BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0270
Length=560
Score E
Sequences producing significant alignments: (Bits) Value
gi|15607411|ref|NP_214784.1| acyl-CoA synthetase [Mycobacterium ... 1122 0.0
gi|298523738|ref|ZP_07011147.1| acyl-CoA synthetase [Mycobacteri... 1122 0.0
gi|121636183|ref|YP_976406.1| acyl-CoA synthetase [Mycobacterium... 1121 0.0
gi|289441647|ref|ZP_06431391.1| fatty-acid-CoA ligase fadD2 [Myc... 1120 0.0
gi|336460177|gb|EGO39082.1| acyl-CoA synthetase (AMP-forming)/AM... 937 0.0
gi|254777332|ref|ZP_05218848.1| acyl-CoA synthetase [Mycobacteri... 935 0.0
gi|118462477|ref|YP_884012.1| acyl-CoA synthetase [Mycobacterium... 934 0.0
gi|41409812|ref|NP_962648.1| acyl-CoA synthetase [Mycobacterium ... 934 0.0
gi|254820797|ref|ZP_05225798.1| acyl-CoA synthetase [Mycobacteri... 931 0.0
gi|342859259|ref|ZP_08715913.1| acyl-CoA synthetase [Mycobacteri... 930 0.0
gi|183980556|ref|YP_001848847.1| fatty-acid-CoA ligase FadD2 [My... 929 0.0
gi|118616906|ref|YP_905238.1| acyl-CoA synthetase [Mycobacterium... 924 0.0
gi|296167546|ref|ZP_06849898.1| acyl-CoA synthetase [Mycobacteri... 906 0.0
gi|333988898|ref|YP_004521512.1| fatty-acid-CoA ligase [Mycobact... 898 0.0
gi|240168488|ref|ZP_04747147.1| acyl-CoA synthetase [Mycobacteri... 897 0.0
gi|15828369|ref|NP_302632.1| acyl-CoA synthetase [Mycobacterium ... 895 0.0
gi|120401422|ref|YP_951251.1| acyl-CoA synthetase [Mycobacterium... 891 0.0
gi|145220945|ref|YP_001131623.1| acyl-CoA synthetase [Mycobacter... 880 0.0
gi|118473796|ref|YP_885010.1| acyl-CoA synthetase [Mycobacterium... 859 0.0
gi|108797341|ref|YP_637538.1| acyl-CoA synthetase [Mycobacterium... 854 0.0
gi|126432963|ref|YP_001068654.1| acyl-CoA synthetase [Mycobacter... 852 0.0
gi|169631417|ref|YP_001705066.1| acyl-CoA synthetase [Mycobacter... 746 0.0
gi|284041810|ref|YP_003392150.1| AMP-dependent synthetase and li... 570 3e-160
gi|54025764|ref|YP_120006.1| acyl-CoA synthetase [Nocardia farci... 505 1e-140
gi|284045146|ref|YP_003395486.1| AMP-dependent synthetase and li... 475 7e-132
gi|333920077|ref|YP_004493658.1| AMP-dependent synthetase and li... 452 8e-125
gi|119716227|ref|YP_923192.1| AMP-dependent synthetase and ligas... 443 5e-122
gi|302529170|ref|ZP_07281512.1| O-succinylbenzoate-CoA ligase [S... 441 2e-121
gi|257055386|ref|YP_003133218.1| acyl-CoA synthetase [Saccharomo... 437 2e-120
gi|161598438|ref|YP_120711.2| acyl-CoA synthetase [Nocardia farc... 437 3e-120
gi|300788812|ref|YP_003769103.1| fatty-acyl-CoA synthase [Amycol... 436 5e-120
gi|54017977|dbj|BAD59347.1| putative acyl-CoA synthetase [Nocard... 436 6e-120
gi|134098931|ref|YP_001104592.1| acyl-CoA synthase [Saccharopoly... 430 3e-118
gi|326330577|ref|ZP_08196884.1| substrate--CoA ligase [Nocardioi... 430 4e-118
gi|54026470|ref|YP_120712.1| acyl-CoA synthetase [Nocardia farci... 427 2e-117
gi|108800723|ref|YP_640920.1| acyl-CoA synthetase [Mycobacterium... 423 4e-116
gi|311744718|ref|ZP_07718515.1| acyl-CoA synthetase [Aeromicrobi... 422 7e-116
gi|126436346|ref|YP_001072037.1| acyl-CoA synthetase [Mycobacter... 422 8e-116
gi|317507848|ref|ZP_07965549.1| AMP-binding enzyme [Segniliparus... 421 1e-115
gi|269124818|ref|YP_003298188.1| AMP-dependent synthetase and li... 421 1e-115
gi|296392903|ref|YP_003657787.1| AMP-dependent synthetase and li... 415 1e-113
gi|111023360|ref|YP_706332.1| acyl-CoA synthetase [Rhodococcus j... 414 2e-113
gi|254818395|ref|ZP_05223396.1| acyl-CoA synthetase [Mycobacteri... 413 4e-113
gi|226305728|ref|YP_002765688.1| fatty-acid--CoA ligase [Rhodoco... 413 4e-113
gi|333918709|ref|YP_004492290.1| acyl-CoA synthetase [Amycolicic... 413 5e-113
gi|226365862|ref|YP_002783645.1| acyl-CoA synthetase [Rhodococcu... 411 2e-112
gi|134097880|ref|YP_001103541.1| acyl-CoA synthase [Saccharopoly... 409 6e-112
gi|291007402|ref|ZP_06565375.1| acyl-CoA synthase [Saccharopolys... 409 7e-112
gi|333920255|ref|YP_004493836.1| AMP-dependent synthetase and li... 409 8e-112
gi|339298042|gb|AEJ50152.1| acyl-CoA synthetase [Mycobacterium t... 409 8e-112
>gi|15607411|ref|NP_214784.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Rv]
gi|15839651|ref|NP_334688.1| acyl-CoA synthetase [Mycobacterium tuberculosis CDC1551]
gi|31791448|ref|NP_853941.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97]
64 more sequence titles
Length=560
Score = 1122 bits (2903), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 560/560 (100%), Positives = 560/560 (100%), Gaps = 0/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW
Sbjct 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN
Sbjct 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG
Sbjct 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN
Sbjct 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL
Sbjct 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG
Sbjct 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG
Sbjct 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF
Sbjct 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGKVLKRELRKL
Sbjct 541 LDELPRNPTGKVLKRELRKL 560
>gi|298523738|ref|ZP_07011147.1| acyl-CoA synthetase [Mycobacterium tuberculosis 94_M4241A]
gi|298493532|gb|EFI28826.1| acyl-CoA synthetase [Mycobacterium tuberculosis 94_M4241A]
Length=560
Score = 1122 bits (2901), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 559/560 (99%), Positives = 560/560 (100%), Gaps = 0/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW
Sbjct 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GEVGMLPSHNARRAPNRAAV+DEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN
Sbjct 61 GEVGMLPSHNARRAPNRAAVMDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG
Sbjct 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN
Sbjct 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL
Sbjct 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG
Sbjct 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG
Sbjct 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF
Sbjct 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGKVLKRELRKL
Sbjct 541 LDELPRNPTGKVLKRELRKL 560
>gi|121636183|ref|YP_976406.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Pasteur 1173P2]
gi|224988656|ref|YP_002643343.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172]
gi|121491830|emb|CAL70292.1| Probable fatty-acid-CoA ligase fadD2 [Mycobacterium bovis BCG
str. Pasteur 1173P2]
gi|224771769|dbj|BAH24575.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172]
gi|341600199|emb|CCC62868.1| probable fatty-acid-CoA ligase fadD2 [Mycobacterium bovis BCG
str. Moreau RDJ]
Length=560
Score = 1121 bits (2900), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 559/560 (99%), Positives = 560/560 (100%), Gaps = 0/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW
Sbjct 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAG+GVAILARN
Sbjct 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGEGVAILARN 120
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG
Sbjct 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN
Sbjct 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL
Sbjct 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG
Sbjct 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG
Sbjct 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF
Sbjct 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGKVLKRELRKL
Sbjct 541 LDELPRNPTGKVLKRELRKL 560
>gi|289441647|ref|ZP_06431391.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T46]
gi|289568180|ref|ZP_06448407.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T17]
gi|289748751|ref|ZP_06508129.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T92]
gi|289756337|ref|ZP_06515715.1| substrate-CoA ligase [Mycobacterium tuberculosis EAS054]
gi|289414566|gb|EFD11806.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T46]
gi|289541933|gb|EFD45582.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T17]
gi|289689338|gb|EFD56767.1| fatty-acid-CoA ligase fadD2 [Mycobacterium tuberculosis T92]
gi|289696924|gb|EFD64353.1| substrate-CoA ligase [Mycobacterium tuberculosis EAS054]
Length=560
Score = 1120 bits (2898), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 559/560 (99%), Positives = 559/560 (99%), Gaps = 0/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW
Sbjct 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN
Sbjct 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG
Sbjct 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN
Sbjct 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL
Sbjct 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG
Sbjct 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG
Sbjct 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVE L
Sbjct 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEGL 480
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF
Sbjct 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGKVLKRELRKL
Sbjct 541 LDELPRNPTGKVLKRELRKL 560
>gi|336460177|gb|EGO39082.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium
avium subsp. paratuberculosis S397]
Length=565
Score = 937 bits (2421), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 472/560 (85%), Positives = 510/560 (92%), Gaps = 1/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQA + K + QYV RG+AELHYLR+IIESGA LEPP NYAA+AADI KW
Sbjct 5 MPNLLGLPGQATKAVAK-VQQYVERGSAELHYLRRIIESGAFRLEPPQNYAAMAADIYKW 63
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P RAAVIDEEG L+++ELD AAHAVANGL+AKGV+AGDGVAILARN
Sbjct 64 GEFGMLPSLNARRTPGRAAVIDEEGELSYAELDRAAHAVANGLIAKGVKAGDGVAILARN 123
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYGAARVGARIILLNSEFSGPQIKEVS+REGAKVIIYDDEYTKAVS A+PPLG
Sbjct 124 HRWFLIANYGAARVGARIILLNSEFSGPQIKEVSEREGAKVIIYDDEYTKAVSKAEPPLG 183
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALG NPD D+PSGS+DETLAELI HSS+ PAPKA R ASIIILTSGTTGTPKGANR+
Sbjct 184 KLRALGTNPDADEPSGSTDETLAELIEHSSSEPAPKADRHASIIILTSGTTGTPKGANRS 243
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKAGEVT LPSPMFHALGY+HA +AMFLGSTLVLRR+FKP LVL
Sbjct 244 TPPTLAPVGGILSHVPFKAGEVTSLPSPMFHALGYLHATIAMFLGSTLVLRRKFKPPLVL 303
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
+DIEK++ T+MVVVPVMLSRILD LEK + KPDLSSL+IVFVSGSQLGAELA RAL D+G
Sbjct 304 QDIEKYRPTAMVVVPVMLSRILDTLEKMDKKPDLSSLRIVFVSGSQLGAELAARALKDIG 363
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGPKDL+ N +TVGPVVKGV VKI D+NG E+PQG VGRIFVG
Sbjct 364 PVIYNMYGSTEIAFATIAGPKDLERNAATVGPVVKGVKVKIFDDNGKELPQGEVGRIFVG 423
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
N FPF GYTGGG KQIIDGLLSSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 424 NTFPFAGYTGGGNKQIIDGLLSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDL 483
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA AIGV+DKE+G RLRAFVVKK GADLDEDTIK YVRDHL RYKVPREVIF
Sbjct 484 ISGHPDVVEATAIGVEDKEWGHRLRAFVVKKEGADLDEDTIKHYVRDHLVRYKVPREVIF 543
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 544 LDELPRNPTGKILKRELREM 563
>gi|254777332|ref|ZP_05218848.1| acyl-CoA synthetase [Mycobacterium avium subsp. avium ATCC 25291]
Length=561
Score = 935 bits (2417), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 472/560 (85%), Positives = 511/560 (92%), Gaps = 1/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQA + K + QYV RG+AELHYLR+IIESGA LEPP NYAA+AADI KW
Sbjct 1 MPNLLGLPGQATKAVAK-VQQYVERGSAELHYLRRIIESGAFRLEPPQNYAAMAADIYKW 59
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P+RAAVIDEEG L+++ELD AAHAVANGL+AKGV+AGDGVAILARN
Sbjct 60 GEFGMLPSLNARRTPDRAAVIDEEGELSYAELDRAAHAVANGLIAKGVKAGDGVAILARN 119
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYGAARVGARIILLNSEFSGPQIKEVS+REGAKVIIYDDEYTKAVS A+PPLG
Sbjct 120 HRWFLIANYGAARVGARIILLNSEFSGPQIKEVSEREGAKVIIYDDEYTKAVSKAEPPLG 179
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALG NPD D+PSGS+DETLAELI SS+ PAPKA R ASIIILTSGTTGTPKGANR+
Sbjct 180 KLRALGTNPDADEPSGSTDETLAELIERSSSEPAPKADRHASIIILTSGTTGTPKGANRS 239
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKAGEVT LPSPMFHALGY+HA +AMFLGSTLVLRR+FKP LVL
Sbjct 240 TPPTLAPVGGILSHVPFKAGEVTSLPSPMFHALGYLHATIAMFLGSTLVLRRKFKPPLVL 299
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
+DIEK++ T+MVVVPVMLSRILD LEK + KPDLSSL+IVFVSGSQLGAELA RAL D+G
Sbjct 300 QDIEKYRPTAMVVVPVMLSRILDTLEKMDKKPDLSSLRIVFVSGSQLGAELAARALKDIG 359
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGPKDL+ N +TVGPVVKGV VKI D+NG E+PQG VGRIFVG
Sbjct 360 PVIYNMYGSTEIAFATIAGPKDLERNAATVGPVVKGVKVKIFDDNGKELPQGEVGRIFVG 419
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
N FPF GYTGGG KQIIDGLLSSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 420 NTFPFAGYTGGGNKQIIDGLLSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDL 479
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA AIGV+DKE+G RLRAFVVKK GADLDEDTIK YVRDHLARYKVPREVIF
Sbjct 480 ISGHPDVVEATAIGVEDKEWGHRLRAFVVKKEGADLDEDTIKHYVRDHLARYKVPREVIF 539
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 540 LDELPRNPTGKILKRELREM 559
>gi|118462477|ref|YP_884012.1| acyl-CoA synthetase [Mycobacterium avium 104]
gi|118163764|gb|ABK64661.1| acyl-CoA synthase [Mycobacterium avium 104]
Length=561
Score = 934 bits (2415), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 472/560 (85%), Positives = 511/560 (92%), Gaps = 1/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQA + K + QYV RG+AELHYLR+IIESGA LEPP NYAA+AADI KW
Sbjct 1 MPNLLGLPGQATKAVAK-VQQYVERGSAELHYLRRIIESGAFRLEPPQNYAAMAADIYKW 59
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P+RAAVIDEEG L+++ELD AAHAVANGL+AKGV+AGDGVAILARN
Sbjct 60 GEFGMLPSLNARRTPDRAAVIDEEGELSYAELDRAAHAVANGLIAKGVKAGDGVAILARN 119
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYGAARVGARIILLNSEFSGPQIKEVS+REGAKVIIYDDEYTKAVS A+PPLG
Sbjct 120 HRWFLIANYGAARVGARIILLNSEFSGPQIKEVSEREGAKVIIYDDEYTKAVSKAEPPLG 179
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALG NPD D+PSGS+DETLAELI SS+ PAPKA R ASIIILTSGTTGTPKGANR+
Sbjct 180 KLRALGSNPDADEPSGSTDETLAELIERSSSEPAPKADRHASIIILTSGTTGTPKGANRS 239
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKAGEVT LPSPMFHALGY+HA +AMFLGSTLVLRR+FKP LVL
Sbjct 240 TPPTLAPVGGILSHVPFKAGEVTSLPSPMFHALGYLHATIAMFLGSTLVLRRKFKPPLVL 299
