BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0164

Length=161
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15839543|ref|NP_334580.1|  hypothetical protein MT0173 [Mycoba...   332    1e-89
gi|289441539|ref|ZP_06431283.1|  conserved hypothetical protein [...   331    2e-89
gi|340625201|ref|YP_004743653.1|  hypothetical protein MCAN_01701...   329    8e-89
gi|167970285|ref|ZP_02552562.1|  hypothetical protein MtubH3_2056...   299    9e-80
gi|308231482|ref|ZP_07412591.2|  hypothetical protein TMAG_01300 ...   292    1e-77
gi|41409696|ref|NP_962532.1|  hypothetical protein MAP3598 [Mycob...   259    8e-68
gi|240168184|ref|ZP_04746843.1|  hypothetical protein MkanA1_0263...   258    2e-67
gi|289764280|ref|ZP_06523658.1|  conserved hypothetical protein [...   249    8e-65
gi|183980438|ref|YP_001848729.1|  hypothetical protein MMAR_0407 ...   249    8e-65
gi|118616791|ref|YP_905123.1|  hypothetical protein MUL_1057 [Myc...   248    2e-64
gi|118466430|ref|YP_884140.1|  cyclase/dehydrase [Mycobacterium a...   246    9e-64
gi|15828420|ref|NP_302683.1|  hypothetical protein ML2629 [Mycoba...   242    1e-62
gi|254822931|ref|ZP_05227932.1|  hypothetical protein MintA_23589...   238    3e-61
gi|342859382|ref|ZP_08716036.1|  hypothetical protein MCOL_10898 ...   234    2e-60
gi|296167377|ref|ZP_06849779.1|  cyclase/dehydratase [Mycobacteri...   234    3e-60
gi|15826955|ref|NP_301218.1|  hypothetical protein ML0124 [Mycoba...   213    5e-54
gi|333988758|ref|YP_004521372.1|  hypothetical protein JDM601_011...   212    2e-53
gi|108797093|ref|YP_637290.1|  hypothetical protein Mmcs_0113 [My...   208    2e-52
gi|145221311|ref|YP_001131989.1|  cyclase/dehydrase [Mycobacteriu...   207    4e-52
gi|120401157|ref|YP_950986.1|  cyclase/dehydrase [Mycobacterium v...   205    2e-51
gi|118473269|ref|YP_884545.1|  cyclase/dehydrase [Mycobacterium s...   178    2e-43
gi|169631646|ref|YP_001705295.1|  hypothetical protein MAB_4572c ...   141    4e-32
gi|226366139|ref|YP_002783922.1|  hypothetical protein ROP_67300 ...  73.6    1e-11
gi|111023701|ref|YP_706673.1|  hypothetical protein RHA1_ro06743 ...  71.6    4e-11
gi|118465100|ref|YP_880235.1|  cyclase/dehydrase [Mycobacterium a...  65.9    2e-09
gi|240171441|ref|ZP_04750100.1|  hypothetical protein MkanA1_1916...  65.5    2e-09
gi|291450893|ref|ZP_06590283.1|  cyclase/dehydrase [Streptomyces ...  64.7    4e-09
gi|226306216|ref|YP_002766176.1|  hypothetical protein RER_27290 ...  64.3    6e-09
gi|229490868|ref|ZP_04384703.1|  cyclase/dehydrase [Rhodococcus e...  63.5    1e-08
gi|120406021|ref|YP_955850.1|  cyclase/dehydrase [Mycobacterium v...  63.2    1e-08
gi|239987099|ref|ZP_04707763.1|  hypothetical protein SrosN1_0731...  63.2    1e-08
gi|41406882|ref|NP_959718.1|  hypothetical protein MAP0784 [Mycob...  62.8    2e-08
gi|111018708|ref|YP_701680.1|  hypothetical protein RHA1_ro01709 ...  62.8    2e-08
gi|328881837|emb|CCA55076.1|  hypothetical protein SVEN_1789 [Str...  62.4    2e-08
gi|297161241|gb|ADI10953.1|  hypothetical protein SBI_07833 [Stre...  61.2    4e-08
gi|182439167|ref|YP_001826886.1|  hypothetical protein SGR_5374 [...  61.2    4e-08
gi|345014505|ref|YP_004816859.1|  cyclase/dehydrase [Streptomyces...  60.5    9e-08
gi|111219669|ref|YP_710463.1|  hypothetical protein FRAAL0171 [Fr...  60.5    9e-08
gi|108801463|ref|YP_641660.1|  cyclase/dehydrase [Mycobacterium s...  60.5    9e-08
gi|254818313|ref|ZP_05223314.1|  cyclase/dehydrase superfamily pr...  60.1    1e-07
gi|145222270|ref|YP_001132948.1|  cyclase/dehydrase [Mycobacteriu...  60.1    1e-07
gi|315442701|ref|YP_004075580.1|  polyketide cyclase / dehydrase ...  59.7    1e-07
gi|331696583|ref|YP_004332822.1|  cyclase/dehydrase [Pseudonocard...  59.3    2e-07
gi|297199107|ref|ZP_06916504.1|  cyclase/dehydrase [Streptomyces ...  59.3    2e-07
gi|342860457|ref|ZP_08717108.1|  cyclase/dehydrase [Mycobacterium...  58.9    3e-07
gi|256375524|ref|YP_003099184.1|  cyclase/dehydrase [Actinosynnem...  58.5    3e-07
gi|254393052|ref|ZP_05008214.1|  cyclase/dehydrase [Streptomyces ...  58.5    3e-07
gi|118471284|ref|YP_889969.1|  cyclase/dehydrase [Mycobacterium s...  58.5    3e-07
gi|319950670|ref|ZP_08024571.1|  cyclase/dehydrase [Dietzia cinna...  58.5    4e-07
gi|21220606|ref|NP_626385.1|  hypothetical protein SCO2129 [Strep...  57.8    5e-07


>gi|15839543|ref|NP_334580.1| hypothetical protein MT0173 [Mycobacterium tuberculosis CDC1551]
 gi|31791342|ref|NP_853835.1| hypothetical protein Mb0169 [Mycobacterium bovis AF2122/97]
 gi|57116699|ref|YP_177617.1| hypothetical protein Rv0164 [Mycobacterium tuberculosis H37Rv]
 38 more sequence titles
 Length=161

 Score =  332 bits (851),  Expect = 1e-89, Method: Compositional matrix adjust.
 Identities = 161/161 (100%), Positives = 161/161 (100%), Gaps = 0/161 (0%)

Query  1    MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD  60
            MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD
Sbjct  1    MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD  60

Query  61   GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT  120
            GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT
Sbjct  61   GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT  120

Query  121  VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS
Sbjct  121  VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161


>gi|289441539|ref|ZP_06431283.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289568062|ref|ZP_06448289.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289748640|ref|ZP_06508018.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289414458|gb|EFD11698.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289541815|gb|EFD45464.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289689227|gb|EFD56656.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
Length=161

 Score =  331 bits (849),  Expect = 2e-89, Method: Compositional matrix adjust.
 Identities = 160/161 (99%), Positives = 161/161 (100%), Gaps = 0/161 (0%)

Query  1    MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD  60
            MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD
Sbjct  1    MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD  60

Query  61   GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT  120
            GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT
Sbjct  61   GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT  120

Query  121  VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            VDMDVQVTMPVPEPMVKM+LNNVLEHLAENLKQRAEQLAAS
Sbjct  121  VDMDVQVTMPVPEPMVKMMLNNVLEHLAENLKQRAEQLAAS  161


>gi|340625201|ref|YP_004743653.1| hypothetical protein MCAN_01701 [Mycobacterium canettii CIPT 
140010059]
 gi|340003391|emb|CCC42511.1| conserved hypothetical protein TB18.5 [Mycobacterium canettii 
CIPT 140010059]
Length=161

