BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0232 Length=229 Score E Sequences producing significant alignments: (Bits) Value gi|15607373|ref|NP_214746.1| TetR/ACRR family transcriptional re... 454 4e-126 gi|183980517|ref|YP_001848808.1| TetR family transcriptional reg... 367 7e-100 gi|118616870|ref|YP_905202.1| TetR family transcriptional regula... 366 2e-99 gi|254823271|ref|ZP_05228272.1| transcriptional regulator, TetR ... 357 1e-96 gi|118463620|ref|YP_884059.1| TetR family transcriptional regula... 356 1e-96 gi|41409769|ref|NP_962605.1| hypothetical protein MAP3671 [Mycob... 355 3e-96 gi|296167462|ref|ZP_06849861.1| TetR family transcriptional regu... 350 1e-94 gi|240168451|ref|ZP_04747110.1| TetR family transcriptional regu... 337 1e-90 gi|126437013|ref|YP_001072704.1| TetR family transcriptional reg... 332 2e-89 gi|108801179|ref|YP_641376.1| TetR family transcriptional regula... 327 6e-88 gi|342859300|ref|ZP_08715954.1| TetR family transcriptional regu... 327 7e-88 gi|333988854|ref|YP_004521468.1| TetR family transcriptional reg... 325 4e-87 gi|145223647|ref|YP_001134325.1| TetR family transcriptional reg... 316 2e-84 gi|120404439|ref|YP_954268.1| TetR family transcriptional regula... 307 8e-82 gi|328456941|gb|AEB02364.1| transcriptional regulator, tetR/acrR... 254 1e-65 gi|297632712|ref|ZP_06950492.1| transcriptional regulator, tetR/... 245 3e-63 gi|269128033|ref|YP_003301403.1| TetR family transcriptional reg... 187 1e-45 gi|302526615|ref|ZP_07278957.1| predicted protein [Streptomyces ... 174 8e-42 gi|160334156|gb|ABX24480.1| transcriptional regulatory protein [... 167 1e-39 gi|326328694|ref|ZP_08195033.1| transcriptional regulator, TetR ... 158 5e-37 gi|328456942|gb|AEB02365.1| transcriptional regulator, tetR/acrR... 134 1e-29 gi|328953115|ref|YP_004370449.1| TetR family transcriptional reg... 103 2e-20 gi|150392351|ref|YP_001322400.1| TetR family transcriptional reg... 92.4 5e-17 gi|220933160|ref|YP_002510068.1| TetR family transcriptional reg... 81.6 7e-14 gi|310657336|ref|YP_003935057.1| regulatory protein, tetr [Clost... 80.1 2e-13 gi|116750511|ref|YP_847198.1| TetR family transcriptional regula... 79.7 3e-13 gi|296132337|ref|YP_003639584.1| transcriptional regulator, TetR... 79.7 3e-13 gi|220931220|ref|YP_002508128.1| TetR family transcriptional reg... 77.4 1e-12 gi|332702866|ref|ZP_08422954.1| regulatory protein TetR [Desulfo... 73.6 2e-11 gi|220931221|ref|YP_002508129.1| TetR family transcriptional reg... 71.6 8e-11 gi|320449430|ref|YP_004201526.1| transcriptional regulator [Ther... 70.9 1e-10 gi|149923117|ref|ZP_01911532.1| hypothetical protein PPSIR1_1356... 70.1 3e-10 gi|335038847|ref|ZP_08532049.1| transcriptional regulator, TetR ... 69.7 3e-10 gi|335427843|ref|ZP_08554763.1| TetR family transcriptional regu... 69.7 3e-10 gi|118444554|ref|YP_877628.1| AcrR family transcriptional regula... 69.3 4e-10 gi|212639401|ref|YP_002315921.1| TetR/AcrR family transcriptiona... 68.6 6e-10 gi|168185353|ref|ZP_02619988.1| putative transcriptional regulat... 67.8 1e-09 gi|335351151|gb|EGM52645.1| TetR/AcrR family transcriptional reg... 67.8 1e-09 gi|163848264|ref|YP_001636308.1| regulatory protein TetR [Chloro... 67.4 1e-09 gi|334307407|gb|EGL98393.1| transcriptional regulator, TetR fami... 67.4 2e-09 gi|312142674|ref|YP_003994120.1| TetR family transcriptional reg... 67.4 2e-09 gi|219670673|ref|YP_002461108.1| TetR family transcriptional reg... 67.4 2e-09 gi|156740970|ref|YP_001431099.1| TetR family transcriptional reg... 67.0 2e-09 gi|218294628|ref|ZP_03495482.1| transcriptional regulator, TetR ... 67.0 2e-09 gi|225181254|ref|ZP_03734699.1| transcriptional regulator, TetR ... 67.0 2e-09 gi|317132259|ref|YP_004091573.1| regulatory protein TetR [Ethano... 67.0 2e-09 gi|222100510|ref|YP_002535078.1| Transcriptional regulator, TetR... 66.6 2e-09 gi|336428058|ref|ZP_08608046.1| hypothetical protein HMPREF0994_... 66.6 3e-09 gi|227891870|ref|ZP_04009675.1| TetR/AcrR family transcriptional... 66.2 3e-09 gi|253681556|ref|ZP_04862353.1| transcriptional regulator, TetR ... 66.2 3e-09 >gi|15607373|ref|NP_214746.1| TetR/ACRR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15839612|ref|NP_334649.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31791409|ref|NP_853902.1| TetR/ACRR family transcriptional regulator [Mycobacterium bovis AF2122/97] 78 more sequence titles Length=229 Score = 454 bits (1169), Expect = 4e-126, Method: Compositional matrix adjust. Identities = 229/229 (100%), Positives = 229/229 (100%), Gaps = 0/229 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV Sbjct 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR Sbjct 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT Sbjct 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 >gi|183980517|ref|YP_001848808.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183173843|gb|ACC38953.1| transcriptional regulatory protein (probably TetR/AcrR-family) [Mycobacterium marinum M] Length=223 Score = 367 bits (942), Expect = 7e-100, Method: Compositional matrix adjust. Identities = 193/211 (92%), Positives = 205/211 (98%), Gaps = 0/211 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAA+VEAAEAEFGAHGFS+GSLNVIARRA VAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAIVEAAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A+IADIASQRVR+++E LIRELD +RPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV Sbjct 61 AYIADIASQRVRTHIEGLIRELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTDARISVRSV+HRHYL+VLRPLVRDA ARGDLRADSDT AL+SLLL+IFPHLALAPYMR Sbjct 121 DTDARISVRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLMIFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAF 211 GLDPILGLDEPTPEQPALAVRRLVAVL AA+ Sbjct 181 GLDPILGLDEPTPEQPALAVRRLVAVLTAAY 211 >gi|118616870|ref|YP_905202.