BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0302 Length=210 Score E Sequences producing significant alignments: (Bits) Value gi|15607443|ref|NP_214816.1| TetR/ACRR family transcriptional re... 427 7e-118 gi|31791481|ref|NP_853974.1| TetR/ACRR family transcriptional re... 425 2e-117 gi|289756367|ref|ZP_06515745.1| transcriptional regulator [Mycob... 423 6e-117 gi|308370369|ref|ZP_07421253.2| transcriptional regulator, tetR/... 393 8e-108 gi|289748786|ref|ZP_06508164.1| transcriptional regulator, tetR/... 380 1e-103 gi|298523771|ref|ZP_07011180.1| conserved hypothetical protein [... 319 1e-85 gi|298523774|ref|ZP_07011183.1| conserved hypothetical protein [... 268 3e-70 gi|302556056|ref|ZP_07308398.1| TetR family transcriptional regu... 102 4e-20 gi|29826977|ref|NP_821611.1| TetR family transcriptional regulat... 100 1e-19 gi|326384832|ref|ZP_08206508.1| TetR family transcriptional regu... 98.6 5e-19 gi|41407830|ref|NP_960666.1| hypothetical protein MAP1732c [Myco... 98.2 8e-19 gi|317126255|ref|YP_004100367.1| TetR transcriptional regulator ... 94.4 9e-18 gi|120401610|ref|YP_951439.1| TetR family transcriptional regula... 92.8 3e-17 gi|183981519|ref|YP_001849810.1| transcriptional regulatory prot... 92.0 5e-17 gi|240168605|ref|ZP_04747264.1| transcriptional regulatory prote... 91.3 8e-17 gi|317509262|ref|ZP_07966883.1| tetR family bacterial regulatory... 91.3 8e-17 gi|333989769|ref|YP_004522383.1| transcriptional regulator [Myco... 91.3 9e-17 gi|302527291|ref|ZP_07279633.1| TetR-type regulator [Streptomyce... 89.4 3e-16 gi|295681487|ref|YP_003610061.1| TetR family transcriptional reg... 87.8 9e-16 gi|209521163|ref|ZP_03269889.1| transcriptional regulator, TetR ... 87.4 1e-15 gi|221197562|ref|ZP_03570609.1| transcriptional regulator, TetR ... 86.7 2e-15 gi|329935072|ref|ZP_08285086.1| TetR family transcriptional regu... 86.3 3e-15 gi|17425272|dbj|BAB78770.1| lexA repressor-like protein [Terraba... 84.0 1e-14 gi|340793237|ref|YP_004758700.1| TetR DNA-binding transcription ... 82.0 6e-14 gi|166197613|dbj|BAG06219.1| TetR-type regulator [Nocardioides s... 80.5 2e-13 gi|325529135|gb|EGD06117.1| transcriptional regulator, TetR fami... 79.0 4e-13 gi|291442666|ref|ZP_06582056.1| transcriptional regulator [Strep... 78.2 7e-13 gi|119714486|ref|YP_921451.1| regulatory protein TetR [Nocardioi... 76.6 2e-12 gi|326333238|ref|ZP_08199485.1| LigA [Nocardioidaceae bacterium ... 74.7 8e-12 gi|298523775|ref|ZP_07011184.1| conserved hypothetical protein [... 72.8 3e-11 gi|299534318|ref|ZP_07047662.1| TetR family transcriptional regu... 71.2 8e-11 gi|56963375|ref|YP_175106.1| hypothetical protein ABC1610 [Bacil... 69.7 3e-10 gi|295707078|ref|YP_003600153.1| TetR family transcriptional reg... 68.9 4e-10 gi|317124915|ref|YP_004099027.1| TetR transcriptional regulator ... 68.9 4e-10 gi|345442122|gb|AEN87139.1| putative transcriptional regulator Y... 68.6 6e-10 gi|294501731|ref|YP_003565431.1| TetR family transcriptional reg... 67.8 1e-09 gi|332670780|ref|YP_004453788.1| regulatory protein TetR [Cellul... 67.0 2e-09 gi|329938413|ref|ZP_08287838.1| A-factor receptor-like protein [... 67.0 2e-09 gi|329121820|ref|ZP_08250436.1| hypothetical protein HMPREF9083_... 65.5 5e-09 gi|313892658|ref|ZP_07826244.1| transcriptional regulator, TetR ... 65.5 5e-09 gi|337746243|ref|YP_004640405.1| TetR family transcriptional reg... 64.7 8e-09 gi|251799080|ref|YP_003013811.1| TetR family transcriptional reg... 64.7 8e-09 gi|334337205|ref|YP_004542357.1| regulatory protein TetR [Isopte... 64.7 9e-09 gi|315443504|ref|YP_004076383.1| TetR family transcriptional reg... 64.7 9e-09 gi|62860884|gb|AAY16477.1| transcriptional regulator [Bifidobact... 63.9 1e-08 gi|336428636|ref|ZP_08608615.1| hypothetical protein HMPREF0994_... 63.2 2e-08 gi|145223048|ref|YP_001133726.1| TetR family transcriptional reg... 63.2 2e-08 gi|336320465|ref|YP_004600433.1| regulatory protein TetR [Cellvi... 63.2 2e-08 gi|226314645|ref|YP_002774541.1| transcriptional regulator [Brev... 63.2 3e-08 gi|336176474|ref|YP_004581849.1| regulatory protein TetR [Franki... 62.8 3e-08 >gi|15607443|ref|NP_214816.1| TetR/ACRR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15839687|ref|NP_334724.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|121636217|ref|YP_976440.1| TetR/AcrR family transcriptional regulator [Mycobacterium bovis BCG str. Pasteur 1173P2] 58 more sequence titles Length=210 Score = 427 bits (1097), Expect = 7e-118, Method: Compositional matrix adjust. Identities = 209/210 (99%), Positives = 210/210 (100%), Gaps = 0/210 (0%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG Sbjct 1 MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS Sbjct 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 Query 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH Sbjct 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 Query 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 LEPDTTDVERMYRRLRQALEALIPVLLEET Sbjct 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 >gi|31791481|ref|NP_853974.1| TetR/ACRR family transcriptional regulator [Mycobacterium bovis AF2122/97] gi|31617067|emb|CAD93174.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR/ACRR-FAMILY) [Mycobacterium bovis AF2122/97] Length=210 Score = 425 bits (1093), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 208/210 (99%), Positives = 209/210 (99%), Gaps = 0/210 (0%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG Sbjct 1 MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS Sbjct 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 Query 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 QDP VAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH Sbjct 121 QDPVVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 Query 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 LEPDTTDVERMYRRLRQALEALIPVLLEET Sbjct 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 >gi|289756367|ref|ZP_06515745.1| transcriptional regulator [Mycobacterium tuberculosis T85] gi|294995060|ref|ZP_06800751.1| transcriptional regulator, tetR/acrR-family protein [Mycobacterium tuberculosis 210] gi|289711931|gb|EFD75943.1| transcriptional regulator [Mycobacterium tuberculosis T85] gi|326906057|gb|EGE52990.