BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0122 Length=122 Score E Sequences producing significant alignments: (Bits) Value gi|15607264|ref|NP_214636.1| hypothetical protein Rv0122 [Mycoba... 248 1e-64 gi|167966876|ref|ZP_02549153.1| hypothetical protein MtubH3_0195... 184 5e-45 gi|308378551|ref|ZP_07482970.2| hypothetical protein TMIG_00407 ... 151 3e-35 gi|254549057|ref|ZP_05139504.1| hypothetical protein Mtube_01096... 125 2e-27 gi|227548715|ref|ZP_03978764.1| conserved hypothetical protein [... 37.7 0.51 gi|340793304|ref|YP_004758767.1| hypothetical protein CVAR_0346 ... 37.4 0.77 gi|334338334|ref|YP_004543486.1| hypothetical protein Isova_2907... 36.6 1.3 gi|288923011|ref|ZP_06417166.1| hypothetical protein FrEUN1fDRAF... 35.8 1.9 gi|86740585|ref|YP_480985.1| hypothetical protein Francci3_1880 ... 35.4 2.8 gi|320531226|ref|ZP_08032210.1| putative toxin-antitoxin system,... 35.4 3.0 gi|146281698|ref|YP_001171851.1| nitrogen fixation negative regu... 34.7 4.8 gi|326476979|gb|EGE00989.1| vacuolar protein sorting protein [Tr... 34.3 6.3 gi|326472159|gb|EGD96168.1| vacuolar protein sorting protein [Tr... 34.3 6.5 >gi|15607264|ref|NP_214636.1| hypothetical protein Rv0122 [Mycobacterium tuberculosis H37Rv] gi|31791301|ref|NP_853794.1| hypothetical protein Mb0127 [Mycobacterium bovis AF2122/97] gi|121636035|ref|YP_976258.1| hypothetical protein BCG_0156 [Mycobacterium bovis BCG str. Pasteur 1173P2] 49 more sequence titlesLength=122 Score = 248 bits (634), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 121/122 (99%), Positives = 122/122 (100%), Gaps = 0/122 (0%) Query 1 LAGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARK 60 +AGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARK Sbjct 1 MAGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARK 60 Query 61 HRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEW 120 HRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEW Sbjct 61 HRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEW 120 Query 121 KR 122 KR Sbjct 121 KR 122 >gi|167966876|ref|ZP_02549153.1| hypothetical protein MtubH3_01950 [Mycobacterium tuberculosis H37Ra] Length=109 Score = 184 bits (466), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 88/90 (98%), Positives = 89/90 (99%), Gaps = 0/90 (0%) Query 1 LAGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARK 60 +AGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARK Sbjct 1 MAGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARK 60 Query 61 HRVSKHRIVAAMRHCGVPVIQEDGSLYYQG 90 HRVSKHRIVAAMRHCGVPVIQEDGSLYYQ Sbjct 61 HRVSKHRIVAAMRHCGVPVIQEDGSLYYQA 90 >gi|308378551|ref|ZP_07482970.2| hypothetical protein TMIG_00407 [Mycobacterium tuberculosis SUMu009] gi|308379701|ref|ZP_07487203.2| hypothetical protein TMJG_01306 [Mycobacterium tuberculosis SUMu010] gi|308352214|gb|EFP41065.1| hypothetical protein TMIG_00407 [Mycobacterium tuberculosis SUMu009] gi|308356179|gb|EFP45030.1| hypothetical protein TMJG_01306 [Mycobacterium tuberculosis SUMu010] Length=74 Score = 151 bits (382), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 73/74 (99%), Positives = 74/74 (100%), Gaps = 0/74 (0%) Query 49 VQRVRVTRNARKHRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDG 108 +QRVRVTRNARKHRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDG Sbjct 1 MQRVRVTRNARKHRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDG 60 Query 109 DLIITHAMPKEWKR 122 DLIITHAMPKEWKR Sbjct 61 DLIITHAMPKEWKR 74 >gi|254549057|ref|ZP_05139504.1| hypothetical protein Mtube_01096 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|323717261|gb|EGB26469.1| hypothetical protein TMMG_00547 [Mycobacterium tuberculosis CDC1551A] Length=60 Score = 125 bits (314), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 59/60 (99%), Positives = 60/60 (100%), Gaps = 0/60 (0%) Query 63 VSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEWKR 122 +SKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEWKR Sbjct 1 MSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEWKR 60 >gi|227548715|ref|ZP_03978764.1| conserved hypothetical protein [Corynebacterium lipophiloflavum DSM 44291] gi|227079208|gb|EEI17171.1| conserved hypothetical protein [Corynebacterium lipophiloflavum DSM 44291] Length=80 Score = 37.7 bits (86), Expect = 0.51, Method: Compositional matrix adjust. Identities = 26/69 (38%), Positives = 38/69 (56%), Gaps = 4/69 (5%) Query 52 VRVTRNARKHRVSKHR-IVAAMRHCGVPVIQEDGSLYYQ---GRDTSGRLTEVVAVEADD 107 +RV +A KH +S+ I AA+ V + +D + + + G DT RL E V V A D Sbjct 1 MRVAASATKHGISEEDGIHAALFPTWVAPLDDDPAQWRELRLGFDTHARLLETVVVVASD 60 Query 108 GDLIITHAM 116 GD ++ HAM Sbjct 61 GDELLIHAM 69 >gi|340793304|ref|YP_004758767.1| hypothetical protein CVAR_0346 [Corynebacterium variabile DSM 44702] gi|340533214|gb|AEK35694.1| hypothetical protein CVAR_0346 [Corynebacterium variabile DSM 44702] Length=100 Score = 37.4 bits (85), Expect = 0.77, Method: Compositional matrix adjust. Identities = 15/28 (54%), Positives = 20/28 (72%), Gaps = 0/28 (0%) Query 90 GRDTSGRLTEVVAVEADDGDLIITHAMP 117 G D +GR+ E +AVE DGD ++ HAMP Sbjct 60 GIDGNGRILEFIAVETSDGDWLVFHAMP 87 >gi|334338334|ref|YP_004543486.1| hypothetical protein Isova_2907 [Isoptericola variabilis 225] gi|334108702|gb|AEG45592.1| hypothetical protein Isova_2907 [Isoptericola variabilis 225] Length=85 Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust. Identities = 26/72 (37%), Positives = 39/72 (55%), Gaps = 8/72 (11%) Query 53 RVTRNARKH----RVSKHRIVAAMRHC--GVPVIQEDGS--LYYQGRDTSGRLTEVVAVE 104 R+ +ARKH R+++ ++ A +H VP+ ED G D SGR+ E+V + Sbjct 3 RLHDSARKHFRRDRLTEAGVLYAAQHSLYQVPLDDEDDPRRWLMLGFDDSGRMLELVVLV 62 Query 105 ADDGDLIITHAM 116 D GD +I HAM Sbjct 63 FDSGDELIIHAM 74 >gi|288923011|ref|ZP_06417166.1| hypothetical protein FrEUN1fDRAFT_6864 [Frankia sp. EUN1f] gi|288345629|gb|EFC80003.1| hypothetical protein FrEUN1fDRAFT_6864 [Frankia sp. EUN1f] Length=81 Score = 35.8 bits (81), Expect = 1.9, Method: Compositional matrix adjust. Identities = 26/75 (35%), Positives = 38/75 (51%), Gaps = 6/75 (8%) Query 52 