BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0139 Length=340 Score E Sequences producing significant alignments: (Bits) Value gi|15607281|ref|NP_214653.1| oxidoreductase [Mycobacterium tuber... 684 0.0 gi|326905897|gb|EGE52830.1| oxidoreductase [Mycobacterium tuberc... 684 0.0 gi|31791317|ref|NP_853810.1| putative oxidoreductase [Mycobacter... 682 0.0 gi|340625174|ref|YP_004743626.1| putative oxidoreductase [Mycoba... 677 0.0 gi|240168142|ref|ZP_04746801.1| oxidoreductase [Mycobacterium ka... 551 8e-155 gi|183980380|ref|YP_001848671.1| oxidoreductase [Mycobacterium m... 545 4e-153 gi|118619828|ref|YP_908160.1| oxidoreductase [Mycobacterium ulce... 542 4e-152 gi|342859429|ref|ZP_08716083.1| hypothetical protein MCOL_11133 ... 536 2e-150 gi|41409654|ref|NP_962490.1| hypothetical protein MAP3556 [Mycob... 536 2e-150 gi|118463099|ref|YP_884274.1| 3-beta hydroxysteroid dehydrogenas... 535 5e-150 gi|254777499|ref|ZP_05219015.1| 3-beta hydroxysteroid dehydrogen... 533 2e-149 gi|296167329|ref|ZP_06849731.1| NAD-dependent epimerase/dehydrat... 532 3e-149 gi|333988728|ref|YP_004521342.1| oxidoreductase [Mycobacterium s... 523 2e-146 gi|254822368|ref|ZP_05227369.1| 3-beta hydroxysteroid dehydrogen... 502 3e-140 gi|126438031|ref|YP_001073722.1| NAD-dependent epimerase/dehydra... 460 2e-127 gi|118469109|ref|YP_890687.1| nucleoside-diphosphate-sugar epime... 457 1e-126 gi|108802052|ref|YP_642249.1| NAD-dependent epimerase/dehydratas... 444 7e-123 gi|145221700|ref|YP_001132378.1| NAD-dependent epimerase/dehydra... 435 4e-120 gi|120406647|ref|YP_956476.1| NAD-dependent epimerase/dehydratas... 429 3e-118 gi|315446562|ref|YP_004079441.1| nucleoside-diphosphate-sugar ep... 422 3e-116 gi|126436752|ref|YP_001072443.1| NAD-dependent epimerase/dehydra... 352 5e-95 gi|120405225|ref|YP_955054.1| NAD-dependent epimerase/dehydratas... 339 4e-91 gi|118465224|ref|YP_881070.1| dihydroflavonol-4-reductase [Mycob... 339 5e-91 gi|118468005|ref|YP_890775.1| dihydrokaempferol 4-reductase [Myc... 337 1e-90 gi|333992017|ref|YP_004524631.1| oxidoreductase [Mycobacterium s... 337 2e-90 gi|209516960|ref|ZP_03265809.1| NAD-dependent epimerase/dehydrat... 331 1e-88 gi|240170409|ref|ZP_04749068.1| NAD-dependent epimerase/dehydrat... 326 3e-87 gi|343927842|ref|ZP_08767310.1| putative NAD-dependent epimerase... 324 1e-86 gi|254820601|ref|ZP_05225602.1| dihydroflavonol-4-reductase fami... 319 4e-85 gi|145222962|ref|YP_001133640.1| NAD-dependent epimerase/dehydra... 316 3e-84 gi|158313352|ref|YP_001505860.1| NAD-dependent epimerase/dehydra... 313 2e-83 gi|108797020|ref|YP_637217.1| NAD-dependent epimerase/dehydratas... 313 2e-83 gi|288921893|ref|ZP_06416106.1| NAD-dependent epimerase/dehydrat... 306 3e-81 gi|262203701|ref|YP_003274909.1| NAD-dependent epimerase/dehydra... 305 6e-81 gi|119866105|ref|YP_936057.1| NAD-dependent epimerase/dehydratas... 302 5e-80 gi|126432642|ref|YP_001068333.1| NAD-dependent epimerase/dehydra... 300 2e-79 gi|312200196|ref|YP_004020257.1| NAD-dependent epimerase/dehydra... 295 9e-78 gi|108798757|ref|YP_638954.1| NAD-dependent epimerase/dehydratas... 287 2e-75 gi|126434359|ref|YP_001070050.1| NAD-dependent epimerase/dehydra... 285 6e-75 gi|333992008|ref|YP_004524622.1| oxidoreductase [Mycobacterium s... 277 2e-72 gi|118469516|ref|YP_886599.1| dihydrokaempferol 4-reductase [Myc... 273 2e-71 gi|315442058|ref|YP_004074937.1| nucleoside-diphosphate-sugar ep... 235 6e-60 gi|120401363|ref|YP_951192.1| NAD-dependent epimerase/dehydratas... 221 2e-55 gi|145220971|ref|YP_001131649.1| NAD-dependent epimerase/dehydra... 201 1e-49 gi|88812921|ref|ZP_01128165.1| Dihydrokaempferol 4-reductase [Ni... 183 4e-44 gi|83310463|ref|YP_420727.1| nucleoside-diphosphate-sugar epimer... 179 8e-43 gi|226944176|ref|YP_002799249.1| dTDP-4-dehydrorhamnose reductas... 175 7e-42 gi|116620384|ref|YP_822540.1| NAD-dependent epimerase/dehydratas... 175 1e-41 gi|194292675|ref|YP_002008582.1| NAD-dependent epimerase/dehydra... 174 3e-41 gi|162147410|ref|YP_001601871.1| dihydroflavonol-4-reductase [Gl... 170 3e-40 >gi|15607281|ref|NP_214653.1| oxidoreductase [Mycobacterium tuberculosis H37Rv] gi|15839520|ref|NP_334557.1| dihydroflavonol 4-reductase-related protein [Mycobacterium tuberculosis CDC1551] gi|121636051|ref|YP_976274.1| putative oxidoreductase [Mycobacterium bovis BCG str. Pasteur 1173P2] 74 more sequence titles Length=340 Score = 684 bits (1766), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/340 (100%), Positives = 340/340 (100%), Gaps = 0/340 (0%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD Sbjct 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY Sbjct 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 Query 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD Sbjct 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 Query 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP Sbjct 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV Sbjct 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 Query 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS Sbjct 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 >gi|326905897|gb|EGE52830.1| oxidoreductase [Mycobacterium tuberculosis W-148] gi|339293204|gb|AEJ45315.1| oxidoreductase [Mycobacterium tuberculosis CCDC5079] Length=340 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/340 (99%), Positives = 340/340 (100%), Gaps = 0/340 (0%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD Sbjct 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY Sbjct 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 Query 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD Sbjct 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 Query 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP Sbjct 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 LQEVVR+AADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV Sbjct 241 LQEVVRVAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 Query 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS Sbjct 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 >gi|31791317|ref|NP_853810.1| putative oxidoreductase [Mycobacterium bovis AF2122/97] gi|31616902|emb|CAD93008.1| PUTATIVE OXIDOREDUCTASE [Mycobacterium bovis AF2122/97] Length=340 Score = 682 bits (1760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/340 (99%), Positives = 339/340 (99%), Gaps = 0/340 (0%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD Sbjct 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY Sbjct 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 Query 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD Sbjct 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 Query 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERG NGERYLISERMMP Sbjct 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGHNGERYLISERMMP 240 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV Sbjct 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 Query 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS Sbjct 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 >gi|340625174|ref|YP_004743626.1| putative oxidoreductase [Mycobacterium canettii CIPT 140010059] gi|340003364|emb|CCC42483.1| putative oxidoreductase [Mycobacterium canettii CIPT 140010059] Length=340 Score = 677 bits (1748), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/340 (99%), Positives = 338/340 (99%), Gaps = 0/340 (0%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD Sbjct 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY Sbjct 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 Query 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD Sbjct 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 Query 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP Sbjct 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 L +VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTG+DTELSLASVRMMRSEADV Sbjct 241 LHQVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGQDTELSLASVRMMRSEADV 300 Query 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAAS 340 DHGKAVRELGWQPRPVEESIREAARFWAAMRT GKDPAAS Sbjct 301 DHGKAVRELGWQPRPVEESIREAARFWAAMRTAGKDPAAS 340 >gi|240168142|ref|ZP_04746801.1| oxidoreductase [Mycobacterium kansasii ATCC 12478] Length=344 Score = 551 bits (1419), Expect = 8e-155, Method: Compositional matrix adjust. Identities = 278/338 (83%), Positives = 298/338 (89%), Gaps = 10/338 (2%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVFDTA 62 PKLVIGANGFLGSHV RQLV + GE VRAMVRP ANTRSIDDL LTRFHGDVFDTA Sbjct 5 PKLVIGANGFLGSHVARQLV-----EAGEQVRAMVRPKANTRSIDDLELTRFHGDVFDTA 59 Query 63 TVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD----ASLRRFVFTS 118 V EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNV GLRNVLDVA + A L RFVFTS Sbjct 60 VVREAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVEGLRNVLDVAVESPIAADLHRFVFTS 119 Query 119 SYATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGG 178 +YATVGRR GHVATE D VD +V+PYV+SRVAAE+LV++Y +AGLPAVA+CVSTTYG Sbjct 120 TYATVGRRHGHVATEADVVDVHRVSPYVQSRVAAENLVMRYVSEAGLPAVALCVSTTYGS 179 Query 179 GDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERM 238 GDWGRTPHGAFIAGAVFG+LPF M GI LEAVGVDDAA A+ILAAERGRNGERYL+SE+M Sbjct 180 GDWGRTPHGAFIAGAVFGKLPFLMTGIHLEAVGVDDAATAMILAAERGRNGERYLVSEKM 239 Query 239 MPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEA 298 + L EVVRIAADEAGVPPPR SISVPVLYALGALGSLRARLTGKD ELSL SVRMMR+EA Sbjct 240 IALTEVVRIAADEAGVPPPRRSISVPVLYALGALGSLRARLTGKDAELSLQSVRMMRAEA 299 Query 299 DVDHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKD 336 ++DHGKAVRELGWQPRPVE+SIREAARFWAAMRT D Sbjct 300 ELDHGKAVRELGWQPRPVEDSIREAARFWAAMRTARPD 337 >gi|183980380|ref|YP_001848671.1| oxidoreductase [Mycobacterium marinum M] gi|183173706|gb|ACC38816.1| oxidoreductase [Mycobacterium marinum M] Length=340 Score = 545 bits (1404), Expect = 4e-153, Method: Compositional matrix adjust. Identities = 266/328 (82%), Positives = 290/328 (89%), Gaps = 4/328 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTR L+ D A +VR MVRP ANTRSIDDLP+TRFHGD+FDTA Sbjct 5 PKLVIGANGFLGSHVTRMLIEDGA----QVRVMVRPTANTRSIDDLPVTRFHGDIFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATV 123 V EAM GCDDVYYCVVD RAWLRDP+PLF TNV GLRNVLDVA +A LRRFVFTSSYATV Sbjct 61 VREAMQGCDDVYYCVVDARAWLRDPAPLFHTNVEGLRNVLDVAKNAGLRRFVFTSSYATV 120 Query 124 GRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 RR GHVATEEDR+ +R+V+ YV+SRV AEDLV+ Y GLPAVAMCVSTTYG GDWGR Sbjct 121 DRRHGHVATEEDRIGSRRVSSYVQSRVQAEDLVMDYVAQHGLPAVAMCVSTTYGSGDWGR 180 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 TPHGAFIAGAVFG+LPF M GI+LE VGVDDAARA+ILAAERGR+G+RYLISERM+ L+E Sbjct 181 TPHGAFIAGAVFGKLPFLMNGIKLEVVGVDDAARAMILAAERGRSGQRYLISERMIALKE 240 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 VVRIAADEAGV PP+ +ISVP LYALGALGSLRARLTGKD ELSL SVRMMR+EA+VDH Sbjct 241 VVRIAADEAGVAPPQRTISVPTLYALGALGSLRARLTGKDAELSLESVRMMRAEAEVDHA 300 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KAVRELGWQPRPVEESIREAARFWA+MR Sbjct 301 KAVRELGWQPRPVEESIREAARFWASMR 328 >gi|118619828|ref|YP_908160.1| oxidoreductase [Mycobacterium ulcerans Agy99] gi|118571938|gb|ABL06689.1| oxidoreductase [Mycobacterium ulcerans Agy99] Length=340 Score = 542 bits (1396), Expect = 4e-152, Method: Compositional matrix adjust. Identities = 265/328 (81%), Positives = 289/328 (89%), Gaps = 4/328 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTR L+ D A +VR MVRP ANTRSIDDLP+TRFHGD+FDTA Sbjct 5 PKLVIGANGFLGSHVTRMLIEDGA----QVRVMVRPTANTRSIDDLPVTRFHGDIFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATV 123 V EAM GCDDVYYCVVD RAWLRDP+PLF TNV GLRNVLDVA +A LRRFVFTSSYATV Sbjct 61 VREAMQGCDDVYYCVVDARAWLRDPAPLFHTNVEGLRNVLDVAKNAGLRRFVFTSSYATV 120 Query 124 GRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 RR GHVATEEDR+ +R+V+ YV+SRV AEDLV+ Y GLPAVAMCVSTTYG GDWGR Sbjct 121 DRRHGHVATEEDRIGSRRVSSYVQSRVQAEDLVMDYVAQHGLPAVAMCVSTTYGSGDWGR 180 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 TPHGAFI GAVFG+LPF M GI+LE VGVDDAARA+ILAAERGR+G+RYLISERM+ L+E Sbjct 181 TPHGAFIVGAVFGKLPFLMNGIKLEVVGVDDAARAMILAAERGRSGQRYLISERMVALKE 240 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 VVRIAADEAGV PP+ +ISVP LYALGALGSLRARLTGKD ELSL SVRMMR+EA+VDH Sbjct 241 VVRIAADEAGVAPPQRTISVPTLYALGALGSLRARLTGKDAELSLESVRMMRAEAEVDHA 300 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KAVRELGWQPRPVEESIREAARFWA+MR Sbjct 301 KAVRELGWQPRPVEESIREAARFWASMR 328 >gi|342859429|ref|ZP_08716083.1| hypothetical protein MCOL_11133 [Mycobacterium colombiense CECT 3035] gi|342133670|gb|EGT86873.1| hypothetical protein MCOL_11133 [Mycobacterium colombiense CECT 3035] Length=339 Score = 536 bits (1380), Expect = 2e-150, Method: Compositional matrix adjust. Identities = 272/329 (83%), Positives = 290/329 (89%), Gaps = 5/329 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTRQL A A +VRAMVRP ANTR+IDDL LTRFHGDVFDTA Sbjct 5 PKLVIGANGFLGSHVTRQLAAAGA----DVRAMVRPNANTRAIDDLALTRFHGDVFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVAT-DASLRRFVFTSSYAT 122 + EAM G DDVYYCVVDTRAWLRD +PLFRTNV GLRNVLDVA LRRF+FTS+YAT Sbjct 61 LREAMDGVDDVYYCVVDTRAWLRDTAPLFRTNVEGLRNVLDVAVAQPDLRRFIFTSTYAT 120 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRGHVATEED V TR V+ YV+SRV AE+LV++Y +AGLPAVAMCVSTTYG GDWG Sbjct 121 VGRRRGHVATEEDVVGTRGVSDYVKSRVQAENLVMRYVAEAGLPAVAMCVSTTYGSGDWG 180 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 RTPHGAFIAGAVFG+LPFTM GI LE VGV DAARA+ILAAE GR GERYLISERM+ L+ Sbjct 181 RTPHGAFIAGAVFGKLPFTMEGIELEVVGVTDAARAMILAAEHGRTGERYLISERMIALK 240 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 EVVRIAADEAGVPPPR SISVPVLYALGALGSLRARL+GKD ELSLASVRMMR+EA VDH Sbjct 241 EVVRIAADEAGVPPPRRSISVPVLYALGALGSLRARLSGKDAELSLASVRMMRAEAPVDH 300 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMR 331 KAVRELGWQPRPVEESIREAARFWAAMR Sbjct 301 SKAVRELGWQPRPVEESIREAARFWAAMR 329 >gi|41409654|ref|NP_962490.1| hypothetical protein MAP3556 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398486|gb|AAS06106.1| hypothetical protein MAP_3556 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459907|gb|EGO38819.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium avium subsp. paratuberculosis S397] Length=339 Score = 536 bits (1380), Expect = 2e-150, Method: Compositional matrix adjust. Identities = 268/330 (82%), Positives = 292/330 (89%), Gaps = 5/330 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTRQLVAD A +VRAMVR ANTR IDDL LTRFHGDVFDTA Sbjct 5 PKLVIGANGFLGSHVTRQLVADGA----QVRAMVRAGANTRGIDDLSLTRFHGDVFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVA-TDASLRRFVFTSSYAT 122 ++EAM G DDVYYCVVDTRAWLRD SPLFRTNV GLRNVLDVA T LR+F+FTS+YAT Sbjct 61 LSEAMDGVDDVYYCVVDTRAWLRDTSPLFRTNVEGLRNVLDVAVTQPELRKFIFTSTYAT 120 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRGHVATE+D + TR ++ YV+SRV AE+LV++Y +AGLPAVAMCVSTTYG GDWG Sbjct 121 VGRRRGHVATEDDVIGTRGLSDYVKSRVQAENLVMRYVAEAGLPAVAMCVSTTYGSGDWG 180 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 RTPHGAFIAGAVFG+LPFTM GI+LE VGV DAA+A++LAA+RGR GERYLISERM+ L+ Sbjct 181 RTPHGAFIAGAVFGKLPFTMEGIQLEVVGVTDAAKAMVLAADRGRVGERYLISERMIALK 240 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 EVVRIAADEAGVPPPR SISVP LYALGALG LRARLTGKD ELSLASVRMMR+EA VDH Sbjct 241 EVVRIAADEAGVPPPRRSISVPTLYALGALGDLRARLTGKDAELSLASVRMMRAEAPVDH 300 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMRT 332 KAVRELGWQPRPVEESIREAARFWAAMR Sbjct 301 SKAVRELGWQPRPVEESIREAARFWAAMRN 330 >gi|118463099|ref|YP_884274.1| 3-beta hydroxysteroid dehydrogenase/isomerase [Mycobacterium avium 104] gi|118164386|gb|ABK65283.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium avium 104] Length=339 Score = 535 bits (1377), Expect = 5e-150, Method: Compositional matrix adjust. Identities = 267/330 (81%), Positives = 292/330 (89%), Gaps = 5/330 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTRQLVAD A +VRAMVR ANTR IDDL LTRFHGDVFDTA Sbjct 5 PKLVIGANGFLGSHVTRQLVADGA----QVRAMVRAGANTRGIDDLSLTRFHGDVFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVA-TDASLRRFVFTSSYAT 122 ++EAM G DDVYYCVVDTRAW+RD SPLFRTNV GLRNVLDVA T LR+F+FTS+YAT Sbjct 61 LSEAMDGVDDVYYCVVDTRAWVRDTSPLFRTNVEGLRNVLDVAVTQPELRKFIFTSTYAT 120 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRGHVATE+D + TR ++ YV+SRV AE+LV++Y +AGLPAVAMCVSTTYG GDWG Sbjct 121 VGRRRGHVATEDDVIGTRGLSDYVKSRVQAENLVMRYVAEAGLPAVAMCVSTTYGSGDWG 180 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 RTPHGAFIAGAVFG+LPFTM GI+LE VGV DAA+A++LAA+RGR GERYLISERM+ L+ Sbjct 181 RTPHGAFIAGAVFGKLPFTMEGIQLEVVGVTDAAKAMVLAADRGRVGERYLISERMIALK 240 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 EVVRIAADEAGVPPPR SISVP LYALGALG LRARLTGKD ELSLASVRMMR+EA VDH Sbjct 241 EVVRIAADEAGVPPPRRSISVPTLYALGALGDLRARLTGKDAELSLASVRMMRAEAPVDH 300 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMRT 332 KAVRELGWQPRPVEESIREAARFWAAMR Sbjct 301 SKAVRELGWQPRPVEESIREAARFWAAMRN 330 >gi|254777499|ref|ZP_05219015.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium avium subsp. avium ATCC 25291] Length=339 Score = 533 bits (1372), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 266/330 (81%), Positives = 291/330 (89%), Gaps = 5/330 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTRQLVAD A +VRAMVR ANTR IDDL LTRFHGDVFDTA Sbjct 5 PKLVIGANGFLGSHVTRQLVADGA----QVRAMVRACANTRGIDDLSLTRFHGDVFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVA-TDASLRRFVFTSSYAT 122 ++EAM G DDVYYCVVDTRAW+RD SPLFRTNV GL NVLDVA T LR+F+FTS+YAT Sbjct 61 LSEAMDGVDDVYYCVVDTRAWVRDTSPLFRTNVEGLHNVLDVAVTQPELRKFIFTSTYAT 120 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRGHVATE+D + TR ++ YV+SRV AE+LV++Y +AGLPAVAMCVSTTYG GDWG Sbjct 121 VGRRRGHVATEDDVIGTRGLSDYVKSRVQAENLVMRYVAEAGLPAVAMCVSTTYGSGDWG 180 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 RTPHGAFIAGAVFG+LPFTM GI+LE VGV DAA+A++LAA+RGR GERYLISERM+ L+ Sbjct 181 RTPHGAFIAGAVFGKLPFTMEGIQLEVVGVTDAAKAMVLAADRGRVGERYLISERMIALK 240 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 EVVRIAADEAGVPPPR SISVP LYALGALG LRARLTGKD ELSLASVRMMR+EA VDH Sbjct 241 EVVRIAADEAGVPPPRRSISVPTLYALGALGDLRARLTGKDAELSLASVRMMRAEAPVDH 300 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMRT 332 KAVRELGWQPRPVEESIREAARFWAAMR Sbjct 301 SKAVRELGWQPRPVEESIREAARFWAAMRN 330 >gi|296167329|ref|ZP_06849731.1| NAD-dependent epimerase/dehydratase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897273|gb|EFG76877.1| NAD-dependent epimerase/dehydratase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=345 Score = 532 bits (1370), Expect = 3e-149, Method: Compositional matrix adjust. Identities = 270/337 (81%), Positives = 294/337 (88%), Gaps = 5/337 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTRQLVAD P VRAMVRP ANTRSIDDL LTRFHGDVFD T Sbjct 9 PKLVIGANGFLGSHVTRQLVADRFP----VRAMVRPNANTRSIDDLELTRFHGDVFDDVT 64 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDA-SLRRFVFTSSYAT 