BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0143c Length=492 Score E Sequences producing significant alignments: (Bits) Value gi|15607285|ref|NP_214657.1| transmembrane protein [Mycobacteriu... 956 0.0 gi|289441515|ref|ZP_06431259.1| conserved membrane protein [Myco... 955 0.0 gi|344217961|gb|AEM98591.1| transmembrane protein [Mycobacterium... 954 0.0 gi|254366595|ref|ZP_04982639.1| conserved transmembrane protein ... 954 0.0 gi|31791321|ref|NP_853814.1| transmembrane protein [Mycobacteriu... 954 0.0 gi|289764259|ref|ZP_06523637.1| conserved transmembrane protein ... 954 0.0 gi|15839524|ref|NP_334561.1| chloride channel [Mycobacterium tub... 949 0.0 gi|308231475|ref|ZP_07412565.2| conserved membrane protein [Myco... 916 0.0 gi|240168148|ref|ZP_04746807.1| chloride channel [Mycobacterium ... 697 0.0 gi|183980384|ref|YP_001848675.1| hypothetical protein MMAR_0353 ... 689 0.0 gi|118468313|ref|YP_890678.1| chloride channel [Mycobacterium sm... 558 7e-157 gi|111022868|ref|YP_705840.1| chloride channel transporter [Rhod... 424 3e-116 gi|226365376|ref|YP_002783159.1| ClC chloride channel [Rhodococc... 414 2e-113 gi|256371826|ref|YP_003109650.1| Chloride channel core [Acidimic... 385 1e-104 gi|260893297|ref|YP_003239394.1| Cl- channel voltage-gated famil... 368 2e-99 gi|48478228|ref|YP_023934.1| chloride channel protein [Picrophil... 346 5e-93 gi|298250257|ref|ZP_06974061.1| Cl- channel voltage-gated family... 341 2e-91 gi|159040763|ref|YP_001540015.1| chloride channel protein [Caldi... 334 2e-89 gi|313836438|gb|EFS74152.1| chloride transporter, chloride chann... 331 1e-88 gi|70607440|ref|YP_256310.1| voltage-gated chloride channel [Sul... 328 2e-87 gi|297626782|ref|YP_003688545.1| chloride channel [Propionibacte... 327 2e-87 gi|195952958|ref|YP_002121248.1| chloride channel core protein [... 327 3e-87 gi|315081434|gb|EFT53410.1| chloride transporter, chloride chann... 326 6e-87 gi|50843687|ref|YP_056914.1| putative chloride channel [Propioni... 326 6e-87 gi|314960954|gb|EFT05055.1| chloride transporter, chloride chann... 326 7e-87 gi|313794116|gb|EFS42136.1| chloride transporter, chloride chann... 326 7e-87 gi|327334431|gb|EGE76142.1| chloride channel [Propionibacterium ... 325 8e-87 gi|315105319|gb|EFT77295.1| chloride transporter, chloride chann... 325 9e-87 gi|335278658|gb|AEH30563.1| chloride transporter, ClC family pro... 325 9e-87 gi|313803237|gb|EFS44433.1| chloride transporter, chloride chann... 325 9e-87 gi|340774746|gb|EGR97221.1| chloride transporter, ClC family [Pr... 325 1e-86 gi|289428153|ref|ZP_06429852.1| chloride transporter, ClC family... 324 2e-86 gi|315095202|gb|EFT67178.1| chloride transporter, chloride chann... 323 4e-86 gi|314922017|gb|EFS85848.1| chloride transporter, chloride chann... 323 5e-86 gi|282854535|ref|ZP_06263871.1| chloride transporter, ClC family... 322 8e-86 gi|314965973|gb|EFT10072.1| chloride transporter, chloride chann... 322 1e-85 gi|257075702|ref|ZP_05570063.1| chloride channel protein [Ferrop... 313 6e-83 gi|314985929|gb|EFT30021.1| chloride transporter, chloride chann... 311 2e-82 gi|15899904|ref|NP_344509.1| hypothetical protein SSO3202 [Sulfo... 305 2e-80 gi|284175185|ref|ZP_06389154.1| hypothetical protein Ssol98_1113... 303 4e-80 gi|238620607|ref|YP_002915433.1| Chloride channel core [Sulfolob... 302 1e-79 gi|229585644|ref|YP_002844146.1| Chloride channel core [Sulfolob... 301 2e-79 gi|229580056|ref|YP_002838456.1| Chloride channel core [Sulfolob... 301 2e-79 gi|323475488|gb|ADX86094.1| Chloride channel core [Sulfolobus is... 300 3e-79 gi|323478210|gb|ADX83448.1| Chloride channel core [Sulfolobus is... 300 3e-79 gi|284998669|ref|YP_003420437.1| Cl- channel, voltage-gated fami... 300 3e-79 gi|13540925|ref|NP_110613.1| chloride channel protein [Thermopla... 300 4e-79 gi|229581283|ref|YP_002839682.1| Chloride channel core [Sulfolob... 298 1e-78 gi|227828415|ref|YP_002830195.1| chloride channel core [Sulfolob... 298 1e-78 gi|227831171|ref|YP_002832951.1| Chloride channel core [Sulfolob... 297 4e-78 >gi|15607285|ref|NP_214657.1| transmembrane protein [Mycobacterium tuberculosis H37Rv] gi|148659907|ref|YP_001281430.1| chloride channel [Mycobacterium tuberculosis H37Ra] gi|148821335|ref|YP_001286089.1| transmembrane protein [Mycobacterium tuberculosis F11] 40 more sequence titles Length=492 Score = 956 bits (2471), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/492 (100%), Positives = 492/492 (100%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|289441515|ref|ZP_06431259.1| conserved membrane protein [Mycobacterium tuberculosis T46] gi|289748618|ref|ZP_06507996.1| conserved membrane protein [Mycobacterium tuberculosis T92] gi|289756206|ref|ZP_06515584.1| transmembrane protein [Mycobacterium tuberculosis EAS054] gi|289414434|gb|EFD11674.1| conserved membrane protein [Mycobacterium tuberculosis T46] gi|289689205|gb|EFD56634.1| conserved membrane protein [Mycobacterium tuberculosis T92] gi|289696793|gb|EFD64222.1| transmembrane protein [Mycobacterium tuberculosis EAS054] Length=492 Score = 955 bits (2468), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/492 (99%), Positives = 492/492 (100%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTN+TIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNITIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|344217961|gb|AEM98591.1| transmembrane protein [Mycobacterium tuberculosis CTRI-2] Length=492 Score = 954 bits (2466), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/492 (99%), Positives = 491/492 (99%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAA VGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAATVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|254366595|ref|ZP_04982639.1| conserved transmembrane protein [Mycobacterium tuberculosis str. Haarlem] gi|134152107|gb|EBA44152.1| conserved transmembrane protein [Mycobacterium tuberculosis str. Haarlem] Length=492 Score = 954 bits (2466), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/492 (99%), Positives = 491/492 (99%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 G CSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GLCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|31791321|ref|NP_853814.1| transmembrane protein [Mycobacterium bovis AF2122/97] gi|121636055|ref|YP_976278.1| putative transmembrane protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988528|ref|YP_002643215.1| putative transmembrane protein [Mycobacterium bovis BCG str. Tokyo 172] 8 more sequence titles Length=492 Score = 954 bits (2466), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/492 (99%), Positives = 491/492 (99%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGR GVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|289764259|ref|ZP_06523637.1| conserved transmembrane protein [Mycobacterium tuberculosis GM 1503] gi|289711765|gb|EFD75781.1| conserved transmembrane protein [Mycobacterium tuberculosis GM 1503] Length=492 Score = 954 bits (2465), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/492 (99%), Positives = 492/492 (100%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMI+VAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIVVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|15839524|ref|NP_334561.1| chloride channel [Mycobacterium tuberculosis