 Score =  329 bits (844),  Expect = 8e-89, Method: Compositional matrix adjust.
 Identities = 160/161 (99%), Positives = 160/161 (99%), Gaps = 0/161 (0%)

Query  1    MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD  60
            MTAI CSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD
Sbjct  1    MTAILCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDD  60

Query  61   GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT  120
            GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT
Sbjct  61   GRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLT  120

Query  121  VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS
Sbjct  121  VDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161


>gi|167970285|ref|ZP_02552562.1| hypothetical protein MtubH3_20563 [Mycobacterium tuberculosis 
H37Ra]
 gi|254549102|ref|ZP_05139549.1| hypothetical protein Mtube_01331 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|297632641|ref|ZP_06950421.1| hypothetical protein MtubK4_00881 [Mycobacterium tuberculosis 
KZN 4207]
 gi|297729616|ref|ZP_06958734.1| hypothetical protein MtubKR_00911 [Mycobacterium tuberculosis 
KZN R506]
 gi|313656943|ref|ZP_07813823.1| hypothetical protein MtubKV_00901 [Mycobacterium tuberculosis 
KZN V2475]
 gi|323717153|gb|EGB26362.1| hypothetical protein TMMG_00593 [Mycobacterium tuberculosis CDC1551A]
 gi|339293229|gb|AEJ45340.1| hypothetical protein CCDC5079_0150 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339296875|gb|AEJ48985.1| hypothetical protein CCDC5180_0148 [Mycobacterium tuberculosis 
CCDC5180]
Length=146

 Score =  299 bits (766),  Expect = 9e-80, Method: Compositional matrix adjust.
 Identities = 146/146 (100%), Positives = 146/146 (100%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI
Sbjct  1    MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM
Sbjct  61   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VKMLLNNVLEHLAENLKQRAEQLAAS
Sbjct  121  VKMLLNNVLEHLAENLKQRAEQLAAS  146


>gi|308231482|ref|ZP_07412591.2| hypothetical protein TMAG_01300 [Mycobacterium tuberculosis SUMu001]
 gi|308369319|ref|ZP_07417335.2| hypothetical protein TMBG_02635 [Mycobacterium tuberculosis SUMu002]
 gi|308370332|ref|ZP_07421108.2| hypothetical protein TMCG_02375 [Mycobacterium tuberculosis SUMu003]
 21 more sequence titles
 Length=143

 Score =  292 bits (748),  Expect = 1e-77, Method: Compositional matrix adjust.
 Identities = 142/143 (99%), Positives = 143/143 (100%), Gaps = 0/143 (0%)

Query  19   LSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT  78
            +SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT
Sbjct  1    MSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT  60

Query  79   YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKM  138
            YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKM
Sbjct  61   YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKM  120

Query  139  LLNNVLEHLAENLKQRAEQLAAS  161
            LLNNVLEHLAENLKQRAEQLAAS
Sbjct  121  LLNNVLEHLAENLKQRAEQLAAS  143


>gi|41409696|ref|NP_962532.1| hypothetical protein MAP3598 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41398528|gb|AAS06148.1| hypothetical protein MAP_3598 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=153

 Score =  259 bits (663),  Expect = 8e-68, Method: Compositional matrix adjust.
 Identities = 123/152 (81%), Positives = 135/152 (89%), Gaps = 0/152 (0%)

Query  10   PRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD  69
            PRYASRMPVLSKTVEV  DAA+IMAIVAD ERYPEW++GV G WVLARYDDGRPSQ+RLD
Sbjct  2    PRYASRMPVLSKTVEVNTDAAAIMAIVADFERYPEWSDGVTGCWVLARYDDGRPSQLRLD  61

Query  70   TAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTM  129
             A QG EG YI AVYYPG NQIQTVMQQGELF KQEQLFSVV  GA+SLLTVD+DV+ +M
Sbjct  62   AAYQGFEGVYIQAVYYPGPNQIQTVMQQGELFKKQEQLFSVVEMGASSLLTVDIDVEPSM  121

Query  130  PVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            PVP PMVK +LNNVL+HLA+NLKQRAEQLAA+
Sbjct  122  PVPAPMVKSMLNNVLDHLADNLKQRAEQLAAN  153


>gi|240168184|ref|ZP_04746843.1| hypothetical protein MkanA1_02637 [Mycobacterium kansasii ATCC 
12478]
Length=146

 Score =  258 bits (659),  Expect = 2e-67, Method: Compositional matrix adjust.
 Identities = 122/146 (84%), Positives = 132/146 (91%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MP+LSKTVEV+ADA +IM IVADIERYPEWNEG+KGAWVL RYDDGRPSQVRLDTA+QG 
Sbjct  1    MPLLSKTVEVSADAVAIMGIVADIERYPEWNEGIKGAWVLHRYDDGRPSQVRLDTAIQGF  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            EG YIHAVYYPGENQIQTVMQQG+LF KQEQLFSVV TGA SLLTVD+DV+ ++PVP PM
Sbjct  61   EGIYIHAVYYPGENQIQTVMQQGDLFLKQEQLFSVVETGANSLLTVDIDVEPSLPVPAPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VKMLLNNVLE LAENLKQRAE LA  
Sbjct  121  VKMLLNNVLEQLAENLKQRAEHLATG  146


>gi|289764280|ref|ZP_06523658.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|289711786|gb|EFD75802.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
Length=154

 Score =  249 bits (637),  Expect = 8e-65, Method: Compositional matrix adjust.
 Identities = 121/123 (99%), Positives = 121/123 (99%), Gaps = 0/123 (0%)

Query  39   IERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQG  98
             ERYPE NEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQG
Sbjct  32   FERYPELNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQG  91

Query  99   ELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQL  158
            ELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQL
Sbjct  92   ELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQL  151

Query  159  AAS  161
            AAS
Sbjct  152  AAS  154


>gi|183980438|ref|YP_001848729.1| hypothetical protein MMAR_0407 [Mycobacterium marinum M]
 gi|183173764|gb|ACC38874.1| conserved protein [Mycobacterium marinum M]
Length=153

 Score =  249 bits (637),  Expect = 8e-65, Method: Compositional matrix adjust.
 Identities = 129/152 (85%), Positives = 136/152 (90%), Gaps = 0/152 (0%)

Query  10   PRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD  69
            PRYAS MPVLSKTVEV+ADA SIM IVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD
Sbjct  2    PRYASPMPVLSKTVEVSADAGSIMGIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD  61

Query  70   TAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTM  129
             +VQG EG YIHAVYYPGENQIQTVMQQG+LF KQEQLFSVV  GAASLLTVD+DV+ +M
Sbjct  62   ASVQGFEGVYIHAVYYPGENQIQTVMQQGDLFLKQEQLFSVVEAGAASLLTVDIDVEPSM  121

Query  130  PVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            PVP PMVK+LLNNVLE LA NLK RAEQL A 
Sbjct  122  PVPPPMVKLLLNNVLEQLAANLKLRAEQLTAG  153


>gi|118616791|ref|YP_905123.1| hypothetical protein MUL_1057 [Mycobacterium ulcerans Agy99]
 gi|118568901|gb|ABL03652.1| conserved protein [Mycobacterium ulcerans Agy99]
Length=153

 Score =  248 bits (633),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 128/152 (85%), Positives = 135/152 (89%), Gaps = 0/152 (0%)

Query  10   PRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD  69
            PRYAS MPVLSKTVEV+ADA SIM IVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD
Sbjct  2    PRYASPMPVLSKTVEVSADAGSIMGIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD  61

Query  70   TAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTM  129
             +VQG EG YIHAVYYPGENQIQTVMQQG+LF KQEQLFSVV  GA SLLTVD+DV+ +M
Sbjct  62   ASVQGFEGVYIHAVYYPGENQIQTVMQQGDLFLKQEQLFSVVEAGAVSLLTVDIDVEPSM  121

