BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0255c Length=494 Score E Sequences producing significant alignments: (Bits) Value gi|15839635|ref|NP_334672.1| cobyric acid synthase [Mycobacteriu... 971 0.0 gi|289572834|ref|ZP_06453061.1| cobyric acid synthase cobQ1 [Myc... 971 0.0 gi|289748738|ref|ZP_06508116.1| cobyric acid synthase cobQ1 [Myc... 970 0.0 gi|340625293|ref|YP_004743745.1| putative cobyric acid synthase ... 953 0.0 gi|308370352|ref|ZP_07421199.2| cobyric acid synthase cobQ1 [Myc... 939 0.0 gi|118619015|ref|YP_907347.1| cobyric acid synthase [Mycobacteri... 832 0.0 gi|183983813|ref|YP_001852104.1| cobyric acid synthase CobQ1 [My... 829 0.0 gi|145220964|ref|YP_001131642.1| cobyric acid synthase [Mycobact... 778 0.0 gi|315442065|ref|YP_004074944.1| adenosylcobyric acid synthase (... 759 0.0 gi|120401402|ref|YP_951231.1| cobyric acid synthase [Mycobacteri... 737 0.0 gi|326333066|ref|ZP_08199317.1| cobyric acid synthase CobQ [Noca... 715 0.0 gi|333991818|ref|YP_004524432.1| cobyric acid synthase CobQ1 [My... 701 0.0 gi|298523723|ref|ZP_07011132.1| cobyric acid synthase [Mycobacte... 701 0.0 gi|297560574|ref|YP_003679548.1| cobyric acid synthase CobQ [Noc... 673 0.0 gi|119716735|ref|YP_923700.1| cobyric acid synthase [Nocardioide... 647 0.0 gi|119717104|ref|YP_924069.1| cobyric acid synthase [Nocardioide... 647 0.0 gi|257055791|ref|YP_003133623.1| cobyric acid synthase [Saccharo... 622 4e-176 gi|319948916|ref|ZP_08023025.1| cobyric acid synthase [Dietzia c... 592 7e-167 gi|311744336|ref|ZP_07718138.1| cobyric acid synthase CobQ [Aero... 549 3e-154 gi|284031614|ref|YP_003381545.1| cobyric acid synthase CobQ [Kri... 536 4e-150 gi|300788873|ref|YP_003769164.1| adenosylcobyric acid synthase [... 528 1e-147 gi|72160713|ref|YP_288370.1| cobyric acid synthase [Thermobifida... 509 4e-142 gi|302529226|ref|ZP_07281568.1| cobyric acid synthase CobQ [Stre... 504 2e-140 gi|238060673|ref|ZP_04605382.1| cobyric acid synthase cobQ [Micr... 499 4e-139 gi|330469709|ref|YP_004407452.1| cobyric acid synthase CobQ [Ver... 498 1e-138 gi|256395157|ref|YP_003116721.1| cobyric acid synthase CobQ [Cat... 493 2e-137 gi|159039457|ref|YP_001538710.1| cobyric acid synthase CobQ [Sal... 491 1e-136 gi|302869419|ref|YP_003838056.1| cobyric acid synthase CobQ [Mic... 490 2e-136 gi|269125539|ref|YP_003298909.1| cobyric acid synthase CobQ [The... 489 4e-136 gi|258650404|ref|YP_003199560.1| cobyric acid synthase [Nakamure... 486 4e-135 gi|284989156|ref|YP_003407710.1| cobyric acid synthase CobQ [Geo... 482 5e-134 gi|271968632|ref|YP_003342828.1| adenosylcobyric acid synthase [... 482 5e-134 gi|340774431|gb|EGR96918.1| cobyric acid synthase CobQ [Propioni... 480 2e-133 gi|315504103|ref|YP_004082990.1| cobyric acid synthase cobq [Mic... 479 5e-133 gi|145596066|ref|YP_001160363.1| cobyric acid synthase CobQ [Sal... 477 3e-132 gi|312194369|ref|YP_004014430.1| cobyric acid synthase CobQ [Fra... 476 6e-132 gi|317123947|ref|YP_004098059.1| adenosylcobyric acid synthase (... 471 1e-130 gi|294628671|ref|ZP_06707231.1| cobyric acid synthase CobQ [Stre... 470 2e-130 gi|288918655|ref|ZP_06413003.1| cobyric acid synthase CobQ [Fran... 470 2e-130 gi|297198773|ref|ZP_06916170.1| cobyric acid synthase CobQ [Stre... 470 3e-130 gi|302561367|ref|ZP_07313709.1| cobyric acid synthase CobQ [Stre... 469 4e-130 gi|302550524|ref|ZP_07302866.1| cobyric acid synthase CobQ [Stre... 467 2e-129 gi|289772432|ref|ZP_06531810.1| cobyric acid synthase CobQ [Stre... 466 4e-129 gi|311899006|dbj|BAJ31414.1| putative cobyric acid synthase [Kit... 466 5e-129 gi|328881543|emb|CCA54782.1| Cobyric acid synthase [Streptomyces... 465 8e-129 gi|290961437|ref|YP_003492619.1| cobyric acid synthase [Streptom... 465 8e-129 gi|134102427|ref|YP_001108088.1| cobyric acid synthase [Saccharo... 464 1e-128 gi|336116044|ref|YP_004570810.1| cobyric acid synthase [Microlun... 464 1e-128 gi|329940747|ref|ZP_08290027.1| cobyric acid synthase [Streptomy... 463 3e-128 gi|296139407|ref|YP_003646650.1| cobyric acid synthase CobQ [Tsu... 462 5e-128 >gi|15839635|ref|NP_334672.1| cobyric acid synthase [Mycobacterium tuberculosis CDC1551] gi|31791433|ref|NP_853926.1| cobyric acid synthase [Mycobacterium bovis AF2122/97] gi|57116707|ref|YP_177703.1| cobyric acid synthase [Mycobacterium tuberculosis H37Rv] 61 more sequence titles Length=494 Score = 971 bits (2511), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/494 (100%), Positives = 494/494 (100%), Gaps = 0/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR Sbjct 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR Sbjct 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG Sbjct 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA Sbjct 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG Sbjct 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV Sbjct 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG Sbjct 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH Sbjct 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 Query 481 GCPPTLPFLAPGAP 494 GCPPTLPFLAPGAP Sbjct 481 GCPPTLPFLAPGAP 494 >gi|289572834|ref|ZP_06453061.1| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis K85] gi|289537265|gb|EFD41843.1| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis K85] Length=494 Score = 971 bits (2509), Expect = 0.0, Method: Compositional matrix adjust. Identities = 493/494 (99%), Positives = 494/494 (100%), Gaps = 0/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR Sbjct 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR Sbjct 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG Sbjct 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA Sbjct 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG Sbjct 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLRARDLDRALL+HVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV Sbjct 301 TRATIADLAWLRARDLDRALLLHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG Sbjct 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH Sbjct 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 Query 481 GCPPTLPFLAPGAP 494 GCPPTLPFLAPGAP Sbjct 481 GCPPTLPFLAPGAP 494 >gi|289748738|ref|ZP_06508116.1| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis T92] gi|289689325|gb|EFD56754.1| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis T92] Length=494 Score = 970 bits (2508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 493/494 (99%), Positives = 493/494 (99%), Gaps = 0/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR Sbjct 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAARTTPEA MNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR Sbjct 61 AQWVQALAARTTPEATMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG Sbjct 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA Sbjct 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG Sbjct 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV Sbjct 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG Sbjct 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH Sbjct 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 Query 481 GCPPTLPFLAPGAP 494 GCPPTLPFLAPGAP Sbjct 481 GCPPTLPFLAPGAP 494 >gi|340625293|ref|YP_004743745.1| putative cobyric acid synthase COBQ1 [Mycobacterium canettii CIPT 140010059] gi|340003483|emb|CCC42603.1| putative cobyric acid synthase COBQ1 [Mycobacterium canettii CIPT 140010059] Length=494 Score = 953 bits (2464), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/494 (99%), Positives = 487/494 (99%), Gaps = 0/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDG GVEIGR Sbjct 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGAGVEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAA+ PE AMNPVLLKP DHRSHVVLMGKPWGEVASSSW AGRRALAEAACR Sbjct 61 AQWVQALAAKAVPEPAMNPVLLKPVGDHRSHVVLMGKPWGEVASSSWRAGRRALAEAACR 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG Sbjct 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALLAAEDQAL+AGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA Sbjct 181 TVALLAAEDQALIAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG Sbjct 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV Sbjct 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG Sbjct 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH Sbjct 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 Query 481 GCPPTLPFLAPGAP 494 GCPPTLPFLAPGAP Sbjct 481 GCPPTLPFLAPGAP 494 >gi|308370352|ref|ZP_07421199.2| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis SUMu003] gi|308372843|ref|ZP_07430103.2| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis SUMu005] gi|308373921|ref|ZP_07434145.2| cobyric acid synthase cobQ1 [Mycobacterium tuberculosis SUMu006] 7 more sequence titles Length=477 Score = 939 bits (2428), Expect = 0.0, Method: Compositional matrix adjust. Identities = 476/477 (99%), Positives = 477/477 (100%), Gaps = 0/477 (0%) Query 18 VTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQWVQALAARTTPEAAM 77 +TAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQWVQALAARTTPEAAM Sbjct 1 MTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQWVQALAARTTPEAAM 60 Query 78 NPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFDALAARYDVVVAEGA 137 NPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFDALAARYDVVVAEGA Sbjct 61 NPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFDALAARYDVVVAEGA 120 Query 138 GSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAGFV 197 GSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAGFV Sbjct 121 GSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAGFV 180 Query 198 VNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARRVA 257 VNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARRVA Sbjct 181 VNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARRVA 240 Query 258 VVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLD 317 VVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLD Sbjct 241 VVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLD 300 Query 318 RALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKV 377 RALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKV Sbjct 301 RALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKV 360 Query 378 LRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFL 437 LRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFL Sbjct 361 LRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFL 420 Query 438 RETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 RETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP Sbjct 421 RETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 477 >gi|118619015|ref|YP_907347.1| cobyric acid synthase [Mycobacterium ulcerans Agy99] gi|187470812|sp|A0PU57.1|COBQ_MYCUA RecName: Full=Cobyric acid synthase gi|118571125|gb|ABL05876.1| cobyric acid synthase CobQ1 [Mycobacterium ulcerans Agy99] Length=491 Score = 832 bits (2148), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/494 (87%), Positives = 444/494 (90%), Gaps = 3/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR Sbjct 1 MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAA TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W GR+ LA+ A R Sbjct 61 AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLADTAHR 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHA LPTIVVGDIDRGGVFAAF G Sbjct 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAELPTIVVGDIDRGGVFAAFFG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T+ALL+ EDQALVAGFVVNKFRGD DLLAPGLRDLERVTGR+V+GTLPWH DLWLDSEDA Sbjct 181 TIALLSVEDQALVAGFVVNKFRGDLDLLAPGLRDLERVTGRQVFGTLPWHADLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDL GRRAA GA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG Sbjct 241 LDLTGRRAASAGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP V E Sbjct 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 +GLGLLDVET F KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG Sbjct 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHGSLEGDALREAFLRETLGL SG+ F AARERRLDLLGDLVERHLDVDALL LARH Sbjct 418 TMWHGSLEGDALREAFLRETLGLTESGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477 Query 481 GCPPTLPFLAPGAP 494 GC P LPFL PGAP Sbjct 478 GCAPALPFLPPGAP 491 >gi|183983813|ref|YP_001852104.1| cobyric acid synthase CobQ1 [Mycobacterium marinum M] gi|238690942|sp|B2HNJ6.1|COBQ_MYCMM RecName: Full=Cobyric acid synthase gi|183177139|gb|ACC42249.1| cobyric acid synthase CobQ1 [Mycobacterium marinum M] Length=491 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/494 (87%), Positives = 444/494 (90%), Gaps = 3/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M GLLVAGTTSDAGKS +TAGLCRA ARRGVRVAPFKAQNMSNNSMVC+GP G GVEIGR Sbjct 1 MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAA TPEAAMNPVLLKP SDHRSHVVLMG+ WGE+ASS+W GR+ LAE A R Sbjct 61 AQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHR 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD LAARYDVVVAEGAGSPAEINLRAGDYVNMGLA HA LPTIVVGDIDRGGVFAAF G Sbjct 121 AFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T+ALL+AEDQALVAGFVVNKFRGD DLLAPGLRDLE VTGR+V+GTLPWH DLWLDSEDA Sbjct 181 TIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDL GRRAA TGA RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPR L DADLIV+PG Sbjct 241 LDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLRAR LDRAL+ HVAAGKPLLGICGGFQMLGRVIRDP G+EGP V E Sbjct 301 TRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGP---VAEA 357 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 +GLGLLDVET F KVLRLPRG+GLGV ASGYEIHHGRIT GD A++FLGGARDG VFG Sbjct 358 DGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFG 417 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHGSLEGDALREAFLRETLGL SG+ F AARERRLDLLGDLVERHLDVDALL LARH Sbjct 418 TMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARH 477 Query 481 GCPPTLPFLAPGAP 494 GC P LPFL PGAP Sbjct 478 GCAPALPFLPPGAP 491 >gi|145220964|ref|YP_001131642.1| cobyric acid synthase [Mycobacterium gilvum PYR-GCK] gi|187470807|sp|A4T0R6.1|COBQ_MYCGI RecName: Full=Cobyric acid synthase gi|145213450|gb|ABP42854.