BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0134

Length=300
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607276|ref|NP_214648.1|  epoxide hydrolase EphF [Mycobacteri...   602    2e-170
gi|148821326|ref|YP_001286080.1|  epoxide hydrolase ephF [Mycobac...   600    6e-170
gi|340625169|ref|YP_004743621.1|  putative epoxide hydrolase EPHF...   600    1e-169
gi|240168133|ref|ZP_04746792.1|  epoxide hydrolase EphF [Mycobact...   516    2e-144
gi|342859437|ref|ZP_08716091.1|  alpha/beta hydrolase [Mycobacter...   494    1e-137
gi|41409648|ref|NP_962484.1|  EphF [Mycobacterium avium subsp. pa...   481    4e-134
gi|254822374|ref|ZP_05227375.1|  hydrolase, alpha/beta fold famil...   481    8e-134
gi|296167322|ref|ZP_06849724.1|  epoxide hydrolase [Mycobacterium...   480    1e-133
gi|183980373|ref|YP_001848664.1|  epoxide hydrolase EphF [Mycobac...   478    4e-133
gi|118619834|ref|YP_908166.1|  epoxide hydrolase EphF [Mycobacter...   478    4e-133
gi|111025454|ref|YP_707874.1|  epoxide hydrolase/ haloalkane deha...   424    1e-116
gi|289572713|ref|ZP_06452940.1|  LOW QUALITY PROTEIN: epoxide hyd...   348    8e-94 
gi|298527524|ref|ZP_07014933.1|  epoxide hydrolase [Mycobacterium...   343    2e-92 
gi|289441506|ref|ZP_06431250.1|  epoxide hydrolase ephF [Mycobact...   303    1e-80 
gi|289747901|ref|ZP_06507279.1|  epoxide hydrolase ephF [Mycobact...   257    2e-66 
gi|284045647|ref|YP_003395987.1|  alpha/beta hydrolase fold prote...   209    3e-52 
gi|169631596|ref|YP_001705245.1|  epoxide hydrolase EphF [Mycobac...   189    4e-46 
gi|311896903|dbj|BAJ29311.1|  putative hydrolase [Kitasatospora s...   180    2e-43 
gi|256395267|ref|YP_003116831.1|  alpha/beta hydrolase fold prote...   178    7e-43 
gi|317509219|ref|ZP_07966840.1|  alpha/beta hydrolase [Segnilipar...   165    7e-39 
gi|304570623|ref|YP_830541.2|  alpha/beta hydrolase fold [Arthrob...   162    8e-38 
gi|315442997|ref|YP_004075876.1|  hydrolase or acyltransferase of...   160    2e-37 
gi|256833681|ref|YP_003162408.1|  alpha/beta hydrolase fold prote...   159    3e-37 
gi|120405714|ref|YP_955543.1|  alpha/beta hydrolase fold protein ...   157    2e-36 
gi|145222550|ref|YP_001133228.1|  alpha/beta hydrolase fold prote...   155    6e-36 
gi|116609717|gb|ABK02441.1|  alpha/beta hydrolase fold protein [A...   146    4e-33 
gi|311743374|ref|ZP_07717181.1|  possible epoxide hydrolase EphF ...   145    7e-33 
gi|163853241|ref|YP_001641284.1|  alpha/beta hydrolase fold prote...   145    7e-33 
gi|240140648|ref|YP_002965128.1|  alpha/beta hydrolase, epoxide h...   145    1e-32 
gi|254563162|ref|YP_003070257.1|  alpha/beta hydrolase [Methyloba...   144    1e-32 
gi|218532056|ref|YP_002422872.1|  alpha/beta hydrolase fold prote...   143    3e-32 
gi|298246057|ref|ZP_06969863.1|  alpha/beta hydrolase fold protei...   136    3e-30 
gi|288556239|ref|YP_003428174.1|  putative hydrolase [Bacillus ps...   136    4e-30 
gi|294506178|ref|YP_003570236.1|  alpha/beta hydrolase [Salinibac...   134    1e-29 
gi|83815536|ref|YP_444434.1|  alpha/beta fold family hydrolase [S...   134    2e-29 
gi|188583494|ref|YP_001926939.1|  alpha/beta hydrolase fold prote...   132    8e-29 
gi|322371791|ref|ZP_08046334.1|  alpha/beta hydrolase fold protei...   131    1e-28 
gi|170747053|ref|YP_001753313.1|  alpha/beta hydrolase fold prote...   130    2e-28 
gi|312194226|ref|YP_004014287.1|  alpha/beta hydrolase fold prote...   130    2e-28 
gi|288918359|ref|ZP_06412712.1|  alpha/beta hydrolase fold protei...   130    3e-28 
gi|325282394|ref|YP_004254935.1|  Soluble epoxide hydrolase [Dein...   128    1e-27 
gi|296268202|ref|YP_003650834.1|  alpha/beta hydrolase fold prote...   126    4e-27 
gi|226356217|ref|YP_002785957.1|  hydrolase [Deinococcus deserti ...   126    4e-27 
gi|56693357|ref|NP_001008642.1|  epoxide hydrolase 2 [Danio rerio...   125    1e-26 
gi|115374710|ref|ZP_01461987.1|  alpha/beta hydrolase [Stigmatell...   124    1e-26 
gi|115435726|ref|NP_001042621.1|  Os01g0255000 [Oryza sativa Japo...   124    1e-26 
gi|167644459|ref|YP_001682122.1|  alpha/beta hydrolase fold prote...   124    2e-26 
gi|56962533|ref|YP_174259.1|  hypothetical protein ABC0759 [Bacil...   124    3e-26 
gi|197105739|ref|YP_002131116.1|  epoxide hydrolase [Phenylobacte...   122    9e-26 
gi|225431774|ref|XP_002270883.1|  PREDICTED: hypothetical protein...   120    2e-25 


>gi|15607276|ref|NP_214648.1| epoxide hydrolase EphF [Mycobacterium tuberculosis H37Rv]
 gi|15839515|ref|NP_334552.1| epoxide hydrolase [Mycobacterium tuberculosis CDC1551]
 gi|148659898|ref|YP_001281421.1| epoxide hydrolase EphF [Mycobacterium tuberculosis H37Ra]
 37 more sequence titles
 Length=300

 Score =  602 bits (1552),  Expect = 2e-170, Method: Compositional matrix adjust.
 Identities = 300/300 (100%), Positives = 300/300 (100%), Gaps = 0/300 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG
Sbjct  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
            NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR
Sbjct  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG
Sbjct  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW
Sbjct  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300
            LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD
Sbjct  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300


>gi|148821326|ref|YP_001286080.1| epoxide hydrolase ephF [Mycobacterium tuberculosis F11]
 gi|253797053|ref|YP_003030054.1| epoxide hydrolase ephF [Mycobacterium tuberculosis KZN 1435]
 gi|254549069|ref|ZP_05139516.1| epoxide hydrolase ephF [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 11 more sequence titles
 Length=300

 Score =  600 bits (1548),  Expect = 6e-170, Method: Compositional matrix adjust.
 Identities = 299/300 (99%), Positives = 299/300 (99%), Gaps = 0/300 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG
Sbjct  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
            NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR
Sbjct  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG
Sbjct  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW
Sbjct  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300
            LHGTGDPVITPDLLDGYAERASDFEVELVD VGHWIVEQRPELVLDRVRAFLAAGTEQRD
Sbjct  241  LHGTGDPVITPDLLDGYAERASDFEVELVDSVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300


>gi|340625169|ref|YP_004743621.1| putative epoxide hydrolase EPHF [Mycobacterium canettii CIPT 
140010059]
 gi|340003359|emb|CCC42478.1| putative epoxide hydrolase EPHF (epoxide hydratase) (arene-oxide 
hydratase) [Mycobacterium canettii CIPT 140010059]
Length=300

 Score =  600 bits (1546),  Expect = 1e-169, Method: Compositional matrix adjust.
 Identities = 299/300 (99%), Positives = 299/300 (99%), Gaps = 0/300 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWR LIGPLAADG
Sbjct  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRALIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
            NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR
Sbjct  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG
Sbjct  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW
Sbjct  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300
            LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD
Sbjct  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300


>gi|240168133|ref|ZP_04746792.1| epoxide hydrolase EphF [Mycobacterium kansasii ATCC 12478]
Length=291

 Score =  516 bits (1329),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 248/291 (86%), Positives = 274/291 (95%), Gaps = 0/291 (0%)

Query  4    LPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRV  63
            +PAL+GVEHR VDV +GV IHVADAGPADGPAVMLVHGFP+NWWEW  LIGPLAADG RV
Sbjct  1    MPALDGVEHRFVDVGDGVTIHVADAGPADGPAVMLVHGFPENWWEWHKLIGPLAADGYRV  60

Query  64   LCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPE  123
            LCPDLRGAGWSSAPRSRY K+EMADDLAAVLD LGVA+VKLVAHDWGGPVAFIMMLR+P 
Sbjct  61   LCPDLRGAGWSSAPRSRYLKSEMADDLAAVLDRLGVAEVKLVAHDWGGPVAFIMMLRYPA  120

Query  124  KVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVG  183
            KVTGFFG+NT APWV+RDLGMLR+MWRFWYQ+PMSLPVIGPR+I+DPK R+FR+LT WVG
Sbjct  121  KVTGFFGLNTSAPWVRRDLGMLRHMWRFWYQVPMSLPVIGPRLIADPKARFFRMLTSWVG  180

Query  184  GGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHG  243
            GG+RVPD+DVR+Y+DCMR+PGHAEAGSRWYR+FQT EMLRWLRGEYND RV+VPVRWLHG
Sbjct  181  GGYRVPDEDVRMYVDCMRQPGHAEAGSRWYRSFQTTEMLRWLRGEYNDKRVEVPVRWLHG  240

Query  244  TGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAA  294
            TGDPVITP+LL GY +RASDFEVELVDGVGHWIVEQRP+LVLDR+RAFL A
Sbjct  241  TGDPVITPNLLRGYEDRASDFEVELVDGVGHWIVEQRPDLVLDRLRAFLTA  291


>gi|342859437|ref|ZP_08716091.1| alpha/beta hydrolase [Mycobacterium colombiense CECT 3035]
 gi|342133678|gb|EGT86881.1| alpha/beta hydrolase [Mycobacterium colombiense CECT 3035]
Length=292

 Score =  494 bits (1271),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 235/290 (82%), Positives = 263/290 (91%), Gaps = 0/290 (0%)

Query  4    LPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRV  63
            +PAL+GVEHR+VD+  GV IHVADAGPA GPAVMLVHGFPQNWWEWR+LIGPLAADG RV
Sbjct  1    MPALDGVEHRYVDLGSGVTIHVADAGPASGPAVMLVHGFPQNWWEWRELIGPLAADGYRV  60

Query  64   LCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPE  123
            LCPDLRG+GWSSAPR+ YTK EMADDLA VL+ LGVA VKLVAHDWGGPVAFIMMLRHPE
Sbjct  61   LCPDLRGSGWSSAPRTSYTKDEMADDLAGVLERLGVATVKLVAHDWGGPVAFIMMLRHPE  120

Query  124  KVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVG  183
            +VTGFFGVNTVAPWVK  L  LRN+WRFWYQIP+SLPVIGPRVISDP  R+ R+L  WVG
Sbjct  121  RVTGFFGVNTVAPWVKPSLSTLRNIWRFWYQIPISLPVIGPRVISDPNSRFVRMLGSWVG  180

Query  184  GGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHG  243
            GG+ +P+DD R+YL+CM++PGHAEAGSRWYR+FQT+EM +W+RG+YNDARVDVPVRWL G
Sbjct  181  GGYTLPEDDTRMYLECMQQPGHAEAGSRWYRSFQTKEMRKWMRGQYNDARVDVPVRWLTG  240

Query  244  TGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            T DPVITPDL DGYA+R  DFEVELVDGVGHWIV+QRP+LVLDRVRAFLA
Sbjct  241  TEDPVITPDLTDGYADRIDDFEVELVDGVGHWIVDQRPDLVLDRVRAFLA  290