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
+DIEK++ T+MVVVPVMLSRILD LEK + KPDLSSL+IVFVSGSQLGAELA RAL D+G
Sbjct 300 QDIEKYRPTAMVVVPVMLSRILDTLEKMDKKPDLSSLRIVFVSGSQLGAELAARALKDIG 359
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGPKDL+ N +TVGPVVKGV VKI D+NG E+PQG VGRIFVG
Sbjct 360 PVIYNMYGSTEIAFATIAGPKDLERNAATVGPVVKGVKVKIFDDNGKELPQGEVGRIFVG 419
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
N FPF GYTGGG KQIIDGLLSSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 420 NTFPFAGYTGGGNKQIIDGLLSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDL 479
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA AIGV+DKE+G RLRAFVVKK GADLDEDTIK YVRDHLARYKVPREVIF
Sbjct 480 ISGHPDVVEATAIGVEDKEWGHRLRAFVVKKEGADLDEDTIKHYVRDHLARYKVPREVIF 539
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 540 LDELPRNPTGKILKRELREM 559
>gi|41409812|ref|NP_962648.1| acyl-CoA synthetase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398644|gb|AAS06264.1| FadD2 [Mycobacterium avium subsp. paratuberculosis K-10]
Length=561
Score = 934 bits (2414), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 472/560 (85%), Positives = 510/560 (92%), Gaps = 1/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQA + K + QYV RG+AELHYLR+IIESGA LEPP NYAA+AADI KW
Sbjct 1 MPNLLGLPGQATKAVAK-VQQYVERGSAELHYLRRIIESGAFRLEPPQNYAAMAADIYKW 59
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P RAAVIDEEG L+++ELD AAHAVANGL+AKGV+AGDGVAILARN
Sbjct 60 GEFGMLPSLNARRTPGRAAVIDEEGELSYAELDRAAHAVANGLIAKGVKAGDGVAILARN 119
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYGAARVGARIILLNSEFSGPQIKEVS+REGAKVIIYDDEYTKAVS A+PPLG
Sbjct 120 HRWFLIANYGAARVGARIILLNSEFSGPQIKEVSEREGAKVIIYDDEYTKAVSKAEPPLG 179
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALG NPD D+PSGS+DETLAELI HSS+ PAPKA R ASIIILTSGTTGTPKGANR+
Sbjct 180 KLRALGTNPDADEPSGSTDETLAELIEHSSSEPAPKADRHASIIILTSGTTGTPKGANRS 239
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKAGEVT LPSPMFHALGY+HA +AMFLGSTLVLRR+FKP LVL
Sbjct 240 TPPTLAPVGGILSHVPFKAGEVTSLPSPMFHALGYLHATIAMFLGSTLVLRRKFKPPLVL 299
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
+DIEK++ T+MVVVPVMLSRILD LEK + KPDLSSL+IVFVSGSQLGAELA RAL D+G
Sbjct 300 QDIEKYRPTAMVVVPVMLSRILDTLEKMDKKPDLSSLRIVFVSGSQLGAELAARALKDIG 359
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGPKDL+ N +TVGPVVKGV VKI D+NG E+PQG V RIFVG
Sbjct 360 PVIYNMYGSTEIAFATIAGPKDLERNAATVGPVVKGVKVKIFDDNGKELPQGEVVRIFVG 419
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
N FPF GYTGGG KQIIDGLLSSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 420 NTFPFAGYTGGGNKQIIDGLLSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDL 479
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA AIGV+DKE+G RLRAFVVKK GADLDEDTIK YVRDHLARYKVPREVIF
Sbjct 480 ISGHPDVVEATAIGVEDKEWGHRLRAFVVKKEGADLDEDTIKHYVRDHLARYKVPREVIF 539
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 540 LDELPRNPTGKILKRELREM 559
>gi|254820797|ref|ZP_05225798.1| acyl-CoA synthetase [Mycobacterium intracellulare ATCC 13950]
Length=562
Score = 931 bits (2406), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 458/560 (82%), Positives = 501/560 (90%), Gaps = 1/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQA SK + QYV RG+AELHY+RKI ESGA +EPP NYAA+AADI KW
Sbjct 1 MPNLLGLPGQA-SKAVAKLHQYVERGSAELHYVRKIFESGAFRIEPPQNYAAMAADIYKW 59
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLP+ NARR P+RAA IDEEG ++ ELDEAAHAVANGL+ KGV+ GDGVAILARN
Sbjct 60 GEFGMLPALNARRHPDRAACIDEEGEFSYRELDEAAHAVANGLIEKGVKGGDGVAILARN 119
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
RWF+IANYGAARVGARIILLNSEFSGPQIKEVS+REGAK+IIYDDEY KAVS A P LG
Sbjct 120 TRWFLIANYGAARVGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYAKAVSKASPELG 179
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALG NPD D+PSGS+DETLA+LI SS PAPKA+R ASIIILTSGTTGTPKGANR+
Sbjct 180 KLRALGTNPDSDEPSGSTDETLADLIERSSKEPAPKAARHASIIILTSGTTGTPKGANRS 239
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKAGEVT LP+PMFHALGY+H +AMFLGSTLVLRR+FKP LVL
Sbjct 240 TPPTLAPVGGILSHVPFKAGEVTSLPAPMFHALGYLHGTIAMFLGSTLVLRRKFKPPLVL 299
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
+DIEK+K T+MVVVPVMLSRIL+ +EK + KPDLSSLKIVFVSGS LGA+LA R+L DLG
Sbjct 300 QDIEKYKVTAMVVVPVMLSRILEAVEKMDSKPDLSSLKIVFVSGSALGADLAERSLKDLG 359
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIA PK LQ+N STVGPVVKGV VKI D+NG E+PQG VGRIFVG
Sbjct 360 PVIYNMYGSTEIAFATIAEPKHLQYNSSTVGPVVKGVRVKIYDDNGKELPQGEVGRIFVG 419
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGG KQIIDGLLSSGDVGYFDE GLLY+SGRDDEMIVSGGENVFPAEVEDL
Sbjct 420 NAFPFEGYTGGGKKQIIDGLLSSGDVGYFDENGLLYISGRDDEMIVSGGENVFPAEVEDL 479
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
I+GHPDVVEA AIGVDDKE+G RLRAFVVKK GADLDEDT+K YVRDHLARYKVPREVIF
Sbjct 480 ITGHPDVVEATAIGVDDKEWGHRLRAFVVKKDGADLDEDTVKHYVRDHLARYKVPREVIF 539
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 540 LDELPRNPTGKILKRELREM 559
>gi|342859259|ref|ZP_08715913.1| acyl-CoA synthetase [Mycobacterium colombiense CECT 3035]
gi|342133500|gb|EGT86703.1| acyl-CoA synthetase [Mycobacterium colombiense CECT 3035]
Length=559
Score = 930 bits (2404), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 456/560 (82%), Positives = 503/560 (90%), Gaps = 4/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQA +K+Q QYV RG+AELHY+RKI ESGA +EPP NYAA+AADI KW
Sbjct 1 MPNLLGLPGQAAAKVQ----QYVERGSAELHYVRKIFESGAFRIEPPQNYAAMAADIYKW 56
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P+RAA IDEEG ++ ELDEA HAVA+GLL KG++ GDG+AILARN
Sbjct 57 GEFGMLPSLNARRHPDRAACIDEEGEFSYRELDEAGHAVAHGLLEKGIKGGDGIAILARN 116
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
RWF++ANYGAARVGARIILLNSEFSGPQIKEVS+REGAK+IIYDDEYTKAVS A+P LG
Sbjct 117 TRWFLVANYGAARVGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYTKAVSKAEPELG 176
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALG NPD D+PSGS+DETLAELI SS PAPKA++ ASIIILTSGTTGTPKGANR+
Sbjct 177 KLRALGTNPDADEPSGSTDETLAELIERSSKDPAPKAAKHASIIILTSGTTGTPKGANRS 236
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKAGEVT LP+PMFHALGY+H +AMFLGSTLVLRR+FKP LVL
Sbjct 237 TPPTLAPVGGILSHVPFKAGEVTSLPAPMFHALGYLHGTIAMFLGSTLVLRRKFKPPLVL 296
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHK T+MVVVPVMLSRIL+ +EK + KPDLSSLKIVFVSGS LGA+LA RAL DLG
Sbjct 297 EDIEKHKVTAMVVVPVMLSRILEAVEKMDRKPDLSSLKIVFVSGSALGADLAERALKDLG 356
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIA PK L++N STVGPVVKGV VKI D+NG E+PQG VGRIFVG
Sbjct 357 PVIYNMYGSTEIAFATIAEPKHLEYNSSTVGPVVKGVRVKIYDDNGKELPQGEVGRIFVG 416
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGG KQIIDGLLSSGDVGYFDE GLLY+SGRDDEMIVSGGENVFPAEVEDL
Sbjct 417 NAFPFEGYTGGGKKQIIDGLLSSGDVGYFDENGLLYISGRDDEMIVSGGENVFPAEVEDL 476
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
I+GHPDVVEA AIGV+DKE+G RLRAFVVKK GADLDEDT+K YVRDHLARYKVPREV+F
Sbjct 477 ITGHPDVVEATAIGVEDKEWGHRLRAFVVKKDGADLDEDTVKHYVRDHLARYKVPREVVF 536
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 537 LDELPRNPTGKILKRELREM 556
>gi|183980556|ref|YP_001848847.1| fatty-acid-CoA ligase FadD2 [Mycobacterium marinum M]
gi|183173882|gb|ACC38992.1| fatty-acid-CoA ligase FadD2 [Mycobacterium marinum M]
Length=557
Score = 929 bits (2402), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 469/560 (84%), Positives = 510/560 (92%), Gaps = 6/560 (1%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL+DLPG V+K+Q QYV RG AELHY+RKIIESGA LE PLNYAA+A +I KW
Sbjct 1 MPNLSDLPG--VAKIQ----QYVDRGAAELHYVRKIIESGAFRLESPLNYAAMATEIAKW 54
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P+RAA IDEEG T+ +LDEAAHAVAN LLAKGV AGDGVAILARN
Sbjct 55 GEFGMLPSFNARRHPHRAACIDEEGEFTYQQLDEAAHAVANALLAKGVSAGDGVAILARN 114
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYGAAR GARIILLNSEFSGPQIKEVS+REGAK+IIYDDEYT AVS A+PPLG
Sbjct 115 HRWFLIANYGAARAGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYTGAVSKAEPPLG 174
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPD ++ SGS+DETLAELIA SSTAPAPKA + ASIIILTSGTTGTPKGANR+
Sbjct 175 KLRALGVNPDSEEDSGSTDETLAELIARSSTAPAPKAGKHASIIILTSGTTGTPKGANRS 234
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKA EVT LP+PMFHALGY+HA +AMFLGSTLVLRR+FKP LVL
Sbjct 235 TPPTLAPVGGILSHVPFKANEVTSLPAPMFHALGYLHATIAMFLGSTLVLRRKFKPQLVL 294
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHK T+MVVVPVMLSR+LD +EK + KPDLSSLKIVFVSGSQLGAELA+RAL DLG
Sbjct 295 EDIEKHKVTAMVVVPVMLSRLLDAVEKIDKKPDLSSLKIVFVSGSQLGAELASRALKDLG 354
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGP+DLQ N +TVGPVVKGV VKILD+NGNEV QG VGRIFVG
Sbjct 355 PVIYNMYGSTEIAFATIAGPEDLQRNAATVGPVVKGVKVKILDDNGNEVSQGQVGRIFVG 414
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGG KQIIDGL+SSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 415 NAFPFEGYTGGGHKQIIDGLMSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDL 474
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA A+GVDDKE+GARLRAFVVKKP DLDE+T+K YVRDHLARYKVPREVIF
Sbjct 475 ISGHPDVVEATALGVDDKEWGARLRAFVVKKPDTDLDEETVKHYVRDHLARYKVPREVIF 534
Query 541 LDELPRNPTGKVLKRELRKL 560
L+ELPRNPTGK+LKRELR++
Sbjct 535 LEELPRNPTGKILKRELREM 554
>gi|118616906|ref|YP_905238.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99]
gi|118569016|gb|ABL03767.1| fatty-acid-CoA ligase FadD2 [Mycobacterium ulcerans Agy99]
Length=557
Score = 924 bits (2389), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 467/560 (84%), Positives = 508/560 (91%), Gaps = 6/560 (1%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL+DLPG V+K+Q QYV RG AELHY+RKIIESGA LE PLNYAA+A +I KW
Sbjct 1 MPNLSDLPG--VAKIQ----QYVDRGAAELHYVRKIIESGAFRLESPLNYAAMATEIAKW 54
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P+RAA IDEEG T+ +LDEA HAVAN LLAKGV AGDGVAILARN
Sbjct 55 GEFGMLPSFNARRHPHRAACIDEEGEFTYQQLDEAGHAVANALLAKGVSAGDGVAILARN 114
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYGAAR GARIILLNSEFSGPQIKEVS+REGAK+IIYDDEYT AVS A+PPLG
Sbjct 115 HRWFLIANYGAARAGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYTGAVSKAEPPLG 174
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPD ++ SGS+DETLAELIA SSTAPAPKA + ASIIILTSGTTGTPKGANR+
Sbjct 175 KLRALGVNPDSEEDSGSTDETLAELIARSSTAPAPKAGKHASIIILTSGTTGTPKGANRS 234
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKA EVT LP+PMFHALGY+HA +AMFLGSTLVLRR+FKP LVL
Sbjct 235 TPPTLAPVGGILSHVPFKANEVTSLPAPMFHALGYLHATIAMFLGSTLVLRRKFKPQLVL 294
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEKHK T+MVVVPVMLSR+LD +EK + KPDLSSLKIVFVSGSQLGAELA+RAL DLG
Sbjct 295 EDIEKHKVTAMVVVPVMLSRLLDAVEKIDKKPDLSSLKIVFVSGSQLGAELASRALKDLG 354
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGP+DLQ N +TVGPVVKGV VKILD+NGNEV QG VGRIFVG
Sbjct 355 PVIYNMYGSTEIAFATIAGPEDLQRNAATVGPVVKGVKVKILDDNGNEVSQGQVGRIFVG 414
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGG KQIIDGL+SSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVE L
Sbjct 415 NAFPFEGYTGGGHKQIIDGLMSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEAL 474
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA A+GVDDKE+GARLRAFVVKKP DLDE+T+K YVRDHLARYKVPREVIF
Sbjct 475 ISGHPDVVEATALGVDDKEWGARLRAFVVKKPDTDLDEETVKHYVRDHLARYKVPREVIF 534
Query 541 LDELPRNPTGKVLKRELRKL 560
L+ELPRNPTGK+LKRELR++
Sbjct 535 LEELPRNPTGKILKRELREM 554
>gi|296167546|ref|ZP_06849898.1| acyl-CoA synthetase [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295897168|gb|EFG76777.1| acyl-CoA synthetase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=559
Score = 906 bits (2342), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 457/560 (82%), Positives = 503/560 (90%), Gaps = 4/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MPNL LPGQAV+K+Q QY+ RG+AELHY+RKI E+GA LEPP NYAA+A DI KW
Sbjct 1 MPNLIGLPGQAVAKVQ----QYLERGSAELHYVRKIFEAGAFRLEPPQNYAAMANDIYKW 56
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GMLPS NARR P+RAA IDEEG TF++LDEAAHAVANGL+ GV+ GDGVAILARN
Sbjct 57 GEFGMLPSLNARRHPDRAACIDEEGEFTFAQLDEAAHAVANGLIEMGVKGGDGVAILARN 116
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
RWF+IANYGAARVGARIILLNSEFSGPQIKEVS+REGAK+IIYDDEYTKAVS A+P LG
Sbjct 117 TRWFLIANYGAARVGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYTKAVSKAEPELG 176
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
LRALG NPD D+PSGS DETLA+LI SS PAPKAS+ ASIIILTSGTTGTPKGANR+
Sbjct 177 FLRALGTNPDADEPSGSKDETLADLIERSSKEPAPKASKHASIIILTSGTTGTPKGANRS 236
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAP+GGILSHVPFKA EVT LP+PMFHALGY+H +AMFLGSTLVLRR+FKP LVL
Sbjct 237 TPPTLAPVGGILSHVPFKANEVTSLPAPMFHALGYLHGTIAMFLGSTLVLRRKFKPPLVL 296
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
EDIEK+K T+MVVVPVMLSRILD +EK + KPDLSSLKIVF+SGSQLGAELA+RAL DLG
Sbjct 297 EDIEKYKVTAMVVVPVMLSRILDAVEKMDKKPDLSSLKIVFISGSQLGAELASRALKDLG 356
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTE+AFATIAGP DL+ N +TVGPVVKGV VKILD+NG E PQG VGRIFVG
Sbjct 357 PVIYNMYGSTEIAFATIAGPHDLEKNAATVGPVVKGVKVKILDDNGKEKPQGEVGRIFVG 416
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
NAFPFEGYTGGG KQIIDGL+SSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 417 NAFPFEGYTGGGHKQIIDGLMSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDL 476
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHP+VVEA AIGV+DKE+G RLRAFVVKK G+D+DEDTIK YVRDHLARYKVPREV+F
Sbjct 477 ISGHPEVVEATAIGVEDKEWGHRLRAFVVKKDGSDVDEDTIKHYVRDHLARYKVPREVVF 536
Query 541 LDELPRNPTGKVLKRELRKL 560
L+ELPRNPTGK+LKRELR++
Sbjct 537 LEELPRNPTGKILKRELREM 556
>gi|333988898|ref|YP_004521512.1| fatty-acid-CoA ligase [Mycobacterium sp. JDM601]
gi|333484866|gb|AEF34258.1| fatty-acid-CoA ligase FadD2 [Mycobacterium sp. JDM601]
Length=556
Score = 898 bits (2321), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 448/560 (80%), Positives = 507/560 (91%), Gaps = 4/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
M LTDLP QAV+ L G+Y+ RG+AELHYLRK+++SGA+ LE P A+ AD +W
Sbjct 1 MAKLTDLPSQAVNTL----GRYLERGSAELHYLRKVLQSGALRLESPGIIASAIADGARW 56
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE+GM+P+ NARR PN AVID++G++TF ELD+AA+AVANGL+A GVR GDGVAILARN
Sbjct 57 GELGMIPALNARRNPNGLAVIDDDGSITFKELDDAANAVANGLVAMGVRGGDGVAILARN 116
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+IANYG ARVGAR+ILLNSEFSGPQIK+VS+REGAK+IIYDDEYT+AVS A PPLG
Sbjct 117 HRWFLIANYGCARVGARLILLNSEFSGPQIKDVSEREGAKLIIYDDEYTEAVSQADPPLG 176
