BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0125

Length=355
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607267|ref|NP_214639.1|  serine protease PepA [Mycobacterium...   684    0.0   
gi|340625160|ref|YP_004743612.1|  putative serine protease [Mycob...   682    0.0   
gi|253797044|ref|YP_003030045.1|  serine protease pepA [Mycobacte...   652    0.0   
gi|289568019|ref|ZP_06448246.1|  LOW QUALITY PROTEIN: serine prot...   645    0.0   
gi|167970242|ref|ZP_02552519.1|  serine protease pepA [Mycobacter...   628    5e-178
gi|183980355|ref|YP_001848646.1|  serine protease PepA [Mycobacte...   579    2e-163
gi|240168112|ref|ZP_04746771.1|  putative serine protease [Mycoba...   568    4e-160
gi|118619849|ref|YP_908181.1|  serine protease PepA [Mycobacteriu...   555    3e-156
gi|15828433|ref|NP_302696.1|  serine protease [Mycobacterium lepr...   474    9e-132
gi|296167291|ref|ZP_06849693.1|  serine protease PepA [Mycobacter...   464    7e-129
gi|254777533|ref|ZP_05219049.1|  PepA [Mycobacterium avium subsp....   460    1e-127
gi|118465668|ref|YP_884304.1|  trypsin [Mycobacterium avium 104] ...   459    4e-127
gi|41409625|ref|NP_962461.1|  PepA [Mycobacterium avium subsp. pa...   456    2e-126
gi|342859465|ref|ZP_08716119.1|  PepA [Mycobacterium colombiense ...   454    8e-126
gi|289441497|ref|ZP_06431241.1|  serine protease pepA [Mycobacter...   452    5e-125
gi|254822400|ref|ZP_05227401.1|  PepA [Mycobacterium intracellula...   434    8e-120
gi|333992824|ref|YP_004525438.1|  serine protease PepA [Mycobacte...   390    2e-106
gi|300789371|ref|YP_003769662.1|  serine protease [Amycolatopsis ...   270    2e-70 
gi|118468378|ref|YP_890507.1|  trypsin [Mycobacterium smegmatis s...   261    1e-67 
gi|108801875|ref|YP_642072.1|  peptidase S1 and S6, chymotrypsin/...   257    2e-66 
gi|126437843|ref|YP_001073534.1|  peptidase S1 and S6, chymotryps...   256    3e-66 
gi|315446395|ref|YP_004079274.1|  trypsin-like serine protease wi...   254    1e-65 
gi|339293189|gb|AEJ45300.1|  serine protease pepA [Mycobacterium ...   252    5e-65 
gi|120406480|ref|YP_956309.1|  PDZ/DHR/GLGF domain-containing pro...   252    6e-65 
gi|145221870|ref|YP_001132548.1|  PDZ/DHR/GLGF domain-containing ...   251    1e-64 
gi|111021065|ref|YP_704037.1|  serine protease [Rhodococcus josti...   236    4e-60 
gi|226363367|ref|YP_002781149.1|  S1C family peptidase [Rhodococc...   235    1e-59 
gi|148273618|ref|YP_001223179.1|  secreted serine protease [Clavi...   233    5e-59 
gi|302527941|ref|ZP_07280283.1|  predicted protein [Streptomyces ...   228    9e-58 
gi|229492648|ref|ZP_04386451.1|  trypsin [Rhodococcus erythropoli...   220    3e-55 
gi|226303734|ref|YP_002763692.1|  S1 family peptidase [Rhodococcu...   214    1e-53 
gi|170782706|ref|YP_001711040.1|  putative protease [Clavibacter ...   214    3e-53 
gi|325675110|ref|ZP_08154796.1|  serine protease [Rhodococcus equ...   198    1e-48 
gi|312137738|ref|YP_004005074.1|  serine peptidase [Rhodococcus e...   198    1e-48 
gi|54027199|ref|YP_121441.1|  putative protease [Nocardia farcini...   194    2e-47 
gi|332671091|ref|YP_004454099.1|  PDZ/DHR/GLGF domain-containing ...   190    4e-46 
gi|258654784|ref|YP_003203940.1|  peptidase S1 and S6 chymotrypsi...   186    4e-45 
gi|331696262|ref|YP_004332501.1|  PDZ/DHR/GLGF domain-containing ...   179    9e-43 
gi|339293190|gb|AEJ45301.1|  serine protease pepA [Mycobacterium ...   178    1e-42 
gi|336321368|ref|YP_004601336.1|  PDZ/DHR/GLGF domain-containing ...   178    1e-42 
gi|297625432|ref|YP_003687195.1|  secreted serine protease, tryps...   177    2e-42 
gi|256371362|ref|YP_003109186.1|  PDZ/DHR/GLGF domain-containing ...   174    2e-41 
gi|309811136|ref|ZP_07704933.1|  trypsin [Dermacoccus sp. Ellin18...   169    5e-40 
gi|326334041|ref|ZP_08200270.1|  putative serine protease [Nocard...   164    3e-38 
gi|289705249|ref|ZP_06501648.1|  trypsin [Micrococcus luteus SK58...   159    5e-37 
gi|239918048|ref|YP_002957606.1|  trypsin-like serine protease wi...   154    3e-35 
gi|336178408|ref|YP_004583783.1|  peptidase S1 and S6 chymotrypsi...   153    3e-35 
gi|256371520|ref|YP_003109344.1|  peptidase S1 and S6 chymotrypsi...   153    4e-35 
gi|269929247|ref|YP_003321568.1|  HtrA2 peptidase [Sphaerobacter ...   147    2e-33 
gi|240169346|ref|ZP_04748005.1|  heat shock protein HtrA, putativ...   145    7e-33 


>gi|15607267|ref|NP_214639.1| serine protease PepA [Mycobacterium tuberculosis H37Rv]
 gi|15839506|ref|NP_334543.1| serine protease, putative [Mycobacterium tuberculosis CDC1551]
 gi|31791304|ref|NP_853797.1| serine protease PepA [Mycobacterium bovis AF2122/97]
 68 more sequence titles
 Length=355

 Score =  684 bits (1765),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 355/355 (100%), Positives = 355/355 (100%), Gaps = 0/355 (0%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60
            MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG
Sbjct  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60

Query  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120
            PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG
Sbjct  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120

Query  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180
            YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV
Sbjct  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180

Query  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240
            QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA
Sbjct  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240

Query  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300
            IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST
Sbjct  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300

Query  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA
Sbjct  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355


>gi|340625160|ref|YP_004743612.1| putative serine protease [Mycobacterium canettii CIPT 140010059]
 gi|340003350|emb|CCC42469.1| putative serine protease PEPA (serine proteinase) (MTB32A) [Mycobacterium 
canettii CIPT 140010059]
Length=355

 Score =  682 bits (1760),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 353/355 (99%), Positives = 355/355 (100%), Gaps = 0/355 (0%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60
            MSNSRRR+LRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG
Sbjct  1    MSNSRRRALRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60

Query  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120
            PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG
Sbjct  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120

Query  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180
            YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV
Sbjct  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180

Query  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240
            QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA
Sbjct  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240

Query  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300
            IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARV+RVVGSAPAASLGIST
Sbjct  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVERVVGSAPAASLGIST  300

Query  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA
Sbjct  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355


>gi|253797044|ref|YP_003030045.1| serine protease pepA [Mycobacterium tuberculosis KZN 1435]
 gi|253318547|gb|ACT23150.1| serine protease pepA [Mycobacterium tuberculosis KZN 1435]
Length=342

 Score =  652 bits (1681),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 341/342 (99%), Positives = 342/342 (100%), Gaps = 0/342 (0%)

Query  14   LLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYN  73
            +LSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYN
Sbjct  1    MLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYN  60

Query  74   NAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLR  133
            NAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLR
Sbjct  61   NAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLR  120

Query  134  GAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETL  193
            GAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETL
Sbjct  121  GAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETL  180

Query  194  NGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQI  253
            NGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQI
Sbjct  181  NGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQI  240

Query  254  RSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPIN  313
            RSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPIN
Sbjct  241  RSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPIN  300

Query  314  SATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            SATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA
Sbjct  301  SATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  342


>gi|289568019|ref|ZP_06448246.1| LOW QUALITY PROTEIN: serine protease pepA [Mycobacterium tuberculosis 
T17]
 gi|289541772|gb|EFD45421.1| LOW QUALITY PROTEIN: serine protease pepA [Mycobacterium tuberculosis 
T17]
Length=335

 Score =  645 bits (1664),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 335/335 (100%), Positives = 335/335 (100%), Gaps = 0/335 (0%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60
            MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG
Sbjct  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60

Query  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120
            PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG
Sbjct  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120

Query  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180
            YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV
Sbjct  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180

Query  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240
            QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA
Sbjct  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240

Query  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300
            IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST
Sbjct  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300

Query  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTW  335
            GDVITAVDGAPINSATAMADALNGHHPGDVISVTW
Sbjct  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTW  335


>gi|167970242|ref|ZP_02552519.1| serine protease pepA [Mycobacterium tuberculosis H37Ra]
Length=328

 Score =  628 bits (1619),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 327/327 (100%), Positives = 327/327 (100%), Gaps = 0/327 (0%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60
            MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG
Sbjct  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVG  60

Query  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120
            PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG
Sbjct  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120

Query  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180
            YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV
Sbjct  121  YDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180

Query  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240
            QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA
Sbjct  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFA  240

Query  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300
            IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST
Sbjct  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGIST  300

Query  301  GDVITAVDGAPINSATAMADALNGHHP  327
            GDVITAVDGAPINSATAMADALNGHHP
Sbjct  301  GDVITAVDGAPINSATAMADALNGHHP  327


>gi|183980355|ref|YP_001848646.1| serine protease PepA [Mycobacterium marinum M]
 gi|183173681|gb|ACC38791.1| serine protease PepA [Mycobacterium marinum M]
Length=357

 Score =  579 bits (1493),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 296/357 (83%), Positives = 326/357 (92%), Gaps = 2/357 (0%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLAT--APAQAAPPALSQDRFADFPALPLDPSAMVAQ  58
            MS  R  S RWSWL++VLA +GLGLAT  APA AAP  L+ DRFADFP LPLDPSAMVAQ
Sbjct  1    MSKLRHHSPRWSWLVAVLAVLGLGLATVPAPALAAPSNLALDRFADFPTLPLDPSAMVAQ  60

Query  59   VGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDV  118
            VGPQVVN+NTKLGYNNAVGAGTGI+IDP GVVLTNNHVI+GATDI+ FSVG G+TYGVDV
Sbjct  61   VGPQVVNVNTKLGYNNAVGAGTGIIIDPAGVVLTNNHVISGATDISVFSVGDGRTYGVDV  120

Query  119  VGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQ  178
            VGYDRT+DVAVLQ+RGAGGLP+AAIGGGV+VGEP+VAMGN+GGQGGTPRAVPGRVVAL Q
Sbjct  121  VGYDRTRDVAVLQMRGAGGLPAAAIGGGVSVGEPIVAMGNTGGQGGTPRAVPGRVVALDQ  180

Query  179  TVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQG  238
            TV+ASD+LTGAEETLNGLIQ DAAI PGDSGGP+VN +GQVVGMNTAASDNFQ+S GG G
Sbjct  181  TVEASDALTGAEETLNGLIQVDAAIAPGDSGGPIVNNMGQVVGMNTAASDNFQMSGGGTG  240

Query  239  FAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGI  298
            FAIPIGQAM IAGQIRSGGGSPTVHIGPTAFLGLGVVDNNG GA+V RVVGSAPAA +GI
Sbjct  241  FAIPIGQAMGIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGTGAKVARVVGSAPAAVVGI  300

Query  299  STGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            STGD+ITA+ GAPINSATAM+DALNGHHPGD++S++W + SGG RT NVTLAEGPPA
Sbjct  301  STGDIITALGGAPINSATAMSDALNGHHPGDIVSISWTSNSGGQRTENVTLAEGPPA  357


>gi|240168112|ref|ZP_04746771.1| putative serine protease [Mycobacterium kansasii ATCC 12478]
Length=357

 Score =  568 bits (1464),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 292/357 (82%), Positives = 328/357 (92%), Gaps = 2/357 (0%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPA--LSQDRFADFPALPLDPSAMVAQ  58
            MS  R R +RWSWL++++A +GLGLAT PA A+      + DRFAD+P+LPLDPSA+V Q
Sbjct  1    MSKDRHRPVRWSWLVAIVAVLGLGLATPPAPASAAPSTFALDRFADYPSLPLDPSALVGQ  60

Query  59   VGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDV  118
            VGPQ+VNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVI+GATDI+AF VG+GQTYGVDV
Sbjct  61   VGPQIVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVISGATDISAFDVGNGQTYGVDV  120

Query  119  VGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQ  178
            VGYDRTQD+AVLQLRGAGGLP+AAIGGGV++GEP+VA+GN+GGQGGTPRAVPGRVVAL Q
Sbjct  121  VGYDRTQDIAVLQLRGAGGLPTAAIGGGVSIGEPIVALGNTGGQGGTPRAVPGRVVALNQ  180