Query  130  PVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            PVP PMVK+LLNNVLE LA NLK RAEQL A 
Sbjct  122  PVPPPMVKLLLNNVLEQLAANLKLRAEQLTAG  153


>gi|118466430|ref|YP_884140.1| cyclase/dehydrase [Mycobacterium avium 104]
 gi|254776562|ref|ZP_05218078.1| cyclase/dehydrase superfamily protein [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|118167717|gb|ABK68614.1| cyclase/dehydrase superfamily protein [Mycobacterium avium 104]
 gi|336459865|gb|EGO38777.1| oligoketide cyclase/lipid transport protein [Mycobacterium avium 
subsp. paratuberculosis S397]
Length=146

 Score =  246 bits (628),  Expect = 9e-64, Method: Compositional matrix adjust.
 Identities = 117/146 (81%), Positives = 129/146 (89%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPVLSKTVEV  DAA+IMAIVAD ERYPEW++GV G WVLARYDDGRPSQ+RLD A QG 
Sbjct  1    MPVLSKTVEVNTDAAAIMAIVADFERYPEWSDGVTGCWVLARYDDGRPSQLRLDAAYQGF  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            EG YI AVYYPG NQIQTVMQQGELF KQEQLFSVV  GA+SLLTVD+DV+ +MPVP PM
Sbjct  61   EGVYIQAVYYPGPNQIQTVMQQGELFKKQEQLFSVVEMGASSLLTVDIDVEPSMPVPAPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VK +LNNVL+HLA+NLKQRAEQLAA+
Sbjct  121  VKSMLNNVLDHLADNLKQRAEQLAAN  146


>gi|15828420|ref|NP_302683.1| hypothetical protein ML2629 [Mycobacterium leprae TN]
 gi|221230897|ref|YP_002504313.1| hypothetical protein MLBr_02629 [Mycobacterium leprae Br4923]
 gi|2104615|emb|CAB08818.1| unknown [Mycobacterium leprae]
 gi|13093850|emb|CAC32161.1| hypothetical protein [Mycobacterium leprae]
 gi|219934004|emb|CAR72729.1| hypothetical protein MLBr02629 [Mycobacterium leprae Br4923]
Length=156

 Score =  242 bits (618),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 116/152 (77%), Positives = 130/152 (86%), Gaps = 0/152 (0%)

Query  10   PRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLD  69
            P YAS MPV+SKTVEV A AASIMAIV D E YP+WN+GVKG WVLARYDDGRPSQ+RLD
Sbjct  5    PGYASPMPVMSKTVEVRATAASIMAIVTDFEAYPQWNDGVKGVWVLARYDDGRPSQLRLD  64

Query  70   TAVQGIEGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTM  129
            T +QG + TYI AVYYP  NQIQT+MQQG+LF KQEQLFS V  GAASLLTVD+DV+ +M
Sbjct  65   TEIQGTKCTYIQAVYYPATNQIQTIMQQGDLFTKQEQLFSAVEIGAASLLTVDIDVESSM  124

Query  130  PVPEPMVKMLLNNVLEHLAENLKQRAEQLAAS  161
            PVP PMVK LLNNVL++LAENLK RAEQLAA+
Sbjct  125  PVPAPMVKALLNNVLDNLAENLKLRAEQLAAN  156


>gi|254822931|ref|ZP_05227932.1| hypothetical protein MintA_23589 [Mycobacterium intracellulare 
ATCC 13950]
Length=146

 Score =  238 bits (606),  Expect = 3e-61, Method: Compositional matrix adjust.
 Identities = 111/146 (77%), Positives = 127/146 (87%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPVLSKTVE+ ADA  IM IV D E YP+WNE +KG WVLARYDDGRPSQ+RLDT  QG+
Sbjct  1    MPVLSKTVEIGADAGLIMKIVGDFEAYPQWNEEIKGLWVLARYDDGRPSQLRLDTDYQGM  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            +  +I AVYYPGENQIQTV+QQG+LF KQEQLFSVVA GA+SLLTVD+DV+ +MPVP PM
Sbjct  61   QSMFIQAVYYPGENQIQTVLQQGDLFTKQEQLFSVVAMGASSLLTVDLDVETSMPVPAPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VK LLNNVL+HLAE+LKQRAEQLAA+
Sbjct  121  VKQLLNNVLDHLAESLKQRAEQLAAT  146


>gi|342859382|ref|ZP_08716036.1| hypothetical protein MCOL_10898 [Mycobacterium colombiense CECT 
3035]
 gi|342133623|gb|EGT86826.1| hypothetical protein MCOL_10898 [Mycobacterium colombiense CECT 
3035]
Length=146

 Score =  234 bits (598),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 110/146 (76%), Positives = 127/146 (87%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPV+SKTVEV ADAA IM IV D E YP+WNE +KG WVLARYDDGRPSQ+RLDT  QG+
Sbjct  1    MPVMSKTVEVDADAALIMRIVGDFEAYPQWNEEIKGLWVLARYDDGRPSQLRLDTDYQGM  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            +  +I AVYYPG+NQIQTV+QQG+LF KQEQLFSVV  GA+SLLTVD+DV+ +MPVP PM
Sbjct  61   QSMFIQAVYYPGDNQIQTVLQQGDLFTKQEQLFSVVPMGASSLLTVDLDVETSMPVPAPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VK LLNNVL+HLAE+LKQRAEQLAA+
Sbjct  121  VKQLLNNVLDHLAESLKQRAEQLAAT  146


>gi|296167377|ref|ZP_06849779.1| cyclase/dehydratase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897321|gb|EFG76925.1| cyclase/dehydratase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=145

 Score =  234 bits (597),  Expect = 3e-60, Method: Compositional matrix adjust.
 Identities = 109/145 (76%), Positives = 126/145 (87%), Gaps = 0/145 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPV+SKTVEV+A+AA+IM+IVAD E YP+WNE VKG WVLARYDDGRPSQ+RLDT  QG+
Sbjct  1    MPVMSKTVEVSANAATIMSIVADFEAYPQWNEEVKGLWVLARYDDGRPSQLRLDTDYQGM  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            +G +I AVYYPGENQIQTV+QQG+LF KQEQLFSVV  G +SLLTVD+DV+ +MPVP PM
Sbjct  61   QGVFIQAVYYPGENQIQTVLQQGDLFTKQEQLFSVVEMGTSSLLTVDLDVETSMPVPAPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAA  160
            VK LLNNVL+HLA  LKQRAEQL  
Sbjct  121  VKQLLNNVLDHLAGKLKQRAEQLTG  145


>gi|15826955|ref|NP_301218.1| hypothetical protein ML0124 [Mycobacterium leprae TN]
 gi|221229433|ref|YP_002502849.1| hypothetical protein MLBr_00124 [Mycobacterium leprae Br4923]
 gi|13092502|emb|CAC29632.1| conserved hypothetical protein [Mycobacterium leprae]
 gi|219932540|emb|CAR70217.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=146

 Score =  213 bits (543),  Expect = 5e-54, Method: Compositional matrix adjust.
 Identities = 100/146 (69%), Positives = 117/146 (81%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPVLSKTVE+  D A+IMAIV D E YP+W+E +KG WVLA YDDGRPSQ+R+D   QG+
Sbjct  1    MPVLSKTVEIDTDTATIMAIVTDFESYPQWHEWIKGVWVLAHYDDGRPSQLRIDINFQGM  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
            +GTYI AVYYPG NQIQTVMQQG+L++KQEQLFSV      S+LTVD+DV++TMPVP PM
Sbjct  61   QGTYIQAVYYPGVNQIQTVMQQGDLYSKQEQLFSVTQAEGGSVLTVDLDVELTMPVPAPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VKMLLN  L+ LAE LK  AE LA S
Sbjct  121  VKMLLNTALDRLAEKLKLYAEHLAPS  146


