BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0303

Length=302
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607444|ref|NP_214817.1|  dehydrogenase/reductase [Mycobacter...   614    4e-174
gi|289760412|ref|ZP_06519790.1|  oxidoreductase [Mycobacterium tu...   612    3e-173
gi|326906058|gb|EGE52991.1|  dehydrogenase/reductase [Mycobacteri...   611    4e-173
gi|254230672|ref|ZP_04923999.1|  hypothetical protein TBCG_00299 ...   542    3e-152
gi|289748787|ref|ZP_06508165.1|  dehydrogenase/reductase [Mycobac...   429    2e-118
gi|126658757|ref|ZP_01729902.1|  probable dehydrogenase/reductase...   258    1e-66 
gi|172054974|ref|YP_001806301.1|  glucose/ribitol short chain deh...   254    1e-65 
gi|145228893|ref|XP_001388755.1|  short-chain dehydrogenase [Aspe...   234    1e-59 
gi|290987756|ref|XP_002676588.1|  predicted protein [Naegleria gr...   220    2e-55 
gi|336118094|ref|YP_004572862.1|  oxidoreductase [Microlunatus ph...   216    5e-54 
gi|290979894|ref|XP_002672668.1|  predicted protein [Naegleria gr...   206    3e-51 
gi|212539179|ref|XP_002149745.1|  short-chain dehydrogenase, puta...   205    6e-51 
gi|134098190|ref|YP_001103851.1|  light-dependent protochlorophyl...   203    3e-50 
gi|290981036|ref|XP_002673237.1|  predicted protein [Naegleria gr...   199    5e-49 
gi|124005259|ref|ZP_01690100.1|  retinol dehydrogenase 13 [Micros...   199    6e-49 
gi|334337197|ref|YP_004542349.1|  short-chain dehydrogenase/reduc...   196    4e-48 
gi|39974903|ref|XP_368842.1|  hypothetical protein MGG_00402 [Mag...   192    4e-47 
gi|242760774|ref|XP_002340057.1|  short-chain dehydrogenase, puta...   187    2e-45 
gi|269118990|ref|YP_003307167.1|  short-chain dehydrogenase/reduc...   169    4e-40 
gi|291240714|ref|XP_002740281.1|  PREDICTED: WW domain-containing...   166    3e-39 
gi|296130684|ref|YP_003637934.1|  short-chain dehydrogenase/reduc...   162    5e-38 
gi|289434386|ref|YP_003464258.1|  glucose/ribitol dehydrogenase f...   161    1e-37 
gi|307152599|ref|YP_003887983.1|  light-dependent protochlorophyl...   159    4e-37 
gi|313633763|gb|EFS00505.1|  glucose/ribitol short chain dehydrog...   157    1e-36 
gi|290972817|ref|XP_002669147.1|  predicted protein [Naegleria gr...   153    3e-35 
gi|82582335|sp|Q5F389.2|WWOX_CHICK  RecName: Full=WW domain-conta...   152    5e-35 
gi|224063789|ref|XP_002197346.1|  PREDICTED: WW domain-containing...   148    9e-34 
gi|41053891|ref|NP_957207.1|  WW domain-containing oxidoreductase...   148    1e-33 
gi|242039231|ref|XP_002467010.1|  hypothetical protein SORBIDRAFT...   146    4e-33 
gi|256824413|ref|YP_003148373.1|  short-chain alcohol dehydrogena...   146    5e-33 
gi|302543101|ref|ZP_07295443.1|  short-chain dehydrogenase/reduct...   145    5e-33 
gi|255078496|ref|XP_002502828.1|  light-dependent protochlorophyl...   145    5e-33 
gi|46019982|emb|CAD99008.1|  NADPH-protochlorophyllide oxidoreduc...   145    6e-33 
gi|194697158|gb|ACF82663.1|  unknown [Zea mays]                        145    7e-33 
gi|293337123|ref|NP_001167680.1|  protochlorophyllide reductase B...   145    7e-33 
gi|15218860|ref|NP_171860.1|  protochlorophyllide reductase C [Ar...   145    1e-32 
gi|79316418|ref|NP_001030948.1|  protochlorophyllide reductase C ...   144    1e-32 
gi|154313450|ref|XP_001556051.1|  hypothetical protein BC1G_05422...   144    1e-32 
gi|10720236|sp|Q42850.1|PORB_HORVU  RecName: Full=Protochlorophyl...   144    1e-32 
gi|75248671|sp|Q8W3D9.1|PORB_ORYSJ  RecName: Full=Protochlorophyl...   144    1e-32 
gi|284814268|gb|ADB97492.1|  NADPH-protochlorophyllide oxidoreduc...   144    2e-32 
gi|226500452|ref|NP_001149903.1|  protochlorophyllide reductase B...   144    2e-32 
gi|297843168|ref|XP_002889465.1|  por C [Arabidopsis lyrata subsp...   143    3e-32 
gi|31980962|ref|NP_062519.2|  WW domain-containing oxidoreductase...   142    7e-32 
gi|332846578|ref|XP_001144696.2|  PREDICTED: WW domain-containing...   142    9e-32 
gi|289157495|gb|ADC84385.1|  WW domain-containing oxidoreductase ...   142    9e-32 
gi|221130525|ref|XP_002161049.1|  PREDICTED: similar to WW domain...   141    1e-31 
gi|284042392|ref|YP_003392732.1|  Protochlorophyllide reductase [...   141    1e-31 
gi|118151256|ref|NP_001071560.1|  WW domain-containing oxidoreduc...   141    1e-31 
gi|334313155|ref|XP_001368394.2|  PREDICTED: WW domain-containing...   141    1e-31 


>gi|15607444|ref|NP_214817.1| dehydrogenase/reductase [Mycobacterium tuberculosis H37Rv]
 gi|15839688|ref|NP_334725.1| short chain dehydrogenase/reductase family oxidoreductase [Mycobacterium 
tuberculosis CDC1551]
 gi|31791482|ref|NP_853975.1| dehydrogenase/reductase [Mycobacterium bovis AF2122/97]
 73 more sequence titles
 Length=302

 Score =  614 bits (1584),  Expect = 4e-174, Method: Compositional matrix adjust.
 Identities = 302/302 (100%), Positives = 302/302 (100%), Gaps = 0/302 (0%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV  60
            MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV
Sbjct  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV  60

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120
            DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV
Sbjct  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120

Query  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS  180
            TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS
Sbjct  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS  180

Query  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240
            KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP
Sbjct  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240

Query  241  FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
            FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ
Sbjct  241  FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300

Query  301  VT  302
            VT
Sbjct  301  VT  302


>gi|289760412|ref|ZP_06519790.1| oxidoreductase [Mycobacterium tuberculosis GM 1503]
 gi|289707918|gb|EFD71934.1| oxidoreductase [Mycobacterium tuberculosis GM 1503]
Length=302

 Score =  612 bits (1577),  Expect = 3e-173, Method: Compositional matrix adjust.
 Identities = 301/302 (99%), Positives = 301/302 (99%), Gaps = 0/302 (0%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV  60
            MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPAR RAAMEELGEPNRCSVLEV
Sbjct  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARDRAAMEELGEPNRCSVLEV  60

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120
            DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV
Sbjct  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120

Query  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS  180
            TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS
Sbjct  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS  180

Query  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240
            KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP
Sbjct  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240

Query  241  FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
            FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ
Sbjct  241  FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300

Query  301  VT  302
            VT
Sbjct  301  VT  302


>gi|326906058|gb|EGE52991.1| dehydrogenase/reductase [Mycobacterium tuberculosis W-148]
Length=302

 Score =  611 bits (1576),  Expect = 4e-173, Method: Compositional matrix adjust.
 Identities = 301/302 (99%), Positives = 301/302 (99%), Gaps = 0/302 (0%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV  60
            MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV
Sbjct  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEV  60

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120
            DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV
Sbjct  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120

Query  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS  180
            TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS
Sbjct  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTS  180

Query  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240
            KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP
Sbjct  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240

Query  241  FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
            FVHSTRVSGE LAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ
Sbjct  241  FVHSTRVSGEDLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300

Query  301  VT  302
            VT
Sbjct  301  VT  302


>gi|254230672|ref|ZP_04923999.1| hypothetical protein TBCG_00299 [Mycobacterium tuberculosis C]
 gi|124599731|gb|EAY58741.1| hypothetical protein TBCG_00299 [Mycobacterium tuberculosis C]
Length=303

 Score =  542 bits (1396),  Expect = 3e-152, Method: Compositional matrix adjust.
 Identities = 279/313 (90%), Positives = 280/313 (90%), Gaps = 21/313 (6%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEEL-----------  49
            MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGR     +           
Sbjct  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRGGHGGIGGAKPVFGSRG  60

Query  50   GEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTF  109
            G   RC             RSFVE VRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTF
Sbjct  61   GTSRRCG----------PWRSFVEIVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTF  110

Query  110  GVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNT  169
            GVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNT
Sbjct  111  GVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNT  170

Query  170  PAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAY  229
            PAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAY
Sbjct  171  PAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAY  230

Query  230  RLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALD  289
            RLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALD
Sbjct  231  RLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALD  290

Query  290  LWETSERLLAQVT  302
            LWETSERLLAQVT
Sbjct  291  LWETSERLLAQVT  303


>gi|289748787|ref|ZP_06508165.1| dehydrogenase/reductase [Mycobacterium tuberculosis T92]
 gi|289689374|gb|EFD56803.1| dehydrogenase/reductase [Mycobacterium tuberculosis T92]
Length=209

 Score =  429 bits (1104),  Expect = 2e-118, Method: Compositional matrix adjust.
 Identities = 208/209 (99%), Positives = 209/209 (100%), Gaps = 0/209 (0%)

Query  94   VVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPR  153
            +VSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPR
Sbjct  1    MVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPR  60

Query  154  YTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMP  213
            YTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMP
Sbjct  61   YTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMP  120

Query  214  GSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAK  273
            GSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAK
Sbjct  121  GSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAK  180

Query  274  AIRSSAESYDRAKALDLWETSERLLAQVT  302
            AIRSSAESYDRAKALDLWETSERLLAQVT
Sbjct  181  AIRSSAESYDRAKALDLWETSERLLAQVT  209


>gi|126658757|ref|ZP_01729902.1| probable dehydrogenase/reductase [Cyanothece sp. CCY0110]
 gi|126620019|gb|EAZ90743.1| probable dehydrogenase/reductase [Cyanothece sp. CCY0110]
Length=318

 Score =  258 bits (658),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 139/307 (46%), Positives = 187/307 (61%), Gaps = 16/307 (5%)

Query  5    TAVITGASSGLGLQCARAL-LRRDASWHVVLAVRDPARGRAAMEEL---GEPNRCSVLEV  60
            T +I+GA++GLG  CA+ L L +D   ++VLA R+  +   A+E+L      N+   + +
Sbjct  3    TVIISGANNGLGYACAKELALNKDI--YLVLACRNKEKAEKAVEQLKNLSNNNQIEAIIL  60