Query  179  TVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQG  238
            TVQASD+LTGAEETLNGLIQ DAAI+PGDSGGP+VN  GQVVG+NTAASDNFQLSQGGQG
Sbjct  181  TVQASDALTGAEETLNGLIQVDAAIRPGDSGGPIVNSQGQVVGINTAASDNFQLSQGGQG  240

Query  239  FAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGI  298
            FAIPIGQAMAIA QIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVG+APAAS+GI
Sbjct  241  FAIPIGQAMAIANQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGTAPAASIGI  300

Query  299  STGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            S GDV+TAVDG  I+SATA++D LNGHHPGDV+S++W +KSG  RT NVTLAEGPPA
Sbjct  301  SNGDVVTAVDGIAISSATALSDVLNGHHPGDVVSISWLSKSGVARTENVTLAEGPPA  357


>gi|118619849|ref|YP_908181.1| serine protease PepA [Mycobacterium ulcerans Agy99]
 gi|118571959|gb|ABL06710.1| serine protease PepA [Mycobacterium ulcerans Agy99]
Length=343

 Score =  555 bits (1431),  Expect = 3e-156, Method: Compositional matrix adjust.
 Identities = 285/343 (84%), Positives = 315/343 (92%), Gaps = 2/343 (0%)

Query  15   LSVLAAVGLGLAT--APAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGY  72
            ++VLA +GLGLAT  APA AA   L+ DRFADFP LPLDPSAMVAQVGPQVVN+NTKLGY
Sbjct  1    MAVLAVLGLGLATVPAPAHAASSNLALDRFADFPTLPLDPSAMVAQVGPQVVNVNTKLGY  60

Query  73   NNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQL  132
            NNAVGAGTGI+IDP GVVLTNNHVI+GATDI+ FSVG G+TYGVDVVGYDRT+DVAVLQ+
Sbjct  61   NNAVGAGTGIIIDPAGVVLTNNHVISGATDISVFSVGDGRTYGVDVVGYDRTRDVAVLQM  120

Query  133  RGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEET  192
            RGAGGLP+AAIGGGV+VGEP+VAMGN+GGQGGTPRAVPGRVVAL QTV+ASD+LTGAEET
Sbjct  121  RGAGGLPAAAIGGGVSVGEPIVAMGNTGGQGGTPRAVPGRVVALDQTVEASDALTGAEET  180

Query  193  LNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQ  252
            LNGLIQ DAAI PGDSGGP+VN +GQVVGMNTAASDNFQ+S GG GFAIPIGQAM IAGQ
Sbjct  181  LNGLIQVDAAIAPGDSGGPIVNNMGQVVGMNTAASDNFQMSGGGTGFAIPIGQAMGIAGQ  240

Query  253  IRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPI  312
            IRSGGGSPTVHIGPTAFLGLGVVDNN  GA+V RVVGSAPAA +GISTGD+ITA+ GAPI
Sbjct  241  IRSGGGSPTVHIGPTAFLGLGVVDNNDTGAKVARVVGSAPAAVVGISTGDIITALGGAPI  300

Query  313  NSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            NSATAM+DALNGHHPGD++S++W + SGG RT NVTLAEGPPA
Sbjct  301  NSATAMSDALNGHHPGDIVSISWTSSSGGQRTENVTLAEGPPA  343


>gi|15828433|ref|NP_302696.1| serine protease [Mycobacterium leprae TN]
 gi|221230910|ref|YP_002504326.1| putative secreted serine protease [Mycobacterium leprae Br4923]
 gi|13093863|emb|CAC32191.1| probable secreted serine protease [Mycobacterium leprae]
 gi|219934017|emb|CAR72759.1| probable secreted serine protease [Mycobacterium leprae Br4923]
Length=354

 Score =  474 bits (1220),  Expect = 9e-132, Method: Compositional matrix adjust.
 Identities = 250/358 (70%), Positives = 292/358 (82%), Gaps = 7/358 (1%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPP---ALSQDRFADFPALPLDPSAMVA  57
            MS    RSL  SWL+S LAA+GL LA  P  A P     L+ DRF++ P LPL+P+AMVA
Sbjct  1    MSRQPHRSLWRSWLVSTLAALGLSLAVVPGSATPSGPSTLALDRFSNRPPLPLNPAAMVA  60

Query  58   QVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVD  117
               PQVVNI+T+LGYN+AVGAGTGIVID +GVVLTNNHVI+GATDI+AF VG+G+TYGVD
Sbjct  61   ---PQVVNISTRLGYNSAVGAGTGIVIDSSGVVLTNNHVISGATDISAFDVGNGKTYGVD  117

Query  118  VVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALG  177
            VVGYDRTQDVAVLQLRGA  LP+A IGG VA+GEP+VA+GN+GGQGG P  +PGRVVAL 
Sbjct  118  VVGYDRTQDVAVLQLRGASNLPTAVIGGDVAIGEPIVALGNTGGQGGLPSVLPGRVVALN  177

Query  178  QTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ  237
            QTVQAS+ LTGA+ETL+GLIQ DA I+PGDSGGPVVN  GQVVGMNTAA+DN+++  GGQ
Sbjct  178  QTVQASEPLTGAQETLSGLIQVDAPIKPGDSGGPVVNSRGQVVGMNTAATDNYKM-LGGQ  236

Query  238  GFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLG  297
            GFAIPIGQAM + G IRSG GS TVHIGPTAF GLGV+DNNGNGARV RVV + PAA  G
Sbjct  237  GFAIPIGQAMEVVGAIRSGAGSNTVHIGPTAFFGLGVLDNNGNGARVARVVATGPAAMAG  296

Query  298  ISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            IS GD+IT+VDG PI+ ATAM + L  HHPG+ ++V +++  GG  T NVTLAEGPPA
Sbjct  297  ISVGDIITSVDGVPISEATAMTNVLVPHHPGETVAVNYRSAGGGDLTANVTLAEGPPA  354


>gi|296167291|ref|ZP_06849693.1| serine protease PepA [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897235|gb|EFG76839.1| serine protease PepA [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=349

 Score =  464 bits (1195),  Expect = 7e-129, Method: Compositional matrix adjust.
 Identities = 247/334 (74%), Positives = 280/334 (84%), Gaps = 8/334 (2%)

Query  22   GLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTG  81
            GLGL  APA A+P   +Q      P  PLDP+A+V QVGPQVVNINTK GYNNAVGAGTG
Sbjct  24   GLGLGIAPAAASP--FTQ------PRAPLDPAALVGQVGPQVVNINTKFGYNNAVGAGTG  75

Query  82   IVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSA  141
            IVIDPNGVVLTNNHVI+GATDI+AF VG+GQTY VDVVGYDRTQDVAVLQLRGA GLP+A
Sbjct  76   IVIDPNGVVLTNNHVISGATDISAFDVGNGQTYAVDVVGYDRTQDVAVLQLRGAAGLPTA  135

Query  142  AIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDA  201
            AIGGGVAVGEPVVAMGN+GGQGGTP AV G+V+AL QTV A+D+LTGA E+L GLIQ D 
Sbjct  136  AIGGGVAVGEPVVAMGNAGGQGGTPSAVSGKVIALNQTVSATDTLTGANESLGGLIQADT  195

Query  202  AIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPT  261
             I+PGDSGGP+VN  GQVVG+NTAA+DN+++S GGQGFAIPIG+AM +AGQIRSG GS T
Sbjct  196  PIRPGDSGGPLVNNQGQVVGVNTAATDNYKMSGGGQGFAIPIGRAMGVAGQIRSGAGSNT  255

Query  262  VHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADA  321
            VH+GPTAFLGLGV D++GNGARV+RVV S PAA+ GIS GDVITAVD  PIN AT+M D 
Sbjct  256  VHVGPTAFLGLGVTDSDGNGARVERVVTSGPAAAAGISPGDVITAVDNVPINGATSMTDV  315

Query  322  LNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            L  HHPGD I+V +++  GG RT  V LAEGPPA
Sbjct  316  LVPHHPGDTIAVHYRSAGGGDRTAIVALAEGPPA  349


>gi|254777533|ref|ZP_05219049.1| PepA [Mycobacterium avium subsp. avium ATCC 25291]
Length=360

 Score =  460 bits (1184),  Expect = 1e-127, Method: Compositional matrix adjust.
 Identities = 256/361 (71%), Positives = 296/361 (82%), Gaps = 7/361 (1%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLAT------APAQAAPPALSQDRFADFPALPLDPSA  54
            MS S  RS+ WSWL+ VL  VGLGL        APA AAP  L+ DRFAD P  P+DPSA
Sbjct  1    MSKSHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPSA  60

Query  55   MVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTY  114
            MV QVGPQVVNI+TK GYNNAVGAGTGIVIDPNGVVLTNNHVI+GAT+I+AF VG+GQTY
Sbjct  61   MVGQVGPQVVNIDTKFGYNNAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQTY  120

Query  115  GVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVV  174
             VDVVGYDRTQD+AVLQLRGA GLP+A IGG   VGEP+VA+GN GGQGGTP AV G+VV
Sbjct  121  AVDVVGYDRTQDIAVLQLRGATGLPTATIGGEATVGEPIVALGNVGGQGGTPNAVAGKVV  180

Query  175  ALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQ  234
            AL Q+V A+D+LTGA+E L GLIQ DA I+PGDSGGP+VN  GQV+G++TAA+D++++S 
Sbjct  181  ALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMS-  239

Query  235  GGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAA  294
            GGQGFAIPIG+AMA+A QIRSG GS TVHIGPTAFLGLGV DNNGNGARVQRVV + PAA
Sbjct  240  GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPAA  299

Query  295  SLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPP  354
            + GI+ GDVIT VD  PIN AT+M + L  HHPGD I+V +++  GG RT N+TLAEGPP
Sbjct  300  AAGIAPGDVITGVDTVPINGATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGPP  359

Query  355  A  355
            A
Sbjct  360  A  360


>gi|118465668|ref|YP_884304.1| trypsin [Mycobacterium avium 104]
 gi|118166955|gb|ABK67852.1| Trypsin [Mycobacterium avium 104]
Length=371

 Score =  459 bits (1180),  Expect = 4e-127, Method: Compositional matrix adjust.
 Identities = 257/362 (71%), Positives = 297/362 (83%), Gaps = 8/362 (2%)

Query  1    MSNSRR-RSLRWSWLLSVLAAVGLGLAT------APAQAAPPALSQDRFADFPALPLDPS  53
            MS S   RS+ WSWL+ VL  VGLGL        APA AAP  L+ DRFAD P  P+DPS
Sbjct  11   MSKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPS  70

Query  54   AMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQT  113
            AMV QVGPQVVNI+TK GYNNAVGAGTGIVIDPNGVVLTNNHVI+GAT+I+AF VG+GQT
Sbjct  71   AMVGQVGPQVVNIDTKFGYNNAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQT  130

Query  114  YGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRV  173
            Y VDVVGYDRTQD+AVLQLRGA GLP+A IGG   VGEP+VA+GN GGQGGTP AV G+V
Sbjct  131  YAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPIVALGNVGGQGGTPNAVAGKV  190

Query  174  VALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLS  233
            VAL Q+V A+D+LTGA+E L GLIQ DA I+PGDSGGP+VNG GQV+G++TAA+D++++S
Sbjct  191  VALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNGAGQVIGVDTAATDSYKMS  250

Query  234  QGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPA  293
             GGQGFAIPIG+AMA+A QIRSG GS TVHIGPTAFLGLGV DNNGNGARVQRVV + PA
Sbjct  251  -GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPA  309

Query  294  ASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            A+ GI+ GDVIT VD  PIN AT+M + L  HHPGD I+V +++  GG RT N+TLAEGP
Sbjct  310  AAAGIAPGDVITGVDTVPINGATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGP  369

Query  354  PA  355
            PA
Sbjct  370  PA  371


>gi|41409625|ref|NP_962461.1| PepA [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|505551|emb|CAA80638.1| 34KDa protein [Mycobacterium avium subsp. paratuberculosis]
 gi|41398456|gb|AAS06077.1| PepA [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|336459938|gb|EGO38850.1| trypsin-like serine protease with C-terminal PDZ domain-containing 
protein [Mycobacterium avium subsp. paratuberculosis S397]
Length=361

 Score =  456 bits (1174),  Expect = 2e-126, Method: Compositional matrix adjust.
 Identities = 256/362 (71%), Positives = 296/362 (82%), Gaps = 8/362 (2%)

Query  1    MSNSRR-RSLRWSWLLSVLAAVGLGLAT------APAQAAPPALSQDRFADFPALPLDPS  53
            MS S   RS+ WSWL+ VL  VGLGL        APA AAP  L+ DRFAD P  P+DPS
Sbjct  1    MSKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPS  60

Query  54   AMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQT  113
            AMV QVGPQVVNI+TK GYNNAVGAGTGIVIDPNGVVLTNNHVI+GAT+I+AF VG+GQT
Sbjct  61   AMVGQVGPQVVNIDTKFGYNNAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQT  120