>gi|333988758|ref|YP_004521372.1| hypothetical protein JDM601_0118 [Mycobacterium sp. JDM601]
 gi|333484726|gb|AEF34118.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=143

 Score =  212 bits (539),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 97/143 (68%), Positives = 117/143 (82%), Gaps = 0/143 (0%)

Query  19   LSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT  78
            +SKTVEV ADAA+IM IVAD E YP+WN+ VKG WVLARYDDGRPSQ+RLD +  G +GT
Sbjct  1    MSKTVEVAADAATIMGIVADFEAYPQWNDEVKGIWVLARYDDGRPSQLRLDASYSGFDGT  60

Query  79   YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKM  138
            +I AVYYP   QIQTV+QQG+LF+KQEQLFSVV  G  +LLTVDMD++  M VP+PM+K 
Sbjct  61   FIQAVYYPSGTQIQTVLQQGDLFSKQEQLFSVVEIGPTTLLTVDMDIETEMSVPKPMLKK  120

Query  139  LLNNVLEHLAENLKQRAEQLAAS  161
              NN L++LA+NLK+RAEQLAA 
Sbjct  121  AFNNALDYLADNLKRRAEQLAAG  143


>gi|108797093|ref|YP_637290.1| hypothetical protein Mmcs_0113 [Mycobacterium sp. MCS]
 gi|119866178|ref|YP_936130.1| cyclase/dehydrase [Mycobacterium sp. KMS]
 gi|126432716|ref|YP_001068407.1| cyclase/dehydrase [Mycobacterium sp. JLS]
 gi|108767512|gb|ABG06234.1| conserved hypothetical protein [Mycobacterium sp. MCS]
 gi|119692267|gb|ABL89340.1| cyclase/dehydrase [Mycobacterium sp. KMS]
 gi|126232516|gb|ABN95916.1| cyclase/dehydrase [Mycobacterium sp. JLS]
Length=148

 Score =  208 bits (529),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 96/146 (66%), Positives = 118/146 (81%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MP++SKTVEV A A +IMAIVAD ER+PEWN  +KG W+LARYDDGRPSQ+RLD  VQG 
Sbjct  1    MPLVSKTVEVEAPAEAIMAIVADFERFPEWNPEIKGCWILARYDDGRPSQLRLDVEVQGQ  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
             GT+I+AVYYPGENQI T++QQG+ F K EQ FSVV+ GA+SLLTVDMDV+  +P+P+PM
Sbjct  61   AGTFINAVYYPGENQIFTLLQQGDHFDKHEQRFSVVSIGASSLLTVDMDVETKLPIPKPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VK  +   L++LA+NLK RAE L A 
Sbjct  121  VKKAIGETLDYLADNLKARAEHLGAG  146


>gi|145221311|ref|YP_001131989.1| cyclase/dehydrase [Mycobacterium gilvum PYR-GCK]
 gi|315441801|ref|YP_004074680.1| polyketide cyclase / dehydrase family protein [Mycobacterium 
sp. Spyr1]
 gi|145213797|gb|ABP43201.1| cyclase/dehydrase [Mycobacterium gilvum PYR-GCK]
 gi|315260104|gb|ADT96845.1| polyketide cyclase / dehydrase family protein [Mycobacterium 
sp. Spyr1]
Length=146

 Score =  207 bits (527),  Expect = 4e-52, Method: Compositional matrix adjust.
 Identities = 97/146 (67%), Positives = 119/146 (82%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MP++SKTVEV+A A +IMAIVAD E+YPEWNE +KG W+LARY+DGRPSQ+RLD  VQG 
Sbjct  1    MPLVSKTVEVSASAETIMAIVADFEKYPEWNEEIKGCWILARYNDGRPSQLRLDVVVQGQ  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
             GT+I AVYYP ENQI T++QQG+ F KQEQ F+VV  G  SLLTVD+DV+V+MPVP  M
Sbjct  61   AGTFITAVYYPAENQIFTMLQQGDHFTKQEQRFAVVPMGPTSLLTVDLDVEVSMPVPAVM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VK ++ + L++LAENLK RAE L AS
Sbjct  121  VKKVIGDTLDYLAENLKTRAEHLTAS  146


>gi|120401157|ref|YP_950986.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1]
 gi|119953975|gb|ABM10980.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1]
Length=146

 Score =  205 bits (521),  Expect = 2e-51, Method: Compositional matrix adjust.
 Identities = 97/146 (67%), Positives = 119/146 (82%), Gaps = 0/146 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MP++SKTVEV A A +IM IVAD E YP+WNE +KG WVLARY+DGRPSQ+RLD  VQG 
Sbjct  1    MPLVSKTVEVEAAAETIMGIVADFESYPQWNEEIKGCWVLARYNDGRPSQLRLDVVVQGQ  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
             GT+I AVYYPGENQI TV+QQG+  +KQEQ FSVVA GA SLLTVD++V+V M VP  M
Sbjct  61   AGTFITAVYYPGENQIYTVLQQGDHLSKQEQRFSVVAMGATSLLTVDLEVEVKMAVPNAM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAAS  161
            VK ++ + L++LA+NLK RAEQLA++
Sbjct  121  VKKIVGDTLDYLADNLKTRAEQLAST  146


>gi|118473269|ref|YP_884545.1| cyclase/dehydrase [Mycobacterium smegmatis str. MC2 155]
 gi|118174556|gb|ABK75452.1| cyclase/dehydrase family protein [Mycobacterium smegmatis str. 
MC2 155]
Length=144

 Score =  178 bits (452),  Expect = 2e-43, Method: Compositional matrix adjust.
 Identities = 85/144 (60%), Positives = 107/144 (75%), Gaps = 1/144 (0%)

Query  19   LSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT  78
            +SKTVEV A A +I +IV+D E YP+WN  +KG W+LARY+DGRPSQ+RLD  +QG  G 
Sbjct  1    MSKTVEVAASAETITSIVSDFEAYPQWNPEIKGCWILARYNDGRPSQLRLDVEIQGQSGV  60

Query  79   YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGA-ASLLTVDMDVQVTMPVPEPMVK  137
            +I AVYYP ENQI T++QQG+ F KQEQ FS+V  G  ++LL VD+DV+V +PVP PMVK
Sbjct  61   FITAVYYPAENQIFTMLQQGDHFTKQEQRFSIVPLGPDSTLLQVDLDVEVKLPVPGPMVK  120

Query  138  MLLNNVLEHLAENLKQRAEQLAAS  161
             L    LEHLA+ L+ R EQL  S
Sbjct  121  KLAGETLEHLAKALEGRVEQLTQS  144


>gi|169631646|ref|YP_001705295.1| hypothetical protein MAB_4572c [Mycobacterium abscessus ATCC 
19977]
 gi|169243613|emb|CAM64641.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=160

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 70/145 (49%), Positives = 93/145 (65%), Gaps = 0/145 (0%)

Query  16   MPVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGI  75
            MPV+S+TVEV A    I++IV + E YPEWN+ +    +L R  DGRP  VRL     G+
Sbjct  1    MPVVSQTVEVAAPPQVIVSIVTNYEAYPEWNKEIASVDILQRLPDGRPHIVRLKVETSGM  60

Query  76   EGTYIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
              T +  + Y    Q+ T + + ++F KQEQ FS+V  G   LLTVDMDV+  +P+P+PM
Sbjct  61   SSTNVAEIAYLNAAQVATRLLESDIFEKQEQTFSIVPMGQTCLLTVDMDVETKLPIPKPM  120

Query  136  VKMLLNNVLEHLAENLKQRAEQLAA  160
            VK L N VLEHLAE LK RAE +A+
Sbjct  121  VKKLANQVLEHLAEGLKGRAEAIAS  145


