BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0106 Length=398 Score E Sequences producing significant alignments: (Bits) Value gi|15607248|ref|NP_214620.1| hypothetical protein Rv0106 [Mycoba... 794 0.0 gi|254233500|ref|ZP_04926826.1| conserved hypothetical protein [... 791 0.0 gi|340625142|ref|YP_004743594.1| hypothetical protein MCAN_01091... 786 0.0 gi|183980324|ref|YP_001848615.1| hypothetical protein MMAR_0293 ... 566 3e-159 gi|118619875|ref|YP_908207.1| hypothetical protein MUL_4830 [Myc... 563 2e-158 gi|342859238|ref|ZP_08715892.1| CobW/P47K domain-containing prot... 519 4e-145 gi|169627439|ref|YP_001701088.1| cobalamin synthesis protein [My... 515 4e-144 gi|254777315|ref|ZP_05218831.1| CobW/P47K domain-containing prot... 505 6e-141 gi|254818908|ref|ZP_05223909.1| CobW/P47K domain-containing prot... 494 1e-137 gi|118464058|ref|YP_883996.1| CobW/P47K domain-containing protei... 486 2e-135 gi|41409868|ref|NP_962704.1| hypothetical protein MAP3770 [Mycob... 486 2e-135 gi|336460198|gb|EGO39102.1| putative GTPase, G3E family [Mycobac... 485 6e-135 gi|108801695|ref|YP_641892.1| cobalamin synthesis CobW-like prot... 463 3e-128 gi|126437681|ref|YP_001073372.1| cobalamin synthesis CobW domain... 462 5e-128 gi|120406434|ref|YP_956263.1| cobalamin synthesis CobW domain-co... 434 1e-119 gi|118471890|ref|YP_890291.1| CobW/P47K domain-containing protei... 416 4e-114 gi|120406280|ref|YP_956109.1| cobalamin synthesis CobW domain-co... 399 4e-109 gi|145221905|ref|YP_001132583.1| cobalamin synthesis CobW domain... 383 3e-104 gi|41409845|ref|NP_962681.1| hypothetical protein MAP3747c [Myco... 381 1e-103 gi|336460146|gb|EGO39051.1| putative GTPase, G3E family [Mycobac... 380 2e-103 gi|226365091|ref|YP_002782874.1| hypothetical protein ROP_56820 ... 359 4e-97 gi|111022584|ref|YP_705556.1| hypothetical protein RHA1_ro05618 ... 357 2e-96 gi|229495110|ref|ZP_04388856.1| CobW/P47K domain protein [Rhodoc... 352 6e-95 gi|312138608|ref|YP_004005944.1| hypothetical protein REQ_11600 ... 345 1e-92 gi|325676325|ref|ZP_08156004.1| cobalamin synthesis CobW family ... 342 5e-92 gi|226307889|ref|YP_002767849.1| hypothetical protein RER_44020 ... 338 1e-90 gi|333921229|ref|YP_004494810.1| hypothetical protein AS9A_3572 ... 334 1e-89 gi|343928747|ref|ZP_08768192.1| hypothetical protein GOALK_120_0... 277 2e-72 gi|54026948|ref|YP_121190.1| hypothetical protein nfa49740 [Noca... 276 3e-72 gi|134097361|ref|YP_001103022.1| cobalamin synthesis CobW-like p... 271 2e-70 gi|291009080|ref|ZP_06567053.1| cobalamin synthesis CobW-like pr... 270 2e-70 gi|296140971|ref|YP_003648214.1| cobalamin synthesis CobW domain... 270 4e-70 gi|262201432|ref|YP_003272640.1| cobalamin synthesis CobW domain... 251 1e-64 gi|325003292|ref|ZP_08124404.1| cobalamin synthesis CobW-like pr... 248 1e-63 gi|331696033|ref|YP_004332272.1| cobalamin synthesis CobW domain... 244 1e-62 gi|302527618|ref|ZP_07279960.1| predicted protein [Streptomyces ... 232 9e-59 gi|326383109|ref|ZP_08204798.1| cobalamin synthesis CobW domain-... 195 1e-47 gi|256378449|ref|YP_003102109.1| cobalamin synthesis CobW domain... 187 2e-45 gi|238063059|ref|ZP_04607768.1| cobalamin synthesis protein cobW... 153 5e-35 gi|157145192|ref|YP_001452511.1| hypothetical protein CKO_00925 ... 144 3e-32 gi|284919703|emb|CAX65480.1| hypothetical protein [Enterobacter ... 144 3e-32 gi|38639671|ref|NP_943440.1| CobW [Klebsiella pneumoniae] >gi|16... 139 1e-30 gi|339764734|gb|AEK00954.1| CobW [Klebsiella pneumoniae KCTC 2242] 138 2e-30 gi|257095797|ref|YP_003169438.1| cobalamin synthesis protein P47... 136 5e-30 gi|313200673|ref|YP_004039331.1| cobalamin synthesis protein p47... 136 7e-30 gi|291300850|ref|YP_003512128.1| cobalamin synthesis CobW domain... 135 2e-29 gi|302868522|ref|YP_003837159.1| cobalamin synthesis CobW domain... 134 2e-29 gi|317053880|ref|YP_004117905.1| cobalamin synthesis protein P47... 134 3e-29 gi|323519849|gb|ADX94230.1| CobW/P47K family protein [Acinetobac... 134 4e-29 gi|342225721|gb|EGT90707.1| CobW/HypB/UreG, nucleotide-binding d... 133 5e-29 >gi|15607248|ref|NP_214620.1| hypothetical protein Rv0106 [Mycobacterium tuberculosis H37Rv] gi|15839486|ref|NP_334523.1| hypothetical protein MT0115 [Mycobacterium tuberculosis CDC1551] gi|31791284|ref|NP_853777.1| hypothetical protein Mb0109 [Mycobacterium bovis AF2122/97] 78 more sequence titles Length=398 Score = 794 bits (2050), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/398 (100%), Positives = 398/398 (100%), Gaps = 0/398 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF Sbjct 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG Sbjct 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV Sbjct 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF Sbjct 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM Sbjct 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP Sbjct 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR 398 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR Sbjct 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR 398 >gi|254233500|ref|ZP_04926826.1| conserved hypothetical protein [Mycobacterium tuberculosis C] gi|124603293|gb|EAY61568.1| conserved hypothetical protein [Mycobacterium tuberculosis C] Length=398 Score = 791 bits (2044), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/398 (99%), Positives = 397/398 (99%), Gaps = 0/398 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF Sbjct 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG Sbjct 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV Sbjct 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF Sbjct 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM Sbjct 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP Sbjct 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR 398 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSA RNSGESR Sbjct 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSARRNSGESR 398 >gi|340625142|ref|YP_004743594.1| hypothetical protein MCAN_01091 [Mycobacterium canettii CIPT 140010059] gi|340003332|emb|CCC42450.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059] Length=398 Score = 786 bits (2031), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/398 (99%), Positives = 396/398 (99%), Gaps = 0/398 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFD HVVRRMTATLSRGELITTEDALE Sbjct 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDCHVVRRMTATLSRGELITTEDALEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG Sbjct 61 AHGCVSCTIRNDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV Sbjct 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF Sbjct 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM Sbjct 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP Sbjct 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR 398 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR Sbjct 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR 398 >gi|183980324|ref|YP_001848615.1| hypothetical protein MMAR_0293 [Mycobacterium marinum M] gi|183173650|gb|ACC38760.1| conserved protein [Mycobacterium marinum M] Length=398 Score = 566 bits (1458), Expect = 3e-159, Method: Compositional matrix adjust. Identities = 298/396 (76%), Positives = 327/396 (83%), Gaps = 0/396 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPV+LVAGQ TD+VTG LLRR GTVVVEHRFDGHVVRR T RGEL T E+ LE Sbjct 1 MRTPVVLVAGQGDTDDVTGLLLRRPGTVVVEHRFDGHVVRRNIITFRRGELSTAEEVLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLL+LLRRLHRRD V RIVVHLAPWLEP+PICWAI+HVRV VG GYPD Sbjct 61 AHGCVSCTIRNDLLILLRRLHRRDGVDRIVVHLAPWLEPEPICWAINHVRVRVGPGYPDA 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PA DVR+ AVVTCVD WL QSLG++EL DGRT AQVTVGQAEFAD+LVL P+PV + Sbjct 121 PAGRDVRIGAVVTCVDSANWLAQSLGDEELADGRTFAQVTVGQAEFADVLVLNRPDPVTL 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVL RLAPRARIT G+DRVELALA+LDD SRRGR+D PH LL G PPL DG V IVEF Sbjct 181 AVLPRLAPRARITVGLDRVELALANLDDYSRRGRSDHPHASLLGGRPPLGTDGGVGIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPF P+RLH AVD LLDGV+RTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM Sbjct 241 NARRPFRPERLHDAVDHLLDGVIRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + +EV + D ERRLFA+LMW Y FGDRHTAMTVL CGAD +I L ALL+D EMA P Sbjct 301 SPAEVDHADPERRLFAELMWEYRFGDRHTAMTVLACGADRAEITRVLTGALLTDREMARP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 Q W +Y DPFGDWH+DPCHE PD +G+FS H N GE Sbjct 361 QDWPAYDDPFGDWHEDPCHETPDESGQFSGHLNKGE 396 >gi|118619875|ref|YP_908207.1| hypothetical protein MUL_4830 [Mycobacterium ulcerans Agy99] gi|118571985|gb|ABL06736.1| conserved protein [Mycobacterium ulcerans Agy99] Length=398 Score = 563 bits (1451), Expect = 2e-158, Method: Compositional matrix adjust. Identities = 297/396 (75%), Positives = 327/396 (83%), Gaps = 0/396 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPV+LVAGQ TD+VTG LLRR GTVVVEHRFDGHVVRR T RGEL T E+ALE Sbjct 1 MRTPVVLVAGQGDTDDVTGLLLRRPGTVVVEHRFDGHVVRRNIITFRRGELSTAEEALEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLL+LLRRLHRRD V RIVVHLAPWLEP+PICWAI+HVRV VG GYPD Sbjct 61 AHGCVSCTIRNDLLILLRRLHRRDGVDRIVVHLAPWLEPEPICWAINHVRVRVGPGYPDA 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PA DVR+ AVVTCVD WL QSLG++EL DGRT AQVTVGQAEFAD+LVL P+PV + Sbjct 121 PAGRDVRIGAVVTCVDSANWLAQSLGDEELADGRTFAQVTVGQAEFADVLVLNRPDPVTL 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVL RLAPRARIT G+DRVELALA+LDD SRRGR+D PH LL G PPL DG V IVEF Sbjct 181 AVLPRLAPRARITVGLDRVELALANLDDYSRRGRSDHPHASLLGGRPPLGTDGGVGIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPF P+RLH AVD LLDGV+RTRGRLWLANRPDQVMWLESAGGGLRVA AGKWLAAM Sbjct 241 NARRPFRPERLHDAVDHLLDGVIRTRGRLWLANRPDQVMWLESAGGGLRVAWAGKWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + +EV + D ERRLFA++MW Y FGDRHTAMTVL CGAD +I L ALL+D EMA P Sbjct 301 SPAEVDHADPERRLFAEMMWEYRFGDRHTAMTVLACGADRAEITRVLTGALLTDREMARP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 Q W +Y DPFGDWH+DPCHE PD +G+FS H N GE Sbjct 361 QDWPAYDDPFGDWHEDPCHETPDESGQFSGHLNKGE 396 >gi|342859238|ref|ZP_08715892.1| CobW/P47K domain-containing protein [Mycobacterium colombiense CECT 3035] gi|342133479|gb|EGT86682.1| CobW/P47K domain-containing protein [Mycobacterium colombiense CECT 3035] Length=399 Score = 519 bits (1336), Expect = 4e-145, Method: Compositional matrix adjust. Identities = 263/397 (67%), Positives = 312/397 (79%), Gaps = 1/397 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQ TD V GALLR GT+VVEHRFDG VVRR T TLS G L + E LE Sbjct 1 MRTPVILVAGQRDTDPVVGALLRARGTLVVEHRFDGQVVRRTTTTLSGGVLASNETGLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DL+VLLR+LHRRD+V RIVVHLAPWLEP+PIC AI+H+RV V GY DG Sbjct 61 AHGCVSCTIRNDLMVLLRQLHRRDDVDRIVVHLAPWLEPEPICLAINHLRVRVAPGYIDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +AAVVTCVD WL Q+LGEDEL DGRT AQV +GQAEFAD++VL P P Sbjct 121 PAALDVSIAAVVTCVDSSAWLNQALGEDELDDGRTEAQVVIGQAEFADVVVLNQPNPFVA 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRL+PRAR+ G D +E AL L ++RRGR+D PH PLLAG PPL + G +++VEF Sbjct 181 AVLRRLSPRARVRVGADGIEDALNDLYRDARRGRSDDPHGPLLAGQPPLESRGPISLVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 ++RRPFHPQRLHA +DLLLDGV+RTRGRLWLA++PD+ MWLESAG GLRV+SAGKWLAA+ Sbjct 241 NSRRPFHPQRLHACLDLLLDGVIRTRGRLWLASQPDRAMWLESAGAGLRVSSAGKWLAAL 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 E+ +D ERR FA+L W GDRHTAMT+LVCGA P DI++AL+ ALL+D+EM P Sbjct 301 DDLELDGIDTERRAFAELSWDDRHGDRHTAMTILVCGAKPADILDALHGALLTDEEMRRP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAH-RNSGE 396 + W Y DPFGDWH++PC + +AA + H R G+ Sbjct 361 RDWIDYDDPFGDWHEEPCADRTEAADNAARHTRQDGD 397 >gi|169627439|ref|YP_001701088.1| cobalamin synthesis protein [Mycobacterium abscessus ATCC 19977] gi|169239406|emb|CAM60434.1| Probable cobalamin synthesis protein [Mycobacterium abscessus] Length=395 Score = 515 bits (1327), Expect = 4e-144, Method: Compositional matrix adjust. Identities = 263/398 (67%), Positives = 308/398 (78%), Gaps = 6/398 (1%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPV+LV+GQ TD VT L R GTVVV HRFDGH+V R A + RG TE LE Sbjct 1 MRTPVLLVSGQTDTDAVTQVLARDPGTVVVTHRFDGHIVMRSVAGI-RG---VTETVLEL 56 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIRDDLLVLLR+LHRRD+VGRIV+HL PWLE PICWAI+ V V VG G+ DG Sbjct 57 AHGCVSCTIRDDLLVLLRKLHRRDDVGRIVLHLEPWLEADPICWAINTVPVRVGPGFVDG 116 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAA DV++A VV+CVD WL Q+LG+DEL DGRTVAQV +GQAEFAD+L++ +PEP + Sbjct 117 PAARDVQIAGVVSCVDSANWLEQALGDDELADGRTVAQVVIGQAEFADVLLVRNPEPEVL 176 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 +VLRRLAPRARIT V RVE AL HL++++R GR D PH LLAG P LAADG V +VEF Sbjct 177 SVLRRLAPRARITARVGRVEQALDHLEEDARCGRADNPHGALLAGQPSLAADGRVELVEF 236 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPFHP RLHAA+D+LLDGV+RTRGRLWLA + +Q MWLESAGGGLRV++AGKWLAAM Sbjct 237 NARRPFHPLRLHAAIDMLLDGVIRTRGRLWLATQGEQAMWLESAGGGLRVSAAGKWLAAM 296 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + EV VD ERR FADLMW Y FGDRH AMTVLVCGAD ++++AL ALL+DDEMASP Sbjct 297 DSVEVQRVDPERRAFADLMWDYQFGDRHNAMTVLVCGADSREVLDALRGALLTDDEMASP 356 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAG--EFSAHRNSGE 396 W + DPFGDWH+DPC + +A + H G Sbjct 357 ADWDEFDDPFGDWHEDPCEHLSEAEAFLAYGDHNTEGN 394 >gi|254777315|ref|ZP_05218831.1| CobW/P47K domain-containing protein [Mycobacterium avium subsp. avium ATCC 25291] Length=398 Score = 505 bits (1300), Expect = 6e-141, Method: Compositional matrix adjust. Identities = 258/378 (69%), Positives = 299/378 (80%), Gaps = 0/378 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQ TD V GALLR GT+VVEHRFDGHVVRR TA L+ G L +TE LE Sbjct 1 MRTPVILVAGQRGTDPVVGALLRTPGTLVVEHRFDGHVVRRTTAVLTDGVLTSTECGLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLLVLLR+LHRRD+V RIVVHLAPWLEP+PIC AI+HVRV V G DG Sbjct 61 AHGCVSCTIRNDLLVLLRQLHRRDDVDRIVVHLAPWLEPEPICLAINHVRVRVAPGGVDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +AAVVTCVD WL Q+LGEDEL DGRT AQV +GQAEFAD++VL HP P Sbjct 121 PAALDVSIAAVVTCVDSSTWLSQALGEDELDDGRTHAQVVIGQAEFADVVVLDHPNPFLA 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRLAPRAR+ G D ++ AL +L ++RRGR D PH PLLAG PPL A G + +VEF Sbjct 181 AVLRRLAPRARVRVGADGIDDALNNLYRDARRGRVDDPHGPLLAGQPPLDARGPIRLVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 ++RRPFHP RLHA +DLLLDGV+RTRGRLWLA+R D+ MWLESAG GLRV+SAGKWLAAM Sbjct 241 NSRRPFHPGRLHACLDLLLDGVIRTRGRLWLASRADRAMWLESAGAGLRVSSAGKWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 E +D +RR+ A L W GDRHTAM +LVCGADP +I++AL AALL+ +E+ P Sbjct 301 TGPERDGIDAQRRVLAALGWDDRHGDRHTAMAILVCGADPAEILDALQAALLTHEELERP 360 Query 361 QRWQSYVDPFGDWHDDPC 378 W+ Y DPFGDWH++PC Sbjct 361 GEWEGYDDPFGDWHEEPC 378 >gi|254818908|ref|ZP_05223909.1| CobW/P47K domain-containing protein [Mycobacterium intracellulare ATCC 13950] Length=399 Score = 494 bits (1271), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 260/396 (66%), Positives = 310/396 (79%), Gaps = 0/396 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQ TD V GA+L+ GT+VVEHRFDGHVVRR TA+LS G L +TE+ LE Sbjct 1 MRTPVILVAGQRDTDAVVGAMLQTPGTLVVEHRFDGHVVRRTTASLSDGVLTSTENGLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLLVLLR+LHRRD+V RIVVHLAPWLEP+PIC AI HVRV V GY DG Sbjct 61 AHGCVSCTIRNDLLVLLRQLHRRDDVDRIVVHLAPWLEPEPICLAIKHVRVRVAPGYIDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +AAVVTCVD WL Q+LGE+EL DGRT AQV +GQAEFAD++VL P Sbjct 121 PAALDVAIAAVVTCVDSAAWLDQALGEEELDDGRTHAQVVIGQAEFADVVVLDRANPFVA 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRL+PRAR+ G +E AL +L ++RRGR+D PH PLLAG PPL + G +++VEF Sbjct 181 AVLRRLSPRARVRVGAGGIEDALNNLYRDARRGRSDDPHGPLLAGQPPLESRGPISLVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPFHPQRLHAA+DLLLDGV+RTRGRLWLA+ PD+ MWLESAG GLRV+SAGKWL AM Sbjct 241 NARRPFHPQRLHAALDLLLDGVIRTRGRLWLASNPDRAMWLESAGPGLRVSSAGKWLTAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + E VD ERR A L W GDRHTAM +LVCGA ++++AL ALL+++EM +P Sbjct 301 SGPERDGVDAERRALAALGWDDRHGDRHTAMAILVCGARTDEVLDALRGALLTEEEMRNP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 + W +Y DPFGDWH+DPC E+ +AA + H G+ Sbjct 361 RAWIAYDDPFGDWHEDPCAELTEAADNVAGHTQQGK 396 >gi|118464058|ref|YP_883996.1| CobW/P47K domain-containing protein [Mycobacterium avium 104] gi|118165345|gb|ABK66242.1| CobW/P47K C- domain protein [Mycobacterium avium 104] Length=381 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 246/360 (69%), Positives = 287/360 (80%), Gaps = 0/360 (0%) Query 19 GALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLR 78 GALLR +GT+VVEHRFDGHVVRR TA L+ G L +TE LE AHGCVSCTIR+DLLVLLR Sbjct 2 GALLRTSGTLVVEHRFDGHVVRRTTAVLTDGVLTSTECGLELAHGCVSCTIRNDLLVLLR 61 Query 79 RLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCV 138 +LHRRD+V RIVVHLAPWLEP+PIC AI+HVRV V G DGPAALDV +AAVVTCVD Sbjct 62 QLHRRDDVDRIVVHLAPWLEPEPICLAINHVRVRVAPGGVDGPAALDVSIAAVVTCVDSS 121 Query 139 RWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVAVLRRLAPRARITGGVDR 198 WL Q+LGEDEL DGRT AQV +GQAEFAD++VL HP P AVLRRLAPRAR+ G D Sbjct 122 TWLSQALGEDELDDGRTHAQVVIGQAEFADVVVLDHPNPFLAAVLRRLAPRARVRVGADG 181 Query 199 VELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLL 258 ++ AL +L ++RRGR D PH PLLAG PPL A G + +VEF++RRPFHP RLHA +DLL Sbjct 182 IDDALNNLYRDARRGRVDDPHGPLLAGQPPLDARGPIRLVEFNSRRPFHPGRLHACLDLL 241 Query 259 LDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADL 318 LDGV+RTRGRLWLA+R D+ MWLESAG GLRV+SAGKWLAAM E +D +RR+ A L Sbjct 242 LDGVIRTRGRLWLASRADRAMWLESAGAGLRVSSAGKWLAAMTGPERDGIDAQRRVLAAL 301 Query 319 MWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDDPC 378 W GDRHTAM +LVCGADP +I++AL AALL+D+E+ P WQ Y DPFGDWH++PC Sbjct 302 GWDDRHGDRHTAMAILVCGADPAEILDALQAALLTDEELERPGEWQGYDDPFGDWHEEPC 361 >gi|41409868|ref|NP_962704.1| hypothetical protein MAP3770 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398700|gb|AAS06320.1| hypothetical protein MAP_3770 [Mycobacterium avium subsp. paratuberculosis K-10] Length=398 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 250/378 (67%), Positives = 293/378 (78%), Gaps = 1/378 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQ TD V GALLR GT+VVEHR +GHVV R T L G L T E ALE Sbjct 1 MRTPVILVAGQKDTDPVVGALLRMPGTLVVEHRMEGHVVLRTTVMLQHGVLTTAESALEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLLVLLR+LHRR V RIVVHLAPWLEP+PIC AI HVRV V GY DG Sbjct 61 AHGCVSCTIRNDLLVLLRQLHRRAEVERIVVHLAPWLEPEPICVAISHVRVRVAAGYVDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +AAVVTCVD W+ Q+LG++EL DGRT AQV VGQAEFAD+LVL +P Sbjct 121 PAALDVSIAAVVTCVDSSVWVSQALGDEELDDGRTQAQVVVGQAEFADVLVLNRADPFTA 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 A LRRLAPRARI G + + L +L ++R+GR+D PH PLL+G PPL + G + +VEF Sbjct 181 AALRRLAPRARIQVGANGIGDTLNNLYRDARQGRSDDPHDPLLSGQPPLNSRGPINLVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 ARRPFHP+RLH +D++LDGV+RTRGRLWLA+RP MWLESAG GLRV+SAGKWLAA+ Sbjct 241 HARRPFHPRRLHECLDVVLDGVIRTRGRLWLASRPSHAMWLESAGAGLRVSSAGKWLAAL 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 A SE+A++D RR FA+L W GDRHTAMT+LVCGA+ +DI++ALN ALL+D E AS Sbjct 301 APSELAHIDPGRRAFAELEWDADHGDRHTAMTILVCGANASDILDALNGALLTDREFAS- 359 Query 361 QRWQSYVDPFGDWHDDPC 378 + W DPFGDWH+DPC Sbjct 360 RPWVFDDDPFGDWHEDPC 377 >gi|336460198|gb|EGO39102.1| putative GTPase, G3E family [Mycobacterium avium subsp. paratuberculosis S397] Length=398 Score = 485 bits (1248), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 249/378 (66%), Positives = 292/378 (78%), Gaps = 1/378 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVILVAGQ TD V GALLR GT+VVEHR +GHVV R T L G L T E ALE Sbjct 1 MRTPVILVAGQKDTDPVVGALLRMPGTLVVEHRMEGHVVLRTTVMLQHGVLTTAESALEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 AHGCVSCTIR+DLLVLLR+LHRR V RIVVHLAPWLEP+PIC AI HVRV V GY DG Sbjct 61 AHGCVSCTIRNDLLVLLRQLHRRAEVERIVVHLAPWLEPEPICVAISHVRVRVAAGYVDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +AAVVTCVD W+ Q+LG++EL DGRT AQV VGQAEFAD+LVL +P Sbjct 121 PAALDVSIAAVVTCVDSSVWVSQALGDEELDDGRTQAQVVVGQAEFADVLVLNRADPFTA 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 A LRRLAPRARI G + + L +L ++R+GR+D PH PLL+G PPL + G + +VEF Sbjct 181 AALRRLAPRARIQVGANGIGDTLNNLYRDARQGRSDDPHDPLLSGQPPLNSRGPINLVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 ARRPFHP+RLH +D++ DGV+RTRGRLWLA+RP MWLESAG GLRV+SAGKWLAA+ Sbjct 241 HARRPFHPRRLHECLDVVFDGVIRTRGRLWLASRPSHAMWLESAGAGLRVSSAGKWLAAL 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 A SE+A++D RR FA+L W GDRHTAMT+LVCGA+ +DI++ALN ALL+D E AS Sbjct 301 APSELAHIDPGRRAFAELEWDADHGDRHTAMTILVCGANASDILDALNGALLTDREFAS- 359 Query 361 QRWQSYVDPFGDWHDDPC 378 + W DPFGDWH+DPC Sbjct 360 RPWVFDDDPFGDWHEDPC 377 >gi|108801695|ref|YP_641892.1| cobalamin synthesis CobW-like protein [Mycobacterium