BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0153c
Length=276
Score E
Sequences producing significant alignments: (Bits) Value
gi|83753747|pdb|1YWF|A Chain A, Crystal Structure Of Mycobacteri... 549 2e-154
gi|15607295|ref|NP_214667.1| phosphotyrosine protein phosphatase... 549 2e-154
gi|289756216|ref|ZP_06515594.1| phosphotyrosine protein phosphat... 547 6e-154
gi|31791331|ref|NP_853824.1| phosphotyrosine protein phosphatase... 547 8e-154
gi|298527544|ref|ZP_07014953.1| phosphotyrosine protein phosphat... 543 1e-152
gi|340625189|ref|YP_004743641.1| phosphotyrosine protein phospha... 539 2e-151
gi|339293218|gb|AEJ45329.1| ptbB, phosphotyrosine protein phosph... 506 2e-141
gi|183980404|ref|YP_001848695.1| phosphotyrosine protein phospha... 424 6e-117
gi|118619803|ref|YP_908135.1| phosphotyrosine protein phosphatas... 421 6e-116
gi|118462955|ref|YP_884262.1| phosphotyrosine protein phosphatas... 421 9e-116
gi|289748628|ref|ZP_06508006.1| phosphotyrosine protein phosphat... 402 3e-110
gi|254822355|ref|ZP_05227356.1| phosphotyrosine protein phosphat... 402 4e-110
gi|296167342|ref|ZP_06849744.1| phosphotyrosine protein phosphat... 394 6e-108
gi|342859416|ref|ZP_08716070.1| phosphotyrosine protein phosphat... 394 7e-108
gi|240168159|ref|ZP_04746818.1| phosphotyrosine protein phosphat... 386 2e-105
gi|333988737|ref|YP_004521351.1| phosphotyrosine protein phospha... 326 3e-87
gi|118470992|ref|YP_884517.1| phosphotyrosine protein phosphatas... 289 3e-76
gi|120401143|ref|YP_950972.1| protein tyrosine/serine phosphatas... 285 6e-75
gi|145221330|ref|YP_001132008.1| protein tyrosine/serine phospha... 285 8e-75
gi|315441786|ref|YP_004074665.1| protein tyrosine/serine phospha... 281 6e-74
gi|108797078|ref|YP_637275.1| protein tyrosine/serine phosphatas... 275 6e-72
gi|41409666|ref|NP_962502.1| hypothetical protein MAP3568c [Myco... 242 5e-62
gi|169631665|ref|YP_001705314.1| putative phosphotyrosine protei... 169 3e-40
gi|41409667|ref|NP_962503.1| hypothetical protein MAP3569c [Myco... 168 1e-39
gi|54026660|ref|YP_120902.1| hypothetical protein nfa46870 [Noca... 128 1e-27
gi|258653544|ref|YP_003202700.1| protein tyrosine/serine phospha... 119 5e-25
gi|337768925|emb|CCB77638.1| Protein tyrosine phosphatase [Strep... 111 9e-23
gi|229820531|ref|YP_002882057.1| protein tyrosine/serine phospha... 111 1e-22
gi|194014558|ref|ZP_03053175.1| putative protein-tyrosine-phosph... 107 2e-21
gi|297203861|ref|ZP_06921258.1| protein tyrosine phosphatase [St... 106 3e-21
gi|38324676|gb|AAR16515.1| RimC [Streptomyces diastaticus] 105 7e-21
gi|328886504|emb|CCA59743.1| hypothetical protein SVEN_6457 [Str... 103 2e-20
gi|167764053|ref|ZP_02436180.1| hypothetical protein BACSTE_0243... 103 2e-20
gi|345003402|ref|YP_004806256.1| protein tyrosine/serine phospha... 103 3e-20
gi|302541334|ref|ZP_07293676.1| conserved hypothetical protein [... 103 3e-20
gi|159038902|ref|YP_001538155.1| protein tyrosine/serine phospha... 102 6e-20
gi|291455369|ref|ZP_06594759.1| conventional protein tyrosine ph... 102 6e-20
gi|302537972|ref|ZP_07290314.1| tyrosine phosphatase [Streptomyc... 102 8e-20
gi|326444415|ref|ZP_08219149.1| hypothetical protein SclaA2_2525... 101 1e-19
gi|294816072|ref|ZP_06774715.1| Protein tyrosine phosphatase [St... 101 1e-19
gi|315641609|ref|ZP_07896677.1| putative protein-tyrosine-phosph... 101 1e-19
gi|302534102|ref|ZP_07286444.1| predicted protein [Streptomyces ... 100 2e-19
gi|269795766|ref|YP_003315221.1| protein tyrosine/serine phospha... 100 2e-19
gi|157692558|ref|YP_001487020.1| protein-tyrosine-phosphatase [B... 100 3e-19
gi|297190545|ref|ZP_06907943.1| protein tyrosine phosphatase [St... 100 3e-19
gi|299748023|ref|XP_001837406.2| hypothetical protein CC1G_01318... 99.8 4e-19
gi|302381765|ref|YP_003817588.1| protein tyrosine/serine phospha... 99.8 4e-19
gi|58336494|ref|YP_193079.1| protein tyrosine phosphatase [Lacto... 99.8 4e-19
gi|262200721|ref|YP_003271929.1| protein tyrosine/serine phospha... 99.4 5e-19
gi|315504715|ref|YP_004083602.1| protein tyrosine/serine phospha... 99.4 6e-19
>gi|83753747|pdb|1YWF|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis Protein
Tyrosine Phosphatase Ptpb
gi|146386663|pdb|2OZ5|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis Protein
Tyrosine Phosphatase Ptpb In Complex With The Specific Inhibitor
Omts
gi|146386664|pdb|2OZ5|B Chain B, Crystal Structure Of Mycobacterium Tuberculosis Protein
Tyrosine Phosphatase Ptpb In Complex With The Specific Inhibitor
Omts
Length=296
Score = 549 bits (1415), Expect = 2e-154, Method: Compositional matrix adjust.
Identities = 276/276 (100%), Positives = 276/276 (100%), Gaps = 0/276 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 21 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 80
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND
Sbjct 81 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 140
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 141 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 200
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA
Sbjct 201 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 260
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Sbjct 261 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 296
>gi|15607295|ref|NP_214667.1| phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase)
(PTPase) [Mycobacterium tuberculosis H37Rv]
gi|15839535|ref|NP_334572.1| hypothetical protein MT0162 [Mycobacterium tuberculosis CDC1551]
gi|148659917|ref|YP_001281440.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium tuberculosis
H37Ra]
64 more sequence titles
Length=276
Score = 549 bits (1415), Expect = 2e-154, Method: Compositional matrix adjust.
Identities = 276/276 (100%), Positives = 276/276 (100%), Gaps = 0/276 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND
Sbjct 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA
Sbjct 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Sbjct 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
>gi|289756216|ref|ZP_06515594.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium tuberculosis
EAS054]
gi|289696803|gb|EFD64232.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium tuberculosis
EAS054]
Length=276
Score = 547 bits (1410), Expect = 6e-154, Method: Compositional matrix adjust.
Identities = 275/276 (99%), Positives = 275/276 (99%), Gaps = 0/276 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND
Sbjct 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRDVIVADYLRSNDSVPQLRARISEMIQQRF TELAPEVVTFTKARLSDGVLGVRAEYLA
Sbjct 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFHTELAPEVVTFTKARLSDGVLGVRAEYLA 240
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Sbjct 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
>gi|31791331|ref|NP_853824.1| phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase)
(PTPase) [Mycobacterium bovis AF2122/97]
gi|121636065|ref|YP_976288.1| phosphotyrosine protein phosphatase ptpB [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224988538|ref|YP_002643225.1| phosphotyrosine protein phosphatase [Mycobacterium bovis BCG
str. Tokyo 172]
gi|31616916|emb|CAD93022.1| PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB (PROTEIN-TYROSINE-PHOSPHATASE)
(PTPase) [Mycobacterium bovis AF2122/97]
gi|121491712|emb|CAL70173.1| Phosphotyrosine protein phosphatase ptpB [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224771651|dbj|BAH24457.1| phosphotyrosine protein phosphatase [Mycobacterium bovis BCG
str. Tokyo 172]
gi|341600081|emb|CCC62750.1| Phosphotyrosine protein phosphatase ptpB [Mycobacterium bovis
BCG str. Moreau RDJ]
Length=276
Score = 547 bits (1409), Expect = 8e-154, Method: Compositional matrix adjust.
Identities = 275/276 (99%), Positives = 275/276 (99%), Gaps = 0/276 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTN GSNGESGESSQSIND
Sbjct 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNGGSNGESGESSQSIND 120
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA
Sbjct 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Sbjct 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
>gi|298527544|ref|ZP_07014953.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium tuberculosis
94_M4241A]
gi|298497338|gb|EFI32632.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium tuberculosis
94_M4241A]
Length=282
Score = 543 bits (1399), Expect = 1e-152, Method: Compositional matrix adjust.
Identities = 273/276 (99%), Positives = 273/276 (99%), Gaps = 0/276 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELP WNFRDVADTATALRP RLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 7 MAVRELPNTWNFRDVADTATALRPRRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 66
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND
Sbjct 67 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 126
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 127 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 186
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA
Sbjct 187 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 246
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Sbjct 247 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 282
>gi|340625189|ref|YP_004743641.1| phosphotyrosine protein phosphatase PTPB [Mycobacterium canettii
CIPT 140010059]
gi|340003379|emb|CCC42499.1| phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase)
(PTPase) [Mycobacterium canettii CIPT 140010059]
Length=276
Score = 539 bits (1389), Expect = 2e-151, Method: Compositional matrix adjust.
Identities = 271/276 (99%), Positives = 274/276 (99%), Gaps = 0/276 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELPGAWNFRDVADTATAL+PGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 1 MAVRELPGAWNFRDVADTATALQPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADD+ADDSAPHETAFKRLLTNDGSNGE GESSQSIND
Sbjct 61 VARRGPGRVPDGIDVHLLPFPDLADDEADDSAPHETAFKRLLTNDGSNGEYGESSQSIND 120
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTR+GAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 121 AATRYMTDEYRQFPTRSGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRDVIVADYLRSNDSVPQLRARISEMIQQR DTELAPEVVTFTKARLSDGVLGVRAEYLA
Sbjct 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRSDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
Sbjct 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
>gi|339293218|gb|AEJ45329.1| ptbB, phosphotyrosine protein phosphatase PtpB [Mycobacterium
tuberculosis CCDC5079]
Length=255
Score = 506 bits (1302), Expect = 2e-141, Method: Compositional matrix adjust.