>gi|41409648|ref|NP_962484.1| EphF [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118464795|ref|YP_884280.1| alpha/beta hydrolase [Mycobacterium avium 104]
 gi|254777505|ref|ZP_05219021.1| hydrolase, alpha/beta fold family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
 gi|41398480|gb|AAS06100.1| EphF [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118166082|gb|ABK66979.1| hydrolase, alpha/beta fold family protein [Mycobacterium avium 
104]
 gi|336459913|gb|EGO38825.1| putative hydrolase or acyltransferase of alpha/beta superfamily 
[Mycobacterium avium subsp. paratuberculosis S397]
Length=296

 Score =  481 bits (1239),  Expect = 4e-134, Method: Compositional matrix adjust.
 Identities = 234/296 (80%), Positives = 259/296 (88%), Gaps = 0/296 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            M+ +P L+GVEHR+VD+ + V IHVADAGPA GPAVMLVHGFPQNWWEWR LIGPLAADG
Sbjct  1    MVTMPELDGVEHRYVDLGDDVTIHVADAGPASGPAVMLVHGFPQNWWEWRALIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
             RVLCPDLRGAGWSSAPRS Y K EMADDLA VLD LGV  V LVAHDWGGPVAFIMMLR
Sbjct  61   YRVLCPDLRGAGWSSAPRSSYRKDEMADDLAGVLDRLGVRSVDLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            HPEKVTGFFGVNT AP+VKR L  +RN+WRFWYQIP+SLPVIGPRVIS P  R+ RLL  
Sbjct  121  HPEKVTGFFGVNTSAPFVKRSLSTIRNVWRFWYQIPISLPVIGPRVISTPDSRFVRLLGS  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGG+ +P++DVRLYL+CMR+PGHAEAGSRWYR+FQTREML W+RGEY+ ARV VPVRW
Sbjct  181  WVGGGYTLPEEDVRLYLECMRQPGHAEAGSRWYRSFQTREMLSWMRGEYDGARVHVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGT  296
            L GT DPV+TPDLLDGYAER  DF++ELVDGVGHWIV+QRP+LVLDRVRAFL   T
Sbjct  241  LSGTEDPVLTPDLLDGYAERIDDFQLELVDGVGHWIVDQRPDLVLDRVRAFLRRET  296


>gi|254822374|ref|ZP_05227375.1| hydrolase, alpha/beta fold family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=295

 Score =  481 bits (1237),  Expect = 8e-134, Method: Compositional matrix adjust.
 Identities = 232/293 (80%), Positives = 259/293 (89%), Gaps = 0/293 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            M+ +PAL+GVEHR+V++  GV IHVADAGPA GPAVMLVHGFPQNWWEWR+LIGPLAADG
Sbjct  1    MVTMPALDGVEHRYVELGNGVTIHVADAGPASGPAVMLVHGFPQNWWEWRELIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
             RVLCPDLRG+GWSSAPR+ Y K EMADDLA VLD LGVA VKLVAHDWGGP AFIMMLR
Sbjct  61   YRVLCPDLRGSGWSSAPRTSYRKDEMADDLARVLDRLGVASVKLVAHDWGGPAAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            HP+KVTGFFGVNT AP+VKR   MLRN+WRFWYQIP+SLPVIGPRVIS    R+ RLL  
Sbjct  121  HPDKVTGFFGVNTSAPFVKRSPSMLRNVWRFWYQIPISLPVIGPRVISASNPRFLRLLGS  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGG+ +P++DVRLYL+CMR+PGHAEAGSRWYR+FQTREML W+RGEY+ ARVDVPVRW
Sbjct  181  WVGGGYTLPEEDVRLYLECMRQPGHAEAGSRWYRSFQTREMLSWMRGEYDGARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            L GT DPVIT DL +GYA+   DFEVELVDGVGHWIV+QRP+LVLDRVRAFLA
Sbjct  241  LTGTEDPVITADLTEGYADHIKDFEVELVDGVGHWIVDQRPDLVLDRVRAFLA  293


>gi|296167322|ref|ZP_06849724.1| epoxide hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897266|gb|EFG76870.1| epoxide hydrolase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=296

 Score =  480 bits (1236),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 235/296 (80%), Positives = 260/296 (88%), Gaps = 0/296 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            M+ +P L+GVEHR+VDV  GV IHVADAGP DGPAVMLVHGFPQNWWEW  LIGPLAADG
Sbjct  1    MVTMPELDGVEHRYVDVGSGVTIHVADAGPGDGPAVMLVHGFPQNWWEWHHLIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
             RVLCPDLRGAGWSSAPR+ YTK EMA+DLAAVLD L V  VKLVAHDWGGPVAFIMMLR
Sbjct  61   YRVLCPDLRGAGWSSAPRTSYTKAEMAEDLAAVLDLLDVRTVKLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            HPEKVTGFFGVNTVAPWVKRDL  +RN+WRFWYQIP+SLPVIGPR+ISD + R  R +  
Sbjct  121  HPEKVTGFFGVNTVAPWVKRDLRAVRNIWRFWYQIPISLPVIGPRMISDLESRIGRWMGS  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGG+ +P++D RLY++CMR+PGHAEAGSRWYR+FQT EMLRW RGEY+DARVDVPVRW
Sbjct  181  WVGGGYALPEEDTRLYIECMRQPGHAEAGSRWYRSFQTGEMLRWARGEYDDARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGT  296
            L GT DPVITP+L DGYA+  SDF+VELVDGVGHWIV+QRPELVLDRVRAFL   T
Sbjct  241  LTGTLDPVITPELTDGYADHISDFKVELVDGVGHWIVDQRPELVLDRVRAFLRGET  296


>gi|183980373|ref|YP_001848664.1| epoxide hydrolase EphF [Mycobacterium marinum M]
 gi|183173699|gb|ACC38809.1| epoxide hydrolase EphF [Mycobacterium marinum M]
Length=296

 Score =  478 bits (1231),  Expect = 4e-133, Method: Compositional matrix adjust.
 Identities = 232/296 (79%), Positives = 259/296 (88%), Gaps = 0/296 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            M  LPAL+GVEHR VD+  G+ IHVADAGPADGPAVMLVHGFP+NWWEW +LIGPLAADG
Sbjct  1    MSTLPALDGVEHRFVDLDGGITIHVADAGPADGPAVMLVHGFPENWWEWHELIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
             RVLCPDLRGAGWSSAPRSRYTK EMADDLA VLD LG+A V+LVAHDWGGPVAFIMMLR
Sbjct  61   YRVLCPDLRGAGWSSAPRSRYTKKEMADDLAGVLDRLGIASVRLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            +P KVTGFFG+NT APW  RDLGM+R++WRFWYQIP+ LPVIGPRVI+DPK RYFR+LT 
Sbjct  121  YPAKVTGFFGMNTAAPWFPRDLGMVRDIWRFWYQIPIMLPVIGPRVIADPKARYFRVLTS  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGGF + D+DVR+Y++ MR+PGHA AGSRWYRTFQ+ E L W+RGEY DARVDVPVRW
Sbjct  181  WVGGGFTIADEDVRMYVERMRQPGHAVAGSRWYRTFQSSEALPWMRGEYADARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGT  296
            LHGT DPV+TP LL GY +  SDFEVE VDGVGHWIVEQRP+LVLDR+RAFL   T
Sbjct  241  LHGTEDPVLTPQLLRGYEDHISDFEVEFVDGVGHWIVEQRPDLVLDRLRAFLRIET  296


>gi|118619834|ref|YP_908166.1| epoxide hydrolase EphF [Mycobacterium ulcerans Agy99]
 gi|118571944|gb|ABL06695.1| epoxide hydrolase EphF [Mycobacterium ulcerans Agy99]
Length=296

 Score =  478 bits (1230),  Expect = 4e-133, Method: Compositional matrix adjust.
 Identities = 232/296 (79%), Positives = 259/296 (88%), Gaps = 0/296 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            M  LPAL+GVEHR VD+  G+ IHVADAGPADGPAVMLVHGFP+NWWEW +LIGPLAADG
Sbjct  1    MSTLPALDGVEHRFVDLDGGITIHVADAGPADGPAVMLVHGFPENWWEWHELIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
             RVLCPDLRGAGWSSAPRSRYTK EMADDLA VLD LG+A V+LVAHDWGGPVAFIMMLR
Sbjct  61   YRVLCPDLRGAGWSSAPRSRYTKKEMADDLAGVLDRLGIASVRLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
            +P KVTGFFG+NT APW  RDLGM+R++WRFWYQIP+ LPVIGPRVI+DPK RYFR+LT 
Sbjct  121  YPAKVTGFFGMNTAAPWFPRDLGMVRDIWRFWYQIPILLPVIGPRVIADPKARYFRVLTS  180

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
            WVGGGF + D+DVR+Y++ MR+PGHA AGSRWYRTFQ+ E L W+RGEY DARVDVPVRW
Sbjct  181  WVGGGFTIADEDVRMYVERMRQPGHAVAGSRWYRTFQSSEALPWMRGEYADARVDVPVRW  240

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGT  296
            LHGT DPV+TP LL GY +  SDFEVE VDGVGHWIVEQRP+LVLDR+RAFL   T
Sbjct  241  LHGTDDPVLTPQLLRGYEDHISDFEVEFVDGVGHWIVEQRPDLVLDRLRAFLRIET  296


>gi|111025454|ref|YP_707874.1| epoxide hydrolase/ haloalkane dehalogenase [Rhodococcus jostii 
RHA1]
 gi|110824433|gb|ABG99716.1| probable epoxide hydrolase/ haloalkane dehalogenase [Rhodococcus 
jostii RHA1]
Length=295

 Score =  424 bits (1089),  Expect = 1e-116, Method: Compositional matrix adjust.
 Identities = 207/290 (72%), Positives = 240/290 (83%), Gaps = 2/290 (0%)

Query  3    ALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNR  62
            +LP L GVEHR VDV  GV IHVADAGPADG  VMLVHGFPQNWW W +LIGPLAADG R
Sbjct  5    SLPVLAGVEHRFVDVGGGVTIHVADAGPADGSPVMLVHGFPQNWWAWHELIGPLAADGYR  64

Query  63   VLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHP  122
            VLCPDLRGAGWSSAP  RY KT+MADDLA VLD LGVA V++VAHDWGGP+A  +MLRHP
Sbjct  65   VLCPDLRGAGWSSAPDGRYYKTDMADDLAVVLDRLGVAPVRVVAHDWGGPIAAHLMLRHP  124

Query  123  EKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWV  182
            +KV+GFFG+NTV PW+  DL  +R++WRFWYQIP+SLPVIGPR++SDPKGR+ R+   WV
Sbjct  125  KKVSGFFGLNTVGPWLTFDLTAVRHLWRFWYQIPISLPVIGPRLLSDPKGRFIRMTGRWV  184

Query  183  GGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLH  242
            G GF + DDD RLY+ CMR PGH+ AGSRWYRTF TRE++R   GE+ +  VDVP+R+LH
Sbjct  185  GAGFYLDDDDFRLYVRCMRLPGHSVAGSRWYRTFLTRELIR--AGEFANTSVDVPMRFLH  242

Query  243  GTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            G GDPVITP LL GYAE A  F +E VDGVGHW+V+QRPELVL+R+RAFL
Sbjct  243  GVGDPVITPTLLRGYAEHAGGFRLETVDGVGHWVVDQRPELVLERLRAFL  292


>gi|289572713|ref|ZP_06452940.1| LOW QUALITY PROTEIN: epoxide hydrolase ephF [Mycobacterium tuberculosis 
K85]
 gi|289760234|ref|ZP_06519612.1| LOW QUALITY PROTEIN: predicted protein [Mycobacterium tuberculosis 
T85]
 gi|289537144|gb|EFD41722.1| LOW QUALITY PROTEIN: epoxide hydrolase ephF [Mycobacterium tuberculosis 
K85]
 gi|289715798|gb|EFD79810.1| LOW QUALITY PROTEIN: predicted protein [Mycobacterium tuberculosis 
T85]
Length=212

 Score =  348 bits (892),  Expect = 8e-94, Method: Compositional matrix adjust.
 Identities = 172/172 (100%), Positives = 172/172 (100%), Gaps = 0/172 (0%)

Query  129  FGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRV  188
            FGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRV
Sbjct  41   FGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRV  100

Query  189  PDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPV  248
            PDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPV
Sbjct  101  PDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPV  160

