BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0158 Length=214 Score E Sequences producing significant alignments: (Bits) Value gi|15607300|ref|NP_214672.1| TetR family transcriptional regulat... 441 3e-122 gi|339630240|ref|YP_004721882.1| TetR family transcriptional reg... 438 3e-121 gi|254366610|ref|ZP_04982654.1| hypothetical transcriptional reg... 437 4e-121 gi|240168168|ref|ZP_04746827.1| putative transcriptional regulat... 405 2e-111 gi|342859409|ref|ZP_08716063.1| putative transcriptional regulat... 404 4e-111 gi|254822348|ref|ZP_05227349.1| putative transcriptional regulat... 401 3e-110 gi|118619796|ref|YP_908128.1| TetR family transcriptional regula... 394 3e-108 gi|296167349|ref|ZP_06849751.1| TetR family transcriptional regu... 385 2e-105 gi|41409673|ref|NP_962509.1| hypothetical protein MAP3575 [Mycob... 385 2e-105 gi|333988739|ref|YP_004521353.1| TetR family transcriptional reg... 382 2e-104 gi|120401154|ref|YP_950983.1| TetR family transcriptional regula... 341 4e-92 gi|108797089|ref|YP_637286.1| TetR family transcriptional regula... 336 2e-90 gi|315441798|ref|YP_004074677.1| TetR family transcriptional reg... 333 8e-90 gi|145221314|ref|YP_001131992.1| TetR family transcriptional reg... 327 6e-88 gi|118472085|ref|YP_884536.1| transcriptional regulatory protein... 324 6e-87 gi|169631648|ref|YP_001705297.1| TetR family transcriptional reg... 303 8e-81 gi|138894563|ref|YP_001125016.1| TetR/AcrR family transcriptiona... 105 3e-21 gi|319652844|ref|ZP_08006950.1| transcriptional regulator protei... 105 3e-21 gi|295704441|ref|YP_003597516.1| TetR family transcriptional reg... 105 6e-21 gi|345444743|gb|AEN89760.1| TetR/AcrR family transcriptional reg... 102 4e-20 gi|294499113|ref|YP_003562813.1| tetR family transcriptional reg... 101 8e-20 gi|56419566|ref|YP_146884.1| TetR/AcrR family transcriptional re... 98.2 7e-19 gi|336236240|ref|YP_004588856.1| TetR family transcriptional reg... 97.8 9e-19 gi|312111856|ref|YP_003990172.1| TetR family transcriptional reg... 96.7 2e-18 gi|334140799|ref|YP_004534005.1| TetR/AcrR family transcriptiona... 95.9 3e-18 gi|294010386|ref|YP_003543846.1| TetR-family transcriptional reg... 95.9 3e-18 gi|317122942|ref|YP_004102945.1| TetR family transcriptional reg... 95.5 4e-18 gi|94497649|ref|ZP_01304217.1| possible transcriptional regulato... 94.4 1e-17 gi|313903296|ref|ZP_07836688.1| transcriptional regulator, TetR ... 93.2 2e-17 gi|328950874|ref|YP_004368209.1| regulatory protein TetR [Marini... 92.8 3e-17 gi|297530801|ref|YP_003672076.1| TetR family transcriptional reg... 92.4 4e-17 gi|331695899|ref|YP_004332138.1| TetR family transcriptional reg... 92.0 5e-17 gi|261419228|ref|YP_003252910.1| TetR family transcriptional reg... 90.9 1e-16 gi|317126243|ref|YP_004100355.1| TetR transcriptional regulator ... 90.5 1e-16 gi|317404434|gb|EFV84850.1| TetR family Transcriptional regulato... 90.5 1e-16 gi|340355506|ref|ZP_08678190.1| transcriptional regulator [Sporo... 90.1 2e-16 gi|89099724|ref|ZP_01172597.1| transcriptional regulator (TetR/A... 90.1 2e-16 gi|205375483|ref|ZP_03228271.1| TetR/AcrR family transcriptional... 89.4 3e-16 gi|154247994|ref|YP_001418952.1| TetR family transcriptional reg... 89.4 3e-16 gi|229542050|ref|ZP_04431110.1| transcriptional regulator, TetR ... 89.0 4e-16 gi|302188049|ref|ZP_07264722.1| TetR family transcriptional regu... 89.0 4e-16 gi|331695917|ref|YP_004332156.1| TetR family transcriptional reg... 89.0 4e-16 gi|326384056|ref|ZP_08205739.1| regulatory protein TetR [Gordoni... 88.6 5e-16 gi|317121320|ref|YP_004101323.1| regulatory protein TetR [Therma... 88.6 6e-16 gi|295694802|ref|YP_003588040.1| TetR family transcriptional reg... 88.6 6e-16 gi|288555718|ref|YP_003427653.1| TetR/AcrR family transcriptiona... 88.2 6e-16 gi|226355062|ref|YP_002784802.1| TetR family transcriptional reg... 88.2 7e-16 gi|311106114|ref|YP_003978967.1| TetR family transcriptional reg... 88.2 7e-16 gi|325002291|ref|ZP_08123403.1| TetR family transcriptional regu... 88.2 8e-16 gi|56420194|ref|YP_147512.1| TetR/AcrR family transcriptional re... 86.7 2e-15 >gi|15607300|ref|NP_214672.1| TetR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15839538|ref|NP_334575.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31791336|ref|NP_853829.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97] 76 more sequence titles Length=214 Score = 441 bits (1135), Expect = 3e-122, Method: Compositional matrix adjust. Identities = 214/214 (100%), Positives = 214/214 (100%), Gaps = 0/214 (0%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF Sbjct 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS Sbjct 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT Sbjct 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET 214 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET Sbjct 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET 214 >gi|339630240|ref|YP_004721882.1| TetR family transcriptional regulator [Mycobacterium africanum GM041182] gi|339329596|emb|CCC25232.1| putative transcriptional regulatory protein (possibly TETR-family) [Mycobacterium africanum GM041182] Length=214 Score = 438 bits (1126), Expect = 3e-121, Method: Compositional matrix adjust. Identities = 213/214 (99%), Positives = 213/214 (99%), Gaps = 0/214 (0%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF Sbjct 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASN ERAAVYFQEQPYITEWFTS Sbjct 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNLERAAVYFQEQPYITEWFTS 120 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT Sbjct 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET 214 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET Sbjct 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET 214 >gi|254366610|ref|ZP_04982654.1| hypothetical transcriptional regulatory protein (possibly tetR-family) [Mycobacterium tuberculosis str. Haarlem] gi|134152122|gb|EBA44167.1| hypothetical transcriptional regulatory protein (possibly tetR-family) [Mycobacterium tuberculosis str. Haarlem] Length=214 Score = 437 bits (1124), Expect = 4e-121, Method: Compositional matrix adjust. Identities = 212/214 (99%), Positives = 212/214 (99%), Gaps = 0/214 (0%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF Sbjct 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS Sbjct 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQVAEVREKEQQVYEHVHGLIDRGIAS EFYECDSHVVALGYIGMTLGSYRWLRPSGRRT Sbjct 121 EQVAEVREKEQQVYEHVHGLIDRGIASSEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET 214 AKEIAAEFSTALLRGLIRDESIRNQSPLGTR ET Sbjct 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRNET 214 >gi|240168168|ref|ZP_04746827.1| putative transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=207 Score = 405 bits (1041), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 199/209 (96%), Positives = 201/209 (97%), Gaps = 3/209 (1%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 MPS+ NGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASK+LILF Sbjct 1 MPSE---NGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKALILF 57 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLT IA NPERAAVYFQEQPYITEWFTS Sbjct 58 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTGIARNPERAAVYFQEQPYITEWFTS 117 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQVAEVREKE QVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT Sbjct 118 EQVAEVREKEAQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 177 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLG 209 AKEIAAEFSTALLRGLIRDESIR SPLG Sbjct 178 AKEIAAEFSTALLRGLIRDESIRRNSPLG 206 >gi|342859409|ref|ZP_08716063.1| putative transcriptional regulatory protein [Mycobacterium colombiense CECT 3035] gi|342133650|gb|EGT86853.1| putative transcriptional regulatory protein [Mycobacterium colombiense CECT 3035] Length=211 Score = 404 bits (1039), Expect = 4e-111, Method: Compositional matrix adjust. Identities = 196/210 (94%), Positives = 204/210 (98%), Gaps = 1/210 (0%) Query 1 MPSDT-SPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL 59 MPSD+ +PNGL+RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL Sbjct 1 MPSDSITPNGLTRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL 60 Query 60 FDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFT 119 +DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLT IAS+PERAAVYFQE PYITEWFT Sbjct 61 YDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTGIASDPERAAVYFQEAPYITEWFT 120 Query 120 SEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRR 179 SEQVAEVREKE QVY+HVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRR Sbjct 121 SEQVAEVREKETQVYQHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRR 180 Query 180 TAKEIAAEFSTALLRGLIRDESIRNQSPLG 209 +AKEIAAEFSTALLRGLIRDE+IR SPLG Sbjct 181 SAKEIAAEFSTALLRGLIRDEAIRTTSPLG 210 >gi|254822348|ref|ZP_05227349.1| putative transcriptional regulatory protein [Mycobacterium intracellulare ATCC 13950] Length=211 Score = 401 bits (1031), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 194/210 (93%), Positives = 203/210 (97%), Gaps = 1/210 (0%) Query 1 MPSDT-SPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL 59 MP+D+ +PNG +RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL Sbjct 1 MPTDSVTPNGQTRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL 60 Query 60 FDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFT 119 FDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLT IAS+PERAAVYFQEQPYITEWFT Sbjct 61 FDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTGIASDPERAAVYFQEQPYITEWFT 120 Query 120 SEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRR 179 SEQVAEVREKE QVY HVHGLIDRGIASGEFY+CDSHV+ALGYIGMTLGSYRWLRPSGRR Sbjct 121 SEQVAEVREKEAQVYHHVHGLIDRGIASGEFYQCDSHVLALGYIGMTLGSYRWLRPSGRR 180 Query 180 TAKEIAAEFSTALLRGLIRDESIRNQSPLG 209 +AKEIAAEFSTALLRGLIRDE+IR SPLG Sbjct 181 SAKEIAAEFSTALLRGLIRDEAIRTTSPLG 210 >gi|118619796|ref|YP_908128.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|183980412|ref|YP_001848703.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|118571906|gb|ABL06657.1| transcriptional regulatory protein (possibly TetR-family) [Mycobacterium ulcerans Agy99] gi|183173738|gb|ACC38848.1| transcriptional regulatory protein (possibly TetR-family) [Mycobacterium marinum M] Length=207 Score = 394 bits (1013), Expect = 3e-108, Method: Compositional matrix adjust. Identities = 193/210 (92%), Positives = 199/210 (95%), Gaps = 3/210 (1%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 MPS+T GLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF Sbjct 1 MPSET---GLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 57 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIYRQAAEGTL A+H +PSWTAREALYQYTVRLLT IA NPERAAVYFQEQPYI EWFT Sbjct 58 DIYRQAAEGTLGALHAEPSWTAREALYQYTVRLLTGIADNPERAAVYFQEQPYIAEWFTP 117 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQVAEVREKE QV+EHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRP GRRT Sbjct 118 EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPHGRRT 177 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGT 210 A+EIAAEFSTALLRGLIRDESIRNQSPLG+ Sbjct 178 AREIAAEFSTALLRGLIRDESIRNQSPLGS 207 >gi|296167349|ref|ZP_06849751.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897293|gb|EFG76897.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=207 Score = 385 bits (990), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 187/209 (90%), Positives = 196/209 (94%), Gaps = 3/209 (1%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 MPS+ NG +RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL+ Sbjct 1 MPSE---NGRTRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILY 57 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIY+QAAEGTLAAVHDDPSWTAREALYQYTVRLLT IA+NPERAAVYFQE PYI EWFT Sbjct 58 DIYQQAAEGTLAAVHDDPSWTAREALYQYTVRLLTGIAANPERAAVYFQEAPYIAEWFTE 117 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQVA VREKE QVYEHVHGLIDRGIASGEFY+CDSHV+ALGYIGMTLG+YRWLRPSGRR+ Sbjct 118 EQVAAVREKETQVYEHVHGLIDRGIASGEFYQCDSHVLALGYIGMTLGAYRWLRPSGRRS 177 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLG 209 AKEIAAEFSTALLRGLIRDE IR SPLG Sbjct 178 AKEIAAEFSTALLRGLIRDEGIRTSSPLG 206 >gi|41409673|ref|NP_962509.1| hypothetical protein MAP3575 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118463644|ref|YP_884255.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777480|ref|ZP_05218996.1| transcriptional regulator, TetR family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|41398505|gb|AAS06125.1| hypothetical protein MAP_3575 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118164931|gb|ABK65828.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] gi|336459887|gb|EGO38799.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=211 Score = 385 bits (989), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 188/210 (90%), Positives = 197/210 (94%), Gaps = 1/210 (0%) Query 1 MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL 59 MP+D+S PNG +RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL Sbjct 1 MPADSSTPNGQTRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL 60 Query 60 FDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFT 119 +DIY+QAAE TLAAVHDDPS TAREALYQYTVRLL IA+NPE AAVYFQEQPYITEWFT Sbjct 61 YDIYQQAAERTLAAVHDDPSMTAREALYQYTVRLLDQIAANPEGAAVYFQEQPYITEWFT 120 Query 120 SEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRR 179 EQVA VREKE QVYEHVHGLIDRGIASGEFYECDSHV+ALGYIGMTLG+YRWLRPSGRR Sbjct 121 KEQVAAVREKETQVYEHVHGLIDRGIASGEFYECDSHVLALGYIGMTLGAYRWLRPSGRR 180 Query 180 TAKEIAAEFSTALLRGLIRDESIRNQSPLG 209 +AKEIAAEFSTALLRGLIRDE IR SPLG Sbjct 181 SAKEIAAEFSTALLRGLIRDEEIRTTSPLG 210 >gi|333988739|ref|YP_004521353.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333484707|gb|AEF34099.