BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0254c

Length=174
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607395|ref|NP_214768.1|  bifunctional cobinamide kinase/cobi...   335    1e-90
gi|254366700|ref|ZP_04982744.1|  bifunctional cobalamin biosynthe...   335    2e-90
gi|289445787|ref|ZP_06435531.1|  bifunctional cobalamin biosynthe...   332    9e-90
gi|289764371|ref|ZP_06523749.1|  cobinamide kinase/cobinamide pho...   298    1e-79
gi|240167867|ref|ZP_04746526.1|  putative cobalamin biosynthesis ...   274    4e-72
gi|120401404|ref|YP_951233.1|  cobalbumin biosynthesis enzyme [My...   229    1e-58
gi|315442070|ref|YP_004074949.1|  adenosylcobinamide kinase [Myco...   229    2e-58
gi|145220959|ref|YP_001131637.1|  cobalbumin biosynthesis enzyme ...   223    1e-56
gi|319949247|ref|ZP_08023329.1|  cobalbumin biosynthesis enzyme [...   188    3e-46
gi|311743317|ref|ZP_07717124.1|  adenosylcobinamide-phosphate gua...   185    3e-45
gi|326333890|ref|ZP_08200122.1|  bifunctional adenosylcobalamin b...   182    1e-44
gi|302529228|ref|ZP_07281570.1|  adenosylcobinamide kinase [Strep...   168    3e-40
gi|258650437|ref|YP_003199593.1|  adenosylcobinamide-phosphategua...   167    6e-40
gi|119716736|ref|YP_923701.1|  adenosylcobinamide kinase [Nocardi...   162    2e-38
gi|226308845|ref|YP_002768805.1|  adenosyl cobinamide kinase/aden...   161    3e-38
gi|229488695|ref|ZP_04382561.1|  cobalbumin biosynthesis protein ...   160    5e-38
gi|300788875|ref|YP_003769166.1|  adenosylcobinamide kinase/adeno...   158    2e-37
gi|343925631|ref|ZP_08765148.1|  putative adenosyl cobinamide kin...   155    2e-36
gi|297626410|ref|YP_003688173.1|  CobU Bifunctional cobalamin bio...   153    9e-36
gi|336115959|ref|YP_004570725.1|  adenosyl cobinamide kinase/aden...   150    6e-35
gi|72161401|ref|YP_289058.1|  adenosylcobinamide kinase [Thermobi...   148    3e-34
gi|333918940|ref|YP_004492521.1|  adenosyl cobinamide kinase/aden...   145    2e-33
gi|333989072|ref|YP_004521686.1|  bifunctional cobalamin biosynth...   144    6e-33
gi|312141256|ref|YP_004008592.1|  adenosylcobinamide kinase/adeno...   143    1e-32
gi|340774242|gb|EGR96729.1|  adenosylcobinamide kinase/adenosylco...   143    1e-32
gi|284989184|ref|YP_003407738.1|  Adenosylcobinamide-phosphategua...   142    1e-32
gi|317125137|ref|YP_004099249.1|  adenosylcobinamide kinase [Intr...   142    2e-32
gi|314922249|gb|EFS86080.1|  nicotinate-nucleotide--dimethylbenzi...   142    2e-32
gi|282853506|ref|ZP_06262843.1|  nicotinate-nucleotide--dimethylb...   142    2e-32
gi|325673912|ref|ZP_08153602.1|  cobinamide kinase/cobinamide pho...   142    2e-32
gi|315078582|gb|EFT50613.1|  nicotinate-nucleotide--dimethylbenzi...   141    4e-32
gi|313772987|gb|EFS38953.1|  nicotinate-nucleotide--dimethylbenzi...   141    4e-32
gi|335051185|ref|ZP_08544118.1|  putative nicotinate-nucleotide--...   141    4e-32
gi|289426678|ref|ZP_06428407.1|  nicotinate-nucleotide--dimethylb...   141    4e-32
gi|327335022|gb|EGE76733.1|  nicotinate-nucleotide--dimethylbenzi...   141    4e-32
gi|313814375|gb|EFS52089.1|  nicotinate-nucleotide--dimethylbenzi...   141    4e-32
gi|342213584|ref|ZP_08706309.1|  nicotinate-nucleotide--dimethylb...   140    5e-32
gi|50841924|ref|YP_055151.1|  phosphoribosyltransferase, cobalami...   140    5e-32
gi|312199010|ref|YP_004019071.1|  cobalbumin biosynthesis protein...   140    5e-32
gi|314987188|gb|EFT31279.1|  nicotinate-nucleotide--dimethylbenzi...   140    5e-32
gi|145296161|ref|YP_001138982.1|  hypothetical protein cgR_2080 [...   140    9e-32
gi|313765462|gb|EFS36826.1|  nicotinate-nucleotide--dimethylbenzi...   139    1e-31
gi|313828657|gb|EFS66371.1|  nicotinate-nucleotide--dimethylbenzi...   139    1e-31
gi|19553401|ref|NP_601403.1|  adenosyl cobinamide kinase [Coryneb...   138    3e-31
gi|328908235|gb|EGG27994.1|  nicotinate-nucleotide--dimethylbenzi...   136    9e-31
gi|313835505|gb|EFS73219.1|  nicotinate-nucleotide--dimethylbenzi...   136    1e-30
gi|271964164|ref|YP_003338360.1|  adenosyl cobinamide kinase/aden...   136    1e-30
gi|118618849|ref|YP_907181.1|  bifunctional cobalamin biosynthesi...   134    4e-30
gi|343924156|ref|ZP_08763719.1|  adenosylcobinamide kinase/adenos...   134    6e-30
gi|183983242|ref|YP_001851533.1|  bifunctional cobalamin biosynth...   133    1e-29


>gi|15607395|ref|NP_214768.1| bifunctional cobinamide kinase/cobinamide phosphate guanylyltransferase 
[Mycobacterium tuberculosis H37Rv]
 gi|15839634|ref|NP_334671.1| cobinamide kinase/cobinamide phosphate guanylyltransferase [Mycobacterium 
tuberculosis CDC1551]
 gi|31791432|ref|NP_853925.1| putative bifunctional cobalamin biosynthesis protein cobU: cobinamide 
kinase + cobinamide phosphate guanylyltransferase [Mycobacterium 
bovis AF2122/97]
 74 more sequence titles
 Length=174

 Score =  335 bits (860),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 173/174 (99%), Positives = 174/174 (100%), Gaps = 0/174 (0%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT
Sbjct  1    MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG
Sbjct  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120

Query  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL
Sbjct  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174


>gi|254366700|ref|ZP_04982744.1| bifunctional cobalamin biosynthesis protein cobU : cobinamide 
kinase + cobinamide phosphate guanylyltransferase [Mycobacterium 
tuberculosis str. Haarlem]
 gi|134152212|gb|EBA44257.1| bifunctional cobalamin biosynthesis protein cobU : cobinamide 
kinase + cobinamide phosphate guanylyltransferase [Mycobacterium 
tuberculosis str. Haarlem]
Length=174