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis W-148] gi|339293358|gb|AEJ45469.1| TetR/AcrR family transcriptional regulator [Mycobacterium tuberculosis CCDC5079] gi|339297005|gb|AEJ49115.1| TetR/AcrR family transcriptional regulator [Mycobacterium tuberculosis CCDC5180] Length=210 Score = 423 bits (1088), Expect = 6e-117, Method: Compositional matrix adjust. Identities = 208/210 (99%), Positives = 209/210 (99%), Gaps = 0/210 (0%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG Sbjct 1 MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 VLAAMMERGAQRFFAAIPTWDEA GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS Sbjct 61 VLAAMMERGAQRFFAAIPTWDEADGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 Query 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH Sbjct 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 Query 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 LEPDTTDVERMYRRLRQALEALIPVLLEET Sbjct 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 >gi|308370369|ref|ZP_07421253.2| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu003] gi|308371639|ref|ZP_07425621.2| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu004] gi|308372858|ref|ZP_07430155.2| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu005] gi|308376357|ref|ZP_07438567.2| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu008] gi|308332209|gb|EFP21060.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu003] gi|308336011|gb|EFP24862.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu004] gi|308339597|gb|EFP28448.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu005] gi|308351331|gb|EFP40182.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis SUMu008] Length=231 Score = 393 bits (1010), Expect = 8e-108, Method: Compositional matrix adjust. Identities = 204/209 (98%), Positives = 206/209 (99%), Gaps = 0/209 (0%) Query 2 GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGV 61 G ++KQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGV Sbjct 23 GRSRQEKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGV 82 Query 62 LAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ 121 LAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ Sbjct 83 LAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ 142 Query 122 DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHL 181 DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHL Sbjct 143 DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHL 202 Query 182 EPDTTDVERMYRRLRQALEALIPVLLEET 210 EPDTTDVERMYRRLRQALEALIPVLLEET Sbjct 203 EPDTTDVERMYRRLRQALEALIPVLLEET 231 >gi|289748786|ref|ZP_06508164.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis T92] gi|289689373|gb|EFD56802.1| transcriptional regulator, tetR/acrR-family [Mycobacterium tuberculosis T92] Length=205 Score = 380 bits (975), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 185/186 (99%), Positives = 186/186 (100%), Gaps = 0/186 (0%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG Sbjct 1 MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS Sbjct 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 Query 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH Sbjct 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 Query 181 LEPDTT 186 LEPDTT Sbjct 181 LEPDTT 186 >gi|298523771|ref|ZP_07011180.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298493565|gb|EFI28859.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=162 Score = 319 bits (818), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 154/156 (99%), Positives = 155/156 (99%), Gaps = 0/156 (0%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG Sbjct 1 MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS Sbjct 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 Query 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGK 156 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPP K Sbjct 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPAK 156 >gi|298523774|ref|ZP_07011183.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298493568|gb|EFI28862.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=141 Score = 268 bits (686), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 130/131 (99%), Positives = 131/131 (100%), Gaps = 0/131 (0%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +GVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG Sbjct 1 MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS Sbjct 61 VLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS 120 Query 121 QDPAVAAVVRR 131 QDPAVAAVVRR Sbjct 121 QDPAVAAVVRR 131 >gi|302556056|ref|ZP_07308398.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302473674|gb|EFL36767.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=209 Score = 102 bits (253), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 69/178 (39%), Positives = 94/178 (53%), Gaps = 7/178 (3%) Query 11 QGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGA 70 +G RSR++ILD LMA G+AATSIS I ACGL SSIYWHF SK+G+ A++ER Sbjct 3 RGARSRDAILDTAGDLMARHGFAATSISMISTACGLPVSSIYWHFRSKDGIYVAVLERAR 62 Query 71 QRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAV-- 128 AA+P + V QR + L EL +HP ++L L M + QD + AAV Sbjct 63 TALLAALPPAEVPGADVAQRLDTFLAELEGAFQRHPRGVKLLLGLGMVQ-QDASTAAVAE 121 Query 129 VRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTT 186 VR R+ + R+S++ + P AD E+ F + + G A EP T Sbjct 122 VRHYRDALVDWARESVSSVFALGERPQVAD----EMARFTLRMVSGTAVARWFEPQTV 175 >gi|29826977|ref|NP_821611.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29604074|dbj|BAC68146.