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] Length=212 Score = 382 bits (981), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 185/212 (88%), Positives = 198/212 (94%), Gaps = 2/212 (0%) Query 1 MPSD--TSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLI 58 MP+D +S G SRREELLAVATKLFAARGYHGTRMDDVADV+GLNKATVYHYYASKSLI Sbjct 1 MPNDKGSSAQGPSRREELLAVATKLFAARGYHGTRMDDVADVVGLNKATVYHYYASKSLI 60 Query 59 LFDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWF 118 L+DIY+QAAE TLAAVHDDP+WTAREALYQYTVRLL IA NPE AAVYFQEQPYITEWF Sbjct 61 LYDIYQQAAERTLAAVHDDPTWTAREALYQYTVRLLDQIAVNPEGAAVYFQEQPYITEWF 120 Query 119 TSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGR 178 T EQVAEVREKE QVYEHVHGLIDRGIASGEFY+CDSHV+ALGYIGMTLG+YRWLRPSGR Sbjct 121 TDEQVAEVREKEAQVYEHVHGLIDRGIASGEFYQCDSHVLALGYIGMTLGAYRWLRPSGR 180 Query 179 RTAKEIAAEFSTALLRGLIRDESIRNQSPLGT 210 R+AKEIAAEFSTALLRGLIRDE++R +SPLG Sbjct 181 RSAKEIAAEFSTALLRGLIRDETVRVESPLGV 212 >gi|120401154|ref|YP_950983.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119953972|gb|ABM10977.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=224 Score = 341 bits (875), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 162/207 (79%), Positives = 184/207 (89%), Gaps = 0/207 (0%) Query 3 SDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDI 62 S+++ NG+SRREELLAVATKLFAARGYHGTRMDDVAD +GLNKATVYHYYASKSLIL+DI Sbjct 2 SESTTNGMSRREELLAVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDI 61 Query 63 YRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQ 122 Y+ AA+ T+ A+HDDP+ TARE +Y +T RLL IA++ ERAAVYFQE PYITEWFT EQ Sbjct 62 YKGAADFTVDALHDDPTATARETIYHFTRRLLVGIANDIERAAVYFQEGPYITEWFTEEQ 121 Query 123 VAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAK 182 V +REKE QVYEHV +IDRGIASGEFY+CDSHV+ALGYIGMTLGSYRWLRP GRRTA+ Sbjct 122 VEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQ 181 Query 183 EIAAEFSTALLRGLIRDESIRNQSPLG 209 EIA EFSTALLRGLIRDE++R SPLG Sbjct 182 EIAVEFSTALLRGLIRDETVRTLSPLG 208 >gi|108797089|ref|YP_637286.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119866174|ref|YP_936126.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|126432711|ref|YP_001068402.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|108767508|gb|ABG06230.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119692263|gb|ABL89336.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] gi|126232511|gb|ABN95911.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=219 Score = 336 bits (861), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 159/214 (75%), Positives = 184/214 (86%), Gaps = 0/214 (0%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 M ++ SPNG +RR+ELL VATKLFAARGYHGTRMDDVAD +GLNKATVYHYYASKSLIL+ Sbjct 1 MSAEASPNGSTRRDELLRVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILY 60 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 DIY+ AA+ T+ A+HDDP+ +ARE +Y +T RLL IA++ ERAAVYFQE PYI EWFT Sbjct 61 DIYKGAADFTVDALHDDPTASARETIYHFTRRLLVGIANDIERAAVYFQEGPYIGEWFTE 120 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 EQV +REKE QVYEHV +IDRGIASGEFY+CDSHV+ALGYIGMTLG+YRWLRP GRRT Sbjct 121 EQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMTLGAYRWLRPQGRRT 180 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET 214 A+EIA EFSTALLRGLIRDE++R +SPLG T Sbjct 181 AQEIAEEFSTALLRGLIRDEAVRTESPLGVDVRT 214 >gi|315441798|ref|YP_004074677.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315260101|gb|ADT96842.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=222 Score = 333 bits (855), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 159/205 (78%), Positives = 180/205 (88%), Gaps = 0/205 (0%) Query 6 SPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQ 65 S NG+SRREELLAVATKLFAARGYHGTRMDDVAD +GLNKATVYHYYASKSLIL+DIY+ Sbjct 10 STNGMSRREELLAVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKG 69 Query 66 AAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAE 125 AA+ T+ A+HDDP+ +ARE +Y +T RLL IAS+ ERAAVYFQE PYI+EWFT EQV Sbjct 70 AADFTVDALHDDPTASARETIYHFTRRLLVGIASDIERAAVYFQEGPYISEWFTEEQVDY 129 Query 126 VREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIA 185 +REKE QVYEHV +IDRGIASGEF +CDSHV+ALGYIGMTLGSYRWLRP GRRTA+EIA Sbjct 130 IREKEAQVYEHVRDVIDRGIASGEFNDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIA 189 Query 186 AEFSTALLRGLIRDESIRNQSPLGT 210 EFS+ALLRGLIRDE++R SPLG Sbjct 190 VEFSSALLRGLIRDETVRATSPLGV 214 >gi|145221314|ref|YP_001131992.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145213800|gb|ABP43204.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=209 Score = 327 bits (839), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 156/201 (78%), Positives = 177/201 (89%), Gaps = 0/201 (0%) Query 10 LSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEG 69 +SRREELLAVATKLFAARGYHGTRMDDVAD +GLNKATVYHYYASKSLIL+DIY+ AA+ Sbjct 1 MSRREELLAVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADF 60 Query 70 TLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 T+ A+HDDP+ +ARE +Y +T RLL IAS+ ERAAVYFQE PYI+EWFT EQV +REK Sbjct 61 TVDALHDDPTASARETIYHFTRRLLVGIASDIERAAVYFQEGPYISEWFTEEQVDYIREK 120 Query 130 EQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFS 189 E QVYEHV +IDRGIASGEF +CDSHV+ALGYIGMTLGSYRWLRP GRRTA+EIA EFS Sbjct 121 EAQVYEHVRDVIDRGIASGEFNDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVEFS 180 Query 190 TALLRGLIRDESIRNQSPLGT 210 +ALLRGLIRDE++R SPLG Sbjct 181 SALLRGLIRDETVRATSPLGV 201 >gi|118472085|ref|YP_884536.1| transcriptional regulatory protein [Mycobacterium smegmatis str. MC2 155] gi|118173372|gb|ABK74268.1| probable transcriptional regulatory protein [Mycobacterium smegmatis str. MC2 155] Length=219 Score = 324 bits (830), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 153/207 (74%), Positives = 176/207 (86%), Gaps = 0/207 (0%) Query 3 SDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDI 62 + + NG SRREELL VA KLFAARGYHGTRMDDVA+ +GLNKATVYHYYASKSLIL+DI Sbjct 2 TSAANNGTSRREELLNVAAKLFAARGYHGTRMDDVAEAVGLNKATVYHYYASKSLILYDI 61 Query 63 YRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQ 122 Y+ AA+ T+ A+HDDP+ +ARE +Y +T RL+ IA++ ERAAVYFQE PYI EWFT EQ Sbjct 62 YKSAADFTVEALHDDPTSSARETIYHFTRRLMVGIANDLERAAVYFQEGPYIAEWFTEEQ 121 Query 123 VAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAK 182 V +R E QVYEHV +IDRGIASGEFY+CDSHV+ALGYIGM LG+YRWLRP GRRTAK Sbjct 122 VEYIRHSEAQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMVLGAYRWLRPHGRRTAK 181 Query 183 EIAAEFSTALLRGLIRDESIRNQSPLG 209 EIA EFSTALLRGLIRDE+IR +SPLG Sbjct 182 EIAVEFSTALLRGLIRDENIRVESPLG 208 >gi|169631648|ref|YP_001705297.