Query  249  ITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300
            ITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD
Sbjct  161  ITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  212


>gi|298527524|ref|ZP_07014933.1| epoxide hydrolase [Mycobacterium tuberculosis 94_M4241A]
 gi|298497318|gb|EFI32612.1| epoxide hydrolase [Mycobacterium tuberculosis 94_M4241A]
 gi|339293199|gb|AEJ45310.1| epoxide hydrolase EphF [Mycobacterium tuberculosis CCDC5079]
 gi|339296846|gb|AEJ48956.1| epoxide hydrolase EphF [Mycobacterium tuberculosis CCDC5180]
Length=170

 Score =  343 bits (880),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 169/170 (99%), Positives = 170/170 (100%), Gaps = 0/170 (0%)

Query  131  VNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPD  190
            +NTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPD
Sbjct  1    MNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPD  60

Query  191  DDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVIT  250
            DDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVIT
Sbjct  61   DDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVIT  120

Query  251  PDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  300
            PDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD
Sbjct  121  PDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQRD  170


>gi|289441506|ref|ZP_06431250.1| epoxide hydrolase ephF [Mycobacterium tuberculosis T46]
 gi|289568028|ref|ZP_06448255.1| epoxide hydrolase ephF [Mycobacterium tuberculosis T17]
 gi|289748609|ref|ZP_06507987.1| epoxide hydrolase ephF [Mycobacterium tuberculosis T92]
 gi|289756197|ref|ZP_06515575.1| epoxide hydrolase EphF [Mycobacterium tuberculosis EAS054]
 gi|289414425|gb|EFD11665.1| epoxide hydrolase ephF [Mycobacterium tuberculosis T46]
 gi|289541781|gb|EFD45430.1| epoxide hydrolase ephF [Mycobacterium tuberculosis T17]
 gi|289689196|gb|EFD56625.1| epoxide hydrolase ephF [Mycobacterium tuberculosis T92]
 gi|289696784|gb|EFD64213.1| epoxide hydrolase EphF [Mycobacterium tuberculosis EAS054]
Length=151

 Score =  303 bits (777),  Expect = 1e-80, Method: Compositional matrix adjust.
 Identities = 151/151 (100%), Positives = 151/151 (100%), Gaps = 0/151 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG
Sbjct  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
            NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR
Sbjct  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRF  151
            HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRF
Sbjct  121  HPEKVTGFFGVNTVAPWVKRDLGMLRNMWRF  151


>gi|289747901|ref|ZP_06507279.1| epoxide hydrolase ephF [Mycobacterium tuberculosis 02_1987]
 gi|289688429|gb|EFD55917.1| epoxide hydrolase ephF [Mycobacterium tuberculosis 02_1987]
 gi|339296845|gb|AEJ48955.1| epoxide hydrolase ephF [Mycobacterium tuberculosis CCDC5180]
Length=130

 Score =  257 bits (656),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 128/128 (100%), Positives = 128/128 (100%), Gaps = 0/128 (0%)

Query  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60
            MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG
Sbjct  1    MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADG  60

Query  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120
            NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR
Sbjct  61   NRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLR  120

Query  121  HPEKVTGF  128
            HPEKVTGF
Sbjct  121  HPEKVTGF  128


>gi|284045647|ref|YP_003395987.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684]
 gi|283949868|gb|ADB52612.1| alpha/beta hydrolase fold protein [Conexibacter woesei DSM 14684]
Length=291

 Score =  209 bits (533),  Expect = 3e-52, Method: Compositional matrix adjust.
 Identities = 111/292 (39%), Positives = 171/292 (59%), Gaps = 4/292 (1%)

Query  2    IALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGN  61
            + LP +EG+ HR V V  G+R+HVA+ GP D P V+L+HG+PQ+WW WRD++  LA D +
Sbjct  3    LPLPQVEGITHRDVTV-RGIRLHVAEGGPQDAPPVLLLHGWPQHWWMWRDVLVDLARD-H  60

Query  62   RVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRH  121
            RV+ PDLRG GWS APR  Y K E+ADD  A+LD LG+ +V L+ HDWG    F++ L  
Sbjct  61   RVIAPDLRGLGWSDAPRRGYVKQELADDNIALLDALGLDRVDLIGHDWGAFTGFLICLTA  120

Query  122  PEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGW  181
            PE++  F G +    W  R+   LR + + WYQ+ ++ P +G  ++   +G   R +   
Sbjct  121  PERIGHFLGCSIPHIWPPRERPSLRRLSQLWYQVVLAAPGVGQGLMR--QGELTRKVLTA  178

Query  182  VGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWL  241
                 R  D ++  ++  +++P HA A +++YR+F   E+     G ++D  +      L
Sbjct  179  ARTHGRYSDYELEQFVSVLKQPEHALASAQYYRSFLLHELKPLASGAFHDRPLSTKTLLL  238

Query  242  HGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
             GT DP++     D +   A + E+E V   GH++ E+RP LV++R RA  A
Sbjct  239  WGTDDPILRGAKTDEHRAFAPEMEIERVPDTGHFLPEERPGLVVERARALFA  290


>gi|169631596|ref|YP_001705245.1| epoxide hydrolase EphF [Mycobacterium abscessus ATCC 19977]
 gi|169243563|emb|CAM64591.1| Possible epoxide hydrolase EphF [Mycobacterium abscessus]
Length=290

 Score =  189 bits (480),  Expect = 4e-46, Method: Compositional matrix adjust.
 Identities = 109/291 (38%), Positives = 161/291 (56%), Gaps = 9/291 (3%)

Query  3    ALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNR  62
            ++P L+GVEH++V   + V+IHVA AGP DG AV+L+HG+P+NWW W  +I  LAA G R
Sbjct  5    SMPVLDGVEHQYVQAGD-VKIHVAVAGPQDGRAVVLLHGWPENWWMWHKVIPALAAAGYR  63

Query  63   VLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHP  122
            V   DLRGAGWS    + Y K + A D+ A  D LG+    LV HDWGG  A ++ L+  
Sbjct  64   VHAMDLRGAGWSEVAPAGYEKEQFASDVLAAADALGLESFDLVGHDWGGWTAQLVALKAQ  123

Query  123  EKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWV  182
             ++     +N    W ++   + R   +  YQ+ +  PV+GP     P   +F   +G  
Sbjct  124  SRIRRLVVLNIPPVW-QQPGRVARYAHKLAYQLVVGAPVVGPLSHLSPTLWWFIRRSG--  180

Query  183  GGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLH  242
                 +P + V  +  C R+     AGS+ YR+   +E     RG Y+D ++ +PVR L 
Sbjct  181  -----MPKESVDFFRSCFRDRDRRVAGSKIYRSMVGKEFANLARGPYDDQKLTMPVRVLF  235

Query  243  GTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            G  D  + P LLDG+ + A D  +  V   GH+IV+++PELV+  +   LA
Sbjct  236  GLDDVAVHPSLLDGFKDHADDLNITEVPNCGHFIVDEQPELVVKWLSEVLA  286


>gi|311896903|dbj|BAJ29311.1| putative hydrolase [Kitasatospora setae KM-6054]
Length=318

 Score =  180 bits (457),  Expect = 2e-43, Method: Compositional matrix adjust.
 Identities = 113/290 (39%), Positives = 148/290 (52%), Gaps = 3/290 (1%)

Query  4    LPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRV  63
            +PAL GV H+  +V  G+R+H ADAGPAD P V+LVHGFPQ+W+ WR ++ PL A   R+
Sbjct  1    MPALAGVRHQVAEVG-GLRLHYADAGPADAPPVLLVHGFPQHWYAWRRVV-PLLAGDFRL  58

Query  64   LCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPE  123
            LC DL G GWS     R++    A DL   LD L +    L+AHDWG    F+   R PE
Sbjct  59   LCLDLPGFGWSEGAPDRWSTAARAADLVGFLDALELESAALLAHDWGAWAGFLACARWPE  118

Query  124  KVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVG  183
            +      +N V  W +R    L   WRFWY + +  P +G  V+         LL   + 
Sbjct  119  RFDAHLALNMVHLWPERR-DTLACAWRFWYTLALEWPPVGRTVLRHWPAFTRHLLRRGLV  177

Query  184  GGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHG  243
                +   ++  Y    REP  A AG   +R F   ++    R E++  R+  P   L G
Sbjct  178  DRSALDPAELAEYAGAAREPLAALAGESVHRAFVADDLGALRRKEFHALRLPTPTLVLAG  237

Query  244  TGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
              DPVI P LL G AE   D  VE V   GH +  +RPELV  R RA  A
Sbjct  238  GRDPVIPPRLLSGGAEFCDDLRVETVPDTGHQLPAERPELVAARARALFA  287


>gi|256395267|ref|YP_003116831.1| alpha/beta hydrolase fold protein [Catenulispora acidiphila DSM 
44928]
 gi|256361493|gb|ACU74990.1| alpha/beta hydrolase fold protein [Catenulispora acidiphila DSM 
44928]
Length=294

 Score =  178 bits (452),  Expect = 7e-43, Method: Compositional matrix adjust.
 Identities = 110/284 (39%), Positives = 159/284 (56%), Gaps = 7/284 (2%)

Query  10   VEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLR  69
            + HR V  A GVR H+A++GPADG  ++L+HGFPQ+W+ WR ++  LAA  +RVL  DLR
Sbjct  16   LTHRFV-TARGVRFHIAESGPADGTPLVLLHGFPQHWYVWRHVLPHLAAT-HRVLALDLR  73

Query  70   GAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFF  129
            G GWS A    Y+   +A+D+ AVLD LG+ +  +V HDWGG V F+  LRHPE++    
Sbjct  74   GCGWSEATEHGYSTGNLAEDVIAVLDALGIDRAAVVGHDWGGWVGFVAALRHPERIRALA  133

Query  130  GVNTVAPW-VKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRV  188
             VN    W ++R   +L N+WR W+   +  P IG R++    G    LL  W G     
Sbjct  134  SVNMTHLWPIQRR--VLPNLWRMWHTAFIEHPPIG-RLVLRHTGFAGFLLRHWSGDPTLW  190

Query  189  PDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPV  248
              +D R+Y D +R+P  A A  +    +  RE+     G Y  AR+ VP   + G  D V
Sbjct  191  EREDPRIYTDLLRDPARARAVEQVNAAYVWREIFGHPLGRYRKARLSVPTLIIGGERDVV  250

Query  249  ITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            I P +L+G    A +  V ++ G GH + E++P  V + +  FL
Sbjct  251  IPPAVLEGGERHADELAVVVLPG-GHLLPEEQPSAVAEELLRFL  293


>gi|317509219|ref|ZP_07966840.1| alpha/beta hydrolase [Segniliparus rugosus ATCC BAA-974]
 gi|316252429|gb|EFV11878.1| alpha/beta hydrolase [Segniliparus rugosus ATCC BAA-974]
Length=290

 Score =  165 bits (418),  Expect = 7e-39, Method: Compositional matrix adjust.
 Identities = 110/291 (38%), Positives = 158/291 (55%), Gaps = 11/291 (3%)

Query  4    LPALEGVEHRHVDVAEGVRIHVADAGPADGP--AVMLVHGFPQNWWEWRDLIGPLAADGN  61
            +P L GVEHR V+ A+G+R H+A+AG AD P  AV+LVHGFPQ+WW WR ++ PL A+  
Sbjct  1    MPDLPGVEHRWVE-ADGIRFHIAEAG-ADRPGKAVVLVHGFPQHWWTWRGVL-PLLAEHR  57

Query  62   RVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRH  121
            R +  DLRG GWS AP + Y K   A D+ AV++ LG+ K  LV HDWGG  + +  +  
Sbjct  58   RAVALDLRGYGWSEAPAAGYDKKTFAKDIVAVVEALGLDKPVLVGHDWGGWSSLVAAVLR  117

Query  122  PEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLL-TG  180
            PE  T    V   APWV+  +   R     +  I  S   +GP +I     R+ RLL T 
Sbjct  118  PEVFTAVASVAVPAPWVQ--MPAKRPSILLYQNILGS--GLGPWIIRSGNQRFLRLLFTR  173