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Mycobacterium gilvum PYR-GCK] Length=491 Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/494 (81%), Positives = 432/494 (88%), Gaps = 3/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+GLLVAGTTSDAGK+AVT GLCRALARRGV+VAP+KAQNMSNNSMVC DG G EIGR Sbjct 1 MTGLLVAGTTSDAGKTAVTTGLCRALARRGVKVAPYKAQNMSNNSMVCTSVDGAGAEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAAR TPE AMNPVLLKP SD RSHVVLMG+PWG+V+SS W GRRALA AA Sbjct 61 AQWVQALAARATPEPAMNPVLLKPGSDRRSHVVLMGRPWGQVSSSDWLEGRRALATAAHE 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD LA+RY+VVVAEGAGSP EINLRAGDYVN+GLARHAGLPT+VVGDIDRGGVFAAF G Sbjct 121 AFDELASRYEVVVAEGAGSPTEINLRAGDYVNLGLARHAGLPTVVVGDIDRGGVFAAFFG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALL+ +DQAL+AGFVVNKFRGD DLLAPGLRDLER+TGRRVYGTLPWHPD+WLDSEDA Sbjct 181 TVALLSPQDQALIAGFVVNKFRGDVDLLAPGLRDLERLTGRRVYGTLPWHPDIWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 L+L GRR+A +GARRVAV+RLPRISNFTDVDALGLEPDLDVVFAS P +L DADL+VLPG Sbjct 241 LELAGRRSAQSGARRVAVIRLPRISNFTDVDALGLEPDLDVVFASHPGSLADADLVVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAWLR+R LD AL HVAAG+P+LGICGGFQMLGRVIRDP+G+EGP V V Sbjct 301 TRATIADLAWLRSRGLDSALRRHVAAGRPVLGICGGFQMLGRVIRDPHGVEGP---VAGV 357 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 +GLGLLDVET F P KVLRLP G G PA+GYEIHHGRITRGD +EFL GAR G VFG Sbjct 358 DGLGLLDVETTFGPDKVLRLPSGRWFGAPATGYEIHHGRITRGDGVDEFLDGARCGQVFG 417 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHG+LEGD LR FL+E LG+APSG F AARE RLDLLGDLVERHLDVDALL+LA+ Sbjct 418 TMWHGALEGDELRSRFLQEALGVAPSGVSFPAAREARLDLLGDLVERHLDVDALLDLAKT 477 Query 481 GCPPTLPFLAPGAP 494 G LPFL PGAP Sbjct 478 GPVAGLPFLPPGAP 491 >gi|315442065|ref|YP_004074944.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Mycobacterium sp. Spyr1] gi|315260368|gb|ADT97109.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Mycobacterium sp. Spyr1] Length=491 Score = 759 bits (1959), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/494 (80%), Positives = 424/494 (86%), Gaps = 3/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+GLLVAGTTSDAGK+AVT GLCRALARRGV+VAP+KAQNMSNNSMVC DG G EIGR Sbjct 1 MTGLLVAGTTSDAGKTAVTTGLCRALARRGVKVAPYKAQNMSNNSMVCTSVDGAGAEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAAR TPE AMNPVLLKP SD RSHVVLMG+PWG+V+SS W GRRALA AA Sbjct 61 AQWVQALAARATPEPAMNPVLLKPGSDRRSHVVLMGRPWGQVSSSDWLEGRRALATAAHA 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD LAARYDVVVAEGAGSP EINLRAGDYVN+GLARHAGLPT+VVGDIDRGGVFAAF G Sbjct 121 AFDDLAARYDVVVAEGAGSPTEINLRAGDYVNLGLARHAGLPTVVVGDIDRGGVFAAFFG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALL+ DQAL+AGFVVNKFRGD LL PGLRDLER+TGRRVYGT+PWHPDLWLDSEDA Sbjct 181 TVALLSPPDQALIAGFVVNKFRGDVALLEPGLRDLERLTGRRVYGTVPWHPDLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDLQGRR+A +GARRVAV+RLPRISNFTDVDALGLEP+LDVVFAS P L DADL+VLPG Sbjct 241 LDLQGRRSAQSGARRVAVIRLPRISNFTDVDALGLEPELDVVFASHPGGLADADLLVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRATIADLAW+R+R LD A+L H AAGKP+LGICGGFQMLG VIRDP+G+E G TEV Sbjct 301 TRATIADLAWMRSRGLDSAVLRHAAAGKPVLGICGGFQMLGTVIRDPHGVE---GATTEV 357 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 +GLGLLDVET F P K LRLP G+ LG PA+GYEIHHGRITRGD +EFL GAR G VFG Sbjct 358 DGLGLLDVETTFGPDKALRLPSGQWLGAPATGYEIHHGRITRGDGVDEFLAGARRGQVFG 417 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHG+LEGD LR FL E L LA SG F ARE RL+LLGDL ERHLDVDALL LAR Sbjct 418 TMWHGALEGDELRSRFLGEALNLAHSGVSFADAREARLELLGDLAERHLDVDALLELART 477 Query 481 GCPPTLPFLAPGAP 494 G P LPFL PGAP Sbjct 478 GPAPGLPFLPPGAP 491 >gi|120401402|ref|YP_951231.1| cobyric acid synthase [Mycobacterium vanbaalenii PYR-1] gi|187470813|sp|A1T225.1|COBQ_MYCVP RecName: Full=Cobyric acid synthase gi|119954220|gb|ABM11225.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Mycobacterium vanbaalenii PYR-1] Length=490 Score = 737 bits (1902), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/494 (79%), Positives = 422/494 (86%), Gaps = 4/494 (0%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+GLL+AGTTSDAGK+AVT GLCRALARRG++VAP+KAQNMSNNSMVC G DG GVEIGR Sbjct 1 MTGLLIAGTTSDAGKTAVTTGLCRALARRGLKVAPYKAQNMSNNSMVCAGDDG-GVEIGR 59 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAAR TPEAAMNPVLLKP SD RSHVVLMG+PWG V+SS W GRRALA AA Sbjct 60 AQWVQALAARATPEAAMNPVLLKPGSDRRSHVVLMGRPWGHVSSSDWLEGRRALAAAAHA 119 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 A+D LA RYDV+VAEGAGSP EINLRAGDYVN+GLARHAGLPT+VVGDIDRGGVFAAF G Sbjct 120 AYDDLAGRYDVIVAEGAGSPTEINLRAGDYVNLGLARHAGLPTVVVGDIDRGGVFAAFFG 179 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALL+ EDQAL+AGFVVNKFRGD LLAPGLRDLER+TGRRVYGTLPWHPDLWLDSEDA Sbjct 180 TVALLSPEDQALIAGFVVNKFRGDPALLAPGLRDLERLTGRRVYGTLPWHPDLWLDSEDA 239 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 L+LQGRR+A GARRVAVVRLPRISNFTDVDA GLEPDLDVVFAS P AL DADL+VLPG Sbjct 240 LELQGRRSARPGARRVAVVRLPRISNFTDVDAFGLEPDLDVVFASHPSALADADLVVLPG 299 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TR+TIADLAWLR+R LDRA+L H AAG+P+LGICGGFQMLGRVIRDP+G+E G +E Sbjct 300 TRSTIADLAWLRSRGLDRAVLAHAAAGRPVLGICGGFQMLGRVIRDPHGVE---GGTSEA 356 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 +GLGLLD+ET F K LRLP G+ ASGYEIHHGRIT G +EF GG R GPVFG Sbjct 357 DGLGLLDIETDFVADKALRLPEGQWEATSASGYEIHHGRITPGPGGDEFPGGVRCGPVFG 416 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TMWHG+ EGDALR FL ETLG+ SG+ F ARE R+DLLGDLVE HLDVDALL LA H Sbjct 417 TMWHGAFEGDALRARFLTETLGVPASGASFPKAREDRIDLLGDLVEEHLDVDALLRLAEH 476 Query 481 GCPPTLPFLAPGAP 494 P LPFL PG+P Sbjct 477 APPQGLPFLPPGSP 490 >gi|326333066|ref|ZP_08199317.1| cobyric acid synthase CobQ [Nocardioidaceae bacterium Broad-1] gi|325949140|gb|EGD41229.1| cobyric acid synthase CobQ [Nocardioidaceae bacterium Broad-1] Length=528 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/475 (78%), Positives = 399/475 (84%), Gaps = 3/475 (0%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQW 63 +LVAGTTSDAGKS VT GLCRA ARRGV+VAP+KAQNMSNNSMVC PDGT EIGRAQW Sbjct 1 MLVAGTTSDAGKSVVTTGLCRAFARRGVKVAPYKAQNMSNNSMVCEAPDGTTAEIGRAQW 60 Query 64 VQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFD 123 VQALAAR TPE AMNPVLLKP SD RSHVVLMG P GEV+S W AGRR LA AA A+D Sbjct 61 VQALAARVTPEPAMNPVLLKPGSDRRSHVVLMGHPAGEVSSHDWEAGRRHLATAAHAAYD 120 Query 124 ALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVA 183 LA+R++V+VAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAA GT+A Sbjct 121 DLASRFEVIVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAMYGTLA 180 Query 184 LLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDL 243 LL EDQAL++GFV+NKFRGD+ LL PGL LE +TGRRV+G LPW P LWLDSEDALDL Sbjct 181 LLDPEDQALISGFVINKFRGDAGLLKPGLDSLESLTGRRVFGVLPWEPSLWLDSEDALDL 240 Query 244 QGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRA 303 +GRRAA R+VAVVRLPRISNFTDVDALGLEPDLDVVFAS P + DADL+VLPGTR+ Sbjct 241 EGRRAAAGATRKVAVVRLPRISNFTDVDALGLEPDLDVVFASSPADVADADLVVLPGTRS 300 Query 304 TIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGL 363 TI+DLAWLR+R LD AL+ HV G+PLLGICGGFQMLG VI DP G+E G V EVEGL Sbjct 301 TISDLAWLRSRGLDVALVEHVRRGRPLLGICGGFQMLGGVIADPDGVE---GSVAEVEGL 357 Query 364 GLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMW 423 GLLDV T F+P K LRLP G LGV ASGYEIHHGRITRGD EFLGGAR G VFGTMW Sbjct 358 GLLDVRTDFAPAKNLRLPTGSALGVEASGYEIHHGRITRGDGVTEFLGGARAGNVFGTMW 417 Query 424 HGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLA 478 HGSLEGDALR AFL+ TLG PS F AARERRLDL+GDLVE HLDVDALL+LA Sbjct 418 HGSLEGDALRGAFLQATLGREPSSVSFPAARERRLDLIGDLVEEHLDVDALLDLA 472 >gi|333991818|ref|YP_004524432.1| cobyric acid synthase CobQ1 [Mycobacterium sp. JDM601] gi|333487786|gb|AEF37178.1| cobyric acid synthase CobQ1 [Mycobacterium sp. JDM601] Length=483 Score = 701 bits (1808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/494 (76%), Positives = 412/494 (84%), Gaps = 11/494 (2%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+GLL+AGTTSDAGK+ V GLCRALARRGVRVAP+KAQNMSNNSMVC G DGT EIGR Sbjct 1 MAGLLIAGTTSDAGKTVVATGLCRALARRGVRVAPYKAQNMSNNSMVCTGADGTATEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAAR PE AMNPVLLKP SD RSHVVLMG+PWGEV+SS W GRRALA+AA Sbjct 61 AQWVQALAARAVPEPAMNPVLLKPGSDQRSHVVLMGRPWGEVSSSDWREGRRALADAAHA 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 A+D LAARYDV++AEGAGSPAEINLR D+VNMGLARHA LPT+VVGDIDRGGVFA F G Sbjct 121 AYDDLAARYDVIIAEGAGSPAEINLRDSDFVNMGLARHADLPTVVVGDIDRGGVFAGFFG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALL A+DQAL+AGF+VNKFRGD+ LL PGLR+LER TGRRV+GTLPWHP+LWLDSEDA Sbjct 181 TVALLDAQDQALIAGFIVNKFRGDAGLLEPGLRELERRTGRRVFGTLPWHPELWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDL GRR+A TGARRVAV+RLPRISNFTD+DALGLEPDLDVVFASDPR + DADL+VLPG Sbjct 241 LDLDGRRSAKTGARRVAVIRLPRISNFTDLDALGLEPDLDVVFASDPRGVSDADLVVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRAT++DL WLR+R LD A++ H AAGKP+LGICGGFQMLGR IRDP GIEG GQV Sbjct 301 TRATVSDLGWLRSRGLDAAIVAHAAAGKPVLGICGGFQMLGRSIRDPEGIEGAPGQVA-- 358 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 GLGLLDVET F KVLRL G GYEIHHGRI+RG+ ++FLGG R G VFG Sbjct 359 -GLGLLDVETCFGAAKVLRLSDG--------GYEIHHGRISRGERVQDFLGGVRAGRVFG 409 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TM HGS E DALR FL E+LG+ PSG F ARE RLDLL DLVE+HLDVDALL L R Sbjct 410 TMRHGSFENDALRAEFLAESLGMEPSGVSFPGAREHRLDLLADLVEQHLDVDALLALTRG 469 Query 481 GCPPTLPFLAPGAP 494 G PP LPFLA GAP Sbjct 470 GPPPGLPFLAAGAP 483 >gi|298523723|ref|ZP_07011132.1| cobyric acid synthase [Mycobacterium tuberculosis 94_M4241A] gi|298493517|gb|EFI28811.1| cobyric acid synthase [Mycobacterium tuberculosis 94_M4241A] Length=387 Score = 701 bits (1808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/359 (100%), Positives = 359/359 (100%), Gaps = 0/359 (0%) Query 136 GAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAG 195 GAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAG Sbjct 29 GAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAG 88 Query 196 FVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARR 255 FVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARR Sbjct 89 FVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARR 148 Query 256 VAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARD 315 VAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARD Sbjct 149 VAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARD 208 Query 316 LDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPH 375 LDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPH Sbjct 209 LDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPH 268 Query 376 KVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREA 435 KVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREA Sbjct 269 KVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREA 328 Query 436 FLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 FLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP Sbjct 329 FLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 