CDC1551] gi|13879634|gb|AAK44375.1| chloride channel [Mycobacterium tuberculosis CDC1551] Length=492 Score = 949 bits (2453), Expect = 0.0, Method: Compositional matrix adjust. Identities = 489/492 (99%), Positives = 489/492 (99%), Gaps = 0/492 (0%) Query 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL Sbjct 1 MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGL 60 Query 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI Sbjct 61 GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI 120 Query 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA Sbjct 121 VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA 180 Query 181 GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG 240 GFCSLLTRRLNLSNEDGRTAVALG AGIGAIF APLGGAALGASIPYRDDFDYRNLLPG Sbjct 181 GFCSLLTRRLNLSNEDGRTAVALGTRAGIGAIFVAPLGGAALGASIPYRDDFDYRNLLPG 240 Query 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS Sbjct 241 FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS 300 Query 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL Sbjct 301 VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL 360 Query 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM Sbjct 361 PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM 420 Query 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE Sbjct 421 ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE 480 Query 481 AERGGSDRPTTA 492 AERGGSDRPTTA Sbjct 481 AERGGSDRPTTA 492 >gi|308231475|ref|ZP_07412565.2| conserved membrane protein [Mycobacterium tuberculosis SUMu001] gi|308369311|ref|ZP_07417310.2| conserved membrane protein [Mycobacterium tuberculosis SUMu002] gi|308371597|ref|ZP_07425450.2| conserved membrane protein [Mycobacterium tuberculosis SUMu004] 11 more sequence titles Length=474 Score = 916 bits (2368), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/474 (100%), Positives = 474/474 (100%), Gaps = 0/474 (0%) Query 19 MPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLG 78 MPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLG Sbjct 1 MPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLG 60 Query 79 YLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIE 138 YLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIE Sbjct 61 YLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIE 120 Query 139 SVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGR 198 SVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGR Sbjct 121 SVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGR 180 Query 199 TAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFD 258 TAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFD Sbjct 181 TAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFD 240 Query 259 PLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIG 318 PLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIG Sbjct 241 PLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIG 300 Query 319 GLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSG 378 GLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSG Sbjct 301 GLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSG 360 Query 379 GLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVA 438 GLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVA Sbjct 361 GLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVA 420 Query 439 EMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA 492 EMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA Sbjct 421 EMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA 474 >gi|240168148|ref|ZP_04746807.1| chloride channel [Mycobacterium kansasii ATCC 12478] Length=482 Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/459 (88%), Positives = 428/459 (94%), Gaps = 0/459 (0%) Query 17 PTMPEAEDIGNEAAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFL 76 P E + AAGGRFG SIRSAGYLRKW LLG+TIGVIAGLGAVVFYLALKYT EFL Sbjct 6 PDALEPREAPLAAAGGRFGASIRSAGYLRKWLLLGVTIGVIAGLGAVVFYLALKYTGEFL 65 Query 77 LGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEA 136 LGYLADY IPTP+GEGG RGS+GFARPWAIPLVTTGGA+LSA IVA+ APEATGHGTDEA Sbjct 66 LGYLADYHIPTPLGEGGSRGSSGFARPWAIPLVTTGGALLSAFIVARFAPEATGHGTDEA 125 Query 137 IESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNED 196 IE+VH DPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRL LS+ED Sbjct 126 IEAVHTDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLGLSDED 185 Query 197 GRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLG 256 GR AVALGIGAGIGAIFAAPLGGA L ASI YRDDFDYR+LLPGFI SGTAYAVLGAFLG Sbjct 186 GRIAVALGIGAGIGAIFAAPLGGAVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFLG 245 Query 257 FDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPA 316 FDPLFGYIDAEYRFE+AWPLLWFVVIGL+AAAVGYLYAR+FHASVA+TRRLPGG V+KP Sbjct 246 FDPLFGYIDAEYRFERAWPLLWFVVIGLVAAAVGYLYARIFHASVALTRRLPGGSVIKPT 305 Query 317 IGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGG 376 +GGLLVGLLGL IPQILSSGYGWAQLAADRG+L+SIPLWI++VLPIAKI+ATSLSIGTGG Sbjct 306 VGGLLVGLLGLLIPQILSSGYGWAQLAADRGSLMSIPLWIIVVLPIAKIIATSLSIGTGG 365 Query 377 SGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIM 436 SGGLFGPGIVIGAFVGAA+WRLGEL+ +PGVP PGIFVVV MMACFGSV+RAPLA+MIM Sbjct 366 SGGLFGPGIVIGAFVGAAVWRLGELSGIPGVPDAPGIFVVVGMMACFGSVARAPLAIMIM 425 Query 437 VAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLN 475 VAEMTGSFSVVPGAI+AVGIAALL+SRTNVTIYE QRLN Sbjct 426 VAEMTGSFSVVPGAILAVGIAALLMSRTNVTIYEAQRLN 464 >gi|183980384|ref|YP_001848675.1| hypothetical protein MMAR_0353 [Mycobacterium marinum M] gi|183173710|gb|ACC38820.1| conserved hypothetical transmembrane protein [Mycobacterium marinum M] Length=468 Score = 689 bits (1779), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/447 (88%), Positives = 419/447 (94%), Gaps = 0/447 (0%) Query 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 AAGGRFG SIR+AGYL+KWFLLGITIG IAGLGAVVFYLALKYT EFLLGYLADY IPTP Sbjct 5 AAGGRFGASIRNAGYLQKWFLLGITIGGIAGLGAVVFYLALKYTGEFLLGYLADYHIPTP 64 Query 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 Query 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCS LTRRL LS+EDGRTAVALGIGAG Sbjct 125 SRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSFLTRRLGLSDEDGRTAVALGIGAG 184 Query 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 IGAIFAAPLGGA L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct 185 IGAIFAAPLGGAVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 Query 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 RFEKAWPLLWFVVIG++AAA+GYLYARVFHASV + RLPGGPV+KPA+GGLLVGL+GL Sbjct 245 RFEKAWPLLWFVVIGVVAAAIGYLYARVFHASVGLAHRLPGGPVIKPAVGGLLVGLMGLL 304 Query 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKILATSLSIGTGGSGGLFGPGIVIG Sbjct 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKILATSLSIGTGGSGGLFGPGIVIG 364 Query 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 Query 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 >gi|118468313|ref|YP_890678.1| chloride channel [Mycobacterium smegmatis str. MC2 155] gi|118169600|gb|ABK70496.1| chloride channel [Mycobacterium smegmatis str. MC2 155] Length=458 Score = 558 bits (1439), Expect = 7e-157, Method: Compositional matrix adjust. Identities = 308/450 (69%), Positives = 367/450 (82%), Gaps = 0/450 (0%) Query 32 GRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGE 91 G G +R++GY+RKW +LGI IGVIAGLGAVVFYLAL LLGYL Y IP P G+ Sbjct 9 