sp. MCS] gi|119870846|ref|YP_940798.1| cobalamin synthesis CobW domain-containing protein [Mycobacterium sp. KMS] gi|108772114|gb|ABG10836.1| cobalamin synthesis CobW-like protein [Mycobacterium sp. MCS] gi|119696935|gb|ABL94008.1| cobalamin synthesis CobW domain protein [Mycobacterium sp. KMS] Length=395 Score = 463 bits (1191), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 237/396 (60%), Positives = 290/396 (74%), Gaps = 1/396 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVI+VAGQ ++ V L+ GTVVV HR DGHVV R AT ++ +E LE Sbjct 1 MRTPVIIVAGQGQSNAVCDVLMTEPGTVVVSHRLDGHVVVRTVATHRHKRVLVSEWPLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 GCV CT R DLLVLLR LHRR++V RIVV LAPWLEP+P+CWAI+++ V VG GY DG Sbjct 61 LKGCVGCTTRGDLLVLLRNLHRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PA+ DV + AVVT VD WL Q+LG+D+L D RTVAQV VGQAEFAD+LVLT PE + Sbjct 121 PASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVVVGQAEFADVLVLTEPERRTL 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRL PRARIT G D+ A+ +L+ ++RRGR +PH LLAG PPL ADG+V IVEF Sbjct 181 AVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPFHPQRLH A+D LLDGVVR RGR WLA+RPD V+W+ESAGGGL V AG+WLAAM Sbjct 241 NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + ++ AY ER A L W FGDRH A+T+L CGADP + AL+ ALL+DDE+ P Sbjct 301 SPNQRAYAAPERVALAALHWDERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 + W +Y DPFGDWH+DPC ++ D + ++ R+ GE Sbjct 361 ETWTAYEDPFGDWHEDPCDQV-DESTPAASQRHEGE 395 >gi|126437681|ref|YP_001073372.1| cobalamin synthesis CobW domain-containing protein [Mycobacterium sp. JLS] gi|126237481|gb|ABO00882.1| cobalamin synthesis CobW domain protein [Mycobacterium sp. JLS] Length=395 Score = 462 bits (1188), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 237/396 (60%), Positives = 290/396 (74%), Gaps = 1/396 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPVI+VAGQ ++ V L+ GTVVV HR DGHVV R AT ++ +E LE Sbjct 1 MRTPVIIVAGQGQSNAVCDVLMIEPGTVVVSHRLDGHVVVRTVATHRHQRVLVSEWPLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 GCV CT R DLLVLLR LHRR++V RIVV LAPWLEP+P+CWAI+++ V VG GY DG Sbjct 61 LKGCVGCTTRGDLLVLLRNLHRREDVTRIVVQLAPWLEPEPVCWAIENIAVHVGPGYIDG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PA+ DV + AVVT VD WL Q+LG+D+L D RTVAQV VGQAEFAD+LVLT PE + Sbjct 121 PASRDVAIDAVVTTVDTAVWLAQALGDDDLDDNRTVAQVVVGQAEFADVLVLTEPERRTL 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRL PRARIT G D+ A+ +L+ ++RRGR +PH LLAG PPL ADG+V IVEF Sbjct 181 AVLRRLTPRARITVGTDQFATAVRNLEPDARRGRGHSPHDALLAGEPPLRADGDVTIVEF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPFHPQRLH A+D LLDGVVR RGR WLA+RPD V+W+ESAGGGL V AG+WLAAM Sbjct 241 NARRPFHPQRLHRAIDDLLDGVVRIRGRAWLASRPDAVVWIESAGGGLHVGHAGEWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + ++ AY ER A L W FGDRH A+T+L CGADP + AL+ ALL+DDE+ P Sbjct 301 SPNQRAYAAPERVALAALHWDERFGDRHIALTLLACGADPQTVTGALSGALLTDDELTRP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 + W +Y DPFGDWH+DPC ++ D + ++ R+ GE Sbjct 361 ETWTAYEDPFGDWHEDPCDQV-DESTPAASQRHEGE 395 >gi|120406434|ref|YP_956263.1| cobalamin synthesis CobW domain-containing protein [Mycobacterium vanbaalenii PYR-1] gi|119959252|gb|ABM16257.1| cobalamin synthesis CobW domain protein [Mycobacterium vanbaalenii PYR-1] Length=373 Score = 434 bits (1117), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 231/372 (63%), Positives = 275/372 (74%), Gaps = 11/372 (2%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPV++VAGQ TD +TG LL GTV+VEHRFDGHVV R T + G L T ++ LE Sbjct 1 MRTPVVVVAGQSDTDGITGVLLDGAGTVLVEHRFDGHVVHRSTTVVQGGLLDTADEVLEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 + C+SCT+R+DLL LRRLHRR +V RI V L PW+EP+ +C+AI + Sbjct 61 TNCCLSCTVREDLLSHLRRLHRRPDVKRIAVRLGPWMEPEQVCFAITRL----------- 109 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAA DV +AAVVT VD WL Q+LG+DEL DGRTVAQV VGQ EFAD++VLT P+P V Sbjct 110 PAARDVAIAAVVTAVDTSTWLRQALGDDELDDGRTVAQVVVGQVEFADVVVLTGPDPDVV 169 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AV RRLAPRAR+ G R+ +ALA LD ++RRGR+D PH LL+G PPL A G V +VEF Sbjct 170 AVTRRLAPRARVAVGAQRLGVALADLDPDARRGRSDDPHASLLSGQPPLEAAGPVRLVEF 229 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +RRPFHP RLHAAVDLLLDGV+R+RGRLWLANRP +WLE+AGGGLRV GKWLAAM Sbjct 230 QSRRPFHPLRLHAAVDLLLDGVIRSRGRLWLANRPGHALWLETAGGGLRVTRTGKWLAAM 289 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + E+AYV ERR ADL+W YP GDRHT+MTVLVCGA+P DI++AL ALL+D EM P Sbjct 290 TSREIAYVGPERRAMADLIWGYPHGDRHTSMTVLVCGAEPADIIDALQGALLTDAEMQRP 349 Query 361 QRWQSYVDPFGD 372 Q W Y DPF D Sbjct 350 QDWGRYEDPFHD 361 >gi|118471890|ref|YP_890291.1| CobW/P47K domain-containing protein [Mycobacterium smegmatis str. MC2 155] gi|118173177|gb|ABK74073.1| CobW/P47K C- domain protein [Mycobacterium smegmatis str. MC2 155] Length=399 Score = 416 bits (1069), Expect = 4e-114, Method: Compositional matrix adjust. Identities = 240/377 (64%), Positives = 282/377 (75%), Gaps = 8/377 (2%) Query 6 ILVAGQDHTD----EVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEFA 61 +LVAGQD V LL+ GT++V H FDGHVV R ++ +++ LE Sbjct 1 MLVAGQDDARGTGRAVVEELLKAPGTLLVSHTFDGHVVVRTVSSSV----DSSQWVLELV 56 Query 62 HGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGP 121 HGCVSCT+RDDLL+LLRRLHRR +V RIVV + PWLEP+P+ WAID+V V VG GY DGP Sbjct 57 HGCVSCTVRDDLLILLRRLHRRADVTRIVVQMMPWLEPEPVRWAIDNVHVRVGPGYIDGP 116 Query 122 AALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVA 181 AA DV VAAVVTCVD WL Q+LGEDEL DGRT AQV VGQAE AD+LVL PE +A Sbjct 117 AARDVEVAAVVTCVDTAAWLEQALGEDELADGRTAAQVVVGQAEVADVLVLGEPEATTLA 176 Query 182 VLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFS 241 VLRRLAPRARIT G DR+ELALAHL+ ++ RGR +P LLAG PPL ADGEV IVEF+ Sbjct 177 VLRRLAPRARITVGPDRLELALAHLEPDTPRGRALSPRDSLLAGQPPLTADGEVRIVEFT 236 Query 242 ARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMA 301 ARRPFHP RLHAA+DLLLDGVVRTRGR WLANR +VMW+ESAGGGLRV++AGKWLAAM Sbjct 237 ARRPFHPVRLHAAIDLLLDGVVRTRGRAWLANRDAEVMWIESAGGGLRVSTAGKWLAAMN 296 Query 302 ASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQ 361 +SE+AY D + R A + W FGDRH ++ +LVCGA DI++AL ALL+D E A Q Sbjct 297 SSELAYTDPQWRALAAIDWDPSFGDRHVSLVMLVCGARTDDILDALRGALLTDAEFARRQ 356 Query 362 RWQSYVDPFGDWHDDPC 378 W+ Y DPFGDWH +PC Sbjct 357 EWRHYPDPFGDWHQEPC 373 >gi|120406280|ref|YP_956109.1| cobalamin synthesis CobW domain-containing protein [Mycobacterium vanbaalenii PYR-1] gi|119959098|gb|ABM16103.1| cobalamin synthesis CobW domain protein [Mycobacterium vanbaalenii PYR-1] Length=405 Score = 399 bits (1025), Expect = 4e-109, Method: Compositional matrix adjust. Identities = 224/391 (58%), Positives = 280/391 (72%), Gaps = 0/391 (0%) Query 2 RTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEFA 61 RTPV+LV+GQ+ TD+++ ALL ++GT+VV HRFDG VV R E T++ +E Sbjct 3 RTPVLLVSGQELTDQISEALLHKSGTLVVRHRFDGQVVLRSVCIRRGDEPHTSQWPIELM 62 Query 62 HGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGP 121 + CV CTIR DLLVLLRRLHRRD+V RIVVHL PWLEP+P+CW I++V V VG GY DGP Sbjct 63 NCCVDCTIRSDLLVLLRRLHRRDDVSRIVVHLPPWLEPEPLCWDINNVDVVVGPGYIDGP 122 Query 122 AALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVA 181 AA DVR+ AV+T V +WL +LG D L DGRTVAQV VGQAEFAD+L+L+ P+ A Sbjct 123 AARDVRIEAVITTVATGQWLTDALGADVLDDGRTVAQVVVGQAEFADVLLLSAPDRTTQA 182 Query 182 VLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFS 241 VL RLAPRA+I G +++ AL L D++RRG PH PLL+G PPL A+ V +VEF Sbjct 183 VLHRLAPRAQIITGTEQLGSALDALSDSARRGADHDPHEPLLSGEPPLVAEHGVKLVEFQ 242 Query 242 ARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMA 301 A RPFHP RLH A+D LLDGVVR RGR WLA++PD V+W+ESAGGGLRV AG+WLAA A Sbjct 243 AIRPFHPLRLHRAIDDLLDGVVRLRGRAWLASQPDVVLWIESAGGGLRVGHAGEWLAASA 302 Query 302 ASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQ 361 E A D ER + A L W FGDRH ++T L+CGADP + +L+AALL+DDE++ P Sbjct 303 IDEPADPDPERAVLASLRWDEQFGDRHISLTALICGADPEAVTASLSAALLTDDELSRPD 362 Query 362 RWQSYVDPFGDWHDDPCHEMPDAAGEFSAHR 392 W + DPFG+WH+DPC + A G + R Sbjct 363 LWAHWEDPFGEWHEDPCEGLDKADGAATRDR 393 >gi|145221905|ref|YP_001132583.1| cobalamin synthesis CobW domain-containing protein [Mycobacterium gilvum PYR-GCK] gi|315446359|ref|YP_004079238.1| GTPase, G3E family [Mycobacterium sp. Spyr1] gi|145214391|gb|ABP43795.1| cobalamin synthesis CobW domain protein [Mycobacterium gilvum PYR-GCK] gi|315264662|gb|ADU01404.1| predicted GTPase, G3E family [Mycobacterium sp. Spyr1] Length=370 Score = 383 bits (983), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 208/374 (56%), Positives = 254/374 (68%), Gaps = 11/374 (2%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 MRTPV++V GQ T ++ LL T +VEH +GHVV R T L RG ++ +E Sbjct 1 MRTPVVVVTGQSDTGDIGDLLLADGATALVEHHVEGHVVHRTTTVLRRGVVVKAVSVVEM 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 +GC SC +R+DL+ L RLH R +V RI V L+PW+EP+P+C A+ Sbjct 61 TNGCPSCAVREDLVDHLCRLHLRPDVARIAVLLSPWMEPEPVCVALTRSTAARHVAVSAV 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 A +D V WL Q+LG+DEL DGRTVAQV VGQ EFAD++VLT + Sbjct 121 VATVDTSV-----------WLHQALGDDELDDGRTVAQVVVGQVEFADVVVLTEAHRDTL 169 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AV+RRLAP ARIT GV R LALA+LD ++RRGR + PH LLAG PPL G V +VEF Sbjct 170 AVVRRLAPAARITVGVSRFTLALANLDADARRGRGNDPHGSLLAGQPPLEPAGRVRLVEF 229 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +ARRPFHP RLHAAVDLLL+GVVR+RGRLWLA+ PD + L+SAGGGL V AGKWLAAM Sbjct 230 AARRPFHPSRLHAAVDLLLEGVVRSRGRLWLAHLPDMAVGLDSAGGGLLVTRAGKWLAAM 289 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 + E+AYV ERR AD+MW +GDRHT+MTVLVCGADP +IV+AL ALL+D EM P Sbjct 290 TSRELAYVGAERRAMADMMWDDRYGDRHTSMTVLVCGADPAEIVSALRGALLTDAEMGRP 349 Query 361 QRWQSYVDPFGDWH 374 Q W + DPFGDWH Sbjct 350 QDWPRFDDPFGDWH 363 >gi|41409845|ref|NP_962681.1| hypothetical protein MAP3747c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398677|gb|AAS06297.1| hypothetical protein MAP_3747c [Mycobacterium avium subsp. paratuberculosis K-10] Length=406 Score = 381 bits (979), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 203/388 (53%), Positives = 261/388 (68%), Gaps = 1/388 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 M TPV+L+ G+ T V AL GT V+ H DGHVVRR + L G ++ LE Sbjct 1 MHTPVVLLTGRGCTGRVAAALRETPGTAVISHTLDGHVVRRRVSMLRAGAPWDSDWILEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 + TI DDLL+LLRR+HRR +V R+VV L E + IC+AI+H VCVG GY DG Sbjct 61 