>gi|226366139|ref|YP_002783922.1| hypothetical protein ROP_67300 [Rhodococcus opacus B4]
 gi|226244629|dbj|BAH54977.1| hypothetical protein [Rhodococcus opacus B4]
Length=144

 Score = 73.6 bits (179),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 40/139 (29%), Positives = 76/139 (55%), Gaps = 2/139 (1%)

Query  21   KTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYI  80
            K  E+ AD A++MA +A ++R PEW+   K   + + +DDGRP +VR+  ++ GI    +
Sbjct  7    KEFEIKADPATVMAAIAAVDRLPEWSSAHKSVTIESTHDDGRPHRVRMSVSILGISDEQV  66

Query  81   HAVYYPGENQIQ-TVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
                + G+N +   +++ G+  A Q+  + +  +GA + +T ++ V   +P+P  +VK  
Sbjct  67   VDYTFEGDNTVSWHLVESGQQNA-QDGSYVLTESGAGTKVTFELTVDPKIPLPGFLVKKA  125

Query  140  LNNVLEHLAENLKQRAEQL  158
                LE  ++ L +  E L
Sbjct  126  QKTALETASKGLTKFVESL  144


>gi|111023701|ref|YP_706673.1| hypothetical protein RHA1_ro06743 [Rhodococcus jostii RHA1]
 gi|110823231|gb|ABG98515.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=144

 Score = 71.6 bits (174),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 39/139 (29%), Positives = 76/139 (55%), Gaps = 2/139 (1%)

Query  21   KTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYI  80
            K  E+ AD A++MA +A ++R PEW+   K   + + +DDGRP +VR+  ++ GI    +
Sbjct  7    KEFEIKADPATVMAAIAAVDRLPEWSSAHKSVTIESTHDDGRPHRVRMSVSILGISDEQV  66

Query  81   HAVYYPGENQIQ-TVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
                + G++ +   +++ G+  A Q+  + +  +GA + +T ++ V   +P+P  +VK  
Sbjct  67   VDYTFEGDDTVSWHLVESGQQNA-QDGSYVLTESGAGTKVTFELTVDPKIPLPGFLVKKA  125

Query  140  LNNVLEHLAENLKQRAEQL  158
                LE  ++ L +  E L
Sbjct  126  QKTALETASKGLTKFVESL  144


>gi|118465100|ref|YP_880235.1| cyclase/dehydrase [Mycobacterium avium 104]
 gi|118166387|gb|ABK67284.1| cyclase/dehydrase superfamily protein [Mycobacterium avium 104]
Length=147

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 39/135 (29%), Positives = 70/135 (52%), Gaps = 1/135 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ + + A    I+ ++AD E  P+W+E  + A VLA  DDGRPSQVR+   V GI    
Sbjct  6    SRDIVIEASPEEILDVIADFESMPQWSEPHQSAEVLATGDDGRPSQVRMKVKVAGITDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            + A Y   +N +   +        Q+  +++V  G A+L+  ++     +P+P  ++K  
Sbjct  66   VVA-YTWADNVVSWTLVSSSQQKAQDGKYTLVPQGDATLVKFELVADPNVPLPGFVLKRA  124

Query  140  LNNVLEHLAENLKQR  154
            +   ++   + L+QR
Sbjct  125  VKGTIDSATKALRQR  139


>gi|240171441|ref|ZP_04750100.1| hypothetical protein MkanA1_19161 [Mycobacterium kansasii ATCC 
12478]
Length=147

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 37/135 (28%), Positives = 69/135 (52%), Gaps = 1/135 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ V + A    I+ +VADIE  PEW++  + A VL R+DDGRP + R+     G+    
Sbjct  6    SREVVIEASPKEILDVVADIEAMPEWSDIHQSAQVLERHDDGRPRRARMKVKTAGVTDEI  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            + A Y   ++ +    + G+    QE  +++   G  +    D+ +   +P+P  ++K  
Sbjct  66   VLA-YTWRDDGVTWTQESGKASRNQEGGYTLTPEGDKTRTKFDLSLDPLVPLPGFVIKRA  124

Query  140  LNNVLEHLAENLKQR  154
            +  V+E   + L++R
Sbjct  125  IKGVIEINTDGLRKR  139


>gi|291450893|ref|ZP_06590283.1| cyclase/dehydrase [Streptomyces albus J1074]
 gi|291353842|gb|EFE80744.1| cyclase/dehydrase [Streptomyces albus J1074]
Length=148

 Score = 64.7 bits (156),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 41/141 (30%), Positives = 72/141 (52%), Gaps = 7/141 (4%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +MA++AD  RYPEW   VK A VLA  D GR  QVRL      I+  +
Sbjct  6    SSSITIDAAPAEVMAVIADFARYPEWTGEVKEADVLATDDQGRAEQVRLVLDAGAIKDDH  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
              A  + G +Q++  + + ++  + +  +++ A G       ++  Q+T+ V  PM+ M+
Sbjct  66   TLAYTWHGPDQVRWTLVKSQMLRELDGSYTLAALGEGR---TEVTYQLTVDVKIPMLGMI  122

Query  140  LNN----VLEHLAENLKQRAE  156
                   +++     LK+R E
Sbjct  123  KRKAEKVIIDRALAGLKKRVE  143


>gi|226306216|ref|YP_002766176.1| hypothetical protein RER_27290 [Rhodococcus erythropolis PR4]
 gi|226185333|dbj|BAH33437.1| conserved hypothetical protein [Rhodococcus erythropolis PR4]
Length=144

 Score = 64.3 bits (155),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 33/138 (24%), Positives = 69/138 (50%), Gaps = 0/138 (0%)

Query  21   KTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYI  80
            K  E+ AD  ++M  VA ++R PEW+   K   + + +DDGRP +VR+  ++ GI    +
Sbjct  7    KEFEIKADPETVMKAVAAVDRLPEWSSAHKKITIESTHDDGRPHRVRMAVSILGINDEQV  66

Query  81   HAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLL  140
                + G++++   + +     +Q+  + +  T   + +T ++ +   +P+P  +VK   
Sbjct  67   VDYTFEGDDKVTWTLVESGQQNQQDGSYVLTPTDGGTKVTFELTIDPKIPLPGFLVKKAQ  126

Query  141  NNVLEHLAENLKQRAEQL  158
               LE  ++ L +  E  
Sbjct  127  KTALETASKGLTKFVENF  144


>gi|229490868|ref|ZP_04384703.1| cyclase/dehydrase [Rhodococcus erythropolis SK121]
 gi|229322258|gb|EEN88044.1| cyclase/dehydrase [Rhodococcus erythropolis SK121]
Length=144

 Score = 63.5 bits (153),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 33/138 (24%), Positives = 68/138 (50%), Gaps = 0/138 (0%)

Query  21   KTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYI  80
            K  E+ AD  ++M  VA ++R PEW+   K   + + +DDGRP +VR+  ++ GI    +
Sbjct  7    KEFEIKADPETVMKAVAAVDRLPEWSSAHKKITIESTHDDGRPHRVRMAVSILGINDEQV  66

Query  81   HAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLL  140
                + G+ ++   + +     +Q+  + +  T   + +T ++ +   +P+P  +VK   
Sbjct  67   VDYTFEGDEKVTWTLVESGQQNQQDGSYVLTPTDGGTKVTFELTIDPKIPLPGFLVKKAQ  126

Query  141  NNVLEHLAENLKQRAEQL  158
               LE  ++ L +  E  
Sbjct  127  KTALETASKGLTKFVENF  144


>gi|120406021|ref|YP_955850.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1]
 gi|119958839|gb|ABM15844.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1]
Length=156

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 33/135 (25%), Positives = 69/135 (52%), Gaps = 1/135 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ V + A    I+ ++AD+E  P W+   + A +L RYD+GRP QVR+     G+    
Sbjct  16   SREVVIEATPEQILDVIADVEATPTWSPQYQKAEILDRYDNGRPKQVRMTVKAAGLTDEQ  75