122 + EAM G DDVYYCVVDTRAWLRDP+PLFRTNV GLRNVLDVA + LRRFVFTS+YAT Sbjct 65 LREAMDGVDDVYYCVVDTRAWLRDPAPLFRTNVEGLRNVLDVAVNQPDLRRFVFTSTYAT 124 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRGHVATE+D + R TPYV+SRV AEDLV++Y +AGLPAVAMCVSTTYG GDWG Sbjct 125 VGRRRGHVATEDDVISPRGQTPYVQSRVQAEDLVMRYVAEAGLPAVAMCVSTTYGSGDWG 184 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 TPHGAFIAGAVFG+LPF M GI+LE VGVDDAARA+ILAAERGR GERYL+SERM+ L Sbjct 185 GTPHGAFIAGAVFGKLPFGMNGIQLEVVGVDDAARAMILAAERGRIGERYLVSERMIALN 244 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 +V+RIAADEAGVPPP+ SIS+P+LYAL ALGSL+ARLTGKD+ELSLASVRMMRSEADVD Sbjct 245 DVIRIAADEAGVPPPQRSISLPMLYALSALGSLKARLTGKDSELSLASVRMMRSEADVDS 304 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMRTVGKDPAA 339 KA RELGW+PRPVEESIREAARFWAAMRT K+ A Sbjct 305 SKAKRELGWRPRPVEESIREAARFWAAMRTPRKNTPA 341 >gi|333988728|ref|YP_004521342.1| oxidoreductase [Mycobacterium sp. JDM601] gi|333484696|gb|AEF34088.1| oxidoreductase [Mycobacterium sp. JDM601] Length=341 Score = 523 bits (1347), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 265/337 (79%), Positives = 290/337 (87%), Gaps = 10/337 (2%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVFDTA 62 PKLVIGANGFLGSHVTRQLV GE VR MVRP+ANT IDDL +TR+HGDVFDTA Sbjct 5 PKLVIGANGFLGSHVTRQLV-----DAGEDVRVMVRPSANTIGIDDLDVTRYHGDVFDTA 59 Query 63 TVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD----ASLRRFVFTS 118 T+ EAM GCDD+YYCVVDTRAWLRDP+PLFRTNV GLRNVLDVA + A LRRFVFTS Sbjct 60 TLREAMTGCDDIYYCVVDTRAWLRDPAPLFRTNVEGLRNVLDVAIEEPVAAGLRRFVFTS 119 Query 119 SYATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGG 178 SY TVGRRRGHVATE D++D R++TPYVRSRV AEDLVL+YA DAGLPAVAMCVS+TYG Sbjct 120 SYVTVGRRRGHVATETDQIDRRRLTPYVRSRVQAEDLVLRYAADAGLPAVAMCVSSTYGD 179 Query 179 GDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERM 238 GDWGRTPHGAFIAGAV+G+LPF M GIRLEAVGVDDAARALILAAE GRNGERYLISERM Sbjct 180 GDWGRTPHGAFIAGAVYGKLPFVMDGIRLEAVGVDDAARALILAAEHGRNGERYLISERM 239 Query 239 MPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEA 298 + E++ IAADEAGVPPP SISVP+LYALGALG+L+ARL KD ELS SVRMMR+E+ Sbjct 240 ITNGEIIAIAADEAGVPPPARSISVPMLYALGALGALKARLGRKDAELSWKSVRMMRAES 299 Query 299 DVDHGKAVRELGWQPRPVEESIREAARFWAAMRTVGK 335 +VDH KAVRELGWQPRPVEESIREAARFW +R K Sbjct 300 EVDHSKAVRELGWQPRPVEESIREAARFWMKLRDARK 336 >gi|254822368|ref|ZP_05227369.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Mycobacterium intracellulare ATCC 13950] Length=339 Score = 502 bits (1293), Expect = 3e-140, Method: Compositional matrix adjust. Identities = 267/330 (81%), Positives = 285/330 (87%), Gaps = 5/330 (1%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 PKLVIGANGFLGSHVTRQLVA + EVRAMVR ANTRSIDDL LTRFHGDVFDTA Sbjct 5 PKLVIGANGFLGSHVTRQLVA----KGHEVRAMVRENANTRSIDDLELTRFHGDVFDTAV 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVAT-DASLRRFVFTSSYAT 122 + EAM G DDVYYCVVDTRAWLRD SPLFRTNV GLRNVLDVA LRRFVFTS+YAT Sbjct 61 LREAMDGVDDVYYCVVDTRAWLRDTSPLFRTNVEGLRNVLDVAVAQPDLRRFVFTSTYAT 120 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRG VATE+D V TR ++ YV+SRV AE+LV++ ++GLPAVAMCVSTTYG GDWG Sbjct 121 VGRRRGRVATEDDIVATRGLSDYVQSRVQAENLVMRCVAESGLPAVAMCVSTTYGSGDWG 180 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 RTPHGAFIAGAVFG+LPFTM GI+LE VGV DAA A++LAAERGR GERYLISERM+ L Sbjct 181 RTPHGAFIAGAVFGKLPFTMDGIQLEVVGVTDAAEAMLLAAERGRIGERYLISERMIALT 240 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 EVVRIAADEAGVPPPR SI VPVLY LGALGSLRARLTGKD ELSLASVRMMR+EA VDH Sbjct 241 EVVRIAADEAGVPPPRRSIPVPVLYTLGALGSLRARLTGKDAELSLASVRMMRAEAPVDH 300 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMRT 332 KAVRELGWQPRPVEESIRE ARFWAAMR Sbjct 301 SKAVRELGWQPRPVEESIREPARFWAAMRN 330 >gi|126438031|ref|YP_001073722.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] gi|126237831|gb|ABO01232.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] Length=336 Score = 460 bits (1183), Expect = 2e-127, Method: Compositional matrix adjust. Identities = 236/331 (72%), Positives = 267/331 (81%), Gaps = 4/331 (1%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LVIGANGFLGSHVTR LV EVRAMVRP A T IDDL +TRF GD++D AT+ Sbjct 5 LVIGANGFLGSHVTRLLV----DGGHEVRAMVRPNAKTVGIDDLDVTRFVGDIWDDATLR 60 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 EAM GCDDVYYCVVD R WLRDP+PLFRTNV G RNVLDVA D LRRFVFTSSY TVGR Sbjct 61 EAMTGCDDVYYCVVDARGWLRDPAPLFRTNVEGTRNVLDVARDMPLRRFVFTSSYVTVGR 120 Query 126 RRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRTP 185 RRG +TE+D D R+VTPYVRSR+ E+LVL+YA + GLPAVAMCVSTTYG GDWGRTP Sbjct 121 RRGRRSTEDDVADVRRVTPYVRSRIEGEELVLRYARERGLPAVAMCVSTTYGSGDWGRTP 180 Query 186 HGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQEVV 245 HGA IAGA FG+LPF M GI LEAVG+DDAARALILAAE+GR GERYLISE+M+ EV Sbjct 181 HGAIIAGAAFGKLPFVMSGIELEAVGIDDAARALILAAEKGRVGERYLISEKMISNAEVA 240 Query 246 RIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHGKA 305 RIAA+ AGV PP SI +PV YAL LGS+++RL G D LSL S+R+MR+EA++DH KA Sbjct 241 RIAAEAAGVAPPAKSIPLPVSYALATLGSVKSRLRGTDERLSLESLRLMRAEAELDHSKA 300 Query 306 VRELGWQPRPVEESIREAARFWAAMRTVGKD 336 VRELGWQP PVEESIREAARFW ++R V ++ Sbjct 301 VRELGWQPEPVEESIREAARFWVSLRNVKRE 331 >gi|118469109|ref|YP_890687.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium smegmatis str. MC2 155] gi|118170396|gb|ABK71292.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium smegmatis str. MC2 155] Length=340 Score = 457 bits (1177), Expect = 1e-126, Method: Compositional matrix adjust. Identities = 231/329 (71%), Positives = 263/329 (80%), Gaps = 3/329 (0%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 LVIGANGFLGSHV RQLVAD E+RAMVRP ANT IDDL +TRF GD+FDT + Sbjct 4 SLVIGANGFLGSHVLRQLVADNT-DGSEIRAMVRPGANTVGIDDLDVTRFTGDIFDTEVL 62 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD--ASLRRFVFTSSYAT 122 AM GCD VYYCVVDTR WLR P+PLFRTNV G R+VLDVA + LR+FV+TSSY T Sbjct 63 RAAMTGCDVVYYCVVDTRGWLRHPAPLFRTNVEGTRHVLDVALEPGIGLRKFVYTSSYVT 122 Query 123 VGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 VGRRRG VATE+D +D R VTPYVRSRV AE+LVL+YA + GLPAVAMCVSTTYG GDWG Sbjct 123 VGRRRGCVATEDDVIDLRGVTPYVRSRVQAEELVLRYATERGLPAVAMCVSTTYGSGDWG 182 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 RTPHGA IAGA FG+LPF M GI LEAVGVDDAARALILAAE GR GERYLISE+++ Sbjct 183 RTPHGAVIAGAAFGKLPFVMSGIDLEAVGVDDAARALILAAESGRPGERYLISEKLISNA 242 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 EV RIAA+ AGV PPR SI +PV Y L A+G+++ +L G D LSL S+R+MR+E ++DH Sbjct 243 EVARIAAEAAGVAPPRRSIPLPVSYLLAAIGTVKGKLRGTDERLSLRSLRLMRAECELDH 302 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMR 331 KAVRELGWQPRPVEESI EAA+FW +R Sbjct 303 SKAVRELGWQPRPVEESIAEAAKFWVGLR 331 >gi|108802052|ref|YP_642249.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS] gi|119871204|ref|YP_941156.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS] gi|108772471|gb|ABG11193.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS] gi|119697293|gb|ABL94366.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS] Length=336 Score = 444 bits (1143), Expect = 7e-123, Method: Compositional matrix adjust. Identities = 234/331 (71%), Positives = 263/331 (80%), Gaps = 4/331 (1%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LVIGANGFLGSHVTRQLV EVRAMVRP A T IDDL +TRF GD++D AT+ Sbjct 5 LVIGANGFLGSHVTRQLV----DGGHEVRAMVRPNAKTVGIDDLDVTRFVGDIWDDATLR 60 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 EAM GCDDVYYCVVD R WLRDP+PLFRTNV G RNVLDVA D LRRFVFTSSY TVGR Sbjct 61 EAMTGCDDVYYCVVDARGWLRDPAPLFRTNVEGTRNVLDVARDMPLRRFVFTSSYVTVGR 120 Query 126 RRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRTP 185 RRG +TE+D D R+VTPYVRSR+ E+LVL A + GLPAVAMCVSTTYG GDWGRTP Sbjct 121 RRGRRSTEDDVADVRRVTPYVRSRIEGEELVLSNARERGLPAVAMCVSTTYGSGDWGRTP 180 Query 186 HGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQEVV 245 HGA IA A FG+LPF M GI LEAVG+DDAARALILAAE+GR GERYLISE+M+ EV Sbjct 181 HGAIIAAAAFGKLPFVMSGIELEAVGIDDAARALILAAEKGRAGERYLISEKMISNAEVA 240 Query 246 RIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHGKA 305 RIAA+ AGV PP SI +PV Y L LGS+++RL G D LSL S+R+MR+EA++DH KA Sbjct 241 RIAAEAAGVAPPAKSIPLPVSYVLATLGSVKSRLRGTDERLSLESLRLMRAEAELDHSKA 300 Query 306 VRELGWQPRPVEESIREAARFWAAMRTVGKD 336 VRELGWQP PVEESIREAARFW +R V ++ Sbjct 301 VRELGWQPGPVEESIREAARFWVNLRNVRRE 331 >gi|145221700|ref|YP_001132378.1| NAD-dependent epimerase/dehydratase [Mycobacterium gilvum PYR-GCK] gi|145214186|gb|ABP43590.1| NAD-dependent epimerase/dehydratase [Mycobacterium gilvum PYR-GCK] Length=343 Score = 435 bits (1119), Expect = 4e-120, Method: Compositional matrix adjust. Identities = 220/339 (65%), Positives = 264/339 (78%), Gaps = 12/339 (3%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M+AP LVIGANG+LGSHVTR+LVA +VR MVR ANT IDDL +TR+ GD+++ Sbjct 1 MSAPVLVIGANGYLGSHVTRKLVA----AGNDVRVMVRDGANTVGIDDLAVTRYVGDIWN 56 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD----ASLRRFVF 116 T + EAM GC+ VYYCVVDTR WLRDP+PLFRTNV G RNVLDVA + A+LR+FVF Sbjct 57 TDVLREAMTGCEVVYYCVVDTRGWLRDPAPLFRTNVEGTRNVLDVAVEPGIAATLRKFVF 116 Query 117 TSSYATVGRRRGHVATEEDRV----DTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCV 172 TSS TVGR RG VATE D + D + +TPYVRSRV AE+LV++YA + GLPAVAMCV Sbjct 117 TSSCVTVGRTRGRVATEADVISDPADLKSLTPYVRSRVQAENLVMEYARERGLPAVAMCV 176 Query 173 STTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERY 232 STTYG GDWGRTPHGA IAGA FG+LPF M GI LEAVG+DDAA+A++LAA +GR GERY Sbjct 177 STTYGAGDWGRTPHGAIIAGAAFGKLPFVMGGIELEAVGIDDAAQAMLLAARKGRAGERY 236 Query 233 LISERMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVR 292 LISE+M+ +VVRIAA+ AGVP P I + + YA+ ALGS ++RL G D +SL S+R Sbjct 237 LISEKMISNADVVRIAAEAAGVPAPTKKIPLVLSYAMAALGSAKSRLKGTDERMSLGSLR 296 Query 293 MMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMR 331 +MR+EA VD KA RELGWQPRPVEESIREAA+FW ++ Sbjct 297 LMRAEAPVDCSKARRELGWQPRPVEESIREAAKFWVGLK 335 >gi|120406647|ref|YP_956476.