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169243615|emb|CAM64643.1| Probable transcriptional regulator, TetR family [Mycobacterium abscessus] Length=228 Score = 303 bits (777), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 142/203 (70%), Positives = 167/203 (83%), Gaps = 0/203 (0%) Query 12 RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL 71 RREEL+AVA+KLFAARGYHGTRMDD+ADV GLNKATVYHY+ASK+LIL++IY +AAE TL Sbjct 20 RREELVAVASKLFAARGYHGTRMDDIADVAGLNKATVYHYFASKALILYEIYFKAAEETL 79 Query 72 AAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQ 131 A + DDP W+ARE+LYQ T R+L I SN E+ AVYFQE P+++EW + EQVAE+R +E Sbjct 80 ACLQDDPRWSARESLYQCTSRMLALIFSNREQGAVYFQENPFLSEWLSPEQVAEIRTRED 139 Query 132 QVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTA 191 V E V +I+RGIASGEF ECDSHV+ALGYIGM LGSYRWL PSGRR+A+EIA EFST Sbjct 140 MVQERVQNIIERGIASGEFVECDSHVMALGYIGMVLGSYRWLNPSGRRSAQEIAVEFSTT 199 Query 192 LLRGLIRDESIRNQSPLGTRKET 214 LLRGLIRDE+ R PLG T Sbjct 200 LLRGLIRDEATRINDPLGVASAT 222 >gi|138894563|ref|YP_001125016.1| TetR/AcrR family transcriptional regulator [Geobacillus thermodenitrificans NG80-2] gi|196247830|ref|ZP_03146532.1| transcriptional regulator, TetR family [Geobacillus sp. G11MC16] gi|134266076|gb|ABO66271.1| Transcriptional regulator (TetR/AcrR family) [Geobacillus thermodenitrificans NG80-2] gi|196212614|gb|EDY07371.1| transcriptional regulator, TetR family [Geobacillus sp. G11MC16] Length=191 Score = 105 bits (263), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 58/188 (31%), Positives = 98/188 (53%), Gaps = 8/188 (4%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL- 71 RE+++A + +LF G+ T + D+ D +G+ K T Y+Y+ SK +L DI+ + EG L Sbjct 2 REKIIAASIELFEQNGFSETSIQDIVDALGVTKGTFYYYFKSKEELLMDIHLRYIEGLLS 61 Query 72 --AAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 A + +D T RE LY L+ + +A ++F+E +++E E + +V+EK Sbjct 62 EQARIMNDEQRTMREKLYAIVYMLIHNVERQGRQARIFFREMKHLSE----EHLQKVKEK 117 Query 130 EQQVYEHVHGLIDRGIASGEF-YECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 H+ LI+ G+ +GE + + L +G SY W RP G T E+A + Sbjct 118 RDLFRYHLQALIEEGMKTGELRRDLSPSIATLTVLGAANWSYHWFRPDGELTDAEVAKQM 177 Query 189 STALLRGL 196 T L+ G+ Sbjct 178 VTILIEGM 185 >gi|319652844|ref|ZP_08006950.1| transcriptional regulator protein [Bacillus sp. 2_A_57_CT2] gi|317395421|gb|EFV76153.1| transcriptional regulator protein [Bacillus sp. 2_A_57_CT2] Length=187 Score = 105 bits (263), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 56/188 (30%), Positives = 105/188 (56%), Gaps = 8/188 (4%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 +E++ + +LF +G+ T + D+ D IG+ K T Y+Y++SK +L DI+ + + L Sbjct 2 KEKITEKSIRLFDQKGFSETSIQDIVDSIGVTKGTFYYYFSSKEELLMDIHLRYIDDMLD 61 Query 73 AVHD---DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 H+ D S +++E L+ LL+ I + A V+F+E +++ E ++E+ K Sbjct 62 NQHEILGDDSKSSKEKLFAIVQMLLSNIKTQGASAKVFFREMRNLSD----ESLSEIIPK 117 Query 130 EQQVYEHVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 Q ++ LI+ G +GEF +S ++A G +G+T SY+W P G + +E+A F Sbjct 118 RDQFRLNIEKLIEEGKQNGEFRANLNSPIIAFGILGVTNWSYQWFNPDGSISDREVAEIF 177 Query 189 STALLRGL 196 + +L+G+ Sbjct 178 TEMILKGI 185 >gi|295704441|ref|YP_003597516.1| TetR family transcriptional regulator [Bacillus megaterium DSM 319] gi|294802100|gb|ADF39166.1| transcriptional regulator, tetR family protein [Bacillus megaterium DSM 319] Length=187 Score = 105 bits (261), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 56/188 (30%), Positives = 107/188 (57%), Gaps = 8/188 (4%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL- 71 ++ ++ ++ +LFA +G+ T + D+ + + + K T Y+Y+ SK +L DI+ Q E + Sbjct 2 KDLMMELSIQLFAQKGFKETSIQDIVNELNVTKGTFYYYFKSKQELLMDIHLQYIERLIE 61 Query 72 --AAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 A+ D + + E L+ +L+ I RA V+F+E +++E E + ++ K Sbjct 62 NQEAILADKTTSYPEKLHSIIFKLVHDIEKEGLRAKVFFREMRHLSE----EHLEQIIPK 117 Query 130 EQQVYEHVHGLIDRGIASGEF-YECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 + E+V +I++GI +G+F + S +V LG +GMT SY W +P G ++ +E+AA F Sbjct 118 RDRFKENVQEIIEKGIEAGQFRSDLPSDIVTLGILGMTNWSYFWFQPDGEKSDREVAAIF 177 Query 189 STALLRGL 196 L++G+ Sbjct 178 YKMLMKGI 185 >gi|345444743|gb|AEN89760.1| TetR/AcrR family transcriptional regulator [Bacillus megaterium WSH-002] Length=188 Score = 102 bits (254), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 55/185 (30%), Positives = 103/185 (56%), Gaps = 8/185 (4%) Query 16 LLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA--- 72 ++ + +LFA +G+ T + D+ + + + K T Y+Y+ SK +L DI+ Q E + Sbjct 5 MMERSIQLFAQKGFKETSIQDIVNELNVTKGTFYYYFKSKQELLMDIHLQYIERLIENQE 64 Query 73 AVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQ 132 + D + + E L+ +L+ I RA V+F+E +++E E + ++ K + Sbjct 65 TILADKTTSYPEKLHSIIFKLVHDIEKEGLRAKVFFREMRHLSE----EHLEQIIPKRDR 120 Query 133 VYEHVHGLIDRGIASGEF-YECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTA 191 E+V +I++G+ +G+F + S +V LG +GMT SY W +P G +T +E+AA F Sbjct 121 FKENVQEIIEKGMEAGQFRSDLPSDIVTLGILGMTNWSYFWFQPDGEKTDREVAAIFYKM 180 Query 192 LLRGL 196 L++G+ Sbjct 181 LMKGI 185 >gi|294499113|ref|YP_003562813.1| tetR family transcriptional regulator [Bacillus megaterium QM B1551] gi|294349050|gb|ADE69379.1| transcriptional regulator, tetR family protein [Bacillus megaterium QM B1551] Length=188 Score = 101 bits (251), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 55/185 (30%), Positives = 103/185 (56%), Gaps = 8/185 (4%) Query 16 LLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA--- 72 ++ + +LFA +G+ T + D+ + + + K T Y+Y+ SK +L DI+ Q E + Sbjct 5 MMERSIQLFAQKGFKETSIQDIVNELNVTKGTFYYYFKSKQELLMDIHLQYIERLIENQE 64 Query 73 AVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQ 132 + D + + E L+ +L+ I RA V+F+E +++E E + ++ K + Sbjct 65 TILADKTTSYPEKLHSIIFKLVHDIEKEGLRAKVFFREMRHLSE----EHLEQIIPKRDR 120 Query 133 VYEHVHGLIDRGIASGEF-YECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTA 191 E+V +I++GI +G+F + S +V LG +GMT SY W +P G ++ +E+AA F Sbjct 121 FKENVQEIIEKGIEAGQFRSDLPSDIVTLGILGMTNWSYFWFQPDGEKSDREVAAIFYKM 180 Query 192 LLRGL 196 L++G+ Sbjct 181 LVKGI 185 >gi|56419566|ref|YP_146884.1| TetR/AcrR family transcriptional regulator [Geobacillus kaustophilus HTA426] gi|56379408|dbj|BAD75316.1| transcriptional regulator (TetR/AcrR family) [Geobacillus kaustophilus HTA426] Length=194 Score = 98.2 bits (243), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 57/189 (31%), Positives = 94/189 (50%), Gaps = 10/189 (5%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 +E+++A + +LF G+ T + D+ D +G+ K T Y+Y+ SK +L DI+ + EG L Sbjct 2 KEKIMAASIELFEQNGFSETSIQDIVDALGVTKGTFYYYFTSKEELLMDIHLRYIEGLLD 61 Query 73 A---VHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 + D RE LY L+ + A ++F+E +++E E + +V+EK Sbjct 62 EEERIISDKRRPLREKLYDIIFMLIHNVERQGREARIFFREMKHLSE----EHLQKVKEK 117 Query 130 EQQVYEHVHGLIDRGIASGEFYECD--SHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAE 187 + LI+ G+ SGE CD + L +G SY+W RP G T E+A + Sbjct 118 RDLFRYRLQSLIEEGMKSGEL-RCDLSPSIATLTVLGAANWSYQWFRPDGELTDAEVAKQ 176 Query 188 FSTALLRGL 196 LL G+ Sbjct 177 MVEILLDGM 185 >gi|336236240|ref|YP_004588856.1| TetR family transcriptional regulator [Geobacillus thermoglucosidasius C56-YS93] gi|335363095|gb|AEH48775.1| transcriptional regulator, TetR family [Geobacillus thermoglucosidasius C56-YS93] Length=188 Score = 97.8 bits (242), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 58/179 (33%), Positives = 92/179 (52%), Gaps = 10/179 (5%) Query 23 LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL---AAVHDDPS 79 LF G+ T + D+ D +G+ K T Y+Y+ SK +L DI+ + EG L + DP+ Sbjct 7 LFDENGFSETSVQDIVDALGVTKGTFYYYFKSKEELLMDIHLRYIEGLLEKQKKIIGDPA 66 Query 80 WTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHG 139 TA+E + L+ I +A V+F+E ++ E E + ++ EK + Sbjct 67 KTAKEKVLDIVYMLIHNIEKQGRQARVFFREMKHLNE----EHLKKISEKRDMFRYGLQS 122 Query 140 LIDRGIASGEFYECDSH--VVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGL 196 LI++GI +GEF E D H + AL +G SY+W RP G + E+A + LL G+ Sbjct 123 LIEKGIKNGEFRE-DLHPSIAALTVLGAANWSYQWFRPDGELSDFEVAKQMVAILLEGM 180 >gi|312111856|ref|YP_003990172.1| TetR family transcriptional regulator [Geobacillus sp. Y4.1MC1] gi|311216957|gb|ADP75561.1| transcriptional regulator, TetR family [Geobacillus sp. Y4.1MC1] Length=188 Score = 96.7 bits (239), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 57/179 (32%), Positives = 91/179 (51%), Gaps = 10/179 (5%) Query 23 LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL---AAVHDDPS 79 LF G+ T + D+ D +G+ K T Y+Y+ SK +L DI+ + EG L + DP+ Sbjct 7 LFDENGFSETSVQDIVDALGVTKGTFYYYFKSKEELLMDIHLRYIEGLLEKQKKIIGDPA 66 Query 80 WTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHG 139 T +E + L+ I +A V+F+E ++ E E + ++ EK + Sbjct 67 KTVKEKVLDIVYMLIHNIEKQGRQARVFFREMKHLNE----EHLKKISEKRDMFRYGLQS 122 Query 140 LIDRGIASGEFYECDSH--VVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGL 196 LI++GI +GEF E D H + AL +G SY+W RP G + E+A + LL G+ Sbjct 123 LIEKGIKNGEFRE-DLHPSIAALTVLGAANWSYQWFRPDGELSDFEVAKQMVAILLEGM 180 >gi|334140799|ref|YP_004534005.1| TetR/AcrR family transcriptional regulator [Novosphingobium sp. PP1Y] gi|333938829|emb|CCA92187.1| TetR/AcrR family transcriptional regulator [Novosphingobium sp. PP1Y] Length=203 Score = 95.9 bits (237), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 56/189 (30%), Positives = 89/189 (48%), Gaps = 6/189 (3%) Query 12 RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL 71 +R E+L LF GYHG M +AD +GL K T+YHY++SK IL+ I+ + Sbjct 18 KRNEILKHCASLFDKVGYHGASMQMIADEVGLGKPTLYHYFSSKQAILYAIHDAHITALI 77 Query 72 AAVH-DDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKE 130 + DPS L + +L IA +P + + T+ Q E+R + Sbjct 78 DGLDASDPSIEPSRLLRLACIDILREIAEHPGYVRAFMD---HYTD-LEGPQRQEIRSRR 133 Query 131 QQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWL-RPSGRRTAKEIAAEFS 189 Q + + +I RGI S F ECD + G++GM +Y+W + + +R +++A Sbjct 134 QDYFNRIQSIIARGIESKHFIECDPVLTVYGFLGMCNWAYKWYPQVAKKRKPEDVADALC 193 Query 190 TALLRGLIR 198 GL R Sbjct 194 RPFFEGLCR 202 >gi|294010386|ref|YP_003543846.1| TetR-family transcriptional regulator [Sphingobium japonicum UT26S] gi|292673716|dbj|BAI95234.1| TetR-family transcriptional regulator [Sphingobium japonicum UT26S] Length=205 Score = 95.9 bits (237), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 58/191 (31%), Positives = 91/191 (48%), Gaps = 14/191 (7%) Query 12 RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL 71 +R E+L LF GYH M +AD +GL K T+YHY+ SK+ ILF ++ L Sbjct 18 KRNEILRHCATLFDRVGYHKASMQMLADEVGLGKPTLYHYFPSKNAILFAMHDAHMSALL 77 Query 72 AAVH-----DDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEV 126 A + DDP R A + +L IA +P + E + + Sbjct 78 AGLDEEGGSDDPLGRLRAA----CIDILRQIAEHPGYVRAFMDH----YEDLEGKMRDHI 129 Query 127 REKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRP-SGRRTAKEIA 185 R + + V G+I++GIA+G F +CD + LG++GM +Y+W P + RR+ +++A Sbjct 130 RAQRNAYLQRVRGIIEQGIANGHFRQCDPGLTTLGFLGMCNWAYKWYPPLAKRRSPEDVA 189 Query 186 AEFSTALLRGL 196 GL Sbjct 190 DAICKPFFEGL 200 >gi|317122942|ref|YP_004102945.1| TetR family transcriptional regulator [Thermaerobacter marianensis DSM 12885] gi|315592922|gb|ADU52218.1| transcriptional regulator, TetR family [Thermaerobacter marianensis DSM 12885] Length=204 Score = 95.5 bits (236), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 62/196 (32%), Positives = 101/196 (52%), Gaps = 14/196 (7%) Query 7 PNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQA 66 P +RREE+LAVA +LF +GYH T M D+A+ + L + ++Y + SK +LFDI +A Sbjct 2 PRSTARREEILAVAGELFRQKGYHATSMQDIAERLQLQRGSLYAHIDSKEELLFDIVDRA 61 Query 67 AEGTLAAVHDDPSW----TAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEW--FTS 120 A+ LA + + +W TARE L + ++ IA + + A+V+F EW Sbjct 62 ADRFLAGI--EQAWREGRTARERLRRALAAHMSVIAEHRDTASVFFH------EWRFLRD 113 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 + ++ K + L+ G+ GEF D AL + +Y+W P G + Sbjct 114 DLRRRIQAKRDRYEARWRELVADGVQRGEFRPVDPRFAALLALSAVNWAYQWYSPEGPLS 173 Query 181 AKEIAAEFSTALLRGL 196 +E+A F+ +L+GL Sbjct 174 PEEVAGAFADLILQGL 189 >gi|94497649|ref|ZP_01304217.1| possible transcriptional regulator, TetR family protein [Sphingomonas sp. SKA58] gi|94422866|gb|EAT07899.1| possible transcriptional regulator, TetR family protein [Sphingomonas sp. SKA58] Length=205 Score = 94.4 bits (233), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 58/191 (31%), Positives = 91/191 (48%), Gaps = 14/191 (7%) Query 12 RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL 71 +R E+L LF GYH M +AD +GL K T+YHY++SKS ILF ++ L Sbjct 18 KRNEILGHCATLFDRVGYHKASMQMLADEVGLGKPTLYHYFSSKSAILFAMHDAHMSALL 77 Query 72 AAVH-----DDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEV 126 A + DDP L+ V +L IA +P + E + + Sbjct 78 AGLDEERGSDDPL----RRLHAACVDILRQIAEHPGYVRAFMDH----YEDLEGKMREHI 129 Query 127 REKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRP-SGRRTAKEIA 185 R + + V G+I++GIA+G+F CD + L ++GM +Y+W P + RR+ +++A Sbjct 130 RAQRNAYLQRVRGIIEQGIANGQFRACDPGLTTLAFLGMCNWAYKWYPPLAKRRSPEDVA 189 Query 186 AEFSTALLRGL 196 GL Sbjct 190 DAICQPFFEGL 200 >gi|313903296|ref|ZP_07836688.1| transcriptional regulator, TetR family [Thermaerobacter subterraneus DSM 13965] gi|313466384|gb|EFR61906.1| transcriptional regulator, TetR family [Thermaerobacter subterraneus DSM 13965] Length=194 Score = 93.2 bits (230), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 59/190 (32%), Positives = 101/190 (54%), Gaps = 10/190 (5%) Query 11 SRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGT 70 +RREE+L VA +LF +GYH T M D+A+ + L + ++Y + SK +LF+I +AA+ Sbjct 6 ARREEILTVAGELFRQKGYHATSMQDIAERLQLQRGSLYAHIESKEELLFEIVDRAADRF 65 Query 71 LAAVHDDPSW----TAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEV 126 LA + + +W TAR+ L + + IA + + A+V+F E ++ ++ + + Sbjct 66 LAGI--EQAWREGTTARDRLRRALAAHMAVIAEHRDTASVFFHEWRFL----RADLRSRI 119 Query 127 REKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAA 186 + K + LI G+A GEF D AL + +Y+W P G ++AA Sbjct 120 QAKRDRYEARWRELIADGVARGEFRAVDPRFAALLALSAVNWAYQWYSPDGPLAPDDVAA 179 Query 187 EFSTALLRGL 196 F+ +L+GL Sbjct 180 TFAELILKGL 189 >gi|328950874|ref|YP_004368209.1| regulatory protein TetR [Marinithermus hydrothermalis DSM 14884] gi|328451198|gb|AEB12099.1| regulatory protein TetR [Marinithermus hydrothermalis DSM 14884] Length=188 Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 63/190 (34%), Positives = 94/190 (50%), Gaps = 9/190 (4%) Query 10 LSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEG 69 + RR ++L A +LF+ RGYH T M D+A + L ++Y + SK +L++I +AA+ Sbjct 1 MDRRTQILHTAGRLFSQRGYHATSMRDIARALDLQGGSLYTHIESKEEVLWEIVNRAADR 