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=219 Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 72/179 (41%), Positives = 98/179 (55%), Gaps = 7/179 (3%) Query 9 QQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMER 68 Q +G RSR++ILD LMA GYAATSIS I ACGL SS+YWHFGSK+G+ A++ER Sbjct 7 QNRGARSRDAILDTAGELMARYGYAATSISMISAACGLPTSSLYWHFGSKDGIYIAVLER 66 Query 69 GAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAV 128 AA+P + V QR + L E+ +HP LRL L M + QD + AAV Sbjct 67 ARTELLAALPPAEVPGADVIQRLDTFLAEVRDAFERHPHGLRLLLGLGMVQ-QDASAAAV 125 Query 129 --VRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDT 185 VR+ R+ + R+S++ + P AD EL F + ++ G A +P T Sbjct 126 AEVRQYRDALVVWARESVSAVFGLRDRPEVAD----ELARFTLRMASGTAVALWFDPGT 180 >gi|326384832|ref|ZP_08206508.1| TetR family transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] gi|326196494|gb|EGD53692.1| TetR family transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] Length=217 Score = 98.6 bits (244), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 57/188 (31%), Positives = 101/188 (54%), Gaps = 8/188 (4%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 ++++ G S+ ILDA + + +GY TSI + CGL SSIYWHF K+ ++AA+ Sbjct 15 RRRRANGAASKAKILDAATEIASERGYEGTSIGLVSKRCGLPASSIYWHFADKDDLIAAV 74 Query 66 MERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS-QDPA 124 +ER R+ +A D+ G +QR ++ PDFLRL +L++ER ++P Sbjct 75 IERSFDRWLSAWSLSDD--GTTQQRVADMSMQVAEALLDSPDFLRLGLMLALERRPEEPR 132 Query 125 VAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPD 184 + +VR+ A+ + R++ L PG + V +L +A+A +DG++ A + + Sbjct 133 ARTMYLQVRDQAMDQLREAARTL-----APGLDESAVDQLATYAIAGADGLFIAKEIGGE 187 Query 185 TTDVERMY 192 D+ ++ Sbjct 188 AVDLPALF 195 >gi|41407830|ref|NP_960666.1| hypothetical protein MAP1732c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396184|gb|AAS04049.1| hypothetical protein MAP_1732c [Mycobacterium avium subsp. paratuberculosis K-10] Length=215 Score = 98.2 bits (243), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 62/190 (33%), Positives = 98/190 (52%), Gaps = 8/190 (4%) Query 4 PAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLA 63 P ++K+ GE SRE ILDA + A +GY ATSI + CGL SSIYWHF +K+ ++A Sbjct 12 PKRRKRADGEMSRERILDAATEIAAERGYEATSIGLVSAKCGLPASSIYWHFKNKDDLIA 71 Query 64 AMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ-D 122 A++ER + A DE G R ++ + PDF+RL +L++ER + Sbjct 72 AVIERSFADWRKAWQVPDE--GAPRDRLAGLAMQIAKVLMDSPDFIRLGLMLALERRPVE 129 Query 123 PAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLE 182 P A+ + R A D + L PG D + +L +A+A +DG++ A + Sbjct 130 PRARAMFIQARAQAYDELADIVREL-----APGLTDKQIDQLVTYAIAGADGLFIAREIG 184 Query 183 PDTTDVERMY 192 D ++ ++ Sbjct 185 GDAVNLVGLF 194 >gi|317126255|ref|YP_004100367.1| TetR transcriptional regulator [Intrasporangium calvum DSM 43043] gi|315590343|gb|ADU49640.1| regulatory protein TetR [Intrasporangium calvum DSM 43043] Length=211 Score = 94.4 bits (233), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 59/180 (33%), Positives = 95/180 (53%), Gaps = 4/180 (2%) Query 1 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEG 60 +G ++ +QG++SR +ILDAT + A +GY T+++ +++A GL SSIYWHFGSK+ Sbjct 1 MGRKTDRRHRQGDQSRLAILDATLAIAAERGYDGTTVALVQEATGLPASSIYWHFGSKDA 60 Query 61 VLAAMMERGAQRFFAAIPTWDEAHGP--VEQRSERQLTELVSLQSQHPDFLRLFYLLSM- 117 +LAA +E + + PTW + P + R ER+ + P F L LL++ Sbjct 61 LLAATLEHSYRSWRDTAPTWVASVEPEDLSDRVERRFQRAAQALTTSPQFWSLGLLLTLQ 120 Query 118 ERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYF 177 +R ++PA + VR A RD +L D + +L L F + L DG++ Sbjct 121 QRVKEPAARRLYADVRTDTEAAIRDWWATVLSPDACRAEPELTT-RLARFHMMLMDGLFL 179 >gi|120401610|ref|YP_951439.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954428|gb|ABM11433.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=208 Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 67/210 (32%), Positives = 107/210 (51%), Gaps = 16/210 (7%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 ++++ GE SR ILDA + A +GY TSI + CGL SSIYWHF K+ ++AA+ Sbjct 8 RRRRADGELSRRRILDAATEIAAERGYEGTSIGAVSAKCGLPASSIYWHFKDKDDLIAAV 67 Query 66 MERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQ----HPDFLRLFYLLSMERSQ 121 +ER F + W P + + +L E+ ++ PDFLRL +L++ER Sbjct 68 IERS---FANWLTVW---QLPDDVMARDRLMEVAMGTAKAVLDSPDFLRLGLMLALERRP 121 Query 122 -DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH 180 +P A+ +VR A A SI D+ ++ V L+ +A+A +DG++ A Sbjct 122 VEPKARAMFIQVREQAFAALATSI-----RDLGLDLSEEQVRHLSTYAIAGADGLFIAKE 176 Query 181 LEPDTTDVERMYRRLRQALEALIPVLLEET 210 + DT D+ ++ QAL ++EE Sbjct 177 IGGDTVDLMALFALHGQALYDTALRMIEEN 206 >gi|183981519|ref|YP_001849810.1| transcriptional regulatory protein [Mycobacterium marinum M] gi|183174845|gb|ACC39955.1| transcriptional regulatory protein [Mycobacterium marinum M] Length=222 Score = 92.0 bits (227), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 57/195 (30%), Positives = 96/195 (50%), Gaps = 16/195 (8%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 ++ + GE SR ILDA + A +GY TSI+ + CGL SSIYWHF K+ ++AA+ Sbjct 15 RRGRADGELSRARILDAATEIAAERGYEGTSIALVSAKCGLPASSIYWHFKDKDDLIAAV 74 Query 66 MERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQ-------HPDFLRLFYLLSME 118 +ER F + W G + + + V L +Q PDF+RL +L++E Sbjct 75 IERS---FGGWLTAWQIPEGQSGDETIQGAEQFVGLATQTAKALLDSPDFIRLGLMLALE 131 Query 119 RS-QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYF 177 R +P + VR A + + + PG + + +L +A+A +DG++ Sbjct 132 RRPAEPRARTMFLEVRAQAFGQLIGNFGRFM-----PGLTEAQIYQLATYAMAGADGLFI 186 Query 178 AGHLEPDTTDVERMY 192 A ++ D ++ M+ Sbjct 187 AKEIDGDAVNLIEMF 201 >gi|240168605|ref|ZP_04747264.