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120
            DLAS++SVR F        LPP+R ++CNAG+Q +    +T+DG+E TF VNHLGHF LV
Sbjct  61   DLASLQSVRQFEAEFAQKNLPPLRIIICNAGVQFIQRRTYTEDGMETTFAVNHLGHFLLV  120

Query  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAE-----GRR  175
              +L  L  P RI+ VSS THDPSK TGMP P +     LAHP  D     +     GR 
Sbjct  121  NLLLKHLKSPGRIIFVSSDTHDPSKITGMPAPNFQDPDLLAHPELDSTLKDKSASDIGRT  180

Query  176  RYTTSKLCNVLFTYELDRRLDHG-----EQGVMVNAFDPGLMPGSGLARDYPPILRLAYR  230
             YTTSKLCN+L  YEL RRL+       E  + VN F PGLMPG+GLA+DYPP+ ++ + 
Sbjct  181  AYTTSKLCNILCAYELSRRLEKQGLSTEEHPITVNVFSPGLMPGTGLAQDYPPLAKIVWD  240

Query  231  LLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDL  290
             + P+    P ++S + SG+ LA L  DP    VTG+YF+G + I SS ESYD  KA  L
Sbjct  241  YILPLFSFFPKINSPQQSGQALAKLVEDPLLRQVTGKYFSGLQMIESSQESYDVEKARQL  300

Query  291  WETSERL  297
            W+ S  L
Sbjct  301  WDKSLEL  307


>gi|172054974|ref|YP_001806301.1| glucose/ribitol short chain dehydrogenase/reductase family protein 
[Cyanothece sp. ATCC 51142]
 gi|171701255|gb|ACB54235.1| glucose/ribitol short chain dehydrogenase/reductase family protein 
[Cyanothece sp. ATCC 51142]
Length=318

 Score =  254 bits (648),  Expect = 1e-65, Method: Compositional matrix adjust.
 Identities = 141/308 (46%), Positives = 189/308 (62%), Gaps = 16/308 (5%)

Query  5    TAVITGASSGLGLQCARAL-LRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLE---V  60
            T +I+GA++GLG  CA+ L L +D   ++VLA RD  +   A+E+L    + + +E   +
Sbjct  3    TVIISGANNGLGYACAKELALNKDI--YLVLACRDNEKATKAVEKLKNTTKNNQIEYICL  60

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALV  120
            DLAS++SVR F        LPP+  ++CNAG+Q +    +TDDG+E TF VNHLGHF LV
Sbjct  61   DLASLQSVRQFEAKFAQKNLPPLGIIICNAGVQFIQRRTYTDDGMETTFAVNHLGHFLLV  120

Query  121  TGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHP---PT--DQNTPAEGRR  175
              +L  L  P RI+ VSS THDPSK TGMP P +     LA P   PT  D+     GR 
Sbjct  121  NLLLKHLKPPGRIIFVSSDTHDPSKITGMPPPNFQDPNLLARPELDPTLKDKGVSDLGRI  180

Query  176  RYTTSKLCNVLFTYELDRRLDHG-----EQGVMVNAFDPGLMPGSGLARDYPPILRLAYR  230
             YTTSKLCN+L  YEL RRLD       E  + VN F PGLMPG+GLA+DYPP+ ++ + 
Sbjct  181  AYTTSKLCNILCAYELSRRLDKQRLSTEEHPITVNVFTPGLMPGTGLAQDYPPLAKIVWD  240

Query  231  LLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDL  290
             + P+    P +++ + SG  LA L  DP+   VTG+YF+G + I SS ESYD  KA  L
Sbjct  241  YILPLFSFFPKINTPQQSGRALARLVEDPQLKNVTGKYFSGLQMIESSQESYDVEKAQQL  300

Query  291  WETSERLL  298
            W+ S  L+
Sbjct  301  WDKSVELV  308


>gi|145228893|ref|XP_001388755.1| short-chain dehydrogenase [Aspergillus niger CBS 513.88]
 gi|134054847|emb|CAK43687.1| unnamed protein product [Aspergillus niger]
Length=324

 Score =  234 bits (598),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 134/306 (44%), Positives = 185/306 (61%), Gaps = 15/306 (4%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAM--EELGEPNRCSVLEVDLAS  64
            +ITG ++GLG  C   L R+   + V++A R  +R  A    + LG+ N  S L +DL+ 
Sbjct  8    LITGGTAGLGYYCTIELARQFPDYQVIIASRSDSRDAAGSINKLLGQSN-VSYLRLDLSD  66

Query  65   VRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGIL  124
            +  VRSFV+   T   PPI+ L+ NAGLQ    + +T DG E TF +NH+GH  L + ++
Sbjct  67   LSKVRSFVQQWETNKYPPIQYLLLNAGLQFPGPVEYTVDGYEKTFAINHIGHALLFSLLV  126

Query  125  DWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCN  184
              LA  ARIVV SSGTHDP++ TG+PD +YT A DLAH PT  +    GR+RY+TSKL N
Sbjct  127  PHLANTARIVVTSSGTHDPAQETGLPDAKYTSAEDLAH-PTKSSAQNPGRQRYSTSKLAN  185

Query  185  VLFTYELDRRLDHGE----QGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLS----PML  236
            V++ Y L RRL   +    +   V AFDPGLMPG+GL R+  P+LR  + ++     P+L
Sbjct  186  VIWVYALHRRLSESKDARLKSWTVVAFDPGLMPGTGLVREANPVLRFLWHVIFPRVIPLL  245

Query  237  RVL---PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWET  293
            RV+   P +   + SG +LA LA     +  +G Y+ G K IRSS ESYD  K  DLW+ 
Sbjct  246  RVMLGTPNIRLPQASGANLAWLASGKEASSSSGVYYEGRKQIRSSEESYDVNKQDDLWDW  305

Query  294  SERLLA  299
            + R +A
Sbjct  306  TVRNVA  311


>gi|290987756|ref|XP_002676588.1| predicted protein [Naegleria gruberi]
 gi|284090191|gb|EFC43844.1| predicted protein [Naegleria gruberi]
Length=352

 Score =  220 bits (560),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 130/332 (40%), Positives = 183/332 (56%), Gaps = 41/332 (12%)

Query  5    TAVITGASSGLGLQCARALLRRD-----ASWHVVLAVRDPARGRAAME------------  47
            + +ITG +SG+GL+  R LLR +      + H+V+A R      + ME            
Sbjct  11   SVIITGCNSGIGLEAVRQLLREEWDSNRKTKHIVMACRGVELSNSEMETFIQDYLKEHPE  70

Query  48   --ELGEPNRCSVLEVDLASVRSVRSFVETVRT----TPLPPIRALVCNAGLQVVSGIAFT  101
              E    ++ + L++DLAS +S+  FV  +++    + +PP+ +LVCNAGLQ  + +  T
Sbjct  71   RNETELKSQITALKLDLASFKSIHQFVSEIKSLIDSSKIPPLHSLVCNAGLQYANKLVLT  130

Query  102  DDGVEMTFGVNHLGHFALVTGILDWLARPA----RIVVVSSGTHDPSKHTGMPDPRYTCA  157
            ++G E TFGVNHLGHF L+  +L    +      RIV+VSS THD +K TGMP P +  A
Sbjct  131  EEGYEATFGVNHLGHFLLINLLLPLFTKSTNSKNRIVIVSSDTHDRTKFTGMPVPEFETA  190

Query  158  ADLAHPPTDQNTPAE----GRRRYTTSKLCNVLFTYELDRRLDHG---EQGVMVNAFDPG  210
              LA   TD +T  +    GR RYTTSK CN+L  YEL  RL           VN+F+PG
Sbjct  191  EKLAIISTDSDTEQDNSKLGRVRYTTSKFCNILCAYELVTRLQSHPIYRDQFTVNSFNPG  250

Query  211  LMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHS----TRVSGEHLAALAVDPRFAGVTG  266
             +P +GL+RDY   LR   R + P+LR   FVHS      VSG  L  L +D     VTG
Sbjct  251  FVPTTGLSRDYNKFLRAIARNVLPLLR---FVHSGVRTLEVSGYDLKQLIIDRNLENVTG  307

Query  267  QYFAGAKAIRSSAESYDRAKALDLWETSERLL  298
            +YF G+  I SS ++Y+     +LWE S +L+
Sbjct  308  KYFDGSNMIDSSPDTYNTTIQNELWEDSIKLI  339


>gi|336118094|ref|YP_004572862.1| oxidoreductase [Microlunatus phosphovorus NM-1]
 gi|334685874|dbj|BAK35459.1| oxidoreductase [Microlunatus phosphovorus NM-1]
Length=304

 Score =  216 bits (549),  Expect = 5e-54, Method: Compositional matrix adjust.
 Identities = 136/303 (45%), Positives = 174/303 (58%), Gaps = 15/303 (4%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE---PNRCSVLEVD  61
            T +ITGAS+GLG + A  L    A   ++L VRDP +G+  + +L           +  D
Sbjct  3    TILITGASAGLGRETAVRLT--SAGHRILLVVRDPVKGQRVVADLRARQLDTGSEAITCD  60

Query  62   LASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVT  121
            LA + SVRS    +      PI  ++CNAG+Q+V+G A + DG E+TF VNHL HF LVT
Sbjct  61   LADLGSVRSLAGQL-IARKEPIDTVICNAGVQIVNGPARSADGYELTFAVNHLAHFLLVT  119

Query  122  GILDWLARPARIVVVSSGTH-DPSKHTGMPDPRYTCAADLA--HPPTDQN-TPAEGRR--  175
             +LD L RP+R++++ SG H  PS+  G P P +     LA     TDQ+  P  GR   
Sbjct  120  ELLDHLRRPSRVIMIGSGVHLGPSRSFGFPAPEWAEPRQLALADQLTDQSGVPTSGRVGR  179

Query  176  -RYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSP  234
             RY  SKL N++F YEL RR   GE  V VNAFDPGLMP +GLAR YP  +R  YR L+ 
Sbjct  180  VRYANSKLANIMFAYELARRTVDGE--VTVNAFDPGLMPQTGLARQYPAPIRQLYRYLTS  237

Query  235  MLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETS  294
            +L +LP  H    S   LA LA  P   GV+G+YF   +A  SSA SYD   AL LWE S
Sbjct  238  LLTLLPGAHRVSKSAADLAWLATAPELTGVSGKYFVERRARPSSALSYDGGLALQLWEQS  297

Query  295  ERL  297
              L
Sbjct  298  TAL  300


>gi|290979894|ref|XP_002672668.1| predicted protein [Naegleria gruberi]
 gi|284086246|gb|EFC39924.1| predicted protein [Naegleria gruberi]
Length=313

 Score =  206 bits (525),  Expect = 3e-51, Method: Compositional matrix adjust.
 Identities = 126/312 (41%), Positives = 176/312 (57%), Gaps = 23/312 (7%)