Identities = 254/255 (99%), Positives = 255/255 (100%), Gaps = 0/255 (0%)
Query 22 LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFP 81
+RPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFP
Sbjct 1 MRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFP 60
Query 82 DLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQR 141
DLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQR
Sbjct 61 DLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQR 120
Query 142 ALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRA 201
ALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRA
Sbjct 121 ALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRA 180
Query 202 RISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAG 261
RISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAG
Sbjct 181 RISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAG 240
Query 262 ISQATVNRMRGVLLG 276
ISQATVNRMRGVLLG
Sbjct 241 ISQATVNRMRGVLLG 255
>gi|183980404|ref|YP_001848695.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium marinum
M]
gi|183173730|gb|ACC38840.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium marinum
M]
Length=276
Score = 424 bits (1091), Expect = 6e-117, Method: Compositional matrix adjust.
Identities = 215/274 (79%), Positives = 239/274 (88%), Gaps = 6/274 (2%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
ELPGAWNFRDVAD+ ALRPGRLFRSSELS LDD GRA LRR ITDVADLRSSREVARR
Sbjct 7 ELPGAWNFRDVADSTAALRPGRLFRSSELSGLDDQGRAALRRFKITDVADLRSSREVARR 66
Query 65 GPGRVPDGIDVHLLPFPDLADDDA--DDSAPHETAFKRLLTNDGSNGESGESSQSINDAA 122
GPG+VP G+DVHLLPFPDLADD A DD+APHETAFKRLLT+ G++GESS++I+ A
Sbjct 67 GPGQVPAGVDVHLLPFPDLADDQAGTDDNAPHETAFKRLLTD----GDAGESSEAIDQVA 122
Query 123 TRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDR 182
RYM DEYRQFP R GAQRA+HRV TLLAAGRPVLTHCFAGKDRTGFVVA VLEAVG+DR
Sbjct 123 ARYMADEYRQFPMRTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDR 182
Query 183 DVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAA 242
+VI+ADYLRSND+VPQLR RISEMI++R D EL PEVVTFTKARLSDGVLGVR EYLAAA
Sbjct 183 EVILADYLRSNDAVPQLRDRISEMIRERTDVELTPEVVTFTKARLSDGVLGVRPEYLAAA 242
Query 243 RQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
QTIDET+GSL GYL D+GI++A +++R LLG
Sbjct 243 WQTIDETFGSLDGYLADSGITEADRHQLRSALLG 276
>gi|118619803|ref|YP_908135.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium ulcerans
Agy99]
gi|118571913|gb|ABL06664.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium ulcerans
Agy99]
Length=276
Score = 421 bits (1082), Expect = 6e-116, Method: Compositional matrix adjust.
Identities = 213/274 (78%), Positives = 238/274 (87%), Gaps = 6/274 (2%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
ELPGAWNFRDVAD+ ALRPGRLFRSSELS LDD GRA LRR ITDVADLRSSREVARR
Sbjct 7 ELPGAWNFRDVADSTAALRPGRLFRSSELSGLDDQGRAALRRFKITDVADLRSSREVARR 66
Query 65 GPGRVPDGIDVHLLPFPDLADDDA--DDSAPHETAFKRLLTNDGSNGESGESSQSINDAA 122
GPG+VP G+DVHLLPFPDLADD A DD+APHETAFK LLT+ G++GESS++I+ A
Sbjct 67 GPGQVPAGVDVHLLPFPDLADDQAGTDDNAPHETAFKGLLTD----GDAGESSEAIDQVA 122
Query 123 TRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDR 182
RYM DEYRQFP R GAQRA+HRV TLLAAGRPVLTHCFAGKDRTGFVVA VLEAVG+DR
Sbjct 123 ARYMADEYRQFPMRTGAQRAVHRVFTLLAAGRPVLTHCFAGKDRTGFVVATVLEAVGVDR 182
Query 183 DVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAA 242
+VI+ADYLRSND+VPQLR R+SEMI++R D EL PEVVTFTKARLSDGVLGVR EYLAAA
Sbjct 183 EVILADYLRSNDAVPQLRDRVSEMIRERTDVELTPEVVTFTKARLSDGVLGVRPEYLAAA 242
Query 243 RQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
QTIDET+GSL GYL D+GI++A +++R LLG
Sbjct 243 WQTIDETFGSLDGYLADSGITEADRHQLRSALLG 276
>gi|118462955|ref|YP_884262.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium avium
104]
gi|254777487|ref|ZP_05219003.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium avium
subsp. avium ATCC 25291]
gi|118164242|gb|ABK65139.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium avium
104]
Length=276
Score = 421 bits (1081), Expect = 9e-116, Method: Compositional matrix adjust.
Identities = 212/276 (77%), Positives = 239/276 (87%), Gaps = 6/276 (2%)
Query 2 AVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREV 61
A+REL GAWNFRDVAD A LRPGRLFRS ELS LDD GRATLRRLGITDVADLR++REV
Sbjct 4 ALRELSGAWNFRDVADGAPMLRPGRLFRSGELSGLDDEGRATLRRLGITDVADLRAAREV 63
Query 62 ARRGPGRVPDGIDVHLLPFPDLADDDA--DDSAPHETAFKRLLTNDGSNGESGESSQSIN 119
ARRGPGRVPDG++VHLLPFPDL + +A DD APHE AF+RLLT DG+ +S++S++
Sbjct 64 ARRGPGRVPDGVEVHLLPFPDLGEHEAGTDDQAPHEHAFQRLLTGDGAE----QSAESVD 119
Query 120 DAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVG 179
+AATRYM DEYRQFPTRNGAQRALHRV++LLAAGR VLTHCFAGKDRTGFVVA VLEAVG
Sbjct 120 EAATRYMIDEYRQFPTRNGAQRALHRVISLLAAGRAVLTHCFAGKDRTGFVVATVLEAVG 179
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
+DRDVIVAD+LRSND+ P LRA+IS MI QR DTEL PEVVT+T+ARLSDGVLGVR EYL
Sbjct 180 VDRDVIVADFLRSNDAAPALRAQISAMIAQRQDTELTPEVVTWTEARLSDGVLGVREEYL 239
Query 240 AAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLL 275
AAARQTIDE +GSL YLRDAG+ +A V R+R LL
Sbjct 240 AAARQTIDEKFGSLQAYLRDAGVGEADVQRLRAALL 275
>gi|289748628|ref|ZP_06508006.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium tuberculosis
T92]
gi|289689215|gb|EFD56644.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium tuberculosis
T92]
Length=201
Score = 402 bits (1033), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
Sbjct 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND
Sbjct 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
Sbjct 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
Query 181 DRDVIVADYLRSNDSVPQLRA 201
DRDVIVADYLRSNDSVPQLRA
Sbjct 181 DRDVIVADYLRSNDSVPQLRA 201
>gi|254822355|ref|ZP_05227356.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium intracellulare
ATCC 13950]
Length=276
Score = 402 bits (1032), Expect = 4e-110, Method: Compositional matrix adjust.
Identities = 203/276 (74%), Positives = 231/276 (84%), Gaps = 6/276 (2%)
Query 2 AVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREV 61
A+REL GAWNFRDV+D A AL+PGRLFRS ELS LDD GRATL RLGITDVADLR++REV
Sbjct 4 ALRELSGAWNFRDVSDGAPALKPGRLFRSGELSGLDDDGRATLSRLGITDVADLRAAREV 63
Query 62 ARRGPGRVPDGIDVHLLPFPDLADDDA--DDSAPHETAFKRLLTNDGSNGESGESSQSIN 119
ARRGPG VPDG++VHLLPFPDL + DA DD+APHE AF+RLLT +G ES QS+N
Sbjct 64 ARRGPGLVPDGVEVHLLPFPDLGEQDAGTDDAAPHEHAFQRLLTGEGVE----ESEQSVN 119
Query 120 DAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVG 179
+AATRYM DEYRQFPTRNGAQRALHRV++LLA G VLTHCFAGKDRTGFVVA VLEA+G
Sbjct 120 EAATRYMIDEYRQFPTRNGAQRALHRVISLLADGHSVLTHCFAGKDRTGFVVATVLEAIG 179
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
+DRD I+AD+LRSND+ P LRA+IS MI QR D EL PEVVT+T+ARLSDGVLGVR YL
Sbjct 180 IDRDTILADFLRSNDAAPALRAQISAMIAQRQDAELTPEVVTWTEARLSDGVLGVREVYL 239
Query 240 AAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLL 275
AAARQTIDE +GSL YLR A +S++ V R+R LL
Sbjct 240 AAARQTIDEEFGSLDAYLRAASVSESDVERLREALL 275
>gi|296167342|ref|ZP_06849744.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295897286|gb|EFG76890.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=274
Score = 394 bits (1013), Expect = 6e-108, Method: Compositional matrix adjust.
Identities = 198/274 (73%), Positives = 223/274 (82%), Gaps = 6/274 (2%)
Query 3 VRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVA 62
+REL GAWNFRDVAD LRPGRLFRS ELSRLDD GRA LR LGITDVADLR+ REVA
Sbjct 5 LRELSGAWNFRDVADETPGLRPGRLFRSGELSRLDDEGRAMLRGLGITDVADLRAVREVA 64
Query 63 RRGPGRVPDGIDVHLLPFPDLADDD-ADDSAPHETAFKRLLTNDGSNGESGESSQSINDA 121
RRGPG VPDG+D+HLLPFPDL D++ +D APHETAF+RL G +S + +N+A
Sbjct 65 RRGPGLVPDGVDIHLLPFPDLGDEEPTEDDAPHETAFRRLF-----EGNPDQSDEEVNEA 119
Query 122 ATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLD 181
A R+M DEYRQFP+RNGAQRA+ V +LLAAGR VLTHCFAGKDRTGFV+A VLE VG+D
Sbjct 120 AVRHMIDEYRQFPSRNGAQRAVRHVFSLLAAGRSVLTHCFAGKDRTGFVIATVLETVGID 179
Query 182 RDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAA 241
RD IVADYLRSN +VPQLR I EMIQQR D EL PEVVTFTKARL+DGVLGVR EYLAA
Sbjct 180 RDTIVADYLRSNAAVPQLRDHIYEMIQQRSDAELTPEVVTFTKARLADGVLGVRPEYLAA 239
Query 242 ARQTIDETYGSLGGYLRDAGISQATVNRMRGVLL 275
ARQ IDE YGSL YLRDAG++QA ++R+R LL
Sbjct 240 ARQAIDEAYGSLDAYLRDAGVAQADIDRLRNQLL 273
>gi|342859416|ref|ZP_08716070.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium colombiense
CECT 3035]
gi|342133657|gb|EGT86860.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium colombiense
CECT 3035]
Length=274
Score = 394 bits (1013), Expect = 7e-108, Method: Compositional matrix adjust.
