BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0146

Length=310
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15839527|ref|NP_334564.1|  hypothetical protein MT0154 [Mycoba...   616    1e-174
gi|15607288|ref|NP_214660.1|  hypothetical protein Rv0146 [Mycoba...   616    1e-174
gi|183980388|ref|YP_001848679.1|  O-methyltransferase [Mycobacter...   484    5e-135
gi|15828427|ref|NP_302690.1|  hypothetical protein ML2640 [Mycoba...   484    5e-135
gi|221222991|sp|B2HLS5.2|Y357_MYCMM  RecName: Full=Putative S-ade...   484    7e-135
gi|118619821|ref|YP_908153.1|  O-methyltransferase [Mycobacterium...   483    2e-134
gi|240168151|ref|ZP_04746810.1|  O-methyltransferase [Mycobacteri...   471    4e-131
gi|296167339|ref|ZP_06849741.1|  methyltransferase [Mycobacterium...   468    6e-130
gi|254822359|ref|ZP_05227360.1|  methyltransferase, putative, fam...   467    1e-129
gi|41409662|ref|NP_962498.1|  hypothetical protein MAP3564 [Mycob...   460    1e-127
gi|342859420|ref|ZP_08716074.1|  methyltransferase, putative, fam...   458    5e-127
gi|254777491|ref|ZP_05219007.1|  methyltransferase, putative, fam...   458    5e-127
gi|333988734|ref|YP_004521348.1|  O-methyltransferase [Mycobacter...   409    4e-112
gi|118467600|ref|YP_884510.1|  methyltransferase [Mycobacterium s...   390    1e-106
gi|296165661|ref|ZP_06848181.1|  methyltransferase [Mycobacterium...   389    3e-106
gi|167970262|ref|ZP_02552539.1|  hypothetical protein MtubH3_2044...   370    1e-100
gi|126432691|ref|YP_001068382.1|  putative methyltransferase [Myc...   366    2e-99 
gi|108797069|ref|YP_637266.1|  hypothetical protein Mmcs_0088 [My...   364    1e-98 
gi|145221338|ref|YP_001132016.1|  putative methyltransferase [Myc...   337    1e-90 
gi|315441778|ref|YP_004074657.1|  methyltransferase, , TIGR00027 ...   333    2e-89 
gi|120401132|ref|YP_950961.1|  putative methyltransferase [Mycoba...   313    2e-83 
gi|169631681|ref|YP_001705330.1|  hypothetical protein MAB_4607c ...   279    3e-73 
gi|342859421|ref|ZP_08716075.1|  hypothetical protein MCOL_11093 ...   278    9e-73 
gi|254822360|ref|ZP_05227361.1|  methyltransferase, putative, fam...   273    3e-71 
gi|169631680|ref|YP_001705329.1|  hypothetical protein MAB_4606c ...   265    9e-69 
gi|118464245|ref|YP_883578.1|  methyltransferase, putative, famil...   263    3e-68 
gi|254776879|ref|ZP_05218395.1|  methyltransferase, putative, fam...   261    8e-68 
gi|41410287|ref|NP_963123.1|  hypothetical protein MAP4189c [Myco...   261    1e-67 
gi|118466498|ref|YP_884267.1|  methyltransferase, putative, famil...   261    1e-67 
gi|336459900|gb|EGO38812.1|  methyltransferase, putative, TIGR000...   258    7e-67 
gi|41409661|ref|NP_962497.1|  hypothetical protein MAP3563 [Mycob...   258    7e-67 
gi|342861820|ref|ZP_08718465.1|  methyltransferase, putative, fam...   256    3e-66 
gi|183980389|ref|YP_001848680.1|  O-methyltransferase [Mycobacter...   253    2e-65 
gi|221222987|sp|A0PWG2.2|Y4761_MYCUA  RecName: Full=Putative S-ad...   253    3e-65 
gi|221222875|sp|A0QNM1.2|Y093_MYCS2  RecName: Full=Putative S-ade...   252    6e-65 
gi|254818385|ref|ZP_05223386.1|  methyltransferase, putative, fam...   251    7e-65 
gi|118468041|ref|YP_884509.1|  methyltransferase [Mycobacterium s...   251    8e-65 
gi|118619535|ref|YP_907867.1|  O-methyltransferase [Mycobacterium...   251    1e-64 
gi|183985291|ref|YP_001853582.1|  O-methyltransferase [Mycobacter...   250    3e-64 
gi|15610903|ref|NP_218284.1|  hypothetical protein Rv3767c [Mycob...   249    3e-64 
gi|221222872|sp|A1KEW5.2|Y181_MYCBP  RecName: Full=Putative S-ade...   247    1e-63 
gi|15607287|ref|NP_214659.1|  hypothetical protein Rv0145 [Mycoba...   247    2e-63 
gi|340625180|ref|YP_004743632.1|  hypothetical protein MCAN_01481...   246    2e-63 
gi|339630227|ref|YP_004721869.1|  hypothetical protein MAF_01450 ...   246    4e-63 
gi|183980387|ref|YP_001848678.1|  hypothetical protein MMAR_0356 ...   244    1e-62 
gi|240168533|ref|ZP_04747192.1|  O-methyltransferase [Mycobacteri...   244    1e-62 
gi|254819983|ref|ZP_05224984.1|  methyltransferase [Mycobacterium...   243    2e-62 
gi|118466717|ref|YP_881767.1|  methyltransferase [Mycobacterium a...   243    2e-62 
gi|183980567|ref|YP_001848858.1|  O-methyltransferase [Mycobacter...   241    8e-62 
gi|340628737|ref|YP_004747189.1|  hypothetical protein MCAN_37871...   241    9e-62 


>gi|15839527|ref|NP_334564.1| hypothetical protein MT0154 [Mycobacterium tuberculosis CDC1551]
 gi|253797066|ref|YP_003030067.1| hypothetical protein TBMG_00147 [Mycobacterium tuberculosis KZN 
1435]
 gi|254233537|ref|ZP_04926863.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
 25 more sequence titles
 Length=313

 Score =  616 bits (1589),  Expect = 1e-174, Method: Compositional matrix adjust.
 Identities = 310/310 (100%), Positives = 310/310 (100%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP
Sbjct  4    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
            TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL
Sbjct  64   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR
Sbjct  124  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV
Sbjct  184  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA
Sbjct  244  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  303

Query  301  FAEFVTAERL  310
            FAEFVTAERL
Sbjct  304  FAEFVTAERL  313


>gi|15607288|ref|NP_214660.1| hypothetical protein Rv0146 [Mycobacterium tuberculosis H37Rv]
 gi|31791324|ref|NP_853817.1| hypothetical protein Mb0151 [Mycobacterium bovis AF2122/97]
 gi|121636058|ref|YP_976281.1| hypothetical protein BCG_0182 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 55 more sequence titles
 Length=310

 Score =  616 bits (1589),  Expect = 1e-174, Method: Compositional matrix adjust.
 Identities = 310/310 (100%), Positives = 310/310 (100%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP
Sbjct  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
            TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL
Sbjct  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR
Sbjct  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV
Sbjct  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA
Sbjct  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300

Query  301  FAEFVTAERL  310
            FAEFVTAERL
Sbjct  301  FAEFVTAERL  310


>gi|183980388|ref|YP_001848679.1| O-methyltransferase [Mycobacterium marinum M]
 gi|183173714|gb|ACC38824.1| O-Methyltransferase [Mycobacterium marinum M]
Length=313

 Score =  484 bits (1247),  Expect = 5e-135, Method: Compositional matrix adjust.
 Identities = 249/310 (81%), Positives = 273/310 (89%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDI+TSVGATAVMVAAARAVET +P+PLIRDPYAR+LVTNA AG IWEAMLD 
Sbjct  4    MRTHDDTWDIRTSVGATAVMVAAARAVETSKPEPLIRDPYARMLVTNANAGVIWEAMLDQ  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  AIDAETAA V ++RSYQAVRTNFFDTYFA AVAAGIRQVVILASGLDSRAYRL
Sbjct  64   EMVAKVEAIDAETAATVEHMRSYQAVRTNFFDTYFADAVAAGIRQVVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL+YKS TLAENGVTP+A RREV  DLRQDWP+ALR AGFDP+AR
Sbjct  124  DWPAGTTVYEIDQPQVLAYKSATLAENGVTPAAERREVAIDLRQDWPSALRAAGFDPSAR  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLFTQ+G +S AGSRIAAETA  H +ERR +MR RF+KVA  
Sbjct  184  TAWLAEGLLMYLPAEAQDRLFTQIGELSCAGSRIAAETAGNHADERREQMRERFRKVAQT  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+EQTIDV EL+YHD DRA +  WL +HGWRA +Q A DEM RVGRWVEGVPMADD  A
Sbjct  244  LGLEQTIDVHELIYHDPDRALLGQWLNEHGWRANAQNACDEMHRVGRWVEGVPMADDKQA  303

Query  301  FAEFVTAERL  310
            ++EFVTAERL
Sbjct  304  YSEFVTAERL  313


>gi|15828427|ref|NP_302690.1| hypothetical protein ML2640 [Mycobacterium leprae TN]
 gi|221230904|ref|YP_002504320.1| hypothetical protein MLBr_02640 [Mycobacterium leprae Br4923]
 gi|81537205|sp|Q9CCZ4.1|Y2640_MYCLE RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
ML2640
 6 more sequence titles
 Length=310

 Score =  484 bits (1247),  Expect = 5e-135, Method: Compositional matrix adjust.
 Identities = 242/310 (79%), Positives = 271/310 (88%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDIKTSVG TAVMVAAARA ETDRPD LIRDPYA+LLVTN GAGA+WEAMLDP
Sbjct  1    MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAMLDP  60

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
            ++VAK  AIDAE AA+V ++RSYQAVRTNFFDTYF +AV  GIRQ VILASGLDSRAYRL
Sbjct  61   SMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRL  120

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWP GT VYEIDQPKVL+YKSTTLAE+GVTP+A RREVP DLRQDWP ALR AGFDP+AR
Sbjct  121  DWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSAR  180

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA AQD LFT++G +S  GSRIA ET+P+HG+E R +M+ RF++V+D 
Sbjct  181  TAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA  240

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG EQ +DVQEL+YHD++RA VADWL  HGWRA +Q APDEMRRVGRW +GVPMADD  A
Sbjct  241  LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDA  300

Query  301  FAEFVTAERL  310
            FAEFVTA RL
Sbjct  301  FAEFVTAHRL  310


>gi|221222991|sp|B2HLS5.2|Y357_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_0357
Length=310

 Score =  484 bits (1246),  Expect = 7e-135, Method: Compositional matrix adjust.
 Identities = 249/310 (81%), Positives = 273/310 (89%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDI+TSVGATAVMVAAARAVET +P+PLIRDPYAR+LVTNA AG IWEAMLD 
Sbjct  1    MRTHDDTWDIRTSVGATAVMVAAARAVETSKPEPLIRDPYARMLVTNANAGVIWEAMLDQ  60

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  AIDAETAA V ++RSYQAVRTNFFDTYFA AVAAGIRQVVILASGLDSRAYRL
Sbjct  61   EMVAKVEAIDAETAATVEHMRSYQAVRTNFFDTYFADAVAAGIRQVVILASGLDSRAYRL  120