Query  5    TAVITGASSGLGLQCARALLR-RDASWHVVLAVRDPARGRAAMEELGE-----PNRCSVL  58
            T ++TGA+ GLG +  + LL  +   WHVVLA RD ++G+ A++++ E      +R + +
Sbjct  7    TVIVTGANCGLGFESTKYLLSDKIDEWHVVLACRDESKGKQAIQQIVEIDQEYASRLTFI  66

Query  59   EVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFA  118
            E+DLA + SVR+FV       LPP++AL+CNA  Q    I+ T  G ++ FGVNHLGHF 
Sbjct  67   ELDLADLDSVRNFVTNFNQEKLPPLKALICNAATQAPPNISTTKQGYDIVFGVNHLGHFL  126

Query  119  LVTGILDWLARPAR---IVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRR  175
            L   ++   A+      IV V+S THDP   T +P P Y     L  PP  Q TP     
Sbjct  127  LTNLLIPHFAKNDEINSIVNVTSDTHDPKNGTPVPVPTYGPVDKLIIPP--QETPKRD-S  183

Query  176  RYTTSKLCNVLFTYELDRRLDHGEQ---GVMVNAFDPGLMPGSGLARDY-PPILRLAYRL  231
            RY TSKLCN+LFTYEL  RLD  ++      VN F+PG MP + LAR   P +  +    
Sbjct  184  RYATSKLCNILFTYELKNRLDKSDEFKNHFRVNCFNPGFMPETSLARYLDPKLFNMIVEG  243

Query  232  LSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVT-GQYFAGAKAIRSSAESYDRAKALDL  290
                 R  P  +S+R    +LA L V+P+   V+ G Y+ G + I SS ESY+ +K L+L
Sbjct  244  EGKKYRK-PIANSSR----YLADL-VNPQLDKVSNGVYYDGNEIIPSSDESYEVSKQLEL  297

Query  291  WETSERLLAQVT  302
            WE S+ L+   T
Sbjct  298  WEGSKNLIKTET  309


>gi|212539179|ref|XP_002149745.1| short-chain dehydrogenase, putative [Penicillium marneffei ATCC 
18224]
 gi|210069487|gb|EEA23578.1| short-chain dehydrogenase, putative [Penicillium marneffei ATCC 
18224]
Length=327

 Score =  205 bits (522),  Expect = 6e-51, Method: Compositional matrix adjust.
 Identities = 119/305 (40%), Positives = 172/305 (57%), Gaps = 12/305 (3%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVR-DPARGRAAMEELGEPNRCSVLEVDLASV  65
            +ITG ++ LG QC   L R+   + +V+A R +P     ++  L        L +DL+S+
Sbjct  10   LITGGTANLGYQCTINLARKYPDYQIVIASRSNPNSSAESINRLLGQKNVEFLPLDLSSL  69

Query  66   RSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILD  125
              VR+FV         PI +LV NA LQ    + +TDDG E TF ++H+GH  L + +  
Sbjct  70   AQVRTFVVQWEAGQFLPIYSLVFNAALQFPGDVQYTDDGFEKTFAISHIGHALLFSLLRP  129

Query  126  WLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCNV  185
             LA  AR+ +VSSGTHDP++ TG+PD  Y+ A +LAHP  D      GR+RY T+KL NV
Sbjct  130  HLADTARVAIVSSGTHDPAQKTGLPDAYYSSAEELAHPKGDA-LKTNGRQRYATTKLTNV  188

Query  186  LFTYELDRRLDHGEQGV----MVNAFDPGLMPGSGLARDYPPILRLAYR----LLSPMLR  237
            L++Y L RR +   +       V A DPGLMPG+GLARD     R  +      + P+LR
Sbjct  189  LYSYALHRRFEAINKKTGKHWTVAAIDPGLMPGTGLARDATGFERFLWLKVLPKIIPLLR  248

Query  238  VL--PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSE  295
            +L  P +H+T  SG+ LA L         +G+Y+   + I+SS  SYD+ K  DLW+ + 
Sbjct  249  LLISPNIHTTEHSGKMLARLVTGSDEEIGSGKYYEEDRQIKSSDASYDQDKQEDLWKWTI  308

Query  296  RLLAQ  300
            + LA+
Sbjct  309  KTLAK  313


>gi|134098190|ref|YP_001103851.1| light-dependent protochlorophyllide reductase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|291009118|ref|ZP_06567091.1| light-dependent protochlorophyllide reductase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|133910813|emb|CAM00926.1| light-dependent protochlorophyllide reductase [Saccharopolyspora 
erythraea NRRL 2338]
Length=300

 Score =  203 bits (516),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 144/305 (48%), Positives = 184/305 (61%), Gaps = 13/305 (4%)

Query  3    TGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE--PN-RCSVLE  59
            T   VITGASSGLG   A  +       HVVLA RD  RG AA +E+    P+    VLE
Sbjct  2    TERVVITGASSGLGQAAAEEVA--ATGRHVVLACRDADRGAAAADEIRARVPDASLEVLE  59

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFAL  119
            +DLA + SVR+  + +   P  P+ ALVCNAG+QVV GI  + DG E+TF  NHLGHF L
Sbjct  60   LDLADLASVRAAAKALLAGP--PLGALVCNAGVQVVGGIRRSRDGHELTFATNHLGHFLL  117

Query  120  VTGILDWLARPARIVVVSSGTH-DPSKHTGMPDPRYTCAADLAHPPTD--QNTPAEGRRR  176
               +LD LA   RIV+VSSGTH  P +  G P P +   + LA P      ++P  GR R
Sbjct  118  TRLLLDHLAEAGRIVLVSSGTHYGPRRSMGFPAPHWENPSALADPELSVLDDSPRSGRIR  177

Query  177  YTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPML  236
            Y TSKL N+  TYEL+RR +   + + VNAFDPGLMP +GLARDYP   R  Y  ++P+L
Sbjct  178  YATSKLANIYTTYELNRRRNG--RRITVNAFDPGLMPQTGLARDYPDRFRRLYGRIAPVL  235

Query  237  -RVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSE  295
             R +P V S   S   L+ L        V+G YF G +  ++S ESYDR +AL+LWE SE
Sbjct  236  VRAVPGVRSVARSAADLSWLVTAGEPGVVSGLYFVGRRPRKTSDESYDRVRALELWEFSE  295

Query  296  RLLAQ  300
            RL+++
Sbjct  296  RLVSE  300


>gi|290981036|ref|XP_002673237.1| predicted protein [Naegleria gruberi]
 gi|284086819|gb|EFC40493.1| predicted protein [Naegleria gruberi]
Length=351

 Score =  199 bits (505),  Expect = 5e-49, Method: Compositional matrix adjust.
 Identities = 124/332 (38%), Positives = 180/332 (55%), Gaps = 41/332 (12%)

Query  5    TAVITGASSGLGLQCARALLRRD-----ASWHVVLAVRDPARGRAAMEELGE------PN  53
            + +ITG +SG+GL+ AR +LR +      + H+V+A R      + M+   +      P 
Sbjct  11   SVIITGCNSGIGLEAARQMLREEWDSNRKTKHLVMACRGVELSNSEMDAFVQDYLKEHPE  70

Query  54   R--------CSVLEVDLASVRSVRSFVETVRT----TPLPPIRALVCNAGLQVVSGIAFT  101
            R         + L++DLAS +S++ FV  +++    + +PP+ +LVCNAG+  V  +  T
Sbjct  71   RNESELKGQITALKLDLASFKSIQQFVSELKSLIDNSKIPPLHSLVCNAGVSFVHKLILT  130

Query  102  DDGVEMTFGVNHLGHFALVTGILDWLARPA----RIVVVSSGTHDPSKHTGMPDPRYTCA  157
            ++G E TFGVNHLGHF L+  +L    +      RIV+VSS  H   K  GMP P +  A
Sbjct  131  EEGYEATFGVNHLGHFLLINLLLPLFTKSTNSKNRIVIVSSDIHGRKKFGGMPAPEFETA  190

Query  158  ADLAHPPTDQNTPAE----GRRRYTTSKLCNVLFTYELDRRLDHGE---QGVMVNAFDPG  210
              LA  PTD NT  +    G  RYTTSK CNVL  YEL  RL   +       VN ++PG
Sbjct  191  EKLAIIPTDSNTDQDNSKFGSVRYTTSKFCNVLCAYELITRLQSRQIYRDQFTVNLYNPG  250

Query  211  LMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHS----TRVSGEHLAALAVDPRFAGVTG  266
             +P + L+RDY  +LR   R + P+LR   FVHS      VSG  L  L VD     VTG
Sbjct  251  FVPTTSLSRDYNKVLRSIARNVLPLLR---FVHSGVRTLEVSGGDLKQLIVDRNLDSVTG  307

Query  267  QYFAGAKAIRSSAESYDRAKALDLWETSERLL  298
            +YF G + + S+ ++Y+     +LW+ S +L+
Sbjct  308  KYFDGREIVDSAPDTYNTRLQNELWDDSIKLI  339


>gi|124005259|ref|ZP_01690100.1| retinol dehydrogenase 13 [Microscilla marina ATCC 23134]
 gi|123989081|gb|EAY28659.1| retinol dehydrogenase 13 [Microscilla marina ATCC 23134]
Length=304

 Score =  199 bits (505),  Expect = 6e-49, Method: Compositional matrix adjust.
 Identities = 118/300 (40%), Positives = 164/300 (55%), Gaps = 15/300 (5%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEP---NRCSVLEVD  61
            T ++TGA+SGLGL  ++ LL +D +  VVLA R+  +   A + L +     R  +  +D
Sbjct  3    TVIVTGANSGLGLYTSKHLLLQDYA--VVLACRNLKKAAKAQKWLHKKTGKKRTKIAHLD  60

Query  62   LASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVT  121
            LAS   +R F      TPL  +  +VCNAG+       FT DG+E TFGVNHLGHF LV 
Sbjct  61   LASFNHIRKFC---LNTPLNNVYGVVCNAGISYAHPTRFTQDGIEETFGVNHLGHFLLVN  117

Query  122  GILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQ--NTPAEGRRRYTT  179
             +L       RI VVSS  H+P      P P Y  A +LA+P   +  N   EG  RY  
Sbjct  118  LLLGKAQNLQRIAVVSSDAHNPDIQGYHPPPYYERALELAYPDDSRVINWEKEGALRYAN  177

Query  180  SKLCNVLFTYELDRRLDHGE-QGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPML-R  237
            SKLCNVLF Y L   L     Q ++VNAF+PG +PG+GL ++  P+ +  +  + P+  R
Sbjct  178  SKLCNVLFVYHLAEELKKTHRQHILVNAFNPGFIPGTGLGKNSSPVSKFLWFNVLPLFSR  237

Query  238  VLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERL  297
                + +   SG+ LA+L  +   A  +G+Y+ G K   SS +SYD+ +A  LW  SE L
Sbjct  238  FSKAIRTANESGKALASLISE---ANASGKYYDGFKEKPSSKQSYDKKQAQKLWWRSEEL  294


