BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0238 Length=204 Score E Sequences producing significant alignments: (Bits) Value gi|15607379|ref|NP_214752.1| TetR family transcriptional regulat... 421 4e-116 gi|340625276|ref|YP_004743728.1| putative transcriptional regula... 419 1e-115 gi|339293302|gb|AEJ45413.1| TetR family transcriptional regulato... 388 2e-106 gi|183980528|ref|YP_001848819.1| TetR family transcriptional reg... 352 1e-95 gi|118616881|ref|YP_905213.1| TetR family transcriptional regula... 350 6e-95 gi|342859286|ref|ZP_08715940.1| TetR family transcriptional regu... 349 1e-94 gi|240168463|ref|ZP_04747122.1| TetR family transcriptional regu... 349 1e-94 gi|254820432|ref|ZP_05225433.1| transcriptional regulator, TetR ... 349 2e-94 gi|41409787|ref|NP_962623.1| hypothetical protein MAP3689 [Mycob... 348 3e-94 gi|108797216|ref|YP_637413.1| TetR family transcriptional regula... 337 8e-91 gi|120401283|ref|YP_951112.1| TetR family transcriptional regula... 331 4e-89 gi|118467472|ref|YP_884776.1| TetR family transcriptional regula... 328 3e-88 gi|15828381|ref|NP_302644.1| TetR family transcriptional regulat... 327 7e-88 gi|145221018|ref|YP_001131696.1| TetR family transcriptional reg... 320 8e-86 gi|289568142|ref|ZP_06448369.1| transcriptional regulator, tetR-... 312 1e-83 gi|296167521|ref|ZP_06849873.1| TetR family transcriptional regu... 308 3e-82 gi|289748720|ref|ZP_06508098.1| transcriptional regulator, tetR-... 308 4e-82 gi|333988861|ref|YP_004521475.1| TetR family transcriptional reg... 307 6e-82 gi|289756304|ref|ZP_06515682.1| transcriptional regulatory prote... 279 2e-73 gi|169631523|ref|YP_001705172.1| TetR family transcriptional reg... 254 6e-66 gi|313665981|gb|ADR72658.1| TetR [Rhodococcus sp. BCP1] 232 3e-59 gi|312141420|ref|YP_004008756.1| tetr family transcriptional reg... 226 2e-57 gi|325673159|ref|ZP_08152852.1| TetR family transcriptional regu... 226 2e-57 gi|226304607|ref|YP_002764565.1| TetR family transcriptional reg... 221 6e-56 gi|111022164|ref|YP_705136.1| transcriptional regulator [Rhodoco... 219 1e-55 gi|262204274|ref|YP_003275482.1| TetR family transcriptional reg... 218 5e-55 gi|296138161|ref|YP_003645404.1| TetR family transcriptional reg... 214 4e-54 gi|343924461|ref|ZP_08764010.1| putative TetR family transcripti... 211 4e-53 gi|213424544|pdb|3F1B|A Chain A, The Crystal Structure Of A Tetr... 210 1e-52 gi|326385232|ref|ZP_08206897.1| regulatory protein TetR [Gordoni... 207 5e-52 gi|54027438|ref|YP_121680.1| putative transcriptional regulator ... 206 1e-51 gi|333921767|ref|YP_004495348.1| TetR family transcriptional reg... 206 2e-51 gi|319950257|ref|ZP_08024178.1| TetR family transcriptional regu... 172 4e-41 gi|145592704|ref|YP_001157001.1| TetR family transcriptional reg... 156 2e-36 gi|300791031|ref|YP_003771322.1| TetR family transcriptional reg... 154 1e-35 gi|159035817|ref|YP_001535070.1| TetR family transcriptional reg... 152 3e-35 gi|238062059|ref|ZP_04606768.1| TetR family transcriptional regu... 147 6e-34 gi|256380958|ref|YP_003104618.1| TetR family transcriptional reg... 146 2e-33 gi|302864705|ref|YP_003833342.1| regulatory protein TetR [Microm... 145 2e-33 gi|257057827|ref|YP_003135659.1| transcriptional regulator, TetR... 144 8e-33 gi|291452055|ref|ZP_06591445.1| TetR-family transcriptional regu... 139 4e-31 gi|345008454|ref|YP_004810808.1| regulatory protein TetR [Strept... 135 4e-30 gi|302553350|ref|ZP_07305692.1| TetR family transcriptional regu... 134 6e-30 gi|134103723|ref|YP_001109384.1| TetR/AcrR family transcriptiona... 134 6e-30 gi|297192809|ref|ZP_06910207.1| TetR-family transcriptional regu... 134 7e-30 gi|297159492|gb|ADI09204.1| TetR family transcriptional regulato... 134 7e-30 gi|29831359|ref|NP_825993.1| TetR family transcriptional regulat... 134 1e-29 gi|291300502|ref|YP_003511780.1| TetR family transcriptional reg... 134 1e-29 gi|297201579|ref|ZP_06918976.1| TetR-family transcriptional regu... 131 8e-29 gi|291445549|ref|ZP_06584939.1| TetR-family transcriptional regu... 129 2e-28 >gi|15607379|ref|NP_214752.1| TetR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15839619|ref|NP_334656.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31791416|ref|NP_853909.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97] 70 more sequence titles Length=204 Score = 421 bits (1081), Expect = 4e-116, Method: Compositional matrix adjust. Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA Sbjct 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDRLETGH 204 AEMMINLFWLGLKGAPVDRLETGH Sbjct 181 AEMMINLFWLGLKGAPVDRLETGH 204 >gi|340625276|ref|YP_004743728.1| putative transcriptional regulatory protein [Mycobacterium canettii CIPT 140010059] gi|340003466|emb|CCC42586.1| putative transcriptional regulatory protein (probably TETR-family) [Mycobacterium canettii CIPT 140010059] Length=204 Score = 419 bits (1076), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 203/204 (99%), Positives = 203/204 (99%), Gaps = 0/204 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLG GDTDVDEA Sbjct 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGTGDTDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDRLETGH 204 AEMMINLFWLGLKGAPVDRLETGH Sbjct 181 AEMMINLFWLGLKGAPVDRLETGH 204 >gi|339293302|gb|AEJ45413.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CCDC5079] gi|339296948|gb|AEJ49058.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CCDC5180] Length=188 Score = 388 bits (997), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 188/188 (100%), Positives = 188/188 (100%), Gaps = 0/188 (0%) Query 17 MLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALR 76 MLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALR Sbjct 1 MLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALR 60 Query 77 SSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVA 136 SSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVA Sbjct 61 SSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVA 120 Query 137 ELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAP 196 ELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAP Sbjct 121 ELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAP 180 Query 197 VDRLETGH 204 VDRLETGH Sbjct 181 VDRLETGH 188 >gi|183980528|ref|YP_001848819.