BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0273c Length=206 Score E Sequences producing significant alignments: (Bits) Value gi|308231508|ref|ZP_07663875.1| transcriptional regulator [Mycob... 425 2e-117 gi|15607414|ref|NP_214787.1| transcriptional regulatory protein ... 423 6e-117 gi|308369349|ref|ZP_07666721.1| transcriptional regulator [Mycob... 422 1e-116 gi|344218092|gb|AEM98722.1| transcriptional regulatory protein [... 419 1e-115 gi|289756340|ref|ZP_06515718.1| transcriptional regulatory prote... 419 1e-115 gi|118616911|ref|YP_905243.1| transcriptional regulatory protein... 337 4e-91 gi|118463028|ref|YP_884008.1| TetR family transcriptional regula... 335 3e-90 gi|254820801|ref|ZP_05225802.1| hypothetical protein MintA_12783... 334 5e-90 gi|336460173|gb|EGO39078.1| transcriptional regulator [Mycobacte... 334 5e-90 gi|41409816|ref|NP_962652.1| hypothetical protein MAP3718c [Myco... 330 6e-89 gi|183980561|ref|YP_001848852.1| transcriptional regulatory prot... 322 2e-86 gi|342859255|ref|ZP_08715909.1| hypothetical protein MCOL_10263 ... 322 2e-86 gi|240168492|ref|ZP_04747151.1| transcriptional regulatory prote... 320 9e-86 gi|333988902|ref|YP_004521516.1| transcriptional regulator [Myco... 313 1e-83 gi|120401431|ref|YP_951260.1| TetR family transcriptional regula... 277 8e-73 gi|289764392|ref|ZP_06523770.1| predicted protein [Mycobacterium... 270 1e-70 gi|169631409|ref|YP_001705058.1| transcriptional regulator TetR ... 260 7e-68 gi|118470523|ref|YP_885017.1| TetR family transcriptional regula... 254 4e-66 gi|304310725|ref|YP_003810323.1| Transcriptional regulator [gamm... 195 3e-48 gi|326384397|ref|ZP_08206078.1| transcriptional regulator TetR [... 192 4e-47 gi|333988724|ref|YP_004521338.1| transcriptional regulator [Myco... 166 1e-39 gi|296269494|ref|YP_003652126.1| TetR family transcriptional reg... 132 3e-29 gi|169627418|ref|YP_001701067.1| TetR family transcriptional reg... 119 2e-25 gi|269125208|ref|YP_003298578.1| TetR family transcriptional reg... 119 4e-25 gi|343928644|ref|ZP_08768089.1| putative TetR family transcripti... 110 1e-22 gi|262203327|ref|YP_003274535.1| TetR family transcriptional reg... 109 3e-22 gi|296169199|ref|ZP_06850852.1| transcriptional regulator [Mycob... 102 2e-20 gi|288922539|ref|ZP_06416721.1| transcriptional regulator, TetR ... 100 9e-20 gi|271961895|ref|YP_003336091.1| TetR family transcriptional reg... 98.2 6e-19 gi|118470247|ref|YP_886432.1| TetR family transcriptional regula... 97.8 9e-19 gi|240168590|ref|ZP_04747249.1| hypothetical protein MkanA1_0471... 96.7 2e-18 gi|333991495|ref|YP_004524109.1| transcriptional regulator [Myco... 93.2 2e-17 gi|118462296|ref|YP_883179.1| TetR family transcriptional regula... 93.2 2e-17 gi|336459353|gb|EGO38296.1| transcriptional regulator [Mycobacte... 93.2 2e-17 gi|41409293|ref|NP_962129.1| hypothetical protein MAP3195 [Mycob... 92.8 3e-17 gi|254821128|ref|ZP_05226129.1| hypothetical protein MintA_14422... 92.4 4e-17 gi|254776448|ref|ZP_05217964.1| hypothetical protein MaviaA2_175... 91.3 8e-17 gi|342861045|ref|ZP_08717694.1| hypothetical protein MCOL_19277 ... 91.3 8e-17 gi|315445415|ref|YP_004078294.1| TetR family transcriptional reg... 89.4 3e-16 gi|145225046|ref|YP_001135724.1| TetR family transcriptional reg... 87.8 9e-16 gi|120402891|ref|YP_952720.1| TetR family transcriptional regula... 86.3 3e-15 gi|108798557|ref|YP_638754.1| TetR family transcriptional regula... 80.9 1e-13 gi|183981507|ref|YP_001849798.1| transcriptional regulatory prot... 80.1 2e-13 gi|118617937|ref|YP_906269.1| transcriptional regulatory protein... 79.0 4e-13 gi|291439099|ref|ZP_06578489.1| conserved hypothetical protein [... 76.6 2e-12 gi|300782957|ref|YP_003763248.1| TetR family transcriptional reg... 74.3 1e-11 gi|302524320|ref|ZP_07276662.1| predicted protein [Streptomyces ... 70.9 1e-10 gi|329936770|ref|ZP_08286477.1| A-factor receptor-like protein [... 69.7 3e-10 gi|148556307|ref|YP_001263889.1| TetR family transcriptional reg... 63.9 1e-08 gi|29827923|ref|NP_822557.1| TetR family transcriptional regulat... 62.8 3e-08 >gi|308231508|ref|ZP_07663875.1| transcriptional regulator [Mycobacterium tuberculosis SUMu001] gi|308379735|ref|ZP_07669037.1| transcriptional regulator [Mycobacterium tuberculosis SUMu010] gi|308380936|ref|ZP_07491574.2| transcriptional regulator [Mycobacterium tuberculosis SUMu011] gi|308217196|gb|EFO76595.1| transcriptional regulator [Mycobacterium tuberculosis SUMu001] gi|308356098|gb|EFP44949.1| transcriptional regulator [Mycobacterium tuberculosis SUMu010] gi|308360052|gb|EFP48903.1| transcriptional regulator [Mycobacterium tuberculosis SUMu011] Length=213 Score = 425 bits (1092), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 206/206 (100%), Positives = 206/206 (100%), Gaps = 0/206 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR Sbjct 8 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 67 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA Sbjct 68 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 127 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ Sbjct 128 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 187 Query 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 PDDQACIQTLANIYYRAIYSKEDSSN Sbjct 188 PDDQACIQTLANIYYRAIYSKEDSSN 213 >gi|15607414|ref|NP_214787.1| transcriptional regulatory protein [Mycobacterium tuberculosis H37Rv] gi|15839654|ref|NP_334691.1| hypothetical protein MT0286 [Mycobacterium tuberculosis CDC1551] gi|31791451|ref|NP_853944.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97] 53 more sequence titles Length=206 Score = 423 bits (1088), Expect = 6e-117, Method: Compositional matrix adjust. Identities = 205/206 (99%), Positives = 206/206 (100%), Gaps = 0/206 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 +PDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR Sbjct 1 MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA Sbjct 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ Sbjct 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 Query 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 PDDQACIQTLANIYYRAIYSKEDSSN Sbjct 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 >gi|308369349|ref|ZP_07666721.1| transcriptional regulator [Mycobacterium tuberculosis SUMu002] gi|308370356|ref|ZP_07421216.2| transcriptional regulator [Mycobacterium tuberculosis SUMu003] gi|308371630|ref|ZP_07425585.2| transcriptional regulator [Mycobacterium tuberculosis SUMu004] 13 more sequence titles Length=213 Score = 422 bits (1086), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 