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118568980|gb|ABL03731.1| transcriptional regulatory protein (probably TetR/AcrR-family) [Mycobacterium ulcerans Agy99] Length=223 Score = 366 bits (939), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 192/211 (91%), Positives = 205/211 (98%), Gaps = 0/211 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAA+VEAAEAEFGAHGFS+GSLNVIARRA VAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAIVEAAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A+IADIA+QRVR+++E LIRELD +RPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV Sbjct 61 AYIADIANQRVRTHIEGLIRELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTDARISVRSV+HRHYL+VLRPLVRDA ARGDLRADSDT AL+SLLL+IFPHLALAPYMR Sbjct 121 DTDARISVRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLMIFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAF 211 GLDPILGLDEPTPEQPALAVRRLVAVL AA+ Sbjct 181 GLDPILGLDEPTPEQPALAVRRLVAVLTAAY 211 >gi|254823271|ref|ZP_05228272.1| transcriptional regulator, TetR family protein [Mycobacterium intracellulare ATCC 13950] Length=228 Score = 357 bits (915), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 197/229 (87%), Positives = 214/229 (94%), Gaps = 1/229 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAA++EAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAIIEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFIADIASQRVR+YME IRELDP+RPFFEFLTD LD WVAYFA+HP ERALHAAATLEV Sbjct 61 AFIADIASQRVRAYMEGRIRELDPSRPFFEFLTDWLDAWVAYFADHPHERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DT+AR+SV++V+HRHYL+V+RPLVRDAH RGDLRA+SDT AL+SLLLLIFPHLALAPYMR Sbjct 121 DTEARVSVQNVIHRHYLEVMRPLVRDAHLRGDLRAESDTDALLSLLLLIFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 GLDPILGLDEPTPEQPALAVRRLV VLAAAF A + NSA RSEE++ Sbjct 181 GLDPILGLDEPTPEQPALAVRRLVGVLAAAFSADS-SVNSAPQRSEEVS 228 >gi|118463620|ref|YP_884059.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777376|ref|ZP_05218892.1| transcriptional regulator, TetR family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118164907|gb|ABK65804.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] Length=227 Score = 356 bits (913), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 198/229 (87%), Positives = 214/229 (94%), Gaps = 2/229 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAA++EAAE+EFGAHGFSRGSLNVIAR+AGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAIIEAAESEFGAHGFSRGSLNVIARKAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFIADI SQRVR Y+E LIRELDP RPFFEFLTDLLDGWVAYFA+HP ERALHAAATLEV Sbjct 61 AFIADIGSQRVRGYIEQLIRELDPTRPFFEFLTDLLDGWVAYFADHPHERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DT+ARISV++V+HRHYL+VLRPLVRDA RGDLRADSDT AL+SLLLLIFPHLALAPYMR Sbjct 121 DTEARISVQNVIHRHYLEVLRPLVRDARLRGDLRADSDTDALLSLLLLIFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 GLDP+LGLDEPTPEQPALAVRRLVAVLAAAF + PA + A RSEE+T Sbjct 181 GLDPVLGLDEPTPEQPALAVRRLVAVLAAAF-SPAPA-HFATPRSEEVT 227 >gi|41409769|ref|NP_962605.1| hypothetical protein MAP3671 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398601|gb|AAS06221.1| hypothetical protein MAP_3671 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460102|gb|EGO39010.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=227 Score = 355 bits (910), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 198/229 (87%), Positives = 214/229 (94%), Gaps = 2/229 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAA++EAAE+EFGAHGFSRGSLNVIAR+AGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAIIEAAESEFGAHGFSRGSLNVIARKAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFIADI SQRVR Y+E LIRELDP RPFFEFLTDLLDGWVAYFA+HP ERALHAAATLEV Sbjct 61 AFIADIGSQRVRGYIEQLIRELDPARPFFEFLTDLLDGWVAYFADHPHERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DT+ARISV++V+HRHYL+VLRPLVRDA RGDLRADSDT AL+SLLLLIFPHLALAPYMR Sbjct 121 DTEARISVQNVIHRHYLEVLRPLVRDARLRGDLRADSDTDALLSLLLLIFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 GLDP+LGLDEPTPEQPALAVRRLVAVLAAAF + PA + A RSEE+T Sbjct 181 GLDPVLGLDEPTPEQPALAVRRLVAVLAAAF-SPAPA-HFATPRSEEVT 227 >gi|296167462|ref|ZP_06849861.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897210|gb|EFG76817.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=228 Score = 350 bits (897), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 190/208 (92%), Positives = 202/208 (98%), Gaps = 0/208 (0%) Query 4 VTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFI 63 +TWARVDPARRAA++EAAE EFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFI Sbjct 1 MTWARVDPARRAAIIEAAEHEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFI 60 Query 64 ADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTD 123 ADI SQRVRSY+E+LIRELDP+RPFFEFLTDLLD WVAYFAEHPRERALHAAA+LEVDTD Sbjct 61 ADIGSQRVRSYIEELIRELDPSRPFFEFLTDLLDAWVAYFAEHPRERALHAAASLEVDTD 120 Query 124 ARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLD 183 AR+SVRSV+HRHYL+VLRPLVRDA RGDLRADSDT AL+SLLLLIFPHLALAPYMRGLD Sbjct 121 ARVSVRSVIHRHYLEVLRPLVRDAQVRGDLRADSDTDALLSLLLLIFPHLALAPYMRGLD 180 Query 184 PILGLDEPTPEQPALAVRRLVAVLAAAF 211 PILGLDEP+PEQPALAVRRLVAVLAAAF Sbjct 181 PILGLDEPSPEQPALAVRRLVAVLAAAF 208 >gi|240168451|ref|ZP_04747110.1| TetR family transcriptional regulator [Mycobacterium kansasii ATCC 12478] Length=223 Score = 337 bits (863), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 191/211 (91%), Positives = 202/211 (96%), Gaps = 0/211 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAA+VEAAEAEFGAHGFS GSLNVIARRA VAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAIVEAAEAEFGAHGFSNGSLNVIARRARVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A+IADI SQRVRSYME+LIRELDP+RPFFEFLTDLLDGWVAY+AEHPRERALHAAATLEV Sbjct 61 AYIADIGSQRVRSYMENLIRELDPSRPFFEFLTDLLDGWVAYYAEHPRERALHAAATLEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTDARISVRSV+HRHYL+VLRPLVRDA RG LRAD+D L+SLLLL+FPHLALAPYMR Sbjct 121 DTDARISVRSVIHRHYLEVLRPLVRDAQNRGHLRADADIDVLLSLLLLLFPHLALAPYMR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAF 211 GLDP+LGLDEPTPEQPALAVRRLVAVLAAAF Sbjct 181 GLDPVLGLDEPTPEQPALAVRRLVAVLAAAF 211 >gi|126437013|ref|YP_001072704.