BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0196 Length=194 Score E Sequences producing significant alignments: (Bits) Value gi|15607337|ref|NP_214710.1| transcriptional regulatory protein ... 387 6e-106 gi|340625233|ref|YP_004743685.1| putative transcriptional regula... 384 5e-105 gi|289568097|ref|ZP_06448324.1| transcriptional regulator [Mycob... 381 3e-104 gi|183980467|ref|YP_001848758.1| transcriptional regulatory prot... 313 7e-84 gi|240172082|ref|ZP_04750741.1| transcriptional regulatory prote... 307 6e-82 gi|296167413|ref|ZP_06849814.1| transcriptional regulatory prote... 304 5e-81 gi|118616816|ref|YP_905148.1| transcriptional regulatory protein... 299 1e-79 gi|342859348|ref|ZP_08716002.1| TetR family transcriptional regu... 293 9e-78 gi|254819020|ref|ZP_05224021.1| putative transcriptional regulat... 289 1e-76 gi|118463812|ref|YP_884106.1| TetR family transcriptional regula... 286 1e-75 gi|41409733|ref|NP_962569.1| hypothetical protein MAP3635 [Mycob... 285 2e-75 gi|169628585|ref|YP_001702234.1| TetR family transcriptional reg... 241 3e-62 gi|145223874|ref|YP_001134552.1| TetR family transcriptional reg... 238 3e-61 gi|315444203|ref|YP_004077082.1| TetR family transcriptional reg... 238 3e-61 gi|126435330|ref|YP_001071021.1| TetR family transcriptional reg... 236 1e-60 gi|108799686|ref|YP_639883.1| TetR family transcriptional regula... 236 1e-60 gi|118468501|ref|YP_887823.1| TetR family transcriptional regula... 232 3e-59 gi|120403991|ref|YP_953820.1| TetR family transcriptional regula... 226 2e-57 gi|269127158|ref|YP_003300528.1| TetR family transcriptional reg... 162 2e-38 gi|117164804|emb|CAJ88353.1| putative TetR-family transcriptiona... 154 9e-36 gi|126432819|ref|YP_001068510.1| TetR family transcriptional reg... 149 2e-34 gi|120401301|ref|YP_951130.1| TetR family transcriptional regula... 148 5e-34 gi|302544751|ref|ZP_07297093.1| putative transcriptional regulat... 145 2e-33 gi|297159014|gb|ADI08726.1| transcriptional regulator, TetR fami... 144 5e-33 gi|300786219|ref|YP_003766510.1| TetR family transcriptional reg... 141 5e-32 gi|325675978|ref|ZP_08155661.1| TetR family transcriptional regu... 141 5e-32 gi|262200728|ref|YP_003271936.1| TetR family transcriptional reg... 137 7e-31 gi|134099489|ref|YP_001105150.1| TetR family transcriptional reg... 136 1e-30 gi|329937018|ref|ZP_08286647.1| TetR family transcriptional regu... 135 4e-30 gi|312140412|ref|YP_004007748.1| tetr family transcriptional reg... 134 5e-30 gi|312197309|ref|YP_004017370.1| TetR family transcriptional reg... 134 8e-30 gi|342859315|ref|ZP_08715969.1| TetR family transcriptional regu... 134 8e-30 gi|343925713|ref|ZP_08765228.1| putative TetR family transcripti... 133 1e-29 gi|118616842|ref|YP_905174.1| transcriptional regulatory protein... 133 2e-29 gi|291435352|ref|ZP_06574742.1| TetR-family protein transcriptio... 132 2e-29 gi|240168440|ref|ZP_04747099.1| transcriptional regulatory prote... 132 3e-29 gi|183980499|ref|YP_001848790.1| transcriptional regulatory prot... 132 3e-29 gi|284047122|ref|YP_003397462.1| TetR family transcriptional reg... 131 4e-29 gi|296167451|ref|ZP_06849850.1| TetR family transcriptional regu... 130 7e-29 gi|118467192|ref|YP_884069.1| TetR family transcriptional regula... 130 7e-29 gi|41409759|ref|NP_962595.1| hypothetical protein MAP3661c [Myco... 130 1e-28 gi|254822658|ref|ZP_05227659.1| transcriptional regulator, TetR ... 130 1e-28 gi|297196674|ref|ZP_06914072.1| TetR family transcriptional regu... 128 4e-28 gi|239820822|ref|YP_002948007.1| transcriptional regulator, TetR... 126 1e-27 gi|258651043|ref|YP_003200199.1| TetR family transcriptional reg... 126 1e-27 gi|318057765|ref|ZP_07976488.1| TetR family transcriptional regu... 125 3e-27 gi|302555869|ref|ZP_07308211.1| TetR family transcriptional regu... 125 3e-27 gi|333919608|ref|YP_004493189.1| TetR family transcriptional reg... 125 3e-27 gi|29833709|ref|NP_828343.1| TetR family transcriptional regulat... 125 4e-27 gi|302540382|ref|ZP_07292724.1| putative transcriptional regulat... 124 8e-27 >gi|15607337|ref|NP_214710.1| transcriptional regulatory protein [Mycobacterium tuberculosis H37Rv] gi|15839576|ref|NP_334613.1| transcriptional regulator, putative [Mycobacterium tuberculosis CDC1551] gi|31791374|ref|NP_853867.1| putative transcriptional regulatory protein [Mycobacterium bovis AF2122/97] 77 more sequence titles Length=194 Score = 387 bits (993), Expect = 6e-106, Method: Compositional matrix adjust. Identities = 194/194 (100%), Positives = 194/194 (100%), Gaps = 0/194 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA Sbjct 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ Sbjct 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 Query 181 LRNLLLAELPERSR 194 LRNLLLAELPERSR Sbjct 181 LRNLLLAELPERSR 194 >gi|340625233|ref|YP_004743685.1| putative transcriptional regulatory protein [Mycobacterium canettii CIPT 140010059] gi|340003423|emb|CCC42543.1| putative transcriptional regulatory protein [Mycobacterium canettii CIPT 140010059] Length=194 Score = 384 bits (985), Expect = 5e-105, Method: Compositional matrix adjust. Identities = 193/194 (99%), Positives = 193/194 (99%), Gaps = 0/194 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA Sbjct 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRD TPLDLVHRQ Sbjct 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDPTPLDLVHRQ 180 Query 181 LRNLLLAELPERSR 194 LRNLLLAELPERSR Sbjct 181 LRNLLLAELPERSR 194 >gi|289568097|ref|ZP_06448324.1| transcriptional regulator [Mycobacterium tuberculosis T17] gi|289541850|gb|EFD45499.1| transcriptional regulator [Mycobacterium tuberculosis T17] Length=203 Score = 381 bits (979), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 192/193 (99%), Positives = 192/193 (99%), Gaps = 0/193 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA Sbjct 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ Sbjct 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 Query 181 LRNLLLAELPERS 193 LRNLLLAELPE S Sbjct 181 LRNLLLAELPEPS 193 >gi|183980467|ref|YP_001848758.1| transcriptional regulatory protein [Mycobacterium marinum M] gi|183173793|gb|ACC38903.1| transcriptional regulatory protein [Mycobacterium marinum M] Length=198 Score = 313 bits (803), Expect = 7e-84, Method: Compositional matrix adjust. Identities = 154/194 (80%), Positives = 171/194 (89%), Gaps = 0/194 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMV+SA LLIRERGA ATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MPSPRERMVISAVLLIRERGARATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 HVA +I A L+LLD LID+YR+QL +TDFRAGCP+AAVSVEAG+ DRERMAPV+ Sbjct 61 AHVAKIIGSANRSLDLLDTLIDQYREQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 AAAVFDRWSDL AQRF++DGIP D AHELAV A STLEGA+LLARVRRDLTPLD+VHRQ Sbjct 121 HAAAVFDRWSDLIAQRFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLDVVHRQ 180 Query 181 LRNLLLAELPERSR 194 LR++LLA+LPE +R Sbjct 181 LRSMLLAQLPEGNR 194 >gi|240172082|ref|ZP_04750741.