 Score =  335 bits (859),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 172/174 (99%), Positives = 174/174 (100%), Gaps = 0/174 (0%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT
Sbjct  1    MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG
Sbjct  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120

Query  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            LPTAIV+TNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL
Sbjct  121  LPTAIVMTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174


>gi|289445787|ref|ZP_06435531.1| bifunctional cobalamin biosynthesis protein cobU [Mycobacterium 
tuberculosis CPHL_A]
 gi|289418745|gb|EFD15946.1| bifunctional cobalamin biosynthesis protein cobU [Mycobacterium 
tuberculosis CPHL_A]
Length=174

 Score =  332 bits (852),  Expect = 9e-90, Method: Compositional matrix adjust.
 Identities = 172/174 (99%), Positives = 173/174 (99%), Gaps = 0/174 (0%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVAL RARRPPTWLT
Sbjct  1    MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALRRARRPPTWLT  60

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG
Sbjct  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120

Query  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL
Sbjct  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174


>gi|289764371|ref|ZP_06523749.1| cobinamide kinase/cobinamide phosphate guanylyltransferase [Mycobacterium 
tuberculosis GM 1503]
 gi|289711877|gb|EFD75893.1| cobinamide kinase/cobinamide phosphate guanylyltransferase [Mycobacterium 
tuberculosis GM 1503]
Length=154

 Score =  298 bits (764),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 153/154 (99%), Positives = 154/154 (100%), Gaps = 0/154 (0%)

Query  21   LGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVETADVATALSEARSPVLVD  80
            +GDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVETADVATALSEARSPVLVD
Sbjct  1    MGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVETADVATALSEARSPVLVD  60

Query  81   CLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHS  140
            CLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHS
Sbjct  61   CLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHS  120

Query  141  SGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            SGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL
Sbjct  121  SGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  154


>gi|240167867|ref|ZP_04746526.1| putative cobalamin biosynthesis protein [Mycobacterium kansasii 
ATCC 12478]
Length=174

 Score =  274 bits (700),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 136/174 (79%), Positives = 151/174 (87%), Gaps = 0/174 (0%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +RILVTGGVRSGKS HAEALL +A + VYVAPGR A G DPDWD+RVALHRARRPPTWLT
Sbjct  1    MRILVTGGVRSGKSMHAEALLANAIEAVYVAPGRRADGRDPDWDSRVALHRARRPPTWLT  60

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            +ETADVATALS  R PVLVDCLGTWLTA+MD EALW+  TA+ YA +E RLD LCAAL  
Sbjct  61   IETADVATALSNIRCPVLVDCLGTWLTALMDREALWNTTTAEAYAAVEERLDELCAALAE  120

Query  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            L  A+VVTNEVGLGVVP+H SG++FRDLLGTIN+RVA VCDEVHL+IAGRVLKL
Sbjct  121  LADAVVVTNEVGLGVVPAHRSGMMFRDLLGTINQRVANVCDEVHLLIAGRVLKL  174


>gi|120401404|ref|YP_951233.1| cobalbumin biosynthesis enzyme [Mycobacterium vanbaalenii PYR-1]
 gi|119954222|gb|ABM11227.1| adenosylcobinamide kinase [Mycobacterium vanbaalenii PYR-1]
Length=175

 Score =  229 bits (583),  Expect = 1e-58, Method: Compositional matrix adjust.
 Identities = 126/173 (73%), Positives = 139/173 (81%), Gaps = 1/173 (0%)

Query  3    ILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVE  62
            ILVTGGVRSGKS HAEALL DA  V Y+APGRPA GSDPDWDARVA HR RRP  W TVE
Sbjct  3    ILVTGGVRSGKSRHAEALLSDARQVTYLAPGRPADGSDPDWDARVAGHRTRRPAHWQTVE  62

Query  63   TADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGLP  122
            TADVA A+ +A   VLVDCLGTWLTA++D   LW   + +V+  ++ARL  LCAALT   
Sbjct  63   TADVAAAVRDADGAVLVDCLGTWLTAVLDRNNLWDKGSREVHDAVDARLTALCAALTARR  122

Query  123  TA-IVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
             A +VVTNEVGLGVVPSH SGVLFRDLLGT N+RVAAVCDEVHLVIAGRVLK+
Sbjct  123  EAVVVVTNEVGLGVVPSHRSGVLFRDLLGTANQRVAAVCDEVHLVIAGRVLKI  175


>gi|315442070|ref|YP_004074949.1| adenosylcobinamide kinase [Mycobacterium sp. Spyr1]
 gi|315260373|gb|ADT97114.1| adenosylcobinamide kinase [Mycobacterium sp. Spyr1]
Length=174

 Score =  229 bits (583),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 117/174 (68%), Positives = 132/174 (76%), Gaps = 0/174 (0%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +RILVTGGVRSGKS HAE LL  A  V YVAPGR   G+DPDWD R++ HRARRP  W T
Sbjct  1    MRILVTGGVRSGKSRHAEELLAGAGRVTYVAPGRAPDGTDPDWDDRISRHRARRPAHWQT  60

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
             ET+DVA A+ +A   VLVDCLGTWLTA++D   LW   +      +EAR+  LC AL G
Sbjct  61   TETSDVAAAVRDADGTVLVDCLGTWLTAVLDDNGLWDKGSRRAADEVEARVAALCDALAG  120

Query  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
             P A+VVTNEVGLGVVPSH SGVLFRDLLGT+N+RVA VCDEVHLVIAGRVL L
Sbjct  121  RPEAVVVTNEVGLGVVPSHRSGVLFRDLLGTVNQRVARVCDEVHLVIAGRVLTL  174


>gi|145220959|ref|YP_001131637.1| cobalbumin biosynthesis enzyme [Mycobacterium gilvum PYR-GCK]
 gi|145213445|gb|ABP42849.1| adenosylcobinamide kinase [Mycobacterium gilvum PYR-GCK]
Length=174

 Score =  223 bits (567),  Expect = 1e-56, Method: Compositional matrix adjust.
 Identities = 120/174 (69%), Positives = 135/174 (78%), Gaps = 0/174 (0%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +RILVTGGVRSGKS HAE LL  A  V YVAPGR A G+DPDWDARV+ HRARRP  W T
Sbjct  1    MRILVTGGVRSGKSRHAEELLAGAGHVTYVAPGRAADGTDPDWDARVSRHRARRPAHWRT  60

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            VETADVA A+ +A+  VLVDCLGTWLTA++D   LW   + +    +E R+  LC AL G
Sbjct  61   VETADVAVAVRDAQGTVLVDCLGTWLTAVLDDNGLWDKGSREATDEVEIRVTALCDALAG  120

Query  121  LPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
               A+VVTNEVGLGVVPSH SGVLFRDLLGT+N+RVA VCDEVHLVIAGRVL L
Sbjct  121  AAGAVVVTNEVGLGVVPSHRSGVLFRDLLGTVNQRVAQVCDEVHLVIAGRVLTL  174


>gi|319949247|ref|ZP_08023329.1| cobalbumin biosynthesis enzyme [Dietzia cinnamea P4]
 gi|319437088|gb|EFV92126.1| cobalbumin biosynthesis enzyme [Dietzia cinnamea P4]
Length=181