205/206 (99%), Positives = 205/206 (99%), Gaps = 0/206 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR Sbjct 8 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 67 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA Sbjct 68 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 127 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 QYWSEICQIPISFI ETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ Sbjct 128 QYWSEICQIPISFIAETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 187 Query 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 PDDQACIQTLANIYYRAIYSKEDSSN Sbjct 188 PDDQACIQTLANIYYRAIYSKEDSSN 213 >gi|344218092|gb|AEM98722.1| transcriptional regulatory protein [Mycobacterium tuberculosis CTRI-2] Length=206 Score = 419 bits (1078), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 204/206 (99%), Positives = 205/206 (99%), Gaps = 0/206 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 +PDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR Sbjct 1 MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA Sbjct 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQF YLQLSGKRSRRGQ Sbjct 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFYYLQLSGKRSRRGQ 180 Query 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 PDDQACIQTLANIYYRAIYSKEDSSN Sbjct 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 >gi|289756340|ref|ZP_06515718.1| transcriptional regulatory protein [Mycobacterium tuberculosis EAS054] gi|289696927|gb|EFD64356.1| transcriptional regulatory protein [Mycobacterium tuberculosis EAS054] Length=206 Score = 419 bits (1078), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 204/206 (99%), Positives = 205/206 (99%), Gaps = 0/206 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 +PDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR Sbjct 1 MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA Sbjct 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRS RGQ Sbjct 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSCRGQ 180 Query 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 PDDQACIQTLANIYYRAIYSKEDSSN Sbjct 181 PDDQACIQTLANIYYRAIYSKEDSSN 206 >gi|118616911|ref|YP_905243.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] gi|118569021|gb|ABL03772.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] Length=202 Score = 337 bits (865), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 162/204 (80%), Positives = 181/204 (89%), Gaps = 2/204 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 +P+FPT RGR+TQAAID AARTV+ R GILATT+ADI AEAGRSAASFYNYYDSKEAMVR Sbjct 1 MPEFPTHRGRQTQAAIDTAARTVIARKGILATTIADIAAEAGRSAASFYNYYDSKEAMVR 60 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRD+ NQRALSV HGLS+RER+YEAAAAHW TYRNRLAE +SVSQLAMV++DFA Sbjct 61 QWALRFRDEVNQRALSVTSHGLSNRERSYEAAAAHWNTYRNRLAEMVSVSQLAMVNEDFA 120 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 Q +++C IPISFI ETVKRAQA GYC GDDPQL+AEAIVAMFNQFCY+QLSG R++ + Sbjct 121 QQCADMCAIPISFIKETVKRAQAEGYCPGDDPQLVAEAIVAMFNQFCYVQLSGSRTK--E 178 Query 181 PDDQACIQTLANIYYRAIYSKEDS 204 PDD ACIQTLANIYYRAIY E S Sbjct 179 PDDLACIQTLANIYYRAIYGVEVS 202 >gi|118463028|ref|YP_884008.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777328|ref|ZP_05218844.1| transcriptional regulator, TetR family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118164315|gb|ABK65212.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] Length=218 Score = 335 bits (858), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 160/200 (80%), Positives = 178/200 (89%), Gaps = 2/200 (1%) Query 4 FPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWA 63 PT RGRRT+AAID AARTV+ R G+LATT+ADI AEAGRSAASFYNYYDSKEAMVRQWA Sbjct 17 LPTHRGRRTRAAIDMAARTVIARKGVLATTIADIAAEAGRSAASFYNYYDSKEAMVRQWA 76 Query 64 LRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 LRFRD+ANQRA S RHGLSDR+RAY AAAAHW+TYRNRLAE ISVSQLAMV+DDFA+YW Sbjct 77 LRFRDEANQRARSATRHGLSDRDRAYTAAAAHWHTYRNRLAEVISVSQLAMVNDDFARYW 136 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +EIC IPISFI E+V+RAQA GYC DDPQL+AEAIVAMFNQFCY+QL RS G+PDD Sbjct 137 AEICAIPISFIAESVRRAQARGYCRDDDPQLIAEAIVAMFNQFCYIQLGSARS--GEPDD 194 Query 184 QACIQTLANIYYRAIYSKED 203 QACI+TLANIYYRAIY +E+ Sbjct 195 QACIRTLANIYYRAIYGREE 214 >gi|254820801|ref|ZP_05225802.1| hypothetical protein MintA_12783 [Mycobacterium intracellulare ATCC 13950] Length=215 Score = 334 bits (856), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 159/200 (80%), Positives = 179/200 (90%), Gaps = 3/200 (1%) Query 3 DFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQW 62 + PT RGRRTQAAID AARTV+ R G+LATT+ADI AEAGRSAASFYNYY+SKEAMVRQW Sbjct 16 ELPTHRGRRTQAAIDLAARTVIARKGVLATTIADIAAEAGRSAASFYNYYESKEAMVRQW 75 Query 63 ALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQY 122 ALRFRD+ANQRAL+V +HGL+DRERAY AAAAHW+TYRNRLAE ISVSQLAM++DDFAQY Sbjct 76 ALRFRDEANQRALAVTQHGLTDRERAYGAAAAHWHTYRNRLAEVISVSQLAMINDDFAQY 135 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPD 182 W+EIC IPISFI E+V+RAQA G C DDPQL+AEAIVAMFNQFCY+QL S RG+PD Sbjct 136 WAEICSIPISFIAESVRRAQAEGRCRDDDPQLIAEAIVAMFNQFCYIQLG---SARGEPD 192 Query 183 DQACIQTLANIYYRAIYSKE 202 D+ACIQTLANIYYRAIY+ E Sbjct 193 DEACIQTLANIYYRAIYATE 212 >gi|336460173|gb|EGO39078.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=216 Score = 334 bits (856), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 159/200 (80%), Positives = 178/200 (89%), Gaps = 2/200 (1%) Query 3 DFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQW 62 + PT RGRRTQAAID AARTV+ R G+LATT+ADI AEAGRSAASFYNYY+SKEAMVRQW Sbjct 16 ELPTHRGRRTQAAIDLAARTVIARKGVLATTIADIAAEAGRSAASFYNYYESKEAMVRQW 75 Query 63 ALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQY 122 ALRFRD+ANQRALSV +HGL+DRERAY AAAAHW+TYRNRLAE ISVSQLAM++DDFAQY Sbjct 76 ALRFRDEANQRALSVTQHGLTDRERAYGAAAAHWHTYRNRLAEVISVSQLAMINDDFAQY 135 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPD 182 W+EIC IPISFI E+V+RAQA G C DDPQL+AEAIVAMFNQFCY+QL R G+PD Sbjct 136 WAEICSIPISFIAESVRRAQAEGRCRDDDPQLIAEAIVAMFNQFCYVQLGSARC--GEPD 193 Query 183 DQACIQTLANIYYRAIYSKE 202 D+ACIQTLANIYYRAIY+ E Sbjct 194 DEACIQTLANIYYRAIYATE 213 >gi|41409816|ref|NP_962652.1| hypothetical protein MAP3718c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398648|gb|AAS06268.1| hypothetical protein MAP_3718c [Mycobacterium avium subsp. paratuberculosis K-10] Length=223 Score = 330 bits (847), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 157/200 (79%), Positives = 176/200 (88%), Gaps = 2/200 (1%) Query 3 DFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQW 62 + PT RGRRTQAAID AARTV+ R G+LA