GNADPGRTIHDDLLILLRRVHRRQDVDRVVVLLDERTELELICYAINHTPVCVGPGYADG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +++VVTCVD WL ++G+DEL D R+ AQ V QAEFAD+LVL+ PE Sbjct 121 PAALDVHISSVVTCVDTDSWLAHAMGDDELDDHRSAAQAVVDQAEFADVLVLSKPERRTE 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRLAPR+RIT + +E L +L +RRG PH LL G PPL ++ V++++F Sbjct 181 AVLRRLAPRSRITCDITSIESILRNLHPLARRGADFDPHESLLTGQPPLVSEAGVSLLDF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +A RPFHP RLH A+D+LL+GVVRTRGR+WLA++PD V+W+ESAG LRV + G+WLAAM Sbjct 241 TATRPFHPARLHTAIDVLLEGVVRTRGRVWLASQPDTVVWIESAGMELRVGNVGRWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 ASE+A D +RR+ A W GDRH AMT+L CGADP +I+ L ALL+D+E + P Sbjct 301 DASEMAAADADRRIMAAARWDDQHGDRHVAMTILTCGADPGEILRILRWALLTDEEFSQP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMP-DAAGE 387 RW +Y DPFGDW P + +AGE Sbjct 361 GRWANYADPFGDWRAGPFESVSYGSAGE 388 >gi|336460146|gb|EGO39051.1| putative GTPase, G3E family [Mycobacterium avium subsp. paratuberculosis S397] Length=406 Score = 380 bits (976), Expect = 2e-103, Method: Compositional matrix adjust. Identities = 203/388 (53%), Positives = 260/388 (68%), Gaps = 1/388 (0%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEF 60 M TPV+L+ G+ T V AL GT V+ H DGHVVRR + L G ++ LE Sbjct 1 MHTPVVLLTGRGCTGRVAAALRETPGTAVISHTLDGHVVRRRVSMLRAGAPWDSDWILEL 60 Query 61 AHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG 120 + TI DDLL+LLRR+HRR +V R+VV L E + IC+AI+H VCVG GY DG Sbjct 61 GNADPGRTIHDDLLILLRRVHRRQDVDRVVVLLDERTELELICYAINHTPVCVGPGYADG 120 Query 121 PAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV 180 PAALDV +++VVTCVD WL ++G+DEL D R+ AQ V QAEFAD+LVL+ PE Sbjct 121 PAALDVHISSVVTCVDTDSWLAHAMGDDELDDHRSAAQAVVDQAEFADVLVLSKPERRTE 180 Query 181 AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEF 240 AVLRRLAPR+RIT + +E L L +RRG PH LL G PPL ++ V++++F Sbjct 181 AVLRRLAPRSRITCDITSIESILRDLHPLARRGADFDPHESLLTGQPPLVSEAGVSLLDF 240 Query 241 SARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAM 300 +A RPFHP RLH A+D+LL+GVVRTRGR+WLA++PD V+W+ESAG LRV + G+WLAAM Sbjct 241 TATRPFHPARLHTAIDVLLEGVVRTRGRVWLASQPDTVVWIESAGMELRVGNVGRWLAAM 300 Query 301 AASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASP 360 ASE+A D +RR+ A W GDRH AMT+L CGADP +I+ L ALL+D+E + P Sbjct 301 DASEMAAADADRRIMAAARWDDQHGDRHVAMTILTCGADPGEILRILRWALLTDEEFSQP 360 Query 361 QRWQSYVDPFGDWHDDPCHEMP-DAAGE 387 RW +Y DPFGDW P + +AGE Sbjct 361 GRWANYADPFGDWRAGPFESVSYGSAGE 388 >gi|226365091|ref|YP_002782874.1| hypothetical protein ROP_56820 [Rhodococcus opacus B4] gi|226243581|dbj|BAH53929.1| hypothetical protein [Rhodococcus opacus B4] Length=421 Score = 359 bits (922), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 205/389 (53%), Positives = 250/389 (65%), Gaps = 11/389 (2%) Query 2 RTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFD---GHVVRRMTATLSRGELITTEDAL 58 RTP+ILV+G E L R GTVVV H D VVRR TL G L Sbjct 17 RTPLILVSGWSGPAEEAARSLLREGTVVVHHDLDLVHEGVVRRTVTTLESGAPRERLRIL 76 Query 59 EFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYP 118 E AHGC+SCT+R+DLL L+RRLH R +V RIV+HL LEP+ +CWA++HV V G Sbjct 77 ELAHGCISCTLREDLLPLIRRLHTRSSVQRIVLHLDRGLEPEAVCWAVEHVSVSGVVGQI 136 Query 119 DGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHP--- 175 DGPA+ DVRV VVTC+D WL + G+D L D RTVAQV VGQ +FAD LV++ Sbjct 137 DGPASRDVRVDGVVTCLDAGSWLADATGDDALDDDRTVAQVAVGQVDFADALVVSGSAGD 196 Query 176 ---EPVAVAVLRRLAPRARIT--GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLA 230 + AVL RLAP A I+ GG VE L + +RRG H+PLL G PPL+ Sbjct 197 GWQQARLHAVLARLAPGAPISWGGGTPDVERLLLDIPAGARRGEPSHAHSPLLRGQPPLS 256 Query 231 ADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRV 290 D V +VEF+A RPFHP+RLH AVD+LLDGVV +RGR+W+A +PD+ +WLESAGGGLRV Sbjct 257 HDCGVMLVEFTATRPFHPERLHEAVDVLLDGVVTSRGRVWVATQPDEALWLESAGGGLRV 316 Query 291 ASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAA 350 ASA +WLAAM E + RR A L W FGDRHT+M VLV ADPT+I L A Sbjct 317 ASADRWLAAMTPEEQEQAGVARRAMAALCWDERFGDRHTSMVVLVHAADPTEIDRTLQWA 376 Query 351 LLSDDEMASPQRWQSYVDPFGDWHDDPCH 379 L++DDE+A WQS+ DPFG +H+DPC Sbjct 377 LVTDDELADEAAWQSWPDPFGQFHEDPCE 405 >gi|111022584|ref|YP_705556.1| hypothetical protein RHA1_ro05618 [Rhodococcus jostii RHA1] gi|110822114|gb|ABG97398.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=412 Score = 357 bits (915), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 209/399 (53%), Positives = 253/399 (64%), Gaps = 13/399 (3%) Query 2 RTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFD---GHVVRRMTATLSRGELITTEDAL 58 RTP+ILV+G + E L R GTVVV H D VVRR TL G L Sbjct 8 RTPLILVSGWNGPTEDAARSLLRDGTVVVHHDLDLVHEGVVRRTVTTLESGAPRERLGIL 67 Query 59 EFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYP 118 E AHGC+SCT+R+DLL LLRRLH R +V RIV+HL LEP+ +CWA++HV V G Sbjct 68 ELAHGCISCTLREDLLPLLRRLHTRSSVQRIVLHLDRRLEPEAVCWAVEHVAVSGVVGQI 127 Query 119 DGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTH---- 174 DGPA+ DVRV V+TC+D WL + G+D L D RTVAQV VGQ +FAD LV++ Sbjct 128 DGPASRDVRVDGVITCLDAGSWLADATGDDALDDDRTVAQVAVGQVDFADALVVSGNAGD 187 Query 175 --PEPVAVAVLRRLAPRARIT--GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLA 230 + AVL RLAP A I G VE L + +RRG H+PLL G PPL+ Sbjct 188 GWQQARLHAVLTRLAPGAPIVWDGDAPDVERLLLDIPAGARRGELSHAHSPLLRGQPPLS 247 Query 231 ADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRV 290 D V +VEF+A RPFHP+RLH AVD+LLDGVV +RGR+W+A +PD+ +WLESAGGGLRV Sbjct 248 PDCGVMLVEFTATRPFHPERLHEAVDVLLDGVVTSRGRVWVATQPDEALWLESAGGGLRV 307 Query 291 ASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAA 350 ASA +WLAAM E V RR A L W FGDRHT+M VLV ADPT+I L A Sbjct 308 ASADRWLAAMTPEEQEQVPTARRAMAALCWDERFGDRHTSMVVLVHAADPTEIDRTLQWA 367 Query 351 LLSDDEMASPQRWQSYVDPFGDWHDDPCH--EMPDAAGE 387 L++DDE+A WQS+ DPFG +H+DPC E P A E Sbjct 368 LVTDDELADEAAWQSWPDPFGQFHEDPCESSESPYAEPE 406 >gi|229495110|ref|ZP_04388856.1| CobW/P47K domain protein [Rhodococcus erythropolis SK121] gi|229318041|gb|EEN83916.1| CobW/P47K domain protein [Rhodococcus erythropolis SK121] Length=417 Score = 352 bits (903), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 200/410 (49%), Positives = 252/410 (62%), Gaps = 15/410 (3%) Query 2 RTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFD---GHVVRRMTATL-----SRGELIT 53 RTP++LVAG + T L RTGTV+V H VVRR ++ S G + Sbjct 8 RTPLVLVAGMSESTPHTARALLRTGTVLVHHDLSHVREGVVRRTVTSMTGSAGSAGTVSE 67 Query 54 TEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCV 113 E LE AHGCVSCT+R+DLL LLRRLH +V RIV+ L LEP+ +CWAI+HV V Sbjct 68 RETILELAHGCVSCTLREDLLPLLRRLHSHSSVQRIVLLLDRQLEPEALCWAIEHVVVTG 127 Query 114 GHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLT 173 G DGPA DVRV AVVTC+D WL + G++ L D RT+AQV VGQ +FAD LVL Sbjct 128 VVGQLDGPAQRDVRVDAVVTCIDAATWLADATGDEALDDDRTLAQVVVGQVDFADALVLR 187 Query 174 HPEPV-------AVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGL 226 + + AVL R+APR + D +E L + ++RRG H+PLL Sbjct 188 GSDALDGWQRSRLNAVLARIAPRVPVFDEGDDIEALLLEVPADARRGELADAHSPLLRRQ 247 Query 227 PPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGG 286 PPL DG V +VEF+A RPFHP RLH A+D+LL+GVV +RGR+W+A +P + +WLESAGG Sbjct 248 PPLDDDGGVMLVEFTANRPFHPGRLHEAIDVLLEGVVYSRGRVWVATQPGEALWLESAGG 307 Query 287 GLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNA 346 GLRVASA WLAAM E V ERR A L W FGDR T+M VL CGA+P +I Sbjct 308 GLRVASADTWLAAMTPEERDRVPAERRALAALKWDERFGDRDTSMVVLTCGANPLEIDRT 367 Query 347 LNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 L AL++DDE+A W ++ DPFG++H+DPC E E + R E Sbjct 368 LQHALVTDDELADEASWATWEDPFGEFHEDPCDESESPYAETESTREGNE 417 >gi|312138608|ref|YP_004005944.1| hypothetical protein REQ_11600 [Rhodococcus equi 103S] gi|311887947|emb|CBH47259.1| conserved hypothetical protein [Rhodococcus equi 103S] Length=409 Score = 345 bits (884), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 203/404 (51%), Positives = 250/404 (62%), Gaps = 13/404 (3%) Query 2 RTPVILVAG-QDHTDEVTGALLRRTGTVVVEHRF---DGHVVRRMTATLSRGELITTEDA 57 RTP++LV+G + +E + L GTVV+ H VRR T + + T + Sbjct 8 RTPLVLVSGWRGPVEETARSFLDGQGTVVIRHDLADLGQGAVRRTVTTGTAAVPVVTTEI 67 Query 58 LEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGY 117 LE AHGCVSCT+R DLL LLR+LH R V R+V+ L P LEP+ +CWAI+HV V G Sbjct 68 LELAHGCVSCTLRFDLLPLLRKLHARSTVDRVVLELDPALEPEAVCWAIEHVPVVGVVGR 127 Query 118 PDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEP 177 DGPAA D+RV AVVTCVD W G+++L D RTVAQV VGQ FAD LV+ HP Sbjct 128 IDGPAARDIRVEAVVTCVDVDGWWDAVTGDEDLDDDRTVAQVAVGQVAFADALVV-HPSA 186 Query 178 -------VAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLA 230 AVL RLAP A + D L L + ++RRGR D H+PLL G PPL Sbjct 187 RDPWLTHKVRAVLARLAPGAPVVSAADGPSL-LPRVGADARRGRVDGAHSPLLRGCPPLE 245 Query 231 ADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRV 290 + VA+VEF+ARRPFHP RLH A+D+LLDGVV RGRLWLA RPD +WLESAGGGLRV Sbjct 246 EEHGVALVEFTARRPFHPGRLHEAIDVLLDGVVTARGRLWLATRPDAALWLESAGGGLRV 305 Query 291 ASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAA 350 A+A +WLA M E VD ERR A L W FGDR T+M VLV +P +I AL A Sbjct 306 AAADRWLADMTDDETELVDPERRALAALRWDDRFGDRDTSMVVLVHDVEPEEITAALGWA 365 Query 351 LLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNS 394 L+++ E+A W ++ DPFG++H DPC E P A E + S Sbjct 366 LVTERELADEAAWPTWDDPFGEFHTDPCAEAPLGAFEKNGENAS 409 >gi|325676325|ref|ZP_08156004.1| cobalamin synthesis CobW family protein [Rhodococcus equi ATCC 33707] gi|325552886|gb|EGD22569.1| cobalamin synthesis CobW family protein [Rhodococcus equi ATCC 33707] Length=411 Score = 342 bits (878), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 203/404 (51%), Positives = 250/404 (62%), Gaps = 13/404 (3%) Query 2 RTPVILVAG-QDHTDEVTGALLRRTGTVVVEHRF---DGHVVRRMTATLSRGELITTEDA 57 RTP++LV+G + +E + L GTVV+ H VVRR T + + T + Sbjct 10 RTPLVLVSGWRGPVEETARSFLDGQGTVVIRHDLADLGQGVVRRTVTTGTAAVPVVTTEI 69 Query 58 LEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGY 117 LE AHGCVSCT+R DLL LLR+LH R V R+V+ L P LEP+ +CWAI+HV V G Sbjct 70 LELAHGCVSCTLRFDLLPLLRKLHARSTVDRVVLELDPALEPEAVCWAIEHVPVVGVVGR 129 Query 118 PDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEP 177 DGPAA D+RV AVVTCVD W G+++L D RTVAQV VGQ FAD LV+ HP Sbjct 130 IDGPAARDIRVEAVVTCVDVDGWWDAVTGDEDLDDDRTVAQVAVGQVAFADALVV-HPSA 188 Query 178 -------VAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLA 230 AVL RLAP A + D L L + ++RRGR D H+PLL G PPL Sbjct 189 RDPWLTHKVRAVLARLAPGAPVVSAADGPSL-LPRVGADARRGRVDGAHSPLLRGRPPLE 