 Score =  188 bits (477),  Expect = 3e-46, Method: Compositional matrix adjust.
 Identities = 103/181 (57%), Positives = 122/181 (68%), Gaps = 7/181 (3%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAAD------VVYVAPGRPAAG-SDPDWDARVALHRAR  53
            +R+LVTGGVRSGKS HA  LL ++        V +VAPG PA    DPDW  RVA HRA 
Sbjct  1    MRVLVTGGVRSGKSRHAVRLLAESESTSGIDAVTFVAPGLPADELDDPDWAKRVAHHRAH  60

Query  54   RPPTWLTVETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDG  113
            RP +W TVE+ DVATA+ EA  PVLVDCLGTWLT  +D   LW A   +  A ++ RLD 
Sbjct  61   RPASWRTVESPDVATAVREAPGPVLVDCLGTWLTTTVDDLGLWDAPVDEARAAVDERLDV  120

Query  114  LCAALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLK  173
            LCA L      ++VTNEVG GVVP + SG +FRDLLG +N+ VA  CDEVHLV+ GRVL 
Sbjct  121  LCAVLEDRTDVVLVTNEVGSGVVPQYRSGAVFRDLLGALNQTVAECCDEVHLVVCGRVLT  180

Query  174  L  174
            L
Sbjct  181  L  181


>gi|311743317|ref|ZP_07717124.1| adenosylcobinamide-phosphate guanylyltransferase [Aeromicrobium 
marinum DSM 15272]
 gi|311313385|gb|EFQ83295.1| adenosylcobinamide-phosphate guanylyltransferase [Aeromicrobium 
marinum DSM 15272]
Length=179

 Score =  185 bits (469),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 105/177 (60%), Positives = 122/177 (69%), Gaps = 4/177 (2%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGS--DPDWDARVALHRARRPPTW  58
            V++LVTGGVRSGKS HAEALL     V YVAPG PAA +  DPDW ARV+ HR RRP  W
Sbjct  4    VKVLVTGGVRSGKSFHAEALLLAEPVVTYVAPG-PAADAVDDPDWAARVSAHRRRRPEHW  62

Query  59   LTVETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAAL  118
            LTVET D+  AL  A   VL+DCLGTW+TA +D    W A   D   V  ARLD    AL
Sbjct  63   LTVETHDLVAALDGAEGAVLIDCLGTWVTAQLDELDAWDALLEDWEPVFRARLDATAEAL  122

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
                 TA+VVTNEVG+GVVP+H SG +FRDLLGT N+R+A  CD+V LV+AGR + L
Sbjct  123  AAFRGTAVVVTNEVGMGVVPAHRSGRVFRDLLGTANQRIATECDQVLLVVAGRTITL  179


>gi|326333890|ref|ZP_08200122.1| bifunctional adenosylcobalamin biosynthesis protein CobU [Nocardioidaceae 
bacterium Broad-1]
 gi|325948296|gb|EGD40404.1| bifunctional adenosylcobalamin biosynthesis protein CobU [Nocardioidaceae 
bacterium Broad-1]
Length=179

 Score =  182 bits (462),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 107/179 (60%), Positives = 126/179 (71%), Gaps = 5/179 (2%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGS-DPDWDARVALHRARRPPTWL  59
            +RILVTGGVRSGKS HAE+LL  A  V YVAPG       DPDW AR+A H+ARRP  W 
Sbjct  1    MRILVTGGVRSGKSRHAESLLAAAPSVAYVAPGPTLEEEPDPDWAARLASHQARRPERWR  60

Query  60   TVETADVATALSEAR---SPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCA  116
            TVE+ D+A AL+E       V+VDCLGTWLTA+MD   LW A + +  A + A ++   A
Sbjct  61   TVESRDLAGALAEGLAAGDAVMVDCLGTWLTAVMDARGLWEATSEEATAAVSALVEEAAA  120

Query  117  ALTGLPTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
             L      +V VTNEVGLGVVP+H SG LFRDLLG +N+R+AA CDEVHLVIAGRVLKL
Sbjct  121  VLGDRNGDVVLVTNEVGLGVVPAHRSGRLFRDLLGLVNQRLAAACDEVHLVIAGRVLKL  179


>gi|302529228|ref|ZP_07281570.1| adenosylcobinamide kinase [Streptomyces sp. AA4]
 gi|302438123|gb|EFL09939.1| adenosylcobinamide kinase [Streptomyces sp. AA4]
Length=201

 Score =  168 bits (425),  Expect = 3e-40, Method: Compositional matrix adjust.
 Identities = 92/174 (53%), Positives = 117/174 (68%), Gaps = 2/174 (1%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            ++LV GGVRSGKS HAE L+     +VYVAPG P +  DP+W ARV  HRARRP  W TV
Sbjct  28   KVLVLGGVRSGKSRHAERLVAHHPHLVYVAPGLPPSAEDPEWAARVEAHRARRPRHWTTV  87

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET D+AT L  A SP+L+DCLGTWL+ ++D    WS +T+     L+ RL+   AA +  
Sbjct  88   ETTDLATVLRNATSPLLIDCLGTWLSRVLDEVGAWS-STSGWERRLDDRLEDFLAAWSQA  146

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
               +V V+NEVG GVVP+  SG LFRD+LG +N RV+A  D V L++AGR L L
Sbjct  147  RVPVVAVSNEVGSGVVPATVSGRLFRDVLGALNNRVSADSDRVSLIVAGRALDL  200


>gi|258650437|ref|YP_003199593.1| adenosylcobinamide-phosphateguanylyltransferase [Nakamurella 
multipartita DSM 44233]
 gi|258553662|gb|ACV76604.1| Adenosylcobinamide-phosphateguanylyltransferase [Nakamurella 
multipartita DSM 44233]
Length=180

 Score =  167 bits (423),  Expect = 6e-40, Method: Compositional matrix adjust.
 Identities = 93/175 (54%), Positives = 114/175 (66%), Gaps = 2/175 (1%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGR-PAAGSDPDWDARVALHRARRPPTWLT  60
            R LVTGGVRSGKS  AE LL D   V Y+APG  P    DP+W  R+  HRA+RP  W T
Sbjct  6    RTLVTGGVRSGKSRVAENLLADRPAVSYLAPGPVPDRSVDPEWADRIDAHRAQRPSHWRT  65

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            VET D+A AL + R+ VL+DCLGTW+TA++D    W    A+     + +LD L  A   
Sbjct  66   VETTDLARALGQERAAVLIDCLGTWVTAVVDQLGTWDRRLAEWQPDFDRQLDDLERAWRS  125

Query  121  LPTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
             P  +V VTNEVG GVVP H SG  FRDLLG +N+R+AA  D+V LV+AGR L+L
Sbjct  126  HPGPLVAVTNEVGWGVVPEHRSGRTFRDLLGRVNQRIAAASDDVLLVVAGRTLRL  180