Identities = 198/275 (72%), Positives = 227/275 (83%), Gaps = 6/275 (2%)
Query 2 AVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREV 61
A+REL GAWNFRDVAD A+ALRPGRLFRS ELSRLDD GRATLR LGITDVADLR+++EV
Sbjct 4 ALRELSGAWNFRDVADGASALRPGRLFRSGELSRLDDQGRATLRELGITDVADLRANQEV 63
Query 62 ARRGPGRVPDGIDVHLLPFPDLADDD-ADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
RRGPG VPDGI +H LP PDL DD +DD APHETAF+RL G++G+S + +N+
Sbjct 64 TRRGPGLVPDGIAIHRLPLPDLGDDQPSDDDAPHETAFRRLF-----EGDTGQSDEEVNE 118
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
AA R+M DEYRQFPTRNGAQRA+ +V ++LAAGR VLTHCFAGKDRTGFV+A VLE + +
Sbjct 119 AAVRHMIDEYRQFPTRNGAQRAVRQVFSMLAAGRSVLTHCFAGKDRTGFVIATVLEVLDV 178
Query 181 DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA 240
DRD IVADYLRSN +VPQLR I EMIQ+R D EL PEVVTFTKARL+DGVLGVR EYL
Sbjct 179 DRDTIVADYLRSNAAVPQLRDHIYEMIQKRSDVELTPEVVTFTKARLADGVLGVRPEYLD 238
Query 241 AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLL 275
AARQTID +GSL YLRDAG+S+A V R+RG LL
Sbjct 239 AARQTIDREFGSLNNYLRDAGVSEADVKRLRGELL 273
>gi|240168159|ref|ZP_04746818.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium kansasii
ATCC 12478]
Length=270
Score = 386 bits (991), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 210/278 (76%), Positives = 233/278 (84%), Gaps = 10/278 (3%)
Query 1 MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
MA ELPGAWNFRDVAD+ TALRPGRLFRSSELSRLDDAGR TLRRL ITDVADLRSSRE
Sbjct 1 MADLELPGAWNFRDVADS-TALRPGRLFRSSELSRLDDAGRETLRRLAITDVADLRSSRE 59
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSA--PHETAFKRLLTNDGSNGESGESSQSI 118
V RRGPGRVP G+D+HLLPFPDLADDDA A PHE AF+RL+T S +SI
Sbjct 60 VVRRGPGRVPAGVDIHLLPFPDLADDDAGTDADAPHEHAFRRLMT-------SSPDGESI 112
Query 119 NDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAV 178
+ AA RYMTDEYRQFPTR GAQRALHRVVTLLA GR VLTHCFAGKDRTGFVVA VLEAV
Sbjct 113 DQAAVRYMTDEYRQFPTRTGAQRALHRVVTLLAGGRAVLTHCFAGKDRTGFVVATVLEAV 172
Query 179 GLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEY 238
G+DR+ I+ D+LRSND+VP+LR +I+EMIQQR + EL PEVVTFT+ARLSDGVLGVR EY
Sbjct 173 GVDREAILTDFLRSNDAVPRLREQIAEMIQQRSEAELTPEVVTFTEARLSDGVLGVRPEY 232
Query 239 LAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
LAA+ QTIDET+GS+ YLR+AGI+ A V R+R LLG
Sbjct 233 LAASWQTIDETWGSVDAYLRNAGITPADVGRLRDGLLG 270
>gi|333988737|ref|YP_004521351.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium sp. JDM601]
gi|333484705|gb|AEF34097.1| phosphotyrosine protein phosphatase PtpB [Mycobacterium sp. JDM601]
Length=277
Score = 326 bits (835), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 165/272 (61%), Positives = 211/272 (78%), Gaps = 8/272 (2%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
+LPGAWNFRDV++T ALRPGRLFRSSELSRLDD GR L R+G+ DVADLRS REV RR
Sbjct 12 DLPGAWNFRDVSETTGALRPGRLFRSSELSRLDDRGREQLLRIGVADVADLRSPREVTRR 71
Query 65 GPGRVPDGIDVHLLPFPDLADDDA-DDSAPHETAFKRLLTNDGSNGESGESSQSINDAAT 123
GPG VPDG+D+HLLPFPDLA D A + S+PHE AF++++ + + D A
Sbjct 72 GPGLVPDGVDIHLLPFPDLAADQAPESSSPHEDAFRKMMAEK-------PDADTAADVAA 124
Query 124 RYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRD 183
RYM +EY++FPT G++RA+ RVV+LLAAGRPVL HCFAGKDRTGFVVA+VL+A G+DRD
Sbjct 125 RYMLEEYQRFPTLGGSRRAVQRVVSLLAAGRPVLAHCFAGKDRTGFVVAVVLQAAGVDRD 184
Query 184 VIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAAR 243
+VADYLRSN +VP LR RI +MI+ R + E+ PEV+TFT+ARLSD VLGVRA+YL AA
Sbjct 185 AVVADYLRSNTAVPVLRDRIMDMIRSRPEDEITPEVLTFTEARLSDEVLGVRADYLEAAH 244
Query 244 QTIDETYGSLGGYLRDAGISQATVNRMRGVLL 275
++I++ +GSL +L +G++ A + +R L+
Sbjct 245 RSIEQNFGSLDAFLHASGVTDADRDGLRAALV 276
>gi|118470992|ref|YP_884517.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium smegmatis
str. MC2 155]
gi|118172279|gb|ABK73175.1| phosphotyrosine protein phosphatase ptpb [Mycobacterium smegmatis
str. MC2 155]
Length=268
Score = 289 bits (740), Expect = 3e-76, Method: Compositional matrix adjust.
Identities = 152/270 (57%), Positives = 196/270 (73%), Gaps = 12/270 (4%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
EL GAWNFRDVA T +RPG L+RSSELS+L D GRA +RLGITDVADLRS +EV RR
Sbjct 10 ELGGAWNFRDVAQE-TGIRPGVLYRSSELSKLSDDGRAVFKRLGITDVADLRSHQEVQRR 68
Query 65 GPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATR 124
GPG+VPDG+ VHLLPF DD + APHE+ F+R+++ + +GE + ++A R
Sbjct 69 GPGQVPDGVAVHLLPF--HPDDTSGQDAPHESTFQRVMS-ESPDGED------VTESARR 119
Query 125 YMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDV 184
YMT+ Y +FPT GA A+ +VV+LLAAGRPV+ HCFAGKDRTGF VA VL+A G+DRD
Sbjct 120 YMTEVYEEFPTLPGAHNAVRQVVSLLAAGRPVIAHCFAGKDRTGFTVATVLDAAGVDRDD 179
Query 185 IVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQ 244
I AD+LRSN+++ LR RI + ++ R E PE++TF +ARL+D VLGVR EYLAAA +
Sbjct 180 IFADFLRSNEAITPLRNRIMDSVRARSGDE--PEIITFAEARLTDEVLGVREEYLAAAWK 237
Query 245 TIDETYGSLGGYLRDAGISQATVNRMRGVL 274
++E YGSL G++ AGIS + +R L
Sbjct 238 RLEEAYGSLSGFMTAAGISPEELTALRDAL 267
>gi|120401143|ref|YP_950972.1| protein tyrosine/serine phosphatase [Mycobacterium vanbaalenii
PYR-1]
gi|119953961|gb|ABM10966.1| protein tyrosine/serine phosphatase [Mycobacterium vanbaalenii
PYR-1]
Length=266
Score = 285 bits (728), Expect = 6e-75, Method: Compositional matrix adjust.
Identities = 148/272 (55%), Positives = 195/272 (72%), Gaps = 12/272 (4%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
EL GAWNFRDV++ T + PGR FR+SELS+LDD GRA L+ LG+TDVADLR+SRE+ R
Sbjct 7 ELSGAWNFRDVSEQ-TGVAPGRFFRASELSKLDDTGRAALKGLGVTDVADLRTSRELERH 65
Query 65 GPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATR 124
GPG VP G+++H LPF + AD +PHE AF+R++T+ + + + DAA R
Sbjct 66 GPGLVPAGVEIHHLPFVETMA--ADGESPHEHAFQRMMTDKPDD-------EPVADAAAR 116
Query 125 YMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDV 184
YMT+EY + T A+RA+HRVV LL + R VL HCFAGKDRTGF +A+VLEA G+DRD
Sbjct 117 YMTEEYGRIATAPFARRAVHRVVNLLGSERAVLAHCFAGKDRTGFTIAVVLEAAGVDRDA 176
Query 185 IVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQ 244
I+ADYLRSN +VP+LR I +++R APE++ +ARL+D VLGVR EYL +AR+
Sbjct 177 IMADYLRSNVAVPRLRESILATVRER--AVDAPEIMELAEARLTDAVLGVREEYLDSARR 234
Query 245 TIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
TID+ +GSL GYL A ++ + R+R VLLG
Sbjct 235 TIDDQFGSLTGYLESADVTDEDIRRLRKVLLG 266
>gi|145221330|ref|YP_001132008.1| protein tyrosine/serine phosphatase [Mycobacterium gilvum PYR-GCK]
gi|145213816|gb|ABP43220.1| protein tyrosine/serine phosphatase [Mycobacterium gilvum PYR-GCK]
Length=266
Score = 285 bits (728), Expect = 8e-75, Method: Compositional matrix adjust.
Identities = 154/273 (57%), Positives = 195/273 (72%), Gaps = 12/273 (4%)
Query 4 RELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVAR 63
REL GAWNFRDV++ A + PG LFRSSELS+LDD GR L G+TDVADLR++RE+ R
Sbjct 6 RELSGAWNFRDVSEPA-GIAPGHLFRSSELSKLDDDGRGALIGFGVTDVADLRTARELER 64
Query 64 RGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAAT 123
GPGRVP ++VH LPF + AD +PHE AF+R++T D +GE I +AA
Sbjct 65 HGPGRVPTEVEVHHLPFVETMA--ADGESPHEHAFQRMMT-DKPDGEP------IAEAAA 115
Query 124 RYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRD 183
RYM++EY + T AQRA+HRVVTLL +GR VL HCFAGKDRTGF VA+VLEA G+DRD
Sbjct 116 RYMSEEYGRIATAPLAQRAVHRVVTLLGSGRSVLAHCFAGKDRTGFTVAVVLEAAGVDRD 175
Query 184 VIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAAR 243
I+ADYLRSN++VPQLR I E I+ R APE++ F +ARL+D VLGVR +YL AR
Sbjct 176 AIMADYLRSNEAVPQLRESILETIRVR--AAEAPEIMEFAEARLTDSVLGVREDYLDVAR 233
Query 244 QTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
+T++ +GSL YL AG++ + R+R VL G
Sbjct 234 RTLEAEFGSLRDYLESAGVTDEDLARLRRVLHG 266
>gi|315441786|ref|YP_004074665.1| protein tyrosine/serine phosphatase [Mycobacterium sp. Spyr1]
gi|315260089|gb|ADT96830.1| protein tyrosine/serine phosphatase [Mycobacterium sp. Spyr1]
Length=266
Score = 281 bits (720), Expect = 6e-74, Method: Compositional matrix adjust.