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183173854|gb|ACC38964.1| transcriptional regulatory protein (probably TetR-family) [Mycobacterium marinum M] Length=208 Score = 352 bits (904), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 169/199 (85%), Positives = 180/199 (91%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRA+REQQMLDAAVQMFS NGYHETSMD IAA AQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFIDA+R+ I+ QSPKDLLRN IVSFLRYID N+ASWIVMYTQA SSQAF Sbjct 61 GACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLRYIDQNQASWIVMYTQAVSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A TVREGREQIV+LVA ++RAGTR P +DAEI+MMA ALVGAGEAVA RL GDTDVDEA Sbjct 121 AQTVREGREQIVELVAGMLRAGTRSPRSDAEIDMMAAALVGAGEAVANRLSAGDTDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 AEMMI+LFW GLKGAP DR Sbjct 181 AEMMIDLFWRGLKGAPSDR 199 >gi|118616881|ref|YP_905213.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118568991|gb|ABL03742.1| transcriptional regulatory protein (probably TetR-family) [Mycobacterium ulcerans Agy99] Length=208 Score = 350 bits (898), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 168/199 (85%), Positives = 179/199 (90%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRA+REQQMLDAAVQMFS NGYHETSMD IAA AQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFIDA+R+ I+ QSPKDLLRN IVSFLRYID N+ASWIVMYTQA SSQAF Sbjct 61 GACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLRYIDQNQASWIVMYTQAVSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A TVREGREQIV+LVA ++RAGTR P +DAEI+MMA ALVGAGEAVA RL GDTDVDEA Sbjct 121 AQTVREGREQIVELVAGMLRAGTRSPRSDAEIDMMAAALVGAGEAVANRLSAGDTDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 AEMMI+L W GLKGAP DR Sbjct 181 AEMMIDLLWRGLKGAPSDR 199 >gi|342859286|ref|ZP_08715940.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342133527|gb|EGT86730.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=216 Score = 349 bits (896), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 165/199 (83%), Positives = 181/199 (91%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREM RFID +R+ ++F QSPKD+LRNTI SF+RYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNREMGRFIDVVRADVDFQQSPKDMLRNTIASFMRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AH VREGREQI+ LVA L+RAG+R P ++ E EMMAVALVGAGEAVA RL GD DVDEA Sbjct 121 AHMVREGREQIIDLVAGLMRAGSRNPRSEREHEMMAVALVGAGEAVANRLSTGDVDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 A++MI+LFW GLKG+P +R Sbjct 181 AQLMIDLFWYGLKGSPAER 199 >gi|240168463|ref|ZP_04747122.1| TetR family transcriptional regulator [Mycobacterium kansasii ATCC 12478] Length=212 Score = 349 bits (896), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 168/199 (85%), Positives = 180/199 (91%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFS+NGYHETSMD IAA AQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSLNGYHETSMDTIAAAAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREM+RFIDALR+ I+ SPKDLLRN IVSFLRYID NRASWIVMYTQATSSQAF Sbjct 61 GACLNREMNRFIDALRADIDLTVSPKDLLRNAIVSFLRYIDTNRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A TVREGREQI+ LVA ++ AGTR P +DAEI+MMAVALVGAGEAV TRL +GD DVDEA Sbjct 121 AQTVREGREQIIDLVAGMLHAGTRSPRSDAEIDMMAVALVGAGEAVGTRLSVGDIDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 AEMMI+LFW GLKGAP +R Sbjct 181 AEMMIDLFWHGLKGAPAER 199 >gi|254820432|ref|ZP_05225433.1| transcriptional regulator, TetR family protein [Mycobacterium intracellulare ATCC 13950] Length=214 Score = 349 bits (895), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 167/199 (84%), Positives = 180/199 (91%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREM+RFID LR+ I+F QSP D+LRNTI SF+RYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNREMTRFIDVLRADIDFRQSPNDMLRNTIASFMRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AH VREGREQI+ LVA L+RAG+R P D E EMMAVALVGAGEAVA RL GD DVDEA Sbjct 121 AHMVREGREQIIDLVAGLMRAGSRAPRPDIEHEMMAVALVGAGEAVANRLSTGDIDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 A++MI+LFW GLKG+P +R Sbjct 181 AQLMIDLFWYGLKGSPEER 199 >gi|41409787|ref|NP_962623.1| hypothetical protein MAP3689 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118463516|ref|YP_884040.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777358|ref|ZP_05218874.1| transcriptional regulator, TetR family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|41398619|gb|AAS06239.1| hypothetical protein MAP_3689 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118164803|gb|ABK65700.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] gi|336460128|gb|EGO39034.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=215 Score = 348 bits (892), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 166/199 (84%), Positives = 181/199 (91%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAA+AQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAQAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNRE+ RFIDA+R+ I+F QSP D+LRNTI SF+RYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNRELGRFIDAVRADIDFQQSPNDMLRNTIASFMRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AH VREGREQI++LVA L+RAG+R P TD E EMMAVALVGAGEAVA RL GD DVDEA Sbjct 121 AHMVREGREQIIELVAGLMRAGSRTPRTDREHEMMAVALVGAGEAVANRLSTGDIDVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 A +MI+LFW GLKG+P +R Sbjct 181 AALMIDLFWYGLKGSPEER 199 >gi|108797216|ref|YP_637413.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119866301|ref|YP_936253.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|126432839|ref|YP_001068530.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|108767635|gb|ABG06357.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119692390|gb|ABL89463.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] gi|126232639|gb|ABN96039.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=218 Score = 337 bits (863), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 157/198 (80%), Positives = 176/198 (89%), Gaps = 0/198 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACL+RE+ RF+D +RS I+F Q +DLLRN ++SFL YID NRASW+V+YTQATSSQAF Sbjct 61 GACLDRELGRFVDEVRSKIDFSQGARDLLRNAVLSFLTYIDTNRASWMVLYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AHTVREGRE+I++LV+ L+R GTR P D + EMMAVALVGAGEA+ATR+ GD DVDEA Sbjct 121 AHTVREGRERIIELVSRLLREGTRHPEPDTDFEMMAVALVGAGEAIATRVSTGDADVDEA 180 Query 181 AEMMINLFWLGLKGAPVD 198 AE+MINLFW GLKG P D Sbjct 181 AELMINLFWRGLKGTPSD 198 >gi|120401283|ref|YP_951112.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954101|gb|ABM11106.