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLRALGVNPD D+PSGS+DETLA+LIA SS A APK ++ ASIIILTSGTTGTPKGANR+
Sbjct 177 KLRALGVNPDSDQPSGSADETLAQLIARSSKARAPKVTKHASIIILTSGTTGTPKGANRS 236
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
TPPTLAPIGGILSHVPF+AGEVT LPSPMFHALGY+H LAMF GSTLVLRRRFKPA VL
Sbjct 237 TPPTLAPIGGILSHVPFRAGEVTSLPSPMFHALGYLHGTLAMFFGSTLVLRRRFKPATVL 296
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
ED+EKHK T +VVVPVMLSRILDQLEKT PKPDLS+L+IVFVSGSQLGAELATRA+ DLG
Sbjct 297 EDLEKHKVTGIVVVPVMLSRILDQLEKTSPKPDLSNLRIVFVSGSQLGAELATRAMKDLG 356
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYNMYGSTEVAFATIA P DLQ+NP+TVG VVKGV V+ILD+NG+++PQG VGRIFVG
Sbjct 357 PVIYNMYGSTEVAFATIADPGDLQYNPATVGQVVKGVKVRILDDNGHQLPQGEVGRIFVG 416
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
N FPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 417 NFFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 476
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHP+V+EA A+GV+DKE+GARLRAFVV+K G+ +DEDTIK YV++HLARYKVPREV+F
Sbjct 477 ISGHPEVIEATALGVEDKEWGARLRAFVVRKEGSSVDEDTIKVYVKEHLARYKVPREVVF 536
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR+L
Sbjct 537 LDELPRNPTGKILKRELREL 556
>gi|240168488|ref|ZP_04747147.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478]
Length=550
Score = 897 bits (2318), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 459/542 (85%), Positives = 501/542 (93%), Gaps = 0/542 (0%)
Query 19 IGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRA 78
I QYV RGT+ELHY+RKI+ESGA LE PLNYAA+A +I KWGE GMLPS NARR P+RA
Sbjct 7 IQQYVDRGTSELHYVRKIVESGAFRLESPLNYAAMANEIVKWGEFGMLPSLNARRHPDRA 66
Query 79 AVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARI 138
A IDE+G T+ ELD+AAHA+AN LLAKGVRAGDGVA+LARNHRWF+IANYGAARVGARI
Sbjct 67 ACIDEDGEFTYKELDDAAHALANALLAKGVRAGDGVALLARNHRWFLIANYGAARVGARI 126
Query 139 ILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSS 198
ILLNSEFSGPQIKEVS+REGAK+IIYDDEYTKAVS A+PPLGKLRALG NPD D+PSGS+
Sbjct 127 ILLNSEFSGPQIKEVSEREGAKLIIYDDEYTKAVSKAEPPLGKLRALGTNPDKDEPSGST 186
Query 199 DETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFK 258
DETLA+LIA SSTAPAPKA + ASIIILTSGTTGTPKGANR+TPPTLAP+GGILSHVPFK
Sbjct 187 DETLADLIARSSTAPAPKAGKHASIIILTSGTTGTPKGANRSTPPTLAPVGGILSHVPFK 246
Query 259 AGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVML 318
A EVT LP+PMFHALGY+HA +AMFLGSTLVLRR+FKP LVL+DIEKHK T+MVVVPVML
Sbjct 247 ANEVTSLPAPMFHALGYLHATIAMFLGSTLVLRRKFKPPLVLQDIEKHKVTAMVVVPVML 306
Query 319 SRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIA 378
SRILD +EK KPDLSSLKIVFVSGSQLGAELA+RAL DLGPVIYNMYGSTE+AFATIA
Sbjct 307 SRILDAIEKMHKKPDLSSLKIVFVSGSQLGAELASRALKDLGPVIYNMYGSTEIAFATIA 366
Query 379 GPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIID 438
GPKDL+ NP+TVGPVVKGV VKILDENG E+PQG VGRIFVGNAFPFEGYTGGG KQIID
Sbjct 367 GPKDLERNPATVGPVVKGVKVKILDENGKELPQGEVGRIFVGNAFPFEGYTGGGHKQIID 426
Query 439 GLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDK 498
GL+SSGDVGYFDE LLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEA AIGV+DK
Sbjct 427 GLMSSGDVGYFDEHNLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEATAIGVEDK 486
Query 499 EFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558
E+GARLRAFVVKKP A++DEDTIK YVRDHLARYKVPREVIF+DELPRNPTGK+LKRELR
Sbjct 487 EWGARLRAFVVKKPDAEVDEDTIKHYVRDHLARYKVPREVIFIDELPRNPTGKILKRELR 546
Query 559 KL 560
++
Sbjct 547 EM 548
>gi|15828369|ref|NP_302632.1| acyl-CoA synthetase [Mycobacterium leprae TN]
gi|221230846|ref|YP_002504262.1| acyl-CoA synthetase [Mycobacterium leprae Br4923]
gi|13093799|emb|CAC32077.1| acyl-CoA synthase [Mycobacterium leprae]
gi|219933953|emb|CAR72645.1| acyl-CoA synthase [Mycobacterium leprae Br4923]
Length=548
Score = 895 bits (2312), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 448/540 (83%), Positives = 491/540 (91%), Gaps = 0/540 (0%)
Query 21 QYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAV 80
Y+ RG AE+HYLR I ESGA+G EPPL YAA+A +RKWG++ MLP+ ARR+P+RAA+
Sbjct 6 HYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSPHRAAL 65
Query 81 IDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIIL 140
IDEEGTLT+ ELD AAHA+ANGL+AKGVR GDG+AILARNHRWFVIANYG ARVGARIIL
Sbjct 66 IDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIIL 125
Query 141 LNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDE 200
LNSEFSGPQIKEVS+REGAKVIIYDDEYTK VS A+P LGKLRALGVNPD+++P GS+DE
Sbjct 126 LNSEFSGPQIKEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDE 185
Query 201 TLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAG 260
TLAELIA SS+APAPK +RASIIILTSGTTGTPKGANRNTP +LAP+GGILS VPF+A
Sbjct 186 TLAELIARSSSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGGILSKVPFRAH 245
Query 261 EVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSR 320
EVTLLP+PMFHALGY+HA LAMFLGSTLVLRRRFKPA VLEDIEKH+AT+MVVVPVMLSR
Sbjct 246 EVTLLPAPMFHALGYLHATLAMFLGSTLVLRRRFKPATVLEDIEKHQATAMVVVPVMLSR 305
Query 321 ILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGP 380
ILD LE E K DLSSL++VFVSGSQLGAELATRAL +LGPVIYNMYGSTE+AFATIAGP
Sbjct 306 ILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALEELGPVIYNMYGSTEIAFATIAGP 365
Query 381 KDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGL 440
KDLQ N +TVGPVVKGV VKILD++G EVP+G VGRIFVGNAFPFEGYTGGGGKQIIDGL
Sbjct 366 KDLQINSATVGPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQIIDGL 425
Query 441 LSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEF 500
LSSGDVGYFDE LLY+SGRDDEMIVSGGENVFPAEVEDLISGHP+VVEA AIGVDDKE+
Sbjct 426 LSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKEW 485
Query 501 GARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL 560
GARLRAFVVKK A +DED IK YVRDHLARYKVPREVIFL+ELPRNPTGKVLKRELR
Sbjct 486 GARLRAFVVKKQDATIDEDAIKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDF 545
>gi|120401422|ref|YP_951251.1| acyl-CoA synthetase [Mycobacterium vanbaalenii PYR-1]
gi|119954240|gb|ABM11245.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii
PYR-1]
Length=564
Score = 891 bits (2302), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 425/560 (76%), Positives = 503/560 (90%), Gaps = 0/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MP L+DLP QA +KLQ+++G Y+ RG+AELHY RK+ E+GA+ LEPP + AA AD+R+W
Sbjct 1 MPKLSDLPLQAAAKLQQTVGTYLERGSAELHYARKMFEAGALKLEPPQDIAAFVADMRRW 60
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GM+P+ NARR P+RAAVID+ G +TF ELD+AA+AVANGLLAKGV+ GDGVAILARN
Sbjct 61 GEFGMIPALNARRYPHRAAVIDDFGEMTFKELDDAANAVANGLLAKGVKGGDGVAILARN 120
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF+++ Y A +VGARIILLNSEFSGPQIKEVS+REGAK++IYDDEYT AV+ A+P LG
Sbjct 121 HRWFLVSVYAAGKVGARIILLNSEFSGPQIKEVSEREGAKLVIYDDEYTAAVAAAEPELG 180
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
KLR+LGVNPD ++PSGS+DETL ELIA +++ P PKA++ +SIIILTSGTTGTPKGANR+
Sbjct 181 KLRSLGVNPDKEEPSGSTDETLEELIARTTSNPPPKATKHSSIIILTSGTTGTPKGANRS 240
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
PP+LAPIGGILS VPFK+ VT LP+PMFHALG++HA +AM LG+TLVLRRRFKPA VL
Sbjct 241 APPSLAPIGGILSSVPFKSQAVTSLPAPMFHALGFLHATIAMMLGTTLVLRRRFKPATVL 300
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
DIEKH+AT++VVVPVMLSR+LD+L+KT PKPDLSSL+IVFVSGSQLGAELATRAL +LG
Sbjct 301 ADIEKHRATAIVVVPVMLSRMLDELDKTSPKPDLSSLRIVFVSGSQLGAELATRALKELG 360
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PV+YN+YGSTEVAFATIAGP+ L NP+TVGPVVKG+ V+ILD+NGN+VP+G VGRIFVG
Sbjct 361 PVVYNLYGSTEVAFATIAGPQHLSINPATVGPVVKGMKVRILDDNGNDVPRGQVGRIFVG 420
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
N FPF+GYTGGGGKQIIDGLLSSGDVGYFDE LLYVSGRDDEMIVSGGENVFPAE+EDL
Sbjct 421 NFFPFQGYTGGGGKQIIDGLLSSGDVGYFDENDLLYVSGRDDEMIVSGGENVFPAEIEDL 480
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
+SGHP+VVEA AIGV+DKE+GARLR FVVK GA +DED IK YVRD+LARYKVPREV+F
Sbjct 481 VSGHPEVVEATAIGVEDKEWGARLRCFVVKIEGAAVDEDAIKAYVRDNLARYKVPREVVF 540
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKR+LR++
Sbjct 541 LDELPRNPTGKILKRQLREM 560
>gi|145220945|ref|YP_001131623.1| acyl-CoA synthetase [Mycobacterium gilvum PYR-GCK]
gi|315442085|ref|YP_004074964.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium
sp. Spyr1]
gi|145213431|gb|ABP42835.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK]
gi|315260388|gb|ADT97129.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium
sp. Spyr1]
Length=569
Score = 880 bits (2274), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 425/564 (76%), Positives = 495/564 (88%), Gaps = 4/564 (0%)
Query 1 MPNLTDLPGQAVSK----LQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAAD 56
M L+DLP QA++ L KS+G+YV RG+AELHY RK+ ++GA+ LEPP + AA AD
Sbjct 1 MSKLSDLPAQALATVSQTLGKSVGKYVERGSAELHYARKMFQAGALKLEPPQDIAAFVAD 60
Query 57 IRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAI 116
+ +WGE GM+P+ NARR P+R AVID+ G TF ELDEA +AVANGLLAKGV+ GDGVAI
Sbjct 61 MVRWGEFGMIPALNARRHPHRTAVIDDFGEFTFGELDEAVNAVANGLLAKGVKGGDGVAI 120
Query 117 LARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQ 176
LARNHRWF+++ Y A +VGARIILLNSEFSGPQIKEVS REGAK++IYDDEYT AV A+
Sbjct 121 LARNHRWFLVSVYAAGKVGARIILLNSEFSGPQIKEVSHREGAKLVIYDDEYTAAVKAAE 180
Query 177 PPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKG 236
P LGKLR+LGVNPD D PSGS+DETL ELIA +S+ P PKA++ +SIIILTSGTTGTPKG
Sbjct 181 PELGKLRSLGVNPDKDAPSGSTDETLEELIARTSSTPPPKATKHSSIIILTSGTTGTPKG 240
Query 237 ANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKP 296
ANR+ PP+LAPIGGILS VPFK+ EVT LP+PMFHALG++HA +AM LGSTLVLRRRFKP
Sbjct 241 ANRSAPPSLAPIGGILSAVPFKSEEVTSLPAPMFHALGFLHATIAMMLGSTLVLRRRFKP 300
Query 297 ALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRAL 356
A VL DIEKH+AT++VVVPVMLSR+LD+L+KT PKPDLSSL+I+FVSGSQLGAELATRAL
Sbjct 301 ATVLADIEKHRATAIVVVPVMLSRMLDELDKTSPKPDLSSLRILFVSGSQLGAELATRAL 360
Query 357 GDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGR 416
DLGP++YN+YGSTEVAFATIAGP+ L NP+TVGPVVKG+ VKILD+NGNE+P+G +GR
Sbjct 361 KDLGPIVYNLYGSTEVAFATIAGPQHLSINPATVGPVVKGMRVKILDDNGNELPRGEIGR 420
Query 417 IFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAE 476
IFVGN FPFEGYTGGGGKQIIDGLLSSGDVGYFD+ LLYVSGRDDEMIVSGGENVFPAE
Sbjct 421 IFVGNFFPFEGYTGGGGKQIIDGLLSSGDVGYFDDNDLLYVSGRDDEMIVSGGENVFPAE 480
Query 477 VEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPR 536
+EDL+SGHP+VVEA A+GV+DKE+G RLR FVVK GA +DED IK YVRD+LARYKVPR
Sbjct 481 IEDLVSGHPEVVEATALGVEDKEWGHRLRCFVVKAEGATIDEDAIKAYVRDNLARYKVPR 540
Query 537 EVIFLDELPRNPTGKVLKRELRKL 560
EVIFLDELPRNPTGK+LKRELR++
Sbjct 541 EVIFLDELPRNPTGKILKRELREM 564
>gi|118473796|ref|YP_885010.1| acyl-CoA synthetase [Mycobacterium smegmatis str. MC2 155]
gi|118175083|gb|ABK75979.1| acyl-CoA synthase [Mycobacterium smegmatis str. MC2 155]
Length=548
Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 424/540 (79%), Positives = 477/540 (89%), Gaps = 0/540 (0%)
Query 21 QYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAV 80
+Y RG AELHY RK+ E+GA+ LEPP + AL ADIR WGE+GM+P+ NARR PNR AV
Sbjct 7 EYAERGVAELHYARKMFEAGALRLEPPQHMLALVADIRTWGEIGMIPALNARRHPNRVAV 66
Query 81 IDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIIL 140
ID+EG TF ELD AAHA+AN LLA+GVR GDGV ILARNHRWF+++ YGAARVGARII+
Sbjct 67 IDDEGEFTFGELDAAAHALANELLARGVRGGDGVGILARNHRWFLVSLYGAARVGARIIM 126
Query 141 LNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDE 200
LN+EFSGPQIKEV+ REGA+VIIYDDEYT AV+ A+ LGKLRALG NPD ++PSGS+DE
Sbjct 127 LNTEFSGPQIKEVAAREGARVIIYDDEYTAAVAQAETELGKLRALGTNPDKEEPSGSTDE 186
Query 201 TLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAG 260
TLAE+IA S PAPKASR ASIIILTSGTTGTPKGANR PP+LAPIGG+LSHVPFKAG
Sbjct 187 TLAEVIARSGKRPAPKASRHASIIILTSGTTGTPKGANRAAPPSLAPIGGVLSHVPFKAG 246
Query 261 EVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSR 320
EVT LP+PMFHALG++HA +AM LGSTLVLRRRFKPA VLEDIEKHK T+ VVVPVMLSR
Sbjct 247 EVTALPAPMFHALGFLHATIAMMLGSTLVLRRRFKPATVLEDIEKHKVTAAVVVPVMLSR 306
Query 321 ILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGP 380
+LD LEK KPDLSSL+I+FVSGSQLGAELATRAL +LGPVIYN+YGSTE+AFATIA P
Sbjct 307 MLDHLEKMPQKPDLSSLRIMFVSGSQLGAELATRALKELGPVIYNLYGSTEIAFATIARP 366
Query 381 KDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGL 440
+DL NP+TVGPVVKG+TVKILD+NG E+PQG VGRIFV N FPF+GYTGGGGKQIIDG+
Sbjct 367 QDLSRNPATVGPVVKGITVKILDDNGKELPQGEVGRIFVRNTFPFKGYTGGGGKQIIDGM 426
Query 441 LSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEF 500
+SSGDVGYFDE GLLY+SGRDDEMIVSGGENVFPAEVEDLISGHP+V+EA AIGVDDKE+
Sbjct 427 MSSGDVGYFDEHGLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVIEATAIGVDDKEW 486
Query 501 GARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL 560
GARLRAFVVK G+ L ED +K YVRDHLARYKVPREVIFLDELPRNPTGK+LKRELR +
Sbjct 487 GARLRAFVVKAAGSSLTEDDVKAYVRDHLARYKVPREVIFLDELPRNPTGKILKRELRNI 546
>gi|108797341|ref|YP_637538.1| acyl-CoA synthetase [Mycobacterium sp. MCS]
gi|119866426|ref|YP_936378.1| acyl-CoA synthetase [Mycobacterium sp. KMS]
gi|108767760|gb|ABG06482.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS]
gi|119692515|gb|ABL89588.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS]
Length=577
Score = 854 bits (2207), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 421/560 (76%), Positives = 491/560 (88%), Gaps = 4/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MP LT+LP Q +K + Y+ RG+AELHY RK+ E+GA+ LEPP N AA AD+R+W
Sbjct 1 MPKLTELPSQVAAKAK----LYLDRGSAELHYARKMFEAGALQLEPPQNMAAFVADMRRW 56
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GM+P+ NARR P+R AVID+EG +T++ELDEAAHAVA+ LLAKG++ GDGVA+LARN
Sbjct 57 GEFGMIPALNARRTPDRNAVIDDEGEMTYAELDEAAHAVAHALLAKGIKGGDGVAVLARN 116
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF++A YGAAR GARIILLNSEFSGPQIKEVS+REGAK+II+DDEY+KAVS A+P LG
Sbjct 117 HRWFLVAVYGAARTGARIILLNSEFSGPQIKEVSEREGAKLIIHDDEYSKAVSQAKPELG 176
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
LRALG NPD+ +PS S +TLA+++A APAPK ++ +S+IILTSGTTGTPKGANR
Sbjct 177 YLRALGTNPDNSEPSESDAQTLADIVAGGDKAPAPKVTKHSSVIILTSGTTGTPKGANRK 236
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
P +LAPIGGILSHVPFK+GEVTLLP+PMFHALGY+HA + M LGSTLVLRRRFKPA VL
Sbjct 237 PPMSLAPIGGILSHVPFKSGEVTLLPAPMFHALGYLHATIGMMLGSTLVLRRRFKPATVL 296
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
D+EK++AT+MVVVPVMLSR+LD +EKT+ KPDLSSL+IVFVSGSQLGAELATRA+ D+G