>gi|119716736|ref|YP_923701.1| adenosylcobinamide kinase [Nocardioides sp. JS614]
 gi|119537397|gb|ABL82014.1| adenosylcobinamide kinase [Nocardioides sp. JS614]
Length=173

 Score =  162 bits (410),  Expect = 2e-38, Method: Compositional matrix adjust.
 Identities = 105/176 (60%), Positives = 121/176 (69%), Gaps = 5/176 (2%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +++LVTGGVRSGKSTHAEAL+     V YVAPG   A  D DW ARVA HRARRP TW T
Sbjct  1    MKVLVTGGVRSGKSTHAEALVRAEPAVTYVAPG--PAQDDADWAARVAAHRARRPATWTT  58

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            +ET D+A AL     PVLVDCLGTWLT  +D   LW A +  V A ++AR+      L G
Sbjct  59   LETGDLAAAL-RTPGPVLVDCLGTWLTRQVDEAGLWEAESDAVAAYVDARVSEALTVLAG  117

Query  121  LPTA--IVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
             P    ++VTNEVGLGVVP H SG LFRDLLG +N+R    CDEVHLV+AGRVL L
Sbjct  118  RPDGPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACDEVHLVVAGRVLVL  173


>gi|226308845|ref|YP_002768805.1| adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 
[Rhodococcus erythropolis PR4]
 gi|226187962|dbj|BAH36066.1| putative adenosyl cobinamide kinase/adenosyl cobinamide phosphate 
guanylyltransferase [Rhodococcus erythropolis PR4]
Length=440

 Score =  161 bits (407),  Expect = 3e-38, Method: Compositional matrix adjust.
 Identities = 96/174 (56%), Positives = 112/174 (65%), Gaps = 5/174 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R LVTGG RSGKST+AE LL     V Y+A G P    DPDW  R+A HRARRP TW TV
Sbjct  269  RTLVTGGARSGKSTYAEGLLAGYRHVTYIATGDPQ-DDDPDWIERIASHRARRPSTWTTV  327

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET+DV    + A +P+L+DCLGTWLTA +D    W  AT D+ AV  A +D L  A T  
Sbjct  328  ETSDVTEIFAAATTPILLDCLGTWLTARLDRHQAW--ATEDLSAV-HADIDRLADAWTAC  384

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            P  IV VTNEVG GVVP   SG LFRDLLG +N R+A+  + V L+ AG  L L
Sbjct  385  PVPIVAVTNEVGSGVVPDTKSGRLFRDLLGLVNSRIASESESVVLMTAGLPLSL  438


>gi|229488695|ref|ZP_04382561.1| cobalbumin biosynthesis protein [Rhodococcus erythropolis SK121]
 gi|229324199|gb|EEN89954.1| cobalbumin biosynthesis protein [Rhodococcus erythropolis SK121]
Length=440

 Score =  160 bits (406),  Expect = 5e-38, Method: Compositional matrix adjust.
 Identities = 96/174 (56%), Positives = 113/174 (65%), Gaps = 5/174 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R LVTGG RSGKST+AE LL     V Y+A G P    DPDW  R+A HRARRP TW TV
Sbjct  269  RTLVTGGARSGKSTYAEGLLAGYRHVTYIATGDPQ-DDDPDWIERIASHRARRPSTWTTV  327

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET++V   L+ A +P+L+DCLGTWLTA +D    W  AT D+ AV  A +D L  A T  
Sbjct  328  ETSEVTEILATATTPILLDCLGTWLTACLDRHRAW--ATEDLSAV-HADIDRLADAWTAC  384

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            P  IV VTNEVG GVVP   SG LFRDLLG +N R+A+  + V L+ AG  L L
Sbjct  385  PVPIVAVTNEVGSGVVPDTKSGRLFRDLLGLVNSRIASESESVVLMTAGLPLSL  438


>gi|300788875|ref|YP_003769166.1| adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 
[Amycolatopsis mediterranei U32]
 gi|299798389|gb|ADJ48764.1| adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 
[Amycolatopsis mediterranei U32]
 gi|340530499|gb|AEK45704.1| adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 
[Amycolatopsis mediterranei S699]
Length=213

 Score =  158 bits (400),  Expect = 2e-37, Method: Compositional matrix adjust.
 Identities = 88/173 (51%), Positives = 110/173 (64%), Gaps = 0/173 (0%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            ++LV GGVRSGKS HAE L+     +VYVAPG PA   DP+W ARVA H+ARRP  W TV
Sbjct  41   KVLVLGGVRSGKSRHAERLVAHHPHLVYVAPGLPAGEDDPEWAARVAAHQARRPANWKTV  100

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET D+A  L  A  P+L+DCLGTWL+ ++D    W       + + +   D L A     
Sbjct  101  ETTDLAGVLRAATEPLLIDCLGTWLSRVLDDVGAWRQKPGWEHRLDDRLEDFLAAWAAAR  160

Query  122  PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
               + V+NEVG GVVP+ SSG LFRD+LG +N RV+A  D V LV+AGR L L
Sbjct  161  VPVVAVSNEVGSGVVPATSSGRLFRDVLGALNNRVSADADRVVLVVAGRALDL  213


>gi|343925631|ref|ZP_08765148.1| putative adenosyl cobinamide kinase/adenosyl cobinamide phosphate 
guanylyltransferase [Gordonia alkanivorans NBRC 16433]
 gi|343764421|dbj|GAA12074.1| putative adenosyl cobinamide kinase/adenosyl cobinamide phosphate 
guanylyltransferase [Gordonia alkanivorans NBRC 16433]
Length=443

 Score =  155 bits (392),  Expect = 2e-36, Method: Compositional matrix adjust.
 Identities = 90/172 (53%), Positives = 110/172 (64%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            RI VTGG RSGKS +AE LL    DVVYVA G P AG DPDWD RV LHR RRP +W TV
Sbjct  273  RIFVTGGARSGKSRYAEGLLAGVDDVVYVAAGGPRAG-DPDWDRRVELHRERRPASWTTV  331

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            E  +VA  L  AR PVLVDCLGTWL A +D    W +   D    + + ++ L  A    
Sbjct  332  EDTEVAGVLRSARHPVLVDCLGTWLAARIDHHDAWESGELD---AVRSDVEDLLDAWRSC  388

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVL  172
            P  +V V+NEVG GVVP+ +SG LFRD LG +N  +A   D+V +++AG+ L
Sbjct  389  PVPVVAVSNEVGSGVVPATASGRLFRDELGRLNAEMADRADQVVMMVAGQPL  440


>gi|297626410|ref|YP_003688173.1| CobU Bifunctional cobalamin biosynthesis pyrophosphate enzyme 
[Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1]
 gi|46358054|dbj|BAD15279.1| bifunctional cobalamin biosynthesis protein [Propionibacterium 
freudenreichii subsp. shermanii]
 gi|296922175|emb|CBL56743.1| CobU Bifunctional cobalamin biosynthesis pyrophosphate enzyme 
[Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1]
Length=223