T+ADI AEAGRSAASFYNYY+SKEAMVRQW Sbjct 23 ELPTHRGRRTQAAIDLAARTVIARKGVLAATIADIAAEAGRSAASFYNYYESKEAMVRQW 82 Query 63 ALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQY 122 ALRFRD+ANQRALSV +HGL+DRERAY AAAAHW+TYRNRLAE ISVSQL M++DDFAQY Sbjct 83 ALRFRDEANQRALSVTQHGLTDRERAYGAAAAHWHTYRNRLAEVISVSQLTMINDDFAQY 142 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPD 182 W+EIC IPISFI E+V+RAQA G C DDPQL+AEAIVAMFNQFCY+QL R G+PD Sbjct 143 WAEICSIPISFIAESVRRAQAEGRCRDDDPQLIAEAIVAMFNQFCYVQLGSARC--GEPD 200 Query 183 DQACIQTLANIYYRAIYSKE 202 D+ACIQTLANIYYRAIY+ E Sbjct 201 DEACIQTLANIYYRAIYATE 220 >gi|183980561|ref|YP_001848852.1| transcriptional regulatory protein [Mycobacterium marinum M] gi|183173887|gb|ACC38997.1| transcriptional regulatory protein [Mycobacterium marinum M] Length=202 Score = 322 bits (826), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 164/204 (81%), Positives = 182/204 (90%), Gaps = 2/204 (0%) Query 1 VPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR 60 +P+FPT RGR+TQAAID AARTV+ R GILATT+ADI AEAGRSAASFYNYYDSKEAMVR Sbjct 1 MPEFPTHRGRQTQAAIDTAARTVIARKGILATTIADIAAEAGRSAASFYNYYDSKEAMVR 60 Query 61 QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA 120 QWALRFRD+ NQRALSV HGLS+RERAYEAAAAHW TYRNRLAE +SVSQLAMV++DFA Sbjct 61 QWALRFRDEVNQRALSVTSHGLSNRERAYEAAAAHWNTYRNRLAEMVSVSQLAMVNEDFA 120 Query 121 QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ 180 Q W+++C IPISFI ETVKRAQA GYC GDDPQL+AEAIVAMFNQFCY+QLSG R++ + Sbjct 121 QQWADMCAIPISFIKETVKRAQAEGYCPGDDPQLVAEAIVAMFNQFCYIQLSGSRTK--E 178 Query 181 PDDQACIQTLANIYYRAIYSKEDS 204 PDD ACIQTLANIYYRAIY E S Sbjct 179 PDDLACIQTLANIYYRAIYGVEVS 202 >gi|342859255|ref|ZP_08715909.1| hypothetical protein MCOL_10263 [Mycobacterium colombiense CECT 3035] gi|342133496|gb|EGT86699.1| hypothetical protein MCOL_10263 [Mycobacterium colombiense CECT 3035] Length=211 Score = 322 bits (825), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 158/198 (80%), Positives = 180/198 (91%), Gaps = 2/198 (1%) Query 3 DFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQW 62 + PT RGRRTQAAID AARTV+ R G+LATT+ADI AEAGRSAASFYNYY+SKEAMVRQW Sbjct 16 ELPTVRGRRTQAAIDLAARTVIARKGVLATTIADIAAEAGRSAASFYNYYESKEAMVRQW 75 Query 63 ALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQY 122 ALRFRD+AN+RALSV HGLSDRERA+ AAAAHW+TYR+RLAE ISVSQLAM++DDFAQY Sbjct 76 ALRFRDEANERALSVTEHGLSDRERAHAAAAAHWHTYRHRLAEVISVSQLAMINDDFAQY 135 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPD 182 W+EIC+IPISFI E+V+RAQA G+C GDDP+L+AEAIVAMFNQFCY+QL G R+ QPD Sbjct 136 WAEICEIPISFIAESVRRAQAEGHCRGDDPRLIAEAIVAMFNQFCYVQLGGARA--SQPD 193 Query 183 DQACIQTLANIYYRAIYS 200 DQACIQTLANIYYRAIY+ Sbjct 194 DQACIQTLANIYYRAIYA 211 >gi|240168492|ref|ZP_04747151.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=202 Score = 320 bits (820), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 165/199 (83%), Positives = 179/199 (90%), Gaps = 2/199 (1%) Query 4 FPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWA 63 FPT RGRRT AAID AARTV+ R GILATTVADI AEAGRS ASFYNYYDSKEAMVRQWA Sbjct 4 FPTHRGRRTHAAIDTAARTVIARKGILATTVADIAAEAGRSTASFYNYYDSKEAMVRQWA 63 Query 64 LRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 L FRD+AN+RA SV RHGLS+RERAYEAAAAHW TYRNRLAE ISVSQLAMV+DDFAQYW Sbjct 64 LGFRDEANERAQSVTRHGLSNRERAYEAAAAHWQTYRNRLAEMISVSQLAMVNDDFAQYW 123 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 SEIC IP+SFITETV+RAQ+ G+C DDPQL+AEAIVAMFNQFCYLQLSG R+R +PDD Sbjct 124 SEICAIPLSFITETVQRAQSQGFCPDDDPQLVAEAIVAMFNQFCYLQLSGARAR--EPDD 181 Query 184 QACIQTLANIYYRAIYSKE 202 QACI+TLANIYYRAIY +E Sbjct 182 QACIRTLANIYYRAIYGEE 200 >gi|333988902|ref|YP_004521516.1| transcriptional regulator [Mycobacterium sp. JDM601] gi|333484870|gb|AEF34262.1| transcriptional regulatory protein [Mycobacterium sp. JDM601] Length=214 Score = 313 bits (801), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 143/201 (72%), Positives = 172/201 (86%), Gaps = 0/201 (0%) Query 4 FPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWA 63 PT+RGRRTQAAID+AAR V+ R G+LATT+ADI AEAGRSAASFYNYYDSKEAMVR+WA Sbjct 14 LPTRRGRRTQAAIDSAARAVIARKGVLATTIADIAAEAGRSAASFYNYYDSKEAMVREWA 73 Query 64 LRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 LRFRD+A +R +RHGLS+RER +AAAAHWYTYRNRLAE + VSQLAMV+DDFA+YW Sbjct 74 LRFRDEAGERVSGAVRHGLSNRERIEQAAAAHWYTYRNRLAEMVGVSQLAMVNDDFARYW 133 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +EIC +P++FITETVKRAQA G+C DDP+L+A AIV+M NQFCY+QL+ R PDD Sbjct 134 AEICAVPVAFITETVKRAQADGHCADDDPELLAVAIVSMLNQFCYVQLAAPRRGGAAPDD 193 Query 184 QACIQTLANIYYRAIYSKEDS 204 ACI+TLAN++YRAIY++E S Sbjct 194 DACIRTLANVFYRAIYTEEGS 214 >gi|120401431|ref|YP_951260.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954249|gb|ABM11254.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=212 Score = 277 bits (708), Expect = 8e-73, Method: Compositional matrix adjust. Identities = 133/202 (66%), Positives = 163/202 (81%), Gaps = 1/202 (0%) Query 3 DFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQW 62 + PT RGR+TQAAID AAR+V+ R GILATTVADI EAGRS ASFYNYYDSKEAMVR+W Sbjct 8 ELPTVRGRQTQAAIDMAARSVIARKGILATTVADIAGEAGRSTASFYNYYDSKEAMVREW 67 Query 63 ALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQY 122 A+RFRD+A R+LS R GLS+ ER+Y+AAAAHW TYRNRLAE I+VSQ+AM+SDDFA+Y Sbjct 68 AVRFRDEARTRSLSAARPGLSNWERSYQAAAAHWNTYRNRLAEIIAVSQMAMISDDFAEY 127 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSR-RGQP 181 W+EIC +PI+ IT VK+AQ G+C DD +L+A A+V+M NQFCY QLSG + Sbjct 128 WNEICSLPIALITSLVKQAQREGFCPEDDARLVAVALVSMLNQFCYTQLSGVNADASADI 187 Query 182 DDQACIQTLANIYYRAIYSKED 203 DD+ACI+TLA+I+YR IY E+ Sbjct 188 DDEACIKTLADIFYRTIYYPEN 209 >gi|289764392|ref|ZP_06523770.1| predicted protein [Mycobacterium tuberculosis GM 1503] gi|289711898|gb|EFD75914.1| predicted protein [Mycobacterium tuberculosis GM 1503] Length=160 Score = 270 bits (690), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 139/142 (98%), Positives = 139/142 (98%), Gaps = 0/142 (0%) Query 65 RFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 R D ANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS Sbjct 19 RLVDHANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 78 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQ 184 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQ Sbjct 79 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQ 138 Query 185 ACIQTLANIYYRAIYSKEDSSN 206 ACIQTLANIYYRAIYSKEDSSN Sbjct 139 ACIQTLANIYYRAIYSKEDSSN 160 >gi|169631409|ref|YP_001705058.1| transcriptional regulator TetR [Mycobacterium abscessus ATCC 19977] gi|169243376|emb|CAM64404.1| Possible transcriptional regulatory protein TetR [Mycobacterium abscessus] Length=201 Score = 260 bits (665), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 128/198 (65%), Positives = 154/198 (78%), Gaps = 2/198 (1%) Query 5 PTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWAL 64 PT RGR+TQAAID AARTV+ R GIL+TTVADI AEAGRS ASFYNYYDSKEAMV QWA+ Sbjct 4 PTVRGRQTQAAIDEAARTVIARKGILSTTVADIAAEAGRSTASFYNYYDSKEAMVAQWAM 63 Query 65 RFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 RFR +A +R + IRHG S+++RA + A AHW T+R++LAE ISVSQLAM++ +FA++W+ Sbjct 64 RFRTEAQERVSAAIRHGRSNKQRARDIATAHWLTWRHQLAEMISVSQLAMINTEFAEFWN 123 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQ 184 ++C PI F+T T+KRAQ GY G+DP LMA AIV+M NQF Y QLS S DD Sbjct 124 QMCSEPIDFLTTTIKRAQRDGYSPGNDPHLMASAIVSMMNQFAYNQLSQGNS--ATVDDD 181 Query 185 ACIQTLANIYYRAIYSKE 202 ACI TLA I YRAIYSKE Sbjct 182 ACIDTLAGICYRAIYSKE 199 >gi|118470523|ref|YP_885017.