Query  114  YGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRV  173
            Y VDVVGYDRTQD+AVLQLRGA GLP+A IGG   VGEP+VA+GN GGQGGTP AV G+V
Sbjct  121  YAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPIVALGNVGGQGGTPNAVAGKV  180

Query  174  VALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLS  233
            VAL Q+V A+D+LTGA+E L GLIQ DA I+PGDSGGP+VN  GQV+G++TAA+D++++S
Sbjct  181  VALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMS  240

Query  234  QGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPA  293
             GGQGFAIPIG+AMA+A QIRSG GS TVHIGPTAFLGLGV DNNGNGARVQRVV + PA
Sbjct  241  -GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPA  299

Query  294  ASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            A+ GI+ GDVIT VD  PIN AT+M + L  HHPGD I+V +++  GG RT N+TLAEGP
Sbjct  300  AAAGIAPGDVITGVDTVPINGATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGP  359

Query  354  PA  355
            PA
Sbjct  360  PA  361


>gi|342859465|ref|ZP_08716119.1| PepA [Mycobacterium colombiense CECT 3035]
 gi|342133706|gb|EGT86909.1| PepA [Mycobacterium colombiense CECT 3035]
Length=360

 Score =  454 bits (1169),  Expect = 8e-126, Method: Compositional matrix adjust.
 Identities = 250/361 (70%), Positives = 292/361 (81%), Gaps = 7/361 (1%)

Query  1    MSNSRRRSLRWSWLLSVLAAVGLGLAT------APAQAAPPALSQDRFADFPALPLDPSA  54
            MS S+ R + WSWL+SVL  VGLGL        APA  AP   + DRF D P  PLDPSA
Sbjct  1    MSKSQHRPVLWSWLVSVLTVVGLGLGLGSGVGLAPASGAPSNFALDRFTDRPQAPLDPSA  60

Query  55   MVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTY  114
            MV QVGPQVVNI+TK GYNNAVGAGTGIVIDPNGVVLTNNHVI+GATDI+AF VG+GQTY
Sbjct  61   MVGQVGPQVVNIDTKFGYNNAVGAGTGIVIDPNGVVLTNNHVISGATDISAFDVGNGQTY  120

Query  115  GVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVV  174
             VDVVGYDRTQD+AVLQLRGA GLP+AAIGG   VGEP+VA+GN  GQGGTP AV G+VV
Sbjct  121  AVDVVGYDRTQDIAVLQLRGASGLPTAAIGGEATVGEPIVALGNVNGQGGTPNAVTGKVV  180

Query  175  ALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQ  234
            AL Q+V A+D+LTGA+E+L GLIQ DA I+PGDSGGP+VN  GQV+G++TAA+D++++S 
Sbjct  181  ALNQSVSATDTLTGAQESLGGLIQADAPIKPGDSGGPMVNNAGQVIGVDTAATDSYKMS-  239

Query  235  GGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAA  294
            GGQGFAIPIG+AM +AGQIRSG GS TVHIGPTAFLGLGV+DNNG GARVQRVV + PA 
Sbjct  240  GGQGFAIPIGRAMGVAGQIRSGAGSNTVHIGPTAFLGLGVMDNNGTGARVQRVVNAGPAG  299

Query  295  SLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPP  354
            + GI+ GD+IT VD   I  AT+M + L  HHPGD I+V +++  GG RT N+TLAEGPP
Sbjct  300  AAGIAPGDLITGVDNVAITGATSMTEVLVPHHPGDTIAVHYRSNDGGERTANITLAEGPP  359

Query  355  A  355
            A
Sbjct  360  A  360


>gi|289441497|ref|ZP_06431241.1| serine protease pepA [Mycobacterium tuberculosis T46]
 gi|289414416|gb|EFD11656.1| serine protease pepA [Mycobacterium tuberculosis T46]
Length=238

 Score =  452 bits (1162),  Expect = 5e-125, Method: Compositional matrix adjust.
 Identities = 237/238 (99%), Positives = 238/238 (100%), Gaps = 0/238 (0%)

Query  118  VVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALG  177
            +VGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALG
Sbjct  1    MVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALG  60

Query  178  QTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ  237
            QTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ
Sbjct  61   QTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ  120

Query  238  GFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLG  297
            GFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLG
Sbjct  121  GFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLG  180

Query  298  ISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            ISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA
Sbjct  181  ISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  238


>gi|254822400|ref|ZP_05227401.1| PepA [Mycobacterium intracellulare ATCC 13950]
Length=348

 Score =  434 bits (1117),  Expect = 8e-120, Method: Compositional matrix adjust.
 Identities = 236/341 (70%), Positives = 277/341 (82%), Gaps = 16/341 (4%)

Query  15   LSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYNN  74
            L + A +GLG+ATA                 PALPLDPSAMV QVGPQVVNI+TK GYNN
Sbjct  24   LGLDAGIGLGMATASP---------------PALPLDPSAMVGQVGPQVVNIDTKFGYNN  68

Query  75   AVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRG  134
            AVGAGTGIVIDPNGVVLTNNHVI+GATDI+AF+VG+GQTY VDVVGYDRTQD+AVLQLRG
Sbjct  69   AVGAGTGIVIDPNGVVLTNNHVISGATDISAFAVGNGQTYAVDVVGYDRTQDIAVLQLRG  128

Query  135  AGGLPSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLN  194
            A GLP+AAIGG   VGEP+VA+GN+GGQGGTP AV G+V+AL Q+V A+D+LTGA+E L 
Sbjct  129  AAGLPTAAIGGEARVGEPIVALGNAGGQGGTPSAVTGKVLALNQSVSATDTLTGAQENLG  188

Query  195  GLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQIR  254
            GLIQ DA I+PGDSGGP+VN  GQV+G++TAA+D++++S GGQGFAIPIG+AM +A QIR
Sbjct  189  GLIQADAPIRPGDSGGPMVNSAGQVIGVDTAATDSYKMS-GGQGFAIPIGRAMGVANQIR  247

Query  255  SGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINS  314
            SG GS TVHIGPTAFLGLGV+DNNGNGARVQRVV   PA + GI+ GDVIT VD   I  
Sbjct  248  SGAGSNTVHIGPTAFLGLGVMDNNGNGARVQRVVNGGPAGAAGIAAGDVITGVDNVAITG  307

Query  315  ATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            AT+M + L  HHPGD I+V +++  GG RT N+TLAEGPPA
Sbjct  308  ATSMTEVLVPHHPGDTIAVHYRSTDGGDRTANITLAEGPPA  348


>gi|333992824|ref|YP_004525438.1| serine protease PepA [Mycobacterium sp. JDM601]
 gi|333488792|gb|AEF38184.1| serine protease PepA [Mycobacterium sp. JDM601]
Length=321

 Score =  390 bits (1002),  Expect = 2e-106, Method: Compositional matrix adjust.
 Identities = 205/328 (63%), Positives = 254/328 (78%), Gaps = 13/328 (3%)

Query  29   PAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNG  88
            P QAAP           PA PLDPSAMVAQVGP VVNI+ ++GY +AVGAGTGIV+DP+G
Sbjct  2    PVQAAP---------TLPAPPLDPSAMVAQVGPAVVNIDAQMGYQSAVGAGTGIVLDPSG  52

Query  89   VVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIG--GG  146
            +VLTNNHV+AGAT +   SVG+GQ+Y VDV+G+DR+ DVAVLQLRGA GLPSA IG    
Sbjct  53   IVLTNNHVVAGATSLTVVSVGNGQSYDVDVLGFDRSHDVAVLQLRGASGLPSANIGDSSK  112

Query  147  VAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPG  206
            VA+G+PVVAMGN+GGQGGTP AVPG+V+ L QTV A+D LTG  ETL  +I+ D AI+PG
Sbjct  113  VAIGDPVVAMGNAGGQGGTPSAVPGKVIGLNQTVSAADELTGNTETLTNMIKADTAIRPG  172

Query  207  DSGGPVVNGLGQVVGMNTAASDNFQLSQ-GGQGFAIPIGQAMAIAGQIRSGGGSPTVHIG  265
            DSGGP+VN  GQV+GMNTAASDN++ +Q GG+G+AIPI QAMAIAGQIR+G  SPTVHIG
Sbjct  173  DSGGPMVNAAGQVIGMNTAASDNYKFAQPGGEGYAIPINQAMAIAGQIRAGISSPTVHIG  232

Query  266  PTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGH  325
             TAF+G+GVVD+NG  ARV +V+   PAA  GI+  D+IT+V+G P+NS T + D L+  
Sbjct  233  ETAFMGVGVVDSNG-AARVAQVLEGTPAAESGIARDDIITSVNGRPVNSPTDLTDVLDQR  291

Query  326  HPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            HPGD I+++W+T  G   +  +TL  GP
Sbjct  292  HPGDTITLSWRTPMGSEHSATITLVPGP  319


>gi|300789371|ref|YP_003769662.1| serine protease [Amycolatopsis mediterranei U32]
 gi|299798885|gb|ADJ49260.1| putative serine protease [Amycolatopsis mediterranei U32]
 gi|340531018|gb|AEK46223.1| serine protease [Amycolatopsis mediterranei S699]
Length=458

 Score =  270 bits (690),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 162/311 (53%), Positives = 212/311 (69%), Gaps = 8/311 (2%)

Query  50   LDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVG  109
            LD  A+ A+V P +VNINT+LG   A  AGTGIV+  +G VLTNNHV+AGAT I   S+G
Sbjct  147  LDADAVSAKVNPAIVNINTELGLQGAAAAGTGIVLTADGEVLTNNHVVAGATSIKVTSIG  206

Query  110  SGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIG--GGVAVGEPVVAMGNSGGQGGTPR  167
            +G TY   VVGYDR +DVAVLQL+GA GLP+A+IG    V VG+ ++ +GN+GG+GG P 
Sbjct  207  TGDTYKAQVVGYDRAEDVAVLQLQGASGLPTASIGDSSAVQVGDQILGLGNAGGRGGNPV  266

Query  168  AVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAAS  227
              PG V AL Q++ ASD  +G+ E L GLIQ  A I+ GDSGGP+VN   QV+G++TAAS
Sbjct  267  PAPGTVTALNQSITASDESSGSSEQLTGLIQVRANIESGDSGGPLVNANAQVIGVDTAAS  326

Query  228  DNFQLS-----QGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGA  282
              +QL+       GQGFAIPI QA+ IA +I +G  S  +HIG TAF+G+ V D  G GA
Sbjct  327  TGYQLNGRRSGGAGQGFAIPINQAVDIAHKIVAGQASDKIHIGKTAFIGVSVTDGQG-GA  385

Query  283  RVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGT  342
            +V+ VV   PA   G++ GDVITA+DG P  SATA+ + ++ HHPGD +++T    +GG 
Sbjct  386  KVREVVQRGPAQKAGLAAGDVITAIDGKPTGSATALTNVMDTHHPGDRLTLTVAGAAGGQ  445

Query  343  RTGNVTLAEGP  353
            +   V   EGP
Sbjct  446  QQLQVNAIEGP  456


>gi|118468378|ref|YP_890507.1| trypsin [Mycobacterium smegmatis str. MC2 155]
 gi|118169665|gb|ABK70561.1| Trypsin [Mycobacterium smegmatis str. MC2 155]
Length=340

 Score =  261 bits (667),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 146/293 (50%), Positives = 195/293 (67%), Gaps = 6/293 (2%)

Query  65   NINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRT  124
             I+T + Y  A G GTG V+ PNG VLTN HV+ GA  INA    +G ++  D+VGY+R 
Sbjct  50   RIDTVVDYQQAYGVGTGFVLSPNGEVLTNYHVVQGANTINATV--NGASFMADLVGYNRR  107

Query  125  QDVAVLQLRGAGGLPSAAIGGGVAV--GEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQA  182
             D+AVLQLRGAGGLP+A+IG   ++  GEPVVA+GN+ G         G V A G+TV A
Sbjct  108  ADIAVLQLRGAGGLPTASIGDSRSLVEGEPVVALGNAYGSNAPLTREVGTVTAFGRTVNA  167

Query  183  SDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGFAIP  242
             DSLTG ++ L GLI+F A ++ GDSGGPVV+G GQVVG+ TAAS NF++  GG+GFAIP
Sbjct  168  EDSLTGTKDELTGLIEFAAPVRAGDSGGPVVDGAGQVVGVTTAASVNFRMGPGGKGFAIP  227

Query  243  IGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV--VDNNGNGARVQRVVGSAPAASLGIST  300
            I  AMA+A QIRS   SP VHIGP   LG+GV     +G G  +Q V+   PA + G+  
Sbjct  228  INDAMAVANQIRSRTPSPEVHIGPPTLLGVGVRTAQRSGGGVIIQDVLRGGPAEAAGLVP  287

Query  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            GD++ +++G  +++A  +   L+ H+PGDV+ +TW+ + G  R G  TLA GP
Sbjct  288  GDILMSIEGTLLDTARTLTLVLDQHYPGDVVDLTWRDRGGFDRNGKATLAAGP  340