>gi|334337197|ref|YP_004542349.1| short-chain dehydrogenase/reductase SDR [Isoptericola variabilis 
225]
 gi|334107565|gb|AEG44455.1| short-chain dehydrogenase/reductase SDR [Isoptericola variabilis 
225]
Length=319

 Score =  196 bits (498),  Expect = 4e-48, Method: Compositional matrix adjust.
 Identities = 145/305 (48%), Positives = 178/305 (59%), Gaps = 11/305 (3%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE---PNRCSV  57
            M   T VITGA+SGLGL  AR L +R   WHVV+  RD ARG AA E++       R   
Sbjct  1    MPDSTVVITGATSGLGLHTARRLAQR--GWHVVMGHRDAARGAAAAEDVRRRVPGARVEA  58

Query  58   LEVDLASVRSVRSFVETVRT--TPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLG  115
            + +DLA++RSV   VE +R    P PP+RA+V N  +QVV G+  + DG E+TF  NHLG
Sbjct  59   MHIDLAALRSVSRAVELLRDGGAPRPPLRAIVANGAVQVVDGVRTSADGYELTFATNHLG  118

Query  116  HFALVTGILDWLARPARIVVVSSGTH-DPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGR  174
            H  LVT +LD L   AR+VVVSSGTH  P +  G P PR+    +LA P     +   GR
Sbjct  119  HHHLVTSLLDHLGPAARVVVVSSGTHWGPERALGFPGPRWRDPVELADPRRADASATAGR  178

Query  175  RRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSP  234
             RY TSKL N+LF  EL RR     + +  NAFDPGLMPG+ LARDY P  R AYRLL+P
Sbjct  179  VRYATSKLANLLFVRELARR--SAGRRIAANAFDPGLMPGTALARDYAPAARAAYRLLAP  236

Query  235  MLRVL-PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWET  293
             +  L P   + R S   LA +    RF GVTG Y AG     SS  S+   +A  LWE 
Sbjct  237  AVAALVPGAGTARRSSATLADMVDSRRFEGVTGAYVAGRTLAESSPLSHSADEARLLWEA  296

Query  294  SERLL  298
            S  L+
Sbjct  297  SRALV  301


>gi|39974903|ref|XP_368842.1| hypothetical protein MGG_00402 [Magnaporthe oryzae 70-15]
 gi|145018707|gb|EDK02986.1| hypothetical protein MGG_00402 [Magnaporthe oryzae 70-15]
Length=325

 Score =  192 bits (489),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 126/306 (42%), Positives = 173/306 (57%), Gaps = 16/306 (5%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVR---DPARGRAAMEELGEPNRCSVLEVDLA  63
            +ITG ++G+G   A  + +      +V+A R   D A G A  + L + N    L +DLA
Sbjct  9    IITGGTAGMGFAAATQMAKDCPDHLIVIASRSSNDDAAG-AINKSLNQSN-TQFLPIDLA  66

Query  64   SVRSVRSFV-ETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTG  122
            +   VR F  + +     PPI+ALV NA LQ  +G+  T DG+E TF + H GH  L   
Sbjct  67   NPTDVRRFARDWMADESKPPIKALVFNAALQFPNGLTLTPDGMEKTFAIAHAGHALLFHL  126

Query  123  ILDWLA-RPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSK  181
            +   L  R AR+V+ SSGTHDP++ +GMPDP YT AA +A+PP ++      R  YTT+K
Sbjct  127  LFPRLVPRGARVVLTSSGTHDPAQRSGMPDPVYTTAAQVAYPPPER-AALPSRAHYTTAK  185

Query  182  LCNVLFTYELDRRLDHG--EQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSP----M  235
            LCNVL+ Y L R L     E+ V V A DPGLMPG+GLAR+   + R  +  + P    +
Sbjct  186  LCNVLWAYALARHLGDAVPERSVSVTAMDPGLMPGTGLARETTRVQRWLWVAVLPRLLWL  245

Query  236  LRVL--PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWET  293
            LR++  P VH+   SG  LA LAV     GVTG+YF G + I SS +SY      DLW+ 
Sbjct  246  LRMVFSPNVHTAEESGRSLARLAVGADVEGVTGRYFEGREEIMSSKDSYSEKLQEDLWDW  305

Query  294  SERLLA  299
            +   +A
Sbjct  306  TVNFVA  311


>gi|242760774|ref|XP_002340057.1| short-chain dehydrogenase, putative [Talaromyces stipitatus ATCC 
10500]
 gi|218723253|gb|EED22670.1| short-chain dehydrogenase, putative [Talaromyces stipitatus ATCC 
10500]
Length=316

 Score =  187 bits (475),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 112/293 (39%), Positives = 161/293 (55%), Gaps = 19/293 (6%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVR-DPARGRAAMEELGEPNRCSVLEVDLA  63
            + +ITG +SGLG  CA  + R+   + +++A R DP     A+           L +DL+
Sbjct  8    SILITGGTSGLGYHCALNVARKYPDYQIIIASRSDPNSSANALNNALNQKNVRFLPLDLS  67

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGI  123
            S+           T   PPI +LV NA LQ    + ++ DG E TF ++H+GH  L + +
Sbjct  68   SL-------AQWETNQFPPIHSLVFNAALQFPGDVQYSIDGFEKTFAISHIGHALLFSLL  120

Query  124  LDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLC  183
               LA  AR+V+VSSGTHDP++ +GMPD  Y+ A +LAH PT Q+    GR+RY+T+KL 
Sbjct  121  RPHLADMARVVIVSSGTHDPAQKSGMPDAYYSSAGELAH-PTGQSLKNNGRQRYSTTKLV  179

Query  184  NVLFTYELDRRLD----HGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVL  239
            NVL+ Y L RR +       +   V AFDPG MPG+GLARDY  + R  +  + P +  L
Sbjct  180  NVLYGYALHRRFEAINKKSGKHWTVAAFDPGFMPGTGLARDYSALQRFLWLKVLPKILPL  239

Query  240  PF------VHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAK  286
                     H+   SG+ LA L ++      +G Y+ G K I+SS  SYD+ K
Sbjct  240  LRLLLTPNTHTVEHSGKMLARLVIESDEEIGSGAYYEGPKRIKSSDASYDQDK  292


>gi|269118990|ref|YP_003307167.1| short-chain dehydrogenase/reductase SDR [Sebaldella termitidis 
ATCC 33386]
 gi|268612868|gb|ACZ07236.1| short-chain dehydrogenase/reductase SDR [Sebaldella termitidis 
ATCC 33386]
Length=294

 Score =  169 bits (429),  Expect = 4e-40, Method: Compositional matrix adjust.
 Identities = 105/295 (36%), Positives = 155/295 (53%), Gaps = 24/295 (8%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEEL---GEPNRCSVLEVD  61
            T +ITGA+SGLG +CA+ +L  +  + +V+A R   +   +  EL    +    +V+E++
Sbjct  3    TIIITGANSGLGFECAKNILLENPGYFIVMACRSIEKAEKSKSELIKMTKNENIAVMELN  62

Query  62   LASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVT  121
            L+S+ SVR F E  +    PP+  +VCNAG+   S +  T+DG ++ FG NHLGHF L  
Sbjct  63   LSSLNSVRKFAENFKQAGYPPLFGIVCNAGISN-SNVGVTEDGFDIVFGTNHLGHFLLTV  121

Query  122  GILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSK  181
             +L  +    RI VVSS  H+P    G+    Y  A +LAHP +  N        Y+ SK
Sbjct  122  LLLPLVEENGRITVVSSDMHNPP--NGLT---YRGAEELAHPASKINDI------YSQSK  170

Query  182  LCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSP--MLRVL  239
            LCN+ FTYEL  RL    + + VNAF+PGL+  +    +       + R  S   M +V 
Sbjct  171  LCNLYFTYELAGRLSEMGRKITVNAFNPGLLTDTNFHVN-------STRSFSEDFMKKVA  223

Query  240  PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETS  294
              +     SG+ LA +   P +   TG+Y    + I SS  SY+   A  LWE+S
Sbjct  224  DRIGYLSESGKALADMVTKPYYGENTGKYNDRGEEIPSSELSYNAENAKKLWESS  278


>gi|291240714|ref|XP_002740281.1| PREDICTED: WW domain-containing oxidoreductase-like [Saccoglossus 
kowalevskii]
Length=319

 Score =  166 bits (421),  Expect = 3e-39, Method: Compositional matrix adjust.
 Identities = 120/303 (40%), Positives = 162/303 (54%), Gaps = 17/303 (5%)

Query  6    AVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE--PN-RCSVLEVDL  62
             VITGA++G+G + A+ +   +  + V+LA R   RG  A+  L    P+ RC  ++ DL
Sbjct  16   CVITGANTGIGFESAKIMA--EMGYDVILACRSKTRGEDAIRRLNTMIPDARCQFIKCDL  73

Query  63   ASVRSVRSFVETVRTTPLPPIRALVCNAGLQV-VSGIAFTDDGVEMTFGVNHLGHFALVT  121
            AS+ S+++FV+    T   P+  L  NAGL   + G   TDDG EMT GVNHLGHF L  
Sbjct  74   ASLESIQNFVDEFHATG-KPLHVLCNNAGLTTQMIGRLETDDGFEMTMGVNHLGHFLLTH  132

Query  122  GILDWLAR------PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRR  175
             +LD L R       AR++V +S  HDP    G   P+     D  +   D+     G  
Sbjct  133  LLLDDLKRTAKDCGEARVIVTTSKLHDPESMGGRKGPK--AHMDFQNLQLDKQGTFSGVL  190

Query  176  RYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPM  235
             Y  +KL NVLFTYEL RRL HG  GV  N F PG +  + L R +    +    LLSP+
Sbjct  191  AYKNAKLANVLFTYELARRL-HG-TGVTCNCFHPGFIATTELFRHFGWPFKAMMYLLSPL  248

Query  236  LRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSE  295
            LR    + S +  GE ++ LA DP   GV+G+YF   +   SS ESYD   A  LW+ SE
Sbjct  249  LRWFGAIRSLQHGGEMVSFLATDPSLKGVSGKYFENFREESSSTESYDENVATKLWKISE  308

Query  296  RLL  298
             L+
Sbjct  309  ELV  311


>gi|296130684|ref|YP_003637934.1| short-chain dehydrogenase/reductase SDR [Cellulomonas flavigena 
DSM 20109]
 gi|296022499|gb|ADG75735.1| short-chain dehydrogenase/reductase SDR [Cellulomonas flavigena 
DSM 20109]
Length=301

 Score =  162 bits (411),  Expect = 5e-38, Method: Compositional matrix adjust.
 Identities = 110/267 (42%), Positives = 146/267 (55%), Gaps = 11/267 (4%)