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=195 Score = 307 bits (786), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 155/191 (82%), Positives = 167/191 (88%), Gaps = 0/191 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M GPRERMVVSAALLIRERGA ATAI+DVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MPGPRERMVVSAALLIRERGARATAIADVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 EHVAA+I E LELLD LI KYR+QLL++DFRAGCPIAAV+VEAG+ D ERM PVI Sbjct 61 EHVAAIITEPRDSLELLDTLIGKYREQLLASDFRAGCPIAAVAVEAGEGPDSERMTPVIE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 AAAVFDRWS L AQRF+ DGIP RA+ELAV ATS LEGA+LLARVRRDLTPL+ VHRQ Sbjct 121 HAAAVFDRWSALIAQRFVGDGIPAGRANELAVFATSALEGALLLARVRRDLTPLESVHRQ 180 Query 181 LRNLLLAELPE 191 L +LLLAELPE Sbjct 181 LHHLLLAELPE 191 >gi|296167413|ref|ZP_06849814.1| transcriptional regulatory protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897222|gb|EFG76827.1| transcriptional regulatory protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=193 Score = 304 bits (778), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 150/188 (80%), Positives = 171/188 (91%), Gaps = 3/188 (1%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M+ PRERMV+SAALLIRERGAHATAISDVL+HSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MRSPRERMVISAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 EHVAA+I +AE G EL+D LIDKYR+QLL +DFRAGCP+ AVSVEAG+E ERMAPV+ Sbjct 61 EHVAAVIADAESGPELMDTLIDKYRRQLLDSDFRAGCPVVAVSVEAGEE---ERMAPVVE 117 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAA+VFDRW+DL AQRF+ADGIP +RA +LA+LAT+ LEGAI+LARVRRDL PLD+VHRQ Sbjct 118 RAASVFDRWTDLIAQRFVADGIPRERAGDLAMLATTALEGAIVLARVRRDLAPLDVVHRQ 177 Query 181 LRNLLLAE 188 LR+LL AE Sbjct 178 LRDLLAAE 185 >gi|118616816|ref|YP_905148.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] gi|118568926|gb|ABL03677.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] Length=191 Score = 299 bits (765), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 148/187 (80%), Positives = 165/187 (89%), Gaps = 0/187 (0%) Query 8 MVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMI 67 MV+SA LLIRERGA ATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG HVA +I Sbjct 1 MVISAVLLIRERGACATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGAHVAKII 60 Query 68 NEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFD 127 A L+LLD LID+YR+QL +TDFRAGCP+AAVSVEAG+ DRERMAPV+ AAAVFD Sbjct 61 GSATRSLDLLDTLIDQYREQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFD 120 Query 128 RWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLLLA 187 RWSDL AQRF++DGIP D AHELAV A STLEGA+LLARVRRDLTPL +VHRQLR++LLA Sbjct 121 RWSDLIAQRFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLYVVHRQLRSMLLA 180 Query 188 ELPERSR 194 +LPE +R Sbjct 181 QLPEGNR 187 >gi|342859348|ref|ZP_08716002.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342133589|gb|EGT86792.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=193 Score = 293 bits (750), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 149/180 (83%), Positives = 163/180 (91%), Gaps = 2/180 (1%) Query 8 MVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMI 67 MVVSAALLIRERGAHATAISDVL+HSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAA+I Sbjct 1 MVVSAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAVI 60 Query 68 NEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFD 127 A+ GL+LLD LIDKYR+QLL +DFRAGCPI AVSVEAG++ D ERM VI RAAAVFD Sbjct 61 AGADDGLQLLDTLIDKYRRQLLDSDFRAGCPIVAVSVEAGEQHDAERM--VIERAAAVFD 118 Query 128 RWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLLLA 187 RW+DL A RFIADGI P+RA ELAVLATS+LEGAI+LARVRRDL PLD+VHRQLR+LL A Sbjct 119 RWTDLIAARFIADGIAPERARELAVLATSSLEGAIVLARVRRDLMPLDVVHRQLRDLLAA 178 >gi|254819020|ref|ZP_05224021.1| putative transcriptional regulatory protein [Mycobacterium intracellulare ATCC 13950] Length=192 Score = 289 bits (740), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 146/180 (82%), Positives = 160/180 (89%), Gaps = 1/180 (0%) Query 8 MVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMI 67 MVVSAALLIRERGAHATAISDVL+HSGAPRGSAYHYFPGGRTQLLCEAVDYAG+HVAA+I Sbjct 1 MVVSAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLCEAVDYAGDHVAAII 60 Query 68 NEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFD 127 +A GL+L+D LIDK+RQQLL +DFRAGCPI AVSVEAG EQD ERMAPV+ RAAA FD Sbjct 61 ADAASGLDLIDTLIDKFRQQLLDSDFRAGCPIVAVSVEAG-EQDAERMAPVVERAAAAFD 119 Query 128 RWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLLLA 187 RW+DL AQRFIADGI +RA ELAVLA + LEGAILL RVRRDL PLD+V RQ+R LLLA Sbjct 120 RWTDLIAQRFIADGIARERAGELAVLAITALEGAILLVRVRRDLMPLDVVRRQVRELLLA 179 >gi|118463812|ref|YP_884106.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777424|ref|ZP_05218940.1| regulatory protein, TetR [Mycobacterium avium subsp. avium ATCC 25291] gi|118165099|gb|ABK65996.1| regulatory protein, TetR [Mycobacterium avium 104] Length=201 Score = 286 bits (732), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 146/189 (78%), Positives = 162/189 (86%), Gaps = 2/189 (1%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M+ PRE+MVVSAALLIRERGAHATAISDVL+HSGAPRGSAYHYFPGGRTQLLCEAVD+AG Sbjct 1 MRSPREKMVVSAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLCEAVDFAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 E+VAA+I AE G LLD LID YR+QL +DFRAGCP+ AV+VEAG++ D ER PVI Sbjct 61 EYVAAVIAGAESGARLLDTLIDTYREQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIE 118 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAA FDRW+DL AQRFIADGI RA ELAVLATS LEGAI+LAR RRD PLD+VHRQ Sbjct 119 RAAAAFDRWTDLIAQRFIADGIRRRRAAELAVLATSALEGAIVLARARRDPAPLDVVHRQ 178 Query 181 LRNLLLAEL 189 LR+LL AEL Sbjct 179 LRDLLAAEL 187 >gi|41409733|ref|NP_962569.1| hypothetical protein MAP3635 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398565|gb|AAS06185.1| hypothetical