>gi|108801875|ref|YP_642072.1| peptidase S1 and S6, chymotrypsin/Hap [Mycobacterium sp. MCS]
 gi|119871028|ref|YP_940980.1| peptidase S1 and S6, chymotrypsin/Hap [Mycobacterium sp. KMS]
 gi|108772294|gb|ABG11016.1| peptidase S1 and S6, chymotrypsin/Hap [Mycobacterium sp. MCS]
 gi|119697117|gb|ABL94190.1| peptidase S1 and S6, chymotrypsin/Hap [Mycobacterium sp. KMS]
Length=341

 Score =  257 bits (657),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 149/299 (50%), Positives = 197/299 (66%), Gaps = 6/299 (2%)

Query  59   VGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDV  118
            V P V  I+T++ Y +A+G GTGIV+DP G VLTN HV+ GA  +N     +G++Y  ++
Sbjct  45   VEPAVARIDTEIDYQSAIGTGTGIVLDPGGQVLTNFHVVQGADRVNVAV--AGRSYPAEL  102

Query  119  VGYDRTQDVAVLQLRGAGGLPSAAIG--GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVAL  176
            VGYDR +D+AV+QL GAGGLP A IG    +A GEPVVA+GN+ G         G V A 
Sbjct  103  VGYDRGRDIAVIQLLGAGGLPVAPIGDSAALAAGEPVVALGNAQGSAAPLTREVGSVTAF  162

Query  177  GQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGG  236
            G+TVQA DSLTG+ + L GLI+F A ++ GDSGGPVVN  GQVVG+ TAAS N+++  GG
Sbjct  163  GRTVQAEDSLTGSSDELTGLIEFAAPVRAGDSGGPVVNSAGQVVGITTAASVNYRMGPGG  222

Query  237  QGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV--VDNNGNGARVQRVVGSAPAA  294
            +GFAIPI +A+ +A QIRS   S TVHIGP A LG+GV    ++  G  +Q V+   PA 
Sbjct  223  KGFAIPINEAVGVANQIRSRIPSDTVHIGPPALLGVGVRTAPSDVPGVLIQEVLRGGPAE  282

Query  295  SLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            + G+   DV+ A++G  + SAT +   L+  +PGDV+ VTW    G  RT   TLA GP
Sbjct  283  AAGLMDRDVLIAINGNRLTSATQLTYTLDRFYPGDVVDVTWIDGFGQERTAKATLAPGP  341


>gi|126437843|ref|YP_001073534.1| peptidase S1 and S6, chymotrypsin/Hap [Mycobacterium sp. JLS]
 gi|126237643|gb|ABO01044.1| peptidase S1 and S6, chymotrypsin/Hap [Mycobacterium sp. JLS]
Length=341

 Score =  256 bits (655),  Expect = 3e-66, Method: Compositional matrix adjust.
 Identities = 149/299 (50%), Positives = 197/299 (66%), Gaps = 6/299 (2%)

Query  59   VGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDV  118
            V P V  I+T++ Y +A+G GTGIV+DP G VLTN HV+ GA  +N     +G++Y  ++
Sbjct  45   VEPAVARIDTEIDYQSAIGTGTGIVLDPGGQVLTNFHVVQGADRVNVTV--AGRSYPAEL  102

Query  119  VGYDRTQDVAVLQLRGAGGLPSAAIG--GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVAL  176
            VGYDR +D+AV+QL GAGGLP A IG    +A GEPVVA+GN+ G         G V A 
Sbjct  103  VGYDRGRDIAVIQLLGAGGLPVAPIGDSAALAAGEPVVALGNAQGSAAPLTREVGSVTAF  162

Query  177  GQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGG  236
            G+TVQA DSLTG+ + L GLI+F A ++ GDSGGPVVN  GQVVG+ TAAS N+++  GG
Sbjct  163  GRTVQAEDSLTGSSDELTGLIEFAAPVRAGDSGGPVVNSAGQVVGITTAASVNYRMGPGG  222

Query  237  QGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV--VDNNGNGARVQRVVGSAPAA  294
            +GFAIPI +A+ +A QIRS   S TVHIGP A LG+GV    ++  G  +Q V+   PA 
Sbjct  223  KGFAIPINEAVGVANQIRSRIPSDTVHIGPPALLGVGVRTAPSDVPGVLIQEVLRGGPAE  282

Query  295  SLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            + G+   DV+ A++G  + SAT +   L+  +PGDV+ VTW    G  RT   TLA GP
Sbjct  283  AAGLMDRDVLIAINGNRLTSATQLTYTLDRFYPGDVVDVTWIDGFGQERTAKATLAPGP  341


>gi|315446395|ref|YP_004079274.1| trypsin-like serine protease with C-terminal PDZ domain [Mycobacterium 
sp. Spyr1]
 gi|315264698|gb|ADU01440.1| trypsin-like serine protease with C-terminal PDZ domain [Mycobacterium 
sp. Spyr1]
Length=339

 Score =  254 bits (649),  Expect = 1e-65, Method: Compositional matrix adjust.
 Identities = 147/296 (50%), Positives = 192/296 (65%), Gaps = 6/296 (2%)

Query  58   QVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVD  117
            QV P VV I+T + Y   +G GTG+VIDP G+VLTN HV+ GA  I A +VG G+ Y   
Sbjct  42   QVEPAVVRIDTAVDYQGVIGLGTGMVIDPGGLVLTNFHVVQGADRITA-TVG-GRPYPAQ  99

Query  118  VVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQGGTPRAVPGRVVA  175
            +VGYDR +DVAV+QL GA GLP+A IG    +A GEPVVA+GN+ G         G + A
Sbjct  100  LVGYDRGRDVAVIQLLGAAGLPAAPIGDANILAPGEPVVALGNAMGSDAPLTREVGTLTA  159

Query  176  LGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQG  235
             G+TV+A D+LTG+ + L GL +F A ++ GDSGGPVV+  GQVVG+ TAAS NF++  G
Sbjct  160  FGRTVEAEDTLTGSTDELTGLFEFAAPVRAGDSGGPVVSSTGQVVGVTTAASVNFRMGPG  219

Query  236  GQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV--VDNNGNGARVQRVVGSAPA  293
            G+GFAIPI  AM + GQIR+G  S TVHIGP   LG+GV     +  G  +Q V+   PA
Sbjct  220  GKGFAIPINDAMGVVGQIRAGVPSDTVHIGPPTLLGVGVRAAPRDAPGVLIQEVMVGGPA  279

Query  294  ASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTL  349
               G+  GD+I  +DG P++S   +   L+ H+PGDV+ +TW    G TRTG   L
Sbjct  280  DRAGLLAGDIIVMLDGTPLDSTNTLTSVLDRHYPGDVLDLTWIDTLGQTRTGKAVL  335


>gi|339293189|gb|AEJ45300.1| serine protease pepA [Mycobacterium tuberculosis CCDC5079]
Length=137

 Score =  252 bits (644),  Expect = 5e-65, Method: Compositional matrix adjust.
 Identities = 131/132 (99%), Positives = 132/132 (100%), Gaps = 0/132 (0%)

Query  14   LLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYN  73
            +LSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYN
Sbjct  1    MLSVLAAVGLGLATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYN  60

Query  74   NAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLR  133
            NAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLR
Sbjct  61   NAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLR  120

Query  134  GAGGLPSAAIGG  145
            GAGGLPSAAIGG
Sbjct  121  GAGGLPSAAIGG  132


>gi|120406480|ref|YP_956309.1| PDZ/DHR/GLGF domain-containing protein [Mycobacterium vanbaalenii 
PYR-1]
 gi|119959298|gb|ABM16303.1| PDZ/DHR/GLGF domain protein [Mycobacterium vanbaalenii PYR-1]
Length=335

 Score =  252 bits (644),  Expect = 6e-65, Method: Compositional matrix adjust.
 Identities = 148/307 (49%), Positives = 191/307 (63%), Gaps = 6/307 (1%)

Query  47   ALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAF  106
            A P DP A   QV P VV I+T++ Y   VG GTGIV+DP G VLTN HV+ GA  I   
Sbjct  27   AAPGDPVAASVQVEPAVVRIDTEVDYQGVVGLGTGIVLDPAGQVLTNFHVVQGADRITGT  86

Query  107  SVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAV--GEPVVAMGNSGGQGG  164
               +G+ Y   +VGYDR +DVAVLQL GA GL +A IG   A+  G+PVVA+GN+ G   
Sbjct  87   V--AGRAYPAQLVGYDRKRDVAVLQLIGANGLAAAPIGDAYALVPGQPVVALGNAMGTEA  144

Query  165  TPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNT  224
                  G +   G+TVQA D+LTG  + L GL +F A ++ GDSGGPVVN LGQVVG+ T
Sbjct  145  PLTREVGTLTGFGRTVQAEDTLTGTSDELTGLFEFAAPVRAGDSGGPVVNDLGQVVGITT  204

Query  225  AASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV--VDNNGNGA  282
            AAS NF++  GG+GFAIPI  AM +AGQIR G  S +VHIGP   LG+GV     +  G 
Sbjct  205  AASVNFRMGPGGKGFAIPINDAMGVAGQIRGGIRSDSVHIGPPTLLGVGVRTAPRDEPGV  264

Query  283  RVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGT  342
             +Q V+   PA   G+  GD++  +DG P++S   +   L+ H+ GDV+ +TW   +G T
Sbjct  265  LIQEVMVGGPADLAGLRAGDILIELDGTPLDSTNTLTSVLDRHYTGDVLDLTWVDSTGVT  324

Query  343  RTGNVTL  349
            R G   L
Sbjct  325  RDGKAVL  331


>gi|145221870|ref|YP_001132548.1| PDZ/DHR/GLGF domain-containing protein [Mycobacterium gilvum 
PYR-GCK]
 gi|145214356|gb|ABP43760.1| PDZ/DHR/GLGF domain protein [Mycobacterium gilvum PYR-GCK]
Length=297

 Score =  251 bits (641),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 145/293 (50%), Positives = 190/293 (65%), Gaps = 6/293 (2%)

Query  61   PQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVG  120
            P VV I+T + Y   +G GTG+VIDP G+VLTN HV+ GA  I A +VG G+ Y   +VG
Sbjct  3    PAVVRIDTAVDYQGVIGLGTGMVIDPGGLVLTNFHVVQGADRITA-TVG-GRPYPAQLVG  60

Query  121  YDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQ  178
            YDR +DVAV+QL GA GLP+A IG    +A GEPVVA+GN+ G         G + A G+
Sbjct  61   YDRGRDVAVIQLLGAAGLPAAPIGDANILAPGEPVVALGNAMGSDAPLTREVGTLTAFGR  120

Query  179  TVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQG  238
            TV+A D+LTG+ + L GL +F A ++ GDSGGPVV+  GQVVG+ TAAS NF++  GG+G
Sbjct  121  TVEAEDTLTGSTDELTGLFEFAAPVRAGDSGGPVVSSTGQVVGVTTAASVNFRMGPGGKG  180

Query  239  FAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV--VDNNGNGARVQRVVGSAPAASL  296
            FAIPI  AM + GQIR+G  S TVHIGP   LG+GV     +  G  +Q V+   PA   
Sbjct  181  FAIPINDAMGVVGQIRAGVPSDTVHIGPPTLLGVGVRAAPRDAPGVLIQEVMVGGPADRA  240

Query  297  GISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTL  349
            G+  GD+I  +DG P++S   +   L+ H+PGDV+ +TW    G TRTG   L
Sbjct  241  GLLAGDIIVMLDGTPLDSTNTLTSVLDRHYPGDVLDLTWIDTLGQTRTGKAVL  293


>gi|111021065|ref|YP_704037.1| serine protease [Rhodococcus jostii RHA1]
 gi|110820595|gb|ABG95879.1| probable serine protease [Rhodococcus jostii RHA1]
Length=358

 Score =  236 bits (602),  Expect = 4e-60, Method: Compositional matrix adjust.
 Identities = 138/304 (46%), Positives = 191/304 (63%), Gaps = 10/304 (3%)

Query  57   AQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGV  116
            A+V P +V +    G      AGTGIV+ P+GVVLTN+HVI GA DI+A S+G+G  Y  
Sbjct  58   ARVIPAIVTLVADSGLVET--AGTGIVLTPDGVVLTNHHVIDGALDISAVSLGNGTAYVA  115

Query  117  DVVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQGGTPRAVPGRVV  174
            DV+GYD ++DVAVL+LRGAG LP A +     + +G+PV A+GN+ G GG P A  G V 
Sbjct  116  DVLGYDSSRDVAVLRLRGAGDLPVATLSKDTTIGIGDPVTAVGNAEG-GGVPVAARGFVT  174

Query  175  ALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQ  234
             + QT+ A  S  G+   LNGLIQ DAA++PGDSGGP+V+    V+G+NTA + +   ++
Sbjct  175  DVEQTITARSSTDGSRNRLNGLIQIDAAVRPGDSGGPLVDATAAVIGVNTAGNADSDPTK  234