GGLGNFVRNSGYVRKWLILGIAIGVIAGLGAVVFYLALDGAGRVLLGYLGGYDIPKPSGD 68 Query 92 GGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRA 151 GG+ GS GF RPWAIPL++ GGA++SA VAK APEA GHGTD+AIE+VH DPR IR RA Sbjct 69 GGNPGSPGFDRPWAIPLISCGGALVSAWFVAKFAPEAEGHGTDDAIEAVHTDPRKIRVRA 128 Query 152 VLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGA 211 ++VK +ASALTIGSGGSGGREGP A ISAGF SLLTR LNLS+EDGR AV+LGIGAGIGA Sbjct 129 IVVKTIASALTIGSGGSGGREGPAAHISAGFGSLLTRWLNLSDEDGRLAVSLGIGAGIGA 188 Query 212 IFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFE 271 IF APLGGA L ASI YRDDFDYR L+PGFI S +AYAVLG+ LGFDPLFG++ +YRF Sbjct 189 IFGAPLGGAVLAASIVYRDDFDYRALIPGFITSASAYAVLGSILGFDPLFGFLVGDYRFG 248 Query 272 KAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQ 331 +A L WFVV+G+IA VG+LYARVF+ +VA+T+ LPGG ++KPA+GGL VGL+ L IPQ Sbjct 249 QALDLAWFVVLGVIAGGVGWLYARVFYGTVAVTKMLPGGKIVKPALGGLAVGLMALAIPQ 308 Query 332 ILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFV 391 +L+SGYGWA+ AA TL++IPLWIV+VLP+AKI+ATSLSIGTGGSGG+FGPG+VIGAFV Sbjct 309 VLASGYGWAEKAAATETLMNIPLWIVLVLPVAKIVATSLSIGTGGSGGIFGPGVVIGAFV 368 Query 392 GAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAI 451 GAA+WRLG+ LPG+P P IFVVV MMACFG V+ APLAVMIMV EMT SF+V+P A+ Sbjct 369 GAALWRLGDALALPGIPDSPAIFVVVGMMACFGCVAHAPLAVMIMVCEMTSSFAVIPCAM 428 Query 452 IAVGIAALLLSRTNVTIYETQRLNRQTAEA 481 + VG+A L +SR++V IY QR R+ A Sbjct 429 VGVGVACLTISRSDVAIYRAQRARREPEPA 458 >gi|111022868|ref|YP_705840.1| chloride channel transporter [Rhodococcus jostii RHA1] gi|110822398|gb|ABG97682.1| chloride channel transporter [Rhodococcus jostii RHA1] Length=464 Score = 424 bits (1089), Expect = 3e-116, Method: Compositional matrix adjust. Identities = 268/443 (61%), Positives = 336/443 (76%), Gaps = 1/443 (0%) Query 38 IRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGS 97 IR++GY RKW +LG+ IG++AGLGAVVFY+AL+ ++ L+ + Y PT G+GG GS Sbjct 19 IRTSGYTRKWLVLGVVIGIVAGLGAVVFYVALREATQLLIVGIGGYTPPTAAGDGGAVGS 78 Query 98 TGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMV 157 F RPWAIPLV G ++S +IV LAPEA GHGTD AI++VH DPR IR R VLVK+V Sbjct 79 REFTRPWAIPLVVCLGGLVSGIIVFTLAPEAEGHGTDAAIDAVHRDPRMIRVRVVLVKLV 138 Query 158 ASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPL 217 ASA+TIGSGGSGGREGPTAQISAGF SLL RRL+LS DGR AVA+GIG+GIGAIF APL Sbjct 139 ASAITIGSGGSGGREGPTAQISAGFGSLLARRLDLSPRDGRIAVAIGIGSGIGAIFGAPL 198 Query 218 GGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLL 277 GGA L +IPY++DFD+ L+P + S +Y V G+FLGF PLFGY +Y F+ L+ Sbjct 199 GGAVLCCTIPYKEDFDFEVLVPALVTSIVSYTVFGSFLGFGPLFGYAAQDYVFDTPVQLV 258 Query 278 WFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGY 337 WF +IG++ +G LY+ F+ +V +T RLPG ++KPA+GGLLVGL+ L +P++L SGY Sbjct 259 WFALIGVLGGLIGLLYSGTFYTAVDLTHRLPGSRIVKPAVGGLLVGLMALVLPEVLGSGY 318 Query 338 GWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWR 397 GW Q + RG L +IPLW+V++LP AKILATSLSIG+GGSGG+FGPG+VIGAF GAA+WR Sbjct 319 GWIQQSMARGDLTAIPLWVVLLLPFAKILATSLSIGSGGSGGIFGPGMVIGAFTGAAVWR 378 Query 398 LGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIA 457 L E PGVP P FV+V MMACFGS++RAPLAVM+MVAEMTGS V+ +IAVG+A Sbjct 379 LLEPIA-PGVPDNPAPFVIVGMMACFGSIARAPLAVMLMVAEMTGSVGVLVPGMIAVGLA 437 Query 458 ALLLSRTNVTIYETQRLNRQTAE 480 L++ R+ TIY QR NR A Sbjct 438 YLIVRRSGKTIYRAQRENRAEAR 460 >gi|226365376|ref|YP_002783159.1| ClC chloride channel [Rhodococcus opacus B4] gi|226243866|dbj|BAH54214.1| putative ClC chloride channel [Rhodococcus opacus B4] Length=470 Score = 414 bits (1064), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 271/454 (60%), Positives = 337/454 (75%), Gaps = 1/454 (0%) Query 31 GGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVG 90 G G IRSAGY RKW +LG+ IG++AGLGAVVFY+AL ++ L+ + Y PT G Sbjct 15 GASAGAWIRSAGYTRKWLVLGVVIGIVAGLGAVVFYVALSEATQLLIVDIGGYHPPTAAG 74 Query 91 EGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGR 150 +GG GS F RPWAIPLV G ++S ++V LAPEA GHGTD AIE+VH DPR IR R Sbjct 75 DGGAGGSREFTRPWAIPLVVCLGGLVSGILVFTLAPEAEGHGTDAAIEAVHRDPRMIRVR 134 Query 151 AVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIG 210 VLVK+VASA+TIGSGGSGGREGPTAQISAGF SLL RRLNLS DGR AVA+GIG+GIG Sbjct 135 VVLVKLVASAITIGSGGSGGREGPTAQISAGFGSLLARRLNLSPRDGRIAVAIGIGSGIG 194 Query 211 AIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRF 270 AIF APLGGA L +IPY++DFD+ L+P + S +Y V G+FLGF PLFGY +Y F Sbjct 195 AIFGAPLGGAVLCCTIPYKEDFDFEVLVPALVTSIVSYTVFGSFLGFGPLFGYAAQDYVF 254 Query 271 EKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIP 330 + L+WF +IG++ +G LY+ F+ +V +T RLPG ++KPA+GGLLVGL+ L +P Sbjct 255 DTPAQLVWFALIGVLGGLIGLLYSGTFYTAVDLTHRLPGSRIVKPAVGGLLVGLMALVLP 314 Query 331 QILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAF 390 ++L SGYGW Q + R L +IPLW+V++LP AKILATSLSIG+GGSGG+FGPG+VIGAF Sbjct 315 EVLGSGYGWIQQSMARDDLAAIPLWVVLLLPFAKILATSLSIGSGGSGGIFGPGMVIGAF 374 Query 391 VGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGA 450 GAA+WRL E PGVP P FV+V MMACFGS++RAPLAVM+MVAEMTGS V+ Sbjct 375 TGAAVWRLLEPIA-PGVPDNPAPFVIVGMMACFGSIARAPLAVMLMVAEMTGSIGVLVPG 433 Query 451 IIAVGIAALLLSRTNVTIYETQRLNRQTAEAERG 484 +IAVG++ L++ R+ TIY Q NR A +G Sbjct 434 MIAVGLSYLIVRRSGKTIYRAQLENRAVARLAQG 467 >gi|256371826|ref|YP_003109650.1| Chloride channel core [Acidimicrobium ferrooxidans DSM 10331] gi|256008410|gb|ACU53977.1| Chloride channel core [Acidimicrobium ferrooxidans DSM 10331] Length=453 Score = 385 bits (988), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 247/440 (57%), Positives = 313/440 (72%), Gaps = 5/440 (1%) Query 38 IRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGS 97 +R L + +L I +GVIAG GAV+FY AL + + L LA YQ+PTP GEG GS Sbjct 11 LRRQPTLLRRVILAIALGVIAGAGAVIFYAALTFATHEFLAVLAGYQVPTPAGEGNAPGS 70 Query 98 TGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMV 157 +ARPWAIPL GA+ + ++V LAPEA GHGTD AI++V DPR IR RAV+VK++ Sbjct 71 LHYARPWAIPLSVVLGAIGAGMLVFTLAPEAEGHGTDAAIDAVLHDPRGIRLRAVVVKII 130 Query 158 ASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPL 217 ASALTIGSGGSGGREGPTAQISAGF SLL R L+L EDGR AV++GIG+GIGAIF APL Sbjct 131 ASALTIGSGGSGGREGPTAQISAGFGSLLARVLDLGTEDGRVAVSVGIGSGIGAIFGAPL 190 Query 218 GGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLL 277 GGA L A I YRDDF+Y LLPG +AS A A+ A GF PLF + + L+ Sbjct 191 GGAVLAAEIVYRDDFEYEALLPGLLASLIASAIFDAVYGFRPLFA-VAGHFELTTPLTLV 249 Query 278 WFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGY 337 WF ++G++A A+G LYAR F+ +V + RRLP +PAIGGLLVGLL L +P++L +GY Sbjct 250 WFAIVGVVAGAIGLLYARSFYGTVRLARRLPIPRHFRPAIGGLLVGLLALWLPEVLGTGY 309 Query 338 GWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWR 397 GW Q +L PL +++VLPIA+I+ATSLSIGTGGSGG+FGPG+VIGAF G A+WR Sbjct 310 GWVQKGLS-DQMLHTPLLVIVVLPIARIVATSLSIGTGGSGGVFGPGMVIGAFTGLAVWR 368 Query 398 LGELTEL-PGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGI 456 + L L P + H+ FVVV MMA FG +SRAP+AVM+MVAEMTG+ +++ A+IAV I Sbjct 369 I--LAPLVPAIGHDASAFVVVGMMAMFGGISRAPIAVMLMVAEMTGTIALLGPAMIAVAI 426 Query 457 AALLLSRTNVTIYETQRLNR 476 A L++ + +IY +Q R Sbjct 427 AWLIVKAVDDSIYRSQLPTR 446 >gi|260893297|ref|YP_003239394.1| Cl- channel voltage-gated family protein [Ammonifex degensii KC4] gi|260865438|gb|ACX52544.1| Cl- channel voltage-gated family protein [Ammonifex degensii KC4] Length=598 Score = 368 bits (944), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 216/443 (49%), Positives = 289/443 (66%), Gaps = 12/443 (2%) Query 43 YLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFAR 102 YL KW L+ +IG +AG+GA+VFY A+ + L A + P +GEG T +R Sbjct 15 YLAKWLLIAGSIGAVAGVGAIVFYEAIHLFTYLFLNLGAGFHPPEALGEG-QPVVTEISR 73 Query 103 PWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALT 162 W IP+VTT G +LS LIV K APEA GHGTD AI++ H IR R LVK++ASA+T Sbjct 74 RWMIPVVTTLGGLLSGLIVFKFAPEAEGHGTDAAIDAFHHKEGIIRARVPLVKIIASAIT 133 Query 163 IGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAAL 222 IGSGGS GREGPTAQI+AGF S++ + L L+ D A+A GIGAGIGAIF APLGGA L Sbjct 134 IGSGGSAGREGPTAQIAAGFGSIMGQLLKLNTRDRCIALATGIGAGIGAIFKAPLGGALL 193 Query 223 GASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVI 282 I Y + F+ + L+P FIAS Y + ++ G+ P+FG++ F+ LL++ ++ Sbjct 194 STEILYLEGFEVQALVPSFIASLIGYTIFASYAGYMPVFGWMSQNIAFDPV-TLLYYALL 252 Query 283 GLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 G++ +G LY + F+A+ +++ LKPA GGLLVG++GL +PQ+L GYGW QL Sbjct 253 GVLCGLIGILYTKTFYATRNFFKKINLPKWLKPAAGGLLVGIMGLFLPQVLGMGYGWLQL 312 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRL--GE 400 L PL IV++L AKILATSL+IG+GGSGG+F PG+ IG VG A+W+L G Sbjct 313 GMLNKPL---PLDIVVLLIFAKILATSLTIGSGGSGGVFAPGLFIGGMVGTALWQLLHGM 369 Query 401 LTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALL 460 + LP P F+VV MMA FG+V+ APLAVM MV EMTGS++++ A+IAVGIA +L Sbjct 370 VGHLPASPQP---FIVVGMMALFGAVAHAPLAVMFMVGEMTGSYTMLVPAMIAVGIAYVL 426 Query 461 LSRTNVTIYETQRLNRQTAEAER 483 + N TIYE+Q + A R Sbjct 427 VG--NNTIYESQVPTPADSPAHR 447 >gi|48478228|ref|YP_023934.1| chloride channel protein [Picrophilus torridus DSM 9790] gi|48430876|gb|AAT43741.1| chloride channel protein [Picrophilus torridus DSM 9790] Length=590 Score = 346 bits (888), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 199/466 (43%), Positives = 280/466 (61%), Gaps = 17/466 (3%) Query 33 RFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEG 92 R + S Y KWF++G+ IG+I+GLGA +FY ++++ L + +P P+GE Sbjct 3 RISFKLSSLPYFEKWFIMGLIIGIISGLGATIFYFSIRFFEYIFLARIVGTNLPRPLGEN 62 Query 93 GHRGSTGFA-RPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRA 151 G +A R + IP+V GA +S+ IV + APEA GHGTD AI S H + IR R Sbjct 63 GSLIYHFYALRFYLIPVVLIAGAAISSFIVQRFAPEAEGHGTDSAIRSFHYNYGKIRRRI 122 Query 152 VLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGA 211 +VK +ASA+TIGSGGS GREGPTAQI+AG S + L L+ D R AVA+GIG+GIG Sbjct 123 PVVKTIASAITIGSGGSAGREGPTAQIAAGLGSFIADLLGLTPRDRRIAVAVGIGSGIGT 182 Query 212 IFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFE 271 IF AP+GGA LGA I YR D + L P +A+ Y++ + +GF+P+FGY + Sbjct 183 IFKAPIGGAVLGAEILYRRDMETEVLFPSIVAASVGYSIFASIVGFEPIFGYYLLPF--- 239 Query 272 KAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQ 331 L ++ +GLI Y R F+ + +RL P KP IG G++ L P+ Sbjct 240 NPLRLPFYATLGLITGLFAIFYVRFFYGTRDFFKRLNLSPYYKPIIGAAFTGIIALFFPE 299 Query 332 ILSSGYGWAQLAA----DRGTLLSIPLWIVIV-LPIAKILATSLSIGTGGSGGLFGPGIV 386 +LS+GYGW QL + +PL I +V LP K+ ATS ++ +GGSGG+F PGI Sbjct 300 VLSTGYGWVQLLEYGRFNEFVYYGMPLVIFLVFLPFMKVFATSFTVASGGSGGVFAPGIF 359 Query 387 IGAFVGAAIWRLGELTELPGVPH-EPGI--FVVVAMMACFGSVSRAPLAVMIMVAEMTGS 443 IGA +GA LG L L G P+ P I FV++ M++ FG+ +APL+V++MV EMTGS Sbjct 360 IGASLGAL---LGYLVHL-GFPYIAPNIAPFVIIGMLSFFGAAGKAPLSVILMVVEMTGS 415 Query 444 FSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA++AV I + ++S T +IYE+Q L R+ + A G P Sbjct 416 LQLLPGAMLAVAI-SYIVSGTKYSIYESQVLTRRDSPANMGEFSSP 460 >gi|298250257|ref|ZP_06974061.1| Cl- channel voltage-gated family protein [Ktedonobacter racemifer DSM 44963] gi|297548261|gb|EFH82128.1| Cl- channel voltage-gated family protein [Ktedonobacter racemifer DSM 44963] Length=699 Score = 341 bits (874), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 234/450 (52%), Positives = 300/450 (67%), Gaps = 9/450 (2%) Query 37 SIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRG 96 S S YL KW L+ IG++AG+GA+ FY A+ + ++F LG L Y P+P GEGG Sbjct 22 SFESPRYLLKWLLISTLIGLVAGVGAIAFYAAIHFATDFFLGRLIGYLPPSPAGEGGQTT 81 Query 97 STGF---ARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVL 153 F RPW +P+VTT GA++S +IV LAPEA GHGTD AI + H + +AIR R L Sbjct 82 VMSFWSATRPWLLPVVTTLGALISGIIVFNLAPEAEGHGTDAAIAAFH-EGKAIRARIPL 140 Query 154 VKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIF 213 VK+VASA+TIG+GGS GREGP AQISAGF S+L L L +D R A+A GIGAGIGAIF Sbjct 141 VKLVASAITIGTGGSAGREGPAAQISAGFGSILANVLRLDVQDRRIALATGIGAGIGAIF 200 Query 214 AAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKA 273 APLGGA L A I Y+DD + ++P +AS Y+V GA+ G+ P+F F Sbjct 201 RAPLGGAILAAEILYKDDLEVETIIPALMASIIGYSVFGAWSGWQPIFA-TPPNLAFTSP 259 Query 274 WPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQIL 333 LL++VV+G++ +G LYAR F+ I RL KP IGGLLVGL+GL +PQ L Sbjct 260 PQLLYYVVLGVLCGLLGLLYARGFYGITHIFHRLKLPKWFKPGIGGLLVGLIGLVMPQAL 319 Query 334 SSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGA 393 GYGW Q++ G LLS+PLW++++LP AKIL T LSIG+GGSGG+FGPG+VIG VGA Sbjct 320 GMGYGWVQVSMGAG-LLSLPLWVILLLPFAKILTTGLSIGSGGSGGIFGPGMVIGGMVGA 378 Query 394 AIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIA 453 WRL PG+P P FV+V MMA FG ++ APLAVM+MVAEMTG+ S++ A+IA Sbjct 379 CFWRLCYHV-FPGLPATPAPFVIVGMMALFGGIAHAPLAVMLMVAEMTGNLSMLAPAMIA 437 Query 454 VGIAALLLSRTNVTIYETQRLNRQTAEAER 483 VGIA +L+ T T+Y +Q R + A R Sbjct 438 VGIATILVGGT--TMYTSQVPTRADSPAHR 465 >gi|159040763|ref|YP_001540015.1| chloride channel protein [Caldivirga maquilingensis IC-167] gi|157919598|gb|ABW01025.1| Chloride channel core [Caldivirga maquilingensis IC-167] Length=586 Score = 334 bits (857), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 208/461 (46%), Positives = 277/461 (61%), Gaps = 13/461 (2%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHR 95 ++I Y KWF+LGI IGV+AGL A+ FY LK+ + L ++ P P+GEGG Sbjct 1 MNISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSL 60 Query 96 GSTGFA-RPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLV 154 A R W IP+ T G +LS LIV APEA GHGTD AI + H IR R + Sbjct 61 NYVLHAGRLWLIPVSTALGGLLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRIPPI 120 Query 155 KMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFA 214 K++ASA+TIGSGGS GREGPTAQ+SAG S + L LS ED R AVA+GIGAGIG+IF Sbjct 121 KLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSAEDRRIAVAVGIGAGIGSIFK 180 Query 215 APLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAW 274 AP+GGA L A + Y+ D + L P +AS Y++ + +GF P+FGY + + Sbjct 181 APMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVFNPLR-- 238 Query 275 PLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILS 334 L + V+G++ V LY + F+ +R +KP IGGL GL+GL +P+IL Sbjct 239 -LPLYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPEILG 297 Query 335 SGYGWAQLAADRGT------LLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 +GYGW LA +L PL I+I+LP KI+ATS ++G+GGSGG+F PGIVIG Sbjct 298 TGYGWVNLAEFNNVNAFASPVLIPPLMILILLPFLKIIATSFTVGSGGSGGVFAPGIVIG 357 Query 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 AF G W L PG+ P FV+V+M+A FG+ ++APLAVM MV EMTGS+ ++P Sbjct 358 AFTGFDAWLLFHYLT-PGLTPNPAPFVIVSMLALFGASAKAPLAVMFMVIEMTGSYQLLP 416 Query 449 GAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 A+IAV IA ++ + TIY Q R+ + A P Sbjct 417 AAMIAVAIAYIV--SGDYTIYRAQVPTRRDSPAHANEYKVP 455 >gi|313836438|gb|EFS74152.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL037PA2] gi|314929051|gb|EFS92882.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL044PA1] gi|314971003|gb|EFT15101.