Identities = 150/273 (55%), Positives = 194/273 (72%), Gaps = 12/273 (4%)
Query 4 RELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVAR 63
REL GAWNFRDV++ A + PG LFRSSELS+LDD GR L G+TDVADLR++RE+ R
Sbjct 6 RELSGAWNFRDVSEPA-GIAPGHLFRSSELSKLDDDGRGALIGFGVTDVADLRTARELER 64
Query 64 RGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAAT 123
GPGRVP ++VH LPF + AD +PHE AF+R++T D +GE I +AA
Sbjct 65 HGPGRVPTEVEVHHLPFVETMA--ADGESPHEHAFQRMMT-DKPDGEP------IAEAAA 115
Query 124 RYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRD 183
RYM++EY + T AQRA+HRVVTL+ +GR VL HCFAGKDRTGF +A+VLEA G+DRD
Sbjct 116 RYMSEEYGRIATAPLAQRAVHRVVTLIGSGRSVLAHCFAGKDRTGFTIAVVLEAAGVDRD 175
Query 184 VIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAAR 243
I+ADYLRSN++VPQLR I E ++ R APE++ +ARL+D VLGVR +YL AR
Sbjct 176 AIMADYLRSNEAVPQLRESILETVRLR--AAEAPEIMELAEARLTDAVLGVREDYLDVAR 233
Query 244 QTIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
+T++ +GSL GYL AG++ + R+R L G
Sbjct 234 RTLEAEFGSLRGYLESAGVTDEDLARLRRALHG 266
>gi|108797078|ref|YP_637275.1| protein tyrosine/serine phosphatase [Mycobacterium sp. MCS]
gi|119866163|ref|YP_936115.1| protein tyrosine/serine phosphatase [Mycobacterium sp. KMS]
gi|126432700|ref|YP_001068391.1| protein tyrosine/serine phosphatase [Mycobacterium sp. JLS]
gi|108767497|gb|ABG06219.1| protein tyrosine/serine phosphatase [Mycobacterium sp. MCS]
gi|119692252|gb|ABL89325.1| protein tyrosine/serine phosphatase [Mycobacterium sp. KMS]
gi|126232500|gb|ABN95900.1| protein tyrosine/serine phosphatase [Mycobacterium sp. JLS]
Length=266
Score = 275 bits (703), Expect = 6e-72, Method: Compositional matrix adjust.
Identities = 151/272 (56%), Positives = 188/272 (70%), Gaps = 12/272 (4%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
EL GAWNFRDV+ + T + PG FR+SELSRLDD GRA L G+TDVADLR+ RE+ R
Sbjct 7 ELSGAWNFRDVS-SHTGVAPGVFFRASELSRLDDEGRAALSGYGVTDVADLRTLRELERH 65
Query 65 GPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATR 124
GPGRVP G+D+H LPF + DA+ APHE AF+R++T D GES I AA R
Sbjct 66 GPGRVPAGVDIHHLPFIETVASDAE--APHEHAFQRMMT-DKPEGES------IAAAAAR 116
Query 125 YMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDV 184
YMT+EY + + AQRA+ +VVTLL +GR VL HCFAGKDRTGF VA+VLEA G+DR+
Sbjct 117 YMTEEYARIASAPLAQRAVRQVVTLLGSGRRVLAHCFAGKDRTGFTVAVVLEAAGVDREA 176
Query 185 IVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQ 244
++ADYL SN +VPQLR I +++R PEV+ +ARL++ VLGVR EYL AA +
Sbjct 177 VMADYLHSNTAVPQLRESILVTVRER--AAETPEVLEMAEARLTESVLGVREEYLDAAFR 234
Query 245 TIDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
TI YGSL GYL AG+S + R+R L G
Sbjct 235 TIAGEYGSLEGYLSAAGVSADELARLRSTLRG 266
>gi|41409666|ref|NP_962502.1| hypothetical protein MAP3568c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398498|gb|AAS06118.1| hypothetical protein MAP_3568c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336459895|gb|EGO38807.1| hypothetical protein MAPs_45380 [Mycobacterium avium subsp. paratuberculosis
S397]
Length=151
Score = 242 bits (617), Expect = 5e-62, Method: Compositional matrix adjust.
Identities = 118/151 (79%), Positives = 131/151 (87%), Gaps = 0/151 (0%)
Query 126 MTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI 185
M DEYRQFPTRNGAQRALHRV++LL AGR VLTHCFAGKDRTGFVVA VLEA+G+DRDVI
Sbjct 1 MIDEYRQFPTRNGAQRALHRVISLLGAGRAVLTHCFAGKDRTGFVVATVLEAIGVDRDVI 60
Query 186 VADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQT 245
VAD+LRSND+ P LRA+IS MI QR DTEL PEVVT+T+ARLSDGVLGVR EYLAAARQT
Sbjct 61 VADFLRSNDAAPALRAQISAMIAQRQDTELTPEVVTWTEARLSDGVLGVREEYLAAARQT 120
Query 246 IDETYGSLGGYLRDAGISQATVNRMRGVLLG 276
IDE +GSL YLRDAG+ +A V R+R LL
Sbjct 121 IDEKFGSLQAYLRDAGVGEADVQRLRAALLA 151
>gi|169631665|ref|YP_001705314.1| putative phosphotyrosine protein phosphatase [Mycobacterium abscessus
ATCC 19977]
gi|169243632|emb|CAM64660.1| Putative phosphotyrosine protein phosphatase [Mycobacterium abscessus]
Length=276
Score = 169 bits (429), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 114/269 (43%), Positives = 150/269 (56%), Gaps = 14/269 (5%)
Query 8 GAWNFRDV--ADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRG 65
G WNFRDV AD+ +RPG LFRSSELS L AG TLR G+TD+ DLRS E+AR G
Sbjct 19 GIWNFRDVGGADSPVTIRPGVLFRSSELSGLTPAGAQTLRAFGVTDLYDLRSPTEIARTG 78
Query 66 PGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRY 125
RV GI VH +PF A ++ APHE A+++++ + G + + + +
Sbjct 79 SDRVDGGIRVHEVPFATPAA--GEERAPHEIAYRQMMLESMTAGRGPDPASQVE-----F 131
Query 126 MTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI 185
M EYR+FP G AL VV L++G L HC AGKDRTG +V L+L +VG+D I
Sbjct 132 MLAEYRRFPELPGTLVALKAVVDQLSSGATALVHCAAGKDRTGLLVGLLLSSVGVDYADI 191
Query 186 VADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQT 245
ADYLRSN ++ +RA IS + PE+ A LSD VLGVR EYL +
Sbjct 192 AADYLRSNAAIGAMRAHISAQMNAA-----EPELAQTMAAMLSDEVLGVREEYLDTGFRQ 246
Query 246 IDETYGSLGGYLRDAGISQATVNRMRGVL 274
+ +GS L AG+ + +R L
Sbjct 247 VANVFGSPEAMLVAAGVDDDGLTALRAAL 275
>gi|41409667|ref|NP_962503.1| hypothetical protein MAP3569c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398499|gb|AAS06119.1| hypothetical protein MAP_3569c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336459894|gb|EGO38806.1| hypothetical protein MAPs_45370 [Mycobacterium avium subsp. paratuberculosis
S397]
Length=136
Score = 168 bits (425), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 86/113 (77%), Positives = 94/113 (84%), Gaps = 2/113 (1%)
Query 2 AVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREV 61
A+REL GAWNFRDVAD A LRPGRLFRS ELS LDD GRATLRRLGITDVADLR++REV
Sbjct 4 ALRELSGAWNFRDVADGAPMLRPGRLFRSGELSGLDDEGRATLRRLGITDVADLRAAREV 63
Query 62 ARRGPGRVPDGIDVHLLPFPDLADDDA--DDSAPHETAFKRLLTNDGSNGESG 112
ARRGPGRVPDG++VHLLPFPDL + +A DD APHE AF+RLLT DG G
Sbjct 64 ARRGPGRVPDGVEVHLLPFPDLGEHEAGTDDQAPHEHAFQRLLTGDGGRAVGG 116
>gi|54026660|ref|YP_120902.1| hypothetical protein nfa46870 [Nocardia farcinica IFM 10152]
gi|54018168|dbj|BAD59538.1| hypothetical protein [Nocardia farcinica IFM 10152]
Length=248
Score = 128 bits (321), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 95/263 (37%), Positives = 133/263 (51%), Gaps = 44/263 (16%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
L G +NFRD T +RPG L RS++LS LDD G ATLR L +TDV DLR RE
Sbjct 11 HLSGTFNFRDTGGLRTVDGAKVRPGVLLRSAQLSGLDDRGHATLRELRVTDVHDLRGLRE 70
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
+ G +P + + + PF D ++ PH+ SG++ D
Sbjct 71 IDHIGHDNLPADVRLRVTPF----DSRMGEAPPHD---------------SGDT-----D 106
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGKDRTGFVVALVLEAVG 179
A T +M + YR FP A A+ + + G VL HC AGKDRTG+ VA +L AVG
Sbjct 107 AFT-HMLEVYRAFPALPEANAAIVELAESIVRGDGAVLVHCAAGKDRTGWAVATLLRAVG 165
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
+ + ++ADYLRSN++VP LRA ++ + A S +LGVR EYL
Sbjct 166 VSEEDVLADYLRSNEAVPALRAMLTATMGP--------------GAEPSPDLLGVREEYL 211
Query 240 AAARQTIDETYGSLGGYLRDAGI 262
+++ E +G +L AG+
Sbjct 212 RIGTESVRELHGDHDSFLAAAGL 234
>gi|258653544|ref|YP_003202700.1| protein tyrosine/serine phosphatase [Nakamurella multipartita
DSM 44233]
gi|258556769|gb|ACV79711.1| protein tyrosine/serine phosphatase [Nakamurella multipartita
DSM 44233]
Length=250
Score = 119 bits (298), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 89/272 (33%), Positives = 128/272 (48%), Gaps = 38/272 (13%)
Query 8 GAWNFRDVADTATA---LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
G WNFRD+ T T +R G ++R + LS LD AG+ L +LG+TDV DLR E+ R
Sbjct 11 GTWNFRDIGGTPTPDGPVRHGLVYRCAVLSGLDPAGQEALVKLGVTDVFDLRGELEIERE 70
Query 65 GPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATR 124