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL+YKS TLAENGVTP+A RREV  DLRQDWP+ALR AGFDP+AR
Sbjct  121  DWPAGTTVYEIDQPQVLAYKSATLAENGVTPAAERREVAIDLRQDWPSALRAAGFDPSAR  180

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLFTQ+G +S AGSRIAAETA  H +ERR +MR RF+KVA  
Sbjct  181  TAWLAEGLLMYLPAEAQDRLFTQIGELSCAGSRIAAETAGNHADERREQMRERFRKVAQT  240

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+EQTIDV EL+YHD DRA +  WL +HGWRA +Q A DEM RVGRWVEGVPMADD  A
Sbjct  241  LGLEQTIDVHELIYHDPDRALLGQWLNEHGWRANAQNACDEMHRVGRWVEGVPMADDKQA  300

Query  301  FAEFVTAERL  310
            ++EFVTAERL
Sbjct  301  YSEFVTAERL  310


>gi|118619821|ref|YP_908153.1| O-methyltransferase [Mycobacterium ulcerans Agy99]
 gi|221222979|sp|A0PWG3.1|Y4762_MYCUA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MUL_4762
 gi|118571931|gb|ABL06682.1| O-Methyltransferase [Mycobacterium ulcerans Agy99]
Length=310

 Score =  483 bits (1243),  Expect = 2e-134, Method: Compositional matrix adjust.
 Identities = 248/310 (80%), Positives = 273/310 (89%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDI+TSVGATAVMVAAARAVET +P+PLIRDPYAR+LVTNA AG IWEAMLD 
Sbjct  1    MRTHDDTWDIRTSVGATAVMVAAARAVETSKPEPLIRDPYARMLVTNANAGVIWEAMLDQ  60

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  AIDAETAA V ++RSYQAVRTNFFDTYFA AVAAGIRQVVILASGLDSRAYRL
Sbjct  61   EMVAKVEAIDAETAATVEHMRSYQAVRTNFFDTYFADAVAAGIRQVVILASGLDSRAYRL  120

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL+YKS TLAENGVTP+A RREV  DLRQDWP+ALR AGFDP+AR
Sbjct  121  DWPAGTTVYEIDQPQVLAYKSATLAENGVTPAAERREVAIDLRQDWPSALRAAGFDPSAR  180

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLFTQ+G +S AGSRIAAETA  H +ERR +MR RF+KVA  
Sbjct  181  TAWLAEGLLMYLPAEAQDRLFTQIGELSCAGSRIAAETAGNHADERREQMRERFRKVAQT  240

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+EQTIDV EL+YHD DRA +  WL +HGWRA +Q A DEM RVGRWVEGVPMADD  A
Sbjct  241  LGLEQTIDVHELIYHDPDRAPLGQWLNEHGWRANAQNACDEMHRVGRWVEGVPMADDKQA  300

Query  301  FAEFVTAERL  310
            +++FVTAERL
Sbjct  301  YSDFVTAERL  310


>gi|240168151|ref|ZP_04746810.1| O-methyltransferase [Mycobacterium kansasii ATCC 12478]
Length=313

 Score =  471 bits (1213),  Expect = 4e-131, Method: Compositional matrix adjust.
 Identities = 246/310 (80%), Positives = 273/310 (89%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDI+TSVGATAVMVAAARAVET++P PLIRDPYA+LLVTNA AG +WEAMLD 
Sbjct  4    LRTHDDTWDIRTSVGATAVMVAAARAVETEQPAPLIRDPYAKLLVTNANAGVLWEAMLDE  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  A+DAETAA V ++RSYQAVRTNFFDTYFA AVA GIRQVVILASGLDSRAYRL
Sbjct  64   QMVAKMQALDAETAATVQHMRSYQAVRTNFFDTYFADAVADGIRQVVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL+YKS TLA NGVTPSA RREVP DLR DWPAALR AGFDPTAR
Sbjct  124  DWPAGTTVYEIDQPQVLAYKSATLAGNGVTPSADRREVPIDLRLDWPAALRAAGFDPTAR  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+G +S  GSRIAAETA  H +ERR +MR RFKKVA+ 
Sbjct  184  TAWLAEGLLMYLPADAQDRLFIQIGELSPPGSRIAAETAGNHADERREQMRERFKKVAET  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+E+T+DVQEL+YHD DRA VA WL +HGWRA ++ A DEMRRVGRWVEGVPMADD  A
Sbjct  244  LGLEETVDVQELIYHDPDRAKVAGWLNEHGWRATARNAGDEMRRVGRWVEGVPMADDKDA  303

Query  301  FAEFVTAERL  310
            F+EFVTA+RL
Sbjct  304  FSEFVTADRL  313


>gi|296167339|ref|ZP_06849741.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897283|gb|EFG76887.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=313

 Score =  468 bits (1204),  Expect = 6e-130, Method: Compositional matrix adjust.
 Identities = 224/310 (73%), Positives = 265/310 (86%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDIKTSVG+TAVMVAAARA+ET++PDPLIRDPYARLLV NAGA  +WEAMLDP
Sbjct  4    LRTHDDTWDIKTSVGSTAVMVAAARAIETEQPDPLIRDPYARLLVNNAGAAVLWEAMLDP  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  AID E+AA + ++R YQAVRT+FFD+YFA AV AGIRQVVILASGLDSRAYRL
Sbjct  64   EVVAKIEAIDEESAARIQHMRGYQAVRTHFFDSYFADAVGAGIRQVVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT+VYEIDQP+V+ YKS TLA++G TPSA RREV  DLR+DWPAALR AGFDPT  
Sbjct  124  DWPAGTVVYEIDQPQVMDYKSATLADSGATPSADRREVAIDLREDWPAALRAAGFDPTKP  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQD+LFTQ+G +S AGSR++AETAP+H EERR +MR RFKKVAD 
Sbjct  184  TAWLAEGLLMYLPAEAQDKLFTQIGELSPAGSRVSAETAPMHAEERRQKMRERFKKVADE  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+E+T+DV EL+Y D+ RA + +WL +HGWRA +Q + DEM R+ R V+ V + DD  A
Sbjct  244  LGLEETVDVGELMYRDEHRADLTEWLNEHGWRATAQNSIDEMHRLNRRVQSVELDDDKDA  303

Query  301  FAEFVTAERL  310
            F++FV AERL
Sbjct  304  FSDFVIAERL  313


>gi|254822359|ref|ZP_05227360.1| methyltransferase, putative, family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=313

 Score =  467 bits (1201),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 227/310 (74%), Positives = 263/310 (85%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDIK+SVG TAVMVAAARA+ET++PD LIRDPYARLLV NAGA  +WEAMLDP
Sbjct  4    LRTHDDTWDIKSSVGTTAVMVAAARAIETEQPDALIRDPYARLLVNNAGADVLWEAMLDP  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  AID E+AA + ++R YQAVRT+FFD YFA AVA GIRQVVILASGLDSRAYRL
Sbjct  64   DVVAKIEAIDEESAARIQHMRGYQAVRTHFFDEYFADAVATGIRQVVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL YK+TTLAE+GVTPSA RREV  DLR+DWPAALR AGFDPT  
Sbjct  124  DWPAGTTVYEIDQPQVLDYKTTTLAESGVTPSADRREVAIDLREDWPAALRAAGFDPTRP  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQD+LFTQ+G +S AGSR++AETAP+H EERR +MR RFKKVAD 
Sbjct  184  TAWLAEGLLMYLPAEAQDKLFTQIGELSPAGSRVSAETAPMHAEERRQQMRERFKKVADQ  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+E+TIDV EL+Y D+ RA++ADWL DHGWRA +Q + DEM R+ R V+   +  D  A
Sbjct  244  LGLEETIDVGELMYRDEHRANLADWLNDHGWRATAQNSIDEMHRLNRGVQSFELDQDKDA  303

Query  301  FAEFVTAERL  310
            F++FV AERL
Sbjct  304  FSDFVIAERL  313


>gi|41409662|ref|NP_962498.1| hypothetical protein MAP3564 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118465946|ref|YP_884266.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|81413322|sp|Q73U04.1|Y3564_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_3564
 gi|221222973|sp|A0QMX8.1|Y5149_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_5149
 gi|41398494|gb|AAS06114.1| hypothetical protein MAP_3564 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118167233|gb|ABK68130.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|336459899|gb|EGO38811.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=313

 Score =  460 bits (1184),  Expect = 1e-127, Method: Compositional matrix adjust.
 Identities = 231/309 (75%), Positives = 266/309 (87%), Gaps = 0/309 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDIK+SVG TAVMVAAARAVET++PDPLIRDPYA+LLVTN+GAG +WEAMLDP
Sbjct  4    LRTHDDTWDIKSSVGTTAVMVAAARAVETEQPDPLIRDPYAKLLVTNSGAGVLWEAMLDP  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             + A+  A+D E+AA + ++R YQAVRT+FFDTYFA AVAAGIRQ+VILASGLDSRAYRL
Sbjct  64   DIAARVEALDEESAAHLHHMRGYQAVRTHFFDTYFADAVAAGIRQIVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL+YKSTTLAENGVTPSA RREV  DLRQDWPAALR AGFDPT R
Sbjct  124  DWPAGTTVYEIDQPQVLAYKSTTLAENGVTPSADRREVAVDLRQDWPAALRAAGFDPTQR  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLFT +G +S AGSR+AAETAP H +ERR +MR RFKKVAD 
Sbjct  184  TAWLAEGLLMYLPAEAQDRLFTLIGELSPAGSRVAAETAPNHADERRQQMRERFKKVADE  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            +G EQT+DV EL+Y D  RA V +WL  HGWRA ++ +   MRR+GRW+E VP+ADD  A
Sbjct  244  IGFEQTVDVGELMYRDDHRADVTEWLNAHGWRATAEHSTAAMRRLGRWIENVPLADDKDA  303

Query  301  FAEFVTAER  309
            F++FV AER
Sbjct  304  FSDFVVAER  312


>gi|342859420|ref|ZP_08716074.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342133661|gb|EGT86864.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=313

 Score =  458 bits (1179),  Expect = 5e-127, Method: Compositional matrix adjust.
 Identities = 222/310 (72%), Positives = 263/310 (85%), Gaps = 0/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDIK+SVG TAVMVAAARA+ET++PD LIRDPYARLLV NAGA  +WEAMLDP
Sbjct  4    LRTHDDTWDIKSSVGTTAVMVAAARAIETEQPDALIRDPYARLLVNNAGAEVLWEAMLDP  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +VAK  AID E+AA + ++R YQAVRT+FFD+YFA AVAAGIRQVVILASGLDSRAYRL
Sbjct  64   EVVAKIEAIDEESAARMQHMRGYQAVRTHFFDSYFADAVAAGIRQVVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL YK+TTLAE+G  PSA RREV  DLR+DWP+ALR AGFDP   
Sbjct  124  DWPAGTTVYEIDQPQVLDYKTTTLAESGAKPSADRREVAIDLREDWPSALRAAGFDPAQP  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQD+LFTQ+G +S AGSR++AETAP+H EERR +MR RFKKVA  
Sbjct  184  TAWLAEGLLMYLPAEAQDKLFTQIGELSPAGSRVSAETAPMHAEERRQQMRERFKKVAAE  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            LG+E+T+DV EL+Y D+ RA++ADWL DHGWRA +Q + DEM R+GR V+   + +D  A
Sbjct  244  LGLEETVDVGELMYRDEHRANLADWLNDHGWRATAQNSIDEMHRLGRGVQSSEVDEDRDA  303