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL037PA3] gi|328906664|gb|EGG26439.1| putative chloride channel [Propionibacterium humerusii P08] Length=573 Score = 331 bits (849), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 213/434 (50%), Positives = 293/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ L+ + +LL L Y P +GEGG STG RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLETGTHWLLETLGSYTPPGTLGEGGGATSTGPTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPLV TGGA++S ++V +AP A GHGTD AI +VH DP A++G+ VK++ASAL I Sbjct 97 WAIPLVVTGGALVSGILVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASALVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG ++ +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLNG-VQFSEPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF+ + L P L PAIGGL VGLL L IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYGGTKLFESLNKVPGWLIPAIGGLGVGLLDLAIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WR+ L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRI--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFGSV+ APL +++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGSVAHAPLGMLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 N +IY +Q +R Sbjct 454 --NTSIYTSQLKDR 465 >gi|70607440|ref|YP_256310.1| voltage-gated chloride channel [Sulfolobus acidocaldarius DSM 639] gi|68568088|gb|AAY81017.1| voltage-gated chloride channel [Sulfolobus acidocaldarius DSM 639] Length=587 Score = 328 bits (840), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 197/462 (43%), Positives = 273/462 (60%), Gaps = 16/462 (3%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHR 95 + + S Y KWF+LG+ +G+IAGL A FYL L L L IP P+GEGG Sbjct 1 MKLSSLPYFEKWFILGVILGIIAGLAATAFYLLLHVFEGLFLYSLVSISIPKPLGEGGSL 60 Query 96 G---STGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAV 152 S+G R + IPL G +LS LIV APEA GHGTD AI++ H I+ V Sbjct 61 NFVFSSG--RYYLIPLSVALGGLLSGLIVYTFAPEAEGHGTDAAIKAYHYYQGKIKWIVV 118 Query 153 LVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAI 212 VK++ASA+TIGSGGS GREGPTAQ SAG S++ L LS ED R AVA+GIGAGIG I Sbjct 119 PVKIIASAITIGSGGSAGREGPTAQFSAGVGSIIADLLKLSPEDRRKAVAVGIGAGIGTI 178 Query 213 FAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEK 272 F P+GGA L A I Y+ D + + P IAS Y + G+ GF+P+FGY + Sbjct 179 FKTPIGGAILAAEILYKRDIEPEVIYPTLIASAIGYTIFGSIFGFEPVFGYYTGSFN--- 235 Query 273 AWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQI 332 L + ++G+I+ + LY + F+ + ++L +KP IGGL+ G + L +P++ Sbjct 236 PLRLPMYAILGVISGLLAILYVKTFYGINSFFKKLKTKNYIKPLIGGLVSGAIALLVPEV 295 Query 333 LSSGYGWAQLAADR--GTLLS--IPLWIVIVL-PIAKILATSLSIGTGGSGGLFGPGIVI 387 + GYGW L + S +P ++++ L P KILATS SIG+G SGG+F PG+ I Sbjct 296 MGVGYGWINLVEYEKFSSFYSPILPFFVILALIPFLKILATSFSIGSGASGGVFAPGLFI 355 Query 388 GAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVV 447 GAF+GA + + L P + + FV++ MM+ F + +APL+V+IMV EMTGS ++ Sbjct 356 GAFMGADVGLVFHLL-FPTIVPDISPFVIIGMMSFFSAAGKAPLSVIIMVTEMTGSLQLL 414 Query 448 PGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 PGA+IAV I+ L+ N TIY+ Q R+ + A + P Sbjct 415 PGAMIAVAISYLI--SGNYTIYQAQVPTRRDSPAHLQEYETP 454 >gi|297626782|ref|YP_003688545.1| chloride channel [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] gi|296922547|emb|CBL57120.1| Chloride channel [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] Length=482 Score = 327 bits (839), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 226/446 (51%), Positives = 304/446 (69%), Gaps = 5/446 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 + +W L G+ IGV++GLGAV FY L + +++LL L Y PT GEG FARP Sbjct 42 MSRWLLFGVVIGVVSGLGAVGFYWCLSHATQWLLVDLGGYLPPTTRGEGTGFPGADFARP 101 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIP VT G A+++ ++VA +APEA GHGTD AI +VH +P +R RA LVK+VAS+L I Sbjct 102 WAIPAVTGGAALVAGILVACIAPEARGHGTDAAIAAVHHNPTGLRLRAALVKVVASSLII 161 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L L + D R AVA + +GIGAIF APLGGA LG Sbjct 162 GSGGSGGREGPTAQISATVISRLCGALRIPRPDARIAVAAAMASGIGAIFRAPLGGALLG 221 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++PG I+S A+AV G+ GF P+FG + F LLWF ++G Sbjct 222 AELLYRDDLEADAIMPGLISSIVAFAVYGSVYGFQPIFGTMSG-LTFVHPAELLWFALVG 280 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLA 343 + A +G YA+ F+A A+ +RLP + PAIGGL VGLLGL +P +L +GYGW QL Sbjct 281 VAAGLLGRWYAQAFYAGGALLQRLPVPRAILPAIGGLCVGLLGLAVPAVLGTGYGWTQLQ 340 Query 344 ADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTE 403 G +LS PLW+V+V+P AKI+AT+LSIG+GGSGG+FGPG+VIG GAA+WR+ + + Sbjct 341 MTSGWMLSAPLWLVLVIPFAKIVATTLSIGSGGSGGVFGPGMVIGGATGAALWRI--IHD 398 Query 404 LPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSR 463 +PGV P +V++ M+ACFG+++ APL VM+MVAEMTG+ S++ A+IAV IA +++ Sbjct 399 MPGVSSSPAPYVIIGMIACFGAIAHAPLGVMLMVAEMTGNLSLLAPAMIAVAIATMIVG- 457 Query 464 TNVTIYETQRLNRQTAEAERGGSDRP 489 + +I+ +Q NR A G+ P Sbjct 458 -DNSIFHSQLRNRLEAARLYRGTPAP 482 >gi|195952958|ref|YP_002121248.1| chloride channel core protein [Hydrogenobaculum sp. Y04AAS1] gi|195932570|gb|ACG57270.1| Chloride channel core [Hydrogenobaculum sp. Y04AAS1] Length=462 Score = 327 bits (839), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 191/459 (42%), Positives = 272/459 (60%), Gaps = 14/459 (3%) Query 33 RFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEG 92 + G I Y KWF+LG+ GV++GLGA+ FY +LK + Y IP+P GE Sbjct 7 KIGSFISRQDYFLKWFILGLINGVVSGLGALFFYYSLKLCEFIFFNKILHYHIPSPTGEE 66 Query 93 GHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAV 152 + + +P+V G ++ IV K APEA GHGTD AI++ H IR R + Sbjct 67 PNNLIFKPGLVYLLPIVIAFGGFIAGFIVFKWAPEAEGHGTDAAIDAYHNKKGFIRDRVI 126 Query 153 LVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAI 212 +K +ASA+TIGSGGS GREGPTA ISAG S L R L LS +D +ALGIGAGIG I Sbjct 127 FIKSIASAITIGSGGSAGREGPTALISAGIGSWLARLLGLSEKDRERMLALGIGAGIGTI 186 Query 213 FAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEK 272 F AP+GGA LGA I Y+ D N+ PG +AS Y++ G+ +GF P+FGY + Sbjct 187 FKAPIGGAILGAEILYKSDLQADNIFPGLVASAVGYSIFGSIVGFVPVFGYYLQNFN-PL 245 Query 273 AWPLLWFVVIGLIAAAVGYLYARVFHA-SVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQ 331 PL ++++G++ VG +YA+ F+ + + L LKP IG L G++G+ P+ Sbjct 246 RLPL--YIILGIVCGIVGRIYAKTFYYFKDNLFKSLKTNIYLKPVIGMFLTGIIGMAFPE 303 Query 332 ILSSGYGWAQLAADRGTLL----SIPLWIVIV-LPIAKILATSLSIGTGGSGGLFGPGIV 386 +L +GYGW Q A D + IPL+I V L KI+ATSL++G+G SGG+F PG+ Sbjct 304 VLGTGYGWLQGAIDTKFSMFDTYGIPLFIFFVLLAFIKIIATSLTVGSGASGGVFAPGLF 363 Query 387 IGAFVGAAIWRLGE--LTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 IG F+GA + + L H G FV+V M+A FG+ +AP+AV +MV EMTGS+ Sbjct 364 IGGFLGAGLGIVYHQLFPSLVNTSHIGG-FVIVGMLALFGAAGKAPVAVTLMVVEMTGSY 422 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAER 483 ++P ++AV +A L+ + +IY++Q R+ + A + Sbjct 423 QLLPACMLAVAVAYLI--SGDYSIYKSQVKTREDSPAYK 459 >gi|315081434|gb|EFT53410.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL078PA1] Length=575 Score = 326 bits (835), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|50843687|ref|YP_056914.1| putative chloride channel [Propionibacterium acnes KPA171202] gi|295131777|ref|YP_003582440.1| chloride transporter, ClC family [Propionibacterium acnes SK137] gi|335050350|ref|ZP_08543320.1| chloride transporter, ClC family [Propionibacterium sp. 409-HC1] 50 more sequence titles Length=575 Score = 326 bits (835), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|314960954|gb|EFT05055.