60 Query 70 TLA-AVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEW-FTSEQVAEVR 127 LA A DP RE L LT IA E A V+F EW F S ++ E Sbjct 61 FLAHATSIDPDLPPRERLKALVRGHLTVIAQELEHATVFFH------EWKFLSPELQERI 114 Query 128 EKEQQVYE-HVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAA 186 + + YE H I+ G+ GEF D + AL + +Y+WLRP G + + Sbjct 115 KARRDAYEAHFREAIESGVQRGEFKVEDPKIAALFVLSALNWTYQWLRPEGPLDLEALTE 174 Query 187 EFSTALLRGL 196 ++ +LR L Sbjct 175 RYTALVLRAL 184 >gi|297530801|ref|YP_003672076.1| TetR family transcriptional regulator [Geobacillus sp. C56-T3] gi|297254053|gb|ADI27499.1| transcriptional regulator, TetR family [Geobacillus sp. C56-T3] Length=189 Score = 92.4 bits (228), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 55/185 (30%), Positives = 89/185 (49%), Gaps = 10/185 (5%) Query 17 LAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLAA--- 73 +A + +LF G+ T + D+ D +G+ K T Y+Y+ SK +L DI+ + E L Sbjct 1 MAASIELFEQNGFSETSIQDIVDALGVTKGTFYYYFTSKEELLMDIHLRYIERLLDEEER 60 Query 74 VHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQV 133 + D + RE LY L+ + A ++F+E ++ E E + +V+EK Sbjct 61 IISDKRRSVREKLYDIIFMLIHNVERQGREARIFFREMKHLNE----EHLQKVKEKRDLF 116 Query 134 YEHVHGLIDRGIASGEFYECD--SHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTA 191 + LI+ G+ SGE CD + L +G SY+W RP G T E+A + Sbjct 117 RYRLQSLIEEGMKSGEL-RCDLSPSIATLTVLGAANWSYQWFRPDGELTDAEVAKQMVEI 175 Query 192 LLRGL 196 LL G+ Sbjct 176 LLDGM 180 >gi|331695899|ref|YP_004332138.1| TetR family transcriptional regulator [Pseudonocardia dioxanivorans CB1190] gi|326950588|gb|AEA24285.1| transcriptional regulator, TetR family [Pseudonocardia dioxanivorans CB1190] Length=208 Score = 92.0 bits (227), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 94/200 (47%), Gaps = 20/200 (10%) Query 6 SPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQ 65 +P G +RR E++A A +LF RGYH T MDD+A +G+ K T+YH+ SK+ I+ I+ + Sbjct 4 APQGTARRAEIVAAAARLFDERGYHATSMDDIAAAVGIKKPTLYHHVQSKTQIVIWIHDE 63 Query 66 AAEGTLAAVHDDPSWTAR---------EALYQYTVRLLTAIASNPERAAVYFQEQPYITE 116 VHD + E L + +L + + P VYF+ I Sbjct 64 -------LVHDLTDRLEQRVADKLPRAEILLRVMDDILGLLETRPGHLRVYFEHHREI-- 114 Query 117 WFTSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPS 176 E+ RE + E V LI+ G A+GEF + + + GM +Y+W RP Sbjct 115 --PGEEGRVAREMRDRYTETVRQLIEEGAAAGEFRVENPGLTTFAFFGMCNWAYQWYRPG 172 Query 177 GRRTAKEIAAEFSTALLRGL 196 G T + IA F + G+ Sbjct 173 GPLTHQVIARYFWQIFMSGI 192 >gi|261419228|ref|YP_003252910.1| TetR family transcriptional regulator [Geobacillus sp. Y412MC61] gi|319766044|ref|YP_004131545.1| TetR family transcriptional regulator [Geobacillus sp. Y412MC52] gi|261375685|gb|ACX78428.1| transcriptional regulator, TetR family [Geobacillus sp. Y412MC61] gi|317110910|gb|ADU93402.1| transcriptional regulator, TetR family [Geobacillus sp. Y412MC52] Length=189 Score = 90.9 bits (224), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 54/185 (30%), Positives = 89/185 (49%), Gaps = 10/185 (5%) Query 17 LAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLAA--- 73 +A + +LF G+ T + D+ D +G+ K T Y+Y+ SK +L DI+ + E L Sbjct 1 MAASIELFEQNGFSETSIQDIVDALGVTKGTFYYYFTSKEELLMDIHLRYIERLLDEEER 60 Query 74 VHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQV 133 + D + +E LY L+ + A ++F+E ++ E E + +V+EK Sbjct 61 IISDKRRSVQEKLYDIIFMLIHNVERQGREARIFFREMKHLNE----EHLQKVKEKRDLF 116 Query 134 YEHVHGLIDRGIASGEFYECD--SHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTA 191 + LI+ G+ SGE CD + L +G SY+W RP G T E+A + Sbjct 117 RYRLQSLIEEGMKSGEL-RCDLSPSIATLTVLGAANWSYQWFRPDGELTDAEVAKQMVEI 175 Query 192 LLRGL 196 LL G+ Sbjct 176 LLDGM 180 >gi|317126243|ref|YP_004100355.1| TetR transcriptional regulator [Intrasporangium calvum DSM 43043] gi|315590331|gb|ADU49628.1| transcriptional regulator, TetR family [Intrasporangium calvum DSM 43043] Length=204 Score = 90.5 bits (223), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 56/196 (29%), Positives = 94/196 (48%), Gaps = 6/196 (3%) Query 6 SPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQ 65 S ++RR+E++ A +F ARGY+ MDD+A+ +G+ K T+YHY SK I+ I+ + Sbjct 3 SRKSITRRDEIVKTAAIIFEARGYYNASMDDIAEAMGIRKPTLYHYVESKGQIVAWIHDR 62 Query 66 AAEGTLAAVHD--DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQV 123 +G + ++ + E L + + S+P VYF+ I E + Sbjct 63 LCDGFIDRINQRIEQGMQPTECLVMVMTDIFETLDSSPGHLRVYFEHHREIPE----KCQ 118 Query 124 AEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKE 183 A R K + + V LI G +GEF ++ + GM +Y+W RP G+ + +E Sbjct 119 ATSRAKRDEYFATVRDLIIAGEEAGEFKVENAEMATFALFGMCNWAYQWYRPKGQLSPQE 178 Query 184 IAAEFSTALLRGLIRD 199 I+ F G+ D Sbjct 179 ISQMFWRIFASGIKVD 194 >gi|317404434|gb|EFV84850.1| TetR family Transcriptional regulator [Achromobacter xylosoxidans C54] Length=240 Score = 90.5 bits (223), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 62/206 (31%), Positives = 98/206 (48%), Gaps = 15/206 (7%) Query 8 NGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLIL-------F 60 G + R +L A LF RG GT + D+A+ +GL++ VY+Y+ SK IL Sbjct 11 KGEALRSAILDAAATLFIERGTGGTSIQDIAETLGLSRTAVYYYFKSKDAILRALTEEVL 70 Query 61 DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 + R+ A T+A DP +AL R I S P F+ T Sbjct 71 NTARKLAGETVARADLDPV----QALGALVARHADLILSRP----AEFRVADRTEGDMTP 122 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 +Q A ++ + + E+ +I++G+ G+F D H+ A+ IGM S W +P GR + Sbjct 123 KQRAALQAARRSLLENFSTVIEKGVRDGQFRMVDPHIAAVSLIGMCNWSAWWYKPDGRLS 182 Query 181 AKEIAAEFSTALLRGLIRDESIRNQS 206 E++A + +R L+RDE R +S Sbjct 183 RAEVSAIMADMAVRSLLRDEERRPRS 208 >gi|340355506|ref|ZP_08678190.1| transcriptional regulator [Sporosarcina newyorkensis 2681] gi|339622345|gb|EGQ26868.1| transcriptional regulator [Sporosarcina newyorkensis 2681] Length=188 Score = 90.1 bits (222), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 53/188 (29%), Positives = 94/188 (50%), Gaps = 8/188 (4%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL- 71 +E++ + LF +G+ T + D+ D IG+ K T Y+Y+ SK +L +I+ L Sbjct 2 KEKITQASILLFEQKGFSQTSIQDIVDSIGVTKGTFYYYFTSKEQLLMEIHLDYISDLLN 61 Query 72 --AAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 ++ ++ T +E L + V L+ I V+F+E ++ E E V + ++ Sbjct 62 RQQSIMENEKLTYQEKLEKVIVLLIADIQDKGPSGRVFFREMRHLVE----ENVETIDKQ 117 Query 130 EQQVYEHVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 ++ L+ GI +GEF E + +VA G +GM SY W PSG +A++++ F Sbjct 118 RDLFRLNIEQLVADGIQAGEFRPELRADIVAFGVLGMANYSYNWFNPSGEISAEQLSKLF 177 Query 189 STALLRGL 196 S L G+ Sbjct 178 SMILFDGI 185 >gi|89099724|ref|ZP_01172597.1| transcriptional regulator (TetR/AcrR family) protein [Bacillus sp. NRRL B-14911] gi|89085471|gb|EAR64599.1| transcriptional regulator (TetR/AcrR family) protein [Bacillus sp. NRRL B-14911] Length=187 Score = 90.1 bits (222), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 50/188 (27%), Positives = 98/188 (53%), Gaps = 8/188 (4%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 +E++ + +LF +G+ T + D+ D IG+ K T Y+Y++SK +L DI+ + + L+ Sbjct 2 