G RVP I V + PF D + P A + + + + R
Sbjct 71 GRDRVPASISVSVTPF-----HPEDGTMPVHAAAADH-----------ADAATPLERSRR 114
Query 125 YMTDEYRQFPTRNGAQRALHRVVTLLA-AGRPVLTHCFAGKDRTGFVVALVLEAVGLDRD 183
Y Y P AQR++ ++ +A VL HC AGKDRTG+ +A +L +G DRD
Sbjct 115 Y----YAAIPVFGPAQRSVATILRAVADTDGSVLVHCAAGKDRTGWTIATLLSILGADRD 170
Query 184 VIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAAR 243
I+A+YL SN ++ LR + FD++ D +LGV +L A
Sbjct 171 SIMAEYLLSNAAIGSLRDWLRVKYGDDFDSD--------------DALLGVDPSFLHAGW 216
Query 244 QTIDETYGSLGGYLRDAGISQATVNRMRGVLL 275
+++ +GS GYL G+ +R LL
Sbjct 217 SSVERNFGSFDGYLAAIGVGPDVQEAIRARLL 248
>gi|337768925|emb|CCB77638.1| Protein tyrosine phosphatase [Streptomyces cattleya NRRL 8057]
Length=274
Score = 111 bits (278), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 103/278 (38%), Positives = 141/278 (51%), Gaps = 31/278 (11%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV ATA +R GRL+RS L+ ++ A L LG+ V D R+S +
Sbjct 16 ELTGVRNFRDVGGAATADGRRVRYGRLYRSGHLAHATESDAAFLASLGLHTVVDFRNSAD 75
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
+A GP G+ +P D P E A + DG + + ++
Sbjct 76 IALEGPDVELPGVRNVNMPLND----------PAEGADFWRVVRDG-DLSALRAALGEGR 124
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLA-AGRPVLTHCFAGKDRTGFVVALVLEAVG 179
AA R MT YR A+ R++ LLA PVL HC AGKDR G +A++L A+G
Sbjct 125 AAAR-MTRSYRSLILTRTAEHG--RLLALLADEAVPVLLHCAAGKDRAGTSIAVILLALG 181
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELA-PEVVTFTKARLSDGVLGVRAEY 238
++RDVI ADYL SN++ + R R + D LA PEV+ L + RAEY
Sbjct 182 VERDVIEADYLLSNEAHRRYRIR-----RANPDHPLAQPEVM-----ELLGPLFEARAEY 231
Query 239 LAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
LAAA TIDE +GS YL + G+++ R+R + L
Sbjct 232 LAAAFDTIDERWGSTERYLTEGLGLTEERRERLRDLFL 269
>gi|229820531|ref|YP_002882057.1| protein tyrosine/serine phosphatase [Beutenbergia cavernae DSM
12333]
gi|229566444|gb|ACQ80295.1| protein tyrosine/serine phosphatase [Beutenbergia cavernae DSM
12333]
Length=270
Score = 111 bits (278), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 93/266 (35%), Positives = 121/266 (46%), Gaps = 31/266 (11%)
Query 5 ELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARR 64
+LPG+WN RD A T T R G L+RS+ LS L DAGRA L LG+ V DLRS EV R
Sbjct 14 DLPGSWNARDSA-TLTGTRAGVLWRSATLSELTDAGRARLAELGVRTVVDLRSPVEVERD 72
Query 65 GPGRVPDGIDVHLLPFPDLAD-------DDADDSAPHETAFKRLLTNDGSNGESGESSQS 117
G + VH LP A + AP + L + G+ G+
Sbjct 73 GVDTAGGDVTVHALPVTAGAQVPGAVVAAEHHGGAPSGDGYLAALRAMLTQGDPGQG--- 129
Query 118 INDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGKDRTGFVVALVLE 176
A ++M D YR T + AL + L+A PVL HC AGKDRTG +V+
Sbjct 130 ----AAQFMEDTYRAIVTDPASTEALGTALQLVATSPGPVLVHCAAGKDRTGLLVSTAQR 185
Query 177 AVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRA 236
VG+ D + AD+L SN + Q R IS L P + + V
Sbjct 186 LVGVPTDRVEADFLYSNRAADQHRIGISA-------DGLDPAYLQPLRR--------VSL 230
Query 237 EYLAAARQTIDETYGSLGGYLRDAGI 262
YL AA + +D +G GY R G+
Sbjct 231 RYLHAAWEEVDAVHGGFDGYRRALGV 256
>gi|194014558|ref|ZP_03053175.1| putative protein-tyrosine-phosphatase [Bacillus pumilus ATCC
7061]
gi|194013584|gb|EDW23149.1| putative protein-tyrosine-phosphatase [Bacillus pumilus ATCC
7061]
Length=268
Score = 107 bits (267), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 83/272 (31%), Positives = 130/272 (48%), Gaps = 35/272 (12%)
Query 11 NFRDVADTAT----ALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGP 66
NFR+V T +R G ++RS++LSRL T LGI V DLR++ E P
Sbjct 13 NFREVGGLHTTDEMVIREGMIYRSADLSRLTKQDIETFSTLGIQTVCDLRTASERKSHPP 72
Query 67 GRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYM 126
VH+ PD P + R+L +G + T M
Sbjct 73 KIKEHNKIVHIPMHPD-------SKMPSKWTMFRMLVAEGKSF-----------TFTPIM 114
Query 127 TDEYRQFPTRNGAQRALHRVVTLLA--AGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDV 184
D Y+ T + + ++ TLL+ + P++ HC +GKDRTGF+ AL+ A G+
Sbjct 115 KDLYQSMLTERKEE--IQQLFTLLSDKSNYPLMLHCTSGKDRTGFLSALIQLAAGVPMSA 172
Query 185 IVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQ 244
++++Y+RSN+ V L R QQRF ++ + +K ++ +LGV+ +YL
Sbjct 173 VLSEYMRSNEGVKMLVRR-----QQRFVRMMS--LYRVSKEQI-QPLLGVQQDYLGDVLN 224
Query 245 TIDETYGSLGGYLRDAG-ISQATVNRMRGVLL 275
+ ETYGS YL +A I +A + M+ +LL
Sbjct 225 EMMETYGSAQRYLIEACDIPEAQLKEMKNILL 256
>gi|297203861|ref|ZP_06921258.1| protein tyrosine phosphatase [Streptomyces sviceus ATCC 29083]
gi|197711917|gb|EDY55951.1| protein tyrosine phosphatase [Streptomyces sviceus ATCC 29083]
Length=288
Score = 106 bits (265), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 93/279 (34%), Positives = 133/279 (48%), Gaps = 33/279 (11%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV TA +R G LFRS L+ A L LG+ + D R++ +
Sbjct 34 ELAGVRNFRDVGGLPTADGRRVRYGMLFRSGHLAHATAEDAAFLASLGLHTIFDFRNAAD 93
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
GP G+ LP D A+ T F +++ +G+ + + + D
Sbjct 94 QKLEGPDVDLPGVTNVNLPLSDPAEG---------TWFWKMV----RDGDIEQLRELLGD 140
Query 121 A-ATRYMTDEYRQFPTRNGAQ--RALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEA 177
A MT+ YR A+ R LH +L P L HC AGKDR G VA+ L A
Sbjct 141 GKAAERMTNSYRTMIKERTAEHSRVLH---SLAEDSTPALMHCAAGKDRAGLSVAVTLLA 197
Query 178 VGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAE 237
+G++R+ IVADYL SN + + R + + +PEV+ L + RAE
Sbjct 198 LGVEREAIVADYLESNAKHRRYKVRRTSTSADAY----SPEVM-----ELLSPLFEARAE 248
Query 238 YLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
YL AA +TI+ET+G + YLR+ G++ R+R LL
Sbjct 249 YLEAAFETIEETWGGVEAYLREGLGLTPEIRERLRERLL 287
>gi|38324676|gb|AAR16515.1| RimC [Streptomyces diastaticus]
Length=375
Score = 105 bits (262), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 91/279 (33%), Positives = 131/279 (47%), Gaps = 48/279 (17%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRS-SELSRLDDAGRATLRRLGITDVADLRSSR 59
L GA NFRDV TA ++ G L+RS + + LRRLGI DLR+
Sbjct 135 HLEGAANFRDVGGYRTADGRWVKMGVLYRSPTPCTSSPTPTWIKLRRLGIRTDFDLRTPG 194
Query 60 EVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIN 119
E A + P RVP G R + + E+
Sbjct 195 ERA-KAPDRVPAG--------------------------ARYVVANVIGEENSAELPPTA 227
Query 120 DAATRYMTDEYRQFPTRNGAQRALHRVVTLLA--AGRPVLTHCFAGKDRTGFVVALVLEA 177
+A+ R M + YRQF R A +A + + A P+L HC +GKDRTG+ A++L A
Sbjct 228 EASERLMAESYRQFVVRPSAAKAYRSLFRMAAEPGSYPLLYHCSSGKDRTGWATAVLLTA 287
Query 178 VGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAE 237
+G+DR+ ++ DYL SND + A +E+ +Q PE+ ARL VL RA
Sbjct 288 LGVDRETVMRDYLASNDYLAASNA--AELAKQ------PPEIA----ARLKP-VLETRAP 334
Query 238 YLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
YL AA ++ +G+ G YLR+ G++ + R+R LL
Sbjct 335 YLNAAFDEVEARFGTFGAYLREGLGLNAQELERLRAALL 373
>gi|328886504|emb|CCA59743.1| hypothetical protein SVEN_6457 [Streptomyces venezuelae ATCC
10712]
Length=273
Score = 103 bits (258), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 94/283 (34%), Positives = 134/283 (48%), Gaps = 33/283 (11%)
Query 1 MAVRELPGAWNFRDVADTAT----ALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLR 56
M EL NFRDV T A+ PGRLFRS L+ A A L LG+ V D R
Sbjct 13 MTEPELAEVRNFRDVGGLPTTDGRAVHPGRLFRSGHLAHATAADVAFLDSLGLHTVFDFR 72
Query 57 SSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQ 116
+ + GP G+ +P D AD F +L+ +G+ +
Sbjct 73 NLADRKIEGPDVELPGVRNVNIPLNDPADG---------KEFWKLV----RDGDIEQLRG 119
Query 117 SIND--AATRYMTDEYRQFPTRNGAQRALHRVVTLLAA-GRPVLTHCFAGKDRTGFVVAL 173
+ D AA R M+D YR+ + + R++ LA P L HC AGKDR G +A+
Sbjct 120 ILGDGKAAAR-MSDSYRKMVIERTEEHS--RILHALAEDSLPALMHCAAGKDRAGLSIAI 176
Query 174 VLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLG 233
L AVG++R+ I ADY++SND P R ++ + AP+ ++ L +