387 >gi|297560574|ref|YP_003679548.1| cobyric acid synthase CobQ [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296845022|gb|ADH67042.1| cobyric acid synthase CobQ [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=527 Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/483 (75%), Positives = 385/483 (80%), Gaps = 2/483 (0%) Query 7 AGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQWVQA 66 AGTTSDAGKS VT LCRA ARRG RVAP+KAQNMSNNSMVC GPDG EIGRAQWVQA Sbjct 27 AGTTSDAGKSVVTTALCRAFARRGARVAPYKAQNMSNNSMVCHGPDGRPAEIGRAQWVQA 86 Query 67 LAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFDALA 126 LAAR PE AMNPVLLKP +D RSH VL+G P G+V+S+ W AGRR LAEAA A+D LA Sbjct 87 LAARAVPEPAMNPVLLKPGTDRRSHAVLLGHPAGDVSSADWEAGRRHLAEAAHAAYDDLA 146 Query 127 ARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVALLA 186 +R+DVVVAEGAGSPAEINLRAGDYVNMGLARHAGLP +VVGDIDRGGVFAA GTV LL Sbjct 147 SRHDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPVVVVGDIDRGGVFAAMYGTVGLLE 206 Query 187 AEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDLQGR 246 DQ LVAGFVVNKFRGD LL PGL DLER+TGRRVYGTLPW P LWLDSEDALDL+GR Sbjct 207 PADQELVAGFVVNKFRGDPGLLRPGLEDLERLTGRRVYGTLPWDPGLWLDSEDALDLEGR 266 Query 247 RAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRATIA 306 R G RVAVVRLPRISNFTDVDALGLEP LDVVFAS PR + DADL+VLPGTR+T+A Sbjct 267 RTRGGAGLRVAVVRLPRISNFTDVDALGLEPGLDVVFASGPRDVADADLVVLPGTRSTLA 326 Query 307 DLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLL 366 DLAWLR+R LDRA++ H G+PLLGICGGFQMLGR + D G+E G +GLGLL Sbjct 327 DLAWLRSRGLDRAIVEHARRGRPLLGICGGFQMLGRTVTDADGVEAEPG--ARADGLGLL 384 Query 367 DVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGS 426 D T F+ K LRLP GE LG PA GYEIHHGR+T G AE F GGAR G VFGTMWHGS Sbjct 385 DARTDFTADKTLRLPSGEALGAPAHGYEIHHGRVTVGGGAEGFPGGARAGNVFGTMWHGS 444 Query 427 LEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTL 486 LEGDA R AFL E LG APSG F AARERRLDLL DL E HLDVDALL LAR G P L Sbjct 445 LEGDAFRAAFLAEALGCAPSGVRFAAARERRLDLLADLAEEHLDVDALLALAREGAPAGL 504 Query 487 PFL 489 P L Sbjct 505 PVL 507 >gi|119716735|ref|YP_923700.1| cobyric acid synthase [Nocardioides sp. JS614] gi|119537396|gb|ABL82013.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Nocardioides sp. JS614] Length=495 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/499 (71%), Positives = 390/499 (79%), Gaps = 12/499 (2%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSG+LVAGT+SDAGKS VT GLCR+LAR GV VAPFKAQNMSNNSMVC G EIGR Sbjct 1 MSGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVC----ADGAEIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQA+AA PEAAMNPVLLKP SD RSHVV+MG+P G + + + GR LA AA Sbjct 57 AQWVQAVAANAEPEAAMNPVLLKPGSDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYA 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD LA+RYDVVVAEGAGSPAEINLR+GD+VNMGLARHAGLPT+VVGDIDRGG+ AA G Sbjct 117 AFDDLASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTVVVGDIDRGGLLAAMFG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALL DQ L+AGFVVNKFRGD DLL PGL ++ R+TGR VYG LPWHPDLW+DSED Sbjct 177 TVALLEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDT 236 Query 241 LDLQGRRAA-GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLP 299 L + GR+A G A +VAVVRLPRISN TDVDALG+EP LDVVFA+DPRAL DADL+VLP Sbjct 237 LAVAGRQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLP 296 Query 300 GTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTE 359 GTRATIADLAWLR R LDRA+ H AAG+P+LGICGGFQMLGR + DP G+EG G E Sbjct 297 GTRATIADLAWLRERGLDRAVHAHAAAGRPVLGICGGFQMLGRSVSDPGGVEGQPG--AE 354 Query 360 VEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVF 419 VEGL LLDV T FS KVLRL RG LG +GYEIHHGR+TRG AEEFLGGAR+G V Sbjct 355 VEGLALLDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAGAEEFLGGAREGHVL 414 Query 420 GTMWHGSLEGDALREAFLRETLGLA-----PSGSCFLAARERRLDLLGDLVERHLDVDAL 474 GTMWHGSLEGDA R AFL E L PSG F AARE R++LL DLVE HLDV A+ Sbjct 415 GTMWHGSLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAI 474 Query 475 LNLARHGCPPTLPFLAPGA 493 LA G P LP L PGA Sbjct 475 AALASEGVPDGLPVLPPGA 493 >gi|119717104|ref|YP_924069.1| cobyric acid synthase [Nocardioides sp. JS614] gi|119537765|gb|ABL82382.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Nocardioides sp. JS614] Length=476 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/492 (73%), Positives = 385/492 (79%), Gaps = 19/492 (3%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLLVAGTTSDAGKS VT GLCRA ARRGVRVAP+KAQNMSNNSMVC GPD EIGR Sbjct 1 MSGLLVAGTTSDAGKSVVTTGLCRAFARRGVRVAPYKAQNMSNNSMVCAGPDERLAEIGR 60 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQALAAR TPE AMNPVLLKP SD RSHVVL+G+P GEV+S+SW GRR LAEAA Sbjct 61 AQWVQALAARATPEPAMNPVLLKPGSDRRSHVVLLGRPAGEVSSASWEEGRRHLAEAAHE 120 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD LA+RYDV+VAEGAGSPAEINLRAGDYVNMGLARHA LPT+VVGDIDRGGVFAA G Sbjct 121 AFDDLASRYDVIVAEGAGSPAEINLRAGDYVNMGLARHAALPTVVVGDIDRGGVFAALHG 180 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALLA +DQALVAGFV+NKFRGD LL+PGL L TGR YG LPW P LWLDSEDA Sbjct 181 TVALLAPDDQALVAGFVMNKFRGDLSLLSPGLEMLRLATGRPTYGVLPWDPSLWLDSEDA 240 Query 241 LDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPG 300 LDL GRR+AG+GA+RVAVVRLPRISNFTD+DALGLEPDLDVVFAS R L DADL+VLPG Sbjct 241 LDLDGRRSAGSGAKRVAVVRLPRISNFTDLDALGLEPDLDVVFASSARDLADADLVVLPG 300 Query 301 TRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEV 360 TRAT+ADLAW+RAR LD A++ H AG+ +LGICGG QMLGR I DP GIEG G V V Sbjct 301 TRATVADLAWMRARGLDGAIIAHADAGRAVLGICGGCQMLGRTITDPAGIEGDPGTV--V 358 Query 361 EGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFG 420 GLGLL T F KVLR+ PA GYEIHHGRI G DG V G Sbjct 359 AGLGLLPHTTTFGADKVLRVHE------PA-GYEIHHGRIA---------GRTEDGLVSG 402 Query 421 TMWHGSLEGDALREAFLRETLGLAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLARH 480 TM HGSLE DA R A+L+ LG+ S + F AAR+ R+DLLGDLVE+HLDVDALL LA Sbjct 403 TMVHGSLEDDAHRAAYLQRVLGVT-SRASFPAARDARIDLLGDLVEQHLDVDALLALAVS 461 Query 481 GCPPTLPFLAPG 492 G P LP L PG Sbjct 462 GAPAGLPVLPPG 473 >gi|257055791|ref|YP_003133623.1| cobyric acid synthase [Saccharomonospora viridis DSM 43017] gi|256585663|gb|ACU96796.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Saccharomonospora viridis DSM 43017] Length=498 Score = 622 bits (1604), Expect = 4e-176, Method: Compositional matrix adjust. Identities = 341/495 (69%), Positives = 381/495 (77%), Gaps = 12/495 (2%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQW 63 LLVAGTTSDAGK+ V GLCRA ARRG++VAPFKAQNMSNNSMVC G EIGRAQW Sbjct 11 LLVAGTTSDAGKTLVATGLCRAFARRGLKVAPFKAQNMSNNSMVC----ADGAEIGRAQW 66 Query 64 VQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFD 123 VQALAA PEAAMNPVLLKP D RSHVV++G+P GE+ S+ + GR LA+AA A+ Sbjct 67 VQALAAGVEPEAAMNPVLLKPGGDRRSHVVVLGRPAGELGSAEFPEGRAHLADAAYAAYR 126 Query 124 ALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVA 183 L++R+D+VV EGAGSPAEINLRAGDYVNMGLARH +PT++VGDIDRGGVFAAF GTVA Sbjct 127 DLSSRFDLVVCEGAGSPAEINLRAGDYVNMGLARHDDIPTVLVGDIDRGGVFAAFYGTVA 186 Query 184 LLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDL 243 LL DQAL+AGFVVNKFRGD LLAPGLR LE +TGRRVYGT+PW PD+WLDSED L L Sbjct 187 LLEPADQALIAGFVVNKFRGDDTLLAPGLRRLEELTGRRVYGTVPWSPDVWLDSEDTLGL 246 Query 244 QGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGTRA 303 GR A GA RV V+RLPRISN TD+DALGLEP ++VVF +DP L DADL+VLPGTRA Sbjct 247 AGRSPAEEGALRVVVIRLPRISNVTDLDALGLEPGVEVVFTADPYDLADADLVVLPGTRA 306 Query 304 TIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVEGL 363 T+ADLAWLR+R LDRA++ H AG+ +LGICGGFQMLGR + DP G+E G V GL Sbjct 307 TVADLAWLRSRGLDRAVVRHAEAGRAVLGICGGFQMLGRHVHDPEGVEASG--PVSVPGL 364 Query 364 GLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVFGTMW 423 GLL VET FSP K LR RG GV A GYEIHHGRITR EEFLGGAR G V GTMW Sbjct 365 GLLPVETTFSPDKTLRRSRGTAFGVEAFGYEIHHGRITRDVGVEEFLGGARVGRVLGTMW 424 Query 424 HGSLEGDALREAFLR---ETLG--LAPSGSCFLAARERRLDLLGDLVERHLDVDALLNLA 478 HGSLE DALR A L E G A SG F +RE RLDLLGDLVERHLDVDALL LA Sbjct 425 HGSLESDALRTAVLNFAAEARGRSFAASGVDFARSREARLDLLGDLVERHLDVDALLALA 484 Query 479 RHGCPPTLPFLAPGA 493 +HG P +P + P A Sbjct 485 QHG-PGHVPTIGPHA 498 >gi|319948916|ref|ZP_08023025.1| cobyric acid synthase [Dietzia cinnamea P4] gi|319437424|gb|EFV92435.1| cobyric acid synthase [Dietzia cinnamea P4] Length=519 Score = 592 bits (1525), Expect = 7e-167, Method: Compositional matrix adjust. Identities = 342/503 (68%), Positives = 375/503 (75%), Gaps = 15/503 (2%) Query 2 SGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRA 61 + LLVAGTTSDAGKS VT LCRA ARRG+RVAPFKAQNMSNNS V GPD T EIGRA Sbjct 19 ASLLVAGTTSDAGKSIVTTALCRAFARRGLRVAPFKAQNMSNNSTVVGGPDAT-AEIGRA 77 Query 62 QWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRA 121 QW+QALAAR PE AMNPVLLKP D RSHVV+MG+P G V+S + GR LAEAA A Sbjct 78 QWIQALAARADPEPAMNPVLLKPGGDRRSHVVVMGQPAGSVSSRDFVDGRAHLAEAAFAA 137 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 +D LA+RYD+V+ EGAGSPAEINLR+ DYVNMGLARHA +P +VVGDIDRGGVFAA GT Sbjct 138 YDDLASRYDLVICEGAGSPAEINLRSSDYVNMGLARHADMPVVVVGDIDRGGVFAALFGT 197 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALL DQ LVAGFVVNKFRGD LL PGLR L +TGR V+G LPWHPDLWLDSEDAL Sbjct 198 VALLEPTDQRLVAGFVVNKFRGDPTLLEPGLRQLTALTGRPVHGVLPWHPDLWLDSEDAL 257 Query 242 DLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLPGT 301 + R A + A RVAV+RLPRISNFTDVDALGLE D++V + ++PR L ADL+V+PGT Sbjct 258 AVSPRAADASAALRVAVIRLPRISNFTDVDALGLEADVEVAYVTEPRDLAGADLVVVPGT 317 Query 302 RATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTEVE 361 RAT+ DL WLRAR LDRA+ HV G +LGICGGFQMLGR I DP GIEG G V Sbjct 318 RATLDDLTWLRARGLDRAVTTHVERGGAVLGICGGFQMLGREIADPDGIEGEPG--ARVA 375 Query 362 GLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRIT------RGDTAEEFLGGARD 415 GLGLLDV T F KVLRLP G LG P SGYEIHHGR++ GD E F GGAR Sbjct 376 GLGLLDVTTRFGVEKVLRLPTGTALGQPVSGYEIHHGRVSVGGGGETGDDDEVFPGGARR 435 Query 416 GPVFGTMWHGSLEGDALREAFLRETLGLA-----PSGSCFLAARERRLDLLGDLVERHLD 470 G VFGTMWHGSLE D R AFL E + PSG F AARERRLDLLGDL E HLD Sbjct 436 GRVFGTMWHGSLESDGFRGAFLGEVAAGSGRTREPSGVSFAAARERRLDLLGDLAEEHLD 495 Query 471 VDALLNLARHGCPPTLPFLAPGA 493 +DALL LAR G P LP L PGA Sbjct 496 LDALLALARDGA-PELPLLPPGA 517 >gi|311744336|ref|ZP_07718138.1| cobyric acid synthase CobQ [Aeromicrobium marinum DSM 15272] gi|311312302|gb|EFQ82217.1| cobyric acid synthase CobQ [Aeromicrobium marinum DSM 15272] Length=487 Score = 549 bits (1415), Expect = 3e-154, Method: Compositional matrix adjust. Identities = 328/498 (66%), Positives = 363/498 (73%), Gaps = 20/498 (4%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+GLLVAGTTSDAGKS VT LCRA ARRGVRVAPFKAQNMSN+SMV G EIGR Sbjct 1 MTGLLVAGTTSDAGKSVVTTALCRAFARRGVRVAPFKAQNMSNDSMVT----ADGAEIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQA AAR PEAAMNPVLLKP D RSHVV+MG+P G ++S+ + GR LA AA Sbjct 57 AQWVQARAARAEPEAAMNPVLLKPGGDRRSHVVVMGRPAGSLSSADFLGGRGRLATAAFA 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AFD L RYDVVVAEGAGSP EINLR D+VNMGLARH LP +VVGDIDRGGVFAA G Sbjct 117 AFDDLRGRYDVVVAEGAGSPTEINLREHDFVNMGLARHGDLPVVVVGDIDRGGVFAALHG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T+ALL DQ LV+ FV+NKFRGD LL P L + +TGR G LPW LWLDSEDA Sbjct 177 TLALLDGADQDLVSAFVLNKFRGDPSLLGPALDRITALTGRPFAGVLPWDSGLWLDSEDA 236 Query 241 LDLQGRRAAGTGAR-RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLP 299 LDL GRR+ GA RVAVVRLPRISNFTDVDALG+EP +DVVFAS+PR LD ADL+VLP Sbjct 237 LDLDGRRSGDAGAALRVAVVRLPRISNFTDVDALGIEPGVDVVFASEPRHLDPADLVVLP 296 Query 300 GTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTE 359 GTRATI DLAWLR+R LDRA++ H AAG+ +LGICGG QMLGR I DP+G+EG G Sbjct 297 GTRATIDDLAWLRSRGLDRAIVRHAAAGRSVLGICGGMQMLGRSIADPHGVEGEPG--AR 354 Query 360 VEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVF 419 VEGLGLLDV T F+ KVLRL GYEIHHGR+TRG E+ GGAR G V Sbjct 355 VEGLGLLDVTTEFTVDKVLRL--------HGPGYEIHHGRVTRGPGTEDHPGGARAGAVA 406 Query 420 GTMWHGSLEGDALREAFLRET-----LGLAPSGSCFLAARERRLDLLGDLVERHLDVDAL 474 GTMWHG LE D R L E + LAP+ + F RE RLDLL DL E HLDVDAL Sbjct 407 GTMWHGCLEDDTARRDLLTEAARAAGIDLAPATASFEQHREARLDLLADLAEEHLDVDAL 466 Query 475 LNLARHGCPPTLPFLAPG 492 L+LA G P LP +APG Sbjct 467 LDLATTGAPAGLPRIAPG 484 >gi|284031614|ref|YP_003381545.1| cobyric acid synthase CobQ [Kribbella flavida DSM 17836] gi|283810907|gb|ADB32746.1| cobyric acid synthase CobQ [Kribbella flavida DSM 17836] Length=486 Score = 536 bits (1380), Expect = 4e-150, Method: Compositional matrix adjust. Identities = 305/500 (61%), Positives = 354/500 (71%), Gaps = 21/500 (4%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+ LL+AGTTSDAGK+ V GLCR LAR+GVRVAPFKAQNMSNNSMVC G EIGR Sbjct 1 MNSLLIAGTTSDAGKTTVVTGLCRWLARQGVRVAPFKAQNMSNNSMVC----ADGAEIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQW+QA+AA PEAAMNPVLLKP SD RSHVVLMG+PWGE+ + + R LA+AA Sbjct 57 AQWIQAVAAGAAPEAAMNPVLLKPGSDRRSHVVLMGEPWGELTARGFLTERAELAKAAFA 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 A+D LA+RYDVVV+EGAGSP EINLR DYVNMGLARHA P +VVGDIDRGGVFA+ G Sbjct 117 AYDDLASRYDVVVSEGAGSPTEINLRQSDYVNMGLARHAQAPVVVVGDIDRGGVFASMFG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 TVALL+ +DQ LV+GFVVNKFRGD LL PG+ L VTGR YG LPW PDLWLDSEDA Sbjct 177 TVALLSTDDQRLVSGFVVNKFRGDVSLLRPGIDMLTGVTGRPTYGVLPWLPDLWLDSEDA 236 Query 241 LDLQGRRAAGTG-ARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLP 299 LDL RR + G +AVVR PRISNFTD+DAL +EP V F + P + DADL+VLP Sbjct 237 LDLPARRTSTDGDVLTIAVVRFPRISNFTDLDALAVEPTTSVFFTAGPAEVRDADLVVLP 296 Query 300 GTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTE 359 G+RAT ADLAWLR L A+ VAAG+P+LGICGG+QMLG +I DPYG+E GG+ T Sbjct 297 GSRATTADLAWLREHGLADAVQARVAAGRPVLGICGGYQMLGGMIDDPYGVES-GGRHT- 354 Query 360 VEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVF 419 GLGLL V T F+ KVL P + YEIHHG + + A++F GG R G V+ Sbjct 355 --GLGLLPVATEFAAAKVLARP-------ARTAYEIHHGVVAQTAEADDFPGGCRSGVVW 405 Query 420 GTMWHGSLEGDALREAFLRETLGL----APSGSC-FLAARERRLDLLGDLVERHLDVDAL 474 GT+WHG L+ DA R FL E L AP G+ F RERRLD L D ++ HLD AL Sbjct 406 GTIWHGLLDDDAARHRFLGEIAALTGKPAPDGTVSFAGLRERRLDRLADAIDEHLDTAAL 465 Query 475 LNLARHGCPPTLPFLAPGAP 494 + L G P L F+ PGAP Sbjct 466 MTLIEKGAPADLRFVPPGAP 485 >gi|300788873|ref|YP_003769164.1| adenosylcobyric acid synthase [Amycolatopsis mediterranei U32] gi|299798387|gb|ADJ48762.1| adenosylcobyric acid synthase [Amycolatopsis mediterranei U32] gi|340530497|gb|AEK45702.1| cobyric acid synthase [Amycolatopsis mediterranei S699] Length=493 Score = 528 bits (1359), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 305/502 (61%), Positives = 343/502 (69%), Gaps = 17/502 (3%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLLVAGTTSDAGKS VTAG+CR LARRGV+VAPFKAQNMSNNSMVC G EIGR Sbjct 1 MSGLLVAGTTSDAGKSLVTAGICRWLARRGVQVAPFKAQNMSNNSMVC----ADGAEIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQWVQA AA PEAAMNPVLLKP SD RSHVV +GKP+G + + + GR LAE A Sbjct 57 AQWVQARAAGVEPEAAMNPVLLKPGSDRRSHVVALGKPFGTLEAGEYATGRAGLAEIAFG 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AF+ L+AR+DVVV EGAGSPAEINLR GDYVNMGLAR GLP +VVGDIDRGGV AA G Sbjct 117 AFEDLSARFDVVVCEGAGSPAEINLRGGDYVNMGLARRFGLPVLVVGDIDRGGVLAAMFG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T+ALL+AEDQALVAG+VVNKFRGD LL PGL LE VTGR V G LPW +W+DSEDA Sbjct 177 TLALLSAEDQALVAGWVVNKFRGDVGLLRPGLDSLENVTGRPVLGVLPWLDRVWIDSEDA 236 Query 241 LDLQGRRAAGTGARR-VAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLP 299 L + G R G R VAVVR PR SN TDVDAL EP + V +DP + AD++VLP Sbjct 237 LAVAGWRRETPGGRLGVAVVRFPRTSNATDVDALAAEPGVTVTLTADPDVVAAADVVVLP 296 Query 300 GTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTE 359 G+RAT+ADLAWLR R LD A+ AAG+P+LGICGG+QML I D + E G E Sbjct 297 GSRATVADLAWLRERGLDTAVTARAAAGRPVLGICGGYQMLTESIVDEF--ESGAG---E 351 Query 360 VEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVF 419 V GLGLL F+ KVL P G G P YEIHHG + +AE FL G R G V+ Sbjct 352 VAGLGLLPGRVTFAAEKVLARPAGTWRGHPVDAYEIHHGSVIATTSAESFLDGRRAGAVW 411 Query 420 GTMWHGSLEGDALREAFLRETLGL-------APSGSCFLAARERRLDLLGDLVERHLDVD 472 GTMWHG+ E DA R A+L E AP F RE LD L D V+ HLD + Sbjct 412 GTMWHGAFENDAFRRAWLTEAAAQAGTGWTPAPDAPGFGDLREEMLDKLADAVDEHLDTE 471 Query 473 ALLNLARHGCPPTLPFLAPGAP 494 L L G PP LPF+ PGAP Sbjct 472 LLRTLLDRGAPPDLPFVPPGAP 493 >gi|72160713|ref|YP_288370.1| cobyric acid synthase [Thermobifida fusca YX] gi|71914445|gb|AAZ54347.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Thermobifida fusca YX] Length=501 Score = 509 bits (1312), Expect = 4e-142, Method: Compositional matrix adjust. Identities = 295/490 (61%), Positives = 341/490 (70%), Gaps = 11/490 (2%) Query 2 SGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRA 61 GLLVAGT+SDAGKS VT+ LCRALAR G++VAPFKAQNMSNNSMV GPDGTG EI RA Sbjct 5 QGLLVAGTSSDAGKSLVTSALCRALARHGIKVAPFKAQNMSNNSMVVPGPDGTGAEISRA 64 Query 62 QWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRA 121 QWVQALAAR PE AMNPVLLKP+SD SHVVL G+P+G +A+ + R LAEAA A Sbjct 65 QWVQALAARAEPETAMNPVLLKPSSDRGSHVVLRGRPFGRLAAGEFAGTRAVLAEAAYAA 124 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L +RYDVVV EGAG AEINLRA DY+NMGLAR A LP IV+GDI+RGGVFA+ G+ Sbjct 125 LAELRSRYDVVVCEGAGGVAEINLRAHDYINMGLARAADLPVIVIGDINRGGVFASLYGS 184 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 +ALL DQALVAGFV+NKFRGD LL P L+ LE +TGR V G LPW +LWL+SED+L Sbjct 185 LALLDPADQALVAGFVINKFRGDPSLLDPALKTLEDLTGRPVLGVLPWQQNLWLESEDSL 244 Query 242 DLQGRR--AAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLP 299 L R +AGT RVAVVRLPRI N TDVDALG+EP L V F + PR L AD++VLP Sbjct 245 ALTAREDGSAGTPVLRVAVVRLPRIGNTTDVDALGVEPGLRVDFVTSPRLLASADIVVLP 304 Query 300 GTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTE 359 TRA + DL WLR+R L A+ H G +LGI GGFQMLGR I D G+EGP G+ Sbjct 305 DTRAVLTDLEWLRSRGLADAIANHARHGGTVLGIGGGFQMLGRTIVDAEGVEGPAGRT-- 362 Query 360 VEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVF 419 V GL LLD+ET F+ ++ L G G+P GY+ H+ RI GD E F GG R+G VF Sbjct 363 VAGLSLLDLETVFTRNQTLNYSSGTWQGIPVGGYQSHYSRIQTGD-GEAFPGGLRNGSVF 421 Query 420 GTMWHGSLEGDALREAFLRETL------GLAPSGSCFLAARERRLDLLGDLVERHLDVDA 473 GTMWHGSLE DA R A+L G CF R+ LD LGDL E HLD+DA Sbjct 422 GTMWHGSLEHDAFRGAWLAAAAENAGYDGSEYGQVCFAEVRDAYLDRLGDLAEEHLDMDA 481 Query 474 LLNLARHGCP 483 +L L G P Sbjct 482 VLRLITEGAP 491 >gi|302529226|ref|ZP_07281568.1| cobyric acid synthase CobQ [Streptomyces sp. AA4] gi|302438121|gb|EFL09937.1| cobyric acid synthase CobQ [Streptomyces sp. AA4] Length=492 Score = 504 bits (1297), Expect = 2e-140, Method: Compositional matrix adjust. Identities = 291/505 (58%), Positives = 332/505 (66%), Gaps = 24/505 (4%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSGLL+AGTTSDAGKS VTAGLCR ARRGVRVAPFKAQNMSNNSMVC G EIGR Sbjct 1 MSGLLIAGTTSDAGKSLVTAGLCRWFARRGVRVAPFKAQNMSNNSMVC----ADGAEIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQW+QA AAR PEAAMNPVLLKP SD RSHV+ +GKP+G + + + GR LA+ A Sbjct 57 AQWLQARAARVEPEAAMNPVLLKPGSDRRSHVIALGKPYGTLEAGEYATGRAGLADIAFA 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 AF L R+D+VV EGAGSPAEINLR+GDYVN+GLAR LP +VVGDIDRGGV AA G Sbjct 117 AFAELRQRFDLVVCEGAGSPAEINLRSGDYVNLGLARRFSLPVLVVGDIDRGGVLAAMFG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T+ALL+ EDQALVAG++VNKFRGD LL PGL LE+VTGR V G LPW +W+DSEDA Sbjct 177 TLALLSPEDQALVAGWLVNKFRGDVGLLQPGLNSLEKVTGRPVLGVLPWLDRVWIDSEDA 236 Query 241 LDLQG-RRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVLP 299 L G R A RVAVVR PR SN TDVDAL EP + V +DP + ADL+VLP Sbjct 237 LAAAGWRHEAAQRGLRVAVVRFPRASNATDVDALAAEPGVTVSLTADPDTVAAADLVVLP 296 Query 300 GTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVTE 359 G+RAT+ DL WLR R L A+ AG P+LGICGG+QML I D +E G Sbjct 297 GSRATVDDLKWLRTRGLADAVTARAKAGLPVLGICGGYQMLAESIED--NVESEAGL--- 351 Query 360 VEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPVF 419 VEGLGLL F+ KVL P GE G YEIHHG D AE FL G R G V+ Sbjct 352 VEGLGLLPTRVKFAEEKVLGRPVGEWRGHRVEAYEIHHGSAGSAD-AESFLDGYRVGSVW 410 Query 420 GTMWHGSLEGDALREAFLR----------ETLGLAPSGSCFLAARERRLDLLGDLVERHL 469 GT WHG+LE D R A+L + + AP F RE LD L D ++ + Sbjct 411 GTTWHGALENDGFRRAWLAEAAAQAGIEWQAVEGAPG---FADLREDMLDRLADAIQSEV 467 Query 470 DVDALLNLARHGCPPTLPFLAPGAP 494 D LL LA G P LPF+ PGAP Sbjct 468 DTGMLLALAEAGAPGGLPFVPPGAP 492 >gi|238060673|ref|ZP_04605382.1| cobyric acid synthase cobQ [Micromonospora sp. ATCC 39149] gi|237882484|gb|EEP71312.1| cobyric acid synthase cobQ [Micromonospora sp. ATCC 39149] Length=514 Score = 499 bits (1285), Expect = 4e-139, Method: Compositional matrix adjust. Identities = 306/516 (60%), Positives = 342/516 (67%), Gaps = 30/516 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS +TAG+CR L RRGV+VAPFKAQNMSNNS V GPDG G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVLTAGICRWLRRRGVKVAPFKAQNMSNNSAVVVGPDGRGGEIGRAQ 63 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 +QA A + NPVLLKP SD S VVL+G+ V + ++ A R LAEAA + Sbjct 64 AMQAAACGVAADLRFNPVLLKPGSDRSSQVVLLGEAVDTVTAGNYHALRPRLAEAAFASL 123 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 L Y+VVV EGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFA+ GTV Sbjct 124 AELREAYEVVVCEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFASMFGTV 183 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL- 241 ALL DQALVAGFV+NKFRGD LL PGL L RVTGR YG LPWH DLWLD+ED+L Sbjct 184 ALLDPADQALVAGFVINKFRGDRGLLQPGLDMLTRVTGRPTYGVLPWHLDLWLDAEDSLA 243 Query 242 --DLQGRRAA--GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 + GR AA GT VAVVRLPRISN TDV+AL EP + V +P L AD++V Sbjct 244 YGRVLGRPAAPHGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADIVV 303 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPG+++T+ADLAWLR L A+ H AAGKPLLGICGGFQMLGR + DP +E G V Sbjct 304 LPGSKSTVADLAWLRRTGLADAVAAHAAAGKPLLGICGGFQMLGRAVHDP--VESRAGSV 361 Query 358 TEVEGLGLLDVETAFSPHKVLR---LPRGEGLGVPASGYEIHHGRITRGDTAEEFL---- 410 GLGLL VE F+ K +R GVP GYEIHHG ++ D A L Sbjct 362 A---GLGLLPVEVTFAARKTVRQAAGTAAADAGVPVRGYEIHHGYVSSADPALPPLLSYD 418 Query 411 ----GGARDGPVFGTMWHGSLEGDALREAFL--------RETLGLAPSGSCFLAARERRL 458 GA G V GT WHG+ E DA R FL R +AP S F AARER L Sbjct 419 DGTGEGAVLGAVCGTHWHGAFESDAFRRRFLTDAARLAGRTGFRVAPDTS-FAAARERSL 477 Query 459 DLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 DLLGDLVE HLD AL L G P LPF+ PGAP Sbjct 478 DLLGDLVEEHLDTAALWRLIECGPPAGLPFIPPGAP 513 >gi|330469709|ref|YP_004407452.1| cobyric acid synthase CobQ [Verrucosispora maris AB-18-032] gi|328812680|gb|AEB46852.1| cobyric acid synthase CobQ [Verrucosispora maris AB-18-032] Length=512 Score = 498 bits (1281), Expect = 1e-138, Method: Compositional matrix adjust. Identities = 294/513 (58%), Positives = 334/513 (66%), Gaps = 26/513 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS +TAG+CR L R GV+VAPFKAQNMSNNS V GPDG G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVLTAGICRWLHREGVKVAPFKAQNMSNNSAVVVGPDGRGGEIGRAQ 63 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 +QA A P+ NPVLLKP SD S VVL+G+ + + ++ + R LAE A A Sbjct 64 AMQAAACGIAPDLRFNPVLLKPGSDLSSQVVLLGEAVDTLTADTFTSLRPRLAETAYAAL 123 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 L + YDVVV EGAGSPAEINLR GDYVNMGLAR AGLPTIVVGDIDRGGVFAA GT+ Sbjct 124 SELRSAYDVVVCEGAGSPAEINLRDGDYVNMGLARQAGLPTIVVGDIDRGGVFAAMFGTL 183 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL- 241 ALL DQAL+AGFVVNKFRGD LL PGL L +VTGR YG LPW DLWLD+ED+L Sbjct 184 ALLDPADQALIAGFVVNKFRGDRGLLEPGLAMLSQVTGRPTYGVLPWAVDLWLDAEDSLA 243 Query 242 --DLQGRRAA--GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 + GR AA GT VAVVRLPR+SN TDV+AL EP + V +P L ADL+V Sbjct 244 YGRVLGRPAAPHGTEWLDVAVVRLPRVSNATDVEALATEPGVRVRLTVEPAELAAADLVV 303 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPG+++T+ADLAWLR L + HVAAG+PLLGICGGFQML R I DP +E G V Sbjct 304 LPGSKSTVADLAWLRETGLADVITAHVAAGRPLLGICGGFQMLARAIHDP--VESRRGSV 361 Query 358 TEVEGLGLLDVETAFSPHKVLRLPRGE-GLGVPASGYEIHHGRITRGDTAEEFL------ 410 + GLGLL +E F P K +R G +P GYEIHHG ++ D L Sbjct 362 S---GLGLLPIEITFDPRKTVRAATGTFSDDLPVGGYEIHHGYVSAADPTLTPLLRYLDG 418 Query 411 --GGARDGPVFGTMWHGSLEGDALREAFLRETLGLA-------PSGSCFLAARERRLDLL 461 GA G V GT WHG+ E D R FL LA + F AAR R LDLL Sbjct 419 GGEGAVHGVVHGTHWHGAFESDEFRRWFLTRVSRLAGRTGFRVAQDTSFAAARNRTLDLL 478 Query 462 GDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 GDLVE HLD AL L G P LPF+ PGAP Sbjct 479 GDLVEEHLDTAALRRLIESGPPIDLPFVPPGAP 511 >gi|256395157|ref|YP_003116721.1| cobyric acid synthase CobQ [Catenulispora acidiphila DSM 44928] gi|256361383|gb|ACU74880.1| cobyric acid synthase CobQ [Catenulispora acidiphila DSM 44928] Length=529 Score = 493 bits (1270), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 284/523 (55%), Positives = 343/523 (66%), Gaps = 38/523 (7%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRG------------- 50 LLVAGTTSDAGKS +TAG+CR LAR+GVRVAPFKAQNMSNNSMV Sbjct 11 LLVAGTTSDAGKSLITAGICRWLARQGVRVAPFKAQNMSNNSMVVGVAGAANAAHGATGA 70 Query 51 PDGTGVEIGRAQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAG 110 G G EIGRAQ +QA AA PE AMNPVLLKP SD S VVL+G+ + E +++S+ Sbjct 71 TPGVGAEIGRAQVMQAQAAGVEPEVAMNPVLLKPGSDRTSQVVLLGQVFAEASATSYQEL 130 Query 111 RRALAEAACRAFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDID 170 + L EA ++ L +R+DVV+ EGAGSP EINLR GD VNMGLA+ G+P +VVGDID