VRVTRNARKHRVSKHRIVAAMRHCGVPVIQEDGSLYYQ---GRDTSGRLTEVVAVEADDG 108 V + R+ARKH V+ ++ A V +D + + G D SG L E+V + DDG Sbjct 3 VEIHRSARKHGVADADLLHAATRYLVAFALDDENPRRELRLGPDRSGNLLEIVVLLLDDG 62 Query 109 DLIITHAM---PKEW 120 +I +AM PK W Sbjct 63 TELIIYAMRMRPKYW 77 >gi|86740585|ref|YP_480985.1| hypothetical protein Francci3_1880 [Frankia sp. CcI3] gi|86567447|gb|ABD11256.1| conserved hypothetical protein [Frankia sp. CcI3] Length=80 Score = 35.4 bits (80), Expect = 2.8, Method: Compositional matrix adjust. Identities = 24/69 (35%), Positives = 38/69 (56%), Gaps = 4/69 (5%) Query 52 VRVTRNARKHRVSKHRIV-AAMRHCGVPVIQEDGSLYYQ---GRDTSGRLTEVVAVEADD 107 + + R+ARKH V+ I+ AA R+ + +DG + + G +G L E+V + DD Sbjct 1 MEIHRSARKHGVADADILHAAERYVVAYSLDDDGPPWRELRLGPGGAGNLLEIVVLLLDD 60 Query 108 GDLIITHAM 116 G +I HAM Sbjct 61 GTELIIHAM 69 >gi|320531226|ref|ZP_08032210.1| putative toxin-antitoxin system, toxin component [Actinomyces sp. oral taxon 171 str. F0337] gi|320136557|gb|EFW28521.1| putative toxin-antitoxin system, toxin component [Actinomyces sp. oral taxon 171 str. F0337] Length=79 Score = 35.4 bits (80), Expect = 3.0, Method: Compositional matrix adjust. Identities = 23/73 (32%), Positives = 35/73 (48%), Gaps = 13/73 (17%) Query 52 VRVTRNARKHRVS--------KHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVAV 103 ++V +A KH +S HRI + VP Q + G D+ GRL E+V + Sbjct 1 MKVHNSALKHGISAADALYAANHRIYESWPDDDVPAKQ-----FVMGFDSQGRLLELVIL 55 Query 104 EADDGDLIITHAM 116 D G+ ++ HAM Sbjct 56 TFDSGNQLLIHAM 68 >gi|146281698|ref|YP_001171851.1| nitrogen fixation negative regulatory protein [Pseudomonas stutzeri A1501] gi|25136598|emb|CAC44174.3| NifL protein [Pseudomonas stutzeri] gi|145569903|gb|ABP79009.1| nitrogen fixation negative regulatory protein [Pseudomonas stutzeri A1501] Length=537 Score = 34.7 bits (78), Expect = 4.8, Method: Compositional matrix adjust. Identities = 17/58 (30%), Positives = 25/58 (44%), Gaps = 0/58 (0%) Query 12 GWVGLNVTETNRDQCYRVERTTVDALTHPEYRVHTRGVQRVRVTRNARKHRVSKHRIV 69 W G+ V D CY E T L E +H G+ R ++ + RVS R++ Sbjct 113 AWSGMLVNRRKDDSCYLAELTVAPVLDEHERTIHYLGMHRDSSDQHKLEQRVSNQRLI 170 >gi|326476979|gb|EGE00989.1| vacuolar protein sorting protein [Trichophyton equinum CBS 127.97] Length=1458 Score = 34.3 bits (77), Expect = 6.3, Method: Composition-based stats. Identities = 15/36 (42%), Positives = 21/36 (59%), Gaps = 0/36 (0%) Query 87 YYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEWKR 122 Y + DTS E V ++ DDGDL +T K+W+R Sbjct 667 YLERSDTSSGEDETVILKTDDGDLFVTRDHGKKWQR 702 >gi|326472159|gb|EGD96168.1| vacuolar protein sorting protein [Trichophyton tonsurans CBS 112818] Length=1486 Score = 34.3 bits (77), Expect = 6.5, Method: Composition-based stats. Identities = 15/36 (42%), Positives = 21/36 (59%), Gaps = 0/36 (0%) Query 87 YYQGRDTSGRLTEVVAVEADDGDLIITHAMPKEWKR 122 Y + DTS E V ++ DDGDL +T K+W+R Sbjct 695 YLERSDTSSGEDETVILKTDDGDLFVTRDHGKKWQR 730 Lambda K H 0.320 0.133 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 127525862838 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40