Query  32   VVLAVRDPARGRAAMEELGEPNRCSVLEV---DLASVRSVRSFVETVRTTPLPPIRALVC  88
            +VL VRD ARG A   EL      ++++V   DLA + SVR+    +    +P +RA+VC
Sbjct  29   LVLVVRDVARGEALAGEL-RTTWGALVDVRGADLADLASVRALAGALVRDDVP-LRAVVC  86

Query  89   NAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHT-  147
            NAG+QV+ G+  + DG E+T   N LGH AL+  +L  L   AR+V + S TH   +   
Sbjct  87   NAGVQVLDGVRRSPDGYELTAAANVLGHVALLAPLLTRLRPGARVVTLGSETHRGGRRAF  146

Query  148  GMPDPRYTCAADLAHPPTDQ-NTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNA  206
            G P  R+  AA L  PP D    P  GR RY+TSKL  +    ELD R    E GV   A
Sbjct  147  GFPAARWVDAATLLDPPLDAPGDPGSGRVRYSTSKLACIALARELDAR----EGGVRAVA  202

Query  207  FDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTG  266
            +DPGLMP +GLARDYPP++R  Y  L+P+L  LP     R S E LA LA DP    + G
Sbjct  203  YDPGLMPETGLARDYPPVVRRVYAALTPLLVRLPGARRVRDSAEDLAWLATDPAAEPLMG  262

Query  267  QYFAGAKAIRSSAESYDRAKALDLWET  293
             Y +G ++   S  +       D+W T
Sbjct  263  GYVSGRRSHAPSPTALRADVGADVWST  289


>gi|289434386|ref|YP_003464258.1| glucose/ribitol dehydrogenase family protein [Listeria seeligeri 
serovar 1/2b str. SLCC3954]
 gi|289170630|emb|CBH27170.1| glucose/ribitol dehydrogenase family protein [Listeria seeligeri 
serovar 1/2b str. SLCC3954]
Length=302

 Score =  161 bits (407),  Expect = 1e-37, Method: Compositional matrix adjust.
 Identities = 102/301 (34%), Positives = 151/301 (51%), Gaps = 25/301 (8%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEP---NRCSV  57
            MN  T +ITG +SGLG   A+ +  R   + ++LA R+  +   A+ EL +         
Sbjct  3    MNKKTIMITGGNSGLGFAAAKIIASRYKDYQLILACRNLEKANMAVNELQKSTDNQNIIA  62

Query  58   LEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHF  117
            +E+D++S+ SVR FV   +   L  +  ++CNAG+   +    T DG ++ F  NHLGHF
Sbjct  63   MELDVSSLHSVRKFVANFQAADLGLLDGILCNAGING-NNTGLTKDGFDVVFETNHLGHF  121

Query  118  ALVTGILDWLARPARIVVVSSGTHDPSKHT----GMPDPRYTCAADLAHPPTDQNTPAEG  173
             L   ++ ++    RIVVVSS  H+P        G+P         LA+P    NT    
Sbjct  122  LLTNLLVPFMREDGRIVVVSSDMHNPPGDNLTWPGVPA--------LAYPSESLNTHF--  171

Query  174  RRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLS  233
              RY+ SKLCN+ FTY L  +L + +  + VNAF+PGL+  +  A   P   R       
Sbjct  172  -IRYSYSKLCNLYFTYSLVEKLAYMKSKITVNAFNPGLLTTTNFA---PDKSRFTEEF--  225

Query  234  PMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWET  293
             M ++   + +  VS E LA L  D ++  VTG+YF     I SS  SYD     +LW+ 
Sbjct  226  -MKQIEDRIGTLEVSSEALANLMTDSKYDYVTGKYFDRGVEILSSPLSYDENNRTELWKK  284

Query  294  S  294
            S
Sbjct  285  S  285


>gi|307152599|ref|YP_003887983.1| light-dependent protochlorophyllide reductase [Cyanothece sp. 
PCC 7822]
 gi|306982827|gb|ADN14708.1| light-dependent protochlorophyllide reductase [Cyanothece sp. 
PCC 7822]
Length=326

 Score =  159 bits (403),  Expect = 4e-37, Method: Compositional matrix adjust.
 Identities = 111/321 (35%), Positives = 176/321 (55%), Gaps = 30/321 (9%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEP-NRCSVLEVDLA  63
            TA+ITGASSG+GLQ A+AL   D  W+VV+A RD  + +   +E+G P +  +++ +DLA
Sbjct  8    TAIITGASSGVGLQAAKAL--ADLGWYVVMACRDIEKTKRVAQEVGMPADSYNIIYIDLA  65

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHFALVT  121
            S++SVR FV+  R     P+ ALVCNA +   ++    ++ DG E+T   NHLGHF L  
Sbjct  66   SLQSVREFVKYFRALSR-PLDALVCNAAIYMPLLKEPLWSPDGYELTMATNHLGHFLLCN  124

Query  122  GILDWL----ARPARIVVVSSGTHDPSKHTGMPDPR------YTCAADLAHPPTDQNTPA  171
             +LD L     +PA++V++ + TH+P++  G   PR         AA    P +  +  A
Sbjct  125  LMLDDLKQSAVKPAKLVILGTVTHNPNELGGKIPPRPDLGNLQGFAAGFKAPYSMIDGKA  184

Query  172  -EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYR  230
             E  + Y  SK+CN+L   EL RR  H   G++ N+  PG +  + L R++ P  +  + 
Sbjct  185  FEPVKAYKDSKVCNILTMRELHRRY-HASTGIIFNSLYPGCVATTALFRNHYPKFQKYFP  243

Query  231  LLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESY--------  282
            L    +    FV S  +SG+ +A +  +P FA  +G Y++     + + +++        
Sbjct  244  LFQKYI-TGGFV-SEELSGQRVAQVVAEPDFAQ-SGVYWSWGNRQKKNGQAFVQKVSTQA  300

Query  283  -DRAKALDLWETSERLLAQVT  302
             D AKA+ LWE SE+L+   T
Sbjct  301  GDDAKAVRLWELSEQLVGLKT  321


>gi|313633763|gb|EFS00505.1| glucose/ribitol short chain dehydrogenase/reductase family protein 
[Listeria seeligeri FSL N1-067]
Length=302

 Score =  157 bits (398),  Expect = 1e-36, Method: Compositional matrix adjust.
 Identities = 100/300 (34%), Positives = 150/300 (50%), Gaps = 25/300 (8%)

Query  2    NTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEP---NRCSVL  58
            N  T +ITG +SGLG   A+ +  R   + ++LA R+  +   A+ EL +         +
Sbjct  4    NKKTIMITGGNSGLGFAAAKIIASRYKDYQLILACRNLEKANMAVNELQKSTDNQNIIAM  63

Query  59   EVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFA  118
            E+D++S+ SVR FV   +   L  +  ++CNAG+   +    T DG ++ F  NHLGHF 
Sbjct  64   ELDVSSLHSVRKFVANFQAADLGLLDGILCNAGING-NNTGLTKDGFDVVFETNHLGHFL  122

Query  119  LVTGILDWLARPARIVVVSSGTHDPSKHT----GMPDPRYTCAADLAHPPTDQNTPAEGR  174
            L   ++ ++    RIV+VSS  H+P        G+P         LA+P    NT     
Sbjct  123  LTNLLVPFMREDGRIVLVSSDMHNPPGDNLTWPGVPA--------LAYPSESLNTHF---  171

Query  175  RRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSP  234
             RY+ SKLCN+ FTY L  +L + +  + VNAF+PGL+  +  A   P   R        
Sbjct  172  IRYSYSKLCNLYFTYSLVEKLAYMKSKITVNAFNPGLLTTTNFA---PDKSRFTEEF---  225

Query  235  MLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETS  294
            M ++   + +  VS E LA L  D ++  VTG+YF     I SS  SYD     +LW+ S
Sbjct  226  MKQIEDRIGTLEVSSEALANLMTDSKYDYVTGKYFDRGVEILSSPLSYDENNRTELWKKS  285


>gi|290972817|ref|XP_002669147.1| predicted protein [Naegleria gruberi]
 gi|284082690|gb|EFC36403.1| predicted protein [Naegleria gruberi]
Length=231

 Score =  153 bits (386),  Expect = 3e-35, Method: Compositional matrix adjust.
 Identities = 93/226 (42%), Positives = 128/226 (57%), Gaps = 15/226 (6%)

Query  1    MNTG--TAVITGASSGLGLQCARALLRRDA-SWHVVLAVRDPARGRAAMEEL---GEPNR  54
            +N G  T ++TGA+ GLG +CA+ L   +   WHVVLA RD +RG+ A+E +      +R
Sbjct  5    LNRGKRTVIVTGANCGLGFECAKQLFADEKLEWHVVLACRDESRGKEALETILNGSVSDR  64

Query  55   CSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHL  114
             S++ +DL+ + SVR FV+   +  LPP++ALV NAG+     +  T  G E+T GVNH+
Sbjct  65   ISLILLDLSDLESVRKFVKEFESAKLPPLKALVANAGIVAPPKLTLTKQGYEITVGVNHI  124

Query  115  GHFALVTGILDWLARPAR----IVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTP  170
            GHF L   +L    R  +    I VVSS  HDP     MP  +Y     L  PP +  TP
Sbjct  125  GHFLLTNLLLPLFERDQKEINSIAVVSSEVHDPKLKIPMPKAKYDSIEKLISPPYE--TP  182

Query  171  AEGRRRYTTSKLCNVLFTYELDRRLDHGEQ---GVMVNAFDPGLMP  213
             E   RY TSKL N+LFTYEL +RL +  +      V  F+PG +P
Sbjct  183  EEIGSRYPTSKLLNILFTYELWKRLQNSSEFKNQFRVTCFNPGFIP  228


>gi|82582335|sp|Q5F389.2|WWOX_CHICK RecName: Full=WW domain-containing oxidoreductase
Length=414

 Score =  152 bits (385),  Expect = 5e-35, Method: Compositional matrix adjust.
 Identities = 108/299 (37%), Positives = 155/299 (52%), Gaps = 24/299 (8%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE---PNRCSVLEVDLA  63
            +ITGA+SG+G + A++     A  +V+LA R+ +RG  A++ + E     +   + +DLA
Sbjct  128  IITGANSGIGFETAKSFALHGA--YVILACRNMSRGNDAVQRILEEWHKAKVEAMTLDLA  185

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGI  123
            S+RSV++F E  ++  +P +  LVCNA +   S    T+DG+E TF VNHLGHF LV  +
Sbjct  186  SLRSVQNFAEAFKSKNMP-LHILVCNAAI-FGSSWCLTEDGLESTFQVNHLGHFYLVQLL  243

Query  124  LDWLAR--PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSK  181
             D L R  PAR+VVVSS +H   + T + D        L  P   +         Y  SK
Sbjct  244  EDILRRSSPARVVVVSSESH---RFTEIKDSSGKLDFSLLSPSKKEYWAMLA---YNRSK  297

Query  182  LCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPF  241
            LCN+LF+ EL+RRL     GV  N+  PG M  S + R++       Y LL  + R  PF
Sbjct  298  LCNILFSNELNRRL--SPHGVTSNSVHPGNMIYSSIHRNW-----WVYTLLFTLAR--PF  348