Sbjct 131 KPRLREAVLASYQDLKSRFDVVICEGAGSPTEINLRDGDLVNMGLAQPLGMPVVVVGDID 190 Query 171 RGGVFAAFLGTVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWH 230 RGGVFAAF GTVALL A DQ LV+GF++NKFRGD LL PGLR +E TGR V+G +PW Sbjct 191 RGGVFAAFHGTVALLDAADQKLVSGFIINKFRGDPSLLTPGLRQIEDFTGRPVFGVVPWL 250 Query 231 PDLWLDSEDALDLQGRRAAGT------GAR-RVAVVRLPRISNFTDVDALGLEPDLDVVF 283 P + LD+EDAL ++ A GAR RVAVVR PR+SNFTDVDAL +EP +DV F Sbjct 251 PGIRLDAEDALPIEAYAAGARDGALDGGARLRVAVVRFPRVSNFTDVDALAIEPGVDVEF 310 Query 284 ASDPRALDDADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRV 343 + A++ ADL+VLPGT++T+ADLAWLR R L+ AL A G+P+LGICGG+QMLG V Sbjct 311 TASAAAVESADLVVLPGTKSTVADLAWLRERGLEPALAKRAAEGRPILGICGGYQMLGTV 370 Query 344 IRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRI--- 400 I D +E G V GLGLL V T F P K L P G GLG P GYEIH+G++ Sbjct 371 IEDE--VESRRGTVA---GLGLLPVRTVFDPVKTLTRPTGFGLGEPVGGYEIHNGQVRVE 425 Query 401 ----TRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFLRET-----LGLAPSGSC-F 450 D + L G +DG V+GT+WHG+LE D R A+L E L P F Sbjct 426 GGESLFTDASGAALEGCQDGAVWGTIWHGALESDGFRRAYLAEVARVCGLRFEPDPDVSF 485 Query 451 LAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGA 493 A RE++LD LGD VE ++D + L L G LP L PGA Sbjct 486 AAEREKQLDRLGDAVEEYVDTERLWRLIEDGPTAGLPLLPPGA 528 >gi|159039457|ref|YP_001538710.1| cobyric acid synthase CobQ [Salinispora arenicola CNS-205] gi|157918292|gb|ABV99719.1| cobyric acid synthase CobQ [Salinispora arenicola CNS-205] Length=575 Score = 491 bits (1264), Expect = 1e-136, Method: Compositional matrix adjust. Identities = 301/516 (59%), Positives = 342/516 (67%), Gaps = 32/516 (6%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS +TAG+CR L RRGVRVAPFKAQNMSNNS V GPDG G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVLTAGICRWLHRRGVRVAPFKAQNMSNNSAVVVGPDGRGGEIGRAQ 63 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 +QA A P+ NPVLLKP SD S VVL+G+ + + ++ R LA+ A A Sbjct 64 AMQAAACGLAPDLRFNPVLLKPGSDRTSQVVLLGEAVDTLTTGTFRQLRPRLADTAYAAL 123 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 L A +DVV+ EGAGSPAEINLRAGDYVNMGLARHAGLP IVVGDIDRGGVFA+ GTV Sbjct 124 ADLRATHDVVICEGAGSPAEINLRAGDYVNMGLARHAGLPAIVVGDIDRGGVFASMFGTV 183 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL- 241 ALL DQALVAGFV+NKFRGD LLAPGL L +VTGR YG LPW DLWLD+ED+L Sbjct 184 ALLEPADQALVAGFVINKFRGDPSLLAPGLDMLRQVTGRPTYGVLPWALDLWLDAEDSLA 243 Query 242 --DLQGRRAAGTGAR--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 + GR AA G+ VAVVRLPRISN TDV+AL EP + V +P L ADL+V Sbjct 244 YGRVLGRPAAPRGSDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADLVV 303 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPG+++T+ADL WLR L A+L H AAG+PLLG+CGGFQMLGR+I DP +E G Sbjct 304 LPGSKSTVADLDWLRQSGLADAVLAHAAAGRPLLGVCGGFQMLGRLIHDP--VESRRGS- 360 Query 358 TEVEGLGLLDVETAFSPHKVLRLPRGEGLG---VPASGYEIHHGRITRG--DTAEEFL-- 410 V GLGLL VE F P K +R R G+G P GYEIHHG ++ D A F Sbjct 361 --VPGLGLLPVEVTFDPCKTVR--RSAGIGWDAEPVGGYEIHHGYVSAAAPDLAPLFAYH 416 Query 411 ----GGARDGPVFGTMWHGSLEGDALREAFL--------RETLGLAPSGSCFLAARERRL 458 GA G V+GT WHG+ E D R FL R +AP S F ARER L Sbjct 417 DGTGEGAVAGSVYGTHWHGAFESDGFRRRFLARVARQAGRHGFQVAPDTS-FAGARERSL 475 Query 459 DLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 DLLGDLVE HLD L L G P LPF+ PGAP Sbjct 476 DLLGDLVEEHLDTAGLWRLIESGPSPGLPFIPPGAP 511 >gi|302869419|ref|YP_003838056.1| cobyric acid synthase CobQ [Micromonospora aurantiaca ATCC 27029] gi|302572278|gb|ADL48480.1| cobyric acid synthase CobQ [Micromonospora aurantiaca ATCC 27029] Length=514 Score = 490 bits (1262), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 297/497 (60%), Positives = 331/497 (67%), Gaps = 28/497 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS +TAG+CR L RRGVRVAPFKAQNMSNNS V GPDG G E+GRAQ Sbjct 4 GLLVAGTTSDAGKSVLTAGICRWLRRRGVRVAPFKAQNMSNNSAVVVGPDGRGGELGRAQ 63 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 +QA A + NPVLLKP SDH S VVL+G+ V + ++ R LA A A Sbjct 64 AMQAAACGLDADLRFNPVLLKPGSDHASQVVLLGEAVDTVTAGNYHEVRSRLASTAYAAL 123 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 L + YDVV+ EGAGSPAEINLR GDYVNMGLAR AGLPTIVVGDIDRGGVFA+ GTV Sbjct 124 AELRSEYDVVICEGAGSPAEINLRDGDYVNMGLARQAGLPTIVVGDIDRGGVFASMFGTV 183 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL- 241 ALL A DQAL+AGFVVNKFRGD LL PGL L RVTGR YG +PW DLWLD+ED+L Sbjct 184 ALLDAADQALLAGFVVNKFRGDRGLLQPGLDMLHRVTGRPTYGVVPWALDLWLDAEDSLA 243 Query 242 --DLQGRRAA--GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 + GR A GT VAVVRLPRISN TDV+AL EP + V +P L ADL+V Sbjct 244 YGRVLGRPPAPRGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADLVV 303 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPGT++T+ADLAWLR L A+ H AAG+PLLGICGGFQMLGR I D +E G Sbjct 304 LPGTKSTVADLAWLRETGLADAVRAHAAAGRPLLGICGGFQMLGRAIHD--AVESRRGT- 360 Query 358 TEVEGLGLLDVETAFSPHKVLRLPRGEGLG-VPASGYEIHHGRITRGD--------TAEE 408 V GLGLL VE F P K +R G G VP GYEIHHGR+T D A+ Sbjct 361 --VPGLGLLPVEITFEPRKTVRRAEGTAAGDVPVHGYEIHHGRVTAADPGLAPLLRYADG 418 Query 409 FLGGARDGPVFGTMWHGSLEGDALREAFLRET--------LGLAPSGSCFLAARERRLDL 460 GAR G V+GT WHG+ DA R FL E +AP S F AARER LDL Sbjct 419 TGEGARLGTVYGTHWHGAFSSDAFRRRFLTEVAEAAGRTGFKVAPDTS-FAAARERTLDL 477 Query 461 LGDLVERHLDVDALLNL 477 LGDLVE HLD DAL L Sbjct 478 LGDLVEEHLDTDALWRL 494 >gi|269125539|ref|YP_003298909.1| cobyric acid synthase CobQ [Thermomonospora curvata DSM 43183] gi|268310497|gb|ACY96871.1| cobyric acid synthase CobQ [Thermomonospora curvata DSM 43183] Length=501 Score = 489 bits (1259), Expect = 4e-136, Method: Compositional matrix adjust. Identities = 297/504 (59%), Positives = 329/504 (66%), Gaps = 21/504 (4%) Query 1 MSG-LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIG 59 MSG LLVAGTTSDAGKS +TAGLCR L R+GV+VAPFKAQNMS NSMV G EIG Sbjct 1 MSGALLVAGTTSDAGKSVLTAGLCRWLVRQGVKVAPFKAQNMSLNSMVT----ADGAEIG 56 Query 60 RAQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAAC 119 RAQ +QA AAR P A MNP+LLKP D RS VVL+G+P EV + + A R L AA Sbjct 57 RAQAMQAQAARIEPTAHMNPILLKPGGDRRSQVVLLGRPVAEVDALGYGAHRDRLRRAAL 116 Query 120 RAFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFL 179 + L A YDVV+ EGAGSPAEINLRAGD NMGLAR AGLP +VVGDIDRGGVFAA Sbjct 117 ESLAHLRAEYDVVICEGAGSPAEINLRAGDIANMGLARAAGLPVLVVGDIDRGGVFAALY 176 Query 180 GTVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSED 239 GTV LL DQAL+AGFV+NKFRG +LL PGLR L +TGR VYG LPW L LD ED Sbjct 177 GTVGLLEPADQALIAGFVINKFRGAPELLEPGLRMLRDLTGRPVYGVLPWLDGLRLDVED 236 Query 240 ALDLQGRRAA-----GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDAD 294 +L L G AA G RVAVVRLPRISNFTDVDAL EP + V +A+ P L DAD Sbjct 237 SLGLDGPPAAAGPPHGAETLRVAVVRLPRISNFTDVDALACEPGVTVRYATAPGELADAD 296 Query 295 LIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPG 354 L+VLPG+RAT+ADLAWLR R L + G+P+LGICGG+QML I D +E Sbjct 297 LVVLPGSRATVADLAWLRERGLADQIAARARRGRPVLGICGGYQMLAEEIVDE--VESGA 354 Query 355 GQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGAR 414 G V GLGLL V F+ HK LR P G G P YEIHHG T AE FL G R Sbjct 355 GSVP---GLGLLPVRVEFARHKTLRRPVGTAYGHPVRAYEIHHGAATVTGPAEPFLDGCR 411 Query 415 DGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLDLLGDLVERH 468 G V+GT WHG+LE D R FLR A G F A RE RLD LGDLVERH Sbjct 412 VGAVWGTTWHGALESDGFRREFLRRVAEAAGRDFTPAPGVSFGALREARLDALGDLVERH 471 Query 469 LDVDALLNLARHGCPPTLPFLAPG 492 LD AL L G PP LP + PG Sbjct 472 LDTAALWRLIERGAPPDLPVVPPG 495 >gi|258650404|ref|YP_003199560.1| cobyric acid synthase [Nakamurella multipartita DSM 44233] gi|258553629|gb|ACV76571.1| cobyric acid synthase CobQ [Nakamurella multipartita DSM 44233] Length=486 Score = 486 bits (1251), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 277/487 (57%), Positives = 327/487 (68%), Gaps = 20/487 (4%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLL+AGT+SDAGKS VTAG+CR LAR+G+RVAPFKAQNMSNNSMVC G EIGRAQ Sbjct 10 GLLIAGTSSDAGKSLVTAGICRFLARQGLRVAPFKAQNMSNNSMVC----ADGSEIGRAQ 65 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 ++QA AA PE+AMNPVLLKP SD RS VV+ G+P G + S + +GRR LA+AA A+ Sbjct 66 YLQAQAAGAVPESAMNPVLLKPGSDRRSFVVVRGRPAGTLESGEFASGRRHLAQAAFAAY 125 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 LA RYDV+V EGAGSP EINLRAGDYVNMGLA+ LP +VVGDIDRGGVFA+ GTV Sbjct 126 RELAGRYDVIVCEGAGSPTEINLRAGDYVNMGLAQEFSLPVVVVGDIDRGGVFASLYGTV 185 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALD 242 ALL A DQAL+ G ++NKFRGD DLL PGL + ++TG V G LPW ++WLD ED L Sbjct 186 ALLDAADQALIRGLIINKFRGDVDLLRPGLDRIAQLTGVPVLGVLPWLTEVWLDGEDTLQ 245 Query 243 LQGRRAAGTGA----RRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVL 298 + GR A G RVA +R PR+SN TD+DAL EP ++V +DP + ADL+VL Sbjct 246 V-GRWGAPIGGPEPRLRVAALRFPRLSNVTDLDALACEPGVEVTMTADPGTIRAADLVVL 304 Query 299 PGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVT 358 PG+RAT+ADL WL A L A+ G P+LGICGGFQML R I DP +E G V+ Sbjct 305 PGSRATVADLTWLHASGLADAVRQAAGRGTPVLGICGGFQMLARTIDDP--VESGAGPVS 362 Query 359 EVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHG--RITRGDTAEEFLGGARDG 416 GLGLL V+ AF+P K L P G+ G GYEIHHG + G E FLGG R G Sbjct 363 ---GLGLLPVDVAFAPDKRLGTPAGDWQGHQVRGYEIHHGVATVAPGGGDESFLGGVRVG 419 Query 417 PVFGTMWHGSLEGDALREAFLRET----LGLAPSGSCFLAARERRLDLLGDLVERHLDVD 472 V+GTMWHG+ E D R A+LR + F A RE LD L D V HLD D Sbjct 420 SVWGTMWHGAFENDDFRRAWLRTATEGRFHADAAAPGFGARREAMLDRLADAVAEHLDTD 479 Query 473 ALLNLAR 479 ALL L R Sbjct 480 ALLALTR 486 >gi|284989156|ref|YP_003407710.1| cobyric acid synthase CobQ [Geodermatophilus obscurus DSM 43160] gi|284062401|gb|ADB73339.1| cobyric acid synthase CobQ [Geodermatophilus obscurus DSM 43160] Length=511 Score = 482 bits (1241), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 284/500 (57%), Positives = 324/500 (65%), Gaps = 20/500 (4%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQW 63 LLVAGTTSDAGKS VTAG+CR L R+GV VAPFKAQNMSNNSMV PDG EIGRAQ Sbjct 15 LLVAGTTSDAGKSVVTAGICRWLVRQGVSVAPFKAQNMSNNSMVT--PDGA--EIGRAQV 70 Query 64 VQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFD 123 +QA AAR PEAAMNPVLLKP + S VV++G +V + S+ + AL E + + Sbjct 71 MQAAAARVEPEAAMNPVLLKPGGEDSSQVVVLGHAVADVTALSYRPMKAALMEQVLASLE 130 Query 124 ALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVA 183 L +R+DVVV EGAGSP EINLRA D NMGLA AGLP +VVGDIDRGGVF A GTVA Sbjct 131 DLRSRFDVVVCEGAGSPTEINLRADDIANMGLATAAGLPVVVVGDIDRGGVFPALYGTVA 190 Query 184 LLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDL 243 L+ DQ LVAGF+VNKFRGD LL PGL L +TGR G LPW P +D ED+L + Sbjct 191 LMPPADQRLVAGFLVNKFRGDVRLLGPGLEQLTALTGRPTLGVLPWLPGAAVDVEDSLGV 250 Query 244 QGRRAA-----GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVL 298 + G RVAV RLPR+SNFTD+DAL EP + V +A+ P L DADL+VL Sbjct 251 PTGASPTGPPHGEEVLRVAVARLPRLSNFTDLDALAAEPGVLVRYATSPEELGDADLVVL 310 Query 299 PGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVT 358 PGTRAT+ADL WLRA L A+ H AAG+P+LG+CGG QML R I D +E G Sbjct 311 PGTRATVADLGWLRATGLADAVARHAAAGRPVLGVCGGSQMLARTITD--DVESRAGT-- 366 Query 359 EVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPV 418 V GLGLL + F+P K L P G G GYEIHHG + D AE FL GAR G V Sbjct 367 -VPGLGLLPADVRFAPEKTLGRPVGTAFGQEVRGYEIHHGVVIVDDAAERFLDGARAGSV 425 Query 419 FGTMWHGSLEGDALREAFLRETLG------LAPSGSCFLAARERRLDLLGDLVERHLDVD 472 FGT WHG+LEGD R AFL E +A + F A RERRLD LGDLV H D D Sbjct 426 FGTTWHGALEGDGFRRAFLTEVARVAGRRFVAAPDTDFAAVRERRLDALGDLVAEHADTD 485 Query 473 ALLNLARHGCPPTLPFLAPG 492 AL L G P LP L PG Sbjct 486 ALWRLVEDGVPAGLPLLPPG 505 >gi|271968632|ref|YP_003342828.1| adenosylcobyric acid synthase [Streptosporangium roseum DSM 43021] gi|270511807|gb|ACZ90085.1| adenosylcobyric acid synthase (glutamine- hydrolyzing) [Streptosporangium roseum DSM 43021] Length=509 Score = 482 bits (1241), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 284/502 (57%), Positives = 327/502 (66%), Gaps = 29/502 (5%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQW 63 LLVAGTTSDAGKS VTAG+CR LAR+GV+VAP+KAQNMS NS V G EIGRAQ Sbjct 5 LLVAGTTSDAGKSVVTAGICRWLARQGVKVAPYKAQNMSLNSFVT----ADGAEIGRAQA 60 Query 64 VQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFD 123 +QA A P A MNP+LLKP SD RS VV+MG+P +V + + + L + A A + Sbjct 61 MQAAACGLEPSADMNPILLKPGSDRRSQVVVMGRPLADVDAMEYWDVKDRLRQVAVDALE 120 Query 124 ALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVA 183 L YDVVV EGAGSPAEINLR GD NMGLAR A LP IVVGDIDRGGVFA+ GTVA Sbjct 121 RLRDTYDVVVCEGAGSPAEINLRRGDIANMGLARAASLPVIVVGDIDRGGVFASLYGTVA 180 Query 184 LLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDL 243 LL DQAL+AGFV+NKFRG +LL PGL + +TGR VYG LPW LWLD ED+L L Sbjct 181 LLEPADQALIAGFVINKFRGARELLEPGLDMIRDLTGREVYGVLPWLDGLWLDVEDSLAL 240 Query 