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL002PA2] Length=575 Score = 326 bits (835), Expect = 7e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|313794116|gb|EFS42136.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL110PA1] gi|313839229|gb|EFS76943.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL086PA1] gi|314964012|gb|EFT08112.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL082PA1] gi|327457549|gb|EGF04204.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL092PA1] Length=575 Score = 326 bits (835), Expect = 7e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLKDR 465 >gi|327334431|gb|EGE76142.1| chloride channel [Propionibacterium acnes HL097PA1] Length=575 Score = 325 bits (834), Expect = 8e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|315105319|gb|EFT77295.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL050PA2] Length=576 Score = 325 bits (834), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|335278658|gb|AEH30563.1| chloride transporter, ClC family protein [Propionibacterium acnes 6609] Length=686 Score = 325 bits (834), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 148 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 207 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 208 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 267 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 268 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 327 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 328 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 386 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 387 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 446 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 447 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 504 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 505 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 564 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 565 DT--SIYTSQLKDR 576 >gi|313803237|gb|EFS44433.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL110PA2] Length=575 Score = 325 bits (834), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLPRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLKDR 465 >gi|340774746|gb|EGR97221.1| chloride transporter, ClC family [Propionibacterium acnes SK182B-JCVI] Length=577 Score = 325 bits (832), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 214/434 (50%), Positives = 294/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ L+ + +LL L Y P +GEGG T ARP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLETGTHWLLETLGSYTPPGTLGEGGGVTGTKLARP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPLV TGGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLVVTGGALVSGALVYFIAPTAKGHGTDNAIYAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+AV G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFAVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF+ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYGGTTLFDRLDKVPGWLVPAIGGLGVGLLGLIIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 TL+ +P+ +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WR+ L Sbjct 336 EMFADTLMRMPILMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRI--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFGSV+ APL +++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGSVAHAPLGMLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLRDR 465 >gi|289428153|ref|ZP_06429852.1| chloride transporter, ClC family [Propionibacterium acnes J165] gi|289158633|gb|EFD06837.1| chloride transporter, ClC family [Propionibacterium acnes J165] gi|313826878|gb|EFS64592.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL063PA1] gi|314979090|gb|EFT23184.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL072PA2] gi|315089636|gb|EFT61612.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL072PA1] gi|327334013|gb|EGE75728.1| chloride channel [Propionibacterium acnes HL096PA3] Length=575 Score = 324 bits (831), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 211/434 (49%), Positives = 290/434 (67%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+G ++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGVIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|315095202|gb|EFT67178.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL060PA1] gi|327328829|gb|EGE70589.1| chloride channel [Propionibacterium acnes HL103PA1] Length=575 Score = 323 bits (829), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 288/434 (67%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGAAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPLV GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLVVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLMI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF+ L P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYGGTTFFDHLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFASNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLKDR 465 >gi|314922017|gb|EFS85848.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL001PA1] Length=575 Score = 323 bits (828), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 288/434 (67%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGAAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPLV GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLVVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLMI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF+ L P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYGGTTFFDHLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFASNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLKDR 465 >gi|282854535|ref|ZP_06263871.1| chloride transporter, ClC family [Propionibacterium acnes J139] gi|282582396|gb|EFB87777.1| chloride transporter, ClC family [Propionibacterium acnes J139] gi|314980704|gb|EFT24798.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL110PA3] gi|315090977|gb|EFT62953.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL110PA4] Length=607 Score = 322 bits (826), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 288/434 (67%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGAAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPLV GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLVVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLMI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF+ L P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYGGTTFFDHLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFASNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLKDR 465 >gi|314965973|gb|EFT10072.