BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0206c Length=944 Score E Sequences producing significant alignments: (Bits) Value gi|15607347|ref|NP_214720.1| transmembrane transport protein Mmp... 1891 0.0 gi|340625243|ref|YP_004743695.1| putative transmembrane transpor... 1889 0.0 gi|15839586|ref|NP_334623.1| MmpL family membrane protein [Mycob... 1887 0.0 gi|254549145|ref|ZP_05139592.1| transmembrane transport protein ... 1887 0.0 gi|31791384|ref|NP_853877.1| transmembrane transport protein Mmp... 1887 0.0 gi|289572786|ref|ZP_06453013.1| transmembrane transporter mmpL3 ... 1886 0.0 gi|148821399|ref|YP_001286153.1| transmembrane transport protein... 1885 0.0 gi|339293270|gb|AEJ45381.1| transmembrane transport protein mmpL... 1873 0.0 gi|289756271|ref|ZP_06515649.1| transmembrane transporter mmpL3 ... 1616 0.0 gi|289748682|ref|ZP_06508060.1| transmembrane transporter mmpL3 ... 1612 0.0 gi|289764322|ref|ZP_06523700.1| conserved hypothetical protein [... 1459 0.0 gi|15828415|ref|NP_302678.1| integral membrane protein [Mycobact... 1424 0.0 gi|183980477|ref|YP_001848768.1| transmembrane transport protein... 1371 0.0 gi|118616824|ref|YP_905156.1| transmembrane transport protein Mm... 1368 0.0 gi|240168410|ref|ZP_04747069.1| transmembrane transport protein ... 1355 0.0 gi|41409739|ref|NP_962575.1| MmpL3 [Mycobacterium avium subsp. p... 1277 0.0 gi|289760309|ref|ZP_06519687.1| transmembrane transporter mmpL3 ... 1277 0.0 gi|342859338|ref|ZP_08715992.1| MmpL3 [Mycobacterium colombiense... 1254 0.0 gi|118464977|ref|YP_884089.1| MmpL3 protein [Mycobacterium avium... 1246 0.0 gi|120401223|ref|YP_951052.1| large membrane protein [Mycobacter... 1189 0.0 gi|296167426|ref|ZP_06849826.1| transmembrane transport protein ... 1176 0.0 gi|333988809|ref|YP_004521423.1| transporter [Mycobacterium sp. ... 1150 0.0 gi|254822115|ref|ZP_05227116.1| MmpL3 protein [Mycobacterium int... 1126 0.0 gi|254777407|ref|ZP_05218923.1| MmpL3 protein [Mycobacterium avi... 1115 0.0 gi|169631582|ref|YP_001705231.1| putative membrane protein MmpL ... 1038 0.0 gi|111022141|ref|YP_705113.1| hypothetical protein RHA1_ro05174 ... 793 0.0 gi|312141446|ref|YP_004008782.1| integral membrane protein mmpl5... 787 0.0 gi|226364634|ref|YP_002782416.1| hypothetical protein ROP_52240 ... 782 0.0 gi|325677137|ref|ZP_08156805.1| membrane protein MmpL [Rhodococc... 773 0.0 gi|226304573|ref|YP_002764531.1| hypothetical protein RER_10840 ... 772 0.0 gi|229494459|ref|ZP_04388222.1| putative membrane protein [Rhodo... 771 0.0 gi|119854939|ref|YP_935544.1| MmpL family membrane protein [Myco... 744 0.0 gi|262204299|ref|YP_003275507.1| drug exporter of the RND superf... 740 0.0 gi|326383554|ref|ZP_08205240.1| drug exporter of the RND superfa... 727 0.0 gi|54027460|ref|YP_121702.1| hypothetical protein nfa54860 [Noca... 723 0.0 gi|343924436|ref|ZP_08763985.1| hypothetical protein GOALK_016_0... 707 0.0 gi|333921790|ref|YP_004495371.1| hypothetical protein AS9A_4137 ... 699 0.0 gi|317509188|ref|ZP_07966812.1| hypothetical protein HMPREF9336_... 676 0.0 gi|296395212|ref|YP_003660096.1| MMPL domain-containing protein ... 639 0.0 gi|319949688|ref|ZP_08023721.1| integral membrane protein MmpL5 ... 631 2e-178 gi|145221060|ref|YP_001131738.1| RND superfamily drug efflux pro... 617 3e-174 gi|108797151|ref|YP_637348.1| RND superfamily drug efflux protei... 617 4e-174 gi|126432773|ref|YP_001068464.1| RND superfamily drug efflux pro... 616 7e-174 gi|296138103|ref|YP_003645346.1| large membrane protein [Tsukamu... 611 2e-172 gi|334697758|gb|AEG82555.1| drug exporter of the RND superfamily... 600 3e-169 gi|68535213|ref|YP_249918.1| RND superfamily drug exporter [Cory... 598 1e-168 gi|300859365|ref|YP_003784348.1| RND superfamily drug exporter [... 598 1e-168 gi|337291783|ref|YP_004630804.1| RND superfamily drug exporter [... 598 2e-168 gi|260578589|ref|ZP_05846499.1| drug exporter of the RND family ... 597 4e-168 gi|336325108|ref|YP_004605074.1| RND superfamily membrane protei... 596 8e-168 >gi|15607347|ref|NP_214720.1| transmembrane transport protein MmpL3 [Mycobacterium tuberculosis H37Rv] gi|148659970|ref|YP_001281493.1| putative transmembrane transport protein MmpL3 [Mycobacterium tuberculosis H37Ra] gi|167968796|ref|ZP_02551073.1| transmembrane transport protein mmpL3 [Mycobacterium tuberculosis H37Ra] 49 more sequence titles Length=944 Score = 1891 bits (4898), Expect = 0.0, Method: Compositional matrix adjust. Identities = 943/944 (99%), Positives = 944/944 (100%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|340625243|ref|YP_004743695.1| putative transmembrane transport protein MMPL3 [Mycobacterium canettii CIPT 140010059] gi|340003433|emb|CCC42553.1| putative conserved transmembrane transport protein MMPL3 [Mycobacterium canettii CIPT 140010059] Length=944 Score = 1889 bits (4894), Expect = 0.0, Method: Compositional matrix adjust. Identities = 942/944 (99%), Positives = 944/944 (100%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRF+VIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFMVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|15839586|ref|NP_334623.1| MmpL family membrane protein [Mycobacterium tuberculosis CDC1551] gi|13879701|gb|AAK44437.1| membrane protein, MmpL family [Mycobacterium tuberculosis CDC1551] Length=944 Score = 1887 bits (4889), Expect = 0.0, Method: Compositional matrix adjust. Identities = 941/944 (99%), Positives = 942/944 (99%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDER PVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERNXPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|254549145|ref|ZP_05139592.1| transmembrane transport protein mmpL3 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=944 Score = 1887 bits (4888), Expect = 0.0, Method: Compositional matrix adjust. Identities = 942/944 (99%), Positives = 943/944 (99%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYR RFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRDRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|31791384|ref|NP_853877.1| transmembrane transport protein MmpL3 [Mycobacterium bovis AF2122/97] gi|121636118|ref|YP_976341.1| transmembrane transport protein mmpL3 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988591|ref|YP_002643278.1| conserved transmembrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] 6 more sequence titles Length=944 Score = 1887 bits (4887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 941/944 (99%), Positives = 943/944 (99%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAG WGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGIWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVT+AQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTEAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|289572786|ref|ZP_06453013.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis K85] gi|289537217|gb|EFD41795.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis K85] Length=944 Score = 1886 bits (4886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 940/944 (99%), Positives = 943/944 (99%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKH+TQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHITQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAG WGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGIWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVT+AQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTEAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|148821399|ref|YP_001286153.1| transmembrane transport protein mmpL3 [Mycobacterium tuberculosis F11] gi|148719926|gb|ABR04551.1| transmembrane transport protein mmpL3 [Mycobacterium tuberculosis F11] Length=944 Score = 1885 bits (4882), Expect = 0.0, Method: Compositional matrix adjust. Identities = 941/944 (99%), Positives = 942/944 (99%), Gaps = 0/944 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSS ASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSRASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 TRLAAAGRSVQSPASTPPPTPTPPSA SAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR Sbjct 841 TRLAAAGRSVQSPASTPPPTPTPPSALSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR 900 Query 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 >gi|339293270|gb|AEJ45381.1| transmembrane transport protein mmpL3 [Mycobacterium tuberculosis CCDC5079] gi|339296916|gb|AEJ49026.1| transmembrane transport protein mmpL3 [Mycobacterium tuberculosis CCDC5180] Length=936 Score = 1873 bits (4851), Expect = 0.0, Method: Compositional matrix adjust. Identities = 935/936 (99%), Positives = 936/936 (100%), Gaps = 0/936 (0%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 +YRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH Sbjct 1 MYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 60 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYT 128 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYT Sbjct 61 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYT 120 Query 129 FVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRRMEVLA 188 FVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRRMEVLA Sbjct 121 FVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRRMEVLA 180 Query 189 LPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGI 248 LPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGI Sbjct 181 LPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGI 240 Query 249 AIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLK 308 AIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLK Sbjct 241 AIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLK 300 Query 309 SLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLA 368 SLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLA Sbjct 301 SLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLA 360 Query 369 DRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLP 428 DRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLP Sbjct 361 DRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLP 420 Query 429 PTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDND 488 PTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDND Sbjct 421 PTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDND 480 Query 489 PANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALE 548 PANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALE Sbjct 481 PANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALE 540 Query 549 LDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVD 608 LDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVD Sbjct 541 LDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVD 600 Query 609 GHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTA 668 GHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTA Sbjct 601 GHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTA 660 Query 669 ATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGD 728 ATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGD Sbjct 661 ATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGD 720 Query 729 DCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDP 788 DCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDP Sbjct 721 DCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDP 780 Query 789 THPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGR 848 THPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGR Sbjct 781 THPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGR 840 Query 849 SVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEA 908 SVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEA Sbjct 841 SVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEA 900 Query 909 ATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 ATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL Sbjct 901 ATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 936 >gi|289756271|ref|ZP_06515649.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis EAS054] gi|289696858|gb|EFD64287.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis EAS054] Length=889 Score = 1616 bits (4184), Expect = 0.0, Method: Compositional matrix adjust. Identities = 854/869 (99%), Positives = 857/869 (99%), Gaps = 3/869 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT 840 Query 841 TRLAAAGRSVQSPASTPPPTP--TPPSAP 867 TRLAA RSV++ AS T TPP P Sbjct 841 TRLAAC-RSVRAVASIHAATKPRTPPFGP 868 >gi|289748682|ref|ZP_06508060.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis T92] gi|289689269|gb|EFD56698.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis T92] Length=914 Score = 1612 bits (4175), Expect = 0.0, Method: Compositional matrix adjust. Identities = 852/902 (95%), Positives = 856/902 (95%), Gaps = 18/902 (1%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG 780 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAP-AAPSGASTTRMQIGSSTEP- 838 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAP A G T + G EP Sbjct 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPGGAVWGEHHTGCRSGRRREPP 840 Query 839 --PTTRLAAAGRSV---QSPASTPPPTPTPPSAPSAGQTRAMP----LAANRSTDAAGDP 889 P +RL AGRSV Q P PP P P P R+ P L STDAAGDP Sbjct 841 DYPASRL--AGRSVAVRQHPRR--PPNPDPAIGPVC---RSDPGYVSLRRTASTDAAGDP 893 Query 890 AE 891 AE Sbjct 894 AE 895 >gi|289764322|ref|ZP_06523700.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] gi|289711828|gb|EFD75844.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] Length=776 Score = 1459 bits (3776), Expect = 0.0, Method: Compositional matrix adjust. Identities = 757/769 (99%), Positives = 759/769 (99%), Gaps = 3/769 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP Sbjct 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPV--SNGRPARP 767 SVMKLLGDDCWWAPRWARRLQTRIGLG P R + V SNGRPARP Sbjct 721 SVMKLLGDDCWWAPRWARRLQTRIGLGR-DPPARRAQVVLSSNGRPARP 768 >gi|15828415|ref|NP_302678.1| integral membrane protein [Mycobacterium leprae TN] gi|221230892|ref|YP_002504308.1| hypothetical protein MLBr_02620 [Mycobacterium leprae Br4923] gi|6225685|sp|O06081.1|MMPL3_MYCLE RecName: Full=Putative membrane protein mmpL3 gi|2104606|emb|CAB08813.1| unknown [Mycobacterium leprae] gi|13093845|emb|CAC32152.1| conserved integral membrane protein [Mycobacterium leprae] gi|219933999|emb|CAR72720.1| conserved integral membrane protein [Mycobacterium leprae Br4923] Length=955 Score = 1424 bits (3685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/966 (76%), Positives = 817/966 (85%), Gaps = 33/966 (3%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIG+ VALCL GGVFGLSLGKHVTQSGFYDD SQSV+AS+LGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQSVKASILGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-- 118 YGRDRSGHIVAIF AP GKTV+DPAW+KK+ DELN+FQ+++ ++V GWAGYLRAS T Sbjct 61 YGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQRNNSNKVTGWAGYLRASDTTNT 120 Query 119 ---GMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 GMAT DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ+LDGGTV+LAGL P+A ALT Sbjct 121 VVQGMATPDKKYTFVSIPLKGDDDDTILNNYKAIAPDLQKLDGGTVQLAGLDPIANALTS 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TIATDQRRMEVLALPLVAVVLF VFGGVIAA LPVMVGGL IAGALGI+RF+A+FGPVH+ Sbjct 181 TIATDQRRMEVLALPLVAVVLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVVSLIGLGIA+DYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTVTFSAVLI AS Sbjct 241 FAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 LLL PQGF+KSLTYA IA+V L+A+LSIT+LPACL IL KHVDALGVRTLFRVP L Sbjct 301 GASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALGVRTLFRVPLLR 360 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 NW++S A LNWLADRLQ+TKTREEVEAGFWGKLVN VMKRP++FA PIVI MILL+IP+G Sbjct 361 NWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMKRPLVFAIPIVIGMILLVIPLG 420 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 LS GG+SEKYLPP N+VRQ+QE FD+LFPGYRTNPLTLVIQTSNHQPVTD +IADIRSK Sbjct 421 NLSFGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIQTSNHQPVTDQEIADIRSK 480 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 AMAI GFIEPDN+ NMWQER A GASKDPSVRVLQNGLINP DASKK+ ELR+ITPPK Sbjct 481 AMAISGFIEPDNNYVNMWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPK 540 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 G+TV VGGTPALE DSIH L A+ PLMV++L+TTT++LMFLAFGS VLPIKA +MSALTL Sbjct 541 GLTVSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVMSALTL 600 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 GSTMGILTWIFVDGH SKWLNFTPTPL +I L++A+ +GL+TDYEVFLVSRMVEAR Sbjct 601 GSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATDYEVFLVSRMVEARAE 660 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 MSTQEA+RIGTA+TGR+ITAAAL++AVVAG+FVFSDLVMMKYLAFGLMAALLLDATVVR Sbjct 661 SMSTQEAVRIGTASTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVR 720 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVA 775 MFLVPSVMKLLGDDCWWAPRWAR LQ RIGLGEIHLPDER+RP +GRP RPPVTA +A Sbjct 721 MFLVPSVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVTAASLA 780 Query 776 ARAAGDPRPPHDPTHPLAESP-RPARSSPASSPELTPALEATAAPAAPSGASTTRMQI-- 832 A A+ R P PTHP P + ARS AS P++ E PSGAST R+Q+ Sbjct 781 APAS---RVPRGPTHPATLEPSQRARSGLASRPQIKRPQE------LPSGASTARIQMRP 831 Query 833 GSSTEPPTTRLAAAGRS-----------VQSP--ASTPPPTPTPPSAPSAGQTRAMPLAA 879 S E TTRL+ G + VQ+ A+T P PTP +P++GQTRAMP+ A Sbjct 832 SQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTP--SPASGQTRAMPVPA 889 Query 880 NRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQRRRG-GGALSAQDLL 938 NRS+D A + AEPT ALPI+R +DSE ATE+LNA G D +RQ RR GG +SAQDLL Sbjct 890 NRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNALGQGDNSRQHRRATGGGISAQDLL 949 Query 939 RREGRL 944 RREGRL Sbjct 950 RREGRL 955 >gi|183980477|ref|YP_001848768.1| transmembrane transport protein MmpL3 [Mycobacterium marinum M] gi|183173803|gb|ACC38913.1| conserved transmembrane transport protein MmpL3 [Mycobacterium marinum M] Length=960 Score = 1371 bits (3548), Expect = 0.0, Method: Compositional matrix adjust. Identities = 726/975 (75%), Positives = 813/975 (84%), Gaps = 46/975 (4%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGV VALCLGGGVFGLSLGKHVTQSGFYD+GSQSV AS+LGD+V Sbjct 1 MFAWWGRTVYRYRFIVIGVTVALCLGGGVFGLSLGKHVTQSGFYDEGSQSVTASILGDEV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-- 