protein MAP_3635 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460059|gb|EGO38968.1| transcriptional regulator, tetR family [Mycobacterium avium subsp. paratuberculosis S397] Length=201 Score = 285 bits (730), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 145/189 (77%), Positives = 162/189 (86%), Gaps = 2/189 (1%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M+ PRE+MVVSAALLIRERGAHATAISDVL+HSGAPRGSAYHYFPGGRTQLLCEAVD+AG Sbjct 1 MRSPREKMVVSAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLCEAVDFAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 E+VAA+I AE G LLD LID YR+QL +DFRAGCP+ AV+VEAG++ D ER PVI Sbjct 61 EYVAAVIAGAESGSRLLDTLIDTYREQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIE 118 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAA FDRW+DL AQRF+ADGI RA ELAVLATS LEGAI+LAR RRD PLD+VHRQ Sbjct 119 RAAAAFDRWTDLIAQRFVADGIRRRRAAELAVLATSALEGAIVLARARRDPAPLDVVHRQ 178 Query 181 LRNLLLAEL 189 LR+LL AEL Sbjct 179 LRDLLAAEL 187 >gi|169628585|ref|YP_001702234.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169240552|emb|CAM61580.1| Putative TetR-family transcriptional regulator [Mycobacterium abscessus] Length=190 Score = 241 bits (616), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 117/185 (64%), Positives = 144/185 (78%), Gaps = 0/185 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMV SAALLIRERGAHATAISDVL+HSGAPRGSAYHYFPGGRTQLL EAVD AG Sbjct 1 MSTPRERMVASAALLIRERGAHATAISDVLEHSGAPRGSAYHYFPGGRTQLLSEAVDLAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 E++A MI+ ++ LD L+ YR+QL+ +DFRAGCP+ AV+VEAGD + +I Sbjct 61 EYIAGMIDAKPSAVDALDILVASYRKQLVRSDFRAGCPVVAVAVEAGDPESPASSQKLIE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 +AAVF RW DL A + +A G+ RA ELA+L T++LEGAI++AR RD+TP+D+VHRQ Sbjct 121 HSAAVFRRWIDLIADKLVAVGVVRTRADELAILMTTSLEGAIIIARSTRDITPIDVVHRQ 180 Query 181 LRNLL 185 LR L+ Sbjct 181 LRTLI 185 >gi|145223874|ref|YP_001134552.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145216360|gb|ABP45764.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=194 Score = 238 bits (608), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 122/194 (63%), Positives = 142/194 (74%), Gaps = 0/194 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMVVSAALLIRERGAH TAI+DVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYA Sbjct 1 MTTPRERMVVSAALLIRERGAHPTAIADVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAA 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 E +A ++ A L +LD L YR QL +DFRAGCP+ AV+VE+GD E+ APVI Sbjct 61 EFMAERLSRASSSLRVLDDLFGYYRTQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAA RWSD+ QR IADG+P A LA+L ++ EGAI++AR RDL PLDLV Q Sbjct 121 RAAAALTRWSDIIEQRLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQ 180 Query 181 LRNLLLAELPERSR 194 L +L+ A R + Sbjct 181 LASLIDARTVTRRK 194 >gi|315444203|ref|YP_004077082.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315262506|gb|ADT99247.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=194 Score = 238 bits (607), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 122/194 (63%), Positives = 142/194 (74%), Gaps = 0/194 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMVVSAALLIRERGAH TAI+DVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYA Sbjct 1 MTTPRERMVVSAALLIRERGAHPTAIADVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAA 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 E +A ++ A L +LD L YR QL +DFRAGCP+ AV+VE+GD E+ APVI Sbjct 61 EFMAERLSRASSSLRVLDDLFGYYRTQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAA RWSD+ QR IADG+P A LA+L ++ EGAI++AR RDL PLDLV Q Sbjct 121 RAAAALTRWSDIIEQRLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQ 180 Query 181 LRNLLLAELPERSR 194 L +L+ A R + Sbjct 181 LASLIDARTGTRRK 194 >gi|126435330|ref|YP_001071021.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|126235130|gb|ABN98530.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=194 Score = 236 bits (603), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 120/185 (65%), Positives = 139/185 (76%), Gaps = 0/185 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMV SAALLIRERGAH TAI+DVL HSGAPRGSAYH+FPGGRTQLLCEAVDYAG Sbjct 1 MATPRERMVRSAALLIRERGAHPTAIADVLAHSGAPRGSAYHHFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + VA I +A L LLD L YR+ L TD+RAGCP+ AV+VEAGD E+ PVIA Sbjct 61 DRVAEQIEQAPDSLTLLDGLFAGYRELLTRTDYRAGCPVVAVAVEAGDPDKPEQSEPVIA 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAA F RW+ L A R ADGI +RA ELA+L ++ EG I++AR RD+ PLD++HRQ Sbjct 121 RAATAFTRWTALIADRMTADGIDAERAAELAMLLLTSFEGGIVVARAARDVGPLDVIHRQ 180 Query 181 LRNLL 185 LR LL Sbjct 181 LRTLL 185 >gi|108799686|ref|YP_639883.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119868796|ref|YP_938748.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|108770105|gb|ABG08827.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119694885|gb|ABL91958.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] Length=194 Score = 236 bits (602), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 120/185 (65%), Positives = 139/185 (76%), Gaps = 0/185 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMV SAALLIRERGAH TAI+DVL HSGAPRGSAYH+FPGGRTQLLCEAVDYAG Sbjct 1 MATPRERMVRSAALLIRERGAHPTAIADVLAHSGAPRGSAYHHFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + VA I +A L LLD L YR+ L TD+RAGCP+ AV+VEAGD E+ PVIA Sbjct 61 DRVAEQIEQAPDSLALLDGLFAGYRELLTRTDYRAGCPVVAVAVEAGDPDKPEQSEPVIA 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAA F RW+ L A R ADGI +RA ELA+L ++ EG I++AR RD+ PLD++HRQ Sbjct 121 RAATAFTRWTALIADRMTADGIDAERAAELAMLLLTSFEGGIVVARAARDVGPLDVIHRQ 180 Query 181 LRNLL 185 LR LL Sbjct 181 LRTLL 185 >gi|118468501|ref|YP_887823.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118169788|gb|ABK70684.1| TetR-family protein transcriptional regulator [Mycobacterium smegmatis str. MC2 155] Length=195 Score = 232 bits (591), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 114/194 (59%), Positives = 141/194 (73%), Gaps = 0/194 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMV SAA+LIRERGAH TAI+DVL HSGAPRGSAYHYFPGGRTQLLCEA+DYA Sbjct 1 MASPRERMVRSAAVLIRERGAHPTAIADVLAHSGAPRGSAYHYFPGGRTQLLCEAIDYAS 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 +HV A ++ A LLD ++ ++R QLL++DFRAGCP+ AV+VEAGD + + V Sbjct 61 DHVTARLDRATDTFALLDDMVARFRDQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RA A F RW R DG+P +RA ELA L T+++EGA+L+AR RD+ PL+LVHRQ Sbjct 121 RAGAAFQRWIARITARLCDDGVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQ 180 Query 181 LRNLLLAELPERSR 194 LR L A ++ R Sbjct 181 LREQLTAATGKKDR 194 >gi|120403991|ref|YP_953820.