 Score =  153 bits (386),  Expect = 9e-36, Method: Compositional matrix adjust.
 Identities = 91/174 (53%), Positives = 108/174 (63%), Gaps = 3/174 (1%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R LVTGG RSGKS++AEALLG    V Y+A  +     DP+W AR+A H ARRP +W TV
Sbjct  32   RTLVTGGARSGKSSYAEALLGSFDHVDYIATSQ-RNPDDPEWMARIAAHVARRPKSWNTV  90

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET DVA  LS+  SP LVDCLG WLT  +D    W          L+ R+D L  A+ G 
Sbjct  91   ETLDVAQVLSDDGSPALVDCLGVWLTRELDVTDAWQHPE-QARPELQHRIDELATAVAGS  149

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            P  +V VTNEVG GVVP+  +G  FRD LG +N  VA  CDEV L +AGR L L
Sbjct  150  PRRVVLVTNEVGSGVVPATQAGRTFRDWLGILNASVADACDEVLLCVAGRALSL  203


>gi|336115959|ref|YP_004570725.1| adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 
[Microlunatus phosphovorus NM-1]
 gi|334683737|dbj|BAK33322.1| adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 
[Microlunatus phosphovorus NM-1]
Length=178

 Score =  150 bits (379),  Expect = 6e-35, Method: Compositional matrix adjust.
 Identities = 88/175 (51%), Positives = 109/175 (63%), Gaps = 3/175 (1%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGR-PAAGSDPDWDARVALHRARRPPT-WL  59
            RIL+TGGVRSGKS +AE LL   A+V YVA G  P   +DP+W AR+A HR RR P  W 
Sbjct  4    RILITGGVRSGKSAYAERLLSGGANVTYVATGPVPDPAADPEWAARIANHRDRRGPWGWT  63

Query  60   TVETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALT  119
            TVET D A+AL  A  PVL+DCLGTWLT+ +D    W    A+     + +      A  
Sbjct  64   TVETTDPASALRAADGPVLLDCLGTWLTSCLDELEAWQRPVAEWQPAWQEQSAEFVRAWR  123

Query  120  GLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
                 + VTNEVG GVVP H SG LF DLLG +N++VAA  D+V L++ GR + L
Sbjct  124  EA-DVVGVTNEVGWGVVPEHRSGRLFADLLGRLNQQVAAASDQVILMVMGRPITL  177


>gi|72161401|ref|YP_289058.1| adenosylcobinamide kinase [Thermobifida fusca YX]
 gi|71915133|gb|AAZ55035.1| adenosylcobinamide kinase [Thermobifida fusca YX]
Length=322

 Score =  148 bits (373),  Expect = 3e-34, Method: Compositional matrix adjust.
 Identities = 92/176 (53%), Positives = 110/176 (63%), Gaps = 3/176 (1%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGR-PAAGSDPDWDARVALHRARRPPTWLT  60
            R+LVTGG RSGKS+ AE  L    +V+YVA G  P   +D  W  RVA HR+RRP  W T
Sbjct  146  RVLVTGGARSGKSSEAELRLLGEPEVLYVATGPAPDPHADAAWAQRVAAHRSRRPAWWRT  205

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWS-AATADVYAVLEARLDGLCAAL-  118
            VET DVA  L++A   VL DC+GTWL  +M    +W+    AD    LE R+D L AA  
Sbjct  206  VETTDVAAVLAKADGAVLFDCVGTWLAHVMGECGMWADEVPADAEQRLEERIDALVAAWR  265

Query  119  TGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            T     + VTNEVG GVVP   SG LFRD LG +N+R+AA  +EV LV AGRVL L
Sbjct  266  TSAAYVVAVTNEVGSGVVPPTVSGGLFRDWLGRVNQRLAAESEEVVLVTAGRVLSL  321


>gi|333918940|ref|YP_004492521.1| adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 
[Amycolicicoccus subflavus DQS3-9A1]
 gi|333481161|gb|AEF39721.1| Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 
[Amycolicicoccus subflavus DQS3-9A1]
Length=177

 Score =  145 bits (366),  Expect = 2e-33, Method: Compositional matrix adjust.
 Identities = 84/178 (48%), Positives = 112/178 (63%), Gaps = 9/178 (5%)

Query  2    RILVTGGVRSGKSTHAEALL----GDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPT  57
            R+LV GG RSGKS H+E L+       ++V Y+A   P   +DP+W+ R+A+HRARR P 
Sbjct  3    RVLVLGGARSGKSGHSEELIAVMANSPSEVRYIATSPPRV-NDPEWEERIAVHRARRAPQ  61

Query  58   WLTVETADVATALSEARS-PVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCA  116
            W TVETADVA  L   R+ P LVD LGTWLTA +D    W    A +  VL+  +  +CA
Sbjct  62   WHTVETADVAMELRRERAVPTLVDDLGTWLTAQIDARQAWDGGPAALDDVLDDLVSAVCA  121

Query  117  ALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
                L   ++VT EVG+G+VP   SG +FRDL+G +N R+A  C++V +VIAG  L L
Sbjct  122  YEGPL---VIVTPEVGMGIVPPTRSGRMFRDLIGVLNSRLAEKCEKVVVVIAGIPLPL  176


>gi|333989072|ref|YP_004521686.1| bifunctional cobalamin biosynthesis protein CobU [Mycobacterium 
sp. JDM601]
 gi|333485041|gb|AEF34433.1| bifunctional cobalamin biosynthesis protein CobU [Mycobacterium 
sp. JDM601]
Length=445

 Score =  144 bits (362),  Expect = 6e-33, Method: Compositional matrix adjust.
 Identities = 91/175 (52%), Positives = 113/175 (65%), Gaps = 5/175 (2%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
             R LV GG RSGKS HAEALL   + V Y+A G    G DP+W  RV LHRARRP +W T
Sbjct  272  TRTLVLGGARSGKSAHAEALLAAESAVTYLATGGVREG-DPEWAERVRLHRARRPASWRT  330

Query  61   VETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            +E +D A  L  A +P+L+DCLGTWLTA MD   +W     D    +   +D L AA   
Sbjct  331  IEGSDAAEQLRTAENPLLLDCLGTWLTARMDLHGVWDGGALD---GVHGDIDELLAAWRA  387

Query  121  LPT-AIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
             P  A+ V+NEVG GVVP+ +SG LFRDLLG +N R+AA  D+V L++AGR L+L
Sbjct  388  CPARAVAVSNEVGSGVVPATASGRLFRDLLGVLNARIAAESDDVVLMVAGRPLRL  442


>gi|312141256|ref|YP_004008592.1| adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase 
[Rhodococcus equi 103S]
 gi|311890595|emb|CBH49913.1| putative adenosylcobinamide kinase/adenosylcobinamide phosphate 
guanylyltransferase [Rhodococcus equi 103S]
Length=429

 Score =  143 bits (360),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 86/169 (51%), Positives = 108/169 (64%), Gaps = 5/169 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R LV GG R+GKST+AEALL     V Y+A G    G D +W  R+ALHRARRPP W TV
Sbjct  259  RTLVLGGARAGKSTYAEALLAAEPRVTYLATGGVREG-DREWAQRIALHRARRPPGWTTV  317