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=209 Score = 331 bits (849), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 151/196 (78%), Positives = 179/196 (92%), Gaps = 0/196 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAV++FSVNGYHETSMDAIAAEAQISKPMLYLYYGSKE+LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNRE+ RF+D + S+I+F +PK+LLR +++FL+YIDANRASW+V+YTQATSSQAF Sbjct 61 GACLNRELGRFVDEVNSNIDFSAAPKELLRTAVLAFLKYIDANRASWMVLYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AHTVREGRE+I++LV L+R+GT+ P D + E+MAVALVGAGEA+A+R+ GD DVDEA Sbjct 121 AHTVREGRERIIELVGRLLRSGTKFPEPDTDFELMAVALVGAGEAIASRVSTGDADVDEA 180 Query 181 AEMMINLFWLGLKGAP 196 AE+MINLFWLGLKGAP Sbjct 181 AELMINLFWLGLKGAP 196 >gi|118467472|ref|YP_884776.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118168759|gb|ABK69655.1| TetR-family protein regulatory protein [Mycobacterium smegmatis str. MC2 155] Length=212 Score = 328 bits (841), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 153/198 (78%), Positives = 174/198 (88%), Gaps = 0/198 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAA A+ISKPMLYLYYGSKE+LF Sbjct 3 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAAAEISKPMLYLYYGSKEELF 62 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACL+RE+ RF+D +R I+F QSPK+LLR +++FL YID NRASW+V+YTQATSSQAF Sbjct 63 GACLDRELRRFVDTVRGQIDFSQSPKELLRTAVLAFLTYIDRNRASWMVLYTQATSSQAF 122 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AHTVREGRE+I+ LVA L+ GTR P D++ EMMAVALVGAGEA+ATR+ GD DVDEA Sbjct 123 AHTVREGRERIIDLVARLLSTGTRNPQPDSDFEMMAVALVGAGEAIATRVSTGDADVDEA 182 Query 181 AEMMINLFWLGLKGAPVD 198 AE+MINLFW GLKG P D Sbjct 183 AELMINLFWRGLKGTPSD 200 >gi|15828381|ref|NP_302644.1| TetR family transcriptional regulator [Mycobacterium leprae TN] gi|221230858|ref|YP_002504274.1| putative TetR-family transcriptional regulator [Mycobacterium leprae Br4923] gi|3063879|emb|CAA18564.1| putative transcriptional regulator [Mycobacterium leprae] gi|13093811|emb|CAC32099.1| possible TetR-family transcriptional regulator [Mycobacterium leprae] gi|219933965|emb|CAR72667.1| possible TetR-family transcriptional regulator [Mycobacterium leprae Br4923] Length=208 Score = 327 bits (837), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 161/199 (81%), Positives = 172/199 (87%), Gaps = 0/199 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGG KR+PRAVREQQMLDAAVQMFSVNGYH+TSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFI +R+ I+F QSPKDLLRNTIVSFLRYIDANRASWIVMY QA S AF Sbjct 61 GACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A TVRE R+QI +LVA L+R GTR D E E+MA ALVGAGEA+ATRL GD VDEA Sbjct 121 AQTVREARDQITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEA 180 Query 181 AEMMINLFWLGLKGAPVDR 199 AE+MINLFW GLKGAP DR Sbjct 181 AELMINLFWHGLKGAPADR 199 >gi|145221018|ref|YP_001131696.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|315442010|ref|YP_004074889.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|145213504|gb|ABP42908.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] gi|315260313|gb|ADT97054.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=215 Score = 320 bits (820), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 146/196 (75%), Positives = 176/196 (90%), Gaps = 0/196 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAV++FSVNGYHETSMDAIAAEAQISKPMLYLYYGSKE+LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACL+RE++RF+D + S+I+F PK+LLR +++FL YIDANRASW+V+YTQATSSQAF Sbjct 61 GACLHRELTRFVDEVNSNIDFTAPPKELLRTAVLAFLNYIDANRASWMVLYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 AHTVREGRE+I+++V L+R+GTR P D + +MMAVALVGAGEA+A+R+ GD DV EA Sbjct 121 AHTVREGRERIIEIVGRLLRSGTRFPEPDTDFDMMAVALVGAGEAIASRVSTGDADVHEA 180 Query 181 AEMMINLFWLGLKGAP 196 +E+MINLFW GLKG+P Sbjct 181 SELMINLFWRGLKGSP 196 >gi|289568142|ref|ZP_06448369.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis T17] gi|289541895|gb|EFD45544.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis T17] Length=150 Score = 312 bits (800), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 150/150 (100%), Positives = 150/150 (100%), Gaps = 0/150 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDA 150 AHTVREGREQIVQLVAELVRAGTRGPLTDA Sbjct 121 AHTVREGREQIVQLVAELVRAGTRGPLTDA 150 >gi|296167521|ref|ZP_06849873.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897143|gb|EFG76752.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=200 Score = 308 bits (789), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 147/178 (83%), Positives = 162/178 (92%), Gaps = 0/178 (0%) Query 17 MLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALR 76 MLDAAVQMFSVNGYHETSMDAIAA+AQISKPMLYLYYGSKEDLFGACL+REM RFIDA+R Sbjct 1 MLDAAVQMFSVNGYHETSMDAIAAQAQISKPMLYLYYGSKEDLFGACLHREMGRFIDAVR 60 Query 77 SSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVA 136 + I+F QSPKDLLRNTIV+F+RYIDANRASWIVMYTQATSSQAFAH VREGREQI++LVA Sbjct 61 ADIDFTQSPKDLLRNTIVAFMRYIDANRASWIVMYTQATSSQAFAHVVREGREQIIELVA 120 Query 137 ELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKG 194 LVRAG+R P + E EMMAVALVGAGEA+A +L GD D DEAAE+MINLFW GL+G Sbjct 121 GLVRAGSRSPRAEREDEMMAVALVGAGEAMANQLSTGDIDADEAAELMINLFWHGLRG 178 >gi|289748720|ref|ZP_06508098.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis T92] gi|289689307|gb|EFD56736.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis T92] Length=165 Score = 308 bits (788), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 152/158 (97%), Positives = 153/158 (97%), Gaps = 4/158 (2%) Query 47 PMLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRAS 106 P+L L KEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRAS Sbjct 12 PVLRL----KEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRAS 67 Query 107 WIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAV 166 WIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAV Sbjct 68 WIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAV 127 Query 167 ATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDRLETGH 204 ATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDRLETGH Sbjct 128 ATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDRLETGH 165 >gi|333988861|ref|YP_004521475.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333484829|gb|AEF34221.