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119956809|gb|ABM13814.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=199 Score = 226 bits (575), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 121/185 (66%), Positives = 139/185 (76%), Gaps = 0/185 (0%) Query 1 MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 M PRERMV+SAALLIRERGAH TAI+DVL HSGAPRGSAYHYFPGGRTQLLCEAVDYAG Sbjct 1 MTSPRERMVISAALLIRERGAHPTAIADVLAHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 Query 61 EHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 E +A + +A +E LD L D YR+QL +DFRAGCP+ AV+VEAGD E+ A VI Sbjct 61 EFIADRLAQASTTVEALDGLFDGYRKQLRDSDFRAGCPVVAVTVEAGDPDKPEQSAAVIE 120 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 RAAA F RW DL AQR IADG+ A LA+L ++ EGAI++AR RDL LDLV Q Sbjct 121 RAAAAFARWHDLLAQRLIADGLAQPAATALAMLVLTSFEGAIVVARASRDLAALDLVQEQ 180 Query 181 LRNLL 185 LR L+ Sbjct 181 LRELI 185 >gi|269127158|ref|YP_003300528.1| TetR family transcriptional regulator [Thermomonospora curvata DSM 43183] gi|268312116|gb|ACY98490.1| transcriptional regulator, TetR family [Thermomonospora curvata DSM 43183] Length=193 Score = 162 bits (411), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 98/192 (52%), Positives = 118/192 (62%), Gaps = 10/192 (5%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 RERMV SAA L RERG T DV+ HSGAPRGS YH+FPGG+ QL EAV YAGE + Sbjct 8 RERMVRSAAYLFRERGYSGTGFRDVIAHSGAPRGSIYHHFPGGKVQLAQEAVRYAGEFLN 67 Query 65 AMINEA-EGG--LELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIAR 121 A I +A EGG +DA + +R L+ + FRAGCP+AAV+VE DE P +A Sbjct 68 AGIEKAMEGGDPAAAVDAFVGWWRGVLIKSGFRAGCPVAAVTVECHDE------VPQLAE 121 Query 122 -AAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 AAAVFDRW D A GIP RA LA L + +EGA LL R RD+ PLD V + Sbjct 122 AAAAVFDRWQDTLATGLANAGIPDARAARLARLIVAAVEGATLLCRAHRDVRPLDDVVAE 181 Query 181 LRNLLLAELPER 192 L+ L A + +R Sbjct 182 LKELTRAAVRDR 193 >gi|117164804|emb|CAJ88353.1| putative TetR-family transcriptional regulator [Streptomyces ambofaciens ATCC 23877] Length=203 Score = 154 bits (388), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 86/192 (45%), Positives = 123/192 (65%), Gaps = 10/192 (5%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R+RM++SAA L+RE GA AT+I VL HSGAPRGS YH+FPGGR QL+ EAV AG+ +A Sbjct 9 RDRMILSAAALLREYGASATSIDRVLAHSGAPRGSVYHHFPGGRAQLIDEAVALAGDFIA 68 Query 65 AMIN---EAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIAR 121 +I+ +A+ +E +DA +R +L+ + FRAGCPI AV+VE D+ AP +AR Sbjct 69 GLIDAAVQADDPVEAVDAFFVLWRDRLVESGFRAGCPIVAVAVETNDD------APQLAR 122 Query 122 -AAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 AAAVF RW + A F+ G+ +R LA + +EGA+++ R + PL+ + Sbjct 123 SAAAVFARWQEALAALFLRHGLAEERGRRLAAFVIAAVEGAVIMCRAEQSTAPLEAAAAE 182 Query 181 LRNLLLAELPER 192 + +LLL L +R Sbjct 183 IHDLLLHALRDR 194 >gi|126432819|ref|YP_001068510.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|126232619|gb|ABN96019.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=205 Score = 149 bits (376), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 78/183 (43%), Positives = 114/183 (63%), Gaps = 7/183 (3%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R M++ AA ++RERGA I +VLQ SGAPRGS Y++FP GR+Q++ EA++YAGE + Sbjct 12 RTNMLIGAAEVLRERGAAGVTIDEVLQRSGAPRGSVYYHFPEGRSQIVAEALEYAGESIT 71 Query 65 AMINE--AEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 ++I+E A GG L++ +D + + L +DF AGCP+ A ++ G +D ++ V A Sbjct 72 SLIDEAAANGGRYLVEHFVDFWDRVLAESDFTAGCPVVAAAI--GSAEDGPQLTSV---A 126 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 A+F W + + F DG P A LA+ + + LEGA++L R RDL PL VH QL Sbjct 127 GAIFGHWREALTRAFEVDGCEPSEAASLAITSIAALEGAVVLCRATRDLDPLRQVHTQLE 186 Query 183 NLL 185 LL Sbjct 187 FLL 189 >gi|120401301|ref|YP_951130.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954119|gb|ABM11124.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=193 Score = 148 bits (373), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 83/184 (46%), Positives = 112/184 (61%), Gaps = 9/184 (4%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 RERM+ SA+ LIRE GA T++ D+L+HS APRGS YH+FPGGR QL+ E VD AG +A Sbjct 9 RERMLDSASTLIREHGASGTSLDDILRHSRAPRGSVYHHFPGGRAQLIEEVVDRAGGALA 68 Query 65 AMINEAEGGL--ELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 A++ +A D I ++ L ++ FRAGCP+ AV+VE D+ AP + A Sbjct 69 AILGDAGDATPATTFDVFISTWKAGLEASGFRAGCPVLAVAVETNDD------APQLTEA 122 Query 123 AA-VFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQL 181 AA F W D G+PP RA LA L + +EGA+ L+RV R+ P+D V R+L Sbjct 123 AARAFGSWRDALNTVLRHQGVPPARARRLATLIVAAVEGAVALSRVERNTQPIDDVAREL 182 Query 182 RNLL 185 R L+ Sbjct 183 RALI 186 >gi|302544751|ref|ZP_07297093.1| putative transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gi|302462369|gb|EFL25462.1| putative transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length=190 Score = 145 bits (367), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 84/189 (45%), Positives = 117/189 (62%), Gaps = 10/189 (5%) Query 8 MVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMI 67 MV SAA L+RE GA AT+I VL HSGAPRGS YH+FPGGRTQL+ EAV AG+ +A +I Sbjct 1 MVQSAAALLREYGASATSIDRVLAHSGAPRGSVYHHFPGGRTQLIDEAVALAGDVIAGLI 60 Query 68 N---EAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIAR-AA 123 + A+ + +DA +R +L+ + FRAGCPI AV+VE D+ AP +AR AA Sbjct 61 DAATRADDPVRAVDAFFALWRDRLVESGFRAGCPIVAVAVETNDD------APQLARSAA 114 Query 124 AVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRN 183 AVF RW + A+ + G+ +R L + +EGA+++ R R PL+ ++ + Sbjct 115 AVFARWREALAELLVRHGLTEERGRRLGAFIIAAVEGAVIMCRAERSTAPLEAAAVEIHD 174 Query 184 LLLAELPER 192 LLL L +R Sbjct 175 LLLNALHQR 183 >gi|297159014|gb|ADI08726.1| transcriptional regulator, TetR family protein [Streptomyces bingchenggensis BCW-1] Length=188 Score = 144 bits (364), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 81/182 (45%), Positives = 114/182 (63%), Gaps = 10/182 (5%) Query 8 MVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMI 67 MV+SAA L+RE GA AT+I VL HSGAPRGS YH+FPGGR QL+ EAV AG+ +A +I Sbjct 1 MVLSAAELLREYGAGATSIDRVLAHSGAPRGSVYHHFPGGRAQLIDEAVTLAGDFIAGLI 60 Query 68 N---EAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAA- 123 EA+G L ++D+ + +L+ + FRAGCPI AV+VE D+ AP +AR+A Sbjct 61 ETAAEADGPLAVVDSFFALWHDRLVESGFRAGCPIVAVAVETNDD------APHLARSAG 114 Query 124 AVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRN 183 AVF RW + A + G+P R LA + +EGA+++ R + PL+ ++ + Sbjct 115 AVFARWQEALAALLVRHGLPEARGRRLAAFIIAAVEGAVIMCRAEQSTAPLEAAAAEIHD 174 Query 184 LL 185 LL Sbjct 175 LL 176 >gi|300786219|ref|YP_003766510.