KEKITEQSIRLFDKKGFSETSIQDIVDSIGVTKGTFYYYFSSKEELLMDIHLRYIDDLLS 61 Query 73 ---AVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 + + + + LY L+ +I + A V+F+E ++E E++ ++ K Sbjct 62 QQEKILKNSNADCKGKLYDVVAMLIGSIENQGASAKVFFREIRNLSE----ERLGQIIPK 117 Query 130 EQQVYEHVHGLIDRGIASGEFYE-CDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 + ++ LI GI +GEF E ++ ++ G +G SY+W P+G E+A F Sbjct 118 RDRFRTNIEALISEGIRNGEFREDLNASIITFGILGAANWSYQWFSPNGSVPDYEVARIF 177 Query 189 STALLRGL 196 + +L G+ Sbjct 178 TDMVLNGI 185 >gi|205375483|ref|ZP_03228271.1| TetR/AcrR family transcriptional regulator [Bacillus coahuilensis m4-4] Length=187 Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 56/188 (30%), Positives = 96/188 (52%), Gaps = 8/188 (4%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 +E++ A +LFA +G+ T + D+ D +G+ K T Y+Y+ SK +L +I+ E L Sbjct 2 KEQMTEKAIELFARKGFKETSIQDIVDSLGVTKGTFYYYFTSKDSLLMEIHTAYIEKLLI 61 Query 73 ---AVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 + +D S + +E LY L+ I + + A V+ +E + + E+V +R+K Sbjct 62 QQEQLLEDRSKSVQEKLYSIVYSLIQDIGEHGQSARVFIREMRNLND-NDLEKVIPLRDK 120 Query 130 EQQVYEHVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 E++ LI G+ GEF + +V G +GM SY W + +GR T +E+ F Sbjct 121 ---FRENIEELIQEGVEYGEFRDDLSVDIVTFGILGMANWSYLWYQMNGRMTEEEVTKVF 177 Query 189 STALLRGL 196 +L GL Sbjct 178 MEMILNGL 185 >gi|154247994|ref|YP_001418952.1| TetR family transcriptional regulator [Xanthobacter autotrophicus Py2] gi|154162079|gb|ABS69295.1| transcriptional regulator, TetR family [Xanthobacter autotrophicus Py2] Length=223 Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 61/204 (30%), Positives = 89/204 (44%), Gaps = 23/204 (11%) Query 12 RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL 71 +RE +L A +LF +G+H T +DDVA + + K T+YHY+ SK +LF+ R E Sbjct 30 KREAVLKAAARLFNEKGFHATSLDDVARQLNVTKPTLYHYFRSKDDVLFECCRMGLEMIE 89 Query 72 AAVHDDPSWTA------REALYQY----TVRLLTAIASNPERAAVYFQEQPYITEWFTSE 121 AA P A R + QY T+ +I+ P+ A + E Sbjct 90 AAAATVPGSQASGLERLRALMEQYAEAMTMDFGMSISRTPDTA-------------LSPE 136 Query 122 QVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTA 181 AE+R + Q+ + G+I GI G CD A G W +P G Sbjct 137 NRAELRRLKAQIDRALRGVIQSGIEDGSIAPCDVRTAAFAIAGALNAIAHWYKPDGPLAP 196 Query 182 KEIAAEFSTALLRGLIRDESIRNQ 205 EIA + + L++GL S R Q Sbjct 197 AEIARQTADFLIQGLAPRTSERRQ 220 >gi|229542050|ref|ZP_04431110.1| transcriptional regulator, TetR family [Bacillus coagulans 36D1] gi|229326470|gb|EEN92145.1| transcriptional regulator, TetR family [Bacillus coagulans 36D1] Length=187 Score = 89.0 bits (219), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 53/182 (30%), Positives = 96/182 (53%), Gaps = 11/182 (6%) Query 20 ATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYR----QAAEGTLAAVH 75 + +LF +G+ T + D+ D IG K T Y+Y++SK +L DI+ + E A + Sbjct 9 SIRLFEQKGFTETSIQDIVDSIGATKGTFYYYFSSKEQLLMDIHMDYITKLLEKQKAILS 68 Query 76 DDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYE 135 ++ S A+ L+ + LL +I + +A ++F+E + + E++ + +K + Sbjct 69 ENGSCKAK--LHALVLMLLESIKTEKAKALIFFREIKNL----SGEKLELILQKREAFRL 122 Query 136 HVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLR 194 V LI GI GEF D+++ + +GM SY+W +P GR++A E+A F +L Sbjct 123 GVEKLIREGIEIGEFAGHLDANLTSFAILGMVNWSYQWFQPEGRKSAAEVAELFMDIVLH 182 Query 195 GL 196 G+ Sbjct 183 GI 184 >gi|302188049|ref|ZP_07264722.1| TetR family transcriptional regulator [Pseudomonas syringae pv. syringae 642] Length=201 Score = 89.0 bits (219), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 48/192 (25%), Positives = 103/192 (54%), Gaps = 14/192 (7%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 ++E+L+ A LFA +G+ ++D+A +G K+ VY+Y+ +K+ IL+ I+ + E Sbjct 18 QDEILSTAAILFADKGFRAITINDIAAGLGYTKSVVYYYFKNKNEILWQIFNRMYESYQQ 77 Query 73 AVHD------DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEV 126 ++ + P+ T RE LYQ+ ++++ A+YF+++ + EQ + Sbjct 78 SIDEVIGKSQSPTETLREILYQHALQVM----KRKHWTAIYFRDESELE----PEQQNLM 129 Query 127 REKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAA 186 R+++++ + + G+ G F + SH+ G++GM S+ W +G TA++IA Sbjct 130 RKRKREYDASIEKVYQEGVKEGVFVDIPSHIAVSGFLGMCNWSHTWFNDNGSHTAEQIAG 189 Query 187 EFSTALLRGLIR 198 + + + +G ++ Sbjct 190 YYCSIMSKGYLK 201 >gi|331695917|ref|YP_004332156.1| TetR family transcriptional regulator [Pseudonocardia dioxanivorans CB1190] gi|326950606|gb|AEA24303.1| transcriptional regulator, TetR family [Pseudonocardia dioxanivorans CB1190] Length=214 Score = 89.0 bits (219), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 55/188 (30%), Positives = 85/188 (46%), Gaps = 6/188 (3%) Query 11 SRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGT 70 SR E++ A +LF RGYH T MDD+A +G+ K T+YH+ SK IL I+ A+ Sbjct 22 SRHREIVRAAARLFDERGYHHTSMDDIAAAVGIKKPTLYHHVPSKGRILARIHDDLADRL 81 Query 71 LAAVHD--DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVRE 128 L + + D L L + P Y++ + E A R Sbjct 82 LGRLRERIDTGAAPAAVLLGVLEDHLELLDREPANLRCYYEHR----RELPPEDEAHSRA 137 Query 129 KEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 + + + V +++ G+A G+F D + L + G+ SY+W RP G A+ IA F Sbjct 138 RRDEYFAAVLAVVEDGVARGDFAVTDPRLATLAFFGVCNWSYQWYRPGGAMAARAIAVSF 197 Query 189 STALLRGL 196 L G+ Sbjct 198 WRCFLSGI 205 >gi|326384056|ref|ZP_08205739.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] gi|326197216|gb|EGD54407.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] Length=199 Score = 88.6 bits (218), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 101/200 (51%), Gaps = 6/200 (3%) Query 1 MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF 60 M S TS GLSRR+ELL +A +LFA RG T + D+AD G+ ++YH++ SK ++ Sbjct 1 MASKTSTTGLSRRDELLGIAGQLFADRGLRSTTVRDIADAAGILSGSLYHHFDSKESMVD 60 Query 61 DIYRQAAEGTLAAVHD--DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWF 118 ++ R + A D D +A + + Q + AI S A+Y E + Sbjct 61 ELLRGFLDSLFARYRDITDAGLSATDTIRQLVIASFEAIDSRHTAVAIYQNESRQLIAQE 120 Query 119 TSEQVAEVREKEQQVYEHVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSG 177 E +AE + ++++E V + RG+ G+F + D +V + RW RP G Sbjct 121 RFEYIAERNLEFRKLWESV---LRRGVQEGDFRADLDIDLVYRFMRDTVWVAVRWYRPGG 177 Query 178 RRTAKEIAAEFSTALLRGLI 197 T ++IA ++ + +L G++ Sbjct 178 SMTVEQIADQYLSIVLDGIL 197 >gi|317121320|ref|YP_004101323.1| regulatory protein TetR [Thermaerobacter marianensis DSM 12885] gi|315591300|gb|ADU50596.1| regulatory protein TetR [Thermaerobacter marianensis DSM 12885] Length=200 Score = 88.6 bits (218), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 65/207 (32%), Positives = 95/207 (46%), Gaps = 16/207 (7%) Query 11 SRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGT 70 R +E+L A KLF +GY+ T M D+A+ +GL KA++YHY SK +L Q A T Sbjct 3 GREQEILDAARKLFRQKGYYATTMQDIAEAVGLQKASLYHYIRSKEALLL----QVAGET 58 Query 71 LAAVHDDPSWTAREALYQYTVRLLTAI-------ASNPERAAVYFQEQPYITEWFTSEQV 123 + H + A Y +L AI A + E V F+E + E Sbjct 59 MRLFHAELDRI-EAAGGSYAEQLAAAIRAHVRVVAEHQETLTVLFRE----SHALPPEHA 113 Query 124 AEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKE 183 +VR + ++ + LI RG+A+GEF D L +G YRW