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=214 Score = 91.3 bits (225), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 61/206 (30%), Positives = 103/206 (50%), Gaps = 10/206 (4%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 ++ + GE SR ILDA + A +GY TSI+ + CGL SSIYWHF K+ ++AA+ Sbjct 13 RRGRADGELSRARILDAATEIAAERGYEGTSIALVSAKCGLPASSIYWHFKDKDDLIAAV 72 Query 66 MERGAQRFFAAIPTWDEAH-GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERS-QDP 123 +ER F A W G E+R + T++ PDF+RL +L++ER +P Sbjct 73 IERS---FGAWESAWGAPESGTAEERFQGLATQIAKALLDAPDFIRLGLMLALERRPTEP 129 Query 124 AVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEP 183 + +VR A + ++ + PG D ++ +A+A +DG++ A + Sbjct 130 RARTMFLQVRAQAFGQLVENF-----REFTPGLTDAHAHQVATYAMAGADGLFIAKEVGG 184 Query 184 DTTDVERMYRRLRQALEALIPVLLEE 209 D D+ ++ +A+ + +EE Sbjct 185 DAVDLVALFELHARAIYDMARRFVEE 210 >gi|317509262|ref|ZP_07966883.1| tetR family bacterial regulatory protein [Segniliparus rugosus ATCC BAA-974] gi|316252472|gb|EFV11921.1| tetR family bacterial regulatory protein [Segniliparus rugosus ATCC BAA-974] Length=213 Score = 91.3 bits (225), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 61/188 (33%), Positives = 93/188 (50%), Gaps = 6/188 (3%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 ++++ GERSR IL+A + +GY TSIS + +ACGL SSIYWHF K+ ++AA Sbjct 9 RRRRANGERSRAKILEAAMLVAGERGYEGTSISAVSEACGLPASSIYWHFKDKDELIAAA 68 Query 66 MERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAV 125 ++ G + + E G E+R+ + P FLRL +LS+ER A Sbjct 69 LQHGYDQLSSYFVLPGEEAGCPEERAAQMARSFGEAIEARPTFLRLGLMLSLERRPTEAR 128 Query 126 A-AVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPD 184 A + VR A + L P D P VV +A+A DG++ A ++ D Sbjct 129 AREMFLHVRFLARQSVEGMLRELFP-DFPEPDFSTVV----TYAMAGGDGLFVAKEVDGD 183 Query 185 TTDVERMY 192 D+ R++ Sbjct 184 AVDLPRLF 191 >gi|333989769|ref|YP_004522383.1| transcriptional regulator [Mycobacterium sp. JDM601] gi|333485737|gb|AEF35129.1| transcriptional regulatory protein [Mycobacterium sp. JDM601] Length=211 Score = 91.3 bits (225), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 65/199 (33%), Positives = 101/199 (51%), Gaps = 22/199 (11%) Query 4 PAKKKQQQ----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKE 59 PA+ K+++ GE SR SILDA + A +GY TSI+ + CGL SSIYWHF +K+ Sbjct 4 PAQPKRRRTRADGELSRNSILDAATEIAAERGYEGTSIALVSAKCGLPASSIYWHFKNKD 63 Query 60 GVLAAMMERGAQRFFAAIPTWDEAH-GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSME 118 ++AA++ R F + + W G EQR T PDF+RL +L++E Sbjct 64 DLIAAVIARS---FSSWLSAWQVPEGGTAEQRFASVATRAAKALQDSPDFIRLGLMLALE 120 Query 119 RSQ-DPAVAAVVRRVRNTA----IARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSD 173 R +P A+ R A + FRD + L ++ V +L +A+A +D Sbjct 121 RRPVEPRARAMFLDTRIQARRQLVNDFRDFLPELTEAN---------VQQLADYALAGAD 171 Query 174 GVYFAGHLEPDTTDVERMY 192 G++ A + DT D+ ++ Sbjct 172 GLFIAKEIGGDTVDLLALF 190 >gi|302527291|ref|ZP_07279633.1| TetR-type regulator [Streptomyces sp. AA4] gi|302436186|gb|EFL08002.1| TetR-type regulator [Streptomyces sp. AA4] Length=223 Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 69/187 (37%), Positives = 91/187 (49%), Gaps = 20/187 (10%) Query 17 ESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFF-- 74 E ILD R+MA +GY+AT++S + GL S+IY HF SK G+L+A+MERGA FF Sbjct 27 EEILDTASRIMAERGYSATTMSVLSTETGLPKSAIYHHFQSKGGLLSAVMERGAYEFFRH 86 Query 75 ----AAIPTWD----EAHGPVEQRSERQLTELVSLQSQHPDFLR--LFYLLSMERSQDPA 124 A P D E G QR+ + PDFLR L L+S E D Sbjct 87 LRESQANPPQDLPPAELLGWFLQRTGEVF-------AAKPDFLRLHLILLMSAEAVADVE 139 Query 125 VAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPD 184 V ++ RVR R I+ S + P AD V L F +A DG + A EPD Sbjct 140 VKEIIERVRADGRQHMRRMISQSWAS-VGPEAADKVGEALDYFGIAGFDGAFVAWQAEPD 198 Query 185 TTDVERM 191 + ++M Sbjct 199 RSMRDQM 205 >gi|295681487|ref|YP_003610061.1| TetR family transcriptional regulator [Burkholderia sp. CCGE1002] gi|295441382|gb|ADG20550.1| transcriptional regulator, TetR family [Burkholderia sp. CCGE1002] Length=269 Score = 87.8 bits (216), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 69/201 (35%), Positives = 100/201 (50%), Gaps = 12/201 (5%) Query 9 QQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMER 68 ++G+RSR+ ILDA R+M+ GY TS+S + +A G+ S+IY HFGSK G+LA +M + Sbjct 27 NRRGQRSRQEILDAAARVMSAYGYTGTSMSALVEATGIPKSAIYHHFGSKAGLLAEVMAQ 86 Query 69 GAQRFFAAIPTWDEAH-GPVEQRSERQ-----LTELVSLQSQHPDFLRLFYLLSM-ERSQ 121 GA+ FFAA+ EAH P E + R+ L + + +FLRL ++ M + Sbjct 87 GARGFFAAM---REAHQNPPEGGTSRERLGWYLKKTGEVFQHRENFLRLLVVMVMSNEAA 143 Query 122 DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHL 181 +P V VRN R+ I ++ A V EL F + DG F Sbjct 144 EPEAIQTVFEVRNEGRDYMREMIRSTFSAE-GDAVASAVADELAYFGMLGFDGA-FVSFQ 201 Query 182 EPDTTDVERMYRRLRQALEAL 202 D +E +L AL AL Sbjct 202 SGDNRSMETHMAQLTDALIAL 222 >gi|209521163|ref|ZP_03269889.1| transcriptional regulator, TetR family [Burkholderia sp. H160] gi|209498406|gb|EDZ98535.1| transcriptional regulator, TetR family [Burkholderia sp. H160] Length=239 Score = 87.4 bits (215), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/207 (33%), Positives = 106/207 (52%), Gaps = 21/207 (10%) Query 9 QQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMER 68 ++G+RSR+ ILDA R+M+ GYA TS+S + +A G+ S+IY HFGSK G+LA +M + Sbjct 9 NRRGQRSRQEILDAASRVMSAYGYAGTSMSALVEATGIPKSAIYHHFGSKAGLLAEVMAQ 68 Query 69 GAQRFFAAIPTWDEAH-GPVEQRSERQ-----LTELVSLQSQHPDFLRLFYLLSM-ERSQ 121 GA+ FFAA+ EAH P E + R+ L + + +FLRL ++ M + Sbjct 69 GARGFFAAM---REAHQNPPEGGTSRERLGWYLQKTGEVFEHRENFLRLLVVMVMSNEAA 125 Query 122 DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVA---ELTAFAVALSDGVYFA 178 +P +V VR+ RD + ++ S ++ A EL F + DG + Sbjct 126 EPEAMQIVVEVRDEG----RDYMREMIRSAFSAEGDEVASAIGEELAYFGMLGFDGAF-- 179 Query 179 GHLEPDTTDVERMYRRLRQALEALIPV 205 + + D M + Q +ALI + Sbjct 180 --VSIQSGDNRSMEMHMAQLTDALIAL 204 >gi|221197562|ref|ZP_03570609.1| transcriptional regulator, TetR family protein [Burkholderia multivorans CGD2M] gi|221204235|ref|ZP_03577253.1| transcriptional regulator, TetR family protein [Burkholderia multivorans CGD2] gi|221176401|gb|EEE08830.1| transcriptional regulator, TetR family protein [Burkholderia multivorans CGD2] gi|221184116|gb|EEE16516.1| transcriptional regulator, TetR family protein [Burkholderia multivorans CGD2M] Length=244 Score = 86.7 bits (213), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 53/134 (40%), Positives = 77/134 (58%), Gaps = 11/134 (8%) Query 9 QQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMER 68 ++G++SR+ ILDA R+M+ GYA TS+S + +A G+ S+IY HFGSK G+LA +M R Sbjct 9 NRRGQQSRQEILDAASRVMSAYGYAGTSMSALVEATGIPKSAIYHHFGSKAGLLAEVMAR 68 Query 69 GAQRFFAAIPTWDEAH------GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSM--ERS 120 GAQ FF A+ +AH G +R L ++ H +FLRL ++ M E + Sbjct 69 GAQGFFEAMR---DAHRDPPQGGTPRERLGWYLQRTGAVSVHHENFLRLLMVMVMTSEAT 125 Query 121 QDPAVAAVVRRVRN 134 P +V VRN Sbjct 126 DAPEAMEIVATVRN 139 >gi|329935072|ref|ZP_08285086.