118 YGRDR+GHIVA+F+AP GKTV+DPAWSKK+ D+LN+F +DHPDQVLGWAGYLRA +T Sbjct 61 YGRDRTGHIVAVFKAPDGKTVNDPAWSKKITDQLNQFVKDHPDQVLGWAGYLRAPDSTSP 120 Query 119 ---GMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 GMAT DKKYTFVSIPLKGDDDDTILNNYK IAP LQ+LDGGTV+LAGL+PVAE LTG Sbjct 121 VIKGMATDDKKYTFVSIPLKGDDDDTILNNYKDIAPSLQKLDGGTVQLAGLEPVAEGLTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TIATDQRRMEVLALPLVAVVLF VFGG +AA LPVMVGGL IAGALGI+R +A+FGPVH+ Sbjct 181 TIATDQRRMEVLALPLVAVVLFLVFGGAVAACLPVMVGGLSIAGALGILRLVAVFGPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVVSLIGLGIA+DYGLF+VSRFREEIAEGYDTETAVRRTV+TAGRTV FSAVLI+AS Sbjct 241 FAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTETAVRRTVMTAGRTVAFSAVLIMAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 LL+ PQGF+KSLTYA +A+V L+A+LSIT+LPACLG+LG+HVDALGVRT FRVPFL Sbjct 301 GASLLMLPQGFVKSLTYALLAAVGLAALLSITLLPACLGVLGRHVDALGVRTAFRVPFLR 360 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 NWK+S AYLNWLADRLQ+TKTREEVEAGFWG L NRVM+RP++FA PIV+ MILL+IP+ Sbjct 361 NWKVSRAYLNWLADRLQKTKTREEVEAGFWGNLTNRVMRRPLVFAIPIVLGMILLVIPLF 420 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 LSLGG+SEKYLPP N+VRQ+QE FD+LFPGYRTNPLTLVI+++N+QPVTD QIADIRSK Sbjct 421 NLSLGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIKSTNNQPVTDQQIADIRSK 480 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 AM+I GFI+ DND +MWQER+YA G SKDPSVRVLQNGLINP DA KL ELRAITPPK Sbjct 481 AMSISGFIDQDNDADSMWQERSYAPGGSKDPSVRVLQNGLINPGDAPTKLAELRAITPPK 540 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 G+ + VGGTPALE DSIH LF MP M+VILLTTT +LMFLAFGSVVLPIKA +MSALTL Sbjct 541 GLEIFVGGTPALEQDSIHSLFENMPAMLVILLTTTTLLMFLAFGSVVLPIKAAVMSALTL 600 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 GSTMGILTWIFVDGH S LNFT TPLTAPVI L++A+ +GL+TDYEVFLVSRMVEARE Sbjct 601 GSTMGILTWIFVDGHGSGVLNFTATPLTAPVIALVVAVGYGLATDYEVFLVSRMVEAREN 660 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 GMSTQEAIRIGTA TGR+ITAAAL++AVVAG+FVFSDLVMMKYLAFGLMAALLLDATVVR Sbjct 661 GMSTQEAIRIGTATTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVR 720 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVA 775 MFLVPSVMKLLGDDCWWAPRW RRLQTRIGLGEI LPDERKRP +NG ARPPV A L A Sbjct 721 MFLVPSVMKLLGDDCWWAPRWMRRLQTRIGLGEIQLPDERKRPANNGS-ARPPVKAALAA 779 Query 776 ARAAGDPRPPHDPTHPLA-ESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGS 834 A A PHDPTHP A E+ RP+RS + EL +A + PS A T +Q + Sbjct 780 ATARA----PHDPTHPSAPEAARPSRSGGPARTEL------GSAQSGPSSAGTKEIQTRA 829 Query 835 S--TEPPTTRLAAAGRSVQSPASTPPPTPTPPS----------------APSAGQTRAMP 876 S ++PPTTRL A G +P + P PP+ APSAGQTRAM Sbjct 830 SQPSDPPTTRLTAPG----APPARGSSNPAPPAQTRPTTPAPPAPAPPPAPSAGQTRAMQ 885 Query 877 LAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQR-------RRGG 929 + NRS+D GDPA+PTAALPI R +G D+EAATEQLNARG + G Sbjct 886 IPTNRSSDTGGDPADPTAALPIQRPEGTDTEAATEQLNARGGQPDGGENPRPRRRGAGGA 945 Query 930 GALSAQDLLRREGRL 944 G LSAQDLLRREGRL Sbjct 946 GGLSAQDLLRREGRL 960 >gi|118616824|ref|YP_905156.1| transmembrane transport protein MmpL3 [Mycobacterium ulcerans Agy99] gi|118568934|gb|ABL03685.1| conserved transmembrane transport protein MmpL3 [Mycobacterium ulcerans Agy99] Length=960 Score = 1368 bits (3540), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/975 (75%), Positives = 812/975 (84%), Gaps = 46/975 (4%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGV VALCLGGGVFGLSLGKHVTQSGFYD+GSQSV AS+LGD+V Sbjct 1 MFAWWGRTVYRYRFIVIGVTVALCLGGGVFGLSLGKHVTQSGFYDEGSQSVTASILGDEV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-- 118 YGRDR+GHIVA+F+AP GKTV+DPAWSKK+ D+LN+F +DHPDQVLGWAGYLRA +T Sbjct 61 YGRDRTGHIVAVFKAPDGKTVNDPAWSKKITDQLNQFVKDHPDQVLGWAGYLRAPDSTSP 120 Query 119 ---GMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 GMAT DKKYTFVSIPLKGDDDDTILNNYK IAP LQ+LDGGTV+LAGL+PVAE L G Sbjct 121 VIKGMATDDKKYTFVSIPLKGDDDDTILNNYKDIAPSLQKLDGGTVQLAGLEPVAEGLIG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TIATDQRRMEVLALPLVAVVLF VFGG +AA LPVMVGGL IAGALGI+R +A+FGPVH+ Sbjct 181 TIATDQRRMEVLALPLVAVVLFLVFGGAVAACLPVMVGGLSIAGALGILRLVAVFGPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVVSLIGLGIA+DYGLF+VSRFREEIAEGYDTETAVRRTV+TAGRTV FSAVLI+AS Sbjct 241 FAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTETAVRRTVMTAGRTVAFSAVLIMAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 LL+ PQGF+KSLTYA +A+V L+A+LSIT+LPACLG+LG+HVDALGVRT FRVPFL Sbjct 301 GASLLMLPQGFVKSLTYALLAAVGLAALLSITLLPACLGVLGRHVDALGVRTAFRVPFLR 360 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 NWK+S AYLNWLADRLQ+TKTREEVEAGFWG L NRVM+RP++FA PIV+ MILL+IP+ Sbjct 361 NWKVSRAYLNWLADRLQKTKTREEVEAGFWGNLTNRVMRRPLVFAIPIVLGMILLVIPLF 420 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 LSLGG+SEKYLPP N+VRQ+QE FD+LFPGYRTNPLTLVI+++N+QPVTD QIADIRSK Sbjct 421 NLSLGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIKSTNNQPVTDQQIADIRSK 480 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 AM+I GFI+ DND +MWQER+YA G SKDPSVRVLQNGLINP DA KL ELRAITPPK Sbjct 481 AMSISGFIDQDNDADSMWQERSYAPGGSKDPSVRVLQNGLINPGDAPTKLAELRAITPPK 540 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 G+ + VGGTPALE DSIH LF MP M+VILLTTT +LMFLAFGSVVLPIKA +MSALTL Sbjct 541 GLEIFVGGTPALEQDSIHSLFENMPAMLVILLTTTTLLMFLAFGSVVLPIKAAVMSALTL 600 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 GSTMGILTWIFVDGH S LNFT TPLTAPVI L++A+ +GL+TDYEVFL+SRMVEARE Sbjct 601 GSTMGILTWIFVDGHGSGVLNFTATPLTAPVIALVVAVGYGLATDYEVFLISRMVEAREN 660 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 GMSTQEAIRIGTA TGR+ITAAAL++AVVAG+FVFSDLVMMKYLAFGLMAALLLDATVVR Sbjct 661 GMSTQEAIRIGTATTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVR 720 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVA 775 MFLVPSVMKLLGDDCWWAPRW RRLQTRIGLGEI LPDERKRP +NG ARPPV A L A Sbjct 721 MFLVPSVMKLLGDDCWWAPRWMRRLQTRIGLGEIQLPDERKRPANNGS-ARPPVKAALAA 779 Query 776 ARAAGDPRPPHDPTHPLA-ESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGS 834 A A PHDPTHP A E+ RP+RS + EL +A + PS A T +Q + Sbjct 780 ATARA----PHDPTHPSAPEAARPSRSGGPARTEL------GSAQSGPSSAGTKEIQTRA 829 Query 835 S--TEPPTTRLAAAGRSVQSPASTPPPTPTPPS----------------APSAGQTRAMP 876 S ++PPTTRL A G +P + P PP+ APSAGQTRAM Sbjct 830 SQPSDPPTTRLTAPG----APPARGSSNPAPPAQTRPTTPAPPAPAPPPAPSAGQTRAMQ 885 Query 877 LAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQR-------RRGG 929 + NRS+D GDPA+PTAALPI R +G D+EAATEQLNARG + G Sbjct 886 IPTNRSSDTGGDPADPTAALPIQRPEGTDTEAATEQLNARGGQPDGGENPRPRRRGAGGA 945 Query 930 GALSAQDLLRREGRL 944 G LSAQDLLRREGRL Sbjct 946 GGLSAQDLLRREGRL 960 >gi|240168410|ref|ZP_04747069.1| transmembrane transport protein MmpL3 [Mycobacterium kansasii ATCC 12478] Length=858 Score = 1355 bits (3507), Expect = 0.0, Method: Compositional matrix adjust. Identities = 686/871 (79%), Positives = 756/871 (87%), Gaps = 26/871 (2%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGR VYRYRFIVIGV VALCLGGGVFGLSLGKHVTQSGFYDD SQSV+AS+LGDQV Sbjct 1 MFAWWGRIVYRYRFIVIGVTVALCLGGGVFGLSLGKHVTQSGFYDDSSQSVKASILGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-- 118 YGRDR+GHIVAIF+AP GKTV+D AWSKK+ DELNRF QDHPDQV+GWAGYLRA T Sbjct 61 YGRDRTGHIVAIFKAPDGKTVNDAAWSKKITDELNRFVQDHPDQVMGWAGYLRAPDTTSP 120 Query 119 ---GMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 GMAT DKKYTFVSIPLKGDDDDTIL NYK IAP LQ+LDGGTV+LAGL+PVAEALTG Sbjct 121 VVKGMATEDKKYTFVSIPLKGDDDDTILTNYKDIAPSLQKLDGGTVQLAGLEPVAEALTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TIATDQRRMEVLALPLVAVVLF VFGG +AA LPVMVGGL IAGALGI+R +A+FGPVH+ Sbjct 181 TIATDQRRMEVLALPLVAVVLFLVFGGAVAACLPVMVGGLSIAGALGILRLVAVFGPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVVSLIGLGIA+DYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTV FSAVLI+AS Sbjct 241 FAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVAFSAVLIIAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 I LL+ PQGF+KSLTYA IA+V L+A+LSIT+LPA LG+LG+HVDALGVRT FRVPFL Sbjct 301 GISLLMLPQGFVKSLTYALIAAVGLAALLSITLLPAVLGVLGRHVDALGVRTAFRVPFLR 360 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 NWK+S AYLNWLADRLQ+TKTREEVEAGFWGKLVN VM+RP++FA PIV+ MILL+IP+ Sbjct 361 NWKVSRAYLNWLADRLQKTKTREEVEAGFWGKLVNWVMRRPLVFAIPIVLGMILLVIPLF 420 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 LSLGG+SEKYLPP NSVRQ+QE FD+LFPGYRTNPLTLVIQ++NHQPVTD Q+ADIRSK Sbjct 421 NLSLGGMSEKYLPPNNSVRQSQEHFDQLFPGYRTNPLTLVIQSTNHQPVTDQQVADIRSK 480 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 AM+I GFIEPDNDPANMWQER+ A GASKDPSVRVLQNGLINP +A+KKL ELRAITPPK Sbjct 481 AMSISGFIEPDNDPANMWQERSVAPGASKDPSVRVLQNGLINPGEAAKKLQELRAITPPK 540 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 G+ V VGGTPALE DSIH LF MP M+VILLT T +LMFLAFGSVVLPIKA +MSALTL Sbjct 541 GLEVYVGGTPALEQDSIHSLFDNMPAMLVILLTATTLLMFLAFGSVVLPIKAAVMSALTL 600 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 GSTMGILTWIFVDGH S LNFT TPLTAPVI L++A+ +GL+TDYEVFLVSRMVEARE Sbjct 601 GSTMGILTWIFVDGHGSGLLNFTATPLTAPVIALVVAVGYGLATDYEVFLVSRMVEARES 660 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 GMSTQEAIRIGTA TGR+ITAAAL++AVVAG+FVFSDLVMMKYLAFGLMAALLLDATVVR Sbjct 661 GMSTQEAIRIGTATTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVR 720 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVA 775 MFLVPSVMKLLGDDCWWAPRW RR+QTRIGLGEI LPDERKRPV++GR ARPPVTAGLVA Sbjct 721 MFLVPSVMKLLGDDCWWAPRWMRRVQTRIGLGEIQLPDERKRPVTDGRAARPPVTAGLVA 780 Query 776 ARAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSS 835 A PRPPHDPTHP S+P SS + E A + PS A T ++ I +S Sbjct 781 A----GPRPPHDPTHP---------STPESSQRGSARPEIGPAQSGPSSAGTKQIPIKAS 827 Query 836 --TEPPTTRLA------AAGRSVQSPASTPP 858 +EPPTTRL+ A GR SPA P Sbjct 828 QPSEPPTTRLSTPGKPGAPGRGSSSPAPAAP 858 >gi|41409739|ref|NP_962575.1| MmpL3 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398571|gb|AAS06191.1| MmpL3 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460053|gb|EGO38962.1| putative RND superfamily drug exporter [Mycobacterium avium subsp. paratuberculosis S397] Length=957 Score = 1277 bits (3305), Expect = 0.0, Method: Compositional matrix adjust. Identities = 685/977 (71%), Positives = 768/977 (79%), Gaps = 53/977 (5%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYR+IVIGV VALCL GGVFG+SLGKHVTQSGFYDD SQSV+ASVLGDQ Sbjct 1 MFAWWGRTVYRYRYIVIGVTVALCLLGGVFGISLGKHVTQSGFYDDASQSVKASVLGDQT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-- 118 YGRDR+ H+VA F P GKTVDD W KVV ELN+F+ DHPDQV+GWAG+L A +T Sbjct 61 YGRDRTSHVVATFTTPDGKTVDDAGWRDKVVAELNKFKADHPDQVVGWAGWLAAPDSTNP 120 Query 119 ---GMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 GM + DKK+TFVSIPLKGDDDDTILNNYKAIAPD+Q+L+GG V+LAGL+P+A ALTG Sbjct 121 VIKGMVSEDKKHTFVSIPLKGDDDDTILNNYKAIAPDMQKLNGGAVQLAGLEPIANALTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TIATDQRRMEVLA+P+VAVVLF VFGG +AAGLP +VGGL IAG+LGI+R +A+FGPVHY Sbjct 181 TIATDQRRMEVLAVPMVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVAVFGPVHY 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVVSLIGLGIAIDYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTVTFSAVLI+AS Sbjct 241 FAQPVVSLIGLGIAIDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIIAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 + LL+ PQGF+ SLTYA A+V L+A+LSIT LPACLGILG+HVDALGVRT FRVPFL Sbjct 301 SASLLVLPQGFVHSLTYAIFAAVGLAALLSITFLPACLGILGRHVDALGVRTAFRVPFLR 360 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 NWK S AYLNWLADRLQ+TKTREEVEAGFWGKLVN VM++P+ FA PI + MILL+IP+G Sbjct 361 NWKYSRAYLNWLADRLQKTKTREEVEAGFWGKLVNWVMRKPLAFAIPIAVGMILLVIPLG 420 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 LS GG+SEKYLPP N VR AQE FDK FPGYRT LT+VIQ+ NH VTD Q+ADIR++ Sbjct 421 NLSFGGMSEKYLPPNNPVRLAQEHFDKQFPGYRTEQLTVVIQSDNHSKVTDQQVADIRNR 480 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGAS-------------KDPSVRVLQNGLINPADAS 522 IGGF + WQER A KD SVRV+QNGL N DA+ Sbjct 481 ISGIGGFTD------KTWQERPCPTIAGNPCVPGPNGTTVPKDGSVRVIQNGLANRNDAA 534 Query 523 KKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVV 582 KK+ ELRA+ PPKG+ + VGGTPALE DSIH LF K PLM+V+LL T++LMFLAFGSVV Sbjct 535 KKIAELRAVNPPKGLNLYVGGTPALEQDSIHSLFDKAPLMLVLLLGATLLLMFLAFGSVV 594 Query 583 LPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYE 642 LPIKA LMSALTLGSTMGILTWIFVDGH S LNFTPTPL VI L++A+ FGL+TDYE Sbjct 595 LPIKAVLMSALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDYE 654 Query 643 VFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFG 702 VFLVSRMVEARERGMST EAIRIGTA TGR+ITAAA+++AVVA +FVFSDLV+MKYLAFG Sbjct 655 VFLVSRMVEARERGMSTAEAIRIGTATTGRLITAAAMVLAVVASSFVFSDLVLMKYLAFG 714 Query 703 LMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNG 762 LMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQ +IGLGEI LPDERKRP NG Sbjct 715 LMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQNKIGLGEIDLPDERKRPTLNG 774 Query 763 RPARPPVTAGLVAARAAGDPRPPHDPTHPLAESP-RPARSSPAS-SPELTPALEATAAPA 820 RPARPPV A LVAA PRPPHDPTHP A P RPAR +PA P PA T PA Sbjct 775 RPARPPVAASLVAAA----PRPPHDPTHPAAPEPSRPARPAPAEPRPAQEPAASTTRIPA 830 Query 821 APSGASTTRMQIGSSTEPPTTRLAAAGR-SVQSPASTPPPTPTPPSA----PSAGQTRAM 875 P+ TE TTR AA G Q P P TP P A PS QTRA+ Sbjct 831 RPN----------QPTEAQTTRFAAPGAPGRQRPPEPRPATPQRPPAQAAPPSGDQTRAI 880 Query 876 PLAANR--STDAAGDPAEPTAALPIIRSD---GDDSEAATEQLNARG---TSDKTRQRRR 927 P+ NR D+ D AEPT ALP +R++ G +S+AA +Q NARG D RQRRR Sbjct 881 PVPGNRPDDGDSDADAAEPTTALPKMRAEGSGGSESDAAGDQANARGQGENGDPARQRRR 940 Query 928 GGGALSAQDLLRREGRL 944 GG LSAQDLLRREGRL Sbjct 941 AGGGLSAQDLLRREGRL 957 >gi|289760309|ref|ZP_06519687.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis T85] gi|289715873|gb|EFD79885.1| transmembrane transporter mmpL3 [Mycobacterium tuberculosis T85] Length=680 Score = 1277 bits (3304), Expect = 0.0, Method: Compositional matrix adjust. Identities = 659/680 (97%), Positives = 661/680 (98%), Gaps = 1/680 (0%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM Sbjct 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD Sbjct 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV Sbjct 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL Sbjct 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS Sbjct 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG Sbjct 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG Sbjct 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL Sbjct 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG Sbjct 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVE-ARERGMST 659 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSR AR R + Sbjct 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRDGRGARARHVDP 660 Query 660 QEAIRIGTAATGRIITAAAL 679 GRIITAAAL Sbjct 661 GGDPGSAPQPPGRIITAAAL 680 Score = 57.4 bits (137), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/169 (28%), Positives = 84/169 (50%), Gaps = 18/169 (10%) Query 562 MVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDG--HFSKWLNFTP 619 M V+ L V++F FG V+ ++ L + +GI+ ++ + G H+ Sbjct 184 MEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY-------- 235 Query 620 TPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIIT-AAA 678 PV+ LI G++ DY +F+VSR E G T+ A+R GR +T +A Sbjct 236 --FAQPVVSLI---GLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAV 290 Query 679 LIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLG 727 LIVA G +F +K L + +A+++L A ++ + ++P+ + +LG Sbjct 291 LIVASAIGLLLFPQ-GFLKSLTYATIASVMLSA-ILSITVLPACLGILG 337 >gi|342859338|ref|ZP_08715992.1| MmpL3 [Mycobacterium colombiense CECT 3035] gi|342133579|gb|EGT86782.1| MmpL3 [Mycobacterium colombiense CECT 3035] Length=945 Score = 1254 bits (3246), Expect = 0.0, Method: Compositional matrix adjust. Identities = 672/969 (70%), Positives = 755/969 (78%), Gaps = 57/969 (5%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 +YRYR+IVIGV VALCL GGVFG+SLGKHVTQSGFYDDGSQSV+ASVLGDQ YGRDR+ H Sbjct 1 MYRYRYIVIGVTVALCLLGGVFGISLGKHVTQSGFYDDGSQSVKASVLGDQTYGRDRTSH 60 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-----GMATA 123 +VA F AP GKTVDD AW K++ ELN+F+ DHPDQV+GWAG+L A +T GM + Sbjct 61 VVATFTAPNGKTVDDAAWRDKIIGELNKFKADHPDQVVGWAGWLAAPDSTNPVIKGMVSE 120 Query 124 DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRR 183 DKK+TFVSIPLKG+DDD+ILNNYK I P+LQ+L+GGTV+LAGL+P+A ALTGTIATDQRR Sbjct 121 DKKHTFVSIPLKGNDDDSILNNYKTIQPELQKLNGGTVQLAGLEPIANALTGTIATDQRR 180 Query 184 MEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSL 243 MEVLA+P+VAVVLF VFGG +AAGLP +VGGL IAG+LGI+R +A+FGPVHYFAQPVVSL Sbjct 181 MEVLAVPMVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVAVFGPVHYFAQPVVSL 240 Query 244 IGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFP 303 IGLGIAIDYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTVTFSAVLI+AS+ LL+ P Sbjct 241 IGLGIAIDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIIASSASLLVLP 300 Query 304 QGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAY 363 QGF+ SLTYA A+V L+A+LSIT LPACL ILG+HVDALGVRT FRVPFL NWK S AY Sbjct 301 QGFVHSLTYAIFAAVGLAALLSITFLPACLAILGRHVDALGVRTAFRVPFLRNWKYSRAY 360 Query 364 LNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGIS 423 LNWLADRLQ+TKTREEVEAGFWGKLVN VMKRP+ FA PI + MILL+IP+G LS GG+S Sbjct 361 LNWLADRLQKTKTREEVEAGFWGKLVNWVMKRPLAFAIPIAVGMILLVIPLGNLSFGGMS 420 Query 424 EKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFI 483 EKYLPP N VR AQE FDK FPGYRT LT+VIQ++N VTD Q+ADIR++ IGGF Sbjct 421 EKYLPPDNPVRLAQEHFDKQFPGYRTEQLTMVIQSTNGSKVTDQQVADIRNRISGIGGFT 480 Query 484 EPDNDPANMWQERAYAVGAS-------------KDPSVRVLQNGLINPADASKKLTELRA 530 + WQER A KD SVRV+QNGL+N DA+KKL ELR+ Sbjct 481 D------KTWQERPCPTIAGNPCVAGPNGTTVPKDDSVRVIQNGLVNKNDAAKKLAELRS 534 Query 531 ITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLM 590 + PPKG+ + VGGTPALE DSIH L K PLM+V+LL+ T++LMFLAFGSVVLP+KA LM Sbjct 535 VAPPKGLNLYVGGTPALEQDSIHSLAEKGPLMLVLLLSATLLLMFLAFGSVVLPVKAVLM 594 Query 591 SALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMV 650 SALTLGSTMGILTWIFVDGH S LNFTPTPL VI L++A+ FGL+TDYEVFLVSRMV Sbjct 595 SALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDYEVFLVSRMV 654 Query 651 EARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLD 710 EARERGMST EAIRIGTA TGR+ITAAAL++AVVA +FVFSDLV+MKYLAFGLMAALLLD Sbjct 655 EARERGMSTTEAIRIGTATTGRLITAAALVLAVVASSFVFSDLVLMKYLAFGLMAALLLD 714 Query 711 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVT 770 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQ +IGLGEI