Query  235  GG----QGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGS  290
                  + +A+PI  AM I  Q+R+G  S TVHIG T  LG+ V D++  GA V  V   
Sbjct  235  PAPAQPRSYAVPIDTAMTIVDQVRAGTTSATVHIGDTPLLGISVTDDD-RGAEVLWVSIG  293

Query  291  APAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLA  350
             PA   GI  GDVIT  DG P+ S+  +++ + G HPGD ++V W  ++G  R+  + L 
Sbjct  294  TPADEAGIEIGDVITDFDGTPVRSSDDLSERMIGRHPGDEVAVRWFDETGQQRSTTIVLE  353

Query  351  EGPP  354
            +GPP
Sbjct  354  KGPP  357


>gi|226363367|ref|YP_002781149.1| S1C family peptidase [Rhodococcus opacus B4]
 gi|226241856|dbj|BAH52204.1| putative S1C family peptidase [Rhodococcus opacus B4]
Length=358

 Score =  235 bits (599),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 138/304 (46%), Positives = 189/304 (63%), Gaps = 10/304 (3%)

Query  57   AQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGV  116
            A+V P +V +    G      AGTGIV+ P+GVVLTN+HVI GA DI+A S+G+G  Y  
Sbjct  58   ARVIPAIVTLVADSGLVET--AGTGIVLTPDGVVLTNHHVIDGAIDISAVSLGNGAEYVA  115

Query  117  DVVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQGGTPRAVPGRVV  174
            DV+GYD ++D+AVL+L+GAG LP+A +     VAVG+PV A+GN+ G GG P A  G V 
Sbjct  116  DVLGYDSSRDIAVLRLQGAGDLPAATLAKDTTVAVGDPVTAVGNAEG-GGVPVAARGFVT  174

Query  175  ALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQ  234
             LGQ + A  S  G+   LNGLIQ DAA++PGDSGGP+V+    V+G+NTA + +   ++
Sbjct  175  DLGQAITARSSTDGSRNRLNGLIQIDAAVRPGDSGGPLVDATAAVIGVNTAGNADSDPTK  234

Query  235  GG----QGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVVGS  290
                  + +A+PI  AM I  Q+R+G  S TVHIG T  LG+ V D +  GA V  V   
Sbjct  235  PAPAQPRSYAVPIDTAMTIVDQVRAGAASATVHIGDTPLLGISVTD-DARGAEVLWVSIG  293

Query  291  APAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLA  350
             PA   GI  GDV+T  DG PI S+  ++  +   HPGD + + W  ++G  R+  + L 
Sbjct  294  TPADDAGIEIGDVVTEFDGIPIRSSDDLSGLMISRHPGDAVDMRWLDETGRQRSTTIVLE  353

Query  351  EGPP  354
            +GPP
Sbjct  354  KGPP  357


>gi|148273618|ref|YP_001223179.1| secreted serine protease [Clavibacter michiganensis subsp. michiganensis 
NCPPB 382]
 gi|147831548|emb|CAN02515.1| putative secreted serine protease, family S1C [Clavibacter michiganensis 
subsp. michiganensis NCPPB 382]
Length=394

 Score =  233 bits (593),  Expect = 5e-59, Method: Compositional matrix adjust.
 Identities = 150/306 (50%), Positives = 195/306 (64%), Gaps = 10/306 (3%)

Query  52   PSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSG  111
            P A  AQ    VV I++ L Y NA GAGTGI++  +G +LTNNHV++GAT I      +G
Sbjct  93   PEATTAQK-AGVVTIDSALTYENAAGAGTGIILSSDGTILTNNHVVSGATSIRVTVESTG  151

Query  112  QTYGVDVVGYDRTQDVAVLQLRGAGGL-PSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVP  170
            + Y   VVG D T DVAVL+L  A GL P+     GV VGE V  +GN+GG  GT  A  
Sbjct  152  KAYVGKVVGTDATNDVAVLKLEDASGLTPAKLDTDGVQVGEAVTGVGNAGGT-GTLTAAT  210

Query  171  GRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASD-N  229
            G+V ALGQT+      T A ETL  LIQ DAAI  GDSGGP+V+  G+VVG++TAAS  +
Sbjct  211  GQVTALGQTITTQSEGTAAGETLTDLIQTDAAIVSGDSGGPLVDAEGEVVGIDTAASSGS  270

Query  230  FQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGN--GARVQRV  287
             Q++    GFAIPI +A++IA QI SG  S TV IG  AFLG+ + D  G   GA VQ V
Sbjct  271  AQIA----GFAIPIDKAVSIATQIESGVESGTVKIGYPAFLGVLLADGAGTVAGAPVQGV  326

Query  288  VGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNV  347
            V  + AA  G++ GDV+T+VDG  + SA+ ++ A++ H PG+ + + W T +G  +TG V
Sbjct  327  VDGSGAAKAGLAQGDVVTSVDGKAVASASELSAAISAHKPGESVELGWTTAAGAEKTGTV  386

Query  348  TLAEGP  353
            TL EGP
Sbjct  387  TLTEGP  392


>gi|302527941|ref|ZP_07280283.1| predicted protein [Streptomyces sp. AA4]
 gi|302436836|gb|EFL08652.1| predicted protein [Streptomyces sp. AA4]
Length=474

 Score =  228 bits (582),  Expect = 9e-58, Method: Compositional matrix adjust.
 Identities = 160/353 (46%), Positives = 209/353 (60%), Gaps = 49/353 (13%)

Query  50   LDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVG  109
            LDP A+  +V   +VNINT+LGY  A  AGTGIV+ P+G VLTNNHV+ GAT I    +G
Sbjct  120  LDPQAIAKKVSAGIVNINTELGYQGAAAAGTGIVLTPDGEVLTNNHVVEGATSIKVTDIG  179

Query  110  SGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIG--GGVAVGEPVVAMGNSGGQGGTPR  167
            +GQTY   V+GYDR+ DVAVL+L  A GL +  +G    V VG+ VV +GN+GG GG P 
Sbjct  180  NGQTYPASVLGYDRSHDVAVLKLAAASGLATETLGDSSSVKVGDAVVGLGNAGGAGGAPI  239

Query  168  AVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAAS  227
               GRV AL Q++ ASD    + E L  LIQ DA IQ GDSGGP+VN  GQVVG++TAAS
Sbjct  240  PAGGRVTALNQSITASDESNSSSEQLKDLIQVDANIQSGDSGGPLVNAQGQVVGVDTAAS  299

Query  228  DNFQLSQGG-----------------------------------------QGFAIPIGQA  246
              +Q + GG                                         +G+AIPI QA
Sbjct  300  AGYQFNGGGRRGHSGLGNGFPGDNSQGGSQGDGSQGNGSQGNGSQGSGGHEGYAIPINQA  359

Query  247  MAIAGQIRSGGGSPTVHIGPTAFLGLGVVD------NNGNGARVQRVVGSAPAASLGIST  300
            +++A QI  G GS TVHIG +AFLG+ V D        G+GA +Q+VV    AA  G++ 
Sbjct  360  ISLAHQIVGGTGSDTVHIGKSAFLGVTVSDAGQQQGGTGSGAAIQQVVPDGAAAQAGLAA  419

Query  301  GDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            GDVITAVDG  ++S TA+   ++ HHPGD ++VT+  ++G  +   V  A+GP
Sbjct  420  GDVITAVDGKAVDSPTALTALMDQHHPGDKLTVTFLDQTGQQQNATVVPADGP  472


>gi|229492648|ref|ZP_04386451.1| trypsin [Rhodococcus erythropolis SK121]
 gi|229320634|gb|EEN86452.1| trypsin [Rhodococcus erythropolis SK121]
Length=363

 Score =  220 bits (561),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 133/316 (43%), Positives = 190/316 (61%), Gaps = 10/316 (3%)

Query  46   PALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINA  105
            P +PL P  + A+V P +V I    G+     AGTGIV+ P+GVVLTN+HVI+GA+D+ A
Sbjct  50   PVVPLTPEELSARVVPTIVTITAPAGFTTT--AGTGIVLSPDGVVLTNHHVISGASDVTA  107

Query  106  FSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQG  163
             S+ +G  Y  +++GYD   D+AVL+L GA  LP A +G     A G+ V A+GN+ G G
Sbjct  108  VSMSNGLIYDAEILGYDSVSDLAVLRLAGADDLPVAVVGKSAEAARGDSVTAIGNAEG-G  166

Query  164  GTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMN  223
            G P   PG +  LG TV   +   G+   L GLI+ DA I+PGDSGGP+VN +G+++G++
Sbjct  167  GVPVPAPGVITNLGVTVNTRNVSDGSRNQLKGLIEVDADIRPGDSGGPLVNAVGELIGVS  226

Query  224  T---AASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGN  280
            +   A +D  + S   Q +AIPI  A+ I  Q+  G  S TV +GPT  LG+ V D+   
Sbjct  227  SAGNAVTDRTETSPAPQSYAIPIDTALPIVEQVLGGRSSETVRVGPTPVLGVAVKDHADM  286

Query  281  --GARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTK  338
              GA V  V   +PA  +G++ G VIT   G+ I S+  +  A++   PGD ++VTW   
Sbjct  287  PAGAEVVAVSFDSPAERVGLTKGAVITEFGGSRIASSADLNAAMSSRRPGDTVAVTWVDA  346

Query  339  SGGTRTGNVTLAEGPP  354
            +G   TG++ L EGPP
Sbjct  347  TGQPGTGSLVLDEGPP  362


>gi|226303734|ref|YP_002763692.1| S1 family peptidase [Rhodococcus erythropolis PR4]
 gi|226182849|dbj|BAH30953.1| putative S1 family peptidase [Rhodococcus erythropolis PR4]
Length=364

 Score =  214 bits (546),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 131/312 (42%), Positives = 186/312 (60%), Gaps = 10/312 (3%)

Query  50   LDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVG  109
            L P  + AQV P +V I    G+     AGTGIV+ P+GVVLTN+HVI+GA+D+ A S+ 
Sbjct  55   LTPEELSAQVVPTIVTITAPAGFTTT--AGTGIVLSPDGVVLTNHHVISGASDVTAVSMS  112

Query  110  SGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAV--GEPVVAMGNSGGQGGTPR  167
            +G  Y  +++GYD   D+AVL+L GA  LP A +G       G+ V A+GN+ G GG P 
Sbjct  113  NGLIYDAEILGYDSVSDLAVLRLAGATDLPVAVVGKSAEATRGDAVTAIGNAEG-GGVPV  171

Query  168  AVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNT---  224
              PG +  LG TV   +   G+   L GLI+ DA I+PGDSGGP+VN +G+++G+++   
Sbjct  172  PAPGVITNLGVTVNTRNVSDGSRNQLKGLIEVDADIRPGDSGGPLVNAVGELIGVSSAGN  231

Query  225  AASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGN--GA  282
            A +D  + S   Q +AIPI  A+ I  Q+  G  S TV +GPT  LG+ V D+     GA
Sbjct  232  AVTDRTETSPAPQSYAIPIDTALPIVEQVLGGRSSETVRVGPTPVLGVAVKDHAEMPAGA  291

Query  283  RVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGT  342
             V  V   +PA  +G++ G VIT   G+ I S+  +  A++   PGD ++VTW   +G  
Sbjct  292  EVVAVSFDSPAERVGLTKGAVITEFGGSRIASSADLNAAMSSRRPGDTVAVTWVDATGQP  351

Query  343  RTGNVTLAEGPP  354
             TG++ L EGPP
Sbjct  352  GTGSLVLDEGPP  363


>gi|170782706|ref|YP_001711040.1| putative protease [Clavibacter michiganensis subsp. sepedonicus]
 gi|169157276|emb|CAQ02461.1| putative protease [Clavibacter michiganensis subsp. sepedonicus]
Length=392

 Score =  214 bits (544),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 143/295 (49%), Positives = 189/295 (65%), Gaps = 9/295 (3%)

Query  63   VVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYD  122
            VV I++ L Y NA GAGTGI++  +G +LTNNHV++GAT I      +G+ Y   VVG D
Sbjct  101  VVTIDSALTYENAAGAGTGIILSSDGTILTNNHVVSGATSIRVTVESTGKAYVGKVVGTD  160

Query  123  RTQDVAVLQLRGAGGL-PSAAIGGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQ  181
             T DVAVL+L GA GL P+     GV VGE V  +GN+GG  GT  A  G+V A GQ++ 
Sbjct  161  ATNDVAVLKLEGASGLTPAKLDSDGVQVGEAVTGVGNAGGT-GTLTAATGQVTATGQSIT  219

Query  182  ASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASD-NFQLSQGGQGFA  240
                 T A ETL  LIQ DA I  GDSGGP+V+   +VVG++TAAS  + Q++    GFA
Sbjct  220  TQSEGTAAGETLTDLIQTDAPIVSGDSGGPLVDTENEVVGIDTAASSGSAQIA----GFA  275