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299795733|gb|ADJ46108.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] Length=198 Score = 141 bits (356), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 84/197 (43%), Positives = 112/197 (57%), Gaps = 11/197 (5%) Query 4 PRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHV 63 PRERMV+SAA L+R G AT + DV+ H+ APRGS HYFPGG+ QL+ EAV +AG++ Sbjct 5 PRERMVLSAAQLVRIHGVGATGMRDVVAHAEAPRGSLQHYFPGGKDQLIAEAVAWAGDYS 64 Query 64 AAMINEAEGGLE------LLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAP 117 A + LE L +A+ ++R + + F AGCP+ A + D R A Sbjct 65 ARRVARVAAKLEDPTPGKLFEAMAAQWRDEFTTAGFDAGCPLVATVADTAATSDELREA- 123 Query 118 VIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLV 177 + +A FD W A G+PP R+ LAVL S LEGAI+LAR RD+ PLD V Sbjct 124 -VGKA---FDGWQRPVAATLEQLGVPPARSTSLAVLMLSALEGAIVLARAHRDVAPLDTV 179 Query 178 HRQLRNLLLAELPERSR 194 +LR LL + +R R Sbjct 180 VAELRPLLDGAVDKRRR 196 >gi|325675978|ref|ZP_08155661.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] gi|325553216|gb|EGD22895.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] Length=207 Score = 141 bits (355), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 82/188 (44%), Positives = 114/188 (61%), Gaps = 11/188 (5%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 GPR M+ SA LIRE+G AT+ +DVL HSGAPRGS YH+FPGG++QL+ EA A + Sbjct 28 GPRAAMIDSAVALIREQGVAATSFADVLAHSGAPRGSIYHHFPGGKSQLVEEATRSAAAY 87 Query 63 VA---AMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVI 119 + A + E+ + L AL+D +R+ L +TD+ AGCPI A ++ G E+ +A V Sbjct 88 LGRGVARVLESGDTVSALRALVDLWRRGLEATDYEAGCPIVAAAL--GTERGAREVAGV- 144 Query 120 ARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHR 179 F W +L A + DG+P DR+ LAVL S LEGA+++A+ + PLD V Sbjct 145 -----TFAEWCELIAASLVEDGVPQDRSASLAVLVVSALEGALVMAQAQGTSAPLDAVVD 199 Query 180 QLRNLLLA 187 +L LL A Sbjct 200 ELEVLLRA 207 >gi|262200728|ref|YP_003271936.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262084075|gb|ACY20043.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=200 Score = 137 bits (346), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 79/186 (43%), Positives = 113/186 (61%), Gaps = 10/186 (5%) Query 2 QGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGE 61 +GPRERMV+ AA LI G AT+I DV+ S APRGS YH+FPGG+TQL+ EAV YAG+ Sbjct 16 RGPRERMVIHAADLIGRDGVAATSIGDVITASSAPRGSIYHHFPGGKTQLMTEAVRYAGD 75 Query 62 HVAAMINE--AEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVI 119 +A I + E + + D +R+ L++TD++ GCP+ A + G E P + Sbjct 76 FIADRIGTLRSHTAAEAVSDIGDVWRRMLVNTDYQFGCPVLAGGLARGTE-------PQV 128 Query 120 ARAA-AVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVH 178 A AA V +W ++ A R + +G+ DRA LA L +++EGA+ L + RR + PLD V Sbjct 129 ADAAEEVLTQWIEMVAARLVLEGVDADRAGSLANLVVASIEGAVGLCQTRRSVEPLDKVI 188 Query 179 RQLRNL 184 +L L Sbjct 189 VELAAL 194 >gi|134099489|ref|YP_001105150.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291008505|ref|ZP_06566478.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133912112|emb|CAM02225.1| TetR-family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] Length=191 Score = 136 bits (343), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 88/190 (47%), Positives = 116/190 (62%), Gaps = 6/190 (3%) Query 2 QGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGE 61 Q PR ++V AA +IR RG +AT+I +V +H+ AP GS YHYFPGG+ QL EAV +AGE Sbjct 6 QQPRLQLVAGAADMIRRRGLNATSIREVAKHAQAPLGSTYHYFPGGKRQLAGEAVRFAGE 65 Query 62 HVAAMI--NEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVI 119 V+ ++ N G +E L AL+D +R+ L TDF+AGCP+ AVSVE EQD E V Sbjct 66 TVSELLRKNLDAGPVEGLRALLDLWREILTGTDFQAGCPVLAVSVE---EQDDEGAE-VR 121 Query 120 ARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHR 179 A AA VF W L A G +RA +LA L S EGA+++ R +R LD V Sbjct 122 AAAAEVFGGWESLLADSLRQHGCDAERAPQLATLVVSAFEGAVVMCRAQRSTRALDHVGE 181 Query 180 QLRNLLLAEL 189 +L L+ AE+ Sbjct 182 RLEALIAAEV 191 >gi|329937018|ref|ZP_08286647.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329303625|gb|EGG47510.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=202 Score = 135 bits (339), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 79/199 (40%), Positives = 109/199 (55%), Gaps = 11/199 (5%) Query 2 QGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGE 61 +GPRERMV SAA LIR RG + DV+ H+ APRGS HYFPGG+ QL+ EAV +AG Sbjct 6 RGPRERMVFSAAQLIRRRGVAGAGMRDVVAHAHAPRGSLQHYFPGGKEQLVNEAVRWAGR 65 Query 62 HVAAMINEAEGGLE------LLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERM 115 + A + G+ LL A+ ++ Q+ F GCP+AA +V D + R Sbjct 66 YAARRVPRFMAGMTERTPAGLLAAMAGQWTQEYAREGFAGGCPVAAATVACADSVESTRE 125 Query 116 APVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLD 175 A AA F W+ + G+P RA LAV+ S +EGA+++AR RD+ L+ Sbjct 126 A-----AAGAFGEWTGAVRGALVEMGVPDARAEGLAVVMVSAVEGAVVVARAERDVRALE 180 Query 176 LVHRQLRNLLLAELPERSR 194 V R+L +L A + R R Sbjct 181 AVVRELGPVLDAAVERRDR 199 >gi|312140412|ref|YP_004007748.1| tetr family transcriptional regulator [Rhodococcus equi 103S] gi|311889751|emb|CBH49068.1| putative TetR family transcriptional regulator [Rhodococcus equi 103S] Length=175 Score = 134 bits (338), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 78/181 (44%), Positives = 110/181 (61%), Gaps = 11/181 (6%) Query 8 MVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA--- 64 M+ SA LIRE+G AT+ +DVL HSGAPRGS YH+FPGG++QL+ EA A ++ Sbjct 1 MIDSAVALIREQGVAATSFADVLAHSGAPRGSIYHHFPGGKSQLVEEATRSAAAYLGRGV 60 Query 65 AMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAA 124 A + E+ + L AL+D +R+ L +TD+ AGCPI A ++ G E+ +A V Sbjct 61 ARVLESGDTVSALRALVDLWRRGLEATDYEAGCPIVAAAL--GTERGAREVAGV------ 112 Query 125 VFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNL 184 F W +L A + DG+P DR+ LAVL S LEGA+++A+ + PLD V +L L Sbjct 113 TFAEWCELIAASLVEDGVPRDRSASLAVLVVSALEGALVMAQAQGTSAPLDAVVDELEVL 172 Query 185 L 185 L Sbjct 173 L 173 >gi|312197309|ref|YP_004017370.1| TetR family transcriptional regulator [Frankia sp. EuI1c] gi|311228645|gb|ADP81500.1| regulatory protein TetR [Frankia sp. EuI1c] Length=192 Score = 134 bits (337), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 79/187 (43%), Positives = 108/187 (58%), Gaps = 5/187 (2%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R+R+V AA +IR RG +AT+I +V +H+ P GS YHYFPGG+ QL+ EAV +AGE V Sbjct 7 RQRIVAGAADMIRRRGLNATSIREVAKHAQTPLGSTYHYFPGGKPQLVTEAVRFAGETVT 66 Query 65 AMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 + G ++ L A D +RQ L TDF+AGCP+ AVS+E + D R V+A A Sbjct 67 TTLRTMLRAGPVDGLGAFFDLWRQILTGTDFQAGCPVLAVSIE--EPADDARFT-VLAAA 123 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 A VF W D A+ G P A LA L + +EGA+ + R +R LD V Q+ Sbjct 124 ADVFGAWEDQLAESLRLHGADPADAESLATLVIAAIEGAVAMCRAQRSTRTLDRVATQVD 183 Query 183 NLLLAEL 189 L+ A + Sbjct 184 TLIRAAV 190 >gi|342859315|ref|ZP_08715969.