LPDERKRP NGRPARPPV Sbjct 715 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQNKIGLGEIDLPDERKRPTLNGRPARPPVA 774 Query 771 AGLVAARAAGDPRPPHDPTHPLAESP-RPARSSPASSPELTPALEATAAPAAPSGASTTR 829 A LVAA PRPPHDPTHP A P RPAR + P PA T PA PS Sbjct 775 ASLVAAA----PRPPHDPTHPGALEPSRPARPT-DPRPAQEPAASTTRIPARPS------ 823 Query 830 MQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPP-----------SAPSAGQTRAMPLA 878 TE TTR AA GR PA P P + PS QTRA+P+ Sbjct 824 ----QPTEAKTTRFAAPGR--DRPAEPRPANSAPQAAQRPPAPGPAAPPSGDQTRAIPVP 877 Query 879 ANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARG---TSDKTRQRRRGGGALSAQ 935 NRS D D EPT ALP +R +G D AATEQ NARG D RQRRR GG LSA Sbjct 878 GNRSDD-NNDEVEPTTALPKLRPEGTDPNAATEQANARGQGENGDPARQRRRSGGGLSAA 936 Query 936 DLLRREGRL 944 DLLRREGRL Sbjct 937 DLLRREGRL 945 >gi|118464977|ref|YP_884089.1| MmpL3 protein [Mycobacterium avium 104] gi|118166264|gb|ABK67161.1| MmpL3 protein [Mycobacterium avium 104] Length=949 Score = 1246 bits (3225), Expect = 0.0, Method: Compositional matrix adjust. Identities = 673/969 (70%), Positives = 759/969 (79%), Gaps = 53/969 (5%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 +YRYR+IVIGV VALCL GGVFG+SLGKHVTQSGFYDD SQSV+ASVLGDQ YGRDR+ H Sbjct 1 MYRYRYIVIGVTVALCLLGGVFGISLGKHVTQSGFYDDASQSVKASVLGDQTYGRDRTSH 60 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-----GMATA 123 +VA F P GKTVDD W KVV ELN+F+ DHPDQV+GWAG+L A +T GM + Sbjct 61 VVATFTTPDGKTVDDAGWRDKVVAELNKFKADHPDQVVGWAGWLAAPDSTNPVIKGMVSE 120 Query 124 DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRR 183 DKK+TFVSIPLKGDDDDTILNNYKAIAPD+Q+L+GG V+LAGL+P+A ALTGTIATDQRR Sbjct 121 DKKHTFVSIPLKGDDDDTILNNYKAIAPDMQKLNGGAVQLAGLEPIANALTGTIATDQRR 180 Query 184 MEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSL 243 MEVLA+P+VAVVLF VFGG +AAGLP +VGGL IAG+LGI+R +A+FGPVHYFAQPVVSL Sbjct 181 MEVLAVPMVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVAVFGPVHYFAQPVVSL 240 Query 244 IGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFP 303 IGLGIAIDYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTVTFSAVLI+AS+ LL+ P Sbjct 241 IGLGIAIDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIIASSASLLVLP 300 Query 304 QGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAY 363 QGF+ SLTYA A+V L+A+LSIT LPACLGILG+HVDALGVRT FRVPFL NWK S AY Sbjct 301 QGFVHSLTYAIFAAVGLAALLSITFLPACLGILGRHVDALGVRTAFRVPFLRNWKYSRAY 360 Query 364 LNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGIS 423 LNWLADRLQ+TKTREEVEAGFWGKLVN VM++P+ FA PI + MILL+IP+G LS GG+S Sbjct 361 LNWLADRLQKTKTREEVEAGFWGKLVNWVMRKPLAFAIPIAVGMILLVIPLGNLSFGGMS 420 Query 424 EKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFI 483 EKYLPP N VR AQE FDK FPGYRT LT+VIQ+ NH VTD Q+ADIR++ IGGF Sbjct 421 EKYLPPNNPVRLAQEHFDKQFPGYRTEQLTVVIQSDNHSKVTDQQVADIRNRISGIGGFT 480 Query 484 EPDNDPANMWQERAYAVGAS-------------KDPSVRVLQNGLINPADASKKLTELRA 530 + WQER A KD SVRV+QNGL N DA+KK+ ELRA Sbjct 481 D------KTWQERPCPTIAGNPCIPGPNGTTVPKDGSVRVIQNGLANRNDAAKKIAELRA 534 Query 531 ITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLM 590 + PPKG+ + VGGTPALE DSIH LF K PLM+V+LL T++LMFLAFGSVVLPIKA LM Sbjct 535 VNPPKGLNLYVGGTPALEQDSIHSLFDKAPLMLVLLLGATLLLMFLAFGSVVLPIKAVLM 594 Query 591 SALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMV 650 SALTLGSTMGILTWIFVDGH S LNFTPTPL VI L++A+ FGL+TDYEVFLVSRMV Sbjct 595 SALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDYEVFLVSRMV 654 Query 651 EARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLD 710 EARERGMST EAIRIGTA TGR+ITAAA+++AVVA +FVFSDLV+MKYLAFGLMAALLLD Sbjct 655 EARERGMSTAEAIRIGTATTGRLITAAAMVLAVVASSFVFSDLVLMKYLAFGLMAALLLD 714 Query 711 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVT 770 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQ +IGLGEI LPDERKRP NGRPARPPV Sbjct 715 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQNKIGLGEIDLPDERKRPTLNGRPARPPVA 774 Query 771 AGLVAARAAGDPRPPHDPTHPLAESP-RPARSSPAS-SPELTPALEATAAPAAPSGASTT 828 A LVA PRPPHDPTHP A P RPAR +PA P PA T PA P+ Sbjct 775 ASLVATA----PRPPHDPTHPAAPEPSRPARPAPAEPRPAQEPAASTTRIPARPN----- 825 Query 829 RMQIGSSTEPPTTRLAAAG-----RSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANR-- 881 TE TTR AA G R + + P PT + PS QTRA+P+ NR Sbjct 826 -----QPTEAQTTRFAAPGAPGRQRPAEPRPAPPQRPPTQAAPPSGDQTRAIPVPGNRPD 880 Query 882 STDAAGDPAEPTAALPIIRSD---GDDSEAATEQLNARG---TSDKTRQRRRGGGALSAQ 935 D+ D AEPT ALP +R++ G +S+AA +Q NARG D RQRRR GG LSAQ Sbjct 881 DGDSDADAAEPTTALPKMRAEGSGGSESDAAGDQANARGQGENGDPARQRRRAGGGLSAQ 940 Query 936 DLLRREGRL 944 DLLRREGRL Sbjct 941 DLLRREGRL 949 >gi|120401223|ref|YP_951052.1| large membrane protein [Mycobacterium vanbaalenii PYR-1] gi|119954041|gb|ABM11046.1| conserved large membrane protein [Mycobacterium vanbaalenii PYR-1] Length=1013 Score = 1189 bits (3076), Expect = 0.0, Method: Compositional matrix adjust. Identities = 634/1032 (62%), Positives = 746/1032 (73%), Gaps = 107/1032 (10%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVY+YR+IVIGVMVALCLGGGV+G+SLG+HVTQSGFYDDGSQSV ASV+ D+V Sbjct 1 MFAWWGRTVYQYRYIVIGVMVALCLGGGVYGISLGQHVTQSGFYDDGSQSVHASVVSDEV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATG- 119 YGRDR+ H+VAI P G+ VD+P W +KV ELN +H D+++ W G+LRA +T Sbjct 61 YGRDRTSHVVAILTPPDGEKVDNPEWMEKVTGELNDVVAEHEDRIVSWVGWLRAPDSTAE 120 Query 120 ----MATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 M TAD TFVSIPLKGDDDD IL NY+A+ PDL +++ G +KLAGLQP+A LTG Sbjct 121 TVQQMKTADGSKTFVSIPLKGDDDDEILKNYQAVEPDLLKINDGNIKLAGLQPLASELTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TI DQ+R EV A+PLVAVVLFFVFGGVIAA LP ++GGL IAGALGIMR A F PVH+ Sbjct 181 TIGEDQKRAEVAAIPLVAVVLFFVFGGVIAATLPAIIGGLTIAGALGIMRIFAEFMPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVV+L+GLGIAIDYGLF+VSRFREEIAEGYDTE AVRRTV+T+GRTV FSAV++VAS Sbjct 241 FAQPVVTLMGLGIAIDYGLFMVSRFREEIAEGYDTEAAVRRTVMTSGRTVMFSAVILVAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 ++ LLLFPQGFLKS+TYA IASVML+AILS+TVLPA ILG++VDALGVRTL RVPF Sbjct 301 SVPLLLFPQGFLKSITYAIIASVMLAAILSVTVLPAAFSILGRNVDALGVRTLLRVPFFR 360 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 NWK YL WLA++ Q+TKTR EVE GFWG+LVN VMKRP+ FAAPI+I+MILL+IP+G Sbjct 361 NWKPMRVYLEWLAEKTQKTKTRAEVEKGFWGRLVNVVMKRPIAFAAPILIVMILLVIPLG 420 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 +L+LGGISEKYLPP NSVR AQE+FD+ FP +RT PLTLV++ + QPVTD Q+A++R+K Sbjct 421 QLALGGISEKYLPPDNSVRIAQEDFDRTFPTFRTEPLTLVLERQDGQPVTDQQLAEVRAK 480 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 AM GFIE +NDP MWQERA +KDPSVRV+QNGL++ DAS+K+ ELR+I PP+ Sbjct 481 AMTFSGFIEDNNDPTKMWQERAAQDSGTKDPSVRVIQNGLVDRNDASQKIEELRSIQPPR 540 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 G+ + VGGTPALE DSIH LF K+PLMV++L+ TT VLMFLAFGS+VLPIKA LMSALTL Sbjct 541 GVQISVGGTPALEQDSIHSLFDKLPLMVLVLIVTTTVLMFLAFGSIVLPIKAALMSALTL 600 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 GSTMGILTW+FVDGH S +N+TP PL AP+IGLIIA+++GLSTDYEVFLVSRMVEARER Sbjct 601 GSTMGILTWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARER 660 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 GMST EAIRIGTA TGR+IT AAL++AVVAGAFVFSDLVMMKYLAFGL+ ALLLDAT++R Sbjct 661 GMSTAEAIRIGTATTGRLITGAALVLAVVAGAFVFSDLVMMKYLAFGLLIALLLDATIIR 720 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPV--SNGRPARPPVTAGL 773 MFLVP++MKLLGDDCWWAPRW +R+Q ++GLGE LPDERKRP N PA V AG Sbjct 721 MFLVPAIMKLLGDDCWWAPRWMKRVQEKLGLGETELPDERKRPTVRENPAPAEALVGAGG 780 Query 774 VAARAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRM--- 830 A P PPHDPTHP A RP P T + A PS A TTR+ Sbjct 781 PPVAAPPRPLPPHDPTHP-APGGRP--------PGATTRMTAPPRAGDPSAAGTTRLPSA 831 Query 831 ----QIGSSTEPPTTRLAAAGRSVQSPAS------------------------------- 855 EP TTRL+ A +V++ S Sbjct 832 PPRPPAAPEEEPQTTRLSIAKNAVRNAVSTAAAAAQRATERPASGPPAPPAPSAPPARED 891 Query 856 -----------------TPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPI 898 T P P PSA TRAMP T AAG+ EPT A+P Sbjct 892 REIESWLGDLRGSRASGTAAANPPQPLRPSAEPTRAMP-----DTGAAGN--EPTTAIPA 944 Query 899 IRS-----------DGDDS---------------EAATEQLNARGTSDKTRQRRRGGGAL 932 R D DDS +AATE+LN R + T RRGG L Sbjct 945 QRESERHRESARHDDSDDSAASTRAIPTARQSDADAATEKLNTRPDDEAT---RRGGKGL 1001 Query 933 SAQDLLRREGRL 944 SAQDLLRREGRL Sbjct 1002 SAQDLLRREGRL 1013 >gi|296167426|ref|ZP_06849826.1| transmembrane transport protein MmpL3 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897216|gb|EFG76822.1| transmembrane transport protein MmpL3 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=789 Score = 1176 bits (3043), Expect = 0.0, Method: Compositional matrix adjust. Identities = 602/799 (76%), Positives = 680/799 (86%), Gaps = 28/799 (3%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 +YRYR+IVIGV VALCL GG+FG+SLGKHVTQSGFYD+GSQSV+ASVLGDQ YGRDR+ H Sbjct 1 MYRYRYIVIGVTVALCLLGGLFGMSLGKHVTQSGFYDEGSQSVKASVLGDQTYGRDRTSH 60 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-----GMATA 123 IVA F AP+GKTVDD AW K+V +LN+F+ DHPDQV+GWAG+L A +T GM + Sbjct 61 IVATFTAPSGKTVDDAAWRDKIVGQLNKFKADHPDQVVGWAGWLAAPDSTNPLIKGMVSG 120 Query 124 DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRR 183 D+K+TFVSIPLKGDDDD+ILNNYK IAPDLQ+LDGGTV+LAGL+P+A ALTGTIATDQRR Sbjct 121 DRKHTFVSIPLKGDDDDSILNNYKDIAPDLQKLDGGTVQLAGLEPIANALTGTIATDQRR 180 Query 184 MEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSL 243 MEVLA+P+VAVVLF VFGG +AAGLP +VGGL IAG+LGI+R +A+FGPVHYFAQPVVSL Sbjct 181 MEVLAVPMVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVAVFGPVHYFAQPVVSL 240 Query 244 IGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFP 303 IGLGIAIDYGLF+VSRFREEIAEGYDTETAVRRTV+TAGRTVTFSAVLI+AS+ LL+ P Sbjct 241 IGLGIAIDYGLFVVSRFREEIAEGYDTETAVRRTVMTAGRTVTFSAVLIIASSASLLVLP 300 Query 304 QGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAY 363 QGF+ SLTYA A+V L+A+LSIT LPACLGILG+HVDALGVRT FRVPFL NWK S AY Sbjct 301 QGFVHSLTYAIFAAVGLAALLSITFLPACLGILGRHVDALGVRTAFRVPFLRNWKYSRAY 360 Query 364 LNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGIS 423 LNWLADRLQ+TKTREEVEAGFWGKLVN VMKRP+ FA PI + MILL+IP+G LS GG+S Sbjct 361 LNWLADRLQKTKTREEVEAGFWGKLVNWVMKRPLAFAIPIAVGMILLVIPLGNLSFGGMS 420 Query 424 EKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFI 483 EKYLPPTN VRQAQE FDKLFPGYRT LT+VIQ++NH VTD Q+ADIR++ +IGGF Sbjct 421 EKYLPPTNPVRQAQEHFDKLFPGYRTEQLTMVIQSTNHSKVTDQQVADIRNRISSIGGFT 480 Query 484 EPDNDPANMWQERAYAVGAS-------------KDPSVRVLQNGLINPADASKKLTELRA 530 + W+ER A KD SVRV+QNGL+N DA+KK++ELRA Sbjct 481 D------KTWEERPCPTIAGNPCVAGPNGTTVPKDGSVRVIQNGLVNKNDAAKKISELRA 534 Query 531 ITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLM 590 I+PPKG+ + VGGTPALE DSIH LF K PLM+V+LL T++LMFLAFGSVVLP+KA LM Sbjct 535 ISPPKGLNLYVGGTPALEQDSIHSLFDKAPLMLVLLLGATLLLMFLAFGSVVLPVKAVLM 594 Query 591 SALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMV 650 SALTLGSTMGILTWIFVDGH S LNFTPTPL VI L++A+ FGL+TDYEVFLVSRMV Sbjct 595 SALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDYEVFLVSRMV 654 Query 651 EARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLD 710 EARERGMST EAIRIGTA TGR+ITAAAL++AVVA +FVFSDLV+MKYLAFGLMAALLLD Sbjct 655 EARERGMSTAEAIRIGTATTGRLITAAALVLAVVASSFVFSDLVLMKYLAFGLMAALLLD 714 Query 711 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVT 770 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQ RIGLGEI LPDERKRP NGRPARPPV Sbjct 715 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQNRIGLGEIDLPDERKRPTLNGRPARPPVA 774 Query 771 AGLVAARAAGDPRPPHDPT 789 A L AA PRPPHDPT Sbjct 775 ASL----AAAPPRPPHDPT 789 >gi|333988809|ref|YP_004521423.1| transporter [Mycobacterium sp. JDM601] gi|333484776|gb|AEF34168.1| transmembrane transport protein MmpL3 [Mycobacterium sp. JDM601] Length=968 Score = 1150 bits (2976), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/984 (64%), Positives = 735/984 (75%), Gaps = 58/984 (5%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVYRYRFIVIGVMVALCLGGGV+G+SLG HVTQSGFYDDGSQSVQASVLGD+V Sbjct 1 MFAWWGRTVYRYRFIVIGVMVALCLGGGVYGMSLGDHVTQSGFYDDGSQSVQASVLGDEV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATG- 119 YGRDR+ H+VA+F AP G+TVDD W V + LN+ + DHPDQ+L W GY +A Sbjct 61 YGRDRTSHVVAVFTAPKGETVDDKQWFDGVKNGLNKVKDDHPDQILSWVGYFTNPEALAT 120 Query 120 MATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIAT 179 MA ADKK+ F SI LKGDDDDTIL NY+A P LQ LDGG V+L GLQP+A ALTGTIA+ Sbjct 121 MADADKKHAFASIQLKGDDDDTILKNYQAAEPALQELDGGKVELGGLQPIASALTGTIAS 180 Query 180 DQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQP 239 D++RMEVLALPLVAVVLFFVFGGV+AA LPV+VGGL IAGA GI+RF A+FGPVH+FAQP Sbjct 181 DEKRMEVLALPLVAVVLFFVFGGVVAASLPVIVGGLSIAGATGILRFAAMFGPVHFFAQP 240 Query 240 VVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGL 299 VVSLIGLGIAIDYGLF+VSRFREEIAEGYDTE AVRR+V+TAGRTV FSAVLI+AS+ L Sbjct 241 VVSLIGLGIAIDYGLFVVSRFREEIAEGYDTEAAVRRSVMTAGRTVVFSAVLIIASSASL 300 Query 300 LLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKI 359 L+ PQGF+ SLTYA ASV L+A+LSIT+LPA LG+LG +VDALGVRTL+R+PFL +W+ Sbjct 301 LVLPQGFVHSLTYAIFASVGLAALLSITLLPAILGVLGTNVDALGVRTLYRIPFLRDWEF 360 Query 360 SAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSL 419 S + W A++ Q+TKTREEVEAGFWGKLVN VM+RP+ FA PIV+ MILLIIP+GKL+ Sbjct 361 SNRIIGWFAEKTQKTKTREEVEAGFWGKLVNFVMQRPLAFAIPIVVGMILLIIPLGKLTF 420 Query 420 GGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAI 479 GG+SEKYLPP N+ R AQE FD++FPG+RT LTLVI+++ +PVTD Q+ADIR++AM+I Sbjct 421 GGMSEKYLPPDNTARMAQEHFDEIFPGFRTEKLTLVIKSTADKPVTDQQVADIRNRAMSI 480 Query 480 GGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITV 539 GF+ PD++P +MW+ER Y GASKD S RV++NGL+N DA++K+ LR+++ PKG++V Sbjct 481 SGFVVPDDNPDDMWKERPYLPGASKDDSTRVIENGLVNRNDAAQKIKALRSLSTPKGLSV 540 Query 540 LVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTM 599 LVGGTPALE DSIH + + PLM+VILLTTT +LMFLAFGS+VLP+KA +MSALT+GSTM Sbjct 541 LVGGTPALEQDSIHTMIDRGPLMLVILLTTTTLLMFLAFGSLVLPLKAAVMSALTIGSTM 600 Query 600 GILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMST 659 GILTWIFVDGH + +NFTPTPL +I L++A+ +GL+TDYEVFLVSRMVEARE GMST Sbjct 601 GILTWIFVDGHGAGLMNFTPTPLMVVIIALVVAVGWGLATDYEVFLVSRMVEARESGMST 660 Query 660 QEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLV 719 EAIRIGTA TGR+ITAAALI+AVVA +FVFSDLVMMKYLAFGLMAALLLDATV+RMFLV Sbjct 661 SEAIRIGTATTGRLITAAALILAVVAASFVFSDLVMMKYLAFGLMAALLLDATVIRMFLV 720 Query 720 PSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAA 779 PSVMKLLGDDCWWAPRW +R+Q RIGLGEI LPDERKR V+ P TA AA A Sbjct 721 PSVMKLLGDDCWWAPRWMKRIQNRIGLGEIRLPDERKRRVTRPSAPAPLATAPAGAAPAR 780 Query 780 GDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPP 839 HDPTHP A + P T L +PSGA T+R+ G E P Sbjct 781 PS----HDPTHPTAGG--------QARPRATEQLPTRPVTGSPSGARTSRINAGPP-EAP 827 Query 840 TTRLAAA------------------------------GRSVQSPASTPPPTPTPPSAPSA 869 TTR AA GR SP S P P PS Sbjct 828 TTRFQAADPVTERVESPAEGPAGGDREIESWLGELRGGRDAGSPRSRGRQDPAEPR-PSD 886 Query 870 GQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNA-RGTSDK------- 921 +TR++P A D PT A+P+ ATE+L A R DK Sbjct 887 ERTRSLPKPAGPPEDTEN---APTTAIPVQGDPAGPDSPATEKLTAPRDQGDKGDKGDKS 943 Query 922 --TRQRRRGGGALSAQDLLRREGR 943 QRR G LSA +LLRREGR Sbjct 944 GDNPQRRGAAGGLSAAELLRREGR 967 >gi|254822115|ref|ZP_05227116.1| MmpL3 protein [Mycobacterium intracellulare ATCC 13950] Length=768 Score = 1126 bits (2913), Expect = 0.0, Method: Compositional matrix adjust. Identities = 579/774 (75%), Positives = 657/774 (85%), Gaps = 24/774 (3%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 +YRYR+IVIGV VALCL GGVFG+SLGKHVTQSGFYDDGSQSV+ASVLGD+ YGRDR+ H Sbjct 1 MYRYRYIVIGVTVALCLLGGVFGISLGKHVTQSGFYDDGSQSVKASVLGDETYGRDRTSH 60 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQA-----TGMATA 123 +VA F AP GKTV+DPAW KVV ELN+F+ DHPDQV+GWAG+L A + GM + Sbjct 61 VVATFTAPDGKTVEDPAWRDKVVAELNKFKADHPDQVVGWAGWLAAPNSDNPVIKGMVSE 120 Query 124 DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRR 183 DKK+TFVS+PLKGDDDD+ILNNYKAIAP LQ+L GG V+LAGL+P+A ALTGTIATDQRR Sbjct 121 DKKHTFVSVPLKGDDDDSILNNYKAIAPGLQKLGGGNVELAGLEPIANALTGTIATDQRR 180 Query 184 MEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSL 243 MEVLA+PLVAVVLF VFGG +AAGLP +VGGL IAG+LGI+R +++FGPVH+FAQPVVSL Sbjct 181 MEVLAVPLVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVSLFGPVHFFAQPVVSL 240 Query 244 IGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFP 303 IGLGIAIDYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTVTFSAVLI+AS+ LL+ P Sbjct 241 IGLGIAIDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIIASSASLLVLP 300 Query 304 QGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAY 363 QGF+ SLTYA A+V L+A+LSIT LPACLGILG+HVDALGVRT FRVPFL NWK S AY Sbjct 301 QGFVHSLTYAIFAAVGLAALLSITFLPACLGILGRHVDALGVRTAFRVPFLRNWKYSRAY 360 Query 364 LNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGIS 423 LNWLADRLQ+TKTREEVEAGFWGKLVN VMKRP+ FA PI + MILL+IP+G LS GG+S Sbjct 361 LNWLADRLQKTKTREEVEAGFWGKLVNWVMKRPLAFAIPIAVGMILLVIPLGNLSFGGMS 420 Query 424 EKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFI 483 EKYLPP N+VR AQE FDK FPGYRT LT+VIQ+ NH VTD Q+ADIR++ +IGGF Sbjct 421 EKYLPPDNAVRLAQEHFDKRFPGYRTEQLTVVIQSDNHSKVTDQQVADIRNRISSIGGFT 480 Query 484 EPDNDPANMWQERAYAVGAS-------------KDPSVRVLQNGLINPADASKKLTELRA 530 + W+ERA A KD SVRV+QNGL+N DA+KK+TELRA Sbjct 481 D------KQWEERACPTIAGNPCVAGPNGTTVPKDGSVRVIQNGLVNKNDAAKKITELRA 534 Query 531 ITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLM 590 + PPKG+ + VGGTPALE DSIH LF K PLM+V+LL T++LMFLAFGSVVLP+KA +M Sbjct 535 VNPPKGLNLYVGGTPALEQDSIHSLFDKAPLMLVLLLGATMLLMFLAFGSVVLPVKAAVM 594 Query 591 SALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMV 650 SALTLGSTMGILTWIFVDGH S LNFTPTPL VI L++A+ FGL+TDYEVFLVSRMV Sbjct 595 SALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDYEVFLVSRMV 654 Query 651 EARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLD 710 EARERGMST EAIRIGTA TGR+ITAAAL++AVVAG+FVFSDLV+MKYLAFGLMAALLLD Sbjct 655 EARERGMSTAEAIRIGTATTGRLITAAALVLAVVAGSFVFSDLVLMKYLAFGLMAALLLD 714 Query 711 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRP 764 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQ +IGLGEI LPDERKRP NGRP Sbjct 715 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQNKIGLGEIDLPDERKRPTLNGRP 768 >gi|254777407|ref|ZP_05218923.1| MmpL3 protein [Mycobacterium avium subsp. avium ATCC 25291] Length=760 Score = 1115 bits (2884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 572/766 (75%), Positives = 644/766 (85%), Gaps = 24/766 (3%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 +YRYR+IVIGV VALCL GGVFG+SLGKHVTQSGFYDD SQSV+ASVLGDQ YGRDR+ H Sbjct 1 MYRYRYIVIGVTVALCLLGGVFGISLGKHVTQSGFYDDASQSVKASVLGDQTYGRDRTSH 60 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQAT-----GMATA 123 +VA F P GKTVDD W KVV ELN+F+ DHPDQV+GWAG+L A +T GM + Sbjct 61 VVATFTTPDGKTVDDAGWRDKVVAELNKFKADHPDQVVGWAGWLAAPDSTNPVIKGMVSE 120 Query 124 DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATDQRR 183 DKK+TFVSIPLKGDDDDTILNNYKAIAPD+Q+L+GG V+LAGL+P+A ALTGTIATDQRR Sbjct 121 DKKHTFVSIPLKGDDDDTILNNYKAIAPDMQKLNGGAVQLAGLEPIANALTGTIATDQRR 180 Query 184 MEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSL 243 MEVLA+P+VAVVLF VFGG +AAGLP +VGGL IAG+LGI+R +A+FGPVHYFAQPVVSL Sbjct 181 MEVLAVPMVAVVLFLVFGGAVAAGLPAIVGGLSIAGSLGILRLVAVFGPVHYFAQPVVSL 240 Query 244 IGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFP 303 IGLGIAIDYGLF+VSRFREEIAEGYDTE AVRRTV+TAGRTVTFSAVLI+AS+ LL+ P Sbjct 241 IGLGIAIDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIIASSASLLVLP 300 Query 304 QGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAY 363 QGF+ SLTYA A+V L+A+LSIT LPACLGILG+HVDALGVRT FRVPFL NWK S AY Sbjct 301 QGFVHSLTYAIFAAVGLAALLSITFLPACLGILGRHVDALGVRTAFRVPFLRNWKYSRAY 360 Query 364 LNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGIS 423 LNWLADRLQ+TKTREEVEAGFWGKLVN VM++P+ FA PI + MILL+IP+G LS GG+S Sbjct 361 LNWLADRLQKTKTREEVEAGFWGKLVNWVMRKPLAFAIPIAVGMILLVIPLGNLSFGGMS 420 Query 424 EKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFI 483 EKYLPP N VR AQE FDK FPGYRT LT+VIQ+ NH VTD Q+ADIR++ IGGF Sbjct 421 EKYLPPNNPVRLAQEHFDKQFPGYRTEQLTVVIQSDNHSKVTDQQVADIRNRISGIGGFT 480 Query 484 EPDNDPANMWQERAYAVGAS-------------KDPSVRVLQNGLINPADASKKLTELRA 530 + WQER A KD SVRV+QNGL N DA+KK+ ELRA Sbjct 481 D------KTWQERPCPTIAGNPCIPGPNGTTVPKDGSVRVIQNGLANRNDAAKKIAELRA 534 Query 531 ITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLM 590 + PPKG+ + VGGTPALE DSIH LF K PLM+V+LL T++LMFLAFGSVVLPIKA LM Sbjct 535 VNPPKGLNLYVGGTPALEQDSIHSLFDKAPLMLVLLLGATLLLMFLAFGSVVLPIKAVLM 594 Query 591 SALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMV 650 SALTLGSTMGILTWIFVDGH S LNFTPTPL VI L++A+ FGL+TDYEVFLVSRMV Sbjct 595 SALTLGSTMGILTWIFVDGHLSGVLNFTPTPLMVVVIALVVAVGFGLATDYEVFLVSRMV 654 Query 651 EARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLD 710 EARERGMST EAIRIGTA TGR+ITAAA+++AVVA +FVFSDLV+MKYLAFGLMAALLLD Sbjct 655 EARERGMSTAEAIRIGTATTGRLITAAAMVLAVVASSFVFSDLVLMKYLAFGLMAALLLD 714 Query 711 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERK 756 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQ +IGLGEI LPDERK Sbjct 715 ATVVRMFLVPSVMKLLGDDCWWAPRWARRLQNKIGLGEIDLPDERK 760 >gi|169631582|ref|YP_001705231.1| putative membrane protein MmpL [Mycobacterium abscessus ATCC 19977] gi|169243549|emb|CAM64577.1| Putative membrane protein, MmpL [Mycobacterium abscessus] Length=1001 Score = 1038 bits (2683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 571/1029 (56%), Positives = 708/1029 (69%), Gaps = 116/1029 (11%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGR VYRYRFIV+ V +CLG G+FG++LG HVTQSGF+ D S+SV+ASV+ D Sbjct 1 MFAWWGRMVYRYRFIVVAAFVTVCLGSGLFGITLGDHVTQSGFFADNSESVKASVMADDA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATG- 119 GRDR+ H+VA+ AP GKTVDDPA+ KKV+D ++ Q+D+PD+V GWAG+LRA T Sbjct 61 LGRDRTTHVVAVIAAPEGKTVDDPAFQKKVIDHFDQLQKDNPDEVYGWAGWLRAPTTTDP 120 Query 120 ----MATADKKYTFVSIPLKGDDDDTILNNYKAIA-PDLQR--------LDGGTVKLAGL 166 M T D+K+TFVS+ LKGDDDDTILNNYKA++ PD +DG ++LAGL Sbjct 121 TVKRMVTEDRKHTFVSVSLKGDDDDTILNNYKALSNPDKDDDPAKNKFLMDGVDIQLAGL 180 Query 167 QPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRF 226 QPVA LTGTI DQ+RMEVL+LP++AVVLFFVFGGVIAAGLP+MVGGL IAGALGIMR Sbjct 181 QPVASELTGTIGKDQQRMEVLSLPVMAVVLFFVFGGVIAAGLPLMVGGLTIAGALGIMRL 240 Query 227 LAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVT 286 + +F PVH+FAQPVV+LIGLGIAIDY LFIVSRFREEIAEGYDTETAVRRTVIT+GRTV Sbjct 241 VTLFAPVHFFAQPVVTLIGLGIAIDYSLFIVSRFREEIAEGYDTETAVRRTVITSGRTVM 300 Query 287 FSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVR 346 FSA LI A+ + +L+ PQ FL+SLTYA IASV+L+AIL++TVLPACLG+LG+HVDAL ++ Sbjct 301 FSATLIAAALMPMLIVPQQFLRSLTYAGIASVLLAAILAVTVLPACLGVLGRHVDALSIK 360 Query 347 TLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVII 406 R RTK+REE+E GFWG+ V VM+RP++FA PIVI+ Sbjct 361 -----------------------RFSRTKSREELENGFWGRTVVYVMQRPLVFAVPIVIV 397 Query 407 MILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTD 466 M+LLIIP+G L LGG SEKYLPPTNSVRQAQE FD LFPG+RT +T+V + + TD Sbjct 398 MLLLIIPLGNLKLGGFSEKYLPPTNSVRQAQENFDSLFPGFRTETITIVTKGA-----TD 452 Query 467 AQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLT 526 +Q+ IR+ AM + GF+EP D MWQ R AV D SV+V+QN L++ A K+ Sbjct 453 SQLNQIRADAMKVPGFVEPGGDKTQMWQRR-QAVKTDGDTSVKVIQNALVDRNTAGAKVK 511 Query 527 ELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIK 586 +LR I PKG+T+ VGGTPALE DSI +F K+P ++V+L++ T +LMFLAFGS+VLPIK Sbjct 512 QLREIPVPKGVTMYVGGTPALEQDSIDTVFDKLPFVIVVLISVTTILMFLAFGSLVLPIK 571 Query 587 ATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLV 646 A +MSAL LGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVI LII +++GLS+DYEVFL+ Sbjct 572 AAVMSALGLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIVLIIVVIYGLSSDYEVFLM 631 Query 647 SRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAA 706 SRM+EAR +G+ST EA+R+GTA TGRIITAAALI+ VVAG F FSDLVMMKYLAFGL+AA Sbjct 632 SRMIEARHQGLSTTEAVRVGTANTGRIITAAALILIVVAGGFAFSDLVMMKYLAFGLIAA 691 Query 707 LLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPV------- 759 L+LDATVVRM L+P+VMKLLGDDCWWAP W +R+Q ++GLGE+ LPDERKRP Sbjct 692 LILDATVVRMLLIPAVMKLLGDDCWWAPAWMKRIQVKLGLGEVTLPDERKRPTGREQAIA 751 Query 760 -------SNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPAR---------SSP 803 SN R + P+ + + PR HDP+ P +P P + Sbjct 752 AASSPVGSNARTTKLPIASERTRLPSTPTPR-QHDPSAPARPTPPPPAPPTAPVNLAGND 810 Query 804 ASSPELTPALEATAAPAAPSGASTTRMQIGSSTEP--PTTRLAAAG----------RSVQ 851 + T + AP+ A TTR+ G+ P PTTR + AG R ++ Sbjct 811 SGDASATTRMAVPGKNVAPTDAPTTRVPGGNPAGPDAPTTRSSVAGTHRPDRRNADREIE 870 Query 852 SPAST--PPPTPTPPSAPSAGQ-TRAMPLAANRST-------DAAGDPAEP-TAALPIIR 900 S P P + AG T A+P++ +ST A+G P E T A+PI + Sbjct 871 SWLGELRGPKQPGAAAGTEAGDATTAIPVSKPQSTPRPAQPNRASGTPGEDATTAMPIAK 930 Query 901 SD-------------------GDDSEAATEQLNARGTSDKTRQ-------RRRGGGALSA 934 + S ATE L A G + +Q RR GG++SA Sbjct 931 PEVQRQGPPRAQRPQPEQQQPAKPSTDATEALPAPGQNRTPQQQEVDEATRRSRGGSVSA 990 Query 935 QDLLRREGR 943 QDLLRREGR Sbjct 991 QDLLRREGR 999 >gi|111022141|ref|YP_705113.1| hypothetical protein RHA1_ro05174 [Rhodococcus jostii RHA1] gi|110821671|gb|ABG96955.1| possible membrane protein [Rhodococcus jostii RHA1] Length=1004 Score = 793 bits (2049), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/758 (54%), Positives = 535/758 (71%), Gaps = 45/758 (5%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA WG VYR RF VIG+MVAL LG +GL L KH++QSG+ D GS+SV A+ L D Sbjct 1 MFASWGSVVYRARFTVIGIMVALLLGSAAYGLGLEKHLSQSGWDDPGSESVAAAKLADGT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGW-AGYLR---ASQ 116 +GRD + +VA++ AP GKT++DP + KVV+ L R +HPD++L GY + A Q Sbjct 61 FGRDTNSDVVALYTAPEGKTIEDPDFQAKVVENLERLAAEHPDKILKINGGYFKVGSAPQ 120 Query 117 ATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 A ADK++ SI + GD+D + N++ + + +DG V+LAGLQPV+ AL T Sbjct 121 LASAADADKQHAIESIAIVGDNDTEVTANFRDVKDEFY-IDGVDVQLAGLQPVSGALNDT 179 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 +A D RRME+LA+P V ++LFFVFGGV+AA LP+++GGL + GA G++R + F V+ F Sbjct 180 MAKDIRRMEILAIPAVGILLFFVFGGVVAAALPLIIGGLTVVGANGVVRLITNFTEVNSF 239 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 PVVSL+GLG+AIDYGLFIVSRFREE+AEGYDT +AVRRTV+T+GRTV FSA +IVAS Sbjct 240 VAPVVSLVGLGLAIDYGLFIVSRFREEMAEGYDTRSAVRRTVMTSGRTVVFSATMIVASL 299 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GLLLFPQGFLKS+ Y IA+V L+A+ SIT+LPA LGILGK +DAL + Sbjct 300 GGLLLFPQGFLKSVAYGAIATVGLAALTSITILPAILGILGKRIDALSL----------- 348 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 DR ++TK EE+EA WG+L VM+ P+ PIV+ ++LLI+P+ Sbjct 349 ------------DRFRQTKNTEEIEASIWGRLTRWVMRNPLKVTIPIVVGLLLLIVPLTG 396 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP +S R AQE+FD++FP RT P+ LV+ ++++ + I +A Sbjct 397 IKFGGINETYLPPDSSTRAAQEQFDEIFPNLRTEPVKLVVSDADNK-----ALGQIIKEA 451 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 G IE R GA+KD V VL+ GL++ ++ + LRA+ P G Sbjct 452 SGAPGLIE-----------RFTPEGAAKD-GVVVLKAGLVDRNESKPTIDYLRAMDSPDG 499 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 + VLVGGTPA+E DSI L +P MV+ +L T +LMFL FGS+VLPIKA LMSAL LG Sbjct 500 VQVLVGGTPAIEQDSIAALLDHLPTMVISVLVLTTLLMFLTFGSLVLPIKAALMSALGLG 559 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 ST+GILTWIF+DGH S+WLNFTP P+ +PV+ LIIA+V+GLSTDYEVFL+SRMVEAR +G Sbjct 560 STLGILTWIFIDGHGSEWLNFTPGPIMSPVLVLIIAIVYGLSTDYEVFLLSRMVEARAQG 619 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 ST E+IRIGTA TGRIITAAALI+ VV GAF FS+LVMMKY+++G++AAL++DAT++RM Sbjct 620 ASTTESIRIGTAHTGRIITAAALILIVVTGAFGFSELVMMKYISYGMIAALIIDATLIRM 679 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDE 754 FLVP+ MKLLGDDCWWAP W +R+Q + GLGE L +E Sbjct 680 FLVPATMKLLGDDCWWAPAWMKRIQEKTGLGEPILDNE 717 >gi|312141446|ref|YP_004008782.1| integral membrane protein mmpl5 [Rhodococcus equi 103S] gi|311890785|emb|CBH50104.1| putative integral membrane protein MmpL5 [Rhodococcus equi 103S] Length=894 Score = 787 bits (2033), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/951 (49%), Positives = 589/951 (62%), Gaps = 87/951 (9%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA WG VYR RF VI VMVA L G +G +G H++QSG+ D GS+SV A+ L D Sbjct 1 MFARWGDLVYRARFTVIAVMVAGLLALGAYGSGVGSHLSQSGWDDPGSESVAAAKLADGT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAG-YLR---ASQ 116 +GRD +G +VA++ AP GKTVDDPA++ +V D L R Q+HPDQV G Y + + Sbjct 61 FGRDTNGDVVAMYTAPEGKTVDDPAFAAQVSDSLQRLLQEHPDQVAKVNGSYFQLPNTPR 120 Query 117 ATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 MATAD+ + SI LKGDDD I NN++ I D +DG V+LAG+QPVA A+ T Sbjct 121 LPAMATADRTHAIASIALKGDDDTAITNNFREIK-DAFAIDGVEVQLAGMQPVASAINDT 179 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 +A D RME++A+P VAV+LFFVFGGVIAA LP++VGGL I GA GI+R + F V+ F Sbjct 180 MANDLHRMEIIAIPAVAVLLFFVFGGVIAAALPLVVGGLTILGANGIVRVITHFTDVNAF 239 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 VVSLIGLG+AIDYGLFIVSRFREE+ +GYDT TAVRR+V+TAGRTV FSA +I S Sbjct 240 VASVVSLIGLGLAIDYGLFIVSRFREELGDGYDTRTAVRRSVMTAGRTVLFSATMIAVSL 299 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GL+LFPQGFLKS+ Y IA+V+L+A S+TVLPA L ILG+ +D G++ Sbjct 300 GGLILFPQGFLKSVAYGAIATVLLAAFTSVTVLPAILSILGRRIDKFGLK---------- 349 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 R + K+ EE+E WG+L VM+ P+ PIV+ ++LLIIP+ Sbjct 350 -------------RFGQIKSTEEIENSIWGRLTRWVMRNPLKVTIPIVVGLLLLIIPMTG 396 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP N+ R AQE+FD+LFPG RT P+ LVI + Q+ I A Sbjct 397 IKFGGINEDYLPPDNTTRVAQEQFDELFPGNRTEPVKLVIDGAQG-----TQVGQILKTA 451 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 G +E + G +KD V+VL+ GL++ ++++ + LR++ P G Sbjct 452 SEAPGLVE-----------KFTITGPAKD-GVQVLKAGLVDRNNSAETIDYLRSMPVPDG 499 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 I VLVGGTPA+E DSI L +PLMV +L T +LMFLAFGS+VLPIKA LMSAL LG Sbjct 500 IQVLVGGTPAIEQDSISALLDNLPLMVASVLIVTTLLMFLAFGSIVLPIKAVLMSALGLG 559 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 ST+GILTWIF+DGH + L FTP P+T+PV+ LI+A+++GLS DYEVFL+SRMVEAR +G Sbjct 560 STLGILTWIFIDGHGADALGFTPGPITSPVLVLIVAIIYGLSIDYEVFLLSRMVEARSQG 619 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 ST EAIRIGTA TGRIITAAALI+ VV GAF FS+LVMMKY+A+G++AAL++DAT++RM Sbjct 620 ASTTEAIRIGTAHTGRIITAAALILIVVTGAFGFSELVMMKYIAYGMIAALIIDATLIRM 679 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDE-----------RKRPV-----S 760 FLVP+VMKLLGDDCWWAP W +R+Q +IGLGE L E PV + Sbjct 680 FLVPAVMKLLGDDCWWAPAWMKRIQQKIGLGEPILDSELSGDAVPDLTATDAPVPAPTEA 739 Query 761 NGRPARPPVTAGLVAARAAGDPRP-----PHDPTHPLAES----PRPARSSPASSPELTP 811 G PA P A A +P P P P A S P P R PA P++ P Sbjct 740 AGAPAIAPRGAATAVADRVPEPEPLTMPLPRVTAAPRARSVSQRPAPDRPEPAPKPDVRP 799 Query 812 ALEATAAPAAP-SGASTTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAG 870 + AP S A + ++ P T AA +VQ P P TPT SA Sbjct 800 KPDVRPRAEAPVSRADGEEVAWLAALRAPNT---AAMPAVQVPPQ-PEKTPTENSAAPRS 855 Query 871 QTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDK 921 +T A S DP P R D + +L AR D Sbjct 856 ETPA------ESGPDEADPENPG------RHRSGDKAVSVSELLARHRDDD 894 >gi|226364634|ref|YP_002782416.1| hypothetical protein ROP_52240 [Rhodococcus opacus B4] gi|226243123|dbj|BAH53471.1| hypothetical membrane protein [Rhodococcus opacus B4] Length=991 Score = 782 bits (2020), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/886 (50%), Positives = 578/886 (66%), Gaps = 64/886 (7%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA WG VYR RF VIG+MVAL LG +GL L KH++QSG+ D GS+SV A+ L D Sbjct 1 MFASWGSVVYRARFTVIGIMVALLLGSAAYGLGLEKHLSQSGWDDPGSESVAAAKLADGT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGW-AGYLR---ASQ 116 +GRD + +VA++ AP GKT++DP + KVV+ L R +HPD++L GY + A Q Sbjct 61 FGRDTNSDVVALYTAPEGKTIEDPEFQAKVVENLERLAAEHPDKILKINGGYFKVGTAPQ 120 Query 117 ATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 A ADK++ SI + GD+D + N++ + D +DG V+LAGLQPV+ AL T Sbjct 121 LASAADADKQHAIESIAIVGDNDTEVTANFRDVK-DEFYIDGVDVQLAGLQPVSGALNDT 179 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 +ATD RRME+LA+P V ++LFFVFGGV+AA LP+++GGL + GA GI+R + F V+ F Sbjct 180 MATDIRRMELLAIPAVGILLFFVFGGVVAAALPLIIGGLTVVGANGIVRLITNFTEVNSF 239 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 PVVSL+GLG+AIDYGLFIVSRFREE+AEGYDT +AVRRTV+T+GRTV FSA +IVAS Sbjct 240 VAPVVSLVGLGLAIDYGLFIVSRFREEMAEGYDTRSAVRRTVMTSGRTVVFSATMIVASL 299 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GLLLFPQGFLKS+ Y IA+V L+A+ SIT+LPA LGILGK VDAL + Sbjct 300 GGLLLFPQGFLKSVAYGAIATVGLAALTSITILPAILGILGKRVDALSL----------- 348 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 DR ++TK EE+EA WG+L VM+ P+ PIV+ ++LLI+P+ Sbjct 349 ------------DRFRQTKNTEEIEASIWGRLTRWVMRNPLKVTIPIVVGLLLLIVPLTG 396 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP +S R AQE+FD++FP RT P+ LV+ ++++ + I +A Sbjct 397 IKFGGINETYLPPDSSTRAAQEQFDEIFPNLRTEPVKLVVSDADNK-----ALGQIIKEA 451 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 G IE R GA+KD V VL+ GL++ ++ + LRA+ P G Sbjct 452 SGAPGLIE-----------RFTPEGAAKD-GVVVLKAGLVDRNESKPTIDYLRAMDKPDG 499 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 + VLVGGTPA+E DSI L +P MV+ +L T +LMFL FGS+VLPIKA LMSAL LG Sbjct 500 VQVLVGGTPAIEQDSIAALLDHLPTMVISVLFLTTLLMFLTFGSLVLPIKAALMSALGLG 559 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 ST+GILTWIF+DGH S+WLNFTP P+ +PV+ LIIA+V+GLSTDYEVFL+SRMVEAR +G Sbjct 560 STLGILTWIFIDGHGSEWLNFTPGPIMSPVLVLIIAIVYGLSTDYEVFLLSRMVEARAQG 619 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 ST E+IRIGTA TGRIITAAALI+ VV GAF FS+LVMMKY+++G++AAL++DAT++RM Sbjct 620 ASTTESIRIGTAHTGRIITAAALILIVVTGAFGFSELVMMKYISYGMIAALVIDATLIRM 679 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAA 776 FLVP+ MKLLGDDCWWAP W +R+Q + GL E L +E PA P + A Sbjct 680 FLVPATMKLLGDDCWWAPAWMKRIQEKTGLAEPILDNELM-------PADVPELTPIGAV 732 Query 777 RAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSST 836 P LA P P + P + P A AA + A R Q + Sbjct 733 ----------PPQRKLAAPPAPRKPEPLTEPIPLVTARALAAKMSEDDAQARRAQ-DEAR 781 Query 837 EPPTTRLAAAGRSVQSPASTPPPTPTP-PSAPSAGQTRAMPLAANR 881 T R A ++ PA+ P T P P P A T++ P A+R Sbjct 782 RSATGRPARPPVEIEEPAAEPQTTALPQPVPPRAAPTQSRPAPASR 827 >gi|325677137|ref|ZP_08156805.1| membrane protein MmpL [Rhodococcus equi ATCC 33707] gi|325552042|gb|EGD21736.1| membrane protein MmpL [Rhodococcus equi ATCC 33707] Length=761 Score = 773 bits (1996), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/821 (52%), Positives = 546/821 (67%), Gaps = 72/821 (8%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA WG VYR RF VI VMVA L G +G +G H++QSG+ D GS+SV A+ + D Sbjct 1 MFARWGDLVYRARFTVIAVMVAGLLALGAYGSGVGSHLSQSGWDDPGSESVAAAKVADGT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAG-YLR---ASQ 116 +GRD +G +VA++ AP GKTVDDPA++ +V D L R Q+HPDQV G Y + + Sbjct 61 FGRDTNGDVVAMYTAPEGKTVDDPAFAAQVSDSLQRLLQEHPDQVAKVNGSYFQLPNTPR 120 Query 117 ATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 MATAD+ + SI LKGDDD I NN++ I D +DG V+LAG+QPVA A+ T Sbjct 121 LPAMATADRTHAIASIALKGDDDTAITNNFREI-KDAFAIDGVEVQLAGMQPVASAINDT 179 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 +A D RME++A+P VAV+LFFVFGGVIAA LP++VGGL I GA GI+R + F V+ F Sbjct 180 MANDLHRMEIIAIPAVAVLLFFVFGGVIAAALPLVVGGLTILGANGIVRVITHFTDVNAF 239 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 VVSLIGLG+AIDYGLFIVSRFREE+ +GYDT TAVRR+V+TAGRTV FSA +I S Sbjct 240 VASVVSLIGLGLAIDYGLFIVSRFREELGDGYDTRTAVRRSVMTAGRTVLFSATMIAVSL 299 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GL+LFPQGFLKS+ Y IA+V+L+A S+TVLPA L ILG+ +D G++ Sbjct 300 GGLILFPQGFLKSVAYGAIATVLLAAFTSVTVLPAILSILGRRIDKFGLK---------- 349 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 R + K+ EE+E WG+L VM+ P+ PIV+ ++LLIIP+ Sbjct 350 -------------RFGQIKSTEEIENSIWGRLTRWVMRNPLKVTIPIVVGLLLLIIPMTG 396 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP N+ R AQE+FD+LFPG RT P+ LVI + Q+ I A Sbjct 397 IKFGGINEDYLPPDNTTRVAQEQFDELFPGNRTEPVKLVIDGAQGT-----QVGQILKTA 451 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 G +E + G +KD V+VL+ GL++ ++++ + LR++ P G Sbjct 452 SEAPGLVE-----------KFTITGPAKD-GVQVLKAGLVDRNNSAETIDYLRSMPVPDG 499 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 + VLVGGTPA+E DSI L +PLMV +L T +LMFLAFGS+VLPIKA LMSAL LG Sbjct 500 VQVLVGGTPAIEQDSISALLDNLPLMVASVLIVTTLLMFLAFGSIVLPIKAVLMSALGLG 559 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 ST+GILTWIF+DGH + L FTP P+T+PV+ LI+A+++GLS DYEVFL+SRMVEAR +G Sbjct 560 STLGILTWIFIDGHGADALGFTPGPITSPVLVLIVAIIYGLSIDYEVFLLSRMVEARSQG 619 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 ST EAIRIGTA TGRIITAAALI+ VV GAF FS+LVMMKY+A+G++AAL++DAT++RM Sbjct 620 ASTTEAIRIGTAHTGRIITAAALILIVVTGAFGFSELVMMKYIAYGMIAALIIDATLIRM 679 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAA 776 FLVP+VMKLLGDDCWWAP W +R+Q +IGLGE L E Sbjct 680 FLVPAVMKLLGDDCWWAPAWMKRIQQKIGLGEPILDSEL--------------------- 718 Query 777 RAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATA 817 +GD P T ++P PA + A +P + P ATA Sbjct 719 --SGDDVPDLTAT----DAPVPAPTEAAGAPAIAPRGAATA 753 >gi|226304573|ref|YP_002764531.1| hypothetical protein RER_10840 [Rhodococcus erythropolis PR4] gi|226183688|dbj|BAH31792.1| conserved hypothetical membrane protein [Rhodococcus erythropolis PR4] Length=968 Score = 772 bits (1993), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/877 (51%), Positives = 567/877 (65%), Gaps = 66/877 (7%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA WG VYR RF VI VMVA LG +GLSL H++QSG+ D GS+SV+A+ L D Sbjct 1 MFASWGSIVYRARFTVIAVMVAGLLGLAAYGLSLQDHLSQSGWDDPGSESVEAAKLADGT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAG-YLRASQA-- 117 +GR +G ++A++ AP GKTVDDP + KV+D L R D+PDQ++ G Y + Sbjct 61 FGRSTTGDVLALYTAPEGKTVDDPEFQAKVIDNLQRLVADNPDQIMKINGSYFKVDNGLS 120 Query 118 -TGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 +A K++ SI + GD+D + NN++ + +DG V+LAGLQPVA +L T Sbjct 121 VAALADKTKQHAVTSIAIAGDNDTAVSNNFRDVESQFY-IDGVDVQLAGLQPVANSLNDT 179 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 +A D +RME+LA+P V V+LFFVFGGV+AA LP++VGGL + GA GI+R + F V+ F Sbjct 180 MANDIKRMEMLAIPAVGVLLFFVFGGVVAAALPLIVGGLTVIGANGIIRLITNFTEVNAF 239 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 PVVSL+GLG+AIDYGLFIVSRFREEIAEGYDT TAVRRTV+TAGRTV FSA ++ S Sbjct 240 VAPVVSLVGLGLAIDYGLFIVSRFREEIAEGYDTPTAVRRTVMTAGRTVMFSATMVAVSL 299 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GLLLFPQGFLKS+ Y IA+VML+AI SIT+LPA LGILGK +DAL + Sbjct 300 GGLLLFPQGFLKSVAYGAIAAVMLAAISSITILPAILGILGKRIDALTFK---------- 349 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 +L++TKT EE+E GFWGKL VM+ P+ A PIV ++L+IIP+ Sbjct 350 -------------KLRQTKTNEEIENGFWGKLTRWVMQHPLKVAVPIVAALLLMIIPLTG 396 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP + R AQ +FD+LFPG RT P+ LVI+ +++ + I A Sbjct 397 IKFGGINETYLPPDSPTRVAQAQFDELFPGNRTEPVRLVIEGADN-----TTLGQISKTA 451 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 A G +E + A+KD V VL+ GL +A + LR+ P+G Sbjct 452 NAAPGLVE-----------KFTPEVATKD-GVNVLKAGLTERNEARPTIDYLRSADWPEG 499 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 TVLVGGTPA+E DS+ L ++PLMVV ++ T +LMFL FGS+VLPIKA LMSAL LG Sbjct 500 TTVLVGGTPAIEQDSVDALLDRLPLMVVSVILLTTLLMFLTFGSLVLPIKAALMSALGLG 559 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 ST+GILTWIF+DGH S LNFTP P+ +PV+ LIIA+V+GLSTDYEVFL+SRMVEAR +G Sbjct 560 STLGILTWIFIDGHGSGLLNFTPGPIMSPVLVLIIAIVYGLSTDYEVFLLSRMVEARAQG 619 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 ST E+IRIGTA TGRIITAAALI+ VV GAF SDLVMMKY+++G+++AL++DAT++RM Sbjct 620 ASTTESIRIGTAHTGRIITAAALILIVVTGAFGLSDLVMMKYISYGMISALIIDATLIRM 679 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAA 776 FLVP+ MKLLGDDCWWAP W +R+Q +IGLGE L +E A P A + A Sbjct 680 FLVPATMKLLGDDCWWAPAWMKRIQQKIGLGEPILDNELVL-------ANVPQIAPVGAI 732 Query 777 RAAGDPRPPHDPTHPLAESPR-------PARSSPASSP----ELTPALEATAAPAAPSGA 825 G PR + + P P + P E+T T APAA A Sbjct 733 AGPGQPRKIEAASRVMPPPAPAAQPESGPRVPDPLTEPIPLSEMTIKAPNTDAPAAEKPA 792 Query 826 STTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPT 862 R+ IGS+ P + A V +P+ P P T Sbjct 793 PRRRLDIGSAASAPQNLIEA---PVPNPSYRPQPNTT 826 >gi|229494459|ref|ZP_04388222.1| putative membrane protein [Rhodococcus erythropolis SK121] gi|229318821|gb|EEN84679.1| putative membrane protein [Rhodococcus erythropolis SK121] Length=979 Score = 771 bits (1991), Expect = 0.0, Method: Compositional matrix adjust. Identities = 441/894 (50%), Positives = 569/894 (64%), Gaps = 74/894 (8%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA WG VYR RF VI VMVA LG +GLSL H++QSG+ D GS+SV+A+ L D Sbjct 1 MFASWGSIVYRARFTVIAVMVAGLLGLAAYGLSLQDHLSQSGWDDPGSESVEAAKLADGT 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAG-YLRASQA-- 117 +GR +G ++A++ AP GKTVDDP + KV+D L R D+PDQ++ G Y + Sbjct 61 FGRSTTGDVLALYTAPEGKTVDDPEFQAKVIDNLQRLVADNPDQIMKINGSYFKVDNGLS 120 Query 118 -TGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 +A K++ SI + GD+D + NN++ + +DG V+LAGLQPVA +L T Sbjct 121 VAALADKTKQHAVTSIAIAGDNDTAVSNNFRDVESQFY-IDGVDVQLAGLQPVANSLNDT 179 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 +A D +RME+LA+P V V+LFFVFGGV+AA LP++VGGL + GA GI+R + F V+ F Sbjct 180 MANDIKRMEMLAIPAVGVLLFFVFGGVVAAALPLIVGGLTVIGANGIIRLITNFTEVNAF 239 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 PVVSL+GLG+AIDYGLFIVSRFREEIAEGYDT TAVRRTV+TAGRTV FSA ++ S Sbjct 240 VAPVVSLVGLGLAIDYGLFIVSRFREEIAEGYDTPTAVRRTVMTAGRTVMFSATMVAVSL 299 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GLLLFPQGFLKS+ Y IA+VML+AI SIT+LPA LGILGK +DAL + Sbjct 300 GGLLLFPQGFLKSVAYGAIAAVMLAAISSITILPAILGILGKRIDALTFK---------- 349 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 +L++TKT EE+E GFWGKL VM+ P+ A PIV ++L+IIP+ Sbjct 350 -------------KLRQTKTNEEIENGFWGKLTRWVMQHPLKVAVPIVAALLLMIIPLTG 396 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP + R AQ +FD+LFPG RT P+ LVI+ +++ + I A Sbjct 397 IKFGGINETYLPPDSPTRVAQAQFDELFPGNRTEPVRLVIEGADN-----TTLGQISKTA 451 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 A G +E + A+KD V VL+ GL +A + LR+ P+G Sbjct 452 NAAPGLVE-----------KFTPEVATKD-GVNVLKAGLTERNEARPTIDYLRSADWPEG 499 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 TVLVGGTPA+E DS+ L ++PLMVV ++ T +LMFL FGS+VLPIKA LMSAL LG Sbjct 500 TTVLVGGTPAIEQDSVDALLDRLPLMVVSVILLTTLLMFLTFGSLVLPIKAALMSALGLG 559 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 ST+GILTWIF+DGH S LNFTP P+ +PV+ LIIA+V+GLSTDYEVFL+SRMVEAR +G Sbjct 560 STLGILTWIFIDGHGSGLLNFTPGPIMSPVLVLIIAIVYGLSTDYEVFLLSRMVEARAQG 619 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 ST E+IRIGTA TGRIITAAALI+ VV GAF SDLVMMKY+++G+++AL++DAT++RM Sbjct 620 ASTTESIRIGTAHTGRIITAAALILIVVTGAFGLSDLVMMKYISYGMISALIIDATLIRM 679 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAA 776 FLVP+ MKLLGDDCWWAP W +R+Q +IGLGE L +E A P A + A Sbjct 680 FLVPATMKLLGDDCWWAPAWMKRIQQKIGLGEPILDNELVL-------ANVPQIAPVGAI 732 Query 777 RAAGDPRPPHDPTHPLAESPR-------PARSSPASSP----ELTPALEATAAPAAPSGA 825 G PR + + P P + P E+ T APAA A Sbjct 733 AGPGQPRKIEAASRVMPPPAPAAQPESGPRVPDPLTEPIPLSEMAIKAPNTEAPAAEKPA 792 Query 826 STTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAA 879 R+ IGS+ P + A P P P+ P+A R P A Sbjct 793 PRRRLDIGSAASAPQNLIEA-----------PVPNPSYRPQPNASDKRRNPTPA 835 >gi|119854939|ref|YP_935544.1| MmpL family membrane protein [Mycobacterium sp. KMS] gi|119697657|gb|ABL94729.1| membrane protein, MmpL family [Mycobacterium sp. KMS] Length=632 Score = 744 bits (1922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/592 (66%), Positives = 470/592 (80%), Gaps = 14/592 (2%) Query 9 VYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGH 68 VYRYRF V+ M A CLG GVFG+SLG+HVTQSGF+DDGS+S QAS L D YGRD SGH Sbjct 2 VYRYRFFVVVAMTAACLGAGVFGISLGEHVTQSGFFDDGSESAQASRLADTAYGRDTSGH 61 Query 69 IVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQA-TGMATADKKY 127 I+AI+ AP G TVDDPA V L+ Q HPD++L GY + + MA A +++ Sbjct 62 IIAIYTAPEGTTVDDPAVRDHVNHSLDTAIQKHPDEILRAVGYFTNPEILSTMADASRQH 121 Query 128 TFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGT-VKLAGLQPVAEALTGTIATDQRRMEV 186 F+SI L+GDDDDTILNNYK +A L +DGG V+LAGLQP+A LT TI TDQ+RME+ Sbjct 122 AFMSIQLRGDDDDTILNNYKKVANSLG-VDGGVEVQLAGLQPLANELTSTIGTDQKRMEL 180 Query 187 LALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPVVSLIGL 246 LALPLVA+VLFFVFGGV+AA LPV+VGGL IAGALGIMR ++ PVH AQPVVSLIGL Sbjct 181 LALPLVAIVLFFVFGGVVAATLPVLVGGLSIAGALGIMRLISEITPVHALAQPVVSLIGL 240 Query 247 GIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGF 306 GIAIDYGLF+VSRFREE+AEGYDT TAVRRTV TAGRTV FSA+LIVAS+ G+LLFPQGF Sbjct 241 GIAIDYGLFVVSRFREELAEGYDTPTAVRRTVTTAGRTVMFSAILIVASSAGVLLFPQGF 300 Query 307 LKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLN- 365 LK+LTYA IASVML+A+LSITVLPA LGILG++VDALGVRTL R+PF+ N +LN Sbjct 301 LKALTYAIIASVMLAAVLSITVLPAILGILGRNVDALGVRTLLRIPFVRN----TVWLNG 356 Query 366 ---WLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGI 422 W ADR QRTKTR EVE GFWG+LV RVMKRP+++A PI++ M+LLI+P+GK++LGGI Sbjct 357 IALWFADRTQRTKTRREVENGFWGRLVTRVMKRPLIYAIPIIVGMVLLILPLGKITLGGI 416 Query 423 SEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGF 482 SEKYLPPTNSVRQAQE+FDK FPG+RT PLTLVI ++ QPVTD Q+ADIR++AMAI GF Sbjct 417 SEKYLPPTNSVRQAQEQFDKTFPGFRTEPLTLVITHNDGQPVTDEQVADIRNRAMAIPGF 476 Query 483 IEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVG 542 PD PA+MW ER+ GA++ P VRV+QNGLI+ A+ ++ LR + P G+T+ VG Sbjct 477 TVPDAGPASMWAERSRLDGATQQPDVRVIQNGLIDRNSAAGRIDALRDLPSPDGLTIRVG 536 Query 543 GTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVL---PIKATLMS 591 GTPALE DSI GLF K+PLM+++L+TTT +LM LAFGS+VL P+K T +S Sbjct 537 GTPALEQDSIQGLFDKLPLMLLVLITTTTLLMLLAFGSLVLTAYPLKWTCVS 588 Score = 59.7 bits (143), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 59/199 (30%), Positives = 97/199 (49%), Gaps = 20/199 (10%) Query 536 GITVLVGGTPAL--ELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSAL 593 G+ V + G L EL S G K M ++ L +++F FG VV L+ L Sbjct 152 GVEVQLAGLQPLANELTSTIGTDQKR--MELLALPLVAIVLFFVFGGVVAATLPVLVGGL 209 Query 594 TLGSTMGILTWIFVDGHFSKWLNFTPT-PLTAPVIGLIIALVFGLSTDYEVFLVSRMVEA 652 ++ +GI+ I TP L PV+ LI G++ DY +F+VSR E Sbjct 210 SIAGALGIMRLIS---------EITPVHALAQPVVSLI---GLGIAIDYGLFVVSRFREE 257 Query 653 RERGMSTQEAIRIGTAATGR-IITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDA 711 G T A+R GR ++ +A LIVA AG +F +K L + ++A+++L A Sbjct 258 LAEGYDTPTAVRRTVTTAGRTVMFSAILIVASSAGVLLFPQ-GFLKALTYAIIASVML-A 315 Query 712 TVVRMFLVPSVMKLLGDDC 730 V+ + ++P+++ +LG + Sbjct 316 AVLSITVLPAILGILGRNV 334 >gi|262204299|ref|YP_003275507.1| drug exporter of the RND superfamily-like protein [Gordonia bronchialis DSM 43247] gi|262087646|gb|ACY23614.1| drug exporter of the RND superfamily-like protein [Gordonia bronchialis DSM 43247] Length=1095 Score = 740 bits (1910), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/929 (50%), Positives = 590/929 (64%), Gaps = 45/929 (4%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +F G VYR RF VI VM+AL G G++GL LGKH++QSG++D S+SV+ S D Sbjct 1 MFGAIGTFVYRMRFAVIAVMIALMAGLGLYGLDLGKHLSQSGWFDPTSESVRGSQYADAA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLG---------WAGY 111 GRD I+ + PAG TVDDPA+ KV ++ HPD V + Sbjct 61 LGRDHRSDIILLVTPPAGTTVDDPAFGAKVETFVDDLIAAHPDIVNRQDPGVIDPFFKQS 120 Query 112 LRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLD------GGTVKLAG 165 ++++ TADKK+ F+SI + G+DD T+LNNYK I P +D G T +LAG Sbjct 121 VQSAVQERTFTADKKHAFISIGVAGNDDTTVLNNYKTIEPFFHDIDDRFGLEGTTFELAG 180 Query 166 LQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMR 225 LQPVA ++ + D R EV+ALP+VA++LFF+FGGV+AA LPV++GGL IAG+LGIM+ Sbjct 181 LQPVAGSMADGMDKDIHRAEVIALPIVAIMLFFIFGGVVAACLPVLIGGLTIAGSLGIMK 240 Query 226 FLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTV 285 LA+ ++ FAQ VV+LIGLGIAIDYGLFIVSRFREE+ EGY T+ AVRRTV+TAG+TV Sbjct 241 ILALTTELNIFAQSVVTLIGLGIAIDYGLFIVSRFREELGEGYSTKAAVRRTVMTAGQTV 300 Query 286 TFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGV 345 FSA +IVA+ LL+ PQGFLKS+ Y IASV L+AILSITVLPA LGILG +DAL + Sbjct 301 VFSATIIVAALACLLIMPQGFLKSVAYGAIASVTLAAILSITVLPAILGILGPRIDALSI 360 Query 346 RTL--FRVPFLANWKISAAYLNWLADRLQ-RTKTREEVEAGFWGKLVNRVMKRPVLFAAP 402 TL + V L + A + L R R K+R+E+E GFWGKL VMK PV A P Sbjct 361 HTLMSWTVIPLVRKTLGAQRADALDARFTGRIKSRQEIENGFWGKLSGWVMKHPVATAVP 420 Query 403 IVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQ 462 V+++++LIIP G + GGISEKYLPP N R AQE FDK FP RT + LV+ + Sbjct 421 TVLLLLVLIIPFGGIQFGGISEKYLPPDNPNRVAQENFDKYFPTERTEEIKLVVVYDPNT 480 Query 463 PVTDAQIADIRSKAMAIGGFIEP-DNDPANMWQERAYAVGASKDPSVRVLQNGLINPADA 521 P D ++ I +A I GF +P P + Q Y + + + +GL + A Sbjct 481 PDYDYKLQAIADQANKIPGFTKPFSTSPNDGAQSGQYPNSGAW---IFQMSSGLQDRNTA 537 Query 522 SKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSV 581 ++ + +LRAI G+ + V GTPAL DSI L +++PLM V+L+ T LMFLAFGS+ Sbjct 538 AEAIKDLRAINT-GGLQMYVAGTPALTQDSIDALMSRLPLMAVLLVLVTGFLMFLAFGSI 596 Query 582 VLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDY 641 VLPIKA LMSAL LG+T+GILTWIFVDGH ++ NFTP PL A V+ LIIA+VFGLSTDY Sbjct 597 VLPIKAALMSALGLGATLGILTWIFVDGHGAELANFTPGPLFAAVLVLIIAIVFGLSTDY 656 Query 642 EVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAF 701 E+FL+SRMVEAR++G ST EAIR+GTA TGRIITAAA I+ VV GAF S++VMMKY+A+ Sbjct 657 EIFLLSRMVEARQKGASTTEAIRVGTAHTGRIITAAAAILVVVTGAFGMSEIVMMKYIAY 716 Query 702 GLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSN 761 G++AAL+LDATV+RM LVPSVMKLLGDDCWWAPRW R +Q +IGLGE L DE + + Sbjct 717 GMIAALILDATVIRMLLVPSVMKLLGDDCWWAPRWMRVMQQKIGLGETVLDDEPDE-LRD 775 Query 762 GRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPAR-SSPASSPELTPALEATAAPA 820 A ++AG + A A PT +A PR AR +S PE T A A Sbjct 776 RSAAAKTMSAGTLVAEA---------PTSVMAR-PRVARPASMGPPPERTAPARRAADRA 825 Query 821 APSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRA---MPL 877 +T + + T PP + A R + P P+ P AG T A P+ Sbjct 826 RTPEPTTVATERPTRTRPPAETVPPAARPARGARVGPSAPPSGPQPVGAGATSAPGGPPV 885 Query 878 AANRSTDAAGDPAEPTAALPIIRSDGDDS 906 +R T P AA P RS+G D+ Sbjct 886 TGDRPT-----PFRRPAARP--RSEGPDT 907 >gi|326383554|ref|ZP_08205240.1| drug exporter of the RND superfamily-like protein [Gordonia neofelifaecis NRRL B-59395] gi|326197638|gb|EGD54826.1| drug exporter of the RND superfamily-like protein [Gordonia neofelifaecis NRRL B-59395] Length=1049 Score = 727 bits (1876), Expect = 0.0, Method: Compositional matrix adjust. Identities = 398/791 (51%), Positives = 525/791 (67%), Gaps = 63/791 (7%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +F G VYR R+ VI V+VAL G G++G++L ++++QSG++D S+S SV+ D Sbjct 1 MFGSIGSFVYRMRYTVIAVLVALMGGLGLYGINLSQYLSQSGWFDPHSESAVGSVIADTA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVL-----GWAGYLR-- 113 GRD ++ + P G VDDPA+ K+ + +N + +PD V G AG + Sbjct 61 LGRDHKSDVILLITPPEGTKVDDPAFGAKIENIVNNLVKQYPDIVSRDSSDGHAGLIDPF 120 Query 114 ------------ASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDL----QRLD 157 + + M T D+K+ F+SI + GDDD TILNNYK I P +R D Sbjct 121 EPADAGAGQTAAEMKQSRMWTPDRKHAFISIGVAGDDDTTILNNYKTIEPFFDGLAERYD 180 Query 158 --GGTVKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGL 215 G +LAGLQP+A A++ + D R EV+ALP+VA++L FVFGGV+AA LPV +GG+ Sbjct 181 LPGTQFQLAGLQPIAAAMSKGMEDDISRAEVIALPVVALMLLFVFGGVVAAVLPVFIGGI 240 Query 216 CIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVR 275 IAG+LGIM+ LA ++ FAQ VV+LIGLGIAIDYGLFIVSRFREE+AEGY + AVR Sbjct 241 TIAGSLGIMKILAQITELNIFAQSVVTLIGLGIAIDYGLFIVSRFREELAEGYTVKAAVR 300 Query 276 RTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGI 335 RTV+TAG+TV FSA +IVA+ LL+FPQ FLKS+ Y IASV L+A+LSITVLPA L I Sbjct 301 RTVMTAGQTVVFSATIIVAALACLLMFPQAFLKSVAYGAIASVGLAAVLSITVLPAILAI 360 Query 336 LGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKR 395 LG +DAL + PFL R+KTREEVE GFWG+L VM+ Sbjct 361 LGTRIDALSL------PFL-----------------NRSKTREEVEEGFWGRLAGWVMQN 397 Query 396 PVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLV 455 PV A P V++++ LIIP G + GG++E YLPP N+ R AQE+FDK FP RT L L+ Sbjct 398 PVKTAVPTVLLLLALIIPFGNIQFGGMTEAYLPPDNANRIAQEDFDKYFPTERTEDLKLI 457 Query 456 IQTSNHQPVTDAQIADIRSKAMAIGGFIEPDNDPAN------MWQERAYAVGASKDPSVR 509 + + +I I +A I GF + + A+ ++ + +G ++ Sbjct 458 VTYDQNTEDAAGKIQRIADEANQIPGFTKQFSPTADGGALEGIYGDEETGLGVTQ----- 512 Query 510 VLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTT 569 + GL++ A + + +LR I +G+TV V GTP L DSI L +P M ++L+ Sbjct 513 -MSAGLVDRNTAPEAIKKLREIDD-QGMTVYVAGTPTLTQDSIDSLIKLLPWMAILLVLV 570 Query 570 TIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGL 629 T +LMFLAFGSV+LPIKA LM+AL LG+T+GILTWIF+DGH S NFTP PL APV+ L Sbjct 571 TGLLMFLAFGSVILPIKAALMTALGLGATLGILTWIFIDGHGSSIANFTPGPLFAPVLVL 630 Query 630 IIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFV 689 IIA+++GLSTDYE+FL+SRMVEAR++G ST EAIR GTA TGRIITAAA I+ VV GAF Sbjct 631 IIAIIYGLSTDYEIFLLSRMVEARQQGASTTEAIRTGTAHTGRIITAAAAILVVVTGAFG 690 Query 690 FSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEI 749 SD+VMMKY+A+G++AAL+LDATV+RM LVPS+MKLLGDDCWW+PRW +RLQ +IGLGE Sbjct 691 LSDIVMMKYIAYGMIAALILDATVIRMLLVPSIMKLLGDDCWWSPRWMQRLQQKIGLGEA 750 Query 750 HLPDE--RKRP 758 L D+ +KRP Sbjct 751 ILEDDPSQKRP 761 >gi|54027460|ref|YP_121702.1| hypothetical protein nfa54860 [Nocardia farcinica IFM 10152] gi|54018968|dbj|BAD60338.1| putative membrane protein [Nocardia farcinica IFM 10152] Length=1126 Score = 723 bits (1866), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/760 (52%), Positives = 518/760 (69%), Gaps = 44/760 (5%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +F WG VYR+RF VIG++ A L G +G L H++ SG+ D S+S QA+ + D+ Sbjct 1 MFTRWGELVYRFRFAVIGIVAAALLALGGYGFGLENHLSSSGWDDPTSESAQAARIADEA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAG-YLRASQATG 119 +GRD + ++ ++ AP GKT+DDP + K+VD LNR ++HPD++ G Y + G Sbjct 61 FGRDHTSDVIVLYTAPEGKTIDDPEFRDKIVDSLNRLPREHPDEIDKVNGAYWQTETGPG 120 Query 120 M----ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 + + DKKYTF SI + GD+D ++ NY+ + D+ + G V++ GLQ VA L Sbjct 121 VPLTFGSKDKKYTFASIAIVGDNDTDMVRNYRKVK-DVFYIPGVDVQVTGLQAVAGTLND 179 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 T+A+DQ+RME+LA+P VAV+LFF+FGG++AAGLP++VGGL + GA GI+ L F V+ Sbjct 180 TMASDQKRMELLAIPAVAVLLFFIFGGLVAAGLPLVVGGLTVIGANGIIMALTKFTEVNS 239 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 F VVS+IGLG+AIDYGLFIVSRFREE+AEGYDT AVRR+V+TAGRTV FSA +IVAS Sbjct 240 FVGGVVSMIGLGLAIDYGLFIVSRFREELAEGYDTPAAVRRSVMTAGRTVVFSATMIVAS 299 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 G+LLFPQGFLKS+ Y TIA+V L+A+ +IT+LPA LG+LG VD LG++ Sbjct 300 LGGMLLFPQGFLKSVAYGTIATVTLAALTAITILPAMLGVLGPRVDMLGLK--------- 350 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 R ++TKT EEVE GFWGK VM+ P+ A PI I+++LLIIPV Sbjct 351 --------------RFRKTKTAEEVENGFWGKTTQWVMRHPLKIAVPICIVLLLLIIPVK 396 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 L+ GGI+E+YLPP N R A E F ++FP +T+P+ LV+ + + A + + + Sbjct 397 NLAFGGINERYLPPDNKTRVALENFYEVFPLKKTDPVQLVMVSED-----SAAVGAVWKQ 451 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 A G + P+ ++ P V L + +A+ + LR++ P Sbjct 452 ASEAPGLVGSFEVPSR----------STTQPDVYRTSATLEDSENANPTIDYLRSMDVPD 501 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 + + VGG P ++ DSI L +MPLM+ ++L T +LMFL FGS+VLPIKA LMSAL L Sbjct 502 SVQLYVGGQPTIQKDSIDALLERMPLMIALVLFVTTLLMFLTFGSLVLPIKAALMSALGL 561 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 GST+GILTWIFVDGH