Query  301  FAEFVTAERL  310
            F++FV A+RL
Sbjct  304  FSDFVVAKRL  313


>gi|254777491|ref|ZP_05219007.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=313

 Score =  458 bits (1178),  Expect = 5e-127, Method: Compositional matrix adjust.
 Identities = 230/309 (75%), Positives = 266/309 (87%), Gaps = 0/309 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDIK+SVG TAVMVAAARAVET++PDPLIRDPYA+LLVTN+GAG +WEAMLDP
Sbjct  4    LRTHDDTWDIKSSVGTTAVMVAAARAVETEQPDPLIRDPYAKLLVTNSGAGVLWEAMLDP  63

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             + A+  A+D E+AA + ++R YQAVRT+FFDTYFA AVAAGIRQ+VILASGLDSRAYRL
Sbjct  64   DIAARVEALDEESAAHLHHMRGYQAVRTHFFDTYFADAVAAGIRQIVILASGLDSRAYRL  123

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQP+VL+YKSTTLAENGVTPSA RREV  DLRQDWPAALR AGFDPT R
Sbjct  124  DWPAGTTVYEIDQPQVLAYKSTTLAENGVTPSADRREVAVDLRQDWPAALRAAGFDPTQR  183

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL+YLPAEAQDRLFT +G +S AGSR+AAETAP H +ERR +MR RFKKVAD 
Sbjct  184  TAWLAEGLLVYLPAEAQDRLFTLIGELSPAGSRVAAETAPNHADERRQQMRERFKKVADE  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            +G EQT+DV EL+Y D  RA V +WL  HGWRA ++ +   MRR+GRW+E VP+ADD  A
Sbjct  244  IGFEQTVDVGELMYRDDHRADVTEWLNAHGWRATAEHSTAAMRRLGRWIENVPLADDKDA  303

Query  301  FAEFVTAER  309
            F++FV AER
Sbjct  304  FSDFVVAER  312


>gi|333988734|ref|YP_004521348.1| O-methyltransferase [Mycobacterium sp. JDM601]
 gi|333484702|gb|AEF34094.1| O-methyltransferase [Mycobacterium sp. JDM601]
Length=311

 Score =  409 bits (1050),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 212/309 (69%), Positives = 246/309 (80%), Gaps = 2/309 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RTHDDTWDI TSVG+TAVMVAAARAVETD  DPLI DPYA+LLV NAG G +WE +L+ 
Sbjct  4    LRTHDDTWDIATSVGSTAVMVAAARAVETDSSDPLISDPYAKLLVANAGTG-VWETLLNE  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
            +L+ K  ++D E AA+  ++RSYQAVRT+FFD YFA AV AGIRQVVILASGLDSRAYRL
Sbjct  63   SLIDKLESVDPEIAAVYHHMRSYQAVRTHFFDAYFAEAVGAGIRQVVILASGLDSRAYRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPA T VYEIDQPKVL YK TTLA + V      R V  DLRQDWPAAL  AGFDP A 
Sbjct  123  DWPAATTVYEIDQPKVLGYKETTLAAHDVRAPVQHRAVAIDLRQDWPAALTAAGFDPAAP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+ A+S  GSRIA ETA  H ++RR EM  RFKKVA+ 
Sbjct  183  TAWLAEGLLMYLPADAQDRLFEQITALSAPGSRIAVETAANHADQRRQEMSERFKKVAEQ  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
            +G+EQT+D+Q+L+YHD+DRA+V +WL  HGWRA +Q +  EMRR+GRWV  VPM DD  A
Sbjct  243  IGLEQTVDIQDLIYHDEDRAAVPEWLNGHGWRATAQHSTAEMRRLGRWV-NVPMGDDTDA  301

Query  301  FAEFVTAER  309
            F+EFVTA R
Sbjct  302  FSEFVTAVR  310


>gi|118467600|ref|YP_884510.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
 gi|221222834|sp|A0QNM2.1|Y095_MYCS2 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MSMEG_0095
 gi|118168887|gb|ABK69783.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
Length=311

 Score =  390 bits (1002),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 206/312 (67%), Positives = 233/312 (75%), Gaps = 6/312 (1%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT DDTWDI TSVG+TAVMVAAARA ET+R D LIRDPYA++LV  AG G +WE +LD 
Sbjct  4    LRTDDDTWDIATSVGSTAVMVAAARAGETERDDALIRDPYAKILVAGAGTG-VWETVLDS  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
               AK   +D E AAI A++ +YQAVRT+FFD Y+  A  AGIRQ+VILASGLDSRAYRL
Sbjct  63   EFAAKIENLDPEAAAIFAHMGNYQAVRTHFFDAYYREAADAGIRQIVILASGLDSRAYRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT VYEIDQPKVL YKS TL E+G+ P A RREVP DLR DWP AL DAGFD +  
Sbjct  123  DWPAGTTVYEIDQPKVLEYKSATLREHGIEPVAQRREVPVDLRFDWPTALHDAGFDASLP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPAEAQDRLF  V  +S  GSRIA ETA V   +RR  MR RFKK AD 
Sbjct  183  TAWLAEGLLMYLPAEAQDRLFELVTELSAPGSRIAVETAGVAATDRREAMRERFKKFADQ  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDP--  298
            L +   +D+QELVY D DRA VA+WL  HGWRAR   A DEMRR+ R VE   + DDP  
Sbjct  243  LNLSSALDIQELVYDDPDRADVAEWLDAHGWRARGVHALDEMRRLDRLVE---LPDDPDR  299

Query  299  TAFAEFVTAERL  310
             AF+ FVTA+RL
Sbjct  300  AAFSTFVTAQRL  311


>gi|296165661|ref|ZP_06848181.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295898978|gb|EFG78464.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=312

 Score =  389 bits (1000),  Expect = 3e-106, Method: Compositional matrix adjust.
 Identities = 212/310 (69%), Positives = 242/310 (79%), Gaps = 3/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEA-MLD  59
            +RT DDTWDI TSVGATAVMVAAARA+ET+RPDPLIRDPYARLL ++AG G +WE  +LD
Sbjct  4    LRTGDDTWDIATSVGATAVMVAAARAIETERPDPLIRDPYARLLASHAGTG-VWETILLD  62

Query  60   PTLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYR  119
             +LV K AAIDA+TAA++ ++R YQAVRT+FFD YF  A  AGIRQVVILASGLDSRAYR
Sbjct  63   DSLVDKVAAIDAQTAAVLEHMRGYQAVRTHFFDAYFTHATQAGIRQVVILASGLDSRAYR  122

Query  120  LDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTA  179
            LDWPAGT VYEIDQPKVL+YKS TLAENGV PSA RREV  DLR+DWPAAL   GFD T 
Sbjct  123  LDWPAGTTVYEIDQPKVLAYKSRTLAENGVAPSATRREVAIDLRRDWPAALCATGFDTTV  182

Query  180  RTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVAD  239
             TAWLAEGLLMYLPA+AQD+LF  V  +S  GSRIAAETA    +  R E R RF++VA 
Sbjct  183  PTAWLAEGLLMYLPADAQDQLFAHVTLLSAPGSRIAAETAARINDAWRRESRERFERVAT  242

Query  240  VLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPT  299
             L +E T  + +L+YHD DRA VADWL  HGWRA +  + DEMRR GRWV+ V   +D  
Sbjct  243  QLSLELTFYLDDLIYHDDDRAVVADWLNLHGWRATAHNSADEMRRRGRWVD-VAAGEDWD  301

Query  300  AFAEFVTAER  309
            A A FVTAER
Sbjct  302  AVAHFVTAER  311


>gi|167970262|ref|ZP_02552539.1| hypothetical protein MtubH3_20448 [Mycobacterium tuberculosis 
H37Ra]
Length=334

 Score =  370 bits (951),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 213/215 (99%), Positives = 213/215 (99%), Gaps = 2/215 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP
Sbjct  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
            TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL
Sbjct  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR
Sbjct  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSV--AGSR  213
            TAWLAEGLLMYLPAEAQDRLFTQVGAVSV  AGSR
Sbjct  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVRAAGSR  215


>gi|126432691|ref|YP_001068382.1| putative methyltransferase [Mycobacterium sp. JLS]
 gi|221222854|sp|A3PSL4.1|Y078_MYCSJ RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mjls_0078
 gi|126232491|gb|ABN95891.1| putative methyltransferase [Mycobacterium sp. JLS]
Length=312

 Score =  366 bits (940),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 201/310 (65%), Positives = 239/310 (78%), Gaps = 2/310 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT DDTWDI TSVG+TAVMVAA+RA ET+R + LIRDPYARLLVT AG G IWE++LD 
Sbjct  4    LRTADDTWDIATSVGSTAVMVAASRAAETERDEALIRDPYARLLVTGAGTG-IWESVLDA  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
              V   AA DAE AAI  ++ SYQAVRT+FFD +F +A  AGIRQ+VILASGLDSRAYRL
Sbjct  63   KFVETVAAADAEAAAIFEHMNSYQAVRTHFFDAFFTAAAEAGIRQIVILASGLDSRAYRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWP+GT VYEIDQPKVL YKS TLAE+GV P A RREV  DLR DWPAALR AGFDP+  
Sbjct  123  DWPSGTTVYEIDQPKVLEYKSATLAEHGVEPVATRREVGIDLRHDWPAALRGAGFDPSRP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+  +S  GSR+AAETA V  E+RR +MR RF+++A+ 
Sbjct  183  TAWLAEGLLMYLPADAQDRLFEQITELSAPGSRVAAETAGVQAEDRRQQMRERFERIAEK  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
              +  ++D+Q+L+Y D DRA VADWL  HGW A +  +  EMRR+ RW     + DD  A
Sbjct  243  FDMTASLDIQQLIYEDPDRADVADWLDAHGWTATAVSSQQEMRRLDRWALPADLTDD-DA  301

Query  301  FAEFVTAERL  310
            F+ FVTAE+L
Sbjct  302  FSNFVTAEKL  311


>gi|108797069|ref|YP_637266.1| hypothetical protein Mmcs_0088 [Mycobacterium sp. MCS]
 gi|119866154|ref|YP_936106.1| putative methyltransferase [Mycobacterium sp. KMS]
 gi|123179785|sp|Q1BFX4.1|Y088_MYCSS RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mmcs_0088
 gi|221222835|sp|A1U908.1|Y097_MYCSK RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mkms_0097
 gi|108767488|gb|ABG06210.1| Protein of unknown function Mtu_121 [Mycobacterium sp. MCS]
 gi|119692243|gb|ABL89316.1| putative methyltransferase [Mycobacterium sp. KMS]
Length=312