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|126236813|gb|ABO00214.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=229 Score = 332 bits (852), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 179/229 (79%), Positives = 199/229 (87%), Gaps = 1/229 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWAR+D RRAAVV AAEAEF AHGFS GSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARLDGERRAAVVAAAEAEFAAHGFSHGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFI D+ASQRVRSYME IRELD +RPFF FL DLLD WVAYFAEHPRER+LHAAA+ EV Sbjct 61 AFITDVASQRVRSYMETQIRELDASRPFFPFLVDLLDAWVAYFAEHPRERSLHAAASFEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 +TDAR+SVR+V+HRHYL+VLRPLV DA ARGDLR D+DT L+SLLL+I PHLALAPY+R Sbjct 121 ETDARVSVRAVVHRHYLEVLRPLVHDARARGDLRDDADTETLVSLLLMILPHLALAPYVR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 GLDPILGLDE +PEQPALAVRR VAVL+AAF P S +T ++E+T Sbjct 181 GLDPILGLDELSPEQPALAVRRYVAVLSAAFQTV-PVQPSPETSAQEVT 228 >gi|108801179|ref|YP_641376.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119870311|ref|YP_940263.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|108771598|gb|ABG10320.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119696400|gb|ABL93473.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] Length=229 Score = 327 bits (839), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 177/229 (78%), Positives = 198/229 (87%), Gaps = 1/229 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWAR+D RRAAVV AAEAEF AHGFS GSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARLDGERRAAVVAAAEAEFAAHGFSHGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFI D+ASQRVRSYME IRELD +RPFF FL DLLD WVAYFAEHPRER+LHAAA+ EV Sbjct 61 AFITDVASQRVRSYMETQIRELDASRPFFPFLVDLLDAWVAYFAEHPRERSLHAAASFEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 +TDAR+SVR+V+HRHYL+VLRPLV DA ARGDLR D+DT L+SLLL+I PHLALAPY+R Sbjct 121 ETDARVSVRAVVHRHYLEVLRPLVHDARARGDLRDDADTETLVSLLLMILPHLALAPYVR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT 229 GLDPILGLDE +PEQPALAVRR VAVL+AAF P + + ++E+T Sbjct 181 GLDPILGLDELSPEQPALAVRRYVAVLSAAFQTV-PVQPTRDSIAQEVT 228 >gi|342859300|ref|ZP_08715954.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342133541|gb|EGT86744.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=223 Score = 327 bits (839), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 189/223 (85%), Positives = 207/223 (93%), Gaps = 2/223 (0%) Query 9 VDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIAS 68 +DPARRAA++EAAE+EFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADI S Sbjct 1 MDPARRAAIIEAAESEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIGS 60 Query 69 QRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARISV 128 QRVR+YMED IRELDP+RPFF+FLTD LD WVAYFA+HP ERALHAAATLEVDT+AR+SV Sbjct 61 QRVRAYMEDRIRELDPSRPFFDFLTDWLDAWVAYFADHPHERALHAAATLEVDTEARVSV 120 Query 129 RSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDPILGL 188 + V+HRHYL+V+RPLVRDAH RGDLRADSDT AL+SLLLLIFPHLALAPYMRGLDPILGL Sbjct 121 QHVIHRHYLEVMRPLVRDAHVRGDLRADSDTDALLSLLLLIFPHLALAPYMRGLDPILGL 180 Query 189 DEPTPEQPALAVRRLVAVLAAAFDA--QHPATNSAQTRSEEIT 229 DEPTPEQPALAVRRLVAVLAAAF A + P +SA RSEE+T Sbjct 181 DEPTPEQPALAVRRLVAVLAAAFSAAPKTPPISSAPKRSEEVT 223 >gi|333988854|ref|YP_004521468.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333484822|gb|AEF34214.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] Length=227 Score = 325 bits (832), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 177/214 (83%), Positives = 196/214 (92%), Gaps = 0/214 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTW RVDPARRAAV+EAAEAEF A GFS GSLNVIARRA VAKGSLFQYFADK DLY Sbjct 1 MPTVTWGRVDPARRAAVLEAAEAEFSARGFSHGSLNVIARRAEVAKGSLFQYFADKADLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AF+AD A QRVRSYME I +LDP+RPFFEFLTD+LD WVAYFA+HPRERALHAAA++E+ Sbjct 61 AFVADTAGQRVRSYMERRIVDLDPSRPFFEFLTDMLDVWVAYFADHPRERALHAAASMEI 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTDARISVR+V+HRHYL+VLRPLV DA ARGDLRAD+DTGAL+SLLLLI PHLALAPY+R Sbjct 121 DTDARISVRTVVHRHYLEVLRPLVDDAQARGDLRADADTGALLSLLLLIVPHLALAPYLR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQ 214 G+DP+LGLDE TPEQPALA+RRLVAVLAAAF + Sbjct 181 GIDPVLGLDEHTPEQPALAIRRLVAVLAAAFGGE 214 >gi|145223647|ref|YP_001134325.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|315443973|ref|YP_004076852.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|145216133|gb|ABP45537.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] gi|315262276|gb|ADT99017.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=230 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 168/227 (75%), Positives = 188/227 (83%), Gaps = 1/227 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTW+R+ RRAAVV AAE EF AHGFS GSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWSRLGADRRAAVVAAAETEFAAHGFSGGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A I ++ SQRVR +MED IR LDP RPFFEFLTDLLD WVAYFAEHP++RALHAAA+ EV Sbjct 61 AHITEVGSQRVRRHMEDQIRILDPGRPFFEFLTDLLDVWVAYFAEHPQDRALHAAASFEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTDAR+SVR+V+HRHYL VLRPLV A RGDLR D+DT ++SLLL+I PHLALAPY+R Sbjct 121 DTDARVSVRAVVHRHYLQVLRPLVHAAGTRGDLRPDADTDTMLSLLLMILPHLALAPYVR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEE 227 G+DP+LGLDE PEQPAL VRR VAVLAAAF A P Q + +E Sbjct 181 GMDPVLGLDEIAPEQPALVVRRYVAVLAAAF-ADTPTPGPRQPQPKE 226 >gi|120404439|ref|YP_954268.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119957257|gb|ABM14262.