244 QGRRAAGT------GARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 R A G RVAVVRLPRISNFTDVDAL EP + V F + P LDDADL+V Sbjct 241 DNRPAIGARTPYGRQTLRVAVVRLPRISNFTDVDALASEPGVVVRFVTSPAELDDADLVV 300 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPG+RAT++DLAWLRA L AL G+ +LGICGG+QML R I D G+E G+ Sbjct 301 LPGSRATVSDLAWLRATGLADAL-----RGRVVLGICGGYQMLARTIHD--GVESGAGR- 352 Query 358 TEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGP 417 VEGLGLL F+ K L P GE G + YEIHHG +T + + FL G R G Sbjct 353 --VEGLGLLPATVEFAAEKTLGRPVGEAYGCRVAAYEIHHGVVT-AEGGDPFLDGCRSGS 409 Query 418 VFGTMWHGSLEGDALREAFLRETLGL-------APSGSCFLAARERRLDLLGDLVERHLD 470 V+GT WHG+LE D R AFL + + AP S F A RE RLD LGDL+E H+D Sbjct 410 VWGTTWHGALENDDFRRAFLADVAAVSGRDFTPAPDVS-FAALREERLDALGDLIEHHVD 468 Query 471 VDALLNLARHGCPPTLPFLAPG 492 ALL L G P LP L PG Sbjct 469 TAALLRLLEGGAPRGLPLLPPG 490 >gi|340774431|gb|EGR96918.1| cobyric acid synthase CobQ [Propionibacterium acnes SK182B-JCVI] Length=486 Score = 480 bits (1236), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 264/490 (54%), Positives = 328/490 (67%), Gaps = 19/490 (3%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 MSG+LVAGT+SDAGKS V LCRA RRG+ V P+KAQNMSNNSMVC PDG+ EIGR Sbjct 1 MSGILVAGTSSDAGKSLVVTALCRAAWRRGIDVVPYKAQNMSNNSMVC--PDGS--EIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQ++QA AAR TPE+AMNPVLLKP +D RS +VL G P G + + + GRR LAEAA Sbjct 57 AQYLQASAARVTPESAMNPVLLKPGTDRRSFIVLRGTPGGVLEAGQYATGRRHLAEAAWA 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 A+D L+A +D+V+ EGAGSPAEINLRAGDY NMGLAR LP ++VGDIDRGGV A+ G Sbjct 117 AYDELSAAHDMVICEGAGSPAEINLRAGDYTNMGLAREKSLPVVLVGDIDRGGVLASLFG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T ALL D++L+AG+V+NKFRGD +LAPGL ++ R TG +G LPW P++WLD EDA Sbjct 177 TWALLDDADRSLLAGYVINKFRGDESVLAPGLEEITRRTGMPSFGVLPWVPEVWLDGEDA 236 Query 241 LDLQGRRAAGTGAR----RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLI 296 L++ R G RVAVVRLPRISN TDVDA+ E +DV ++P + AD++ Sbjct 237 LEVGRWRHDGNSVSTDDLRVAVVRLPRISNATDVDAMAAEAGVDVQVTTNPNTCELADVL 296 Query 297 VLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQ 356 VLPG+R+T+ DL WLR+ + + G+ +LGICGG+QML R+I DP G E P Sbjct 297 VLPGSRSTVRDLEWLRSTGIAEVVARRARQGRTVLGICGGYQMLTRLILDPEGQESP--- 353 Query 357 VTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTA-EEFLGGARD 415 EGLGLL VE F K L +P G G+ GYEIHHGR+ +A E FL G R Sbjct 354 TERTEGLGLLPVEVTFGADKTLAIPSGSWRGIEVGGYEIHHGRMDVDLSAGEPFLDGVRV 413 Query 416 GPVFGTMWHGSLEGDALREAFLRETLGLAPS-------GSCFLAARERRLDLLGDLVERH 468 G V+GTMWHG+ E D R A+L E A S + RE+ +D+L D VE H Sbjct 414 GSVWGTMWHGAFECDDFRRAWLAEAAEHAGSAWRPVEGAIGYGQRREQMIDVLADAVEEH 473 Query 469 LDVDALLNLA 478 L +D L +LA Sbjct 474 LGLDRLFSLA 483 >gi|315504103|ref|YP_004082990.1| cobyric acid synthase cobq [Micromonospora sp. L5] gi|315410722|gb|ADU08839.1| cobyric acid synthase CobQ [Micromonospora sp. L5] Length=514 Score = 479 bits (1233), Expect = 5e-133, Method: Compositional matrix adjust. Identities = 296/497 (60%), Positives = 330/497 (67%), Gaps = 28/497 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS +TAG+CR L RRGVRVAPFKAQNMSNNS V GPDG G E+GRAQ Sbjct 4 GLLVAGTTSDAGKSVLTAGICRWLRRRGVRVAPFKAQNMSNNSAVVVGPDGRGGELGRAQ 63 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 +QA A + NPVLLKP SDH S VVL+G+ V + ++ R LA A A Sbjct 64 AMQAAACGLDADLRFNPVLLKPGSDHASQVVLLGEAVDTVTAGNYHEVRSRLATTAYAAL 123 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 L + YDVV+ EGAGSPAEINLR GDYVNMGLAR AGLPTIVVGDIDRGGVFA+ GTV Sbjct 124 AELRSEYDVVICEGAGSPAEINLRDGDYVNMGLARQAGLPTIVVGDIDRGGVFASMFGTV 183 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL- 241 ALL A DQAL+AGFVVNKFRGD LL PGL L RVTGR YG +PW DLWLD+ED+L Sbjct 184 ALLDAADQALLAGFVVNKFRGDRGLLQPGLDMLRRVTGRPTYGVVPWALDLWLDAEDSLA 243 Query 242 --DLQGRRAA--GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 + GR A GT VAVVRLPRISN TDV+AL EP + V +P L ADL+V Sbjct 244 YGRVLGRPPAPRGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADLVV 303 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPGT++T+ADLAWLR L A+ H AAG+PLLGICGGFQMLGR I D +E G Sbjct 304 LPGTKSTVADLAWLRETGLADAVRAHAAAGRPLLGICGGFQMLGRAIHD--AVESRRGT- 360 Query 358 TEVEGLGLLDVETAFSPHKVLRLPRGEGLG-VPASGYEIHHGRITRGD--------TAEE 408 V GLGLL VE F P K +R G G VP GYEIHHGR+T D A+ Sbjct 361 --VPGLGLLPVEITFEPRKTVRRAEGTAAGDVPVHGYEIHHGRVTAADPGLAPLLRYADG 418 Query 409 FLGGARDGPVFGTMWHGSLEGDALREAFLRET--------LGLAPSGSCFLAARERRLDL 460 GAR G V+GT WHG+ DA R FL E +AP S F AA ER LDL Sbjct 419 TGEGARLGTVYGTHWHGAFSSDAFRRRFLTEVAEAAGRTGFKVAPDTS-FAAAGERTLDL 477 Query 461 LGDLVERHLDVDALLNL 477 LGDLVE HLD DAL L Sbjct 478 LGDLVEEHLDTDALWRL 494 >gi|145596066|ref|YP_001160363.1| cobyric acid synthase CobQ [Salinispora tropica CNB-440] gi|145305403|gb|ABP55985.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Salinispora tropica CNB-440] Length=521 Score = 477 bits (1227), Expect = 3e-132, Method: Compositional matrix adjust. Identities = 291/497 (59%), Positives = 326/497 (66%), Gaps = 28/497 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLV GTTSDAGKS +TAG+CR L R+GVRVAPFKAQNMSNNS V GPDG G EIGRAQ Sbjct 4 GLLVTGTTSDAGKSVLTAGICRWLHRQGVRVAPFKAQNMSNNSAVVVGPDGHGGEIGRAQ 63 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAF 122 +QA A P+ NPVLLKP SD S VVL+G+ + + ++ R LAE A A Sbjct 64 AMQAAACGLAPDLRFNPVLLKPGSDRSSQVVLLGEAVDTLTTDTFRQLRPRLAETAYAAL 123 Query 123 DALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTV 182 L YDVV+ EGAGSP EINLRAGDYVNMGLARHA LP IVVGDIDRGGVFA+ GTV Sbjct 124 AELRTSYDVVICEGAGSPTEINLRAGDYVNMGLARHADLPAIVVGDIDRGGVFASMFGTV 183 Query 183 ALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL- 241 ALL DQALVAGFV+NKFRGD LLAPGL L +VTGR YG LPW DLWLD+ED+L Sbjct 184 ALLEPADQALVAGFVINKFRGDRGLLAPGLDMLRQVTGRPTYGVLPWALDLWLDAEDSLA 243 Query 242 --DLQGRRAAGTGAR--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIV 297 + GR AA G+ VAVVRLPRISN TDV+AL EP + V +P L ADL+V Sbjct 244 YGRVLGRPAAPRGSDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAADLVV 303 Query 298 LPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQV 357 LPG+++T+ADLAWLR L A+L H AAG+PLLGICGGFQMLGR I DP +E G Sbjct 304 LPGSKSTVADLAWLRQNGLADAVLAHAAAGRPLLGICGGFQMLGRRIHDP--VESGQGS- 360 Query 358 TEVEGLGLLDVETAFSPHKVLRLPRGEGL-GVPASGYEIHHGRITRG--DTAEEFL---- 410 V GLGLL VE F P K +R G G GVP GYEIHHG ++ D A F Sbjct 361 --VPGLGLLPVEVTFKPSKTVRQSAGTGWDGVPVRGYEIHHGYVSAAAPDLAPLFTYADG 418 Query 411 --GGARDGPVFGTMWHGSLEGDALREAFLRET--------LGLAPSGSCFLAARERRLDL 460 G G V+GT WHG+ E D R FL E AP S F ARER LDL Sbjct 419 TGEGVAAGAVYGTHWHGAFESDGFRRRFLTEVARQAGRPGFRAAPDTS-FAGARERSLDL 477 Query 461 LGDLVERHLDVDALLNL 477 LGDLVE HLD L L Sbjct 478 LGDLVEEHLDTAVLWRL 494 >gi|312194369|ref|YP_004014430.1| cobyric acid synthase CobQ [Frankia sp. EuI1c] gi|311225705|gb|ADP78560.1| cobyric acid synthase CobQ [Frankia sp. EuI1c] Length=532 Score = 476 bits (1224), Expect = 6e-132, Method: Compositional matrix adjust. Identities = 287/504 (57%), Positives = 326/504 (65%), Gaps = 20/504 (3%) Query 1 MSG-LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIG 59 MSG LLVAGTTSDAGKS +TAG+CR LAR+GVRVAPFKAQNMS NS V G EIG Sbjct 1 MSGALLVAGTTSDAGKSVLTAGICRWLARQGVRVAPFKAQNMSLNSWVT----ADGAEIG 56 Query 60 RAQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAAC 119 RAQ +QA AA PE AMNPVLLKP + HRS VVL G+P E + + A + L Sbjct 57 RAQVMQAAAAGVEPEGAMNPVLLKPGAGHRSQVVLRGRPVAEAGALDYRALKGRLFTEVL 116 Query 120 RAFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFL 179 + L +R+DVV+ EGAGSPAEINLRA D NMGLAR A LPT+VVGDIDRGGVFAA Sbjct 117 ASLADLRSRFDVVICEGAGSPAEINLRADDIANMGLARAARLPTLVVGDIDRGGVFAAMF 176 Query 180 GTVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSED 239 GT+ALL DQALVAGFVVNKFRG+ LL PGL L +TGR V G LPW L LD ED Sbjct 177 GTLALLEPADQALVAGFVVNKFRGERALLEPGLGMLSGLTGRPVLGVLPWRDGLGLDVED 236 Query 240 ALDLQG---RRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLI 296 +L L G R G RVA VRLP +SNFTD+DAL EP + V + P LD ADL+ Sbjct 237 SLGLPGPGETRGDLDGTLRVAAVRLPFLSNFTDLDALAAEPGVAVRYVDRPEDLDAADLV 296 Query 297 VLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQ 356 VLPGTR+T+ADLAWLR R LD L A G+P+LG+CGG+QML I D +E G+ Sbjct 297 VLPGTRSTVADLAWLRGRRLDGPLARRAATGRPVLGVCGGYQMLAETIVDE--VESGAGR 354 Query 357 VTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDG 416 V+GLGLL V F+ K L P G G P GYEIHHG + E FL G R G Sbjct 355 ---VDGLGLLPVTIRFAAAKTLGRPDGVAYGQPVRGYEIHHG-VASVHGGEPFLDGCRAG 410 Query 417 PVFGTMWHGSLEGDALREAFLRETLG-----LAPSGSC-FLAARERRLDLLGDLVERHLD 470 V+GT WHG+ E D R AFL + P G F A RERRLD+LGDLV HLD Sbjct 411 AVWGTTWHGAFENDGFRRAFLADVAARVGSPWQPRGEVSFAAVRERRLDVLGDLVAEHLD 470 Query 471 VDALLNLARHGCPPTLPFLAPGAP 494 DALL L G P LPF+ PGAP Sbjct 471 TDALLRLLADGPPAGLPFIPPGAP 494 >gi|317123947|ref|YP_004098059.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Intrasporangium calvum DSM 43043] gi|315588035|gb|ADU47332.1| adenosylcobyric acid synthase (glutamine-hydrolysing) [Intrasporangium calvum DSM 43043] Length=511 Score = 471 bits (1212), Expect = 1e-130, Method: Compositional matrix adjust. Identities = 282/514 (55%), Positives = 331/514 (65%), Gaps = 43/514 (8%) Query 2 SGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRA 61 SG+LVAGT+SDAGKS V AGLCRALARRGVRVAPFKAQNMSNNSMVC G EIGRA Sbjct 4 SGVLVAGTSSDAGKSVVVAGLCRALARRGVRVAPFKAQNMSNNSMVC----ADGGEIGRA 59 Query 62 QWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRA 121 Q++QA AAR P AMNPVLLKP +D RS VV+ G+P G + + + AGR L +AA A Sbjct 60 QYLQARAARVEPTTAMNPVLLKPGTDRRSFVVVRGQPAGTLEAGEYAAGRAHLRDAAFAA 119 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 + LA Y++VV EGAGSPAEINLRAGDYVN+GLAR GLP +VVGDIDRGG+ AA GT Sbjct 120 YRELADEYELVVCEGAGSPAEINLRAGDYVNLGLAREFGLPVVVVGDIDRGGILAALYGT 179 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 ALL D+AL+ FV+NKFRGD +L PGL ++ R TG +G +PW D+WLDSED L Sbjct 180 WALLDDGDRALLKSFVINKFRGDVAVLEPGLEEITRRTGVPFHGVIPWLLDVWLDSEDTL 239 Query 242 DLQGRRAAGT---GAR---RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADL 295 ++ RA+ + AR RVAV+RLPRISN TDVDAL EP +DV+ DP D ADL Sbjct 240 EVGHWRASTSLSATARDRLRVAVLRLPRISNATDVDALAAEPGVDVLVTVDPAVCDAADL 299 Query 296 IVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGG 355 +VLPG+R+T DLAWLR R L + AAG+P+LGICGG+QM I D +E G Sbjct 300 LVLPGSRSTAGDLAWLRERGLAEVVARRAAAGRPVLGICGGYQMFAEAIED--DVE---G 354 Query 356 QVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASG-YEIHH-------GRITRGDT-- 405 QV V GL LL F KVL P G G P G YEIHH G T G T Sbjct 355 QVGVVPGLALLPTTVEFRAEKVLGRPSGSWRGHPVEGAYEIHHGIAHPTVGSCTPGATGS 414 Query 406 -----------AEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLGLA-------PSG 447 E FLGG R G V+GTMWHG+ E D R A+L E G+A P Sbjct 415 PPTSSVHFVPPVEAFLGGWRAGAVWGTMWHGAFESDDFRRAWLGEVAGVAGSLWRPQPGA 474 Query 448 SCFLAARERRLDLLGDLVERHLDVDALLNLARHG 481 F A RE+ LD L D +E H+D+DALL L R G Sbjct 475 PSFAARREQMLDTLADALEEHVDIDALLALTRVG 508 >gi|294628671|ref|ZP_06707231.1| cobyric acid synthase CobQ [Streptomyces sp. e14] gi|292832004|gb|EFF90353.1| cobyric acid synthase CobQ [Streptomyces sp. e14] Length=502 Score = 470 bits (1210), Expect = 2e-130, Method: Compositional matrix adjust. Identities = 277/508 (55%), Positives = 319/508 (63%), Gaps = 26/508 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR L R+GV+VAPFKAQNMS NS V R G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 59 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRR-ALAEAACRA 121 +QA A R P A MNPVLLKP + S VVL+GKP GE+++ + GR+ L Sbjct 60 AMQAQACRIEPTALMNPVLLKPGGEQSSQVVLLGKPVGELSARGYHGGRQQKLLGTVLDC 119 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L YD V+ EGAGSPAEINLR D VNMG+AR A LP +VVGDIDRGGVFA+F GT Sbjct 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGARLPVLVVGDIDRGGVFASFFGT 179 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 +ALL+ EDQ LVAGF+VNKFRGD LL PGL L +TGR YG LP+ L +D ED L Sbjct 180 LALLSPEDQELVAGFLVNKFRGDVSLLEPGLDMLHGLTGRHTYGVLPFRHGLGIDEEDGL 239 Query 242 DLQGRRA---------AGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 + R A G RVAV +P +SNFTDVDAL EP + V F P L D Sbjct 240 RVSLRGAVRESVVAAPVGEDVLRVAVCAIPLMSNFTDVDALAAEPGVVVRFVDRPEELAD 299 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+V+PGTR T+ L WLR R L AL+ A G+P+LG+CGGFQ+LG I D +E Sbjct 300 ADLVVVPGTRGTVRALRWLRERGLADALVRRAAEGRPVLGVCGGFQILGERIEDD--VES 357 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGG 412 G V GLGLL V F+ K L P G LG P GYEIHHG T + E FL G Sbjct 358 RAGAVA---GLGLLPVRVRFAREKTLTRPSGHALGEPVEGYEIHHGVATV-EGGEPFLDG 413 Query 413 ARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLDLLGDLVE 466 R G V+GT WHGSLE D R AFLRE A + F A RE +LD LGDL+E Sbjct 414 CRVGAVWGTHWHGSLESDGFRRAFLREVAAAAGRRFTPAPDTSFAALREEQLDRLGDLIE 473 Query 467 RHLDVDALLNLARHGCPPTLPFLAPGAP 494 +H D DAL L G P LPF+ PGAP Sbjct 474 QHADTDALWRLIESGAPQGLPFIPPGAP 501 >gi|288918655|ref|ZP_06413003.1| cobyric acid synthase CobQ [Frankia sp. EUN1f] gi|288349953|gb|EFC84182.1| cobyric acid synthase CobQ [Frankia sp. EUN1f] Length=525 Score = 470 bits (1210), Expect = 2e-130, Method: Compositional matrix adjust. Identities = 284/502 (57%), Positives = 322/502 (65%), Gaps = 19/502 (3%) Query 2 SGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRA 61 + LLVAGTTSDAGKS VTAG+CR LAR+GVRVAPFKAQNMS NS V G EIGRA Sbjct 13 NALLVAGTTSDAGKSVVTAGICRFLARQGVRVAPFKAQNMSLNSWVT----ADGAEIGRA 68 Query 62 QWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRA 121 Q +QA AA PEAAMNPVLLKP + HRS VVL G+P E + + + L + Sbjct 69 QVMQAAAAGIEPEAAMNPVLLKPGARHRSQVVLRGRPVAETGALDYRELKGRLFTEVLAS 128 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L +R+DVVV EGAGSPAEINLRA D NMGLAR AGLP IVVGDIDRGGVFAA GT Sbjct 129 LADLRSRFDVVVCEGAGSPAEINLRANDIANMGLARAAGLPAIVVGDIDRGGVFAAMYGT 188 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 +ALL DQALVAGFVVNKFRG+ LL PGL L +TGR V G LPW L LD ED+L Sbjct 189 LALLEPADQALVAGFVVNKFRGERALLEPGLDMLRGLTGRPVLGVLPWQDGLDLDVEDSL 248 Query 242 DLQG---RRAAGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVL 298 L R G RVA VRLP +SNFTD+DAL EP + V +A P LD ADL+VL Sbjct 249 GLPAPGETRGDPAGPLRVAAVRLPFLSNFTDLDALAAEPGVAVRYADRPEDLDAADLVVL 308 Query 299 PGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVT 358 PGTR+T+ADL WLR R L AL A+G+P+LG+CGG+QML I D +E +V Sbjct 309 PGTRSTVADLGWLRRRGLHGALARRAASGRPVLGVCGGYQMLAATIVDE--VE---SRVG 363 Query 359 EVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGGARDGPV 418 ++GLGLL V F+ K L P G G P GYEIHHG T E FL G R G V Sbjct 364 AIDGLGLLPVTVRFAADKTLGRPVGVAYGQPVRGYEIHHGVATV-HGGEPFLDGCRAGAV 422 Query 419 FGTMWHGSLEGDALREAFLRETLG-----LAPSGS-CFLAARERRLDLLGDLVERHLDVD 472 +GT WHG+ E D R AFL + P G F A RERRLD+LGDLV HLD Sbjct 423 WGTTWHGAFENDGFRRAFLTDVAARTGSPWQPRGEISFAAVRERRLDVLGDLVADHLDTG 482 Query 473 ALLNLARHGCPPTLPFLAPGAP 494 AL L G P LPF+ PGAP Sbjct 483 ALRALLADGPPAGLPFVPPGAP 504 >gi|297198773|ref|ZP_06916170.1| cobyric acid synthase CobQ [Streptomyces sviceus ATCC 29083] gi|297147203|gb|EFH28528.1| cobyric acid synthase CobQ [Streptomyces sviceus ATCC 29083] Length=503 Score = 470 bits (1209), Expect = 3e-130, Method: Compositional matrix adjust. Identities = 278/508 (55%), Positives = 323/508 (64%), Gaps = 26/508 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR L R+GV+VAPFKAQNMS NS V R G EIGRAQ Sbjct 5 GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 60 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRR-ALAEAACRA 121 +QA A R P A MNPVLLKP + S VVL+GKP GE+++ + GR+ L Sbjct 61 AMQAQACRVEPTALMNPVLLKPGGEQSSQVVLLGKPVGELSARGYHGGRQQKLLGTVLDC 120 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L YD V+ EGAGSPAEINLR D VNMG+AR+A +P +VVGDIDRGGVFA+F GT Sbjct 121 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARNARIPVLVVGDIDRGGVFASFFGT 180 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALL+ EDQALVAGF+VNKFRGD LL PGL L +TGR YG LP+ L +D ED L Sbjct 181 VALLSPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRSTYGVLPFRHGLGIDEEDGL 240 Query 242 --DLQG--RRAA-----GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 L+G R +A G RVAV +P +SNFTDVDAL EP + V F P L D Sbjct 241 RVSLRGTVRESAVSPPVGEDVLRVAVCAIPLMSNFTDVDALAAEPGVVVRFVDRPEELAD 300 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+V+PGTR T+ L WLR R L AL+ A G+P+LG+CGGFQ+LG I D +E Sbjct 301 ADLVVVPGTRGTVRALEWLRERGLADALVRRAAEGRPVLGVCGGFQILGEHIEDD--VES 358 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGG 412 G VEGLG+L V F+ K L P GE LG GYEIHHG + E FL G Sbjct 359 RQGH---VEGLGVLPVRVWFAREKTLTRPVGEALGEQVEGYEIHHG-VADVSGGEPFLDG 414 Query 413 ARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLDLLGDLVE 466 R G +GT WHGSLE D R AFLRE A + F A RE +LD LGDL+E Sbjct 415 CRVGQTWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAPDTSFAALREEQLDRLGDLIE 474 Query 467 RHLDVDALLNLARHGCPPTLPFLAPGAP 494 +H D DAL L G P LPF+ PGAP Sbjct 475 QHADTDALWRLIESGAPQGLPFIPPGAP 502 >gi|302561367|ref|ZP_07313709.1| cobyric acid synthase CobQ [Streptomyces griseoflavus Tu4000] gi|302478985|gb|EFL42078.1| cobyric acid synthase CobQ [Streptomyces griseoflavus Tu4000] Length=511 Score = 469 bits (1208), Expect = 4e-130, Method: Compositional matrix adjust. Identities = 276/515 (54%), Positives = 321/515 (63%), Gaps = 32/515 (6%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR LAR+GV+VAPFKAQNMS NS V R G EIGRAQ Sbjct 5 GLLVAGTTSDAGKSVVTAGICRWLARQGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 60 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRA-LAEAACRA 121 +QA A R P A MNPVLLKP + S VVLMG+P GE+ + + GRR L Sbjct 61 AMQAQACRVEPTALMNPVLLKPGGEQSSQVVLMGRPVGEMTARGYHGGRRQRLLGTVLDC 120 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 + L YD V+ EGAGSPAEINLR D VNMG+AR+AGLP +VVGDIDRGGVFA+F GT Sbjct 121 LEQLRGTYDAVICEGAGSPAEINLRRTDIVNMGIARNAGLPVLVVGDIDRGGVFASFFGT 180 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALL+ DQ LVAGF+VNKFRGD LL PGL L +TGRR YG LP+ L +D ED L Sbjct 181 VALLSRTDQELVAGFLVNKFRGDVSLLEPGLEMLHGLTGRRTYGVLPFRHGLGIDEEDGL 240 Query 242 DLQGRRAA---------GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 + R A G RVAV +P +SNFTDVDAL EP + V F P L D Sbjct 241 RVSLRGAVRESAVAAPLGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRPEELVD 300 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+V+PGTR T+ L WLR R L AL A G+P+LGICGG+Q+LG + D +E Sbjct 301 ADLVVVPGTRGTVRALDWLRERGLADALRRRAAEGRPVLGICGGYQLLGESVEDD--VES 358 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHH-------GRITRGDT 405 G+ V+GLG+L V F+ K L P GE LG P GYEIHH G + D Sbjct 359 RRGR---VDGLGILPVRVRFAREKTLTRPVGEALGEPVEGYEIHHGVAEVLGGEVFISDD 415 Query 406 AEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLD 459 L G R G +GT WHGSLE D R AFLR+ A + F A RE +LD Sbjct 416 RGRGLDGCRVGKTWGTHWHGSLESDRFRRAFLRKVAAAAGRRFVPAPDTSFAALREEQLD 475 Query 460 LLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 LGDL+E+H D DAL L G P LPF+ PGAP Sbjct 476 RLGDLIEQHADTDALWRLIESGAPQGLPFIPPGAP 510 >gi|302550524|ref|ZP_07302866.1| cobyric acid synthase CobQ [Streptomyces viridochromogenes DSM 40736] gi|302468142|gb|EFL31235.1| cobyric acid synthase CobQ [Streptomyces viridochromogenes DSM 40736] Length=502 Score = 467 bits (1202), Expect = 2e-129, Method: Compositional matrix adjust. Identities = 276/508 (55%), Positives = 315/508 (63%), Gaps = 26/508 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR L R+GV+VAPFKAQNMS NS V R G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 59 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRR-ALAEAACRA 121 +QA A R P A MNPVLLKP + S VVLMGKP GE+++ + GR+ L Sbjct 60 AMQAQACRVEPTALMNPVLLKPGGERSSQVVLMGKPVGELSARGYHGGRQQKLLGTVLDC 119 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L YD V+ EGAGSPAEINLR D VNMG+AR A LP +VVGDIDRGGVFA+F GT Sbjct 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGARLPVLVVGDIDRGGVFASFFGT 179 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALL+ EDQ LVAGF+VNKFRGD LL PGL L +TGR YG LP+ L +D ED L Sbjct 180 VALLSPEDQELVAGFLVNKFRGDVSLLEPGLDMLHGLTGRHTYGVLPFRHGLGIDEEDGL 239 Query 242 DLQGRRA---------AGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 + R G R+AV +P +SNFTDVDAL EP V F P L D Sbjct 240 RVSLRGTVRESTVAPPVGEDVLRIAVCAIPLMSNFTDVDALAAEPGAVVRFVDRPEELAD 299 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+V+PGTR T+ L WL R L AL VA G+P+LG+CGGFQ+LG I D +E Sbjct 300 ADLVVVPGTRGTVRALEWLHERGLAEALKRRVAEGRPVLGVCGGFQVLGEHIEDD--VES 357 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGG 412 G VEGLG+L V F+ K L P GE LG GYEIHHG I E FL G Sbjct 358 RKGS---VEGLGVLPVRVRFAAEKTLTRPVGEALGERVEGYEIHHG-IAEVTGGEPFLDG 413 Query 413 ARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLDLLGDLVE 466 R G +GT WHGSLE D R AFLRE A + F A RE +LD LGDL+E Sbjct 414 CRVGQTWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAPDTSFAALREEQLDRLGDLIE 473 Query 467 RHLDVDALLNLARHGCPPTLPFLAPGAP 494 +H D DAL L G P LPF+ PGAP Sbjct 474 QHADTDALWRLIESGAPRGLPFIPPGAP 501 >gi|289772432|ref|ZP_06531810.1| cobyric acid synthase CobQ [Streptomyces lividans TK24] gi|289702631|gb|EFD70060.1| cobyric acid synthase CobQ [Streptomyces lividans TK24] Length=502 Score = 466 bits (1199), Expect = 4e-129, Method: Compositional matrix adjust. Identities = 277/508 (55%), Positives = 320/508 (63%), Gaps = 26/508 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR L R+GV+VAPFKAQNMS NS V R G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTR----DGAEIGRAQ 59 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRA-LAEAACRA 121 +QA A R P A MNPVLLKP + S VVL+G+P GE+++ + GR+ L + Sbjct 60 AMQAQACRVEPTAHMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQERLLGTVLDS 119 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L YD V+ EGAGSPAEINLR D VNMG+AR AGLP +VVGDIDRGGVFA+F GT Sbjct 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGAGLPVLVVGDIDRGGVFASFFGT 179 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALLA EDQALVAGF+VNKFRGD LL PGL L +TGRR YG LP+ L +D ED L Sbjct 180 VALLAPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPFRHGLGIDEEDGL 239 Query 242 --DLQG--RRAA-----GTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 L+G R +A G RVAV +P +SNFTDVDAL EP + V F P L D Sbjct 240 RVSLRGTVRESAVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRPEELAD 299 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+++PGTR T+ L WLR R L A+ +P+LGICGG+Q+LG I D +E Sbjct 300 ADLVIVPGTRGTVRALEWLRERGLADAIARRATERRPVLGICGGYQLLGEHIEDE--VES 357 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGG 412 G V+GLGLL V F K L P GE LG P GYEIHHG + FL G Sbjct 358 RAGH---VDGLGLLPVRVRFDREKTLTRPVGEALGEPVEGYEIHHG-VAEVTGGAPFLDG 413 Query 413 ARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLDLLGDLVE 466 R G +GT WHGSLE D R AFLRE A + F A RE +LD LGDL+E Sbjct 414 CRVGRTWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAPDTSFAALREEQLDRLGDLIE 473 Query 467 RHLDVDALLNLARHGCPPTLPFLAPGAP 494 H D DAL L G P LPF+ PGAP Sbjct 474 HHADTDALWRLIESGAPQGLPFIPPGAP 501 >gi|311899006|dbj|BAJ31414.1| putative cobyric acid synthase [Kitasatospora setae KM-6054] Length=516 Score = 466 bits (1198), Expect = 5e-129, Method: Compositional matrix adjust. Identities = 297/512 (59%), Positives = 337/512 (66%), Gaps = 30/512 (5%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQW 63 LLVAGTTSDAGKS VTAG+CR LAR+GVRVAPFKAQNMS NS V G EIGRAQ Sbjct 5 LLVAGTTSDAGKSVVTAGICRWLARQGVRVAPFKAQNMSLNSFVT----ADGAEIGRAQA 60 Query 64 VQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFD 123 +QA AA PEAAMNPVLLKP +D RS VVL+G+ EV + + + L E A Sbjct 61 MQAQAAGVAPEAAMNPVLLKPGADGRSQVVLLGRAVAEVGALDYRDRKPVLLERALECLA 120 Query 124 ALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVA 183 L +R+DVVV EGAGSPAEINLR D NMGLA A LP +VVGDIDRGGVFA+ GT+A Sbjct 121 DLRSRFDVVVCEGAGSPAEINLRDRDIANMGLASAARLPVVVVGDIDRGGVFASMFGTLA 180 Query 184 LLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDL 243 LL+ +DQ+LVAG+ VNKFRGD+ LLAPGL L +TGR V GT P P LWLD+ED+LDL Sbjct 181 LLSPDDQSLVAGWFVNKFRGDARLLAPGLEMLRGLTGRPVLGTFPMLPGLWLDAEDSLDL 240 Query 244 ---QGRRAAG--TGAR--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLI 296 R +AG GA+ RVAVVRLPR+SNFTDVDAL EP + V +A+ P L DADL+ Sbjct 241 ASVAARPSAGGPVGAQVLRVAVVRLPRLSNFTDVDALAQEPGVLVRWATRPEELADADLV 300 Query 297 VLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQ 356 VLPGTRAT+ADLAWLRAR L L VAAG P+LG+CGG+QMLGR I D + G Sbjct 301 VLPGTRATVADLAWLRARGLAEPLAARVAAGLPVLGVCGGYQMLGREIVDAVESKSSG-- 358 Query 357 VTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRIT-------RGDTAEEF 409 V GLGLL F KVL P G LG GYEIHHG + D A Sbjct 359 --PVAGLGLLPTRVVFGAEKVLARPAGVALGERVEGYEIHHGVVAVEGGEPFVTDDAGRP 416 Query 410 LGGARDGPVFGTMWHGSLEGDALREAFLRETLGL-------APSGSCFLAARERRLDLLG 462 L G R GPV+GT WHG LE DA R AFL E AP S F AARE++LD LG Sbjct 417 LDGCRLGPVWGTTWHGVLENDAFRRAFLAEAARAAGRAFVPAPDTS-FAAAREQQLDALG 475 Query 463 DLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 DLV H D DAL L +G P LPF+ PGAP Sbjct 476 DLVAEHADTDALWKLIENGAPAGLPFVPPGAP 507 >gi|328881543|emb|CCA54782.1| Cobyric acid synthase [Streptomyces venezuelae ATCC 10712] Length=502 Score = 465 bits (1197), Expect = 8e-129, Method: Compositional matrix adjust. Identities = 280/508 (56%), Positives = 323/508 (64%), Gaps = 26/508 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR L R+G++VAPFK QNMS NS V R G EIGRAQ Sbjct 5 GLLVAGTTSDAGKSVVTAGICRWLVRQGIKVAPFKGQNMSLNSFVTR----EGAEIGRAQ 60 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGR-RALAEAACRA 121 +QA AAR P A MNPVLLKP SD S VVLMGKP GE+++ + GR + L E Sbjct 61 AMQAQAARVEPTALMNPVLLKPGSDRSSQVVLMGKPVGELSARGYHGGRQKELFEPVLAC 120 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 + L + YD V+ EGAGSPAEINLR D VNMG+AR A LP +VVGDIDRGGVFA F GT Sbjct 121 LEELRSTYDAVICEGAGSPAEINLRRTDIVNMGIARAARLPVVVVGDIDRGGVFAQFFGT 180 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 ALLA EDQ L+AG++VNKFRGD LL PGL L +TGRR +G LP+ L +D ED L Sbjct 181 TALLAPEDQELIAGYLVNKFRGDVTLLEPGLDMLHGLTGRRTFGVLPYAHGLGIDEEDGL 240 Query 242 DLQGRRA---------AGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 + R A G RVAV +P +SNFTDVDAL EP + V F L D Sbjct 241 RVSLRGAVRESVVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELVD 300 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+V+PGTR T+ LAWLR R L AL+ A G+P+LG+CGGFQ+LG I D +E Sbjct 301 ADLVVVPGTRGTVRALAWLRERGLADALVRRAAEGRPVLGVCGGFQVLGEHIEDE--VES 358 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGG 412 G V+GLGLL V F+P K L P GE LG GYEIHHG + E FL G Sbjct 359 KAGA---VDGLGLLPVRVRFAPGKTLARPVGEALGERVEGYEIHHG-VADVRGGEPFLDG 414 Query 413 ARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PSGSCFLAARERRLDLLGDLVE 466 R G V+GT WHGSLE D R AFLRE A + F A RE +LD LGDL+E Sbjct 415 CRVGAVWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAPDTSFGALREEQLDRLGDLIE 474 Query 467 RHLDVDALLNLARHGCPPTLPFLAPGAP 494 H D DALL L G P LPF+ PGAP Sbjct 475 EHADTDALLRLIEQGPPKGLPFVPPGAP 502 >gi|290961437|ref|YP_003492619.1| cobyric acid synthase [Streptomyces scabiei 87.22] gi|260650963|emb|CBG74081.1| cobyric acid synthase [Streptomyces scabiei 87.22] Length=508 Score = 465 bits (1197), Expect = 8e-129, Method: Compositional matrix adjust. Identities = 277/510 (55%), Positives = 319/510 (63%), Gaps = 30/510 (5%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR L R+GV+VAPFKAQNMS NS V + G EIGRAQ Sbjct 4 GLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTK----EGAEIGRAQ 59 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRA-LAEAACRA 121 +QA A R P A MNPVLLKP + S VVL+G+P GE+++ + GR+ L Sbjct 60 AMQAQACRVEPTALMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQQRLLGTVLDC 119 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L YD V+ EGAGSPAEINLR D VNMG+AR+AGLP +VVGDIDRGGVFA+F GT Sbjct 120 LAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARNAGLPVLVVGDIDRGGVFASFFGT 179 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALL+ EDQALVAGF+VNKFRGD LL PGL L +TGRR YG LP+ L +D ED L Sbjct 180 VALLSPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPFRHGLGIDEEDGL 239 Query 242 DLQGRRA---------AGTGARRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDD 292 + R G RVAV +P +SNFTDVDAL EP + V F L D Sbjct 240 RVSLRGTVRESNVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELAD 299 Query 293 ADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEG 352 ADL+V+PGTR T+ L WLR R L ALL A G+P+LGICGGFQ+LG I D +E Sbjct 300 ADLVVVPGTRGTVRALEWLRERGLAEALLRRAAEGRPVLGICGGFQLLGEHIEDD--VES 357 Query 353 PGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLGG 412 G V LG+L V F+ K L P GE LG GYEIHHG + E FL G Sbjct 358 RQGHVP---ALGVLPVRVRFAEDKTLTRPAGEALGERVEGYEIHHG-VAEVLGGEPFLDG 413 Query 413 ARDGPVFGTMWHGSLEGDALREAFLRETLGLAPSG--------SCFLAARERRLDLLGDL 464 R G +GT WHGSLE D R AFLRE A SG + F A RE +LD LGDL Sbjct 414 CRVGQTWGTHWHGSLESDGFRRAFLREV--AAASGRRFVPAPDTSFAALREEQLDRLGDL 471 Query 465 VERHLDVDALLNLARHGCPPTLPFLAPGAP 494 +E H D DAL L G P LPF+ PGAP Sbjct 472 IEEHADTDALWRLIESGAPAGLPFVPPGAP 501 >gi|134102427|ref|YP_001108088.1| cobyric acid synthase [Saccharopolyspora erythraea NRRL 2338] gi|291004187|ref|ZP_06562160.1| cobyric acid synthase [Saccharopolyspora erythraea NRRL 2338] gi|187470828|sp|A4FM88.1|COBQ_SACEN RecName: Full=Cobyric acid synthase gi|133915050|emb|CAM05163.1| cobyric acid synthase [Saccharopolyspora erythraea NRRL 2338] Length=519 Score = 464 bits (1194), Expect = 1e-128, Method: Compositional matrix adjust. Identities = 282/519 (55%), Positives = 326/519 (63%), Gaps = 39/519 (7%) Query 1 MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGR 60 M+ LL+AGTTSDAGKS V AG+CR LAR G RVAPFKAQNMSNNS+V PDG EIGR Sbjct 1 MNALLIAGTTSDAGKSVVAAGVCRWLARTGARVAPFKAQNMSNNSVVT--PDGG--EIGR 56 Query 61 AQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACR 120 AQ VQA A P NPVLLKP SD RS VV++G GEV + S+ + AL + Sbjct 57 AQAVQAAACGLEPSVRFNPVLLKPGSDRRSQVVVLGHVSGEVTAMSYRERKAALLDTVVS 116 Query 121 AFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLG 180 D L A +D V+ EGAGSPAEINLRA D NMGLAR AGLP +VVGDIDRGGVFA G Sbjct 117 TLDGLRAEHDHVICEGAGSPAEINLRATDIANMGLARAAGLPVLVVGDIDRGGVFAQLFG 176 Query 181 TVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDA 240 T+ALL A DQALV GFV+NKFRGD LL GL L +TGR V+G LPW DLWLD+ED+ Sbjct 177 TLALLDAADQALVGGFVINKFRGDPALLDSGLDRLRALTGRPVHGVLPWAEDLWLDAEDS 236 Query 241 LD-----LQGRRAAGTGAR--RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDA 293 L + GR A G++ RVAV RLPRISN TDV+AL EP + V F ++P L DA Sbjct 237 LSYVADGVVGRPAPPRGSQWLRVAVPRLPRISNATDVEALAAEPGVAVRFVTEPSRLTDA 296 Query 294 DLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGP 353 DL+VLPG+++T+ADL WL L A+ H AG P++GICGGFQML R I D +E Sbjct 297 DLVVLPGSKSTVADLGWLHDTGLADAIRAHAGAGLPVVGICGGFQMLTRRITDQ--VE-- 352 Query 354 GGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHG-RITRGD-------- 404 V V+GLG+LD+E F K LR P G G P GYEIHHG + RGD Sbjct 353 -SGVGAVDGLGMLDLEIEFEEAKTLRRPSGTAFGEPVDGYEIHHGVPVRRGDDLAGLVRL 411 Query 405 ---TAEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLG-------LAPSGSCFLAAR 454 TAE G G V GT WHG E DA R FL G +A + F R Sbjct 412 PGGTAE----GGLSGSVAGTHWHGLFENDAFRRRFLTWAAGCAGRDGFVAAGDTSFAEVR 467 Query 455 ERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGA 493 +LDLLGDLVE+HLD DA+ L G P LP L PGA Sbjct 468 AGQLDLLGDLVEKHLDTDAIRRLLEGGAPAGLPLLPPGA 506 >gi|336116044|ref|YP_004570810.1| cobyric acid synthase [Microlunatus phosphovorus NM-1] gi|334683822|dbj|BAK33407.1| cobyric acid synthase [Microlunatus phosphovorus NM-1] Length=531 Score = 464 bits (1194), Expect = 1e-128, Method: Compositional matrix adjust. Identities = 271/509 (54%), Positives = 331/509 (66%), Gaps = 29/509 (5%) Query 2 SGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRA 61 SG+L+AGT+SDAGKS V GLCRALARRG+ VAPFKAQNMSNNSMVC G EIGRA Sbjct 7 SGVLIAGTSSDAGKSLVVTGLCRALARRGINVAPFKAQNMSNNSMVC----ADGSEIGRA 62 Query 62 QWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRA 121 Q +QA AA P +AMNPVLLKP SD RS VVL GKP+G + + + GR ALAEAA A Sbjct 63 QHLQAQAAGAEPTSAMNPVLLKPGSDRRSFVVLRGKPYGTLEAGQYATGRAALAEAAFAA 122 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 + LAA +D+V+ EGAGSPAEINLR GDYVN+GLAR LP I+VGDIDRGGVFA+ GT Sbjct 123 YQELAAAHDLVICEGAGSPAEINLRTGDYVNLGLARRFKLPMIIVGDIDRGGVFASLYGT 182 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 ALL D+A + G+V+NKFRGD +L PGL L TG G LPW P++WLD+ED L Sbjct 183 YALLDDADRATLRGYVINKFRGDQSILQPGLEMLTERTGLVGLGVLPWLPNVWLDAEDTL 242 Query 242 DLQGRRAA--GTGAR---RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLI 296 ++ R++ +G R RVAVVRLPR+SN TDV+AL EP +DV+ +DPR + DADL+ Sbjct 243 EVGAWRSSPRASGDRDRLRVAVVRLPRVSNITDVEALAAEPGVDVLVTTDPRVVADADLV 302 Query 297 VLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQ 356 VLPGTR T++DL WLR ++ A++ + G+P+LGICGG+Q+L R I D +E G Sbjct 303 VLPGTRTTVSDLTWLRETEIAEAVMGRASQGRPVLGICGGYQLLAREIDDK--LESGDGA 360 Query 357 VTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHG--RITRGDTAEEFLGGAR 414 + GLGLL + FS KVL P G G P + YEIHHG G AE+FL G R Sbjct 361 TS---GLGLLPIHVTFSDDKVLGRPVGSWRGHPVAAYEIHHGVAEPIDGTDAEQFLDGWR 417 Query 415 DGPVFGTMWHGSLEGDALREAFLRETLGLAPSGS---------CFLAARERRLDLLGDLV 465 +GTMWHG+LE D R A+L E A SGS F RE + + D V Sbjct 418 SRQTWGTMWHGTLENDDFRRAWLTEV--AAASGSDWRPRQDAPAFAERRETMITTMADAV 475 Query 466 ERHLDVDALLNLARHGCPPTLPFLAPGAP 494 E HLD+D LL+ PT P P Sbjct 476 EEHLDLDRLLSWTT--ARPTKPNFWRKTP 502 >gi|329940747|ref|ZP_08290027.1| cobyric acid synthase [Streptomyces griseoaurantiacus M045] gi|329300041|gb|EGG43939.1| cobyric acid synthase [Streptomyces griseoaurantiacus M045] Length=531 Score = 463 bits (1191), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 279/528 (53%), Positives = 325/528 (62%), Gaps = 45/528 (8%) Query 3 GLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQ 62 GLLVAGTTSDAGKS VTAG+CR LAR+GV+VAPFKAQNMS NS V R G EIGRAQ Sbjct 12 GLLVAGTTSDAGKSVVTAGICRWLARQGVKVAPFKAQNMSLNSFVTR----EGAEIGRAQ 67 Query 63 WVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGR-RALAEAACRA 121 +QA A R P A MNPVLLKP + S VVL+G+P GE+++ + GR R L A Sbjct 68 AMQAQACRIEPTALMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQRELLSVVLDA 127 Query 122 FDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGT 181 L A +D V+ EGAGSPAEINLR D VNMG+AR+A LP +VVGDIDRGGVFA+F GT Sbjct 128 LAELRATHDAVICEGAGSPAEINLRRTDIVNMGIARNAKLPVLVVGDIDRGGVFASFFGT 187 Query 182 VALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDAL 241 VALL+ +DQ LVAGF+VNKFRGD LL PGL L +TGR YG LP+ L +D ED + Sbjct 188 VALLSRKDQELVAGFLVNKFRGDVSLLEPGLDMLHGLTGRSTYGVLPFRHGLGIDEEDGM 247 Query 242 DLQGRRA----------------------AGTGARRVAVVRLPRISNFTDVDALGLEPDL 279 + R G RVAV LP +SNFTDVDAL EP + Sbjct 248 GVPPARTKVRAGGRISLRGTVRESDTAPPVGEDVLRVAVCALPLMSNFTDVDALAAEPGV 307 Query 280 DVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQM 339 V F P L DADL+++PGTR T+ L WLR R L AL A G+P+LGICGGFQ+ Sbjct 308 LVRFVDRPEELADADLVIVPGTRGTVRALEWLRERGLADALRRRAAEGRPVLGICGGFQI 367 Query 340 LGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHG- 398 LG I D +E G+ V+GLGLL V F+ K L P G LG A GYEIHHG Sbjct 368 LGEQIEDE--VESRAGR---VDGLGLLPVRVRFAREKTLARPVGRALGERAEGYEIHHGV 422 Query 399 -RITRGDT-----AEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLGLA------PS 446 +T GD A + L G R G V GT WHGSLE D R A+LRE A Sbjct 423 AEVTGGDPFFSDGAGQALDGCRVGAVRGTHWHGSLESDGFRRAYLREVAAAAGRRFVPAP 482 Query 447 GSCFLAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP 494 +CF A RE +LD LGDL+E+H D DAL L G P LPF+ PGAP Sbjct 483 DTCFAALREEQLDRLGDLIEQHADTDALWRLIESGAPRGLPFIPPGAP 530 >gi|296139407|ref|YP_003646650.1| cobyric acid synthase CobQ [Tsukamurella paurometabola DSM 20162] gi|296027541|gb|ADG78311.1| cobyric acid synthase CobQ [Tsukamurella paurometabola DSM 20162] Length=507 Score = 462 bits (1190), Expect = 5e-128, Method: Compositional matrix adjust. Identities = 258/484 (54%), Positives = 316/484 (66%), Gaps = 14/484 (2%) Query 4 LLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNNSMVCRGPDGTGVEIGRAQW 63 LL+AG TSDAGKS +TAGLCR LARRGVRVAPFKAQNMSNNS+ DGT EIGRAQ Sbjct 5 LLIAGATSDAGKSTITAGLCRLLARRGVRVAPFKAQNMSNNSVATVETDGTSGEIGRAQA 64 Query 64 VQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEVASSSWCAGRRALAEAACRAFD 123 QALA P NPVLLKP SD RS ++L G+P G+V + + R+ L + Sbjct 65 TQALACGLAPSTRFNPVLLKPGSDRRSQLILHGRPVGDVGARDYITRRQWLLDEVTTTLQ 124 Query 124 ALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFAAFLGTVA 183 L +DVV+ EGAGSPAEINLRA D NMGLAR AGLPT+VVGDIDRGGV A GTVA Sbjct 125 RLRDEFDVVLCEGAGSPAEINLRATDIANMGLARAAGLPTVVVGDIDRGGVLAHLAGTVA 184 Query 184 LLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERVTGRRVYGTLPWHPDLWLDSEDALDL 243 +L +DQ + F++N+FRGD LL PGL LE +T R G LP+ DLWLD+ED+L Sbjct 185 VLDPDDQRHIYAFLINRFRGDVSLLTPGLEQLEDITRRPTVGVLPYLTDLWLDAEDSLAA 244 Query 244 QGRRAAGTGAR-----RVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRALDDADLIVL 298 G G G+R RVA + LPR+SN TDV+AL EP L V + + P + ADL+VL Sbjct 245 LGSDLVGPGSRRPDPLRVAAIALPRVSNTTDVEALACEPGLTVRWTTRPADVAAADLVVL 304 Query 299 PGTRATIADLAWLRARDLDRALLVHVAAGKPLLGICGGFQMLGRVIRDPYGIEGPGGQVT 358 PGT+AT+ADLAWLR R L AL+ A G+P++G+CGG+QMLGR I DP+GIE P G + Sbjct 305 PGTKATVADLAWLRERGLADALVARAAGGRPIIGVCGGYQMLGRSIGDPHGIEAPVG--S 362 Query 359 EVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASGYEIHHGRITRGDTAEEFLG-----GA 413 V+GLGLLD++ F+ K +R G GLGV A+GYEIHHG + R + G GA Sbjct 363 RVDGLGLLDLDIEFAADKCVRNVAGTGLGVRATGYEIHHGTVVRSTESHLLDGPDGAEGA 422 Query 414 RDGPVFGTMWHGSLEGDALREAFLRETL-GLAPSG-SCFLAARERRLDLLGDLVERHLDV 471 GPV GT WHG L D R A+L G P + + AR +LD + D +E H DV Sbjct 423 LAGPVLGTHWHGLLGSDEFRRAYLHRAFPGFDPGPVTSYDGARIAQLDRIADAIEEHCDV 482 Query 472 DALL 475 DA++ Sbjct 483 DAIV 486 Lambda K H 0.321 0.139 0.425 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1059382658600 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40