 Score =  364 bits (934),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 200/309 (65%), Positives = 239/309 (78%), Gaps = 2/309 (0%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT DDTWDI TSVG+TAVMVAA+RA ET+R + LIRDPYARLLVT AG G IWE++LD 
Sbjct  4    LRTADDTWDIATSVGSTAVMVAASRAAETERDEALIRDPYARLLVTGAGTG-IWESVLDA  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
              V   AA DAE AAI  ++ SYQAVRT+FFD +F +A  AGIRQ+VILASGLDSRAYRL
Sbjct  63   KFVETVAAADAEAAAIFEHMISYQAVRTHFFDAFFTAAAEAGIRQIVILASGLDSRAYRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWP+GT VYEIDQPKVL YKS TLAE+GV P+A RREV  DLR DWPAALR AGFDP+  
Sbjct  123  DWPSGTTVYEIDQPKVLEYKSATLAEHGVEPAATRREVGIDLRHDWPAALRGAGFDPSRP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+  +S  GSR+AAETA V  E+RR +MR RF+++A+ 
Sbjct  183  TAWLAEGLLMYLPADAQDRLFEQITELSAPGSRVAAETAGVQAEDRRQQMRERFERIAEK  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDPTA  300
              +  ++D+Q+L+Y D DRA VADWL  HGW A +  +  EMRR+ RW     + DD  A
Sbjct  243  FDMTASLDIQQLIYEDPDRADVADWLDAHGWTATAVSSQQEMRRLDRWALPADLTDD-DA  301

Query  301  FAEFVTAER  309
            F+ FVTAE+
Sbjct  302  FSNFVTAEK  310


>gi|145221338|ref|YP_001132016.1| putative methyltransferase [Mycobacterium gilvum PYR-GCK]
 gi|221222945|sp|A4T523.1|Y743_MYCGI RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mflv_0743
 gi|145213824|gb|ABP43228.1| putative methyltransferase [Mycobacterium gilvum PYR-GCK]
Length=309

 Score =  337 bits (864),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 189/311 (61%), Positives = 233/311 (75%), Gaps = 6/311 (1%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT DDTWDI +SVGATAVMVAAARA ET+R D LI DPYA++LV  AGAGA W  + D 
Sbjct  4    LRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEGAGAGA-WRFIADE  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             LVAKA+  D E  A+  ++++YQAVRT+FFD +F++AV AG+RQ+VILASGLDSRA+RL
Sbjct  63   DLVAKASESDTEVGALFEHMKNYQAVRTHFFDAFFSAAVDAGVRQIVILASGLDSRAFRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
             WPAGT+VYEIDQP VL YKS+TLA +GV P+A RREVP DLRQDWPAAL   GFDP   
Sbjct  123  PWPAGTVVYEIDQPLVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+  +S  GS++AAE+  VH  +RR  MR RF  +A  
Sbjct  183  TAWLAEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPDRRERMRERFASIASQ  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMAD-DPT  299
            + IE  +D+ EL Y D DRA VA+WL  HGW A++  + D MRR+ R+VE   +AD D  
Sbjct  243  IDIE-PMDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYVE---VADSDGQ  298

Query  300  AFAEFVTAERL  310
            +F+ F T  +L
Sbjct  299  SFSTFTTGTKL  309


>gi|315441778|ref|YP_004074657.1| methyltransferase, , TIGR00027 family [Mycobacterium sp. Spyr1]
 gi|315260081|gb|ADT96822.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
sp. Spyr1]
Length=309

 Score =  333 bits (854),  Expect = 2e-89, Method: Compositional matrix adjust.
 Identities = 187/311 (61%), Positives = 231/311 (75%), Gaps = 6/311 (1%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT DDTWDI +SVGATAVMVAAARA ET+R D LI DPYA++LV  AGAGA W  + D 
Sbjct  4    LRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEGAGAGA-WRFIADE  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             LVAKA+  D E  A+  ++++YQAVRT+FFD +F++AV AG+ Q+VILASGLDSRA+RL
Sbjct  63   DLVAKASESDPEVGALFEHMKNYQAVRTHFFDAFFSAAVDAGVSQIVILASGLDSRAFRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
             WPAGT+VYEIDQP VL YKS+TLA +GV P+A RREVP DLRQDWPA L   GFDP   
Sbjct  123  PWPAGTVVYEIDQPLVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAELVATGFDPARP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+  +S  GS++AAE+  VH  +RR  MR RF  +A  
Sbjct  183  TAWLAEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPDRRERMRERFASIASQ  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMAD-DPT  299
            + IE  +D+ EL Y D DRA VA+WL  HGW A++  + D MRR+ R+VE   +AD D  
Sbjct  243  IDIE-PMDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYVE---VADSDGQ  298

Query  300  AFAEFVTAERL  310
            +F+ F T  +L
Sbjct  299  SFSTFTTGTKL  309


>gi|120401132|ref|YP_950961.1| putative methyltransferase [Mycobacterium vanbaalenii PYR-1]
 gi|221222837|sp|A1T1A5.1|Y104_MYCVP RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mvan_0104
 gi|119953950|gb|ABM10955.1| putative methyltransferase [Mycobacterium vanbaalenii PYR-1]
Length=309

 Score =  313 bits (803),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 186/308 (61%), Positives = 228/308 (75%), Gaps = 6/308 (1%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT +DTWDI +SVGATAVMVAAARA ET+RP+PLI DPYA++LV  AG GA W+ + D 
Sbjct  4    LRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYAKILVAGAGNGA-WQYIADD  62

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
              VAK    D E   +  ++++YQAVRT+FFD +FA+AV AGIRQ+VILASGLDSRA+RL
Sbjct  63   GFVAKVTESDPEIGPLFEHMKNYQAVRTHFFDAFFAAAVDAGIRQIVILASGLDSRAFRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
             WPAGT V+EIDQP VL+YKS+TLA +GV P+A RREVP DLRQDWP AL  AGFD    
Sbjct  123  PWPAGTTVFEIDQPLVLAYKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLLMYLPA+AQDRLF Q+  +S  GSR+AAE+  +H ++RR  MR RF  +   
Sbjct  183  TAWLAEGLLMYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQDRRERMRERFASITAQ  242

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMAD-DPT  299
              +E  +D+ EL Y D DRA VA WLT HGWRA +  + DEMRR+ R VE   +AD D  
Sbjct  243  FDVE-PMDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRLHRLVE---IADGDDQ  298

Query  300  AFAEFVTA  307
            +F+ F TA
Sbjct  299  SFSTFTTA  306


>gi|169631681|ref|YP_001705330.1| hypothetical protein MAB_4607c [Mycobacterium abscessus ATCC 
19977]
 gi|221222939|sp|B1ML31.1|Y4607_MYCA9 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAB_4607c
 gi|169243648|emb|CAM64676.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=305

 Score =  279 bits (714),  Expect = 3e-73, Method: Compositional matrix adjust.
 Identities = 165/308 (54%), Positives = 197/308 (64%), Gaps = 30/308 (9%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MR   DTWDI +SVGATA+ VAAARA ET R D LIRDP+A++LV   G    WE ++  
Sbjct  1    MRVDGDTWDITSSVGATALGVAAARATETLRADALIRDPFAQILVDATGKATGWERLV--  58

Query  61   TLVAKAAAID---AETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRA  117
                 A  ID    E   I   +  YQA RT+FFD YF +A AAGIRQVVILASGLDSRA
Sbjct  59   -----AGDIDWPDPEAGRIYDRMVDYQATRTHFFDEYFLAAAAAGIRQVVILASGLDSRA  113

Query  118  YRLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDP  177
            YRLDWPAGT VYEIDQP+VL +K + LA +   P+A RR V  DLR+DWPAALR AGFD 
Sbjct  114  YRLDWPAGTTVYEIDQPQVLKFKDSALAAH--QPTAQRRGVAIDLREDWPAALRAAGFDS  171

Query  178  TARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPV-----HGEE---RRAE  229
               TAWLAEGLL YLPA+AQD LF  +G +S AGSR+A E           EE   RR +
Sbjct  172  AQPTAWLAEGLLPYLPADAQDNLFRDIGVLSAAGSRVAVEGYEGKLVLDESEEEAVRREQ  231

Query  230  MRARFKKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWV  289
            +RA FK   DV      + ++ L+Y D++RA  A+WL  HGW      A DEM R+GR  
Sbjct  232  VRAAFKTAIDV-----DVTIENLIYEDENRADPAEWLDAHGWSVTKTDAHDEMARLGR--  284

Query  290  EGVPMADD  297
               P+A+D
Sbjct  285  ---PVAED  289


>gi|342859421|ref|ZP_08716075.1| hypothetical protein MCOL_11093 [Mycobacterium colombiense CECT 
3035]
 gi|342133662|gb|EGT86865.1| hypothetical protein MCOL_11093 [Mycobacterium colombiense CECT 
3035]
Length=302

 Score =  278 bits (710),  Expect = 9e-73, Method: Compositional matrix adjust.
 Identities = 163/301 (55%), Positives = 199/301 (67%), Gaps = 19/301 (6%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MR+  D+W I   VGATA+ VAA+RA ET  PDPLIRD +ARLLV++AG    W  + DP
Sbjct  1    MRSAGDSWTITELVGATALGVAASRAAETAGPDPLIRDDFARLLVSSAGPA--WARLADP  58

Query  61   TLVAKAAAIDAETAAIVAYLRS--YQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAY  118
             L      +D +     A+     YQAVRT+FFD YFA+A  AGIRQVVILA+GLDSRAY
Sbjct  59   EL----GWLDGDEHGQRAHRCGIDYQAVRTHFFDEYFANAAGAGIRQVVILAAGLDSRAY  114

Query  119  RLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPT  178
            RLDWPAGT VYEIDQP+VL YK+  L ++G  PSA R  V  DLR DWPAAL  AGFD T
Sbjct  115  RLDWPAGTTVYEIDQPQVLEYKAGILQQHGAVPSALRHPVAVDLRDDWPAALTAAGFDRT  174

Query  179  ARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVA  238
              TAWLAEGLL YLP++AQDRLF  V A+S   S+IA E   + G   R+  + R+ ++ 
Sbjct  175  RPTAWLAEGLLPYLPSDAQDRLFEMVTALSAPDSQIAIE---MFGLNSRSNSQ-RWLRMR  230

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDP  298
            D LG++  ++VQ L YH+ DR+  A WL DHGW   S    DEM R+GR     P+ DD 
Sbjct  231  DRLGLD--VNVQALTYHEPDRSDAAAWLADHGWHVHSVSNRDEMARLGR-----PVPDDL  283

Query  299  T  299
            T
Sbjct  284  T  284


>gi|254822360|ref|ZP_05227361.1| methyltransferase, putative, family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=302

 Score =  273 bits (697),  Expect = 3e-71, Method: Compositional matrix adjust.
 Identities = 157/297 (53%), Positives = 195/297 (66%), Gaps = 15/297 (5%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MR+  D+W I   VGATA+ VAA+RA ET   DPLIRD +ARLLV++AG    W  + DP
Sbjct  1    MRSAGDSWSITELVGATALGVAASRAAETAGADPLIRDEFARLLVSSAGPA--WARLADP  58

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             L   A       A        YQAVRT+FFD YF  AV +GIRQ VILA+GLDSRAYRL
Sbjct  59   ELSWLADDQHGRRAHRTGI--DYQAVRTHFFDEYFDGAVRSGIRQAVILAAGLDSRAYRL  116