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
                G R  +++  ++L+  REP  A AGS  YRTF   E  + + G Y      +P   
Sbjct  174  GTAPGSRN-EENFEVFLERFREPARARAGSATYRTFVRDEWPQLVSGGYLPGPAPIPTLL  232

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAF  291
            + G+ D ++    +   A   +D +   +D   HW+ E++PE +  R+ AF
Sbjct  233  VRGSRDQLLGERAMRRAARDGADIDFHTIDEATHWLPEEQPEALAGRLLAF  283


>gi|304570623|ref|YP_830541.2| alpha/beta hydrolase fold [Arthrobacter sp. FB24]
Length=300

 Score =  162 bits (409),  Expect = 8e-38, Method: Compositional matrix adjust.
 Identities = 95/296 (33%), Positives = 149/296 (51%), Gaps = 6/296 (2%)

Query  3    ALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNR  62
            A+P L+GV HR +DV  G+ +H+A+AG  +G  + L+HGFPQ+WWEW  +I P  A+  R
Sbjct  7    AMPQLDGVTHRWIDV-RGITMHIAEAG--NGEPIFLLHGFPQHWWEWHGVI-PRLAEHYR  62

Query  63   VLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHP  122
            V+  D RG GW+ AP   Y    + +D+  ++D L + + + + HDWG  VA ++ +  P
Sbjct  63   VIAVDQRGFGWTDAPADGYNARTLIEDIVLLMDELDIPRARFLTHDWGSVVAQLLAMERP  122

Query  123  EKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWV  182
            + V            ++ + G+L    + W+   ++ PVIGPR+  + K           
Sbjct  123  DLVEALVVTGAPDVHIRPNAGLLGLFPKLWHAFALAAPVIGPRLQRNEKFTRHLFTAFEP  182

Query  183  GGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLH  242
             GG  VP++D+ LY   M +P  A AGS  YR       +  + G Y      VP   L 
Sbjct  183  AGG--VPEEDMELYAVGMAQPERARAGSALYRGTILPAFMGIIFGAYAKRDFTVPTLALI  240

Query  243  GTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQ  298
            G  +P  T   +     R  +   E++ G GH++ + RPEL+ DR   F     +Q
Sbjct  241  GDREPSATLQEMGHRPGRGGNVTTEILPGEGHFLADHRPELIADRALRFFGHAPDQ  296


>gi|315442997|ref|YP_004075876.1| hydrolase or acyltransferase of alpha/beta superfamily [Mycobacterium 
sp. Spyr1]
 gi|315261300|gb|ADT98041.1| predicted hydrolase or acyltransferase of alpha/beta superfamily 
[Mycobacterium sp. Spyr1]
Length=293

 Score =  160 bits (405),  Expect = 2e-37, Method: Compositional matrix adjust.
 Identities = 102/281 (37%), Positives = 152/281 (55%), Gaps = 11/281 (3%)

Query  5    PALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVL  64
            P + GV  RH     GV  H+ +AGP DG  V+ +HG+PQ+ W +RDL+G     G R++
Sbjct  6    PPIAGVR-RHRVTVRGVDFHITEAGPEDGRPVLALHGWPQHHWAYRDLLGD-PPPGLRII  63

Query  65   CPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEK  124
             PDL G GWS  P  R+ K ++  DL A++D LG+ +  LV HDWGG +  ++ LR PE+
Sbjct  64   APDLPGYGWSGPPSHRWAKEDVVTDLVALVDALGLDRFLLVGHDWGGYIGHLLALRIPER  123

Query  125  VTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGG  184
            +  +  +N   PWV   + M  ++WRF    P+   V    V    + RY   +  +   
Sbjct  124  IDAYLALNIAHPWVPPKV-MAPHLWRFLLYQPV---VASAGVPLQTRTRYLEKVV-FRAA  178

Query  185  GFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLR-GEYNDARVDVPVRWLHG  243
              ++    V  Y +  R+P  A      YRTF TRE+ + +R GE   +   VP R L G
Sbjct  179  APKLDAATVGTYAERFRDPVVARTARDTYRTFLTREIPKGVRDGERRWS--TVPTRVLFG  236

Query  244  TGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELV  284
              D  I PDL      RA D+ +++VDG GH+I++++P+LV
Sbjct  237  RSDTAIHPDLAAAETARADDYTIDVVDG-GHFILDEQPDLV  276


>gi|256833681|ref|YP_003162408.1| alpha/beta hydrolase fold protein [Jonesia denitrificans DSM 
20603]
 gi|256687212|gb|ACV10105.1| alpha/beta hydrolase fold protein [Jonesia denitrificans DSM 
20603]
Length=324

 Score =  159 bits (403),  Expect = 3e-37, Method: Compositional matrix adjust.
 Identities = 99/297 (34%), Positives = 150/297 (51%), Gaps = 4/297 (1%)

Query  4    LPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRV  63
             P + GVEH  +D+    R+HVA AG      ++L+HGFPQNWWEWR++I PLA     V
Sbjct  22   FPDMTGVEHWMLDLPT-TRLHVAFAGDPHAQPLILLHGFPQNWWEWREVIAPLA-QHYWV  79

Query  64   LCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPE  123
            + PDLRGAGWS APR  Y+    A D+ A++D + + +  LV HD+G  + + +      
Sbjct  80   IVPDLRGAGWSDAPRQGYSAEHHARDIIALMDVMSIKRAALVTHDYGALIGYHLTDTRAP  139

Query  124  KVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRY-FRLLTGWV  182
            + T    ++   P +      L   WR WYQI M LP +GP ++S  K R+   LL  + 
Sbjct  140  RFTHHIAMSAPPPALTTHSRWLGETWRSWYQIIMWLPGLGPALLSGGKQRFATHLLEAYS  199

Query  183  GGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLH  242
                     D  ++L  ++   +A A S+ +R     E  R +R    D RV VP   L 
Sbjct  200  AYPEVWSATDRAMFLTPLKRAANARAMSKVHRHLIHPETRRRMRNARTDQRVSVPTTLLV  259

Query  243  GTGDPVITPDLLDGYAE-RASDFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQ  298
            G  DP++   +  GY E R  +  V++V    H++V+ +   V   +   L+   E+
Sbjct  260  GELDPLVGAMVRHGYTEGRDPNVSVKVVPDASHYVVDDQSVSVATIITTTLSTAQER  316


>gi|120405714|ref|YP_955543.1| alpha/beta hydrolase fold protein [Mycobacterium vanbaalenii 
PYR-1]
 gi|119958532|gb|ABM15537.1| alpha/beta hydrolase fold protein [Mycobacterium vanbaalenii 
PYR-1]
Length=300

 Score =  157 bits (397),  Expect = 2e-36, Method: Compositional matrix adjust.
 Identities = 106/306 (35%), Positives = 158/306 (52%), Gaps = 27/306 (8%)

Query  5    PALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIG--PLAA----  58
            P ++GV  RH   A GV  HV +AGP DG  V+ +HG+PQ+ W +R L+   P +A    
Sbjct  6    PPIDGVR-RHFVTARGVNFHVTEAGPEDGRPVLALHGWPQHHWVYRSLLADPPTSAGASS  64

Query  59   ----DGNRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVA  114
                 G R++ PDL G GWS     ++ K ++  DL A++D +G+ +V L+ HDWGG + 
Sbjct  65   RLPEPGLRIIAPDLPGYGWSGPAPHKWAKEDVVSDLVALMDAMGLDRVLLIGHDWGGYIG  124

Query  115  FIMMLRHPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRY  174
             ++ +R PE++ G+  +N   PWV   + M  ++WRF    P+            P  R+
Sbjct  125  HLLAMRVPERIDGYLALNIAHPWVPPKV-MAPHLWRFLQYQPLVA------FAGVPLQRH  177

Query  175  FRLLT-GWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLR-GEYNDA  232
               L   +     ++    VR+Y +  R+P  A      YRTF  RE    +R GE    
Sbjct  178  TSFLKRAYKLAAPKLDPQTVRVYSERFRDPVVARTARDTYRTFLLREAPAAIRNGERR--  235

Query  233  RVDVPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            R  VP R L G  D  I P L      RA D+ +++VDG GH+I++++PEL    VRA L
Sbjct  236  RSKVPTRALFGRDDAAIHPSLAAAETARADDYTIDVVDG-GHFILDEQPEL----VRAKL  290

Query  293  AAGTEQ  298
             A  E+
Sbjct  291  IALAEE  296


>gi|145222550|ref|YP_001133228.1| alpha/beta hydrolase fold protein [Mycobacterium gilvum PYR-GCK]
 gi|145215036|gb|ABP44440.1| alpha/beta hydrolase fold protein [Mycobacterium gilvum PYR-GCK]
Length=278

 Score =  155 bits (393),  Expect = 6e-36, Method: Compositional matrix adjust.
 Identities = 97/266 (37%), Positives = 146/266 (55%), Gaps = 10/266 (3%)

Query  20   GVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGWSSAPRS  79
            GV  H+ +AGP DG  V+ +HG+PQ+ W +RDL+G     G R++ PDL G GWS  P  
Sbjct  5    GVDFHITEAGPEDGRPVLALHGWPQHHWAYRDLLGD-PPPGLRIIAPDLPGYGWSGPPPH  63

Query  80   RYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTVAPWVK  139
            R+ K ++  DL A++D LG+ +  LV HDWGG +  ++ LR PE++  +  +N   PWV 
Sbjct  64   RWAKEDVVTDLVALVDALGLDRFLLVGHDWGGYIGHLLALRIPERIDAYLALNIAHPWVP  123

Query  140  RDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPDDDVRLYLDC  199
              + M  ++WRF    P+   V    V    + RY   +  +     ++    V  Y + 
Sbjct  124  PKV-MAPHLWRFLLYQPV---VASAGVPLQTRTRYLEKVV-FRAAAPKLDAATVGTYAER  178

Query  200  MREPGHAEAGSRWYRTFQTREMLRWLR-GEYNDARVDVPVRWLHGTGDPVITPDLLDGYA  258
             R+P  A      YRTF TRE+ + +R GE   +   VP R L G  D  I PDL     
Sbjct  179  FRDPVVARTARDTYRTFLTREIPKGVRDGERRWS--TVPTRVLFGRSDTAIHPDLAAAET  236

Query  259  ERASDFEVELVDGVGHWIVEQRPELV  284
             RA D+ +++VDG GH+I++++P+LV
Sbjct  237  ARADDYTIDVVDG-GHFILDEQPDLV  261


>gi|116609717|gb|ABK02441.1| alpha/beta hydrolase fold protein [Arthrobacter sp. FB24]
Length=275

 Score =  146 bits (369),  Expect = 4e-33, Method: Compositional matrix adjust.
 Identities = 85/276 (31%), Positives = 135/276 (49%), Gaps = 5/276 (1%)

Query  23   IHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGWSSAPRSRYT  82
            +H+A+AG  +G  + L+HGFPQ+WWEW  +I P  A+  RV+  D RG GW+ AP   Y 
Sbjct  1    MHIAEAG--NGEPIFLLHGFPQHWWEWHGVI-PRLAEHYRVIAVDQRGFGWTDAPADGYN  57

Query  83   KTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTVAPWVKRDL  142
               + +D+  ++D L + + + + HDWG  VA ++ +  P+ V            ++ + 
Sbjct  58   ARTLIEDIVLLMDELDIPRARFLTHDWGSVVAQLLAMERPDLVEALVVTGAPDVHIRPNA  117

Query  143  GMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPDDDVRLYLDCMRE  202
            G+L    + W+   ++ PVIGPR+  + K            GG  VP++D+ LY   M +
Sbjct  118  GLLGLFPKLWHAFALAAPVIGPRLQRNEKFTRHLFTAFEPAGG--VPEEDMELYAVGMAQ  175

Query  203  PGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVITPDLLDGYAERAS  262
            P  A AGS  YR       +  + G Y      VP   L G  +P  T   +     R  
Sbjct  176  PERARAGSALYRGTILPAFMGIIFGAYAKRDFTVPTLALIGDREPSATLQEMGHRPGRGG  235

Query  263  DFEVELVDGVGHWIVEQRPELVLDRVRAFLAAGTEQ  298
            +   E++ G GH++ + RPEL+ DR   F     +Q
Sbjct  236  NVTTEILPGEGHFLADHRPELIADRALRFFGHAPDQ  271