Query  242  VHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
              S +         A      G+ G YF        SAE+ +   A+ LWE SERL+ +
Sbjct  349  TKSMQQGAATTVYCATAAELEGLGGMYFNNCCRCLPSAEARNELTAVALWELSERLIRE  407


>gi|224063789|ref|XP_002197346.1| PREDICTED: WW domain-containing oxidoreductase [Taeniopygia guttata]
Length=414

 Score =  148 bits (374),  Expect = 9e-34, Method: Compositional matrix adjust.
 Identities = 111/299 (38%), Positives = 157/299 (53%), Gaps = 24/299 (8%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEE-LGEPNRCSV--LEVDLA  63
            +ITGA+SG+G + A++L    A   V+LA R PARG AA++  LGE ++  V  + +DLA
Sbjct  128  IITGANSGIGFETAKSLALHGAC--VILACRSPARGEAAVQRILGEWHKAKVEAMTLDLA  185

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGI  123
            S++SV+ F E  ++  LP +  L+CNA +   +  + T+DG+E TF VNHLGHF LV  +
Sbjct  186  SLQSVQHFAEAFKSKNLP-LHILICNAAV-FGAPWSLTEDGLESTFQVNHLGHFYLVQLL  243

Query  124  LDWL--ARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSK  181
             D L  + PAR+VVVSS +H   + T + D        L  PP  +         Y  SK
Sbjct  244  EDVLRQSSPARVVVVSSESH---RFTEIKDSSGKLDFSLLSPPKKEYW---AMLAYNRSK  297

Query  182  LCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPF  241
            LCN+LF+ EL+RRL     GV  N+  PG M  S + R++       Y LL  + R  PF
Sbjct  298  LCNILFSNELNRRL--SPHGVTSNSVHPGNMIYSSIHRNW-----WLYTLLFTLAR--PF  348

Query  242  VHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
              S +         A      G+ G YF        S ++   A A  LWE SE L+ +
Sbjct  349  TKSMQQGAATTVYCATAAELEGLGGMYFNNCCRCLPSQQAQADATAAALWELSESLIQE  407


>gi|41053891|ref|NP_957207.1| WW domain-containing oxidoreductase [Danio rerio]
 gi|82210113|sp|Q803A8.1|WWOX_DANRE RecName: Full=WW domain-containing oxidoreductase
 gi|27881987|gb|AAH44560.1| WW domain containing oxidoreductase [Danio rerio]
Length=412

 Score =  148 bits (373),  Expect = 1e-33, Method: Compositional matrix adjust.
 Identities = 113/299 (38%), Positives = 154/299 (52%), Gaps = 24/299 (8%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARG-RAAMEELGEPN--RCSVLEVDLA  63
            ++TGA+SG+G + AR+     A  HV+LA R+ +R  +AA   +GE +  R  VL +DLA
Sbjct  125  IVTGANSGIGFETARSFALHGA--HVILACRNQSRASKAASLIMGEWSKARVEVLPLDLA  182

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGI  123
            S+RSVR F E  + T LP +  LVCNA +        T+DG E TF + HLGHF LV  +
Sbjct  183  SLRSVRQFAELFKATKLP-LHVLVCNAAV-CSQPWRLTEDGFESTFQICHLGHFLLVQLL  240

Query  124  LDW--LARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSK  181
             D   L+ PAR+VVVSS +H   + T + D       DL  PP            Y  +K
Sbjct  241  QDVLRLSAPARVVVVSSESH---RFTDLLDSCGNLDLDLLSPPQKNYWSLLA---YNRAK  294

Query  182  LCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPF  241
            LCN+LF+ EL RR+     G+  NA  PG M  + + R +  +L L + L        PF
Sbjct  295  LCNLLFSSELHRRM--SPHGICCNALHPGSMMFTSIHRSWW-LLTLLFSL------ARPF  345

Query  242  VHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
              S +         AV P   G+ G YF        S ++ D A AL LWE SERL+ +
Sbjct  346  TKSMQQGAATTVYCAVAPELEGIGGMYFNNCFRCLPSPQAQDPAAALSLWELSERLVQE  404


>gi|242039231|ref|XP_002467010.1| hypothetical protein SORBIDRAFT_01g018230 [Sorghum bicolor]
 gi|241920864|gb|EER94008.1| hypothetical protein SORBIDRAFT_01g018230 [Sorghum bicolor]
Length=394

 Score =  146 bits (369),  Expect = 4e-33, Method: Compositional matrix adjust.
 Identities = 112/321 (35%), Positives = 161/321 (51%), Gaps = 31/321 (9%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLE  59
            +  GTAVITGASSGLGL  A+AL      WHV++A RD  +   A +  G + +  +++ 
Sbjct  79   LRKGTAVITGASSGLGLATAKAL-AETGKWHVIMACRDFLKASRAAKAAGMDKDSFTIVH  137

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHF  117
            +DLAS+ SVR FV+ VR   +P I  +VCNA +        ++T DG EM+ GVNHLGHF
Sbjct  138  LDLASLDSVRQFVKNVRQLEMP-IDVVVCNAAVYQPTAKDPSYTADGFEMSVGVNHLGHF  196

Query  118  ALVTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPA--  171
             L   +L  L        R+++V S T + +   G   P+     DL       N     
Sbjct  197  LLARELLSDLQSSDYPSKRLIIVGSITGNTNTLAGNVPPKANL-GDLRGLAGGLNGIGSS  255

Query  172  --------EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPP  223
                    +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P
Sbjct  256  VMIDGGEFDGAKAYKDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIP  314

Query  224  ILRLAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----  277
            + RL   L  P  + +   + S   +G+ LA +  DP     +G Y++  K   S     
Sbjct  315  LFRL---LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLTK-SGVYWSWNKNSASFENQL  370

Query  278  SAESYDRAKALDLWETSERLL  298
            S E+ D  KA  LWE SE+L+
Sbjct  371  SEEASDSDKAKKLWEISEKLV  391


>gi|256824413|ref|YP_003148373.1| short-chain alcohol dehydrogenase like protein [Kytococcus sedentarius 
DSM 20547]
 gi|256687806|gb|ACV05608.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase 
like protein [Kytococcus sedentarius DSM 20547]
Length=320

 Score =  146 bits (368),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 117/308 (38%), Positives = 157/308 (51%), Gaps = 20/308 (6%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEEL-GEPNRCSVLEVDLA  63
            T V+TGAS G+G   AR LL      H+VL  R   +  A ++EL       +V+  DL+
Sbjct  6    TVVMTGASRGIGRTAARRLLAGRPQAHLVLLSRTVPQ--ALVDELRAAGGSVTVIRADLS  63

Query  64   SVRSVRS----FVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFAL  119
            S+RSV       VE V    LPPI ALVCNAG+Q+ + +  T DG E TF VN L +  L
Sbjct  64   SLRSVSEAADEVVELVHPGRLPPIGALVCNAGVQLTNALTETVDGFEATFAVNVLANHVL  123

Query  120  VTGILDWLARPARIVVVSSGTH--DPSKHTGM-PDPRY----TCAADLAHPPTDQNTPAE  172
            +  +   L   AR+VV  S TH  D   + GM P P +    T A   A P  D +    
Sbjct  124  LRRLQGHLPPSARVVVTVSDTHFGDLRHNLGMVPGPLWHPVETLARVAAFP--DPSGSTA  181

Query  173  GRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLL  232
            GR  Y+TSKL  +   +E  RRL     G+ + +F+PG +PG+ LARD   I R A R +
Sbjct  182  GRAAYSTSKLAAIYLVHEYARRL---PTGLTITSFNPGFVPGTDLARDADAISRFAMRRV  238

Query  233  SPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWE  292
             P+L + P   S  ++G  LA  AV    +  TG Y    +   SS  SYDR +  + WE
Sbjct  239  MPLLTLTPLATSPSLAGRFLAD-AVLGTVSAPTGAYIDRDRVAASSPASYDRQREREAWE  297

Query  293  TSERLLAQ  300
              E L A+
Sbjct  298  AVEALTAR  305


>gi|302543101|ref|ZP_07295443.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces 
hygroscopicus ATCC 53653]
 gi|302460719|gb|EFL23812.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces 
himastatinicus ATCC 53653]
Length=338

 Score =  145 bits (367),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 109/303 (36%), Positives = 152/303 (51%), Gaps = 19/303 (6%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNR-CSVLEVDLA  63
            T V+TGA+ G+G   A  +LRR    H+++  R+     A+  +L    R  S +  DL 
Sbjct  40   TLVMTGATRGIGRVAAEQILRRSPDTHLLVVARE-----ASGVQLATGGRTVSYVPADLG  94

Query  64   SVRSVRSFVETVR----TTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFAL  119
            S+RSVRS    +R    +  LPP+RA V NAG+Q  + +    DG E TF VN L H  L
Sbjct  95   SLRSVRSAATEIRARLDSGALPPLRAYVGNAGVQHTNALTEGPDGFESTFTVNVLAHHLL  154

Query  120  VTGILDWLARPARIVVVSSGTH--DPSKHTGM-PDPRYTCAADLAHPPT--DQNTPAEGR  174
            +  +       ARIV+ +S TH  D   + GM P P +     LA         T A GR
Sbjct  155  IRLLQGHFTAAARIVITASDTHFGDLRHNLGMVPGPAWKSPDILARTGAFPRPGTTAAGR  214

Query  175  RRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSP  234
              Y TSKL  +   +E  RRL  G   V   A++PG +PG+GLAR   P+ R A R + P
Sbjct  215  TAYATSKLATIYLVHEYARRLPTGIDAV---AYNPGFVPGTGLARHADPLSRFAMRRILP  271

Query  235  MLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETS  294
             + + PF  +   +G +LA + +    A  TG Y    +  RSS ESYD  +  +LW+  
Sbjct  272  AMTLTPFATTRGAAGRYLADVVLGTTRA-PTGSYVDRGREARSSEESYDPRREGELWDAV  330

Query  295  ERL  297
            ER 
Sbjct  331  ERF  333


>gi|255078496|ref|XP_002502828.1| light-dependent protochlorophyllide oxido-reductase [Micromonas 
sp. RCC299]
 gi|226518094|gb|ACO64086.1| light-dependent protochlorophyllide oxido-reductase [Micromonas 
sp. RCC299]
Length=409

 Score =  145 bits (367),  Expect = 5e-33, Method: Compositional matrix adjust.
 Identities = 116/326 (36%), Positives = 153/326 (47%), Gaps = 43/326 (13%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG------EPNRCSVLEV  60
            VITG++SG+G   A+ L +    W VVLA R  A+   A   +       +PN       
Sbjct  90   VITGSNSGIGFDAAKKLAK-SGDWCVVLACRTVAKAEQAKASMRSEFPSIDPNDVQCYAC  148