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii PYR-1] gi|119959465|gb|ABM16470.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii PYR-1] Length=339 Score = 429 bits (1104), Expect = 3e-118, Method: Compositional matrix adjust. Identities = 225/329 (69%), Positives = 261/329 (80%), Gaps = 8/329 (2%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LVIGANG+LGSHVTR+LVAD +VR MVR ANT IDDL +TRF GD++D + Sbjct 4 LVIGANGYLGSHVTRRLVADGQ----DVRVMVREGANTIGIDDLTVTRFVGDIWDDDVLR 59 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD----ASLRRFVFTSSYA 121 EAM GCD VYYCVVDTR WLRDP+PLFRTNV G RNVL++A + A LR+FVFTSSY Sbjct 60 EAMTGCDVVYYCVVDTRGWLRDPAPLFRTNVEGTRNVLNIAVEPAVAAGLRKFVFTSSYV 119 Query 122 TVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDW 181 TVGRRRG VATE D + R +TPYVRSRV AE+LVL+YA GLPAVAMCVSTTYG GDW Sbjct 120 TVGRRRGRVATEADVIADRGLTPYVRSRVQAENLVLEYARTRGLPAVAMCVSTTYGAGDW 179 Query 182 GRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPL 241 GRTPHGA IAGA FG+LPF + GI LEAVGV+DAA AL+LAAE+GR GERYLISE+M+ Sbjct 180 GRTPHGAIIAGAAFGKLPFVLGGIELEAVGVEDAAHALLLAAEKGRVGERYLISEKMISN 239 Query 242 QEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVD 301 +VVRIAA+ AGVP P ++ +P+ YA+ ALGSL+ RL G D LSL S+R+MR+EA VD Sbjct 240 ADVVRIAAEAAGVPAPSRTMPLPLSYAMAALGSLKGRLKGTDERLSLDSLRLMRAEAPVD 299 Query 302 HGKAVRELGWQPRPVEESIREAARFWAAM 330 GKA RELGWQPRPVEESIREAA+FW + Sbjct 300 CGKAKRELGWQPRPVEESIREAAKFWVGL 328 >gi|315446562|ref|YP_004079441.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] gi|315264865|gb|ADU01607.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] Length=343 Score = 422 bits (1086), Expect = 3e-116, Method: Compositional matrix adjust. Identities = 219/339 (65%), Positives = 266/339 (79%), Gaps = 12/339 (3%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M+AP LVIGANG+LGSHVTR+LVA +VR MVR ANT IDDL +TR+ GD+++ Sbjct 1 MSAPVLVIGANGYLGSHVTRKLVA----AGNDVRVMVRDGANTVGIDDLAVTRYVGDIWN 56 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD----ASLRRFVF 116 + + EAM GC+ VYYCVVDTR WLRDP+PLFRTNV G RNVLDVA + A+LR+FVF Sbjct 57 SDVLREAMTGCEVVYYCVVDTRGWLRDPAPLFRTNVEGTRNVLDVAVEPGIAATLRKFVF 116 Query 117 TSSYATVGRRRGHVATEEDRV----DTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCV 172 TSSY TVGR RG VATE D + D + +TPYVRSRV AE+LV++YA + GLPAVAMCV Sbjct 117 TSSYVTVGRTRGRVATEADVISDPADLKSLTPYVRSRVQAENLVMEYARERGLPAVAMCV 176 Query 173 STTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERY 232 STTYG GDWGRTPHGA IAG+ FG+LPF M GI LEAVG+DDAA+A++LAA++GR GERY Sbjct 177 STTYGAGDWGRTPHGAIIAGSAFGKLPFVMGGIELEAVGIDDAAQAMLLAAQKGRAGERY 236 Query 233 LISERMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVR 292 LISE+M+ +VVRIAA+ AGVP P I + + YA+ ALGS ++RL G D +SL S+R Sbjct 237 LISEKMISNADVVRIAAEAAGVPAPTKKIPLVLSYAMAALGSAKSRLKGTDERMSLGSLR 296 Query 293 MMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMR 331 +MR+EA VD KA RELGWQPRPVEESIREAA+FW ++ Sbjct 297 LMRAEAPVDCSKARRELGWQPRPVEESIREAAKFWVGLK 335 >gi|126436752|ref|YP_001072443.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] gi|126236552|gb|ABN99952.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] Length=336 Score = 352 bits (903), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 184/335 (55%), Positives = 238/335 (72%), Gaps = 7/335 (2%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 KLVIGA+GFLGSHV RQLV ++GE VR ++R ++T++ DDL + R +GD+FD Sbjct 6 KLVIGASGFLGSHVVRQLV-----ERGERVRVLIRATSSTKAFDDLDVERCYGDIFDDQA 60 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATV 123 V EAM GCDDV+YCVVD RAWLRDP+PLFRTNV GLR++LD+A +A L RFVFTSS T+ Sbjct 61 VREAMTGCDDVFYCVVDARAWLRDPAPLFRTNVDGLRHILDIAAEADLHRFVFTSSIGTI 120 Query 124 GRRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 ATE+ + K Y+RSRV AE+LVL YA D GLPAVAMCVS TYG GDW Sbjct 121 ALNADGAATEDMPFNWIDKGGAYIRSRVEAENLVLGYARDRGLPAVAMCVSNTYGPGDWQ 180 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 TPHG+ +A A G++PF ++G+ +E VG++DAARAL+LAAERGR GERY+IS+R + + Sbjct 181 PTPHGSLVAAAAAGKMPFYVKGMAMEVVGIEDAARALVLAAERGRPGERYIISDRFISAR 240 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 E+ AA AGV PRW + + ++YALG G L A + +D LS SVR+M + +DH Sbjct 241 ELYTAAAAAAGVRGPRWGVPLKIMYALGFAGDLAAAMLRRDLLLSSMSVRLMHIMSPMDH 300 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMRTVGKDP 337 GKA RELGW+P P+ +SIR+A F+ A R + P Sbjct 301 GKAERELGWRPEPIVDSIRKAVDFYRARRADEEGP 335 >gi|120405225|ref|YP_955054.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii PYR-1] gi|119958043|gb|ABM15048.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii PYR-1] Length=337 Score = 339 bits (869), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 176/328 (54%), Positives = 226/328 (69%), Gaps = 4/328 (1%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M KLVIGA+GFLGSHVT+QL+A + +VR ++R ++TR ID LP+ +GD+FD Sbjct 1 MAGTKLVIGASGFLGSHVTKQLIA---AGEDDVRVLIRTTSSTRGIDGLPVQVHYGDIFD 57 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 T + AMAGCD VYYCVVD R WLRDP+P++RTNV GLRNVLDVA A L RFVFTSS Sbjct 58 TGALRAAMAGCDVVYYCVVDARPWLRDPAPMWRTNVDGLRNVLDVAVGAGLHRFVFTSSI 117 Query 121 ATVGRRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGG 179 T+G +A E+ + K Y+RSRV AE +VL+Y+ + GLPAVAMCV+ TYG G Sbjct 118 GTIGLAADGLADEDTAHNWLDKGGAYIRSRVEAEQMVLRYSAEKGLPAVAMCVANTYGPG 177 Query 180 DWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMM 239 D+ TPHG +A AV GRLPF + G E VG++DAARA+ILAAERGR GERY++SER M Sbjct 178 DFLPTPHGGMLAAAVAGRLPFYIDGYDAEVVGIEDAARAMILAAERGRTGERYIVSERFM 237 Query 240 PLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEAD 299 +E+ I GV PP++ + + V+ A G L ARL GKDT L+ ++R+M + Sbjct 238 STREIHEIGCAAVGVAPPKFGVPIRVMSAAGYLSEGVARLRGKDTMLTPLNIRLMHIMSP 297 Query 300 VDHGKAVRELGWQPRPVEESIREAARFW 327 +DH KAVREL W P+P E+I AA F+ Sbjct 298 MDHSKAVRELDWHPQPTSEAIVAAAHFF 325 >gi|118465224|ref|YP_881070.1| dihydroflavonol-4-reductase [Mycobacterium avium 104] gi|118166511|gb|ABK67408.1| dihydroflavonol-4-reductase family protein [Mycobacterium avium 104] Length=327 Score = 339 bits (869), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 177/328 (54%), Positives = 231/328 (71%), Gaps = 8/328 (2%) Query 3 APKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVFDT 61 A KLVIGA+GFLGSHVTRQLV ++GE VR ++R ++T ++DDL + R +GDVFD Sbjct 2 AVKLVIGASGFLGSHVTRQLV-----ERGERVRVLLRRTSSTVALDDLDIERRYGDVFDD 56 Query 62 ATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYA 121 A + +A+ GCDDVYYCVVDTRAWLRDP+PLFRTNV GLR VLD A A LRRFVFTS+ Sbjct 57 AVLRDALDGCDDVYYCVVDTRAWLRDPAPLFRTNVEGLRQVLDTAVGADLRRFVFTSTIG 116 Query 122 TVGRRRGHVATEEDRVDT--RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGG 179 T+ + ED + Y+RSRV AE+LVLQYA + GLPAVAMCVS TYG G Sbjct 117 TIALSEDGLPVSEDEPFNWADRGGGYIRSRVEAENLVLQYARERGLPAVAMCVSNTYGPG 176 Query 180 DWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMM 239 D+ TPHG+ +A A G++P ++ + +E VG++DAARALILAAE+GR GERY++SER + Sbjct 177 DFQPTPHGSLVAAAGKGKMPVYVKDMSMEVVGIEDAARALILAAEKGRVGERYIVSERYI 236 Query 240 PLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEAD 299 +E+ AA+ G PPR I + V+YALG G + A++ +D LS SVR+M + Sbjct 237 SARELYTTAAEAGGARPPRIGIPLKVMYALGLCGDVAAKVLRRDMLLSTLSVRLMHIMSP 296 Query 300 VDHGKAVRELGWQPRPVEESIREAARFW 327 +DH KA RELGW+P P+ ++IR A F+ Sbjct 297 MDHSKAERELGWRPEPIHDAIRRAVAFY 324 >gi|118468005|ref|YP_890775.1| dihydrokaempferol 4-reductase [Mycobacterium smegmatis str. MC2 155] gi|118169292|gb|ABK70188.1| dihydrokaempferol 4-reductase [Mycobacterium smegmatis str. MC2 155] Length=336 Score = 337 bits (865), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 189/340 (56%), Positives = 234/340 (69%), Gaps = 15/340 (4%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRF---HG 56 M A KLVIGA+GFLGSHVTR+LV ++GE VR ++R ++TR IDD+ + R HG Sbjct 1 MTATKLVIGASGFLGSHVTRRLV-----ERGEDVRILIRSTSSTRGIDDV-IDRVDVRHG 54 Query 57 DVFDTATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATD----ASLR 112 D+FD A+V +A GCD VYYCVVD RAWLRD +PL+RTNV GL VLDV T+ + +R Sbjct 55 DIFDAASVRDAADGCDTVYYCVVDARAWLRDATPLWRTNVDGLSGVLDVMTEPEIASGVR 114 Query 113 RFVFTSSYATVGRRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMC 171 RFVFTSS AT+G ATEE + + YVRSRV AE LVL+Y D GLPAVAMC Sbjct 115 RFVFTSSIATIGLPESGPATEEIENNWLDRGGEYVRSRVRAEQLVLRYHKDRGLPAVAMC 174 Query 172 VSTTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGER 231 VS TYG GDW TPHG +A AV G++PF + G EAVGV DAA AL+LA ERG GER Sbjct 175 VSNTYGPGDWQPTPHGGLVAAAVRGKMPFYIDGAEAEAVGVADAAEALVLAGERGTPGER 234 Query 232 YLISERMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASV 291 Y++SERMM +E+ +A D GV PPR + + V+ A L S ARL ++T LS +V Sbjct 235 YIVSERMMSAREIYEVACDAVGVEPPRRGVPIRVMAAAAGLSSAVARLRRRETRLSPLTV 294 Query 292 RMMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMR 331 R+M + +DHGKAVRELGW+P P ESI +AARF+A+ R Sbjct 295 RLMHVMSPMDHGKAVRELGWKPAPAPESIAQAARFFASRR 334 >gi|333992017|ref|YP_004524631.1| oxidoreductase [Mycobacterium sp. JDM601] gi|333487985|gb|AEF37377.1| oxidoreductase [Mycobacterium sp. JDM601] Length=336 