Sbjct 297 ADVEKYRATAMVVVPVMLSRLLDHIEKTDTKPDLSSLRIVFVSGSQLGAELATRAMKDIG 356
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYN+YGSTE+AFATIA P+DLQ NP+TVGPVVKGV VK+ DENG EVP+G VGRIFVG
Sbjct 357 PVIYNLYGSTEIAFATIARPEDLQKNPATVGPVVKGVRVKLFDENGKEVPRGEVGRIFVG 416
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
FPFEGYTGGG KQIIDGL+SSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 417 TTFPFEGYTGGGHKQIIDGLMSSGDVGYFDEDGLLYVSGRDDEMIVSGGENVFPAEVEDL 476
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA A+GV+DKE+G RLRAFVVK GA +DED IK YV++HLARYKVPREV+F
Sbjct 477 ISGHPDVVEATALGVEDKEWGHRLRAFVVKAEGASVDEDAIKGYVKEHLARYKVPREVVF 536
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 537 LDELPRNPTGKILKRELREM 556
>gi|126432963|ref|YP_001068654.1| acyl-CoA synthetase [Mycobacterium sp. JLS]
gi|126232763|gb|ABN96163.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS]
Length=574
Score = 852 bits (2202), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 420/560 (75%), Positives = 490/560 (88%), Gaps = 4/560 (0%)
Query 1 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKW 60
MP LT+LP Q +K + Y+ RG+AELHY RK+ E+GA+ LEPP N AA AD+R+W
Sbjct 1 MPKLTELPSQVAAKAK----LYLDRGSAELHYARKMFEAGALQLEPPQNMAAFVADMRRW 56
Query 61 GEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARN 120
GE GM+P+ NARR P+R AVID+EG +T++ELDEAAHAVA+ LLAKG++ GDGVA+LARN
Sbjct 57 GEFGMIPALNARRTPDRNAVIDDEGEMTYAELDEAAHAVAHALLAKGIKGGDGVAVLARN 116
Query 121 HRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLG 180
HRWF++A YGAAR GARIILLNSEFSGPQIKEVS+REGAK+II+DDEY+KAVS A+P LG
Sbjct 117 HRWFLVAVYGAARTGARIILLNSEFSGPQIKEVSEREGAKLIIHDDEYSKAVSQAKPELG 176
Query 181 KLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRN 240
LRALG NPD+ +PS S +TLA+++A PAPK ++ +S+IILTSGTTGTPKGANR
Sbjct 177 YLRALGTNPDNSEPSESDAQTLADIVAGGDKTPAPKVTKHSSVIILTSGTTGTPKGANRK 236
Query 241 TPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVL 300
P +LAPIGGILSHVPFK+GEVTLLP+PMFHALGY+HA + M LGSTLVLRRRFKPA VL
Sbjct 237 PPLSLAPIGGILSHVPFKSGEVTLLPAPMFHALGYLHATIGMMLGSTLVLRRRFKPATVL 296
Query 301 EDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLG 360
D+EK++AT+MVVVPVMLSR+LD +EKT+ KPDLSSL+IVFVSGSQLGAELATRA+ D+G
Sbjct 297 ADVEKYRATAMVVVPVMLSRLLDHIEKTDTKPDLSSLRIVFVSGSQLGAELATRAMKDIG 356
Query 361 PVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVG 420
PVIYN+YGSTE+AFATIA P+DLQ NP+TVGPVVKGV VK+ DENG EVP+G VGRIFVG
Sbjct 357 PVIYNLYGSTEIAFATIARPEDLQKNPATVGPVVKGVRVKLFDENGKEVPRGEVGRIFVG 416
Query 421 NAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDL 480
FPFEGYTGGG KQIIDGL+SSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDL
Sbjct 417 TTFPFEGYTGGGHKQIIDGLMSSGDVGYFDEDGLLYVSGRDDEMIVSGGENVFPAEVEDL 476
Query 481 ISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIF 540
ISGHPDVVEA A+GV+DKE+G RLRAFVVK GA +DED IK YV++HLARYKVPREV+F
Sbjct 477 ISGHPDVVEATALGVEDKEWGHRLRAFVVKAEGASVDEDAIKGYVKEHLARYKVPREVVF 536
Query 541 LDELPRNPTGKVLKRELRKL 560
LDELPRNPTGK+LKRELR++
Sbjct 537 LDELPRNPTGKILKRELREM 556
>gi|169631417|ref|YP_001705066.1| acyl-CoA synthetase [Mycobacterium abscessus ATCC 19977]
gi|169243384|emb|CAM64412.1| Probable fatty-acid-CoA synthetase FadD [Mycobacterium abscessus]
Length=556
Score = 746 bits (1926), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 362/548 (67%), Positives = 450/548 (83%), Gaps = 4/548 (0%)
Query 13 SKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNAR 72
SKLQ RG AELHYLRK+IE+G + L+PP A L D ++GE+G +P+ A
Sbjct 11 SKLQ----TLAKRGGAELHYLRKVIEAGMLKLDPPNVLAGLVRDFYRFGEIGAVPAFGAH 66
Query 73 RAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAA 132
R+P+R A+ID+EG++T++EL++A +A+A+GL G++ GDGVAILARNHRWF+IANY A
Sbjct 67 RSPSRTAIIDDEGSITYAELNDAVNALAHGLNRLGIKGGDGVAILARNHRWFIIANYAAH 126
Query 133 RVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDD 192
R GAR+ILLN++FSGPQ KEV++REGA+V+IYD EY + + P LG++ AL NPD+
Sbjct 127 RAGARVILLNTDFSGPQTKEVAEREGARVLIYDAEYAEFLDGYSPELGRIMALPTNPDNP 186
Query 193 KPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGIL 252
S+DET+A +I +ST+PAP+ S+ +S++ILTSGTTGTPKGA R TLAP+GG+
Sbjct 187 DQPASTDETIASVIKRNSTSPAPRPSKYSSLVILTSGTTGTPKGAPRKLALTLAPVGGMF 246
Query 253 SHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMV 312
SHVPF++GEVT +P+PMFHALGY+H +LA+ LG TL+LRR+FKP VL D+EK K T++V
Sbjct 247 SHVPFRSGEVTSVPAPMFHALGYLHQSLALTLGCTLILRRKFKPENVLADVEKFKVTAIV 306
Query 313 VVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEV 372
VVPVML+R+L+ L++ KPDLSSL+IVFVSGSQLG ELA+RA+ LGPVIYN+YGSTEV
Sbjct 307 VVPVMLNRLLNALDELSVKPDLSSLRIVFVSGSQLGGELASRAMDTLGPVIYNLYGSTEV 366
Query 373 AFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGG 432
AFATIA P+DL NPSTVGPVVKG TVKILD+ G V QG VGRIFV NA PF+GYTGGG
Sbjct 367 AFATIARPQDLAINPSTVGPVVKGATVKILDDEGKPVSQGTVGRIFVSNAIPFDGYTGGG 426
Query 433 GKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAA 492
KQIIDGL+SSGDVGYFDE GLLYVSGRDDEMIVSGGENVFPAEVEDLISGHP+V+EA A
Sbjct 427 HKQIIDGLMSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPEVIEATA 486
Query 493 IGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKV 552
+GVDD E+GARLRAFVV+ P + +D D I+ YVRD+LARYKVPR+V+FLD LPRNP+GK+
Sbjct 487 LGVDDPEWGARLRAFVVRHPDSTVDADGIRAYVRDNLARYKVPRDVVFLDVLPRNPSGKI 546
Query 553 LKRELRKL 560
LKRELR+L
Sbjct 547 LKRELREL 554
>gi|284041810|ref|YP_003392150.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM
14684]
gi|283946031|gb|ADB48775.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM
14684]
Length=542
Score = 570 bits (1468), Expect = 3e-160, Method: Compositional matrix adjust.
Identities = 298/534 (56%), Positives = 384/534 (72%), Gaps = 7/534 (1%)
Query 25 RGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEE 84
R E+ Y+ + +G + EPP ++A D+ ++G VG LP+ ARR +R +IDE
Sbjct 10 RARNEVTYVTACVRAGVVRPEPPRSFARNLRDVARYGFVGALPALAARRRGDRPGLIDER 69
Query 85 GTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSE 144
GTLTFS+LD A+A+ANG A G+RAGDGVAILARNHR FV A AAR GAR++LLN++
Sbjct 70 GTLTFSQLDRRANALANGWRAHGLRAGDGVAILARNHRGFVEATTAAARCGARVVLLNTD 129
Query 145 FSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAE 204
F+GPQI++V+ REG ++++DDEY + +P LG+ RA DD ++ TL
Sbjct 130 FAGPQIRDVAAREGVDLLVHDDEYATFLDGIEPRLGRWRAW----TDD--GAAAPGTLEA 183
Query 205 LIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTL 264
LIA S AP P+ + A +++LTSGTTGTPKGA R P +L P+G +LS VPF+AGE T+
Sbjct 184 LIARGSPAPPPRPASEAKLVVLTSGTTGTPKGAPRTVPKSLQPLGALLSVVPFRAGETTV 243
Query 265 LPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQ 324
+ +P+FH+LG++ LA+ LGSTLVLRRRF PA++L+D+ +H+A+++VVVPVML R+L
Sbjct 244 VAAPLFHSLGFVQGQLALALGSTLVLRRRFDPAVLLDDLARHRASAVVVVPVMLRRVLAL 303
Query 325 LEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQ 384
+ DLS+L+IVFV+GSQLGAEL R GP +YN+YGSTEVA+ATIA P DL
Sbjct 304 GDDAVAGRDLSALRIVFVAGSQLGAELCERTTAAFGPRVYNLYGSTEVAYATIATPADLA 363
Query 385 FNPSTVGPVVKGVTVKILDENGNEVP-QGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSS 443
P VG G V++ D+ G V G GRIFVGN F FEGYTGGG K+ IDGL+SS
Sbjct 364 VEPGCVGRPPPGAVVRLYDDAGAPVTGPGHSGRIFVGNGFEFEGYTGGGSKETIDGLMSS 423
Query 444 GDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGAR 503
GDVG+FD G L+V GRDDEMIVSGGENVFPAEVE+L+ HP V EAA I V+D+ +G R
Sbjct 424 GDVGHFDAAGRLFVDGRDDEMIVSGGENVFPAEVEELLHRHPAVEEAALIAVEDEAWGQR 483
Query 504 LRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
LRAFVV + G L ED +K +VR++LARYKVPRE +FLD LPRNPTGKVLKREL
Sbjct 484 LRAFVVVRAGEQLGEDAVKAFVRENLARYKVPREAVFLDALPRNPTGKVLKREL 537
>gi|54025764|ref|YP_120006.1| acyl-CoA synthetase [Nocardia farcinica IFM 10152]
gi|54017272|dbj|BAD58642.1| putative acyl-CoA synthetase [Nocardia farcinica IFM 10152]
Length=541
Score = 505 bits (1300), Expect = 1e-140, Method: Compositional matrix adjust.
Identities = 263/516 (51%), Positives = 349/516 (68%), Gaps = 8/516 (1%)
Query 45 EPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLL 104
E P A + + + G +G L A R +R AV+DE G ++F ELDE A+AN
Sbjct 33 ERPDRLAGMGLAVVRSGLLGGLVGVAAVRYRDRTAVLDERGRVSFRELDERTTALANAWR 92
Query 105 AKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIY 164
A+G+R G+GVA+L RNHR F A + AA+ GARIIL+N++F Q++EV REGA ++++
Sbjct 93 ARGLRDGEGVAVLTRNHRGFHYAVFAAAKCGARIILVNTDFGAGQLREVLAREGADLVVH 152
Query 165 DDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASII 224
D+E+T + +P G+ RA P D TL LIA + PA + A I+
Sbjct 153 DEEFTGLLGDLRPRRGRYRAWTDAPAVD--------TLDNLIAGGARTPARRPRTPARIV 204
Query 225 ILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFL 284
+LTSGTTGTPKGA R P +L+P+GG+L+ VP + EVT P+P+FH LG+ HA LA+
Sbjct 205 LLTSGTTGTPKGAPRREPTSLSPLGGLLARVPLRVREVTECPAPLFHTLGFAHAVLALGF 264
Query 285 GSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSG 344
G+TLV+RR+F P VL+ + +H+A+++VVVPVML R++D +LS L++VFV+G
Sbjct 265 GTTLVIRRKFDPEAVLDSLVRHRASTLVVVPVMLRRLVDADPHARAHRELSRLRVVFVAG 324
Query 345 SQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDE 404
SQLGA L RA GPV+YN+YGSTE A+ATIA P DL P VG V G V ILD
Sbjct 325 SQLGAPLCLRATEAFGPVLYNVYGSTEAAYATIATPADLAEAPGCVGRPVPGAVVAILDA 384
Query 405 NGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEM 464
E+P G GRIFVGN + FEGYTGGG K + GL+++GD+G+ D G L+V GR+D+M
Sbjct 385 ADRELPAGHTGRIFVGNDYQFEGYTGGGDKPRVRGLMATGDLGHVDAAGRLFVDGREDDM 444
Query 465 IVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQY 524
IVSGGENVFP EVEDL++ HP V EA+A GVDD E+G RLR VV +PG L + ++ +
Sbjct 445 IVSGGENVFPGEVEDLLAAHPAVAEASAFGVDDDEYGQRLRVAVVLRPGHALTAEQVRDH 504
Query 525 VRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL 560
VR HLARYKVPR+V+FL ELPRNP+GKVL R LR+L
Sbjct 505 VRTHLARYKVPRDVLFLPELPRNPSGKVLVRVLREL 540
>gi|284045146|ref|YP_003395486.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM
14684]
gi|283949367|gb|ADB52111.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM
14684]
Length=532
Score = 475 bits (1223), Expect = 7e-132, Method: Compositional matrix adjust.
Identities = 261/534 (49%), Positives = 346/534 (65%), Gaps = 9/534 (1%)
Query 27 TAELHYLRKIIESGAIGLEPPLNYAALAADIRKWG--EVGMLPSHNARRAPNRAAVIDEE 84
T + + ++ SG IG P A + +++WG G AR+ P++ A+IDE
Sbjct 6 THQAFVAKTLVGSGLIGPTRPDRLAKVGLALKRWGTTSAGAFAVTAARK-PDQPAIIDEL 64
Query 85 GTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSE 144
GTL++ EL A+A+A+ +G+R GD +A++ RNHR FV +R+GA II LN+
Sbjct 65 GTLSYGELHRRANALASSFANEGIRPGDAIAVMCRNHRGFVDVTVATSRLGANIIYLNTA 124
Query 145 FSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAE 204
F+GPQ+ EV +RE A I+YD+E+ V P+ R V D + S + D + +
Sbjct 125 FAGPQLAEVIERERAAAIVYDEEFANIVE----PVRAGRKSYVAWHDGE-SANGDRLIED 179
Query 205 LIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTL 264
LIA A P A+ +IILTSGTTG PKGA R+ A +LS +P KA E T+
Sbjct 180 LIAEGDAAGVPPAAEPGRVIILTSGTTGAPKGARRSAAGLGAAAA-LLSKMPLKARETTM 238
Query 265 LPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQ 324
+ +P+FH G H L + L ST+VLRRRF P L I +H+A+ +VVVPVML R+L+
Sbjct 239 IAAPIFHTWGLAHFTLGVPLASTIVLRRRFDPEGTLRAIARHRASGLVVVPVMLQRMLEL 298
Query 325 LEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQ 384
+ K D SSL+++ SGS L L+TR + G V+YN YGSTEVA+ATIA P D++
Sbjct 299 PDDVFAKYDTSSLRVIAASGSALPGPLSTRVMDRFGDVLYNTYGSTEVAWATIATPADMR 358
Query 385 FNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSG 444
P T G G V++LDE+G EVP G GRIFVGN PFEGYTGGG K+IIDGL+SSG
Sbjct 359 AAPGTAGRPPVGTRVRLLDEDGREVPAGQTGRIFVGNELPFEGYTGGGNKEIIDGLMSSG 418
Query 445 DVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARL 504
DVG+FD G L+V GRDD+MI+SGGENVFP+EVEDL++GH V E A IG+ D+E+G RL
Sbjct 419 DVGHFDSGGRLFVDGRDDDMIISGGENVFPSEVEDLLAGHGAVREVAVIGIADEEWGQRL 478
Query 505 RAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558
+A VV P A ED +K YVR +LA +KVPREV+F++ELPRN TGKVLKRELR
Sbjct 479 KAVVVLNPEAASTEDELKAYVRANLAGFKVPREVVFVEELPRNATGKVLKRELR 532
>gi|333920077|ref|YP_004493658.1| AMP-dependent synthetase and ligase [Amycolicicoccus subflavus
DQS3-9A1]
gi|333482298|gb|AEF40858.1| AMP-dependent synthetase and ligase [Amycolicicoccus subflavus
DQS3-9A1]
Length=692
Score = 452 bits (1163), Expect = 8e-125, Method: Compositional matrix adjust.
Identities = 252/540 (47%), Positives = 334/540 (62%), Gaps = 15/540 (2%)
Query 25 RGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDE 83
R EL Y + G + P LA R WG +G + A R+ ++DE
Sbjct 158 RAIRELTYAGVLARRGIVRPMRPDTLFRLAWAARTWGLSLGTAVAAGAIRSGGAPLIVDE 217
Query 84 EGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNS 143
GT T++E+DE ++A+A+GL GV D V +LARNHR F+ A A+VGA ++LLN+
Sbjct 218 FGTQTYAEVDERSNAIASGLALHGVTESDTVGVLARNHRGFLEAATAVAKVGADVLLLNT 277
Query 144 EFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALG-VNPDDDKPSGSSDETL 202
EFSGPQ++EV+ RE +IYD E+ + P+ LR +PD D PS +S
Sbjct 278 EFSGPQLREVTTREAVSAVIYDTEFHAL--MGDSPMHMLRVFSDADPDGDAPSLAS---- 331
Query 203 AELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPP-----TLAPIGGILSHVPF 257
+ H P P +R + ILTSGTTGTPKGA R TL +L +P
Sbjct 332 FAVEYHGRRPPVP--NRSGKLTILTSGTTGTPKGATRGAVAAGGTLTLEAPAALLGRIPL 389
Query 258 KAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVM 317
+AG L +P FHA G + +A+ LG+++V+ RRF L +I++ K + + +PVM
Sbjct 390 RAGMRIGLAAPAFHAWGLANLVMALGLGASVVMLRRFSAEEWLAEIDRSKCEAFIAIPVM 449
Query 318 LSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATI 377
L RILD + K D SSL++V VSGS L +LATR + G +YN+YGSTEVA ATI
Sbjct 450 LQRILDLPKDVRDKYDTSSLEVVAVSGSALAGDLATRWMDSFGDNLYNLYGSTEVANATI 509
Query 378 AGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQII 437
A P+DL+ P T G +G TV++ D++G EV QG GRI+VGNA FEGYTGGG K+ I
Sbjct 510 ATPQDLRTAPGTAGRPTRGTTVRLFDQSGKEVRQGETGRIYVGNAHLFEGYTGGGDKERI 569
Query 438 DGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDD 497
GL+++GD+G FDE G L+V GRDDEMIVSGGENV+P EVED+I+ H V EAA +GVDD
Sbjct 570 GGLMATGDLGRFDEAGRLFVVGRDDEMIVSGGENVYPREVEDVIARHASVAEAACVGVDD 629
Query 498 KEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
+FG RLRAFVV + G L D +K VR LARYKVPR++ FLD LPRN GK++KR+L
Sbjct 630 DKFGQRLRAFVVLRDGETLSADEVKDLVRAQLARYKVPRDIEFLDALPRNAAGKIVKRQL 689
>gi|119716227|ref|YP_923192.1| AMP-dependent synthetase and ligase [Nocardioides sp. JS614]
gi|119536888|gb|ABL81505.1| AMP-dependent synthetase and ligase [Nocardioides sp. JS614]
Length=541
Score = 443 bits (1139), Expect = 5e-122, Method: Compositional matrix adjust.