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWP GT VYEIDQPKVL YKS  L ++G  P+A R  VPADLR+DWP AL  AGFD T  
Sbjct  117  DWPTGTTVYEIDQPKVLQYKSGILQQHGAVPTAIRHPVPADLREDWPTALAAAGFDRTQP  176

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL YLP++AQDRLF  + A+S  GS++A E   V G   R+  + R+ ++ + 
Sbjct  177  TAWLAEGLLPYLPSDAQDRLFEMLTALSAPGSQVAIE---VFGINSRSNSQ-RWLRMRER  232

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADD  297
            LG++  ++VQ L YH+ DR+  A WL+DHGW   +    +EM R+GR     P+ DD
Sbjct  233  LGLD--VNVQALTYHEPDRSDAAAWLSDHGWHVHAVDNREEMARLGR-----PVPDD  282


>gi|169631680|ref|YP_001705329.1| hypothetical protein MAB_4606c [Mycobacterium abscessus ATCC 
19977]
 gi|221222938|sp|B1ML30.1|Y4606_MYCA9 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAB_4606c
 gi|169243647|emb|CAM64675.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=316

 Score =  265 bits (676),  Expect = 9e-69, Method: Compositional matrix adjust.
 Identities = 159/290 (55%), Positives = 193/290 (67%), Gaps = 5/290 (1%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            R+ DD+WDI +SVGATAVMVAAARA ET    PLI+DP+A+LLV  AG+GA W  +    
Sbjct  8    RSDDDSWDIASSVGATAVMVAAARAAETRSASPLIQDPFAQLLVERAGSGA-WSVLASDG  66

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L  + A +D +   ++ Y   YQAVRT FFD +F  A  AGI QVVILA+GLDSRAYRLD
Sbjct  67   LRQQLAELDPDADRVMQYAVDYQAVRTRFFDGFFERAAHAGITQVVILAAGLDSRAYRLD  126

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAGT VYEIDQP VL YK  TL  + V  +  RREVP DLRQDWPAAL+  GFD    T
Sbjct  127  WPAGTTVYEIDQPLVLQYKRHTLDAHDVRSACLRREVPVDLRQDWPAALQREGFDVAEPT  186

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEER---RAEMRARFKKVA  238
            AWLAEGLLMYLP EAQDRLF  +   S  GSRIA E      ++R   R++MRA F +  
Sbjct  187  AWLAEGLLMYLPTEAQDRLFELIVDQSAPGSRIAVEAVGPDNDKRQEFRSKMRAHFDRAR  246

Query  239  DVLGIE-QTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             + G++ +++DV  L+YHD++R  V  WL   GW  R+  A  EM   GR
Sbjct  247  KLAGMDGESLDVGSLMYHDENRTDVPQWLAGRGWTVRAIPAEVEMAEAGR  296


>gi|118464245|ref|YP_883578.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|221222928|sp|A0QKZ0.1|Y4444_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_4444
 gi|118165532|gb|ABK66429.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
Length=304

 Score =  263 bits (671),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 159/311 (52%), Positives = 189/311 (61%), Gaps = 14/311 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RTHDD WD+ +SVGATA MVAA RA+ T  P  LI DP+A  LV   G    +  M+D  
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVD-FFTKMMDGE  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L     AI+  T   +  +    AVRT +FD YF  A  AG+RQVVILASGLDSRAYRL 
Sbjct  62   L--DLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRQVVILASGLDSRAYRLP  119

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAGT+VYEIDQP+V+ +KS TLAE G  P+A RR +P DLR DWPAAL  AGFDP A T
Sbjct  120  WPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAAPT  179

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPV---HGEERRAEMRARFKKVA  238
            AWLAEGLL+YLP EAQDRLF  + A+S  GS IA E  P       ER  EM   F++  
Sbjct  180  AWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRE--  237

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDP  298
               G++  ID+  LVY  + R  V D+L   GWRA      +   R G  V   P  DDP
Sbjct  238  --HGVD--IDMASLVYAGE-RNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPA-PEHDDP  291

Query  299  TAFAEFVTAER  309
                 F++A R
Sbjct  292  LGEIIFISATR  302


>gi|254776879|ref|ZP_05218395.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=304

 Score =  261 bits (668),  Expect = 8e-68, Method: Compositional matrix adjust.
 Identities = 158/311 (51%), Positives = 188/311 (61%), Gaps = 14/311 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RTHDD WD+ +SVGATA MVAA RA+ T  P  LI DP+A  LV   G    +  M+D  
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVD-FFTKMMDGE  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L     AI+  T   +  +    AVRT +FD YF  A  AG+RQVVIL SGLDSRAYRL 
Sbjct  62   L--DLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRQVVILVSGLDSRAYRLP  119

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAGT+VYEIDQP+V+ +KS TLAE G  P+A RR +P DLR DWPAAL  AGFDP A T
Sbjct  120  WPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAAPT  179

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPV---HGEERRAEMRARFKKVA  238
            AWLAEGLL+YLP EAQDRLF  + A+S  GS IA E  P       ER  EM   F++  
Sbjct  180  AWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRE--  237

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDP  298
               G++  ID+  LVY  + R  V D+L   GWRA      +   R G  V   P  DDP
Sbjct  238  --HGVD--IDMASLVYAGE-RNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPA-PEHDDP  291

Query  299  TAFAEFVTAER  309
                 F++A R
Sbjct  292  LGEIIFISATR  302


>gi|41410287|ref|NP_963123.1| hypothetical protein MAP4189c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81412956|sp|Q73S87.1|Y4189_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_4189c
 gi|41399121|gb|AAS06739.1| hypothetical protein MAP_4189c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336460639|gb|EGO39530.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=304

 Score =  261 bits (667),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 158/311 (51%), Positives = 189/311 (61%), Gaps = 14/311 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RTHDD WD+ +SVGATA MVAA RA+ T  P  LI DP+A  LV   G    +  M+D  
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVD-FFTKMMDGE  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L     AI+  T   +  +    AVRT +FD YF  A  AG+R+VVILASGLDSRAYRL 
Sbjct  62   L--DLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRRVVILASGLDSRAYRLP  119

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAGT+VYEIDQP+V+ +KS TLAE G  P+A RR +P DLR DWPAAL  AGFDP A T
Sbjct  120  WPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAAPT  179

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPV---HGEERRAEMRARFKKVA  238
            AWLAEGLL+YLP EAQDRLF  + A+S  GS IA E  P       ER  EM   F++  
Sbjct  180  AWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRQ--  237

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDP  298
               G++  ID+  LVY  + R  V D+L   GWRA      +   R G  V   P  DDP
Sbjct  238  --HGVD--IDMASLVYAGE-RNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPA-PENDDP  291

Query  299  TAFAEFVTAER  309
                 F++A R
Sbjct  292  LGEIIFISATR  302


>gi|118466498|ref|YP_884267.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|254777492|ref|ZP_05219008.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
 gi|221222974|sp|A0QMX9.1|Y5150_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_5150
 gi|118167785|gb|ABK68682.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
Length=313

 Score =  261 bits (666),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 158/289 (55%), Positives = 196/289 (68%), Gaps = 14/289 (4%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT  D+W I   VGATA+ VAAARA ET  PDPLIRD +A LLV++AG    W  + DP
Sbjct  12   VRTAGDSWTITELVGATALGVAAARAAETAGPDPLIRDEFAGLLVSSAGPA--WARLADP  69

Query  61   TLVAKAAAIDAETAAIVAYLRS--YQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAY  118
                + + +D +     A+     YQAVRT++FD YF  A+ AGIRQVVILA+GLDSRAY
Sbjct  70   ----EQSWLDDDPHGKRAHRVGIDYQAVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAY  125

Query  119  RLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPT  178
            RL+WPAGT VYEIDQPKVL YK+ TL  +G TP+A RR VP DLR DWPAAL  AGF   
Sbjct  126  RLNWPAGTTVYEIDQPKVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAA  185

Query  179  ARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVA  238
              TAWLAEGLL YLP++AQDRLF  V A+S AGS++A E   V G   R+  + R+ ++ 
Sbjct  186  RPTAWLAEGLLPYLPSDAQDRLFEMVTALSAAGSQVAVE---VFGMNSRSNAQ-RWLRMR  241

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
            + LG++  ++V  L YH+ DR+  A WLT HGWR  S    DEM R+GR
Sbjct  242  ERLGLD--VNVAALTYHEPDRSDAAAWLTGHGWRVHSVDNRDEMARLGR  288


>gi|336459900|gb|EGO38812.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=313

 Score =  258 bits (659),  Expect = 7e-67, Method: Compositional matrix adjust.
 Identities = 156/287 (55%), Positives = 191/287 (67%), Gaps = 10/287 (3%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT  D+W I   VGATA+ VAAARA E+  PDPLIRD +A LLV++A     W  + DP
Sbjct  12   VRTAGDSWTITELVGATALGVAAARAAESAGPDPLIRDEFAGLLVSSASPA--WARLADP  69

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             L         + A  V     YQAVRT++FD YF  A+ AGIRQVVILA+GLDSRAYRL
Sbjct  70   ELSWLDDDPHGKRAHRVGI--DYQAVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRL  127

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            +WPAGT VYEIDQPKVL YK+ TL  +G TP+A RR VP DLR DWPAAL  AGF     
Sbjct  128  NWPAGTTVYEIDQPKVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARP  187

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL YLP++AQDRLF  V A+S AGS++A E   V G   R+  + R+ ++ + 
Sbjct  188  TAWLAEGLLPYLPSDAQDRLFEMVTALSAAGSQVAVE---VFGMNSRSNAQ-RWLRMRER  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
            LG++  ++V  L YH+ DR+  A WL  HGWR  S    DEM R+GR
Sbjct  244  LGLD--VNVAALTYHEPDRSDAAAWLARHGWRVHSVDNRDEMARLGR  288


>gi|41409661|ref|NP_962497.1| hypothetical protein MAP3563 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81413323|sp|Q73U05.1|Y3563_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_3563
 gi|41398493|gb|AAS06113.1| hypothetical protein MAP_3563 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=313

 Score =  258 bits (659),  Expect = 7e-67, Method: Compositional matrix adjust.
 Identities = 157/287 (55%), Positives = 191/287 (67%), Gaps = 10/287 (3%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +RT  D+W I   VGATA+ VAAARA ET  PDPLIRD +A LLV++A     W  + DP
Sbjct  12   VRTAGDSWTITELVGATALGVAAARAAETAGPDPLIRDEFAGLLVSSASPA--WARLADP  69

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             L         + A  V     YQAVRT++FD YF  A+ AGIRQVVILA+GLDSRAYRL
Sbjct  70   ELSWLDDDPHGKRAHRVGI--DYQAVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRL  127

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            +WPAGT VYEIDQPKVL YK+ TL  +G TP+A RR VP DLR DWPAAL  AGF     
Sbjct  128  NWPAGTTVYEIDQPKVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARP  187

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL YLP++AQDRLF  V A+S AGS++A E   V G   R+  + R+ ++ + 
Sbjct  188  TAWLAEGLLPYLPSDAQDRLFEMVTALSAAGSQVAVE---VFGMNSRSNAQ-RWLRMRER  243

