ +G D Sbjct 4595 AAIETGLDADLSVRTVFEAPTVTQLALRVGAD 4626 Score = 812 bits (2098), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/1057 (49%), Positives = 635/1057 (61%), Gaps = 51/1057 (4%) Query 1023 IPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPA 1082 PL+ Q +W + R + + LR+ G +D L + VV E LR F Sbjct 23 FPLTRGQLDIWLAQETDREGARWQLGYLLRIEGTVDPWLLEQTIRQVVREAEPLRAAFFQ 82 Query 1083 VDGVPRQLVIEARRADLGCDIVDATAWPADRL--QRAIEEAARHSFDLA-TEIPLRTWLF 1139 VDG Q ++ +L C RL Q ++EA R + + T +PL LF Sbjct 83 VDGQVFQKAVDYPDVELAC---------YQRLGSQDPVQEAYRLASSIQRTVMPLSGPLF 133 Query 1140 RIA-----DDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYV-- 1192 + A DE L HHI ADG +A + + Y++ +G AP+P + Sbjct 134 KFALLQTRADEFYLFVCCHHIVADGIGLALVCHRIGDVYSALASG-----APIPPVFFGS 188 Query 1193 --DYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPE-RLRLPTARPYPPVADQRG--- 1246 D + E +S + AYW L E R RL P AD+R Sbjct 189 LSDLIACESEY-----ESSTDYLEDQAYWAKNLPTETEPRYRLA------PAADERDPYE 237 Query 1247 ASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLS-GSPDVAVGFPIAGRSDP 1305 +S V++ ++ +++ V+AA A+L+ S +V FP++ R P Sbjct 238 SSPPVEFDPVTVAGIQELSQALGVRRSSVIAAACALLVGGCDVSSSEVVFEFPVSRRVRP 297 Query 1306 ALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRAL 1365 + G + L + + + + A V R A +Q P L ++ Sbjct 298 EAQTVPGMVTGYVPLVLKASAESTVASFCEHVDTRLREALHHQRFPVHALENKRLRGSVQ 357 Query 1366 THHPLIQVMLAWQD--NPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGI 1423 T + +I + + N VG G L T + ID +D FS +R G +P Sbjct 358 TSNRIILNFIPTTNLANIVGAEVSGTLTHTNL-IDQFG--LDF-FSDHDRLLLGVQPGAT 413 Query 1424 GGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAV 1483 + + L+ERL +VL A+ A P R +SS D L G ERARLDE GNRA Sbjct 414 TSGLVGSRQWLSGCDVRDLVERLERVLGAMTADPTRRLSSADLLGGGERARLDEIGNRAA 473 Query 1484 LTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGE 1543 L+ PA VSIP + AAQVAR PEA AV G +TYRELDEASNRLAH LA G G Sbjct 474 LSRPAAA-VSIPALFAAQVARAPEAVAVTFGSRCVTYRELDEASNRLAHLLADRRVGAGA 532 Query 1544 CVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRL 1603 CVALLF R AVVAM+AVLK GAAYLPIDPA P R+ F+L DA PVAA+TT L R Sbjct 533 CVALLFSRSVDAVVAMLAVLKAGAAYLPIDPAAPAERIEFLLADAAPVAAITTGALAERF 592 Query 1604 AGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFAS 1662 G D+ +IDV D A+ A P T P PA ++AY++YTSGTTG PKGV ITH+N+T+ + S Sbjct 593 DGRDVMVIDVDDPAVDAQPCTDLPAPAPEDIAYLIYTSGTTGVPKGVAITHQNLTQQWES 652 Query 1663 LPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVS 1722 L A L +VW+QCH Y FD S WEIWGALL GGRLV+VPE V SP DFH LL+AE VS Sbjct 653 LNAGLPPGRVWTQCHPYVFDFSVWEIWGALLHGGRLVVVPEPVTGSPQDFHALLIAERVS 712 Query 1723 VLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISA 1782 VLTQTP+AVA LPT+GL+SVAL+V GEAC A +VDRWAPGRVM+NAYGPTE TI A++SA Sbjct 713 VLTQTPSAVAALPTEGLDSVALLVGGEACAAEVVDRWAPGRVMVNAYGPTEVTIYASMSA 772 Query 1783 PLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF 1842 PL GSG PIG PV GAALFVLD WLRPVPAGV GELY+AG G+ GY RAGLT SRF Sbjct 773 PLAAGSGAVPIGAPVPGAALFVLDGWLRPVPAGVVGELYVAGGGLACGYVGRAGLTGSRF 832 Query 1843 VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 VACPF G RMYRTGDLV W ADGQL ++GR D+QVKIRGYR+ELGE+ ALA L GV Sbjct 833 VACPFAAPGQRMYRTGDLVWWGADGQLRYVGRADEQVKIRGYRVELGEIQAALAALDGVE 892 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 QAVVIAREDRPGDKRLV Y TE + G VDPA LR QL +RLP Y+VPAAVVV+ ALPLT Sbjct 893 QAVVIAREDRPGDKRLVAYVTESSTGTVDPAALRTQLVERLPEYMVPAAVVVLAALPLTS 952 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAP Y GYRAPAGPVE+ +AG+FA VLG+ERVGVDDSFF+LGGDSL A Sbjct 953 NGKLDTRALPAPGY-QNGGYRAPAGPVEEILAGVFAEVLGIERVGVDDSFFDLGGDSLLA 1011 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDA 2059 MR++AAI T L+ADL VR + A + L+ +G A Sbjct 1012 MRLVAAIETGLDADLSVRTVFEAPTVTQLAVHIGSGA 1048 Score = 682 bits (1759), Expect = 0.0, Method: Compositional matrix adjust. Identities = 531/1400 (38%), Positives = 712/1400 (51%), Gaps = 88/1400 (6%) Query 573 KTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIF 632 + AY++ TSGTTG PK V I H ++ A+S A QC L D SV EIF Sbjct 1676 EIAYLIYTSGTTGVPKGVAIPHHNVTRLLMALSADLELSAGQVWTQCHSLAFDYSVWEIF 1735 Query 633 GGAACGARLV---RSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIG 688 G G RLV S DL AL L+A + +++ P+A + L A A + Sbjct 1736 GALLHGGRLVVVPESVTRSPEDLHAL---LIAEQVSVLSQTPSAFYALQTAGAGAPEPGS 1792 Query 689 RSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPI-VCDQTTMD 747 + +L +V GGEA+ + WL+ + L++ YG TE TV A+F I V D +D Sbjct 1793 QLQLETVVFGGEALEPQRLGPWLDRH-RRSPRLINMYGITETTVHASFREISVAD---VD 1848 Query 748 GALLRLGRPILPNTVFLAFGEVV-----IVGDLVADGYL---------GIDGDGFGTVT- 792 ++ +G P++ F+ + +VG+L G + G F Sbjct 1849 RSVSPIGVPLVHLGFFVLDASLRPVPPGVVGELYVAGGGLAYGYLGRAALTGSRFVACPF 1908 Query 793 -AADGSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDV 851 A RR + TGD V A+G + GR D VKI G R+++ E+ +A V Sbjct 1909 GGAAAPGRRMYRTGDLVCWGADGQLDYLGRADEQVKIRGYRIELGEIRAALAALDGVEQA 1968 Query 852 AVELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPN 907 AV G + + + + A R+ +V V + V +P N Sbjct 1969 AVIAREDRPGDKRLIGYITGAADPADVRARLGQRLPAYMVPAAV-----MVVDALPLTVN 2023 Query 908 GKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDL 966 GK+D+ LP P+++ A L+ +++ LG +G D S G SL Sbjct 2024 GKLDTRALPA-PEYTEGDGYRAPATPTEEILAGVYADVLGLERVGVDDSFFDLGGDSLSA 2082 Query 967 IRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLS 1026 +R++ + L L++ + + T A LA P G +PLVA RPA +PLS Sbjct 2083 MRVIAAINKSLDAGLAVRTVFESPTVAQLA-----PRIGGGGATRKPLVAGARPAGVPLS 2137 Query 1027 FAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGV 1086 +AQ RLWFLD+ + YNM A R+ G LD EAL AA+ DV+ RHE+LRT+FP VDGV Sbjct 2138 YAQSRLWFLDRFEGGVATYNMPTAFRISGALDVEALTAAIDDVIARHEALRTIFPDVDGV 2197 Query 1087 PRQLVIEA-----RRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRI 1141 P Q V+ A RR D +V T D L + A + FDLATEIP+R ++ + Sbjct 2198 PFQQVVPAEAGMWRRGD--AAVVSLTE--RDVLGELVALAG-YRFDLATEIPIRAQIYAV 2252 Query 1142 ADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREI 1201 ++HV+ V HHIA DGWS+AP+ D+ AY +R GRAP APLPVQY DYTLWQRE Sbjct 2253 GPEQHVVGIVVHHIAFDGWSLAPMARDIGEAYRARRQGRAPQLAPLPVQYADYTLWQRES 2312 Query 1202 LGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQV 1261 LG D DS IA QLAYW LA +PE + LP R PPV RG ++ + + + Sbjct 2313 LGVESDPDSVIAGQLAYWRQELADLPEVVSLPPDRARPPVPSYRGDAVDMQLDPRLWAGI 2372 Query 1262 RRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLR 1321 + +A HNAT+ MV+ A + V L + DV +G PIAGR D ALD LVGFFVNT VLR Sbjct 2373 KALAAAHNATASMVLQAAMVVALHRAGAGEDVTMGTPIAGRMDAALDELVGFFVNTWVLR 2432 Query 1322 VNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNP 1381 V + F+++L VR ++L AY NQDVPFE LV++L P R+ HHP+ QV LA+Q+N Sbjct 2433 VAVTPAHRFSDVLACVRQKALDAYSNQDVPFERLVEQLNPVRSTAHHPVFQVALAFQNNV 2492 Query 1382 VGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDV 1441 ++ L L P+ +D+RTA+ DL L E S G V Y TD+++ ++ Sbjct 2493 RPEVALDGLGVEPLAVDSRTAKFDLDVDLREVPSADPTAPMAAGVVTYATDLYDRATVER 2552 Query 1442 LIERLRKVLVAVAAAPERTVSSIDALDGTER-ARLDEWGNRAVLTAPAPTPVSIPQMLAA 1500 + +V+ V A V + LD ER L W V AP+ V+ + AA Sbjct 2553 FVTWFGRVIEGVVADASVVVGDLALLDDGERDLVLSRWSGAGV---GAPSGVAPELLAAA 2609 Query 1501 QVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMV 1560 A V S+TY ELD S RLA L G GP V + R VVA Sbjct 2610 VAADPDAVAIVDRAQ-SLTYGELDRWSTRLARVLIEAGVGPESAVGVAMGRSTELVVAWW 2668 Query 1561 AVLKTGAAYLPIDPANPPPRVAFMLG--DAVPVA---AVTTAGLRSR---------LAGH 1606 AV K G Y+P+DPA+P R+A +L DA+ V A T AG R+R L G Sbjct 2669 AVQKAGGVYVPVDPAHPVERIATVLDSVDALCVLTRDADTVAGARTRPVLRIDGLDLYGR 2728 Query 1607 DLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPA- 1665 I D LAA N AY+++TSG+TG PKGV +TH + + A+ Sbjct 2729 CAEAITDTDRLAAL--------GPDNTAYVIFTSGSTGTPKGVAVTHGGLPGVAAAHREV 2780 Query 1666 -RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL 1724 L A S FDA+ E+ A+ G LV+ P V A LL + V+ Sbjct 2781 FGLGADTRMLAVLSPTFDAALGELLVAVGSRGALVVAPPEVYAG-EALTALLQEQRVTAA 2839 Query 1725 TQTPAAVAMLPTQGLESVA-LVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAP 1783 TP ++ L L+ ++ L+V GEACP LV WAPGR M N YGPTETTI A +AP Sbjct 2840 VMTPTLLSSLDRTRLDELSTLIVGGEACPDELVTAWAPGRRMFNGYGPTETTIWAT-TAP 2898 Query 1784 LRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFV 1843 L G + IG P+ G VLD+ L P P GV GELY+ G V GY R LTA RFV Sbjct 2899 LLAGQPV-RIGTPLPGIRALVLDARLNPAPIGVVGELYLGGPAVACGYLGRPDLTAERFV 2957 Query 1844 ACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQ 1903 A P+G +GAR+YRTGDLV W G L++LGR D Q+K+RG+RIELGEV L V + Sbjct 2958 ADPYGPAGARLYRTGDLVRWTLGGTLDYLGRADAQIKLRGHRIELGEVENTLLGCPQVAR 3017 Query 1904 AVVIAREDRPGDKRLVGYAT 1923 A RE G LV Y T Sbjct 3018 AAATVREGGAG-SHLVAYVT 3036 Score = 139 bits (350), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 70/123 (57%), Positives = 94/123 (77%), Gaps = 1/123 (0%) Query 1935 LRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVA 1994 +R QL+ LP Y+VPA +VV+D PLT +GKLD +ALP P + T +RAP EKTVA Sbjct 3449 VRQQLSAWLPEYMVPAHIVVLDEFPLTSSGKLDRKALPEPVFA-TTSFRAPQTETEKTVA 3507 Query 1995 GIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQL 2054 GI+A+VLG+++VGVDDSFF+LGGDSL+AMR+IAA+NT L+ADL VRA+ A + L+ Sbjct 3508 GIYAKVLGIDKVGVDDSFFDLGGDSLSAMRLIAAVNTALDADLSVRAVFEAPTVAQLAPR 3567 Query 2055 LGR 2057 +G+ Sbjct 3568 IGQ 3570 >gi|118468008|ref|YP_884815.1| linear gramicidin synthetase subunit D [Mycobacterium smegmatis str. MC2 155] gi|46810981|gb|AAT01807.1| non-ribosomal peptide synthetase [Mycobacterium smegmatis str. MC2 155] gi|118169295|gb|ABK70191.1| linear gramicidin synthetase subunit D [Mycobacterium smegmatis str. MC2 155] Length=2559 Score = 1396 bits (3613), Expect = 0.0, Method: Compositional matrix adjust. Identities = 812/1513 (54%), Positives = 1002/1513 (67%), Gaps = 69/1513 (4%) Query 1023 IPLSFAQRRLWFLDQLQRPA--PVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F R VY + + + + G LD L AV VV RH +L F Sbjct 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 Query 1081 PAVDGVPRQL-----VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+ +I R DL D D T P +++ DL R Sbjct 1153 VEQFGEPVQVLTADPMIAWRYLDLRGD--DLT--PDHEIEQLCAAERSAVCDLLERPTFR 1208 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R + ++H V HHI DGWS+ L ++ A Y R P AP Y ++ Sbjct 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFV 1261 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRG-ASLVVDWP 1254 W L D+ A A W L G PT P V RG S V Sbjct 1262 NW-------LATQDA--TAAKAAWREVLDG----FETPTLVAPPGVPGPRGIESYRVS-- 1306 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNLVG 1312 A + + +AR + T V+ A LL +++G DVA G ++GR +D A +++VG Sbjct 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 1366 Query 1313 FFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT-HHPLI 1371 +NT+ +R ++ D + +LL R L ++ N + E L L ++ H L Sbjct 1367 LLINTVPIRAKVSADTTVGDLL-----RQLQSHHNDTLEHEHLA--LNDIHHVSGHEQLF 1419 Query 1372 QVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRT 1431 + ++ P+ +Q + + R + L+ G E +G VEY T Sbjct 1420 DTLFLYESYPIDTSAFMGVQE--LAVTEFNNREYNHYPLSVMALPGHE---LGLRVEYDT 1474 Query 1432 DVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTP 1491 VF+ I+ LI+R +++L A+ P R +SS+D +D ER +LDEW NRAVLT P +P Sbjct 1475 SVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSP 1534 Query 1492 VSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFER 1551 SIP++ A QV R PEA AV S+ Y ELDEA+N+LA+ LA GA PG+ VAL+ R Sbjct 1535 QSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPR 1594 Query 1552 CAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPII 1611 A A+VA++AVLKTGAAYLPIDP+ P R+ FMLGDA PVAAVTT LRSR G DL ++ Sbjct 1595 SADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVV 1654 Query 1612 DVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA 1670 +V D A+ YP T P+ ++AY++YTSGTTG PKGV ITH NVT++ +LPA L A Sbjct 1655 EVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAG 1714 Query 1671 --QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 VWSQ HS FD S WEIWGALL GGRLVIVPES+A SP+D H LLV+E V+VL QTP Sbjct 1715 PGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTP 1774 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 +AV M+ +GLE ALVVAGEACP +VDRWA RVM+NAYGPTE+TI AAISAPL PGS Sbjct 1775 SAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGS 1834 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 + PIG PV A FVLD WLRPVP GV GELY+AG GVGVGY R+GLT +RFVACPFG Sbjct 1835 DVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFG 1894 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 GARMYRTGDLV W DGQL++LGR D+QVKIRGYRIELGE+ AL+++ GV QAVVIA Sbjct 1895 EPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 1954 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 REDRPGDKRLVGY T G DPA R++L RLP Y+VPAAVV ++ LPLTVNGKLD Sbjct 1955 REDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDR 2010 Query 1969 RALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAA 2028 RALPAPEY YRAP EKT+AGIFA VLG+ER+G+DDSFF+LGGDS++AMRV AA Sbjct 2011 RALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERIGLDDSFFDLGGDSISAMRVTAA 2070 Query 2029 INTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDP-RLVSVHGDNPTEVHASDLTLDR 2087 +NT L+ADL VR L A + LS + DA +D +VHG + TEVHA DLTLD+ Sbjct 2071 VNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDK 2130 Query 2088 FIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRL-DVDGRLICLVRAESD 2146 FIDA TL TA LP P ++TVLLTGATGFLGRYL+LE LR+L VD ++ICLVR +SD Sbjct 2131 FIDAPTLRTATTLPRPDGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSD 2190 Query 2147 EDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIV 2206 EDARRRLE TFD+ DP L +HF ELA +RL+VVAGDK +P+LGLD+ W+RLAE+VDLIV Sbjct 2191 EDARRRLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIV 2249 Query 2207 DSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDAD 2265 DSAA VN+ PY ELFGPNV GTAELIR ALT+KLKPF +VST+DVG IEPS FTE AD Sbjct 2250 DSAAFVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQAD 2309 Query 2266 IRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNM 2325 IR++S TR ++ G+A GYG SKWAGEVLLREA+D C LPVAVFR GMI+ D +YAGQLN+ Sbjct 2310 IRLVSATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNV 2369 Query 2326 SDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVA----G 2381 +D V+RMVLS++ATG+AP SFY+ G RQRAHFDGLPV FVA+AI LG +VA Sbjct 2370 TDTVSRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTD 2429 Query 2382 SSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQR 2441 S+ +GF TYHVMNPHDDGIG+D Y+DWLIEAGYPI RI+DF EWLQRFEA+L L D+QR Sbjct 2430 STASGFETYHVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQR 2489 Query 2442 RHSVLPM--LLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTI 2499 ++SVL M LL + LQP PTRG AP DRF+AAVR A +G + +IPHV+ I Sbjct 2490 QNSVLQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEG---EIPHVTREVI 2546 Query 2500 INYVTNLQLLGLL 2512 + YVT+LQLLGLL Sbjct 2547 VKYVTDLQLLGLL 2559 Score = 719 bits (1856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/573 (65%), Positives = 433/573 (76%), Gaps = 8/573 (1%) Query 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 RT+ S D LD E +++ WGNRAVLT P PTPV+IP + A QV R P+A A+ GD S Sbjct 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 Query 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 TYRELDEASNRLAH LA GA PG VA L R A++++++VLKTGAAYLP+DPA+P Sbjct 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 Query 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYIL 1637 R+ FM+ DA PVAA+TTA LRSRL +DL +ID+ D A+ P P +LAY+ Sbjct 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMT 187 Query 1638 YTSGTTGEPKGVGITHRNVTRLFASLPARLSAA--QVWSQCHSYGFDASAWEIWGALLGG 1695 YTSGTTG PK V +TH NVT+L ++L