Query  241  IPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGN--GARVQRVVGSAPAASLGI  298
            IPI +AM IA QI SG  S TV IG  AFLG+ + +  G   GA VQ VV  + AA  G+
Sbjct  276  IPIEKAMGIAKQIESGVESGTVKIGYPAFLGVLLANGQGTVAGAPVQGVVDGSGAAKAGL  335

Query  299  STGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            + GDV+T+VDG  + SA+ ++ A++ H PG+ +++ W T +G  +TG VTL EGP
Sbjct  336  AQGDVVTSVDGKAVASASELSAAISAHKPGESVTLGWTTAAGAAKTGAVTLTEGP  390


>gi|325675110|ref|ZP_08154796.1| serine protease [Rhodococcus equi ATCC 33707]
 gi|325554071|gb|EGD23747.1| serine protease [Rhodococcus equi ATCC 33707]
Length=372

 Score =  198 bits (504),  Expect = 1e-48, Method: Compositional matrix adjust.
 Identities = 117/280 (42%), Positives = 172/280 (62%), Gaps = 12/280 (4%)

Query  86   PNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGG  145
            P  +VLTN+HVI G TDI A S+  G  Y V+V+GYD ++D+AVL+L G   LP AA+G 
Sbjct  93   PAAIVLTNHHVIDGGTDITAESMRDGTPYPVEVLGYDSSRDLAVLRLPGGAALPPAALGS  152

Query  146  G--VAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAI  203
                 VG+PV A+GN+ G GG P++ PG V  LG TV   +S+ G+   L GLI+ +A +
Sbjct  153  SRNAGVGDPVTAIGNAEG-GGVPQSAPGAVTRLGVTVLTRNSVDGSRNELAGLIEVNADV  211

Query  204  QPGDSGGPVVNGLGQVVGMNT---AASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSP  260
            +PGDSGGP+V+  G+V+G+++   A   +   +   + +AIPI  A+ +  QI +G  S 
Sbjct  212  RPGDSGGPLVDAFGEVIGVSSAGNAVQRDEPSAPAPKSYAIPIDSALEVVDQILAGRPSD  271

Query  261  TVHIGPTAFLGLGVVDN------NGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINS  314
            +VHIGPT  LG+ V D+         GA++ +V   +PA  LG++ GDVI    G PI +
Sbjct  272  SVHIGPTPQLGVSVRDHVEPQAGTPAGAQIVQVSYRSPADGLGLARGDVIVQFGGVPIRT  331

Query  315  ATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPP  354
            A+ +   +   HPGDV+ + W   +G  R+G++ L EGPP
Sbjct  332  ASDLTVRMIALHPGDVVDLAWIDATGAQRSGSMVLTEGPP  371


>gi|312137738|ref|YP_004005074.1| serine peptidase [Rhodococcus equi 103S]
 gi|311887077|emb|CBH46386.1| putative secreted serine peptidase [Rhodococcus equi 103S]
Length=372

 Score =  198 bits (503),  Expect = 1e-48, Method: Compositional matrix adjust.
 Identities = 118/280 (43%), Positives = 172/280 (62%), Gaps = 12/280 (4%)

Query  86   PNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGG  145
            P  +VLTN+HVI G TDI A S+  G  Y V+V+GYD ++D+AVL+L G   LP AA+G 
Sbjct  93   PAAIVLTNHHVIDGGTDITAESMRDGTPYPVEVLGYDSSRDLAVLRLPGGAALPPAALGS  152

Query  146  G--VAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAI  203
                 VG+PV A+GN+ G GG P++ PG V  LG TV   +S+ G+   L GLI+ +A +
Sbjct  153  SRNAGVGDPVTAIGNAEG-GGVPQSAPGAVTRLGVTVLTRNSVDGSRNELAGLIEVNADV  211

Query  204  QPGDSGGPVVNGLGQVVGMNT---AASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSP  260
            +PGDSGGP+V+  G+V+G+++   A   +   +   + +AIPI  A+ +  QI +G  S 
Sbjct  212  RPGDSGGPLVDAFGEVIGVSSAGNAVQRDEPSAPAPKSYAIPIDSALEVVDQILAGRPSD  271

Query  261  TVHIGPTAFLGLGVVDN------NGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINS  314
            +VHIGPT  LG+ V D+         GA++ +V   +PA  LG++ GDVI    G PI +
Sbjct  272  SVHIGPTPQLGVSVRDHVEPQAGTPAGAQIVQVSYRSPADGLGLARGDVIVQFGGVPIRT  331

Query  315  ATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPP  354
            A+ +   +   HPGDV+ V W   +G  R+G++ L EGPP
Sbjct  332  ASDLTVRMIALHPGDVVDVGWIDATGAQRSGSMVLTEGPP  371


>gi|54027199|ref|YP_121441.1| putative protease [Nocardia farcinica IFM 10152]
 gi|54018707|dbj|BAD60077.1| putative protease [Nocardia farcinica IFM 10152]
Length=364

 Score =  194 bits (493),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 125/312 (41%), Positives = 184/312 (59%), Gaps = 3/312 (0%)

Query  46   PALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINA  105
            P  PLD +A+ A+V P +VNI+T+        AGTGIV+  +G VLT++HV+ GA  +  
Sbjct  52   PNPPLDQAAVAAEVTPALVNISTRTRPLGQGAAGTGIVLTADGQVLTSHHVVKGAEQVVV  111

Query  106  FSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQG  163
             +  +G  Y   V+GYD T D+A+L L GA GLP+A +G    V V + V+A+GN+GG G
Sbjct  112  TTQATGAEYRATVLGYDSTADIALLSLPGANGLPTARLGSSSSVRVRDEVLALGNAGGTG  171

Query  164  GTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMN  223
            G P A PG V AL  T+ A ++   + + L G+++  A +  G SGG +V+  G VVG+ 
Sbjct  172  GPPTATPGLVTALNSTIVALNAADLSRKALRGMVEVAAPVSSGQSGGALVDWQGAVVGVV  231

Query  224  TAASDNFQLS-QGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGA  282
            TA+S       +   G+A+PI  AM +  QIRSG  + TVHIGPTA LG+ + D + +GA
Sbjct  232  TASSGEAAAELERPNGYAVPIDTAMRVVRQIRSGIPTDTVHIGPTATLGVLISDASPSGA  291

Query  283  RVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGT  342
            R+   +   PA + G++ G+VI ++DG PI SA  +  A++   PG+ + +      G  
Sbjct  292  RIDVALYGLPAYAAGLADGEVIVSIDGRPIGSARVLRTAIDRRRPGETVRLGVLGVDGVE  351

Query  343  RTGNVTLAEGPP  354
            RT  V L  G P
Sbjct  352  RTVTVELGLGTP  363


>gi|332671091|ref|YP_004454099.1| PDZ/DHR/GLGF domain-containing protein [Cellulomonas fimi ATCC 
484]
 gi|332340129|gb|AEE46712.1| PDZ/DHR/GLGF domain protein [Cellulomonas fimi ATCC 484]
Length=544

 Score =  190 bits (482),  Expect = 4e-46, Method: Compositional matrix adjust.
 Identities = 134/299 (45%), Positives = 184/299 (62%), Gaps = 15/299 (5%)

Query  63   VVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYD  122
            VV I + LGY     AGTG+V+   G+VLTN+HV+ GAT I+     +G+T+   VVGYD
Sbjct  251  VVTITSTLGYQGGSSAGTGMVLTTGGLVLTNHHVVEGATAISVTVESTGETFEATVVGYD  310

Query  123  RTQDVAVLQLRGAGGLPSAAI--GGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTV  180
             + DVA+LQL GA GL +  +   GGVA G+ V A+GN+ G G    A  G V    +T+
Sbjct  311  ASADVALLQLTGASGLATVTLDDDGGVAPGDTVTAVGNADGTGEL-VAATGEVTGTDETM  369

Query  181  QASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ---  237
             A  S  G  ETL+GL++F AA+  GDSGGPV++  G+VVG+ TAA      S GG    
Sbjct  370  TARTSTAGEAETLSGLLEFSAAVVGGDSGGPVLDEEGEVVGITTAA------SVGGTSTV  423

Query  238  GFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNG--NGARVQRVVGSAPAAS  295
             +AI +  A+A+  QI SG  + TV IG  AFLG+G+    G   GARV  V+   PAA 
Sbjct  424  AYAIDVVDAVAVLQQISSGEETATVRIGYPAFLGIGLDAGAGTVTGARVAGVLDGTPAAG  483

Query  296  LGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGG-TRTGNVTLAEGP  353
             G++ GDV+TAVDG  ++SATA+ + L+G+ PGD +++TW   + G +    VTL +GP
Sbjct  484  AGLAAGDVVTAVDGTAVSSATALQELLDGYAPGDAVTLTWTDAATGVSEQAAVTLTQGP  542


>gi|258654784|ref|YP_003203940.1| peptidase S1 and S6 chymotrypsin/Hap [Nakamurella multipartita 
DSM 44233]
 gi|258558009|gb|ACV80951.1| peptidase S1 and S6 chymotrypsin/Hap [Nakamurella multipartita 
DSM 44233]
Length=423

 Score =  186 bits (473),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 142/317 (45%), Positives = 181/317 (58%), Gaps = 23/317 (7%)

Query  58   QVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVD  117
            QVG  +V I+T LGY +A  AGTG+V+  NG +LTNNHVI G+T I    V +GQTY   
Sbjct  111  QVG--LVYIDTVLGYQDAAAAGTGLVLTSNGQILTNNHVIEGSTSITVTIVTTGQTYQAS  168

Query  118  VVGYDRTQDVAVLQLRGAGGLPSAAIG--GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVA  175
            VVG D   D+AVLQL  A GL +A  G    + VGE VV +GN+GG GGTP A  G V A
Sbjct  169  VVGTDVQDDIAVLQLGDASGLTTANFGTSADLQVGESVVGVGNAGGDGGTPSAAAGVVSA  228

Query  176  LGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQG  235
            L QT+      + A ETL GLI+  A IQ GDSGGP+ +   +VVG++TAA       Q 
Sbjct  229  LNQTITTQAEGSAAGETLTGLIETTADIQSGDSGGPLFDANDEVVGIDTAA--EVVAGQS  286

Query  236  GQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGV-----------------VDNN  278
              G+AIPI  A+ IA QI +G  S  V IG  AFLG+ V                     
Sbjct  287  ENGYAIPIDTALGIAKQIITGDESDGVRIGYPAFLGVQVQSAATAGTGTGRSRSGSSSTG  346

Query  279  GNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTK  338
              GA +  VV  +PA   G++ GD +T +D   ++SA  ++ AL  H+PGD +SVTW   
Sbjct  347  TAGALIGGVVSGSPAEQAGLTAGDTVTGIDDRAVSSADGLSTALAAHNPGDRVSVTWVDS  406

Query  339  SGGTRTGNVTLAEGPPA  355
            SG   +  VTLA+GP A
Sbjct  407  SGAKHSATVTLAQGPAA  423


>gi|331696262|ref|YP_004332501.1| PDZ/DHR/GLGF domain-containing protein [Pseudonocardia dioxanivorans 
CB1190]
 gi|326950951|gb|AEA24648.1| PDZ/DHR/GLGF domain protein [Pseudonocardia dioxanivorans CB1190]
Length=433

 Score =  179 bits (453),  Expect = 9e-43, Method: Compositional matrix adjust.
 Identities = 149/325 (46%), Positives = 185/325 (57%), Gaps = 24/325 (7%)

Query  54   AMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQT  113
            A  AQ    VV+I+T L Y     AGTG+V+  +G VLTNNHV+A AT I    VG+G +
Sbjct  110  AATAQEEVGVVDIDTVLDYGTGRAAGTGLVLTADGEVLTNNHVVADATSITVTVVGTGAS  169

Query  114  YGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAV-----GEPVVAMGNSGGQGGTPRA  168
            Y   VVG D T DVAVL+L  A GL  A +           G  V A+GN+GG GGTP A
Sbjct  170  YRASVVGTDATDDVAVLRLADASGLTPAVLASSAQQAAVAPGTAVTAVGNAGGVGGTPSA  229

Query  169  VPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASD  228
             PG V+AL Q + A D   G  E L G+I+ DAAI+ GDSGGP+  G G VVG++TAAS 
Sbjct  230  APGTVLALDQAITAGDESGGDSEQLTGMIEVDAAIEAGDSGGPLYAG-GAVVGIDTAASS  288

Query  229  -----NFQL------SQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGL-----  272
                 +F+       S G  GFAIPIG A+ IA QI SG  S  +  G  AFLG+     
Sbjct  289  ASSGPSFRTAALPGSSSGTVGFAIPIGTALDIAQQITSGEQSDAITQGTPAFLGVELAQG  348

Query  273  --GVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDV  330
              GV D    GA V  VV   PAA+ G++ GDV+T+V   P++   A++ AL  H PGD 
Sbjct  349  AGGVADPAAEGAVVSGVVPGGPAAAAGLAAGDVVTSVGATPVDGPDALSAALAAHRPGDH  408