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118171810|gb|ABK72706.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=209 Score = 254 bits (650), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 130/198 (66%), Positives = 155/198 (79%), Gaps = 2/198 (1%) Query 4 FPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWA 63 PT RGR+TQAAIDAAAR V+ R GILATT+ADI AEA RS ASFYNYYDSKEAMV +WA Sbjct 9 LPTARGRQTQAAIDAAARAVISRKGILATTIADIAAEANRSTASFYNYYDSKEAMVHEWA 68 Query 64 LRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 LRFRD+A RA + GL++ ER+Y+A +AHW TYR+RLAE ISVSQLAMVSDDFAQYW Sbjct 69 LRFRDEARDRAQAAREPGLTNWERSYQAVSAHWATYRHRLAEIISVSQLAMVSDDFAQYW 128 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +EIC++PIS IT+ +K AQ G+C DDP L A A+V+M NQFCY +LSG + DD Sbjct 129 AEICELPISLITDMIKHAQRQGFCPDDDPHLTAVALVSMLNQFCYTKLSGGNA--DDVDD 186 Query 184 QACIQTLANIYYRAIYSK 201 ACI TLAN++YR IY + Sbjct 187 TACITTLANVFYRTIYHR 204 >gi|304310725|ref|YP_003810323.1| Transcriptional regulator [gamma proteobacterium HdN1] gi|301796458|emb|CBL44666.1| Transcriptional regulator [gamma proteobacterium HdN1] Length=217 Score = 195 bits (495), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 100/202 (50%), Positives = 132/202 (66%), Gaps = 1/202 (0%) Query 5 PTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWAL 64 PT+RGR T AAIDAAAR ++ G L +VADI AE+GRSAASFYNYY+S+E M+ +WA Sbjct 10 PTRRGRETLAAIDAAARKLIAEKGFLNVSVADIAAESGRSAASFYNYYESREHMLARWAE 69 Query 65 RFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 RFRD A +RA L+ RE+ Y A AH TYR LAE I V QLAM+S DFA+YW Sbjct 70 RFRDKARRRAHEAFDPRLTHREQIYREARAHVTTYRESLAEMIGVFQLAMISKDFARYWR 129 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQ 184 E+CQ + IT ++ AQ GYC G P + A AIV++ NQ+CY S +D+ Sbjct 130 ELCQPAVDLITTMIQSAQREGYCRGMHPVMAATAIVSLLNQYCYEHYSTN-GLLEDAEDE 188 Query 185 ACIQTLANIYYRAIYSKEDSSN 206 A I+ +A+++Y AIY ++D + Sbjct 189 AVIRVIADLWYHAIYWQDDPDD 210 >gi|326384397|ref|ZP_08206078.1| transcriptional regulator TetR [Gordonia neofelifaecis NRRL B-59395] gi|326196995|gb|EGD54188.1| transcriptional regulator TetR [Gordonia neofelifaecis NRRL B-59395] Length=205 Score = 192 bits (487), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 103/198 (53%), Positives = 132/198 (67%), Gaps = 3/198 (1%) Query 5 PTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWAL 64 PT+RGR TQ AIDAAAR V+ G L TVADI EAG+S ASFYNYYDSKEA++ WA Sbjct 11 PTRRGRATQDAIDAAARKVIAEKGFLKMTVADIVKEAGKSPASFYNYYDSKEALMESWAR 70 Query 65 RFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 +F+ +A RA + R G + R R AA AHW TYR+ LAE + V QLAM++DDFAQ W Sbjct 71 QFQLEARTRAAAYERSGTT-RARVEAAARAHWETYRDHLAEMVGVYQLAMINDDFAQVWD 129 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQ 184 E+ + + I++ + AQ GYC G D +L+A AIVAM QFCY L+ R+ DD+ Sbjct 130 EVSREAVDGISQGIVLAQKKGYCPGHDAELVARAIVAMMQQFCYDNLAAGRAETA--DDE 187 Query 185 ACIQTLANIYYRAIYSKE 202 ACI TL I+YR+++ E Sbjct 188 ACIATLTEIWYRSVFWTE 205 >gi|333988724|ref|YP_004521338.1| transcriptional regulator [Mycobacterium sp. JDM601] gi|333484692|gb|AEF34084.1| transcriptional regulatory protein [Mycobacterium sp. JDM601] Length=214 Score = 166 bits (421), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 87/202 (44%), Positives = 123/202 (61%), Gaps = 1/202 (0%) Query 5 PTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWAL 64 PT RGR TQA ++ AAR V+ R G TT+ DIT+ A RS ASFY+Y++SKE ++ A Sbjct 13 PTVRGRDTQARLEQAAREVIARKGFFKTTITDITSAAKRSPASFYHYFESKEDLLASLAE 72 Query 65 RFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 FR A RA+ + G R+ E+ AHW TYR+ L + V QLAM++D+FAQ W Sbjct 73 DFRALAKSRAVQALHPGQDLRDIIEESVRAHWETYRDHLGVMVGVFQLAMINDEFAQRWR 132 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQP-DD 183 ++C I ++ +TV+ AQ GY DP+L+ AIVAM N F Y+ L G+ DD Sbjct 133 DMCADAIDWVAQTVRMAQRKGYGTDADPELVGSAIVAMLNHFTYVWLVAGGDVAGRELDD 192 Query 184 QACIQTLANIYYRAIYSKEDSS 205 +A I+TL + +YR++ +E S Sbjct 193 EAAIKTLTDTWYRSVSWREQGS 214 >gi|296269494|ref|YP_003652126.1| TetR family transcriptional regulator [Thermobispora bispora DSM 43833] gi|296092281|gb|ADG88233.1| transcriptional regulator, TetR family [Thermobispora bispora DSM 43833] Length=218 Score = 132 bits (332), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 75/195 (39%), Positives = 108/195 (56%), Gaps = 7/195 (3%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GRRT+AA+ AAR V G L ++DIT AG+S+ SFY YYD KE ++ R Sbjct 25 TPKGRRTEAALLDAARRVFAEKGFLNAKISDITRAAGKSSGSFYTYYDGKEELLTALLDR 84 Query 66 FRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSE 125 A A H RE A A+W TYR L E + + QL+M FA+ W E Sbjct 85 L-PPAEPPA-----HTGDPREAVRSAVRAYWTTYRAHLGEMVGLFQLSMTDPAFAERWRE 138 Query 126 ICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQL-SGKRSRRGQPDDQ 184 + I + E ++ A+A G+ + DP ++A AIV+M FC++ L +G + PDD+ Sbjct 139 LRAARIRTVLEVIRDAEASGHRLDLDPGILASAIVSMLESFCWVWLAAGGDAGVAPPDDE 198 Query 185 ACIQTLANIYYRAIY 199 I+TL+ I+YRA+Y Sbjct 199 TAIETLSAIWYRALY 213 >gi|169627418|ref|YP_001701067.