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            +   Y  G+N++   +        Q+  +++   G  + +  D+ + +++P+P  ++K  
Sbjct  76   VIE-YTWGDNEVSWTLVSATQLKAQDAGYTLTPAGDKTKVKFDIAIDLSVPLPGFIIKRT  134

Query  140  LNNVLEHLAENLKQR  154
            +   +E   E L+++
Sbjct  135  IKGGVETATEGLRKQ  149


>gi|239987099|ref|ZP_04707763.1| hypothetical protein SrosN1_07317 [Streptomyces roseosporus NRRL 
11379]
 gi|291444054|ref|ZP_06583444.1| cyclase/dehydrase [Streptomyces roseosporus NRRL 15998]
 gi|291347001|gb|EFE73905.1| cyclase/dehydrase [Streptomyces roseosporus NRRL 15998]
Length=149

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 38/139 (28%), Positives = 71/139 (52%), Gaps = 2/139 (1%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +M ++AD  RYPEW   VK A VL+  D GR  QVRL      I+  +
Sbjct  6    SSSITIEAAPADVMGVIADFARYPEWTGEVKEAEVLSTDDQGRAEQVRLVLDAGAIKDDH  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSV--VATGAASLLTVDMDVQVTMPVPEPMVK  137
            + A  + GEN++   + + ++    +  +++  +A G  + +T  + V V +P+   + +
Sbjct  66   VLAYTWTGENEVSWSLVKSQMLRSLDGTYALTPLAGGERTEVTYRLAVDVKIPLLGMIKR  125

Query  138  MLLNNVLEHLAENLKQRAE  156
                 +++     LK+R E
Sbjct  126  KAEKVIIDRALAGLKKRVE  144


>gi|41406882|ref|NP_959718.1| hypothetical protein MAP0784 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41395232|gb|AAS03101.1| hypothetical protein MAP_0784 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336461196|gb|EGO40072.1| Polyketide cyclase / dehydrase and lipid transport [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=147

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 38/135 (29%), Positives = 69/135 (52%), Gaps = 1/135 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ + + A    I+ ++AD E  P+W+E  + A VLA   DGRPSQVR+   V GI    
Sbjct  6    SRDIVIEASPEEILDVIADFESMPQWSEPHQSAEVLATGHDGRPSQVRMKVKVAGITDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            + A Y   +N +   +        Q+  +++V  G A+L+  ++     +P+P  ++K  
Sbjct  66   VVA-YTWADNVVSWTLVSSSQQKAQDGKYTLVPQGDATLVKFELVADPNVPLPGFVLKRA  124

Query  140  LNNVLEHLAENLKQR  154
            +   ++   + L+QR
Sbjct  125  VKGTIDSATKALRQR  139


>gi|111018708|ref|YP_701680.1| hypothetical protein RHA1_ro01709 [Rhodococcus jostii RHA1]
 gi|110818238|gb|ABG93522.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=146

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 36/119 (31%), Positives = 63/119 (53%), Gaps = 0/119 (0%)

Query  19   LSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT  78
            +S   E+ A    +MA +AD+ER PEW+   K   V +R+DDGRP  VR+  AV G+  T
Sbjct  5    VSGEFEIEAPQDQVMAALADVERIPEWSAVHKKVVVESRFDDGRPRTVRMTLAVLGVADT  64

Query  79   YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVK  137
             +    + G+ Q+   + + E    QE  + +  T   + + + M V+  + VP+ +++
Sbjct  65   QLAEHKWLGDEQMSWTLLESEKQKCQEGEYRLTPTARGTSVHLTMSVEPKVWVPKSVLR  123


>gi|328881837|emb|CCA55076.1| hypothetical protein SVEN_1789 [Streptomyces venezuelae ATCC 
10712]
Length=145

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 37/140 (27%), Positives = 67/140 (48%), Gaps = 0/140 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +M ++AD  RYPEW   VK A VL   D GR  +VRL      I+  +
Sbjct  6    SSSITIEAAPADVMGVIADFARYPEWTGEVKEAEVLETDDSGRAEKVRLLLDAGAIKDDH  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
              A  + G N++   + + ++    +  + + A G  + +T  + V V +P+   + +  
Sbjct  66   TLAYTWTGANEVSWTLVKSQMLRSLDGSYRLTAVGDRTEVTYQLTVDVKIPMLGMIKRKA  125

Query  140  LNNVLEHLAENLKQRAEQLA  159
               +++     LK+R E  A
Sbjct  126  EKVIIDRALAGLKKRVESAA  145


>gi|297161241|gb|ADI10953.1| hypothetical protein SBI_07833 [Streptomyces bingchenggensis 
BCW-1]
Length=147

 Score = 61.2 bits (147),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 38/142 (27%), Positives = 71/142 (50%), Gaps = 2/142 (1%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +M ++AD +RYPEW+  VK A VL + D GR  +VR+      I+  Y
Sbjct  6    SSSITIEAAPADVMEVIADFDRYPEWSGEVKEADVLTKDDRGRAEKVRMLLDAGAIKDDY  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQE--QLFSVVATGAASLLTVDMDVQVTMPVPEPMVK  137
                 + G+NQ+   + + ++    +   L + V +G  + +T  + V V +P+   + +
Sbjct  66   TLEYTWTGDNQVSWSLVKSQMLRSLDGSYLLAPVDSGKRTEVTYQLTVDVKIPMLGMIKR  125

Query  138  MLLNNVLEHLAENLKQRAEQLA  159
                 +++     LK+R E  A
Sbjct  126  KAEKVIIDRALAGLKKRVESAA  147


>gi|182439167|ref|YP_001826886.1| hypothetical protein SGR_5374 [Streptomyces griseus subsp. griseus 
NBRC 13350]
 gi|326779819|ref|ZP_08239084.1| cyclase/dehydrase [Streptomyces cf. griseus XylebKG-1]
 gi|178467683|dbj|BAG22203.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus 
NBRC 13350]
 gi|326660152|gb|EGE44998.1| cyclase/dehydrase [Streptomyces griseus XylebKG-1]
Length=149

 Score = 61.2 bits (147),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 37/140 (27%), Positives = 71/140 (51%), Gaps = 2/140 (1%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +M+++AD  RYPEW   VK A VL+  D GR  QVRL      I+  +
Sbjct  6    SSSITIEAAPADVMSVIADFARYPEWTGEVKEAEVLSTDDRGRAEQVRLVLDAGAIKDDH  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSV--VATGAASLLTVDMDVQVTMPVPEPMVK  137
            + A  + GEN++   + + ++    +  +++  +  G  + +T  + V V +P+   + +
Sbjct  66   VLAYTWNGENEVSWSLVKSQMLRSLDGTYALAPLGGGERTEVTYRLAVDVKIPLLGMIKR  125

Query  138  MLLNNVLEHLAENLKQRAEQ  157
                 +++     LK+R E 
Sbjct  126  KAEKVIIDRALAGLKKRVES  145


>gi|345014505|ref|YP_004816859.1| cyclase/dehydrase [Streptomyces violaceusniger Tu 4113]
 gi|344040854|gb|AEM86579.1| cyclase/dehydrase [Streptomyces violaceusniger Tu 4113]
Length=146

 Score = 60.5 bits (145),  Expect = 9e-08, Method: Compositional matrix adjust.
 Identities = 36/141 (26%), Positives = 70/141 (50%), Gaps = 6/141 (4%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +M ++AD +RYPEW+  VK A +L + D GR  QVR+      I+  Y
Sbjct  6    SSSITIEAAPADVMEVIADFDRYPEWSGEVKEADILTKDDRGRAEQVRMLLDAGAIKDDY  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
                 + G++Q+   + + ++    +  + + A       + ++  Q+T+ V  PM+ M+
Sbjct  66   TLQYSWTGDDQVNWSLVKSQMLRTLDGSYRLSARDGGK--STEVTYQLTVDVKIPMLGMI  123