Score = 337 bits (864), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 182/335 (55%), Positives = 226/335 (68%), Gaps = 11/335 (3%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVF 59 M KLVIG++GFLGSHVTRQLV GE VR ++R ++TR+ID L + GD+F Sbjct 1 MVKKKLVIGSSGFLGSHVTRQLV-----DAGEDVRVLIRATSSTRAIDGLDVDVRRGDIF 55 Query 60 DTATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSS 119 D V AM GCD VYYCVVD RAWL DP PL+RTNV LR+VLDVA A+L RFVFTSS Sbjct 56 DQDAVRSAMNGCDVVYYCVVDARAWLTDPEPLYRTNVEALRHVLDVAAGAALDRFVFTSS 115 Query 120 YATVGRRRGHVATE---EDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTY 176 T+GR +A E + +D+ Y+RSRV AE+LVL Y D GLPAVAMCV+ TY Sbjct 116 IGTIGRVDHGLADERTAHNWLDSGG--DYIRSRVEAENLVLGYHRDKGLPAVAMCVANTY 173 Query 177 GGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISE 236 G GDW TPHG +A AV G+LPF + G + E VGVDDAARALILA +RGR G+RY++SE Sbjct 174 GSGDWQPTPHGGLVAAAVRGKLPFYISGAQAEVVGVDDAARALILAGQRGRPGQRYIVSE 233 Query 237 RMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRS 296 R M +++ R A V PPRW + V V+ ALG L ARL +DT L+ S+R+M Sbjct 234 RFMSARDIYRTACAAVDVEPPRWGVPVAVMSALGHLAQFAARLRRRDTALTPLSIRLMHI 293 Query 297 EADVDHGKAVRELGWQPRPVEESIREAARFWAAMR 331 + + H KAVRELGW+PRP E++ EAA F+ + R Sbjct 294 MSPMSHDKAVRELGWEPRPATEALAEAAGFFRSRR 328 >gi|209516960|ref|ZP_03265809.1| NAD-dependent epimerase/dehydratase [Burkholderia sp. H160] gi|209502629|gb|EEA02636.1| NAD-dependent epimerase/dehydratase [Burkholderia sp. H160] Length=352 Score = 331 bits (848), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 176/328 (54%), Positives = 224/328 (69%), Gaps = 7/328 (2%) Query 2 NAPKLVIGANGFLGSHVTRQLVADCAPQKG-EVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 A KLVIGA+GFLGSHVTRQL Q+G VR +VRP ++TR+ID LP+ R GD+FD Sbjct 3 TAIKLVIGASGFLGSHVTRQLT-----QEGYNVRVLVRPRSDTRAIDGLPVERIFGDIFD 57 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 + A+ CD V+YC D RAWLRDP PLF TNV GLR+VLDVA A+L+RFVFTSS Sbjct 58 DQVLQLALQDCDTVFYCAADARAWLRDPKPLFDTNVDGLRHVLDVAVAANLKRFVFTSSI 117 Query 121 ATVGRRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGG 179 T+GR E ++ + Y+RSRV AE LV Y D GLPAV MCV+ TYG G Sbjct 118 CTIGRTSHSKLDEAPILNWNEEEHSYIRSRVEAERLVRSYCLDRGLPAVTMCVANTYGHG 177 Query 180 DWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMM 239 DW TP G +A A G+L F + G EAVGV+DAA ALILA ++GR GERY++S+R + Sbjct 178 DWRPTPLGRMVADAALGKLRFYIDGHEGEAVGVEDAAAALILAGQKGRIGERYIVSDRFI 237 Query 240 PLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEAD 299 +E+ AA+ GV PR +S+ +YALG LG++ +RL G+D L+ SVR+M + + Sbjct 238 STRELFEAAAEATGVRTPRIRVSLRWMYALGTLGNILSRLLGRDLMLTTNSVRLMHNTSP 297 Query 300 VDHGKAVRELGWQPRPVEESIREAARFW 327 +DHGKA RELGW PRPVEE++REAA F+ Sbjct 298 MDHGKAERELGWSPRPVEEAVREAALFF 325 >gi|240170409|ref|ZP_04749068.1| NAD-dependent epimerase/dehydratase [Mycobacterium kansasii ATCC 12478] Length=333 Score = 326 bits (835), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 185/329 (57%), Positives = 225/329 (69%), Gaps = 9/329 (2%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTR----FHGDVFD 60 KLVIGA+GFLGSHVTRQLVA A Q +VR MVR + T+ IDDL TR +GD+FD Sbjct 6 KLVIGASGFLGSHVTRQLVA--AGQ--DVRVMVRRTSVTKGIDDLLQTRKVERCYGDIFD 61 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 A + EAMAGCD VYYCVVD R WLRDP+PLFRTNV GLR+VLD A DA LR+FVFTSS Sbjct 62 DAALREAMAGCDVVYYCVVDARMWLRDPTPLFRTNVEGLRHVLDAALDAQLRKFVFTSST 121 Query 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 T+ TE+D + Y+ SRVA E+LV+QY + GLPAVAMC+STTYG GD Sbjct 122 GTLAINDQRPVTEDDPHNWNDGGAYIESRVAGENLVMQYVREKGLPAVAMCISTTYGPGD 181 Query 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 W TPHG+ IA GR PF + G E VG++DAARA++LAA+RGR GERY+IS+R + Sbjct 182 WAPTPHGSLIARVATGRFPFYL-GFSAEVVGIEDAARAMLLAADRGRVGERYIISDRYLS 240 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 +E+ IAA G+ PPR I +PV+ A L L ARL +D + RM + + Sbjct 241 TREIHEIAARAVGIRPPRIPIPMPVMRAAARLNDLAARLLRRDLLFAYVGARMAELMSPL 300 Query 301 DHGKAVRELGWQPRPVEESIREAARFWAA 329 DH KA RELGW P PVE+SIR+AARF+ A Sbjct 301 DHSKAERELGWTPEPVEDSIRKAARFFVA 329 >gi|343927842|ref|ZP_08767310.1| putative NAD-dependent epimerase/dehydratase family protein [Gordonia alkanivorans NBRC 16433] gi|343762483|dbj|GAA14236.1| putative NAD-dependent epimerase/dehydratase family protein [Gordonia alkanivorans NBRC 16433] Length=330 Score = 324 bits (830), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 182/328 (56%), Positives = 235/328 (72%), Gaps = 5/328 (1%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 KLV+G NGFLG+ + R LV + + +VR + RP ++ R++ L GD+FD +V Sbjct 2 KLVVGGNGFLGARLVRHLVGN----EDDVRVLTRPTSDLRTLSGLDFEHVTGDLFDADSV 57 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG 124 AM GCD V++C VDTRAWLRDP+PL+RTNV GLR VLDVA LRRFVFTS+ AT+G Sbjct 58 RAAMDGCDVVFHCAVDTRAWLRDPAPLYRTNVDGLRAVLDVAATQPLRRFVFTSTAATIG 117 Query 125 RRRGHVATEEDRVDTRKVTP-YVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 R +G +ATE+D + K P YV+SRVAAE+L++ Y+ D +P V MCV+ TYG GDW Sbjct 118 RVQGRLATEDDAFNWPKHAPGYVKSRVAAENLLMDYSRDGAVPGVVMCVANTYGPGDWQP 177 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 TPHG+F+AGA G+LPFT+RG R E+VG+DDAARAL LAAERG GERY+++ER + E Sbjct 178 TPHGSFVAGAALGKLPFTIRGCRAESVGIDDAARALALAAERGEVGERYIVAERSIDTGE 237 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 +V IAA AG PPR ++ P LYA GA GS RA LT K +L++ SVR+M +++DHG Sbjct 238 IVEIAARTAGREPPRLVLNRPALYAAGAAGSARAALTRKPVQLTVPSVRLMHFMSEMDHG 297 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KA R+LGW+PRPV E+I E ARFW R Sbjct 298 KAERDLGWRPRPVTEAIAEGARFWLERR 325 >gi|254820601|ref|ZP_05225602.1| dihydroflavonol-4-reductase family protein [Mycobacterium intracellulare ATCC 13950] Length=325 Score = 319 bits (817), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 173/329 (53%), Positives = 218/329 (67%), Gaps = 5/329 (1%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M KLVIGA+GFLGSHVTRQLVA +VR M+R ++T IDDL + R +GDVFD Sbjct 1 MADKKLVIGASGFLGSHVTRQLVA----AGEDVRVMLRHTSSTAGIDDLDVERCYGDVFD 56 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 A + AMAGCD VYYCVVD R LRDP+PLFRTNV GLR+VLD A A L+RFV+TS+ Sbjct 57 DAALRAAMAGCDVVYYCVVDARMCLRDPAPLFRTNVEGLRHVLDAALGADLKRFVYTSTT 116 Query 121 ATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGD 180 ++ G TEED + + Y+ +RVA EDL+L YA D GLP VAMC+STTYG GD Sbjct 117 GSLAISDGKPVTEEDPHNWDQGGAYIEARVAGEDLLLSYARDKGLPGVAMCISTTYGPGD 176 Query 181 WGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 W TPHGA +A GR PF E VG++DAARA++LAAE R+GERY++S+R M Sbjct 177 WAPTPHGALLALVAKGRFPFYF-DYSSEVVGIEDAARAMLLAAEHARDGERYIVSDRYMS 235 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 ++E+ IAA G PR I + VL A + A L G+D + A +RM + + Sbjct 236 IRELHEIAATAVGRRSPRIGIPMSVLRAGARVNDAAAWLLGRDLPFAYAGIRMAELMSPL 295 Query 301 DHGKAVRELGWQPRPVEESIREAARFWAA 329 DH KA RELGW P PVE+SIR+AA ++A+ Sbjct 296 DHSKATRELGWTPEPVEDSIRKAAVWFAS 324 >gi|145222962|ref|YP_001133640.1| NAD-dependent epimerase/dehydratase [Mycobacterium gilvum PYR-GCK] gi|315443424|ref|YP_004076303.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] gi|145215448|gb|ABP44852.1| NAD-dependent epimerase/dehydratase [Mycobacterium gilvum PYR-GCK] gi|315261727|gb|ADT98468.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] Length=338 Score = 316 bits (810), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 174/334 (53%), Positives = 226/334 (68%), Gaps = 8/334 (2%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M KLVIGA+GFLGSHVTRQLVAD +VR ++R ++TR ID LP+ +GD+FD Sbjct 1 MAGTKLVIGASGFLGSHVTRQLVAD---GDADVRVLIRRTSSTRGIDGLPVEVRYGDIFD 57 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 + AM+GCD VYYCVVD R WLRDP P++RTNV GLR VLD+A DA L RFVFTSS Sbjct 58 ADALRTAMSGCDVVYYCVVDARPWLRDPRPMWRTNVDGLRTVLDIAADAGLTRFVFTSSI 117 Query 121 ATVGRRRGHVA---TEEDRVDTRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYG 177 T+G R G A TE + +D + Y+RSRV AE++VL+ + LP VAMCV+ TYG Sbjct 118 GTIGLRAGGPADERTEHNWLD--RGGEYIRSRVVAEEMVLRDSARNRLPGVAMCVANTYG 175 Query 178 GGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISER 237 GD+ TPHGA +A AV G+LPF +RG EAVG++DAARA+ILA ERGR GERY++S+R Sbjct 176 PGDFQPTPHGAMLAAAVRGKLPFYIRGYEAEAVGIEDAARAMILAGERGRIGERYIVSDR 235 Query 238 MMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSE 297 + +E+ I G+ PPR+ + + + A LG+ AR+ DT L+ ++R+M Sbjct 236 FISTREIHEIGCAAVGMRPPRFGVPIRAMAAAAHLGAAVARVRNTDTMLTPLNIRLMHIM 295 Query 298 ADVDHGKAVRELGWQPRPVEESIREAARFWAAMR 331 +DH KAVRELGW PRP+ +SI AA F+ R Sbjct 296 TPLDHSKAVRELGWHPRPLADSIVSAAHFFTDRR 329 >gi|158313352|ref|YP_001505860.1| NAD-dependent epimerase/dehydratase [Frankia sp. EAN1pec] gi|158108757|gb|ABW10954.1| NAD-dependent epimerase/dehydratase [Frankia sp. EAN1pec] Length=349 Score = 313 bits (803), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 164/329 (50%), Positives = 219/329 (67%), Gaps = 7/329 (2%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M LV+GA+GFLGSHVTRQL A + +VR +R +++TR+ DDLP+ R +G++ D Sbjct 17 MVGTHLVMGASGFLGSHVTRQL----AERGDDVRVWIRRSSSTRAFDDLPVQRCYGELVD 72 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 A + EAM G D VYYC+VDTRAWLRDP+PLF TNV GLR+ LD A +A +RRFVF S+ Sbjct 73 DAAIREAMHGVDTVYYCIVDTRAWLRDPAPLFATNVDGLRHALDAALEAQVRRFVFCSTV 132 Query 121 ATVGRRRGHVATEEDRVDTRKVT--PYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGG 178 T+G +E T + PY+++RVAAE+LVL+Y + GLP + MCVSTTYG Sbjct 133 GTIGLSPDGRPADESVPHTWEHLGGPYIQTRVAAENLVLRYCREHGLPGIVMCVSTTYGA 192 Query 179 GDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERM 238 D G +PHG ++ A GRLPF +E VG+ DAARA +LAAE+GR GERY+ISER Sbjct 193 PDHG-SPHGRMVSDAAKGRLPFYFGNAAMEVVGISDAARAFLLAAEKGRVGERYIISERY 251 Query 239 MPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEA 298 M +E+V AAD G PPR I +PV+ A+G LG + R+ +D ++ S R+M Sbjct 252 MTWKELVTTAADAGGAKPPRVGIPLPVMKAVGRLGDVAGRVLRRDVVMNSVSTRLMHFMP 311 Query 299 DVDHGKAVRELGWQPRPVEESIREAARFW 327 +DH KA RELGW P P +++R AA+F+ Sbjct 312 PLDHSKATRELGWDPSPTPDAVRAAAKFY 340 >gi|108797020|ref|YP_637217.