Sbjct 177 TLLAVGVEREAIEADYVKSND--PHRRYKVRR-------SSTAPDAMSAEVMELLSPLFD 227
Query 234 VRAEYLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
R EYL A +TI+ T+GS+ YL + +S AT R+R LL
Sbjct 228 ARVEYLRGAFETIEATWGSVDAYLSEGLKLSSATRERLRERLL 270
>gi|167764053|ref|ZP_02436180.1| hypothetical protein BACSTE_02436 [Bacteroides stercoris ATCC
43183]
gi|167698169|gb|EDS14748.1| hypothetical protein BACSTE_02436 [Bacteroides stercoris ATCC
43183]
Length=353
Score = 103 bits (258), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 86/285 (31%), Positives = 127/285 (45%), Gaps = 58/285 (20%)
Query 6 LPGAWNFRDVA-----DTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
+PG NFRD+ T +R G ++RS+E+ L+ + R L+ LGI + DLR+S E
Sbjct 110 IPGVQNFRDLGGYPSYSTKKQMRWGMIYRSAEIDSLECSSRRELKNLGIKTLIDLRASSE 169
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
+ R+ P + G +V +P LA D E K + + + +N
Sbjct 170 IGRQSP--LQKGFNVVHIP---LATGDM------EGILKGIREEKIKSDTVYRMVERMNR 218
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL 180
T EYRQ + L PV+ HC +GK RTG V ALVL A+G+
Sbjct 219 ILIDQYTKEYRQIFD-----------ILLDKNSYPVVIHCSSGKGRTGIVSALVLAALGI 267
Query 181 DRDVIVADYLRSND--SVP-------QLRARISEMIQQRFDTELAPEVVTFTKARLSDGV 231
+ D+I+ DY SND ++P QL AR E I F
Sbjct 268 NEDIIMEDYRLSNDYFNIPSASKYAYQLPARSQEAITTLF-------------------- 307
Query 232 LGVRAEYLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
R ++L AA+ + YG + YLR G+S+ + R+R +LL
Sbjct 308 -SAREDFLNAAKDEAERRYGDMDTYLRKGIGLSKNEIKRLRSILL 351
>gi|345003402|ref|YP_004806256.1| protein tyrosine/serine phosphatase [Streptomyces sp. SirexAA-E]
gi|344319028|gb|AEN13716.1| protein tyrosine/serine phosphatase [Streptomyces sp. SirexAA-E]
Length=269
Score = 103 bits (257), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 94/275 (35%), Positives = 133/275 (49%), Gaps = 33/275 (12%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV AT +R GRL+RS L+ ++ A L LG+ V D R++ +
Sbjct 13 ELTGVRNFRDVGGLATVDGRRVRYGRLYRSGHLAHATESDTAFLAGLGLHTVFDFRNAAD 72
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSI-- 118
DG DV L P + + S P + A L DG+ + +SI
Sbjct 73 -------HKLDGYDVEL---PGVRNVSIPLSDPADGAEFWRLVRDGNI----QQLRSILA 118
Query 119 NDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGKDRTGFVVALVLEA 177
D T M YR T A+ + RV+ LA P L HC AGKDR G +A+ L A
Sbjct 119 GDKGTERMIASYRSIITDRTAEHS--RVLHALAEDSVPALMHCAAGKDRAGLSIAVTLLA 176
Query 178 VGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAE 237
VG++R+ + ADYL+SND+ + + R S+ E+ L + + G R E
Sbjct 177 VGVEREAVEADYLKSNDAHRRYKVRRSDTSAAGMSDEV---------MELLNPLFGARPE 227
Query 238 YLAAARQTIDETYGSLGGYLRDA-GISQATVNRMR 271
YLAAA TI+ET+G YL + G++ T ++R
Sbjct 228 YLAAAFATIEETWGGTDRYLAEGLGLAPETREKLR 262
>gi|302541334|ref|ZP_07293676.1| conserved hypothetical protein [Streptomyces hygroscopicus ATCC
53653]
gi|302458952|gb|EFL22045.1| conserved hypothetical protein [Streptomyces himastatinicus ATCC
53653]
Length=271
Score = 103 bits (257), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 93/280 (34%), Positives = 128/280 (46%), Gaps = 33/280 (11%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV T LRPG LFRS L+ D+ A L LG+ V D R++ +
Sbjct 14 ELVGVRNFRDVGGLPTTDGRRLRPGVLFRSGHLAHATDSDAAFLDSLGLHTVFDFRNAAD 73
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHE---TAFKRLLTNDGSNGESGESSQS 117
+ GP G+ LP D AD + E + LL N
Sbjct 74 IKLEGPDVSLSGVRNVNLPLSDPADGAGFWTMVREGDLNTLRELLDNG------------ 121
Query 118 INDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAA-GRPVLTHCFAGKDRTGFVVALVLE 176
A R M + YR T + RV++ +A PVL HC AGKDR G VA+ L
Sbjct 122 ---RAERRMINAYRAIITSRIVEHG--RVLSAMAEDSSPVLMHCSAGKDRAGLSVAVTLL 176
Query 177 AVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRA 236
A+G++R+ I ADYL S + R +I ++PEV+ + R+
Sbjct 177 ALGVERESIEADYLES--AAAHRRYKIWRKGNPADGDPMSPEVLDLLSP-----LFDARS 229
Query 237 EYLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
YLAAA QTI+ET+G+ YL + G++ R+R +L
Sbjct 230 TYLAAAFQTIEETWGTTERYLTEGLGLTAPQRERLRDRML 269
>gi|159038902|ref|YP_001538155.1| protein tyrosine/serine phosphatase [Salinispora arenicola CNS-205]
gi|157917737|gb|ABV99164.1| protein tyrosine/serine phosphatase [Salinispora arenicola CNS-205]
Length=265
Score = 102 bits (254), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 96/278 (35%), Positives = 123/278 (45%), Gaps = 29/278 (10%)
Query 6 LPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREV 61
L GA N RD+ A +RPG L R+ L RL D L +L V DLR + E
Sbjct 8 LVGAPNARDLGGLVGAGGRRVRPGALLRTPALGRLTDEDLPVLAKLAPACVVDLRDTAEQ 67
Query 62 ARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDA 121
A P R+P V LP D A P T +L + G + +
Sbjct 68 AVAPPDRLPGEPQVVHLPVHDAAH-------PVFTYVSAVLLGH----DLGAYEELAEEG 116
Query 122 ATRYMTDEYRQFPTRNGAQRALHRVVTLL--AAGRPVLTHCFAGKDRTGFVVALVLEAVG 179
M YR F T A+ V L AA P+L HC AGKDRTG++ A++L A+G
Sbjct 117 TPAAMKSIYRWFVTGESARAGFGAAVRLAVEAANLPLLYHCSAGKDRTGWLTAVLLHALG 176
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEV-VTFTKARLSDGVLGVRAEY 238
+D I ADYL +N LR + +Q+R +PE+ V + VL VR EY
Sbjct 177 VDEATIRADYLANNALTESLREVLLAAMQRR-----SPELDVASVRP-----VLEVRDEY 226
Query 239 LAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
L A YGS G YLRD G+ V +R LL
Sbjct 227 LDAGYDEAGRVYGSFGSYLRDGLGVDDELVATLRARLL 264
>gi|291455369|ref|ZP_06594759.1| conventional protein tyrosine phosphatase [Streptomyces albus
J1074]
gi|291358318|gb|EFE85220.1| conventional protein tyrosine phosphatase [Streptomyces albus
J1074]
Length=271
Score = 102 bits (254), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 105/292 (36%), Positives = 136/292 (47%), Gaps = 51/292 (17%)
Query 1 MAVRELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLR 56
M EL G NFRDV TA +R G+LFRS L+ +A L LG+ V D R
Sbjct 13 MPEPELTGVRNFRDVGGLPTADGRRVRAGQLFRSGHLAHATEADTGFLSGLGLHTVFDFR 72
Query 57 SSREVARRGPGRVPDGIDVHL-------LPFPDLADDDADDSAPHETAFKRL--LTNDGS 107
+S + R DG+DV L +P D AD E +L L DG
Sbjct 73 NSAD-------RALDGLDVELPGVRNVNIPLSDPADGAGFWKMVREGDLPQLRSLLGDGK 125
Query 108 NGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGKDR 166
AA R MT YR+ T + + RV+ LA P L HC AGKDR
Sbjct 126 -------------AALR-MTTSYREMITGRTTEHS--RVLRSLAEESVPALMHCAAGKDR 169
Query 167 TGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTE--LAPEVVTFTK 224
G VA+ L A+G+DR+ I ADYL SN + R I++ D+ L+PEV+
Sbjct 170 AGLSVAVTLLALGVDREAIEADYLESNAQHRRYR------IRRASDSPDALSPEVM---- 219
Query 225 ARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
L + RAEYLAAA +TID T+G YL D ++ +R+ G LL
Sbjct 220 -ELLSPLFEARAEYLAAAFETIDATWGGTERYLTDGLRLTPELRDRLHGRLL 270
>gi|302537972|ref|ZP_07290314.1| tyrosine phosphatase [Streptomyces sp. C]
gi|302446867|gb|EFL18683.1| tyrosine phosphatase [Streptomyces sp. C]
Length=273
Score = 102 bits (253), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 99/278 (36%), Positives = 131/278 (48%), Gaps = 31/278 (11%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
E+ G NFRDV T +RPGRLFRS L+ + L LG+ V D R+ +
Sbjct 18 EMTGVRNFRDVGGLPTTDGRRVRPGRLFRSGHLAHATETDTEFLASLGLHTVFDFRNGAD 77
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
A GP G+ +P D AD + ++L G GE
Sbjct 78 HALEGPDVELPGVRNVNIPLTDPADGREFWKMVRDGELEQL------RGLLGEGR----- 126
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGKDRTGFVVALVLEAVG 179
AA R MTD YR A+ + RVV LA P L HC AGKDR G VA+ L A+G
Sbjct 127 AAAR-MTDSYRTIIRTRTAEHS--RVVHALALDSVPALMHCAAGKDRAGLSVAVTLLALG 183
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
++R+ I+ADYL SN VP R R+ APE + L + RAEYL
Sbjct 184 VEREAIMADYLESN--VPHNRYRVRRGSD-------APEARSPEVMELLAPLFDARAEYL 234
Query 240 AAARQTIDETYGSLGGYLRDAGISQA--TVNRMRGVLL 275
+A IDE +G + YL + G+S A +++R+R LL