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329305317|gb|EGG49174.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=219 Score = 86.3 bits (212), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 68/211 (33%), Positives = 101/211 (48%), Gaps = 14/211 (6%) Query 5 AKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAA 64 A G SR+ ILDA L+ ++GY S+SD+ GL SSIY+HFG+K GVLAA Sbjct 6 ASAASDAGPNSRDLILDAARSLVTSQGYDGMSVSDLCARSGLPASSIYYHFGNKLGVLAA 65 Query 65 MMERGAQRFFAAIPT-WDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDP 123 +++R Q A P G R E +T + + PD+LRL +S+ R +D Sbjct 66 LLDRTFQELHAQFPNPASFREGDPLDRFEAWVTTACASLDRRPDYLRLLLAVSVGRHKDT 125 Query 124 -AVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLV-------VAELTAFAVALS-DG 174 V + VRR+R+ A + +++T + D +LV A AV S DG Sbjct 126 EMVRSTVRRIRDYAHTSWVEALTPVFAPDGGTENEELVDRLAVLGRAMTDGLAVTNSFDG 185 Query 175 VYFAGHLEPDTTDVERMYRRLRQALEALIPV 205 + ++ H+ P M R L + +PV Sbjct 186 LSYSAHVAP----FVAMVRALAAETDRAVPV 212 >gi|17425272|dbj|BAB78770.1| lexA repressor-like protein [Terrabacter sp.] Length=252 Score = 84.0 bits (206), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 39/73 (54%), Positives = 52/73 (72%), Gaps = 0/73 (0%) Query 5 AKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAA 64 A + QQ+GE+SRE ILDA RLM +GY TSI+ + +A G+ S ++ HFGSK G+L A Sbjct 42 ANRTQQRGEKSREEILDAASRLMGERGYDGTSIAAVSEAVGIPKSLVFHHFGSKIGLLTA 101 Query 65 MMERGAQRFFAAI 77 +M RGA RFF A+ Sbjct 102 VMTRGAYRFFEAM 114 >gi|340793237|ref|YP_004758700.1| TetR DNA-binding transcription regulator [Corynebacterium variabile DSM 44702] gi|340533147|gb|AEK35627.1| TetR DNA-binding transcription regulator [Corynebacterium variabile DSM 44702] Length=229 Score = 82.0 bits (201), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 55/162 (34%), Positives = 83/162 (52%), Gaps = 6/162 (3%) Query 12 GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQ 71 GERSR+ ILDA + +GY TSI++I CGL SSIYWHF K+ ++A ++E Sbjct 30 GERSRQKILDAAAEIATERGYDGTSIAEISRRCGLPASSIYWHFKDKDDLMATVIE---D 86 Query 72 RFFAAIPTWD-EAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSME-RSQDPAVAAVV 129 F +WD +A G + +L+ +HP FL + L+++ RS DP + Sbjct 87 SFDDWNQSWDIDADGNILLELFAIAEQLIGALQEHPQFLHIGLPLALQKRSDDPRPRRMY 146 Query 130 RRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVAL 171 ++R ARF + I S +P G+ ++ L A A L Sbjct 147 LQMRENLTARF-EKIGETHFSHVPVGRRTAIITYLIAGAEGL 187 >gi|166197613|dbj|BAG06219.1| TetR-type regulator [Nocardioides sp. DF412] Length=217 Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 66/181 (37%), Positives = 94/181 (52%), Gaps = 5/181 (2%) Query 15 SRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFF 74 S+E +LDA R+MA +GYA TSIS I G+ S+IY HF SK GVL+A++ERGA+ +F Sbjct 19 SKEEVLDAAARVMAQRGYAGTSISAITAESGVPVSAIYHHFRSKGGVLSAVLERGARDYF 78 Query 75 AAIPTWDE---AHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSM-ERSQDPAVAAVVR 130 AA+ A G +R + + + +P FLRL L + + + D VA + R Sbjct 79 AAMRAAHAEPPAGGTHRERLAWFMERTAEVFAANPGFLRLHLQLLLSDEAADAEVAEMNR 138 Query 131 RVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVER 190 +VR A R I+ +D AD V L FA+A DG + E + T + Sbjct 139 QVREEGRAYMRHMISTAF-ADQGTAVADAVAQRLDYFAIAAFDGSFVNFQAEAERTVASQ 197 Query 191 M 191 M Sbjct 198 M 198 >gi|325529135|gb|EGD06117.1| transcriptional regulator, TetR family protein [Burkholderia sp. TJI49] Length=229 Score = 79.0 bits (193), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 58/176 (33%), Positives = 86/176 (49%), Gaps = 12/176 (6%) Query 9 QQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMER 68 ++G++SR+ ILDA R+M+ GYA TS+S + +A G+ S+IY HFGSK G+LA +M + Sbjct 9 NRRGQQSRQEILDAASRVMSAYGYAGTSMSALVEATGIPKSAIYHHFGSKAGLLAEVMAQ 68 Query 69 GAQRFFAAIPTWDEAH------GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSM--ERS 120 GA FF A+ +AH G +R L + +FLRL ++ M E + Sbjct 69 GAHGFFEAM---RDAHRDPPQDGTPRERLGWYLQRTGEVFVHRENFLRLLMVMVMTSEAT 125 Query 121 QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVY 176 P +V VRN R I ++ A V F +A DG + Sbjct 126 DAPEAMEIVATVRNEGRDYMRQMIRAAFSTE-GEAIAAAVAERFAHFGMAGFDGAF 180 >gi|291442666|ref|ZP_06582056.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672] gi|291345561|gb|EFE72517.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672] Length=216 Score = 78.2 bits (191), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 61/173 (36%), Positives = 89/173 (52%), Gaps = 18/173 (10%) Query 17 ESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAA 76 + ILDA R+M+ +GYA TS+S + GL S+ Y+HF SK G+LAA+ME+GA FFAA Sbjct 20 QEILDAAARVMSVRGYAGTSMSVLVKETGLPRSAFYYHFESKAGLLAAVMEQGAHAFFAA 79 Query 77 IPTWDEAH-GPVEQRSERQLTELV-----SLQSQHPDFLRLFYLLSMER--SQDPAVAAV 128 + EAH P + S R L + +F+RL +L M R ++ P Sbjct 80 M---REAHRNPPTEGSPRDLLRWYMRRTGDVMEDGEEFIRLLLVLVMSREAAEAPEALQT 136 Query 129 VRRVRNTAIARFRDSITHLLPSD-IPPGK--ADLVVAELTAFAVALSDGVYFA 178 V VR+ R + H++ S + G+ AD + L F +A DG + A Sbjct 137 VIAVRDEG----RAYMAHMIRSSFVSAGEETADRIAEALAPFGMAGYDGAFVA 185 >gi|119714486|ref|YP_921451.1| regulatory protein TetR [Nocardioides sp. JS614] gi|119535147|gb|ABL79764.1| transcriptional regulator, TetR family [Nocardioides sp. JS614] Length=211 Score = 76.6 bits (187), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 62/205 (31%), Positives = 106/205 (52%), Gaps = 13/205 (6%) Query 7 KKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMM 66 ++ +QG+ SR IL T + A +GY T++ + + GL SS+YWHF +K+ +LA + Sbjct 7 RRHRQGDESRHRILATTLEIAAERGYEGTTVGLVTERTGLPASSVYWHFKNKDELLAETL 66 Query 67 ERGAQRFFAAIPTWD--EAHGPVEQRSE--RQLTELVSLQSQHPDFLRLFYLLSME-RSQ 121 E +++ A PTW+ + G + R+E R+L + P+F RL +L++E R++ Sbjct 67 EYSYRQWREATPTWEGVDDEGVPDLRAEVRRRLRAASRALLESPEFWRLGLMLALERRAK 126 Query 122 DPAVAAVVRRVR---NTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFA 178 +PA VR AIAR+ S+ LP+++ + D + L +AL DG +F Sbjct 127 EPAARGRYVEVRLETAAAIARWWASV---LPAELRE-RDDELPDRLARVHLALMDG-FFV 181 Query 179 GHLEPDTTDVERMYRRLRQALEALI 203 G DV M + + + A + Sbjct 182 GRRADPRWDVGAMVELMAEGMAAYV 206 >gi|326333238|ref|ZP_08199485.1| LigA [Nocardioidaceae bacterium Broad-1] gi|325948882|gb|EGD40975.1| LigA [Nocardioidaceae bacterium Broad-1] Length=420 Score = 74.7 bits (182), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 57/187 (31%), Positives = 93/187 (50%), Gaps = 19/187 (10%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 K ++ SR+ IL+A RL A +GY T+++ +R A GL PSS+YWHF +K+ +LA Sbjct 4 KTLREHTHGSRQMILEAALRLAAERGYVGTTMALVRRATGLPPSSLYWHFPNKDQLLADA 63 Query 66 MERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQ----HPDFLRLFYLLSMERSQ 121 +E G R+ A+P W+E + R E L L S + D+ R+ +L++E Sbjct 64 LEHGYTRWHRAVPRWEETPRKGDLR-EGLLANLRRTTSDTRDANADWWRMGLMLALESG- 121 Query 122 DPAVAAVVR----RVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYF 177 P V R ++R +A F + + D+PP + L +A DG++ Sbjct 122 -PTVGDGPRQRFLQIRTQTLAGFELWWSGAV--DLPPAH----IETLARLTLAAHDGLFI 174 Query 178 AGHLEPD 184 H++ D Sbjct 175 --HVQTD 179 Score = 50.4 bits (119), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 34/111 (31%), Positives = 57/111 (52%), Gaps = 2/111 (1%) Query 15 SRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFF 74 SRE ++ A + A GY SIS I A L SS+YWHF +K+ + +A ++ + + Sbjct 227 SREKLVAAALEVAAESGYEGASISRICAAAKLPASSVYWHFANKDDLFSAAVDDSYRAWS 286 Query 75 AAIPTWDEAHGPVEQRSE--RQLTELVSLQSQHPDFLRLFYLLSMERSQDP 123 +A +W + +E R L LV+ + P FLR+ +L + + +P Sbjct 287 SAQSSWLPPSADCDWSTELPRMLKPLVASLRRLPPFLRIGLMLVLPKRPEP 337 >gi|298523775|ref|ZP_07011184.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298493569|gb|EFI28863.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=41 Score = 72.8 bits (177), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 35/35 (100%), Positives = 35/35 (100%), Gaps = 0/35 (0%) Query 143 SITHLLPSDIPPGKADLVVAELTAFAVALSDGVYF 177 SITHLLPSDIPPGKADLVVAELTAFAVALSDGVYF Sbjct 3 SITHLLPSDIPPGKADLVVAELTAFAVALSDGVYF 37 >gi|299534318|ref|ZP_07047662.1| TetR family transcriptional regulator [Comamonas testosteroni S44] gi|298717698|gb|EFI58711.1| TetR family transcriptional regulator [Comamonas testosteroni S44] Length=199 Score = 71.2 bits (173), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 64/195 (33%), Positives = 96/195 (50%), Gaps = 24/195 (12%) Query 27 MATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAH-- 84 MA +GYA T +S + +A GL S+IY HF SK G+L+ +M RGA+ FF A+ EAH Sbjct 1 MAERGYAGTPMSALVEATGLPKSAIYHHFESKAGLLSEVMARGARAFFDAM---REAHRE 57 Query 85 ----GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSM--ERSQDPAVAAVVRRVRNTAIA 138 G ++R L + + H DFLRL +L M E ++ P V +VR Sbjct 58 PPIDGSAQERLGWYLQKTGEVFVHHQDFLRLQLMLVMSNEAAEAPHAMETVIQVRTDG-- 115 Query 139 RFRDSITHLLPSDIPPGKADL--VVAE-LTAFAVALSDGVYFAGHLEPDTTDVERMYRRL 195 RD + ++ S +L +AE L F + DG + + T D M++ + Sbjct 116 --RDYMRVMIASAFCEEGEELASCIAEGLAHFGMVGFDGAF----VSVQTGDQRSMHQHM 169 Query 196 RQALEALIPVLLEET 210 Q +A+ VL+ ET Sbjct 170 EQLTQAM--VLMGET 182 >gi|56963375|ref|YP_175106.1| hypothetical protein ABC1610 [Bacillus clausii KSM-K16] gi|56909618|dbj|BAD64145.1| hypothetical protein [Bacillus clausii KSM-K16] Length=203 Score = 69.7 bits (169), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 37/128 (29%), Positives = 67/128 (53%), Gaps = 9/128 (7%) Query 15 SRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFF 74 +R +++A L A +GY T +SDI G+A + YWHF +KE ++ +++ G Q Sbjct 6 NRRHLMEAALALFAQEGYHKTKVSDIVKQVGVAQGTFYWHFKNKEEIVLCILQEGEQALL 65 Query 75 AAIPT-WDEAHGPVE---QRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVR 130 I + + + G V+ + S R +T+L S +PD++RL + ++ A + R Sbjct 66 NVIRSGYRQTEGNVDDMVESSRRLMTDLFSFAQANPDYMRLLF-----KTGQDAEEKICR 120 Query 131 RVRNTAIA 138 + +T IA Sbjct 121 HISHTLIA 128 >gi|295707078|ref|YP_003600153.1| TetR family transcriptional regulator [Bacillus megaterium DSM 319] gi|294804737|gb|ADF41803.1| transcriptional regulator, TetR family [Bacillus megaterium DSM 319] Length=290 Score = 68.9 bits (167), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 36/144 (25%), Positives = 69/144 (48%), Gaps = 7/144 (4%) Query 19 ILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIP 78 I++A+ +L A KG+ ATS+ +I D C ++ + Y HF SK+ +L +++ ++ F+++ Sbjct 8 IIEASIKLFAKKGFNATSVQEIVDECNISKGAFYLHFKSKDALLLSILNFYYEKLFSSVY 67 Query 79 TWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDP---AVAAVVRRVRNT 135 DE R QL ++H DF+ ++ + P V V +++ Sbjct 68 ALDEEVNDARSRYMNQLIYFYEFITEHRDFI----IMQIREKSIPFNKEVETFVHKMQRE 123 Query 136 AIARFRDSITHLLPSDIPPGKADL 159 R S+ + D+ P +DL Sbjct 124 TFYFHRKSLVSVYGEDVTPYISDL 147 >gi|317124915|ref|YP_004099027.1| TetR transcriptional regulator [Intrasporangium calvum DSM 43043] gi|315589003|gb|ADU48300.1| regulatory protein TetR [Intrasporangium calvum DSM 43043] Length=205 Score = 68.9 bits (167), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 50/157 (32%), Positives = 79/157 (51%), Gaps = 9/157 (5%) Query 4 PAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLA 63 P + + + ER + +L+ ER+ G+ AT++ DI + G+ IY +FGSKEG+LA Sbjct 6 PTRTRMPRAEREAQ-MLEVAERVFGANGFHATTMDDIAEQVGVTKPLIYDYFGSKEGLLA 64 Query 64 AMMERGAQRFFAAIPT-WD-EAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ 121 A +ER + A+ T WD +A +R +T + +H + F LL E S Sbjct 65 ATIERARHQLLDALITAWDSDAEAAPRERVAAVITAFFTFIDEHE---QAFALLRTEGSL 121 Query 122 DPAVAAVVRRVRNTAIARFRDSITHLLP--SDIPPGK 156 AA V R+R + IT +LP +D+ PG+ Sbjct 122 IGEAAASVERIRQQTAKALAEGIT-MLPEFADLAPGR 157 >gi|345442122|gb|AEN87139.1| putative transcriptional regulator YuxN [Bacillus megaterium WSH-002] Length=290 Score = 68.6 bits (166), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 36/146 (25%), Positives = 69/146 (48%), Gaps = 7/146 (4%) Query 17 ESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAA 76 + I++A +L A KG+ ATS+ +I D C ++ + Y HF SK+ +L +++ ++ F++ Sbjct 6 KKIIEAAIKLFAKKGFNATSVQEIVDECNISKGAFYLHFKSKDALLLSILNFYYEKLFSS 65 Query 77 IPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDP---AVAAVVRRVR 133 + DE R QL ++H DF+ ++ + P V V +++ Sbjct 66 VYALDEEVNDARSRYMNQLIYFYEFITEHRDFI----IMQIREKSIPFNKEVETFVHKMQ 121 Query 134 