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
            LG++  ++V  L YH+ DR+  A WL  HGWR  S    DEM R+GR
Sbjct  244  LGLD--VNVAALTYHEPDRSDAAAWLARHGWRVHSVDNRDEMARLGR  288


>gi|342861820|ref|ZP_08718465.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342130637|gb|EGT83941.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=306

 Score =  256 bits (654),  Expect = 3e-66, Method: Compositional matrix adjust.
 Identities = 152/311 (49%), Positives = 191/311 (62%), Gaps = 16/311 (5%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RTHDD WD+ +SVGATA MVAA RA+ T  P  LI DP+A  LV   G    +  M+D  
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLINDPFAEPLVRAVGVD-FFTKMMDGD  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L     AI+  +   +  +    AVRT +FD YF  +   G+RQVVILASGLDSRA+RL 
Sbjct  62   L--DVDAIENASPVRIQSMVDGMAVRTKYFDDYFIDSTGGGVRQVVILASGLDSRAFRLP  119

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAGT+VYEIDQP+V+ +KS TLA+ G  P+A RR +P DLR DWPAAL+ AGFD TA T
Sbjct  120  WPAGTVVYEIDQPRVIEFKSNTLADVGAEPTASRRTIPIDLRADWPAALKAAGFDTTAAT  179

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPV---HGEERRAEMRARFKKVA  238
            AWLAEGLL+YLP +AQDRLF  + A+S  GS IA E  P       ER  EM   F++  
Sbjct  180  AWLAEGLLIYLPPDAQDRLFDNITALSGPGSTIATEFVPGIVDFDAERVREMSGSFRE--  237

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEG-VPMADD  297
               G++  ID+  LVY  + R  V D+L+  GWRA      +   R G  +E   P  DD
Sbjct  238  --HGVD--IDMASLVYAGE-RNHVVDYLSSIGWRAEGITRTELFERNG--IEAPAPENDD  290

Query  298  PTAFAEFVTAE  308
            P     F++A+
Sbjct  291  PLGEIIFISAK  301


>gi|183980389|ref|YP_001848680.1| O-methyltransferase [Mycobacterium marinum M]
 gi|221222919|sp|B2HLS6.1|Y358_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_0358
 gi|183173715|gb|ACC38825.1| O-Methyltransferase [Mycobacterium marinum M]
Length=311

 Score =  253 bits (646),  Expect = 2e-65, Method: Compositional matrix adjust.
 Identities = 152/294 (52%), Positives = 178/294 (61%), Gaps = 12/294 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWE---AML  58
            RT DD+WDI TSVGATAVMVA ARA ET    PLIRD +A  LV+     A+ E   A  
Sbjct  3    RTADDSWDIATSVGATAVMVALARAAETASETPLIRDQFAEPLVSTPELAAVREQVAAWW  62

Query  59   DPTLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAY  118
              T          ++  +  YL    AVRT+FFD+YF  AVAAGIRQVVILA+GLDSRAY
Sbjct  63   AQTDDDDDPDFTVDSQQMTDYL----AVRTHFFDSYFIDAVAAGIRQVVILAAGLDSRAY  118

Query  119  RLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPT  178
            RLDWP GT VYEID PKVL YK  TLA +G  P A  R VP DLR DWP ALRDAGF  +
Sbjct  119  RLDWPGGTTVYEIDLPKVLDYKEHTLARHGAAPVAALRAVPVDLRHDWPQALRDAGFQTS  178

Query  179  ARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGE-----ERRAEMRAR  233
              TAWLAEGLL +LPA AQ  LFT + A S  GSR+A E   V  +     E RA+  AR
Sbjct  179  LPTAWLAEGLLPFLPAAAQHALFTAIDANSATGSRVAVEMFGVDEDARRAAEERAQRWAR  238

Query  234  FKKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             +      G + + D  +L + D+ +   ADW   HGW   S +A  E  R+GR
Sbjct  239  QRAKRQARGQDTSFDPFDLWFDDEGQPDPADWFAAHGWTTDSVQAGAEALRLGR  292


>gi|221222987|sp|A0PWG2.2|Y4761_MYCUA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MUL_4761
Length=311

 Score =  253 bits (646),  Expect = 3e-65, Method: Compositional matrix adjust.
 Identities = 151/294 (52%), Positives = 178/294 (61%), Gaps = 12/294 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWE---AML  58
            RT DD+WDI TSVGATAVMVA ARA ET    PLIRD +A  LV+     A+ E   A  
Sbjct  3    RTADDSWDIATSVGATAVMVALARAAETASETPLIRDQFAEPLVSTPELAAVREQVAAWW  62

Query  59   DPTLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAY  118
              T          ++  +  YL    AVRT+FFD+YF  AVAAGIRQVVILA+GLDSRAY
Sbjct  63   AQTDDDDDPDFTVDSQQMTDYL----AVRTHFFDSYFIDAVAAGIRQVVILAAGLDSRAY  118

Query  119  RLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPT  178
            RLDWP GT+VYEID PKVL YK  TLA +G  P A  R VP DLR DWP ALRDAGF  +
Sbjct  119  RLDWPGGTMVYEIDLPKVLDYKEHTLARHGAAPVAALRAVPVDLRHDWPQALRDAGFQTS  178

Query  179  ARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGE-----ERRAEMRAR  233
              TAWLAEGLL +LPA AQ  LFT + A S  GSR+A E   V  +     E RA+  AR
Sbjct  179  LPTAWLAEGLLPFLPAAAQHALFTAIDANSATGSRVAVEMFGVDEDARRAAEERAQRWAR  238

Query  234  FKKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             +      G + + D  +L + D+ +   ADW   HGW   S +   E  R+GR
Sbjct  239  QRAKRQARGQDTSFDPFDLWFDDEGQPDPADWFAAHGWTTDSVQVGAEALRLGR  292


>gi|221222875|sp|A0QNM1.2|Y093_MYCS2 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MSMEG_0093
Length=317

 Score =  252 bits (643),  Expect = 6e-65, Method: Compositional matrix adjust.
 Identities = 155/289 (54%), Positives = 190/289 (66%), Gaps = 6/289 (2%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +R+  D+W I  SVGATA+ VAAARA ET + DPLIRD +A LLV+ AG      A+ DP
Sbjct  7    VRSARDSWGITESVGATALGVAAARAAETAQADPLIRDEFAFLLVSAAGPTWAQMAVSDP  66

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
              +      DA+   I    R+YQAVRT++FD YF+    AGIRQVVILA+GLDSRA+RL
Sbjct  67   HWLGA----DADARRIHEISRNYQAVRTHYFDEYFSDVAHAGIRQVVILAAGLDSRAFRL  122

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT V+EIDQPKVL YK+ TL  +G    A    VPADLR DWPAAL +AGFDP   
Sbjct  123  DWPAGTTVFEIDQPKVLEYKTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQP  182

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL YLPA+AQDRLF  VG  S  GSRIA E   +  E    E RA+ +   + 
Sbjct  183  TAWLAEGLLPYLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGEQ  242

Query  241  L--GIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
            +   ++  IDV  L+Y   DRA  A WL++HGW+  +  + DEM R+GR
Sbjct  243  MRKQLDLDIDVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMARLGR  291


>gi|254818385|ref|ZP_05223386.1| methyltransferase, putative, family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=304

 Score =  251 bits (642),  Expect = 7e-65, Method: Compositional matrix adjust.
 Identities = 151/309 (49%), Positives = 186/309 (61%), Gaps = 14/309 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RTHDD WD+ +SVGATA MVAA RA+ T  P  LI DP+A  LV   G    +  M+D  
Sbjct  3    RTHDDNWDLASSVGATATMVAAGRAMATKDPRGLINDPFAEPLVRAVGV-EFFTKMMDGE  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L     AI+  ++  V  +     VRT +FD YF  AV AG+RQVVILASGLD+RAYRL 
Sbjct  62   L--DIDAIENASSVRVQAMIDGMTVRTRYFDDYFMDAVGAGVRQVVILASGLDARAYRLP  119

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WP GT+VYEIDQP+V+ +K++TLA  G  P+A RR V  DLR DWP AL+DAGFD TA T
Sbjct  120  WPDGTVVYEIDQPQVIEFKTSTLAGIGAEPTADRRTVGIDLRADWPTALKDAGFDTTAPT  179

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPV---HGEERRAEMRARFKKVA  238
            AWLAEGLL+YLP +AQDRLF  + A+S  GS IA E  P       E+  EM   F+   
Sbjct  180  AWLAEGLLIYLPPDAQDRLFDNITALSAPGSTIATEFVPGIVDFDAEKVREMSGSFRD--  237

Query  239  DVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMADDP  298
               G++  ID+  LVY   DR  V D+L+  GW A      +   R G  V   P  DDP
Sbjct  238  --HGVD--IDMASLVYT-GDRNHVVDYLSSTGWHAEGVTRTELFERGGFDVR-APEDDDP  291

Query  299  TAFAEFVTA  307
                 F++ 
Sbjct  292  LGEIVFISG  300


>gi|118468041|ref|YP_884509.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
 gi|118169328|gb|ABK70224.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
Length=320

 Score =  251 bits (642),  Expect = 8e-65, Method: Compositional matrix adjust.
 Identities = 155/289 (54%), Positives = 190/289 (66%), Gaps = 6/289 (2%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +R+  D+W I  SVGATA+ VAAARA ET + DPLIRD +A LLV+ AG      A+ DP
Sbjct  10   VRSARDSWGITESVGATALGVAAARAAETAQADPLIRDEFAFLLVSAAGPTWAQMAVSDP  69

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
              +      DA+   I    R+YQAVRT++FD YF+    AGIRQVVILA+GLDSRA+RL
Sbjct  70   HWLGA----DADARRIHEISRNYQAVRTHYFDEYFSDVAHAGIRQVVILAAGLDSRAFRL  125

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            DWPAGT V+EIDQPKVL YK+ TL  +G    A    VPADLR DWPAAL +AGFDP   
Sbjct  126  DWPAGTTVFEIDQPKVLEYKTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQP  185

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL YLPA+AQDRLF  VG  S  GSRIA E   +  E    E RA+ +   + 
Sbjct  186  TAWLAEGLLPYLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGEQ  245

Query  241  L--GIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
            +   ++  IDV  L+Y   DRA  A WL++HGW+  +  + DEM R+GR
Sbjct  246  MRKQLDLDIDVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMARLGR  294


>gi|118619535|ref|YP_907867.1| O-methyltransferase [Mycobacterium ulcerans Agy99]
 gi|221222923|sp|A0PVM7.1|Y4402_MYCUA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MUL_4402
 gi|118571645|gb|ABL06396.1| O-methyltransferase [Mycobacterium ulcerans Agy99]
Length=314