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342133556|gb|EGT86759.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=213 Score = 134 bits (337), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 75/186 (41%), Positives = 110/186 (60%), Gaps = 6/186 (3%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R +M+ SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ Y+G+ + Sbjct 16 RTKMLASAADVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILTEALRYSGDSIT 75 Query 65 AMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 AMI++A G LL +D + + L F AGCP+ A ++ D+ D R++ A Sbjct 76 AMIDDAAGRGARVLLQEFVDFWERLLTDGGFTAGCPVVAAAIGCSDD-DGPRLS---TEA 131 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 A+ DRW ++ F+ DG A LAV++ + LEGA++L+R R+ PL V QL Sbjct 132 GAILDRWCTALSRAFVNDGFDDADAASLAVMSIAALEGAVVLSRSTRNAGPLHQVGEQLE 191 Query 183 NLLLAE 188 L+ A+ Sbjct 192 FLIKAK 197 >gi|343925713|ref|ZP_08765228.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343764064|dbj|GAA12154.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=201 Score = 133 bits (335), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/190 (43%), Positives = 111/190 (59%), Gaps = 18/190 (9%) Query 2 QGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGE 61 +GPRERM+V AA LI G AT+I DV+ S APRGS YH+FPGG+TQL+ EAV YAG+ Sbjct 16 RGPRERMIVHAADLIGRDGVAATSIGDVISASAAPRGSIYHHFPGGKTQLMTEAVQYAGD 75 Query 62 HVA------AMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERM 115 +A + AE E+ +R+ L++TDF+ GCP+ A + R Sbjct 76 FIAERLARRVTLTPAETVREIGGV----WRRMLVNTDFQFGCPVMAGGLA-------RRG 124 Query 116 APVIARAAA-VFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPL 174 P +A AAA + RW+DL R + DG+ +RA LA L + +EGA+ L + +R + PL Sbjct 125 EPEVADAAAEILRRWADLITARLVVDGVDSERADSLANLIVAAIEGAVALCQTQRSVEPL 184 Query 175 DLVHRQLRNL 184 D V +L L Sbjct 185 DRVIAELAAL 194 >gi|118616842|ref|YP_905174.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] gi|118568952|gb|ABL03703.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] Length=206 Score = 133 bits (334), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 75/187 (41%), Positives = 106/187 (57%), Gaps = 7/187 (3%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 G RE+M++SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ YAG+ Sbjct 13 GTREKMLISAAQVMRERGAAGVTIDSVLARSGAPRGSVYYHFPDGRNQILIEALRYAGDS 72 Query 63 VAAMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + A+I++A +G LL + + L F AGCP+ A ++ D++ + A Sbjct 73 ITAVIDKAADKGARALLREFVRLWEHLLTDGGFAAGCPVVAAALGPADDE-----VELAA 127 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A + D W + F+ADG A LAV + + LEGAI+L R R + PL V Q Sbjct 128 EAGTILDSWCAALGRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSVEPLRQVGEQ 187 Query 181 LRNLLLA 187 L L+ A Sbjct 188 LEFLVKA 194 >gi|291435352|ref|ZP_06574742.1| TetR-family protein transcriptional regulator [Streptomyces ghanaensis ATCC 14672] gi|291338247|gb|EFE65203.1| TetR-family protein transcriptional regulator [Streptomyces ghanaensis ATCC 14672] Length=198 Score = 132 bits (333), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 78/190 (42%), Positives = 106/190 (56%), Gaps = 11/190 (5%) Query 2 QGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGE 61 +GPRERMV SAA LIR G AT + +V H+ APRGS HYFPGG+ QL+ EAVD+AG Sbjct 4 RGPRERMVFSAAQLIRRDGVAATGMREVAAHARAPRGSLQHYFPGGKEQLVNEAVDWAGR 63 Query 62 HVAAMINEAEGGLE------LLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERM 115 + A ++ L L ++ ++ + + F GCP+AA +V+ R Sbjct 64 YAARRVDRFLAALAEPTPAGLFAQMVRQWTDEYEAAGFGGGCPVAAATVDRAGSAASTRE 123 Query 116 APVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLD 175 A A+A F W+ A+ G+P +RA LA L S+LEGAIL+AR RD+ L Sbjct 124 A-----ASAAFTHWTGAVARALSGMGVPEERAEPLATLMISSLEGAILMARAERDVRALT 178 Query 176 LVHRQLRNLL 185 V R+L LL Sbjct 179 AVSRELGPLL 188 >gi|240168440|ref|ZP_04747099.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=212 Score = 132 bits (332), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 75/185 (41%), Positives = 103/185 (56%), Gaps = 7/185 (3%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 G R++M+VSAA ++RERGA I VL SGAPRGS YH+FP GR Q+L EA+ YAG+ Sbjct 13 GTRDKMLVSAAQVLRERGAAGVTIDSVLARSGAPRGSVYHHFPDGRNQILSEALRYAGDS 72 Query 63 VAAMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + A+I A G LL +D ++ L DF AGCP+AA ++ + D+ + Sbjct 73 ITAVIENAADRGARVLLREFVDYWQHLLTEGDFTAGCPVAAAALGSADDG-----LELST 127 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A + + W + FI DG A LAV + + LEGAI+L R PL V Q Sbjct 128 EAGTILNGWCSALTRAFITDGFGESDAAALAVTSVAALEGAIMLCRSTHTAEPLRTVGDQ 187 Query 181 LRNLL 185 L+ L+ Sbjct 188 LQFLV 192 >gi|183980499|ref|YP_001848790.1| transcriptional regulatory protein [Mycobacterium marinum M] gi|183173825|gb|ACC38935.1| transcriptional regulatory protein [Mycobacterium marinum M] Length=206 Score = 132 bits (331), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 75/187 (41%), Positives = 105/187 (57%), Gaps = 7/187 (3%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 G RE+M++SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ YAG+ Sbjct 13 GTREKMLISAAQVMRERGAAGVTIDSVLARSGAPRGSVYYHFPDGRNQILIEALRYAGDS 72 Query 63 VAAMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + A+I++A +G LL + + L F AGCP+ A ++ D++ + A Sbjct 73 ITAVIDKAADKGARALLREFVRLWEHLLTDGGFAAGCPVVAAALGPADDE-----VELAA 127 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A + D W + F+ADG A LAV + + LEGAI+L R R PL V Q Sbjct 128 EAGTILDSWCAALGRAFVADGFDESTAASLAVTSIAALEGAIMLCRSTRSAEPLRQVGEQ 187 Query 181 LRNLLLA 187 L L+ A Sbjct 188 LEFLVKA 194 >gi|284047122|ref|YP_003397462.1| TetR family transcriptional regulator [Conexibacter woesei DSM 14684] gi|283951343|gb|ADB54087.1| transcriptional regulator, TetR family [Conexibacter woesei DSM 14684] Length=189 Score = 131 bits (330), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 80/188 (43%), Positives = 113/188 (61%), Gaps = 7/188 (3%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R+RMV SAALL+RERG T DV+ HS AP GS YH+FPGG+ QL EAV YAG+ V Sbjct 6 RDRMVRSAALLLRERGYAGTGFRDVIAHSEAPWGSIYHHFPGGKAQLAEEAVGYAGDVVT 65 Query 65 AMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 +I ++ + + L A + ++Q L ++ +RAGCP+ AV+ EA D+ + + A Sbjct 66 RLIEQSPPDDPVATLRAFVTIWKQGLETSGYRAGCPVLAVATEAPDD-----LPALTDAA 120 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 AA F RW + A G+P RA LA + + +EGA++L+R RRD PLD V ++L Sbjct 121 AAAFARWEEALAASLRRAGVPRARARRLATIVVAAIEGAVVLSRARRDTRPLDDVGKELE 180 Query 183 NLLLAELP 190 + LP Sbjct 181 LAIQDALP 188 >gi|296167451|ref|ZP_06849850.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897199|gb|EFG76806.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=219 Score = 130 bits (328), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 74/187 (40%), Positives = 109/187 (59%), Gaps = 7/187 (3%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 G R++M+ SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ Y+G+ Sbjct 27 GTRKKMLASAAEVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILIEALRYSGDA 86 Query 63 VAAMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + AMI++A +G LL ++ + ++L F AGCP+ A ++ + D+ A + A Sbjct 87 ITAMIDDAAEQGARVLLGKFVEFWERKLTEGGFNAGCPVVAAAIGSDDDD-----AKLSA 141 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A A+ RW + F DG A LAV++ + LEGAI+L+R + PL V Q Sbjct 142 EAGAILGRWCAALTRAFTHDGFDEPCAASLAVMSIAALEGAIVLSRSTGSIDPLRQVGDQ 201 Query 181 LRNLLLA 187 L L+ A Sbjct 202 LEFLIKA 208 >gi|118467192|ref|YP_884069.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777387|ref|ZP_05218903.1| transcriptional regulator, TetR family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118168479|gb|ABK69376.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] gi|336460033|gb|EGO38942.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=213 Score = 130 bits (328), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 72/187 (39%), Positives = 108/187 (58%), Gaps = 6/187 (3%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 G R +M+ SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ Y+G+ Sbjct 14 GTRTKMLASAAEVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILAEALRYSGDS 73 Query 63 VAAMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + A+I++A GG LL ++ + + L F AGCP+ A ++ +++ + + A Sbjct 74 ITALIDQAAGRGGRALLREFVEYWERLLTEGGFTAGCPVVAAAIGCSEDEGPK----LSA 129 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A A+ RW + F+ DG A LAV++ + LEG I+L+R R+ PL V Q Sbjct 130 EAGAILGRWCTALTRAFVNDGFDDADAASLAVMSIAALEGGIVLSRSTRNAGPLHQVGEQ 189 Query 181 LRNLLLA 187 L L+ A Sbjct 190 LEFLIKA 196 >gi|41409759|ref|NP_962595.1| hypothetical protein MAP3661c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398591|gb|AAS06211.1| hypothetical protein MAP_3661c [Mycobacterium avium subsp. paratuberculosis K-10] Length=261 Score = 130 bits (326), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 72/187 (39%), Positives = 108/187 (58%), Gaps = 6/187 (3%) Query 3 GPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEH 62 G R +M+ SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ Y+G+ Sbjct 62 GTRTKMLASAAEVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILAEALRYSGDS 121 Query 63 VAAMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIA 120 + A+I++A GG LL ++ + + L F AGCP+ A ++ +++ + + A Sbjct 122 ITALIDQAAGRGGRALLREFVEYWERLLTEGGFTAGCPVVAAAIGCSEDEGPK----LSA 177 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A A+ RW + F+ DG A LAV++ + LEG I+L+R R+ PL V Q Sbjct 178 EAGAILGRWCTALTRAFVNDGFDDADAASLAVMSIAALEGGIVLSRSTRNAGPLHQVGEQ 237 Query 181 LRNLLLA 187 L L+ A Sbjct 238 LEFLIKA 244 >gi|254822658|ref|ZP_05227659.1| transcriptional regulator, TetR family protein [Mycobacterium intracellulare ATCC 13950] Length=212 Score = 130 bits (326), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 74/186 (40%), Positives = 107/186 (58%), Gaps = 6/186 (3%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R +M+ SAA ++RERGA I VL SGAPRGS Y++FP GR Q+L EA+ Y+G+ + Sbjct 15 RTKMLASAAEVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILTEALRYSGDSIT 74 Query 65 AMINEA--EGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 A+I++A G ELL + + + L F AGCP+ A ++ D D +++ A Sbjct 75 ALIDDAAGRGARELLAEFVGYWERLLTEGGFTAGCPVVAAAIGCSD-GDGPKLS---TEA 130 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 A+ RW + F+ DG A LAV++ S LEGAI+L+R R+ PL V QL Sbjct 131 GAILGRWCTALTRAFVNDGFDDADAASLAVMSISALEGAIVLSRSTRNAGPLHQVGEQLE 190 Query 183 NLLLAE 188 L+ A+ Sbjct 191 FLIKAK 196 >gi|297196674|ref|ZP_06914072.1| TetR family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] gi|297153334|gb|EFH32303.1| TetR family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] Length=196 Score = 128 bits (322), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 76/183 (42%), Positives = 107/183 (59%), Gaps = 5/183 (2%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 RER+V AA +I RG AT+I ++ +H+ AP GS YHYFP G+ QL EAV + GE VA Sbjct 11 RERIVAGAADMISRRGLSATSIREMAKHAEAPLGSTYHYFPEGKQQLAAEAVRHTGEWVA 70 Query 65 -AMINEAEGGLEL-LDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 A+ E E G L A + +R+ ++ TDF AGCP+ AV++E E + + P +A A Sbjct 71 RALRKELEAGPAAGLRAFLALWRKIVVDTDFHAGCPVLAVAIE---EPPADEVPPALAAA 127 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 A VFDRW L A G ++A ++A L + +EG + L R +R PLD QL+ Sbjct 128 AEVFDRWEGLLADSLREHGADAEQAAQVATLIVAAVEGTVALCRAKRSTEPLDRTAAQLQ 187 Query 183 NLL 185 L+ Sbjct 188 ALI 190 >gi|239820822|ref|YP_002948007.1| transcriptional regulator, TetR family [Variovorax paradoxus S110] gi|239805675|gb|ACS22741.1| transcriptional regulator, TetR family [Variovorax paradoxus S110] Length=196 Score = 126 bits (317), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 72/187 (39%), Positives = 106/187 (57%), Gaps = 4/187 (2%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R++M+ AA L+ RG HAT++ V+QH+G PRGS H+FPGG+ QLL EAV +A E VA Sbjct 6 RDKMIAGAADLLSRRGVHATSLRTVVQHTGTPRGSLGHHFPGGKQQLLEEAVRHAAESVA 65 Query 65 