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] Length=197 Score = 307 bits (786), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 144/188 (77%), Positives = 167/188 (89%), Gaps = 0/188 (0%) Query 12 VREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRF 71 +REQQMLDAAVQMFS+NGYHETSMD+IAA AQISKPMLYLYYGSKE+LFGACL+RE++RF Sbjct 1 MREQQMLDAAVQMFSINGYHETSMDSIAAAAQISKPMLYLYYGSKEELFGACLDRELARF 60 Query 72 IDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVREGREQI 131 ++ +R+SI+F QSPKDLLRNTI SFL YID NRASWIVMY+QATSSQAFAHTVREGRE+I Sbjct 61 VETVRTSIDFQQSPKDLLRNTIRSFLHYIDTNRASWIVMYSQATSSQAFAHTVREGRERI 120 Query 132 VQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLG 191 V+LV L+RAGTR P + +MMAVALVGAGEA+A+R+ GDTDVDEA E+MI+LFW G Sbjct 121 VELVGRLLRAGTRNPEPGVDFDMMAVALVGAGEAIASRVSTGDTDVDEAGELMIDLFWRG 180 Query 192 LKGAPVDR 199 LK AP R Sbjct 181 LKEAPGGR 188 >gi|289756304|ref|ZP_06515682.1| transcriptional regulatory protein (probably tetR-family) [Mycobacterium tuberculosis EAS054] gi|289696891|gb|EFD64320.1| transcriptional regulatory protein (probably tetR-family) [Mycobacterium tuberculosis EAS054] Length=140 Score = 279 bits (713), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 133/133 (100%), Positives = 133/133 (100%), Gaps = 0/133 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF Sbjct 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 Query 121 AHTVREGREQIVQ 133 AHTVREGREQIVQ Sbjct 121 AHTVREGREQIVQ 133 >gi|169631523|ref|YP_001705172.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169243490|emb|CAM64518.1| Putative transcriptional regulator, TetR family [Mycobacterium abscessus] Length=205 Score = 254 bits (648), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 127/200 (64%), Positives = 159/200 (80%), Gaps = 4/200 (2%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAVQ F++NG+ +TSMDAIAA A+ISKPMLYLYYGSKEDLF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVQEFALNGFRDTSMDAIAAAAKISKPMLYLYYGSKEDLF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 ACL RE+ RF++A+R I+ QSP+D+L T+VSFL Y+D +RASWIV+Y QATS+Q F Sbjct 61 VACLRRELGRFVEAVRGDIDLTQSPRDVLSTTVVSFLNYVDTHRASWIVIYGQATSTQLF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEM--MAVALVGAGEAVATRLGIGDTDVD 178 A VREGR++I++LVA L++A + P D E + MAVALVG GEAVA+R+ GD V+ Sbjct 121 AKQVREGRDRIIELVARLIKAAS--PEIDPETDYDAMAVALVGGGEAVASRVATGDIKVE 178 Query 179 EAAEMMINLFWLGLKGAPVD 198 A + ++NL W GL+G P D Sbjct 179 SAKDTLLNLGWRGLRGRPRD 198 >gi|313665981|gb|ADR72658.1| TetR [Rhodococcus sp. BCP1] Length=199 Score = 232 bits (591), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 112/191 (59%), Positives = 147/191 (77%), Gaps = 0/191 (0%) Query 4 GTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGAC 63 GTKRLPRAVREQQMLDAAV++FS NG+H TSMDAIAA AQISKPMLYLYYGSK++LF AC Sbjct 1 GTKRLPRAVREQQMLDAAVEVFSENGFHNTSMDAIAARAQISKPMLYLYYGSKDELFAAC 60 Query 64 LNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHT 123 ++RE RF++AL + + +P+D LR + SFL ++DA+R SW+V+Y QA S QAFA Sbjct 61 ISREGQRFVEALTPAGDPGLTPRDQLRVALESFLGFVDAHRNSWMVLYRQAMSQQAFAGQ 120 Query 124 VREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEM 183 VR R+++++L A L+ + TR P + +MAVALVGAGEAVA R+ G+ DV++AA++ Sbjct 121 VRSSRDRLIELTAHLLESSTRDPEPGTDFAIMAVALVGAGEAVADRIAGGEIDVEKAADL 180 Query 184 MINLFWLGLKG 194 + NL W GL G Sbjct 181 LENLAWRGLAG 191 >gi|312141420|ref|YP_004008756.1| tetr family transcriptional regulator [Rhodococcus equi 103S] gi|311890759|emb|CBH50078.1| putative TetR family transcriptional regulator [Rhodococcus equi 103S] Length=200 Score = 226 bits (576), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 106/194 (55%), Positives = 144/194 (75%), Gaps = 0/194 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAA+++FS NG+H+ SMDAIAA A ISKPMLYLYYGSK++LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAIEVFSDNGFHDASMDAIAARANISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC++RE RF++A+ + + + P++ LR + FL ++DANR SW+V+Y QA Q F Sbjct 61 AACIHREGVRFVEAISPAGDPNLPPREQLRAALAGFLGFVDANRRSWMVLYRQAIGQQTF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A V R+++++L A+L+ + T+ P + +MAVALVGAGEAVA R+ G+ DVD A Sbjct 121 ASQVSSSRDRLIELTAKLLESSTKDPEPGTDFSIMAVALVGAGEAVADRVAGGEIDVDAA 180 Query 181 AEMMINLFWLGLKG 194 +++ NL W GL G Sbjct 181 VDLLENLAWRGLAG 194 >gi|325673159|ref|ZP_08152852.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] gi|325555994|gb|EGD25663.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] Length=201 Score = 226 bits (575), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 106/194 (55%), Positives = 144/194 (75%), Gaps = 0/194 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAA+++FS NG+H+ SMDAIAA A ISKPMLYLYYGSK++LF Sbjct 2 MAGGTKRLPRAVREQQMLDAAIEVFSDNGFHDASMDAIAARANISKPMLYLYYGSKDELF 61 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC++RE RF++A+ + + + P++ LR + FL ++DANR SW+V+Y QA Q F Sbjct 62 AACIHREGVRFVEAISPAGDPNLPPREQLRAALAGFLGFVDANRRSWMVLYRQAIGQQTF 121 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A V R+++++L A+L+ + T+ P + +MAVALVGAGEAVA R+ G+ DVD A Sbjct 122 ASQVSSSRDRLIELTAKLLESSTKDPEPGTDFSIMAVALVGAGEAVADRVAGGEIDVDAA 181 Query 181 AEMMINLFWLGLKG 194 +++ NL W GL G Sbjct 182 VDLLENLAWRGLAG 195 >gi|226304607|ref|YP_002764565.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|229494568|ref|ZP_04388331.1| TetR-family regulatory protein [Rhodococcus erythropolis SK121] gi|226183722|dbj|BAH31826.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|229318930|gb|EEN84788.1| TetR-family regulatory protein [Rhodococcus erythropolis SK121] Length=199 Score = 221 bits (562), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 107/194 (56%), Positives = 146/194 (76%), Gaps = 0/194 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAV +FS G+HETSMD IAA+A+ISKPMLYLYYGSKE+LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVDVFSDRGFHETSMDTIAAKAEISKPMLYLYYGSKEELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC++RE RF++AL + + +P++ LR + FL ++ ANR SW+V+Y QA QAF Sbjct 61 AACIHREGLRFLEALAPAGAPNLTPREQLRAALEGFLGFVGANRKSWMVLYRQAVGQQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A TV+ R+++++L A L+ + T+ P + ++A+ALVGAGEAVA R+ G+ +VD A Sbjct 121 AGTVQSSRDRLIELTAHLLESSTKDPDAAHDYGIIAIALVGAGEAVADRVAGGEIEVDAA 180 Query 181 AEMMINLFWLGLKG 194 A+++ +L W GL G Sbjct 181 ADLLESLAWRGLSG 194 >gi|111022164|ref|YP_705136.1| transcriptional regulator [Rhodococcus jostii RHA1] gi|226364657|ref|YP_002782439.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|110821694|gb|ABG96978.1| probable transcriptional regulator [Rhodococcus jostii RHA1] gi|226243146|dbj|BAH53494.