A L + QVWSQ HS FD S WEIWGALL G Sbjct 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHG 247 Query 1696 GRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAAL 1755 GRLV+VPESV +SP+D H LL+ E VSVL QTP+A ML +GLES L+VAGEACP L Sbjct 248 GRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEACPTEL 307 Query 1756 VDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAG 1815 VDRWAPGRVM+NAYGPTE TI AA+S PL G+G+ PIG PV GAALFVLD WLRP P G Sbjct 308 VDRWAPGRVMINAYGPTEATIYAAMSEPLTAGTGVAPIGAPVPGAALFVLDKWLRPAPEG 367 Query 1816 VAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRT 1875 V GELY+AG GV GY R LTASRFVACPFG +G RMYRTGDLV W +DGQLE+LGR Sbjct 368 VVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRA 427 Query 1876 DDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGL 1935 D+QVKIRGYRIELGE+ ALA+L GV QAVVIAREDRPGDKRLVGY T G DPA L Sbjct 428 DEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQL 483 Query 1936 RAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEY-GDTNGYRAPAGPVEKTVA 1994 R LA+ LP Y+VP AVVV+D +PLTVNGKLD RALPAPEY N YRAP+ P E+ +A Sbjct 484 RTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILA 543 Query 1995 GIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 ++A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 544 DVYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 576 Score = 95.5 bits (236), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 199/805 (25%), Positives = 308/805 (39%), Gaps = 148/805 (18%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY+ TSGTTG PK V ++H ++ A+ G Q L D+SV EI+G Sbjct 184 AYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGA 243 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 G RLV S DL L+ + + + + P+A +L +G Sbjct 244 LLHGGRLVVVPESVGSSPDDLHNLL--ITEKVSVLCQTPSAA-GMLSPEG--------LE 292 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALL 751 +++ GEA VD+W + G ++++YGPTEAT+ A + + T + Sbjct 293 STTLIVAGEACPTELVDRW-----APGRVMINAYGPTEATIYAA----MSEPLTAGTGVA 343 Query 752 RLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLG---IDGDGFGTVTAADGS 797 +G P+ +F+ GE+ + G VA GY+G + F + + Sbjct 344 PIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE-T 402 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 R + TGD V ++G + GR D VKI G R+++ E+ +A+ V V Sbjct 403 GERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIARE 462 Query 858 GSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD 913 G V + + + A A + +V VV + IP NGK+D Sbjct 463 DRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTA-----VVVLDTIPLTVNGKLDRR 517 Query 914 NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPE 972 LP SAA A + L+ ++++ LG +G D S G S+ ++++ Sbjct 518 ALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR 577 Query 973 TRRYLGWRLSLLDLIGADTA------------ANLADYAPTP-------------DAPTG 1007 R G + D+ T +++ D P D PTG Sbjct 578 ARA-AGIQCRPRDIFVEQTVAGVARVAVAAGESHVVDEGVGPVVATPIMRWLREVDGPTG 636 Query 1008 EDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLR---GYLDTEALGA 1064 + F V Q PA + L L L R A LRLR DT+ Sbjct 637 Q--FNQTVITQAPAGVTEDDVVVILQAL--LDRHA-------TLRLRVEDTQEDTDEWSL 685 Query 1065 AV--ADVVGRHESLRTVFPAVDGVPRQLVIEAR-RADLGCDIVDATAWPADRLQRAIEEA 1121 V A VG E LRT VD + +++EAR R D + + W + Q Sbjct 686 LVPEAGAVGARECLRT----VDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ------ 735 Query 1122 ARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRA 1181 LV + HH+A DG S L DL+ A+A C G++ Sbjct 736 --------------------------LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS 769 Query 1182 PDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPP- 1240 + LP + W +L + +D+ LA A+ +P+ LP +P Sbjct 770 IE---LPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQ--ALPPVQPDTDT 821 Query 1241 --VADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFP 1298 A Q ASL V+ + +V R ++VA GLA ++ D +G Sbjct 822 YVTAGQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLA--WTEFLNRSDTPIGVD 878 Query 1299 IAGR-------SDPALDNLVGFFVN 1316 + G SD L VG+F Sbjct 879 VEGHGRYDELASDVDLSRTVGWFTT 903 Score = 82.4 bits (202), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 121/453 (27%), Positives = 185/453 (41%), Gaps = 67/453 (14%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V I+HG++ D + G Q L D+SV EI+G Sbjct 1678 AYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGA 1737 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRS 690 G RLV S A DL AL LV+ ++ P+AV +++ +G A Sbjct 1738 LLHGGRLVIVPESIAGSPDDLHAL---LVSEGVNVLYQTPSAV-RMMSPEGLEGTA---- 1789 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGAL 750 +V+ GEA VD+W ++++YGPTE+T+ A Sbjct 1790 ----LVVAGEACPTEVVDRWAVDRV-----MINAYGPTESTIYAA--------------- 1825 Query 751 LRLGRPILPNTVFLAFGEVVIVG-DLVADGYL-----GIDGDGF----------GTVTAA 794 + P+ P + + G V G V D +L G+ G+ + + Sbjct 1826 --ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGL 1883 Query 795 DGSR----------RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAE 844 G+R R + TGD V +G + GR D VKI G R+++ E+ +++ Sbjct 1884 TGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSD 1943 Query 845 DPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPR 904 V V G AAA + + L + V + VV + +P Sbjct 1944 VDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPA-AVVTLETLPL 2002 Query 905 KPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGS 963 NGK+D LP P++ +A A + L+ I++ LG IG D S G S Sbjct 2003 TVNGKLDRRALPA-PEYQSAQRYRAPETETEKTLAGIFAHVLGVERIGLDDSFFDLGGDS 2061 Query 964 LDLIRILPETRRYLGWRLSLLDLIGADTAANLA 996 + +R+ L LS+ L A T A L+ Sbjct 2062 ISAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 >gi|5869932|emb|CAB55600.1| peptide synthetase [Mycobacterium smegmatis] Length=5990 Score = 1393 bits (3605), Expect = 0.0, Method: Compositional matrix adjust. Identities = 812/1513 (54%), Positives = 1002/1513 (67%), Gaps = 69/1513 (4%) Query 1023 IPLSFAQRRLWFLDQLQRPA--PVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q+ L F R VY + + + + G LD L AV VV RH +L F Sbjct 4524 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 4583 Query 1081 PAVDGVPRQL-----VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 G P Q+ +I R DL D D T P +++ DL R Sbjct 4584 VEQFGEPVQVLTADPMIAWRYLDLRGD--DLT--PDHEIEQLCAAERSAVCDLLERPTFR 4639 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R + ++H V HHI DGWS+ L ++ A Y R P AP Y ++ Sbjct 4640 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFV 4692 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRG-ASLVVDWP 1254 W L D+ A A W L G PT P V RG S V Sbjct 4693 NW-------LATQDATAAK--AAWREVLDG----FETPTLVAPPGVPGPRGIESYRVS-- 4737 Query 1255 ASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNLVG 1312 A + + +AR + T V+ A LL +++G DVA G ++GR +D A +++VG Sbjct 4738 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 4797 Query 1313 FFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT-HHPLI 1371 +NT+ +R ++ D + +LL R L ++ N + E L L ++ H L Sbjct 4798 LLINTVPIRAKVSADTTVGDLL-----RQLQSHHNDTLEHEHLA--LNDIHHVSGHEQLF 4850 Query 1372 QVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRT 1431 + ++ P+ +Q + + R + L+ G E +G VEY T Sbjct 4851 DTLFLYESYPIDTSAFMGVQE--LAVTEFNNREYNHYPLSVMALPGHE---LGLRVEYDT 4905 Query 1432 DVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTP 1491 VF+ I+ LI+R +++L A+ P R +SS+D +D ER +LDEW NRAVLT P +P Sbjct 4906 SVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSP 4965 Query 1492 VSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFER 1551 SIP++ A QV R PEA AV S+ Y ELDEA+N+LA+ LA GA PG+ VAL+ R Sbjct 4966 QSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPR 5025 Query 1552 CAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPII 1611 A A+VA++AVLKTGAAYLPIDP+ P R+ FMLGDA PVAAVTT LRSR G DL ++ Sbjct 5026 SADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVV 5085 Query 1612 DVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA 1670 +V D A+ YP T P+ ++AY++YTSGTTG PKGV ITH NVT++ +LPA L A Sbjct 5086 EVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAG 5145 Query 1671 --QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTP 1728 VWSQ HS FD S WEIWGALL GGRLVIVPES+A SP+D H LLV+E V+VL QTP Sbjct 5146 PGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTP 5205 Query 1729 AAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS 1788 +AV M+ +GLE ALVVAGEACP +VDRWA RVM+NAYGPTE+TI AAISAPL PGS Sbjct 5206 SAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGS 5265 Query 1789 GMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFG 1848 + PIG PV A FVLD WLRPVP GV GELY+AG GVGVGY R+GLT +RFVACPFG Sbjct 5266 DVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFG 5325 Query 1849 GSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIA 1908 GARMYRTGDLV W DGQL++LGR D+QVKIRGYRIELGE+ AL+++ GV QAVVIA Sbjct 5326 EPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 5385 Query 1909 REDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH 1968 REDRPGDKRLVGY T G DPA R++L RLP Y+VPAAVV ++ LPLTVNGKLD Sbjct 5386 REDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDR 5441 Query 1969 RALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAA 2028 RALPAPEY YRAP EKT+AGIFA VLG+ER+G+DDSFF+LGGDS++AMRV AA Sbjct 5442 RALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERIGLDDSFFDLGGDSISAMRVTAA 5501 Query 2029 INTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDP-RLVSVHGDNPTEVHASDLTLDR 2087 +NT L+ADL VR L A + LS + DA +D +VHG + TEVHA DLTLD+ Sbjct 5502 VNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDK 5561 Query 2088 FIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRL-DVDGRLICLVRAESD 2146 FIDA TL TA LP P ++TVLLTGATGFLGRYL+LE LR+L VD ++ICLVR +SD Sbjct 5562 FIDAPTLRTATTLPRPDGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSD 5621 Query 2147 EDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIV 2206 EDARRRLE TFD+ DP L +HF ELA +RL+VVAGDK +P+LGLD+ W+RLAE+VDLIV Sbjct 5622 EDARRRLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIV 5680 Query 2207 DSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDAD 2265 DSAA VN+ PY ELFGPNV GTAELIR ALT+KLKPF +VST+DVG IEPS FTE AD Sbjct 5681 DSAAFVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQAD 5740 Query 2266 IRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNM 2325 IR++S TR ++ G+A GYG SKWAGEVLLREA+D C LPVAVFR GMI+ D +YAGQLN+ Sbjct 5741 IRLVSATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNV 5800 Query 2326 SDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVA----G 2381 +D V+RMVLS++ATG+AP SFY+ G RQRAHFDGLPV FVA+AI LG +VA Sbjct 5801 TDTVSRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTD 5860 Query 2382 SSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQR 2441 S+ +GF TYHVMNPHDDGIG+D Y+DWLIEAGYPI RI+DF EWLQRFEA+L L D+QR Sbjct 5861 STASGFETYHVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQR 5920 Query 2442 RHSVLPM--LLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTI 2499 ++SVL M LL + LQP PTRG AP DRF+AAVR A +G + +IPHV+ I Sbjct 5921 QNSVLQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEG---EIPHVTREVI 5977 Query 2500 INYVTNLQLLGLL 2512 + YVT+LQLLGLL Sbjct 5978 VKYVTDLQLLGLL 5990 Score = 814 bits (2102), Expect = 0.0, Method: Compositional matrix adjust. Identities = 486/1024 (48%), Positives = 620/1024 (61%), Gaps = 56/1024 (5%) Query 1023 IPLSFAQRRLWFLDQL-QRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 +PL+ Q L F L Q +Y + + + + G LD E + AV V+ R ++ F Sbjct 3021 LPLTPLQHGLLFHTGLSQDSEDLYAVQLDISVSGRLDVERMRDAVQTVITRRPNVVAHFY 3080 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHS--FDLATEIPLRTWLF 1139 G P Q++ +L VD + Q A AA + L + P R + Sbjct 3081 EDFGEPVQIL--PANPELAWQYVDLSGRSDIDAQIAQISAAERAAVCRLGDQPPFRAAVL 3138 Query 1140 RIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQR 1199 R ++ + V HHI DGWS L ++ +Y + P PV Y + W Sbjct 3139 RTGEETYRFVLTNHHIVLDGWSKPILLQEIFVSYFGQRL-------PAPVPYRRFVSWLA 3191 Query 1200 EILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQ 1259 E D+D+ AA W +G PT P +A R A A Q Sbjct 3192 E-----QDNDAARAA----WRGVFSG----FETPTLVGTPGLALGRRAVESFQVSAETTQ 3238 Query 1260 QVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNT 1317 + +AR + T V+ A +L L+G PDVA G ++GR P D++VG +NT Sbjct 3239 ALGELARSCHTTVSTVLQGAWAQVLMWLTGQPDVAFGTAVSGRPTDVPGADSMVGLLINT 3298 Query 1318 LVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAW 1377 + +R + + + A L+ Q++ ++Q + + RA H L + + Sbjct 3299 VPVRATITPETTVASLMNQLQGAYTDTLDHQHLALNEI------HRATGHDQLFDTVFVY 3352 Query 1378 QDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQ 1437 ++ P+ L +Q + I T R + L+ + G E +G VEY T+VF+ Q Sbjct 3353 ENYPIDTAALLGVQE--LSITDFTNREYNHYPLSVQAVPGHE---LGLRVEYDTNVFDRQ 3407 Query 1438 AIDVLIERLRKVLVAV----------AAAPERTVSSIDALDGTERARLDEWGNRAVLTAP 1487 I L+ RL++VLVA+ A RT+ S D LD E +++ WGNRAVLT P Sbjct 3408 RIKRLVNRLQRVLVAIDRGYEGEVMTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDP 3467 Query 1488 APTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVAL 1547 PTPV+IP + A QV R P+A A+ GD S TYRELDEASNRLAH LA GA PG VA Sbjct 3468 GPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAF 3527 Query 1548 LFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHD 1607 L R A++++++VLKTGAAYLP+DPA+P R+ FM+ DA PVAA+TTA LRSRL +D Sbjct 3528 LIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYD 3587 Query 1608 LPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPAR 1666 L +ID+ D A+ P P +LAY+ YTSGTTG PK V +TH NVT+L ++L A Sbjct 3588 LAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHAD 3647 Query 1667 LSAA--QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL 1724 L + QVWSQ HS FD S WEIWGALL GGRLV+VPESV +SP+D H LL+ E VSVL Sbjct 3648 LPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVL 3707 Query 1725 TQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL 1784 QTP+A ML +GLES L+VAGEACP LVDRWAPGRVM+NAYGPTE TI AA+S PL Sbjct 3708 CQTPSAAGMLSPEGLESTTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPL 3767 Query 1785 RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVA 1844 G+G+ PIG PV GAALFVLD WLRP P GV GELY+AG GV GY R LTASRFVA Sbjct 3768 TAGTGVAPIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVA 3827 Query 1845 CPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQA 1904 CPFG +G RMYRTGDLV W +DGQLE+LGR D+QVKIRGYRIELGE+ ALA+L GV QA Sbjct 3828 CPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQA 3887 Query 1905 VVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNG 1964 VVIAREDRPGDKRLVGY T G DPA LR LA+ LP Y+VP AVVV+D +PLTVNG Sbjct 3888 VVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNG 3943 Query 1965 KLDHRALPAPEY-GDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAM 2023 KLD RALPAPEY N YRAP+ P E+ +A ++A+VLG+ERVGVDDSFF+LGGDS+ +M Sbjct 3944 KLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSM 4003 Query 2024 RVIA 2027 +V+A Sbjct 4004 QVVA 4007 Score = 725 bits (1872), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/1018 (46%), Positives = 602/1018 (60%), Gaps = 85/1018 (8%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV----------IE 1093 VY + + + L G LD + L AV V+ RH +L F G P Q++ +E Sbjct 1537 VYAVQLGITLSGSLDPQQLRDAVQAVIRRHPNLAARFVEQFGEPVQVLSVDPEIGWQFVE 1596 Query 1094 ARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAH 1153 D G D +R++R L + R L R AD+ H V H Sbjct 1597 FDSGDTGVD---------ERVERLCAAERSAVCKLGEQPVFRAALIRTADNLHRFVLTIH 1647 Query 1154 HIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIA 1213 HI DGWS+ L ++ AAY + P AP Y ++ W LG Sbjct 1648 HIVIDGWSLPVLLQEIFAAYFDQSL---PSAAP----YRNFVTW----LGA-----QDRD 1691 Query 1214 AQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSF 1273 A A W + L G PT P A RG + + + +AR + T Sbjct 1692 AAQAAWGSVLEG----FETPTLVAPPAQAGPRGVE-SFRLSEATTRTLGELARSQHTTVN 1746 Query 1274 MVVAAGLAVLLSKLSGSPDVAVGFPIAGR--SDPALDNLVGFFVNTLVLRVNLAGDPSFA 1331 V+ A A LL ++G DV G ++GR D++VG +NT+ +R + Sbjct 1747 TVLQAAWAQLLMWMTGQRDVVFGTAVSGRPVDLAGADSMVGLLINTVPVRATSGVATTVT 1806 Query 1332 ELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT-HHPLIQVMLAWQDNPV---GQLNL 1387 +LLGQ++ N V E + L LT H L + +++ P+ L++ Sbjct 1807 DLLGQLQRD-----HNDTVDHEHMA--LNEIHRLTGHDRLFDTLFVYENYPIDANALLSV 1859 Query 1388 GDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLR 1447 DL T +R + L+ + G E + VE+ T++F+A +I+ L++RLR Sbjct 1860 QDLAVTDF-----ASREYNHYPLSMVATPGHE---VVLRVEFDTEIFDAASIEALVDRLR 1911 Query 1448 KVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPE 1507 +VL A+A P R +S+ID LD E RLDEWGNRAVLT PAP SIP A V R+P+ Sbjct 1912 RVLDAMATDPGRRLSTIDLLDPQEHDRLDEWGNRAVLTRPAPALESIPASFAESVRRVPD 1971 Query 1508 AEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGA 1567 A A+ CGD S TYRELDEASNR+AH LAG GA PGE VA+L R AVV ++A+LKTGA Sbjct 1972 AVALSCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGA 2031 Query 1568 AYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPP 1626 AYLPIDPA+P R+ F+L DA PVAAV++A L +RL +P+I+V D A+ A T P Sbjct 2032 AYLPIDPAHPDARIEFVLKDAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLP 2091 Query 1627 MPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAW 1686 +PA ++AYI+YTSGTTG PKGV +THRNV +L +L A+L Q W+QCHS FD S W Sbjct 2092 VPAVDDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLELGQTWTQCHSLAFDYSVW 2151 Query 1687 EIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAV-------AMLPTQG- 1738 EIWG LL GGRL++VP++V SP D H +LVAE VS+L+QTP+A A+ P +G Sbjct 2152 EIWGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQTADALYPERGE 2211 Query 1739 -LESVALVVAGEACPAALVDRWA---PGR-VMLNAYGPTETTICAAI----SAPLRPGSG 1789 L+ +V GEA + W PG M+N YG TETT+ A+ A L + Sbjct 2212 QLKLQTVVFGGEALEPHRLSGWMHAHPGMPRMINMYGITETTVHASFREIGEADL--ANS 2269 Query 1790 MPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGG 1849 PIGVP+ + FVLD WLR VP GV GELY+AG G+ GY R+ LT++RFVACPFG Sbjct 2270 TSPIGVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGA 2329 Query 1850 SGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAR 1909 GARMYRTGDLV W ADGQL+++GR D+QVKIRGYRIELGEV AL L GV QA VIAR Sbjct 2330 PGARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIAR 2389 Query 1910 EDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHR 1969 EDRPGDKRLVGY T GAVDP RA LA+R+P Y+VPAA+VV+++LPLTVNGKL+ R Sbjct 2390 EDRPGDKRLVGYVT----GAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKLNTR 2445 Query 1970 ALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 ALPAPEY D + YRAPA VE+ + GI+A+VLG+ERVGVDDSFF+LGGDS+++M+V+A Sbjct 2446 ALPAPEYQDADQYRAPANAVEELLTGIYAQVLGVERVGVDDSFFDLGGDSISSMQVVA 2503 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/1037 (44%), Positives = 589/1037 (57%), Gaps = 82/1037 (7%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A+PLS Q +W + + + + ++ G +D L A+ + E R F Sbjct 7 ALPLSRGQLDIWLSHESGLAGAEWQLGLLGKIDGVVDHGLLQQAIRQALQEAEPARATFF 66 Query 1082 AVDGVPRQLVIEARRADLGC-DIVDATAWPADRLQRAIEEAARHSFDLATEIPL-----R 1135 DG Q ++ ++ D+ DA D +A E AA T +PL + Sbjct 67 EADGQVFQKPLDYSELEVPLYDVRDAD----DPEAKAREMAAEIQH---TPLPLTGRLVK 119 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYV--- 1192 LF+ D++ L + HHI+ DG +A ++ +S Y S G+ P+P Y Sbjct 120 FALFQTRDEQFYLFGLGHHISVDGLGMALVSRRISTIYTSLVTGK-----PVPEAYFGSL 174 Query 1193 -DYTLWQREILGDLDDSDSPIAAQLAYWENAL---AGMPERLRLPTARPYPPVADQRGAS 1248 D + D D LAYW L G+ + L PT P+ A AS Sbjct 175 RDLVECEMSYESSADYQDD-----LAYWSENLPPDTGLDQGLA-PT--PHGKNAYTPSAS 226 Query 1249 LVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPD-VAVGFPIAGRSDPAL 1307 + +D PA V + ++ +++ + V A A+L S + D VA+ FP++ R P Sbjct 227 VPMD-PAIVGR-IKELSKTLRIRRYSVTTAACALLAQSWSSTGDQVALDFPVSRRVSPES 284 Query 1308 DNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTH 1367 L L ++ + E V R ++Q P V RL AL Sbjct 285 KTLPAMLAGVAPLVLDAPPQLTVGEFCKHVDIRIRELLQHQRFP----VHRLGDGGALR- 339 Query 1368 HPLIQVMLAWQDNPVGQLNLGDLQATP-MPIDTRTARMDLVFSLAERFSEGSE--PAG-- 1422 G QA+ + ++ +R+ L F+ AE + + P G Sbjct 340 --------------------GPRQASNRLAVNFIPSRLTLDFAGAEATASYTNHGPMGHF 379 Query 1423 ----IGGAVEYRTDV------FEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTER 1472 IG E F + L ERL ++ A+AA P ++++ L +E Sbjct 380 GLFFIGAGEELFLSTAGAGQPFANFEVPELAERLGAIVAAMAADPAMPLAAVRLLAESES 439 Query 1473 ARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAH 1532 RL GN + L+ AP VSIP+ AA+VA P+A A+ ++TYRELDEA+NR AH Sbjct 440 DRLATIGNHSALSESAPDAVSIPERFAARVAEAPDAAALTFEGRTLTYRELDEAANRFAH 499 Query 1533 RLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVA 1592 L G GPG VAL+ R +V+A++ K GAAY+P+DPA P RV F+L DA PVA Sbjct 500 ALLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVPVDPAVPAARVRFILDDASPVA 559 Query 1593 AVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGI 1651 VTTA LRSR GHDL +ID+ D A+A+ P T P ++AY++YTSGTTG PKGV + Sbjct 560 VVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGVAV 619 Query 1652 THRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPND 1711 TH+N+T L A L RL VW CHS FDAS WEI ALL GGRLV+VPE+VA SP D Sbjct 620 THKNLTHLIAVLEERLPKPGVWPLCHSLAFDASVWEISNALLRGGRLVVVPEAVAGSPED 679 Query 1712 FHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGP 1771 FH LLVAE V+ LTQTP+AVAML GLES+ L V GEACP ALVDRWA R M+NAYGP Sbjct 680 FHDLLVAEQVTFLTQTPSAVAMLSPDGLESMTLAVVGEACPPALVDRWATNRTMINAYGP 739 Query 1772 TETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGY 1831 TETTIC S+PL PGS + PIG + ALFVLD WLRPVP GVAGELY+AG GV GY Sbjct 740 TETTICVTSSSPLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGY 799 Query 1832 WRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEV 1891 R+GLTASRFV CPFG GARMYRTGDLV W DGQLE+LGR D+QVKIRGYRIELGEV Sbjct 800 IGRSGLTASRFVPCPFGEPGARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEV 859 Query 1892 ATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAA 1951 +ALA L GV A I REDRPGD+RLVGY T G DP +RA+LA RLP Y+VP A Sbjct 860 QSALAALDGVESAAAIMREDRPGDRRLVGYIT----GTADPVDIRAELADRLPPYMVPTA 915 Query 1952 VVVIDALPLTVNGKLDHRALPAPEYGDT-NGYRAPAGPVEKTVAGIFARVLGLERVGVDD 2010 +VV+ ALPLT + KLD RALPAPEY + YRAP+ PVE+ +A I+A+VLG+ER+GVDD Sbjct 916 IVVLPALPLTSSNKLDTRALPAPEYANAEKNYRAPSNPVEEVLADIYAQVLGVERIGVDD 975 Query 2011 SFFELGGDSLAAMRVIA 2027 SFF+LGGDS+ +M+V+A Sbjct 976 SFFDLGGDSILSMQVVA 992 Score = 105 bits (262), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 178/660 (27%), Positives = 281/660 (43%), Gaps = 85/660 (12%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AYI+ TSGTTG PK V ++H ++A D + G T QC L D SV EI+G Sbjct 2099 AYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLELG--QTWTQCHSLAFDYSVWEIWGP 2156 Query 635 AACGARL--VRSAAMKT-GDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRS 690 G RL V A +++ DL A+ LVA + +++ P+A + L AD + + Sbjct 2157 LLNGGRLLMVPDAVVRSPEDLHAM---LVAEQVSMLSQTPSAFYALQTADALYPERGEQL 2213 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGI-SLLSSYGPTEATVVATFLPIVCDQTTMDGA 749 +L+ +V GGEA+ + W+ A G+ +++ YG TE TV A+F I + + + Sbjct 2214 KLQTVVFGGEALEPHRLSGWMH--AHPGMPRMINMYGITETTVHASFREI--GEADLANS 2269 Query 750 LLRLGRPILPNTVFLAFG-----EVVIVGDLVADGYLGIDGDGFGTVTAADGSRRR---- 800 +G P+ + F+ G V +VG+L Y+ +G G ++ +D + R Sbjct 2270 TSPIGVPLEHLSFFVLDGWLRQVPVGVVGEL----YVAGEGLACGYISRSDLTSTRFVAC 2325 Query 801 --------AFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVA 852 + TGD V A+G + GR D VKI G R+++ EV + V A Sbjct 2326 PFGAPGARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAA 2385 Query 853 VELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNG 908 V G V + + + AA A RI +V +V + ++P NG Sbjct 2386 VIAREDRPGDKRLVGYVTGAVDPVKARAALAERIPAYMVPAA-----IVVMESLPLTVNG 2440 Query 909 KIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLI 967 K+++ LP P++ A A L+ I+++ LG +G D S G S+ + Sbjct 2441 KLNTRALPA-PEYQDADQYRAPANAVEELLTGIYAQVLGVERVGVDDSFFDLGGDSISSM 2499 Query 968 RILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTG--EDRFRPLVAAQRPAAIPL 1025 +++ R G D+ T + LA D +G + P+VA P+ Sbjct 2500 QVVARARA-AGLVCRPRDIFVEQTVSRLAQVVTLADGESGVADTGVGPVVAT------PI 2552 Query 1026 SFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRT-VFPAVD 1084 R L+ LD P +N V L++ + + A + V+ H LR V A + Sbjct 2553 ---MRWLYSLDG---PIDEFNQTVVLQVPAEVTEADVIAVLQAVLDHHAMLRLRVADAEN 2606 Query 1085 G---VPRQLVIEARRADLGCDIVDATAWPADRLQ--RAIEEAARHSFDLATEIPLRTWLF 1139 G VP ++A D C + + T AD L RA A S A +P Sbjct 2607 GDLTVPEPGSVDA--CDCLCTVGELT---ADTLAAVRAQLNPATGSMLTAAWVP------ 2655 Query 1140 RIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQR 1199 + L + HH+A D S L DL+ A+A +G+ LP + W R Sbjct 2656 ----ETRQLALMIHHLAVDAVSWRILLEDLNIAWAQHRSGQP---VVLPTPGTSFGRWSR 2708 Score = 100 bits (250), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 224/903 (25%), Positives = 344/903 (39%), Gaps = 124/903 (13%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L+ RG PG + TD+++ ++ AG Y D A + R I + D Sbjct 501 LLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVPVDPAVP-AARVRFILD--DASP 557 Query 535 VTVVDVAATQLAVVGHD-ELRKVVDERVTQVTHDALLATK---TAYIMPTSGTTGQPKLV 590 V VV A + GHD + + D + + A+ + AY++ TSGTTG PK V Sbjct 558 VAVVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGV 617 Query 591 RISHGSL----AVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAA 646 ++H +L AV + + + W C L D SV EI G RLV Sbjct 618 AVTHKNLTHLIAVLEERLPKPGVWPL------CHSLAFDASVWEISNALLRGGRLVVVPE 671 Query 647 MKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSA 706 G D LVA + T + + +L DG ++++ + + GEA + Sbjct 672 AVAGSPEDFHDLLVAEQVTFLTQTPSAVAMLSPDG--LESM------TLAVVGEACPPAL 723 Query 707 VDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFLAF 766 VD+W + +++++YGPTE T+ T G+++ LP T Sbjct 724 VDRW-----ATNRTMINAYGPTETTICVT-----SSSPLEPGSVVVPIGSALPRTALFVL 773 Query 767 ------------GEVVIVGDLVADGYLGIDGDG--------FGTVTAADGSRRRAFATGD 806 GE+ + GD V GY+G G FG A R + TGD Sbjct 774 DPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFGEPGA------RMYRTGD 827 Query 807 RVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----V 862 V +G + GR D VKI G R+++ EV +A V A + G V Sbjct 828 LVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAAIMREDRPGDRRLV 887 Query 863 WFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWS 922 + + + A A R+ +V +V +P +P + K+D+ LP P+++ Sbjct 888 GYITGTADPVDIRAELADRLPPYMVPTA-----IVVLPALPLTSSNKLDTRALPA-PEYA 941 Query 923 AAGLNT-AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWR 980 A N A + L+ I+++ LG IG D S G S+ ++++ R G + Sbjct 942 NAEKNYRAPSNPVEEVLADIYAQVLGVERIGVDDSFFDLGGDSILSMQVVARARA-AGIQ 1000 Query 981 LSLLDLIGADTAANLADYAPTP------DAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWF 1034 D+ T A LA A D TG P++ R A + L Sbjct 1001 CRPRDVFVEQTVARLASVATVATEIGVVDDGTGSAAPTPIIHWLREAGGATDEFNQTL-- 1058 Query 1035 LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEA 1094 +Q P V V L+ LD RH +LR DG LV +A Sbjct 1059 --VVQAPTGVTEPDVVAVLQALLD-------------RHATLRLRVQDSDGEWSLLVPDA 1103 Query 1095 RRADL-GCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAH 1153 D C V D L + AAR + A + R LV + H Sbjct 1104 ATVDARDCLSV------VDTLSDDVVLAARAKLNPAAGAMVSALWVRQTSQ---LVLIIH 1154 Query 1154 HIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIA 1213 H+A DG S L DL+ A+A +G+ LP + W + + ++ + Sbjct 1155 HLAVDGVSWRILLEDLNIAWAQHHSGQQ---VQLPAGGTSFLRWSKRLADHAHTAE--VT 1209 Query 1214 AQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNA--T 1271 AQ W LA + LP +P G P + +Q + + +A Sbjct 1210 AQADAWREILA---KPAALPAVQPDTDTHASAGRFSATLDPETTRQLLGEVPAAFHAGVQ 1266 Query 1272 SFMVVAAGLA-VLLSKLSGSPDVAVGFPIAGR-----SDPALDNLVGFFVNTLVLRVNLA 1325 ++VA GLA SG+P + V GR SD L VG+F + + +A Sbjct 1267 DILLVAFGLAWAEFLNRSGTP-ITVDVEGHGRHEELASDIDLSRTVGWFTTKYPVALTVA 1325 Query 1326 GDP 1328 P Sbjct 1326 DVP 1328 Score = 94.7 bits (234), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 199/805 (25%), Positives = 308/805 (39%), Gaps = 148/805 (18%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY+ TSGTTG PK V ++H ++ A+ G Q L D+SV EI+G Sbjct 3615 AYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGA 3674 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 G RLV S DL L+ + + + + P+A +L +G Sbjct 3675 LLHGGRLVVVPESVGSSPDDLHNLL--ITEKVSVLCQTPSAA-GMLSPEG--------LE 3723 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALL 751 +++ GEA VD+W + G ++++YGPTEAT+ A + + T + Sbjct 3724 STTLIVAGEACPTELVDRW-----APGRVMINAYGPTEATIYAA----MSEPLTAGTGVA 3774 Query 752 RLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLG---IDGDGFGTVTAADGS 797 +G P+ +F+ GE+ + G VA GY+G + F + + Sbjct 3775 PIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE-T 3833 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 R + TGD V ++G + GR D VKI G R+++ E+ +A+ V V Sbjct 3834 GERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIARE 3893 Query 858 GSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD 913 G V + + + A A + +V VV + IP NGK+D Sbjct 3894 DRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTA-----VVVLDTIPLTVNGKLDRR 3948 Query 914 NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPE 972 LP SAA A + L+ ++++ LG +G D S G S+ ++++ Sbjct 3949 ALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR 4008 Query 973 TRRYLGWRLSLLDLIGADTA------------ANLADYAPTP-------------DAPTG 1007 R G + D+ T +++ D P D PTG Sbjct 4009 ARA-AGIQCRPRDIFVEQTVAGVARVAVAAGESHVVDEGVGPVVATPIMRWLREVDGPTG 4067 Query 1008 EDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLR---GYLDTEALGA 1064 + F V Q PA + L L L R A LRLR DT+ Sbjct 4068 Q--FNQTVITQAPAGVTEDDVVVILQAL--LDRHA-------TLRLRVEDTQEDTDEWSL 4116 Query 1065 AV--ADVVGRHESLRTVFPAVDGVPRQLVIEAR-RADLGCDIVDATAWPADRLQRAIEEA 1121 V A VG E LRT VD + +++EAR R D + + W + Q Sbjct 4117 LVPEAGAVGARECLRT----VDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ------ 4166 Query 1122 ARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRA 1181 LV + HH+A DG S L DL+ A+A C G++ Sbjct 4167 --------------------------LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS 4200 Query 1182 PDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPP- 1240 + LP + W +L + +D+ LA A+ +P+ LP +P Sbjct 4201 IE---LPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQ--ALPPVQPDTDT 4252 Query 1241 --VADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFP 1298 A Q ASL V+ + +V R ++VA GLA ++ D +G Sbjct 4253 YVTAGQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLA--WTEFLNRSDTPIGVD 4309 Query 1299 IAGR-------SDPALDNLVGFFVN 1316 + G SD L VG+F Sbjct 4310 VEGHGRYDELASDVDLSRTVGWFTT 4334 Score = 82.0 bits (201), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 121/453 (27%), Positives = 185/453 (41%), Gaps = 67/453 (14%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AY++ TSGTTG PK V I+HG++ D + G Q L D+SV EI+G Sbjct 5109 AYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGA 5168 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETTIV-DLPTAVWQLLCADGDAIDAIGRS 690 G RLV S A DL AL LV+ ++ P+AV +++ +G A Sbjct 5169 LLHGGRLVIVPESIAGSPDDLHAL---LVSEGVNVLYQTPSAV-RMMSPEGLEGTA---- 5220 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGAL 750 +V+ GEA VD+W ++++YGPTE+T+ A Sbjct 5221 ----LVVAGEACPTEVVDRWAVDRV-----MINAYGPTESTIYAA--------------- 5256 Query 751 LRLGRPILPNTVFLAFGEVVIVG-DLVADGYL-----GIDGDGF----------GTVTAA 794 + P+ P + + G V G V D +L G+ G+ + + Sbjct 5257 --ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGL 5314 Query 795 DGSR----------RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAE 844 G+R R + TGD