NTAIARFRDSITHLLPSDIPPGKADL 159 R S+ + D+ P +DL Sbjct 122 RETFYFHRKSLVSVYGEDVTPYISDL 147 >gi|294501731|ref|YP_003565431.1| TetR family transcriptional regulator [Bacillus megaterium QM B1551] gi|294351668|gb|ADE71997.1| transcriptional regulator, TetR family [Bacillus megaterium QM B1551] Length=290 Score = 67.8 bits (164), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 35/144 (25%), Positives = 69/144 (48%), Gaps = 7/144 (4%) Query 19 ILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIP 78 I++A+ +L A KG+ ATS+ +I D C ++ + Y HF SK+ +L +++ ++ F+++ Sbjct 8 IIEASIKLFAKKGFNATSVQEIVDECNISKGAFYLHFKSKDALLLSILNFYYEKLFSSVY 67 Query 79 TWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDP---AVAAVVRRVRNT 135 DE R QL ++H +F+ ++ + P V V +++ Sbjct 68 ALDEEVNDARSRYMNQLIYFYEFITEHRNFI----IMQIREKSIPFNKEVETFVHKMQRE 123 Query 136 AIARFRDSITHLLPSDIPPGKADL 159 R S+ + D+ P +DL Sbjct 124 TFYFHRKSLVSVYGEDVTPYISDL 147 >gi|332670780|ref|YP_004453788.1| regulatory protein TetR [Cellulomonas fimi ATCC 484] gi|332339818|gb|AEE46401.1| regulatory protein TetR [Cellulomonas fimi ATCC 484] Length=176 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/140 (32%), Positives = 76/140 (55%), Gaps = 9/140 (6%) Query 15 SRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFF 74 +R+ I+DA+ L+A +GY+ATS+ +I A G+A S++++FGSK + A++ G Q Sbjct 6 TRQRIVDASLALVADRGYSATSVDEIAAAAGVAKGSVFYNFGSKAELFEAILGEGVQHLT 65 Query 75 AAI-PTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVR 133 A + AHG + E +TEL++ HPDF ++ + + R QD +R +R Sbjct 66 ATLQGAAAGAHG--REAVEALVTELLTQVRDHPDFAKVM-VATGRRWQDS-----IRSLR 117 Query 134 NTAIARFRDSITHLLPSDIP 153 + A+ F ++ P P Sbjct 118 DDAMGVFAAAVRDAWPERDP 137 >gi|329938413|ref|ZP_08287838.1| A-factor receptor-like protein [Streptomyces griseoaurantiacus M045] gi|329302386|gb|EGG46277.1| A-factor receptor-like protein [Streptomyces griseoaurantiacus M045] Length=229 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 62/214 (29%), Positives = 96/214 (45%), Gaps = 31/214 (14%) Query 8 KQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMME 67 +Q + +RSRE IL A L GY T+++ + A GL S+YWHF +KE + A++E Sbjct 15 RQARSDRSREQILGAALDLAVVHGYQGTTMAAVSTASGLPIGSVYWHFKNKEQLFVALLE 74 Query 68 RGAQRFFAAIPTWDEAH-GPVEQRSERQLTE-LVSLQSQHPD-------FLRLFYLLSME 118 W E H GP R R+L+ + L P+ L+ + ++ Sbjct 75 H-------CYEVWKEVHSGPEGLR--RKLSRGIAGLSGADPEQYTKEEALLKAAAVWALS 125 Query 119 R-----SQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSD 173 R ++D V A R+R IT LP+D+ + V +LT ++AL+D Sbjct 126 RQLGGLAEDSEVRAAYLRMRAEMFGADVRRITESLPADVTRHFPE-VATKLTVMSLALTD 184 Query 174 GVYFAG----HLEPDTTDVERMYRRLRQALEALI 203 G Y HL+ D + + QALE L+ Sbjct 185 GFYVHANSEVHLDLDFGEYADL---AAQALEGLV 215 >gi|329121820|ref|ZP_08250436.1| hypothetical protein HMPREF9083_0898 [Dialister micraerophilus DSM 19965] gi|327468093|gb|EGF13581.1| hypothetical protein HMPREF9083_0898 [Dialister micraerophilus DSM 19965] Length=208 Score = 65.5 bits (158), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 29/101 (29%), Positives = 54/101 (54%), Gaps = 0/101 (0%) Query 10 QQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERG 69 ++GE+ ++ I+D T R++ +G+ +I I C +S+ ++FGSKE ++ A +E+ Sbjct 13 EKGEKIKQKIIDVTSRILRNEGFKKATIRRIAKECNTNIASVNYYFGSKEELIGAALEKM 72 Query 70 AQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLR 110 F A + D+ PV++R + + L QHP R Sbjct 73 IFNFEAIVSYLDKTDLPVKERLRKYILGYFKLAHQHPALFR 113 >gi|313892658|ref|ZP_07826244.1| transcriptional regulator, TetR family [Dialister microaerophilus UPII 345-E] gi|313118918|gb|EFR42124.1| transcriptional regulator, TetR family [Dialister microaerophilus UPII 345-E] Length=203 Score = 65.5 bits (158), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 29/101 (29%), Positives = 54/101 (54%), Gaps = 0/101 (0%) Query 10 QQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERG 69 ++GE+ ++ I+D T R++ +G+ +I I C +S+ ++FGSKE ++ A +E+ Sbjct 8 EKGEKIKQKIIDVTSRILRNEGFKKATIRRIAKECNTNIASVNYYFGSKEELIGAALEKM 67 Query 70 AQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLR 110 F A + D+ PV++R + + L QHP R Sbjct 68 IFNFEAIVSYLDKTDLPVKERLRKYILGYFKLAHQHPALFR 108 >gi|337746243|ref|YP_004640405.1| TetR family transcriptional regulator [Paenibacillus mucilaginosus KNP414] gi|336297432|gb|AEI40535.1| transcriptional regulator, TetR family [Paenibacillus mucilaginosus KNP414] Length=199 Score = 64.7 bits (156), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 29/62 (47%), Positives = 41/62 (67%), Gaps = 0/62 (0%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 KKQQQ E++++ I DA L A KGY AT+I DI A G + +IY+HF +KEG+ + Sbjct 2 NKKQQQTEQTKKKIADAARVLFAQKGYKATAIEDIVKAAGCSAGNIYYHFKNKEGLFLYL 61 Query 66 ME 67 +E Sbjct 62 LE 63 >gi|251799080|ref|YP_003013811.1| TetR family transcriptional regulator [Paenibacillus sp. JDR-2] gi|247546706|gb|ACT03725.1| transcriptional regulator, TetR family [Paenibacillus sp. JDR-2] Length=199 Score = 64.7 bits (156), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 38/99 (39%), Positives = 52/99 (53%), Gaps = 8/99 (8%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 KKQQQ E+++ I DA L KGY ATSI DI A G + +IY+HF SKEG+ + Sbjct 2 NKKQQQTEQTKRKIADAARTLFVQKGYKATSIEDIVKATGCSAGNIYYHFKSKEGLFLHL 61 Query 66 ME----RGAQRFFAAIP----TWDEAHGPVEQRSERQLT 96 +E + + A P T D+ +G E + QL Sbjct 62 IEDWNTEWEETWLAKEPQYKTTIDKLYGMAEHLAHDQLN 100 >gi|334337205|ref|YP_004542357.1| regulatory protein TetR [Isoptericola variabilis 225] gi|334107573|gb|AEG44463.1| regulatory protein TetR [Isoptericola variabilis 225] Length=227 Score = 64.7 bits (156), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 56/169 (34%), Positives = 83/169 (50%), Gaps = 17/169 (10%) Query 13 ERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQR 72 E RE IL L A +GYAATS+ DI +A ++ + + HFGSKE + + +++R QR Sbjct 17 EDKRERILQEAFALFAERGYAATSLRDIAEAAEISKAGVLHHFGSKEAIYSEVLDRRDQR 76 Query 73 FFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSME--RSQDPAVAAV-- 128 F + +D G ER + ELV S P +RL+ ++++ + PA + Sbjct 77 DFVGMEAFD---GDTWAFLERWV-ELVEHNSGQPAMVRLYSAMAVDGVDADHPAHQWLHQ 132 Query 129 --VRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGV 175 VR V+ TA R ++ SD P EL VALSDG+ Sbjct 133 HFVRAVQETAAVFERGKGLGVVHSDAPS-------RELARTIVALSDGI 174 >gi|315443504|ref|YP_004076383.