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=228 Score = 307 bits (787), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 170/214 (80%), Positives = 189/214 (89%), Gaps = 0/214 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTW+R++ RRAAVV AAEAEF AHGFS+GSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWSRLNEDRRAAVVAAAEAEFAAHGFSQGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A I D+ SQRVR YMED IR LDP RPFF FLTDLLD WVAYFAEHPRER+LHAAA+ EV Sbjct 61 AHITDVGSQRVRCYMEDQIRVLDPTRPFFAFLTDLLDVWVAYFAEHPRERSLHAAASFEV 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 DTD R+SVR+V+HRHYL+VLRPLVRDA RGDLR D+DT AL+SLLL+I PHLALAPY+R Sbjct 121 DTDTRVSVRAVIHRHYLEVLRPLVRDARGRGDLRPDADTDALLSLLLMILPHLALAPYVR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQ 214 G+DP+LGLDE +P+QPAL VRR VAVLAAAF Q Sbjct 181 GMDPVLGLDELSPDQPALVVRRYVAVLAAAFAPQ 214 >gi|328456941|gb|AEB02364.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis KZN 4207] Length=193 Score = 254 bits (648), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 126/127 (99%), Positives = 126/127 (99%), Gaps = 0/127 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY Sbjct 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV Sbjct 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 Query 121 DTDARIS 127 DTDARI Sbjct 121 DTDARIK 127 >gi|297632712|ref|ZP_06950492.1| transcriptional regulator, tetR/acrR-family protein [Mycobacterium tuberculosis KZN 4207] Length=190 Score = 245 bits (626), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 122/124 (99%), Positives = 123/124 (99%), Gaps = 0/124 (0%) Query 4 VTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFI 63 +TWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFI Sbjct 1 MTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFI 60 Query 64 ADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTD 123 ADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTD Sbjct 61 ADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTD 120 Query 124 ARIS 127 ARI Sbjct 121 ARIK 124 >gi|269128033|ref|YP_003301403.1| TetR family transcriptional regulator [Thermomonospora curvata DSM 43183] gi|268312991|gb|ACY99365.1| transcriptional regulator, TetR family [Thermomonospora curvata DSM 43183] Length=218 Score = 187 bits (474), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 101/211 (48%), Positives = 134/211 (64%), Gaps = 0/211 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT TW R+D A+R V+ AA EFG +G+S GSLN IAR AG+AKGSLFQYF DK + + Sbjct 1 MPTSTWFRLDVAKRNRVLHAAMREFGENGYSTGSLNTIAREAGIAKGSLFQYFTDKLEFF 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A++ D S+R+R ME I +D ++P E+L D W Y A+HP ER + AA E+ Sbjct 61 AYVCDETSRRIREEMERRIAAIDLDQPVDEWLFDAFCEWTEYMADHPLERGVTAATNFEL 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 D + R VR ++HYL V+ P++ RGD+R D+D L SLLL+ P LALAPY Sbjct 121 DNNVRAVVRDTANQHYLQVIHPVLELWKERGDIRPDADLDILASLLLMTLPFLALAPYYD 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAF 211 GLDP+L + TPEQ +RRL+A + F Sbjct 181 GLDPVLDMRGRTPEQQRPIIRRLIAGITPLF 211 >gi|302526615|ref|ZP_07278957.1| predicted protein [Streptomyces sp. AA4] gi|302435510|gb|EFL07326.1| predicted protein [Streptomyces sp. AA4] Length=213 Score = 174 bits (442), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 119/211 (57%), Positives = 143/211 (68%), Gaps = 0/211 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT TW R+ RRAAV+ AAEAEF A GFS GSLN I R AGV+KGSLFQYFADK D+Y Sbjct 1 MPTGTWERLPEKRRAAVLAAAEAEFAARGFSGGSLNTICREAGVSKGSLFQYFADKADMY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 +A++AS R+R+ ME I EL + F L LLD WV YF +HP ERA+ AAA LE Sbjct 61 VHLAELASVRIRAAMEAEIAELPWDNDFAGALDRLLDAWVRYFYDHPLERAMTAAANLEP 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 D AR VR ++RHYL VLRPL+ A A G LRAD+D ++SLLLL+ PHLALAP++ Sbjct 121 DPTARTPVREAVNRHYLAVLRPLIERAVAAGQLRADTDVEIVLSLLLLVLPHLALAPHVE 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAF 211 GLDP+LGL E A RR+ VL + Sbjct 181 GLDPLLGLVEGDSAHAAATARRMTGVLLGPY 211 >gi|160334156|gb|ABX24480.1| transcriptional regulatory protein [Streptomyces cacaoi subsp. asoensis] Length=217 Score = 167 bits (422), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 103/211 (49%), Positives = 135/211 (64%), Gaps = 0/211 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT TW R+ PARR V+ AA EFG HG+S GSLNVIAR AGVAKGSLFQYF+ K DL+ Sbjct 1 MPTPTWDRLSPARRERVLVAAMDEFGTHGYSTGSLNVIAREAGVAKGSLFQYFSGKLDLF 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 A++A+ S RV ++M+ + D + F +L D L+ W+ YFA P ER + AA +E+ Sbjct 61 AYVAEQTSLRVYAHMQPWLDGYDESGDFRTYLVDALEAWLDYFAGQPLERGVTAATNMEM 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 D R +VR+ ++ YL LRPL+ A A GDLR D+D AL+S+LL+ PHLAL P++ Sbjct 121 DPAVRDAVRAPVNAVYLAGLRPLLERAVATGDLRKDADLDALLSILLVFLPHLALLPHLS 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAF 211 G D L L P+ + RLV L A F Sbjct 181 GGDGPLPLTSVDPQARRANLERLVTPLLADF 211 >gi|326328694|ref|ZP_08195033.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium Broad-1] gi|325953504|gb|EGD45505.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium Broad-1] Length=220 Score = 158 bits (400), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 86/214 (41%), Positives = 124/214 (58%), Gaps = 0/214 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT TW R+ A+R AV AAE EFG G++ SLN I R AG++KGSLFQYF DK DL+ Sbjct 1 MPTPTWERLPEAKRDAVRRAAEEEFGVRGYNAASLNTICREAGISKGSLFQYFPDKSDLF 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 + AS +R ME +L + + L+D W+ YF + PR R + +A LE Sbjct 61 VHLIARASHDIRVAMEAASVDLPWMTDYIGSVNLLMDAWIDYFYDQPRHRQMLVSANLEH 120 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMR 180 + A +VR ++ YL+V+ ++ A G LR D+D AL++ ++++ PH+AL P++R Sbjct 121 NPSALAAVREAVYVDYLEVIGGMIDLGIAIGALRKDTDRDALVAAIIMLLPHIALGPHVR 180 Query 181 GLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQ 214 GLDP+LGL RRL+ VL + Q Sbjct 181 GLDPLLGLAGSDRTHAMSVGRRLIQVLMGQYVTQ 214 >gi|328456942|gb|AEB02365.