V +G + GR D VKI G R+++ E+ +++ Sbjct 5315 TGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSD 5374 Query 845 DPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPR 904 V V G AAA + + L + V + VV + +P Sbjct 5375 VDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPA-AVVTLETLPL 5433 Query 905 KPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGS 963 NGK+D LP P++ +A A + L+ I++ LG IG D S G S Sbjct 5434 TVNGKLDRRALPA-PEYQSAQRYRAPETETEKTLAGIFAHVLGVERIGLDDSFFDLGGDS 5492 Query 964 LDLIRILPETRRYLGWRLSLLDLIGADTAANLA 996 + +R+ L LS+ L A T A L+ Sbjct 5493 ISAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 5525 >gi|254822516|ref|ZP_05227517.1| linear gramicidin synthetase subunit D [Mycobacterium intracellulare ATCC 13950] Length=4710 Score = 1384 bits (3583), Expect = 0.0, Method: Compositional matrix adjust. Identities = 792/1477 (54%), Positives = 984/1477 (67%), Gaps = 51/1477 (3%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A A+++ TSGTTG+PK V ++H ++ A+ G QC L D SV E Sbjct 1969 ADDVAHVIYTSGTTGRPKGVAVTHANVTQLFGALDAGVELGPDQVWSQCHSLAFDFSVWE 2028 Query 631 IFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRS 690 I+G G RLV + L L+ T++ + +L G ++ + Sbjct 2029 IWGALLHGGRLVVVPDTEARSPEELRAKLIGERVTVLTQTPSALGMLSPRG--LETV--- 2083 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGAL 750 +V+G E VD+W + G +++ YGPTE T+ + P + G Sbjct 2084 ---TVVVGAEPCPGELVDRW-----APGRVMVNVYGPTETTMWVSHSPPLTAGRARSGPP 2135 Query 751 LRLGRPILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGS 797 +G P+ +F+ GE+ + G V GYLG G A G+ Sbjct 2136 A-IGSPVAGAALFVLDGCLRPVPAGVVGELYVAGAGVGVGYLGRAGLTASRFVACPFGGA 2194 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 R + TGD D +G + GR D VKI G R+++ E+ +AE + AV Sbjct 2195 GARMYRTGDLARWDRDGQLHYVGRADEQVKIRGYRIELGEIRSALAELEGIEQAAVLARE 2254 Query 858 GSLGVWFKSQRTREGEQDAAAAT-----RIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDS 912 +R G AA + R+ L + V + VV + +P NGK+D+ Sbjct 2255 DR-----ADERRLVGYVTGAADSADIRARLGQRLPTYMVPAAVVV-LDAMPLTVNGKLDT 2308 Query 913 DNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILP 971 LP P + AG A L +++R LG +G D S G SL +R++ Sbjct 2309 AALP-APDYRDAGRYRAPDNAVEETLVGVYARVLGVERVGVDDSFFDLGGDSLSAMRLIT 2367 Query 972 ETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRR 1031 L L++ + A T A LA G R LVA +RPA +PLSFAQ R Sbjct 2368 AINADLDAGLTVRSVFEAPTVAQLALRVEA-----GAGRAGRLVAGERPALLPLSFAQTR 2422 Query 1032 LWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLV 1091 LWF+DQLQ P+P+YNMAVALRL G LD +A+GAA+ DVV RHESLRT+F A +G P+Q+V Sbjct 2423 LWFIDQLQGPSPMYNMAVALRLSGRLDADAMGAALDDVVARHESLRTIFLAPEGAPQQVV 2482 Query 1092 IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAV 1151 + A+RAD+ +VDAT WP+ L A ++AAR++FDLATEIPLR WLF +DEHVLVAV Sbjct 2483 LPAKRADVHWQVVDATRWPSSWLAEATQDAARYTFDLATEIPLRAWLFHTGEDEHVLVAV 2542 Query 1152 AHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSP 1211 HHIAADGWSV PL DL AYA+R GRAPDWAPLPVQYVDYTLWQR GDLDD DSP Sbjct 2543 VHHIAADGWSVTPLVRDLGEAYAARRGGRAPDWAPLPVQYVDYTLWQRGRFGDLDDPDSP 2602 Query 1212 IAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNAT 1271 IAAQL YWE ALAG+PE + LPT RPYP VAD RG+S+ V WPA++Q QV +AR HNAT Sbjct 2603 IAAQLDYWERALAGLPEHVELPTDRPYPLVADHRGSSVDVHWPAALQHQVAELARAHNAT 2662 Query 1272 SFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFA 1331 SFMVV A LAVLLS LS SPDVAVGFPIAGRSDPALD +VGFFVNTLVLRV+L+GDP+ A Sbjct 2663 SFMVVQAALAVLLSALSASPDVAVGFPIAGRSDPALDEVVGFFVNTLVLRVDLSGDPTVA 2722 Query 1332 ELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQ 1391 ELLG+VR RSLAAYE+QDVPFEVLV+RL P R + HHPL+QVMLAWQ+N ++LGD++ Sbjct 2723 ELLGRVRRRSLAAYEHQDVPFEVLVERLNPARDMAHHPLVQVMLAWQNNDPVDMSLGDVR 2782 Query 1392 ATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLV 1451 ATP+P++T+ ARMDLV+SLAER+ E +P GI GAVE+RTDVF+A +I+ L+ RL+ VL Sbjct 2783 ATPLPLETQVARMDLVWSLAERWDEDGQPVGIAGAVEFRTDVFDAASIESLVTRLQHVLA 2842 Query 1452 AVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAV 1511 A+ A P R +S+ID LD +ERA LD GNRAVLT PA SIP + AAQVAR PEA A+ Sbjct 2843 AMTADPTRPLSAIDVLDESERAHLDAIGNRAVLTRPATARASIPALFAAQVARDPEAVAI 2902 Query 1512 CCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLP 1571 CG+ + TYRE+ E +NRLAHRL GCGA PG+ VA+ R A A+VA++AVLKTGAAY+P Sbjct 2903 TCGERAWTYREVYEITNRLAHRLIGCGAAPGQRVAVAMPRSAEAIVAILAVLKTGAAYVP 2962 Query 1572 IDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAA 1630 IDPA P R+ FML DA P+AAVTTA +R RL IIDV D ALA P T P P+ Sbjct 2963 IDPALPTARIEFMLTDAEPIAAVTTAEVRPRLGAFAGHIIDVDDPALATQPATGLPDPSP 3022 Query 1631 VNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWG 1690 ++AY++YTSGTTG PKGV +TH NVT+L S+ A+L +VW CHS FD S WEI+G Sbjct 3023 DDIAYVIYTSGTTGVPKGVAVTHHNVTQLLRSVDAQLDLGRVWGHCHSPAFDFSVWEIFG 3082 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 ALL GGRLV+VP+ + SP D H LL+AE V+VL+QTP+AVA L GL+SVALVV GE Sbjct 3083 ALLRGGRLVVVPDDIVGSPEDLHALLIAERVTVLSQTPSAVAALSPHGLDSVALVVGGEP 3142 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 CP ++DRWAPGRVM+N YGPTETT+ AA++APL GS PIG PV GAALFVLD WLR Sbjct 3143 CPVEVMDRWAPGRVMVNQYGPTETTMYAAMTAPLTAGSAPVPIGSPVPGAALFVLDRWLR 3202 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 VP GV GELYIAG GV GY RA LTASRFVACPFGG+G RMYRTGD+V W DGQLE Sbjct 3203 AVPPGVVGELYIAGRGVAAGYLGRAALTASRFVACPFGGNGTRMYRTGDVVRWGRDGQLE 3262 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 +LGR D+QVKIRG+RIELGE+ +ALAEL GV QA VIAR D P RLVGY T G Sbjct 3263 YLGRADEQVKIRGHRIELGEIRSALAELDGVEQAAVIARND-PAAARLVGYVT----GTA 3317 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DP+ RA+LA+RLP Y+VP+AVVV+DALPLT NGKLD RALPAP+Y NGYRAP +E Sbjct 3318 DPSETRARLAERLPSYMVPSAVVVLDALPLTANGKLDTRALPAPDYQGGNGYRAPENAIE 3377 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 + +AGI+A+VLG++RVGVDDSFF+LGGDS+ +M+V+A Sbjct 3378 QILAGIYAQVLGVQRVGVDDSFFDLGGDSILSMQVVA 3414 Score = 1383 bits (3580), Expect = 0.0, Method: Compositional matrix adjust. Identities = 850/1748 (49%), Positives = 1081/1748 (62%), Gaps = 102/1748 (5%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 LV+RGA PG + + + I ++A G Y D + + R + GD Sbjct 809 LVERGAGPGQRVAVAVPRSAEAIVAILAVLKTGAAYVPIDPSVP-AARVQFVL--GDAAP 865 Query 535 VTVVDVAATQLAVVGH-DELRKVVDERVTQVTHDAL---LATKTAYIMPTSGTTGQPKLV 590 + V A + + G ++ + D V L A AY++ TSG+TG PK V Sbjct 866 IAAVTTAEVRPQLGGFAGQIIDIDDPAVAGQPATGLPVPSADSIAYLIYTSGSTGVPKGV 925 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTG 650 ++H ++ ++I G T QC L D SV E+FG G RLV + Sbjct 926 AVTHSNVTQLLESIDAQLDVGQVWT--QCHSLAFDFSVWEVFGALLHGGRLV----VVPD 979 Query 651 DLAALVDDLVA---RE--TTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCS 705 D+ DDL A RE + + P+A + L AD A + + +L+ +V GGEA+ Sbjct 980 DVVRSPDDLRALLVREQVSVLSQTPSAFYALQSADALAPELGEQLKLQTVVFGGEALEPR 1039 Query 706 AVDKWLESAASQGI-SLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL 764 + WL G+ +++ YG TE TV A+F I+ + +D + +G P L N F Sbjct 1040 RLSTWLHH--HPGLPRMINMYGITETTVHASFREIL--RGDVDNNVSPIGVP-LGNLAFF 1094 Query 765 AF------------GEVVIVGDLVADGYLGIDGDGFGTVTA----ADGSRRRAFATGDRV 808 F GE+ + G +A GY+G G A A G+R + TGD V Sbjct 1095 VFDGWLRPVPVGVVGELYVAGGGLATGYVGRPGLSASRFVACPFGAPGAR--MYRTGDLV 1152 Query 809 TVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWF 864 A+G + GR D VKI G R+++ E+ +A+ V AV + G V + Sbjct 1153 RWSADGQLQYIGRADEQVKIRGYRIELGEIRAALADVEGVEQAAVLVREDRAGDKRLVGY 1212 Query 865 KSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAA 924 + E A R+ +V V V +P NGK+D+ LP P++S Sbjct 1213 VTGAADPSEIRARLGRRLPTYMVPAAVVVLDV-----LPLTVNGKLDTRALP-APEYSDV 1266 Query 925 GLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSL 983 A L+ I+++ LG +G D S G SL +R++ L +S+ Sbjct 1267 DRYRAPASAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSLSAMRLIAAVNAALDAGVSV 1326 Query 984 LDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAP 1043 L T A LA P G +R + AA RPA +PLSFAQ RLWF+DQLQ P+P Sbjct 1327 RALFEVPTVAQLA-----PRLDEGAERLSRVAAADRPAVVPLSFAQSRLWFIDQLQGPSP 1381 Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDI 1103 +YNMA ALRLRG L EAL AA+ DVVGRHESLRTVF DG P+Q+V+ A D+G ++ Sbjct 1382 MYNMAAALRLRGPLQVEALRAALVDVVGRHESLRTVFAVSDGTPQQVVLPAEGVDIGWEV 1441 Query 1104 VDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVA 1163 +DA W R++ ++ AA ++FDL+ EIPL+ LFR +DDEHVLVAV HHIAADGWS+ Sbjct 1442 IDAAGWSPARIKEGVDAAADYAFDLSAEIPLQAKLFRASDDEHVLVAVVHHIAADGWSLN 1501 Query 1164 PLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENAL 1223 PL DL AYA RCAGRAP W+PL VQYVDYTLWQR GDLDD +SPI QLAYWE L Sbjct 1502 PLVHDLGVAYAGRCAGRAPQWSPLAVQYVDYTLWQRAQFGDLDDPESPIVEQLAYWERTL 1561 Query 1224 AGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVL 1283 AG+PER+ LPT RPYP VAD RGA++ +DWPA +QQ +R +AR HNATSFMVV A LAVL Sbjct 1562 AGLPERVELPTDRPYPAVADYRGANVDIDWPAELQQHIRAVARAHNATSFMVVQAALAVL 1621 Query 1284 LSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLA 1343 L K++ + DVAVGFPIAGR DPALD LVGFFVNTLVLRV+LAGDPS A++L +VR SLA Sbjct 1622 LGKIAATSDVAVGFPIAGRRDPALDELVGFFVNTLVLRVDLAGDPSVADVLARVRRSSLA 1681 Query 1344 AYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTAR 1403 AYENQDVPFE LV+RL PTR+L HHPL QVMLAWQ N +L+LG+L+ T +P+ TRTAR Sbjct 1682 AYENQDVPFEFLVERLNPTRSLAHHPLTQVMLAWQGNDPAELSLGELRITAVPVQTRTAR 1741 Query 1404 MDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSS 1463 DL FSL ER S PAGIGG VE+RTD+F+A I VL ERLR+VLVA+AA P R +SS Sbjct 1742 TDLTFSLFERRSGDGRPAGIGGTVEFRTDLFDADTIRVLTERLRRVLVAMAADPGRRLSS 1801 Query 1464 IDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYREL 1523 ID LD E ARLD+ NR+ L P+ S+P + A V R P A A+ C S TY ++ Sbjct 1802 IDVLDDDEHARLDQCANRSALRRPS-AGASVPALFGAWVQRAPHAVAIRCAGRSWTYEQV 1860 Query 1524 DEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAF 1583 + +NRLAH L G G G G+ V LL ER A AV+A++ VLKTGAAY+P+DPA P R+ F Sbjct 1861 ESDANRLAHLLVGRGVGRGQRVGLLLERSAEAVIAILGVLKTGAAYVPMDPAVPAARIGF 1920 Query 1584 MLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPM-PAAVNLAYILYTSG 1641 M+ DA A VT+A LRSRL PI++V D ALA +P TP PAA ++A+++YTSG Sbjct 1921 MVADAGMRAVVTSAELRSRLGEFGGPIVEVDDPALAPHPATPVAAGPAADDVAHVIYTSG 1980 Query 1642 TTGEPKGVGITHRNVTRLFASLPA--RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLV 1699 TTG PKGV +TH NVT+LF +L A L QVWSQCHS FD S WEIWGALL GGRLV Sbjct 1981 TTGRPKGVAVTHANVTQLFGALDAGVELGPDQVWSQCHSLAFDFSVWEIWGALLHGGRLV 2040 Query 1700 IVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRW 1759 +VP++ A SP + L+ E V+VLTQTP+A+ ML +GLE+V +VV E CP LVDRW Sbjct 2041 VVPDTEARSPEELRAKLIGERVTVLTQTPSALGMLSPRGLETVTVVVGAEPCPGELVDRW 2100 Query 1760 APGRVMLNAYGPTETTICAAISAPLRPG---SGMPPIGVPVSGAALFVLDSWLRPVPAGV 1816 APGRVM+N YGPTETT+ + S PL G SG P IG PV+GAALFVLD LRPVPAGV Sbjct 2101 APGRVMVNVYGPTETTMWVSHSPPLTAGRARSGPPAIGSPVAGAALFVLDGCLRPVPAGV 2160 Query 1817 AGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTD 1876 GELY+AGAGVGVGY RAGLTASRFVACPFGG+GARMYRTGDL W DGQL ++GR D Sbjct 2161 VGELYVAGAGVGVGYLGRAGLTASRFVACPFGGAGARMYRTGDLARWDRDGQLHYVGRAD 2220 Query 1877 DQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLR 1936 +QVKIRGYRIELGE+ +ALAEL G+ QA V+AREDR ++RLVGY T GA D A +R Sbjct 2221 EQVKIRGYRIELGEIRSALAELEGIEQAAVLAREDRADERRLVGYVT----GAADSADIR 2276 Query 1937 AQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGI 1996 A+L QRLP Y+VPAAVVV+DA+PLTVNGKLD ALPAP+Y D YRAP VE+T+ G+ Sbjct 2277 ARLGQRLPTYMVPAAVVVLDAMPLTVNGKLDTAALPAPDYRDAGRYRAPDNAVEETLVGV 2336 Query 1997 FARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLL- 2055 +ARVLG+ERVGVDDSFF+LGGDSL+AMR+I AIN L+A L VR++ A + L+ + Sbjct 2337 YARVLGVERVGVDDSFFDLGGDSLSAMRLITAINADLDAGLTVRSVFEAPTVAQLALRVE 2396 Query 2056 ---GRDARPTSDPR---------------LVSVHGDNPTEVHASDLTLDRFIDADTLATA 2097 GR R + R + + G +P A L L +DAD + A Sbjct 2397 AGAGRAGRLVAGERPALLPLSFAQTRLWFIDQLQGPSPMYNMAVALRLSGRLDADAMGAA 2456 Query 2098 V-NLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDGRLICLVR------AESDEDAR 2150 + ++ LRT+ L A + +VL +R DV +++ R AE+ +DA Sbjct 2457 LDDVVARHESLRTIFL--APEGAPQQVVLP-AKRADVHWQVVDATRWPSSWLAEATQDAA 2513 Query 2151 RRLEKTFD 2158 R TFD Sbjct 2514 R---YTFD 2518 Score = 1308 bits (3385), Expect = 0.0, Method: Compositional matrix adjust. Identities = 736/1327 (56%), Positives = 904/1327 (69%), Gaps = 49/1327 (3%) Query 767 GEVVIVGDLVADGYL---GIDGDGFGTVTAADGSRRRAFATGDRV----TVDAEGFPVFS 819 GE+ + G+ V GY G+ F + R + TGD V + EG + Sbjct 35 GELYLAGEGVGVGYWRRPGLTASRFMACPFGEPGTR-MYRTGDLVCWGRSGSGEGQLQYL 93 Query 820 GRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAAAA 879 GR D VK+ G R+++ E+ + E V AV + G +R AA Sbjct 94 GRADEQVKVRGYRIELGEIRAALLEVEGVEHAAVLVREDRAG----EKRLVGYVTGAADP 149 Query 880 TRIRLVL---VSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAA 936 T IR L + + VV + +P NGK+D+ LP G E+ Sbjct 150 TDIRARLGRRLPTYMVPSAVVALDALPMTVNGKLDTRALPAPDYQGGNGYRAPESAIEEI 209 Query 937 GLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLIGADTAANL 995 L+ I++R LG +G D S G SL +R++ L L + L + T A L Sbjct 210 -LAGIFARVLGVERVGIDDSFFHLGGDSLSAMRLVSAVNTGLDAHLGVRTLFESPTVAEL 268 Query 996 ADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRG 1055 A P G +VAA+RPA +PLSFAQ RLWFLDQL P+PV+NM+VALRLRG Sbjct 269 A-----PRVCGGGSTLARVVAAERPAVVPLSFAQSRLWFLDQLHGPSPVHNMSVALRLRG 323 Query 1056 YLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQ 1115 LD +A+G A+ DVV RHESLRTVF A +G PRQ+V+ RA +G ++DA WP RL Sbjct 324 PLDPDAMGTALGDVVARHESLRTVFVASEGTPRQVVVPVERARVGWQVIDAGGWPVGRLS 383 Query 1116 RAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYAS 1175 +AIE A H FDL+ EIPLR LFR+A+D+HVLVAVAHHIAADGWS+ PL DL AAY Sbjct 384 QAIETEACHRFDLSNEIPLRAKLFRLAEDDHVLVAVAHHIAADGWSLTPLVRDLGAAYVR 443 Query 1176 RCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTA 1235 R G+APDWAPLPVQYVDYTLWQR GDLDD SPIAAQL YW++ALAGMPERL LPT Sbjct 444 RSRGQAPDWAPLPVQYVDYTLWQRAQFGDLDDPGSPIAAQLRYWQDALAGMPERLELPTD 503 Query 1236 RPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAV 1295 RPYPPVAD RGA + V+WPA +QQ+V ++AR HNAT+FMVV A LAVLLSK+S S DVAV Sbjct 504 RPYPPVADHRGARIDVEWPAELQQRVAQVARAHNATTFMVVQAALAVLLSKVSASSDVAV 563 Query 1296 GFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVL 1355 GFPIAGR DPALD++VGFFVNTLVLRV+L+GDPS AEL+ +VR RSLAAYE+QDVPFEVL Sbjct 564 GFPIAGRGDPALDDVVGFFVNTLVLRVDLSGDPSVAELVARVRQRSLAAYEHQDVPFEVL 623 Query 1356 VDRLKPTRALTHHPLIQVMLAWQ------DNPVGQLNLGDLQATPMPIDTRTARMDLVFS 1409 VDRL PTR L HHPL+QV+LAWQ D P L LGD++ TP+P+DT+ ARMDLVFS Sbjct 624 VDRLHPTRDLAHHPLVQVVLAWQNLPWQHDGPAAGLELGDVRVTPLPVDTQVARMDLVFS 683 Query 1410 LAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDG 1469 LAER+ E PAGIGG VE+RTDVF+A +I+ LIERLR++L A+ A P+R +S+ID LD Sbjct 684 LAERWDEEGAPAGIGGMVEFRTDVFDADSIETLIERLRRMLAAMTADPDRPLSAIDLLDA 743 Query 1470 TERARLDEWGNRAVLTAPAPTP-VSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASN 1528 ER RLD+ GNRAVLT P+ VSIP + AAQVAR P A A+ CG S TYR L EA+N Sbjct 744 AERERLDDIGNRAVLTMPSMAALVSIPALFAAQVARGPGAVAITCGGRSFTYRHLYEATN 803 Query 1529 RLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDA 1588 RLAH L GAGPG+ VA+ R A A+VA++AVLKTGAAY+PIDP+ P RV F+LGDA Sbjct 804 RLAHLLVERGAGPGQRVAVAVPRSAEAIVAILAVLKTGAAYVPIDPSVPAARVQFVLGDA 863 Query 1589 VPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPK 1647 P+AAVTTA +R +L G IID+ D A+A P T P+P+A ++AY++YTSG+TG PK Sbjct 864 APIAAVTTAEVRPQLGGFAGQIIDIDDPAVAGQPATGLPVPSADSIAYLIYTSGSTGVPK 923 Query 1648 GVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAA 1707 GV +TH NVT+L S+ A+L QVW+QCHS FD S WE++GALL GGRLV+VP+ V Sbjct 924 GVAVTHSNVTQLLESIDAQLDVGQVWTQCHSLAFDFSVWEVFGALLHGGRLVVVPDDVVR 983 Query 1708 SPNDFHGLLVAEHVSVLTQTPAAV-------AMLPTQG--LESVALVVAGEACPAALVDR 1758 SP+D LLV E VSVL+QTP+A A+ P G L+ +V GEA + Sbjct 984 