Identities = 264/545 (49%), Positives = 350/545 (65%), Gaps = 14/545 (2%)
Query 15 LQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGE--VGMLPSHNAR 72
LQK+ A GT L+ + E+G I P+ A +A ++ WG G + A
Sbjct 6 LQKARAGATATGTT----LKVLGEAGVIRPRNPVALAKVAKALKDWGTGPAGGFTA-AAL 60
Query 73 RAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAA 132
P R A+IDE G+LTF+EL ++A+A GV GD VA++ RNHR FV A+ AA
Sbjct 61 LDPRRTAIIDELGSLTFAELQRRSNALARAFAELGVSEGDSVALMCRNHRGFVEASIAAA 120
Query 133 RVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDD 192
++GA I+ LN+ F+GPQ+ EV +RE ++++D+E+T+ LA+ +G ++ D
Sbjct 121 KLGADILYLNTAFAGPQLVEVLEREQPALVVHDEEFTRL--LAKADVGT--SVLAWTDSA 176
Query 193 KPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGIL 252
S+D TL LIA S A R I+ILTSGTTGTPKGA R+ A + +L
Sbjct 177 DSDDSADPTLESLIAGRSGADLEPTGRHGRIVILTSGTTGTPKGAPRSEAGIDAAVS-LL 235
Query 253 SHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMV 312
S +P + G T + +P+FH G+ H ALAM LGST+VLRRRF P L + + S+V
Sbjct 236 SRMPLRYGWRTHIAAPLFHTWGFAHLALAMLLGSTIVLRRRFDPEACLRATQDERCDSLV 295
Query 313 VVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEV 372
V+PVML R++ E+T + DLS +++V SGS L +LAT + G +YN+YGSTEV
Sbjct 296 VIPVMLQRMMALPEETLARYDLSRVQVVASSGSALPGDLATDWMDHFGDHLYNIYGSTEV 355
Query 373 AFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGG 432
A+A+IA P DL+ PS G VKILD +G E+PQG GRIFVGN FEGYTGGG
Sbjct 356 AYASIATPLDLREAPSAAGKPPYATIVKILDPDGRELPQGETGRIFVGNGLLFEGYTGGG 415
Query 433 GKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAA 492
K+++DGL+S+GDVG FD G L+V GRDDEMIVSGGENVFP EVED + H VVE AA
Sbjct 416 HKEVVDGLMSTGDVGRFDTDGRLHVEGRDDEMIVSGGENVFPKEVEDCLMRHDAVVEVAA 475
Query 493 IGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKV 552
+GVDD +FG RLRAFVV + E +K +V+++LARYKVPR+V+FLDELPRN TGKV
Sbjct 476 VGVDDPDFGKRLRAFVVVSRA--VPEQELKDWVKENLARYKVPRDVVFLDELPRNATGKV 533
Query 553 LKREL 557
LKR+L
Sbjct 534 LKRDL 538
>gi|302529170|ref|ZP_07281512.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. AA4]
gi|302438065|gb|EFL09881.1| O-succinylbenzoate-CoA ligase [Streptomyces sp. AA4]
Length=541
Score = 441 bits (1133), Expect = 2e-121, Method: Compositional matrix adjust.
Identities = 229/502 (46%), Positives = 323/502 (65%), Gaps = 7/502 (1%)
Query 57 IRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAI 116
IRK+G ARR ++D+ G LTF +LD+ ++A+A +G+ G +A
Sbjct 45 IRKYGPFAGANHIAARRDSTAVGIVDDLGPLTFKQLDDQSNALARAWSQRGLGPGSVIAA 104
Query 117 LARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQ 176
L R+HR V+ + ++GAR++L+N+ F+ PQ +V+ REG ++YD E+T +
Sbjct 105 LCRDHRGLVVTMAASGKLGARLLLMNTGFAKPQFADVAKREGVTALVYDQEFTGLLDAID 164
Query 177 PPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKG 236
+ + A D+P G LAE+IA + P P ++ ++LTSGTTGTPKG
Sbjct 165 EDVDRYLAW-----VDEPGGHEIPVLAEIIASTDDRPLPAPAKPGGFVLLTSGTTGTPKG 219
Query 237 ANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKP 296
A R LA L +P +AGE T + +P+FH G L+ LG T+V+RR+F P
Sbjct 220 APRPHTSALAS-AQFLDRIPLRAGEATFMGAPLFHGTGLSQFILSFALGCTVVMRRKFDP 278
Query 297 ALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRAL 356
L+ + +H+ T++V+VP ML RI+D ++ + D S L+I+FV+GS L +L RA
Sbjct 279 EATLKGVAQHRCTALVLVPTMLQRIVDLPKEVRDRYDTSCLRIIFVAGSALSPDLGNRAN 338
Query 357 GDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAV-G 415
G V++N+YGSTEVA AT+A P+D + P TVG G V + DE+G ++ + V G
Sbjct 339 EQFGDVVHNLYGSTEVAVATVATPEDWKRAPGTVGRAPVGCRVALYDEHGGKITEPHVTG 398
Query 416 RIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPA 475
R+FVG+ F GYT G K+IIDGLLSSGDVG+FDE GLL++ GRDDEMIVSGGENVFP
Sbjct 399 RVFVGSGLSFGGYTDGRNKEIIDGLLSSGDVGHFDEEGLLFIDGRDDEMIVSGGENVFPI 458
Query 476 EVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVP 535
EVE+L+ DV+EAA IGV+D +FG RL+AFVV+ G+ LDED +++YV+ +LARYKVP
Sbjct 459 EVENLLVEREDVLEAAVIGVEDADFGERLKAFVVRAEGSTLDEDGVREYVKANLARYKVP 518
Query 536 REVIFLDELPRNPTGKVLKREL 557
R+V FLDELPRN TGKVL+ +L
Sbjct 519 RDVEFLDELPRNATGKVLRTKL 540
>gi|257055386|ref|YP_003133218.1| acyl-CoA synthetase [Saccharomonospora viridis DSM 43017]
gi|256585258|gb|ACU96391.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Saccharomonospora
viridis DSM 43017]
Length=539
Score = 437 bits (1124), Expect = 2e-120, Method: Compositional matrix adjust.
Identities = 233/503 (47%), Positives = 329/503 (66%), Gaps = 12/503 (2%)
Query 58 RKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAIL 117
R++G + ARR P+ ++DE G+LT+++LD ++A+A A+GVR G VA+L
Sbjct 45 RRYGPLAGSVKIAARRDPHSVGLVDERGSLTYTQLDLRSNALARAWAARGVRPGTTVAVL 104
Query 118 ARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQP 177
R+HR V+A A ++GA ++LLN+ F+ PQ+ +V+ RE +V+++D+E+T +
Sbjct 105 CRDHRGLVLALLAAGKLGAPVLLLNTGFAKPQLTDVAAREKVRVLVHDEEFTDLLGDIAG 164
Query 178 PLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGA 237
L P D P TL ++IA S P P + +++LTSGTTGTPKGA
Sbjct 165 VDRYLAWTDSTPPADVP------TLDDIIAGSDDHPLPAPPKPGGLVLLTSGTTGTPKGA 218
Query 238 NRNTPPTLAPIGG--ILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFK 295
R P ++P L +P + GE T + +P+FHA G L+ LG T+V+RR+F
Sbjct 219 PR---PKVSPFDSAQFLDRIPLRVGEATFMGAPLFHATGISQFILSCALGCTVVVRRKFD 275
Query 296 PALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRA 355
P L + +H+ T++V+VP ML RILD + + D SSL+I+FV+GS L E+ RA
Sbjct 276 PEATLRGVAEHRCTALVLVPTMLQRILDLGPEVIGRYDTSSLRIIFVAGSALAPEVGNRA 335
Query 356 LGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAV- 414
G VI+N+YGSTEVA AT+A P+D + P TVG G V++ DE+G + + V
Sbjct 336 TELFGDVIHNLYGSTEVAVATVATPEDWKRAPGTVGKPPVGCRVELYDEHGRRITRPYVT 395
Query 415 GRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFP 474
GR+FVG+ FEGYT G K+ I+GLL++GDVG+FD GLL++ GRDDEMIVSGGENV+P
Sbjct 396 GRVFVGSGLAFEGYTDGRTKETINGLLATGDVGHFDADGLLFIDGRDDEMIVSGGENVYP 455
Query 475 AEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKV 534
EVE+++ HPDV EAA IGV D EFG RL+AFVV K GA+LD D ++++VR++LARYKV
Sbjct 456 VEVENVLVEHPDVREAAVIGVPDDEFGQRLKAFVVVKEGAELDADAVREHVRNNLARYKV 515
Query 535 PREVIFLDELPRNPTGKVLKREL 557
PR+V FLD+LPRN TGKVL+ L
Sbjct 516 PRDVEFLDQLPRNATGKVLRNSL 538
>gi|161598438|ref|YP_120711.2| acyl-CoA synthetase [Nocardia farcinica IFM 10152]
Length=544
Score = 437 bits (1123), Expect = 3e-120, Method: Compositional matrix adjust.
Identities = 241/520 (47%), Positives = 327/520 (63%), Gaps = 5/520 (0%)
Query 39 SGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHA 98
SG I L P + R++G L H+AR AP+ A++DE G LT+ ELDE + A
Sbjct 22 SGVIDLSDPGETLRNMRETRQYGPHAALVRHSARVAPDHPALVDERGELTYKELDEQSTA 81
Query 99 VANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREG 158
VA GL A G+ G +A LAR+HR ++A A ++G RI L+N+ F+ PQ EV RE
Sbjct 82 VARGLQAAGITEGMVIAALARDHRGLIMAKVAAGKLGVRIALMNTGFAKPQFAEVCAREK 141
Query 159 AKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKAS 218
+ +++D E+ + P L + V+ + P+G+ +T +LIA +S P P S
Sbjct 142 VQAVLHDSEFLGLLDALPPELPRYLTW-VDEGTEVPAGT--QTFDDLIAANSAEPLPAPS 198
Query 219 RRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHA 278
+ IILTSGTTG PKGA R A + +PF+ ++ SP+FH+ G
Sbjct 199 KPGGFIILTSGTTGLPKGAPRTKVSPFA-TAQFVDRMPFRRFGTMVIVSPIFHSTGLGTW 257
Query 279 ALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLK 338
+ L + +V+RRRF L+ I HKA +V VP ML R+++ E+ K DLSSL+
Sbjct 258 LVGTVLSNKIVMRRRFDAEATLKMIADHKANMLVAVPTMLHRMVELPEEVRAKYDLSSLE 317
Query 339 IVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVT 398
+ ++GS L EL+ RA GPV+YN+YGSTEVA ATIA P++L P TVG
Sbjct 318 SIVLAGSALSPELSIRAAEVFGPVVYNLYGSTEVAIATIAKPEELAVAPGTVGRPPITCD 377
Query 399 VKILDENGNEVPQGAV-GRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYV 457
V++ D+N ++ + V GRIFV + PFEGYT G KQIIDG +SSGDVG+F+E GLL V
Sbjct 378 VRLYDDNDKQIHEKNVTGRIFVRSGAPFEGYTDGRHKQIIDGYMSSGDVGHFEEHGLLMV 437
Query 458 SGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLD 517
GRDD+MIVSGGENV+P EVE+L+ H D+ +AA +GVDD EFG RLRAFVV +PG D
Sbjct 438 DGRDDDMIVSGGENVYPQEVENLLLEHDDIFDAAVVGVDDVEFGKRLRAFVVPEPGKQPD 497
Query 518 EDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
+ IK YV+++LARYKVPR+VIFLD+LPRN TGK+L+R L
Sbjct 498 AEEIKAYVKNNLARYKVPRDVIFLDDLPRNATGKLLRRVL 537
>gi|300788812|ref|YP_003769103.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32]
gi|299798326|gb|ADJ48701.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32]
gi|340530431|gb|AEK45636.1| acyl-CoA synthetase [Amycolatopsis mediterranei S699]
Length=544
Score = 436 bits (1121), Expect = 5e-120, Method: Compositional matrix adjust.
Identities = 235/504 (47%), Positives = 324/504 (65%), Gaps = 6/504 (1%)
Query 57 IRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAI 116
+RK+G +ARR P ++DE G LT+ +LD+ ++A+A +G+R G VA
Sbjct 45 LRKFGPFAGANHISARRDPAAVGIVDELGPLTYKQLDDQSNALARAWSERGIRPGQVVAA 104
Query 117 LARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQ 176
L R+HR V+ + ++G R++L+N+ F+ PQ+ +V+ REG ++YD E+T L
Sbjct 105 LCRDHRGLVLTMAASGKLGVRLLLMNTGFAKPQLADVAQREGVTALVYDQEFTGL--LDA 162
Query 177 PPLGKLRALG-VNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPK 235
P G R L V P D + + L E+IA + P P ++ ++LTSGTTGTPK
Sbjct 163 IPDGVDRYLAWVEPGSDL-TDRTVPVLDEIIASTDDRPWPAPAKPGGFVLLTSGTTGTPK 221
Query 236 GANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFK 295
GA R LA L +P ++ E T + +P+FH G L+ LGS +V+RR+F
Sbjct 222 GAPRPHTSALAS-AQFLDRIPLRSNEATYMGAPLFHGTGLSQFILSFALGSKVVMRRKFN 280
Query 296 PALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRA 355
P L + +HK T++V+VP ML RI+D ++ K D S+L+I+FV+GS L +L RA
Sbjct 281 PEEALRGVAEHKCTALVLVPTMLQRIVDLPKEVRQKYDTSALRIIFVAGSALSPDLGNRA 340
Query 356 LGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAV- 414
GPV++N+YGSTEVA AT+A P+D P TVG G V + D G ++ + V
Sbjct 341 NEAFGPVVHNLYGSTEVAVATVATPEDWAKAPGTVGRAPVGCKVALYDAKGGKITEPNVT 400
Query 415 GRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFP 474
GR+FVG+ F GYT G K+IIDGLLSSGDVG+FDE GLL++ GRDDEMIVSGGENVFP
Sbjct 401 GRVFVGSGLSFGGYTDGRHKEIIDGLLSSGDVGHFDEDGLLFIDGRDDEMIVSGGENVFP 460
Query 475 AEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKV 534
EVE+L+ DV+EAA IGV+D EFG RL+AFVV+ GA+LD D I+ YV+ +LARYKV
Sbjct 461 IEVENLLVEREDVIEAAVIGVEDPEFGQRLKAFVVRAEGAELDADEIRDYVKANLARYKV 520
Query 535 PREVIFLDELPRNPTGKVLKRELR 558
PR+V FLDELPRN TGKVL+ +L+
Sbjct 521 PRDVEFLDELPRNATGKVLRTKLQ 544
>gi|54017977|dbj|BAD59347.1| putative acyl-CoA synthetase [Nocardia farcinica IFM 10152]
Length=527
Score = 436 bits (1121), Expect = 6e-120, Method: Compositional matrix adjust.
Identities = 241/520 (47%), Positives = 327/520 (63%), Gaps = 5/520 (0%)
Query 39 SGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHA 98
SG I L P + R++G L H+AR AP+ A++DE G LT+ ELDE + A
Sbjct 5 SGVIDLSDPGETLRNMRETRQYGPHAALVRHSARVAPDHPALVDERGELTYKELDEQSTA 64
Query 99 VANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREG 158
VA GL A G+ G +A LAR+HR ++A A ++G RI L+N+ F+ PQ EV RE
Sbjct 65 VARGLQAAGITEGMVIAALARDHRGLIMAKVAAGKLGVRIALMNTGFAKPQFAEVCAREK 124
Query 159 AKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKAS 218
+ +++D E+ + P L + V+ + P+G+ +T +LIA +S P P S
Sbjct 125 VQAVLHDSEFLGLLDALPPELPRYLTW-VDEGTEVPAGT--QTFDDLIAANSAEPLPAPS 181
Query 219 RRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHA 278
+ IILTSGTTG PKGA R A + +PF+ ++ SP+FH+ G
Sbjct 182 KPGGFIILTSGTTGLPKGAPRTKVSPFA-TAQFVDRMPFRRFGTMVIVSPIFHSTGLGTW 240
Query 279 ALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLK 338
+ L + +V+RRRF L+ I HKA +V VP ML R+++ E+ K DLSSL+
Sbjct 241 LVGTVLSNKIVMRRRFDAEATLKMIADHKANMLVAVPTMLHRMVELPEEVRAKYDLSSLE 300
Query 339 IVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVT 398
+ ++GS L EL+ RA GPV+YN+YGSTEVA ATIA P++L P TVG
Sbjct 301 SIVLAGSALSPELSIRAAEVFGPVVYNLYGSTEVAIATIAKPEELAVAPGTVGRPPITCD 360
Query 399 VKILDENGNEVPQGAV-GRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYV 457
V++ D+N ++ + V GRIFV + PFEGYT G KQIIDG +SSGDVG+F+E GLL V
Sbjct 361 VRLYDDNDKQIHEKNVTGRIFVRSGAPFEGYTDGRHKQIIDGYMSSGDVGHFEEHGLLMV 420
Query 458 SGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLD 517
GRDD+MIVSGGENV+P EVE+L+ H D+ +AA +GVDD EFG RLRAFVV +PG D
Sbjct 421 DGRDDDMIVSGGENVYPQEVENLLLEHDDIFDAAVVGVDDVEFGKRLRAFVVPEPGKQPD 480
Query 518 EDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
+ IK YV+++LARYKVPR+VIFLD+LPRN TGK+L+R L
Sbjct 481 AEEIKAYVKNNLARYKVPRDVIFLDDLPRNATGKLLRRVL 520
>gi|134098931|ref|YP_001104592.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338]
gi|291009375|ref|ZP_06567348.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338]
gi|133911554|emb|CAM01667.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338]
Length=540
Score = 430 bits (1106), Expect = 3e-118, Method: Compositional matrix adjust.