Query  140  LNN----VLEHLAENLKQRAE  156
                   +++     LK+R E
Sbjct  124  KRKAEKVIIDRALAGLKKRVE  144


>gi|111219669|ref|YP_710463.1| hypothetical protein FRAAL0171 [Frankia alni ACN14a]
 gi|111147201|emb|CAJ58850.1| conserved hypothetical protein; putative cyclase/dehydrase domains 
[Frankia alni ACN14a]
Length=144

 Score = 60.5 bits (145),  Expect = 9e-08, Method: Compositional matrix adjust.
 Identities = 36/140 (26%), Positives = 71/140 (51%), Gaps = 1/140 (0%)

Query  19   LSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGT  78
            +S T+ + A  A+I+A++ADI RYP+W+E VK A V+     G P++ R        +  
Sbjct  5    VSSTIVIKAQPAAILAVIADISRYPDWSEPVKSAEVIETTPAGLPAKARFQAKTTFGKED  64

Query  79   YIHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASL-LTVDMDVQVTMPVPEPMVK  137
            Y     + G N +   M + +     +  +++   G  S  +T D+ V++ +P+P  + +
Sbjct  65   YALVYDWVGPNSVTWTMLESDRVRTLDGSYTLTDLGDGSTEVTYDLTVELKVPIPGLLRR  124

Query  138  MLLNNVLEHLAENLKQRAEQ  157
               + ++E    +LK + E+
Sbjct  125  KAEDKLVESALYDLKTQVER  144


>gi|108801463|ref|YP_641660.1| cyclase/dehydrase [Mycobacterium sp. MCS]
 gi|119870616|ref|YP_940568.1| cyclase/dehydrase [Mycobacterium sp. KMS]
 gi|126437448|ref|YP_001073139.1| cyclase/dehydrase [Mycobacterium sp. JLS]
 gi|108771882|gb|ABG10604.1| cyclase/dehydrase [Mycobacterium sp. MCS]
 gi|119696705|gb|ABL93778.1| cyclase/dehydrase [Mycobacterium sp. KMS]
 gi|126237248|gb|ABO00649.1| cyclase/dehydrase [Mycobacterium sp. JLS]
Length=148

 Score = 60.5 bits (145),  Expect = 9e-08, Method: Compositional matrix adjust.
 Identities = 35/140 (25%), Positives = 72/140 (52%), Gaps = 1/140 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ V + A  A I+ ++AD+E  P W+   + A +L  Y DGRP QV++     GI    
Sbjct  6    SREVVIEATPAQILDVIADVEATPSWSPQYQSAEILDTYADGRPRQVKMKVKSAGITDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            +    +       T++  G+L A Q+  +++   G  + +  D+ V +++P+P  ++K  
Sbjct  66   VIEYTWTDSKVSWTLVSAGQLKA-QDASYTLTPDGEKTKVRFDIKVDLSVPLPGFVLKRA  124

Query  140  LNNVLEHLAENLKQRAEQLA  159
            +   +E   + L+++  ++A
Sbjct  125  MKGAMETATDGLRKQVLKVA  144


>gi|254818313|ref|ZP_05223314.1| cyclase/dehydrase superfamily protein [Mycobacterium intracellulare 
ATCC 13950]
Length=147

 Score = 60.1 bits (144),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 35/135 (26%), Positives = 67/135 (50%), Gaps = 1/135 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ + + A    I+ ++AD E  PEW+E  + A VL   DDGRP QVR+   V GI    
Sbjct  6    SRDIVIEASPEEILDVIADFESMPEWSEPHQSAEVLETGDDGRPRQVRMRVKVAGITDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            + A Y   +N +   +        Q+  ++++  G  +L+  ++     +P+P  ++K  
Sbjct  66   VVA-YTWADNAVSWTLVSSSQQKAQDGKYTLIPQGDKTLVKFELLADPNVPLPGFVLKRA  124

Query  140  LNNVLEHLAENLKQR  154
            +   ++   + L++R
Sbjct  125  VKGTIDSATKALRER  139


>gi|145222270|ref|YP_001132948.1| cyclase/dehydrase [Mycobacterium gilvum PYR-GCK]
 gi|145214756|gb|ABP44160.1| cyclase/dehydrase [Mycobacterium gilvum PYR-GCK]
Length=146

 Score = 60.1 bits (144),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 32/139 (24%), Positives = 71/139 (52%), Gaps = 1/139 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ V + A    I+ ++AD+E  P W+   + A VL R+D+GRP QV++     G+    
Sbjct  6    SREVVIEATPEQILDVIADVEATPTWSPQYQKAEVLERFDNGRPKQVKMTVKAAGLTDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            +   Y  G++++   +        Q+  +++   G  + +  D+ + +++P+P  ++K  
Sbjct  66   VIE-YTWGDDRVTWTLVSASQLKAQDAGYTLTPEGDKTRVRFDIAIDLSVPLPGFLLKRT  124

Query  140  LNNVLEHLAENLKQRAEQL  158
            +   +E   E LK++  ++
Sbjct  125  MKGGVETATEGLKKQVHKV  143


>gi|315442701|ref|YP_004075580.1| polyketide cyclase / dehydrase family protein [Mycobacterium 
sp. Spyr1]
 gi|315261004|gb|ADT97745.1| polyketide cyclase / dehydrase family protein [Mycobacterium 
sp. Spyr1]
Length=146

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 32/139 (24%), Positives = 71/139 (52%), Gaps = 1/139 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ V + A    I+ ++AD+E  P W+   + A VL R+D+GRP QV++     G+    
Sbjct  6    SREVVIEATPEQILDVIADVEATPTWSPQYQKAEVLDRFDNGRPKQVKMTVKAAGLTDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            +   Y  G++++   +        Q+  +++   G  + +  D+ + +++P+P  ++K  
Sbjct  66   VIE-YTWGDDRVTWTLVSASQLKAQDAGYTLTPEGDKTRVRFDIAIDLSVPLPGFLLKRT  124

Query  140  LNNVLEHLAENLKQRAEQL  158
            +   +E   E LK++  ++
Sbjct  125  MKGGVETATEGLKKQVHKV  143


>gi|331696583|ref|YP_004332822.1| cyclase/dehydrase [Pseudonocardia dioxanivorans CB1190]
 gi|326951272|gb|AEA24969.1| cyclase/dehydrase [Pseudonocardia dioxanivorans CB1190]
Length=144

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 36/139 (26%), Positives = 71/139 (52%), Gaps = 2/139 (1%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            + ++ + AD   +MA++AD E YP+W E VK   +L    DGR  +VR       I+ +Y
Sbjct  6    TSSISIAADPQRVMAVIADFEAYPKWAEQVKTVEILDEA-DGRARRVRFTMDAGPIKDSY  64

Query  80   -IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKM  138
             +   + P  N +   + +G++   Q   + +VA G ++ +T  + V + +P+   + + 
Sbjct  65   TLDYDWAPDGNSVSWNLVKGQMQKSQNGSYVLVADGDSTTVTYSLAVDLNIPMIGMLRRK  124

Query  139  LLNNVLEHLAENLKQRAEQ  157
                +++   + LK+R EQ
Sbjct  125  AEKVIIDTALKGLKRRVEQ  143


>gi|297199107|ref|ZP_06916504.1| cyclase/dehydrase [Streptomyces sviceus ATCC 29083]
 gi|197715175|gb|EDY59209.1| cyclase/dehydrase [Streptomyces sviceus ATCC 29083]
Length=146