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=199 Score = 219 bits (559), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 105/194 (55%), Positives = 145/194 (75%), Gaps = 0/194 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAV +FS G+HETSMDAIAA+A+ISKPMLYLYYGSK++LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVDVFSDRGFHETSMDAIAAKAEISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC+ RE RF++AL + + SP++ LR + FL ++ +R SW+V+Y QA QAF Sbjct 61 AACIQREGLRFVEALAPAGDPGLSPREQLRRALEGFLGFVGKHRKSWMVLYRQAMGQQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 +V+ R+++++L A L+ + T+ P + E++A+ALVGAGEAVA R+ G+ +VD A Sbjct 121 VGSVQSSRDRLIELTAHLLESSTKDPEPGQDFELIAIALVGAGEAVADRVAGGEIEVDAA 180 Query 181 AEMMINLFWLGLKG 194 A+++ +L W GL G Sbjct 181 ADLLESLAWRGLAG 194 >gi|262204274|ref|YP_003275482.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262087621|gb|ACY23589.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=202 Score = 218 bits (554), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 108/200 (54%), Positives = 143/200 (72%), Gaps = 1/200 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 M+GGTKRLPRAVREQQMLDAAV++F+ NG+ E SMDAIAAEAQISKPMLYLYYGSK++LF Sbjct 1 MSGGTKRLPRAVREQQMLDAAVKVFAQNGFREASMDAIAAEAQISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 GACL RE FI+A+ + + S +D R I FLR++ + SW V+Y A + F Sbjct 61 GACLARESGLFIEAMSVGFDPNLSQRDQARTVIREFLRFVHQHSQSWRVLYRVAIGTANF 120 Query 121 AHTVREGREQIVQLVAELVRAGTR-GPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDE 179 A V + R+++ ++VAEL++AGT +D + E+ AVALVGA EAVA R+ GD D+D Sbjct 121 AQLVSDSRQRVTEMVAELIKAGTTVEGASDIDFELTAVALVGASEAVADRITEGDVDLDT 180 Query 180 AAEMMINLFWLGLKGAPVDR 199 A ++++ + W GLKG DR Sbjct 181 ATDLLVGIAWRGLKGVGTDR 200 >gi|296138161|ref|YP_003645404.1| TetR family transcriptional regulator [Tsukamurella paurometabola DSM 20162] gi|296026295|gb|ADG77065.1| transcriptional regulator, TetR family [Tsukamurella paurometabola DSM 20162] Length=201 Score = 214 bits (546), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 107/208 (52%), Positives = 144/208 (70%), Gaps = 11/208 (5%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAA+++FS NG++ETSMDA+A EA+ISKPMLYLYYGSK++LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAIKVFSRNGFYETSMDAVAREAEISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQS----PKDLLRNTIVSFLRYIDANRASWIVMYTQATS 116 AC+ RE+ F+ SI FD + P LR+ I FL+Y+D NR +W VMY +A+ Sbjct 61 AACVTREVGHFM----RSIEFDATPALPPSQRLRSVIEGFLKYVDQNRDAWRVMYREASG 116 Query 117 SQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTD 176 +FA V RE++V++ A L+R + D + E+ AVALVG+GEA+A RL G + Sbjct 117 QASFATLVEANRERVVEMTAVLLREAAKYAPEDTDFELYAVALVGSGEAIADRLATGKVE 176 Query 177 VDEAAEMMINLFWLGLKGAPVDRLETGH 204 +D A E+M + W G++G +R E G Sbjct 177 LDRAVEIMTSFLWGGIRG---ERPEDGK 201 >gi|343924461|ref|ZP_08764010.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343765605|dbj|GAA10936.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=204 Score = 211 bits (538), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 108/201 (54%), Positives = 143/201 (72%), Gaps = 5/201 (2%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 M+GGTKRLPRAVREQQMLDAAV++F+ NG+ ETSMDAIA+EAQISKPMLYLYYGSKE+LF Sbjct 5 MSGGTKRLPRAVREQQMLDAAVKVFAQNGFRETSMDAIASEAQISKPMLYLYYGSKEELF 64 Query 61 GACLNREMSRFIDALRSSINFDQS--PKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQ 118 AC+ RE FIDA+ S+ FD S ++ I FLR++ NR SW V+Y A + Sbjct 65 SACIARESGLFIDAM--SVGFDPSLTQREQAVTVIREFLRFVHENRESWRVLYRVAIGTA 122 Query 119 AFAHTVREGREQIVQLVAELVRAGTRGPLT-DAEIEMMAVALVGAGEAVATRLGIGDTDV 177 +FA V + R+++ ++VA L++AGT D + E+ AVA+VGA EAVA R+ GD D+ Sbjct 123 SFAGIVSDSRQRVTEMVAALIKAGTTVETAGDIDFELTAVAIVGACEAVADRITEGDVDL 182 Query 178 DEAAEMMINLFWLGLKGAPVD 198 ++A M++ + W GLKG D Sbjct 183 EKATNMLVGIAWRGLKGVGTD 203 >gi|213424544|pdb|3F1B|A Chain A, The Crystal Structure Of A Tetr-Like Transcriptional Regulator From Rhodococcus Sp. Rha1. Length=203 Score = 210 bits (534), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 101/193 (53%), Positives = 140/193 (73%), Gaps = 0/193 (0%) Query 2 AGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFG 61 AGGTKRLPRAVREQQ LDAAV +FS G+HETS DAIAA+A+ISKP LYLYYGSK++LF Sbjct 4 AGGTKRLPRAVREQQXLDAAVDVFSDRGFHETSXDAIAAKAEISKPXLYLYYGSKDELFA 63 Query 62 ACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFA 121 AC+ RE RF++AL + + SP++ LR + FL ++ +R SW V+Y QA QAF Sbjct 64 ACIQREGLRFVEALAPAGDPGLSPREQLRRALEGFLGFVGKHRKSWXVLYRQAXGQQAFV 123 Query 122 HTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAA 181 +V+ R+++++L A L+ + T+ P + E++A+ALVGAGEAVA R+ G+ +VD AA Sbjct 124 GSVQSSRDRLIELTAHLLESSTKDPEPGQDFELIAIALVGAGEAVADRVAGGEIEVDAAA 183 Query 182 EMMINLFWLGLKG 194 +++ +L W GL G Sbjct 184 DLLESLAWRGLAG 196 >gi|326385232|ref|ZP_08206897.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] gi|326196051|gb|EGD53260.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] Length=207 Score = 207 bits (528), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 102/198 (52%), Positives = 137/198 (70%), Gaps = 1/198 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MA GTKRLPRAVREQQMLDAA+ F+ NG+ +TSMDAIAAEA+ISKPMLYLYYGSK++LF Sbjct 1 MASGTKRLPRAVREQQMLDAAISAFAANGFADTSMDAIAAEAKISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC+ RE RF++A+ + + KD R + FLR++ N+ SW V+Y A + +F Sbjct 61 SACIARESGRFLEAMSAGFDPAMRQKDQARTLVREFLRFVYQNQDSWRVLYRVAVGTTSF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGP-LTDAEIEMMAVALVGAGEAVATRLGIGDTDVDE 179 AH V E R I ++ +L+R GT D + E+ AVALVGAGEAVA R+ GD D++ Sbjct 121 AHIVTESRAGITTMITDLIRRGTTTEGAGDVDFELTAVALVGAGEAVADRISEGDIDLET 180 Query 180 AAEMMINLFWLGLKGAPV 197 A ++++ + W GL+G V Sbjct 181 ATDLLLGITWRGLRGVGV 198 >gi|54027438|ref|YP_121680.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] gi|54018946|dbj|BAD60316.