Identities = 235/541 (44%), Positives = 336/541 (63%), Gaps = 9/541 (1%)
Query 19 IGQYVARGTAELHYLRKIIESGAI-GLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNR 77
I V + H LR + +G I GL AAL ++R+WG + ++AR P+
Sbjct 4 ISDVVRKSAHTAHGLRVMARAGMISGLAVGRALAALK-EVRRWGPLVSALRYSARNRPDV 62
Query 78 AAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGAR 137
V+DE G +T+ ELD + A+A L A+G++AGD A+L R+HRW + + ++GA
Sbjct 63 PGVVDEAGPVTYRELDLRSTALAAALHARGLKAGDTAAVLCRDHRWLIESLLACGKLGAD 122
Query 138 IILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGS 197
++LLN+ F+GPQ+ +V REGA+++++D+E+T V+ A L + A +D PS +
Sbjct 123 VLLLNTGFAGPQLADVLTREGAEILVHDEEFTPVVADAHVSLPRYLAW----NDAGPSRA 178
Query 198 SDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPF 257
ETL EL+ S P R A++++LTSGTTG PKGA R L L +P
Sbjct 179 RPETLEELVCERSEPKLPVPPRPANVVLLTSGTTGLPKGAKREIRSGLTA-ADFLDRIPL 237
Query 258 KAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVM 317
+A E T + +P+FHA+G+ L LGSTLV RRF V+ +E+ + T++V+VP M
Sbjct 238 RARESTFISAPLFHAVGFSQLTLGFALGSTLVFHRRFSVEGVVRAVEEQQCTALVLVPTM 297
Query 318 LSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATI 377
L+RILD + P L+S+++V SGS L L + LG V+YN+YGSTE A ++
Sbjct 298 LNRILDHYGERLSGP-LASVRVVLASGSALPPTLCEQTRRVLGEVLYNLYGSTEAAVVSV 356
Query 378 AGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQ-GAVGRIFVGNAFPFEGYTGGGGKQI 436
A P +L+ P TVG +++ DENG + + G GRIF G A F GYT G G +
Sbjct 357 ATPDELRTAPGTVGRPPHTCALRLEDENGARITRPGVSGRIFAGGALAFSGYTDGAGGDV 416
Query 437 IDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVD 496
GL+ +GD+G+FD GLL+V GR D+MIVSGGENVFP+EVE LI+ H V + A +GVD
Sbjct 417 RGGLIGTGDLGHFDGNGLLFVDGRADDMIVSGGENVFPSEVEHLIARHYQVKDVAVVGVD 476
Query 497 DKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRE 556
D +FG RLRAFVV PG+DL+ D ++ YVR LAR+KVPREV+ +D++PRN TGK+L+R
Sbjct 477 DPDFGQRLRAFVVPIPGSDLEPDEVRDYVRASLARHKVPREVVMVDQVPRNATGKILRRA 536
Query 557 L 557
L
Sbjct 537 L 537
>gi|326330577|ref|ZP_08196884.1| substrate--CoA ligase [Nocardioidaceae bacterium Broad-1]
gi|325951652|gb|EGD43685.1| substrate--CoA ligase [Nocardioidaceae bacterium Broad-1]
Length=554
Score = 430 bits (1105), Expect = 4e-118, Method: Compositional matrix adjust.
Identities = 246/522 (48%), Positives = 324/522 (63%), Gaps = 26/522 (4%)
Query 47 PLNYAALAADIRKWGE------VGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVA 100
PL A + +WG +G+ A R P R A+IDE G+LT++ELD ++A+A
Sbjct 30 PLGLARTGLALARWGTGPAGGFIGL-----AHRYPRRTALIDELGSLTYAELDRRSNAIA 84
Query 101 NGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAK 160
L A+GV GDGVAI+ RNHR FV A A++GA + LN+ F+GPQ+ V +R+
Sbjct 85 RALAARGVGEGDGVAIMCRNHRGFVDATLAVAKLGADALYLNTAFAGPQLVGVLERDKPA 144
Query 161 VIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRR 220
+II+D+E+T +S A +L A D P ETL L++ + AP R
Sbjct 145 LIIHDEEFTGLLSSATSAT-RLVAW---VDSSDPG----ETLESLVSGDARPVAPP-KRH 195
Query 221 ASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAAL 280
I+ILTSGTTG PK A R A I ++S +P K G + +P+FH G H
Sbjct 196 GRIVILTSGTTGAPKSAPRQEAGVDAAIA-LMSRMPMKDGWRCFIAAPLFHTWGIAHLLF 254
Query 281 AMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSS---- 336
A LG+T++LRRRF P L + + KA S VV+PVM+ RIL E+T DL
Sbjct 255 AELLGTTMILRRRFDPEDALATLAETKADSFVVIPVMMQRILSLPEETLAAYDLQGIAFR 314
Query 337 LKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKG 396
LK V SGS L +LA + G +YN+YGSTEV++A+IA P DL+ P++ G V G
Sbjct 315 LKAVASSGSALPGDLALEWMDRFGDSLYNVYGSTEVSYASIADPVDLREAPTSAGKVPWG 374
Query 397 VTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLY 456
+KILD +G VP G GRIFVGN FEGYT GGGK+++DGL+++GDVG F G LY
Sbjct 375 TRMKILDGDGVPVPDGEAGRIFVGNGLLFEGYTSGGGKEVVDGLMATGDVGRFGPDGRLY 434
Query 457 VSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADL 516
V GRDD+MIVSGGENVFP EVED + HP V +AA +GVDD +FG RLR FVV PGA+
Sbjct 435 VEGRDDDMIVSGGENVFPQEVEDCLIRHPLVADAACVGVDDADFGKRLRGFVVLAPGAEG 494
Query 517 DEDTI-KQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
D D + K +V+++LAR+KVPRE++ D LPRN TGKVL+REL
Sbjct 495 DVDAVLKDWVKENLARFKVPREIVVTDALPRNATGKVLRREL 536
>gi|54026470|ref|YP_120712.1| acyl-CoA synthetase [Nocardia farcinica IFM 10152]
gi|54017978|dbj|BAD59348.1| putative acyl-CoA synthetase [Nocardia farcinica IFM 10152]
Length=565
Score = 427 bits (1098), Expect = 2e-117, Method: Compositional matrix adjust.
Identities = 228/509 (45%), Positives = 325/509 (64%), Gaps = 6/509 (1%)
Query 54 AADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDG 113
A ++ K+G + H A+ P+ AA++DE G LTF LDE ++A A GL A+G+R GD
Sbjct 57 AFNVVKFGPFAGVVMHAAQTRPHAAAIVDERGELTFGALDEQSNAFARGLAAQGIRPGDV 116
Query 114 VAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVS 173
VA+LAR+HR V++ ++G R +L+N+ F+ PQ+ V+ RE K +++D E+ +S
Sbjct 117 VAVLARDHRGMVLSLLATGKLGVRAVLMNTGFAAPQLAAVAVREKVKAVLHDSEFVDLMS 176
Query 174 LAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGT 233
+ ++ D P+ TL L A STAP P ++ ++ILTSGTTGT
Sbjct 177 AVPDSVPRILTWVDATDAVDPA---TPTLDSLAAGQSTAPLPTPAKPGGMVILTSGTTGT 233
Query 234 PKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLR-R 292
PKGA R+ A + VP ++ +P+FH G + + LG+ +V + R
Sbjct 234 PKGAPRDRVSPFAS-AQFIDRVPLPRNGTMIMAAPIFHGTGLSQFTIGLALGNRVVFQQR 292
Query 293 RFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELA 352
RF P L +I +++A ++VVVP ML RILD ++ + D+ SLK++F +GS + ++
Sbjct 293 RFDPERTLANIAEYRADALVVVPTMLQRILDLGDEVLDRYDVRSLKVIFAAGSAIPPDVV 352
Query 353 TRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQG 412
TR L +YN+YGSTE A T+A P++L+ P+T G G+ + +LDE+ +
Sbjct 353 TRTLDRFNDSLYNLYGSTECAVMTVATPQELRIAPTTAGKPPVGIRIALLDEDRKPITAP 412
Query 413 AV-GRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGEN 471
V G IFV N F F GYT G K++++G++SSGDVG+FDERGLLY+ GRDD+MIVSGGEN
Sbjct 413 HVTGTIFVDNGFAFSGYTDGRTKEMVNGMMSSGDVGHFDERGLLYIDGRDDDMIVSGGEN 472
Query 472 VFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLAR 531
VFP EVE+LI+G DV EAA +GVDD+EFG RLRAFVV PG+ D IK YV+ +LAR
Sbjct 473 VFPLEVENLIAGRDDVFEAAVVGVDDREFGKRLRAFVVPGPGSARDPQEIKDYVKANLAR 532
Query 532 YKVPREVIFLDELPRNPTGKVLKRELRKL 560
YKVPREVIFLDELPRN TGK+L++ L ++
Sbjct 533 YKVPREVIFLDELPRNATGKLLRKPLAEM 561
>gi|108800723|ref|YP_640920.1| acyl-CoA synthetase [Mycobacterium sp. MCS]
gi|119869862|ref|YP_939814.1| acyl-CoA synthetase [Mycobacterium sp. KMS]
gi|108771142|gb|ABG09864.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS]
gi|119695951|gb|ABL93024.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS]
Length=548
Score = 423 bits (1088), Expect = 4e-116, Method: Compositional matrix adjust.
Identities = 240/552 (44%), Positives = 331/552 (60%), Gaps = 24/552 (4%)
Query 19 IGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLP-SHNARRAPNR 77
+G A+ A + ++ + S I P Y + A +R+ G + + A+R P+R
Sbjct 5 LGDTAAKVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDR 64
Query 78 AAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGD--GVAILARNHRWFVIANYGAARVG 135
+IDE G LTF+ELD+A+ A+A L +G+ G VAI+ RNHR F+ A A R+G
Sbjct 65 PGLIDERGMLTFAELDDASDALAVAL--QGLPGGTPGTVAIMCRNHRGFIEALLAANRIG 122
Query 136 ARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD----- 190
A +LLN+ F+GP + EV++REGA V+IYD+E+++ V RAL PD
Sbjct 123 ANALLLNTSFAGPALAEVAEREGADVVIYDEEFSETVE---------RALSGLPDAVRII 173
Query 191 --DDKPSGSSDETLAELI-AHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLA- 246
D+P G ++ T+ LI AH P P A R + II+LTSGTTGTPKGA R+ A
Sbjct 174 AWTDEPGGGAETTVDALIEAHRGERPRP-AERSSEIILLTSGTTGTPKGAKRSAGSGGAG 232
Query 247 PIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKH 306
+ +L P++A E T++ +PMFHA G+ A L T+V RRRF P L +++H
Sbjct 233 DLKAVLDRTPWRAEETTVIVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEH 292
Query 307 KATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNM 366
KAT ++VVPVM RI+D ++ + SL+ SGS++ ++ T + G VIYN
Sbjct 293 KATGLIVVPVMFDRIMDLPDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNN 352
Query 367 YGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFE 426
Y +TE A P DL+ P T G G ++I D + E+P G G IFV + F+
Sbjct 353 YNATEAGMIATATPADLRAAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFD 412
Query 427 GYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPD 486
GYT G K DG ++SGDVGY DE G L+V GRDDEMIVSGGENV+P EVE ++ HP
Sbjct 413 GYTSGSTKDFHDGFMASGDVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPG 472
Query 487 VVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPR 546
V EA +GVDD+++G RL AFVV GA L D +K++VRD+LA YKVPR+++ LDELPR
Sbjct 473 VAEAEVLGVDDEKYGQRLAAFVVPAAGASLTPDELKEHVRDNLANYKVPRDIVILDELPR 532
Query 547 NPTGKVLKRELR 558
TGKVL+ ELR
Sbjct 533 GGTGKVLRNELR 544
>gi|311744718|ref|ZP_07718515.1| acyl-CoA synthetase [Aeromicrobium marinum DSM 15272]
gi|311312027|gb|EFQ81947.1| acyl-CoA synthetase [Aeromicrobium marinum DSM 15272]
Length=540
Score = 422 bits (1086), Expect = 7e-116, Method: Compositional matrix adjust.
Identities = 228/485 (48%), Positives = 317/485 (66%), Gaps = 11/485 (2%)
Query 75 PNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARV 134
P+ A++D+ G+LT +EL + A+A L A GV AG + IL RNHR F + A+++
Sbjct 63 PHGVAIVDDRGSLTSAELHRRSTALAAALYATGVDAGSSIGILCRNHREFFEVFFAASKL 122
Query 135 GARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKP 194
GAR +LLN++FS PQ+ EV REG V+++D E+ +L P + +L A +
Sbjct 123 GARTLLLNTDFSAPQLTEVCGREGVDVLVHDGEFADRTTLLDPSVRRLVA-------HRE 175
Query 195 SGSSDETLAE--LIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGIL 252
+G D+ A LI H+ P+ R +++LTSGTTGTPKGA R+ TLA GG+L
Sbjct 176 AGDPDDAAATDTLIRHADPRVLPRPRRAQRVVLLTSGTTGTPKGAPRDIDATLAAPGGVL 235
Query 253 SHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMV 312
S +P + G ++ +P+FHA G A L+ LGST+V+ RRF A L + + +A +++
Sbjct 236 SRIPLRPGRTVVVAAPLFHAWGLSMAMLSFGLGSTVVVSRRFDAAATLAAMAERRADTLI 295
Query 313 VVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEV 372
+PV+L R++ +E ++ P L L+++ +SGS L ELA RA GPV++N+YGSTEV
Sbjct 296 TLPVLLGRLVAAVEASDRPPRLQHLRVIALSGSALRPELAERATRAFGPVVHNLYGSTEV 355
Query 373 AFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGG 432
A IA P+DL P TVG G V+ILD+ V GAVGRIFV ++ F GYTGGG
Sbjct 356 AAVAIATPQDLAAAPGTVGRPPFGTVVRILDDRDRPVRHGAVGRIFVRSSMQFGGYTGGG 415
Query 433 GKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAA 492
K+++DG +S+GD+G+ D G L+V GRDD+MIVSGGENVFP EVE+L++ HP V EAA
Sbjct 416 SKRVVDGFMSTGDLGHLDRDGRLHVEGRDDDMIVSGGENVFPLEVENLLATHPSVREAAV 475
Query 493 IGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKV 552
+GV D+EFGARL AFVV + D ++ VR +LARYKVPR+VIF+DELPRNP GKV
Sbjct 476 VGVPDEEFGARLAAFVVVD--GPITADAVRDLVRQNLARYKVPRDVIFVDELPRNPAGKV 533
Query 553 LKREL 557
+KR L
Sbjct 534 VKRLL 538
>gi|126436346|ref|YP_001072037.1| acyl-CoA synthetase [Mycobacterium sp. JLS]
gi|126236146|gb|ABN99546.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS]
Length=548
Score = 422 bits (1085), Expect = 8e-116, Method: Compositional matrix adjust.
Identities = 240/552 (44%), Positives = 331/552 (60%), Gaps = 24/552 (4%)
Query 19 IGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLP-SHNARRAPNR 77
+G A+ A + ++ + S I P Y + A +R+ G + + A+R P+R
Sbjct 5 LGDTAAKVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDR 64
Query 78 AAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGD--GVAILARNHRWFVIANYGAARVG 135
+IDE G LTF+ELD+A+ A+A L +G+ G VAI+ RNHR F+ A A R+G
Sbjct 65 PGLIDERGMLTFAELDDASDALAVAL--QGLPGGTPGTVAIMCRNHRGFIEALLAANRIG 122
Query 136 ARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD----- 190
A +LLN+ F+GP + EV++REGA V+IYD+E+++ V RAL PD
Sbjct 123 ANALLLNTSFAGPALAEVAEREGADVVIYDEEFSETVE---------RALSGLPDAVRII 173
Query 191 --DDKPSGSSDETLAELI-AHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLA- 246
D+P G ++ T+ LI AH P P A R + II+LTSGTTGTPKGA R+ A
Sbjct 174 AWTDEPGGGAETTVDALIEAHRGERPRP-AERSSEIILLTSGTTGTPKGAKRSAGSGGAG 232
Query 247 PIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKH 306
+ +L P++A E T++ +PMFHA G+ A L T+V RRRF P L +++H
Sbjct 233 DLKAVLDRTPWRAEETTVIVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEH 292
Query 307 KATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNM 366
KAT ++VVPVM RI+D ++ + SL+ SGS++ ++ T + G VIYN
Sbjct 293 KATGLIVVPVMFDRIMDLPDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNN 352
Query 367 YGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFE 426
Y +TE A P DL+ P T G G ++I D + E+P G G IFV + F+
Sbjct 353 YNATEAGMIATATPADLRAAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFD 412
Query 427 GYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPD 486
GYT G K DG ++SGDVGY DE G L+V GRDDEMIVSGGENV+P EVE ++ HP
Sbjct 413 GYTSGSTKDFHDGFMASGDVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPG 472
Query 487 VVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPR 546
V EA +GVDD+++G RL AFVV GA L D +K++VRD+LA YKVPR+++ LDELPR
Sbjct 473 VAEAEVLGVDDEKYGQRLAAFVVPAAGAALTPDELKEHVRDNLANYKVPRDIVILDELPR 532
Query 547 NPTGKVLKRELR 558
TGKVL+ ELR
Sbjct 533 GGTGKVLRNELR 544
>gi|317507848|ref|ZP_07965549.1| AMP-binding enzyme [Segniliparus rugosus ATCC BAA-974]
gi|316253890|gb|EFV13259.1| AMP-binding enzyme [Segniliparus rugosus ATCC BAA-974]
Length=706
Score = 421 bits (1083), Expect = 1e-115, Method: Compositional matrix adjust.