>gi|311743374|ref|ZP_07717181.1| possible epoxide hydrolase EphF [Aeromicrobium marinum DSM 15272]
 gi|311313442|gb|EFQ83352.1| possible epoxide hydrolase EphF [Aeromicrobium marinum DSM 15272]
Length=301

 Score =  145 bits (366),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 103/306 (34%), Positives = 156/306 (51%), Gaps = 22/306 (7%)

Query  3    ALPALEGVEHRHVDVAEGVRIHVADAGP----ADG-PAVMLVHGFPQNWWEWRDLIGPLA  57
            A P L GV HR V V +GVR+HVA+AG      DG P+++LVHG+PQ+WW W  +I PL 
Sbjct  6    APPDLPGVAHRWVTV-DGVRLHVAEAGTEHRDVDGRPSLVLVHGWPQHWWCWHRVI-PLL  63

Query  58   ADGNRVLCPDLRGAGWSSAP---RSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVA  114
            A  + V+  DLRG GWS  P      Y K   ADD+  ++  + + +  ++ HDWG   A
Sbjct  64   ARTHHVVAVDLRGHGWSDVPAPGHGNYDKRRFADDVIGLIGAMDLDRPVVIGHDWGAWTA  123

Query  115  FIMMLRHPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRY  174
             ++  R P    G      +APW         +MWRF YQ+    P     ++    G+ 
Sbjct  124  LLVAGRAPGLTRGVVATAIIAPWTDIP---TTDMWRFLYQVAAGGP--WGSLVHRAFGKA  178

Query  175  FRLLTGWVGGGFR----VPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYN  230
            F      +G   R      ++DV  YL+   +P    AG   Y TF   E     +G Y 
Sbjct  179  FLRTVYKLGSHGRREHVAGENDV--YLERYDDPARRAAGRSVYGTFLRAEFPAVAKGTYQ  236

Query  231  DARVDVPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRA  290
                DVP+ +L G GD ++ P +++     A +  +E ++G GHW+ E++PE ++++++ 
Sbjct  237  APVTDVPIIFLPGRGDAILVPRIVE-RGVVADNMSMETIEGAGHWVPEEQPEKLVEKIQE  295

Query  291  FLAAGT  296
            FLA  T
Sbjct  296  FLAGLT  301


>gi|163853241|ref|YP_001641284.1| alpha/beta hydrolase fold protein [Methylobacterium extorquens 
PA1]
 gi|163664846|gb|ABY32213.1| alpha/beta hydrolase fold [Methylobacterium extorquens PA1]
Length=288

 Score =  145 bits (366),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 99/292 (34%), Positives = 143/292 (49%), Gaps = 19/292 (6%)

Query  9    GVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDL  68
             V HRH+D+  G+R+HVA+AGPADG   +L+HGFP+ W+ WR  IGPLA  G R+L PD 
Sbjct  5    AVSHRHIDL-RGLRLHVAEAGPADGVPTILLHGFPEFWFGWRHQIGPLAGSGLRLLIPDQ  63

Query  69   RGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVT  126
            RG G S  P+  + Y    +A D+ A+ D  G+A+  LV HDWGG VAF +   HPE+V 
Sbjct  64   RGYGLSDRPKGIAAYHLDRLAQDVIALADACGLARFNLVGHDWGGLVAFWVASFHPERVE  123

Query  127  GFFGVNTV-----APWVKRDLGM-LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
                +N        P+++R  G  LR+ +  ++Q    LP++  RV++  +GR  R L  
Sbjct  124  RLAALNACHPGVFGPYLRRHPGQALRSAYAGFFQ----LPLLPERVLTAREGRLLRALMR  179

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
                     + D+ +Y      PG   A   WYR       L  L  E +  +V  P   
Sbjct  180  RSSAPGSFTEADLDVYAREWLRPGAVTAMLNWYRA------LAQLPRERHPPKVAAPTLI  233

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            L G  D  +   L +   +      ++      HW+    PE V   +  FL
Sbjct  234  LWGERDQALQTGLAEASLDLCERGRLQRFPQATHWVQHDAPEAVNAALIDFL  285


>gi|240140648|ref|YP_002965128.1| alpha/beta hydrolase, epoxide hydrolase [methylobacterium extorquens 
AM1]
 gi|240010625|gb|ACS41851.1| putative alpha/beta hydrolase, putative epoxide hydrolase [Methylobacterium 
extorquens AM1]
Length=288

 Score =  145 bits (365),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 98/292 (34%), Positives = 143/292 (49%), Gaps = 19/292 (6%)

Query  9    GVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDL  68
             V HRH+D+  G+R+HVA+AGPADG   +L+HGFP+ W+ WR  IGPLA  G R+L PD 
Sbjct  5    AVSHRHIDL-RGLRLHVAEAGPADGVPTILLHGFPEFWFGWRHQIGPLAGSGLRLLIPDQ  63

Query  69   RGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVT  126
            RG G S  P+  + Y    +A D+ A+ D  G+A+  LV HDWGG VAF +   HPE+V 
Sbjct  64   RGYGLSDRPKGIAAYHLDRLAQDVIALADACGLARFNLVGHDWGGLVAFWVASFHPERVE  123

Query  127  GFFGVNTV-----APWVKRDLGM-LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
                +N        P+++R  G  LR+ +  ++Q    LP++  RV++  +GR  R L  
Sbjct  124  RLAALNACHPGVFGPYLRRHPGQALRSAYAGFFQ----LPLLPERVLTAREGRLLRALMR  179

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
                     + D+ +Y      PG   A   WYR       L  L  E +  ++  P   
Sbjct  180  RSSAPGSFTEADLDVYAREWLRPGAVTAMLNWYRA------LAQLPRERHPPKIAAPTLI  233

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            L G  D  +   L +   +      ++      HW+    PE V   +  FL
Sbjct  234  LWGERDQALQTGLAEASLDLCERGRLQRFPQATHWVQHDAPEAVNAALIDFL  285


>gi|254563162|ref|YP_003070257.1| alpha/beta hydrolase [Methylobacterium extorquens DM4]
 gi|254270440|emb|CAX26440.1| putative alpha/beta hydrolase, putative epoxide hydrolase [Methylobacterium 
extorquens DM4]
Length=288

 Score =  144 bits (364),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 98/292 (34%), Positives = 143/292 (49%), Gaps = 19/292 (6%)

Query  9    GVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDL  68
             V HRH+D+  G+R+HVA+AGPADG   +L+HGFP+ W+ WR  IGPLA  G R+L PD 
Sbjct  5    AVSHRHIDL-RGLRLHVAEAGPADGVPTILLHGFPEFWFGWRHQIGPLAGSGLRLLIPDQ  63

Query  69   RGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVT  126
            RG G S  P+  + Y    +A D+ A+ D  G+A+  LV HDWGG VAF +   HPE+V 
Sbjct  64   RGYGLSDRPKGIAAYHLDRLAQDVIALADACGLARFNLVGHDWGGLVAFWVASFHPERVE  123

Query  127  GFFGVNTV-----APWVKRDLGM-LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
                +N        P+++R  G  LR+ +  ++Q    LP++  RV++  +GR  R L  
Sbjct  124  RLAALNACHPGVFGPYLRRHPGQALRSAYAGFFQ----LPLLPERVLTAREGRLLRALMR  179

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
                     + D+ +Y      PG   A   WYR       L  L  E +  ++  P   
Sbjct  180  RSSAPGSFTEADLDVYAREWLRPGAVSAMLNWYRA------LAQLPRERHPPKIVAPTLI  233

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            L G  D  +   L +   +      ++      HW+    PE V   +  FL
Sbjct  234  LWGERDQALQTGLAEASLDLCERGRLQRFPQATHWVQHDAPEAVNAALIDFL  285


>gi|218532056|ref|YP_002422872.1| alpha/beta hydrolase fold protein [Methylobacterium chloromethanicum 
CM4]
 gi|218524359|gb|ACK84944.1| alpha/beta hydrolase fold protein [Methylobacterium chloromethanicum 
CM4]
Length=288

 Score =  143 bits (361),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 97/292 (34%), Positives = 143/292 (49%), Gaps = 19/292 (6%)

Query  9    GVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDL  68
             V HRH+D+  G+R+HVA+AGPADG   +++HGFP+ W+ WR  IGPLA  G R+L PD 
Sbjct  5    AVSHRHIDL-RGLRLHVAEAGPADGVPTIMLHGFPEFWFGWRHQIGPLAGSGLRLLIPDQ  63

Query  69   RGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVT  126
            RG G S  P+  + Y    +A D+ A+ D  G+A+  LV HDWGG VAF +   HPE+V 
Sbjct  64   RGYGLSDRPKGIAAYHLDRLAQDVIALADACGLARFNLVGHDWGGLVAFWVASFHPERVE  123

Query  127  GFFGVNTV-----APWVKRDLGM-LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
                +N        P+++R  G  LR+ +  ++Q    LP++  RV++  +GR  R L  
Sbjct  124  RLAALNACHPGVFGPYLRRHPGQALRSAYAGFFQ----LPLLPERVLTAREGRLLRALMR  179

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
                     + D+ +Y      PG   A   WYR       L  L  E +  ++  P   
Sbjct  180  RSSAPGSFTEADLDVYAREWLRPGAVTAMLNWYRA------LAQLPRERHPPKIVAPTLI  233

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            L G  D  +   L +   +      ++      HW+    PE V   +  FL
Sbjct  234  LWGERDQALQAGLAEASLDLCERGRLQRFPQATHWVQHDAPEAVNAALIDFL  285


>gi|298246057|ref|ZP_06969863.1| alpha/beta hydrolase fold protein [Ktedonobacter racemifer DSM 
44963]
 gi|297553538|gb|EFH87403.1| alpha/beta hydrolase fold protein [Ktedonobacter racemifer DSM 
44963]
Length=290

 Score =  136 bits (343),  Expect = 3e-30, Method: Compositional matrix adjust.
 Identities = 83/284 (30%), Positives = 137/284 (49%), Gaps = 7/284 (2%)

Query  11   EHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRG  70
            +HR + +  G+R+H    G  +G  ++L+HGFP+ W+ WR  I  LA  G +V+ PDLRG
Sbjct  9    QHRDI-LTNGIRMHYVTQG--EGSLIVLLHGFPEFWYSWRHQIPFLAQLGYKVVAPDLRG  65

Query  71   AGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFG  130
               +  PR  Y    +  D+  ++ GLG  +  +V HDWGG + +   LR+P  V    G
Sbjct  66   YNDTDKPRRGYEIATLLRDIEGLIKGLGYERAIVVGHDWGGVLMWQFGLRYPHMVERLIG  125

Query  131  VNTVAPWV-KRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYF-RLLTGWVGGGFRV  188
            +N   PW   R+L   + + + WY     LP++    +S        ++L          
Sbjct  126  LNAPPPWTFARELRTWKQLRKSWYVYAFQLPILPELALSREGAEPIAKMLYASAVQKSAF  185

Query  189  PDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPV  248
            P+D +  Y + M +PG   A   +YR+   R  +  + G  N  R+D P   + G  D  
Sbjct  186  PEDVLERYKEAMSKPGALTAAINYYRSIWRRSSIGAVSG--NKGRIDKPTLLIWGEQDVA  243

Query  249  ITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            +   +  G  E   + EV  +   GHW+ +++P+LV + +  FL
Sbjct  244  LDIAMTYGLEEWVPNIEVRRIPDSGHWVQQEKPDLVNEWIADFL  287


>gi|288556239|ref|YP_003428174.1| putative hydrolase [Bacillus pseudofirmus OF4]
 gi|288547399|gb|ADC51282.1| putative hydrolase [Bacillus pseudofirmus OF4]
Length=283

 Score =  136 bits (343),  Expect = 4e-30, Method: Compositional matrix adjust.
 Identities = 87/284 (31%), Positives = 136/284 (48%), Gaps = 20/284 (7%)

Query  18   AEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGWSSAP  77
              G+++H A AGP DGP V+L+HGFP+ W+ WR+ + PL   G RV+ PD RG   S  P
Sbjct  11   TNGIKLHTAVAGPEDGPLVILLHGFPEFWYGWRNQVEPLVQAGYRVVIPDQRGYNLSEKP  70