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS] gi|108767439|gb|ABG06161.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS] Length=335 Score = 313 bits (802), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 173/328 (53%), Positives = 219/328 (67%), Gaps = 5/328 (1%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 KLVIGA+GFLGSHVTR+LV + +VR ++R ++TR ID LP+ +GD+FD V Sbjct 4 KLVIGASGFLGSHVTRRLVE----RGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAV 59 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG 124 A+AGCD VYYCVVD RAWLRDP+PL+RTNV GL+ VLDV DA L RFVFTSS AT+G Sbjct 60 RAAVAGCDVVYYCVVDARAWLRDPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIG 119 Query 125 RRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 ATEE + + YVR+RVAAEDLVL+Y + LPAVAMCVS TYG DW Sbjct 120 IADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERALPAVAMCVSNTYGPDDWLP 179 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 TPHG +A AV G+LPF + G + E VGV DAA ALILA ERGR GERY++SER M +E Sbjct 180 TPHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTARE 239 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 + + A GV PP+ + + L A + ARL +DT + ++R+M + +DH Sbjct 240 IYQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRFTPLTIRLMHIMSPMDHS 299 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KA RELGW+P P +++ EAA F+ R Sbjct 300 KAERELGWRPAPTTDALAEAAEFFVGNR 327 >gi|288921893|ref|ZP_06416106.1| NAD-dependent epimerase/dehydratase [Frankia sp. EUN1f] gi|288346741|gb|EFC81057.1| NAD-dependent epimerase/dehydratase [Frankia sp. EUN1f] Length=335 Score = 306 bits (784), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 163/329 (50%), Positives = 213/329 (65%), Gaps = 7/329 (2%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFD 60 M +LV+GA+GFLGSHVTRQL A + +VR +R ++T + DDL + R HG++ D Sbjct 1 MADTQLVMGASGFLGSHVTRQL----AERGDDVRVWIRKTSSTVAFDDLEVERVHGELTD 56 Query 61 TATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSY 120 A + EAM G D VYYC+VD RAWLRDP+PLF TNV GLR+VLD A +A +RRFVF S+ Sbjct 57 DAALLEAMRGVDTVYYCIVDARAWLRDPAPLFATNVEGLRHVLDAAVEAKVRRFVFCSTV 116 Query 121 ATVGRRRGHVATEEDRVDTRKVT--PYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGG 178 T+GR +ED T K PY+++R AEDLVLQY + LP V M VSTTYG Sbjct 117 GTIGRSDDGGPADEDDPHTWKHLGGPYIQARADAEDLVLQYCRERDLPGVVMNVSTTYGA 176 Query 179 GDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERM 238 D +PHG +A A G++P +E VG+ DAARA +LAAE+GR GERY+ISE Sbjct 177 PDHA-SPHGQLVAEAARGKMPIYFGKASMEVVGIRDAARAFLLAAEKGRIGERYIISESY 235 Query 239 MPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEA 298 M +E+V IAA+ GV PPR I +PV+ +G LG ++ +DT ++ SVR+ Sbjct 236 MTWKELVTIAAETGGVKPPRIGIPIPVMKVIGRLGDFGQKVLRRDTVMNSVSVRLTHFMP 295 Query 299 DVDHGKAVRELGWQPRPVEESIREAARFW 327 +DH KA RELGW+P P + IREAA F+ Sbjct 296 PLDHSKATRELGWEPSPTADEIREAALFY 324 >gi|262203701|ref|YP_003274909.1| NAD-dependent epimerase/dehydratase [Gordonia bronchialis DSM 43247] gi|262087048|gb|ACY23016.1| NAD-dependent epimerase/dehydratase [Gordonia bronchialis DSM 43247] Length=334 Score = 305 bits (781), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 173/327 (53%), Positives = 215/327 (66%), Gaps = 5/327 (1%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LV+G NGFLGSH+ RQL + VR + R ++ R + L GD+FD ++ Sbjct 4 LVVGGNGFLGSHLVRQL----CDRADRVRVLTRATSDLRPLAGLSYEHVVGDIFDAPSIE 59 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 AM G D V++C VDTRAWL DP+PLFRTNV GL VLD A + FVFTS+ AT+GR Sbjct 60 SAMRGADTVFHCAVDTRAWLTDPAPLFRTNVEGLGVVLDAAATVGVESFVFTSTMATIGR 119 Query 126 RRGHVATEEDRVDTR-KVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRT 184 G V E D + T YVRSRVA E+L L+YA + +P VAMCVS TYG GDW T Sbjct 120 HPGRVVDESDEFNWHASATDYVRSRVAGEELALRYAREERVPVVAMCVSNTYGAGDWQPT 179 Query 185 PHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQEV 244 PHG+F+A A G++PF +RG+R EAV VDDAARALI AA+RGR GERY++SER + L EV Sbjct 180 PHGSFVAAAALGKMPFGIRGMRAEAVDVDDAARALIAAADRGRTGERYIVSERFIDLGEV 239 Query 245 VRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHGK 304 + AA AGV PPR + LYA GA+GSLRARLTG+ L + +VR+M + + H K Sbjct 240 ITTAAAAAGVAPPRLVLGKRSLYAAGAVGSLRARLTGRSQRLRIDTVRLMHHMSQMSHAK 299 Query 305 AVRELGWQPRPVEESIREAARFWAAMR 331 A REL W PRPV ++I E ARFW R Sbjct 300 AERELDWHPRPVTDAIAEGARFWVDRR 326 >gi|119866105|ref|YP_936057.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS] gi|119692194|gb|ABL89267.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS] Length=335 Score = 302 bits (774), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 174/328 (54%), Positives = 220/328 (68%), Gaps = 5/328 (1%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 KLVIGA+GFLGSHVTR+LV + +VR ++R ++TR ID LP+ +GD+FD V Sbjct 4 KLVIGASGFLGSHVTRRLVE----RGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAV 59 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG 124 A+AGCD VYYCVVD RAWLRDP+PL+RTNV GL+ VLDV DA L RFVFTSS AT+G Sbjct 60 RAAVAGCDVVYYCVVDARAWLRDPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIG 119 Query 125 RRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 ATEE + + YVR+RVAAEDLVL+Y + LPAVAMCVS TYG DW Sbjct 120 IADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERALPAVAMCVSNTYGPDDWLP 179 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 TPHG +A AV G+LPF + G + E VGV DAA ALILA ERGR GERY++SER M +E Sbjct 180 TPHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTARE 239 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 + + A GV PP+ + + L A + ARL +DT L+ ++R+M + +DH Sbjct 240 IYQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRLTPLTIRLMHIMSPMDHS 299 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KA RELGW+P P +++ EAA F+ R Sbjct 300 KAERELGWRPAPTTDALAEAAEFFVGNR 327 >gi|126432642|ref|YP_001068333.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] gi|126232442|gb|ABN95842.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] Length=335 Score = 300 bits (768), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 173/328 (53%), Positives = 220/328 (68%), Gaps = 5/328 (1%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 KLVIGA+GFLGSHVTR+LV + +VR ++R ++TR ID LP+ R +GD+FD V Sbjct 4 KLVIGASGFLGSHVTRRLVE----RGDDVRVLIRHTSSTRGIDGLPVERHYGDIFDDDAV 59 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG 124 A+AGCD V YCVVD RAWLRDP+PL+RTNV GL+ VLDV DA L RFVFTSS AT+G Sbjct 60 RAAVAGCDVVCYCVVDARAWLRDPAPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIG 119 Query 125 RRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 ATEE + + YVR+RVAAE+LVL+Y + LPAVAMCVS TYG DW Sbjct 120 IADSGPATEELSHNWLDRAGEYVRTRVAAENLVLRYHRERALPAVAMCVSNTYGPDDWLP 179 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 TPHG +A AV G+LPF + G + E VGV DAA ALILA ERGR GERY++SER M +E Sbjct 180 TPHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTARE 239 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 + + A GV PP+ + + L A + ARL +DT L+ ++R+M + +DH Sbjct 240 IYQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRLTPLTIRLMHIMSPMDHS 299 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KA RELGW+P P +++ EAA F+ R Sbjct 300 KAERELGWRPAPTTDALAEAAEFFVGNR 327 >gi|312200196|ref|YP_004020257.1| NAD-dependent epimerase/dehydratase [Frankia sp. EuI1c] gi|311231532|gb|ADP84387.1| NAD-dependent epimerase/dehydratase [Frankia sp. EuI1c] Length=344 Score = 295 bits (754), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 154/324 (48%), Positives = 212/324 (66%), Gaps = 6/324 (1%) Query 5 KLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 +LV+GA+GFLGSHVTRQLV + +VR +R +++TR+ DDLP+ R +G++ D + Sbjct 17 QLVMGASGFLGSHVTRQLV----ERGDDVRVWIRRSSSTRAFDDLPVQRCYGELTDDEAM 72 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG 124 EAM D V+YCVVD RAWLRDP+PLF TNV GLR+ LD A + +RRFVF S+ T+G Sbjct 73 REAMRDVDTVFYCVVDARAWLRDPAPLFATNVDGLRHALDAALEMKVRRFVFCSTVGTIG 132 Query 125 RRRGHVATEEDRVDTRKVT-PYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 +A EE + + PY+R+RVAAE+LVL+Y GLP + M VSTTYG D+G Sbjct 133 VSTDGLADEELPHNWMHLGGPYIRARVAAEELVLEYCRQRGLPGIVMNVSTTYGAPDFG- 191 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 +PHG ++ A G+LP +E VG+ DAA A +LA ++GR GERY+ISE M QE Sbjct 192 SPHGRMVSDAALGKLPIYFGNASMEVVGITDAAAAFLLAGQKGRVGERYIISESFMSWQE 251 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 +V AA+ G PPR+ I + V+ G LG L R+ +D ++ +VR+M + +DHG Sbjct 252 LVTTAAEAVGTRPPRFGIPIGVMKVFGRLGDLGGRVLRRDMVMTSVTVRLMHFMSPLDHG 311 Query 304 KAVRELGWQPRPVEESIREAARFW 327 KA REL W P P +SIR AA+++ Sbjct 312 KASRELDWHPAPTRDSIRAAAKYY 335 >gi|108798757|ref|YP_638954.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS] gi|119867875|ref|YP_937827.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS] gi|108769176|gb|ABG07898.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. MCS] gi|119693964|gb|ABL91037.