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169239385|emb|CAM60413.1| Possible transcriptional regulator, TetR family [Mycobacterium abscessus] Length=194 Score = 119 bits (299), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 70/190 (37%), Positives = 95/190 (50%), Gaps = 3/190 (1%) Query 19 AARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVI 78 AAR V+ R G T V DIT EAG+S FYNY+ K ++R FRDDA R +V Sbjct 3 AARVVISRVGYAETRVIDITTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYARGDTVA 62 Query 79 RHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETV 138 E + +W TYR V Q A V F YW + + I + Sbjct 63 TSDRPPHEVIRDIVTVYWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPARTMIANNI 122 Query 139 KRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQL--SGKRSRRGQPDDQACIQTLANIYYR 196 + QA GYC G DP + A AI AM + FCY+ L G+R R D++A I TLA I++ Sbjct 123 RHLQARGYCPGMDPDITASAIGAMLDYFCYVWLVEGGERGRSAVTDEEA-IDTLARIWFN 181 Query 197 AIYSKEDSSN 206 A++ K + ++ Sbjct 182 ALWWKSEGAH 191 >gi|269125208|ref|YP_003298578.1| TetR family transcriptional regulator [Thermomonospora curvata DSM 43183] gi|268310166|gb|ACY96540.1| transcriptional regulator, TetR family [Thermomonospora curvata DSM 43183] Length=213 Score = 119 bits (297), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 71/202 (36%), Positives = 102/202 (51%), Gaps = 4/202 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GRRT+AA AAR G T ++DI A AGRS SFYNYYD+KE ++ Sbjct 14 TPKGRRTEAAFLEAARRTFAEKGYFNTKISDIAAAAGRSPGSFYNYYDNKEQLLEALLEE 73 Query 66 FRDDANQRALSVIRHGLSDRERAYEAA-AAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 F + S + G D AA A+W+TYR L E I + Q++M + F Q W Sbjct 74 FAQEV--MTASTLESGSGDPYEGVRAAVTAYWHTYRKYLPEMIGLFQMSMTDERFRQRWR 131 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQL-SGKRSRRGQPDD 183 E I + + A+ G+ +G D +A A+V++ FC+ L +G + PDD Sbjct 132 EHRAAGIRGVLRGLHAAERSGHTIGLDLPTLASALVSLLESFCWTWLGAGGEADVAPPDD 191 Query 184 QACIQTLANIYYRAIYSKEDSS 205 + I TL I+YR +Y S+ Sbjct 192 ETAITTLTEIWYRTVYGAAPSA 213 >gi|343928644|ref|ZP_08768089.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343761393|dbj|GAA15015.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=204 Score = 110 bits (275), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 69/197 (36%), Positives = 102/197 (52%), Gaps = 5/197 (2%) Query 5 PTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWAL 64 PT +GR+T+AA AAR G L T ++DI AGRS SFYNYYD+K+ ++ Sbjct 3 PTNKGRQTEAAFLDAARRCFADKGYLNTKISDIAEAAGRSTGSFYNYYDNKDQLLEALLD 62 Query 65 RFRDDANQRALSVIRHGLSDRERAYEAA-AAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 +F D+ + +L+ RH SD E AA A+W TY+ L E I + Q++M+ D+F W Sbjct 63 QFSDEVVEGSLAT-RH--SDPEAGVRAAVTAYWTTYKKYLPEIIGLFQMSMLDDEFRDRW 119 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ-PD 182 I + + A+ GY VG + +A A+V C+ L+ + G PD Sbjct 120 HANRASGIKQVLAGLHSAERAGYDVGLPLEPLASALVNTLESSCWSWLAVRGGVVGSIPD 179 Query 183 DQACIQTLANIYYRAIY 199 D I L I++R +Y Sbjct 180 DDTAIDILTTIWFRTVY 196 >gi|262203327|ref|YP_003274535.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262086674|gb|ACY22642.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=199 Score = 109 bits (272), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 73/204 (36%), Positives = 100/204 (50%), Gaps = 15/204 (7%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GRRT+AA AAR V G L ++DI A AGRSA SFYNYYD+K+ ++ Sbjct 4 TPKGRRTEAAFHQAARQVFAEKGFLNAKISDIAAVAGRSAGSFYNYYDNKQQLLEALLET 63 Query 66 FRDDANQRALSVIRHGLSDRERAYEAAAAHWY--TYRNRLAEAISVSQLAMVSDDFAQYW 123 F D L R L+ R AA Y YR L E I V QL+M + FA +W Sbjct 64 FNTD----VLEGTRERLTTDPRQNVEAAVRVYFEMYRKYLPEMIGVFQLSMTDEQFAAWW 119 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQP-- 181 + I + + V+ + G V D + A AIV+M FC+ + G P Sbjct 120 RQRRADGIDAVLKVVRSVEKQGVAVDLDHGVFASAIVSMMESFCWTWYAAG----GDPGI 175 Query 182 ---DDQACIQTLANIYYRAIYSKE 202 DD+ I TL+ I+ RA+Y+ + Sbjct 176 DTHDDEVAIATLSEIFRRAMYNGQ 199 >gi|296169199|ref|ZP_06850852.1| transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896097|gb|EFG75764.1| transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=204 Score = 102 bits (255), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 64/201 (32%), Positives = 100/201 (50%), Gaps = 3/201 (1%) Query 2 PDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQ 61 PD T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+D KE ++ Sbjct 4 PDALTAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFDDKEDLLAA 63 Query 62 WALRFRDDANQRALSVIRHGLSDRERAY--EAAAAHWYTYRNRLAEAISVSQLAMVSDDF 119 A F D + + +S + A+ +W ++ + I+V+QLA F Sbjct 64 LAESFLHDVVTPSGLSLEPPVSPDDDAFFTSVVTGYWNMFKQNIGIMIAVAQLAATQRRF 123 Query 120 AQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRG 179 A +E + + + +V+RAQ GY DPQ A AI +F F + G + Sbjct 124 AAVQNEFRRFGMDIVAASVRRAQEQGYATELDPQHTAAAIALLFENFTTV-FVGPSNLGL 182 Query 180 QPDDQACIQTLANIYYRAIYS 200 + D+ I TLA I+ + +Y Sbjct 183 KISDEDAIATLATIWKKTLYG 203 >gi|288922539|ref|ZP_06416721.1| transcriptional regulator, TetR family [Frankia sp. EUN1f] gi|288346128|gb|EFC80475.1| transcriptional regulator, TetR family [Frankia sp. EUN1f] Length=206 Score = 100 bits (250), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 61/202 (31%), Positives = 103/202 (51%), Gaps = 3/202 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T++G+RT+AA AAR V G + DI A RS+ASFYNYY++KE ++ Sbjct 4 TRKGQRTEAAFLDAARQVFAEKGYFNAKINDIAQAANRSSASFYNYYENKEEILDALLGE 63 Query 66 FRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSE 125 F + A + G + + A+W++YR LAE I + Q++M + Q W E Sbjct 64 FSHEI--VAGAQFGKGADPLDTIRGSVQAYWHSYRKYLAEMIGLFQMSMTDPAYTQRWRE 121 Query 126 ICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQL-SGKRSRRGQPDDQ 184 I + K + G+ + D +A A+V+M FC+ L +G + PDD+ Sbjct 122 NRAAGIQGVIAVNKAVEKAGHPIRLDHATLASALVSMLEAFCWTWLVAGGEAGVAAPDDE 181 Query 185 ACIQTLANIYYRAIYSKEDSSN 206 I+TL+ ++YR ++ ++++ Sbjct 182 TAIETLSAMWYRTVFFHSENAS 203 >gi|271961895|ref|YP_003336091.1| TetR family transcriptional regulator [Streptosporangium roseum DSM 43021] gi|270505070|gb|ACZ83348.1| putative transcriptional regulator, TetR family [Streptosporangium roseum DSM 43021] Length=211 Score = 98.2 bits (243), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 67/196 (35%), Positives = 101/196 (52%), Gaps = 14/196 (7%) Query 11 RTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDA 70 +T+ A+ AAR V RNG L T + DITAEAGRSA SFY ++ SKE +++ + A Sbjct 17 QTEVALKEAARRVFARNGYLNTKITDITAEAGRSAGSFYKHFASKEEVLQALLADWFAQA 76 Query 71 NQRALSVIRHG--LSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQ 128 + LS G LS A +W+TYR L E ++ Q A+V +FA+ ++I Sbjct 77 GEE-LSTHEAGDDLSKEPALRARVATYWHTYRAHLPEIHALGQAALVDPEFAERVAQIRH 135 Query 129 IPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQP------D 182 + + E ++R QA G+ + DP ++A A A+ FC + G G+P D Sbjct 136 AQLQTMREHLQRLQAAGFDLPGDPAVLASAFNALLEGFCAVWAGGG----GEPIGRVLGD 191 Query 183 DQACIQTLANIYYRAI 198 D+A I TL + + Sbjct 192 DEA-IDTLTGLLRHGL 206 >gi|118470247|ref|YP_886432.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118171534|gb|ABK72430.