Query  78   R--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTVA  135
                 YT   + DD+  ++D LG  K  ++ HDWGG VA+ +    P+ V     +N+  
Sbjct  71   LEIKEYTIDHLRDDITGIIDYLGYKKATIIGHDWGGIVAWHLASTKPDYVDKLMVINSPH  130

Query  136  PWV------KRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVP  189
            P V      K  L +LR+M+  ++Q+P  LP     ++S       + +           
Sbjct  131  PAVFKSTILKDPLQLLRSMYMMFFQLP-KLP---ETLLSQNDYESVKKVLMQTSLPDTFT  186

Query  190  DDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVI  249
            D ++  Y+   ++P        WYR   TR  L         + + +PV+ L G  D  +
Sbjct  187  DQELSKYMQAWQQPNALTTMLNWYRAM-TRTPLN------KPSALQMPVKVLWGQKDTFL  239

Query  250  TPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            T  L    A    + E+ ++DG  HW+  ++ ELV   +  FLA
Sbjct  240  TSQLAKDSAALCDNAELIMIDGT-HWVHLEKSELVNSMIGKFLA  282


>gi|294506178|ref|YP_003570236.1| alpha/beta hydrolase [Salinibacter ruber M8]
 gi|294342506|emb|CBH23284.1| alpha/beta hydrolase superfamily [Salinibacter ruber M8]
Length=296

 Score =  134 bits (338),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 94/280 (34%), Positives = 132/280 (48%), Gaps = 16/280 (5%)

Query  13   RHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAG  72
            RH    EGVR+HV  AGP DGP V+L+HGFP+ W+ WR  I  LAA G+RV+ PD RG  
Sbjct  15   RHWVDREGVRLHVRAAGPEDGPLVVLLHGFPEFWYGWRRQIPALAAAGHRVVVPDQRGYN  74

Query  73   WSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFG  130
             S APR  + Y    + DD+ AV+D  G A+  +V HDWG  VA+ +    PE++     
Sbjct  75   RSDAPRAVAAYDLDRLVDDVCAVIDATGRARASVVGHDWGAMVAWHLAHARPERLRRLAV  134

Query  131  VNTVAPWVKRD------LGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGG  184
            +N   P V RD        +LR+ +  ++Q+P  LP     ++    G+    +  W G 
Sbjct  135  LNVPHPHVFRDTLRTSPTQLLRSTYALFFQVP-GLPEW---LLGRNDGQGLATMLRWSGR  190

Query  185  GFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGT  244
                 D D+  Y    R PG       WYR    R     LR       VDVP   + G 
Sbjct  191  PDTFADADLAAYRRAWRRPGRLRGMLNWYRAAGRRA----LRSTPPSGAVDVPALVVWGA  246

Query  245  GDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELV  284
             D  ++  +    A   +D  + ++D   HW+    P  V
Sbjct  247  QDIALSRQMAAPSAAMCADGRLRIIDDATHWVQHDAPATV  286


>gi|83815536|ref|YP_444434.1| alpha/beta fold family hydrolase [Salinibacter ruber DSM 13855]
 gi|83756930|gb|ABC45043.1| hydrolase, alpha/beta fold family, putative [Salinibacter ruber 
DSM 13855]
Length=296

 Score =  134 bits (337),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 92/274 (34%), Positives = 130/274 (48%), Gaps = 16/274 (5%)

Query  19   EGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGWSSAPR  78
            EGVR+HV  AGP DGP V+L+HGFP+ W+ WR  I  LAA G+RV+ PD RG   S APR
Sbjct  21   EGVRLHVRAAGPEDGPLVVLLHGFPEFWYGWRRQIPALAAAGHRVVVPDQRGYNHSDAPR  80

Query  79   --SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTVAP  136
              + Y    + DD+ AV+D  G A+  +V HDWG  VA+ +    PE++     +N   P
Sbjct  81   AVAAYDLDRLVDDVCAVVDATGRARASVVGHDWGAMVAWHLAHARPERLRRLAVLNVPHP  140

Query  137  WVKRD------LGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPD  190
             V RD        +LR+ +  ++Q+P  LP     ++    G+    +  W G      D
Sbjct  141  HVFRDTLRTSPTQLLRSTYALFFQVP-GLPEW---LLGRNDGQGLATMLRWSGRPDTFAD  196

Query  191  DDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVIT  250
             D+  Y    R PG       WYR    R     LR       VDVP   + G  D  ++
Sbjct  197  ADLAAYRRAWRRPGRLRGMLNWYRAAGRRA----LRSTPPSGAVDVPALVVWGAQDIALS  252

Query  251  PDLLDGYAERASDFEVELVDGVGHWIVEQRPELV  284
              +    A   +D  + ++D   HW+    P  V
Sbjct  253  RQMAAPSAAMCADGRLRIIDDATHWVQHDAPATV  286


>gi|188583494|ref|YP_001926939.1| alpha/beta hydrolase fold protein [Methylobacterium populi BJ001]
 gi|179346992|gb|ACB82404.1| alpha/beta hydrolase fold [Methylobacterium populi BJ001]
Length=288

 Score =  132 bits (331),  Expect = 8e-29, Method: Compositional matrix adjust.
 Identities = 94/292 (33%), Positives = 135/292 (47%), Gaps = 19/292 (6%)

Query  9    GVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDL  68
               HRHVD+  G+R+H+A+AGPADGP  +L+HGFP++ + WR  IGPLA  G R+L PD 
Sbjct  5    AASHRHVDL-RGLRLHLAEAGPADGPPTILLHGFPESSYGWRHQIGPLAESGLRLLVPDQ  63

Query  69   RGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVT  126
            RG G S  P+  + Y    +A D+ A+ D  G  +  LV HDWGG VAF +   HPE+V 
Sbjct  64   RGYGLSDRPKGIAAYHLDRLAGDVIALADACGATRFNLVGHDWGGLVAFWVASFHPERVE  123

Query  127  GFFGVNTV-----APWVKRDLGM-LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTG  180
                +N        P+++R  G  LR+ +  ++QIP  LP    R+++  +    R L  
Sbjct  124  RLAVLNACHPGVFGPYLRRHPGQALRSAYAGFFQIP-GLP---ERLLTARRAHLLRELMR  179

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRW  240
                       D+  Y      PG   A   WYR        R      +  R+  P   
Sbjct  180  RSSRPDTFSAADLDTYARDWLRPGAVTAMLNWYRALAQLPRAR------HPPRITAPTLI  233

Query  241  LHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            L G  D  +   L +   +      ++      HW+    PE V   +  FL
Sbjct  234  LWGERDQALQSGLAEASLDLCERGRLQRFPQATHWVQHDAPEAVNAALIGFL  285


>gi|322371791|ref|ZP_08046334.1| alpha/beta hydrolase fold protein [Haladaptatus paucihalophilus 
DX253]
 gi|320548676|gb|EFW90347.1| alpha/beta hydrolase fold protein [Haladaptatus paucihalophilus 
DX253]
Length=306

 Score =  131 bits (329),  Expect = 1e-28, Method: Compositional matrix adjust.
 Identities = 93/286 (33%), Positives = 135/286 (48%), Gaps = 12/286 (4%)

Query  17   VAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGWSSA  76
            +  GVR+H  +AG  DGP V+L+HGFP+ W+ WR+ I  LAA G  V+ PD+RG   S  
Sbjct  23   IVNGVRLHYVEAG--DGPLVLLLHGFPEFWYSWREQIPALAAAGYHVVAPDMRGYNDSEK  80

Query  77   PR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTV  134
            P     Y   E+  D+  ++D  G     +V HDWGG VA+ + +  PE+V     +N  
Sbjct  81   PHGVDAYRTDELVADVTGLIDHFGEETAHVVGHDWGGAVAWQVGIDRPERVDKLAVLNAP  140

Query  135  APWVKRD-LGMLRNMWRFWYQIPMSLPVIGPRVISDPKG--RYFRLLTGWVGGGFRVPDD  191
             P   R+ L     + R WY     LP + P +    +G      + T          +D
Sbjct  141  HPGRFREVLRTPSQLRRSWYIFFFQLPWL-PELFLSARGYESIENIFTDTPTNPDAFTED  199

Query  192  DVRLYLDCMREPGHAEAGSRWYRTFQTREM---LRWLRGEYNDA-RVDVPVRWLHGTGDP  247
            DVR Y++   +PG       +YR    + +   LR L G  ND+  V VP   + GT D 
Sbjct  200  DVRRYVEAAAKPGALTGSINYYRALFRQSVPTQLRSLVGGSNDSFDVRVPTMLIWGTEDF  259

Query  248  VITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
             +  +L +G      D  +E + G  HW+   RPE V D +  F A
Sbjct  260  ALGNELTEGLDRWIPDLRIERLPGASHWVQNDRPERVSDLLVEFFA  305


>gi|170747053|ref|YP_001753313.1| alpha/beta hydrolase fold protein [Methylobacterium radiotolerans 
JCM 2831]
 gi|170653575|gb|ACB22630.1| alpha/beta hydrolase fold [Methylobacterium radiotolerans JCM 
2831]
Length=291

 Score =  130 bits (328),  Expect = 2e-28, Method: Compositional matrix adjust.
 Identities = 95/296 (33%), Positives = 143/296 (49%), Gaps = 24/296 (8%)

Query  7    LEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCP  66
            + GV+ R + + E V +HVA+AGP  GP ++L+HGFP++W+ WR  IGPLA  G R++ P
Sbjct  9    VAGVKFRRIALPE-VALHVAEAGPETGPPIILLHGFPESWYGWRHQIGPLAETGLRIIAP  67

Query  67   DLRGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEK  124
            D RG G S  P   + Y    +A D+ A+ D  G   V+LV HDWGG VA+ +  RHPE+
Sbjct  68   DQRGYGLSDKPAGIAAYHLDRLAGDVLALADACGAPAVRLVGHDWGGLVAWWVASRHPER  127

Query  125  VTGFFGVNTVAP-----WVKRDLGM-LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFR--  176
            +     +N   P     +++   G  LR+ +   +Q    LP +  R+++  + R  R  
Sbjct  128  IDRLAILNAPHPAVVGAYMRHHPGQWLRSTYVGLFQ----LPRLPERLLTADRCRALRRA  183

Query  177  LLTGWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDV  236
            L +    G F   + D+  Y+    +PG       WYR        R         RV V
Sbjct  184  LTSSSRPGAF--AEADLDHYVAAWLQPGAMTGMLNWYRALVQLPRAR-------PPRVRV  234

Query  237  PVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            PV  L G  D  + P L +         ++   +   HW+  + PE V   + AFL
Sbjct  235  PVLILWGRRDTALQPGLAEASLAYCDASQLRWYERASHWLAHEEPEAVNADLAAFL  290


>gi|312194226|ref|YP_004014287.1| alpha/beta hydrolase fold protein [Frankia sp. EuI1c]
 gi|311225562|gb|ADP78417.1| alpha/beta hydrolase fold protein [Frankia sp. EuI1c]
Length=307

 Score =  130 bits (328),  Expect = 2e-28, Method: Compositional matrix adjust.
 Identities = 105/303 (35%), Positives = 148/303 (49%), Gaps = 33/303 (10%)

Query  13   RHVDV-AEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGA  71
            RH DV A G R+HVA+ G   GP V+L+HGFPQ WW WR  +  LAA G RV+ PDLRG 
Sbjct  18   RHRDVSANGTRLHVAELG--QGPLVLLLHGFPQFWWAWRHQLVALAAAGYRVVAPDLRGY  75

Query  72   GWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAF--------------IM  117
            G S  P   Y    +ADD+A ++  LG     LV HDWGG  ++              ++
Sbjct  76   GASDKPPRGYDAFTLADDVAGLIRALGERDAVLVGHDWGGLASWTAAAVWPRQVRRIAVL  135

Query  118  MLRHPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRL  177
             + HP ++   + V+       R  G L     F +Q+P        ++++D   R    
Sbjct  136  GMPHPLRIRHEYAVD------PRGQG-LAGAHLFGFQLPWRPER---QLVADDAARVGGY  185

Query  178  LTGWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDA---RV  234
            L  W G GF   D+D R Y   MR PG A +   ++R +  R + R     +  A    V
Sbjct  186  LRAWGGPGFPSDDED-RRYRAAMRIPGVAHSSLEYHR-WVFRSLFRPDGARFAQALRRAV  243