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis KZN 4207] Length=67 Score = 134 bits (336), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 67/67 (100%), Positives = 67/67 (100%), Gaps = 0/67 (0%) Query 163 MSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQ 222 MSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQ Sbjct 1 MSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQ 60 Query 223 TRSEEIT 229 TRSEEIT Sbjct 61 TRSEEIT 67 >gi|328953115|ref|YP_004370449.1| TetR family transcriptional regulator [Desulfobacca acetoxidans DSM 11109] gi|328453439|gb|AEB09268.1| transcriptional regulator, TetR family [Desulfobacca acetoxidans DSM 11109] Length=221 Score = 103 bits (256), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/210 (33%), Positives = 104/210 (50%), Gaps = 4/210 (1%) Query 1 MPTV---TWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKR 57 MP + T+ + A++A +++AA EF + G+ + SLNVI R+G+AKGSL+QYF DK Sbjct 1 MPEIVRPTFLNLPEAKQARIIDAALEEFASKGYPQASLNVIVARSGIAKGSLYQYFTDKS 60 Query 58 DLYAFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAAT 117 ++ +I D A VR + ++E FF L L VA+ EHPR ++ Sbjct 61 GVFLYIFDFAISFVRRILVQ-VKESTLGEDFFTRLEKSLLAGVAFIKEHPRIYGIYLKIL 119 Query 118 LEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAP 177 + R + + + D L+ L+R ARG+LR LL + A Sbjct 120 FDQQVPQRQELLRAVRQFSADYLQSLLRQGMARGELRPGLPQQTTTFLLDALLDRFLQAV 179 Query 178 YMRGLDPILGLDEPTPEQPALAVRRLVAVL 207 + D LGLD+ T E+ VR LV+VL Sbjct 180 SVPAFDVALGLDQATEEELGQRVRELVSVL 209 >gi|150392351|ref|YP_001322400.1| TetR family transcriptional regulator [Alkaliphilus metalliredigens QYMF] gi|149952213|gb|ABR50741.1| transcriptional regulator, TetR family [Alkaliphilus metalliredigens QYMF] Length=209 Score = 92.4 bits (228), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 52/165 (32%), Positives = 85/165 (52%), Gaps = 3/165 (1%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + +R ++ A EF + F S++ +A RA +AKGSL+QYF DK+DLY Sbjct 1 MPKQTFFNLPDEKRERIIGVAIEEFSKNSFDNASISKVAERANIAKGSLYQYFEDKKDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 F+ DIA+Q+ Y++D + E+D R FFE + L + + E+P+ + E Sbjct 61 KFMIDIATQKKMHYLKDCLEEMDELR-FFELIKKLYVRGILFAKENPQLVGIANHFLKEN 119 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDT--GALM 163 D + + + L L+ + RG++ + DT GA M Sbjct 120 DVKFKEEILGMGLEKSNQFLEQLIEERKQRGEINPEIDTKFGAHM 164 >gi|220933160|ref|YP_002510068.1| TetR family transcriptional regulator [Halothermothrix orenii H 168] gi|219994470|gb|ACL71073.1| transcriptional regulator, TetR family [Halothermothrix orenii H 168] Length=225 Score = 81.6 bits (200), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 49/179 (28%), Positives = 92/179 (52%), Gaps = 3/179 (1%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 +PT T+ + ++ V+EAA EF A+ + + S+ I +RA +A GS +QYF DK+DLY Sbjct 20 LPTSTFFNLPEEKKKRVIEAALDEFAAYPYHKASVTRIIKRAKIASGSFYQYFKDKKDLY 79 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 +I ++ ++R Y+ ++ E FFE L L + Y E+PR A+ Sbjct 80 KYILELGTERKFEYLGPVL-EKQNEYDFFELLRQLYVRGIKYARENPRLEAIANKLISNK 138 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYM 179 D++ + + R L+ D +G++ ++ D + +L+ + +LAL+ ++ Sbjct 139 DSEIYVEIIGEQRPRTARFFRALLEDGIKKGEIDSEVDIDLVAHMLITL--NLALSDFV 195 >gi|310657336|ref|YP_003935057.1| regulatory protein, tetr [Clostridium sticklandii DSM 519] gi|308824114|emb|CBH20152.1| putative Regulatory protein, TetR [Clostridium sticklandii] Length=209 Score = 80.1 bits (196), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 51/179 (29%), Positives = 84/179 (47%), Gaps = 11/179 (6%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + +R + A EF + + S++ I RA +AKGS +QYF DK DLY Sbjct 1 MPKETFFNLPEEKRQNIYNIAIDEFSNKPYEKVSISQIVSRAKIAKGSFYQYFEDKEDLY 60 Query 61 AFIADIASQRVRSYME---DLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAAT 117 ++ DI Q +ME D I ++D FFEF+ L V + A P + Sbjct 61 TYLIDIIGQEKIKFMEKDFDKIEDMD----FFEFVRLLYRNGVKFAAAEPNLTKIATGFM 116 Query 118 LEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALA 176 + + D + + S +D+ ++ A + +LR D D ++L I H+++A Sbjct 117 VNIPKDLKNKIISRNTTSAVDLFNAFIQKAMDKNELRDDID----VNLTSQILTHMSIA 171 >gi|116750511|ref|YP_847198.1| TetR family transcriptional regulator [Syntrophobacter fumaroxidans MPOB] gi|116699575|gb|ABK18763.1| transcriptional regulator, TetR family [Syntrophobacter fumaroxidans MPOB] Length=218 Score = 79.7 bits (195), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 51/167 (31%), Positives = 81/167 (49%), Gaps = 3/167 (1%) Query 2 PTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYA 61 P T+ ++ ++ ++++A EF GF + S+N I R G+AKGS+FQYF K L+ Sbjct 3 PRDTFKNLESRKKDRILDSAIEEFADQGFRQASINRIVRELGIAKGSIFQYFGSKEGLFH 62 Query 62 FIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVD 121 F+ D A VR + + +E FFE + + + + HPR ++ + D Sbjct 63 FVFDHAVDLVRRSLRQVKQETTET-DFFERIRRSILAGIQFIRRHPRVYRIYLKMIFQED 121 Query 122 TDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLL 168 R +H + LRPLV ARG+LR D + MS+ L Sbjct 122 FPLRAEFLQQVHLFSGEYLRPLVEAGIARGELRPDLNVE--MSVFFL 166 >gi|296132337|ref|YP_003639584.1| transcriptional regulator, TetR family [Thermincola sp. JR] gi|296030915|gb|ADG81683.1| transcriptional regulator, TetR family [Thermincola potens JR] Length=219 Score = 79.7 bits (195), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 44/158 (28%), Positives = 83/158 (53%), Gaps = 3/158 (1%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + +R +++ A EF +S+ SL+ I RAG+AKGS++QYF DK+DL+ Sbjct 1 MPRQTFFNLPEDKRKKIIDIALDEFAGRPYSKASLSRIVARAGIAKGSMYQYFEDKKDLF 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 ++ ++A++ +Y+E +E+DP+ FF + + + +HP+ + A A Sbjct 61 MYLLELAAREKLAYIE---QEVDPSADFFTAFAQSMLAGIRFNLDHPKLSRVIANAMDST 117 Query 121 DTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSD 158 +A + + L+ ++R +G +R D D Sbjct 118 GEEALHDFIAKGRKMTLEYFSQMIRRGQEQGSIRKDID 155 >gi|220931220|ref|YP_002508128.1| TetR family transcriptional regulator [Halothermothrix orenii H 168] gi|219992530|gb|ACL69133.1| transcriptional regulator, TetR family [Halothermothrix orenii H 168] Length=215 Score = 77.4 bits (189), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 45/173 (27%), Positives = 89/173 (52%), Gaps = 11/173 (6%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + ++ +++AA AEF ++G+ +GS+ IA RAG++KGS++QYF +K++L+ Sbjct 1 MPLKTYYNLPEEKQKRIIKAAIAEFASNGYQKGSIQSIADRAGISKGSMYQYFTNKKELF 60 Query 61 AFIADIASQRVRSYMEDLI---RELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHA--- 114 +I DIA + + ++++I R+L +E L + + Y E+P ++ Sbjct 61 LYIFDIAIDKKINGVKNIISRYRKL----TIYELLEKAFEDSIKYAREYPSLYQIYTRAI 116 Query 115 -AATLEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLL 166 A E+ +++ YL +L + R D+ + T + +L Sbjct 117 KGAPREIINSLDFKIKTEGLSFYLKLLTEARENGQVRDDINLELATFVVFTLC 169 >gi|332702866|ref|ZP_08422954.1| regulatory protein TetR [Desulfovibrio africanus str. Walvis Bay] gi|332553015|gb|EGJ50059.1| regulatory protein TetR [Desulfovibrio africanus str. Walvis Bay] Length=247 Score = 73.6 bits (179), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 60/206 (30%), Positives = 92/206 (45%), Gaps = 1/206 (0%) Query 2 PTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYA 61 P+ T+ ++PA+R V+EAA EF GF S+N + R G+AKGS+F+YF K+ L+ Sbjct 33 PSKTFGNLEPAKRERVIEAAVEEFSERGFEAASVNRMVARLGIAKGSIFKYFGSKQALFR 92 Query 62 FIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVD 121 F A+ + + +R+ + F + + L V + HPR L+ + D Sbjct 93 FAFGHAAAEFAASLRQ-VRDGSGDLDFCQRIRASLLAGVRFIDAHPRLYRLYLRVVFQED 151 Query 122 TDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRG 181 R + + LR LV D RG+LR D + L A + Sbjct 152 FPMRSPLLAEARAQSGKYLRRLVADGLERGELRPGLDPDWAVFFLDAAMDRFLQAYAVEH 211 Query 182 LDPILGLDEPTPEQPALAVRRLVAVL 207 +D GL PE A + +LV VL Sbjct 212 MDAACGLHRADPETLARRLDQLVDVL 237 >gi|220931221|ref|YP_002508129.1| TetR family transcriptional regulator [Halothermothrix orenii H 168] gi|219992531|gb|ACL69134.1| transcriptional regulator, TetR family [Halothermothrix orenii H 168] Length=221 Score = 71.6 bits (174), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 42/159 (27%), Positives = 83/159 (53%), Gaps = 3/159 (1%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + +R ++ A EF + ++ SL+ + +AG+AKGS++QYF +K++LY Sbjct 1 MPRETFFNLSEEKRNRIINIAVEEFARYDYNSASLSRVVEKAGIAKGSMYQYFKNKKELY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 ++ ++AS++ +Y+ D I + FF+ L ++ + + H L A E Sbjct 61 LYLVELASEKKFNYISDNIDFDTGKKDFFQLLKEMHLVGLKFDLTHLHYSNLILNAMRE- 119 Query 121 DTDARI-SVRSVLHRHYLDVLRPLVRDAHARGDLRADSD 158 T +I ++ L R + ++ ++ A +G +R D D Sbjct 120 -TSKKIGNLADRLIRSSDNYMKDFIKKAREKGQIRDDVD 157 >gi|320449430|ref|YP_004201526.1| transcriptional regulator [Thermus scotoductus SA-01] gi|320149599|gb|ADW20977.1| transcriptional regulator [Thermus scotoductus SA-01] Length=186 Score = 70.9 bits (172), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 53/176 (31%), Positives = 85/176 (49%), Gaps = 9/176 (5%) Query 13 RRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQRVR 72 ++ A++EA G S + +ARRA V KG+++ YF DK+DL + ++ +R Sbjct 12 KKRAILEATLEILREMGLSGLKMEEVARRAEVGKGTIYLYFRDKKDL---LKNLVEERTW 68 Query 73 SYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARISVRSVL 132 ++ ++ + PFF L LL +A+ AE R L AA E D ++ L Sbjct 69 AFYREVEEVVRQKAPFFVRLEGLLKKRLAWIAEW---RGLWAAVAREAMEDPTPWLKG-L 124 Query 133 HRHYLDVLRPLVRDAHARGDLRADSDTGALMSLL--LLIFPHLALAPYMRGLDPIL 186 H+HYLD+L LVR G +R + A ++ L P L + Y+ L +L Sbjct 125 HQHYLDLLEELVRSGQEEGAVRPELSPRATAHVIAALGCTPQLEVEAYLEHLMEVL 180 >gi|149923117|ref|ZP_01911532.1| hypothetical protein PPSIR1_13560 [Plesiocystis pacifica SIR-1] gi|149816025|gb|EDM75539.1| hypothetical protein PPSIR1_13560 [Plesiocystis pacifica SIR-1] Length=227 Score = 70.1 bits (170), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 63/183 (35%), Positives = 91/183 (50%), Gaps = 11/183 (6%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + +R + E A EF H + + SL+ I RAG+AKGS++QYF +K DLY Sbjct 1 MPKPTFLNLPDEKRQRITELAIDEFSTHPYRQASLSRIVARAGIAKGSMYQYFENKLDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEV 120 ++ +R R D + F E L V + +HPR L AAA +E Sbjct 61 QWLVVEELERRRRDWLDNHSHVRGEGLFAELEQRALAS-VGFLLDHPRLARL-AAAAMEP 118 Query 121 DTDARI-SVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYM 179 +DA + S+ S L ++ LD L + +A RG++R D D AL HL A + Sbjct 119 TSDAELRSLHSRLRQNELDALTRAIAEAMERGEIREDLDPRAL--------AHLIEAMVL 170 Query 180 RGL 182 RGL Sbjct 171 RGL 173 >gi|335038847|ref|ZP_08532049.1| transcriptional regulator, TetR family [Caldalkalibacillus thermarum TA2.A1] gi|334181263|gb|EGL83826.1| transcriptional regulator, TetR family [Caldalkalibacillus thermarum TA2.A1] Length=208 Score = 69.7 bits (169), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 29/85 (35%), Positives = 53/85 (63%), Gaps = 0/85 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 M T T+++++P+++ ++ AA AEF HG+ + S N I ++AG+ KG LF YF K++LY Sbjct 1 MITKTFSQLEPSKQQRIINAALAEFAEHGYEQASTNRIVKKAGIGKGMLFYYFNSKKELY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPN 85 ++ D + + LI + +P+ Sbjct 61 HYLVDYCLNYMTNNYLSLIDDSEPD 85 >gi|335427843|ref|ZP_08554763.1| TetR family transcriptional regulator [Haloplasma contractile SSD-17B] gi|334893769|gb|EGM31978.1| TetR family transcriptional regulator [Haloplasma contractile SSD-17B] Length=211 Score = 69.7 bits (169), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 40/161 (25%), Positives = 82/161 (51%), Gaps = 7/161 (4%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT T+ + +R ++++A EF + + + ++ IA++A ++KGS++QYF DK+DLY Sbjct 1 MPTETFFNLKQDKRDRILKSAINEFSRYSYQKTNIANIAKQANISKGSMYQYFKDKQDLY 60 Query 61 AFIADIASQRVRSYMEDLIRE-LDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLE 119 ++ +Q+ ++ + + LD PF + L +L V + +H L T E Sbjct 61 IYLIHYGTQKKMEFLGNTLNNRLD--HPFMDILRELYKQGVTFAIQHLELAKLFINFTKE 118 Query 120 VDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTG 160 D + ++ L ++ ++ D +G L+ + + G Sbjct 119 QD----LPFKNKLIEEGMEKSNRILADLLKKGKLKGEVNEG 155 >gi|118444554|ref|YP_877628.1| AcrR family transcriptional regulator [Clostridium novyi NT] gi|118135010|gb|ABK62054.1| Transcriptional regulator, AcrR family, putative [Clostridium novyi NT] Length=219 Score = 69.3 bits (168), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 54/103 (53%), Gaps = 4/103 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + R+ ++ + EF +H F S+N I G+AKGS ++YF +K DLY Sbjct 1 MPKQTFLNLSSERQKEIINISLKEFSSHNFETASMNKIITELGIAKGSFYRYFKNKNDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDP-NRPFFEFLTDLLDGWVAY 102 F+ D A + Y+E R +D + FFE ++ ++ + Sbjct 61 LFLLDYAVDKKIDYLE---RHIDTESNNFFEIYRSVVFNYMKF 100 >gi|212639401|ref|YP_002315921.1| TetR/AcrR family transcriptional regulator [Anoxybacillus flavithermus WK1] gi|212560881|gb|ACJ33936.1| Transcriptional regulator, TetR/AcrR family [Anoxybacillus flavithermus WK1] Length=216 Score = 68.6 bits (166), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 47/192 (25%), Positives = 83/192 (44%), Gaps = 13/192 (6%) Query 5 TWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIA 64 + R ++ ++ EF HG+ R S +VI RAG++KG LF YF K++LY ++ Sbjct 4 VFERQPEEKKKLIIHVTIEEFAQHGYDRASTDVIVNRAGISKGLLFHYFKSKKNLYLYVV 63 Query 65 DIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDA 124 A + + + + E+ N FFE + ++ F ++P E L A Sbjct 64 HYAKELLAEKTMEAVNEIRCN-DFFERIKQIVLIKQQIFMKYPHETQLVIDAVANPPKTV 122 Query 125 RISVRSVLHRHY------LDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPY 178 + + +L +HY + ++D + LR D + + +LI L+ Y Sbjct 123 KKEMEQLLAKHYETYAEDFQLQHIFLKDLLQKEALRDDVCVETVARMTMLIVEQLS-NKY 181 Query 179 M-----RGLDPI 185 M + DPI Sbjct 182 MQLYKHKQYDPI 193 >gi|168185353|ref|ZP_02619988.1| putative transcriptional regulator, AcrR family [Clostridium botulinum C str. Eklund] gi|169296492|gb|EDS78625.1| putative transcriptional regulator, AcrR family [Clostridium botulinum C str. Eklund] Length=219 Score = 67.8 bits (164), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 27/76 (36%), Positives = 43/76 (57%), Gaps = 0/76 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + R+ ++ + EF +H F S+N I G+AKGS ++YF +K+DLY Sbjct 1 MPKQTFLNLSRERQKEIINVSLKEFSSHNFETSSMNKIITELGIAKGSFYRYFKNKKDLY 60 Query 61 AFIADIASQRVRSYME 76 F+ D A + Y+E Sbjct 61 LFLLDYAVDKKIDYLE 76 >gi|335351151|gb|EGM52645.1| TetR/AcrR family transcriptional regulator [Lactobacillus salivarius GJ-24] Length=216 Score = 67.8 bits (164), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 31/83 (38%), Positives = 49/83 (60%), Gaps = 3/83 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ +D ++ V++AA F +H ++ S+N + + A + +GS +QYF DKRDLY Sbjct 1 MPKETFFGIDNEKQNRVIQAAIKVFSSHNYNDSSINEVIKLAKIPRGSFYQYFEDKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELD 83 +IA Q R+ D +ELD Sbjct 61 LYIAQKIIQNFRN---DFFKELD 80 >gi|163848264|ref|YP_001636308.1| regulatory protein TetR [Chloroflexus aurantiacus J-10-fl] gi|222526174|ref|YP_002570645.1| TetR family transcriptional regulator [Chloroflexus sp. Y-400-fl] gi|163669553|gb|ABY35919.1| regulatory protein TetR [Chloroflexus aurantiacus J-10-fl] gi|222450053|gb|ACM54319.1| transcriptional regulator, TetR family [Chloroflexus sp. Y-400-fl] Length=216 Score = 67.4 bits (163), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 49/176 (28%), Positives = 80/176 (46%), Gaps = 7/176 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT T+ + +R+ +++ EF + + S+N I RAG+AKGS +QYFADK+D Y Sbjct 1 MPTETFFNLPEEKRSRLIDVLLDEFAQNDYDSVSINRITERAGIAKGSFYQYFADKKDCY 60 Query 61 AFIADIASQRVRSYMEDLIRELDP--NRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL 118 ++ + ++ +++ R+ P F +L LLD + + +PR A A L Sbjct 61 LYLIQLGIEQKTAFL----RQTPPASTTDMFAYLRWLLDVGIQFQFHNPR-LAQIAYKAL 115 Query 119 EVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLA 174 D V+ + LV A G L D D +L ++F L Sbjct 116 YDDVPLPAETMQVIRHGSFAYFKQLVEQGIADGSLVPDLDADTAAFVLNVVFTELG 171 >gi|334307407|gb|EGL98393.1| transcriptional regulator, TetR family [Lactobacillus salivarius NIAS840] Length=216 Score = 67.4 bits (163), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 28/83 (34%), Positives = 52/83 (63%), Gaps = 3/83 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ +D ++ +++AA F +H ++ S+N + + A + +GS +QYF DKRDLY Sbjct 1 MPKETFFGIDKEKQNRIIQAAIKVFSSHNYNDSSINEVIKLAKIPRGSFYQYFEDKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELD 83 + IA + ++++ +D +ELD Sbjct 61 LY---IAQKIIQNFRDDFFKELD 80 >gi|312142674|ref|YP_003994120.1| TetR family transcriptional regulator [Halanaerobium hydrogeniformans] gi|311903325|gb|ADQ13766.1| transcriptional regulator, TetR family [Halanaerobium hydrogeniformans] Length=214 Score = 67.4 bits (163), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 30/107 (29%), Positives = 60/107 (57%), Gaps = 1/107 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + +R +++A EF A+ + + S N I A ++KGS +QYF +K+DLY Sbjct 1 MPKQTFFNLPSKKRERILQAGMEEFSAYPYLKSSTNRIIENADISKGSFYQYFDNKKDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHP 107 +I A+ ++ + + + + + FF++L +L G + + ++P Sbjct 61 KYIIKKATDEKIEFLNEQLVDFEK-QSFFDYLRELFIGGIKFKKQYP 106 >gi|219670673|ref|YP_002461108.1| TetR family transcriptional regulator [Desulfitobacterium hafniense DCB-2] gi|219540933|gb|ACL22672.1| transcriptional regulator, TetR family [Desulfitobacterium hafniense DCB-2] Length=217 Score = 67.4 bits (163), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 37/110 (34%), Positives = 61/110 (56%), Gaps = 5/110 (4%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT T+ + A+R ++EAA EF A+ F + S+ I +AG+ +GS +QYF + +DLY Sbjct 1 MPTQTFFNLPEAKRTRIIEAATREFAAYAFDQASIARIIEQAGIPRGSFYQYFENLKDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVA---YFAEHP 107 +I D++ ++ Y + + L FEF + L +V + EHP Sbjct 61 KYIFDLSVEKKLQYFDAKVPALHGEG--FEFFSTLQRVFVVGLEFAREHP 108 >gi|156740970|ref|YP_001431099.1| TetR family transcriptional regulator [Roseiflexus castenholzii DSM 13941] gi|156232298|gb|ABU57081.1| transcriptional regulator, TetR family [Roseiflexus castenholzii DSM 13941] Length=216 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 51/170 (30%), Positives = 81/170 (48%), Gaps = 15/170 (8%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MPT T+ + +RA +++ EF + + S+ I RAG+AKGS +QYFADK+D Y Sbjct 1 MPTETFFNLPEEKRARLLDVLLDEFSQNDYDNVSIGRITERAGIAKGSFYQYFADKKDCY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPR-----ERALHAA 115 ++ +A + +++ E P+ F L L++ + + +PR +AL Sbjct 61 LYLIQLAIEEKTTFLRRQPSE--PSTDLFAHLRRLIEAGMQFQFRNPRLAHIAYKALFDD 118 Query 116 ATLEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDL--RADSDTGALM 163 A L +T +V+ R R LV A G L R DSD A + Sbjct 119 APLPEET------LNVIRRGGYAYFRSLVESGIANGSLDPRIDSDIAAFV 162 >gi|218294628|ref|ZP_03495482.1| transcriptional regulator, TetR family [Thermus aquaticus Y51MC23] gi|218244536|gb|EED11060.1| transcriptional regulator, TetR family [Thermus aquaticus Y51MC23] Length=186 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 54/178 (31%), Positives = 86/178 (49%), Gaps = 11/178 (6%) Query 12 ARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQRV 71 +R A+++A G S + +AR+A V KG+++ YF DK+DL + + + Sbjct 11 GKREAILQATLEVLREKGLSGLKMEDVARKAEVGKGTIYLYFRDKKDLLKTLVEERTWAF 70 Query 72 RSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARISVRSV 131 +E+++R PFF L LL +A+ AE R L AA E D ++ Sbjct 71 YREVEEIVR---LRAPFFVRLERLLQKRLAWIAEW---RGLWAAVAREAMADPTPWLKG- 123 Query 132 LHRHYLDVLRPLVRDAHARGDLRAD---SDTGALMSLLLLIFPHLALAPYMRGLDPIL 186 LH+HYLD+L LV+ G +R + T A+M+ L P L + Y+ L +L Sbjct 124 LHQHYLDLLEELVKSGQEEGAVRPELSPKATAAVMA-ALGCNPQLEVEAYLEHLLLVL 180 >gi|225181254|ref|ZP_03734699.1| transcriptional regulator, TetR family [Dethiobacter alkaliphilus AHT 1] gi|225168034|gb|EEG76840.1| transcriptional regulator, TetR family [Dethiobacter alkaliphilus AHT 1] Length=219 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 51/199 (26%), Positives = 91/199 (46%), Gaps = 7/199 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 M + + + V+EAA EF F SLN I +AG++KGS++ YF +K DLY Sbjct 1 MVKQGFLNLSQQEQKQVLEAALDEFSKRDFKTASLNSIIEQAGISKGSMYHYFHNKEDLY 60 Query 61 AFIADI----ASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAA 116 ++ +I S+ + + ++DL R + FE LT L+ V + E+PR ++ Sbjct 61 LYLMEIIMVEKSRFLAAALQDLKRPVQE-LSMFETLTLQLNTAVQFARENPRYHLINKQL 119 Query 117 TLEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALA 176 D + + + + ++ +A G+LR+D D + +L F L Sbjct 120 QDMPDGALKQKIWGRFTVEFDKYMNSMITNAIKNGELRSDLDRKFITRVLR--FVMLNFT 177 Query 177 PYMRGLDPILGLDEPTPEQ 195 + + +L +DE +Q Sbjct 178 DFYPDYNELLQMDEEELQQ 196 >gi|317132259|ref|YP_004091573.1| regulatory protein TetR [Ethanoligenens harbinense YUAN-3] gi|315470238|gb|ADU26842.1| regulatory protein TetR [Ethanoligenens harbinense YUAN-3] Length=209 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 40/137 (30%), Positives = 69/137 (51%), Gaps = 12/137 (8%) Query 9 VDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIAS 68 ++ ++A ++ AA EF G+ S N I R+AG++KG LF YF +K+ LY F+ D A+ Sbjct 8 LNAEKQARILNAALEEFAKKGYKNASTNEIVRKAGISKGLLFHYFGNKKRLYLFLYDYAN 67 Query 69 QRVRSYMEDLIRELDPNRP-FFEFLTDLLDGWVAYFAEHPRERALHAAATL--------E 119 + + LD R F+ L +++ + +HP ATL E Sbjct 68 D---VFTNEFFNRLDYGRADLFKRLKQMIELKIELSRKHPDLYEFMVCATLEDVGGIKSE 124 Query 120 VDTDARISVRSVLHRHY 136 ++T +RIS++ + R + Sbjct 125 IETKSRISIQDSMARAF 141 >gi|222100510|ref|YP_002535078.1| Transcriptional regulator, TetR family [Thermotoga neapolitana DSM 4359] gi|221572900|gb|ACM23712.1| Transcriptional regulator, TetR family [Thermotoga neapolitana DSM 4359] Length=200 Score = 66.6 bits (161), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 33/98 (34%), Positives = 57/98 (59%), Gaps = 1/98 (1%) Query 12 ARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQRV 71 +++ A+++AA FG G+ R + + IA RAGVAKG +F +F K +LY +++ Sbjct 2 SKKEAILKAAIEVFGKRGYERATTDEIAERAGVAKGLIFHHFKSKENLYHQAYRYVVEKL 61 Query 72 RSYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRE 109 + E+ +RE + NR F+F+ ++ + Y A HP E Sbjct 62 QGEFENFLRE-NKNRDIFDFMEKWMEKKLEYSANHPEE 98 >gi|336428058|ref|ZP_08608046.1| hypothetical protein HMPREF0994_04052 [Lachnospiraceae bacterium 3_1_57FAA_CT1] gi|336007553|gb|EGN37577.1| hypothetical protein HMPREF0994_04052 [Lachnospiraceae bacterium 3_1_57FAA_CT1] Length=258 Score = 66.6 bits (161), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 27/76 (36%), Positives = 45/76 (60%), Gaps = 0/76 (0%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP + + +R ++ A + EF +G++ S N + R AG++KGSLFQYF +K +LY Sbjct 46 MPAKIFEELSEEKRRRIIAACKTEFSEYGYTGSSTNRMIRNAGISKGSLFQYFRNKEELY 105 Query 61 AFIADIASQRVRSYME 76 ++ D Q + Y+E Sbjct 106 FYVLDCVIQELTEYLE 121 >gi|227891870|ref|ZP_04009675.1| TetR/AcrR family transcriptional regulator [Lactobacillus salivarius ATCC 11741] gi|227866333|gb|EEJ73754.1| TetR/AcrR family transcriptional regulator [Lactobacillus salivarius ATCC 11741] gi|300214118|gb|ADJ78534.1| Transcriptional regulator, TetR family [Lactobacillus salivarius CECT 5713] Length=216 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 29/83 (35%), Positives = 48/83 (58%), Gaps = 3/83 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ +D ++ +++AA F +H ++ S+N + + A + +GS +QYF DKRDLY Sbjct 1 MPKETFFGIDKEKQNRIIQAAIKVFSSHNYNDSSINEVIKLAKIPRGSFYQYFEDKRDLY 60 Query 61 AFIADIASQRVRSYMEDLIRELD 83 +I Q R +D +ELD Sbjct 61 LYITQKIMQNFR---DDFFKELD 80 >gi|253681556|ref|ZP_04862353.1| transcriptional regulator, TetR family [Clostridium botulinum D str. 1873] gi|253561268|gb|EES90720.1| transcriptional regulator, TetR family [Clostridium botulinum D str. 1873] Length=220 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 53/103 (52%), Gaps = 4/103 (3%) Query 1 MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLY 60 MP T+ + R+ +++ + EF H F S+N I G+AKGS ++YF K+ LY Sbjct 1 MPKQTFLNLPRERQKEIIDISLKEFSCHSFETASMNKIITELGIAKGSFYRYFKSKKALY 60 Query 61 AFIADIASQRVRSYMEDLIRELDPN-RPFFEFLTDLLDGWVAY 102 F+ D A + Y+E R +D N FFE ++ ++ + Sbjct 61 LFLLDYAVNKKIDYLE---RHIDINGNNFFEIYRSVIFNYMKF 100 Lambda K H 0.324 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 297403917052 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40