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=203 Score = 97.8 bits (242), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 60/195 (31%), Positives = 97/195 (50%), Gaps = 3/195 (1%) Query 8 RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFR 67 +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A F Sbjct 9 KGRQTRTAIELAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFTDKEDLLAALAESFL 68 Query 68 DDANQ-RALSV-IRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSE 125 D + L++ + D E +W ++ + I+V+QLA FA+ + Sbjct 69 HDVVEPSGLNLHLPDSPDDAEFFTSVVTGYWNMFKQNIGIMIAVAQLAATQQRFAEVQNS 128 Query 126 ICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQA 185 + I + +V+RAQ G+ VG P+ + AI +F F + G + DD+ Sbjct 129 FRRFGIDIVVASVRRAQEQGHAVGLVPEHIGAAIALLFENFTTV-FVGSSGLGVELDDRE 187 Query 186 CIQTLANIYYRAIYS 200 I TLA I+ + +Y Sbjct 188 AITTLATIWKKTLYG 202 >gi|240168590|ref|ZP_04747249.1| hypothetical protein MkanA1_04715 [Mycobacterium kansasii ATCC 12478] Length=206 Score = 96.7 bits (239), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 63/199 (32%), Positives = 99/199 (50%), Gaps = 4/199 (2%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A Sbjct 7 TAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFSDKEDLLAALAES 66 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F D LSV D + + + +W ++ + I+V+QLA FA Sbjct 67 FLHDVVAPSGLSVHLPDTPDDDTFFTSVVTGYWNIFKQNIGIMIAVAQLAATQRRFAAVQ 126 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQF--CYLQLSGKRSRRGQP 181 +E + + + +V+RAQ GY PQ A AI +F F ++ SG + R Sbjct 127 NEFRRFGMDIVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTVFVGRSGPENLRLDI 186 Query 182 DDQACIQTLANIYYRAIYS 200 D+ I+TL+ I+ + +Y Sbjct 187 SDEDAIKTLSMIWKKTLYG 205 >gi|333991495|ref|YP_004524109.1| transcriptional regulator [Mycobacterium sp. JDM601] gi|333487463|gb|AEF36855.1| transcriptional regulatory protein [Mycobacterium sp. JDM601] Length=204 Score = 93.2 bits (230), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 60/198 (31%), Positives = 98/198 (50%), Gaps = 3/198 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 + +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A Y Y+ KE ++ A Sbjct 8 SSKGRQTRQAIEQAARELFAERGFHGTTLADITSAAGKSTAVLYRYFQDKEDLLAALAES 67 Query 66 FRDDANQRALSVIRHGLS--DRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F D + + +R S D E A+W ++ + I+V+QLA S FA Sbjct 68 FLSDVVEPSRLKMRLPDSPQDTEFFTSVVGAYWSMFKQNIGIMIAVAQLAATSQRFAVLQ 127 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +E + + + +V+RAQ G+ + DP +A AI +F F + G + D Sbjct 128 NEFRRFGMEIVAASVRRAQQQGHGLDLDPDHIAAAIALLFENFTVV-FVGPSGPGWRISD 186 Query 184 QACIQTLANIYYRAIYSK 201 I TL+ I+ + +Y + Sbjct 187 SDAIATLSTIWRKTLYGR 204 >gi|118462296|ref|YP_883179.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|118163583|gb|ABK64480.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] Length=203 Score = 93.2 bits (230), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 62/197 (32%), Positives = 95/197 (49%), Gaps = 3/197 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A Sbjct 7 TAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFADKEDLLAALAES 66 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F + LSV D + + A +W ++ + I+V+QLA FA Sbjct 67 FLHEVVTPSGLSVHLPDSPDDDAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQ 126 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +E + I + +V+RAQ GY PQ A AI +F F + G + D Sbjct 127 NEFRRFGIDLVAASVRRAQEQGYGTELHPQHTAAAIALLFENFTTV-FVGPSGLGIEISD 185 Query 184 QACIQTLANIYYRAIYS 200 + I TL+ I+ + +Y Sbjct 186 EDAIATLSTIWKKTLYG 202 >gi|336459353|gb|EGO38296.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=203 Score = 93.2 bits (230), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 62/197 (32%), Positives = 95/197 (49%), Gaps = 3/197 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A Sbjct 7 TAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFADKEDLLAALAES 66 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F + LSV D + + A +W ++ + I+V+QLA FA Sbjct 67 FLHEVVTPSGLSVHLPDSPDDDAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQ 126 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +E + I + +V+RAQ GY PQ A AI +F F + G + D Sbjct 127 NEFRRFGIDLVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTV-FVGPSGLGIEISD 185 Query 184 QACIQTLANIYYRAIYS 200 + I TL+ I+ + +Y Sbjct 186 EDAIATLSTIWKKTLYG 202 >gi|41409293|ref|NP_962129.1| hypothetical protein MAP3195 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398113|gb|AAS05743.1| hypothetical protein MAP_3195 [Mycobacterium avium subsp. paratuberculosis K-10] Length=209 Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 62/197 (32%), Positives = 95/197 (49%), Gaps = 3/197 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A Sbjct 13 TAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFADKEDLLAALAES 72 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F + LSV D + + A +W ++ + I+V+QLA FA Sbjct 73 FLHEVVTPSGLSVHLPDSPDDDAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQ 132 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +E + I + +V+RAQ GY PQ A AI +F F + G + D Sbjct 133 NEFRRFGIDLVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTV-FVGPSGLGIEISD 191 Query 184 QACIQTLANIYYRAIYS 200 + I TL+ I+ + +Y Sbjct 192 EDAIATLSTIWKKTLYG 208 >gi|254821128|ref|ZP_05226129.1| hypothetical protein MintA_14422 [Mycobacterium intracellulare ATCC 13950] Length=207 Score = 92.4 bits (228), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 59/197 (30%), Positives = 98/197 (50%), Gaps = 3/197 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TTVADIT+ AG+S A FY Y+ KE ++ A Sbjct 11 TAKGRQTRQAIEQAARKLFAERGFHGTTVADITSAAGKSPAVFYRYFTDKEDLLAALAKS 70 Query 66 FRDDANQRALSVIRHGLSDRERAY--EAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F + + + + + + A+ +W ++ + I+V+QLA FA Sbjct 71 FLHEVVTPSGASVHLPDAPDDDAFFTSVVTGYWNMFKQNIGIMIAVAQLAATQRRFAAVQ 130 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +E ++ I + +V+RAQ GY +P+ A AI +F F + G + + D Sbjct 131 NEFRRLGIDLVAASVRRAQEQGYGAELNPEHTAAAIALLFENFTTV-FVGPSNLGIKISD 189 Query 184 QACIQTLANIYYRAIYS 200 + I TL+ I+ R +Y Sbjct 190 KDAIATLSTIWKRTLYG 206 >gi|254776448|ref|ZP_05217964.1| hypothetical protein MaviaA2_17514 [Mycobacterium avium subsp. avium ATCC 25291] Length=203 Score = 91.3 bits (225), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 62/197 (32%), Positives = 94/197 (48%), Gaps = 3/197 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A Sbjct 7 TAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFADKEDLLAALAES 66 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F + LSV D + + A +W ++ + I+V+QLA FA Sbjct 67 FLHEVVTPSGLSVHLPDSPDDDAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQ 126 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 +E + I + +V+RAQ GY PQ A AI +F F + G + D Sbjct 127 NEFRRFGIDLVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTV-FVGPSGLGIEISD 185 Query 184 QACIQTLANIYYRAIYS 200 + I TL+ I+ + Y Sbjct 186 EDAIATLSTIWKKTPYG 202 >gi|342861045|ref|ZP_08717694.1| hypothetical protein MCOL_19277 [Mycobacterium colombiense CECT 3035] gi|342131489|gb|EGT84759.1| hypothetical protein MCOL_19277 [Mycobacterium colombiense CECT 3035] Length=214 Score = 91.3 bits (225), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 61/199 (31%), Positives = 96/199 (49%), Gaps = 4/199 (2%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+ KE ++ A Sbjct 11 TAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFTDKEDLLAALAES 70 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEA-AAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F + LSV D + + + +W ++ + I+V+QLA FA Sbjct 71 FLHEVVTPSGLSVHLPESPDDDAFFTSVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQ 130 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQF--CYLQLSGKRSRRGQP 181 +E + + + +V+RAQ GY PQ A AI +F F ++ SG Sbjct 131 NEFRRFGMDLVAASVRRAQDQGYGAELHPQHTAAAIALLFENFTTVFVGPSGPVGLGVDI 190 Query 182 DDQACIQTLANIYYRAIYS 200 D+ I TL+ I+ + +Y Sbjct 191 GDEDAIATLSTIWKKTLYG 209 >gi|315445415|ref|YP_004078294.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315263718|gb|ADU00460.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=206 Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 61/206 (30%), Positives = 99/206 (49%), Gaps = 7/206 (3%) Query 1 VPDFPTQ----RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKE 56 +P P++ +GR+T+ A+ AAR + G TT+ADIT+ AG+S A+FY Y++ KE Sbjct 1 MPPGPSETLSAKGRQTRDALAQAARKLFAERGFHGTTLADITSAAGKSPAAFYRYFNDKE 60 Query 57 AMVRQWALRFRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAM 114 ++ A F D L V D + + A +W ++ + I+V+QLA Sbjct 61 DLLAALAESFLHDVVAPSGLRVPLPESPDDDAFFTAVVTGYWTMFKQNIGIMIAVAQLAA 120 Query 115 VSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGK 174 F +E + + + +V+RAQ GY +P+ A AI +F F + G Sbjct 121 TQPRFTLVQNEFRRFGMDIVAASVRRAQEQGYGTELNPEHTAAAIALLFENFTTV-FVGA 179 Query 175 RSRRGQPDDQACIQTLANIYYRAIYS 200 Q DQ I TL+ I+ + +Y Sbjct 180 SGLGVQMTDQDAIATLSRIWKKTLYG 205 >gi|145225046|ref|YP_001135724.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145217532|gb|ABP46936.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=206 Score = 87.8 bits (216), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 58/195 (30%), Positives = 94/195 (49%), Gaps = 3/195 (1%) Query 8 RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFR 67 +GR+T+ A+ AAR + G TT++DIT+ AG+S A+FY Y+ KE ++ A F Sbjct 12 KGRQTRDALAQAARKLFAERGFHGTTLSDITSAAGKSPAAFYRYFSDKEDLLAALAESFL 71 Query 68 DD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYWSE 125 + LSV D + + A +W ++ + I+V+QLA F +E Sbjct 72 HEVVAPSGLSVPLPESPDDDAFFTAVVTGYWTMFKQNIGIMIAVAQLAATQPRFTLVQNE 131 Query 126 ICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQA 185 + + + +V+RAQ GY +P+ A AI +F F + G Q DQ Sbjct 132 FRRFGMDIVAASVRRAQEQGYGTELNPEHTAAAIALLFENFTTV-FVGASGLGVQMTDQD 190 Query 186 CIQTLANIYYRAIYS 200 I TL+ I+ + +Y Sbjct 191 AIATLSRIWKKTLYG 205 >gi|120402891|ref|YP_952720.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119955709|gb|ABM12714.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=206 Score = 86.3 bits (212), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 59/195 (31%), Positives = 93/195 (48%), Gaps = 3/195 (1%) Query 8 RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFR 67 +GR+T+ AI+ AAR + G TT+ DIT+ AG+S A FY Y+ KE ++ A F Sbjct 12 KGRQTRDAIEQAARKLFAERGFHGTTLGDITSAAGKSPAVFYRYFADKEDLLAALAESFL 71 Query 68 DD-ANQRALSVIRHGLSDRERAYE-AAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSE 125 D LSV D + + +W ++ + I+V+QLA FA +E Sbjct 72 HDVVAPSGLSVPLPESPDDDAFFTMVVTGYWTMFKQNIGIMIAVAQLAATQSRFALVQNE 131 Query 126 ICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQA 185 + + + +V+RAQ GY + + A AI +F F + G DD+A Sbjct 132 FRRFGMDIVAASVRRAQEQGYGRELNAEHTAAAIALLFENFTTV-FVGASGLDVDIDDEA 190 Query 186 CIQTLANIYYRAIYS 200 I TL+ I+ + +Y Sbjct 191 AIATLSRIWKKTLYG 205 >gi|108798557|ref|YP_638754.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119867656|ref|YP_937608.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|126434155|ref|YP_001069846.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|108768976|gb|ABG07698.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119693745|gb|ABL90818.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] gi|126233955|gb|ABN97355.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=205 Score = 80.9 bits (198), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/197 (32%), Positives = 95/197 (49%), Gaps = 3/197 (1%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 + +GR+T+ AI+ AAR + G TT+ADIT+ AG+S A FY Y+D KE ++ A Sbjct 9 SSKGRQTRLAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFDDKEDLLAALAQS 68 Query 66 FRDD-ANQRALSV-IRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F D LSV + DRE +W ++ + I+V+QLA FA Sbjct 69 FLHDVVAPSGLSVPLPSSPDDREFFTTVVTGYWNIFKQNIGIMIAVAQLAAAQQRFADLQ 128 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDD 183 E + + I +V+ AQ+ GY + + A AI +F F + + G Q D Sbjct 129 HEFRRFGMDVIAASVRHAQSQGYGAELNAEYTAAAIALLFENFTVVMV-GTSGLGVQMSD 187 Query 184 QACIQTLANIYYRAIYS 200 I TL+ I+ + +Y Sbjct 188 ADAIATLSTIWKKTLYG 204 >gi|183981507|ref|YP_001849798.1| transcriptional regulatory protein [Mycobacterium marinum M] gi|183174833|gb|ACC39943.1| transcriptional regulatory protein [Mycobacterium marinum M] Length=213 Score = 80.1 bits (196), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 57/202 (29%), Positives = 94/202 (47%), Gaps = 7/202 (3%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 + +GR+T+ AI+ AAR + G TT+ADIT+ AG+S+A FY Y+ KE ++ A Sbjct 11 SSKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQS 70 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F D +S+ D + + A +W ++ + I+V QLA FA Sbjct 71 FLHDVVTPSGVSLQLPDSPDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQ 130 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQP-- 181 ++ + + I +V+ AQ GY +P A AI +F F + + S Sbjct 131 NQFRRFGMDIIAASVRHAQDQGYGTELNPDHTAVAIALLFENFTSVLVGTSGSSGPGGLG 190 Query 182 ---DDQACIQTLANIYYRAIYS 200 D+ I TL+ I+ + +Y Sbjct 191 VTITDEDAITTLSRIWKKTLYG 212 >gi|118617937|ref|YP_906269.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] gi|118570047|gb|ABL04798.