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. KMS] Length=346 Score = 287 bits (734), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 160/328 (49%), Positives = 216/328 (66%), Gaps = 7/328 (2%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LV+GA+G +G+ V R LVAD +VR ++R +++TR ID L + R +GD+FDT VA Sbjct 15 LVLGASGNVGAAVVRHLVAD----GDDVRVLLRRSSSTRGIDGLDVDRRYGDIFDTEAVA 70 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 AMA D V+YCVVDTRA L DP+PLF TNV GLR VLD+A A L+RFVF S+ T+ Sbjct 71 AAMADRDVVFYCVVDTRAHLADPAPLFATNVEGLRGVLDIAARADLKRFVFLSTIGTIAV 130 Query 126 RRGHVATEEDRVD--TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 A +ED + K PY+ SR AEDLVL+ A + GLPAVAMCVS YG DW Sbjct 131 GADGAAVDEDTPFNWSGKGGPYIESRRQAEDLVLRCARERGLPAVAMCVSNPYGPPDWN- 189 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 GA +A A FG++P +RG+ E V +DDAARAL+ AAERGR GERY++SER M +E Sbjct 190 PRQGALVALAAFGKMPCYIRGVGAEVVDIDDAARALVSAAERGRVGERYIVSERYMSQRE 249 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 ++ +AA+ AG PPR+ I + +++A A+ + RL G D ++ A+ R++ + DHG Sbjct 250 MLTLAAEAAGATPPRFGIPMALVHAFAAVAGMSNRLFGTDLPINPAAARLIALTSPADHG 309 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KA R+LGW+P P ++IR AAR + R Sbjct 310 KATRDLGWRPGPTADAIRRAARSYVERR 337 >gi|126434359|ref|YP_001070050.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] gi|126234159|gb|ABN97559.1| NAD-dependent epimerase/dehydratase [Mycobacterium sp. JLS] Length=342 Score = 285 bits (730), Expect = 6e-75, Method: Compositional matrix adjust. Identities = 159/328 (49%), Positives = 216/328 (66%), Gaps = 7/328 (2%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LV+GA+G +G+ V R LVAD +VR ++R +++TR ID L + R +GD+FDT VA Sbjct 11 LVLGASGNVGAAVVRHLVAD----GDDVRVLLRRSSSTRGIDGLDVDRRYGDIFDTEAVA 66 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 AMA D V+YCVVDTRA L DP+PLF TNV GLR VLD+A A L+RFVF S+ T+ Sbjct 67 AAMADRDVVFYCVVDTRAHLADPAPLFATNVEGLRGVLDIAARADLKRFVFLSTIGTIAV 126 Query 126 RRGHVATEEDRVD--TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 A +ED + K PY+ SR AEDLVL+ A + GLPAVAMCVS YG DW Sbjct 127 GADGAAVDEDTPFNWSGKGGPYIESRRQAEDLVLRCARERGLPAVAMCVSNPYGPPDWN- 185 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 GA +A A FG++P +RG+ E V +DDAARAL+ AA+RGR GERY++SER M +E Sbjct 186 PRQGALVALAAFGKMPCYIRGVGAEVVDIDDAARALVSAADRGRVGERYIVSERYMSQRE 245 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 ++ +AA+ AG PPR+ I + +++A A+ + RL G D ++ A+ R++ + DHG Sbjct 246 MLTLAAEAAGATPPRFGIPMALVHAFAAVAGMSNRLFGTDLPINPAAARLIALTSPADHG 305 Query 304 KAVRELGWQPRPVEESIREAARFWAAMR 331 KA R+LGW+P P ++IR AAR + R Sbjct 306 KATRDLGWRPGPTADAIRRAARSYVERR 333 >gi|333992008|ref|YP_004524622.1| oxidoreductase [Mycobacterium sp. JDM601] gi|333487976|gb|AEF37368.1| oxidoreductase [Mycobacterium sp. JDM601] Length=343 Score = 277 bits (709), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 162/328 (50%), Positives = 208/328 (64%), Gaps = 15/328 (4%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LV+GA+G +G+ VTR LVA + +VR ++R +++T+ ID L + R +GD+FDT VA Sbjct 19 LVMGASGNVGACVTRHLVA----RGDDVRVLLRRSSSTKGIDGLDVQRHYGDIFDTEAVA 74 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG- 124 AMA + VYYCVVDTRA LRDP+PLFRTNV GLRNVL+VA +A L +FVF S+ T+ Sbjct 75 AAMADREVVYYCVVDTRAELRDPAPLFRTNVEGLRNVLEVAANADLDKFVFLSTIGTIAV 134 Query 125 RRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 R G EE + + Y+ SR AE LVL YA D GLPAV VS YG DW + Sbjct 135 GRNGETVDEETPFNWADQGGAYIASRREAERLVLSYAADRGLPAVVTNVSNPYGPPDW-Q 193 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 G + A G++P RG+ E VG+DDAAR LILAAERGR G+RY+ISER M +E Sbjct 194 PRQGMLVQLAALGKMPAYARGVGSEVVGIDDAARGLILAAERGRIGQRYIISERYMSQRE 253 Query 244 VVRIAADEAGVPPPRWSISVPVLY----ALGALGSLRARLTGKDTELSLASVRMMRSEAD 299 ++ IAA E G PPR+ I + VL+ +GALG+L R D + R+M + Sbjct 254 MLTIAAHEVGATPPRFGIPMAVLHIAGQVVGALGALLRR----DFAFTATGARLMALTSP 309 Query 300 VDHGKAVRELGWQPRPVEESIREAARFW 327 DH KA RELGW P P E +IR AARF+ Sbjct 310 ADHSKATRELGWHPEPTERAIRSAARFY 337 >gi|118469516|ref|YP_886599.1| dihydrokaempferol 4-reductase [Mycobacterium smegmatis str. MC2 155] gi|118170803|gb|ABK71699.1| dihydrokaempferol 4-reductase [Mycobacterium smegmatis str. MC2 155] Length=339 Score = 273 bits (699), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 160/325 (50%), Positives = 210/325 (65%), Gaps = 9/325 (2%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVFDTATV 64 LV+GA+G +G+ VTRQLV ++G+ VR ++R ++T+ ID L + R +GD+FDT V Sbjct 8 LVMGASGNVGACVTRQLV-----ERGDDVRVLLRRNSSTKGIDGLDVERHYGDIFDTGAV 62 Query 65 AEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVG 124 A A+A D V+YCVVDTRA L P+PLFRTNV GLRNVL+VA L RFVF S+ T+ Sbjct 63 AAAVADRDVVFYCVVDTRAHLAAPAPLFRTNVEGLRNVLEVADHVDLHRFVFLSTIGTIA 122 Query 125 RRRGHVATEEDRVDTRKVT--PYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWG 182 R A +ED PY+ SR AE+LVL YA + G PAV M VS YG DW Sbjct 123 VGRNGEAVDEDTPFNWAGIGGPYIESRRKAEELVLSYAAERGFPAVVMNVSNPYGPPDW- 181 Query 183 RTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 + GA +A A FG+LP +RG+ E VG+DDAARALILAAE GR GERY++SER M Q Sbjct 182 QPRQGALVAMAAFGKLPVYIRGVGAEVVGIDDAARALILAAEHGRIGERYIVSERYMSQQ 241 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 E++ +AA+ G PPR I + +YA G+L L RL D ++L + R+M + DH Sbjct 242 EMLTVAAEAVGARPPRIGIPMAAVYAFGSLAGLSNRLFRTDFPINLTAARLMWWTSPADH 301 Query 303 GKAVRELGWQPRPVEESIREAARFW 327 KA RELGW+P P ++I AA+F+ Sbjct 302 SKATRELGWKPAPTADAIARAAQFY 326 >gi|315442058|ref|YP_004074937.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] gi|315260361|gb|ADT97102.1| nucleoside-diphosphate-sugar epimerase [Mycobacterium sp. Spyr1] Length=340 Score = 235 bits (600), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 146/331 (45%), Positives = 192/331 (59%), Gaps = 7/331 (2%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LV+GA+G +G+ VTR L A A +VR ++RP ++TR ID + R GD FD AT A Sbjct 14 LVMGASGNVGACVTRHLAAGGA----DVRVLLRPTSSTRGIDGADIDRRLGDPFDPATAA 69 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 AMA D VYYC+VDTRA L+DP+PLF TNV GLR VLDVA DA+L +FVF S+ T+ Sbjct 70 AAMADRDVVYYCIVDTRAELKDPAPLFATNVEGLRKVLDVAADANLDKFVFLSTIGTIAV 129 Query 126 RRGHVATEEDRVDT--RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 +ED + Y+ SR AAE LVL YA + G+PAV + VS YG DW + Sbjct 130 GANGEQVDEDTPFNWADRAGSYIESRRAAEQLVLSYAAERGVPAVVVNVSNPYGPPDW-Q 188 Query 184 TPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQE 243 G F+ A G++PF +RG+ E VG+DDAA A++ A+ RGR GERY+ SER M +E Sbjct 189 PRQGMFVQMAALGKMPFYVRGVGSEVVGIDDAADAMLRASVRGRVGERYIASERFMTHRE 248 Query 244 VVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHG 303 +V AAD G PR I + V+Y L + +S S ++ + H Sbjct 249 LVTTAADAVGARRPRIGIPMSVVYGFAYLADAIGSVLPVQVPMSRQSAFLLAHTSPASHA 308 Query 304 KAVRELGWQPRPVEESIREAARFWAAMRTVG 334 KA RELGW P+P E I AA + + G Sbjct 309 KATRELGWTPKPTEGFIARAAEHYVQRQQAG 339 >gi|120401363|ref|YP_951192.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii PYR-1] gi|119954181|gb|ABM11186.1| NAD-dependent epimerase/dehydratase [Mycobacterium vanbaalenii PYR-1] Length=325 Score = 221 bits (562), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 135/316 (43%), Positives = 185/316 (59%), Gaps = 7/316 (2%) Query 14 LGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVAEAMAGCDD 73 +G+ V RQL A A +VR ++R +++T+ +D + + R GD FD AT A AMA D Sbjct 1 MGACVARQLAAGGA----DVRVLLRKSSSTKGVDRIDVERAVGDPFDPATAAAAMADRDV 56 Query 74 VYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGRRRGHVATE 133 VYYC+VDTRA L+DP+PLF TNV GLR VLDVA A+L+RFVF S+ T+ + Sbjct 57 VYYCIVDTRAELKDPAPLFATNVEGLRKVLDVAAAANLKRFVFLSTIGTIAVGENGETVD 116 Query 134 EDRVDT--RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRTPHGAFIA 191 ED + Y+ SR AAE LVL YA + GLPAV + VS YG D+ + G F+ Sbjct 117 EDTPFNWADRAGGYIESRRAAEQLVLSYATERGLPAVVVNVSNPYGPPDF-QPRQGMFVQ 175 Query 192 GAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQEVVRIAADE 251 A G+LPF ++G+ E VG+DDAA A++ A+ RGR GERY+ SER M +E++ AAD Sbjct 176 LAALGKLPFYVKGVGAEVVGIDDAADAMLRASLRGRVGERYIASERFMTHRELLTTAADA 235 Query 252 AGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHGKAVRELGW 311 G PR+ + + V+Y L + +S S ++ + H KA RELGW Sbjct 236 VGARRPRFGVPMAVVYGFAWLADAVGSILPVQVPMSRQSAFLLAHTSPASHAKATRELGW 295 Query 312 QPRPVEESIREAARFW 327 P+P E I AA + Sbjct 296 HPKPTENFIARAAENY 311 >gi|145220971|ref|YP_001131649.1| NAD-dependent epimerase/dehydratase [Mycobacterium gilvum PYR-GCK] gi|145213457|gb|ABP42861.1| NAD-dependent epimerase/dehydratase [Mycobacterium gilvum PYR-GCK] Length=264 Score = 201 bits (512), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 115/268 (43%), Positives = 153/268 (58%), Gaps = 13/268 (4%) Query 74 VYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGRRRGHVATE 133 VYYC+VDTRA L+DP+PLF TNV GLR VLDVA DA+L +FVF S+ T+ V + Sbjct 2 VYYCIVDTRAELKDPAPLFATNVEGLRKVLDVAADANLDKFVFLSTIGTIA-----VGAD 56 Query 134 EDRVD-------TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRTPH 186 ++VD + Y+ SR AAE LVL YA + G+PAV + VS YG DW + Sbjct 57 GEQVDEDTPFNWAERAGSYIESRRAAEQLVLSYAAERGVPAVVVNVSNPYGPPDW-QPRQ 115 Query 187 GAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQEVVR 246 G F+ A G++PF +RG+ E VG+DDAA A++ A+ RGR GERY+ SER M +E+V Sbjct 116 GMFVQMAALGKMPFYVRGVGSEVVGIDDAADAMLRASVRGRVGERYIASERFMTHRELVT 175 Query 247 IAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDHGKAV 306 AAD G PR I + V+Y L + +S S ++ + H KA Sbjct 176 TAADAVGARRPRIGIPMAVVYGFAYLADAIGSVLPVQVPMSRQSAFLLAHTSPASHAKAT 235 Query 307 RELGWQPRPVEESIREAARFWAAMRTVG 334 RELGW P+P E I AA + + G Sbjct 236 