Query  235  DVPVRWLHGTGDPVITPDLLDGYAERASD-FEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            + PV  LHG  DP + PD   G     S  +  +L+ GVGH++ E+ P+ V D +  +L 
Sbjct  244  NCPVLHLHGGADPFLLPDTAQGSGRFVSGPYAWQLLPGVGHFLPEEAPDQVSDVLLRWLD  303

Query  294  AGT  296
            A T
Sbjct  304  APT  306


>gi|288918359|ref|ZP_06412712.1| alpha/beta hydrolase fold protein [Frankia sp. EUN1f]
 gi|288350254|gb|EFC84478.1| alpha/beta hydrolase fold protein [Frankia sp. EUN1f]
Length=326

 Score =  130 bits (326),  Expect = 3e-28, Method: Compositional matrix adjust.
 Identities = 102/294 (35%), Positives = 150/294 (52%), Gaps = 21/294 (7%)

Query  13   RHVDVA-EGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGA  71
            RH DV+  G R+HVA+AG  +GP V+L+HGFPQ WW WR  +  L A G RV+  DLRG 
Sbjct  18   RHRDVSTNGTRLHVAEAG--EGPLVLLLHGFPQFWWTWRSQLRDLPAAGYRVVAADLRGY  75

Query  72   GWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGV  131
            G S  P   Y    +ADD+A ++  LG     +V HDWGG + ++  +R P  V G   +
Sbjct  76   GASDKPPRGYDAFTLADDVAGLVRALGERDAVIVGHDWGGLLGWVTAVRRPRVVRGLAVI  135

Query  132  NTVAPW-VKRDLGM------LRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGG  184
            +   P  V+R +        L + +   +Q+P    V   R++++       LL GW G 
Sbjct  136  SMPHPLRVRRRIVADVRGQGLASRYLAAFQLPW---VPERRLVAEGAAYVAELLRGWGGP  192

Query  185  GFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYND---ARVDVPVRWL  241
            G+  P+ + R Y   MR PG A +   ++R +  R  LR     + +     V VP   L
Sbjct  193  GYPTPEAEAR-YRGAMRIPGVAHSSLEYHR-WVVRSQLRPDGARFVELLRTPVRVPTLQL  250

Query  242  HGTGDPVITPDLLDGYAER--ASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            HG+ D    P    G +ER  A+ +   L DG+GH+  E+ P+ V   + A+LA
Sbjct  251  HGSLDRCFLPSTAAG-SERHVAASYTWRLYDGLGHFPHEEDPDTVTRDLVAWLA  303


>gi|325282394|ref|YP_004254935.1| Soluble epoxide hydrolase [Deinococcus proteolyticus MRP]
 gi|324314203|gb|ADY25318.1| Soluble epoxide hydrolase [Deinococcus proteolyticus MRP]
Length=280

 Score =  128 bits (322),  Expect = 1e-27, Method: Compositional matrix adjust.
 Identities = 96/284 (34%), Positives = 134/284 (48%), Gaps = 19/284 (6%)

Query  13   RHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAG  72
            RHV+   G+R+H  +AGP  GP V+L+HGFP++   W+  IGPLA  G RV+ PDLRG  
Sbjct  13   RHVN---GIRLHCLEAGPESGPPVLLLHGFPEDSRAWKKQIGPLARAGFRVVAPDLRGYH  69

Query  73   WSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFG  130
             S  P     Y    + DD+ A++  LG  +  +V HDWGG +A+ + +R PE V     
Sbjct  70   LSDRPAGVQAYRIDTLLDDVVALIHSLGYTRAHVVGHDWGGIIAWALAIRSPEVVDRLAV  129

Query  131  VNTVAPWV-KRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVP  189
            +N   P   +R+L       R WY     LP + P  +    GRY   L G  G      
Sbjct  130  LNAPHPAAFRRELRRAEQKRRSWYVAFFQLPWL-PEQLLPLLGRY--ALHGRPGS---FS  183

Query  190  DDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVI  249
              D+  Y     +PG A A   +YR      ++R+  G    ARV  P   L G  D  +
Sbjct  184  AADLTGYQAAWSQPGAASAMIHYYRA-----LVRF--GNVEGARVQAPTLLLWGMQDVAL  236

Query  250  TPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
             P+L +G  E   D  V       HW++   P  V + +  FLA
Sbjct  237  VPELSEGLEEWVPDLRVVRFPDATHWLMRDEPVRVSNLLTEFLA  280


>gi|296268202|ref|YP_003650834.1| alpha/beta hydrolase fold protein [Thermobispora bispora DSM 
43833]
 gi|296090989|gb|ADG86941.1| alpha/beta hydrolase fold protein [Thermobispora bispora DSM 
43833]
Length=301

 Score =  126 bits (317),  Expect = 4e-27, Method: Compositional matrix adjust.
 Identities = 95/286 (34%), Positives = 136/286 (48%), Gaps = 17/286 (5%)

Query  7    LEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCP  66
            +EG  H     A G R HV +AG   GP V+L+HGFPQ WW WR  +  LA  G R +  
Sbjct  10   IEGPWHHRTVHAGGTRFHVVEAG--TGPLVLLLHGFPQFWWTWRHQLVALAEAGYRAVAV  67

Query  67   DLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVT  126
            DLRG G S  P   Y    +A D A ++  LG A   +V HDWGG +A+ M +  P+ V 
Sbjct  68   DLRGYGASDKPPRGYDLPTLAVDAAGLIRALGEAGAVVVGHDWGGLIAWTMSVMDPKVVR  127

Query  127  GFFGVNTVAPWVKR-----DLGMLRNMWRFWYQIPMSLPVIGP-RVISDPKGRYFRLLTG  180
                V+   P   R      LG L+ +    + +   LP++   R+ +D      RLL  
Sbjct  128  RLVVVSAPHPLRLRAALWTTLGQLKAV---RHALAFQLPILPERRLTADGGALVARLLKS  184

Query  181  WVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLR---WLRGEYNDARVDVP  237
            W G G+  P D   +Y   +  P  A     +YR F  R  +R   +   +   AR++ P
Sbjct  185  WSGPGWP-PADVADVYRKALLIPSAANCALEYYRWF-ARSQVRPDGFHYAKQMRARIEAP  242

Query  238  VRWLHGTGDPVITPDLLDGYAER-ASDFEVELVDGVGHWIVEQRPE  282
               +HG  DP + P    G +   A+ +   L++G GH+  E+RPE
Sbjct  243  TLQVHGALDPCLLPRTAMGSSRYVAAPYRWRLIEGAGHFPHEERPE  288


>gi|226356217|ref|YP_002785957.1| hydrolase [Deinococcus deserti VCD115]
 gi|226318207|gb|ACO46203.1| putative hydrolase, alpha/beta fold family; putative epoxide 
hydrolase [Deinococcus deserti VCD115]
Length=282

 Score =  126 bits (316),  Expect = 4e-27, Method: Compositional matrix adjust.
 Identities = 88/282 (32%), Positives = 134/282 (48%), Gaps = 9/282 (3%)

Query  14   HVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGW  73
            H     GVR+H  +AGPA GP V+L+HGFP+ W  W   IGPLA  G RV+ PD+RG   
Sbjct  5    HEIQVNGVRLHYVEAGPAQGPLVVLLHGFPEYWRAWEHQIGPLARAGFRVVAPDMRGYNL  64

Query  74   SSAPRS--RYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGV  131
            S  P+    Y    + +D+A ++  LGV++  +V HDWGG VA+ + +R P+ V     +
Sbjct  65   SEKPQDLHAYRLETLQEDVAKLIQALGVSRAHMVGHDWGGIVAWQLAIRQPDVVDRLVIL  124

Query  132  NTVAPWVK-RDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPD  190
            N   P    R +     + R WY     LPV+ P +  +  GR+   L G     F    
Sbjct  125  NAPHPGAALRAMNDPEQLKRSWYVYLFQLPVL-PELFLERFGRW--ALRGTRRDAF--TP  179

Query  191  DDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVIT  250
             D+ LY    R+PG A+    +YR  +       L    ++ +V  P   + G  D  +T
Sbjct  180  QDMELYRAAWRQPGAAKGMINYYRALRRYGTRHGLERRPDNEQVGRPTLIIWGERDVALT  239

Query  251  PDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            P++ +       D  +  +    HW++   P  V + +  FL
Sbjct  240  PEMAEA-GPWVPDLRLVRLPRASHWVMRDEPVKVNNLLIDFL  280


>gi|56693357|ref|NP_001008642.1| epoxide hydrolase 2 [Danio rerio]
 gi|56269293|gb|AAH86714.1| Epoxide hydrolase 2, cytoplasmic [Danio rerio]
 gi|182890020|gb|AAI65172.1| Ephx2 protein [Danio rerio]
Length=557

 Score =  125 bits (313),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 92/306 (31%), Positives = 142/306 (47%), Gaps = 37/306 (12%)

Query  8    EGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPD  67
            E V H +V++  GV+IH  + G  DGP V+L HGFP++W+ WR  I  LA  G RVL PD
Sbjct  231  EKVSHGYVNIKPGVKIHYVEMG--DGPPVLLCHGFPESWFSWRYQIPALADAGFRVLAPD  288

Query  68   LRGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKV  125
            ++G G S+AP     Y++ ++  DL   LD + +A+V LV HDWGG + + M   HPE+V
Sbjct  289  MKGYGGSTAPPDIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHPERV  348

Query  126  TGFFGVNTVAPWVKRDLGMLRNMWR---FWYQIPMSLPVIGPRVISDPKGRYFRLL--TG  180
                 +NT    V  +   +  +     F YQI    P +    +     R F+L+  + 
Sbjct  349  RAVASLNTPLFPVDPNTNPMEKLMAIPIFDYQIYFQKPGVAEAELEKNLKRTFKLMFISS  408

Query  181  WVGGGFR----------------VPDDDVR---LYLDCMR--EPGHAEAGSR----WYRT  215
               GGF                  PDD  R   L +  ++     ++++G R    WYR 
Sbjct  409  SDTGGFPKLSPAGVCQRGGLFVGSPDDPPRSSMLSVSALQFYTEQYSKSGFRGPLNWYRN  468

Query  216  FQTREMLRWLRGEYNDARVDVPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHW  275
            ++     RW+      A++ +P   +    DPV+ P    G      +     ++  GHW
Sbjct  469  YERN--WRWMVSRPR-AKILMPALMVTAGKDPVLLPAFATGMENLIPNLSRGHIEECGHW  525

Query  276  IVEQRP  281
               +RP
Sbjct  526  TQMERP  531


>gi|115374710|ref|ZP_01461987.1| alpha/beta hydrolase [Stigmatella aurantiaca DW4/3-1]
 gi|310822697|ref|YP_003955055.1| alpha/beta hydrolase [Stigmatella aurantiaca DW4/3-1]
 gi|115368281|gb|EAU67239.1| alpha/beta hydrolase [Stigmatella aurantiaca DW4/3-1]
 gi|309395769|gb|ADO73228.1| Alpha/beta hydrolase [Stigmatella aurantiaca DW4/3-1]
Length=314

 Score =  124 bits (312),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 92/299 (31%), Positives = 148/299 (50%), Gaps = 40/299 (13%)

Query  9    GVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDL  68
            G E RH DV  GVR+     G   G  V+L+HG+ Q    W+ L+ PL A  + V+ PDL
Sbjct  40   GFEERHADV-NGVRLRYLIGG--QGSPVVLLHGYTQTSHMWQPLM-PLLAQRHTVIVPDL  95

Query  69   RGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGF  128
            RGAG SS P S Y K  +A D+ A+   LG+ +V +V HD G  VA+    + P+     
Sbjct  96   RGAGGSSKPESGYDKKTLAADIHALTSSLGLERVSIVGHDIGLMVAYAYAAQFPQATERV  155

Query  129  FGVNTVAPWVK--RDLGMLRNMWRFWY--QIPMSLPVIGPRVI---------SDPKGRYF  175
              ++   P +   +D+ +LR++W F +  ++P++L     R+          +DPK    
Sbjct  156  VLMDAFLPGIGNWKDVWLLRDLWHFHFTGEVPLALVKGRERIYFEHFWNDFAADPKR---  212