Query  331  ISVTWQTKSGGTRTGNVTLAEGPPA  355
            + + W   SG  RT  VTLA GP A
Sbjct  409  VEIGWSDASGSARTATVTLAAGPAA  433


>gi|339293190|gb|AEJ45301.1| serine protease pepA [Mycobacterium tuberculosis CCDC5079]
Length=159

 Score =  178 bits (452),  Expect = 1e-42, Method: Compositional matrix adjust.
 Identities = 93/93 (100%), Positives = 93/93 (100%), Gaps = 0/93 (0%)

Query  145  GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQ  204
            GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQ
Sbjct  2    GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQ  61

Query  205  PGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ  237
            PGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ
Sbjct  62   PGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQ  94


>gi|336321368|ref|YP_004601336.1| PDZ/DHR/GLGF domain-containing protein [Cellvibrio gilvus ATCC 
13127]
 gi|336104949|gb|AEI12768.1| PDZ/DHR/GLGF domain protein [Cellvibrio gilvus ATCC 13127]
Length=463

 Score =  178 bits (451),  Expect = 1e-42, Method: Compositional matrix adjust.
 Identities = 136/304 (45%), Positives = 177/304 (59%), Gaps = 15/304 (4%)

Query  58   QVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVD  117
            QVG  VV I + LGY  A  AGTG+V+  +G+VLTNNHVI GAT+I      +G TY   
Sbjct  165  QVG--VVTITSTLGYAQAESAGTGMVLTADGLVLTNNHVIDGATEIEVTVESTGTTYAAT  222

Query  118  VVGYDRTQDVAVLQLRGAGGLPSAAI--GGGVAVGEPVVAMGNSGGQGGTPRAVPGRVVA  175
            VVG     DVA+LQL  A GL    I   GGV VG+ V A+GN+ G G    A  G V A
Sbjct  223  VVGTAPDSDVALLQLEDASGLTPVTIDDDGGVDVGDQVTAVGNAEGTGDL-VAAAGTVTA  281

Query  176  LGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQG  235
              QT+ AS   T + ETL+GL+Q  A +  GDSGGPV++  G+VVGM TAAS     +  
Sbjct  282  TEQTMTASTDGTDS-ETLSGLVQLQADVVSGDSGGPVLDDEGEVVGMTTAASSGGVTT--  338

Query  236  GQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVD-----NNGNGARVQRVVGS  290
               +AI +  A+ +  QIRSG  S  V IG  AFLG+ +        +  GA +  VV  
Sbjct  339  -VAYAIDVQDALVLVRQIRSGDDSGGVTIGYPAFLGVSLATGPSGAGSAAGATIAGVVAD  397

Query  291  APAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKS-GGTRTGNVTL  349
             PAA  G+  GD +TAVDG  ++S   ++  L G+ PGD +++TW + S GGT+T  VTL
Sbjct  398  TPAAEAGLEAGDTVTAVDGTAVSSGDELSSVLAGYAPGDEVTLTWTSGSTGGTQTATVTL  457

Query  350  AEGP  353
             +GP
Sbjct  458  VQGP  461


>gi|297625432|ref|YP_003687195.1| secreted serine protease, trypsin-like serine proteases [Propionibacterium 
freudenreichii subsp. shermanii CIRM-BIA1]
 gi|296921197|emb|CBL55746.1| secreted serine protease, trypsin-like serine proteases [Propionibacterium 
freudenreichii subsp. shermanii CIRM-BIA1]
Length=480

 Score =  177 bits (450),  Expect = 2e-42, Method: Compositional matrix adjust.
 Identities = 130/336 (39%), Positives = 182/336 (55%), Gaps = 18/336 (5%)

Query  26   ATAPAQAAPPALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVID  85
            AT PAQA+P   SQ   A         +A  AQ    VV I T+    +   AG+G+V+ 
Sbjct  153  ATQPAQASPSTSSQRAVAQS-----QTTASEAQ-SKGVVLITTQT--TSGAAAGSGMVLS  204

Query  86   PNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGG  145
             +G VLTN HV+  +T I A    + + Y   VVG D T DVA+L+L GA GL +  I  
Sbjct  205  SDGYVLTNYHVVETSTQITATVASTNKQYNATVVGRDATNDVALLKLDGASGLDTVTIDS  264

Query  146  G-VAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAE-ETLNGLIQFDAAI  203
              V  G+ V A+GNS GQG    A  G+VV+   ++   +  + ++ ETL  + +     
Sbjct  265  DTVNTGDQVTAVGNSSGQGYL-SAATGQVVSTSSSITVQNETSASQTETLTNVYETSTQA  323

Query  204  QPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQG-----FAIPIGQAMAIAGQIRSGGG  258
             PGDSGGP+ +   +V+G+ TA       S+ GQ      +AIPI +AM+I  QI SG  
Sbjct  324  VPGDSGGPMFDAENEVMGITTAGETQTN-SRTGQSSTVSSYAIPIARAMSIVKQIESGQS  382

Query  259  SPTVHIGPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAM  318
            S TV +GP A+LG+ V  +      + +VV   PAA+ G+S G VITAVDG  I+S   +
Sbjct  383  SGTVQVGPKAYLGVTVQSSQSGSVTISQVVSDGPAAAAGLSVGQVITAVDGTRIDSQATL  442

Query  319  ADALNGHHPGDVISVTWQT-KSGGTRTGNVTLAEGP  353
            +  L  H PGD +SVT  +   GGT+T ++TL   P
Sbjct  443  SSVLAQHKPGDKVSVTVSSGYGGGTQTASLTLGTSP  478


>gi|256371362|ref|YP_003109186.1| PDZ/DHR/GLGF domain-containing protein [Acidimicrobium ferrooxidans 
DSM 10331]
 gi|256007946|gb|ACU53513.1| PDZ/DHR/GLGF domain protein [Acidimicrobium ferrooxidans DSM 
10331]
Length=487

 Score =  174 bits (441),  Expect = 2e-41, Method: Compositional matrix adjust.
 Identities = 131/338 (39%), Positives = 185/338 (55%), Gaps = 36/338 (10%)

Query  50   LDPSAMVAQVGPQVVNINTKLGYNNAVG------AGTGIVIDPNGVVLTNNHVIAGATDI  103
            L+  A++A+V P VV+I      +N  G      AGTG++I  NG+VLTNNHV+AGA+++
Sbjct  154  LNIPAILAKVEPAVVDITATGTTSNGFGVSQFEDAGTGMIISSNGLVLTNNHVVAGASNV  213

Query  104  NAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVA--VGEPVVAMGNSGG  161
                 G   +    ++G D   DVA+LQ+ GA  LP+   G   A  VG+PVVA+GN+  
Sbjct  214  RVTLYGQSSSRPAKIIGTDPAHDVALLQIEGASNLPTVTFGDSSALVVGDPVVAIGNALA  273

Query  162  QGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVG  221
              GTP    G V AL +T+ A+DSL G  ET++G+IQ DA I  G+SGGP+V+  G VVG
Sbjct  274  LQGTPTVTQGIVSALNRTITATDSL-GTTETISGMIQTDAPISSGNSGGPLVDAQGDVVG  332

Query  222  MNTAA-SDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPT-----------AF  269
            MNTA  + + Q S    GFA  I   + I   I     +PT + G +           AF
Sbjct  333  MNTAVIASSGQTSAQNLGFAESINSVLPIVKTIEQ---NPTAYTGSSTSPSTTTAGSGAF  389

Query  270  LGLGV------------VDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATA  317
            LG+G+            +  +  G  V+ V   + AA+ GI  GDVITAVDG  + SA A
Sbjct  390  LGVGIQTLTPTLDSQLGLPTSQTGVLVEYVYPGSGAANAGIQPGDVITAVDGQAVTSANA  449

Query  318  MADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            +A A++   PG  I+++  T+SG  ++   TL   P A
Sbjct  450  LATAIHAKSPGQQITLSIVTQSGAQQSLTATLGTSPAA  487


>gi|309811136|ref|ZP_07704933.1| trypsin [Dermacoccus sp. Ellin185]
 gi|308434924|gb|EFP58759.1| trypsin [Dermacoccus sp. Ellin185]
Length=410

 Score =  169 bits (429),  Expect = 5e-40, Method: Compositional matrix adjust.
 Identities = 116/287 (41%), Positives = 169/287 (59%), Gaps = 16/287 (5%)

Query  78   AGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGG  137
            AG+G+V+  +G VLTN HV++G+T I   +V +G +Y   VVG+D + DVAVL+L GA  
Sbjct  123  AGSGMVLTADGTVLTNYHVVSGSTQIR-VTVPNGGSYTASVVGHDESHDVAVLKLSGAKN  181

Query  138  LPSAAIG-GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASD--SLTGAEETLN  194
            L +  +   GV   E V+A+G  GG+G    A  G V A G+++ AS+  SL+  E  L 
Sbjct  182  LDTVTLDTDGVRTAEEVLAVGQGGGEG-VLYAASGIVTATGRSITASEQGSLSSGEN-LT  239

Query  195  GLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLS----QGGQGFAIPIGQAMAIA  250
             L+Q DA I  G SGGP+ +  G+VVG++TAAS    L+       +G+AIPI QA +IA
Sbjct  240  NLVQTDAPIVGGYSGGPLFDAAGKVVGIDTAASATNSLTGYQRSNAEGYAIPITQAKSIA  299

Query  251  GQIRSGGGSPTVHIGPTAFLGLGVVDNNG------NGARVQRVVGSAPAASLGISTGDVI  304
              I +G  + T HIG  A LG+ VV ++        G  VQ+V+  +  AS G++ GD I
Sbjct  300  DDILAGRKTTTNHIGAKAALGVAVVPSSSLRGASDTGVVVQQVLNGSAVASTGMTAGDTI  359

Query  305  TAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAE  351
            TA+DG  + S  +++  +   +PG  I VTW   SG + T +VTL +
Sbjct  360  TALDGKAVTSTDSLSSLMGTRYPGSTIKVTWSDTSGASHTASVTLQK  406


>gi|326334041|ref|ZP_08200270.1| putative serine protease [Nocardioidaceae bacterium Broad-1]
 gi|325948190|gb|EGD40301.1| putative serine protease [Nocardioidaceae bacterium Broad-1]
Length=374

 Score =  164 bits (414),  Expect = 3e-38, Method: Compositional matrix adjust.
 Identities = 123/297 (42%), Positives = 159/297 (54%), Gaps = 13/297 (4%)

Query  63   VVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYD  122
            VV ++T + Y  A GAGTG+ I  +G+V+TN+HV+ GAT I      +G TY   V+GYD
Sbjct  87   VVLVSTTVDYGTARGAGTGLTITADGIVVTNHHVVEGATSITVTDPSAGTTYDATVLGYD  146

Query  123  RTQDVAVLQLRGAGGLPSAAIGGGVAV-GEPVVAMGNSGGQGGTPRAVPGRVV--ALGQT  179
               DVAVLQL  A GL + A     A  GE V ++GN+ GQ G+  A  G V   +   T
Sbjct  147  DVHDVAVLQLEDASGLSTVATDRDAATRGEQVTSVGNAEGQ-GSLSAADGTVTDPSTAIT  205

Query  180  VQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASDNFQLSQGGQGF  239
            V   D   G    L  LI+ DA +  GDSGG +++  G+V+GMN AA+     S    G+
Sbjct  206  VNNED---GTTADLTDLIETDADVVSGDSGGALLDEDGEVIGMNVAATSG---SADISGY  259

Query  240  AIPIGQAMAIAGQIRSGGGSPTVHI-GPTAFLGLGVVDNNGNGARVQRVVGSAPAASLGI  298
            AIPI   + IA QI +G  S  V I GP A LG+ V  +      V  VV    A + GI
Sbjct  260  AIPIDTVLDIAAQILAGEESGDVEIGGPAAALGVQV--DTTRSTLVVGVVEDGAAEAGGI  317

Query  299  STGDVITAVDGAPINSATAMADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGPPA  355
            + G  IT+VDG  + S   +   L  H PGD ISV W   +G   T  VTL EGP A
Sbjct  318  AEGSTITSVDGTAVASIDDITSVLGNHEPGDRISVGWTDAAGEAHTATVTLGEGPVA  374


>gi|289705249|ref|ZP_06501648.1| trypsin [Micrococcus luteus SK58]
 gi|289557999|gb|EFD51291.1| trypsin [Micrococcus luteus SK58]
Length=393

 Score =  159 bits (403),  Expect = 5e-37, Method: Compositional matrix adjust.
 Identities = 113/302 (38%), Positives = 165/302 (55%), Gaps = 7/302 (2%)

Query  50   LDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVG  109
            LDP   VA   P ++ + T LG     G GTG+V+ P+G+ +TN HV+  +++++     
Sbjct  91   LDPGQPVAD-APGILLVETALGART--GTGTGMVLSPDGLTVTNYHVVEDSSEVHVVVAD  147