247 Query 231 ADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRV 290 + VA+VEF+ARRPFHP RLH A+D+LLDGVV RGRLWLA RPD +WLESAGGGLRV Sbjct 248 EEHGVALVEFTARRPFHPGRLHEAIDVLLDGVVTARGRLWLATRPDAALWLESAGGGLRV 307 Query 291 ASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAA 350 A+A +WLA M E VD RR A L W FGDR T+M VLV +P +I AL A Sbjct 308 AAADRWLADMTDDETELVDPGRRALAALRWDDRFGDRDTSMVVLVHDVEPEEITAALGWA 367 Query 351 LLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNS 394 L+++ E+A W ++ DPFG++H DPC E P A E + S Sbjct 368 LVTERELADEAAWPTWDDPFGEFHTDPCTEAPLGAFEKNGENAS 411 >gi|226307889|ref|YP_002767849.1| hypothetical protein RER_44020 [Rhodococcus erythropolis PR4] gi|226187006|dbj|BAH35110.1| conserved hypothetical protein [Rhodococcus erythropolis PR4] Length=417 Score = 338 bits (867), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 198/410 (49%), Positives = 253/410 (62%), Gaps = 15/410 (3%) Query 2 RTPVILVAGQDHTDEVTGALLRRTGTVVVEHRF----DGHVVRRMTA----TLSRGELIT 53 RTP++LVAG + T L RTGTV+V H +G V R +T+ T S G + Sbjct 8 RTPLVLVAGMSESTPHTARALLRTGTVLVHHDLSHVREGVVRRTVTSMTGGTGSAGTVSE 67 Query 54 TEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCV 113 E LE AHGCVSCT+R+DLL LLRRLH +V RIV+ L LEP+ +CWAI+HV V Sbjct 68 RETILELAHGCVSCTLREDLLPLLRRLHSHSSVQRIVLLLDRQLEPEALCWAIEHVVVTG 127 Query 114 GHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLT 173 G DGPA D RV AVVTC+D WL + G++ L D RT+AQV VGQ +FAD LVL Sbjct 128 VVGQVDGPAQRDCRVDAVVTCIDAQTWLADATGDEALDDDRTLAQVVVGQVDFADALVLR 187 Query 174 HPEPV-------AVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGL 226 + + AVL R+APR + D +E L + ++RRG H+PLL Sbjct 188 GSDGLDGWQRSRLNAVLARIAPRVPVFDEGDDIEALLLEVPADARRGELADAHSPLLRRQ 247 Query 227 PPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGG 286 PPL DG V +VEF+A RPFHP RLH A+D+LL+GVV +RGR+W+A +P + +WLESAGG Sbjct 248 PPLDDDGGVMLVEFTANRPFHPGRLHEAIDVLLEGVVYSRGRVWVATQPGEALWLESAGG 307 Query 287 GLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNA 346 GLRVASA WLAAM + V ERR A L W FGDR T+M VL CGA+P +I Sbjct 308 GLRVASADTWLAAMTPQQRERVPAERRALAALKWDERFGDRDTSMVVLTCGANPLEIDRT 367 Query 347 LNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGE 396 L AL++D+E+A W ++ DPFG++H+DPC E E + R E Sbjct 368 LQHALVTDEELADEASWTTWEDPFGEFHEDPCDESESPYAETESTREGNE 417 >gi|333921229|ref|YP_004494810.1| hypothetical protein AS9A_3572 [Amycolicicoccus subflavus DQS3-9A1] gi|333483450|gb|AEF42010.1| hypothetical protein AS9A_3572 [Amycolicicoccus subflavus DQS3-9A1] Length=422 Score = 334 bits (857), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 196/407 (49%), Positives = 245/407 (61%), Gaps = 23/407 (5%) Query 1 MRTPVILVAGQDHTDEVTGALLRRTGTVVVEH---RFDGHVVRRMTATLSRGELITTEDA 57 RTPV+LV G L+R GT VV H VVRR T + Sbjct 4 QRTPVVLVCGWQGDSRAVAQALQREGTTVVHHDLSEVSTGVVRRTLMTTNGITPREKTTI 63 Query 58 LEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGY 117 LE AHGCVSCT+R+DLL LLRRLH R V RIV+ + P LEP+ + WAI+HV V G+ Sbjct 64 LELAHGCVSCTLREDLLPLLRRLHTRSRVERIVLLIDPVLEPEALSWAIEHVVVSGMVGH 123 Query 118 PDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELP---------DGRTVAQVTVGQAEFAD 168 DGPA DVRV A VTC+D WL + +D L D RTVAQV VGQA+FAD Sbjct 124 VDGPAGQDVRVDATVTCIDAATWLSDATSDDTLDERGIVASNDDDRTVAQVVVGQADFAD 183 Query 169 LLVLTH------PEPVAVAVLRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTP 218 +V++ + AVL RLAP A I GG E LA++ SRRG Sbjct 184 AIVISGAANDGWEQAKLNAVLARLAPGAPIAWTGAGGSIDAERLLANIPAPSRRGEITDA 243 Query 219 HTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQV 278 H+P+L G PPL +D V IVEFSA+RPFHP+RLH ++D LLDGV+ TRGR W+A++PDQV Sbjct 244 HSPMLRGEPPLDSDCGVQIVEFSAQRPFHPERLHESIDTLLDGVICTRGRFWVASQPDQV 303 Query 279 MWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGA 338 +W+ESAGGGLR+A++G WL AM + A + ER A L W FGDR +M VLV A Sbjct 304 LWMESAGGGLRIAASGLWLDAMTREQQAEQNPERHAIAALRWDPRFGDRDCSMAVLVHDA 363 Query 339 DPTDIVNALNAALLSDDEMA-SPQRWQSYVDPFGDWHDDPCHEMPDA 384 +P I AL +ALL+D+E+A W ++ DPFG WH+DPC E+ A Sbjct 364 EPQRITEALQSALLTDEELALGEAEWATWNDPFGQWHEDPCDELAGA 410 >gi|343928747|ref|ZP_08768192.1| hypothetical protein GOALK_120_01740 [Gordonia alkanivorans NBRC 16433] gi|343761496|dbj|GAA15118.1| hypothetical protein GOALK_120_01740 [Gordonia alkanivorans NBRC 16433] Length=459 Score = 277 bits (708), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 201/431 (47%), Positives = 250/431 (59%), Gaps = 34/431 (7%) Query 2 RTPVILVAGQDH--TDEVTGALLRRTGTVVVEHRF----DGHVVRRMTATLSRGELITTE 55 RTPVILV G D + + AL GTV V H DG V+R +T S G Sbjct 21 RTPVILVTGLDRPTSRRIGDALTSDPGTVQVHHDLSGVGDGRVIRTLTWRESDGRRREGV 80 Query 56 DALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGH 115 +E AHGCVSCT+R+DLL LLRRLHRR +V RIV+ L P LEP+ I W+I+HV V Sbjct 81 TVIELAHGCVSCTLREDLLPLLRRLHRRSSVRRIVLTLDPILEPERIAWSIEHVVVDDEP 140 Query 116 GYPDGPAALDVRVAAVVTCVDCVRWLPQSLGE----DELP----DGRTVAQVTVGQAEFA 167 P PAALDVRV + + V WL + G+ + LP D RT+AQV VGQ FA Sbjct 141 DTPAAPAALDVRVESTIVSVAEELWLHHATGDLGLCEVLPVPPDDERTLAQVAVGQVAFA 200 Query 168 DLLVLTHPEPVA---------VAVLRRLAPRARITGGVDR-------VELALAHLDDNSR 211 D LV+ +P A +AVL+RL+PRA + + VE +A + +SR Sbjct 201 DALVVVGSDPAARDAWESARLMAVLKRLSPRAPMMFELPERPLTPLLVEQLVAAIPPSSR 260 Query 212 RGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWL 271 RGR D PH PLL P L D V +EF RP HP RLH A+D LLDGVV RGRLW+ Sbjct 261 RGRIDGPHDPLLVDQPSLDPDCGVTWMEFHTDRPLHPGRLHDAIDSLLDGVVCARGRLWV 320 Query 272 ANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAM 331 A +PD+ +WLESAGGGLRVA G+WLAAM E+A V ERR L W FGDRH+++ Sbjct 321 ATQPDEALWLESAGGGLRVAPGGRWLAAMDDDELARVSPERRALGALRWDDTFGDRHSSL 380 Query 332 TVLVCGADPTDIVNALNAALLSDDEMASPQR-WQSYVDPFGDWHDDPCHEMPDAAGEF-- 388 VLV DP +I AL AA L++ E+A+ Q W + DPFG +H DPC ++ A Sbjct 381 VVLVHRGDPDEIDEALRAACLNEVELAAGQDFWDTLDDPFGRFHADPCDDVDVEAPMVDA 440 Query 389 -SAHRNSGESR 398 +A R SG R Sbjct 441 PAADRRSGNGR 451 >gi|54026948|ref|YP_121190.1| hypothetical protein nfa49740 [Nocardia farcinica IFM 10152] gi|54018456|dbj|BAD59826.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=441 Score = 276 bits (707), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 187/381 (50%), Positives = 230/381 (61%), Gaps = 32/381 (8%) Query 26 GTVVVEHRFDG---HVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHR 82 GTVVV H + VVRR T+ L TTE LE AHGCVSCT+R DLL LL L Sbjct 44 GTVVVRHHLEDLREGVVRRTLRTV----LATTETVLELAHGCVSCTLRADLLPLLCTLAA 99 Query 83 RDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLP 142 R++V RIV+ L P E + +C AI+ V V G DGPAA DVR+ AV+TCVD WL Sbjct 100 RESVHRIVLELDPAFEAEAVCQAIEDVVVTGVVGRVDGPAARDVRIEAVLTCVDAASWLA 159 Query 143 QSLGEDELP--------DGRTVAQVTVGQAEFADLLVLTHP--EPVA----VAVLRRLAP 188 + GED L D RTVAQV VGQ +FAD LV P +P+ AVL RL P Sbjct 160 DATGEDTLAERGLATADDDRTVAQVAVGQVDFADALVALGPASDPIEHDRLTAVLARLVP 219 Query 189 RARITG-------GVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFS 241 A +T +E L + +SRRGR H PLL G P L + V +VEF+ Sbjct 220 EAPVTWVDSPDAITAAEIEALLTRIPAHSRRGRVFDAHAPLLRGQPSLLTEHGVTLVEFA 279 Query 242 ARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMA 301 A RPFHP RLH A+D+LL+GVV RGRLWLA +PD+V+WLESAGGGLRV AG WLAAM+ Sbjct 280 ASRPFHPARLHDALDVLLEGVVTARGRLWLATQPDEVVWLESAGGGLRVGGAGPWLAAMS 339 Query 302 ASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEM---- 357 A + D RR A L W FGDRH ++ +L ADP +I AL+ AL+ DDE+ Sbjct 340 AEDYERADPTRRALAALGWDERFGDRHISLVILAHEADPAEIRRALHWALVEDDELRLVD 399 Query 358 ASPQRWQSYVDPFGDWHDDPC 378 +P+R + DPFG+WH++PC Sbjct 400 RAPERVARWEDPFGEWHEEPC 420 >gi|134097361|ref|YP_001103022.1| cobalamin synthesis CobW-like protein [Saccharopolyspora erythraea NRRL 2338] gi|133909984|emb|CAM00096.1| cobalamin synthesis CobW-like protein [Saccharopolyspora erythraea NRRL 2338] Length=437 Score = 271 bits (692), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 189/424 (45%), Positives = 238/424 (57%), Gaps = 40/424 (9%) Query 2 RTPVILVAGQDHTDEVTGALLRRTG-----TVVVEH---RFDGHVVRRMTATLSRGELIT 53 R P+++V+G H ++V A TVVV+H VVRR +L Sbjct 22 RVPLVVVSGI-HEEQVARAAEAVRARDAARTVVVQHDLREISQGVVRRHVRHGDHEQLAV 80 Query 54 TEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCV 113 LE HGCVSCT+R+D L LLRRL +V RIVV L P LEP+ ICWA+ HV V Sbjct 81 ----LELVHGCVSCTLREDFLPLLRRLCAAPDVERIVVRLDPALEPEAICWALQHVVV-- 134 Query 114 GHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELP---------DGRTVAQVTVGQA 164 G DV V AV+ VD WL + GEDEL D RTVAQV VGQ Sbjct 135 ----DGGTLDTDVAVEAVIAVVDRPSWLSDASGEDELAERGLAGSPDDERTVAQVVVGQV 190 Query 165 EFADLLVLTHP------EPVAVAVLRRL---APRARITGGVDRVELALAHLDDNSRRGRT 215 EFAD +VL E AV+ RL APR + G +D +L LA + +RRGR Sbjct 191 EFADAVVLAGEAEDRWQEVRTEAVISRLTPTAPRGHLDG-LDPADL-LARVPAEARRGRI 248 Query 216 DTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRP 275 D PH PLL G P L ++ V +V F RRPFHPQRLH +D+LLDGVVRTRGR W+A++P Sbjct 249 DWPHGPLLRGQPSLESEAGVCVVLFEERRPFHPQRLHEVLDVLLDGVVRTRGRAWVASQP 308 Query 276 DQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLV 335 +WLESAGGGL V AG WLAA+ ++ V ER++ A L W +GDR + V+ Sbjct 309 GAALWLESAGGGLNVGHAGPWLAALDTAQWDEVSAERQVRASLNWDDYYGDRMQELVVIA 368 Query 336 CGADPTDIVNALNAALLSDDEMASPQR-WQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNS 394 ADP +I AL +ALL+D E+A + W Y DPFG+WH DPC +M G A ++ Sbjct 369 HEADPREITRALRSALLTDAEIAEGEAVWAGYEDPFGEWHTDPCPDMGAGTGSEPATGSA 428 Query 395 GESR 398 +R Sbjct 429 DAAR 432 >gi|291009080|ref|ZP_06567053.1| cobalamin synthesis CobW-like protein [Saccharopolyspora erythraea NRRL 2338] Length=429 Score = 270 bits (691), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 189/424 (45%), Positives = 238/424 (57%), Gaps = 40/424 (9%) Query 2 RTPVILVAGQDHTDEVTGALLRRTG-----TVVVEH---RFDGHVVRRMTATLSRGELIT 53 R P+++V+G H ++V A TVVV+H VVRR +L Sbjct 14 RVPLVVVSGI-HEEQVARAAEAVRARDAARTVVVQHDLREISQGVVRRHVRHGDHEQLAV 72 Query 54 TEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCV 113 LE HGCVSCT+R+D L LLRRL +V RIVV L P LEP+ ICWA+ HV V Sbjct 73 ----LELVHGCVSCTLREDFLPLLRRLCAAPDVERIVVRLDPALEPEAICWALQHVVV-- 126 Query 114 GHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELP---------DGRTVAQVTVGQA 164 G DV V AV+ VD WL + GEDEL D RTVAQV VGQ Sbjct 127 ----DGGTLDTDVAVEAVIAVVDRPSWLSDASGEDELAERGLAGSPDDERTVAQVVVGQV 182 Query 165 EFADLLVLTHP------EPVAVAVLRRL---APRARITGGVDRVELALAHLDDNSRRGRT 215 EFAD +VL E AV+ RL APR + G +D +L LA + +RRGR Sbjct 183 EFADAVVLAGEAEDRWQEVRTEAVISRLTPTAPRGHLDG-LDPADL-LARVPAEARRGRI 