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL082PA2] Length=575 Score = 322 bits (824), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 211/434 (49%), Positives = 287/434 (67%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGAAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPLV GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++ S+L I Sbjct 97 WAIPLVVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIITSSLMI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF+ L P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYGGTTFFDHLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFASNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T+ IY +Q +R Sbjct 454 DTS--IYTSQLKDR 465 >gi|257075702|ref|ZP_05570063.1| chloride channel protein [Ferroplasma acidarmanus fer1] Length=587 Score = 313 bits (801), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 191/461 (42%), Positives = 273/461 (60%), Gaps = 11/461 (2%) Query 35 GVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGH 94 + + S Y ++WF++G IGV+AG GA+ FY ++ ++ IP P+GEGG Sbjct 2 NLKLSSLPYFQRWFIVGAIIGVVAGFGALAFYFTIRLFEFIFFTHIVGMPIPHPLGEGGS 61 Query 95 RGSTGFA-RPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVL 153 +A R + IP+V G +++ I+ P + GHGTD AI S H + I+ R + Sbjct 62 LVYHFYALRYYLIPVVVAAGGLITGFIIYTFDPSSEGHGTDAAIRSFHYNHGKIKRRTPV 121 Query 154 VKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIF 213 VK +ASA+TIGSGGS GREGPTA I+AG S L L LS +D R AVA+GIGAGIG IF Sbjct 122 VKTIASAITIGSGGSAGREGPTALIAAGIGSFLADILGLSPKDRRIAVAVGIGAGIGTIF 181 Query 214 AAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKA 273 AP+GGA LGA I YR DF+ + P +AS Y++ + +GF+P+FG D F Sbjct 182 KAPIGGAVLGAEILYRRDFESEVIFPSLVASSIGYSIFASVVGFEPIFG--DYLNTF-NV 238 Query 274 WPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQIL 333 L ++ V+GL+A LY R F+ + ++ KP IGG +VG++ L P+IL Sbjct 239 LRLPFYAVLGLVAGLFSILYIRTFYGVRNLFKKFKIPNHFKPMIGGAIVGVIALLFPEIL 298 Query 334 SSGYGWAQLAA-----DRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 +GYGW +L + T L I+++LP KI+ATS ++ +GGSGG+F PGI IG Sbjct 299 GTGYGWVELLEYGKFNELVTFGLPILLILVLLPFIKIIATSFTVSSGGSGGVFAPGIFIG 358 Query 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 A +GA L + PG+ FV++ M++ FG+ +APLAV++MV EMTGS ++P Sbjct 359 ASLGALFGVLFHMIS-PGIVPVVAPFVIIGMLSFFGAAGKAPLAVILMVVEMTGSLQLLP 417 Query 449 GAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 GA++AV I A + S T +IYE+Q R+ + A G P Sbjct 418 GAMLAVSI-AYIASGTKYSIYESQVEQRRDSPANMGEYHTP 457 >gi|314985929|gb|EFT30021.1| chloride transporter, chloride channel family protein [Propionibacterium acnes HL005PA2] Length=575 Score = 311 bits (797), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 212/434 (49%), Positives = 291/434 (68%), Gaps = 6/434 (1%) Query 44 LRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARP 103 L +W L+G IG+++G+GA++F+ LK + +LL L Y P +GEGG T RP Sbjct 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query 104 WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTI 163 WAIPL+ GGA++S +V +AP A GHGTD AI +VH DP A++G+ VK++AS+L I Sbjct 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query 164 GSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALG 223 GSGGSGGREGPTAQISA S L ++L ++ D R AV+ +GIGAIF APLGGA LG Sbjct 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query 224 ASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIG 283 A + YRDD + ++P ++S A+ V G+ GF+P+FG + +F + L+WFV++G Sbjct 217 AGLLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query 284 LIAAAVGYLYARVFHASVAITRRLPGGP-VLKPAIGGLLVGLLGLPIPQILSSGYGWAQL 342 L A +G LY VF++ + RL P L PAIGGL VGLLGL IP L +GYG Q Sbjct 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query 343 AADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELT 402 L+ +PL +V+ +P AKIL+T+LSIG+GGSGG+FGPG+VIG GAA+WRL L Sbjct 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query 403 ELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLS 462 LPG+P P FV+V M+ACFG+V+ APL V++MV EMTG+ S++ +IAV +A ++ Sbjct 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query 463 RTNVTIYETQRLNR 476 T +IY +Q +R Sbjct 454 DT--SIYTSQLKDR 465 >gi|15899904|ref|NP_344509.1| hypothetical protein SSO3202 [Sulfolobus solfataricus P2] gi|13816637|gb|AAK43299.1| Conserved hypothetical protein [Sulfolobus solfataricus P2] Length=595 Score = 305 bits (780), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 196/470 (42%), Positives = 279/470 (60%), Gaps = 22/470 (4%) Query 34 FGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG 93 + +++ S Y KWF+LGI +GV+AGL A FYL L + L +L P P+GEGG Sbjct 12 YDMNLSSLPYFEKWFILGIVLGVVAGLAATTFYLLLHVFEDIFLFHLIGMSYPRPLGEGG 71 Query 94 ------HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAI 147 H G+ IP+ T G ++S LIV APEA GHGTD AI++ H + Sbjct 72 TLNFVFHPGNY-----LLIPISTAIGGLISGLIVYTFAPEAEGHGTDAAIKAYHYFQGKV 126 Query 148 RGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGA 207 + + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R AVA+GIGA Sbjct 127 KWVVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRAVAVGIGA 186 Query 208 GIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAE 267 GIG IF P+GGA L A I YR D + + P IAS Y + G+ GF P+FGY Sbjct 187 GIGTIFKTPIGGAILAAEILYRRDLEPEVIYPALIASAIGYTIFGSIFGFTPVFGYYTGT 246 Query 268 YRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGL 327 + L + V+GL++ V LY + F+ ++ ++L +KPAIGGL+ G++ L Sbjct 247 F---DPLRLPMYAVLGLVSGLVAILYPKTFYGINSLFKKLRITDHVKPAIGGLVTGVIAL 303 Query 328 PIPQILSSGYGWAQLAA-DRGTLLSIPLW----IVIVLPIAKILATSLSIGTGGSGGLFG 382 P+IL +GYGW L ++ L P+ ++++LP KI+ATS S+G+GGSGG+F Sbjct 304 LAPEILGTGYGWINLVEYEKFFALYSPVLPAIILIVILPFLKIIATSFSVGSGGSGGVFA 363 Query 383 PGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTG 442 PG+ IGA++GA+I + P V + FV++ MM+ F + PL+V+IMV EMT Sbjct 364 PGLFIGAYIGASIGLMFHYL-FPSVVPDIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTS 422 Query 443 SFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA 492 S ++PGA++AV I+ L+ N TIY +Q R+ + A + + P A Sbjct 423 SLQLLPGAMVAVAISYLV--SGNSTIYISQLPTRRDSPAHKAEYETPLMA 470 >gi|284175185|ref|ZP_06389154.1| hypothetical protein Ssol98_11135 [Sulfolobus solfataricus 98/2] gi|261601581|gb|ACX91184.1| Cl- channel voltage-gated family protein [Sulfolobus solfataricus 98/2] Length=582 Score = 303 bits (777), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 196/468 (42%), Positives = 278/468 (60%), Gaps = 22/468 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L +L P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIVLGVVAGLAATTFYLLLHVFEDIFLFHLIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S LIV APEA GHGTD AI++ H ++ Sbjct 61 NFVFHPGNY-----LLIPISTAIGGLISGLIVYTFAPEAEGHGTDAAIKAYHYFQGKVKW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R AVA+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRAVAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P IAS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALIASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ V LY + F+ ++ ++L +KPAIGGL+ G++ L Sbjct 235 --DPLRLPMYAVLGLVSGLVAILYPKTFYGINSLFKKLRITDHVKPAIGGLVTGVIALLA 292 Query 330 PQILSSGYGWAQLAA-DRGTLLSIPLW----IVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L ++ L P+ ++++LP KI+ATS S+G+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFALYSPVLPAIILIVILPFLKIIATSFSVGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA+I + P V + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASIGLMFHYL-FPSVVPDIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA 492 ++PGA++AV I+ L+ N TIY +Q R+ + A + + P A Sbjct 412 QLLPGAMVAVAISYLV--SGNSTIYISQLPTRRDSPAHKAEYETPLMA 457 >gi|238620607|ref|YP_002915433.1| Chloride channel core [Sulfolobus islandicus M.16.4] gi|238381677|gb|ACR42765.1| Chloride channel core [Sulfolobus islandicus M.16.4] Length=582 Score = 302 bits (773), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 197/465 (43%), Positives = 276/465 (60%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y +KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFKKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H IR Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|229585644|ref|YP_002844146.1| Chloride