Sbjct 235 LSAFAVIDEQWGGVERYLAE-GLSLAPESLDRLRDRLL 271
>gi|326444415|ref|ZP_08219149.1| hypothetical protein SclaA2_25256 [Streptomyces clavuligerus
ATCC 27064]
Length=270
Score = 101 bits (252), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 96/277 (35%), Positives = 129/277 (47%), Gaps = 29/277 (10%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV T +R GRLFRS L+ +A A L LG+ V D R++ +
Sbjct 14 ELTGVRNFRDVGGLPTTDGRRVRHGRLFRSGHLAHATEADAAFLDTLGLHTVFDFRNAAD 73
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
V GP G+ + +P D A F R++ + + S +
Sbjct 74 VRLEGPDVELPGVRLVSMPLSDPAAG---------AEFWRMVRE--GDLDQLRSILAEGR 122
Query 121 AATRYMTDEYRQFP-TRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVG 179
A R MTD YR R G L R L P L HC AGKDR G +A+ L AVG
Sbjct 123 GAAR-MTDSYRSMVLERTGEHGRLLR--ALAEDSVPALMHCAAGKDRAGLSIAVTLLAVG 179
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
++R+ + ADYL SND R + +APEV+ + R EYL
Sbjct 180 VEREAVEADYLVSNDP----HRRYRVRRRDDSPAAMAPEVMELLAP-----LFDARLEYL 230
Query 240 AAARQTIDETYGSLGGYL-RDAGISQATVNRMRGVLL 275
AA +T++ T+GS+ GYL R G++ AT R+R LL
Sbjct 231 RAAFETMERTWGSVEGYLGRGLGLAPATRERLRERLL 267
>gi|294816072|ref|ZP_06774715.1| Protein tyrosine phosphatase [Streptomyces clavuligerus ATCC
27064]
gi|294328671|gb|EFG10314.1| Protein tyrosine phosphatase [Streptomyces clavuligerus ATCC
27064]
Length=276
Score = 101 bits (252), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 96/277 (35%), Positives = 129/277 (47%), Gaps = 29/277 (10%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV T +R GRLFRS L+ +A A L LG+ V D R++ +
Sbjct 20 ELTGVRNFRDVGGLPTTDGRRVRHGRLFRSGHLAHATEADAAFLDTLGLHTVFDFRNAAD 79
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
V GP G+ + +P D A F R++ + + S +
Sbjct 80 VRLEGPDVELPGVRLVSMPLSDPAAG---------AEFWRMVRE--GDLDQLRSILAEGR 128
Query 121 AATRYMTDEYRQFP-TRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVG 179
A R MTD YR R G L R L P L HC AGKDR G +A+ L AVG
Sbjct 129 GAAR-MTDSYRSMVLERTGEHGRLLR--ALAEDSVPALMHCAAGKDRAGLSIAVTLLAVG 185
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
++R+ + ADYL SND R + +APEV+ + R EYL
Sbjct 186 VEREAVEADYLVSNDP----HRRYRVRRRDDSPAAMAPEVMELLAP-----LFDARLEYL 236
Query 240 AAARQTIDETYGSLGGYL-RDAGISQATVNRMRGVLL 275
AA +T++ T+GS+ GYL R G++ AT R+R LL
Sbjct 237 RAAFETMERTWGSVEGYLGRGLGLAPATRERLRERLL 273
>gi|315641609|ref|ZP_07896677.1| putative protein-tyrosine-phosphatase [Enterococcus italicus
DSM 15952]
gi|315482650|gb|EFU73178.1| putative protein-tyrosine-phosphatase [Enterococcus italicus
DSM 15952]
Length=248
Score = 101 bits (252), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 82/256 (33%), Positives = 115/256 (45%), Gaps = 35/256 (13%)
Query 11 NFRDVADTAT----ALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGP 66
NFRD+ T ++P RL RS EL +LD+ G+ L + +T V DLRS E+ +R P
Sbjct 5 NFRDLGGVKTKEGKVIKPNRLLRSGELVQLDEEGKKVLAQHQLTKVIDLRSEDELEKR-P 63
Query 67 GRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYM 126
ID + D ++A + ++GE +A R+M
Sbjct 64 DDALHTIDYQWIDIMK----DVKENASMDALL-----------QAGEL-----EAVDRHM 103
Query 127 TDEYRQFPTRNGAQRALHRVVTLLAAGRP--VLTHCFAGKDRTGFVVALVLEAVGLDRDV 184
Y GAQ+ + L A VL HCFAGKDRTG LE +G+ RD
Sbjct 104 KQIYTNLVMNEGAQKGYRQYFEQLLATETGGVLFHCFAGKDRTGMAAVYALELLGISRDA 163
Query 185 IVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQ 244
I DYL++N RA+ +E + F ELA + T + + V A YL A Q
Sbjct 164 IYQDYLQTNIQ----RAKPNESM---F-AELAKQGATKQQIAGVKIAMEVSASYLDHAYQ 215
Query 245 TIDETYGSLGGYLRDA 260
I YGS+ Y ++A
Sbjct 216 LIKTKYGSMQEYAKEA 231
>gi|302534102|ref|ZP_07286444.1| predicted protein [Streptomyces sp. C]
gi|302442997|gb|EFL14813.1| predicted protein [Streptomyces sp. C]
Length=264
Score = 100 bits (250), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 92/279 (33%), Positives = 130/279 (47%), Gaps = 40/279 (14%)
Query 11 NFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGP 66
N RD+ T A +RPG + R+ L RLD + LG+ V DLRS E A P
Sbjct 11 NLRDLGGTPLAGGRTVRPGLVLRAGALDRLDLDADPAVAALGLRTVIDLRSDAERADH-P 69
Query 67 GRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGE--SGESSQSINDAATR 124
R+PDG V L+ LAD +D P T K LL + E G +Q++ +
Sbjct 70 DRIPDG--VRLMVRDVLADKMSDHRMPAATQLKDLLGDPAVAEEHLGGGKAQALFGSV-- 125
Query 125 YMTDEYRQFPTRNGAQRALHRVVTLLAA---GRPVLTHCFAGKDRTGFVVALVLEAVGLD 181
YR F G+ A +R + AA G P+L HC AGKDRTG+ LVL +G D
Sbjct 126 -----YRSF-VSTGSAHAAYRTLLTEAADPDGGPLLFHCTAGKDRTGWGATLVLSLLGAD 179
Query 182 RDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKA----RLSDGVLGVRAE 237
D ++A+YL N +V + AP + FT A ++ ++GV
Sbjct 180 DDTLMAEYLSVNPAVKE---------------AFAPLIEGFTAAGGDPEIALALIGVFPS 224
Query 238 YLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
YL A + YGS+ Y+ + G+S+ TV +R L+
Sbjct 225 YLEAGLDEVRVRYGSMEKYVHEGLGVSEETVAALRAKLI 263
>gi|269795766|ref|YP_003315221.1| protein tyrosine/serine phosphatase [Sanguibacter keddieii DSM
10542]
gi|269097951|gb|ACZ22387.1| protein tyrosine/serine phosphatase [Sanguibacter keddieii DSM
10542]
Length=315
Score = 100 bits (249), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 93/274 (34%), Positives = 119/274 (44%), Gaps = 44/274 (16%)
Query 5 ELPGAWNFRDVADTA----------TALRPGRLFRSSELSRLDDAGRATLRRLGITDVAD 54
++PG WN RDV + LRPG L RS+ LSRLD AG + LG+T V D
Sbjct 42 DVPGTWNVRDVGASGADGGARLRPGVLLRPGVLLRSASLSRLDPAGVDAVADLGVTAVLD 101
Query 55 LRSSREVARRGPGRVPDGIDVHLLPF----PDLADDDADDSA-----PHETAFKRLLTND 105
LR E+AR G R+P G LPF P D +D S A + L
Sbjct 102 LRGDDEIARDGADRLPPGARQVRLPFGGTSPSPGADTSDASGDGGAVADPLALVKQLVGA 161
Query 106 GSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGK 164
G +G S M Y F T A A+ + +A + VL HC AGK
Sbjct 162 GDPAAAGRS----------VMLRLYAGFATDPAAHAAVAGALRTIADEQGAVLVHCSAGK 211
Query 165 DRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTK 224
DRTG+VVA+V G+ + ++A+YLRS P+V
Sbjct 212 DRTGWVVAVVQLLCGVAPEDVMAEYLRSA-------------ASATTLAATLPDVPGLDP 258
Query 225 ARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLR 258
A D V VR EYL A ++E YGS+ GY R
Sbjct 259 A-FWDAVTTVRPEYLETALHAVEEAYGSVEGYAR 291
>gi|157692558|ref|YP_001487020.1| protein-tyrosine-phosphatase [Bacillus pumilus SAFR-032]
gi|157681316|gb|ABV62460.1| possible protein-tyrosine-phosphatase [Bacillus pumilus SAFR-032]
Length=268
Score = 100 bits (248), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 80/272 (30%), Positives = 128/272 (48%), Gaps = 35/272 (12%)
Query 11 NFRDVADTAT----ALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGP 66
NFR+V T +R G ++RS++LS L T LG+ V DLR++ E P
Sbjct 13 NFREVGGLQTTDEMVIREGMIYRSADLSHLTKQDIETFSTLGVQTVCDLRTASERKSHPP 72
Query 67 GRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYM 126
VH+ PD P + R+L +G + T M
Sbjct 73 KIKEHDKIVHIPMHPD-------SKMPSKWVMFRMLVAEGKSF-----------TFTPIM 114
Query 127 TDEYRQFPTRNGAQRALHRVVTLLA--AGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDV 184
D Y+ T + + ++ LL+ + P++ HC +GKDRTGF+ AL+ A G+
Sbjct 115 KDLYQSMLTERKEE--IQQLFKLLSDKSNYPLMLHCTSGKDRTGFLSALIQLAAGVPVSA 172
Query 185 IVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQ 244
++++Y+RSN+ V L R QQRF ++ + +K ++ +LGV+ +YL
Sbjct 173 VLSEYMRSNEGVKMLVRR-----QQRFVRMMS--LYRVSKQQI-QPLLGVQQDYLEDVLN 224
Query 245 TIDETYGSLGGYLRDAG-ISQATVNRMRGVLL 275
+ ETYGS YL +A I +A + M+ +LL
Sbjct 225 EMMETYGSAERYLIEACDIPEAQLKDMKNILL 256
>gi|297190545|ref|ZP_06907943.1| protein tyrosine phosphatase [Streptomyces pristinaespiralis
ATCC 25486]
gi|297150529|gb|EDY61766.2| protein tyrosine phosphatase [Streptomyces pristinaespiralis
ATCC 25486]
Length=290