240 Query 216 DTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRP 275 D PH PLL G P L ++ V +V F RRPFHPQRLH +D+LLDGVVRTRGR W+A++P Sbjct 241 DWPHGPLLRGQPSLESEAGVCVVLFEERRPFHPQRLHEVLDVLLDGVVRTRGRAWVASQP 300 Query 276 DQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLV 335 +WLESAGGGL V AG WLAA+ ++ V ER++ A L W +GDR + V+ Sbjct 301 GAALWLESAGGGLNVGHAGPWLAALDTAQWDEVSAERQVRASLNWDDYYGDRMQELVVIA 360 Query 336 CGADPTDIVNALNAALLSDDEMASPQR-WQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNS 394 ADP +I AL +ALL+D E+A + W Y DPFG+WH DPC +M G A ++ Sbjct 361 HEADPREITRALRSALLTDAEIAEGEAVWAGYEDPFGEWHTDPCPDMGAGTGSEPATGSA 420 Query 395 GESR 398 +R Sbjct 421 DAAR 424 >gi|296140971|ref|YP_003648214.1| cobalamin synthesis CobW domain-containing protein [Tsukamurella paurometabola DSM 20162] gi|296029105|gb|ADG79875.1| cobalamin synthesis CobW domain protein [Tsukamurella paurometabola DSM 20162] Length=405 Score = 270 bits (689), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 182/396 (46%), Positives = 229/396 (58%), Gaps = 27/396 (6%) Query 2 RTPVILVAGQDHTDEVTGALLRRTGTVVVEHRF----DGHVVRRMTATLSRGELITTEDA 57 RTPV+LV G + L GTVVV H G VVR + G Sbjct 7 RTPVLLVTGFGGQERALE--LAEPGTVVVHHDLSGLRQGMVVRSESTVRPDGVAEERVAL 64 Query 58 LEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGY 117 LE AHGCVSCT+R+DLL LLR LHRR V RIV+ L P LE + + AI+HV V + Sbjct 65 LELAHGCVSCTLREDLLPLLRALHRRAGVRRIVIRLDPTLEAEALIDAIEHVVVEMVGEV 124 Query 118 PDGPAALDVRVAAVVTCVDCVRWLPQSLGEDEL--------PDGRTVAQVTVGQAEFADL 169 P GPAA DV VA V+ +D WL +LGE++L D RTVAQ+ VG A ADL Sbjct 125 P-GPAARDVEVAGVIGFLDGATWLDDALGEEDLVERFAVVDGDERTVAQLAVGHAAHADL 183 Query 170 LVLT--HPEPVAV-AVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGL 226 LV+ P+P + AVLRRLAP A I ++ +A + +RR P PLL G Sbjct 184 LVVDGDSPDPARLRAVLRRLAPGAPIVRERAPLDRLVARI--GARRPAA-GPFDPLLLGC 240 Query 227 PPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGG 286 PPL DG+V IVEF+ARRP HP R H A+D+LLDGVV+ RGR+WLA RPD+ +WLESAG Sbjct 241 PPLEPDGDVRIVEFTARRPLHPGRFHEAIDVLLDGVVQARGRVWLATRPDEALWLESAGS 300 Query 287 GLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNA 346 GLRV AG+WLAA ER A W GDR + + VL+ GA+P ++ Sbjct 301 GLRVGPAGRWLAAGGEGTP-----ERWAMASAAWDDEHGDRASDIVVLLAGAEPDRVLEM 355 Query 347 LNAALLSDDEMASPQR-WQSYVDPFGDWHDDPCHEM 381 L A L++ E+A+ W ++ DPFGD H DPC ++ Sbjct 356 LRWAELTESELAAGSTVWAAWPDPFGDLHADPCEDL 391 >gi|262201432|ref|YP_003272640.1| cobalamin synthesis CobW domain-containing protein [Gordonia bronchialis DSM 43247] gi|262084779|gb|ACY20747.1| cobalamin synthesis CobW domain protein [Gordonia bronchialis DSM 43247] Length=442 Score = 251 bits (642), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 186/422 (45%), Positives = 235/422 (56%), Gaps = 48/422 (11%) Query 5 VILVAGQDHTDEV-TGALLRRTGTVVVEHRF----DGHVVRRMTATLSRGELITTEDALE 59 +ILVAG D + G GT ++ H G V R + + G + T++ + Sbjct 1 MILVAGLDRDAVIRVGESFVVAGTTLIHHDLRSVRSGAVTRTVVSVDPDGNELRTDELIR 60 Query 60 FAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPD 119 HGC SCT+R DLL LLRRLHRR V +IV+ L LEP+ + WAI+HV V GY D Sbjct 61 LEHGCASCTLRLDLLPLLRRLHRRRGVEQIVIALDCSLEPEALAWAIEHVIVADMPGYLD 120 Query 120 GPAALDVRVAAVVTCVDCVRWLPQSLGE--------------------------DELPDG 153 GPA LDV ++A VTCV + WL + G+ E+ D Sbjct 121 GPAGLDVAISATVTCVAEMDWLEAATGDVTLAESGELDKPDHGTSVPESEMIDDSEVDDD 180 Query 154 RTVAQVTVGQAEFADLLVLTHPEPVA---------VAVLRRLAPRARITGGVDR------ 198 RT+AQV VGQ FAD LV+ +P +AVL RLAP A I + + Sbjct 181 RTLAQVAVGQVAFADALVVAAADPALRDNWESARLMAVLTRLAPGAPIVMELPQRPVTAL 240 Query 199 -VELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDL 257 LA + +RRGR D PH LL G PPL + V IVEF+A RPFHP+RLH A+D+ Sbjct 241 HAARLLAAIGPGARRGRVDDPHGSLLRGEPPLTPECGVQIVEFTADRPFHPERLHDALDV 300 Query 258 LLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFAD 317 LLDGVV RGR+WLA R +++ WLESAGG LRV+ AG+WLAA +E+ VD ERR A Sbjct 301 LLDGVVCARGRVWLATRGEEMFWLESAGGALRVSIAGRWLAATPVAELDEVDTERRAMAA 360 Query 318 LMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMA-SPQRWQSYVDPFGDWHDD 376 L W GDRHT++ VLV ADP ++ L A L D EMA P W Y DPFG +H+D Sbjct 361 LRWDDVHGDRHTSIVVLVHRADPANVAEVLRRACLDDAEMADGPTGWAGYPDPFGVFHED 420 Query 377 PC 378 PC Sbjct 421 PC 422 >gi|325003292|ref|ZP_08124404.1| cobalamin synthesis CobW-like protein [Pseudonocardia sp. P1] Length=410 Score = 248 bits (633), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 160/334 (48%), Positives = 191/334 (58%), Gaps = 15/334 (4%) Query 58 LEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGY 117 LE AHGCVSCTIR+D+L L L V R+V+HL P LEP+P+CWA+ V G G Sbjct 59 LELAHGCVSCTIREDVLPTLAAL--TGTVDRVVLHLDPRLEPEPVCWALGAVLFEPGDGR 116 Query 118 PDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELP---------DGRTVAQVTVGQAEFAD 168 AA V + VV +D WL + G+ LP D RTVAQ+ VGQAEFAD Sbjct 117 AACTAADLVDLRGVVAVLDTDTWLDDATGDATLPERGLSTLPDDERTVAQLAVGQAEFAD 176 Query 169 LLVLTHPEPVA--VAVLRRLAPRA-RITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAG 225 ++V AVL RLAP A R+T L L ++RRG H PLL G Sbjct 177 VVVTAGGPATGRTAAVLDRLAPTAPRLTADTADHRLFCDGLAPDARRGVPGGVHDPLLRG 236 Query 226 LPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAG 285 PPL G V + FS RRPFHP RLH A+D LLDGVVRTRGR+WLA RPD V+WLESAG Sbjct 237 TPPLEESGGVRTLLFSERRPFHPDRLHDAIDSLLDGVVRTRGRVWLATRPDAVLWLESAG 296 Query 286 GGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVN 345 GGLR+ AG WL A +RR A L W +GDR + VL ADP D+ Sbjct 297 GGLRIGHAGDWLDGADEQAWAEAGDQRRAMAALSWHPRWGDRAQDLVVLCHEADPDDVDA 356 Query 346 ALNAALLSDDEMASPQ-RWQSYVDPFGDWHDDPC 378 AL ALL+D E+A+ + W DPFG HD+PC Sbjct 357 ALRLALLTDAEIAAGEAAWAELPDPFGWAHDEPC 390 >gi|331696033|ref|YP_004332272.1| cobalamin synthesis CobW domain-containing protein [Pseudonocardia dioxanivorans CB1190] gi|326950722|gb|AEA24419.1| cobalamin synthesis CobW domain protein [Pseudonocardia dioxanivorans CB1190] Length=450 Score = 244 bits (624), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 177/413 (43%), Positives = 231/413 (56%), Gaps = 45/413 (10%) Query 3 TPVILVAG--QDHTDEVTGALLRRTGTVVVEHRF----DGHVVRRMTATLSRGELITTED 56 T ++++AG D T+++ +L GTVVV H DG V RR+ R T Sbjct 15 TELVVLAGLTPDGTEQIAQLMLAEPGTVVVHHDLRHLGDGRVFRRI-----RDATSDTAT 69 Query 57 ALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHG 116 +E AHGC+SCT+RDDLL R + R+VVHL P LEP+ +C+A+ H+ + Sbjct 70 EVELAHGCLSCTLRDDLLP--RVVELTGQARRVVVHLDPVLEPEQVCFALAHLLLG---- 123 Query 117 YPDGPAALDVR----VAAVVTCVDCVRWLPQSLGEDELP---------DGRTVAQVTVGQ 163 D PAA V + V+T +D W + GE+ + D RT+AQ+ Q Sbjct 124 --DEPAATTVTDVVDLLGVITVIDVATWFDDATGEETVAERGLVELFDDERTIAQLATAQ 181 Query 164 AEFADLLVLTHPEPV-----AVAVLRRLAPRA---RIT-GGVDRVELALAHLDDNSRRGR 214 EFADL+V P AVL RL+P A R+ +D L+LA + +RRGR Sbjct 182 VEFADLIVRCGTAPARELARTNAVLARLSPTAGQVRLADAALDPAVLSLAVVAPEARRGR 241 Query 215 TDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANR 274 D H PLL G PPL +D V++ FS RRPFHPQRLH AVDLLLDGVVR+RGR+WLA R Sbjct 242 PDGVHAPLLRGAPPLDSDCGVSLFAFSDRRPFHPQRLHDAVDLLLDGVVRSRGRVWLATR 301 Query 275 PDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVL 334 P +V+WLESAGGGLR+ AG WLA + ER A L W +GDR +TVL Sbjct 302 PAEVLWLESAGGGLRLGRAGHWLADAGEEAWEHATPERAAMASLGWDEHYGDRSQDITVL 361 Query 335 VCGADPTDIVNALNAALLSDDEMASPQR-WQSYVDPFGDWHDDPCHEMPDAAG 386 AD ++ AL+AALL+DDE+A+ +R W DPFG W + H DA G Sbjct 362 TYAADHAEMSAALHAALLTDDELAAGERAWAQLPDPFGSWQE---HGTGDADG 411 >gi|302527618|ref|ZP_07279960.1| predicted protein [Streptomyces sp. AA4] gi|302436513|gb|EFL08329.1| predicted protein [Streptomyces sp. AA4] Length=413 Score = 232 bits (591), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 182/416 (44%), Positives = 233/416 (57%), Gaps = 29/416 (6%) Query 2 RTPVILVAGQDHTDEVTGALLRRT-GTVVVEH--RFDGHVVRRMTATLSRGELITTEDAL 58 R P++L +G TD + LLR + GT VV H R G V R L + +T L Sbjct 6 RVPLVLCSGIARTDALAALLLRASPGTAVVHHDLRDIGSGVVRRRIRLRGRDELTP---L 62 Query 59 EFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYP 118 E AHGCV+CT+R+DLL LLRRL R V RIVV L +EP+P+ WAI +V V Sbjct 63 ELAHGCVNCTLREDLLPLLRRLARMPQVDRIVVRLDEAMEPEPVSWAIRNVLVG------ 116 Query 119 DGPAALDVRVAAVVTCVDCVRWLPQSLGEDEL---------PDGRTVAQVTVGQAEFADL 169 D P + DV + AV T +DC WL G+D L D RTVAQV + Q E AD+ Sbjct 117 DRPVSDDVELEAVFTVLDCATWLADVTGDDLLAERGLQGSPEDERTVAQVALSQVESADV 176 Query 170 LVLTHPEPVAVAVLRRLAPRARITGGVDRVELA-------LAHLDDNSRRGRTDTPHTPL 222 LVL A + + A R+ V RVELA A + ++RRG H L Sbjct 177 LVLAGAAQDAWSAAKSSAVLDRVAPSVPRVELARTDAAGLFAAIPADARRGEVTDLHGAL 236 Query 223 LAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLE 282 L G PPL D + ++ F+A+RPFHP+RLH A+DLLLDGVVRTRGR W+A++PD W+E Sbjct 237 LRGAPPLHPDCGIELLRFTAQRPFHPERLHEAIDLLLDGVVRTRGRAWVASQPDVAFWIE 296 Query 283 SAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTD 342 SAGGGL + AG WLA+ + A V ERR A L W GDR + V+ A P + Sbjct 297 SAGGGLGIGHAGPWLASPDGPDWADVSPERRTLASLRWDPVHGDRAQELVVVADQAAPAE 356 Query 343 IVNALNAALLSDDEMASPQ-RWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGES 397 I AL AALL+D E+A + W+ Y DPFG+WH+DPC E + SA E+ Sbjct 357 IEAALQAALLTDAELAEGEAAWREYPDPFGNWHEDPCEETEEPDRHASAANQKDET 412 >gi|326383109|ref|ZP_08204798.1| cobalamin synthesis CobW domain-containing protein [Gordonia neofelifaecis NRRL B-59395] gi|326198245|gb|EGD55430.1| cobalamin synthesis CobW domain-containing protein [Gordonia neofelifaecis NRRL B-59395] Length=429 Score = 195 bits (495), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 170/426 (40%), Positives = 215/426 (51%), Gaps = 33/426 (7%) Query 2 RTPVILVAGQDHTDEVTGA-LLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTE----D 56 RTP+ LV G D T A L GT +V H R+T ++ R +L + D Sbjct 8 RTPLTLVTGLDRTVSARIAHALAAPGTAIVSHDLRDVGRGRVTRSVHRIDLDGHDRFSLD 67 Query 57 ALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHG 116 +E HGCVSCT+R DLL LLR LHR V RIVV L P +EP+ + + V V G Sbjct 68 DVELEHGCVSCTLRLDLLPLLRVLHREPGVARIVVALDPVVEPENVALEVRQTVVDV-PG 126 Query 117 YPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDEL--------PDGRTVAQVTVGQAEFAD 168 A DV + V VD RWL ++ G+ L D RTVAQV VGQ FAD Sbjct 127 LAPAAAGDDVSLTHTVCGVDAGRWLDEATGDITLAEAGLSVDEDERTVAQVAVGQVRFAD 186 Query 169 LLVLTHPEPVAVA--------VLRRLAPRA--RITGGVDRVELAL--AHLDDNSRR---G 213 +++ + A VL RLAP A R + R++ AL L +R G Sbjct 187 TVIVERADSTGGAWNLARLHAVLVRLAPGAGMRTLNSLQRLDTALMAGALGSGTRHSPHG 246 Query 214 RTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLAN 273 P PLLAG P L D V ++ A