Query  176  RLLTGWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQ--TREMLRWLRGEYNDAR  233
                        VP+ D RLY     +PG   AG  +++ F+   R+       + +  R
Sbjct  213  -----------SVPEADRRLYAKAYAQPGGMRAGFEYFKAFEQDARDF-----AQLSATR  256

Query  234  VDVPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFL  292
            + +PV  L  TG+      L++     AS+ + ++V GVGHW++E+ P+ V+  +  FL
Sbjct  257  LSMPVLVL--TGEKAGGTVLIEQAKAVASEVQGQVVPGVGHWLMEEAPQTVIPAITGFL  313


>gi|115435726|ref|NP_001042621.1| Os01g0255000 [Oryza sativa Japonica Group]
 gi|5922625|dbj|BAA84626.1| putative epoxide hydrolase [Oryza sativa Japonica Group]
 gi|6016858|dbj|BAA85201.1| putative epoxide hydrolase [Oryza sativa Japonica Group]
 gi|113532152|dbj|BAF04535.1| Os01g0255000 [Oryza sativa Japonica Group]
 gi|215717145|dbj|BAG95508.1| unnamed protein product [Oryza sativa Japonica Group]
 gi|215766458|dbj|BAG98766.1| unnamed protein product [Oryza sativa Japonica Group]
Length=322

 Score =  124 bits (312),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 98/325 (31%), Positives = 152/325 (47%), Gaps = 51/325 (15%)

Query  10   VEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLR  69
            V HR V+VA GVR+HVA+AGP DGPAV+LVHGFP+ W+ WR  +  LAA G R + PDLR
Sbjct  6    VRHRTVEVASGVRLHVAEAGPEDGPAVLLVHGFPELWYSWRHQMRALAARGFRAVAPDLR  65

Query  70   GAGWSSAP--RSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTG  127
            G G S AP  R  YT   +  DL A++  +G  +V + AHDWG  VA+ + L  P+ VT 
Sbjct  66   GYGDSDAPPGRDSYTVLHLVGDLVALIADVGQPRVFVAAHDWGAAVAWQLCLLRPDLVTA  125

Query  128  FFGVN--------TVAP-----------------------WVKRDLGMLRNMWRFWYQIP  156
            F  ++        T +P                         +   G ++ + + +Y + 
Sbjct  126  FVALSVEYHPRNPTRSPVQTLRAVCGDGHYICFFQKPGVAEAEFGRGDIKCLLKKFYGMR  185

Query  157  MSLPVIGPRVISDPKGRYFRLLTGWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTF  216
             + P+I P     P    F  +         + ++D+  Y +   + G    G  +YR  
Sbjct  186  KAAPLIIP-----PGKTLFDSIDSDGTCPAWLSEEDISYYAEKFEKTGFT-GGLNYYRCI  239

Query  217  QTREMLRW-LRGEYNDARVDVPVRWLHGTGDPVIT-PDLLD-----GYAERASDFE-VEL  268
                 L W L   +    + VP +++ G  D     P + D     G      + E V +
Sbjct  240  D----LNWELTAPWTGVPIKVPTKFIVGDQDLTYNIPGVKDYIHKGGLKACVPNLEDVVI  295

Query  269  VDGVGHWIVEQRPELVLDRVRAFLA  293
            ++GV H+I +++P+ V D +  F +
Sbjct  296  MEGVAHFINQEKPDEVSDHICGFFS  320


>gi|167644459|ref|YP_001682122.1| alpha/beta hydrolase fold protein [Caulobacter sp. K31]
 gi|167346889|gb|ABZ69624.1| alpha/beta hydrolase fold [Caulobacter sp. K31]
Length=283

 Score =  124 bits (311),  Expect = 2e-26, Method: Compositional matrix adjust.
 Identities = 95/300 (32%), Positives = 141/300 (47%), Gaps = 33/300 (11%)

Query  6    ALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLC  65
             LEG EHR V V + +R+H    G  +GP ++L+HGFPQ WWEWR ++ P  A  + V+ 
Sbjct  2    TLEGFEHRMVTVGD-LRMHAVIGG--EGPPLVLIHGFPQTWWEWRRMM-PQLARRHTVVA  57

Query  66   PDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKV  125
             DLRGAG S  P+  Y K  +A+D+  V+  LG     +  HD GG  A  + L H + V
Sbjct  58   IDLRGAGHSDKPQGGYDKASLANDVHGVMLALGFDTYAVCGHDIGGMTALALALTHRQAV  117

Query  126  TGFFGVNTVAP----WVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLLTGW  181
            T    ++   P    WV+      + +W F + +   LP    R+IS   GR +  +  +
Sbjct  118  TRLIVLDVSQPGWSRWVENS--HQQKVWHFAFHMKRDLP---ERLIS---GREYDYVASF  169

Query  182  VGGGFRVPD------DDVRLYLDCMREPGHAEAGSRWYRTF--QTREMLRWLRGEYNDAR  233
            +    R  D       D+  +   + +PG+   G  WYR F       L W R       
Sbjct  170  IHD--RAFDMGAHLASDIEAFARSLAQPGNLRGGLEWYRAFPLDHENALVWKR-----EP  222

Query  234  VDVPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELVLDRVRAFLA  293
            + +PV  L   G+      ++    E A+D     V   GHW+ E+RP  V +R+  FLA
Sbjct  223  LSIPVLAL--GGEYSYGSQIVAMLQEFATDVTGGSVAACGHWMPEERPTEVTERMLGFLA  280


>gi|56962533|ref|YP_174259.1| hypothetical protein ABC0759 [Bacillus clausii KSM-K16]
 gi|56908771|dbj|BAD63298.1| conserved hypothetical protein [Bacillus clausii KSM-K16]
Length=296

 Score =  124 bits (310),  Expect = 3e-26, Method: Compositional matrix adjust.
 Identities = 83/286 (30%), Positives = 129/286 (46%), Gaps = 16/286 (5%)

Query  7    LEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCP  66
            +E  +H H+    G   H+  AG  DG  V+L+HGFP+ W+ +R  I  LA  G RV+ P
Sbjct  1    MEKYKH-HIVETGGHTFHIVSAGQEDGELVLLLHGFPEFWYGFRHQINALARAGYRVIVP  59

Query  67   DLRGAGWSSAPR--SRYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEK  124
            D RG   S  P+    YT   + DD  A +   G  +  L+ HDWGG VA+ +    PE 
Sbjct  60   DQRGYNQSDKPKDIKAYTLDVLRDDCVAFIKAFGRKQAYLIGHDWGGAVAWHLAASKPEV  119

Query  125  VTGFFGVNTVAP------WVKRDLGMLRNMWRFWYQIPMSLPVIGPRVISDPKGRYFRLL  178
            V     +N   P        K  L + R+ +  ++Q+P +      ++++     Y    
Sbjct  120  VKKLVAINIPHPAEMRVALKKHPLQLFRSAYMLFFQVPHA----PEKLLAARDFAYLEAG  175

Query  179  TGWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREMLRWLRGEYNDARVDVPV  238
                         ++R Y    R+PG  +    WYR  + + + R  + E  D  V VP 
Sbjct  176  MTKTANERAFTKAELRHYKLAWRQPGALKGMLNWYRAIRFQGVDR--KTEI-DLPVSVPT  232

Query  239  RWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRPELV  284
            R + G  D  ++  L     +R S+ +  LVDG  HW+  + PE+V
Sbjct  233  RIIWGANDQFLSKALAQASLKRCSNGDAVLVDGATHWLHHEHPEIV  278


>gi|197105739|ref|YP_002131116.1| epoxide hydrolase [Phenylobacterium zucineum HLK1]
 gi|196479159|gb|ACG78687.1| epoxide hydrolase [Phenylobacterium zucineum HLK1]
Length=319

 Score =  122 bits (305),  Expect = 9e-26, Method: Compositional matrix adjust.
 Identities = 98/300 (33%), Positives = 136/300 (46%), Gaps = 44/300 (14%)

Query  19   EGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCPDLRGAGWSSAPR  78
             GV I   +AGP  G  V+L HGFP+  + WR  I  LAA G  V+ PD RG G SS P 
Sbjct  10   NGVEIGYYEAGPRQGVPVVLCHGFPELAFSWRHQIKALAAAGRWVIAPDQRGYGLSSKPD  69

Query  79   S--RYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTVAP  136
            +   Y    +  DL  +LD LGV K     HDWGG V + M L HPE+V G  G+NT  P
Sbjct  70   AVPDYDMAHLTGDLVGLLDHLGVEKAIFCGHDWGGIVVWQMPLMHPERVAGVIGLNT--P  127

Query  137  WVKR----DLGMLR-----NMWRFWYQIP------------------MSLPVIGPRVISD  169
            ++ R     + + R     +M+  W+Q P                  M  P       + 
Sbjct  128  FLPRAPADPIAIFRHRFGPDMYIVWFQTPDEPEAVLGEDVAKTMRFFMRRPSALRTAAAQ  187

Query  170  PKG----RYFRLLTGW---VGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQTREML  222
            P+G     +  LL  W    GG   +  D++ ++++   E G       WYR F TR   
Sbjct  188  PEGGSSFAFRDLLRAWDGADGGDQLLSPDELAVFVETF-EAGGFFGPVSWYRNF-TR---  242

Query  223  RWLRGEYNDARVD-VPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWIVEQRP  281
             W R E    RVD +P   +    D V+TP++ +       D E  +V G GHW  +++P
Sbjct  243  NWERAEGLPGRVDGLPCLMITAELDAVLTPEMAEPMKGLVGDLETHMVKGSGHWTQQEKP  302


>gi|225431774|ref|XP_002270883.1| PREDICTED: hypothetical protein [Vitis vinifera]
 gi|296083336|emb|CBI22972.3| unnamed protein product [Vitis vinifera]
Length=317

 Score =  120 bits (302),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 95/330 (29%), Positives = 153/330 (47%), Gaps = 60/330 (18%)

Query  7    LEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQNWWEWRDLIGPLAADGNRVLCP  66
            +EGVEHR V  A G+ IHVA+ G  +GP ++ +HGFP++W+ WR  I  LA  G R + P
Sbjct  1    MEGVEHRTVK-ANGINIHVAEKG--EGPIILFIHGFPESWYSWRHQIHALALLGYRAVAP  57

Query  67   DLRGAGWSSAPRS--RYTKTEMADDLAAVLDGLGVAKVKLVAHDWGGPVAFIMMLRHPEK  124
            DLRG G S AP     YT   +  DL  VLD +G  KV +V HDWG  +A+ + L  P++
Sbjct  58   DLRGYGDSDAPSDVGSYTCLHVVGDLIGVLDAMGADKVFVVGHDWGAIIAWYLCLFRPDR  117

Query  125  VTGFFGVNTVAPWVKRDLGMLRNMWRFWY-------------QIPMSLPVIG--------  163
            V     + +VA + +  +     ++R  Y             QI + +  +G        
Sbjct  118  VKALVNM-SVAYFPRNPMHKPLEIYRHLYGDDFYVCRFQEPGQIEIEIAEVGTATALKSI  176

Query  164  -----PRVISDPKGRYFRLLTG-------WVGGGFRVPDDDVRLYLDCMREPGHAEAGSR  211
                 P     PKG+ F+ ++G       W      +P+++V  Y+    E G    G  
Sbjct  177  FANRDPSPPCLPKGKAFQDVSGAPIVLPPW------LPEEEVNFYVTKFEETGFT-GGIN  229

Query  212  WYRTFQTREMLRW-LRGEYNDARVDVPVRWLHGTGDPVITPDLLDGYAERASDF------  264
            +YR F       W L   +  +++ VP +++ G  D          Y   + +F      
Sbjct  230  YYRNFDR----NWELTAPWTGSQIKVPTKFMVGDMDLTYHFAGAKEYI-HSGEFKKNVPL  284

Query  265  --EVELVDGVGHWIVEQRPELVLDRVRAFL  292
              EV +++GVGH++ E++ + +   +  F 
Sbjct  285  LEEVVVMEGVGHFLHEEKADEINKHIHDFF  314



Lambda     K      H
   0.324    0.142    0.475 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 505145727648




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40