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] Length=199 Score = 206 bits (525), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 100/194 (52%), Positives = 139/194 (72%), Gaps = 0/194 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 MAGGTKRLPRAVREQQMLDAAV++F+ G+H+TSMDAIAAEA+ISKPMLYLYYGSK++LF Sbjct 1 MAGGTKRLPRAVREQQMLDAAVEVFARKGFHDTSMDAIAAEAKISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC+ RE R I+A+ + N SP + LR + +FL ++D NR SW V+Y QA QAF Sbjct 61 RACIQREGIRLIEAVAPAGNPLLSPHEQLRTALEAFLGFVDRNRRSWQVLYRQAIGQQAF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A + RE++++L A+L+ + + +++A A++GAGEA+A R+ G +V EA Sbjct 121 ASEIDNARERVIELTAKLLESSAKHAEPGTNFDIVAAAVIGAGEAIADRVAGGRIEVSEA 180 Query 181 AEMMINLFWLGLKG 194 +++ +L W GL G Sbjct 181 VDLLDDLAWSGLAG 194 >gi|333921767|ref|YP_004495348.1| TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333483988|gb|AEF42548.1| TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] Length=198 Score = 206 bits (523), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 97/194 (50%), Positives = 138/194 (72%), Gaps = 0/194 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 M G KRLPRA+REQQMLDAA+ +F+ +GYH SM+AIAA A+ISKPMLYLYYGSK++LF Sbjct 1 MTGRPKRLPRAIREQQMLDAAIDVFAEHGYHAASMNAIAARAEISKPMLYLYYGSKDELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 +C+ RE +RF+DAL + + SP++ L + I +FL ++ NR SW VMY QA ++F Sbjct 61 ASCIRRESTRFLDALTGAADPSLSPREQLTHGIRAFLGFVHENRQSWHVMYRQAMYQKSF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 A V RE+ ++L A ++R+ +R P ++ + +MA AL+GAGEAVA R+ G D + A Sbjct 121 ADLVTGSRERAIELTALILRSSSREPHSNEQFRLMASALIGAGEAVADRIADGSIDKEAA 180 Query 181 AEMMINLFWLGLKG 194 ++++NL W GL G Sbjct 181 VDLLVNLGWRGLAG 194 >gi|319950257|ref|ZP_08024178.1| TetR family transcriptional regulator [Dietzia cinnamea P4] gi|319436055|gb|EFV91254.1| TetR family transcriptional regulator [Dietzia cinnamea P4] Length=208 Score = 172 bits (435), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 90/202 (45%), Positives = 123/202 (61%), Gaps = 0/202 (0%) Query 1 MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLF 60 M GTKR+PRA+RE+QMLD+A+++FS GY SMD IA A ISKPMLYLYYGSKE+LF Sbjct 1 MTTGTKRIPRAIREKQMLDSAIRVFSDLGYRSASMDTIARHASISKPMLYLYYGSKEELF 60 Query 61 GACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAF 120 AC+ RE R ID L ++ P+ L + + +FL ++DA+ SW V+Y QA + F Sbjct 61 AACVVRESGRLIDHLTAAATGSAGPRRRLEDVVQAFLEFVDAHTDSWNVVYRQAFAEPQF 120 Query 121 AHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 V + R +V L +L+ + + +E++A ALVGAGEAVA R+ A Sbjct 121 REEVEKTRTVLVDLTTDLLAQNSGDERSREVLEVVATALVGAGEAVADRVAHRSIPTSVA 180 Query 181 AEMMINLFWLGLKGAPVDRLET 202 A +++ L W GL G P L T Sbjct 181 AGVVVELAWRGLAGDPTKSLTT 202 >gi|145592704|ref|YP_001157001.1| TetR family transcriptional regulator [Salinispora tropica CNB-440] gi|145302041|gb|ABP52623.1| transcriptional regulator, TetR family [Salinispora tropica CNB-440] Length=218 Score = 156 bits (394), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 88/190 (47%), Positives = 123/190 (65%), Gaps = 4/190 (2%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 +RLPRAVREQQMLDAAV++FS GYH SMD IA +A ISKPM+Y Y G+KE+LF ACL+ Sbjct 8 RRLPRAVREQQMLDAAVKVFSRRGYHGASMDEIADDAGISKPMVYAYLGTKEELFVACLH 67 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVR 125 RE +R A+ S++ D S + L ++ +FL ++ A+R W V+Y QA Q FA + Sbjct 68 REGNRMTQAVTSAVAPDLSADERLWRSLRAFLGFVGAHRDGWAVLYRQARGEQPFAGEIA 127 Query 126 EGREQIVQLVAELVRAGTRGPLTDA---EIEMMAVALVGAGEAVATRL-GIGDTDVDEAA 181 R +IV++V EL+ R +A E+E+ A ALVGA E+VA L + D ++ A Sbjct 128 AMRRRIVEVVTELLDHTLRAEGREAAEVELEVAAYALVGATESVADWLVDHPEADPEQTA 187 Query 182 EMMINLFWLG 191 M+N+ W+G Sbjct 188 TRMMNVAWVG 197 >gi|300791031|ref|YP_003771322.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299800545|gb|ADJ50920.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340532729|gb|AEK47934.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=218 Score = 154 bits (388), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 88/195 (46%), Positives = 124/195 (64%), Gaps = 8/195 (4%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 +RLPRAVRE+Q+LDAAVQ+FS +GYH SMD I+ A +SKPM+Y Y GSKEDLFGAC+ Sbjct 13 RRLPRAVRERQILDAAVQVFSRHGYHAASMDEISDVAGVSKPMIYTYLGSKEDLFGACIR 72 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHTV 124 RE +R ++A+++ + D P L + + SF R++ R SW V++ QA T AFA + Sbjct 73 REATRLLEAIQAGVQPDLPPDMQLWHGLRSFYRFVAEYRESWTVLHRQALTVGGAFAAEI 132 Query 125 REGREQIVQLVAEL-VRAGTR---GPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEA 180 + R + +QLVA L V AGTR G + E ++ ALVGA E++A + D+ + Sbjct 133 TDMRARAIQLVAALVVSAGTRKGVGEQAEFSGEGLSAALVGAAESLAD-WALDHPDISDG 191 Query 181 --AEMMINLFWLGLK 193 A ++NL WLG Sbjct 192 VLASWLMNLVWLGFN 206 >gi|159035817|ref|YP_001535070.1| TetR family transcriptional regulator [Salinispora arenicola CNS-205] gi|157914652|gb|ABV96079.1| transcriptional regulator, TetR family [Salinispora arenicola CNS-205] Length=224 Score = 152 bits (384), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 85/191 (45%), Positives = 126/191 (66%), Gaps = 6/191 (3%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 +RLPRAVREQQMLDAAV++FS GYH SMD IA +A ISKPM+Y Y G+KE+LF ACL+ Sbjct 8 RRLPRAVREQQMLDAAVKVFSRRGYHAASMDEIADDAGISKPMVYAYLGTKEELFIACLH 67 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVR 125 RE +R + A+ ++ D S + L ++ +FL ++ A+R W V+Y QA Q FA + Sbjct 68 REGTRMMQAIAGAVAPDLSADERLWRSLRAFLGFVGAHRDGWAVLYRQARGEQPFAGEIA 127 Query 126 EGREQIVQLVAEL----VRAGTRGPLTDAEIEMMAVALVGAGEAVATRL-GIGDTDVDEA 180 R ++V++VA + +RA R + + E+E++A ALVGA E+VA L + D ++ Sbjct 128 AMRSRMVEIVAGMLAHTLRAECR-EVAETELEVVAYALVGATESVADWLVDHPEADPEQT 186 Query 181 AEMMINLFWLG 191 A ++N+ W+G Sbjct 187 ATRVMNVAWVG 197 >gi|238062059|ref|ZP_04606768.1| TetR family transcriptional regulator [Micromonospora sp. ATCC 39149] gi|237883870|gb|EEP72698.1| TetR family transcriptional regulator [Micromonospora sp. ATCC 39149] Length=211 Score = 147 bits (372), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 82/190 (44%), Positives = 121/190 (64%), Gaps = 4/190 (2%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 KRLPRAVREQQMLDAAV++FS G+H SMD IA +A ISKPM+Y Y G+KE+LF ACL+ Sbjct 8 KRLPRAVREQQMLDAAVRVFSRRGFHAASMDEIAEDAGISKPMVYAYLGTKEELFVACLH 67 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVR 125 RE +R +A+ + D + L + +F ++ A+R W V+Y QA SQ FA + Sbjct 68 REGTRMTEAIAGAAAPDLDADERLWRGLRAFFGFVGAHRDGWAVLYRQARGSQPFAGELA 127 Query 126 EGREQIVQLVAELVRAGTRG---PLTDAEIEMMAVALVGAGEAVATRLG-IGDTDVDEAA 181 R ++V++VA ++ R ++ ++E++A ALVGA E++A L + D ++ A Sbjct 128 AMRARLVEVVAGMLDHALRARGREVSATDLEVVAYALVGASESLADWLADHPEADPEKTA 187 Query 182 EMMINLFWLG 191 M+N+ WLG Sbjct 188 TRMMNVAWLG 197 >gi|256380958|ref|YP_003104618.1| TetR family transcriptional regulator [Actinosynnema mirum DSM 43827] gi|255925261|gb|ACU40772.1| transcriptional regulator, TetR family [Actinosynnema mirum DSM 43827] Length=220 Score = 146 bits (368), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 89/198 (45%), Positives = 121/198 (62%), Gaps = 8/198 (4%) Query 2 AGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFG 61 AG KRLPRAVRE+Q+LDAAV +FS G+H SMD I+ A ISKPMLY Y GSKE+LF Sbjct 9 AGRAKRLPRAVRERQILDAAVDVFSRLGFHAASMDEISEVAGISKPMLYAYLGSKEELFT 68 Query 62 ACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQA-F 120 AC RE +R ++A+ + + D++ L + +F ++ +RASW+V++ QATS F Sbjct 69 ACTRRESARLMEAIATGVEVDRAADVQLWTGLRAFFGFVGEHRASWLVLHRQATSQGGPF 128 Query 121 AHTVREGREQIVQLVAEL-----VRAGTRGPLTDAEIEMMAVALVGAGEAVAT-RLGIGD 174 A + E R + + LVAEL V AG G + + E MA ALVGAGE++A L D Sbjct 129 AAELAELRGRAIGLVAELVARAAVEAGVPG-TGERDAESMAAALVGAGESLADWWLDHPD 187 Query 175 TDVDEAAEMMINLFWLGL 192 A ++NL W+G Sbjct 188 EPSGVVAARLMNLVWMGF 205 >gi|302864705|ref|YP_003833342.