 Score =  251 bits (641),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 150/317 (48%), Positives = 199/317 (63%), Gaps = 17/317 (5%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +D+W I  SVGATA+ VAAARA ET+  +PLI DP+AR+ V  AG G +W    +P 
Sbjct  3    RTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDAAGDG-MWSMFANPA  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L+A A  I+++  A V  +  + A RT FFD +F  A  AG+RQVVILASGLDSRA+RL 
Sbjct  62   LLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFLGAADAGVRQVVILASGLDSRAWRLP  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WP GT+VYE+DQP+VL +KS TL ++G  P+A    +P DLRQDWPAAL D+GFD +  T
Sbjct  122  WPDGTVVYELDQPRVLEFKSATLRQHGARPTAQLMNIPIDLRQDWPAALLDSGFDASKPT  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHG------EERRAEMRARFK  235
            AW AEGL+ YLPA AQD LF ++  +S AGS +A    P  G        R+ E   R +
Sbjct  182  AWSAEGLVRYLPARAQDLLFERIDTLSPAGSWLATNV-PQGGFLDPDLVRRQHEEMQRMR  240

Query  236  KVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMA  295
              A  L +E  +   E +++ ++R  VADWL +HGWRA +  + + + R GR     P+ 
Sbjct  241  AAAGRL-VEIQMPAVEDLWYAEERTPVADWLGEHGWRASATTSAELLTRYGR-----PVP  294

Query  296  DD---PTAFAEFVTAER  309
            DD   P     FV+A R
Sbjct  295  DDAEGPVPPTLFVSAHR  311


>gi|183985291|ref|YP_001853582.1| O-methyltransferase [Mycobacterium marinum M]
 gi|221222975|sp|B2HLJ5.1|Y5323_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_5323
 gi|183178617|gb|ACC43727.1| O-methyltransferase [Mycobacterium marinum M]
Length=314

 Score =  250 bits (638),  Expect = 3e-64, Method: Compositional matrix adjust.
 Identities = 149/317 (48%), Positives = 198/317 (63%), Gaps = 17/317 (5%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +D+W I  SVGATA+ VAAARA ET+  +PLI DP+AR+ V  AG G +W    +P 
Sbjct  3    RTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDAAGDG-MWSMFANPA  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L+A A  I+++  A V  +  + A RT FFD +F  A   G+RQVVILASGLDSRA+RL 
Sbjct  62   LLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFLGAADTGVRQVVILASGLDSRAWRLP  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WP GT+VYE+DQP+VL +KS TL ++G  P+A    +P DLRQDWPAAL D+GFD +  T
Sbjct  122  WPDGTVVYELDQPRVLEFKSATLRQHGARPTAQLVNIPIDLRQDWPAALLDSGFDASKPT  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEE------RRAEMRARFK  235
            AW AEGL+ YLPA AQD LF ++  +S AGS +A    P  G        R+ E   R +
Sbjct  182  AWSAEGLVRYLPARAQDLLFERIDTLSPAGSWLAT-NVPQEGFSDPDLVRRQHEEMQRMR  240

Query  236  KVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMA  295
              A  L +E  +   E +++ ++R  VADWL +HGWRA +  + + + R GR     P+ 
Sbjct  241  AAAGRL-VEIQMPAVEDLWYAEERTPVADWLGEHGWRASATTSAELLTRYGR-----PVP  294

Query  296  DD---PTAFAEFVTAER  309
            DD   P     FV+A R
Sbjct  295  DDAEGPVPPTLFVSAHR  311


>gi|15610903|ref|NP_218284.1| hypothetical protein Rv3767c [Mycobacterium tuberculosis H37Rv]
 gi|15843387|ref|NP_338424.1| hypothetical protein MT3874 [Mycobacterium tuberculosis CDC1551]
 gi|31794937|ref|NP_857430.1| hypothetical protein Mb3793c [Mycobacterium bovis AF2122/97]
 82 more sequence titles
 Length=314

 Score =  249 bits (637),  Expect = 3e-64, Method: Compositional matrix adjust.
 Identities = 150/315 (48%), Positives = 199/315 (64%), Gaps = 13/315 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +D+W I  SVGATA+ VAAARA ET+  +PLI DP+AR+ V  AG G IW    + T
Sbjct  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDG-IWSMYTNRT  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L+A A  +D +  A +  +  + A RT FFD YF +   AG+RQVVILASGLDSRA+RL 
Sbjct  62   LLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLP  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WP GT+VYE+DQPKVL +KS TL ++G  P++    VP DLRQDWP AL+ AGFDP+   
Sbjct  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETA------PVHGEERRAEMRARFK  235
            AWLAEGL+ YLPA AQD LF ++ A+S  GS +A+         P     +RA+MR R +
Sbjct  182  AWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR-RMR  240

Query  236  KVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMA  295
              A  L   +  DV +L Y +Q R +VA+WL + GW   +   P+ + R GR    +P +
Sbjct  241  AAAAKLVETEISDVDDLWYAEQ-RTAVAEWLRERGWDVSTATLPELLARYGR---SIPHS  296

Query  296  -DDPTAFAEFVTAER  309
             +D      FV+A+R
Sbjct  297  GEDSIPPNLFVSAQR  311


>gi|221222872|sp|A1KEW5.2|Y181_MYCBP RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
BCG_0181
 gi|221222873|sp|A5TYM0.2|Y152_MYCTA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MRA_0152
 gi|221222874|sp|Q7U2R3.2|Y150_MYCBO RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mb0150
 gi|221222895|sp|P96822.3|Y153_MYCTU RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Rv0145/MT0153
Length=311

 Score =  247 bits (631),  Expect = 1e-63, Method: Compositional matrix adjust.
 Identities = 150/288 (53%), Positives = 189/288 (66%), Gaps = 14/288 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT  DTW I  SVGATA+ VAAARAVET   +PLIRD +A++LV++AG    W  + D  
Sbjct  9    RTAGDTWAITESVGATALGVAAARAVETAATNPLIRDEFAKVLVSSAGTA--WARLADAD  66

Query  62   LVAKAAAIDAETAA--IVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYR  119
            L    A +D +     +      YQAVRT+FFD YF +AV AG+RQVVILA+GLD+RAYR
Sbjct  67   L----AWLDGDQLGRRVHRVACDYQAVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYR  122

Query  120  LDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTA  179
            L+WPAGT+VYEIDQP VL YK+  L  +G  P+A R  V  DLR DWPAAL  AGFD T 
Sbjct  123  LNWPAGTVVYEIDQPSVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQ  182

Query  180  RTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVAD  239
             TAWLAEGLL YLP +A DRLF  V A+S  GS++A E   ++ +        R+ ++ +
Sbjct  183  PTAWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGN----TQRWNRMRE  238

Query  240  VLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             LG++  IDVQ L YH+ DR+  A WL  HGW+  S    +EM R+GR
Sbjct  239  RLGLD--IDVQALTYHEPDRSDAAQWLATHGWQVHSVSNREEMARLGR  284


>gi|15607287|ref|NP_214659.1| hypothetical protein Rv0145 [Mycobacterium tuberculosis H37Rv]
 gi|15839526|ref|NP_334563.1| hypothetical protein MT0153 [Mycobacterium tuberculosis CDC1551]
 gi|31791323|ref|NP_853816.1| hypothetical protein Mb0150 [Mycobacterium bovis AF2122/97]
 65 more sequence titles
 Length=317

 Score =  247 bits (630),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 150/288 (53%), Positives = 189/288 (66%), Gaps = 14/288 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT  DTW I  SVGATA+ VAAARAVET   +PLIRD +A++LV++AG    W  + D  
Sbjct  15   RTAGDTWAITESVGATALGVAAARAVETAATNPLIRDEFAKVLVSSAGTA--WARLADAD  72

Query  62   LVAKAAAIDAETAA--IVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYR  119
            L    A +D +     +      YQAVRT+FFD YF +AV AG+RQVVILA+GLD+RAYR
Sbjct  73   L----AWLDGDQLGRRVHRVACDYQAVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYR  128

Query  120  LDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTA  179
            L+WPAGT+VYEIDQP VL YK+  L  +G  P+A R  V  DLR DWPAAL  AGFD T 
Sbjct  129  LNWPAGTVVYEIDQPSVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQ  188

Query  180  RTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVAD  239
             TAWLAEGLL YLP +A DRLF  V A+S  GS++A E   ++ +        R+ ++ +
Sbjct  189  PTAWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGN----TQRWNRMRE  244

Query  240  VLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             LG++  IDVQ L YH+ DR+  A WL  HGW+  S    +EM R+GR
Sbjct  245  RLGLD--IDVQALTYHEPDRSDAAQWLATHGWQVHSVSNREEMARLGR  290


>gi|340625180|ref|YP_004743632.1| hypothetical protein MCAN_01481 [Mycobacterium canettii CIPT 
140010059]
 gi|340003370|emb|CCC42489.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=317

 Score =  246 bits (629),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 150/288 (53%), Positives = 188/288 (66%), Gaps = 14/288 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT  DTW I  SVGATA+ VAAARAVET   +PLIRD +A++LV++AG    W  + D  
Sbjct  15   RTAGDTWAITESVGATALGVAAARAVETAATNPLIRDEFAKVLVSSAGTA--WARLADAD  72

Query  62   LVAKAAAIDAETAA--IVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYR  119
            L    A +D +     +      YQAVRT+FFD YF +AV AG+RQVVILA+GLD+RAYR
Sbjct  73   L----AWLDGDQLGRRVHRVACDYQAVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYR  128

Query  120  LDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTA  179
            L+WPAGT+VYEIDQP VL YK   L  +G  P+A R  V  DLR DWPAAL  AGFD T 
Sbjct  129  LNWPAGTVVYEIDQPSVLEYKGGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQ  188

Query  180  RTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVAD  239
             TAWLAEGLL YLP +A DRLF  V A+S  GS++A E   ++ +        R+ ++ +
Sbjct  189  PTAWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGN----TQRWNRMRE  244

Query  240  VLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             LG++  IDVQ L YH+ DR+  A WL  HGW+  S    +EM R+GR
Sbjct  245  RLGLD--IDVQALTYHEPDRSDAAQWLATHGWQVHSVSNREEMARLGR  290


>gi|339630227|ref|YP_004721869.1| hypothetical protein MAF_01450 [Mycobacterium africanum GM041182]
 gi|339329583|emb|CCC25219.1| conserved hypothetical protein [Mycobacterium africanum GM041182]
Length=317

 Score =  246 bits (628),  Expect = 4e-63, Method: Compositional matrix adjust.
 Identities = 150/288 (53%), Positives = 188/288 (66%), Gaps = 14/288 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT  DTW I  SVGATA+ VAAARAVET   +PLIRD +A++LV++AG    W  + D  
Sbjct  15   RTAGDTWAITESVGATALGVAAARAVETAATNPLIRDEFAKVLVSSAGTA--WARLADAD  72

Query  62   LVAKAAAIDAETAA--IVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYR  119
            L    A +D +     +      YQAVRT+FFD YF +AV AG+RQVVILA+GLD+RAYR
Sbjct  73   L----AWLDGDQLGRRVHRVACDYQAVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYR  128

Query  120  LDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTA  179
            L+WPAGT+VYEIDQP VL YK+  L  +G  P A R  V  DLR DWPAAL  AGFD T 
Sbjct  129  LNWPAGTVVYEIDQPSVLEYKAGILQSHGAVPRARRHAVAVDLRDDWPAALIAAGFDGTQ  188

Query  180  RTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVAD  239
             TAWLAEGLL YLP +A DRLF  V A+S  GS++A E   ++ +        R+ ++ +
Sbjct  189  PTAWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGN----TQRWNRMRE  244