SPDDLRALLVREQVSVLSQTPSAFYALQSADALAPELGEQLKLQTVVFGGEALEPRRLST 1043 Query 1759 W---APGRV-MLNAYGPTETTICAAISAPLRP--GSGMPPIGVPVSGAALFVLDSWLRPV 1812 W PG M+N YG TETT+ A+ LR + + PIGVP+ A FV D WLRPV Sbjct 1044 WLHHHPGLPRMINMYGITETTVHASFREILRGDVDNNVSPIGVPLGNLAFFVFDGWLRPV 1103 Query 1813 PAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFL 1872 P GV GELY+AG G+ GY R GL+ASRFVACPFG GARMYRTGDLV W ADGQL+++ Sbjct 1104 PVGVVGELYVAGGGLATGYVGRPGLSASRFVACPFGAPGARMYRTGDLVRWSADGQLQYI 1163 Query 1873 GRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDP 1932 GR D+QVKIRGYRIELGE+ ALA++ GV QA V+ REDR GDKRLVGY T GA DP Sbjct 1164 GRADEQVKIRGYRIELGEIRAALADVEGVEQAAVLVREDRAGDKRLVGYVT----GAADP 1219 Query 1933 AGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKT 1992 + +RA+L +RLP Y+VPAAVVV+D LPLTVNGKLD RALPAPEY D + YRAPA +E+ Sbjct 1220 SEIRARLGRRLPTYMVPAAVVVLDVLPLTVNGKLDTRALPAPEYSDVDRYRAPASAIEEI 1279 Query 1993 VAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLS 2052 +AGI+A+VLG+ERVGVDDSFF+LGGDSL+AMR+IAA+N L+A + VRAL + L+ Sbjct 1280 LAGIYAQVLGVERVGVDDSFFDLGGDSLSAMRLIAAVNAALDAGVSVRALFEVPTVAQLA 1339 Query 2053 QLLGRDA 2059 L A Sbjct 1340 PRLDEGA 1346 Score = 541 bits (1395), Expect = 5e-151, Method: Compositional matrix adjust. Identities = 371/829 (45%), Positives = 469/829 (57%), Gaps = 63/829 (7%) Query 1023 IPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPA 1082 +PL+ Q+ L F Q VY + + + LRG LD + L AV + V RH +L F + Sbjct 3928 LPLTPLQQGLLFHSTTQPDGDVYAVQLTITLRGGLDPQRLHHAVQNAVARHPNLAARFCS 3987 Query 1083 VDGVPRQLV-----IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTW 1137 G P Q++ I R +L D D R+ A A R DL + PLR Sbjct 3988 GFGDPVQIIPVTPEIAYRHVELDGDADDIDD-QVRRMSAAERAAVR---DLDDQPPLRAT 4043 Query 1138 LFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLW 1197 L R AD E V HHI DGWS+ L ++ A Y R P P Y + W Sbjct 4044 LIRTADQEFRFVLTVHHIVMDGWSLPILLQEIFACY---YGSRLPAAPP----YRRFVTW 4096 Query 1198 ---------QREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGAS 1248 + LD D+P AL G R L RGA+ Sbjct 4097 LAARDAPAARAAWRDALDGFDTP----------ALVGPAGRAEL----------GPRGAA 4136 Query 1249 LVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSD--PA 1306 V A + +AR T V+ A A LL L+G DVA G ++GR P Sbjct 4137 -AVRLSAETTGALGELARSCRTTLNTVLQAAWAQLLMSLTGRHDVAFGTAVSGRPAELPG 4195 Query 1307 LDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALT 1366 +++VG +NT+ +R + AE L +++ E+Q + + R Sbjct 4196 AESMVGLLINTVPVRAQATATTTVAEFLDRLQRAHNDTVEHQHLALNEI------HRVTG 4249 Query 1367 HHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLV-FSLAERFSEGSEPAGIGG 1425 H L +L +++ P+ L T D + L+ + G E + Sbjct 4250 HDQLFDTLLVYENYPIDAAALSAADDL---TATEFTSHDYNHYPLSLQAVPGDE---LRL 4303 Query 1426 AVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLT 1485 +E+ TDVFE A+D L +RLR++L A+ A P+R + S+DALD ERA+L WGN+AVL Sbjct 4304 RIEFDTDVFEPAAVDALADRLRRLLTAMPADPDRPLRSLDALDAPERAQLQLWGNQAVLA 4363 Query 1486 APAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECV 1545 A + +S+P + AAQV+R+P+A AV SMTYRELDEASNRLAHRL GAGPGECV Sbjct 4364 AESSAALSLPALFAAQVSRVPDAGAVTFEGRSMTYRELDEASNRLAHRLIERGAGPGECV 4423 Query 1546 ALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAG 1605 ALLF R A A+VA++A LK GAAYLPIDPA P R+ FMLGDA PVAAV AGLR+RL G Sbjct 4424 ALLFPRSAEAIVAILATLKAGAAYLPIDPALPAARLEFMLGDATPVAAVAAAGLRARLDG 4483 Query 1606 HDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPA 1665 DLP++D +A P P P PA N+AY++YTSGTTG PKGV +THRNVT+L SL A Sbjct 4484 FDLPVLDAGEA-DVGPAGPLPAPAPENIAYVIYTSGTTGVPKGVAVTHRNVTQLLESLHA 4542 Query 1666 RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLT 1725 L A VWSQCHSYGFD S EIWGAL GGRLV+VPESV SP++ H LL AE VSVL+ Sbjct 4543 PLPEAGVWSQCHSYGFDVSVQEIWGALACGGRLVVVPESVTRSPDELHALLAAERVSVLS 4602 Query 1726 QTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLR 1785 TP+A+ L + L S AL++ GE CPAAL D+WAPGRVM+NAYGPTETT+ A +SAPL Sbjct 4603 HTPSALTALSPRKLRS-ALIIGGEPCPAALADQWAPGRVMINAYGPTETTVDATLSAPLT 4661 Query 1786 PGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRR 1834 G+G PP+G PV GAALFVLD WLRPVPAG GELY+AG GV VGY RR Sbjct 4662 AGAGAPPLGSPVPGAALFVLDDWLRPVPAGAVGELYVAGRGVAVGYPRR 4710 Score = 365 bits (937), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 199/350 (57%), Positives = 241/350 (69%), Gaps = 28/350 (8%) Query 1787 GSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACP 1846 GSG PPIG PVS AA FVLD WLRPVPAGV GELY+AG GVGVGYWRR GLTASRF+ACP Sbjct 4 GSGFPPIGSPVSWAAFFVLDEWLRPVPAGVVGELYLAGEGVGVGYWRRPGLTASRFMACP 63 Query 1847 FGGSGARMYRTGDLVCW----RADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVG 1902 FG G RMYRTGDLVCW +GQL++LGR D+QVK+RGYRIELGE+ AL E+ GV Sbjct 64 FGEPGTRMYRTGDLVCWGRSGSGEGQLQYLGRADEQVKVRGYRIELGEIRAALLEVEGVE 123 Query 1903 QAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTV 1962 A V+ REDR G+KRLVGY T GA DP +RA+L +RLP Y+VP+AVV +DALP+TV Sbjct 124 HAAVLVREDRAGEKRLVGYVT----GAADPTDIRARLGRRLPTYMVPSAVVALDALPMTV 179 Query 1963 NGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAA 2022 NGKLD RALPAP+Y NGYRAP +E+ +AGIFARVLG+ERVG+DDSFF LGGDSL+A Sbjct 180 NGKLDTRALPAPDYQGGNGYRAPESAIEEILAGIFARVLGVERVGIDDSFFHLGGDSLSA 239 Query 2023 MRVIAAINTTLNADLPVRALLHASSTRGLS-------QLLGR---DARPTSDPR------ 2066 MR+++A+NT L+A L VR L + + L+ L R RP P Sbjct 240 MRLVSAVNTGLDAHLGVRTLFESPTVAELAPRVCGGGSTLARVVAAERPAVVPLSFAQSR 299 Query 2067 ---LVSVHGDNPTEVHASDLTLDRFIDADTLATAV-NLPGPSPELRTVLL 2112 L +HG +P + L L +D D + TA+ ++ LRTV + Sbjct 300 LWFLDQLHGPSPVHNMSVALRLRGPLDPDAMGTALGDVVARHESLRTVFV 349 Score = 95.9 bits (237), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 206/812 (26%), Positives = 309/812 (39%), Gaps = 129/812 (15%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L+ GAAPG + + + I ++A G Y D A + +T+ Sbjct 2925 LIGCGAAPGQRVAVAMPRSAEAIVAILAVLKTGAAYVPIDPALPTARIEFMLTDAEPIAA 2984 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATK------------TAYIMPTSG 582 VT +V A GH ++D D LAT+ AY++ TSG Sbjct 2985 VTTAEVRPRLGAFAGH-----IID------VDDPALATQPATGLPDPSPDDIAYVIYTSG 3033 Query 583 TTGQPKLVRISHGSLAVFCDAISRAYG----WGAHDTVLQCAPLTSDISVEEIFGGAACG 638 TTG PK V ++H ++ ++ WG C D SV EIFG G Sbjct 3034 TTGVPKGVAVTHHNVTQLLRSVDAQLDLGRVWG------HCHSPAFDFSVWEIFGALLRG 3087 Query 639 ARLVRSAAMKTG---DLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQI 695 RLV G DL AL+ + R T + P+AV L D++ + Sbjct 3088 GRLVVVPDDIVGSPEDLHALL--IAERVTVLSQTPSAVAALSPHGLDSV---------AL 3136 Query 696 VIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGR 755 V+GGE +D+W + G +++ YGPTE T+ A + T A + +G Sbjct 3137 VVGGEPCPVEVMDRW-----APGRVMVNQYGPTETTMYAA----MTAPLTAGSAPVPIGS 3187 Query 756 PILPNTVFL-----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGSRRRAF 802 P+ +F+ GE+ I G VA GYLG A G+ R + Sbjct 3188 PVPGAALFVLDRWLRAVPPGVVGELYIAGRGVAAGYLGRAALTASRFVACPFGGNGTRMY 3247 Query 803 ATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGV 862 TGD V +G + GR D VKI G R+++ E+ +AE V AV + Sbjct 3248 RTGDVVRWGRDGQLEYLGRADEQVKIRGHRIELGEIRSALAELDGVEQAAVIARNDPAAA 3307 Query 863 WFKSQRTREGEQDAAAATRIRLV--LVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQ 920 T G D + TR RL L S V S VV + +P NGK+D+ LP P Sbjct 3308 RLVGYVT--GTADPSE-TRARLAERLPSYMVPSAVVV-LDALPLTANGKLDTRALP-APD 3362 Query 921 WSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW 979 + A L+ I+++ LG + +G D S G S+ ++++ R G Sbjct 3363 YQGGNGYRAPENAIEQILAGIYAQVLGVQRVGVDDSFFDLGGDSILSMQVVARAR-AAGV 3421 Query 980 RLSLLDLIGADTAANLADYAPTPDAPTGEDR-----FRPLVAAQRPAAIPLSFAQRRLWF 1034 D+ + A LA TGED P+VA P+ + + Sbjct 3422 MCRPRDVFVEQSVARLARVVTLA---TGEDDVVDEGIGPVVAT------PI------MRW 3466 Query 1035 LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDG-------VP 1087 L + P +N + L + + + ++ RH +LR DG VP Sbjct 3467 LRDMDGPIEQFNQTMVLAAPAGVGQADVAVVLQALLDRHPTLRLCVDD-DGAGGWDIHVP 3525 Query 1088 RQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHV 1147 ++AR VDA + + A+ A A + W A + Sbjct 3526 EAGSVDARAC---LRTVDALS------EEALMRARARLNPGAGVLVCAVW----ASATNQ 3572 Query 1148 LVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDD 1207 L + HH+A DG S L DL+ A+A G+ + LP + W + D Sbjct 3573 LALIVHHLAVDGVSWRTLIEDLNIAWAQHHRGQPIE---LPAPGTSFARWSSLLAQHAKD 3629 Query 1208 SDSPIAAQLA-YWENALAGMPERLRLPTARPY 1238 P +LA W P LP A+P+ Sbjct 3630 ---PAVTELAEVWRRITETPPA---LPPAQPW 3655 Score = 70.5 bits (171), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 93/329 (29%), Positives = 138/329 (42%), Gaps = 56/329 (17%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L++RGA PG+ + + + I ++A AG Y D A + R + GD Sbjct 4412 LIERGAGPGECVALLFPRSAEAIVAILATLKAGAAYLPIDPALP-AARLEFML--GDATP 4468 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLAT----KTAYIMPTSGTTGQPKLV 590 V V A + + G D V+D V L AY++ TSGTTG PK V Sbjct 4469 VAAVAAAGLRARLDGFD--LPVLDAGEADVGPAGPLPAPAPENIAYVIYTSGTTGVPKGV 4526 Query 591 RISHGSLAVFCDAIS----RAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---R 643 ++H ++ +++ A W QC D+SV+EI+G ACG RLV Sbjct 4527 AVTHRNVTQLLESLHAPLPEAGVWS------QCHSYGFDVSVQEIWGALACGGRLVVVPE 4580 Query 644 SAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQ-IVIGGEAI 702 S +L AL L A ++ L A+ A+ +LR ++IGGE Sbjct 4581 SVTRSPDELHAL---LAAERVSV----------LSHTPSALTALSPRKLRSALIIGGEPC 4627 Query 703 RCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTV 762 + D+W + G ++++YGPTE TV AT T LG P+ + Sbjct 4628 PAALADQW-----APGRVMINAYGPTETTVDATL----SAPLTAGAGAPPLGSPVPGAAL 4678 Query 763 FL-----------AFGEVVIVGDLVADGY 780 F+ A GE+ + G VA GY Sbjct 4679 FVLDDWLRPVPAGAVGELYVAGRGVAVGY 4707 >gi|169631764|ref|YP_001705413.1| non-ribosomal peptide synthetase PstA [Mycobacterium abscessus ATCC 19977] gi|169243731|emb|CAM64759.1| Probable non-ribosomal peptide synthetase PstA [Mycobacterium abscessus] Length=8108 Score = 1376 bits (3561), Expect = 0.0, Method: Compositional matrix adjust. Identities = 800/1504 (54%), Positives = 972/1504 (65%), Gaps = 98/1504 (6%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AYI+ TSGTTG PK V I+H ++ S A H T Q D SVEEI+G Sbjct 5718 AYIIYTSGTTGVPKGVAIAHHNVTALMG--SPATFLAGH-TWAQWHSYAFDASVEEIWGS 5774 Query 635 AACGARLV---RSAAMKTGDLAALVDDLVARETT-IVDLPTAVWQLLCADGDAIDAIGRS 690 G RLV SAA L AL LVA + T + P+AV L DA+ Sbjct 5775 LLHGGRLVVVPESAAHSPEHLTAL---LVAEQVTALSQTPSAVALLTPESLDAV------ 5825 Query 691 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQT------ 744 +++ GE VD+W + G ++++YGPTE T+ A+ + T Sbjct 5826 ---SLLVAGEPCPGEVVDRW-----APGRLMVNAYGPTETTICASRTAALVGGTGSPSIG 5877 Query 745 ---------TMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDG---DGFGTVT 792 +DG L RP+ P V GE+ I G V GY G G F Sbjct 5878 APVPGAAMFVLDGLL----RPVPPGVV----GELYIAGHGVGVGYAGRTGLTASRFVACP 5929 Query 793 AADGSR--RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSD 850 AD +R + TGD V A+G + GR D VKI G R+++AE+ + V Sbjct 5930 FADAQLPGQRMYRTGDLVRWRADGQLEYLGRADEQVKIRGYRIELAEIHSVLTALDGVDQ 5989 Query 851 VAVELHSGSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKP 906 AV G V + + + A A ++ +V + V + + Sbjct 5990 AAVIAREDRPGDRRLVGYVTGTANPAKLRAQLAEQLPAYMVPVAVVVLAALPM-----TV 6044 Query 907 NGKIDSDNLPR-----LPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEG 960 NGK+D+ LPR + ++ A G T E L+ I++R LG +G D S G Sbjct 6045 NGKLDTRALPRPEYQDIDRYRAPGTLTEEI------LAGIYARVLGVERVGVDDSFFDLG 6098 Query 961 IGSLDLIRILPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP 1020 SL +R++ L +S+ + A T LA P PLVAA+RP Sbjct 6099 GDSLSAMRLIAAVNADLNAVVSVRTVFEAPTVGQLA-----PRIADASSSLSPLVAAERP 6153 Query 1021 AAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 A IPLSFAQ RLWFLDQLQ P+PVYNMA ALR+ G LD +ALGA +ADVV RHESLRT F Sbjct 6154 AQIPLSFAQARLWFLDQLQGPSPVYNMATALRISGALDVDALGAGLADVVARHESLRTQF 6213 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFR 1140 A GVP+Q+V+ A A G D+VDAT W +L+ AI EAARH+FDL+ EIPL LFR Sbjct 6214 RATGGVPQQVVVPAADAHFGWDVVDATGWTTSQLREAIGEAARHTFDLSNEIPLYARLFR 6273 Query 1141 IADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQRE 1200 I DE+VL AV HHIAAD WS+ PL DL AY SR AG AP WAPL VQYVDYTLWQR Sbjct 6274 ITGDEYVLAAVVHHIAADAWSITPLVTDLGVAYVSRRAGHAPGWAPLAVQYVDYTLWQRA 6333 Query 1201 ILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQ 1260 GD D S IAAQL YW++ALAGMPER+ LPT RPYP ADQRG+++ V WPA++Q+Q Sbjct 6334 EFGDFADGGSRIAAQLDYWQDALAGMPERVELPTDRPYPSTADQRGSTMAVQWPAALQEQ 6393 Query 1261 VRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL 1320 + R+AR+HNATSFMV+ A L VLLSKLSG+ DVAVGFPIAGR DPALD L+GFFVNTLVL Sbjct 6394 IARVAREHNATSFMVLQAALGVLLSKLSGNTDVAVGFPIAGRRDPALDELIGFFVNTLVL 6453 Query 1321 RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN 1380 R++L+GDP+ AELL QVRARSLAAYENQDVPFEVLV+RL PTR+LTHHPLIQV L WQ+ Sbjct 6454 RLDLSGDPTVAELLAQVRARSLAAYENQDVPFEVLVERLNPTRSLTHHPLIQVALGWQNV 6513 Query 1381 PVGQLN--------LGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTD 1432 P GQ N LGDL+ TPM DT+TARMDL FSLAE + EPAGIGG VE+RTD Sbjct 6514 P-GQDNGSSGPGLALGDLEVTPMDADTQTARMDLSFSLAEHRTRDGEPAGIGGTVEFRTD 6572 Query 1433 VFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPV 1492 VF+ +I+ L+ R VL A+ A E +SSID LD E ARLD GNRA+L A PV Sbjct 6573 VFDPASIERLLGRFELVLTAMTADVESRLSSIDVLDPAEHARLDSMGNRALLEQRAINPV 6632 Query 1493 SIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERC 1552 ++P + A QVAR PEA AV CG ++TYRELD+A+N LA RL+ G PG CVALL ER Sbjct 6633 TVPALFADQVARTPEAVAVTCGGHALTYRELDDAANWLALRLSRAGVVPGGCVALLLERS 6692 Query 1553 APAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIID 1612 + A+VAM+AVLK GAAYL IDP P R+ FML DA P A VTT+GL R G ++ +ID Sbjct 6693 SQAIVAMLAVLKAGAAYLAIDPVMPSARIDFMLDDAAPTAVVTTSGLAGRFDGREMSVID 6752 Query 1613 V-----VD----ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASL 1663 + VD + P P P P ++AY++YTSGTTG PKGV +TH N+T L S Sbjct 6753 IGELADVDDAEMEIVHSPANPGPEPD--DIAYLIYTSGTTGVPKGVAVTHHNLTHLARST 6810 Query 1664 PARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSV 1723 PA+L A QVW+QCHSY FD S WEIW ALLGG R+V+VPES+ +SP DFH LLV E V+V Sbjct 6811 PAQLPANQVWTQCHSYAFDFSVWEIWAALLGGARVVVVPESIVSSPEDFHTLLVRERVNV 6870 Query 1724 LTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAP 1783 LTQTP+A L GL+SVAL++ GEACP +VDRWA G ++NAYGPTE T+ A++SAP Sbjct 6871 LTQTPSAAGALSPAGLDSVALLLGGEACPGEVVDRWAAGHTVINAYGPTEITVYASMSAP 6930 Query 1784 LRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFV 1843 L GSG PIG PVS +ALFVLD WLRPVP GV GELY+AG GV GY R+GLT++RFV Sbjct 6931 LAAGSGAAPIGAPVSTSALFVLDEWLRPVPVGVVGELYVAGEGVACGYLGRSGLTSARFV 6990 Query 1844 ACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQ 1903 ACPFG GARMYRTGDLV WR DGQL++ GR DDQVKIRGYRIELGEV AL+ L+ V Q Sbjct 6991 ACPFGVPGARMYRTGDLVSWRPDGQLQYRGRADDQVKIRGYRIELGEVQAALSALSDVSQ 7050 Query 1904 AVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVN 1963 A VIARED PG RLVGY TE G +P LR LA R+PGY+VP+A+VV++ALPLTVN Sbjct 7051 AAVIAREDPPGVTRLVGYVTESVNGVAEPDRLRNALANRVPGYMVPSAIVVLEALPLTVN 7110 Query 1964 GKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAM 2023 GKLD RALPAPEY D YRAPA VE+T+AGI+A+VLGL+RVGVDDSFF+LGGDS+ +M Sbjct 7111 GKLDIRALPAPEYQDAERYRAPADAVEETLAGIYAQVLGLDRVGVDDSFFDLGGDSILSM 7170 Query 2024 RVIA 2027 +V+A Sbjct 7171 QVVA 7174 Score = 1309 bits (3388), Expect = 0.0, Method: Compositional matrix adjust. Identities = 820/1636 (51%), Positives = 1017/1636 (63%), Gaps = 116/1636 (7%) Query 474 WLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY--------------SVCDTADEI 519 +L+ RG PG+ + + + + ++A G Y V D Sbjct 4558 FLIGRGVGPGERVALMFPRSAEAVVAILAVLKTGAAYLPIDPALPGARVEFMVSDAGPMA 4617 Query 520 SVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKTAYIMP 579 V T A+ E G + VVDV +A L T + D + A+I+ Sbjct 4618 VVTTAALAERFSGFGLPVVDVQDPAIAAECGAGL--------TMPSADGM-----AHIIY 4664 Query 580 TSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGA 639 TSGTTG PK V ++ ++ D++ Q + D SV EI+G G Sbjct 4665 TSGTTGLPKGVAVTQRNVTQLFDSLQIGVPLEPGQVWTQFHSYSFDFSVWEIWGALLHGG 4724 Query 640 RLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIV 696 RLV + A + D L LV + T++ + +L DG +D + +V Sbjct 4725 RLVVVPETIARSSRDFHRL---LVREQVTVLTQTPSAVSMLPVDG--LD------VATLV 4773 Query 697 IGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRP 756 IG E VD+W + G ++++ YGPTE T+ +C + L P Sbjct 4774 IGAEPCSPELVDRW-----APGRTMVNVYGPTETTM------WLCASAPLAPGLG--APP 4820 Query 757 ILPNTVFLAFGEV-----VIVGDLVADGYLGIDGDGFGT-----VTAAD---------GS 797 I T + AF + + +V + YLG G G G +TAA GS Sbjct 4821 IGSPTAWAAFFVLDEWLRPVPAGVVGELYLGGAGVGIGYWRRSGLTAARFMACPFGEPGS 4880 Query 798 RRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHS 857 R + TGD V A+G + GR D VKI G R+++ E+ +A V + AV Sbjct 4881 R--MYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEIQSALAALDGVENAAVIARE 4938 Query 858 GSLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSD 913 G V + + A A R+ +V V VG+ +P NGK+D Sbjct 4939 DRPGDKRLVGYITGAADPVGARTALAERLPGYMVPAAV-----VGLAALPMTVNGKLDVR 4993 Query 914 NLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPE 972 LP P + A G L+ I++R L +G D S G S+ +R++ Sbjct 4994 ALPA-PDYQDVDRYRAPVGAVQEILAGIYARVLDVERVGVDDSFFDLGGDSVSTMRLVAA 5052 Query 973 TRRYLGWRLSLLDLIGADTAANLA----DYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFA 1028 L LS + A T A LA + A P+ PLV +RP IPLSFA Sbjct 5053 VNAALNADLSTRTVFDAPTIAQLALRIGEGAGGPE---------PLVVVERPEVIPLSFA 5103 Query 1029 QRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPR 1088 Q RLWF+DQLQ P+PVYNM V LRL G LD ALGAA++D++GRHESLRT F A G PR Sbjct 5104 QNRLWFVDQLQGPSPVYNMPVGLRLYGRLDAAALGAALSDLIGRHESLRTRFDAPGGNPR 5163 Query 1089 QLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVL 1148 Q+V+ D G +I+DAT+W +L AI SFDLA EIPL +FRIA++EHVL Sbjct 5164 QIVLPDGPIDFGWEIIDATSWQTGQLDEAIAATVCRSFDLAIEIPLYARVFRIAEEEHVL 5223 Query 1149 VAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDS 1208 VAV HHIAADGWS+ PL DLS AYASRC G APDWAPLPVQYVDYTLWQR LGDL D Sbjct 5224 VAVVHHIAADGWSLTPLMHDLSVAYASRCRGHAPDWAPLPVQYVDYTLWQRAQLGDLGDG 5283 Query 1209 DSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQH 1268 DSPI+AQLAYWE ALAG+PER+ LPT RPYPPVADQRG+++ V WP +QQQVR AR+H Sbjct 5284 DSPISAQLAYWEGALAGLPERVALPTDRPYPPVADQRGSTVEVQWPPELQQQVRATAREH 5343 Query 1269 NATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDP 1328 ATSFMV+ A LAVLL+ +SG+ DVAVGFPIAGR D ALD LVGFFVN LVLRV+L+GDP Sbjct 5344 GATSFMVMQASLAVLLASISGTSDVAVGFPIAGRRDTALDQLVGFFVNNLVLRVDLSGDP 5403 Query 1329 SFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQD------NPV 1382 + AELL QVR RSLAAYENQDVPFEVLV+RL P R+L HHPL+QV LAWQ+ P Sbjct 5404 TVAELLTQVRQRSLAAYENQDVPFEVLVERLNPIRSLAHHPLVQVALAWQNLPWQDTGPA 5463 Query 1383 GQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVL 1442 L LGDL+ P+ +DT+TARMDL FSL ER++ EPAGI GAVE+RTDVF+A +I+ L Sbjct 5464 DGLRLGDLRVEPLSVDTQTARMDLTFSLGERWTMAGEPAGIAGAVEFRTDVFDADSIEAL 5523 Query 1443 IERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQV 1502 I R ++V+ ++ A P R +SSID LD E R+D WGNR +L P S+P + A Q Sbjct 5524 IARWQRVVASMTADPSRRLSSIDVLDEAEHTRVDRWGNRELLNRPPAVRRSVPALFAEQA 5583 Query 1503 ARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAV 1562 AR+P A A+ +TYRE+D+AS++LAHRL G PGE VALL ERC AVVAM+AV Sbjct 5584 ARVPHAVAISFNGRELTYREVDQASDQLAHRLIAQGVRPGESVALLTERCPEAVVAMLAV 5643 Query 1563 LKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD---ALAA 1619 LKTGAAYLPIDPA P RV FM+GDA P AA+TTA L RLAG+ L +IDV D ++ Sbjct 5644 LKTGAAYLPIDPALPDVRVEFMIGDAAPTAAITTADLTDRLAGYALTVIDVGDIAEGASS 5703 Query 1620 YPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSY 1679 G+ P+P+ ++AYI+YTSGTTG PKGV I H NVT L S PA A W+Q HSY Sbjct 5704 GAGSSLPLPSPDDIAYIIYTSGTTGVPKGVAIAHHNVTALMGS-PATFLAGHTWAQWHSY 5762 Query 1680 GFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGL 1739 FDAS EIWG+LL GGRLV+VPES A SP LLVAE V+ L+QTP+AVA+L + L Sbjct 5763 AFDASVEEIWGSLLHGGRLVVVPESAAHSPEHLTALLVAEQVTALSQTPSAVALLTPESL 5822 Query 1740 ESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSG 1799 ++V+L+VAGE CP +VDRWAPGR+M+NAYGPTETTICA+ +A L G+G P IG PV G Sbjct 5823 DAVSLLVAGEPCPGEVVDRWAPGRLMVNAYGPTETTICASRTAALVGGTGSPSIGAPVPG 5882 Query 1800 AALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGS---GARMYR 1856 AA+FVLD LRPVP GV GELYIAG GVGVGY R GLTASRFVACPF + G RMYR Sbjct 5883 AAMFVLDGLLRPVPPGVVGELYIAGHGVGVGYAGRTGLTASRFVACPFADAQLPGQRMYR 5942 Query 1857 TGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDK 1916 TGDLV WRADGQLE+LGR D+QVKIRGYRIEL E+ + L L GV QA VIAREDRPGD+ Sbjct 5943 TGDLVRWRADGQLEYLGRADEQVKIRGYRIELAEIHSVLTALDGVDQAAVIAREDRPGDR 6002 Query 1917 RLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEY 1976 RLVGY T G +PA LRAQLA++LP Y+VP AVVV+ ALP+TVNGKLD RALP PEY Sbjct 6003 RLVGYVT----GTANPAKLRAQLAEQLPAYMVPVAVVVLAALPMTVNGKLDTRALPRPEY 6058 Query 1977 GDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNAD 2036 D + YRAP E+ +AGI+ARVLG+ERVGVDDSFF+LGGDSL+AMR+IAA+N LNA Sbjct 6059 QDIDRYRAPGTLTEEILAGIYARVLGVERVGVDDSFFDLGGDSLSAMRLIAAVNADLNAV 6118 Query 2037 LPVRALLHASSTRGLS 2052 + VR + A + L+ Sbjct 6119 VSVRTVFEAPTVGQLA 6134 Score = 1295 bits (3352), Expect = 0.0, Method: Compositional matrix adjust. Identities = 762/1487 (52%), Positives = 948/1487 (64%), Gaps = 73/1487 (4%) Query 575 AYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGG 634 AYI+ TSGTTG PK V I+H ++ DA++ G Q + D+SV EIFG Sbjct 2110 AYIIFTSGTTGTPKGVAIAHRNVPGLFDALNAQVPSGTGQVWAQWHSYSFDVSVWEIFGA 2169 Query 635 ---AACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSR 691 AC + AA G+L L LV + +++ + ++ G A+ Sbjct 2170 LLHGACLLVVTEQAAASPGELHEL---LVTQRVSVLSQTPSAAGMISPQGLESTAL---- 2222 Query 692 LRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATF-LPIVCDQTTMDGA- 749 V+ GEA VD+W + G ++++YGPTEATV A+ P+ + GA Sbjct 2223 ----VVAGEACPPELVDRW-----APGRVMVNAYGPTEATVYASISAPLQSGSPVLIGAP 2273 Query 750 --------LLRLGRPILPNTVFLAFGEVVIVGDLVADGY---LGIDGDGFGTVTAADGSR 798 L + RP P GE+ + G V GY G+ F + Sbjct 2274 VPGVALFVLDQWMRPAPPGVA----GELYVAGRGVGLGYWRRTGLTSTRFVACPFGEPGG 2329 Query 799 RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSG 858 R + TGD V D G + GR D VKI G R+++ EV +A V+ V H Sbjct 2330 R-MYRTGDLVQWDDGGQLRYLGRADEQVKIRGYRIELGEVQAALATLDGVTQAVVIAHED 2388 Query 859 SLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKIDSDNL 915 G + G+ D RIR L + VV + +P +GK+D L Sbjct 2389 QGGT-LRLVGYVVGKADP---DRIRTQLAARLPGYMVPAAVVVIDALPLTVSGKLDRRAL 2444 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRA-IGPDSSLLGEGIGSLDLIRILPETR 974 P P + A A + L+ I++R LG +G D S G SL +R+L Sbjct 2445 PA-PDYVDAARYRAPSNPTEEILTDIYARVLGHERVGIDDSFFDLGGDSLSAMRLLAGIN 2503 Query 975 RYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWF 1034 L +++ L A T A L E R PL A +RPA +PLSFAQ RLWF Sbjct 2504 AALNTGVTVRTLFDAPTVAQLCTRISR-----DETRVAPLTARERPARVPLSFAQSRLWF 2558 Query 1035 LDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEA 1094 LDQLQ P+ +YNM A R+ G LD +AL AA DVV RHESLRT+F A DGVP Q+V+ A Sbjct 2559 LDQLQGPSAIYNMTAAFRIDGELDADALAAAFTDVVARHESLRTLFEAPDGVPHQMVMPA 2618 Query 1095 RRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHH 1154 A+ G +++DA W +L+ AI+E +RH+FDL+ EIPL+ LFR+ D+EH LV V HH Sbjct 2619 GGAEPGWEVIDAGDWSVGQLREAIDEISRHAFDLSAEIPLKAALFRVTDNEHALVVVVHH 2678 Query 1155 IAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAA 1214 IAADGWS+APL ADL AYASRCAG AP WA LPVQY DY+LWQR G+L DSDSPIA Sbjct 2679 IAADGWSIAPLMADLGTAYASRCAGEAPAWADLPVQYADYSLWQRAQFGELQDSDSPIAR 2738 Query 1215 QLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFM 1274 QL YW ALAG+PER+ LPT RPYP ADQRGA++ V+WP +Q+Q+ +A ++NATSFM Sbjct 2739 QLRYWHGALAGLPERITLPTDRPYPLAADQRGATIAVNWPVELQRQIAELAAENNATSFM 2798 Query 1275 VVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 VV A L +LLS+LS + DVAVGFPIAGR DPALD LVGFFVNTLVLR +LAG+P+ E+L Sbjct 2799 VVQAALLILLSRLSANSDVAVGFPIAGRRDPALDQLVGFFVNTLVLRADLAGNPTICEVL 2858 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ-------DNPVGQLNL 1387 QVR RSL A++NQDVPFEVLVDRL P R+L HHP++QV LAWQ ++ + L Sbjct 2859 EQVRVRSLEAFDNQDVPFEVLVDRLNPVRSLAHHPVVQVALAWQNFAGRHVNDSAAGVEL 2918 Query 1388 GDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLR 1447 GDL+ + MP++TRTARMD+ FSLAER+++ EPAGIGG VE+RTDVF+A+ I L+ RL+ Sbjct 2919 GDLRISQMPVETRTARMDVNFSLAERWTKSGEPAGIGGTVEFRTDVFDARTIQSLVTRLQ 2978 Query 1448 KVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPE 1507 +VL A+ A P +S +D LD ER RL GN A L P S+ + A +V+R PE Sbjct 2979 RVLTAITANPAARLSVVDLLDDDERCRLSVLGNHATLARTPSRPASVTGLFAEKVSRTPE 3038 Query 1508 AEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGA 1567 A AV CG+ S TYRELD A+NRLAH L GAGPG+ VALL R A A+ A++ +LKTGA Sbjct 3039 AVAVSCGERSWTYRELDSAANRLAHLLIDQGAGPGQVVALLSNRSAEAIAAILGILKTGA 3098 Query 1568 AYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYP------ 1621 AYLPIDPA P R+ F+L DA PV AVTT L RL G L IID + + +P Sbjct 3099 AYLPIDPAVPDARLTFVLADAGPVVAVTTTDLADRLDGRGLAIID-IRGVGPHPPDAGFD 3157 Query 1622 -GTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYG 1680 P P P + AY++YTSGTTG PKGV ++HRNVT+L SL A L VWS HS Sbjct 3158 GAIPDPEPD--HTAYLIYTSGTTGVPKGVALSHRNVTQLLDSLDAGLPHPGVWSHSHSLA 3215 Query 1681 FDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLE 1740 FD S WEI+GALL GGR+VI E +SP D H LL+ EHV+V+TQTP+A LP +GL+ Sbjct 3216 FDVSVWEIFGALLSGGRVVIASEGATSSPEDLHALLIREHVTVITQTPSAARALPREGLD 3275 Query 1741 SVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGA 1800 S ALVV GEACPA +VD+WAPGRVM+NAYGPTETT+C AISAPL G G+ PIG PV+GA Sbjct 3276 SAALVVVGEACPAEVVDQWAPGRVMINAYGPTETTMCVAISAPLTAGQGV-PIGTPVTGA 3334 Query 1801 ALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDL 1860 ALFVLD LR VP GV GELY+AG GVG GY RA LT++RFVACPFG G RMYRTGDL Sbjct 3335 ALFVLDESLRQVPVGVVGELYVAGRGVGYGYVGRAPLTSTRFVACPFGDPGTRMYRTGDL 3394 Query 1861 VCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVG 1920 VCWR DGQL +LGR D+QVKIRG+RIEL E+ LA L GV +AVVIAREDRPGDKRLVG Sbjct 3395 VCWRPDGQLNYLGRADEQVKIRGHRIELAEIQAVLASLGGVEEAVVIAREDRPGDKRLVG 3454 Query 1921 YATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTN 1980 Y T G D GLR +A RLP Y+VPAAVV +DA+PLTVNGKLD RALPAP+YGD Sbjct 3455 YIT----GTADCGGLRMAIADRLPAYMVPAAVVRLDAIPLTVNGKLDTRALPAPDYGDHG 3510 Query 1981 GYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 YRAPA VE+ +A I+A+VLGLERV VDDSFF+LGGDS+ +M+V++ Sbjct 3511 RYRAPANAVEEVLADIYAQVLGLERVSVDDSFFDLGGDSILSMQVVS 3557 Score = 804 bits (2076), Expect = 0.0, Method: Compositional matrix adjust. Identities = 493/1029 (48%), Positives = 624/1029 (61%), Gaps = 53/1029 (5%) Query 1044 VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADLGCDI 1103 +Y + + + + G L+ E L AV V RH L F P QL+ +G Sbjct 4095 LYVVQLDITIDGALEPERLHGAVHTVAARHPHLAARFCGQFEQPVQLI--PAEPTVGWRY 4152 Query 1104 VDATA-WPA----DRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAAD 1158 VD +A W + LQR DL R L R+A + + V HHI D Sbjct 4153 VDLSAEWNCADKDEELQRLCAAERAAVCDLTEPPAFRVALIRVAAERYRFVLTNHHIVLD 4212 Query 1159 GWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAY 1218 GWS+ L ++ AAY + R P P + ++ W + AA A Sbjct 4213 GWSLPILLQEIFAAYRGQ---RLPAATP----FRNFVSWL---------AARDTAAAQAA 4256 Query 1219 WENALAGMPERLRLPT--ARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVV 1276 W LAG + PT P +RG + + +AR + T V+ Sbjct 4257 WGEVLAG----FQTPTLVGPPQKSGLGRRGVR-THQLSGRLTGALGELARAQHTTVNTVL 4311 Query 1277 AAGLAVLLSKLSGSPDVAVGFPIAGRSD--PALDNLVGFFVNTLVLRVNLAGDPSFAELL 1334 A+LL+ L+G DV G ++GR P +++VG +NT+ +R N++ + A LL Sbjct 4312 QGAWALLLTSLTGQQDVVFGSVVSGRPADVPGAESMVGLLINTVPVRANISAATTTAGLL 4371 Query 1335 GQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQ-AT 1393 Q+ E+Q VP + R L + +++ PV + G L A Sbjct 4372 DQLTKEHAKTLEHQHVPLSEI------HRIAEQERLFDTLFVFENYPV---DTGVLSGAD 4422 Query 1394 PMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAV 1453 ID + + L + G E + +EY T +F+ I+ ++R+ VL A+ Sbjct 4423 GFAIDEIISHESTDYPLTMQAIPGGE---LRLRIEYDTALFDVCGIETFVKRIESVLSAM 4479 Query 1454 AAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC 1513 A P R +S++ LD TER RL WGN+ VLT A P SIP++ A QV R P++ A+ C Sbjct 4480 VADPRRPLSAVQILDETERDRLQRWGNQGVLTHLA-QPASIPELFARQVTRSPKSIALVC 4538 Query 1514 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPID 1573 D S+TY LDEASNRLA L G G GPGE VAL+F R A AVVA++AVLKTGAAYLPID Sbjct 4539 EDRSLTYLALDEASNRLARFLIGRGVGPGERVALMFPRSAEAVVAILAVLKTGAAYLPID 4598 Query 1574 PANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVN 1632 PA P RV FM+ DA P+A VTTA L R +G LP++DV D A+AA G MP+A Sbjct 4599 PALPGARVEFMVSDAGPMAVVTTAALAERFSGFGLPVVDVQDPAIAAECGAGLTMPSADG 4658 Query 1633 LAYILYTSGTTGEPKGVGITHRNVTRLFASLP--ARLSAAQVWSQCHSYGFDASAWEIWG 1690 +A+I+YTSGTTG PKGV +T RNVT+LF SL L QVW+Q HSY FD S WEIWG Sbjct 4659 MAHIIYTSGTTGLPKGVAVTQRNVTQLFDSLQIGVPLEPGQVWTQFHSYSFDFSVWEIWG 4718 Query 1691 ALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEA 1750 ALL GGRLV+VPE++A S DFH LLV E V+VLTQTP+AV+MLP GL+ LV+ E Sbjct 4719 ALLHGGRLVVVPETIARSSRDFHRLLVREQVTVLTQTPSAVSMLPVDGLDVATLVIGAEP 4778 Query 1751 CPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLR 1810 C LVDRWAPGR M+N YGPTETT+ SAPL PG G PPIG P + AA FVLD WLR Sbjct 4779 CSPELVDRWAPGRTMVNVYGPTETTMWLCASAPLAPGLGAPPIGSPTAWAAFFVLDEWLR 4838 Query 1811 PVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLE 1870 PVPAGV GELY+ GAGVG+GYWRR+GLTA+RF+ACPFG G+RMYRTGDLV WRADGQL+ Sbjct 4839 PVPAGVVGELYLGGAGVGIGYWRRSGLTAARFMACPFGEPGSRMYRTGDLVRWRADGQLD 4898 Query 1871 FLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAV 1930 +LGR D+QVKIRGYRIELGE+ +ALA L GV A VIAREDRPGDKRLVGY T GA Sbjct 4899 YLGRADEQVKIRGYRIELGEIQSALAALDGVENAAVIAREDRPGDKRLVGYIT----GAA 4954 Query 1931 DPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVE 1990 DP G R LA+RLPGY+VPAAVV + ALP+TVNGKLD RALPAP+Y D + YRAP G V+ Sbjct 4955 DPVGARTALAERLPGYMVPAAVVGLAALPMTVNGKLDVRALPAPDYQDVDRYRAPVGAVQ 5014 Query 1991 KTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRG 2050 + +AGI+ARVL +ERVGVDDSFF+LGGDS++ MR++AA+N LNADL R + A + Sbjct 5015 EILAGIYARVLDVERVGVDDSFFDLGGDSVSTMRLVAAVNAALNADLSTRTVFDAPTIAQ 5074 Query 2051 LSQLLGRDA 2059 L+ +G A Sbjct 5075 LALRIGEGA 5083 Score = 790 bits (2040), Expect = 0.0, Method: Compositional matrix adjust. Identities = 489/1049 (47%), Positives = 622/1049 (60%), Gaps = 55/1049 (5%) Query 1023 IPLSFAQRRLWFLDQLQRPAP-VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF- 1080 +PL+ Q+ L + R VY M ++L L G LD + L AV VV RH L F Sbjct 1525 LPLTPLQQGLLYHSGTARGCDDVYAMQLSLVLDGQLDPQQLRDAVQSVVDRHPHLAARFY 1584 Query 1081 ----PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSF-DLATEIPLR 1135 P + +P V+ + L + D D + I A R + DLA +R Sbjct 1585 ERFDPPIQAIPTDPVVPWQYLALDFNGTDI-----DGQVQEISAAERVAVGDLANRCAIR 1639 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L R AD++H + HHI DGWS+ L ++ A+ + A Y + Sbjct 1640 AALIRTADEQHRFILTTHHIVLDGWSMPILIQEIFASLRGQRLRPA-------ASYRSFV 1692 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPA 1255 W L + D +AAQ A W A+AG + + P P RG P Sbjct 1693 TW-------LSERDQ-VAAQHA-WRKAMAGFDAPTLVGPSTPDGP--GHRGVE-SFQLPE 1740 Query 1256 SVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPAL--DNLVGF 1313 + + V +AR T +V+ A+LLS L G DVA G ++GR L +++VG Sbjct 1741 EITKNVGELARSRQTTVNVVLQGAWALLLSSLCGHGDVAFGTTVSGRPAEVLGAESMVGL 1800 Query 1314 FVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQV 1373 +NT+ +R + + AELLGQ++ R E+Q + + R L Sbjct 1801 LINTVPVRATIGAATTTAELLGQLQGRHNDTLEHQHLALSDI------HRITGQERLFDT 1854 Query 1374 MLAWQDNPVGQLNLGDLQATPMP-IDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTD 1432 ++ +++ P+ D++ + D R + + LA + GS +G +EY + Sbjct 1855 