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSG---IAFTDDGVEMTFGVNHLGHF  117
            DL  + S+R F + V  T   P+ AL  NAGL+  SG   +  T DG E T GVNHLGHF
Sbjct  149  DLGDMASIRRFAKDV--TAEGPVDALCLNAGLEY-SGDPTVYRTKDGFEETIGVNHLGHF  205

Query  118  ALVTGIL------DWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNT--  169
             L   +L      + LA P RIVV +S  HDP+   G      T   DLA    D     
Sbjct  206  LLANLLLPALESSEKLAHP-RIVVTASEVHDPASAGGSVGKGATLG-DLAGLERDGKNFE  263

Query  170  -----PAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPI  224
                 P +  + Y  SKLCN+LF+YEL+RRL      V VNAF PGL+  +GL R   P+
Sbjct  264  MVSGEPYDADKAYKDSKLCNMLFSYELERRLQASGSKVTVNAFGPGLITRTGLFRHQQPL  323

Query  225  LRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKA----------  274
               A+ L++    V     S    G  L  +  D    GV G Y++   +          
Sbjct  324  FVKAFDLITNTFNV---AESVDGGGNTLLYMLTDESLEGVGGAYYSNTISPGSSPTGHAF  380

Query  275  --IRSSAESYDRAKALDLWETSERLL  298
                SS ES D  +A +LW  SE+L+
Sbjct  381  IVQESSEESKDATEARNLWRLSEKLV  406


>gi|46019982|emb|CAD99008.1| NADPH-protochlorophyllide oxidoreductase [Zea mays]
Length=371

 Score =  145 bits (367),  Expect = 6e-33, Method: Compositional matrix adjust.
 Identities = 113/321 (36%), Positives = 160/321 (50%), Gaps = 31/321 (9%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLE  59
            +  GTAVITGASSGLGL  A+AL      WHV++A RD  +   A +  G + +  +V+ 
Sbjct  56   LRKGTAVITGASSGLGLATAKALAE-TGKWHVIMACRDFLKASRAAKAAGMDKDSFTVVH  114

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHF  117
            +DLAS+ SVR FV  VR   +P I  +VCNA +        ++T DG EM+ GVNHLGHF
Sbjct  115  LDLASLDSVRQFVRNVRQLKMP-IDVVVCNAAVYQPTAKEPSYTADGFEMSVGVNHLGHF  173

Query  118  ALVTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPA--  171
             L   +L  L        R+++V S T + +   G   P+     DL       N     
Sbjct  174  LLARELLSDLQSSDYPSKRLIIVGSITGNTNTLAGNVPPKANL-GDLRGLAGGLNGVGSS  232

Query  172  --------EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPP  223
                    +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P
Sbjct  233  VMIDGGEFDGAKAYKDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIP  291

Query  224  ILRLAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----  277
            + RL   L  P  + +   + S   +G+ LA +  DP     +G Y++  K   S     
Sbjct  292  LFRL---LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLTK-SGVYWSWNKNSASFENQL  347

Query  278  SAESYDRAKALDLWETSERLL  298
            S E+ D  KA  LWE SE+L+
Sbjct  348  SEEASDADKAKKLWEISEKLV  368


>gi|194697158|gb|ACF82663.1| unknown [Zea mays]
Length=365

 Score =  145 bits (366),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 113/321 (36%), Positives = 160/321 (50%), Gaps = 31/321 (9%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLE  59
            +  GTAVITGASSGLGL  A+AL      WHV++A RD  +   A +  G + +  +V+ 
Sbjct  50   LRKGTAVITGASSGLGLATAKALAE-TGKWHVIMACRDFLKASRAAKAAGMDKDSFTVVH  108

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHF  117
            +DLAS+ SVR FV  VR   +P I  +VCNA +        ++T DG EM+ GVNHLGHF
Sbjct  109  LDLASLDSVRQFVRNVRQLEMP-IDVVVCNAAVYQPTAKEPSYTADGFEMSVGVNHLGHF  167

Query  118  ALVTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPA--  171
             L   +L  L        R+++V S T + +   G   P+     DL       N     
Sbjct  168  LLARELLSDLQSSDYPSKRLIIVGSITGNTNTLAGNVPPKANL-GDLRGLAGGLNGVGSS  226

Query  172  --------EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPP  223
                    +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P
Sbjct  227  VMIDGGEFDGAKAYKDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIP  285

Query  224  ILRLAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----  277
            + RL   L  P  + +   + S   +G+ LA +  DP     +G Y++  K   S     
Sbjct  286  LFRL---LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLTK-SGVYWSWNKNSASFENQL  341

Query  278  SAESYDRAKALDLWETSERLL  298
            S E+ D  KA  LWE SE+L+
Sbjct  342  SEEASDADKAKKLWEISEKLV  362


>gi|293337123|ref|NP_001167680.1| protochlorophyllide reductase B [Zea mays]
 gi|195626834|gb|ACG35247.1| protochlorophyllide reductase B [Zea mays]
 gi|238011622|gb|ACR36846.1| unknown [Zea mays]
Length=396

 Score =  145 bits (366),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 113/321 (36%), Positives = 160/321 (50%), Gaps = 31/321 (9%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLE  59
            +  GTAVITGASSGLGL  A+AL      WHV++A RD  +   A +  G + +  +V+ 
Sbjct  81   LRKGTAVITGASSGLGLATAKALAET-GKWHVIMACRDFLKASRAAKAAGMDKDSFTVVH  139

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHF  117
            +DLAS+ SVR FV  VR   +P I  +VCNA +        ++T DG EM+ GVNHLGHF
Sbjct  140  LDLASLDSVRQFVRNVRQLEMP-IDVVVCNAAVYQPTAKEPSYTADGFEMSVGVNHLGHF  198

Query  118  ALVTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPA--  171
             L   +L  L        R+++V S T + +   G   P+     DL       N     
Sbjct  199  LLARELLSDLQSSDYPSKRLIIVGSITGNTNTLAGNVPPKANL-GDLRGLAGGLNGVGSS  257

Query  172  --------EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPP  223
                    +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P
Sbjct  258  VMIDGGEFDGAKAYKDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIP  316

Query  224  ILRLAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----  277
            + RL   L  P  + +   + S   +G+ LA +  DP     +G Y++  K   S     
Sbjct  317  LFRL---LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLTK-SGVYWSWNKNSASFENQL  372

Query  278  SAESYDRAKALDLWETSERLL  298
            S E+ D  KA  LWE SE+L+
Sbjct  373  SEEASDADKAKKLWEISEKLV  393


>gi|15218860|ref|NP_171860.1| protochlorophyllide reductase C [Arabidopsis thaliana]
 gi|10720234|sp|O48741.1|PORC_ARATH RecName: Full=Protochlorophyllide reductase C, chloroplastic; 
Short=PCR C; AltName: Full=NADPH-protochlorophyllide oxidoreductase 
C; Short=POR C; Flags: Precursor
 gi|9280649|gb|AAF86518.1|AC002560_11 F21B7.24 [Arabidopsis thaliana]
 6 more sequence titles
 Length=401

 Score =  145 bits (365),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 113/316 (36%), Positives = 161/316 (51%), Gaps = 28/316 (8%)

Query  4    GTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLEVDL  62
            GTAVITGASSGLGL  A+AL      WHV++A R+  +   A   +G      +V+ +DL
Sbjct  90   GTAVITGASSGLGLATAKALA-DTGKWHVIMACRNFLKAEKAARSVGMSKEDYTVMHLDL  148

Query  63   ASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHFALV  120
            AS+ SV+ FVE  R T   P+  LVCNA +        +FT +G E++ G NHLGHF L 
Sbjct  149  ASLESVKQFVENFRRTE-QPLDVLVCNAAVYQPTAKEPSFTAEGFEISVGTNHLGHFLLS  207

Query  121  TGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAA--DLAHPPTDQNTPA---  171
              +LD L +      R+++V S T + +   G   P+        LA     QN+     
Sbjct  208  RLLLDDLKKSDYPSKRMIIVGSITGNTNTLAGNVPPKANLGDLRGLASGLNGQNSSMIDG  267

Query  172  ---EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLA  228
               +G + Y  SK+CN+L   EL RR  H E GV   +  PG +  +GL R++ P+ RL 
Sbjct  268  GEFDGAKAYKDSKVCNMLTMQELHRRY-HEETGVTFASLYPGCIATTGLFREHIPLFRL-  325

Query  229  YRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----SAESY  282
              L  P  + +   + S   +G+ LA +  DP   G +G Y++      S     S E+ 
Sbjct  326  --LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSL-GKSGVYWSWNNNSSSFENQLSKEAS  382

Query  283  DRAKALDLWETSERLL  298
            D  KA  LWE SE+L+
Sbjct  383  DAEKAKKLWEVSEKLV  398


>gi|79316418|ref|NP_001030948.1| protochlorophyllide reductase C [Arabidopsis thaliana]
 gi|332189471|gb|AEE27592.1| protochlorophyllide reductase C [Arabidopsis thaliana]
Length=399

 Score =  144 bits (364),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 113/316 (36%), Positives = 161/316 (51%), Gaps = 28/316 (8%)

Query  4    GTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLEVDL  62
            GTAVITGASSGLGL  A+AL      WHV++A R+  +   A   +G      +V+ +DL
Sbjct  88   GTAVITGASSGLGLATAKALA-DTGKWHVIMACRNFLKAEKAARSVGMSKEDYTVMHLDL  146

Query  63   ASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHFALV  120
            AS+ SV+ FVE  R T   P+  LVCNA +        +FT +G E++ G NHLGHF L 
Sbjct  147  ASLESVKQFVENFRRTE-QPLDVLVCNAAVYQPTAKEPSFTAEGFEISVGTNHLGHFLLS  205

Query  121  TGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAA--DLAHPPTDQNTPA---  171
              +LD L +      R+++V S T + +   G   P+        LA     QN+     
Sbjct  206  RLLLDDLKKSDYPSKRMIIVGSITGNTNTLAGNVPPKANLGDLRGLASGLNGQNSSMIDG  265

Query  172  ---EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLA  228
               +G + Y  SK+CN+L   EL RR  H E GV   +  PG +  +GL R++ P+ RL 
Sbjct  266  GEFDGAKAYKDSKVCNMLTMQELHRRY-HEETGVTFASLYPGCIATTGLFREHIPLFRL-  323

Query  229  YRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----SAESY  282
              L  P  + +   + S   +G+ LA +  DP   G +G Y++      S     S E+ 
Sbjct  324  --LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSL-GKSGVYWSWNNNSSSFENQLSKEAS  380

Query  283  DRAKALDLWETSERLL  298
            D  KA  LWE SE+L+
Sbjct  381  DAEKAKKLWEVSEKLV  396


>gi|154313450|ref|XP_001556051.1| hypothetical protein BC1G_05422 [Botryotinia fuckeliana B05.10]
 gi|150849491|gb|EDN24684.1| hypothetical protein BC1G_05422 [Botryotinia fuckeliana B05.10]
Length=220