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 39/142 (28%), Positives = 70/142 (50%), Gaps = 9/142 (6%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +MA++AD  RYP+W   VK A VL+    GR  QVRL      I+   
Sbjct  6    SSSITIEAAPADVMAVIADFARYPDWTGEVKQAEVLSTDASGRAEQVRLVMDAGAIKDDQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAAS-----LLTVDMDVQVTMPVPEP  134
            +    + GEN++   + + ++  + +  + +   GA +     LLTVD+ + +   +   
Sbjct  66   VLGYTWTGENEVSWTLVKSQMLRQLDGSYVLKPAGAGATEVTYLLTVDVKIPMLGMIKRK  125

Query  135  MVKMLLNNVLEHLAENLKQRAE  156
              K++++  L      LK+R E
Sbjct  126  AEKVIIDRAL----AGLKKRVE  143


>gi|342860457|ref|ZP_08717108.1| cyclase/dehydrase [Mycobacterium colombiense CECT 3035]
 gi|342132112|gb|EGT85353.1| cyclase/dehydrase [Mycobacterium colombiense CECT 3035]
Length=147

 Score = 58.9 bits (141),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 36/139 (26%), Positives = 69/139 (50%), Gaps = 1/139 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ + + A    I+ ++AD E  PEW+E  + A +L   DDGRP QVR+   V GI    
Sbjct  6    SRDIVIEASPEEILDVIADFEAMPEWSEPHQSAEILDTGDDGRPRQVRMKVRVAGITDEQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            + A Y  G+N +   +        Q+  +++V     +L+  ++     +P+P  ++K  
Sbjct  66   VIA-YTWGDNVVSWKLVSSSQQKAQDGKYTLVPQDNGTLVKFELLADPNVPLPGFVLKRA  124

Query  140  LNNVLEHLAENLKQRAEQL  158
            +   ++   + L++R  Q+
Sbjct  125  VKGTIDSATKALRERVLQV  143


>gi|256375524|ref|YP_003099184.1| cyclase/dehydrase [Actinosynnema mirum DSM 43827]
 gi|255919827|gb|ACU35338.1| cyclase/dehydrase [Actinosynnema mirum DSM 43827]
Length=144

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 40/137 (30%), Positives = 66/137 (49%), Gaps = 3/137 (2%)

Query  22   TVEVTADAA--SIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            T  +  DAA   I+A++AD + YPEW  GVK   VL R DDGR ++V        I+  Y
Sbjct  6    TQSIVIDAAPEQILAVIADFDSYPEWANGVKQTEVLKRDDDGRATEVEFAIDQGPIKDDY  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
            +   Y      +   + +G +   QE  + +  TGA   +T  + VQ+ +P+     +  
Sbjct  66   VLG-YTWRPTGVSWTLLKGTMQKAQEGSYELTPTGAGVQVTYTLSVQLVVPMIGLFRRKA  124

Query  140  LNNVLEHLAENLKQRAE  156
               +++   + LK+R E
Sbjct  125  EKVIMDTALKELKRRVE  141


>gi|254393052|ref|ZP_05008214.1| cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064]
 gi|294812180|ref|ZP_06770823.1| Cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064]
 gi|326440664|ref|ZP_08215398.1| hypothetical protein SclaA2_06338 [Streptomyces clavuligerus 
ATCC 27064]
 gi|197706701|gb|EDY52513.1| cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064]
 gi|294324779|gb|EFG06422.1| Cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064]
Length=149

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 36/142 (26%), Positives = 68/142 (48%), Gaps = 6/142 (4%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +M +++D +RYPEW   VK A VL+R + GR  QVRL      I+  +
Sbjct  6    SSSITIEAAPADVMGVISDFDRYPEWTGEVKQAEVLSRDEQGRAEQVRLVLDAGAIKDDH  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
              A  + G + +   + + ++    +  +++   G      V     +T+ V  PM+ M+
Sbjct  66   TLAYSWEGADTVSWTLVKSQMLRALDGSYTLAPVGGGDRTEVTY--TLTVDVKIPMLGMI  123

Query  140  LNN----VLEHLAENLKQRAEQ  157
                   +++   + LK+R E 
Sbjct  124  KRKAEKVIIDRALDGLKKRVEN  145


>gi|118471284|ref|YP_889969.1| cyclase/dehydrase [Mycobacterium smegmatis str. MC2 155]
 gi|118172571|gb|ABK73467.1| cyclase/dehydrase [Mycobacterium smegmatis str. MC2 155]
Length=146

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 34/136 (25%), Positives = 71/136 (53%), Gaps = 3/136 (2%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S+ V + A    I+ ++AD+E  P W+     A +  RYDDGRP + ++     G+    
Sbjct  6    SREVLIEASPEEILDVIADVESTPSWSPQYTHAEITERYDDGRPRRAKMTVKAAGLTDDQ  65

Query  80   IHAVYYPGENQIQ-TVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKM  138
            +   Y   EN++  T++  G+L A Q+  +++   G  + +  D+ + +++P+P  +VK 
Sbjct  66   VIE-YTWSENKVSWTLVSAGQLKA-QDASYTLTPQGDKTKVRFDISIDLSVPLPGFIVKR  123

Query  139  LLNNVLEHLAENLKQR  154
             +   +E   + L+++
Sbjct  124  TMKGGVETATDGLRKQ  139


>gi|319950670|ref|ZP_08024571.1| cyclase/dehydrase [Dietzia cinnamea P4]
 gi|319435653|gb|EFV90872.1| cyclase/dehydrase [Dietzia cinnamea P4]
Length=153

 Score = 58.5 bits (140),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 37/141 (27%), Positives = 67/141 (48%), Gaps = 2/141 (1%)

Query  17   PVLSKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIE  76
            P    TV V A  A +MA++AD   YPEW+  +  A VL+   DGRP +VR       I 
Sbjct  12   PTRDSTV-VDASVADVMAVIADFAAYPEWSASIDAAEVLSTGADGRPDRVRFQLRAGAIV  70

Query  77   GTYIHAVYYPGENQ-IQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPM  135
              Y+    +  +++ ++  ++   L   Q   + +    A + +  ++++++T+PV   +
Sbjct  71   DEYVLVYSWSADHRSVEWRLESSTLQRDQRGSYRLEPVEAGTRVDYELEIELTVPVIGSL  130

Query  136  VKMLLNNVLEHLAENLKQRAE  156
                   +L      LK+RAE
Sbjct  131  RSRAQRRILGDALSELKRRAE  151


>gi|21220606|ref|NP_626385.1| hypothetical protein SCO2129 [Streptomyces coelicolor A3(2)]
 gi|289772146|ref|ZP_06531524.1| cyclase/dehydrase [Streptomyces lividans TK24]
 gi|4539198|emb|CAB39856.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]
 gi|289702345|gb|EFD69774.1| cyclase/dehydrase [Streptomyces lividans TK24]
Length=144

 Score = 57.8 bits (138),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 35/137 (26%), Positives = 66/137 (49%), Gaps = 0/137 (0%)

Query  20   SKTVEVTADAASIMAIVADIERYPEWNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTY  79
            S ++ + A  A +MA++AD  RYP+W   VK A VLA  + GR  QVRL      I+   
Sbjct  6    SSSITIEAAPADVMAVIADFARYPDWTGEVKEAQVLATDEQGRAEQVRLVMDAGAIKDDQ  65

Query  80   IHAVYYPGENQIQTVMQQGELFAKQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKML  139
                 + GE+++   + + ++    +  + +   G  + +T  + V V +P+   + +  
Sbjct  66   TLGYTWTGEHEVSWTLVKSQMLRSLDGSYLLRPAGTGTEVTYRLTVDVKIPMLGMIKRKA  125

Query  140  LNNVLEHLAENLKQRAE  156
               +++     LK+R E
Sbjct  126  EKVIIDRALAGLKKRVE  142



Lambda     K      H
   0.316    0.129    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 131112251088




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40