A---MINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVE-AGDEQDRERMAPVIA 120 + + G +E L A + +R+ L S+ F AGCP+ AV+VE DE+D + Sbjct 66 VPLETLMKERGAVEGLQAFVGWWRRILESSGFEAGCPVLAVAVEPMADEEDAASGEHLRE 125 Query 121 RAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQ 180 A F+RW + A +G+ RA L L + +EG + + R R LD V + Sbjct 126 LAREAFERWEAILAAALRREGVAAGRAQRLGALTVAAIEGTVAMCRASRSTRALDDVQLE 185 Query 181 LRNLLLA 187 L+ +L+A Sbjct 186 LKAMLMA 192 >gi|258651043|ref|YP_003200199.1| TetR family transcriptional regulator [Nakamurella multipartita DSM 44233] gi|258554268|gb|ACV77210.1| transcriptional regulator, TetR family [Nakamurella multipartita DSM 44233] Length=194 Score = 126 bits (317), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 74/187 (40%), Positives = 111/187 (60%), Gaps = 10/187 (5%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R RMV AA +I RG A ++ ++ + G P GS YH+FPGG+ L+ EAV+Y G+ VA Sbjct 6 RARMVTGAARMISRRGVDAMSLRELAEQEGVPLGSTYHFFPGGKAALVDEAVNYVGDQVA 65 Query 65 AMI--NEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 I + +G ++ ++ +R+ LL +DF+AGCP+ A +V A DE+ R A A Sbjct 66 GSIAATQGKGTEHIVRWVLFAWRRILLRSDFQAGCPVLAAAV-AKDERHR-------ATA 117 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 AVFDRW+ + + DG+P DRA +A ++LEGA+ LAR ++ PLD V +L Sbjct 118 RAVFDRWTTGLIEVLVDDGVPADRAPAVARTVIASLEGAVGLARAFGEIGPLDDVQGELI 177 Query 183 NLLLAEL 189 L+ A + Sbjct 178 ALVRAAV 184 >gi|318057765|ref|ZP_07976488.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actG] gi|318081625|ref|ZP_07988939.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actF] Length=196 Score = 125 bits (315), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 80/195 (42%), Positives = 110/195 (57%), Gaps = 12/195 (6%) Query 4 PRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHV 63 PRER+V SAA L+R G T + + + +GAPRGS HYFPGG+ QL+ EAVD+AG + Sbjct 6 PRERVVFSAAQLLRRGGVAGTGMREAVTRAGAPRGSLQHYFPGGKEQLVNEAVDWAGRYA 65 Query 64 AAMINEAEGGLE------LLDALIDKYRQQLLS-TDFRAGCPIAAVSVEAGDEQDRERMA 116 A ++ L+ L A++ ++ ++ F AGCP+AA +V++ D +A Sbjct 66 ARRVDRFVAALDTPSPSGLFAAMVGQWTEEYEGEAGFAAGCPVAAATVDSADA-----VA 120 Query 117 PVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDL 176 AA FD W A A G+P R H LA L S+LEGA+LLAR D+ PL Sbjct 121 STRTAAARAFDGWLTAVAGALRAMGVPEARTHALATLMISSLEGALLLARATCDVRPLHD 180 Query 177 VHRQLRNLLLAELPE 191 V R+L LL A +PE Sbjct 181 VVRELGPLLDAAVPE 195 >gi|302555869|ref|ZP_07308211.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302473487|gb|EFL36580.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=202 Score = 125 bits (314), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 82/194 (43%), Positives = 110/194 (57%), Gaps = 19/194 (9%) Query 2 QGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGE 61 +GPRERMV SAA LIR G AT + +V H+GAPRGS HYFPGG+ QL+ EAV +AG Sbjct 10 RGPRERMVFSAAQLIRRDGVAATGMREVAAHAGAPRGSLQHYFPGGKEQLVNEAVGWAGR 69 Query 62 H--------VAAMINEAEGGL--ELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQD 111 + +AA+ GL E++ D+YR + F GCP+AA +V+ + Sbjct 70 YAAGRVARFLAALAEPTPSGLFAEMVRQWTDEYR----TAGFAGGCPVAAATVDCAESTP 125 Query 112 RERMAPVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDL 171 R A AAA F W++ + G+P +R+ LA L S+LEGAIL+AR RD+ Sbjct 126 ATREA-----AAAAFAAWTEPVGRALTEMGVPEERSGALATLMISSLEGAILIARAERDV 180 Query 172 TPLDLVHRQLRNLL 185 L V R+L LL Sbjct 181 RALTAVTRELGPLL 194 >gi|333919608|ref|YP_004493189.1| TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333481829|gb|AEF40389.1| Transcriptional regulator, TetR family [Amycolicicoccus subflavus DQS3-9A1] Length=197 Score = 125 bits (314), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 69/183 (38%), Positives = 112/183 (62%), Gaps = 7/183 (3%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 R+RMV SA L+RERG+ I +L S APRGS Y++FP GR Q++ EA++ + + ++ Sbjct 12 RDRMVFSAIELMRERGSAGVTIDAILTRSEAPRGSVYYHFPAGRNQIIAEALEGSSKAIS 71 Query 65 AMINE--AEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 A+I A+G +E L + + Q L ++D++AGCP+ V+V AG +D ++ A ++A Sbjct 72 ALIESAIADGPIEGLRRIRAFWAQILQASDYQAGCPV--VAVIAGGGEDEQQHAQIVAD- 128 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 F W + + +A+G+ RA LA + S++EGA+++ R R LTPLD V +L Sbjct 129 --TFQVWQEALLEALVAEGVARVRAQSLATMIISSIEGAVIVCRAERGLTPLDSVIAELE 186 Query 183 NLL 185 L+ Sbjct 187 QLI 189 >gi|29833709|ref|NP_828343.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29610833|dbj|BAC74878.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=196 Score = 125 bits (313), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 81/187 (44%), Positives = 113/187 (61%), Gaps = 5/187 (2%) Query 5 RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA 64 RER+V AA LI RG +AT+I ++ +H+ AP GS YH+FP G+ QL EAV YAGE VA Sbjct 9 RERIVAGAADLISRRGLNATSIRELAKHAKAPLGSTYHFFPEGKQQLATEAVRYAGEAVA 68 Query 65 AMINE--AEGGLELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARA 122 ++ + A G + L A + +R ++ +DFRAGCP+ AVSVE E + + P + A Sbjct 69 RILRKELAAGPVAGLRAFLALWRGIVVESDFRAGCPVLAVSVE---EPPADEIPPALVAA 125 Query 123 AAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLR 182 A F+ W L AQ A G D+A LA L +++EGAI + R +R PLD V +QL Sbjct 126 AEAFEEWEHLLAQALRAHGADSDQAPGLAALIVASVEGAIAMCRAKRSTDPLDQVAQQLE 185 Query 183 NLLLAEL 189 L++ L Sbjct 186 VLIVGAL 192 >gi|302540382|ref|ZP_07292724.1| putative transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gi|302458000|gb|EFL21093.1| putative transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length=196 Score = 124 bits (310), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 79/187 (43%), Positives = 111/187 (60%), Gaps = 7/187 (3%) Query 3 GP--RERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG 60 GP R+R+V AA +I RG +AT+I ++ +H+ AP GS YHYFP G+ QL EAV YAG Sbjct 7 GPQARQRIVAGAADMISRRGLNATSIREMAKHAEAPLGSTYHYFPEGKQQLATEAVRYAG 66 Query 61 EHVAAMI-NEAEGG-LELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPV 118 E +A M+ E E G + L A + +R ++ T+FRAGCP+ AVS+E + P Sbjct 67 ETIARMLRKELEAGPVAGLRAFLGLWRTIVIDTEFRAGCPVLAVSIEE---PPPGEIPPA 123 Query 119 IARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVH 178 +A AAAVFD W L A G P +A +LA L + +EG + + R +R + PLD Sbjct 124 LAAAAAVFDDWEKLLANSLREHGAAPGQAEQLATLTVAAVEGTVAMCRAKRSIEPLDRTA 183 Query 179 RQLRNLL 185 QL+ L+ Sbjct 184 EQLQALI 190 Lambda K H 0.322 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 198992683544 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40