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET++VA AL  AR PVL+DCLGTWLTA +D   +W+      +  ++A +  L  AL   
Sbjct  318  ETSNVAQALRNAREPVLLDCLGTWLTARLDHHGVWTGGD---WTAVDADVTDLLGALRRA  374

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
               +V V+NEVG GVVP   +G  FRDLLG +N  VAA  + V L++AG
Sbjct  375  TVPVVAVSNEVGSGVVPPTPAGRRFRDLLGRVNSAVAAESESVVLMVAG  423


>gi|340774242|gb|EGR96729.1| adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase 
[Propionibacterium acnes SK182B-JCVI]
Length=223

 Score =  143 bits (360),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 109/172 (64%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW T+
Sbjct  47   RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DTEWEERIRLHQARRPATWRTI  105

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D   +  L +R+D L  A+
Sbjct  106  ETIDIASVLLADDDSPVLVDCLGVWITRILDEVGAWTAAAEDETWHNDLRSRVDELTGAI  165

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
                   I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  166  RRTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGDACDEVWMCVAG  217


>gi|284989184|ref|YP_003407738.1| Adenosylcobinamide-phosphateguanylyltransferase [Geodermatophilus 
obscurus DSM 43160]
 gi|284062429|gb|ADB73367.1| Adenosylcobinamide-phosphateguanylyltransferase [Geodermatophilus 
obscurus DSM 43160]
Length=173

 Score =  142 bits (359),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 87/174 (50%), Positives = 106/174 (61%), Gaps = 5/174 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKS HAEALL DA DV Y+A   P  G D +W  RVA HRARRPP W T+
Sbjct  3    RVLVLGGSRSGKSAHAEALLADAGDVTYLATAPPVPG-DAEWAERVAAHRARRPPGWTTL  61

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET   +  L   R  VLVD + TW+ A+MD   +W+         L  R D L  A T  
Sbjct  62   ETTAPSDLLR--RGTVLVDSVTTWVAALMDETGVWTDEPG-ARDRLARRCDALVEAWTTT  118

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            P  +V V++EVGLGVVP   SG LFRD LG++N+R+A   DEV  V+AG   +L
Sbjct  119  PAHVVAVSDEVGLGVVPETRSGRLFRDTLGSVNQRLAGTADEVWFVVAGLPQRL  172


>gi|317125137|ref|YP_004099249.1| adenosylcobinamide kinase [Intrasporangium calvum DSM 43043]
 gi|315589225|gb|ADU48522.1| adenosylcobinamide kinase [Intrasporangium calvum DSM 43043]
Length=196

 Score =  142 bits (358),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 87/173 (51%), Positives = 107/173 (62%), Gaps = 5/173 (2%)

Query  4    LVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTVET  63
            LVTG VRSGKS HAE L+    DV+YVA GRP+   D  W  RV  H+ RRP +W T+ET
Sbjct  10   LVTGPVRSGKSRHAEDLVALHQDVLYVATGRPSDQDDSAWAERVRAHQRRRPDSWRTLET  69

Query  64   ADVATALSEARSPVLVDCLGTWLTAIMD--GEALWSAATADVYAVLEARLDGLCAALTGL  121
             D+  AL+ A  PVL+DCLGTWLT  +D  G      A   V     + ++ LC A   +
Sbjct  70   VDLDAALAGASGPVLIDCLGTWLTGQVDLVGWEDLDRAAQHVRERSVSLVESLCRASHPV  129

Query  122  PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
               +VVTNEVG  +VP+  SG LF+D LG +N RVA V   VHLV+AGRVL L
Sbjct  130  ---VVVTNEVGWSLVPTTPSGRLFQDELGRLNARVAEVATAVHLVVAGRVLDL  179


>gi|314922249|gb|EFS86080.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL001PA1]
 gi|314965141|gb|EFT09240.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL082PA2]
 gi|314982420|gb|EFT26513.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL110PA3]
 gi|315090589|gb|EFT62565.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL110PA4]
 gi|315094089|gb|EFT66065.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL060PA1]
 gi|315104528|gb|EFT76504.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL050PA2]
 gi|327329428|gb|EGE71188.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL103PA1]
Length=556

 Score =  142 bits (358),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 84/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   +D L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQDDLRRHVDDLTSAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|282853506|ref|ZP_06262843.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes J139]
 gi|282582959|gb|EFB88339.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes J139]
Length=555

 Score =  142 bits (358),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 84/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  379  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  437

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   +D L +A+
Sbjct  438  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQDDLRRHVDDLTSAI  497

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  498  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  549


>gi|325673912|ref|ZP_08153602.1| cobinamide kinase/cobinamide phosphate guanylyltransferase [Rhodococcus 
equi ATCC 33707]
 gi|325555177|gb|EGD24849.1| cobinamide kinase/cobinamide phosphate guanylyltransferase [Rhodococcus 
equi ATCC 33707]
Length=429

 Score =  142 bits (358),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 86/169 (51%), Positives = 107/169 (64%), Gaps = 5/169 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R LV GG R+GKST+AEALL     V Y+A G    G D +W  R+ALHRARRPP W TV
Sbjct  259  RTLVLGGARAGKSTYAEALLVAEPRVTYLATGGVREG-DREWAQRIALHRARRPPGWTTV  317

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET+DVA  L  AR PVL+DCLGTWLTA +D   +W+      +  ++A +  L  AL   
Sbjct  318  ETSDVAPTLRNAREPVLLDCLGTWLTARLDHHGVWTGGD---WTAVDADITDLLGALRRA  374

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
               +V V+NEVG GVVP   +G  FRDLLG +N  VAA  + V L++AG
Sbjct  375  TVPVVAVSNEVGSGVVPPTPAGRRFRDLLGKVNSAVAAESESVVLMVAG  423


>gi|315078582|gb|EFT50613.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL053PA2]
Length=556

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|313772987|gb|EFS38953.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL074PA1]
 gi|313792988|gb|EFS41055.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL110PA1]
 gi|313802563|gb|EFS43785.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL110PA2]
 31 more sequence titles
 Length=556

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|335051185|ref|ZP_08544118.1| putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium sp. 409-HC1]
 gi|333767699|gb|EGL44927.1| putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium sp. 409-HC1]
Length=348

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  172  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  230

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  231  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  290

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  291  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  342


>gi|289426678|ref|ZP_06428407.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes J165]
 gi|289160173|gb|EFD08348.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes J165]
Length=555

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  379  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  437

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  438  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  497

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  498  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  549


>gi|327335022|gb|EGE76733.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL097PA1]
Length=556

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|313814375|gb|EFS52089.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL025PA1]
Length=556

 Score =  141 bits (355),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|342213584|ref|ZP_08706309.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium sp. CC003-HC2]
 gi|340769128|gb|EGR91653.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium sp. CC003-HC2]
Length=555

 Score =  140 bits (354),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  379  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  437

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  438  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  497

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  498  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  549