LMVFENYPIDVTERWDIEGLAVTGFDFRESNH---YPLAVQVLPGS---ALGLRIEYDSG 1908 Query 1433 VFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPV 1492 VF+ A+ L RL +L A+ A P +SSID LD R +LD W R L P P Sbjct 1909 VFDCAAVKALFGRLTTILSAMTADPGLPLSSIDLLDDAVRTQLDTWSGRESLIDP-PAVK 1967 Query 1493 SIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERC 1552 SIP++ QV R P A AV C S+TYRELDE++NRLA LA GAG GE VALLF R Sbjct 1968 SIPELFGEQVERSPGAIAVTCDGRSLTYRELDESANRLARVLADRGAGSGETVALLFSRS 2027 Query 1553 APAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIID 1612 A A+VAM+AVLKTGAAY+P+DPA P R+ FM+ D P+ AVTT R RL +L IID Sbjct 2028 AEAIVAMLAVLKTGAAYVPVDPALPLARIEFMVADTAPILAVTTTEHRPRLGDIELCIID 2087 Query 1613 VVD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAA- 1670 + + + T PP P ++AYI++TSGTTG PKGV I HRNV LF +L A++ + Sbjct 2088 INEPSPDVQAETAPPGPTPDDIAYIIFTSGTTGTPKGVAIAHRNVPGLFDALNAQVPSGT 2147 Query 1671 -QVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPA 1729 QVW+Q HSY FD S WEI+GALL G L++V E AASP + H LLV + VSVL+QTP+ Sbjct 2148 GQVWAQWHSYSFDVSVWEIFGALLHGACLLVVTEQAAASPGELHELLVTQRVSVLSQTPS 2207 Query 1730 AVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSG 1789 A M+ QGLES ALVVAGEACP LVDRWAPGRVM+NAYGPTE T+ A+ISAPL+ GS Sbjct 2208 AAGMISPQGLESTALVVAGEACPPELVDRWAPGRVMVNAYGPTEATVYASISAPLQSGSP 2267 Query 1790 MPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGG 1849 + IG PV G ALFVLD W+RP P GVAGELY+AG GVG+GYWRR GLT++RFVACPFG Sbjct 2268 VL-IGAPVPGVALFVLDQWMRPAPPGVAGELYVAGRGVGLGYWRRTGLTSTRFVACPFGE 2326 Query 1850 SGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAR 1909 G RMYRTGDLV W GQL +LGR D+QVKIRGYRIELGEV ALA L GV QAVVIA Sbjct 2327 PGGRMYRTGDLVQWDDGGQLRYLGRADEQVKIRGYRIELGEVQAALATLDGVTQAVVIAH 2386 Query 1910 EDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHR 1969 ED+ G RLVGY G DP +R QLA RLPGY+VPAAVVVIDALPLTV+GKLD R Sbjct 2387 EDQGGTLRLVGYVV----GKADPDRIRTQLAARLPGYMVPAAVVVIDALPLTVSGKLDRR 2442 Query 1970 ALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAI 2029 ALPAP+Y D YRAP+ P E+ + I+ARVLG ERVG+DDSFF+LGGDSL+AMR++A I Sbjct 2443 ALPAPDYVDAARYRAPSNPTEEILTDIYARVLGHERVGIDDSFFDLGGDSLSAMRLLAGI 2502 Query 2030 NTTLNADLPVRALLHASSTRGLSQLLGRD 2058 N LN + VR L A + L + RD Sbjct 2503 NAALNTGVTVRTLFDAPTVAQLCTRISRD 2531 Score = 625 bits (1611), Expect = 5e-176, Method: Compositional matrix adjust. Identities = 444/1049 (43%), Positives = 581/1049 (56%), Gaps = 86/1049 (8%) Query 1022 AIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFP 1081 A+ L+ Q +W ++ R +++ + R+ G ++ L AV V+ E LR VF Sbjct 7 ALSLTRGQLDIWLAEETGRSGAKWHLGMLGRIEGIIEHGLLEQAVRQVIHEAEPLRAVFS 66 Query 1082 AVDGVPRQLVIEARRADLGCDIVDATAWP---ADRLQRAIEEAARHSFDLATEIPLRTWL 1138 ++G Q V++ +L + + P A R+ +I++A +PL L Sbjct 67 ELNGQVFQTVVDYPDTELAHHDLTGSPDPVGDAYRIAGSIQKA---------PMPLDGPL 117 Query 1139 FRIA-----DDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVD 1193 FR A D+ HHI DG + L ++A Y S A AP P P+ Sbjct 118 FRFALMQVRPDDFYFFVCCHHIVTDGIGMGLLCHRIAAVY-SAIATDAP--VPAPIFGSL 174 Query 1194 YTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGA----SL 1249 +L + E D + S+ + AYW + + + LR T PP A R A S Sbjct 175 RSLVESE--SDYEGSEDYLD-DAAYWASC-GPLDDELRYGT----PPAAAARLAEYEPSA 226 Query 1250 VVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDN 1309 + +V + R ++ V+ A A+L+ G +V + FP++ R P Sbjct 227 PIQLDPAVVAKARELSHALGVRRAAVITAACALLVHGEVGGAEVVLDFPVSRRVRPEALL 286 Query 1310 LVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRA--LTH 1367 + G + LR+ + S A+ V R A +Q P + + R + Sbjct 287 VPGMSSGVVPLRLTTSPYTSVADFCEHVATRIQEALRHQRFPLRDIESKTGFQRGGWPSR 346 Query 1368 HPLIQVMLAWQDNPVGQLNLGDLQ-ATPMPIDTRTARMD---LVF--SLAERFSEGSEPA 1421 H + N + L D A T T +D LVF + E F + Sbjct 347 HAAV--------NFIPTTRLADFAGAAGSGTVTHTGLVDQFGLVFIKNDDELFLSTT--- 395 Query 1422 GIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNR 1481 G+G ++F L +R +VL + A P R +S+ID + +LD W NR Sbjct 396 GVG-------ELFPDCDARTLADRFERVLSEMTADPRRPLSAIDVRAEAQCPQLDLWSNR 448 Query 1482 AVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGP 1541 LT P P P+SIP++ A QV R P A AV CG S++YR LDEASNRLAH L G GP Sbjct 449 GALTHPVPRPLSIPELFAEQVVRDPGAVAVSCGGRSVSYRGLDEASNRLAHLLISHGVGP 508 Query 1542 GECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRS 1601 G+ VALL R AVVA++ VLKTGAAY+PIDP+ P R+ F+L DA PV VTTA L Sbjct 509 GQRVALLLSRSVEAVVAIMGVLKTGAAYVPIDPSVPDARLRFVLCDAGPVVVVTTAELAD 568 Query 1602 RLAGHDLPIIDVVDALAAYPGTPPP----MPAAVNLAYILYTSGTTGEPKGVGITHRNVT 1657 RLAGH L ++D+ D A Y G P MP ++AY++YTSGTTG PKGV I H NVT Sbjct 569 RLAGHGLTVVDI-DGRAVY-GQPSAALSIMPHPDDVAYLIYTSGTTGTPKGVAIPHHNVT 626 Query 1658 RLFASLPA--RLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGL 1715 RL ++ A L Q W+QCHS FD S WEI+GALL GGRLV+VPE V +P + H L Sbjct 627 RLLEAIDADLELVPGQGWAQCHSLAFDFSVWEIFGALLHGGRLVVVPEGVTRAPEELHAL 686 Query 1716 LVAEHVSVLTQTPAAVAML-------PTQGLESVALVV-AGEACPAALVDRWAPGRV--- 1764 LV E VSVL+QTP+A L P Q ++++VV GEA A + W Sbjct 687 LVHERVSVLSQTPSAFYALHAVDTASPEQRQLALSVVVFGGEALEPARLSDWFQDHPQSP 746 Query 1765 -MLNAYGPTETTICAA---ISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGEL 1820 ++N YG TETT+ A+ I+ G+ PIG P++ + FVLD WLRP+ AG GEL Sbjct 747 RLINMYGITETTVHASFREITVSDVVGTS-SPIGAPLADLSFFVLDDWLRPLQAGAVGEL 805 Query 1821 YIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVK 1880 Y+AGAGVG GY R LTA+RFVACPFGG G RMYRTGDLVCW +DGQL +LGR D+QVK Sbjct 806 YVAGAGVGYGYAGRTSLTATRFVACPFGGRGTRMYRTGDLVCWGSDGQLRYLGRADEQVK 865 Query 1881 IRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLA 1940 IRGYRIELGEV +ALA L GV Q VIAREDRPGDKRLVGY T G+ DP LR L Sbjct 866 IRGYRIELGEVQSALAALEGVDQVAVIAREDRPGDKRLVGYFT----GSADPGELRETLT 921 Query 1941 QRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARV 2000 RLP Y+VPAA+VV+++LPLTVNGKLD ALPAPEY YR PA VE+T+A I+A+V Sbjct 922 DRLPSYMVPAAIVVLESLPLTVNGKLDRNALPAPEYRAVERYRRPATVVEETLAAIYAQV 981 Query 2001 LGLERVGVDDSFFELGGDSLAAMRVIAAI 2029 LGLERVG DDSFFELGGDS+ AM+V +A+ Sbjct 982 LGLERVGADDSFFELGGDSILAMQVSSAV 1010 Score = 104 bits (260), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 197/793 (25%), Positives = 304/793 (39%), Gaps = 98/793 (12%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L+ G PG + + + + ++ G Y D + + + + G ++ Sbjct 501 LISHGVGPGQRVALLLSRSVEAVVAIMGVLKTGAAYVPIDPSVPDARLRFVLCDAGPVVV 560 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLAT-----KTAYIMPTSGTTGQPKL 589 VT ++A + GH +D R A L+ AY++ TSGTTG PK Sbjct 561 VTTAELADR---LAGHGLTVVDIDGRAVYGQPSAALSIMPHPDDVAYLIYTSGTTGTPKG 617 Query 590 VRISHGSLAVFCDAISR------AYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV- 642 V I H ++ +AI GW QC L D SV EIFG G RLV Sbjct 618 VAIPHHNVTRLLEAIDADLELVPGQGWA------QCHSLAFDFSVWEIFGALLHGGRLVV 671 Query 643 --RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGE 700 +L AL+ + R + + P+A + L D + + + L +V GGE Sbjct 672 VPEGVTRAPEELHALL--VHERVSVLSQTPSAFYALHAVDTASPEQ-RQLALSVVVFGGE 728 Query 701 AIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPN 760 A+ + + W + Q L++ YG TE TV A+F I G +G P+ Sbjct 729 ALEPARLSDWFQDH-PQSPRLINMYGITETTVHASFREITVSDVV--GTSSPIGAPLADL 785 Query 761 TVFL-----------AFGEVVIVG-----------DLVADGYLGIDGDGFGTVTAADGSR 798 + F+ A GE+ + G L A ++ G GT Sbjct 786 SFFVLDDWLRPLQAGAVGELYVAGAGVGYGYAGRTSLTATRFVACPFGGRGT-------- 837 Query 799 RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSG 858 R + TGD V ++G + GR D VKI G R+++ EV +A V VAV Sbjct 838 -RMYRTGDLVCWGSDGQLRYLGRADEQVKIRGYRIELGEVQSALAALEGVDQVAVIARED 896 Query 859 SLG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDN 914 G V + + GE R+ +V +V + ++P NGK+D + Sbjct 897 RPGDKRLVGYFTGSADPGELRETLTDRLPSYMVPAA-----IVVLESLPLTVNGKLDRNA 951 Query 915 LPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPET 973 LP P++ A L+ I+++ LG +G D S G S+ +++ Sbjct 952 LPA-PEYRAVERYRRPATVVEETLAAIYAQVLGLERVGADDSFFELGGDSILAMQV-SSA 1009 Query 974 RRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRP-AAIPLSFAQRRL 1032 R G D+ T A LA+ G+ PL P A P+ + Sbjct 1010 VRMAGLACRPRDIFVQQTVARLAEV-----VVAGDTIAEPLDEGTGPVTATPI------M 1058 Query 1033 WFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVI 1092 +L ++ P +N V L+ + A+ A + V+ RH LR L Sbjct 1059 RWLKEIGGPVAEFNQTVVLQAPDGVTGAAVIAMLQAVLDRHAMLRLRAEDHGNGGWLLSA 1118 Query 1093 EARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAV 1151 A A +++ DRL AAR D A L W+ D H LV + Sbjct 1119 AAPGAVEAAQCLESI----DRLTDEALLAARSRLDPAAGAVLSGLWV----DSTHRLVLI 1170 Query 1152 AHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSP 1211 HH+A DG S L DL+ A+ + GR LP + W E+L + S+ P Sbjct 1171 VHHLAVDGVSWRILLEDLNIAWTQQQDGRP---IALPRPGTSFRQWA-ELLSEYTRSE-P 1225 Query 1212 IAAQLAYWENALA 1224 + Q W+ A Sbjct 1226 VVEQAQRWQTVSA 1238 Score = 98.6 bits (244), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 118/444 (27%), Positives = 188/444 (43%), Gaps = 52/444 (11%) Query 1023 IPLSFAQRRLWFLDQLQRPAP--VYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 +PL+ Q L F R VY M + + + G LD + L AV VV RH +L F Sbjct 7699 LPLTPLQHGLLFQANTSRGNSDDVYAMQLDITITGPLDADRLREAVRAVVNRHPNLAARF 7758 Query 1081 PAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQR-----AIEEAARHSFDLATEIPLR 1135 P Q++ A +V+ AD QR A E AA D+ + R Sbjct 7759 DKRFDEPVQIIPANPTAP--WQVVEIDVEQADYEQRLQGLCAAERAA--VCDVVNQSAFR 7814 Query 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 L RI ++EH V HHI DGWS+ L ++ A+Y + P+ Y + Sbjct 7815 AALIRIDENEHRFVMTYHHIVLDGWSLPILLREVFASYYGQR-------LPVASSYRRFV 7867 Query 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPA 1255 W E D+D + L ++ P + RLP R A+ A Sbjct 7868 TWLIE--RDVDGARRAWCEVLKDFDRPALVAP-KGRLPGRR----------ATETFRISA 7914 Query 1256 SVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDP--ALDNLVGF 1313 + V ++AR + T+ V+ A A +L L+G DVA G ++GRS D++VG Sbjct 7915 DISDAVGQLARSQHTTANTVLQAAWAQVLMWLTGRHDVAFGVAVSGRSAEVAGADSMVGL 7974 Query 1314 FVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQV 1373 +NT+ +RV + D + AELL ++ + E+Q + + A+ L Sbjct 7975 LINTVPVRVTVTPDTTIAELLANLQRQHSDTLEHQHLALSEI------QHAVGQEQLFDT 8028 Query 1374 MLAWQDNPVGQLNLGDLQATPMP----IDTRTARMDLVFSLAERFSEGSEPAGIGGAVEY 1429 + +Q+ PV + A+ MP I + R + L + G+E + VE+ Sbjct 8029 LFVYQNYPVQTM------ASSMPDGLSITAVSGREYNHYPLTLQAMPGNE---LVLRVEF 8079 Query 1430 RTDVFEAQAIDVLIERLRKVLVAV 1453 T +F + ++ER ++VL A+ Sbjct 8080 DTGLFGESRVRKVVERFQRVLEAM 8103 Score = 80.5 bits (197), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 177/743 (24%), Positives = 286/743 (39%), Gaps = 94/743 (12%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L+ +GA PG V+ + + + I ++ G Y D A + T + + G + Sbjct 3065 LIDQGAGPGQVVALLSNRSAEAIAAILGILKTGAAYLPIDPAVPDARLTFVLADAGPVVA 3124 Query 535 VTVVDVA----ATQLAVVGHDELRKV--------VDERVTQVTHDALLATKTAYIMPTSG 582 VT D+A LA++ ++R V D + D TAY++ TSG Sbjct 3125 VTTTDLADRLDGRGLAII---DIRGVGPHPPDAGFDGAIPDPEPD-----HTAYLIYTSG 3176 Query 583 TTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVL-QCAPLTSDISVEEIFGGAACGARL 641 TTG PK V +SH ++ D++ H V L D+SV EIFG G R+ Sbjct 3177 TTGVPKGVALSHRNVTQLLDSLDAGL---PHPGVWSHSHSLAFDVSVWEIFGALLSGGRV 3233 Query 642 VRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEA 701 V ++ T L L+ T++ + + L +G +D+ +V+ GEA Sbjct 3234 VIASEGATSSPEDLHALLIREHVTVITQTPSAARALPREG--LDSAA------LVVVGEA 3285 Query 702 IRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQ-----TTMDGALLRLGR 755 VD+W + G ++++YGPTE T+ VA P+ Q T + GA L + Sbjct 3286 CPAEVVDQW-----APGRVMINAYGPTETTMCVAISAPLTAGQGVPIGTPVTGAALFVLD 3340 Query 756 PILPNTVFLAFGEVVIV-----------GDLVADGYLGIDGDGFGTVTAADGSRRRAFAT 804 L GE+ + L + ++ GT R + T Sbjct 3341 ESLRQVPVGVVGELYVAGRGVGYGYVGRAPLTSTRFVACPFGDPGT---------RMYRT 3391 Query 805 GDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG--- 861 GD V +G + GR D VKI G R+++AE+ +A V + V G Sbjct 3392 GDLVCWRPDGQLNYLGRADEQVKIRGHRIELAEIQAVLASLGGVEEAVVIAREDRPGDKR 3451 Query 862 -VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQ 920 V + + G A A R+ +V V V + IP NGK+D+ LP P Sbjct 3452 LVGYITGTADCGGLRMAIADRLPAYMVPAAV-----VRLDAIPLTVNGKLDTRALPA-PD 3505 Query 921 WSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW 979 + G A L+ I+++ LG + D S G S+ ++++ R G Sbjct 3506 YGDHGRYRAPANAVEEVLADIYAQVLGLERVSVDDSFFDLGGDSILSMQVVSRGRAA-GL 3564 Query 980 RLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQ 1039 D+ T A LA G + +PL LW L + Sbjct 3565 LCRPRDIFVEQTVARLARVVQVTAGSRGP------IDEGLGHVVPLPIM---LW-LKGID 3614 Query 1040 RPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQLVIEARRADL 1099 P +N +V ++ + + + + ++ RH LR DGV + + Sbjct 3615 GPIEEFNQSVLVQAPEGVAEDDVVTLLQSLLDRHAMLRLRVSG-DGVGGWSLTVPEPGSV 3673 Query 1100 GCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRT-WLFRIADDEHVLVAVAHHIAAD 1158 TA + L + AR D A + L W+ + LV + HH+A D Sbjct 3674 DAATCLHTA---EYLSDSAVVTARSRLDPAAGVMLSALWVTSTSQ----LVMIVHHLAVD 3726 Query 1159 GWSVAPLTADLSAAYASRCAGRA 1181 G S L D++ +A G++ Sbjct 3727 GVSWRILLEDINLGWAQHRDGQS 3749 >gi|169631176|ref|YP_001704825.1| peptide synthetase NRP [Mycobacterium abscessus ATCC 19977] gi|146760171|emb|CAJ77716.1| Mps2 protein [Mycobacterium abscessus] gi|169243143|emb|CAM64171.1| Probable peptide synthetase NRP [Mycobacterium abscessus] Length=2581 Score = 1358 bits (3516), Expect = 0.0, Method: Compositional matrix adjust. Identities = 806/1532 (53%), Positives = 974/1532 (64%), Gaps = 93/1532 (6%) Query 1023 IPLSFAQRRLWFLDQLQRPA----------PVYNMAVALRLRGYLDTEALGAAVADVVGR 1072 +PL+ Q L F R A Y + + + + G +D L AV VV R Sbjct 1101 LPLTPIQEGLLFHTTFARAAGALEGDEAGIDFYAVQLDITVTGLVDQLRLRDAVHTVVRR 1160 Query 1073 HESLRTVFPAVDGVPRQL-----VIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFD 1127 H +L F G P Q+ VI R DL D D T P + +Q D Sbjct 1161 HPNLAARFCTQFGDPVQVILADPVIAWRYLDLRGD--DLT--PDEEIQHLCAAERAAVCD 1216 Query 1128 LATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPL 1187 LA LR L R ++H V HH+ DGWS+ L ++ A+Y P Sbjct 1217 LADRPTLRAALIRTEGNQHRFVLTFHHVVIDGWSLPILLQEIFASYFGHRL-------PA 1269 Query 1188 PVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPT--ARPYPPVADQR 1245 P Y + W +D + A W L G PT A P PP Sbjct 1270 PSSYRSFVSWL---------ADQDLDAARTAWGKVLEG----FDTPTLVAPPAPP----- 1311 Query 1246 GASLVVDWPASVQ--QQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRS 1303 GA V + S + Q + +AR + T V+ A A LL L+G DVA G ++GR Sbjct 1312 GARGVESYRVSAETTQALGDLARSQHTTVSTVLQAAWAQLLMVLTGQDDVAFGTAVSGR- 1370 Query 1304 DPA----LDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRL 1359 PA D++VG +NT+ +R + AELLGQ+++ E++ + + Sbjct 1371 -PAELAGSDSIVGLLINTVPVRARATASTTIAELLGQLQSAHNDTIEHEHLALNEI---- 1425 Query 1360 KPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSE 1419 H L + ++ P+ +Q + I R + L+ G E Sbjct 1426 --HHVAGHEQLFDTLFLYESYPIDTSAFMGVQE--LAITEFVTREYNHYPLSVMALPGHE 1481 Query 1420 PAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWG 1479 +G VEY TD F I + ER +VLV++ + ++ +SS+D L E +LD WG Sbjct 1482 ---LGIRVEYDTDKFGLDDIQAVFERFERVLVSMVSDADQRLSSLDVLQTDEHKQLDGWG 1538 Query 1480 NRAVLTAPAPTPV-SIPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCG 1538 NR VL P PV SIP+ A QV R PEA A+ S TY ELDEA+NRLA+ L+ G Sbjct 1539 NRKVLVR-GPEPVLSIPEAFAEQVDRAPEAVALTFEGRSTTYGELDEAANRLANLLSVYG 1597 Query 1539 AGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAG 1598 A PGE VALL R A++A++A+LKTGA+YLPIDP+ P R+ FML DAVP+AAVTTA Sbjct 1598 AAPGESVALLMPRSDEAIIAILAILKTGASYLPIDPSVPDTRLEFMLSDAVPIAAVTTAE 1657 Query 1599 LRSRLAGHDLPIIDVVDAL-----AAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITH 1653 LR+R G + ++ DA A Y TP PA ++AY +YTSGTTG PKGV I H Sbjct 1658 LRARFDGSGVSVVQFDDAEDDPTGAIYGHTPLLTPAPDDIAYTIYTSGTTGVPKGVAIAH 1717 Query 1654 RNVTRL--FASLPARLSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPND 1711 NVT+ F +VW+Q S