RPFHP+RLH A+D LLDGVV +GRLW+A Sbjct 247 VPRRPFDPLLAGRPDLDGDCGVELITVEAARPFHPERLHLALDALLDGVVTAQGRLWIAA 306 Query 274 RPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTV 333 PD V+WLESAGG L + G+WL AAS D E R A L W +GDRH+++TV Sbjct 307 NPDDVLWLESAGGALGIRRVGRWL---AASPEGTADPEHRAMAALHWDDVYGDRHSSVTV 363 Query 334 LVCGADPTDIVNALNAALLSDDEMA-SPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHR 392 L A P I A + AL++D E+A P + PFG H DPC + + Sbjct 364 LCHRAAPDQIRAAFDDALVTDAELALGPDFLANLPSPFGTEHRDPCDDFESTDRSVQVDQ 423 Query 393 NSGESR 398 GE R Sbjct 424 TEGEDR 429 >gi|256378449|ref|YP_003102109.1| cobalamin synthesis CobW domain-containing protein [Actinosynnema mirum DSM 43827] gi|255922752|gb|ACU38263.1| cobalamin synthesis CobW domain protein [Actinosynnema mirum DSM 43827] Length=363 Score = 187 bits (476), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 154/352 (44%), Positives = 195/352 (56%), Gaps = 35/352 (9%) Query 37 HVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPW 96 H +R + + R + LE AHGCVSCT+R DLL LL L GR+VVHL P Sbjct 25 HDLRELAQGIVRRWVDGELTVLELAHGCVSCTLRLDLLPLLESLG-----GRVVVHLDPA 79 Query 97 LEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPD---- 152 LEP+ +C+A+ V V V A WL + GED++ D Sbjct 80 LEPEAVCFALREVDVRVDAVVSVVDRAT---------------WLADATGEDDMADRGLA 124 Query 153 -----GRTVAQVTVGQAEFADLLVLT--HPEPVAVAVLRRLAPRA-RITGGVDRVELALA 204 RTVAQV VGQAEFAD LVL P+PV AVL RL PRA R LA Sbjct 125 AADGDDRTVAQVVVGQAEFADALVLVGDDPDPVLDAVLDRLNPRAPRRDRRGLDAAALLA 184 Query 205 HLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVR 264 + ++RRGR D LL G PPL VA+V F+ARRPFHP RLH A+D+LLDGVVR Sbjct 185 AVPADARRGRFDDGFGALLRGQPPLEPAHGVAVVHFTARRPFHPVRLHDALDVLLDGVVR 244 Query 265 TRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPF 324 TRGR+WL ++P+ +WLESAGGGL V + G WLAA+ + + ERRL A W F Sbjct 245 TRGRVWLVSQPETALWLESAGGGLNVGNLGHWLAAV--DDWSDEPAERRLAAAAHWDPEF 302 Query 325 GDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDD 376 GDR + V+ A P +I L AL++D+E+A + + DPF +W D+ Sbjct 303 GDRAQELVVITGSASPDEIAAVLRDALVTDEELALADELE-FADPFAEWRDE 353 >gi|238063059|ref|ZP_04607768.1| cobalamin synthesis protein cobW [Micromonospora sp. ATCC 39149] gi|237884870|gb|EEP73698.1| cobalamin synthesis protein cobW [Micromonospora sp. ATCC 39149] Length=431 Score = 153 bits (386), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 119/345 (35%), Positives = 173/345 (51%), Gaps = 33/345 (9%) Query 52 ITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRV 111 I ++ +E HGCVSCT+R+D+L L RL R +V+ L +EP+ + A + + Sbjct 72 IIEDEQVELRHGCVSCTLREDVLPTLVRLTRSHPGQDLVLMLPEVVEPEAVAAACAYCLI 131 Query 112 CVGHGYPDGPAALDV-RVAAVVTCVDCVRWLPQSLGEDELP---------DGRTVAQVTV 161 DG D+ RV + VT +D L D+L D R +A V V Sbjct 132 -------DGAPITDLLRVDSYVTVLDAEHLLDGLASTDDLTALGIQAAEDDHRALADVVV 184 Query 162 GQAEFADLLVL-------THPEPVAVAVLRRLAP-RARITGGVDRVELA-LAHLDDNSRR 212 Q E+AD L+L +L+R+AP A I DRV+ + L ++RR Sbjct 185 RQIEYADTLLLWGQSREGDFDTSRMAILLQRMAPWAAHIRVDDDRVDASTLTRQLRHTRR 244 Query 213 GRTDTPH------TPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTR 266 R +TP G+ D V F ARRPFHPQRLH ++ + ++R+R Sbjct 245 HRPETPGILTRGLQGYTLGIHEPEPDCGVVSTVFRARRPFHPQRLHDVLEDVNAEIIRSR 304 Query 267 GRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGD 326 G LWLA++PD V+ E AGGGL + S G WLAA+ +V+ +RRL A L W +GD Sbjct 305 GHLWLASQPDTVVAWEFAGGGLAMGSLGHWLAALPEDRWEHVEDQRRLAAALDWDPYYGD 364 Query 327 RHTAMTVLVCGADPTDIVNALNAALLSDDEMA-SPQRWQSYVDPF 370 RH + + DP ++ + L LL+D E+A + W++Y DPF Sbjct 365 RHQHLVFIGLDIDPAELHHTLTGCLLTDAELADGEETWRTYHDPF 409 >gi|157145192|ref|YP_001452511.1| hypothetical protein CKO_00925 [Citrobacter koseri ATCC BAA-895] gi|157082397|gb|ABV12075.1| hypothetical protein CKO_00925 [Citrobacter koseri ATCC BAA-895] gi|204636642|gb|ACI01736.1| putative cobalamin synthesis protein/P47K [Escherichia coli] Length=407 Score = 144 bits (363), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 114/379 (31%), Positives = 170/379 (45%), Gaps = 37/379 (9%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLL+ + R Sbjct 41 RRVAVIVNDMSEVNIDAALVREGGAELSR----TDEKLVEMSNGCICCTLREDLLLEVNR 96 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCV 138 L + ++V+ EP P+ DG + V R+ +VT VD Sbjct 97 LAKEGRFDQLVIESTGISEPLPVAETFTFAG-------DDGESLSTVARLDTMVTVVDAY 149 Query 139 RWLPQSLGEDELP---------DGRTVAQVTVGQAEFADLLVLTHPEPVA-------VAV 182 +L ED + D R+V + + Q EF D+LVL + ++ +A+ Sbjct 150 NFLKDYGSEDSIQSRGESLGEGDERSVVDLLIDQIEFCDVLVLNKVDLISEAQKEKLMAI 209 Query 183 LRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIV 238 LR L PRARI G V + L D + + L P + + Sbjct 210 LRSLNPRARIVVSQFGQVPLGNILNTGLFDFEQAAQAPGWLKELRGEHTPETEEYGITSF 269 Query 239 EFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLA 298 F ARRPFHP R ++ LDGVVR++G WLA+RP+ AGG R G W A Sbjct 270 VFRARRPFHPTRFWQVMENELDGVVRSKGYFWLASRPEFAGSWSQAGGIARQGLGGMWWA 329 Query 299 AMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMA 358 ++ D E F W+ GD + + + +++ N L++ALL+D EMA Sbjct 330 SVPKGRWPE-DAESLKFIMSNWIDGIGDARQELVFIGMDMNESELRNRLDSALLTDAEMA 388 Query 359 S-PQRWQSYVDPFGDWHDD 376 PQ+W+ Y DP W ++ Sbjct 389 EGPQKWRHYSDPVEPWFEE 407 >gi|284919703|emb|CAX65480.1| hypothetical protein [Enterobacter hormaechei] Length=413 Score = 144 bits (363), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 114/379 (31%), Positives = 170/379 (45%), Gaps = 37/379 (9%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLL+ + R Sbjct 47 RRVAVIVNDMSEVNIDAALVREGGAELSR----TDEKLVEMSNGCICCTLREDLLLEVNR 102 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCV 138 L + ++V+ EP P+ DG + V R+ +VT VD Sbjct 103 LAKEGRFDQLVIESTGISEPLPVAETFTFAG-------DDGESLSTVARLDTMVTVVDAY 155 Query 139 RWLPQSLGEDELP---------DGRTVAQVTVGQAEFADLLVLTHPEPVA-------VAV 182 +L ED + D R+V + + Q EF D+LVL + ++ +A+ Sbjct 156 NFLKDYGSEDSIQSRGESLGEGDERSVVDLLIDQIEFCDVLVLNKVDLISEAQKEKLMAI 215 Query 183 LRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIV 238 LR L PRARI G V + L D + + L P + + Sbjct 216 LRSLNPRARIVVSQFGQVPLGNILNTGLFDFEQAAQAPGWLKELRGEHTPETEEYGITSF 275 Query 239 EFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLA 298 F ARRPFHP R ++ LDGVVR++G WLA+RP+ AGG R G W A Sbjct 276 VFRARRPFHPTRFWQVMENELDGVVRSKGYFWLASRPEFAGSWSQAGGIARQGLGGMWWA 335 Query 299 AMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMA 358 ++ D E F W+ GD + + + +++ N L++ALL+D EMA Sbjct 336 SVPKGRWPE-DAESLKFIMSNWIDGIGDARQELVFIGMDMNESELRNRLDSALLTDAEMA 394 Query 359 S-PQRWQSYVDPFGDWHDD 376 PQ+W+ Y DP W ++ Sbjct 395 EGPQKWRHYSDPVEPWFEE 413 >gi|38639671|ref|NP_943440.1| CobW [Klebsiella pneumoniae] gi|168998627|ref|YP_001687895.1| hypothetical protein pK2044_00325 [Klebsiella pneumoniae NTUH-K2044] gi|38016769|gb|AAR07790.1| CobW [Klebsiella pneumoniae] gi|238549644|dbj|BAH65995.1| cobalamin synthesis related protein [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Length=406 Score = 139 bits (349), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 116/378 (31%), Positives = 168/378 (45%), Gaps = 37/378 (9%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLL+ + R Sbjct 41 RRVAVIVNDMSEVNIDAALVRDGGAELSR----TDEKLVEMSNGCICCTLREDLLLEVNR 96 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCV 138 L + ++V+ EP P+ DG + V R+ +VT VD Sbjct 97 LAKEGRFDQLVIESTGISEPLPVA-------ETFTFAGDDGESLSTVARLDTMVTVVDAF 149 Query 139 RWLPQSLGEDELP---------DGRTVAQVTVGQAEFADLLVLTHPEPVA-------VAV 182 +L ED + D R+V + + Q EF D+LVL + ++ +AV Sbjct 150 NFLKDYGSEDSIQSRGESLGDGDERSVVDLLIDQIEFCDVLVLNKVDLISEAQKDKLMAV 209 Query 183 LRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIV 238 LR L PRARI G V + L D + + L P + + Sbjct 210 LRSLNPRARIVVSQFGKVPLDNVLNTGLFDFDQAAQAPGWLKELRGEHTPETEEYGITSF 269 Query 239 EFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLA 298 F ARRPFHP R +D L+GVVR++G WLA+RP+ AGG R G W A Sbjct 270 VFRARRPFHPARFWQVMDNELNGVVRSKGYFWLASRPEFAGSWSQAGGVARQGLGGMWWA 329 Query 299 AMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMA 358 ++ E D E F W+ GD + + + +++ N L +ALL+D EMA Sbjct 330 SV-PKERWPEDPESLKFIMSHWMDGIGDARQELVFIGMEMNESELRNRLESALLTDTEMA 388 Query 359 S-PQRWQSYVDPFGDWHD 375 P +W+ Y DP W D Sbjct 389 EGPLKWRHYPDPVEPWFD 406 >gi|339764734|gb|AEK00954.1| CobW [Klebsiella pneumoniae KCTC 2242] Length=406 Score = 138 bits (347), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 116/378 (31%), Positives = 168/378 (45%), Gaps = 37/378 (9%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLL+ + R Sbjct 41 RRVAVIVNDMSEVNIDAALVRDGGAELSR----TDEKLVEMSNGCICCTLREDLLLEVNR 96 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCV 138 L + ++V+ EP P+ DG + V R+ +VT VD Sbjct 97 LAKEGRFDQLVIESTGISEPLPVA-------ETFTFAGDDGESLSTVARLDTMVTVVDAF 149 Query 139 RWLPQSLGEDELP---------DGRTVAQVTVGQAEFADLLVLTHPEPVA-------VAV 182 +L ED + D R+V + + Q EF D+LVL + ++ +AV Sbjct 150 NFLKDYGSEDSIQSRGESLGDGDERSVVDLLIDQIEFCDVLVLNKVDLISEAQKDKLMAV 209 Query 183 LRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIV 238 LR L PRARI G V + L D + + L P + + Sbjct 210 LRSLNPRARIVVSQFGKVPLDNVLNTGLFDFDQAAQAPGWLKELRGEHTPETEEYGITSF 269 Query 239 EFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLA 298 F ARRPFHP R +D L+GVVR++G WLA+RP+ AGG R G W A Sbjct 270 VFRARRPFHPARFWQVMDNELNGVVRSKGYFWLASRPEFAGSWSQAGGVARQGLRGMWWA 329 Query 299 AMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMA 358 ++ E D E F W+ GD + + + +++ N L +ALL+D EMA Sbjct 330 SV-PKERWPEDPESLKFIMSHWMDGIGDARQELVFIGMEMNESELRNRLESALLTDTEMA 388 Query 359 S-PQRWQSYVDPFGDWHD 375 P +W+ Y DP W D Sbjct 389 EGPLKWRHYPDPVEPWFD 406 >gi|257095797|ref|YP_003169438.1| cobalamin synthesis protein P47K [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gi|257048321|gb|ACV37509.1| cobalamin synthesis protein P47K [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length=410 Score = 136 bits (343), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 114/380 (30%), Positives = 166/380 (44%), Gaps = 50/380 (13%) Query 31 EHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIV 90 E D +V A LSR E E +E ++GC+ CT+R+DLL+ + RL + + ++ Sbjct 50 EVNIDARLVAEGGARLSRAE----EKMVEMSNGCICCTLREDLLIEIARLAKEERFDYLL 105 Query 91 VHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCVRWLP------- 142 + EP P+ DG + D+ R+ +VT VD +L Sbjct 106 IESTGISEPLPVAETFTFRD-------EDGTSLSDISRLDTMVTVVDGFNFLNDYSSQDY 158 Query 143 -----QSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAV-------AVLRRLAPRA 