>gi|50841924|ref|YP_055151.1| phosphoribosyltransferase, cobalamin biosynthesis enzyme, fusion 
CobTU [Propionibacterium acnes KPA171202]
 gi|289424649|ref|ZP_06426432.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes SK187]
 gi|295129995|ref|YP_003580658.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes SK137]
 7 more sequence titles
 Length=555

 Score =  140 bits (354),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  379  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  437

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  438  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  497

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  498  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  549


>gi|312199010|ref|YP_004019071.1| cobalbumin biosynthesis protein [Frankia sp. EuI1c]
 gi|311230346|gb|ADP83201.1| cobalbumin biosynthesis protein [Frankia sp. EuI1c]
Length=207

 Score =  140 bits (354),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 94/185 (51%), Positives = 111/185 (60%), Gaps = 12/185 (6%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+L+TGG RSGKS  AE +L   A VVY+A G      DP+W ARVA H+ARRP +W TV
Sbjct  22   RVLITGGARSGKSQLAEDMLAGRAQVVYLATGAVPTADDPEWSARVATHQARRPASWTTV  81

Query  62   ETADVATALS---EARSP--VLVDCLGTWLTAIMDGEALWSAATAD------VYAVLEAR  110
            ETAD A  L+    A  P  VL DC+GTWLTA MD   +W+A  A         A L   
Sbjct  82   ETADAAGILAADPAAAGPRAVLFDCVGTWLTAAMDASGIWAADEAGGTVATTADAALAQA  141

Query  111  LDGLCAALTGLPTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             D L AA  G    +V VTNEVG GVVP+  SG  FRD LG +N R+AAV DEV L  AG
Sbjct  142  QDRLVAAWAGTTADVVAVTNEVGSGVVPATRSGRRFRDELGRLNTRLAAVADEVWLCTAG  201

Query  170  RVLKL  174
              L++
Sbjct  202  IPLRI  206


>gi|314987188|gb|EFT31279.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL005PA2]
 gi|314988919|gb|EFT33010.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL005PA3]
Length=556

 Score =  140 bits (354),  Expect = 5e-32, Method: Compositional matrix adjust.
 Identities = 83/172 (49%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLVDCLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVDCLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|145296161|ref|YP_001138982.1| hypothetical protein cgR_2080 [Corynebacterium glutamicum R]
 gi|140846081|dbj|BAF55080.1| hypothetical protein [Corynebacterium glutamicum R]
Length=174

 Score =  140 bits (352),  Expect = 9e-32, Method: Compositional matrix adjust.
 Identities = 84/177 (48%), Positives = 115/177 (65%), Gaps = 9/177 (5%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +R LV GG RSGKS  AE+L+G    V+YVA  RP+ G DP++  R+A+H ARRP +W+ 
Sbjct  1    MRTLVLGGARSGKSAFAESLVG-CGPVLYVATARPS-GDDPEFAERIAVHAARRPTSWVL  58

Query  61   VETADVATALSEARS-PVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALT  119
             E  DV   L+   + PVLVD LGTWLT   D    W A++A     LEA++D L  A+ 
Sbjct  59   DEEGDVDKLLASPPAIPVLVDDLGTWLTHATDACDGWEASSAQ----LEAKMDLLIDAIL  114

Query  120  GLPTA--IVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
                A  ++V+ EVG+G+VP + SG LFRD +GT+N+RVAA+C+ V  V+AG  L+L
Sbjct  115  HFQGADLVIVSPEVGMGIVPEYKSGRLFRDRIGTLNQRVAAICERVVFVVAGLPLEL  171


>gi|313765462|gb|EFS36826.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL013PA1]
 gi|313815134|gb|EFS52848.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL059PA1]
 gi|314915893|gb|EFS79724.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL005PA4]
 13 more sequence titles
 Length=556

 Score =  139 bits (351),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 82/172 (48%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLV+CLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVECLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|313828657|gb|EFS66371.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL063PA2]
Length=556

 Score =  139 bits (351),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 82/172 (48%), Positives = 108/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R+LV GG RSGKST AE+ L   + V YVA  +   G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RMLVIGGARSGKSTFAESRLPRDSRVTYVATSQRNPG-DAEWEERIRLHQARRPATWQTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SPVLV+CLG W+T I+D    W+AA  D      L   ++ L +A+
Sbjct  439  ETTDIASVLLADDDSPVLVECLGVWITRILDEVGAWAAAPGDEAWQNDLRRHVNDLASAI  498

Query  119  TGLP-TAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
             G     I V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RGTRRDVIFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGEACDEVWMCVAG  550


>gi|19553401|ref|NP_601403.1| adenosyl cobinamide kinase [Corynebacterium glutamicum ATCC 13032]
 gi|62391039|ref|YP_226441.1| cobinamide kinase / cobinamide phosphate guanylyltransferase 
[Corynebacterium glutamicum ATCC 13032]
 gi|21324969|dbj|BAB99592.1| Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 
[Corynebacterium glutamicum ATCC 13032]
 gi|41326378|emb|CAF20540.1| COBINAMIDE KINASE / COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE 
[Corynebacterium glutamicum ATCC 13032]
 gi|344044869|gb|EGV40544.1| cobinamide kinase / cobinamide phosphate guanylyltransferase 
[Corynebacterium glutamicum S9114]
Length=174

 Score =  138 bits (347),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 83/177 (47%), Positives = 113/177 (64%), Gaps = 9/177 (5%)

Query  1    VRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLT  60
            +R LV GG RSGKS  AE+L+G +  V+YVA  RP+ G DP++  R+A+H  RRP +W+ 
Sbjct  1    MRTLVLGGARSGKSAFAESLVG-SGPVLYVATARPS-GDDPEFAERIAVHAERRPTSWVL  58

Query  61   VETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALT  119
             E  DV   L S    PVLVD LGTWLT   D    W A++A     LEA++D L  A+ 
Sbjct  59   DEEGDVDKLLASPPAMPVLVDDLGTWLTHATDACDGWEASSAQ----LEAKMDLLIDAIL  114

Query  120  GLPTA--IVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
                   ++V+ EVG+G+VP + SG LFRD +GT+N+RVAA+C+ V  V+AG  L+L
Sbjct  115  HFQGEDLVIVSPEVGMGIVPEYKSGRLFRDRIGTLNQRVAAICERVVFVVAGLPLEL  171


>gi|328908235|gb|EGG27994.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium humerusii P08]
Length=555

 Score =  136 bits (343),  Expect = 9e-31, Method: Compositional matrix adjust.
 Identities = 80/172 (47%), Positives = 107/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R L+ GG RSGKST AE+ L   + V YVA  +  +G D +W+ R+ LH+ARRP TW TV
Sbjct  379  RALILGGARSGKSTFAESRLPRDSCVTYVATSQRNSG-DAEWEERIRLHQARRPATWHTV  437

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SP+LVDCLG W+T I+D    W+AA  D      L+  +D L  A+
Sbjct  438  ETTDIASVLLADDESPMLVDCLGVWMTRILDEVGAWTAAPGDQTWQNDLKGHVDELTDAI  497

Query  119  TGLPTAI-VVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
                  +  V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  498  RRTRRDVTFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGQACDEVWMCVAG  549