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315261807|gb|ADT98548.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=208 Score = 64.7 bits (156), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 53/192 (28%), Positives = 90/192 (47%), Gaps = 11/192 (5%) Query 8 KQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMME 67 +Q++ + +R +LDA E ++A +G+ A ++ I DA G +IY HFG+KE + A+ME Sbjct 7 RQRRVDHTRALLLDAAEEVVARQGFGAAALEVIADAAGYTRGAIYAHFGTKEELFLAVME 66 Query 68 RGAQRFFAAIPTWDEAHGPVEQRS-ERQLTELVSLQSQHPDFLRLFYLLSMERSQDP-AV 125 R QRF E+ +E+ +R L +PD L Y ++ ++P A Sbjct 67 RQLQRFLDGFTDIVESFRSLEEMDVDRLAGRWRELTIGNPDRAALGYEFTLFLVRNPEAR 126 Query 126 AAVVRRVRNTAIARFRDSITHLLPSDIPP--GKADLVVAELTAFAVALSDGVYFAGHLEP 183 V + R TA DS+ + + G+ + L +A +G+ GH+ Sbjct 127 VRVAEQRRRTA-----DSLAEYISVHVEKIGGRLRIPAPTLARILIATYEGITLGGHI-- 179 Query 184 DTTDVERMYRRL 195 D D+ R + L Sbjct 180 DGEDLARTFLEL 191 >gi|62860884|gb|AAY16477.1| transcriptional regulator [Bifidobacterium breve] gi|339478556|gb|ABE95011.1| Transcriptional regulator, TetR family [Bifidobacterium breve UCC2003] Length=224 Score = 63.9 bits (154), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 52/201 (26%), Positives = 95/201 (48%), Gaps = 16/201 (7%) Query 13 ERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQR 72 E R+SI++A + +KG A ++ ++ D G+ + + +FGSK G+L A++ R Sbjct 16 EERRQSIIEAAADVFGSKGTANGTLQEVADRVGMTRAGVLHYFGSKRGLLEAVLR---NR 72 Query 73 FFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMER--SQDPAVAAVVR 130 + + +D+ H P ++ R L E L + P+ +R F LS E +P Sbjct 73 DSSEVAEFDQGHLPRGAQAFRHLVETAELNASRPNVVRTFVTLSAESVTENNPGNTYFHE 132 Query 131 R---VRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTD 187 R +RN R +D + + D+ KA+ A + +A+ DG+ ++ D D Sbjct 133 RYDGLRNELKERMQD-MADEMGRDLDEEKAEAACASI----IAVMDGLQLQWLIDKDHID 187 Query 188 VERMYRRLRQALEALIPVLLE 208 M + A++ALI V+ + Sbjct 188 ---MPSTVDFAIKALIAVVFD 205 >gi|336428636|ref|ZP_08608615.1| hypothetical protein HMPREF0994_04621 [Lachnospiraceae bacterium 3_1_57FAA_CT1] gi|336005016|gb|EGN35068.1| hypothetical protein HMPREF0994_04621 [Lachnospiraceae bacterium 3_1_57FAA_CT1] Length=209 Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 37/97 (39%), Positives = 54/97 (56%), Gaps = 6/97 (6%) Query 13 ERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQ- 71 E++ E I+D + L A KGY TSI DI DA GL+ +Y HF SKE +L A+M++ Q Sbjct 8 EQTLEKIVDVSAELFAKKGYEQTSIQDILDATGLSKGGLYHHFKSKEEILEAVMQKRVQY 67 Query 72 ---RFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQH 105 RF I +E + +++ +R L +L S H Sbjct 68 VNGRFHNIIRNTEETNA--KEKLKRILYQLASDMETH 102 >gi|145223048|ref|YP_001133726.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145215534|gb|ABP44938.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=234 Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 53/192 (28%), Positives = 90/192 (47%), Gaps = 11/192 (5%) Query 8 KQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMME 67 +Q++ + +R +LDA E ++A +G+ A ++ I DA G +IY HFG+KE + A+ME Sbjct 33 RQRRVDHTRALLLDAAEEVVARQGFGAAALEVIADAAGYTRGAIYAHFGTKEELFLAVME 92 Query 68 RGAQRFFAAIPTWDEAHGPVEQRS-ERQLTELVSLQSQHPDFLRLFYLLSMERSQDP-AV 125 R QRF E+ +E+ +R L +PD L Y ++ ++P A Sbjct 93 RQLQRFLDGFTDIVESFRSLEEMDVDRLAGRWRELTIGNPDRAALGYEFTLFLVRNPEAR 152 Query 126 AAVVRRVRNTAIARFRDSITHLLPSDIPP--GKADLVVAELTAFAVALSDGVYFAGHLEP 183 V + R TA DS+ + + G+ + L +A +G+ GH+ Sbjct 153 VRVAEQRRRTA-----DSLAEYISVHVEKIGGRLRIPAPTLARILIATYEGITLGGHI-- 205 Query 184 DTTDVERMYRRL 195 D D+ R + L Sbjct 206 DGEDLARPFLEL 217 >gi|336320465|ref|YP_004600433.1| regulatory protein TetR [Cellvibrio gilvus ATCC 13127] gi|336104046|gb|AEI11865.1| regulatory protein TetR [Cellvibrio gilvus ATCC 13127] Length=178 Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 43/144 (30%), Positives = 72/144 (50%), Gaps = 13/144 (9%) Query 15 SRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFF 74 +R I++A L+A +G +ATS+ +I A G+A S++++FGSK G++ ++ G R Sbjct 4 TRRQIVEAALGLVADRGISATSVDEIAAAAGVAKGSVFYNFGSKAGLIEEILAEGVARLT 63 Query 75 AAIPTWDEAHGPVEQRS--ERQLTELVSLQSQHPDFLRLFYLLSMERS---QDPAVAAVV 129 AA+ EA +E R+ E +T L+ HPDF ++ S QD + Sbjct 64 AAL---QEAAAGLEGRAALEAMVTALLQQIHAHPDFSKVIVAESFRTGRLWQDS-----I 115 Query 130 RRVRNTAIARFRDSITHLLPSDIP 153 R+VR ++ F + P P Sbjct 116 RQVREESMGTFTTVVAQAWPQRDP 139 >gi|226314645|ref|YP_002774541.1| transcriptional regulator [Brevibacillus brevis NBRC 100599] gi|226097595|dbj|BAH46037.1| probable transcriptional regulator [Brevibacillus brevis NBRC 100599] Length=199 Score = 63.2 bits (152), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 29/62 (47%), Positives = 41/62 (67%), Gaps = 0/62 (0%) Query 6 KKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAM 65 KK+QQ E++++ I DA+ L KGY ATSI DI A G + +IY+HF SKEG+ + Sbjct 2 NKKKQQTEQTKKKIADASRILFMQKGYKATSIEDIVKATGYSGGNIYYHFKSKEGLFLHL 61 Query 66 ME 67 +E Sbjct 62 IE 63 >gi|336176474|ref|YP_004581849.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata] gi|334857454|gb|AEH07928.1| regulatory protein TetR [Frankia symbiont of Datisca glomerata] Length=194 Score = 62.8 bits (151), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 48/152 (32%), Positives = 77/152 (51%), Gaps = 15/152 (9%) Query 16 RESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA 75 R+SI+DAT L+A +GY S+++I G+A S+IYWHF SK+ +L + ++ R A Sbjct 12 RQSIIDATAELLARRGYGGVSMAEIGAEVGIAASAIYWHFPSKQDLLVELFDQCLDRLRA 71 Query 76 AIPTWDEAHGPVEQ--RSERQLTELVSLQSQ----HPDFLRLFYLLSMERSQDPAVAAVV 129 E G VE+ R+ L E+ LQ + F R++Y ER+ A + Sbjct 72 ------EQVGAVERLGRTREALIEIARLQVEFVVRQRAFARVYY--QEERNLRDADLVRL 123 Query 130 RRVRNTAIARFRDSITHLLPSDIPPGKADLVV 161 R + + + D + L P D+ P A+ +V Sbjct 124 RGKQRAYVETWTDLLLSLRP-DLDPVSAECLV 154 Lambda K H 0.320 0.133 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 245963417238 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40