Identities = 229/486 (48%), Positives = 316/486 (66%), Gaps = 8/486 (1%)
Query 75 PNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARV 134
PN+ IDE G+LTF E+++ A+A+A G AKG++AGD + L+RNHR V+ A ++
Sbjct 68 PNKIGFIDEHGSLTFKEMNDQANALARGWAAKGLKAGDSIGSLSRNHRGLVLTMVAAGKI 127
Query 135 GARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKP 194
G +++LLN+ F+ PQ+ +V REG K I +D E+ + + P R L +D
Sbjct 128 GVKVLLLNTGFAAPQLVDVMKREGGKAIAFDSEFAGIIE--KLPEDVFRTLVWEGGEDPA 185
Query 195 SGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGG--IL 252
+ T+ E+ A S P + +LTSGTTGTPKGA R + PIG L
Sbjct 186 ATKGLPTIEEVSAGQSRENLPNPGKLGGFTLLTSGTTGTPKGAPRGK---VNPIGSAQFL 242
Query 253 SHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMV 312
VP + G+ L +P+FH G LA+ L T++L+R+F+P L+ IEK+KA +V
Sbjct 243 HRVPLRGGQRFLATAPLFHGTGLSQFILALVLRHTVILQRKFQPEQTLQLIEKYKAQVLV 302
Query 313 VVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEV 372
VVP ML RI+D ++T K D+ S+K++F +GS L +L+TR + G +YN+YGSTEV
Sbjct 303 VVPTMLQRIIDLPKETLDKYDVRSIKVIFAAGSALSPDLSTRIMDHFGDTLYNLYGSTEV 362
Query 373 AFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQG-AVGRIFVGNAFPFEGYTGG 431
A AT+A P +++ P T G GV + +LDENG + + GRIFV + F GYT G
Sbjct 363 AVATVAQPWEMRAAPGTAGRPPVGVKLALLDENGKRITEPFKEGRIFVRSMLSFNGYTDG 422
Query 432 GGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAA 491
K+IIDGL+SSGD+G+FD+ GLLYV GRDD+MIVSGGENVFP EVE L++ HPDV E
Sbjct 423 RNKEIIDGLMSSGDMGHFDDLGLLYVDGRDDDMIVSGGENVFPQEVEHLLTEHPDVFEVC 482
Query 492 AIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGK 551
IGVDD EFG RL+A+V K P +DL +D ++ YV+ HLARYKVP+EV+F+D+LPRN TGK
Sbjct 483 VIGVDDDEFGKRLKAYVAKSPDSDLSQDDVQSYVKAHLARYKVPKEVMFVDKLPRNETGK 542
Query 552 VLKREL 557
VL+R L
Sbjct 543 VLRRVL 548
>gi|269124818|ref|YP_003298188.1| AMP-dependent synthetase and ligase [Thermomonospora curvata
DSM 43183]
gi|268309776|gb|ACY96150.1| AMP-dependent synthetase and ligase [Thermomonospora curvata
DSM 43183]
Length=527
Score = 421 bits (1083), Expect = 1e-115, Method: Compositional matrix adjust.
Identities = 237/537 (45%), Positives = 336/537 (63%), Gaps = 21/537 (3%)
Query 30 LHYLRKIIE-------SGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVID 82
+ +R+++E +G IGL PP A +R +G +G + NA R +R A++D
Sbjct 1 MSRIRQVLEGLTAARRAGLIGL-PPRAVAPSIRALRAYGPLGAAATMNALRFGSRTALVD 59
Query 83 EEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLN 142
E GTLTF++L+ ++A+AN A+G+ V IL RNHR + A AA++GA ++ LN
Sbjct 60 EHGTLTFADLERRSNALANAWRARGLGPASRVGILCRNHRGLLDAMTAAAKIGAGVLFLN 119
Query 143 SEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETL 202
++F GPQ+ + +REG +++D+E+T + A P G+ A D+P G L
Sbjct 120 TDFGGPQLVQTVEREGVTALVHDEEFTPVAAGAPAPQGRFVAW-----TDRPGGGD---L 171
Query 203 AELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLA--PIGGILSHVPFKAG 260
LIA AP P R S++ILTSGT+G PKGA R++ P+ A P+G I+ +PF+ G
Sbjct 172 ERLIAEGDPAPPPAPGRHGSLVILTSGTSGAPKGAPRSSGPSAAWLPVG-IVHRIPFRPG 230
Query 261 EVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSR 320
E + PMFH G + + GS L+LRRRF VL+ +E+H+ ++V VPVMLSR
Sbjct 231 ESVFVGPPMFHGWGLTAMLVTLGTGSVLLLRRRFDADAVLDLLERHRVRALVAVPVMLSR 290
Query 321 ILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGP 380
+L + E +P L L+I+ G+ L LA R + GPV+YN YGSTE + +IA P
Sbjct 291 LLAADARRENRPRLR-LRIIATGGAALSPALAERVMARFGPVLYNFYGSTEASSISIATP 349
Query 381 KDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGL 440
+DL+ P VG G TVKILD +G EVP G G+I + + F GYTGGG K L
Sbjct 350 EDLRAAPGCVGRPTLGTTVKILDASGREVPPGVTGQIHIDSPLRFAGYTGGGTKPTAGKL 409
Query 441 LSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEF 500
++ GD+G+ D G L++ GR D+MIVSGGENV+PAEVE+L++GHP + EAA +GV D+EF
Sbjct 410 MAVGDLGHLDAAGRLFIDGRADDMIVSGGENVYPAEVEELLAGHPGIREAAVVGVPDEEF 469
Query 501 GARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
G RLRA+VV A L E+ +++YV +LARYKVPR+V+F++ELPR TGKVLKR L
Sbjct 470 GQRLRAYVVAADTA-LGEEEVRRYVSANLARYKVPRDVVFVEELPRTSTGKVLKRLL 525
>gi|296392903|ref|YP_003657787.1| AMP-dependent synthetase and ligase [Segniliparus rotundus DSM
44985]
gi|296180050|gb|ADG96956.1| AMP-dependent synthetase and ligase [Segniliparus rotundus DSM
44985]
Length=626
Score = 415 bits (1066), Expect = 1e-113, Method: Compositional matrix adjust.
Identities = 228/486 (47%), Positives = 318/486 (66%), Gaps = 8/486 (1%)
Query 75 PNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARV 134
P++ A+IDE G+LT+ E++E A+A+A G A+G++AGD + ++RNHR V+ A ++
Sbjct 73 PDKTALIDEHGSLTWKEVNEQANALARGWAAQGLKAGDSIGSISRNHRGLVLTMVAAGKI 132
Query 135 GARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKP 194
G +++LLN+ F+ PQ+ +V REGAK I +D E+ + P + LR L +D
Sbjct 133 GVKVLLLNTGFAAPQLIDVMAREGAKAIAFDSEFAGIIHRLPPEV--LRTLVWEGGEDPA 190
Query 195 SGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGG--IL 252
+ + T + A S PK +LTSGTTGTPKGA R + PIG L
Sbjct 191 ATAGLPTAESVSAGHSRENLPKPECLGGFTLLTSGTTGTPKGAPRGK---VNPIGSAQFL 247
Query 253 SHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMV 312
VP + G+ L +P+FH G LA+ L T++L+RRF P L+ IE+HKA +V
Sbjct 248 HRVPLRGGQRFLATAPLFHGTGLSQFILALVLRHTVILQRRFNPEQTLQLIERHKAQVLV 307
Query 313 VVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEV 372
VVP ML RI+D ++T K D+SS+++VF +GS L +L+TR + G +YN+YGSTEV
Sbjct 308 VVPTMLQRIIDLPKETLDKYDVSSIQVVFAAGSALSPDLSTRIMDHFGDTLYNLYGSTEV 367
Query 373 AFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQG-AVGRIFVGNAFPFEGYTGG 431
A AT+A P +++ P T G GV + +LDE+G + + GRIFV + F GYT G
Sbjct 368 AVATVAQPWEMRAAPGTAGRPPVGVKLALLDEHGKRITEPFKEGRIFVRSMLSFNGYTDG 427
Query 432 GGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAA 491
K+IIDGL+SSGDVG+FD+ GLLYV GRDD+MIVSGGENVFP EVE L++ HP+V E
Sbjct 428 RNKEIIDGLMSSGDVGHFDDLGLLYVDGRDDDMIVSGGENVFPQEVEHLLTEHPEVFEVC 487
Query 492 AIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGK 551
IGVDD EFG RL+A+V K G+ LD + ++ +V+ HLARYKVP+EV+F+D+LPRN TGK
Sbjct 488 VIGVDDDEFGKRLKAYVAKAEGSGLDAEGVQAHVKAHLARYKVPKEVVFVDKLPRNETGK 547
Query 552 VLKREL 557
VL+R L
Sbjct 548 VLRRML 553
>gi|111023360|ref|YP_706332.1| acyl-CoA synthetase [Rhodococcus jostii RHA1]
gi|110822890|gb|ABG98174.1| probable O-succinylbenzoate--CoA ligase [Rhodococcus jostii RHA1]
Length=544
Score = 414 bits (1064), Expect = 2e-113, Method: Compositional matrix adjust.
Identities = 232/543 (43%), Positives = 330/543 (61%), Gaps = 21/543 (3%)
Query 31 HYLRKIIESGAIGLEPPLNYAALA------------ADIRKWGEVGMLPSHNARRAPNRA 78
H+L KI ++ +G +N A L +RK+G NA +
Sbjct 5 HFLTKITDT--VGAVRVMNRAGLVPFPRVDQGVRSILAVRKFGPFAGPVHANAEAGLDAV 62
Query 79 AVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARI 138
A+IDE G LT+++++E ++A+ A G+ G + + RNHR V+ AA+ G ++
Sbjct 63 ALIDERGPLTYTDIEEQSNALVRAWQADGITPGSVMGCMCRNHRGLVLTMLAAAKNGTKL 122
Query 139 ILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSS 198
+L+N+ F+ PQ+ +V+ RE + +YDDE+ AV+ A P ++ A +DD S S
Sbjct 123 VLMNTGFARPQLVDVAAREQVQAFVYDDEF-HAVAEALP--DEVIAYRSWVEDD--STSQ 177
Query 199 DETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFK 258
TL +++ + P S + ++LTSGTTGTPKGA R LA L VP +
Sbjct 178 VRTLDDVMEGRDRSSLPAPSTQGGFVLLTSGTTGTPKGAPRGHTSPLAS-AQFLDRVPLR 236
Query 259 AGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVML 318
G+ ++ +P FH G ALA+ LG T+V+ R+F P + +EKH+ ++VVVP ML
Sbjct 237 RGQTMMMAAPAFHGTGVSQFALALALGQTVVMHRKFDPENTIRLVEKHRCDTLVVVPTML 296
Query 319 SRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIA 378
RI+D +T K D SSLKI+F +GS L +L R G V++N+YGSTEVA AT+A
Sbjct 297 QRIIDLGPETLAKYDTSSLKIIFAAGSALSPDLCKRTTAAFGEVLHNLYGSTEVAVATVA 356
Query 379 GPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQ-GAVGRIFVGNAFPFEGYTGGGGKQII 437
P DL P T G V++ DE+G + + VGRIFV + F GYT G K+ I
Sbjct 357 TPADLALAPGTAGRAPVTCHVELYDESGQRITEPETVGRIFVASGLSFAGYTDGRDKERI 416
Query 438 DGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDD 497
+GLLS+GDVG+FD GLL+V GRDD+MIVSGGENV+P EVE+L++ DV+EAA IGV+D
Sbjct 417 NGLLSTGDVGHFDRNGLLFVDGRDDDMIVSGGENVYPLEVENLLADREDVLEAAVIGVED 476
Query 498 KEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKREL 557
EFG RLRAFVV PG+ D D +K +V+ +LARYKVPRE+IF++ELPRN TGK+L+R L
Sbjct 477 SEFGHRLRAFVVPGPGSAKDADELKAHVKSNLARYKVPREIIFIEELPRNATGKLLRRVL 536
Query 558 RKL 560
++
Sbjct 537 IEM 539
>gi|254818395|ref|ZP_05223396.1| acyl-CoA synthetase [Mycobacterium intracellulare ATCC 13950]
Length=535
Score = 413 bits (1062), Expect = 4e-113, Method: Compositional matrix adjust.
Identities = 233/529 (45%), Positives = 320/529 (61%), Gaps = 21/529 (3%)
Query 39 SGAIGLEPPLNYAALAADIRKWGEVGMLP--SHNARRAPNRAAVIDEEGTLTFSELDEAA 96
+G I P Y +AA +R+ G +GM + A+R P+R +IDE G+LT+ ELDE
Sbjct 14 AGLIAPMRPDRYVRIAAAMRREG-MGMTSGFASAAQRCPDRPGLIDERGSLTWRELDERC 72
Query 97 HAVANGLLAKGVRAGDG--VAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVS 154
+A+A L +G+ +G + I+ RNHR FV A A R+G+ I+LLN+ F+GP + +V
Sbjct 73 NALAAAL--QGLPSGQPRVIGIMCRNHRGFVEALVAADRIGSDILLLNTSFAGPALADVV 130
Query 155 DREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSD----ETLAELIAHSS 210
REG +IYD+E+T+ V RAL PD + +D T+ LIA +
Sbjct 131 TREGVDAVIYDEEFTETVD---------RALAGTPDATRIVAWTDAEHERTVEGLIAARA 181
Query 211 TAPAPKASRRASIIILTSGTTGTPKGANRNTPPT-LAPIGGILSHVPFKAGEVTLLPSPM 269
A + R+ +I+LTSGTTGTPKGA ++ + + IL P++A E ++ +PM
Sbjct 182 GAQPQRTGRKGKMILLTSGTTGTPKGAKQSGGNAGIGTLKAILDRTPWRAEEPIVIVAPM 241
Query 270 FHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTE 329
FHA G+ LA ++ RR+F P L+ I++HKAT +VVVPVM RI+D +
Sbjct 242 FHAWGFSQLLLAASFACPVITRRKFDPEATLDLIDRHKATGLVVVPVMFDRIMDLPAEVR 301
Query 330 PKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPST 389
+ SL+ SGS++ ++ T + + G VIYN Y +TE A P DL+ P T
Sbjct 302 RRYSGRSLRFAAASGSRMRPDVVTAFMDEFGDVIYNNYNATEAGMIATATPADLRAAPDT 361
Query 390 VGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYF 449
G G ++ILD NE+P G VG I+V N F+GYT G K G +SSGDVGY
Sbjct 362 AGRPAGGTEIRILDPEFNELPAGEVGSIYVRNNTQFDGYTSGSTKDFHAGFMSSGDVGYL 421
Query 450 DERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVV 509
D G L+V GRDDEMIVSGGENV+P EVE ++ HPDV EAA IGVDD+++G RL AFVV
Sbjct 422 DSAGRLFVVGRDDEMIVSGGENVYPIEVEKALAAHPDVAEAAVIGVDDEQYGQRLAAFVV 481
Query 510 KKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558
+PGA D +KQ+VRD+LA YKVPRE+ LDELPR+ TGK+L+ ELR
Sbjct 482 LEPGAGATPDALKQHVRDNLANYKVPREIAVLDELPRSSTGKILRAELR 530
>gi|226305728|ref|YP_002765688.1| fatty-acid--CoA ligase [Rhodococcus erythropolis PR4]
gi|229491011|ref|ZP_04384844.1| acyl-CoA synthase [Rhodococcus erythropolis SK121]
gi|226184845|dbj|BAH32949.1| putative fatty-acid--CoA ligase [Rhodococcus erythropolis PR4]
gi|229322127|gb|EEN87915.1| acyl-CoA synthase [Rhodococcus erythropolis SK121]
Length=544
Score = 413 bits (1061), Expect = 4e-113, Method: Compositional matrix adjust.
Identities = 219/507 (44%), Positives = 311/507 (62%), Gaps = 5/507 (0%)
Query 55 ADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGV 114
A + K+G +A + A+IDE G +T++EL+ ++A+ A G+ + +
Sbjct 37 AAVDKYGPFAGPVHAHAENGYDAVAIIDERGPITYAELERQSNALVRAWQADGITSDSVM 96
Query 115 AILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSL 174
+ RNHR V+ AA+ G +++L+N+ F+ PQ+ +V+ RE +YDDE+
Sbjct 97 GAMCRNHRGLVLTMLAAAKNGTKLVLMNTGFARPQLVDVAAREKVVAFVYDDEFADIADA 156
Query 175 AQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTP 234
+ R+ P+ GS+ TL E IA +T+ P + ++LTSGTTGTP
Sbjct 157 LPDDVVVYRSW---PEGTAADGSTAATLDEAIAGRTTSSVPAPEKNGGFVLLTSGTTGTP 213
Query 235 KGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRF 294
KGA R LA L VP + G+ ++ +P FH G ALA+ LG T+V+ R+F
Sbjct 214 KGAPRGHTSPLAS-AQFLDRVPLRRGQTMMMAAPAFHGTGVSQFALALALGQTVVMHRKF 272
Query 295 KPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATR 354
P ++ + ++K S+VVVP ML+RI+D K D S+LKI+F +GS L +L R
Sbjct 273 DPENTIKLVAQYKCDSLVVVPTMLTRIIDLGPDVLSKYDTSNLKIIFSAGSSLSPDLCKR 332
Query 355 ALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQ-GA 413
G V+YN+YGSTEVA AT+A P+DL P T G V++ DEN ++
Sbjct 333 VTASFGYVLYNLYGSTEVAVATVATPEDLTIAPGTAGRAPVTCHVELFDENNKKITTPHT 392
Query 414 VGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVF 473
+GRIFV + FEGYT G K+ IDGLLS+GDVG+FD GLL+V GRDD+MIVSGGENV+
Sbjct 393 IGRIFVASGLSFEGYTDGRDKERIDGLLSTGDVGHFDANGLLFVDGRDDDMIVSGGENVY 452
Query 474 PAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYK 533
P EVE+L++ DV+EAA IGV+D +FG RLRAFVV GAD + D +K +VR +LARYK
Sbjct 453 PLEVENLLADREDVLEAAVIGVEDADFGHRLRAFVVVAHGADQNSDELKDHVRSNLARYK 512
Query 534 VPREVIFLDELPRNPTGKVLKRELRKL 560
VPRE++F+DELPRN TGK+L+R L ++
Sbjct 513 VPREIVFIDELPRNATGKLLRRVLIEM 539
>gi|333918709|ref|YP_004492290.1| acyl-CoA synthetase [Amycolicicoccus subflavus DQS3-9A1]
gi|333480930|gb|AEF39490.1| acyl-CoA synthetase [Amycolicicoccus subflavus DQS3-9A1]
Length=557
Score = 413 bits (1061), Expect = 5e-113, Method: Compositional matrix adjust.