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029] gi|315500999|ref|YP_004079886.1| regulatory protein TetR [Micromonospora sp. L5] gi|302567564|gb|ADL43766.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029] gi|315407618|gb|ADU05735.1| regulatory protein TetR [Micromonospora sp. L5] Length=217 Score = 145 bits (367), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 81/190 (43%), Positives = 119/190 (63%), Gaps = 4/190 (2%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 KRLPRAVREQQMLDAAV++FS G+H SMD IA +A ISKPM+Y Y G+KE+LF ACL+ Sbjct 12 KRLPRAVREQQMLDAAVKVFSRRGFHAASMDEIADDAGISKPMVYAYLGTKEELFIACLH 71 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHTVR 125 RE +R ++A+ + D + L + +F ++ A+R W V+Y QA SQ FA + Sbjct 72 RESTRMMEAIAGAAAPDLPADERLWRGLRAFFGFVGAHRDGWAVLYRQARGSQPFAAELA 131 Query 126 EGREQIVQLVAELVRAGTRGP---LTDAEIEMMAVALVGAGEAVATRLG-IGDTDVDEAA 181 R ++V++VA ++ R + ++E++A LVGA E++A L + D + A Sbjct 132 AMRGRLVEVVAGMLDHALRASGREVGATDLEVVAYGLVGASESLADWLADHPEADAGKTA 191 Query 182 EMMINLFWLG 191 M+N+ WLG Sbjct 192 TRMMNVAWLG 201 >gi|257057827|ref|YP_003135659.1| transcriptional regulator, TetR family [Saccharomonospora viridis DSM 43017] gi|256587699|gb|ACU98832.1| transcriptional regulator, TetR family [Saccharomonospora viridis DSM 43017] Length=226 Score = 144 bits (363), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 88/195 (46%), Positives = 121/195 (63%), Gaps = 8/195 (4%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 KRLPRAVRE+Q+LDAAV++FS +GYH SMD I+ A +SKPM+Y Y G+KE+LFG C+ Sbjct 21 KRLPRAVREKQILDAAVEVFSQHGYHMASMDVISEVAGVSKPMIYSYLGAKEELFGHCIR 80 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSS-QAFAHTV 124 RE +R +A+R I D P L + + SF ++ R SWIV++ A ++ FA V Sbjct 81 RESNRLFEAVRDGIRPDVPPDMQLWHGLRSFYGFVAEYRQSWIVLHRHALAAGDPFAKEV 140 Query 125 REGREQIVQLVAEL-VRAGT-RGPLTDAEI--EMMAVALVGAGEAVATRLGIGDTDVDEA 180 R + ++LV +L V AGT RG + AE E MA ALVGA E++A + + V E Sbjct 141 TALRTRAIELVRDLVVSAGTQRGLASQAEFSGEGMAAALVGAAESLAD-WWLDNPHVPEG 199 Query 181 --AEMMINLFWLGLK 193 A ++NL WLG Sbjct 200 VLASWLMNLTWLGFN 214 >gi|291452055|ref|ZP_06591445.1| TetR-family transcriptional regulator [Streptomyces albus J1074] gi|291355004|gb|EFE81906.1| TetR-family transcriptional regulator [Streptomyces albus J1074] Length=219 Score = 139 bits (349), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 83/200 (42%), Positives = 112/200 (56%), Gaps = 13/200 (6%) Query 3 GGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGA 62 G +KR+PR VRE+QMLDAAV F+ +GY SMD IA A +SKP++YLY SKEDLF A Sbjct 11 GRSKRMPREVRERQMLDAAVATFARHGYRAASMDGIAELAGVSKPLVYLYLNSKEDLFTA 70 Query 63 CLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFA 121 C+ RE + + A+R ++ P L + +F + + W V++ QA TS + FA Sbjct 71 CIRREAAALVRAVRQGVDPATPPDRQLWEGLGAFFTHTAEHPDGWAVLHNQARTSGEPFA 130 Query 122 HTVREGREQIVQLVAELVRAGTR-----GPLTDAEIEMMAVALVGAGEAVATRLGIGDTD 176 V R +V V EL+ A R L D E+ +A ALVGA E++A G DTD Sbjct 131 REVATMRADLVAFVTELIAAAAREAHDDPELGDREVAGLAHALVGAAESLA---GWADTD 187 Query 177 ----VDEAAEMMINLFWLGL 192 EAA ++N W GL Sbjct 188 GSVTAKEAASTLMNFAWAGL 207 >gi|345008454|ref|YP_004810808.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344034803|gb|AEM80528.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=222 Score = 135 bits (339), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 79/204 (39%), Positives = 113/204 (56%), Gaps = 13/204 (6%) Query 2 AGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFG 61 A G+KR+PRAVREQQMLDA V+ F+ +GY SMD IA A +SKP++YLY SKE+LF Sbjct 4 ATGSKRVPRAVREQQMLDAGVRAFARSGYQNASMDDIAELAGVSKPLVYLYLNSKEELFT 63 Query 62 ACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAF 120 AC+ RE + A+R+++ D L + + F + + W +++ QA T Q + Sbjct 64 ACIRREAVALVTAVRAAVERDAPADRQLWSGLSGFFAHAAEHPDGWTLLHVQARTHGQPY 123 Query 121 AHTVREGREQIVQLVAELVRAGTRG---------PLTDAEIEMMAVALVGAGEAVATRLG 171 A V R +IV+ V +L+ A R L E+ +A ALVGA E++A G Sbjct 124 AREVAAMRAEIVEFVTQLIGAAAREHARGAARARTLAGTEVSGLAHALVGAAESLADWAG 183 Query 172 ---IGDTDVDEAAEMMINLFWLGL 192 +G EAA ++N W GL Sbjct 184 DGRVGGHSAKEAAATLMNFAWAGL 207 >gi|302553350|ref|ZP_07305692.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302470968|gb|EFL34061.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=231 Score = 134 bits (338), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 83/208 (40%), Positives = 111/208 (54%), Gaps = 20/208 (9%) Query 5 TKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACL 64 TKR+PRAVREQQMLDAAVQ+F GY SMD IA A +SKP++YLY SKEDLF AC+ Sbjct 6 TKRMPRAVREQQMLDAAVQIFGQRGYRAASMDEIAELAGVSKPLVYLYLNSKEDLFTACI 65 Query 65 NREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHT 123 RE + ++A+R+ + D L + +F + N SW V++ QA T + FA Sbjct 66 RREAAALVEAVRAGVRRDLPADRQLWEGLGAFFTHTARNPDSWAVLHLQARTHGEPFAAE 125 Query 124 VREGREQIVQLVAELVRAGTRGPLTDA------------------EIEMMAVALVGAGEA 165 V RE+IV V +L+ A R L A E+ +A ALVGA E+ Sbjct 126 VTAMREEIVAFVTQLILAAAREALPQALGCARAGRHPHDPDLPEREVGGLAEALVGAAES 185 Query 166 VATRL-GIGDTDVDEAAEMMINLFWLGL 192 +A +AA ++N W GL Sbjct 186 LAAWANATPGVTARQAAATLMNFAWAGL 213 >gi|134103723|ref|YP_001109384.1| TetR/AcrR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291010039|ref|ZP_06568012.1| TetR/AcrR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133916346|emb|CAM06459.1| transcriptional regulator (TetR/AcrR family) [Saccharopolyspora erythraea NRRL 2338] Length=219 Score = 134 bits (338), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 76/193 (40%), Positives = 116/193 (61%), Gaps = 5/193 (2%) Query 5 TKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACL 64 TKRLPR+VRE+Q+LDAAV +F+ +G+H+ SMD I+ A ISKPM+Y Y GSKE+LF AC+ Sbjct 15 TKRLPRSVRERQILDAAVDVFAAHGFHQASMDEISEVAGISKPMIYAYLGSKEELFVACI 74 Query 65 NREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSS-QAFAHT 123 RE +R +DA+R +++ P L + SF Y R+SW