Query  110  SGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIG-GGVAVGEPVVAMGNSGGQGGTPRA  168
            +G  +   V+G D   D+AVL + G   LP A++    V  GE V A+GN GGQG    A
Sbjct  148  TGARHTATVLGRDAEHDIAVLDVEGVSDLPVASVSLDPVRRGETVAAVGNGGGQGYL-TA  206

Query  169  VPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASD  228
            V G V+   +++ A+   T     L+GLIQ DA + PG SGGPVV+  GQVVG+  AASD
Sbjct  207  VRGTVLGTDRSIMAAAEGTDQYARLSGLIQTDADVVPGYSGGPVVDDAGQVVGVTVAASD  266

Query  229  NFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVV  288
                 +   GFAIP+  A  +  Q+ SG  + TV IG    LG+ V  +   G  V +V 
Sbjct  267  GTTADE-VDGFAIPLEVAFDVVDQVLSGEETDTVSIGADGALGIMVGADPDVGVVVMQVD  325

Query  289  GSAPAASLGISTGDVITAVDGAPI-NSATAMADALNGHHPGDVISVTWQTKSGGTRTGNV  347
              + A  +G+  GDVI  ++G P+ + A+ M+  +N H+ GD I+V W+T  G  R    
Sbjct  326  AGSAAEQIGLVEGDVILEIEGRPVGDDASRMSRLVNDHNVGDRITVQWRTADGEVREAEA  385

Query  348  TL  349
             L
Sbjct  386  VL  387


>gi|239918048|ref|YP_002957606.1| trypsin-like serine protease with C-terminal PDZ domain [Micrococcus 
luteus NCTC 2665]
 gi|281415773|ref|ZP_06247515.1| trypsin-like serine protease with C-terminal PDZ domain [Micrococcus 
luteus NCTC 2665]
 gi|239839255|gb|ACS31052.1| trypsin-like serine protease with C-terminal PDZ domain [Micrococcus 
luteus NCTC 2665]
Length=393

 Score =  154 bits (388),  Expect = 3e-35, Method: Compositional matrix adjust.
 Identities = 111/302 (37%), Positives = 163/302 (54%), Gaps = 7/302 (2%)

Query  50   LDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFSVG  109
            LDP   VA   P ++ + T LG     G GTG+V+ P+G+ +TN HV+  +++++     
Sbjct  91   LDPGQPVAD-APGILLVETALGART--GTGTGMVLSPDGLAVTNYHVVEDSSEVHVVVAD  147

Query  110  SGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIG-GGVAVGEPVVAMGNSGGQGGTPRA  168
            +G  +   V+G D   D+AVL + G   LP A++    V  GE V A+GN GGQG    A
Sbjct  148  TGARHTATVLGRDAEHDIAVLDVEGVSDLPVASVSLDPVRRGETVAAVGNGGGQGHL-TA  206

Query  169  VPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTAASD  228
            V G V+   +++ A+   T     L+GLIQ DA + PG SGGPVV+  GQVVG+  AASD
Sbjct  207  VRGTVLGTDRSIMAAAEGTDQYARLSGLIQTDADVVPGYSGGPVVDDAGQVVGVTVAASD  266

Query  229  NFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVDNNGNGARVQRVV  288
                 +   GFAIP+  A  +  Q+ SG  + TV IG    LG+ V  +   G  V +V 
Sbjct  267  GTTADE-VDGFAIPLEVAFDVVDQVLSGEETDTVSIGADGALGIMVGADPDVGVVVMQVD  325

Query  289  GSAPAASLGISTGDVITAVDGAPI-NSATAMADALNGHHPGDVISVTWQTKSGGTRTGNV  347
              + A  +G+  GDVI  ++G  + + A+ M+  +N H+ GD I+V W+T  G       
Sbjct  326  AGSAAEQIGLVEGDVILEIEGRAVGDDASRMSRLVNDHNVGDRITVQWRTADGEVHEAEA  385

Query  348  TL  349
             L
Sbjct  386  VL  387


>gi|336178408|ref|YP_004583783.1| peptidase S1 and S6 chymotrypsin/Hap [Frankia symbiont of Datisca 
glomerata]
 gi|334859388|gb|AEH09862.1| peptidase S1 and S6 chymotrypsin/Hap [Frankia symbiont of Datisca 
glomerata]
Length=426

 Score =  153 bits (387),  Expect = 3e-35, Method: Compositional matrix adjust.
 Identities = 107/251 (43%), Positives = 151/251 (61%), Gaps = 17/251 (6%)

Query  48   LPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATDINAFS  107
            +P   SA   +V P VV + +++   NA  AGTG+V++ +G VLTNNHVIA A  I    
Sbjct  103  VPAQLSAATDRVLPGVVRVFSRITSQNASAAGTGMVLNASGEVLTNNHVIANADAITVTV  162

Query  108  VGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEPVVAMGNSGGQGGT  165
              SG++Y   VVG D   DVAVL+L+GA GL +  IG    V V + V A+GN+  +GG 
Sbjct  163  TSSGRSYQASVVGTDMADDVAVLRLQGASGLAAVPIGDSSRVGVSDSVAAIGNA--EGGA  220

Query  166  PRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQVVGMNTA  225
            P  V GR+ AL Q++ A+DS  G  E L+GLI+ D AI+PG SGGP+V+  G+V+GM+TA
Sbjct  221  PEVVSGRITALNQSITATDSDGGNPEDLSGLIKTDVAIRPGFSGGPLVSSAGEVIGMDTA  280

Query  226  ASD-NFQLSQGGQ-GFAIPIGQAMAIAGQIRSGGGSPTVHI-------GPTAFLGLGVVD  276
            A+  N  L  G + G+AIPI  A+++A  + +G  +    I       GP+A  G GV  
Sbjct  281  ATAFNEYLPAGLRAGYAIPISHAISVASSLSAGKSAGKTAIVSAARVEGPSARSGSGVTV  340

Query  277  NNGNGARVQRV  287
            +    AR+ R+
Sbjct  341  D----ARLARL  347


>gi|256371520|ref|YP_003109344.1| peptidase S1 and S6 chymotrypsin/Hap [Acidimicrobium ferrooxidans 
DSM 10331]
 gi|256008104|gb|ACU53671.1| peptidase S1 and S6 chymotrypsin/Hap [Acidimicrobium ferrooxidans 
DSM 10331]
Length=392

 Score =  153 bits (387),  Expect = 4e-35, Method: Compositional matrix adjust.
 Identities = 129/336 (39%), Positives = 176/336 (53%), Gaps = 43/336 (12%)

Query  54   AMVAQVGPQVVNINTK---LGYNNAV--------------GAGTGIVIDPNGVVLTNNHV  96
            A+V+ V P+VV+I+     +G  N                 AGTG+++  +G+VLTNNHV
Sbjct  62   AIVSSVLPEVVSIDATGDLIGVTNGGPFGLGGGQTGAEFKSAGTGMIVSTSGLVLTNNHV  121

Query  97   IAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQL-RGAGGLPSAAIGGGVAV--GEPV  153
            IAGAT +     G+       +VG   + D+A+L++      L +   G   A+  G+ V
Sbjct  122  IAGATSVAVTLDGTHTALPATIVGTIPSHDLALLRIDHPPAHLHTVTFGDSAALVPGDAV  181

Query  154  VAMGNSGG-QGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPV  212
            +A+GN+ G Q G+P    G V ALG+ V AS   TG  ETL+ +IQ DAAI PG+SGGP+
Sbjct  182  IAIGNALGLQAGSPTVTSGIVSALGRVVTASIPTTGQTETLDDMIQTDAAINPGNSGGPL  241

Query  213  VNGLGQVVGMNTAASDNFQLSQGGQ----GFAIPIGQAMAIAGQIRSGGGSPTVHIGPTA  268
            V+  G VVGMNTAA+     S G Q    GFAIP  + +A    +  GG S      P A
Sbjct  242  VDSAGDVVGMNTAAAGT--TSDGTQAENIGFAIPSSELIAELPVLEHGGTSG----APGA  295

Query  269  FLGLGVVDNN-----------GNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATA  317
            FLG+ V D++             GA V  V+    AA  G+S GDVI A DG  + SA A
Sbjct  296  FLGVEVEDDSSALAAQFGLPVSQGAVVVSVLPGTAAAQAGLSAGDVIVAFDGHKVTSAAA  355

Query  318  MADALNGHHPGDVISVTWQTKSGGTRTGNVTLAEGP  353
            +       HPGD +S+++ T S   RT  VTL   P
Sbjct  356  LGAIEETLHPGDQVSLSYWTSS-SERTVTVTLGTRP  390


>gi|269929247|ref|YP_003321568.1| HtrA2 peptidase [Sphaerobacter thermophilus DSM 20745]
 gi|269788604|gb|ACZ40746.1| HtrA2 peptidase [Sphaerobacter thermophilus DSM 20745]
Length=401

 Score =  147 bits (372),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 120/320 (38%), Positives = 171/320 (54%), Gaps = 21/320 (6%)

Query  33   APP--ALSQDRFADFPALPLDPSAMVAQVGPQVVNINTKLGYNNAV-----GAGTGIVID  85
            APP  A++Q    DF    +  S  V     QV +  T+    N       G G+G++ D
Sbjct  67   APPNVAVAQPLSGDFIGAVIAVSQRVKPAVVQVTSEQTRFDLFNQPFTVPGGVGSGVIYD  126

Query  86   PNGVVLTNNHVIAGATDINAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIG-  144
             +G +LTN HVIAGA  +   S+  G+++  DVVG D   D+AVL++ G   LP+A +G 
Sbjct  127  QDGYILTNYHVIAGAESLR-VSLPDGRSFPADVVGTDPQTDLAVLKIDGED-LPTAPLGD  184

Query  145  -GGVAVGEPVVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAI  203
               + VGE VVA+GN+    G P    G V AL +TVQ       A   L  +IQ DAAI
Sbjct  185  SNKLQVGEWVVAIGNALALPGGPTVTVGVVSALNRTVQEPGEGGRAGPFLFNVIQTDAAI  244

Query  204  QPGDSGGPVVNGLGQVVGMNTAASDNFQ--LSQGGQGFAIPIGQAMAIAGQIRSGGGSPT  261
             PG+SGGP+VN  G+V+G+NT  +   Q  L   G GFA+ I     +A +I + G    
Sbjct  245  NPGNSGGPLVNLAGEVIGINTLVAGTTQSGLQAEGIGFALAISTVKPLADEIVATGQVTH  304

Query  262  VHIG-------PTAFLGLGVVDNNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINS  314
             +IG       P     LG ++   +GA V  VVG +PA   G+   DVIT +DG P+ +
Sbjct  305  PYIGIRYTQLTPAIAAQLG-IEGATSGAVVIEVVGGSPAEEAGLQPRDVITEIDGQPLTT  363

Query  315  ATAMADALNGHHPGDVISVT  334
             +++A+ +N H PGD I++T
Sbjct  364  ESSLAEIINTHRPGDTITLT  383


>gi|240169346|ref|ZP_04748005.1| heat shock protein HtrA, putative [Mycobacterium kansasii ATCC 
12478]
Length=364

 Score =  145 bits (367),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 125/326 (39%), Positives = 180/326 (56%), Gaps = 30/326 (9%)

Query  43   ADFPALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATD  102
            A+ PA  ++  A  A+V P VV + T LG   A   G+G+++  +G++LTNNHV+A A  
Sbjct  49   ANMPAGSVEQVA--AKVVPSVVMLETDLGR--ASEEGSGVILSSDGLILTNNHVVAAAAK  104

Query  103  I--------NAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGG--VAVGEP  152
                        +   G+T    VVG D T D+AV++++G  GL   ++G    + VG+P
Sbjct  105  PPAGAPPPKTTVTFSDGRTAPFTVVGADPTSDIAVIKVQGVSGLTPISLGSSSDLRVGQP  164

Query  153  VVAMGNSGGQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPV  212
            V+A+G+  G  GT     G V AL + V  +    G + T+   IQ DAAI PG+SGG +
Sbjct  165  VLAIGSPLGLAGT--VTTGIVSALNRPVSTTGE-AGNQNTVLDAIQTDAAINPGNSGGAL  221

Query  213  VNGLGQVVGMNTAA------SDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGP  266
            VN  GQ+VG+N+A       S + Q    G GFAIP+ QA  IA ++ S G +   H   
Sbjct  222  VNMNGQLVGINSAIATLGADSGDAQSGSIGLGFAIPVDQAKRIADELISTGKA--TH---  276

Query  267  TAFLGLGVVDNNG-NGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGH  325
             A LG+ V  + G  GA+V  VV    AA+ G+  G ++T VD  PINSA A+  A+   
Sbjct  277  -ASLGVQVTTDKGIPGAKVVEVVQGGAAATAGVPKGVIVTKVDERPINSADALVAAVRSK  335

Query  326  HPGDVISVTWQTKSGGTRTGNVTLAE  351
             PGD + +T+Q  SGG+RT  VTL +
Sbjct  336  APGDKVVLTFQDPSGGSRTVQVTLGK  361



Lambda     K      H
   0.314    0.133    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 663860846620




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40