Score = 100 bits (248), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 91/260 (35%), Positives = 125/260 (49%), Gaps = 28/260 (10%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL G NFRDV T +RPGRLFRS L+ + A L LG+ + D R++ +
Sbjct 35 ELTGVRNFRDVGGLPTTDGRTVRPGRLFRSGHLAHATASDAAFLSALGLHTIFDFRNAAD 94
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
GP G+ LP D AD F +++ DG N + +S +
Sbjct 95 QRLEGPDIDLPGVRNVNLPLSDPADG---------AEFWKMV-RDG-NLDELKSILADGK 143
Query 121 AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR-PVLTHCFAGKDRTGFVVALVLEAVG 179
A R M YR A+ + RV+ LA P L HC AGKDR G +A+ L AVG
Sbjct 144 GAGR-MIASYRMIIKERTAEHS--RVLHALAEDSVPALMHCAAGKDRAGLSIAVSLLAVG 200
Query 180 LDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYL 239
++RD I ADYL+SND P R ++ ++PEV+ L + RAEYL
Sbjct 201 VERDAIEADYLKSND--PHRRYKVRR--SGNGPDAMSPEVM-----ELLSPLFDARAEYL 251
Query 240 AAARQTIDETYGSLGGYLRD 259
AAA + I+E +G+ YL +
Sbjct 252 AAAFEAIEENWGTTERYLTE 271
>gi|299748023|ref|XP_001837406.2| hypothetical protein CC1G_01318 [Coprinopsis cinerea okayama7#130]
gi|298407783|gb|EAU84322.2| hypothetical protein CC1G_01318 [Coprinopsis cinerea okayama7#130]
Length=281
Score = 99.8 bits (247), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 84/278 (31%), Positives = 120/278 (44%), Gaps = 36/278 (12%)
Query 6 LPGAWNFRDVADTATALRPGR------LFRSSELSRLDDAGRATLRRLGITDVADLRSSR 59
+PG NFRD+ + PG+ LFRS+ELS + D G+A L+ LG+T V DLRS
Sbjct 26 VPGVINFRDLGSYPSTTHPGKVTKPKLLFRSAELSGITDEGKAKLKELGVTQVYDLRSDT 85
Query 60 EVARRG-PGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSI 118
E+ + P DGI H +P A D +P A + L G E I
Sbjct 86 EIKKYNTPSPEIDGIHFHHIPVFQTA-----DYSPEMMAKRYQLYASGKTEAFVELYSQI 140
Query 119 NDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAV 178
D R R + + HC AGKDRTG + AL+L+
Sbjct 141 LDHGGHSFGAVLRHIRDR---------------SSEGCIFHCTAGKDRTGVLAALILKLA 185
Query 179 GLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEY 238
G++ D++ DY + R EMI +R E P + +A L+ + R E
Sbjct 186 GVEDDLVAQDYALTRVG----REPAREMIMKRLAKE--PLFASNNEAALN--MFTCRHET 237
Query 239 LAAARQTIDETYGSLGGYL-RDAGISQATVNRMRGVLL 275
+ A + I+E YG Y+ R G+S + +R LL
Sbjct 238 MMAVLKHIEERYGGAENYIKRYVGLSDEELETVRNNLL 275
>gi|302381765|ref|YP_003817588.1| protein tyrosine/serine phosphatase [Brevundimonas subvibrioides
ATCC 15264]
gi|302192393|gb|ADK99964.1| protein tyrosine/serine phosphatase [Brevundimonas subvibrioides
ATCC 15264]
Length=259
Score = 99.8 bits (247), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 97/276 (36%), Positives = 124/276 (45%), Gaps = 39/276 (14%)
Query 11 NFRDVA--DTAT--ALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGP 66
NFRD DTA AL+ GRLFRS+ + + DA L L I V DLR E RR P
Sbjct 13 NFRDYGGYDTAAGRALKAGRLFRSAHQASVTDADLERLAALDIGTVIDLRRPVE-RRRQP 71
Query 67 GRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYM 126
+ P G ++ +D D APH T K ++ D+ R+M
Sbjct 72 SKRPAGFSGQVIE----SDLDEAGEAPHITFLK--------------TADLTPDSGRRFM 113
Query 127 TDEYRQFPTRNGAQRALHRVVTLLA-AGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVI 185
TD YRQ P R L RPVL HC AGKDRTG + AL +G+ RD +
Sbjct 114 TDTYRQLPFAPAHLDLFARYFRALGETDRPVLIHCAAGKDRTGMLAALTHHLLGVGRDDL 173
Query 186 VADYLRSNDSVPQLRARISEMIQQ----RFDTELAPEVVTFTKARLSDGVLGVRAEYLAA 241
V DYL +N +V L R + +Q T VV F +GV YL A
Sbjct 174 VDDYLLTNTAV-DLAGRAPAIAEQLKAITGRTASHDAVVAF---------MGVEEAYLDA 223
Query 242 ARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLLG 276
A I+ +GS+ GYL A G+ A +R+ L G
Sbjct 224 AIAAIEARHGSIDGYLEQALGVDTALRDRITERLAG 259
>gi|58336494|ref|YP_193079.1| protein tyrosine phosphatase [Lactobacillus acidophilus NCFM]
gi|227903047|ref|ZP_04020852.1| protein tyrosine phosphatase [Lactobacillus acidophilus ATCC
4796]
gi|58253811|gb|AAV42048.1| protein tyrosine phosphatase [Lactobacillus acidophilus NCFM]
gi|227869180|gb|EEJ76601.1| protein tyrosine phosphatase [Lactobacillus acidophilus ATCC
4796]
Length=267
Score = 99.8 bits (247), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 81/284 (29%), Positives = 124/284 (44%), Gaps = 54/284 (19%)
Query 11 NFRDV----ADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGP 66
NFR++ ++ ++ +L R+ L+ L + L G+ D RS EV R+ P
Sbjct 17 NFRELGGYETNSGKKIKMHKLLRTGNLADLSPFDKQFLTDYGVKYDVDFRSKEEVERQ-P 75
Query 67 GRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATR-- 124
RVPDG++ P F LTN SS+SIND T+
Sbjct 76 DRVPDGVEYIYDP-----------------VFSEDLTN---------SSKSINDLNTQAS 109
Query 125 --------YMTDEYRQFPTRNGAQRALHRVVTLL----AAGRPVLTHCFAGKDRTGFVVA 172
+M Y AQ+A + +L G V+ HC AGKDRTGF
Sbjct 110 DDADFGFNHMHYAYEDMIESESAQKAYRKFFDVLLKNDVEGESVIFHCTAGKDRTGFGAL 169
Query 173 LVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVL 232
L+L A+G+ + I DYL +N + + + E +Q E + + +
Sbjct 170 LILSALGVPFNTIKKDYLLTNITTKEFVESMVEHARQNGRNENVLQSIR--------DIQ 221
Query 233 GVRAEYLAAARQTIDETYGSLGGYLRD-AGISQATVNRMRGVLL 275
VRAEY+ A + I++ YGS+ YLRD +S A + ++R + L
Sbjct 222 SVRAEYIDHAVKIINDDYGSIHNYLRDMMKLSSADIMKLRNIYL 265
>gi|262200721|ref|YP_003271929.1| protein tyrosine/serine phosphatase [Gordonia bronchialis DSM
43247]
gi|262084068|gb|ACY20036.1| protein tyrosine/serine phosphatase [Gordonia bronchialis DSM
43247]
Length=270
Score = 99.4 bits (246), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 93/281 (34%), Positives = 125/281 (45%), Gaps = 34/281 (12%)
Query 5 ELPGAWNFRDVADTAT----ALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
+L NFRDV T + GRLFRS+ L + D ATL LG+ V DLRS E
Sbjct 13 DLTAVANFRDVGGMTTHDGRTVATGRLFRSAALGKASDDDIATLAGLGLRTVVDLRSVAE 72
Query 61 VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND 120
+ D V L D+ D SAP + +L+ N E+ + ND
Sbjct 73 ADAAPDPTIGDARGVLL----DVLADAERISAPAD--LDKLIANP-------EAVAAAND 119
Query 121 -----AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVL 175
+ +M YR A+RA T L G P L HC AGKDRTG+ A L
Sbjct 120 RLEQGSGVEHMIGAYRGLVNLPSAKRAYREFFTGLLDGVPTLFHCTAGKDRTGWAAASFL 179
Query 176 EAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVR 235
+G+DRD + +DYLR+ND A + + + P+++ +LGV
Sbjct 180 TLMGVDRDDVYSDYLRTNDLFLPAMAHVFDAFEAAGGD---PDLLR--------PLLGVS 228
Query 236 AEYLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
A YL A + YGS+G Y +A GIS +RMR L
Sbjct 229 ASYLNVAFDEVAIQYGSIGDYFAEALGISADEQDRMREQFL 269
>gi|315504715|ref|YP_004083602.1| protein tyrosine/serine phosphatase [Micromonospora sp. L5]
gi|315411334|gb|ADU09451.1| protein tyrosine/serine phosphatase [Micromonospora sp. L5]
Length=265
Score = 99.4 bits (246), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 96/280 (35%), Positives = 131/280 (47%), Gaps = 31/280 (11%)
Query 5 ELPGAWNFRDVADTATA----LRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE 60
EL GA N RD+ T +R GRL R+ L RL D L +LG V DLR E
Sbjct 7 ELVGAPNARDLGGLPTTDGRRVRAGRLIRTPALGRLTDEDLPVLGKLGPACVVDLRDVHE 66
Query 61 VARRGPGR-VPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIN 119
A P R V + VHL + D + P T +L + + + + +
Sbjct 67 QAVAPPDRLVGEPRTVHLPVY--------DAAHPVFTYVSAVLQGHDLDAYAALAREGMP 118
Query 120 DAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGR--PVLTHCFAGKDRTGFVVALVLEA 177
A MT YR F T A+ V L A G P+L HC AGKDRTG++ ++L A
Sbjct 119 GA----MTAIYRWFVTGESARAGFGAAVRLAAEGANLPLLFHCSAGKDRTGWLSVVLLTA 174
Query 178 VGLDRDVIVADYLRSNDSVPQLR-ARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRA 236
+G++ + I ADYL N+ LR +S MIQ+R D + A ++ +L VR
Sbjct 175 LGVEDEAIRADYLVHNELTESLREVLLSAMIQRRPDLDPA----------VARPLLEVRP 224
Query 237 EYLAAARQTIDETYGSLGGYLRDA-GISQATVNRMRGVLL 275
EYL AA + +GS YLRD G++ A +R LL
Sbjct 225 EYLDAAYDEVRRAHGSFDAYLRDGLGVTDADRAALRERLL 264
Lambda K H
0.319 0.136 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 435544382258
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40