Query  240  VLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
             LG++  IDVQ L YH+ DR+  A WL  HGW+  S    +EM R+GR
Sbjct  245  RLGLD--IDVQALTYHEPDRSDAAQWLATHGWQVHSVSNREEMARLGR  290


>gi|183980387|ref|YP_001848678.1| hypothetical protein MMAR_0356 [Mycobacterium marinum M]
 gi|221222911|sp|B2HLS4.1|Y356_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_0356
 gi|183173713|gb|ACC38823.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=310

 Score =  244 bits (623),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 140/287 (49%), Positives = 183/287 (64%), Gaps = 10/287 (3%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            +R+  D+W +  SVGATA+ VAAARAVET   +PLIRD +A +LV++AG    W  + DP
Sbjct  10   LRSDGDSWTVTESVGATALGVAAARAVETAGANPLIRDEFAPILVSSAGPA--WARLADP  67

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
             +       D     +      YQAVRT+FFD YFA+A  AGI Q VILA+GLD RAYRL
Sbjct  68   DI--GWLDDDPHGQRLHRLGCDYQAVRTHFFDEYFAAAAGAGIEQAVILAAGLDCRAYRL  125

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
            +WP   +V+EIDQPKVL YK+  L  +GVT +A R  V  DLR+DWPAAL  AGFD    
Sbjct  126  NWPPEAVVFEIDQPKVLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRP  185

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHGEERRAEMRARFKKVADV  240
            TAWLAEGLL YLP +AQDRLF  +  +S   SRIA E+  ++        + R+ ++ D 
Sbjct  186  TAWLAEGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMN----LTGNKQRWNRMRDR  241

Query  241  LGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGR  287
            LG++  I+V+ L Y +  RA  A+WL +HGW+  S    +EM R+GR
Sbjct  242  LGLD--INVEALTYREPGRADAAEWLANHGWQVYSVSNREEMARLGR  286


>gi|240168533|ref|ZP_04747192.1| O-methyltransferase [Mycobacterium kansasii ATCC 12478]
Length=314

 Score =  244 bits (623),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 150/316 (48%), Positives = 199/316 (63%), Gaps = 15/316 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +D+WDI  SVGATA+ VAAARA ET+  +PLIRDP+AR+ V  AG G IW A  DP 
Sbjct  3    RTDNDSWDITESVGATALGVAAARAAETESENPLIRDPFARVFVDAAGEG-IWSAFADPR  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L+A+ A  +    + V  +  + A RT FFD +F  A  AG+RQVVILA+GLD+RA+RL 
Sbjct  62   LLAQVADSEPGVRSRVRAMVDFMATRTAFFDEFFLGAADAGVRQVVILAAGLDARAWRLP  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WP GT+VYE+DQPKVL +K+ TL  +G  P+A    VP DLRQDWP AL++AGFD +   
Sbjct  122  WPGGTVVYELDQPKVLDFKTATLRRHGARPTAELVNVPIDLRQDWPTALQEAGFDASKPC  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETAPVHG-------EERRAEMRARF  234
            AW AEGLL YLPA AQD LF ++ A S AGS +A    P  G         +R +M+   
Sbjct  182  AWSAEGLLRYLPATAQDLLFDRIDAQSTAGSWLACNV-PAAGFLDPDLVRRQREDMQRIR  240

Query  235  KKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPM  294
               A ++ +E T D+ +L Y  ++R +VADWL + GW+  +Q   + + R GR    VP 
Sbjct  241  AAAARLVKVEAT-DLDDLWYA-EERTAVADWLVERGWQVSAQTMTEVLARYGR---SVPS  295

Query  295  -ADDPTAFAEFVTAER  309
              +D      FV+A+R
Sbjct  296  DLEDSMPPTLFVSAQR  311


>gi|254819983|ref|ZP_05224984.1| methyltransferase [Mycobacterium intracellulare ATCC 13950]
Length=313

 Score =  243 bits (621),  Expect = 2e-62, Method: Compositional matrix adjust.
 Identities = 138/275 (51%), Positives = 169/275 (62%), Gaps = 7/275 (2%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +DTWDI  SVGATA+ VA  RA ET   DPLI DPYA+L +  AG G IW   LD  
Sbjct  3    RTDNDTWDINESVGATALGVAGGRAAETRSADPLISDPYAKLFLEAAGDG-IWRVYLDDE  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L A+    D +    +  +  Y A RT FFD YF +A   GIRQ+VILA+GLDSRA+RL 
Sbjct  62   LPAELVGADPQFEDRMQAMLGYTACRTKFFDDYFLAAAGEGIRQIVILAAGLDSRAWRLA  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAG +VYEIDQPKVL +K  TL  + V P A    V  DLR DWP AL  AGFD +A T
Sbjct  122  WPAGCVVYEIDQPKVLEFKIGTLKSHAVDPIASHVSVGIDLRLDWPKALAQAGFDASAPT  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAE--TAPVHGEE---RRAEMRARFKK  236
            AW AEGLL YL A+AQ  LF ++ ++S  GSR+A E  T      E   RR E   R+++
Sbjct  182  AWSAEGLLPYLTADAQGLLFDRIQSLSAPGSRVAVEAFTNEFFSPESFARREEQTERYRQ  241

Query  237  VADVLGIEQTIDVQELVYHDQDRASVADWLTDHGW  271
             A  LG +   +   L+Y +++R  V DWL  HGW
Sbjct  242  AAIRLGGKDITESGNLLY-EEERTEVVDWLQAHGW  275


>gi|118466717|ref|YP_881767.1| methyltransferase [Mycobacterium avium 104]
 gi|221222901|sp|A0QFS9.1|Y2576_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_2576
 gi|118168004|gb|ABK68901.1| methyltransferase [Mycobacterium avium 104]
Length=313

 Score =  243 bits (621),  Expect = 2e-62, Method: Compositional matrix adjust.
 Identities = 138/275 (51%), Positives = 169/275 (62%), Gaps = 7/275 (2%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +DTWDI  SVGATA+ VA  RA ET   DPLI DPYA+L +  AG G IW   LD  
Sbjct  3    RTDNDTWDINESVGATALGVAGGRAAETRSADPLISDPYAKLFLEAAGDG-IWRVYLDDE  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
            L A+    D +    +  +  Y A RT FFD YF +A   GIRQ+VILA+GLDSRA+RL 
Sbjct  62   LPAELVGADPQFEDRMQAMLGYTACRTKFFDDYFLAAAGEGIRQIVILAAGLDSRAWRLA  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WPAG +VYEIDQPKVL +K  TL  + V P A    V  DLR DWP AL  AGFD +A T
Sbjct  122  WPAGCVVYEIDQPKVLEFKIGTLKSHAVDPIASHVSVGIDLRLDWPKALAQAGFDASAPT  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAE--TAPVHGEE---RRAEMRARFKK  236
            AW AEGLL YL A+AQ  LF ++ ++S  GSR+A E  T      E   RR E   R+++
Sbjct  182  AWSAEGLLPYLTADAQGLLFDRIQSLSAPGSRVAVEAFTNEFFSPESFARREEQTERYRQ  241

Query  237  VADVLGIEQTIDVQELVYHDQDRASVADWLTDHGW  271
             A  LG +   +   L+Y +++R  V DWL  HGW
Sbjct  242  AAIRLGGKDITESGNLLY-EEERTEVVDWLQAHGW  275


>gi|183980567|ref|YP_001848858.1| O-methyltransferase [Mycobacterium marinum M]
 gi|221222976|sp|B2HNW1.1|Y539_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_0539
 gi|183173893|gb|ACC39003.1| O-Methyltransferase [Mycobacterium marinum M]
Length=301

 Score =  241 bits (616),  Expect = 8e-62, Method: Compositional matrix adjust.
 Identities = 133/292 (46%), Positives = 184/292 (64%), Gaps = 12/292 (4%)

Query  1    MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDP  60
            MR+  D+WDI TSVG+TA+ VA ARA+E  +PDPL  DPYA L     G    W  +LD 
Sbjct  1    MRSEGDSWDITTSVGSTALFVATARALEALKPDPLAVDPYAELFCRAVGGS--WADVLD-  57

Query  61   TLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRL  120
                 AA  + ++     +  ++Q  RT +FD YF  AV AG+RQVV+LA+GLDSRAYRL
Sbjct  58   ---GNAADHELQSDDFGKHFVNFQGARTKYFDAYFRRAVEAGVRQVVVLAAGLDSRAYRL  114

Query  121  DWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTAR  180
             WP GT ++E+D+P+VL +K   L  +GV P   RRE+  DLR DWP ALRD+GFD  A 
Sbjct  115  SWPDGTTIFELDRPQVLDFKREVLGGHGVRPRTERREIAVDLRDDWPQALRDSGFDAEAP  174

Query  181  TAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAE-TAPVHGEERRAEMRARFKKVAD  239
            +AW+AEGLL+YLPA AQ++LFT + +++  GS +A E  AP+   E  A++    ++ A 
Sbjct  175  SAWIAEGLLIYLPAAAQEQLFTGIDSLACLGSHVAVEDGAPLPDAEFAAKLEE--ERAAV  232

Query  240  VLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEG  291
              G E+     +L+Y+++  A  ADW ++HGW A      + +R VGR V G
Sbjct  233  AAGGERPF--FQLLYNER-CAPAADWFSEHGWTALGTPLNNYLREVGRPVPG  281


>gi|340628737|ref|YP_004747189.1| hypothetical protein MCAN_37871 [Mycobacterium canettii CIPT 
140010059]
 gi|340006927|emb|CCC46118.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=314

 Score =  241 bits (616),  Expect = 9e-62, Method: Compositional matrix adjust.
 Identities = 147/315 (47%), Positives = 196/315 (63%), Gaps = 13/315 (4%)

Query  2    RTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLLVTNAGAGAIWEAMLDPT  61
            RT +D+W I  SVGATA+ VAAARA ET+  +PLI DP+AR+ V  AG G +W      T
Sbjct  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDG-VWSMYAKAT  61

Query  62   LVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAGIRQVVILASGLDSRAYRLD  121
              A A  +D +  A +  +  + A RT FFD YF +A  AG+RQ+VILASGLDSRA+RL 
Sbjct  62   PRAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLAAADAGVRQIVILASGLDSRAWRLP  121

Query  122  WPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPADLRQDWPAALRDAGFDPTART  181
            WP GT+VYE+DQPKVL +KS TL ++G  P++    VP DLRQDWP AL+ AGFDP+   
Sbjct  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181

Query  182  AWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAETA------PVHGEERRAEMRARFK  235
            AW AEGL+ YLPA AQD LF ++ A+S  GS +A+         P     +RA+MR R +
Sbjct  182  AWSAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERLRRQRADMR-RMR  240

Query  236  KVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQRAPDEMRRVGRWVEGVPMA  295
              A  L   +  DV +L Y +Q R +VA+WL + GW   +   P+ + R GR    +P +
Sbjct  241  AAAAKLVETEISDVDDLWYAEQ-RTAVAEWLRERGWDVSTATLPELLARYGR---SIPHS  296

Query  296  -DDPTAFAEFVTAER  309
             +D      FV+A+R
Sbjct  297  GEDSIPPNLFVSAQR  311



Lambda     K      H
   0.319    0.131    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 530605165806




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40