RELGWTPKPTEGFIARAAEHYVQRQQAG 263 >gi|88812921|ref|ZP_01128165.1| Dihydrokaempferol 4-reductase [Nitrococcus mobilis Nb-231] gi|88789843|gb|EAR20966.1| Dihydrokaempferol 4-reductase [Nitrococcus mobilis Nb-231] Length=330 Score = 183 bits (464), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 122/327 (38%), Positives = 180/327 (56%), Gaps = 17/327 (5%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTAT 63 P L+ GA+GF+GS V R+L A EVR +VRP ++ R+++ L + F GD+ AT Sbjct 3 PTLLTGASGFVGSAVLRRLQA----AGHEVRVLVRPTSSRRNLEGLDVEVFTGDLTQPAT 58 Query 64 VAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATV 123 +A A+ GC +++ D R W RDP L+R+NV G R +L A +A + R V+TSS AT+ Sbjct 59 LARAVRGCRVLFHAAADYRLWSRDPRALYRSNVEGTRYMLAAALEAGVERVVYTSSVATL 118 Query 124 GRRRGHVATEEDRVDTR--KVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDW 181 G R HV +E T V Y RS+ AE+ V + GLP V + ST G D Sbjct 119 GIRSDHVPADEATPATLVDMVGHYKRSKYLAEEEVRRLIRATGLPVVIVNPSTPIGPRDL 178 Query 182 GRTPHGAFIAGAVFGRLP-FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 TP G + A GR+P + G+ + V VDD A +LA E G+ GERY++ M Sbjct 179 KPTPTGRMVLDAAAGRMPAYVDTGLNI--VHVDDVAHGHLLALEHGQVGERYILGGTNMS 236 Query 241 LQEVVRIAADEAGVPPPR----WSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRS 296 L+E++ A G PPP+ +S+ +P+ YA A AR++G++ +++ VRM + Sbjct 237 LREILIQIAAIVGRPPPKLRLPYSLVLPIAYAAEAW----ARVSGREPRVNVNGVRMAKK 292 Query 297 EADVDHGKAVRELGWQPRPVEESIREA 323 KA R LG+ PRP E ++ +A Sbjct 293 HMYFSSTKAERVLGYSPRPAEAALEDA 319 >gi|83310463|ref|YP_420727.1| nucleoside-diphosphate-sugar epimerase [Magnetospirillum magneticum AMB-1] gi|82945304|dbj|BAE50168.1| Nucleoside-diphosphate-sugar epimerase [Magnetospirillum magneticum AMB-1] Length=330 Score = 179 bits (453), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 124/345 (36%), Positives = 189/345 (55%), Gaps = 23/345 (6%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVF 59 M P LV GA GF+G+ + R L+A +GE VR + RPA++ R++ +L + G + Sbjct 1 MAGPVLVTGATGFVGAAIVRALLA-----RGEAVRVLARPASDRRNVANLHVEVAEGRLE 55 Query 60 DTATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSS 119 D A++ +AMAGC + + D R W+ DP+ + + NV G R +++ A + R V+TSS Sbjct 56 DAASLRKAMAGCRVLIHTAADYRIWVPDPAAMMKANVEGTRTLMEAALAEKVERVVYTSS 115 Query 120 YATVGRRRGHVATEEDRVD-TRKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGG 178 AT+G G VA E+ D + KV PY +S+ AE++V + + GLPAV ST G Sbjct 116 VATLGHVEGGVADEDTPSDISDKVGPYKQSKFLAEEVVRRMVAEQGLPAVICSPSTPIGP 175 Query 179 GDWGRTPHGAFIAGAVFGRLP-FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISER 237 GD TP G I A GR+P + G+ + V VDD A +LA ++GR GERY++ Sbjct 176 GDVKPTPTGRMIVEAASGRMPAYVDTGLNI--VHVDDVAAGHLLALDKGRIGERYILGGE 233 Query 238 MMPLQEVV-RIAADEAGVPP----PRWSISVPVLYALGALGSLRARLTGKDTELSLASVR 292 + L +++ RIA G PP PRW LY L AR G + +++ ++ Sbjct 234 NLTLADILNRIAKITGGRPPLMKLPRWP-----LYPLALGAETWARFFGGEPFVTVDGLK 288 Query 293 MMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMRTVGKDP 337 M R KA RELG++ RP +E++ +AA W +++G+ P Sbjct 289 MSRWHMFFSSAKAERELGYRHRPADEAL-DAAVEW--FKSIGEVP 330 >gi|226944176|ref|YP_002799249.1| dTDP-4-dehydrorhamnose reductase RmlD [Azotobacter vinelandii DJ] gi|226719103|gb|ACO78274.1| dTDP-4-dehydrorhamnose reductase, RmlD [Azotobacter vinelandii DJ] Length=340 Score = 175 bits (444), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 117/329 (36%), Positives = 176/329 (54%), Gaps = 10/329 (3%) Query 6 LVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDTATVA 65 LV GA GF+GS V R+L+ D VR +VR +++ R++ DL + GD+ A++ Sbjct 19 LVTGATGFVGSAVVRRLLRD----DHHVRVLVRASSDRRNLQDLNVQVVEGDLTQAASLQ 74 Query 66 EAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYATVGR 125 A GCD +++ D R W P L+RTNV G R +L+ A A + R V+TSS AT+G Sbjct 75 HACDGCDALFHVAADYRLWAPFPEQLYRTNVEGTRVILEAAKSAGVPRIVYTSSVATLGI 134 Query 126 RRGHVATEEDRVDTRK--VTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGR 183 + +E+ T + + Y RS+ AE LV ++A + GLP V + ST G D Sbjct 135 PKDGRPGDENTAVTERDMIGHYKRSKFLAESLVREFAAE-GLPVVIVNPSTPIGPRDIKP 193 Query 184 TPHGAFIAGAVFGRLP-FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMPLQ 242 TP G + A+ GRLP + G+ + V VDD A LA + G GERY++ + + L+ Sbjct 194 TPTGRIVRDAIAGRLPAYVDTGLNI--VHVDDVAEGHWLAFQHGVVGERYILGGQNLTLR 251 Query 243 EVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADVDH 302 E++ AD AG+ PPRW + + + L + ARL+G ++ VRM R Sbjct 252 EMLAEIADIAGLAPPRWRLPHAAVMPIAHLAEVWARLSGTQPIATVEEVRMSRKYMFFSS 311 Query 303 GKAVRELGWQPRPVEESIREAARFWAAMR 331 KA RELG+ P PV ++ +A ++ R Sbjct 312 AKAERELGYTPGPVRLAMEDAVMWFRQHR 340 >gi|116620384|ref|YP_822540.1| NAD-dependent epimerase/dehydratase [Candidatus Solibacter usitatus Ellin6076] gi|116223546|gb|ABJ82255.1| NAD-dependent epimerase/dehydratase [Candidatus Solibacter usitatus Ellin6076] Length=323 Score = 175 bits (443), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 118/327 (37%), Positives = 174/327 (54%), Gaps = 14/327 (4%) Query 4 PKLVIGANGFLGSHVTRQLVADCAPQKG-EVRAMVRPAANTRSIDDLPLTRFHGDVFDTA 62 P LV GA+GFLG HV R LV ++G VRA+VRP + ID +T GD+ D A Sbjct 3 PALVTGASGFLGWHVARVLV-----ERGLHVRALVRPGSKVVGIDVECVT---GDLRDPA 54 Query 63 TVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYAT 122 ++A A+ GC V++ D R W +DP+ L+R+NV G RN+L+ A A + R V+TS+ Sbjct 55 SLALAVKGCGLVFHVAADYRLWAKDPTELYRSNVDGTRNLLEAARQAGVERTVYTSTVGC 114 Query 123 VGRRRGHVATEEDRVDTRKVT-PYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDW 181 +G R + E V + Y RS+ AE + L++A AG P V + + G D Sbjct 115 IGMPRDGIGDEAQPVKLAHMAGDYKRSKFLAEKVALEFAR-AGQPVVIVNPTAPLGDHDV 173 Query 182 GRTPHGAFIAGAVFGRLP-FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISERMMP 240 TP G + + G +P F G L V V D A A ERGR+GERY++ + Sbjct 174 KPTPTGKIVLDFLKGDMPAFIDTG--LNVVDVRDTAEGHWQACERGRSGERYILGSENLT 231 Query 241 LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSEADV 300 L ++++ A G P + + Y GA + A +TG+ + L +VRM + + V Sbjct 232 LAQILQKLAAITGRKAPTLQLPYALAYCAGACSTAWAAVTGRPPRVPLEAVRMAKKKMWV 291 Query 301 DHGKAVRELGWQPRPVEESIREAARFW 327 H KA RELG+QP P E+++R A ++ Sbjct 292 SHDKAARELGFQPGPAEKALRHAVDWF 318 >gi|194292675|ref|YP_002008582.1| NAD-dependent epimerase/dehydratase [Cupriavidus taiwanensis LMG 19424] gi|193226579|emb|CAQ72530.1| putative NAD-dependent epimerase/dehydratase [Cupriavidus taiwanensis LMG 19424] Length=335 Score = 174 bits (440), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 128/338 (38%), Positives = 176/338 (53%), Gaps = 11/338 (3%) Query 2 NAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDLPLTRFHGDVFDT 61 N LV GA GFLGS V RQ +A + VR +VRP + ++ LP+T GD+ D Sbjct 4 NDDVLVTGAAGFLGSAVARQALA----RGWRVRVLVRPQSPRTNLAGLPVTVAQGDMRDA 59 Query 62 ATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSSYA 121 VA A+ G +++ D R W RDP + RTNV G V++ A A + R V+TSS A Sbjct 60 DAVAAALQGVRYLFHVAADYRLWARDPEDIVRTNVDGTLAVMEAAQRAGVERVVYTSSVA 119 Query 122 TVGRRRGHVATEEDRVDTRK---VTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGG 178 T+ R G A ++ R + Y RS+V AE +V Q + GLPAV + ST G Sbjct 120 TL-RVAGAQAPVDETAALRPHEAIGAYKRSKVLAERVVEQRVAEHGLPAVIVNPSTPIGP 178 Query 179 GDWGRTPHGAFIAGAVFGRLP-FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISER 237 D TP G I A G++P F G+ L VDD A LA ERGR GERY++ Sbjct 179 RDVRPTPTGRIIVEAATGKIPAFVDTGLNL--AHVDDVAHGHFLALERGRTGERYILGGE 236 Query 238 MMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRSE 297 + LQ+++R A G PP + LY L ARLTGK+ L++ + M R Sbjct 237 DVMLQQMLRDIARLCGRRPPTLQLPRWPLYPLAYGAEAAARLTGKEPFLTVDGLNMSRYR 296 Query 298 ADVDHGKAVRELGWQPRPVEESIREAARFWAAMRTVGK 335 KA +ELG+QPRP +E +R+A ++ A +G+ Sbjct 297 MFFTSDKARKELGYQPRPYQEGLRDALAWFRAHGYLGR 334 >gi|162147410|ref|YP_001601871.1| dihydroflavonol-4-reductase [Gluconacetobacter diazotrophicus PAl 5] gi|209543976|ref|YP_002276205.1| hopanoid-associated sugar epimerase [Gluconacetobacter diazotrophicus PAl 5] gi|161785987|emb|CAP55568.1| putative dihydroflavonol-4-reductase [Gluconacetobacter diazotrophicus PAl 5] gi|209531653|gb|ACI51590.1| hopanoid-associated sugar epimerase [Gluconacetobacter diazotrophicus PAl 5] Length=363 Score = 170 bits (431), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 118/319 (37%), Positives = 167/319 (53%), Gaps = 11/319 (3%) Query 1 MNAPKLVIGANGFLGSHVTRQLVADCAPQKGE-VRAMVRPAANTRSIDDLPLTRFHGDVF 59 M AP LV GA GF+GS V R L+ Q+G +R M R A+ +I DLP GD+ Sbjct 33 MTAPTLVTGATGFVGSAVARTLL-----QRGHSLRLMARKGADLTNIRDLPAELVEGDLS 87 Query 60 DTATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNVLDVATDASLRRFVFTSS 119 AT A+A+ GC V++ D R W+ DP+P+ NV G R ++ A DA + R V+ SS Sbjct 88 APATFADAVRGCRYVFHVAADYRLWVPDPAPMMTANVEGTRRLMLAAQDAGVERIVYCSS 147 Query 120 YATVGR-RRGHVATEEDRVDTRKVTP-YVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYG 177 A +G G V+ E+ V V Y RS+ AE VL+ + GLPAV + ST G Sbjct 148 VAALGLIGDGTVSDEDTPVHEHAVIGIYKRSKYRAEQEVLRLVRERGLPAVIVNPSTPVG 207 Query 178 GGDWGRTPHGAFIAGAVFGRLP-FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISE 236 D TP G I GR+P + G+ + V VDD A +LA ERGR GE+Y++ Sbjct 208 PRDIKPTPTGQMILDCAAGRMPAYVDTGVNI--VHVDDVAEGHVLALERGRAGEKYILGG 265 Query 237 RMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTELSLASVRMMRS 296 + L+++ + AD AGV PPR S+ V++ + + +R G ++ + M Sbjct 266 QNFLLRDLFAMTADIAGVRPPRVSLPQSVIWPVAVVSEWLSRGFGIAPRVTREMLAMSHK 325 Query 297 EADVDHGKAVRELGWQPRP 315 + KA RELG+ PRP Sbjct 326 KMFFSSAKAERELGYAPRP 344 Lambda K H 0.321 0.135 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 617544973600 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40