Identities = 232/510 (46%), Positives = 320/510 (63%), Gaps = 26/510 (5%)
Query 64 GMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRW 123
G L + ARR P+ AVID+ GT+T+ ELD A A+A L+ KGV GD + ILARNHR
Sbjct 49 GGLIAFGARRNPDHPAVIDDAGTITYGELDATADALARSLVQKGVEPGDRIGILARNHRG 108
Query 124 FVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAV----SLAQPPL 179
F+ +AR+G +++LN+ S Q+ +V + + D+E+T+ + S AQ L
Sbjct 109 FLQLIGASARLGTDLVMLNTGASSGQLVDVLREQKLVWLFLDEEFTELLPEDFSDAQVAL 168
Query 180 GKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKAS--------RRASIIILTSGTT 231
P D T+ +LI APAPK+ RR I+LTSGTT
Sbjct 169 SWADTGSSAPRDGW------TTMTQLI---DEAPAPKSPEAKLPARPRRGKTIVLTSGTT 219
Query 232 GTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLR 291
GTPKGA R P + P +LS P + EV+ + +P+FH G+ + + L STLV++
Sbjct 220 GTPKGARRPEPRSWMPASALLSRFPLHSKEVSFIAAPIFHTWGFATVQINLALRSTLVMQ 279
Query 292 RRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAEL 351
R+F P L + KH+A S+ +VP ML RI+D EK + DLS L+++ SGS + L
Sbjct 280 RKFSPKDTLRLVSKHRAASLFLVPTMLHRIVDLPEK-DRDVDLSHLRVIAASGSAIPTGL 338
Query 352 ATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQ 411
R L +LGPV+YN+YGSTEV++A IA P +L P+T G G VKILD++GNEVP
Sbjct 339 VKRTLDELGPVLYNLYGSTEVSWAAIATPDELLDYPTTTGRAPLGTVVKILDDDGNEVPN 398
Query 412 GAVGRIFVGNAFPFEGYTGGGGKQIIDG-LLSSGDVGYFDERGLLYVSGRDDEMIVSGGE 470
G VG IFVGN FEGYT G Q + G L+S+GD+G+ ++ GLL++ GR D+MIVSGGE
Sbjct 399 GEVGNIFVGNGMIFEGYTREGADQEVRGNLMSTGDLGHLNDEGLLFIDGRSDDMIVSGGE 458
Query 471 NVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGA---DLDEDTIKQYVRD 527
NV+P EVE+++S V+E+ +GVDD +FG RL A+VV+K G LDED+IK +V+D
Sbjct 459 NVYPREVENVLSELDGVLESTVVGVDDDDFGKRLAAYVVRKEGQAGDQLDEDSIKAHVKD 518
Query 528 HLARYKVPREVIFLDELPRNPTGKVLKREL 557
LARY +PR+V+FL+ELPRN TGKV+ R+L
Sbjct 519 KLARYSIPRDVVFLEELPRNATGKVVPRDL 548
>gi|226365862|ref|YP_002783645.1| acyl-CoA synthetase [Rhodococcus opacus B4]
gi|226244352|dbj|BAH54700.1| putative acid--CoA ligase [Rhodococcus opacus B4]
Length=544
Score = 411 bits (1056), Expect = 2e-112, Method: Compositional matrix adjust.
Identities = 222/502 (45%), Positives = 313/502 (63%), Gaps = 7/502 (1%)
Query 57 IRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAI 116
+RK+G NA + A+IDE G LT+++++E ++A+ G A G+ G +
Sbjct 41 VRKYGPFAGPVHANAEAGLDAVAIIDERGPLTYADIEEQSNALVRGWQADGITPGSVMGC 100
Query 117 LARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQ 176
+ RNHR V+ AA+ G +++L+N+ F+ PQ+ +V+ RE + +YDDE+ AV+ A
Sbjct 101 MCRNHRGLVLTMLAAAKNGTKLVLMNTGFARPQLVDVAAREQVQAFVYDDEF-HAVAEAL 159
Query 177 PPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKG 236
P ++ +DD S S TL +++ A P S ++LTSGTTGTPKG
Sbjct 160 P--DEVLVYRSWAEDD--STSRVRTLDDVMEGRDRASLPAPSALGGFVLLTSGTTGTPKG 215
Query 237 ANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKP 296
A R LA L VP + G+ ++ +P FH G ALA+ LG T+ + R+F P
Sbjct 216 APRGHTSPLAS-AQFLDRVPLRRGQTMMMAAPAFHGTGVSQFALALALGQTVAMHRKFDP 274
Query 297 ALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRAL 356
+ +EKH+ ++VVVP ML RI+D +T K D SSLKI+F +GS L +L R
Sbjct 275 ENTIRLVEKHRCDTLVVVPTMLQRIIDLGPETLAKYDTSSLKIIFAAGSALSPDLCKRTT 334
Query 357 GDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQ-GAVG 415
G V++N+YGSTEVA AT+A P DL+ P T G V++ DE+ + + VG
Sbjct 335 AAFGKVLHNLYGSTEVAVATVATPADLELAPGTAGRAPVTCHVELYDESSRRITEPETVG 394
Query 416 RIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPA 475
RIFV + F GYT G K+ I+GLLS+GDVG+FD GLL+V GRDD+MIVSGGENV+P
Sbjct 395 RIFVASGLSFSGYTDGRDKERINGLLSTGDVGHFDRNGLLFVDGRDDDMIVSGGENVYPL 454
Query 476 EVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVP 535
EVE+L++ DV+EAA IGV+D EFG RLRAFVV PG+ D + +K +V+ +LARYKVP
Sbjct 455 EVENLLADREDVLEAAVIGVEDSEFGHRLRAFVVPAPGSAKDAEEMKAHVKSNLARYKVP 514
Query 536 REVIFLDELPRNPTGKVLKREL 557
RE+IF++ELPRN TGK+L+R L
Sbjct 515 REIIFIEELPRNATGKLLRRVL 536
>gi|134097880|ref|YP_001103541.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338]
gi|133910503|emb|CAM00616.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338]
Length=551
Score = 409 bits (1051), Expect = 6e-112, Method: Compositional matrix adjust.
Identities = 228/550 (42%), Positives = 325/550 (60%), Gaps = 19/550 (3%)
Query 12 VSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLP---- 67
+ +L++++ ARG + L + G+ P+ L +R W G+ P
Sbjct 5 MRRLRQAVRPERARGLQTAYILARQ------GVVRPMRPDKLLRILRAWLRWGITPPLAY 58
Query 68 SHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIA 127
+ A R P+R AVIDE G ++++E+ +ANGL +G+ V IL RNH +
Sbjct 59 AVGAIRHPDRPAVIDERGAISYAEVSLRTTRLANGLRERGIGESSRVGILCRNHHGAIET 118
Query 128 NYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGV 187
++G ++LLN+ S Q+ V + +++ D EY + + L + A
Sbjct 119 IVACGKLGTDVVLLNTGLSSSQLAAVLAEQRVDLLVLDAEYDRHLPELPADLDVVLAW-- 176
Query 188 NPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP 247
+ T+ LIA S P+ R A +I+LTSGTTGTPKGA R PP + P
Sbjct 177 -----TEGSTRHWTVEHLIATSQAKALPRRPRHARMIVLTSGTTGTPKGARRPDPPGIGP 231
Query 248 IGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHK 307
++S +P ++GE L+ +P+FH G L LG+TLVL RRF+P L ++++
Sbjct 232 AATVMSRIPLRSGERMLVCAPVFHTWGLAAFQLGAVLGATLVLPRRFEPGHALSVAKRYQ 291
Query 308 ATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMY 367
TSM VPVML RILD + +P+ SL++V SGS + A+LATR GPV+YN+Y
Sbjct 292 CTSMFAVPVMLQRILDLPAEERIRPE--SLRVVASSGSAMPADLATRFQRAFGPVLYNLY 349
Query 368 GSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEG 427
GSTEV++ +IA P +L+ PST G +G TV+ILDENG GA GRIF GN FEG
Sbjct 350 GSTEVSWVSIATPSELRAAPSTAGRPPRGTTVRILDENGKPARTGATGRIFAGNDMLFEG 409
Query 428 YTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDV 487
YT GG K+++DGL+S+GD+G D G L+V GR+D+MI+SGGENV+P E ED I+ P+V
Sbjct 410 YTSGGRKEVVDGLMSTGDLGRIDSSGRLFVVGREDDMIISGGENVYPKETEDAIAALPEV 469
Query 488 VEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRN 547
E A +GV+D EFG RL AFVV + LD D +++ VR L+R+ +PR+V+FLDELPRN
Sbjct 470 REVAVVGVEDAEFGQRLAAFVVLQDDTRLDGDDLRERVRGSLSRFAMPRDVVFLDELPRN 529
Query 548 PTGKVLKREL 557
TGKV+ REL
Sbjct 530 ATGKVVPREL 539
>gi|291007402|ref|ZP_06565375.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338]
Length=547
Score = 409 bits (1051), Expect = 7e-112, Method: Compositional matrix adjust.
Identities = 228/550 (42%), Positives = 325/550 (60%), Gaps = 19/550 (3%)
Query 12 VSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLP---- 67
+ +L++++ ARG + L + G+ P+ L +R W G+ P
Sbjct 1 MRRLRQAVRPERARGLQTAYILARQ------GVVRPMRPDKLLRILRAWLRWGITPPLAY 54
Query 68 SHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIA 127
+ A R P+R AVIDE G ++++E+ +ANGL +G+ V IL RNH +
Sbjct 55 AVGAIRHPDRPAVIDERGAISYAEVSLRTTRLANGLRERGIGESSRVGILCRNHHGAIET 114
Query 128 NYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGV 187
++G ++LLN+ S Q+ V + +++ D EY + + L + A
Sbjct 115 IVACGKLGTDVVLLNTGLSSSQLAAVLAEQRVDLLVLDAEYDRHLPELPADLDVVLAW-- 172
Query 188 NPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP 247
+ T+ LIA S P+ R A +I+LTSGTTGTPKGA R PP + P
Sbjct 173 -----TEGSTRHWTVEHLIATSQAKALPRRPRHARMIVLTSGTTGTPKGARRPDPPGIGP 227
Query 248 IGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHK 307
++S +P ++GE L+ +P+FH G L LG+TLVL RRF+P L ++++
Sbjct 228 AATVMSRIPLRSGERMLVCAPVFHTWGLAAFQLGAVLGATLVLPRRFEPGHALSVAKRYQ 287
Query 308 ATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMY 367
TSM VPVML RILD + +P+ SL++V SGS + A+LATR GPV+YN+Y
Sbjct 288 CTSMFAVPVMLQRILDLPAEERIRPE--SLRVVASSGSAMPADLATRFQRAFGPVLYNLY 345
Query 368 GSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEG 427
GSTEV++ +IA P +L+ PST G +G TV+ILDENG GA GRIF GN FEG
Sbjct 346 GSTEVSWVSIATPSELRAAPSTAGRPPRGTTVRILDENGKPARTGATGRIFAGNDMLFEG 405
Query 428 YTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDV 487
YT GG K+++DGL+S+GD+G D G L+V GR+D+MI+SGGENV+P E ED I+ P+V
Sbjct 406 YTSGGRKEVVDGLMSTGDLGRIDSSGRLFVVGREDDMIISGGENVYPKETEDAIAALPEV 465
Query 488 VEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRN 547
E A +GV+D EFG RL AFVV + LD D +++ VR L+R+ +PR+V+FLDELPRN
Sbjct 466 REVAVVGVEDAEFGQRLAAFVVLQDDTRLDGDDLRERVRGSLSRFAMPRDVVFLDELPRN 525
Query 548 PTGKVLKREL 557
TGKV+ REL
Sbjct 526 ATGKVVPREL 535
>gi|333920255|ref|YP_004493836.1| AMP-dependent synthetase and ligase [Amycolicicoccus subflavus
DQS3-9A1]
gi|333482476|gb|AEF41036.1| AMP-dependent synthetase and ligase [Amycolicicoccus subflavus
DQS3-9A1]
Length=546
Score = 409 bits (1050), Expect = 8e-112, Method: Compositional matrix adjust.
Identities = 227/508 (45%), Positives = 309/508 (61%), Gaps = 5/508 (0%)
Query 54 AADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDG 113
A + + +G + R+ N AV DE G LT+ ELD+ + A+A + G+ G
Sbjct 39 AKNSKVYGPQATMAIQGGRKYANLPAVADERGELTYGELDKQSTALARAMKELGLSEGSA 98
Query 114 VAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVS 173
V ILAR+HR +++ A + G R++L+N+ F+ PQ EV RE K I++D E+ +
Sbjct 99 VGILARDHRGLLLSMCAAGKAGIRLVLMNTGFAKPQFAEVCKREQVKAILHDSEFLGLLD 158
Query 174 LAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGT 233
P L ++ DD +S + LIA ST P P + A +ILTSGTTG
Sbjct 159 ALPPELPRILTWVDEDDDVPEDAAS---IDALIASRSTDPLPAPKKPAGFVILTSGTTGL 215
Query 234 PKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRR 293
PKGA R+ LA ++ +PF ++ SP+FH+ G ++ LG+ +V RR
Sbjct 216 PKGAPRDKVTPLA-TAQVVDRIPFPRQGSVVIVSPIFHSTGLATWLISAALGNKVVTMRR 274
Query 294 FKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELAT 353
FK L+ I HKA +V VP ML R+++ KT K D SSLK + ++GS L ELAT
Sbjct 275 FKAEAALKAIADHKAEMLVAVPTMLHRMVELDAKTRAKYDTSSLKAIVLAGSALTPELAT 334
Query 354 RALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVP-QG 412
RA G V+YN+YGSTE A AT+A P +L+ P TVG V + DEN +
Sbjct 335 RAQDTFGDVLYNLYGSTECAIATVANPSELRRAPGTVGRSPITCEVVLFDENDQRITGSN 394
Query 413 AVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENV 472
GRIF+ + PFEGYT G KQIIDG +SSGD+G+FDE GLL+V GRDD+M+VSGGENV
Sbjct 395 KRGRIFIRSGAPFEGYTDGRHKQIIDGFMSSGDMGHFDEDGLLFVDGRDDDMVVSGGENV 454
Query 473 FPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARY 532
FP EVE+L+ D+ +AA +GVDD EFG RLRAFVV + + D + IKQYV+ +LARY
Sbjct 455 FPQEVENLLVERDDISDAAVVGVDDVEFGKRLRAFVVPEANSAKDPEEIKQYVKSNLARY 514
Query 533 KVPREVIFLDELPRNPTGKVLKRELRKL 560
KVPR+V+FLDELPRN TGK+L+R L ++
Sbjct 515 KVPRDVVFLDELPRNATGKLLRRVLVEM 542
>gi|339298042|gb|AEJ50152.1| acyl-CoA synthetase [Mycobacterium tuberculosis CCDC5180]
Length=527
Score = 409 bits (1050), Expect = 8e-112, Method: Compositional matrix adjust.
Identities = 227/494 (46%), Positives = 302/494 (62%), Gaps = 16/494 (3%)
Query 71 ARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYG 130
ARR P+R +IDE GTLT+ +LDE +A+A L A V I+ RNHR FV A
Sbjct 41 ARRCPDRPGLIDELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLA 100
Query 131 AARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPD 190
R+GA I+LLN+ F+GP + EV REG ++YD+E++ V RAL P
Sbjct 101 VNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATVD---------RALAEKPQ 151
Query 191 DDKPSGSSDE----TLAELIA-HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTL 245
+ +DE T+ +L+A H+ P S +I+LTSGTTGTPKGA R++ +
Sbjct 152 ATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSH-GKVILLTSGTTGTPKGA-RHSGGGI 209
Query 246 APIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEK 305
+ IL P++A EVT++ +PMFHA G+ LA L T+V RRRF P L+ I++
Sbjct 210 GTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDR 269
Query 306 HKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYN 365
H AT +VVVPVM RI+D + + D SL+ SGS++ ++ + G VIYN
Sbjct 270 HHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYN 329
Query 366 MYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPF 425
Y +TE A P DL+ P T G +G ++ILD+ EVP G VG I+V N F
Sbjct 330 NYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQF 389
Query 426 EGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHP 485
+GYT G K G +SSGDVGY DE G L+V GRDDEMIVSGGEN++P EVE ++ HP
Sbjct 390 DGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHP 449
Query 486 DVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELP 545
DV EAA IGVDD+++G RL AFVV KPG +T+KQ+VRD+LA YKVPR++ LDELP
Sbjct 450 DVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELP 509
Query 546 RNPTGKVLKRELRK 559
R TGK+L+ EL+
Sbjct 510 RGITGKILRTELQS 523
Lambda K H
0.317 0.137 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 1249804985370
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40