GR + +E Sbjct 114 EKVRGETRRYTRRLTDLIARGVAAGEFRPVDPGAACLAILGACNWMYRWYSAEGRLSPQE 173 Query 184 IAAEFSTALLRGLIRDESIRNQSPLGT 210 IA +F +L GL+ +P G Sbjct 174 IADQFVQVILHGLVLPRGGPAGTPAGV 200 >gi|295694802|ref|YP_003588040.1| TetR family transcriptional regulator [Bacillus tusciae DSM 2912] gi|295410404|gb|ADG04896.1| transcriptional regulator, TetR family [Bacillus tusciae DSM 2912] Length=192 Score = 88.6 bits (218), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 57/188 (31%), Positives = 95/188 (51%), Gaps = 6/188 (3%) Query 11 SRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGT 70 ++ EE+ A A +LF +GYH T + D+AD +GL K ++YHY ASK +L I QA G Sbjct 4 NKYEEIAAAAIQLFEQKGYHATSVQDIADAVGLQKGSLYHYIASKEELLLKITHQAINGF 63 Query 71 LAAVHD--DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVRE 128 + + + D + E Q + I + V +E + E +E + ++ + Sbjct 64 VRRLEEIIDTNLPVEERFRQGIRTHMQYITQYLSMSTVLLREAFSLGEPH-NEVIRDLTD 122 Query 129 KEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 + ++ + I+ G+A+G F DS + AL +G YRW + G+ TA+EIA + Sbjct 123 RYLNLWTQI---INEGVAAGVFSVKDSRIAALTILGSCNWVYRWFKEEGKYTAEEIADQM 179 Query 189 STALLRGL 196 + L GL Sbjct 180 ANLFLDGL 187 >gi|288555718|ref|YP_003427653.1| TetR/AcrR family transcriptional regulator [Bacillus pseudofirmus OF4] gi|288546878|gb|ADC50761.1| TetR/AcrR family transcriptional regulator [Bacillus pseudofirmus OF4] Length=187 Score = 88.2 bits (217), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 52/187 (28%), Positives = 95/187 (51%), Gaps = 7/187 (3%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 +E+++ V+ LF G+ T + D+ DV+G+ K T Y+Y+ SK +L +I+ + E L Sbjct 2 KEKIIEVSIDLFGKNGFTETSIQDIVDVLGVTKGTFYYYFKSKEELLMEIHLRYIEDLLM 61 Query 73 AVHD--DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKE 130 + + + + TA L+ L+ I + A V+F+E ++ E E + ++ +K Sbjct 62 SQREIIEKTKTAEARLFDMVYMLMKHIEGQGQSARVFFREMQHLNE----EHLKDIFKKR 117 Query 131 QQVYEHVHGLIDRGIASGEFYE-CDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEFS 189 +++ +I G+ SGEF E D ++V L +G SY W P G K ++ + Sbjct 118 DAFRLNMNQVIADGVESGEFREDLDVNIVTLAILGAVNWSYHWFDPKGALDEKAVSTIYI 177 Query 190 TALLRGL 196 +L GL Sbjct 178 DFMLNGL 184 >gi|226355062|ref|YP_002784802.1| TetR family transcriptional regulator [Deinococcus deserti VCD115] gi|226317052|gb|ACO45048.1| putative Transcriptional regulator, TetR family [Deinococcus deserti VCD115] Length=200 Score = 88.2 bits (217), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 57/193 (30%), Positives = 101/193 (53%), Gaps = 15/193 (7%) Query 12 RREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAA---E 68 RRE++L A++LF+ RGYH T M D+A +G+ ++Y + + K +L +I QA+ + Sbjct 8 RREQILDSASRLFSERGYHATSMRDLAGELGMQGGSLYAHISGKEELLIEIVNQASAQFD 67 Query 69 GTLAAVHDDPSWTA---REALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAE 125 L + DDP A REA++ R + +A N + A V+F E ++ + + A Sbjct 68 TALFYLRDDPRPAADKLREAMH----RHIRVVADNMDSATVFFHEWKHL----SPDAYAR 119 Query 126 VREKEQQVYEHVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEI 184 V + + L+ +GI G+F + D + A + +Y W RP G+ T +++ Sbjct 120 VTSWRDTIDQFYRDLVTQGIEQGQFRADLDPKMTANLILSAVNWAYTWYRPGGQMTPRDV 179 Query 185 AAEFSTALLRGLI 197 A +++ LL GL+ Sbjct 180 ADQYADMLLGGLL 192 >gi|311106114|ref|YP_003978967.1| TetR family transcriptional regulator [Achromobacter xylosoxidans A8] gi|310760803|gb|ADP16252.1| bacterial regulatory protein, TetR family protein 11 [Achromobacter xylosoxidans A8] Length=236 Score = 88.2 bits (217), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 65/207 (32%), Positives = 97/207 (47%), Gaps = 15/207 (7%) Query 8 NGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF----DIY 63 G + R +L A LF RG GT + D+A+ +GL++ VY+Y+ SK IL D+ Sbjct 11 KGEALRTAILDAAATLFIKRGSGGTSIQDIAESLGLSRTAVYYYFKSKDAILRSLTEDVL 70 Query 64 RQAAE--GTLAAVHD-DPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS 120 A + G A D DP R + Q+ +L+ A F+ T Sbjct 71 SAAKKMAGETATREDLDPVEALRALVTQHADLILSRTAE--------FRVADRTEADMTP 122 Query 121 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT 180 +Q A V+ + V E+ +I+ GI G+F D HV A IGM S W +P GR Sbjct 123 KQRAAVQASRRNVLENFSRVIENGIRDGQFRMVDPHVAAFSLIGMCNWSAWWYKPDGRLG 182 Query 181 AKEIAAEFSTALLRGLIRDESIRNQSP 207 E+AA + ++ L+RD + R +SP Sbjct 183 RAEVAAIMADMAVQSLLRDAARRPRSP 209 >gi|325002291|ref|ZP_08123403.1| TetR family transcriptional regulator [Pseudonocardia sp. P1] Length=233 Score = 88.2 bits (217), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 60/206 (30%), Positives = 99/206 (49%), Gaps = 14/206 (6%) Query 11 SRRE----ELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQA 66 +RRE EL AT+LFA RG+ GT + D+AD +G+ + +Y+Y SK +L + + Sbjct 12 ARRELVENELYEHATRLFAERGFAGTSLQDIADALGITRPALYYYVRSKDELLAKLVTEV 71 Query 67 AEGT---LAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQV 123 G L A+ D + A + L ++ + PER + + + + E T Sbjct 72 TNGPLDELEALAGDDALDAVDKLRGIVRIIVGRRTTQPERFRLLIRSEAELPEELT---- 127 Query 124 AEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKE 183 A E + + + + G+ID G+ G F D+ V ALG +GM W P GR T + Sbjct 128 AAYDESRRTILKVIAGVIDDGVRGGRFRPVDARVAALGVLGMCNWVAWWFHPGGRDTTEG 187 Query 184 IAAEFSTALLRGLIRDESIRNQSPLG 209 + A+ + + L+R + +Q P G Sbjct 188 VTAQLADMAVGALVRPD---DQMPDG 210 >gi|56420194|ref|YP_147512.1| TetR/AcrR family transcriptional regulator [Geobacillus kaustophilus HTA426] gi|261419895|ref|YP_003253577.1| TetR family transcriptional regulator [Geobacillus sp. Y412MC61] gi|297530145|ref|YP_003671420.1| TetR family transcriptional regulator [Geobacillus sp. C56-T3] gi|319766710|ref|YP_004132211.1| TetR family transcriptional regulator [Geobacillus sp. Y412MC52] gi|56380036|dbj|BAD75944.1| transcriptional regulator (TetR/AcrR family) [Geobacillus kaustophilus HTA426] gi|261376352|gb|ACX79095.1| transcriptional regulator, TetR family [Geobacillus sp. Y412MC61] gi|297253397|gb|ADI26843.1| transcriptional regulator, TetR family [Geobacillus sp. C56-T3] gi|317111576|gb|ADU94068.1| transcriptional regulator, TetR family [Geobacillus sp. Y412MC52] Length=208 Score = 86.7 bits (213), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 58/205 (29%), Positives = 100/205 (49%), Gaps = 11/205 (5%) Query 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTL- 71 +E+L VA +LF +G+ T + ++ + IG K Y+YY SK +L DI + L Sbjct 2 KEKLREVAIELFERKGFKETSVQEIVEAIGATKGAFYYYYKSKEELLCDICVSYLDDLLR 61 Query 72 --AAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREK 129 A + DP + E L ++ I + + A ++F+E ++ + + +AE+R K Sbjct 62 QQACIVQDPEKSCTEKLRAIVHMVICNIRTRKKSARIFFREMRHLAD----DHLAEIRAK 117 Query 130 EQQVYEHVHGLIDRGIASGEFY-ECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF 188 + + L+ GIA GEF + ++ G +G+T SY W RP G + +E+ F Sbjct 118 RRLFRKRYEQLVREGIARGEFKPSLHAEMITFGLLGITNWSYYWFRPDGGISEEELTDIF 177 Query 189 STALLRGLI---RDESIRNQSPLGT 210 +L G+ ES RN++ G Sbjct 178 VDFILHGIKAPRAGESGRNEAEPGN 202 Lambda K H 0.318 0.132 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 254328062080 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40