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99] Length=213 Score = 79.0 bits (193), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 56/202 (28%), Positives = 93/202 (47%), Gaps = 7/202 (3%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 + +GR+T+ AI+ AR + G TT+ADIT+ AG+S+A FY Y+ KE ++ A Sbjct 11 SSKGRQTRQAIEQVARKLFAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQS 70 Query 66 FRDD-ANQRALSVIRHGLSDRERAYEAAA-AHWYTYRNRLAEAISVSQLAMVSDDFAQYW 123 F D +S+ D + + A +W ++ + I+V QLA FA Sbjct 71 FLHDVVTPSGVSLQLPDSPDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQ 130 Query 124 SEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQP-- 181 ++ + + I +V+ AQ GY +P A AI +F F + + S Sbjct 131 NQFRRFGMDIIAASVRHAQDQGYGTELNPDHTAVAIALLFENFTSVLVGTSGSSGPGGLG 190 Query 182 ---DDQACIQTLANIYYRAIYS 200 D+ I TL+ I+ + +Y Sbjct 191 VTITDEDAITTLSRIWKKTLYG 212 >gi|291439099|ref|ZP_06578489.1| conserved hypothetical protein [Streptomyces ghanaensis ATCC 14672] gi|291341994|gb|EFE68950.1| conserved hypothetical protein [Streptomyces ghanaensis ATCC 14672] Length=212 Score = 76.6 bits (187), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 56/196 (29%), Positives = 93/196 (48%), Gaps = 11/196 (5%) Query 8 RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFR 67 R +T+AA+ AAR + G L T + DITA AGRS SFY ++ K+ +++ Sbjct 12 RAAQTRAALLDAARGLFNDRGYLNTKITDITAAAGRSTGSFYEHFAGKDELLQALLAEME 71 Query 68 DDANQRALSVIR---HGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDD--FAQY 122 D ++R + + H L+DR++ + W R +++ Q AMV+DD + Sbjct 72 DAIDERMVGLEHPRDHDLTDRDQLRDHVGVAWTVMRQNRPVTLALFQ-AMVADDPGTGRA 130 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPD 182 W ++ + I E ++ G+ + DP+ +A AI AM Y L+ G D Sbjct 131 WRDLRE-QTGTIREHLEYLVERGHQLPGDPEFIAAAIGAMLVTLNYAVLTPP----GGED 185 Query 183 DQACIQTLANIYYRAI 198 DQ I TL ++ + Sbjct 186 DQHVIDTLTDLLLHGL 201 >gi|300782957|ref|YP_003763248.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299792471|gb|ADJ42846.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340524333|gb|AEK39538.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=205 Score = 74.3 bits (181), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 51/197 (26%), Positives = 87/197 (45%), Gaps = 1/197 (0%) Query 7 QRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRF 66 ++ T+ A+ AAA+ V R G L T + DITAEAGR+A SFYN++ KE ++ Sbjct 8 EKAAETEVALKAAAKRVFARKGYLNTKITDITAEAGRAAGSFYNHFAGKEELLEALMADI 67 Query 67 RDDANQRALSVIR-HGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSE 125 ++ A S + SD +W YR+ A +++ Q AMVS+ FA+ + Sbjct 68 AASGDESADSEEHLNDFSDPAAVRWHVKQYWDFYRDNAATMLALRQAAMVSESFARTLAR 127 Query 126 ICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQA 185 + + + + G + DP + + + F L G P D+ Sbjct 128 FGASQAADLDDHLAHITRAGLRLPADPGHSGALMYHLVDSFAATWLHGSAPDGTPPTDEE 187 Query 186 CIQTLANIYYRAIYSKE 202 ++ L YR + ++ Sbjct 188 AVELLTRFIYRGLTGRD 204 >gi|302524320|ref|ZP_07276662.1| predicted protein [Streptomyces sp. AA4] gi|302433215|gb|EFL05031.1| predicted protein [Streptomyces sp. AA4] Length=206 Score = 70.9 bits (172), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 55/202 (28%), Positives = 93/202 (47%), Gaps = 12/202 (5%) Query 8 RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFR 67 + T+ A+ AA+ V G L T + DIT EAGR+A SFYN++ SKE ++ Sbjct 9 KAAETETALKEAAKRVFAAKGYLNTKITDITKEAGRAAGSFYNHFASKEELLVALLADLA 68 Query 68 DDANQRALSVIRHGLSDRERAYEAAAAHWYT------YRNRLAEAISVSQLAMVSDDFAQ 121 D++Q+A LSD + AA W+ YR +++ Q AMV++DFA Sbjct 69 ADSDQQAAG--EGHLSDFS---DPAAVRWHVRQYWDFYRANAPTMLALRQAAMVNEDFAA 123 Query 122 YWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYL-QLSGKRSRRGQ 180 ++ S + + ++ A G + + QL + + + F + L+ + Q Sbjct 124 TYANFGATQASDVEDHLEHVTAAGLRLPANTQLTIAMMYQLIDNFAQMWLLTPPPAGWNQ 183 Query 181 PDDQACIQTLANIYYRAIYSKE 202 P D+ I+ L YR ++ Sbjct 184 PSDEEAIEALTRFVYRGFTGRD 205 >gi|329936770|ref|ZP_08286477.1| A-factor receptor-like protein [Streptomyces griseoaurantiacus M045] gi|329304000|gb|EGG47883.1| A-factor receptor-like protein [Streptomyces griseoaurantiacus M045] Length=211 Score = 69.7 bits (169), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 57/191 (30%), Positives = 91/191 (48%), Gaps = 11/191 (5%) Query 8 RGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFR 67 R +T+AA+ AAR + G L T + DITA AGRS SFY ++ KE +++ Sbjct 11 RAAQTRAALLDAARGLFSERGYLNTKITDITAAAGRSTGSFYEHFAGKEELLQALLAEME 70 Query 68 D--DANQRALSVIR-HGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDD--FAQY 122 D R L R H L+DRE+ + A W R A+++ Q AMV+DD + Sbjct 71 GAIDTRMRGLEHPRDHDLTDREQLRDHLDAAWTVMRQNRPVALALFQ-AMVADDPGTGRA 129 Query 123 WSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPD 182 W ++ + + I E ++ G+ + DP+ +A ++ AM Y L+ G D Sbjct 130 WRDLRE-QTATIREHLEYLVERGHRLPGDPEFVAASMGAMLVTLNYALLTPP----GGED 184 Query 183 DQACIQTLANI 193 + TL ++ Sbjct 185 APDVVDTLTDL 195 >gi|148556307|ref|YP_001263889.1| TetR family transcriptional regulator [Sphingomonas wittichii RW1] gi|148501497|gb|ABQ69751.1| transcriptional regulator, TetR family [Sphingomonas wittichii RW1] Length=207 Score = 63.9 bits (154), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 38/164 (24%), Positives = 72/164 (44%), Gaps = 0/164 (0%) Query 5 PTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWAL 64 P ++ T+ + AAR V R+ +ADI AEAG++ FY Y++ K+ + Sbjct 11 PRRKAEVTREKLIDAARVVFSRDHYQNARIADICAEAGKAVGVFYRYFNDKQDIFIACVD 70 Query 65 RFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWS 124 +F +D N+ + + ++ +W YR + + MV+ + A W Sbjct 71 QFFEDLNRASPPAAEFETNTLGAIRQSTTIYWIKYRQYYGVVAGLFETGMVNPEIAGLWH 130 Query 125 EICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCY 168 ++ + +++ A G C+ DP + A A++ M CY Sbjct 131 KVRDNGMKRFAFRIRKQHAAGKCLDLDPDIAASALMGMLEFSCY 174 >gi|29827923|ref|NP_822557.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29605024|dbj|BAC69092.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=242 Score = 62.8 bits (151), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 57/197 (29%), Positives = 93/197 (48%), Gaps = 5/197 (2%) Query 6 TQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALR 65 T+RG RT+AA+ AAR V R+G L T + DIT EA +A SFY Y+ +KE ++ L Sbjct 41 TKRGARTRAALVKAARKVFERDGYLDTRLTDITKEAQCAAGSFYTYFTNKEEVLAAVLLE 100 Query 66 FRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAIS-VSQLAMVSDDFAQYWS 124 ++D +S + G D EA+ + R A+ ++ + Q+A V +F + S Sbjct 101 AQEDMMHPGMSRV-QGSDDPYAVLEASNRAYLEAYKRNAKLMALLEQVAQVEPEFRTFRS 159 Query 125 EICQIPISFITETVKRAQAHGYC-VGDDPQLMAEAIVAMFNQFCYLQ-LSGKRSRRGQPD 182 I + QA G G DP + + A+ M + Y + G+R P Sbjct 160 RRADAFIRRNARGIADLQARGVADRGVDPLMASRALSGMVSVMAYNAFVLGERHEEDAPV 219 Query 183 D-QACIQTLANIYYRAI 198 D + + T+ ++ A+ Sbjct 220 DFEELVSTVTRLWANAL 236 Lambda K H 0.321 0.130 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 233186096862 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40