>gi|313835505|gb|EFS73219.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL037PA2]
 gi|314928617|gb|EFS92448.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL044PA1]
 gi|314970420|gb|EFT14518.1| nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 
[Propionibacterium acnes HL037PA3]
Length=556

 Score =  136 bits (343),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 80/172 (47%), Positives = 107/172 (63%), Gaps = 5/172 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R L+ GG RSGKST AE+ L   + V YVA  +  +G D +W+ R+ LH+ARRP TW TV
Sbjct  380  RALILGGARSGKSTFAESRLPRDSCVTYVATSQRNSG-DAEWEERIRLHQARRPATWHTV  438

Query  62   ETADVATAL-SEARSPVLVDCLGTWLTAIMDGEALWSAATADV--YAVLEARLDGLCAAL  118
            ET D+A+ L ++  SP+LVDCLG W+T I+D    W+AA  D      L+  +D L  A+
Sbjct  439  ETTDIASVLLADDESPMLVDCLGVWMTRILDEVGAWTAAPGDQTWQNDLKGHVDELTDAI  498

Query  119  TGLPTAI-VVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAG  169
                  +  V+NEVG+GVVP   +G LFRD LG +N  V   CDEV + +AG
Sbjct  499  RRTRRDVTFVSNEVGMGVVPDTPAGRLFRDELGRLNAAVGQACDEVWMCVAG  550


>gi|271964164|ref|YP_003338360.1| adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase-like 
protein [Streptosporangium roseum DSM 43021]
 gi|270507339|gb|ACZ85617.1| Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase-like 
protein [Streptosporangium roseum DSM 43021]
Length=402

 Score =  136 bits (342),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 83/174 (48%), Positives = 108/174 (63%), Gaps = 4/174 (2%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R L+ GG RSGKS  AE  L    +V+YVA G P+ G D +W  RV  HR RRP  W T 
Sbjct  230  RTLLLGGTRSGKSAEAELRLAGEPEVLYVATG-PSGGDDDEWTRRVQTHRDRRPAHWGTA  288

Query  62   ETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTGL  121
            ET D+A  L  A +P+L+D LGTW+ A+ D    WS    D    + AR D L AA    
Sbjct  289  ETTDLAGLLRTAEAPMLIDGLGTWVAAVFDECDAWSG--GDGRDAVTARCDELVAAWRQA  346

Query  122  PTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
               +V V++EVGLGVVP+ SSG +FRD+LG +N+R+A   ++V LV+AGR+L L
Sbjct  347  RAQVVAVSDEVGLGVVPATSSGRMFRDVLGRLNQRLALESEDVALVVAGRLLPL  400


>gi|118618849|ref|YP_907181.1| bifunctional cobalamin biosynthesis protein CobU [Mycobacterium 
ulcerans Agy99]
 gi|118570959|gb|ABL05710.1| bifunctional cobalamin biosynthesis protein CobU [Mycobacterium 
ulcerans Agy99]
Length=186

 Score =  134 bits (338),  Expect = 4e-30, Method: Compositional matrix adjust.
 Identities = 86/184 (47%), Positives = 113/184 (62%), Gaps = 13/184 (7%)

Query  1    VRILVTGGVRSGKSTHAEALLGDA----ADVVYVAPGRPAAGSD----PDWDARVALHRA  52
            +R LV GG+RSGKS  AE  + D+      V Y+A G PA  SD     DWD RVA HR 
Sbjct  1    MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASG-PATDSDSAASQDWDQRVARHRD  59

Query  53   RRPPTWLTVETADVATALSE-ARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARL  111
            RRP  W TVET D+AT L +   +P LVD LGTWLT+ MD    W   +    A L+  +
Sbjct  60   RRPGHWSTVETDDIATQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSP--PAALQDTI  117

Query  112  DGLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGR  170
            D + AA+     T ++V+ EVGL VVP+ +SG  F D LGT+N+R+AA+CD V LV+AG+
Sbjct  118  DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ  177

Query  171  VLKL  174
             + +
Sbjct  178  AVPI  181


>gi|343924156|ref|ZP_08763719.1| adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase/nicotinate-nucleotide--dimethylbenzimidazole 
phosphoribosyltransferase 
[Gordonia alkanivorans NBRC 16433]
 gi|343765961|dbj|GAA10645.1| adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase/nicotinate-nucleotide--dimethylbenzimidazole 
phosphoribosyltransferase 
[Gordonia alkanivorans NBRC 16433]
Length=592

 Score =  134 bits (336),  Expect = 6e-30, Method: Compositional matrix adjust.
 Identities = 83/175 (48%), Positives = 107/175 (62%), Gaps = 6/175 (3%)

Query  2    RILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWDARVALHRARRPPTWLTV  61
            R LV GGVRSGKS H E+LL     + Y+A G P   SD +W ARV  HR RR   + T+
Sbjct  7    RTLVLGGVRSGKSAHGESLLRAHQQIRYLATG-PVTTSDAEWTARVNTHRQRRDARYTTI  65

Query  62   ETADVATALSEARS-PVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARLDGLCAALTG  120
            ET D+A AL  A   P LVD LG+WLTA +D    W + +      L+A +  LC +L  
Sbjct  66   ETTDLAEALRAAPDIPALVDDLGSWLTARIDAVDGWESGSG---IDLDADITELCDSLRA  122

Query  121  LPTAIV-VTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGRVLKL  174
            +   +V +++EVGL +VP   +G LF+DLLGT+N  VA  CD V LV+AGRVL L
Sbjct  123  MNADVVLISSEVGLSLVPPTPAGRLFQDLLGTLNSAVAQACDRVSLVVAGRVLDL  177


>gi|183983242|ref|YP_001851533.1| bifunctional cobalamin biosynthesis protein CobU [Mycobacterium 
marinum M]
 gi|183176568|gb|ACC41678.1| bifunctional cobalamin biosynthesis protein CobU [Mycobacterium 
marinum M]
Length=186

 Score =  133 bits (334),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 85/184 (47%), Positives = 112/184 (61%), Gaps = 13/184 (7%)

Query  1    VRILVTGGVRSGKSTHAEALLGDA----ADVVYVAPGRPAAGSD----PDWDARVALHRA  52
            +R LV GG+RSGKS  AE  + D+      V Y+A G PA  SD     DWD RVA HR 
Sbjct  1    MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASG-PATDSDSAASQDWDQRVARHRD  59

Query  53   RRPPTWLTVETADVATALSE-ARSPVLVDCLGTWLTAIMDGEALWSAATADVYAVLEARL  111
            RRP  W TVET D+ T L +   +P LVD LGTWLT+ MD    W   +    A L+  +
Sbjct  60   RRPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSP--PAALQDTI  117

Query  112  DGLCAALTGL-PTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVCDEVHLVIAGR  170
            D + AA+     T ++V+ EVGL VVP+ +SG  F D LGT+N+R+AA+CD V LV+AG+
Sbjct  118  DDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQ  177

Query  171  VLKL  174
             + +
Sbjct  178  AVPI  181



Lambda     K      H
   0.320    0.135    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 142560794112




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40