V++ QA + + F+ Sbjct 75 QREAARLLDAIRGAVDTGLRPDQQLWRGLRSFFEYTQQYRSSWAVLHRQANAQGEPFSIE 134 Query 124 VREGREQIVQLVAELVRAGTRGP---LTDAEIEMMAVALVGAGEA-VATRLGIGDTDVDE 179 + + R + ++A L+ T + +++ A ALVGAGE+ V L D D Sbjct 135 LAQWRSRTRDVIAMLLARATESAEQQMQPEQMQPFAAALVGAGESLVDWWLDNPDHTADG 194 Query 180 AAEMMINLFWLGL 192 A ++N+ W+G Sbjct 195 MAMRLMNMVWMGF 207 >gi|297192809|ref|ZP_06910207.1| TetR-family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] gi|197722357|gb|EDY66265.1| TetR-family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] Length=225 Score = 134 bits (337), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 81/207 (40%), Positives = 112/207 (55%), Gaps = 17/207 (8%) Query 5 TKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACL 64 TKR+PRAVREQQM+DAAV+ F GY SMD IA A +SKP++YLY SKE+LF AC+ Sbjct 9 TKRMPRAVREQQMMDAAVRTFGQLGYRAASMDEIAELAGVSKPLVYLYLNSKEELFTACI 68 Query 65 NREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHT 123 RE R +A++++I + + + +F R+ N W V++ QA T + FA Sbjct 69 RREAQRLTEAVQAAIQPGLTADRQMWAGLEAFFRHTQENPDGWSVLHRQARTHGEPFAAE 128 Query 124 VREGREQIVQLVAELVRAGTR---------------GPLTDAEIEMMAVALVGAGEAVAT 168 V RE+I V L+ A R L D ++E +A ALVGA E++A Sbjct 129 VARMREEIAAFVTVLIGAAARQGVPPAPGATGSNRSAELADRDVEGLAQALVGAAESLAG 188 Query 169 RLG-IGDTDVDEAAEMMINLFWLGLKG 194 G EAA +++N W GL G Sbjct 189 WANEAGGISAKEAAGLLMNFAWTGLGG 215 >gi|297159492|gb|ADI09204.1| TetR family transcriptional regulator [Streptomyces bingchenggensis BCW-1] Length=215 Score = 134 bits (337), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 77/198 (39%), Positives = 109/198 (56%), Gaps = 13/198 (6%) Query 8 LPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNRE 67 +PRAVREQQMLDAAV+ F+ GY SMD IA +A +SKP++YLY SK++LF AC+ RE Sbjct 1 MPRAVREQQMLDAAVRTFARRGYRNASMDDIAEQAGVSKPLVYLYLNSKDELFAACIRRE 60 Query 68 MSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHTVRE 126 + + A+R+++ D L + + F Y + W +++ QA T FA V Sbjct 61 AASLVAAIRAAVEHDAPADRRLWSGLHGFFTYTAEHPDGWALLHVQARTHGDPFAREVAA 120 Query 127 GREQIVQLVAELVRAGTR---------GPLTDAEIEMMAVALVGAGEAVATRLG---IGD 174 R +IV+ V L+R R G +T E +A ALVGA E++A G G Sbjct 121 MRAEIVEFVTHLLRTAVREHGCGAARTGRMTGGEAAGLAYALVGAAESLAEWAGGRADGG 180 Query 175 TDVDEAAEMMINLFWLGL 192 +EAA ++N W GL Sbjct 181 PSAEEAAATLMNFAWAGL 198 >gi|29831359|ref|NP_825993.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29608474|dbj|BAC72528.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=213 Score = 134 bits (336), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/195 (42%), Positives = 107/195 (55%), Gaps = 7/195 (3%) Query 5 TKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACL 64 KR+PRAVREQQMLDAAV F GY SMD IA A +SKP++YLY SKEDLF AC+ Sbjct 6 NKRMPRAVREQQMLDAAVHTFGQRGYRAASMDEIAELAGVSKPLVYLYLNSKEDLFTACI 65 Query 65 NREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHT 123 RE A+R+ + L + + +F + N +W V++ QA T + FA Sbjct 66 RREAKALTAAVRAGVRPGLPADRQLWDGLTAFFTHTAQNPDAWSVLHLQARTHGEPFAAE 125 Query 124 VREGREQIVQLVAELV----RAGTRGP-LTDAEIEMMAVALVGAGEAVATRLGIGD-TDV 177 V RE+IV V +L+ RA R P L + E+ +A ALVGA E++A Sbjct 126 VTAMREEIVAFVTQLIVVAARAAHRNPSLPEREVAGLAEALVGAAESLAAWANTAPGVSA 185 Query 178 DEAAEMMINLFWLGL 192 +AA ++N W GL Sbjct 186 KQAAATLMNFAWAGL 200 >gi|291300502|ref|YP_003511780.1| TetR family transcriptional regulator [Stackebrandtia nassauensis DSM 44728] gi|290569722|gb|ADD42687.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis DSM 44728] Length=209 Score = 134 bits (336), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 76/192 (40%), Positives = 116/192 (61%), Gaps = 6/192 (3%) Query 6 KRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN 65 KR+PRA+REQQMLDA+V++F+ GYH ++ IA A ISKPM+YLY+GSKE+LF AC+ Sbjct 7 KRVPRAIREQQMLDASVEVFARRGYHPAGVEEIAEIAGISKPMVYLYFGSKEELFVACIR 66 Query 66 REMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHTV 124 RE +R ++ + ++ PK+ L + + F ++ + +WIV+Y QA T A V Sbjct 67 REANRLMEMITQLVDPQDPPKEQLWSALRGFFSFVSDHSGAWIVLYRQARTQGGPSAREV 126 Query 125 REGREQIVQLVAELVR--AGTRGPLTDAEIEMMAVALVGAGEAVAT-RLGIGDTDVDEAA 181 E R + V+L+A ++ AG R P A A ALVG+ E++A L T + A Sbjct 127 DEMRRRTVELIAAMLSQAAGMRKPGEQAVT--AAHALVGSCESLADWMLDTPGTSAETTA 184 Query 182 EMMINLFWLGLK 193 + +++ W GL+ Sbjct 185 KRLMHFAWPGLE 196 >gi|297201579|ref|ZP_06918976.1| TetR-family transcriptional regulator [Streptomyces sviceus ATCC 29083] gi|297147925|gb|EDY55084.2| TetR-family transcriptional regulator [Streptomyces sviceus ATCC 29083] Length=226 Score = 131 bits (329), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 77/195 (40%), Positives = 111/195 (57%), Gaps = 7/195 (3%) Query 5 TKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACL 64 +KR+PRAVREQQMLDAAV++F GY SMD IA A +SKP++YLY SKEDLF AC+ Sbjct 8 SKRMPRAVREQQMLDAAVEIFGQRGYMAASMDEIAELAGVSKPLVYLYLNSKEDLFTACI 67 Query 65 NREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQA-TSSQAFAHT 123 RE + +A+R+ + + L + +++F + + W V++ QA +AFA Sbjct 68 RREAAALTEAVRTGVRTELPADRQLWDGLLAFFTHTSQHPHGWSVLHLQARIHGEAFAAE 127 Query 124 VREGREQIVQLVAELV----RAGTRGP-LTDAEIEMMAVALVGAGEAVATRL-GIGDTDV 177 V RE+IV V L+ R R P L + E+ +A ALVGA E++A Sbjct 128 VTAMREEIVAFVTHLIVVAAREAHRDPDLPEREVAGLAEALVGAAESLAAWANATAGVTA 187 Query 178 DEAAEMMINLFWLGL 192 ++A ++N W GL Sbjct 188 RQSAATLMNFAWAGL 202 >gi|291445549|ref|ZP_06584939.1| TetR-family transcriptional regulator [Streptomyces roseosporus NRRL 15998] gi|291348496|gb|EFE75400.1| TetR-family transcriptional regulator [Streptomyces roseosporus NRRL 15998] Length=229 Score = 129 bits (325), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 77/196 (40%), Positives = 109/196 (56%), Gaps = 7/196 (3%) Query 5 TKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACL 64 +KR+PRAVREQQM+DAAV+ F GY SMD IA A +SKP++YLY SKEDLF AC+ Sbjct 21 SKRMPRAVREQQMMDAAVRTFGQRGYRAASMDEIAELAGVSKPLVYLYLNSKEDLFSACI 80 Query 65 NREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATS-SQAFAHT 123 RE ++A+R+ ++ L + +F + N +W V++ QA S + F Sbjct 81 RREAQSLLEAVRAGVDPGLPADAQLWAGLRAFFVHTAENPDAWSVLHRQARSHGEPFVSE 140 Query 124 VREGREQIVQLVAELVRAGTR-----GPLTDAEIEMMAVALVGAGEAVATRLG-IGDTDV 177 V R++IV V L+ A R L D ++ +A ALVGA E++A D Sbjct 141 VGSMRDEIVTFVTGLIGAAAREAHSDPALADRDVAGLAQALVGAAESLAGWANDTPDVSA 200 Query 178 DEAAEMMINLFWLGLK 193 EAA ++N W GL+ Sbjct 201 REAAATLMNFAWAGLE 216 Lambda K H 0.320 0.133 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 226797436674 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40