FD + WEI+GALL GGRLVI+P+SV SP+D Sbjct 1718 SNVTQALKFPLTHMPTGPGEVWTQAGSLVFDITVWEIFGALLHGGRLVIIPDSVVRSPDD 1777 Query 1712 FHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGP 1771 F LL+ E V+VL QTP+AV ML +GL ++ LVVAGEACP +VDRWAPGRVM+N YGP Sbjct 1778 FRDLLIREKVTVLFQTPSAVGMLSPEGLNNLTLVVAGEACPTEVVDRWAPGRVMINGYGP 1837 Query 1772 TETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGY 1831 TETTI A L GSG+ PIGVPV AALFVLD W+RPVP GV GELY+AG GVG+GY Sbjct 1838 TETTIYATFGE-LIAGSGVVPIGVPVPDAALFVLDRWMRPVPPGVVGELYVAGLGVGIGY 1896 Query 1832 WRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD----GQLEFLGRTDDQVKIRGYRIE 1887 +R LTA+RFVACPFG G RMYRTGDLV W GQLE+LGR D+QVKIRG+RIE Sbjct 1897 VKRQALTAARFVACPFGEPGTRMYRTGDLVRWGVSESSVGQLEYLGRADEQVKIRGFRIE 1956 Query 1888 LGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYL 1947 LGE+ ALA++ GV QA VIAREDRPGDKRLVGY G +PA LRA LA+RLP Y+ Sbjct 1957 LGEIQAALADVDGVEQAAVIAREDRPGDKRLVGYFI----GTGEPAELRAALAKRLPPYM 2012 Query 1948 VPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVG 2007 VPAA+V ++ALPLTVNGKLD RALPAPEY D YRAPA VE+ VAGI+A+VLG+ERVG Sbjct 2013 VPAALVRLEALPLTVNGKLDKRALPAPEYDDAARYRAPANAVEEAVAGIYAQVLGVERVG 2072 Query 2008 VDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLL-GRDARPTSDPR 2066 DDSFF+LGGDS++AMRV+AAINT+ +A L VR L A S R LS L G P + P Sbjct 2073 TDDSFFDLGGDSISAMRVVAAINTSFDAQLAVRTLFEAPSVRSLSGYLDGAAGAPANGPT 2132 Query 2067 LVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLE 2126 SVHG TEV ASDLTLD+FID TL A LP RTVLLTGATGFLGRYLVL+ Sbjct 2133 YASVHGPGATEVRASDLTLDKFIDEATLQKAPTLPRAEATARTVLLTGATGFLGRYLVLQ 2192 Query 2127 LLRRLD-VDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSE 2185 LR L+ VDG LICLVRA+SDE+ARRRL+KTFDSGDPEL+R ++ LAADRL+V+AGDK+E Sbjct 2193 WLRELEQVDGTLICLVRAKSDEEARRRLDKTFDSGDPELIRVYEALAADRLQVIAGDKAE 2252 Query 2186 PDLGLDQPMWRRLAETVDLIVDSAAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFT 2244 P LGLDQ W+RLA+TVDLIVDSAA+VN+ PY ELFGPNV GTAELIR ALTTKLKP+T Sbjct 2253 PSLGLDQDTWQRLADTVDLIVDSAALVNSVLPYSELFGPNVVGTAELIRFALTTKLKPYT 2312 Query 2245 YVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALP 2304 Y+STADVG IE S F EDADIRVIS TR DG +A GYG SKWAGEVLLREA++ LP Sbjct 2313 YISTADVGREIEKSVFREDADIRVISATRPSDGSYANGYGNSKWAGEVLLREAHEQVGLP 2372 Query 2305 VAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLP 2364 V VFR GMI+ DTSYAGQ+N SD V RMVLS++ATG+AP S Y+ D++GNRQRAHFDGLP Sbjct 2373 VKVFRSGMIMVDTSYAGQVNASDTVARMVLSVVATGVAPYSVYQLDADGNRQRAHFDGLP 2432 Query 2365 VTFVAEAIAVLGARVAGS--SLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDF 2422 V FVAEAI LG AGS A F TYHVMNPHDDGIG+DEYVDWLIEAG+PI RIDDF Sbjct 2433 VEFVAEAITALGGGAAGSFDGSADFETYHVMNPHDDGIGIDEYVDWLIEAGHPIERIDDF 2492 Query 2423 AEWLQRFEASLGALPDRQRRHSVLPML--LASNSQRLQPLKPTRGCSAPTDRFRAAVRAA 2480 EW+++FEA L ALPD QR+ SVL ML L + QP +P RG AP DRF AAVR A Sbjct 2493 GEWVRQFEARLHALPDHQRQGSVLQMLKILQDHGWDGQPPEPVRGPMAPADRFHAAVRKA 2552 Query 2481 KVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL 2512 K+GSD DIP VSAP I Y ++LQL GLL Sbjct 2553 KIGSDH---DIPQVSAPIIAKYASDLQLHGLL 2581 Score = 698 bits (1801), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/582 (64%), Positives = 437/582 (76%), Gaps = 13/582 (2%) Query 1453 VAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVC 1512 ++A P RT+ S+D LD + RLDEWGNRAVLT PA PVSIP + A QV R PE A+ Sbjct 1 MSADPTRTLLSMDLLDDDDHDRLDEWGNRAVLTEPAAEPVSIPVVFAVQVERAPETVALV 60 Query 1513 CGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPI 1572 C D S TYRELD+ +NR+AH LAG GAGPGE V LL R A++ ++A+LKTGAAYLPI Sbjct 61 CRDRSWTYRELDQITNRIAHLLAGNGAGPGEVVGLLVPRSGEAIIGLLAILKTGAAYLPI 120 Query 1573 DPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALA-AYPGTPPPMPAAV 1631 DPA+P R+ FM+ DA PVA +TTA L SR G D+ +I++ D L P + P P Sbjct 121 DPAHPDERIKFMVSDAGPVAVLTTADLGSRFEGLDVSVIEIDDPLIDGQPSSALPTPEPD 180 Query 1632 NLAYILYTSGTTGEPKGVGITHRNVTRLF----ASLPARLSAAQVWSQCHSYGFDASAWE 1687 +LAY+ YTSGTTG PK V +TH NVT+L A LPAR +VWSQ HS FD S WE Sbjct 181 DLAYMTYTSGTTGVPKAVAVTHHNVTQLVDAVRADLPAR--PGEVWSQWHSLVFDVSVWE 238 Query 1688 IWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVA 1747 IWGALL GGRLV+VPESVA+SP+D H LL++E VSVL QTP+A ML + LES L+VA Sbjct 239 IWGALLHGGRLVVVPESVASSPDDLHELLISEKVSVLCQTPSAAGMLSPERLESTTLIVA 298 Query 1748 GEACPAALVDRWA-PGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLD 1806 GEACP LVDRWA GR M+NAYGPTE TI AA+S PL PGSG+ PIG PV GAALFVLD Sbjct 299 GEACPPELVDRWATSGRTMINAYGPTEATIYAAMSGPLTPGSGVAPIGSPVPGAALFVLD 358 Query 1807 SWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD 1866 WLRP P GV GELY+AG GV GY R+GLTASRF+ACPFGG G+RMYRTGDLV W D Sbjct 359 KWLRPAPEGVVGELYVAGNGVAPGYAHRSGLTASRFLACPFGGPGSRMYRTGDLVQWGED 418 Query 1867 GQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIA 1926 GQL++LGR D+QVKIRGYRIELGE+ AL+ L GV QAVVIAREDRPGDKRLVGY Sbjct 419 GQLQYLGRADEQVKIRGYRIELGEIQAALSRLDGVEQAVVIAREDRPGDKRLVGYIM--- 475 Query 1927 PGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDT-NGYRAP 1985 G DP R LA+RLP Y+VPAAVVV+DALPLTVNGKLD RALPAPEY YRAP Sbjct 476 -GTADPVEARNALAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRSVGTDYRAP 534 Query 1986 AGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +GPVEK +A I+A+VLG++RVGVD+SFF+LGGDS+ +M+V++ Sbjct 535 SGPVEKVLADIYAQVLGVDRVGVDESFFDLGGDSILSMQVVS 576 Score = 103 bits (257), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 184/744 (25%), Positives = 296/744 (40%), Gaps = 95/744 (12%) Query 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 L GA PG+V+ + + I L+A G Y D A +++ G + Sbjct 82 LAGNGAGPGEVVGLLVPRSGEAIIGLLAILKTGAAYLPIDPAHPDERIKFMVSDAGPVAV 141 Query 535 VTVVDVAATQLAVVGHDELRKVVDERVTQVTHDALLAT----KTAYIMPTSGTTGQPKLV 590 +T D+ + G D +D+ + + L T AY+ TSGTTG PK V Sbjct 142 LTTADLGSR---FEGLDVSVIEIDDPLIDGQPSSALPTPEPDDLAYMTYTSGTTGVPKAV 198 Query 591 RISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAM 647 ++H ++ DA+ + Q L D+SV EI+G G RLV S A Sbjct 199 AVTHHNVTQLVDAVRADLPARPGEVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVAS 258 Query 648 KTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQ--IVIGGEAIRCS 705 DL L L++ + ++ LC A + RL +++ GEA Sbjct 259 SPDDLHEL---LISEKVSV----------LCQTPSAAGMLSPERLESTTLIVAGEACPPE 305 Query 706 AVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL- 764 VD+W A+ G +++++YGPTEAT+ A + T + +G P+ +F+ Sbjct 306 LVDRW----ATSGRTMINAYGPTEATIYAA----MSGPLTPGSGVAPIGSPVPGAALFVL 357 Query 765 ----------AFGEVVIVGDLVADGYLGIDGDGFGTVTAA--DGSRRRAFATGDRVTVDA 812 GE+ + G+ VA GY G A G R + TGD V Sbjct 358 DKWLRPAPEGVVGELYVAGNGVAPGYAHRSGLTASRFLACPFGGPGSRMYRTGDLVQWGE 417 Query 813 EGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQR 868 +G + GR D VKI G R+++ E+ ++ V V G V + Sbjct 418 DGQLQYLGRADEQVKIRGYRIELGEIQAALSRLDGVEQAVVIAREDRPGDKRLVGYIMGT 477 Query 869 TREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNT 928 E A A R+ +V VV + +P NGK+D LP P++ + G + Sbjct 478 ADPVEARNALAERLPAYMVPAA-----VVVLDALPLTVNGKLDKRALPA-PEYRSVGTDY 531 Query 929 -AETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDL 986 A +G L+ I+++ LG +G D S G S+ ++++ R G D+ Sbjct 532 RAPSGPVEKVLADIYAQVLGVDRVGVDESFFDLGGDSILSMQVVSRARA-AGVHCRPRDI 590 Query 987 IGADTAANLADYAPTPDAPTG--EDRFRPLVAAQRPAAIPLSFAQRRLWFLDQLQRPAPV 1044 T + +A A D G +D P++A P+ + +L + P Sbjct 591 FVEQTVSGVAAVASLSDGRAGIVDDGIGPVLAT------PI------IHWLQGVPGPVDQ 638 Query 1045 YNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDG-------VPRQLVIEARRA 1097 +N + L+ + + + + ++ RH +LR + D VP ++AR Sbjct 639 FNQTIVLQAPVGVTEDDVVVILQALLDRHATLRLRAESGDASGGWSLLVPDTGTVDAR-- 696 Query 1098 DLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR-TWLFRIADDEHVLVAVAHHIA 1156 C V A+ L A AAR + A L W+ D L + HH+A Sbjct 697 --ACLRV------AESLSDAELVAARSRLNPAAGAQLSAVWV----PDSRQLALMIHHLA 744 Query 1157 ADGWSVAPLTADLSAAYASRCAGR 1180 DG S L DL+ A+A G+ Sbjct 745 VDGVSWRILLEDLNIAWAQHHGGQ 768 Score = 96.3 bits (238), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 152/564 (27%), Positives = 224/564 (40%), Gaps = 85/564 (15%) Query 479 GAAPGDVLVFTDDDTDKTIDLLIACHLAGCGY-----SVCDTADEI---------SVRTN 524 GAAPG+ + +D+ I ++A G Y SV DT E +V T Sbjct 1597 GAAPGESVALLMPRSDEAIIAILAILKTGASYLPIDPSVPDTRLEFMLSDAVPIAAVTTA 1656 Query 525 AITEHGDGILVTVVDVAATQL----AVVGHDELRKVVDERVTQVTHDALLATKTAYIMPT 580 + DG V+VV + A+ GH L +T D AY + T Sbjct 1657 ELRARFDGSGVSVVQFDDAEDDPTGAIYGHTPL-------LTPAPDD------IAYTIYT 1703 Query 581 SGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGAR 640 SGTTG PK V I+H ++ G + Q L DI+V EIFG G R Sbjct 1704 SGTTGVPKGVAIAHSNVTQALKFPLTHMPTGPGEVWTQAGSLVFDITVWEIFGALLHGGR 1763 Query 641 LV---RSAAMKTGDLAALVDDLVARE--TTIVDLPTAVWQLLCADGDAIDAIGRSRLRQI 695 LV S D DL+ RE T + P+AV L G + L + Sbjct 1764 LVIIPDSVVRSPDDFR----DLLIREKVTVLFQTPSAVGML--------SPEGLNNL-TL 1810 Query 696 VIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTM-------DG 748 V+ GEA VD+W + G +++ YGPTE T+ ATF ++ + D Sbjct 1811 VVAGEACPTEVVDRW-----APGRVMINGYGPTETTIYATFGELIAGSGVVPIGVPVPDA 1865 Query 749 ALL---RLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSR--RRAFA 803 AL R RP+ P V GE+ + G V GY+ A R + Sbjct 1866 ALFVLDRWMRPVPPGVV----GELYVAGLGVGIGYVKRQALTAARFVACPFGEPGTRMYR 1921 Query 804 TGDR----VTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGS 859 TGD V+ + G + GR D VKI G R+++ E+ +A+ V AV Sbjct 1922 TGDLVRWGVSESSVGQLEYLGRADEQVKIRGFRIELGEIQAALADVDGVEQAAVIAREDR 1981 Query 860 LG----VWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNL 915 G V + E AA A R+ +V +V + +P NGK+D L Sbjct 1982 PGDKRLVGYFIGTGEPAELRAALAKRLPPYMVPAA-----LVRLEALPLTVNGKLDKRAL 2036 Query 916 PRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETR 974 P P++ A A ++ I+++ LG +G D S G S+ +R++ Sbjct 2037 PA-PEYDDAARYRAPANAVEEAVAGIYAQVLGVERVGTDDSFFDLGGDSISAMRVVAAIN 2095 Query 975 RYLGWRLSLLDLIGADTAANLADY 998 +L++ L A + +L+ Y Sbjct 2096 TSFDAQLAVRTLFEAPSVRSLSGY 2119 >gi|254775688|ref|ZP_05217204.1| syringomycin synthetase [Mycobacterium avium subsp. avium ATCC 25291] Length=3252 Score = 1358 bits (3514), Expect = 0.0, Method: Compositional matrix adjust. Identities = 791/1481 (54%), Positives = 959/1481 (65%), Gaps = 63/1481 (4%) Query 571 ATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEE 630 A A+++ TSGTTG+PK V +SH ++ ++ G QC L D SV E Sbjct 1606 AGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTGITLGPDQVWSQCHSLAFDFSVWE 1665 Query 631 IFGGAACGARLV---RSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAI 687 I+ G RLV + A DL L+ + R T + P+A L D++ Sbjct 1666 IWAALLHGGRLVVVSDAVARSPDDLRRLL--IRERVTVLTQTPSAAGALSPQGLDSV--- 1720 Query 688 GRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATV-VATFLPIVCDQTTM 746 +VIG E VD+W +++ YGPTE T+ V+ P+ Sbjct 1721 ------ALVIGAEPCPPELVDRWAPDRV-----MINVYGPTETTMWVSHSRPLAAGSGAP 1769 Query 747 DGALLRLGRPILPNTVF-----LAFGEVVIVGDLVADGYLGIDGDGFGTVTAAD------ 795 +G P+ + F L V + G+L G G A Sbjct 1770 P-----IGSPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVACP 1824 Query 796 --GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAV 853 G+ R + TGD V A+G + GR D VKI G R+++ E+ + + V AV Sbjct 1825 FGGTGTRMYRTGDLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSALTDLDGVEQAAV 1884 Query 854 ELHSGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFF---VVGVPNIPRKPNGKI 910 S G +R A ++R L V+ + +P NGK+ Sbjct 1885 IAREDSPG----HKRLVAYLTGTADPAQVRTQLADRLPGYMLPSAVLALDALPLTVNGKL 1940 Query 911 DSDNLPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRI 969 D+ LP P+ A A L+ +++R LG +G D S G SL +R+ Sbjct 1941 DTRALPA-PELRAENRYRAPQNPTEESLADVYARLLGLERVGVDDSFFELGGDSLSAMRL 1999 Query 970 LPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQ 1029 + L L++ L A T A LA P G R LVAA+RPA +PLSFAQ Sbjct 2000 ITAVNAELDADLTVRALFEAPTVAQLA-----PRVAAGTGRAGRLVAAERPAVLPLSFAQ 2054 Query 1030 RRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPRQ 1089 RLWF+DQL P+PVYNMAVAL LRG LDT+ALGAA+ DVV RHESLRT+FPA DG PRQ Sbjct 2055 SRLWFIDQLHGPSPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRTLFPAPDGAPRQ 2114 Query 1090 LVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEHVLV 1149 +V+EA RA++ +VDA WPA L A EAAR++FDLATEIPLR WLFR DEHVLV Sbjct 2115 VVLEAERAEVDWQVVDAARWPASWLAEATHEAARYTFDLATEIPLRAWLFRRNHDEHVLV 2174 Query 1150 AVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSD 1209 AV HHIAADGWS+ PL DL AAYASRC GR PDWAPLPVQY DYTLWQR GDLDD D Sbjct 2175 AVVHHIAADGWSLTPLVRDLGAAYASRCRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPD 2234 Query 1210 SPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHN 1269 SPIA QL YW+ ALAGMPER+ LPT RPYP VAD GAS+ V WPA +QQ + ++AR HN Sbjct 2235 SPIATQLQYWQRALAGMPERVALPTDRPYPLVADHLGASVQVHWPAELQQHIAQLARTHN 2294 Query 1270 ATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPS 1329 ATSFMVV A LAVLLS LS +PDVAVGFPIAGR DPALD++VGFFVNTLVLRV+LA DPS Sbjct 2295 ATSFMVVQAALAVLLSTLSANPDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDLADDPS 2354 Query 1330 FAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGD 1389 AELLGQVR RSL AYENQDVPFE+LV+RL PTR+L HHPL+QVMLAWQ+N ++LGD Sbjct 2355 IAELLGQVRHRSLQAYENQDVPFELLVERLNPTRSLAHHPLVQVMLAWQNNDPVDVSLGD 2414 Query 1390 LQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKV 1449 + TPMP++ + ARMDLV+SLAER++ P GI G VE+RTDVF+A +I+ L+ RL++V Sbjct 2415 VHVTPMPLENQVARMDLVWSLAERWTADGRPDGIDGTVEFRTDVFDAASIETLVRRLQRV 2474 Query 1450 LVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAE 1509 L+A+ A P R VSSID LD E A LD GNRA LT PA VSI Q+ AAQVAR PEA Sbjct 2475 LLAMTADPARPVSSIDILDEPEYAHLDALGNRAALTRPATGWVSISQLFAAQVARTPEAV 2534 Query 1510 AVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAY 1569 A+ CG+ S TYRELD ++NRLA LAG GA PGE VA+L R A AVV+++AVLKTGAAY Sbjct 2535 AISCGERSWTYRELDSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSILAVLKTGAAY 2594 Query 1570 LPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYP---GTPPP 1626 +PIDP P R+ FML DAVPV VTTA LR+ AG ++ + D P G P Sbjct 2595 VPIDPGLPSARIDFMLADAVPVVTVTTAELRAS-AGDPDRVVAIDDPAPHVPRIGGRAAP 2653 Query 1627 MPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWSQCHSYGFDASAW 1686 P ++AY++YTSGTTG PKGV +TH NVT+L SL RL +VWSQCHS FD S W Sbjct 2654 APD--DIAYVIYTSGTTGVPKGVAVTHHNVTQLLGSLDDRLGLGRVWSQCHSLAFDFSVW 2711 Query 1687 EIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVV 1746 EI+GALL GGRLVIVP+ V SP D H LL+ E V+VL+QTP+A A L + LESVALV+ Sbjct 2712 EIFGALLRGGRLVIVPDDVVRSPEDLHALLIGEGVTVLSQTPSAAAALSPERLESVALVL 2771 Query 1747 AGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLD 1806 GEACP L+DRWAPGR+M+N YGPTETT+ A ++ PLR G PIG PV GAALFVLD Sbjct 2772 GGEACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLRAGGAAVPIGSPVPGAALFVLD 2831 Query 1807 SWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRAD 1866 LR VP GV GELY+AG GV GY RA LTASRFVACPFGG+G RMYRTGDL W AD Sbjct 2832 GRLRRVPPGVVGELYVAGRGVAAGYLGRAALTASRFVACPFGGTGTRMYRTGDLARWGAD 2891 Query 1867 GQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIA 1926 GQL ++GR D+QVKIRG+RIELGE+ + LA L GV QA VIAR+D G RLV Y T Sbjct 2892 GQLHYVGRADEQVKIRGFRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYIT--- 2948 Query 1927 PGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEYGDTNGYRAPA 1986 G DPA LRAQLA RLPGY+VP+AVVV+DALPLT NGKLD RALPAP+Y YRAP Sbjct 2949 -GTADPAELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTRALPAPDYAGGR-YRAPG 3006 Query 1987 GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 +E+ +AGI+A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct 3007 DAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 3047 Lambda K H 0.320 0.136 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 6661886318010 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40