190 +SLGE D RTV + V Q EF D++VL + + A+LR L PRA Sbjct 159 IADRGESLGEG---DERTVVNLLVEQVEFCDVIVLNKIDLLPAEDLARLEAILRTLNPRA 215 Query 191 RITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAG---------LPPLAADGEVAIVEFS 241 I L+ GR D G +P A G + V + Sbjct 216 DIVQAC----FGQMPLERILNTGRFDFERAAQAPGWLQELRGEHIPETAEYGISSFV-YR 270 Query 242 ARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMA 301 ARRPFHP R H ++ GV+R++G WLA RP V AG R G W A+ Sbjct 271 ARRPFHPARFHEWINQEWPGVIRSKGYFWLATRPGLVGSWSQAGPVTRHEVGGLWWVAVP 330 Query 302 ASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEM-ASP 360 ++ + RR+ D W+ P+GD + ++ D + + +A +A LLSD E+ A P Sbjct 331 ETDWPQDEEGRRIILD-RWLEPYGDAQQELVMIGIEMDESALRHAFDACLLSDTELVAGP 389 Query 361 QRWQSYVDPFGDWHDDPCHE 380 + W Y DPF W D E Sbjct 390 EAWVRYEDPFPQWSVDEVEE 409 >gi|313200673|ref|YP_004039331.1| cobalamin synthesis protein p47k [Methylovorus sp. MP688] gi|312439989|gb|ADQ84095.1| cobalamin synthesis protein P47K [Methylovorus sp. MP688] Length=405 Score = 136 bits (342), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 119/383 (32%), Positives = 171/383 (45%), Gaps = 49/383 (12%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D H+VR A LSR E E +E ++GC+ CT+R+DLLV +RR Sbjct 31 RRVAVIVNDMSEVNIDAHLVREGGAALSRAE----EKLVEMSNGCICCTLREDLLVEIRR 86 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVR 139 L D +++ EP P+ D + R+ +VT VD Sbjct 87 LAAEDRFDYLLIESTGISEPLPVA------ETFTFRDENDVSLSDVSRLDTMVTVVDGYH 140 Query 140 WL------------PQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVA------ 181 +L +++GE+ D RTV + V Q EF D++VL + + A Sbjct 141 FLRDYSSRDFLADRGETMGEE---DTRTVVDLLVEQVEFCDVIVLNKTDLMTPAEIGQLE 197 Query 182 -VLRRLAPRARITGG------VDRVELALAHLDDNSRRGRTDTPH--TPLLAGLPPLAAD 232 +L+ L PRA I +DRV L D + + D P L P + Sbjct 198 GILKTLNPRADIVHSSFGKVPLDRV-LNTGRFDFEAAQ---DAPGWLKELRGEHVPETEE 253 Query 233 GEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVAS 292 ++ + AR+PFHP+RL A + GVVR++G WLA+RPD AG R Sbjct 254 YGISSFVYRARKPFHPERLWAWLGQEWPGVVRSKGHFWLASRPDFCANWSQAGAISRNEL 313 Query 293 AGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALL 352 AG W AA S+ D E W+ P+GDR + ++ + + I +A LL Sbjct 314 AGMWWAA-TPSDYWPQDEESLAMIKQRWLEPWGDRQQELVLIGMNMNESAIRAGFDACLL 372 Query 353 SDDEMASP-QRWQSYVDPFGDWH 374 SD+EMAS W+ DPF WH Sbjct 373 SDEEMASGVSDWRKLPDPFPAWH 395 >gi|291300850|ref|YP_003512128.1| cobalamin synthesis CobW domain-containing protein [Stackebrandtia nassauensis DSM 44728] gi|290570070|gb|ADD43035.1| cobalamin synthesis CobW domain protein [Stackebrandtia nassauensis DSM 44728] Length=408 Score = 135 bits (339), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 132/379 (35%), Positives = 189/379 (50%), Gaps = 45/379 (11%) Query 28 VVVEH---RFDGHVVRRMTATLSRGELITTEDA-LEFAHGCVSCTIRDDLLVLLRRLHRR 83 +VV H R + +VRR+ T + T EDA + HGC++CT+RDD+L L RL Sbjct 47 LVVSHDVSRLESGIVRRLVTTATD----TIEDATVHLDHGCLACTVRDDVLPTLARLADN 102 Query 84 DNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDG-PAALDVRVAAVVTCVDCVRWLP 142 I + + LEP + A + + DG P VR+ +VV +D +L Sbjct 103 HPGRDIALVIPSTLEPSALAAACAYCHI-------DGRPVTELVRLDSVVAVIDAATFLD 155 Query 143 QSLGEDELP---------DGRTVAQVTVGQAEFADLLVLTHP----EPVAVAVL-RRLAP 188 +D+L D RTVA V Q E+AD +++T E ++VL RRLAP Sbjct 156 DLRSDDDLSHRGLAAADNDLRTVADVAARQVEYADTVLITGGDGDFETTRLSVLTRRLAP 215 Query 189 RARITGGVDRVELALAHLDDNSRRGRTDTPHTPL--LAGLP----PLAADGEVAIVEFSA 242 A V +A ++RR DTP L G P + D V+ + F++ Sbjct 216 WA--------VHVADTANLRDTRRFDADTPEVFARGLEGYPIGVHDPSPDCGVSSLVFAS 267 Query 243 RRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAA 302 RRPFHP RLHA + + D +R RG LWLA++PD + ESAGGGL + S G WLA++ Sbjct 268 RRPFHPGRLHALLGTIADHTLRGRGHLWLASQPDHAVAWESAGGGLSMGSLGHWLASLPD 327 Query 303 SEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMAS-PQ 361 + V RRL ADL W +GDR + + D D+ AL LL+D E+++ + Sbjct 328 EDRDDVSPRRRLTADLEWDPYYGDRGIKLDFVGLDFDAVDLQRALTTCLLTDAELSTGEE 387 Query 362 RWQSYVDPFGDWHDDPCHE 380 W+++ DPF DDP E Sbjct 388 TWRTWHDPFAGCLDDPTDE 406 >gi|302868522|ref|YP_003837159.1| cobalamin synthesis CobW domain-containing protein [Micromonospora aurantiaca ATCC 27029] gi|302571381|gb|ADL47583.1| cobalamin synthesis CobW domain protein [Micromonospora aurantiaca ATCC 27029] Length=433 Score = 134 bits (338), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 125/363 (35%), Positives = 177/363 (49%), Gaps = 42/363 (11%) Query 38 VVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWL 97 VVRR+ + G + ++ + HGC SCT+R+D+L L RL R +V+ L + Sbjct 61 VVRRV---IRSGTGVIEDEQVALRHGCASCTLREDVLPTLARLTRSHPGRDLVLMLPEVV 117 Query 98 EPQPICWAIDHVRVCVGHGYPDGPAALD-VRVAAVVTCVDCVRWLPQSLGEDELP----- 151 EP+ + A H V DG D +RV + VT +D L D+L Sbjct 118 EPEAVAAACAHCLV-------DGAPITDLIRVDSYVTVLDAEHLLDGLATTDDLSTLGIQ 170 Query 152 ----DGRTVAQVTVGQAEFADLLVL-------THPEPVAVAVLRRLAPRA---RITGG-V 196 D R +A V V Q E+AD LVL +L+R+AP A R+ G + Sbjct 171 AADDDHRALADVVVRQIEYADTLVLWGQSRGGEFDTGRLAVLLQRIAPWATHLRVDGDLI 230 Query 197 DRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLA-------ADGEVAIVEFSARRPFHPQ 249 D V AL ++ R R +TP L GL D V F ARRPFHPQ Sbjct 231 DAV--ALTRQLRHTHRHRPETPGV-LARGLQGYTLGAHEPEPDCGVVSAAFRARRPFHPQ 287 Query 250 RLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVD 309 RLH ++ + V+R+RG LWLA++PD V+ E AGGGL + S G WL ++ +V+ Sbjct 288 RLHDVLEEVNAEVIRSRGHLWLASQPDTVIAWEFAGGGLSMGSLGHWLVSLPEDRWEHVE 347 Query 310 LERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQ-RWQSYVD 368 +RRL A L W +GDRH + + DP ++ L LL+D E+A + W++Y D Sbjct 348 DQRRLAAALDWDPYYGDRHQHLVFIGLDVDPVELHRTLAGCLLTDAELADGEDTWRTYTD 407 Query 369 PFG 371 PF Sbjct 408 PFA 410 >gi|317053880|ref|YP_004117905.1| cobalamin synthesis protein P47K [Pantoea sp. At-9b] gi|316951875|gb|ADU71349.1| cobalamin synthesis protein P47K [Pantoea sp. At-9b] Length=407 Score = 134 bits (336), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 117/381 (31%), Positives = 166/381 (44%), Gaps = 43/381 (11%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLL+ +RR Sbjct 36 RRVAVIVNDMSEVNIDAALVRNGGAELSR----TDEKLVEMSNGCICCTLREDLLLEVRR 91 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPA-ALDVRVAAVVTCVDCV 138 L ++V+ EP P+ DG + + R+ +VT VD Sbjct 92 LAEAGRFDQLVIESTGISEPLPVA-------ETFTFADEDGQSLSRFARLDTMVTVVDGY 144 Query 139 RWL------------PQSLGEDELPDGRTVAQVTVGQAEFADLLVLT-------HPEPVA 179 +L +SLGE D R+V + V Q EF D+LV+ H + Sbjct 145 NFLRDYRSTDSLQARGESLGE---ADARSVVDLLVDQIEFCDVLVVNKTDLISEHDQQTL 201 Query 180 VAVLRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEV 235 A+LR L PRA+I G V EL D + L P + + Sbjct 202 HAMLRSLNPRAQIVFSRFGQVPLTELLETGRFDFDAAAQAPGWLQELRGEHQPETEEYGI 261 Query 236 AIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGK 295 + ARRPFHPQR AV+ L+GV+R++G WLA+RP+ AG R AG Sbjct 262 RSFVYRARRPFHPQRFWHAVNHQLEGVIRSKGYFWLASRPEYAAMWSQAGAVARQGYAGH 321 Query 296 WLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDD 355 W A++ E D E F W GD + + D + NAL+ ALL+ Sbjct 322 WWASI-PRERWPQDEESLAFIARHWQEGIGDARQELVFIGIEMDEDQVRNALDHALLTSA 380 Query 356 EMAS-PQRWQSYVDPFGDWHD 375 EMA+ P W+ DP +W + Sbjct 381 EMAAGPAHWKQLSDPLPEWFE 401 >gi|323519849|gb|ADX94230.1| CobW/P47K family protein [Acinetobacter baumannii TCDC-AB0715] gi|333365412|gb|EGK47426.1| G3E family GTPase [Acinetobacter baumannii AB210] Length=421 Score = 134 bits (336), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 114/380 (30%), Positives = 170/380 (45%), Gaps = 51/380 (13%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLLV +RR Sbjct 51 RRIAVIVNDMSEVNIDAALVREGGAELSR----TDEKLVEMSNGCICCTLREDLLVEVRR 106 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCV 138 L ++V+ EP P+ DG + + R+ +VT VD Sbjct 107 LADEGRFDQLVIESTGISEPLPVA-------ETFTFEDEDGNSLNEFARLDTMVTVVDAF 159 Query 139 RWLP------------QSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPV-------A 179 +L +SLGE D RTV + + Q EF D++VL + + Sbjct 160 NFLKDYSSVDSLQQRGESLGE---QDERTVVDLLIDQIEFCDVIVLNKIDLIDQAQQDQL 216 Query 180 VAVLRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEV 235 +A+L+ L PRARI G V ++ L D + L P + + Sbjct 217 IAILKTLNPRARIEIAQFGKVALDKILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGI 276 Query 236 AIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGK 295 + + ARRPFHP+R + V GVVR++G WLA P AG R AG Sbjct 277 SSFVYRARRPFHPERFYDLVQAEWPGVVRSKGFFWLATEPTLAYSWSQAGAMARHGLAGY 336 Query 296 WLAAMAA----SEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAAL 351 W AA+A S++A ++ ++ W GD + ++ D ++ L++ L Sbjct 337 WWAAVAEEDWPSDLASIEQIKK-----NWDARTGDARQELVLIGMQMDEQALIQRLDSCL 391 Query 352 LSDDEMA-SPQRWQSYVDPF 370 LSD+EMA PQ WQS+ +PF Sbjct 392 LSDEEMALGPQVWQSWSNPF 411 >gi|342225721|gb|EGT90707.1| CobW/HypB/UreG, nucleotide-binding domain protein [Acinetobacter baumannii ABNIH1] Length=409 Score = 133 bits (334), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 114/380 (30%), Positives = 170/380 (45%), Gaps = 51/380 (13%) Query 23 RRTGTVV---VEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRR 79 RR +V E D +VR A LSR T E +E ++GC+ CT+R+DLLV +RR Sbjct 39 RRIAVIVNDMSEVNIDAALVREGGAELSR----TDEKLVEMSNGCICCTLREDLLVEVRR 94 Query 80 LHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDV-RVAAVVTCVDCV 138 L ++V+ EP P+ DG + + R+ +VT VD Sbjct 95 LANEGRFDQLVIESTGISEPLPVA-------ETFTFEDEDGNSLNEFARLDTMVTVVDAF 147 Query 139 RWLP------------QSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPV-------A 179 +L +SLGE D RTV + + Q EF D++VL + + Sbjct 148 NFLKDYSSVDSLQQRGESLGE---QDERTVVDLLIDQIEFCDVIVLNKIDLIDRAQQDQL 204 Query 180 VAVLRRLAPRARIT----GGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEV 235 +A+L+ L PRARI G V ++ L D + L P + + Sbjct 205 IAILKTLNPRARIEIAQFGKVALDKILNTQLFDFDEAAQAPGWLKELRGEHTPETEEYGI 264 Query 236 AIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGK 295 + + ARRPFHP+R + V GVVR++G WLA P AG R AG Sbjct 265 SSFVYRARRPFHPERFYDLVQAEWPGVVRSKGFFWLAAEPTLAYSWSQAGAMARHGLAGY 324 Query 296 WLAAMAA----SEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAAL 351 W AA+A S++A ++ ++ W GD + ++ D ++ L++ L Sbjct 325 WWAAVAEEDWPSDLASIEEIKK-----NWDARTGDARQELVLIGMQMDEQALIQRLDSCL 379 Query 352 LSDDEMA-SPQRWQSYVDPF 370 LSD+EMA PQ WQS+ +PF Sbjct 380 LSDEEMALGPQVWQSWSNPF 399 Lambda K H 0.323 0.138 0.437 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 782660155392 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40