S LNFTP P+ +PV+ LIIA+++GLSTDYEVFL+SRMVEAR Sbjct 562 GSTLGILTWIFVDGHGSGLLNFTPQPIMSPVLVLIIAVIYGLSTDYEVFLLSRMVEARSM 621 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 G ST EA+R GTA TGRIITAAALI+ VV GAF FSDLVMM+Y+A+GL+AAL +DAT++R Sbjct 622 GASTTEAVRAGTAHTGRIITAAALILLVVVGAFAFSDLVMMQYIAYGLIAALFIDATILR 681 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDER 755 M LVP+ MKLLGDDCWWAP W +R+Q RIGLGE L DER Sbjct 682 MLLVPATMKLLGDDCWWAPAWMKRIQERIGLGEPILDDER 721 >gi|343924436|ref|ZP_08763985.1| hypothetical protein GOALK_016_00340 [Gordonia alkanivorans NBRC 16433] gi|343765580|dbj|GAA10911.1| hypothetical protein GOALK_016_00340 [Gordonia alkanivorans NBRC 16433] Length=1094 Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/830 (51%), Positives = 554/830 (67%), Gaps = 46/830 (5%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +F G VYR RF+VI VM+AL G G++GL L KH++QSG++D S+S + D+ Sbjct 1 MFRVIGTFVYRMRFLVIAVMIALMAGLGLYGLDLSKHLSQSGWFDPTSESDLGARYADKA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAG-------YLR 113 GRD + ++ + P G TVDDP + KKV + HPD ++G A ++ Sbjct 61 LGRDHTSDVILLVTPPEGTTVDDPTFGKKVETFVEDLIATHPD-IVGRADPGLYDPFLVQ 119 Query 114 ASQAT---GMATADKKYTFVSIPLKGDDDDTILNNYKAIAP---DL-QRLD--GGTVKLA 164 +Q+ + T DK+ F+SI + G+DD T+L NY I P D+ +R D G T +LA Sbjct 120 PAQSAVQERLFTPDKRQAFISIGVAGNDDTTVLANYNTIEPFFDDIAERFDIPGATFELA 179 Query 165 GLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIM 224 GLQPV+ ++ + D +R EV+ALP+VA++LFFVFGGV+AA LPV++GGL IAG+LGIM Sbjct 180 GLQPVSGSMADGMDKDIKRAEVIALPVVALMLFFVFGGVVAACLPVLIGGLTIAGSLGIM 239 Query 225 RFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRT 284 + LA+ ++ FAQ VV+LIGLGIAIDYGLFIVSRFREE+ EGY T+ AVRRTV+TAG+T Sbjct 240 KILALTTELNIFAQSVVTLIGLGIAIDYGLFIVSRFREELGEGYSTKAAVRRTVMTAGQT 299 Query 285 VTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALG 344 V FSA +IVA+ LL+ PQGFLKS+ Y IASV L+AILSITVLPA LGILG V+ L Sbjct 300 VVFSATIIVAALACLLIMPQGFLKSVAYGAIASVSLAAILSITVLPAILGILGPRVNMLS 359 Query 345 VRTLFR---VPFLANWKISAAYLNWLADRLQ-RTKTREEVEAGFWGKLVNRVMKRPVLFA 400 + ++ + +P + + + L +R R KT +EVE GFWG+L VMK P+ A Sbjct 360 IGSILKYTAIPLVRRFSTEERAVA-LENRFSGRMKTSQEVENGFWGRLATWVMKNPLKTA 418 Query 401 APIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSN 460 P V++++ L +P G + GGISEK+LPP NS R AQE+FD+ FP RT + LVI Sbjct 419 IPTVLLLLALTVPFGSIQFGGISEKFLPPDNSARVAQEKFDEYFPSERTEAVKLVIVYDE 478 Query 461 HQPVTDAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQ--NGLINP 518 ++ I +A + GF +DP + + A + P+V V Q GL++ Sbjct 479 TNQEDQNKLEAIARQADQVPGFTNKFSDPD---KAGFGSYDAERYPNVGVYQVSAGLVDR 535 Query 519 ADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAF 578 A+K + +LRAI +G+T+ V GTPAL DSI L ++PLM ++L+ T +LMFL F Sbjct 536 TKAAKAIDQLRAIDT-QGLTMYVTGTPALTQDSIDALMNRLPLMAIMLVLITGLLMFLQF 594 Query 579 GSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLS 638 GS+VLPIKA LM+AL LG+T+GILTWIFVDGH + NFTP PL A ++ LIIA++FGLS Sbjct 595 GSLVLPIKAALMTALGLGATLGILTWIFVDGHGAGLANFTPGPLFAAILVLIIAIIFGLS 654 Query 639 TDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKY 698 TDYEVFL+SRMVEAR+RG ST E+IR G A TG IITAAA I+ VV GAF SD+VMMKY Sbjct 655 TDYEVFLLSRMVEARQRGASTTESIRSGIAHTGGIITAAAAILVVVTGAFSLSDIVMMKY 714 Query 699 LAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHL---PDER 755 +A+G++AAL+LDATV+RM LVPSVMKLLGDDCWWAPRW + +Q +IGLGE L PDE+ Sbjct 715 IAYGMIAALILDATVIRMLLVPSVMKLLGDDCWWAPRWMQTVQRKIGLGEAVLEDEPDEQ 774 Query 756 KRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAES-PRPARSSPA 804 + + R AR ++AG + A A PT +A + PR A + PA Sbjct 775 R----DSRAAR-KMSAGTLVAEA---------PTSVMAAARPRTAPTGPA 810 >gi|333921790|ref|YP_004495371.1| hypothetical protein AS9A_4137 [Amycolicicoccus subflavus DQS3-9A1] gi|333484011|gb|AEF42571.1| putative membrane protein, MmpL [Amycolicicoccus subflavus DQS3-9A1] Length=740 Score = 699 bits (1804), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/764 (50%), Positives = 509/764 (67%), Gaps = 44/764 (5%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FA GR VYR RF V+ ++VA+ G FGL LG ++QSG+ D GS+SV A + Sbjct 1 MFATLGRFVYRARFTVLALLVAILAAAGAFGLGLGDRLSQSGWDDPGSESVAAERIVKDA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM 120 +GRD +G +V +F AP G TVDDP ++ + L + + D+P +V Y + + Sbjct 61 FGRDNAGDVVVLFTAPDGFTVDDPEFASEARQLLTQIRDDNPSEVDFVRSYWDSDALHML 120 Query 121 ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD 180 AT D+++ SI L G++D +L N++ I D +++LAGLQPVA AL+ + D Sbjct 121 ATPDRQHAIASIGLLGENDTEVLANFQTIKSQFDANDS-SLQLAGLQPVANALSQGMEDD 179 Query 181 QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV 240 +RME++ALP VAV+LFF+F GV+AA LPV++G L + GA G+ R L V+ FAQ V Sbjct 180 IKRMELIALPAVAVLLFFIFRGVVAAALPVIIGVLTVGGAWGVTRLLTGVVEVNVFAQSV 239 Query 241 VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL 300 +SLIGLG+AIDYGLF+VSRFREE+AEGYD AVRRTV TAGRTV FSA +I S GLL Sbjct 240 ISLIGLGLAIDYGLFVVSRFREELAEGYDVPDAVRRTVATAGRTVVFSATIIAISLGGLL 299 Query 301 LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS 360 +FPQGFLKS+ Y IA+V ++A+L++TVLPA L ILG+ VDALG Sbjct 300 VFPQGFLKSVAYGAIAAVSIAALLAVTVLPALLSILGRKVDALGFA-------------- 345 Query 361 AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG 420 +L+ TK E++ FWG++ +KRP+ A P+ I ++LL+IP G + G Sbjct 346 ---------KLRPTKPAAEMQHTFWGRIAGWSIKRPLRVAVPVTIGLLLLVIPFGNIQFG 396 Query 421 GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG 480 G+SE YLPP N R AQ++FD+LFP +RT P+ +VI + D+ +A + Sbjct 397 GMSENYLPPDNETRIAQQQFDELFPTFRTKPIKVVITGDI------SATGDVLRQANEVP 450 Query 481 GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL 540 GF A+ + S+ +V VL GL++ A A + LRAI P G VL Sbjct 451 GF------------TGAFEL-ESRAQNVVVLSAGLVDEATAGDAIGGLRAIDVPDGTEVL 497 Query 541 VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG 600 VGG PA+E DSI + MPLM V+++ T +LMFLAFGS+ LPIKA +M+AL+LGST+G Sbjct 498 VGGGPAIERDSIDAMVTMMPLMAVVVVLITTLLMFLAFGSLTLPIKAVVMTALSLGSTLG 557 Query 601 ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ 660 ILTWIF+DGH + LNFTP PL A V+ LI+A+++GLSTDYE+FLVSRMVEAR +G ST Sbjct 558 ILTWIFIDGHGASLLNFTPGPLMAAVVVLIVAIIYGLSTDYEIFLVSRMVEARAKGASTS 617 Query 661 EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP 720 EAIR+GTA TG IITAAALI+ VV GAF FS++ MMKY+AFG++AAL++DATV+RM LVP Sbjct 618 EAIRMGTAQTGHIITAAALILIVVTGAFGFSEIAMMKYIAFGMIAALIIDATVIRMLLVP 677 Query 721 SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRP 764 SVM+LLG+DCWWAP W +R+Q +IGL E L DE RP S G P Sbjct 678 SVMRLLGEDCWWAPEWMKRIQRKIGLQEHELEDEL-RPGSTGAP 720 >gi|317509188|ref|ZP_07966812.1| hypothetical protein HMPREF9336_03184 [Segniliparus rugosus ATCC BAA-974] gi|316252545|gb|EFV11991.1| hypothetical protein HMPREF9336_03184 [Segniliparus rugosus ATCC BAA-974] Length=1053 Score = 676 bits (1743), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/786 (50%), Positives = 518/786 (66%), Gaps = 60/786 (7%) Query 6 GRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRD- 64 G V+R R+ VI VM A+ + G++G+ LG H+TQ G+YDD S+S +AS L D+ +G+D Sbjct 6 GAFVHRARYPVIAVMAAIFVALGIYGIDLGDHLTQGGWYDDSSESARASRLADEKFGKDT 65 Query 65 RSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLG----WAGYLRAS----- 115 +S I+ I G+TV+ PA + V +L + +QDH D+ + W G+ A+ Sbjct 66 KSDVILLISTTEKGETVESPAIADAVFHQLAKIKQDHADKTVDIISLWGGWNHAAPQTWP 125 Query 116 QAT--GMATA------------DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ-RLDGGT 160 QAT G A A D ++TFVSI + G DD + NY+A++ + + G Sbjct 126 QATPDGHAPAAIPAIKSRLESPDGEHTFVSIGIAGKDDTERVANYRAVSKEFNFSVPGAK 185 Query 161 VKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGA 220 V++ GL V +++ T+ D RME++A+PL A+++FFVFGGV++A LP +VGGL I G Sbjct 186 VEVTGLLAVTDSINETMGKDVFRMEIIAVPLTALIMFFVFGGVVSAALPAIVGGLAILGG 245 Query 221 LGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVIT 280 G+M+ LA F V FAQPVVSL+GLGIA+DYGLF+VSRFREE++EGY T AVRRTV + Sbjct 246 YGLMKILAEFTDVSAFAQPVVSLVGLGIAVDYGLFMVSRFREELSEGYPTGVAVRRTVQS 305 Query 281 AGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHV 340 +GRTV +SA+L+V S +LLFPQGFL+S+ YA S+ +A +S+TVLPA L +LG V Sbjct 306 SGRTVAYSALLVVVSIACVLLFPQGFLRSVAYACGISITFAAFISLTVLPAMLSVLGPRV 365 Query 341 DALGVRTLFRVPFLANWKISAAYLNWLAD-----RLQRTKTREEVEAGFWGKLVNRVMKR 395 DAL + T+ R FL LN++AD +RT++RE+V FWGKL VM Sbjct 366 DALSLDTILR--FL--------RLNFIADLPLMRYFKRTRSREQVMDSFWGKLSAWVMNH 415 Query 396 PVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLV 455 PV P++ ++LLI+P + GISEKYLPP N+ R + F++ FP RT L ++ Sbjct 416 PVKLIVPVIAFLVLLILPALNIQFAGISEKYLPPDNATRLGLDHFEQYFPKERTEQLKIM 475 Query 456 IQTSNHQPVTDAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVR-----V 510 + + Q Q+ DI SKA I GF A+ A DPS R V Sbjct 476 VIGGDQQ-----QLYDIASKANEIPGFT----------GHFAFPDAAHPDPSHRTDGVAV 520 Query 511 LQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTT 570 +NGLI+ A++ + LR I P G TV V GTPALE DSI +FA MPLM ++L+ T Sbjct 521 AENGLIDRGTAAEAVKRLREIQTPSGPTVWVFGTPALEQDSIDAVFAGMPLMGLLLVVIT 580 Query 571 IVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLI 630 ++MFLAFGSVVLPIKA ++S L+LGST+G+LTWIF DGH S LNFTP PL A V+ L+ Sbjct 581 TIMMFLAFGSVVLPIKAVILSVLSLGSTLGVLTWIFQDGHGSGLLNFTPYPLMAVVLALL 640 Query 631 IALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVF 690 +ALV+G+S+DYEVFL++R VEAR RG+ST++A G A+ GR+ITAAAL++ VVA AF F Sbjct 641 VALVYGVSSDYEVFLLARTVEARGRGLSTEDATCEGAASGGRVITAAALVLLVVASAFGF 700 Query 691 SDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIH 750 SDLVMMKYLAFGL+AALL+D T VRM LVP+ MKLLGD+ WWAP W +RLQ R+GLGEI Sbjct 701 SDLVMMKYLAFGLIAALLIDVTAVRMILVPATMKLLGDENWWAPHWMKRLQERLGLGEIE 760 Query 751 LPDERK 756 LPDER Sbjct 761 LPDERH 766 >gi|296395212|ref|YP_003660096.1| MMPL domain-containing protein [Segniliparus rotundus DSM 44985] gi|296182359|gb|ADG99265.1| MMPL domain protein [Segniliparus rotundus DSM 44985] Length=983 Score = 639 bits (1648), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/791 (49%), Positives = 514/791 (65%), Gaps = 60/791 (7%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +F G VYR R VI VMVA+ + GV+G+ +G H++Q G+YDD S+S +AS L D+ Sbjct 8 LFGAIGAFVYRARVPVITVMVAIFVALGVYGIDIGDHLSQGGWYDDNSESARASRLSDEK 67 Query 61 YGRD-RSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLG----WAGYLRAS 115 +G+D +S I+ I G TV+ PA + V ++L +QDHPD+ + W + A+ Sbjct 68 FGQDTKSDVILFITATDPGSTVESPAIADAVFNQLAAIKQDHPDKTVDIFSLWGVWNHAA 127 Query 116 QAT-------GMATA------------DKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ-R 155 T G A A D K+TFVSI ++G DD +NNY+++ Sbjct 128 PQTWPKATPDGHAPAAIPLLKQRLESPDGKHTFVSIGIQGKDDTERVNNYRSVRDAFTFS 187 Query 156 LDGGTVKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGL 215 + G V+ GL V +A+ T+ D RME++A+PL A+++FFVFGGV+AA LP +VGGL Sbjct 188 VPGAKVETTGLLAVTDAINETMGKDVHRMELIAVPLTALIMFFVFGGVVAAILPAIVGGL 247 Query 216 CIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVR 275 I G G+++ L F V FAQPVVSL+GLGIA+DYGLF+VSRFREE+AEGY + AVR Sbjct 248 AILGGNGLIKLLTEFTEVSSFAQPVVSLVGLGIAVDYGLFMVSRFREELAEGYPIDIAVR 307 Query 276 RTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGI 335 RTV +AGRTV +SA+L+V S G+LLFPQGFL+S+ YA S+ +A +S+TVLPA L Sbjct 308 RTVQSAGRTVVYSALLVVVSIAGVLLFPQGFLRSVAYACGVSIAFAAFISLTVLPAMLSF 367 Query 336 LGKHVDALGVRTLFRVPFLANWKISAAYLNWLAD-----RLQRTKTREEVEAGFWGKLVN 390 LG VDAL + T+ R FL LN +AD +RT++RE+V GFWGKL Sbjct 368 LGHRVDALSLDTILR--FL--------RLNVIADLPLMRYFKRTRSREQVMDGFWGKLSA 417 Query 391 RVMKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTN 450 VM+ PV P++ +++LLI+P + GISEKYLPP N R + F++ FP RT Sbjct 418 WVMRHPVKLMVPVLALLLLLILPALNIKFAGISEKYLPPDNPTRLGLQHFEETFPKERTE 477 Query 451 PLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPS--- 507 L +++ + Q Q+ + SKA I GF + ++ A+ DPS Sbjct 478 QLKIMVLGGDPQ-----QLNQVASKANEIKGFT----------GQFSFPDAANPDPSRLT 522 Query 508 --VRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVI 565 V V N LIN A++ + +LRA+ P G T+ + GTPALE DSI +FA PLM + Sbjct 523 DGVAVATNSLINRDTAAEAVKQLRALKAPPGTTIWIFGTPALEQDSIDAVFAGFPLMGFL 582 Query 566 LLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAP 625 L+ T V+MFLAFGSVVLP+KA ++S L+LGST+G+LTWIF +GH + LNFTP PL A Sbjct 583 LIVITTVMMFLAFGSVVLPVKAVILSVLSLGSTLGVLTWIFQEGHGAGLLNFTPYPLMAV 642 Query 626 VIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVA 685 V+ L++ALV+GLS+DYEVFL++R VEAR RG+ST+ A G A+ GR+ITAAAL++ VVA Sbjct 643 VLALLVALVYGLSSDYEVFLLARTVEARGRGLSTEAATCEGAASGGRVITAAALVLLVVA 702 Query 686 GAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIG 745 AF FS+LVMMKYLAFGL+AALL+D T +RM LVP+ MKLLGD+ WWAPRW +R Q R+G Sbjct 703 SAFGFSELVMMKYLAFGLIAALLIDVTAIRMILVPATMKLLGDENWWAPRWMKRFQERLG 762 Query 746 LGEIHLPDERK 756 LGEI +PDER Sbjct 763 LGEIAMPDERH 773 >gi|319949688|ref|ZP_08023721.1| integral membrane protein MmpL5 [Dietzia cinnamea P4] gi|319436650|gb|EFV91737.1| integral membrane protein MmpL5 [Dietzia cinnamea P4] Length=822 Score = 631 bits (1627), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 391/825 (48%), Positives = 520/825 (64%), Gaps = 58/825 (7%) Query 1 VFAWWGRTVYRYRFIVIGV----MVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVL 56 +F GR V R R +V+ M L L G FG G Q GF D S A L Sbjct 1 MFNSLGRFVARRRVLVVICSVVVMAFLSLAGSAFGNPFG----QGGFEDPDSGWATAEQL 56 Query 57 GDQVYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQ 116 + YGRD G +V + AP G +VDDPA+ + + L + ++PD+V G ++ +Q Sbjct 57 EQEAYGRDALGDVVVSYHAPEGTSVDDPAFQEPIRQSLESIRTENPDRVTGVTSFV-FNQ 115 Query 117 ATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGT 176 + + D SI + G+ ++ IL N++AI D ++G +AGLQPVA AL Sbjct 116 SPALVNRDAGIAVASIQIAGEAEE-ILQNFRAIE-DQIPVEGIETDIAGLQPVAGALQDG 173 Query 177 IATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYF 236 + D R E++ALPLV ++L VFGGV+AA LPV VG L I G+LG + L++ PV+ F Sbjct 174 MDADLVRAELIALPLVFLLLIVVFGGVVAAFLPVAVGVLTILGSLGALHLLSLVTPVNSF 233 Query 237 AQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASA 296 AQ VV+LIGLG+AIDYGLF+VSRFREE+AEGY + AVRR+V TAGRTV FSAV++ + Sbjct 234 AQNVVTLIGLGLAIDYGLFVVSRFREEMAEGYPPDAAVRRSVATAGRTVVFSAVMVGVTL 293 Query 297 IGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLAN 356 GLL+FPQ FLKS+ Y IA+V+L+A LS+T+LPA L +LG VDALG++ Sbjct 294 SGLLVFPQDFLKSVAYGAIAAVILAAALSVTLLPAVLMLLGHRVDALGIK---------- 343 Query 357 WKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGK 416 R+QR +TREEVE G +G++ + MKRPV A P+V++++ LIIP Sbjct 344 -------------RMQRHRTREEVENGLFGRVADFSMKRPVAVAIPVVVVLVALIIPFSG 390 Query 417 LSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKA 476 + GGI+E YLPP N R AQEE+D+ FPG RT+P+ LV+ S+ A ++ IRS A Sbjct 391 VKFGGINETYLPPDNPTRVAQEEYDQNFPGTRTDPVKLVVLGSDG-----ATLSQIRSAA 445 Query 477 MAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKG 536 G P + Q+ S+ V VLQ G+++ A++ + L++ P G Sbjct 446 NEAPGLTGPFQFARSGGQD-------SQGREVVVLQAGVVDRNAATETVEYLQSFPIPAG 498 Query 537 ITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLG 596 V VGG PA+E DS+ L A +P V+ +L T +LMFLAFGS+VLPIKA +M+ L LG Sbjct 499 TEVFVGGNPAMEKDSVDALIAGLPWFVLYVLVATTLLMFLAFGSLVLPIKAAIMNMLGLG 558 Query 597 STMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERG 656 +T+GILTWIFVDGH S L FTP PLT+PV+ L++A+++GLSTDYEVFLVSRMVEAR RG Sbjct 559 ATLGILTWIFVDGHLSGLLGFTPGPLTSPVVVLLMAIIYGLSTDYEVFLVSRMVEARSRG 618 Query 657 MSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRM 716 T EAIR G A TGRIIT+AALI+ VV GAF FS++VMMKY+AFG++AAL++DATV+RM Sbjct 619 ARTAEAIRSGVAQTGRIITSAALILIVVTGAFAFSEIVMMKYIAFGMIAALIIDATVIRM 678 Query 717 FLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTA--GLV 774 LVP+VM++LG D WWAPRW +R+Q RIGLGE + DE + + GRPA T G Sbjct 679 LLVPAVMQMLGTDNWWAPRWMKRVQERIGLGEAEIDDEPE--LLTGRPADTDGTGPTGAA 736 Query 775 AARAAGDPRPPHDPTHPLA----ESPRPARSSPASSPELTPALEA 815 + A D R P + P A + P PA P S E P EA Sbjct 737 TSVAVLD-REPAGTSAPQARDAEQEPEPA---PESETEPAPGSEA 777 >gi|145221060|ref|YP_001131738.1| RND superfamily drug efflux protein [Mycobacterium gilvum PYR-GCK] gi|315441969|ref|YP_004074848.1| hypothetical protein Mspyr1_02990 [Mycobacterium sp. Spyr1] gi|145213546|gb|ABP42950.1| drug exporters of the RND superfamily-like protein [Mycobacterium gilvum PYR-GCK] gi|315260272|gb|ADT97013.1| hypothetical protein Mspyr1_02990 [Mycobacterium sp. Spyr1] Length=1110 Score = 617 bits (1591), Expect = 3e-174, Method: Compositional matrix adjust. Identities = 340/585 (59%), Positives = 422/585 (73%), Gaps = 44/585 (7%) Query 295 SAIGLLLFPQGFLKSLTYATIAS----------VMLSAILSITVLPACLGILGKHVDALG 344 + IGL L G L + Y IA+ V++ ++ + V+ L L ++V Sbjct 410 TMIGLALGYVGLLGWIAYLAIANRESLGDGLYWVLIGVVIFVAVVAGGLA-LARYV---- 464 Query 345 VRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIV 404 L R P + W ++ WLA++ Q+TKTR EVE GFWGKLVN VMKRP+ FAAPI+ Sbjct 465 --PLARGPIV--W-----WVEWLAEKTQKTKTRAEVEKGFWGKLVNVVMKRPIAFAAPIL 515 Query 405 IIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPV 464 I MILLI+P+G+L+LGGISEKYLPP N VR AQE+FD+ FPG+RT PLTLVI+ + +PV Sbjct 516 IGMILLILPLGQLALGGISEKYLPPDNGVRTAQEDFDRTFPGFRTEPLTLVIERQDGEPV 575 Query 465 TDAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKK 524 TD Q+A++R+KAM + GFI+PDNDP+ MWQERA +KDPS+RVLQNGL++ DAS+K Sbjct 576 TDQQLAEVRAKAMTVPGFIDPDNDPSKMWQERAAQDTGTKDPSIRVLQNGLVDRNDASQK 635 Query 525 LTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLP 584 + ELR+I PP+G+ + VGGTPALE DSIH LF K+PLM ++L+ TT +LMFLAFGS+VLP Sbjct 636 IDELRSIQPPRGVDISVGGTPALEQDSIHSLFDKLPLMGLVLIVTTTILMFLAFGSIVLP 695 Query 585 IKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVF 644 IKA LMSALTLGSTMGILTW+FVDGH S +N+TP PL AP+IGLIIA+++GLSTDYEVF Sbjct 696 IKAALMSALTLGSTMGILTWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVF 755 Query 645 LVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLM 704 LVSRMVEARERG+ST EAIRIGTA TGR+IT AAL++AVVAGAFVFSDLVMMKYLAFGL+ Sbjct 756 LVSRMVEARERGLSTAEAIRIGTATTGRLITGAALVLAVVAGAFVFSDLVMMKYLAFGLL 815 Query 705 AALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRP-VSNGR 763 ALLLDAT++RMFLVP++MKLLGDDCWWAPRW +R+Q ++GLGE LPDERKRP V R Sbjct 816 IALLLDATIIRMFLVPAIMKLLGDDCWWAPRWMKRIQEKLGLGETELPDERKRPAVREER 875 Query 764 --PARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAA 821 PA V AG A PPHDPTH P P R +P P +T + P Sbjct 876 EAPAEALVGAGGPPVMAPPRALPPHDPTH-----PAPGRPAPVRPPAVTTRMGTPTYP-D 929 Query 822 PSGASTTRM-----------QIGSSTEPPTTRLAAAGRSVQSPAS 855 P+ A TTR+ + EP TTRL+ A +V++ S Sbjct 930 PAAAGTTRIPTAPPRPPVTPPPPAQDEPQTTRLSIAKNAVRNAVS 974 Score = 494 bits (1273), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 243/361 (68%), Positives = 292/361 (81%), Gaps = 7/361 (1%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGRTVY+YR+IVIGVMVALCLGGGV+G+SLG+HVTQSGFYD+GSQSV AS++ D+ Sbjct 1 MFAWWGRTVYQYRYIVIGVMVALCLGGGVYGMSLGQHVTQSGFYDEGSQSVHASLVSDEA 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATG- 119 YGRDR+ H+VAI P G+ VD+P W +KV ELN ++ D+++ W G+LRA A Sbjct 61 YGRDRTSHVVAILTPPDGEKVDNPEWMEKVTGELNDLVAENEDRIVSWVGWLRAPDAAAE 120 Query 120 ----MATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 M T D TFVSIPLKG++DD IL NY+AI P L +++ G ++LAGLQP+A LTG Sbjct 121 TVQQMKTEDLSKTFVSIPLKGENDDEILKNYQAIEPQLSQVNDGGIQLAGLQPLASELTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 TI DQ+R EV A+PLV VVLFFVFGGVIAA LP ++GGL IAGALGIMR A F PVH+ Sbjct 181 TIGEDQKRAEVAAIPLVCVVLFFVFGGVIAAALPGIIGGLTIAGALGIMRVFAEFMPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVV+L+GLGIAIDYGLF+VSRFREEIAEGYDTE AVRR V+T+GRTV FSAV++VAS Sbjct 241 FAQPVVTLMGLGIAIDYGLFMVSRFREEIAEGYDTEAAVRRAVMTSGRTVMFSAVILVAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 ++ LLLFPQGFLKS+TYA IASVML+AILS+TVLPA L ILG VDALGVR L + F+ Sbjct 301 SVPLLLFPQGFLKSITYAIIASVMLAAILSVTVLPAALAILGPRVDALGVRWLLK--FVN 358 Query 356 N 356 N Sbjct 359 N 359 Score = 62.0 bits (149), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 67/254 (27%), Positives = 120/254 (48%), Gaps = 35/254 (13%) Query 154 QRLDGGTVKLAGLQP---VAEALTGTIATDQRRMEVL--ALPLVAVVL--------FFVF 200 Q++D +L +QP V ++ GT A +Q + L LPL+ +VL F F Sbjct 634 QKID----ELRSIQPPRGVDISVGGTPALEQDSIHSLFDKLPLMGLVLIVTTTILMFLAF 689 Query 201 GGVIAAGLPVMVGGLCIAGALGIMRFLAIFGP----VHYFAQPVVS-LIGL------GIA 249 G ++ ++ L + +GI+ ++ + G ++Y QP+++ +IGL G++ Sbjct 690 GSIVLPIKAALMSALTLGSTMGILTWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLS 749 Query 250 IDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKS 309 DY +F+VSR E G T A+R T GR +T +A+++ A + +K Sbjct 750 TDYEVFLVSRMVEARERGLSTAEAIRIGTATTGRLITGAALVLAVVAGAFVFSDLVMMKY 809 Query 310 LTYATIASVMLSA-ILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLA 368 L + + +++L A I+ + ++PA + +LG R + R+ K+ L Sbjct 810 LAFGLLIALLLDATIIRMFLVPAIMKLLGDDC-WWAPRWMKRI----QEKLGLGETE-LP 863 Query 369 DRLQRTKTREEVEA 382 D +R REE EA Sbjct 864 DERKRPAVREEREA 877 Score = 54.7 bits (130), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 44/179 (25%), Positives = 86/179 (49%), Gaps = 22/179 (12%) Query 550 DSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDG 609 D A +PL+ V+L F FG V+ ++ LT+ +GI+ +F + Sbjct 185 DQKRAEVAAIPLVCVVL--------FFVFGGVIAAALPGIIGGLTIAGALGIMR-VFAE- 234 Query 610 HFSKWLNFTPTPLTA-PVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTA 668 F P A PV+ L + G++ DY +F+VSR E G T+ A+R Sbjct 235 -------FMPVHFFAQPVVTL---MGLGIAIDYGLFMVSRFREEIAEGYDTEAAVRRAVM 284 Query 669 ATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLG 727 +GR + +A+I+ + + +K + + ++A+++L A ++ + ++P+ + +LG Sbjct 285 TSGRTVMFSAVILVASSVPLLLFPQGFLKSITYAIIASVML-AAILSVTVLPAALAILG 342 >gi|108797151|ref|YP_637348.1| RND superfamily drug efflux protein [Mycobacterium sp. MCS] gi|119866236|ref|YP_936188.1| RND superfamily drug efflux protein [Mycobacterium sp. KMS] gi|108767570|gb|ABG06292.1| drug exporters of the RND superfamily-like protein [Mycobacterium sp. MCS] gi|119692325|gb|ABL89398.1| drug exporters of the RND superfamily-like protein [Mycobacterium sp. KMS] Length=1093 Score = 617 bits (1590), Expect = 4e-174, Method: Compositional matrix adjust. Identities = 367/638 (58%), Positives = 445/638 (70%), Gaps = 77/638 (12%) Query 363 YLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGI 422 +L+WLA++ Q+TKTR EVE GFWGKLV VMKRP FA PI+++MILLIIP+G+LSLGGI Sbjct 477 WLHWLAEKTQKTKTRAEVEQGFWGKLVTHVMKRPGTFAFPIIVVMILLIIPLGQLSLGGI 536 Query 423 SEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGF 482 SEKYLPP NSVRQAQE+FD+ FPG+RT PLT+V+++ N PVTD Q+ADIR+KAM+I GF Sbjct 537 SEKYLPPDNSVRQAQEDFDRSFPGFRTEPLTIVLKSDNGDPVTDQQVADIRAKAMSISGF 596 Query 483 IEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVG 542 I+PDNDP+ MWQER+ G S+DPSVRV+QNGL N DA+ K+ ELRA++PP+G++V VG Sbjct 597 IDPDNDPSKMWQERSVQEGGSEDPSVRVIQNGLENRNDAATKIEELRALSPPRGVSVWVG 656 Query 543 GTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGIL 602 GTPALE DSIH LF ++PLMV IL+ TT +LMFLAFGS+VLPIKA LMSALTLGSTMGIL Sbjct 657 GTPALEQDSIHSLFDRLPLMVTILIVTTTILMFLAFGSLVLPIKAALMSALTLGSTMGIL 716 Query 603 TWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEA 662 TW+FVDGH S +N+TP PL AP+IGLIIA+++GLSTDYEVFLVSRMVEAR RG+ST EA Sbjct 717 TWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARARGLSTAEA 776 Query 663 IRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSV 722 IR+GTA TGR+IT AAL++AVVAGAFVFSDLVMMKYLAFGL+ ALLLDAT++RMFLVP++ Sbjct 777 IRVGTATTGRLITGAALVLAVVAGAFVFSDLVMMKYLAFGLLLALLLDATIIRMFLVPAI 836 Query 723 MKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARA--AG 780 MK+LGDDCWWAPRW +RLQ R+GLGE+ LPDERKRP+ P LV A A Sbjct 837 MKMLGDDCWWAPRWMKRLQERLGLGEVELPDERKRPLVRD----PSEDQALVGAGAPVPP 892 Query 781 DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGS---STE 837 PRPPHDPTHP E R P P P L PS A T+R+ E Sbjct 893 RPRPPHDPTHPGVE----GRVGPTRIPPGPPRLN------GPSVAGTSRIPTNRPAPGHE 942 Query 838 PPTTRLAAAGRSVQ---SPASTP-PPTPTPPS---------------------------- 865 PPTTRL+ A +V+ + A+TP P PT P+ Sbjct 943 PPTTRLSMAKNAVRGAVNTATTPRAPRPTGPAPKREEREIESWLGELRGGPAGPGGGQPP 1002 Query 866 ---APSAGQTRAMPLAANRSTDAAG----------------DPAEPTAALPIIRSDGDDS 906 PSA T AM A R + ++ T +P + G DS Sbjct 1003 RPPQPSAEPTTAMRAGAPRPEPEPEGNEPTTAIPVQRPPQPEESDATTKIPTQQDAGTDS 1062 Query 907 EAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 A+TE+LNA Q+RRGGG +SA +LLRREGR+ Sbjct 1063 -ASTEKLNA-----PEEQKRRGGG-MSAAELLRREGRM 1093 Score = 504 bits (1298), Expect = 3e-140, Method: Compositional matrix adjust. Identities = 242/355 (69%), Positives = 291/355 (82%), Gaps = 5/355 (1%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGR VYRYR+IVIGVMVALC+GGG++G+SLG +VTQSGFYD+GSQSVQASV GD+V Sbjct 1 MFAWWGRNVYRYRYIVIGVMVALCIGGGIYGISLGNNVTQSGFYDEGSQSVQASVAGDEV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATG- 119 YGRDR+ H+VAI P G+ VD+P W ++VV EL+ +DHPDQV+ W G+LRA A Sbjct 61 YGRDRTSHVVAILTPPDGEKVDNPEWQREVVGELDALVKDHPDQVVSWVGWLRAPDAASA 120 Query 120 ----MATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 M T D TFVS+PLKGD DD IL NY+ I PDLQ ++ G ++LAGL P+A LTG Sbjct 121 TVQQMKTEDLSKTFVSVPLKGDTDDEILKNYQVIEPDLQEINDGNIQLAGLNPLASELTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 +I DQ+R EV A+PLV VVLFFVFGGVIAA LP ++GGL IAGALGIMR LA PVH+ Sbjct 181 SIGEDQKRAEVAAIPLVCVVLFFVFGGVIAAALPGLIGGLTIAGALGIMRLLAEIMPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVV+L+GLGIA+DYGLF+VSRFREE+AEGYDTE AVRRTV+T+GRT+ FSAV++VAS Sbjct 241 FAQPVVTLMGLGIAVDYGLFMVSRFREELAEGYDTEAAVRRTVMTSGRTIMFSAVILVAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFR 350 ++ LLLFPQGFLKS+TYA IASVML+A+LSITVL A L ILG VDALGV+TL + Sbjct 301 SVPLLLFPQGFLKSITYAIIASVMLAAVLSITVLAAALAILGPRVDALGVKTLIK 355 Score = 51.6 bits (122), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 44/180 (25%), Positives = 83/180 (47%), Gaps = 24/180 (13%) Query 550 DSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWI--FV 607 D A +PL+ V+L F FG V+ L+ LT+ +GI+ + + Sbjct 185 DQKRAEVAAIPLVCVVL--------FFVFGGVIAAALPGLIGGLTIAGALGIMRLLAEIM 236 Query 608 DGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGT 667 HF PV+ L + G++ DY +F+VSR E G T+ A+R Sbjct 237 PVHF----------FAQPVVTL---MGLGIAVDYGLFMVSRFREELAEGYDTEAAVRRTV 283 Query 668 AATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLG 727 +GR I +A+I+ + + +K + + ++A+++L A V+ + ++ + + +LG Sbjct 284 MTSGRTIMFSAVILVASSVPLLLFPQGFLKSITYAIIASVML-AAVLSITVLAAALAILG 342 Score = 51.6 bits (122), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 52/188 (28%), Positives = 92/188 (49%), Gaps = 28/188 (14%) Query 175 GTIATDQRRMEVL--ALPLVAVVL--------FFVFGGVIAAGLPVMVGGLCIAGALGIM 224 GT A +Q + L LPL+ +L F FG ++ ++ L + +GI+ Sbjct 657 GTPALEQDSIHSLFDRLPLMVTILIVTTTILMFLAFGSLVLPIKAALMSALTLGSTMGIL 716 Query 225 RFLAIFGP----VHYFAQPVVS-LIGL------GIAIDYGLFIVSRFREEIAEGYDTETA 273 ++ + G ++Y QP+++ +IGL G++ DY +F+VSR E A G T A Sbjct 717 TWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARARGLSTAEA 776 Query 274 VRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTY----ATIASVMLSAILSITVL 329 +R T GR +T A L++A G +F L + Y +A ++ + I+ + ++ Sbjct 777 IRVGTATTGRLIT-GAALVLAVVAGAFVFSD--LVMMKYLAFGLLLALLLDATIIRMFLV 833 Query 330 PACLGILG 337 PA + +LG Sbjct 834 PAIMKMLG 841 >gi|126432773|ref|YP_001068464.1| RND superfamily drug efflux protein [Mycobacterium sp. JLS] gi|126232573|gb|ABN95973.1| drug exporters of the RND superfamily-like protein [Mycobacterium sp. JLS] Length=1089 Score = 616 bits (1588), Expect = 7e-174, Method: Compositional matrix adjust. Identities = 364/631 (58%), Positives = 444/631 (71%), Gaps = 67/631 (10%) Query 363 YLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLGGI 422 +L+WLA++ Q+TKTR EVE GFWGKLV VMKRP FA PI+++MILLIIP+G+LSLGGI Sbjct 477 WLHWLAEKTQKTKTRAEVEQGFWGKLVTHVMKRPGTFAFPIIVVMILLIIPLGQLSLGGI 536 Query 423 SEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIGGF 482 SEKYLPP NSVRQAQE+FD+ FPG+RT PLT+V+++ N PVTD Q+ADIR+KAM+I GF Sbjct 537 SEKYLPPDNSVRQAQEDFDRSFPGFRTEPLTIVLKSDNGDPVTDQQVADIRAKAMSISGF 596 Query 483 IEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVG 542 I+PDNDP+ MWQER+ G S+DPSVRV+QNGL N DA+ K+ ELRA++PP+G++V VG Sbjct 597 IDPDNDPSKMWQERSVQEGGSEDPSVRVIQNGLENRNDAATKIEELRALSPPRGVSVWVG 656 Query 543 GTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGIL 602 GTPALE DSIH LF ++PLMV IL+ TT +LMFLAFGS+VLPIKA LMSALTLGSTMGIL Sbjct 657 GTPALEQDSIHSLFDRLPLMVTILIVTTTILMFLAFGSLVLPIKAALMSALTLGSTMGIL 716 Query 603 TWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEA 662 TW+FVDGH S +N+TP PL AP+IGLIIA+++GLSTDYEVFLVSRMVEAR RG+ST EA Sbjct 717 TWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARARGLSTAEA 776 Query 663 IRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSV 722 IR+GTA TGR+IT AAL++AVVAGAFVFSDLVMMKYLAFGL+ ALLLDAT++RMFLVP++ Sbjct 777 IRVGTATTGRLITGAALVLAVVAGAFVFSDLVMMKYLAFGLLLALLLDATIIRMFLVPAI 836 Query 723 MKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDP 782 MK+LGDDCWWAPRW +RLQ R+GLGE+ LPDERKRP+ PA G A P Sbjct 837 MKMLGDDCWWAPRWMKRLQERLGLGEVELPDERKRPLVRD-PAEDQALVG-AGAPVPPRP 894 Query 783 RPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGS---STEPP 839 RPPHDPTHP E R P P P L PS A T+R+ EPP Sbjct 895 RPPHDPTHPGVE----GRVGPTRIPPGPPRLN------GPSVAGTSRIPTNRPAPGHEPP 944 Query 840 TTRLAAAGRSVQ---SPASTP-PPTPTPPSAPSA--------GQTRAMP--LAANRSTDA 885 TTRL+ A +V+ + A+TP P PT P+ G+ R P + Sbjct 945 TTRLSMAKNAVRGAVNTATTPRAPRPTGPAPKREEREIESWLGELRGGPSNPGGGQPPRP 1004 Query 886 AGDPAEPTAAL--------------------PIIR-SDGDDSEA-----------ATEQL 913 AEPT A+ P+ R ++S+A +TE+L Sbjct 1005 PQPSAEPTTAMRAGAPKPEPEPEGNEPTTAIPVQRPPQPEESDATTKIPTQQDPKSTEKL 1064 Query 914 NARGTSDKTRQRRRGGGALSAQDLLRREGRL 944 NA Q+RRGGG +SA +LLRREGR+ Sbjct 1065 NA-----PEEQKRRGGG-MSAAELLRREGRM 1089 Score = 506 bits (1302), Expect = 1e-140, Method: Compositional matrix adjust. Identities = 243/355 (69%), Positives = 292/355 (83%), Gaps = 5/355 (1%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV 60 +FAWWGR VYRYR+IVIGVMVALC+GGG++G+SLG +VTQSGFYD+GSQSVQASV GD+V Sbjct 1 MFAWWGRNVYRYRYIVIGVMVALCIGGGIYGISLGNNVTQSGFYDEGSQSVQASVAGDEV 60 Query 61 YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATG- 119 YGRDR+ H+VAI P G+ VD+P W ++VV EL+ +DHPDQV+ W G+LRA A Sbjct 61 YGRDRTSHVVAILTPPDGEKVDNPEWQREVVGELDALVKDHPDQVVSWVGWLRAPDAASE 120 Query 120 ----MATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTG 175 M TAD TFVS+PLKGD DD IL NY+ I PDLQ ++ G ++LAGL P+A LTG Sbjct 121 TVQQMKTADLSKTFVSVPLKGDTDDEILKNYQVIEPDLQEINDGNIQLAGLNPLASELTG 180 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 +I DQ+R EV A+PLV VVLFFVFGGVIAA LP ++GGL IAGALGIMR LA PVH+ Sbjct 181 SIGEDQKRAEVAAIPLVCVVLFFVFGGVIAAALPGLIGGLTIAGALGIMRLLAEIMPVHF 240 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQPVV+L+GLGIA+DYGLF+VSRFREE+AEGYDTE AVRRTV+T+GRT+ FSAV++VAS Sbjct 241 FAQPVVTLMGLGIAVDYGLFMVSRFREELAEGYDTEAAVRRTVMTSGRTIMFSAVILVAS 300 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFR 350 ++ LLLFPQGFLKS+TYA IASVML+A+LSITVL A L ILG VDALGV+TL + Sbjct 301 SVPLLLFPQGFLKSITYAIIASVMLAAVLSITVLAAALAILGPRVDALGVKTLIK 355 Score = 52.0 bits (123), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 44/180 (25%), Positives = 83/180 (47%), Gaps = 24/180 (13%) Query 550 DSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWI--FV 607 D A +PL+ V+L F FG V+ L+ LT+ +GI+ + + Sbjct 185 DQKRAEVAAIPLVCVVL--------FFVFGGVIAAALPGLIGGLTIAGALGIMRLLAEIM 236 Query 608 DGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGT 667 HF PV+ L + G++ DY +F+VSR E G T+ A+R Sbjct 237 PVHF----------FAQPVVTL---MGLGIAVDYGLFMVSRFREELAEGYDTEAAVRRTV 283 Query 668 AATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLG 727 +GR I +A+I+ + + +K + + ++A+++L A V+ + ++ + + +LG Sbjct 284 MTSGRTIMFSAVILVASSVPLLLFPQGFLKSITYAIIASVML-AAVLSITVLAAALAILG 342 Score = 51.6 bits (122), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 52/188 (28%), Positives = 92/188 (49%), Gaps = 28/188 (14%) Query 175 GTIATDQRRMEVL--ALPLVAVVL--------FFVFGGVIAAGLPVMVGGLCIAGALGIM 224 GT A +Q + L LPL+ +L F FG ++ ++ L + +GI+ Sbjct 657 GTPALEQDSIHSLFDRLPLMVTILIVTTTILMFLAFGSLVLPIKAALMSALTLGSTMGIL 716 Query 225 RFLAIFGP----VHYFAQPVVS-LIGL------GIAIDYGLFIVSRFREEIAEGYDTETA 273 ++ + G ++Y QP+++ +IGL G++ DY +F+VSR E A G T A Sbjct 717 TWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARARGLSTAEA 776 Query 274 VRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTY----ATIASVMLSAILSITVL 329 +R T GR +T A L++A G +F L + Y +A ++ + I+ + ++ Sbjct 777 IRVGTATTGRLIT-GAALVLAVVAGAFVFSD--LVMMKYLAFGLLLALLLDATIIRMFLV 833 Query 330 PACLGILG 337 PA + +LG Sbjct 834 PAIMKMLG 841 >gi|296138103|ref|YP_003645346.1| large membrane protein [Tsukamurella paurometabola DSM 20162] gi|296026237|gb|ADG77007.1| large membrane protein [Tsukamurella paurometabola DSM 20162] Length=997 Score = 611 bits (1576), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 381/917 (42%), Positives = 522/917 (57%), Gaps = 84/917 (9%) Query 1 VFAWWGRTVYRYRFIVIGVMVALCLGGGVFG-LSLGKHVTQSGFYDDGSQSVQASVLGDQ 59 +FA GR Y +R+ +I V+ GV+G L LG +G YD+ S SV AS L D+ Sbjct 1 MFAAIGRFSYAFRYTIIAVLFVSIAATGVWGFLGLGSKTKMNGLYDEKSDSVAASKLTDE 60 Query 60 VYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDE-----LNRFQQDHPDQVLGWAG---- 110 GR I+ + +A GK V D A K V+ L++F + PD L A Sbjct 61 ANGRFAQSDILVLVKAADGKKVTD-AEVKDSVESARTKILDQFAK-GPDAKLYGADAENT 118 Query 111 YLRASQATGMATADKKYT----------FVSIPLKGDDDDTILNNYKAIAPDLQRL---- 156 +R + T + AD + F ++PLK +DD ++ I ++ + Sbjct 119 SMRPASYTTLPAADNPFVRNEANGESWGFFTLPLKSNDDTQRGLDWADIREPIRDILKTQ 178 Query 157 -DGG-TVKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGG 214 DG + AGL PV +T + DQ++ E++ALPLVA+VLFFV+GG++AA LP+++G Sbjct 179 ADGKFEARFAGLVPVTSEVTEGVQRDQKKAELIALPLVAIVLFFVYGGIVAAVLPMIIGV 238 Query 215 LCIAGALGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAV 274 + I ++ I LA F V+ F P++SLIGLGIA DYGLF+VSRFREE+ EGYDT TAV Sbjct 239 MTIGASMAIASVLAQFMEVNLFVGPIISLIGLGIAHDYGLFMVSRFREELDEGYDTPTAV 298 Query 275 RRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLG 334 RRTV+TAGRT+ S++LIV + L + P G L S+ + V ++A+LS+ +LPA L Sbjct 299 RRTVMTAGRTIVMSSLLIVGALACLYISPLGLLTSMATGALLGVFIAALLSLVLLPAMLA 358 Query 335 ILGKHVDALGVRTLFRVPFLANWKIS--AAYLNWLADRLQRTKTREEVEAGFWGKLVNRV 392 +LG V AL + WK+ ++W A++ + KT+ +E G WGK+ + V Sbjct 359 VLGPRVFALSFHWFLTI--FDKWKLPLIGGIIHWAAEKTGKPKTKANIENGMWGKVTDAV 416 Query 393 MKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPL 452 M++P+ + +V +++ + IPV L GGIS+ YLPPTN RQAQ++F + FP Y + Sbjct 417 MRKPIAYTVGVVTLLLAITIPVIGLQFGGISQTYLPPTNETRQAQDKFFETFPAYTGQSI 476 Query 453 TLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDNDPANMWQER-----AYAVGASKDPS 507 +V ++ DAQI + +A I GF+ DPA+ R A A D S Sbjct 477 QIVFTNAD-----DAQIKQVLDEANKIPGFVH--TDPADRNSSRFSPPTAAVATAKSDGS 529 Query 508 ------------VRVLQNGLINPADA---SKKLTELRAIT-----PPKGITVLVGGTPAL 547 VR L +P D S+ + ++R IT KG+ +VGG P L Sbjct 530 PLQIRGEGPEVKVRTSNGNLQDPNDTKAVSQAVEQIRGITMDGADASKGVGFMVGGMPTL 589 Query 548 ELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFV 607 + DSI + K+PL++ +L+ T ++MFLAFGS+VLPIKA LMS L+LGST+G LTW+FV Sbjct 590 QNDSIDSMLGKLPLLMGLLVVVTTLMMFLAFGSLVLPIKAVLMSILSLGSTLGFLTWMFV 649 Query 608 DGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGT 667 DGH NF+ PL APV+ L+IA+VFGLSTDYEVF++SRM+E R G +T ++IR GT Sbjct 650 DGHGGSIFNFSGGPLMAPVLVLVIAVVFGLSTDYEVFVISRMIEERAAGATTVQSIRAGT 709 Query 668 AATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLG 727 A TGRIITAAA+++A VA AF SDLVMMKY++FGLM ALL+DATVVRM LVP+VMKLLG Sbjct 710 ANTGRIITAAAILLACVAAAFATSDLVMMKYVSFGLMFALLIDATVVRMVLVPAVMKLLG 769 Query 728 DDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRP---ARPPVTAGLVAARAAGDPRP 784 DDCWWAP W R++Q IGLGE LP E + +GRP RPP V RAA Sbjct 770 DDCWWAPEWMRKIQHAIGLGETALPAETR----DGRPLASVRPPSA---VPGRAA----- 817 Query 785 PHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLA 844 P L + P S E P ++ A P APS QI P A Sbjct 818 PQ-----LVGAGAPVVPGSLGSAEQRPIPDSAADPTAPSNNERPSGQIRMGNRRPGPPPA 872 Query 845 AAGRSVQSPASTPPPTP 861 +P PP P Sbjct 873 GQPPRPSAPMQRPPQDP 889 >gi|334697758|gb|AEG82555.1| drug exporter of the RND superfamily [Corynebacterium ulcerans 809] Length=872 Score = 600 bits (1548), Expect = 3e-169, Method: Compositional matrix adjust. Identities = 341/787 (44%), Positives = 483/787 (62%), Gaps = 66/787 (8%) Query 1 VFAWWGRTVYRYRFIV-IGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQ 59 +F+ WG YR+R +V + ++V + G+FG+ L + ++Q G+ D GS S QA+ + + Sbjct 1 MFSRWGDFAYRHRRVVPVAIVVFIVAIYGIFGIRLAERMSQEGWDDPGSSSTQAANIEQE 60 Query 60 VYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQD----HPDQVLGWAGYLRAS 115 V+GRD SG +V +F + +D K DE+ ++ D HPDQ+ Y Sbjct 61 VFGRDNSGDVVLLFSS------EDGIAKNKNFDEIKQYLGDLKALHPDQIADVTSYFDNR 114 Query 116 QATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ-RLDGGTVKLAGLQPVAEALT 174 A + + D K F ++ LKGD + T L +++AI +L+ + DG TV++AG VA+AL Sbjct 115 NAQ-LLSKDGKTAFAAVSLKGDHEQT-LKDFRAIKGNLKPKFDGVTVQVAGATAVADALD 172 Query 175 GTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVH 234 +A D +R EV+ALPLVA++L FVFG V+AA +P++VG L I G+LG++ LA F V+ Sbjct 173 SGMAGDIKRAEVVALPLVAILLLFVFGSVVAAFMPLIVGILSILGSLGVLSILAGFAQVN 232 Query 235 YFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVA 294 FAQ VV+L+GLG+AIDYGLF+VSRFREE+ +G D AVR T TAG+TV FSA ++ Sbjct 233 VFAQSVVTLLGLGLAIDYGLFMVSRFREEMDQGRDIRDAVRITTSTAGKTVVFSAAMVAV 292 Query 295 SAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFL 354 + GLL+FPQ FLKS+ Y I++V L+A+LSITVLP+ ILG +D Sbjct 293 ALSGLLVFPQAFLKSVAYGAISAVGLAALLSITVLPSIFAILGTKID------------- 339 Query 355 ANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPV 414 W R R+ + +W KL MKR +V ++I L +P+ Sbjct 340 ----------KWTLRRTNRSA--RTLSDTWWYKLPAWAMKRSKTVVVSLVFLLIALTVPL 387 Query 415 GKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRS 474 ++ GGI+E YLPP + VR+AQ FD+ FP +RT P+ LV+ + T+ Q+ + Sbjct 388 AGITFGGINETYLPPNSDVRKAQSTFDQEFPAFRTEPIKLVVSNA-----TNDQLIKVYQ 442 Query 475 KAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPP 534 +A AI G +R A+KD + VL G+ D + +LRAI P Sbjct 443 QANAITGL-----------TDRFKPSTATKDGTT-VLSAGIAERKDNESVVKQLRAIEVP 490 Query 535 KGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALT 594 +G++V +GGTPA+E++SI LF K+P M + ++ T +LM L FGS++LP KA +M+ L Sbjct 491 EGVSVHIGGTPAMEVESIEALFDKLPWMAIYIVLATFILMSLVFGSMILPAKAIIMTILG 550 Query 595 LGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARE 654 +G+T+GILT +FVDG S NF+ PL +PV+ LI+A+V+GLSTDYEVFLVSRMVEAR+ Sbjct 551 MGATLGILTAMFVDGIGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVFLVSRMVEARD 610 Query 655 RGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVV 714 G ST EAI+ GTA TG IITAAALI+ VV GAF FS++VMMKY+AFG++ ALL DAT++ Sbjct 611 NGESTDEAIKYGTAHTGGIITAAALIMIVVCGAFGFSEIVMMKYIAFGMVVALLFDATII 670 Query 715 RMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLP--------DERKRPVSNGRPAR 766 RM LVP+VM LL +D WWAPRW +R +G P + PV P + Sbjct 671 RMLLVPAVMHLLREDNWWAPRWVKRASEAMGHNSAPEPLPIASPLAESVDTPVRRVEPVQ 730 Query 767 P--PVTA 771 P PV+A Sbjct 731 PRVPVSA 737 >gi|68535213|ref|YP_249918.1| RND superfamily drug exporter [Corynebacterium jeikeium K411] gi|68262812|emb|CAI36300.1| putative drug exporter of the RND superfamily [Corynebacterium jeikeium K411] Length=789 Score = 598 bits (1543), Expect = 1e-168, Method: Compositional matrix adjust. Identities = 344/811 (43%), Positives = 488/811 (61%), Gaps = 65/811 (8%) Query 1 VFAWWGRTVYRYR----FIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVL 56 +F+ WG YR+R ++I ++ L + V GL L ++Q G+ D SQS +A+ + Sbjct 1 MFSSWGDVAYRFRRLIPLVIIAAILVLYV---VAGLKLADRMSQEGWDDPNSQSTKAAQI 57 Query 57 GDQVYGRDRSGHIVAIF--QAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRA 114 +V+GRD +G ++ + P T D+ S + ++ + +++HPD++ G Y Sbjct 58 EQEVFGRDANGDVILMVTGDKPGSATSDEVKQS--ITQQIEQLRKNHPDEIGGVTSYFNR 115 Query 115 SQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLD--GGTVKLAGLQPVAEA 172 A MA D F SI LKG +DD +L N++ I DL+ + G VK+AG V+++ Sbjct 116 GPAA-MANPDGTAAFASIGLKGIEDD-VLINFRKIEDDLRAISAPGVDVKIAGATAVSDS 173 Query 173 LTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGP 232 L +A D R EV ALP V ++L VFGG+IAA +P++VGGL I G++G++ LA F Sbjct 174 LDEGMAGDIHRAEVYALPAVGLLLLIVFGGLIAAFMPLLVGGLSILGSMGVLAILASFTQ 233 Query 233 VHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLI 292 ++ FAQ VV+L+GLG+AIDYGLF+VSRFREE+AEG+DT TAVR T TAG+TV FSA ++ Sbjct 234 INVFAQSVVTLLGLGLAIDYGLFMVSRFREEMAEGHDTRTAVRNTTATAGKTVVFSAAMV 293 Query 293 VASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVP 352 + GL +FPQ FLKS+ + I++V L+A+LS+ VLP+ +LG ++D Sbjct 294 AVALSGLFIFPQAFLKSVAFGAISAVGLAALLSVAVLPSIFAMLGPNID----------- 342 Query 353 FLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLII 412 W + Q + E+VE G WG++ M+ LF IV M+L+ + Sbjct 343 ------------KWSFKKKQSRRRSEQVE-GIWGRIPAFAMRHSKLFTVCIVGGMLLMAV 389 Query 413 PVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADI 472 P+ + LGG++E YLPP+N R QEEF + FP +RT+P+ LVI+ + +A + Sbjct 390 PIAGIKLGGMNETYLPPSNQTRVNQEEFTEKFPQFRTDPIKLVIEGDSKT------VAAV 443 Query 473 RSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAIT 532 +A A+ G P + V +V VL G+ + D + + L I+ Sbjct 444 YKEANAVPGLTAP------------FQVSRPTKDNVTVLSTGIADRKDNDRIVNSLEEIS 491 Query 533 PPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSA 592 G V V GTPALE++SI LF K+P M++ ++ + VLM + FGS+++P KA +M+ Sbjct 492 V-DGANVYVAGTPALEVESIDALFEKLPWMLLYIVLVSFVLMAMIFGSLIIPAKAVIMNI 550 Query 593 LTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEA 652 L G+T+G+LT IFVDGH + NFT PLT+PV+ LIIA+VFGLSTDYEVFLVSRMVEA Sbjct 551 LGTGATLGLLTLIFVDGHGAGMFNFTAGPLTSPVLVLIIAIVFGLSTDYEVFLVSRMVEA 610 Query 653 RERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDAT 712 R RG ST +AIR GTA TG IITAAALI+ VV GAF FS +VMMKY+AFG++ ALLLDAT Sbjct 611 RARGASTDQAIRFGTATTGSIITAAALIMIVVCGAFGFSSIVMMKYIAFGMVIALLLDAT 670 Query 713 VVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAG 772 ++RM LVPSVM LLG D WWAP+W +RL ++G E L R +R VT Sbjct 671 IIRMLLVPSVMHLLGTDNWWAPKWVKRLSEKVGHNE-KLESSPHEAAPAARSSR--VTVA 727 Query 773 LVAARAAGDPRPPHDPTHPLAESPRPARSSP 803 ++ A P P P E+P R+ P Sbjct 728 ELSGVDAIAPVPAQRP----GEAPARQRNLP 754 >gi|300859365|ref|YP_003784348.1| RND superfamily drug exporter [Corynebacterium pseudotuberculosis FRC41] gi|300686819|gb|ADK29741.1| drug exporter of the RND superfamily [Corynebacterium pseudotuberculosis FRC41] gi|302207048|gb|ADL11390.1| Transmembrane transport protein MmpL [Corynebacterium pseudotuberculosis C231] gi|302331608|gb|ADL21802.1| Transmembrane transport protein MmpL [Corynebacterium pseudotuberculosis 1002] gi|308277301|gb|ADO27200.1| Drug exporter of the RND superfamily [Corynebacterium pseudotuberculosis I19] gi|341825739|gb|AEK93260.1| Transmembrane transport protein MmpL [Corynebacterium pseudotuberculosis PAT10] Length=874 Score = 598 bits (1543), Expect = 1e-168, Method: Compositional matrix adjust. Identities = 340/788 (44%), Positives = 487/788 (62%), Gaps = 68/788 (8%) Query 1 VFAWWGRTVYRYRFIV-IGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQ 59 +F+ WG YR+R +V + ++V + G+FG+ L + ++Q G+ D GS S QA+ + + Sbjct 1 MFSRWGDFAYRHRRVVPVAIVVFIVAIYGIFGIRLAERMSQEGWDDPGSSSTQAANIEQE 60 Query 60 VYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQD----HPDQVLGWAGYLRAS 115 V+GRD SG ++ +F + +D K DE+ R+ D HPD + Y Sbjct 61 VFGRDNSGDVILLFSS------EDGIAKNKNFDEIKRYLGDLKALHPDNIADVTSYFDNR 114 Query 116 QATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ-RLDGGTVKLAGLQPVAEALT 174 A + + D K F ++ L+GD + T L +++AI +L+ + DG T+++AG VA+AL Sbjct 115 NAQ-LLSKDGKTAFAAVSLRGDHEQT-LKDFRAIKGNLKPQFDGVTIQVAGATAVADALD 172 Query 175 GTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVH 234 +A D +R E++ALPLVA++L FVFG V+AA +P++VG L I G+LG++ LA F V+ Sbjct 173 SGMAGDIKRAEIVALPLVAILLLFVFGSVVAAFMPLIVGILSILGSLGVLSILAGFTQVN 232 Query 235 YFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVA 294 FAQ VV+L+GLG+AIDYGLF+VSRFREE+ +G D AVR T TAG+TV FSA ++ Sbjct 233 VFAQSVVTLLGLGLAIDYGLFMVSRFREEMDQGRDIADAVRITTSTAGKTVVFSAAMVAV 292 Query 295 SAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFL 354 + GLL+FPQ FLKS+ Y I++V L+A+LSITVLP+ +LG +D Sbjct 293 ALSGLLVFPQAFLKSVAYGAISAVGLAALLSITVLPSIFAMLGTKID------------- 339 Query 355 ANWKISAAYLNWLADRLQRTKTREEVEAG-FWGKLVNRVMKRPVLFAAPIVIIMILLIIP 413 W L+RT AG +W KL MKR IV+++I L +P Sbjct 340 -KWT------------LRRTNRSARTLAGTWWYKLPAWAMKRSKTVVISIVVLLIALTVP 386 Query 414 VGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIR 473 + ++ GGI+E YLPP + VR+AQ FDK FP +RT P+ LV+ + T+ Q+ + Sbjct 387 LAGITFGGINETYLPPNSDVRKAQSTFDKEFPAFRTEPIKLVVSNA-----TNDQLIKVY 441 Query 474 SKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITP 533 +A I G +R A+KD + VL G+ + D + +LRAI Sbjct 442 QQANTITGL-----------TDRFKPSTATKDGTT-VLSAGIADRKDNESVVKQLRAIEV 489 Query 534 PKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSAL 593 P+G+ V +GGTPA+E++SI LF K+P M + ++ T +LM L FGS++LP KA +M+ L Sbjct 490 PEGVNVHIGGTPAMEVESIEALFDKLPWMAIYIVLATFILMSLVFGSMILPAKAIIMTIL 549 Query 594 TLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEAR 653 +G+T+GILT +FVDG S NF+ PL +PV+ LI+A+V+GLSTDYEVFLVSRMVEAR Sbjct 550 GMGATLGILTSMFVDGVGSGLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVFLVSRMVEAR 609 Query 654 ERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATV 713 + G ST EAI+ GTA TG IITAAALI+ VV GAF FS++VMMKY+AFG++ ALL DAT+ Sbjct 610 DNGESTDEAIKYGTAHTGGIITAAALIMIVVCGAFGFSEIVMMKYIAFGMVVALLFDATI 669 Query 714 VRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLP--------DERKRPVSNGRPA 765 +RM LVP+VM LL +D WWAPRW +R +G P + +P+ + PA Sbjct 670 IRMLLVPAVMHLLREDNWWAPRWVKRASEAMGHNAAPEPLPVVSVPVESVDKPMRHAEPA 729 Query 766 RP--PVTA 771 +P PV+A Sbjct 730 QPRVPVSA 737 >gi|337291783|ref|YP_004630804.1| RND superfamily drug exporter [Corynebacterium ulcerans BR-AD22] gi|334700089|gb|AEG84885.1| drug exporter of the RND superfamily [Corynebacterium ulcerans BR-AD22] Length=872 Score = 598 bits (1542), Expect = 2e-168, Method: Compositional matrix adjust. Identities = 339/787 (44%), Positives = 483/787 (62%), Gaps = 66/787 (8%) Query 1 VFAWWGRTVYRYRFIV-IGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQ 59 +F+ WG YR+R +V + ++V + G+FG+ L + ++Q G+ D GS S QA+ + + Sbjct 1 MFSRWGDFAYRHRRVVPVAIVVFIVAIYGIFGIRLAERMSQEGWDDPGSSSTQAANIEQE 60 Query 60 VYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQD----HPDQVLGWAGYLRAS 115 V+GRD SG +V +F + +D K DE+ ++ D HPDQ+ Y Sbjct 61 VFGRDNSGDVVLLFSS------EDGIAKNKNFDEIKQYLGDLKALHPDQIADVTSYFDNR 114 Query 116 QATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQ-RLDGGTVKLAGLQPVAEALT 174 A + + D K F ++ LKGD + T L +++AI +L+ + DG TV++AG VA+AL Sbjct 115 NAQ-LLSKDGKTAFAAVSLKGDHEQT-LKDFRAIKGNLKPKFDGVTVQVAGATAVADALD 172 Query 175 GTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVH 234 +A D +R EV+ALPLVA++L FVFG V+AA +P++VG L I G+LG++ LA F V+ Sbjct 173 SGMAGDIKRAEVVALPLVAILLLFVFGSVVAAFMPLIVGILSILGSLGVLSILAGFAQVN 232 Query 235 YFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVA 294 FAQ VV+L+GLG+AIDYGLF+VSRFREE+ +G D AVR T TAG+TV FSA ++ Sbjct 233 VFAQSVVTLLGLGLAIDYGLFMVSRFREEMDQGRDIRDAVRITTSTAGKTVVFSAAMVAV 292 Query 295 SAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFL 354 + GLL+FPQ FLKS+ Y I++V L+A+LSITVLP+ +LG +D Sbjct 293 ALSGLLVFPQAFLKSVAYGAISAVGLAALLSITVLPSIFAMLGTKID------------- 339 Query 355 ANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPV 414 W R R+ + +W KL MKR +V ++I L +P+ Sbjct 340 ----------KWTLRRTNRSA--RTLSDTWWYKLPAWAMKRSKTVVVSLVFLLIALTVPL 387 Query 415 GKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRS 474 ++ GGI+E YLPP + VR+AQ FD+ FP +RT P+ LV+ + T+ Q+ + Sbjct 388 AGITFGGINETYLPPNSDVRKAQSTFDQEFPAFRTEPIKLVVSNA-----TNDQLIKVYQ 442 Query 475 KAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPP 534 +A AI G +R A+KD + VL G+ D + +LRAI P Sbjct 443 QANAITGL-----------TDRFKPSTATKDGTT-VLSAGIAERKDNESVVKQLRAIKVP 490 Query 535 KGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALT 594 +G++V +GGTPA+E++SI LF K+P M + ++ T +LM L FGS++LP KA +M+ L Sbjct 491 EGVSVHIGGTPAMEVESIEALFDKLPWMAIYIVLATFILMSLVFGSMILPAKAIIMTILG 550 Query 595 LGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARE 654 +G+T+GILT +FVDG S NF+ PL +PV+ LI+A+V+GLSTDYEVFLVSRMVEAR+ Sbjct 551 MGATLGILTAMFVDGIGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVFLVSRMVEARD 610 Query 655 RGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVV 714 G +T EAI+ GTA TG IITAAALI+ VV GAF FS++VMMKY+AFG++ ALL DAT++ Sbjct 611 NGETTDEAIKYGTAHTGGIITAAALIMIVVCGAFGFSEIVMMKYIAFGMVVALLFDATII 670 Query 715 RMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLP--------DERKRPVSNGRPAR 766 RM LVP+VM LL +D WWAPRW +R +G P + PV P + Sbjct 671 RMLLVPAVMHLLREDNWWAPRWVKRASEAMGHNSAPEPLPVASPLVESVDTPVRRVEPVQ 730 Query 767 P--PVTA 771 P PV+A Sbjct 731 PRVPVSA 737 >gi|260578589|ref|ZP_05846499.1| drug exporter of the RND family protein [Corynebacterium jeikeium ATCC 43734] gi|258603304|gb|EEW16571.1| drug exporter of the RND family protein [Corynebacterium jeikeium ATCC 43734] Length=777 Score = 597 bits (1538), Expect = 4e-168, Method: Compositional matrix adjust. Identities = 342/808 (43%), Positives = 487/808 (61%), Gaps = 59/808 (7%) Query 1 VFAWWGRTVYRYRFIV-IGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQ 59 +F+ WG YR+R ++ + ++ A+ + V GL L ++Q G+ D SQS +A+ + + Sbjct 1 MFSSWGDVAYRFRRLIPLVIIAAILVLYVVAGLKLADRMSQEGWDDPNSQSTKAAQIEQE 60 Query 60 VYGRDRSGHIVAIF--QAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQA 117 V+GRD +G ++ + P T D+ + + ++ + ++DHPD++ G Y A Sbjct 61 VFGRDANGDVILMVTGDKPGSATSDEV--KQSITQQIEQLRKDHPDEIGGVTSYFNRGPA 118 Query 118 TGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLD--GGTVKLAGLQPVAEALTG 175 MA D F SI L+G +DD +L N++ I DL+ + G VK+AG V+++L Sbjct 119 -AMANPDGTAAFASIGLQGIEDD-VLINFRKIEDDLRAISAPGVDVKIAGATAVSDSLDE 176 Query 176 TIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHY 235 +A D R E+ ALP V ++L VFGG+IAA +P++VGGL I G++G++ LA F ++ Sbjct 177 GMAGDIHRAEIYALPAVGLLLLIVFGGLIAAFMPLLVGGLSILGSMGVLAILASFTQINV 236 Query 236 FAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVAS 295 FAQ VV+L+GLG+AIDYGLF+VSRFREE+AEG+DT TAVR T TAG+TV FSA ++ + Sbjct 237 FAQSVVTLLGLGLAIDYGLFMVSRFREEMAEGHDTRTAVRNTTATAGKTVVFSAAMVAVA 296 Query 296 AIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLA 355 GL +FPQ FLKS+ + I++V L+A+LS+ VLP+ +LG ++D Sbjct 297 LSGLFIFPQAFLKSVAFGAISAVGLAALLSVAVLPSIFAMLGPNID-------------- 342 Query 356 NWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVG 415 W + +RT+ R E G WG++ M+ LF IV M+L+ +P+ Sbjct 343 KWSF----------KKKRTRRRSEQVEGIWGRIPAFAMRHSKLFTVVIVGGMLLMAVPIA 392 Query 416 KLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSK 475 + LGG++E YLPP+N R QEEF + FP +RT+P+ LVI+ + +A + + Sbjct 393 GIKLGGMNETYLPPSNQTRVNQEEFTEKFPQFRTDPIKLVIEGDSKT------VAAVYKE 446 Query 476 AMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPK 535 A AI G P + V V VL G+ + D + + L I Sbjct 447 ANAIPGLTAP------------FQVSRPTKDDVTVLSTGIADRDDNDRIVNTLEDINV-D 493 Query 536 GITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTL 595 G V V GTPALE++SI LF K+P M++ ++ + VLM + FGS+++P KA +M+ L Sbjct 494 GANVYVAGTPALEVESIDALFEKLPWMLLYIVLVSFVLMAMIFGSLIIPAKAVIMNILGT 553 Query 596 GSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARER 655 G+T+G+LT IFVDGH + NFT PLT+PV+ LIIA+VFGLSTDYEVFLVSRMVEAR R Sbjct 554 GATLGLLTLIFVDGHGADMFNFTAGPLTSPVLVLIIAIVFGLSTDYEVFLVSRMVEARAR 613 Query 656 GMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVR 715 G ST +AIR GTA TG IITAAALI+ VV GAF FS +VMMKY+AFG++ ALLLDAT++R Sbjct 614 GASTDQAIRFGTATTGSIITAAALIMIVVCGAFGFSSIVMMKYIAFGMVIALLLDATIIR 673 Query 716 MFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVA 775 M LVPSVM LLG D WWAP+W +RL ++G E L R +R VT ++ Sbjct 674 MLLVPSVMHLLGTDNWWAPKWVKRLSEKVGHNE-KLESSPHEAAPAARSSR--VTVAELS 730 Query 776 ARAAGDPRPPHDPTHPLAESPRPARSSP 803 A P P P E+P R+ P Sbjct 731 GVDAIAPVPAQRP----GEAPARQRNLP 754 >gi|336325108|ref|YP_004605074.1| RND superfamily membrane protein [Corynebacterium resistens DSM 45100] gi|336101090|gb|AEI08910.1| membrane protein of the RND superfamily [Corynebacterium resistens DSM 45100] Length=846 Score = 596 bits (1536), Expect = 8e-168, Method: Compositional matrix adjust. Identities = 353/842 (42%), Positives = 503/842 (60%), Gaps = 88/842 (10%) Query 1 VFAWWGRTVYRYR----FIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVL 56 +F+ WG YR+R F++I +VAL VFGL LG+ ++Q G+ D SQS +A+ + Sbjct 1 MFSTWGDVAYRFRRVIPFVIIVAIVALY---AVFGLKLGERMSQEGWDDPHSQSTRAAQI 57 Query 57 GDQVYGRD-RSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLG----WAGY 111 V+GRD RS I+ + G V+D K++ ++L + ++ HPDQV + G Sbjct 58 EQDVFGRDARSDVIILVTGNGPGAAVND-GVKKQMAEQLKKLKESHPDQVAAISSVYTGG 116 Query 112 LRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLD--GGTVKLAGLQPV 169 RA +A D TF S+ LKG ++D +L NY+ I +L +++ G V++AG V Sbjct 117 PRA-----LAKEDGSATFTSVSLKGVNED-VLKNYRVIEDELHQINAPGVKVEIAGATAV 170 Query 170 AEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAI 229 + AL +A D R E+ ALP V V+L VFGGVIAA +P++VG L I G++G++ LA Sbjct 171 SGALDKGMAEDISRAELYALPAVGVLLLLVFGGVIAACMPLLVGVLSILGSMGVLAILAD 230 Query 230 FGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSA 289 ++ FAQ VV+L+GLG+AIDYGLF+VSRFREE+AEG D TAVR T TAG+TV FSA Sbjct 231 ATQINVFAQSVVTLLGLGLAIDYGLFMVSRFREELAEGNDVPTAVRNTTATAGKTVVFSA 290 Query 290 VLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLF 349 ++ + GLL+FPQ FLKS+ + +++V L+A+LS+ VLP+ G+LGK++D +R Sbjct 291 AMVAVALSGLLIFPQAFLKSVAFGAMSAVGLAALLSVAVLPSIFGLLGKNIDKWSIR--- 347 Query 350 RVPFLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMIL 409 +++++R EV GFWGK+ M+ +V+ ++ Sbjct 348 ----------------------RKSQSRTEVVNGFWGKVPAFAMRHSKKVTFLLVVGLLA 385 Query 410 LIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQI 469 L +P+ + LGGI+E YLPP+N R AQ FD+ FP +RTNP+ LVI+ A + Sbjct 386 LTVPIAGIKLGGINETYLPPSNETRVAQSHFDEQFPQFRTNPIKLVIKGDG------AAV 439 Query 470 ADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASK---KLT 526 + +A + G P + V V VL G+ N D S+ KL Sbjct 440 GQVFQQANQLEGLTAP------------FQVTQPTKDGVTVLGTGIQNRDDYSRIVHKLE 487 Query 527 ELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIK 586 +L+ +G VLV GTPALE++SI LF K+P M++ ++ + +LM L FGS+++P K Sbjct 488 DLKV----EGAEVLVAGTPALEVESISALFEKLPWMLIYIVAVSFILMALIFGSLIIPAK 543 Query 587 ATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLV 646 A +M+ L G+T+G+LT +FVDG + N+T PL +P++ LI+A++FGLSTDYEVFLV Sbjct 544 AVIMNILGTGATLGVLTLLFVDGVGADLFNYTAGPLMSPILVLIVAIIFGLSTDYEVFLV 603 Query 647 SRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAA 706 SRMVEAR RG ST +AIR GTA TG IITAAALI+ VV GAF FS +VMMKY+AFG++ A Sbjct 604 SRMVEARARGASTDQAIRFGTATTGSIITAAALIMIVVCGAFGFSSIVMMKYIAFGMVIA 663 Query 707 LLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPAR 766 L+LDATV+RM LVP+VM LL +D WWAP W ++L ++G +E+ S P + Sbjct 664 LILDATVIRMLLVPAVMHLLREDSWWAPGWVKKLSEKVG------HNEQLSGTSAAHPMQ 717 Query 767 PPVTAGLVAARAAGDPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGAS 826 PV AG A A G P+ A P R++ A P A AP SGA Sbjct 718 -PVPAGPAAGLARGGVEMEEKPS---AVQPEAGRNATAEQP-------AHNAPPQDSGAR 766 Query 827 TT 828 +T Sbjct 767 ST 768 Lambda K H 0.321 0.137 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 2345775499770 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40