channel core [Sulfolobus islandicus M.16.27] gi|228020694|gb|ACP56101.1| Chloride channel core [Sulfolobus islandicus M.16.27] Length=582 Score = 301 bits (770), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 197/465 (43%), Positives = 275/465 (60%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H IR Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|229580056|ref|YP_002838456.1| Chloride channel core [Sulfolobus islandicus Y.G.57.14] gi|228010772|gb|ACP46534.1| Chloride channel core [Sulfolobus islandicus Y.G.57.14] Length=582 Score = 301 bits (770), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 197/465 (43%), Positives = 275/465 (60%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H +R Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA+I L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASIGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|323475488|gb|ADX86094.1| Chloride channel core [Sulfolobus islandicus REY15A] Length=582 Score = 300 bits (769), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 197/465 (43%), Positives = 275/465 (60%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GVIAGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVIAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H +R Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|323478210|gb|ADX83448.1| Chloride channel core [Sulfolobus islandicus HVE10/4] Length=582 Score = 300 bits (769), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 197/465 (43%), Positives = 275/465 (60%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GVIAGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVIAGLTATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H +R Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|284998669|ref|YP_003420437.1| Cl- channel, voltage-gated family protein [Sulfolobus islandicus L.D.8.5] gi|284446565|gb|ADB88067.1| Cl- channel, voltage-gated family protein [Sulfolobus islandicus L.D.8.5] Length=582 Score = 300 bits (768), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 196/465 (43%), Positives = 275/465 (60%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H +R Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|13540925|ref|NP_110613.1| chloride channel protein [Thermoplasma volcanium GSS1] gi|14324307|dbj|BAB59235.1| hypothetical protein [Thermoplasma volcanium GSS1] Length=592 Score = 300 bits (768), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 189/454 (42%), Positives = 279/454 (62%), Gaps = 14/454 (3%) Query 43 YLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFAR 102 Y KWF++G+ IGVI+GLGA+ FY A+K L ++ IP PVGEGG T + R Sbjct 15 YFEKWFIMGLIIGVISGLGALAFYFAIKLFEYLFLTHMVGATIPHPVGEGGSLAFTYYVR 74 Query 103 P-WAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASAL 161 + IP+ T G + S LIV APEA GHGTD AI + H + IR R +VK +ASA+ Sbjct 75 RFYLIPVSTALGGLFSGLIVYTFAPEAEGHGTDAAIRAFHNEQGKIRRRIPVVKTIASAI 134 Query 162 TIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAA 221 TIGSGGS GREGPTAQISAG SL+ LS+ D R AVA+GIG+GIG IF P+GG Sbjct 135 TIGSGGSAGREGPTAQISAGLGSLIADLFGLSDADRRIAVAVGIGSGIGTIFKTPIGGTM 194 Query 222 LGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVV 281 LGA I Y+ D + + + P +A+ Y++ + +GF+P+FGY A ++ + + +++V Sbjct 195 LGAEILYKRDLETQAIYPSLVANAVGYSIFASVVGFEPIFGYYTASFQVIR---IPYYMV 251 Query 282 IGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQ 341 +G+I+ Y + F+ +VA ++L KP IGG L G++ L P+I+++GYGW Sbjct 252 LGVISGLFAIFYVKSFYGTVAFFKKLKISNYYKPIIGGGLTGIIALFFPEIMATGYGWVN 311 Query 342 LAADRGTLLSIPLW------IVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAI 395 L ++ L IP + ++I+LP K++ATS ++G+GGSGG++ PGI IGA +G + Sbjct 312 LLMNQ-KLGEIPTFGIPLLLVLILLPFIKVIATSFTVGSGGSGGVYAPGIFIGAALGTVV 370 Query 396 WRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVG 455 +G P + FV++ M++ FGS + PL+V++MV EMTGS ++PGA+IA Sbjct 371 -AIGFHYLTPSIVPTITPFVIIGMISFFGSAGKVPLSVILMVVEMTGSLQLLPGAMIATF 429 Query 456 IAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 IA ++ + +IY Q R+ + A G + P Sbjct 430 IAYIISGK--YSIYHNQVDTRRDSPAHFGEYNTP 461 >gi|229581283|ref|YP_002839682.1| Chloride channel core [Sulfolobus islandicus Y.N.15.51] gi|228011999|gb|ACP47760.1| Chloride channel core [Sulfolobus islandicus Y.N.15.51] Length=582 Score = 298 bits (764), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 195/465 (42%), Positives = 274/465 (59%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H +R Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++G ++ L P + FV++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGTSVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|227828415|ref|YP_002830195.1| chloride channel core [Sulfolobus islandicus M.14.25] gi|227460211|gb|ACP38897.1| Chloride channel core [Sulfolobus islandicus M.14.25] Length=582 Score = 298 bits (764), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 196/465 (43%), Positives = 274/465 (59%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H IR Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPAIGGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + F ++ MM+ F + PL+V+IMV EMT S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFAIIGMMSFFAGAGKVPLSVLIMVTEMTSSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 >gi|227831171|ref|YP_002832951.1| Chloride channel core [Sulfolobus islandicus L.S.2.15] gi|227457619|gb|ACP36306.1| Chloride channel core [Sulfolobus islandicus L.S.2.15] Length=582 Score = 297 bits (760), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 194/465 (42%), Positives = 274/465 (59%), Gaps = 22/465 (4%) Query 36 VSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGG-- 93 +++ S Y KWF+LGI +GV+AGL A FYL L + L + P P+GEGG Sbjct 1 MNLSSLPYFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTL 60 Query 94 ----HRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRG 149 H G+ IP+ T G ++S +IV APEA GHGTD AI++ H +R Sbjct 61 NFIFHPGNY-----LLIPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRW 115 Query 150 RAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGI 209 + VK++ASA+TIGSGGS GREGPTAQ SAG S++ L+LS ED R A+A+GIGAGI Sbjct 116 VVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGI 175 Query 210 GAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYR 269 G IF P+GGA L A I YR D + + P +AS Y + G+ GF P+FGY + Sbjct 176 GTIFKTPIGGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF- 234 Query 270 FEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPI 329 L + V+GL++ + LY + F+ ++ ++L +KPA+GGL+ GL+ L Sbjct 235 --DPLRLPMYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAMGGLITGLIALLA 292 Query 330 PQILSSGYGWAQLAADRG--TLLS--IP-LWIVIVLPIAKILATSLSIGTGGSGGLFGPG 384 P+IL +GYGW L TL S IP + ++++LP KIL TS SIG+GGSGG+F PG Sbjct 293 PEILGTGYGWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPG 352 Query 385 IVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSF 444 + IGA++GA++ L P + FV++ MM+ F + PL+V+IMV EM S Sbjct 353 LFIGAYIGASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMASSL 411 Query 445 SVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRP 489 ++PGA+IAV I+ L+ N TIY +Q R+ + A + + P Sbjct 412 QLLPGAMIAVAISYLV--SGNNTIYISQLPTRRDSPAHKAEYETP 454 Lambda K H 0.322 0.141 0.430 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1053329043408 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40