 Score =  144 bits (364),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 88/209 (43%), Positives = 118/209 (57%), Gaps = 9/209 (4%)

Query  100  FTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAAD  159
             T +G+E TF + H+GH  L   +   LA  +R+V  SSGTHDP++ TGM  P Y  A D
Sbjct  1    MTPEGLEATFAIAHVGHALLFFLLCPHLAPDSRVVFTSSGTHDPTQKTGMSGPEYNTAED  60

Query  160  LAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDH--GEQGVMVNAFDPGLMPGSGL  217
            L  PP +      GR+RYTT+KLCNVLF Y + R+L     E+ + V A DPGLMPG+GL
Sbjct  61   LDRPP-ESMIEIPGRKRYTTAKLCNVLFAYAISRKLTEPAPERHITVTAMDPGLMPGTGL  119

Query  218  ARDYPPILRLAYRLLSP----MLRVL--PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAG  271
            AR+     +  +  + P    +LR+L  P  ++   SG  LA LA      G TG+YF  
Sbjct  120  AREANKFEQWLWNSVLPHMIWLLRLLATPNTNTPAESGTALARLATAADVKGTTGKYFEE  179

Query  272  AKAIRSSAESYDRAKALDLWETSERLLAQ  300
               I+SS +SYD  K  DLW  +   LA+
Sbjct  180  LSEIKSSKDSYDEGKQEDLWNWTVSYLAK  208


>gi|10720236|sp|Q42850.1|PORB_HORVU RecName: Full=Protochlorophyllide reductase B, chloroplastic; 
Short=PCR B; AltName: Full=NADPH-protochlorophyllide oxidoreductase 
B; Short=POR B; Flags: Precursor
 gi|683476|emb|CAA59228.1| NADPH dehydrogenase [Hordeum vulgare]
 gi|326488707|dbj|BAJ97965.1| predicted protein [Hordeum vulgare subsp. vulgare]
 gi|326493324|dbj|BAJ85123.1| predicted protein [Hordeum vulgare subsp. vulgare]
 gi|326494290|dbj|BAJ90414.1| predicted protein [Hordeum vulgare subsp. vulgare]
Length=395

 Score =  144 bits (364),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 111/318 (35%), Positives = 159/318 (50%), Gaps = 29/318 (9%)

Query  3    TGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPN-RCSVLEVD  61
            TG A+ITGASSGLGL  A+AL      WHV++A RD  +   A    G P    +++ +D
Sbjct  82   TGNAIITGASSGLGLATAKALAE-SGKWHVIMACRDYLKTARAARAAGMPKGSYTIVHLD  140

Query  62   LASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHFAL  119
            LAS+ SVR FV+ VR   +P I  +VCNA +        +FT DG EM+ GVNHLGHF L
Sbjct  141  LASLDSVRQFVKNVRQLDMP-IDVVVCNAAVYQPTAKEPSFTADGFEMSVGVNHLGHFLL  199

Query  120  VTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYT------CAADL---AHPPTD  166
               +L+ L        R+++V S T + +   G   P+         AA L         
Sbjct  200  ARELLEDLKASDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAAGLNGVGSAAMI  259

Query  167  QNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILR  226
                 +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P+ R
Sbjct  260  DGAEFDGAKAYKDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIPLFR  318

Query  227  LAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----SAE  280
            L   L  P  + +   + S   +G+ LA +  +P     +G Y++  K   S     S E
Sbjct  319  L---LFPPFQKYITKGYVSEEEAGKRLAQVVSEPSLTK-SGVYWSWNKNSASFENQLSEE  374

Query  281  SYDRAKALDLWETSERLL  298
            + D  KA  +WE SE+L+
Sbjct  375  ASDTEKARKVWELSEKLV  392


>gi|75248671|sp|Q8W3D9.1|PORB_ORYSJ RecName: Full=Protochlorophyllide reductase B, chloroplastic; 
Short=PCR B; AltName: Full=NADPH-protochlorophyllide oxidoreductase 
B; Short=POR B; Flags: Precursor
 gi|18071421|gb|AAL58280.1|AC068923_22 putative dehydrogenase [Oryza sativa Japonica Group]
 gi|31432862|gb|AAP54438.1| Protochlorophyllide reductase B, chloroplast precursor, putative, 
expressed [Oryza sativa Japonica Group]
Length=402

 Score =  144 bits (364),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 111/319 (35%), Positives = 161/319 (51%), Gaps = 27/319 (8%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLE  59
            +  GTAVITGASSGLGL  A+AL      WHVV+  RD  +   A +  G E    +++ 
Sbjct  83   LRKGTAVITGASSGLGLATAKALAE-TGRWHVVMGCRDFLKASRAAKAAGMEKGSYTIVH  141

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHF  117
            +DLAS+ SVR FV  VR   +P +  +VCNA +        +FT DG EM+ GVNHLGHF
Sbjct  142  LDLASLDSVRQFVANVRRLEMP-VDVVVCNAAVYQPTAKQPSFTADGFEMSVGVNHLGHF  200

Query  118  ALVTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAA--DLAHPPTDQNTPA  171
             L   +L  L        R+++V S T + +   G   P+        LA      ++ A
Sbjct  201  LLARELLADLTSSDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLASGLDGVSSSA  260

Query  172  -------EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPI  224
                   +G + Y  SK+CN+L   E  RR  HGE GV   +  PG +  +GL R++ P+
Sbjct  261  MIDGGEFDGAKAYKDSKVCNMLTMQEFHRRY-HGETGVTFASLYPGCIATTGLFREHVPL  319

Query  225  LRLAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRF--AGVTGQYFAGAKAIRS--SA  279
             RL   L  P  + +   + S   +G+ LA +  DP    +GV   +   + +  +  S 
Sbjct  320  FRL---LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLTKSGVYWSWNNNSASFENQLSE  376

Query  280  ESYDRAKALDLWETSERLL  298
            E+ D  KA  +WE SE+L+
Sbjct  377  EASDPEKAKKVWELSEKLV  395


>gi|284814268|gb|ADB97492.1| NADPH-protochlorophyllide oxidoreductase B [Hordeum vulgare]
Length=395

 Score =  144 bits (362),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 111/318 (35%), Positives = 159/318 (50%), Gaps = 29/318 (9%)

Query  3    TGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPN-RCSVLEVD  61
            TG A+ITGASSGLGL  A+AL      WHV++A RD  +   A    G P    +++ +D
Sbjct  82   TGNAIITGASSGLGLATAKALAE-SGKWHVIMACRDYLKTARAARAAGMPKGSYTIVHLD  140

Query  62   LASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHFAL  119
            LAS+ SVR FV+ VR   +P I  +VCNA +        +FT DG EM+ GVNHLGHF L
Sbjct  141  LASLDSVRQFVKNVRQLDMP-IDVVVCNAAVYQPTAKEPSFTADGFEMSVGVNHLGHFLL  199

Query  120  VTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYT------CAADL---AHPPTD  166
               +L+ L        R+++V S T + +   G   P+         AA L         
Sbjct  200  ARELLEDLKASDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAAGLNGVGSAAMI  259

Query  167  QNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILR  226
                 +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P+ R
Sbjct  260  DGAEFDGAKAYRDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIPLFR  318

Query  227  LAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----SAE  280
            L   L  P  + +   + S   +G+ LA +  +P     +G Y++  K   S     S E
Sbjct  319  L---LFPPFQKYITKGYVSEEEAGKRLAQVVSEPSLTK-SGVYWSWNKNSASFENQLSEE  374

Query  281  SYDRAKALDLWETSERLL  298
            + D  KA  +WE SE+L+
Sbjct  375  ASDTEKARKVWELSEKLV  392


>gi|226500452|ref|NP_001149903.1| protochlorophyllide reductase B [Zea mays]
 gi|194701902|gb|ACF85035.1| unknown [Zea mays]
 gi|195635367|gb|ACG37152.1| protochlorophyllide reductase B [Zea mays]
Length=396

 Score =  144 bits (362),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 110/321 (35%), Positives = 161/321 (51%), Gaps = 31/321 (9%)

Query  1    MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLE  59
            +  GTA+ITGASSGLGL  A+AL      WHV++A RD  +   A +  G + +  +V+ 
Sbjct  81   LRKGTAIITGASSGLGLATAKAL-AETGKWHVIMACRDFLKASRAAKAAGMDKDSFTVVH  139

Query  60   VDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHF  117
            +DLAS+ SVR FV+ VR   +P +  +VCNA +        ++T DG EM+ GVNHLGHF
Sbjct  140  LDLASLDSVRQFVKNVRQLEMP-VDVVVCNAAVYQPTAKEPSYTADGFEMSVGVNHLGHF  198

Query  118  ALVTGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPA--  171
             L   +L  L        R+++V S T + +   G   P+     DL       N     
Sbjct  199  LLARELLSDLQSSDYPSKRLIIVGSITGNTNTLAGNVPPKANL-GDLRGLAGGLNGIGGS  257

Query  172  --------EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPP  223
                    +G + Y  SK+CN+L   E  RR  H E GV   +  PG +  +GL R++ P
Sbjct  258  AMIDGGEFDGAKAYKDSKVCNMLTMQEFHRRY-HEETGVTFASLYPGCIATTGLFREHIP  316

Query  224  ILRLAYRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----  277
            + RL   L  P  + +   + S   +G+ L+ +  DP     +G Y++  K   S     
Sbjct  317  LFRL---LFPPFQKYITKGYVSEEEAGKRLSQVVSDPSLTK-SGVYWSWNKNSASFENQL  372

Query  278  SAESYDRAKALDLWETSERLL  298
            S E+ D  KA  LWE SE+L+
Sbjct  373  SEEASDADKAKKLWEISEKLV  393


>gi|297843168|ref|XP_002889465.1| por C [Arabidopsis lyrata subsp. lyrata]
 gi|297335307|gb|EFH65724.1| por C [Arabidopsis lyrata subsp. lyrata]
Length=401

 Score =  143 bits (361),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 112/316 (36%), Positives = 161/316 (51%), Gaps = 28/316 (8%)

Query  4    GTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELG-EPNRCSVLEVDL  62
            GTAVITGASSGLGL  A+AL      WHV++A R+  +   A   +G      +V+ +DL
Sbjct  90   GTAVITGASSGLGLATAKALA-DTGKWHVIMACRNFLKAEKAARSVGMSKEDYTVMHLDL  148

Query  63   ASVRSVRSFVETVRTTPLPPIRALVCNAGLQ--VVSGIAFTDDGVEMTFGVNHLGHFALV  120
            AS+ SV+ FV+  R T   P+  LVCNA +        +FT +G E++ G NHLGHF L 
Sbjct  149  ASLESVKQFVDNFRRTE-QPLDVLVCNAAVYQPTAKEPSFTAEGFELSVGTNHLGHFLLS  207

Query  121  TGILDWLAR----PARIVVVSSGTHDPSKHTGMPDPRYTCAA--DLAHPPTDQNTPA---  171
              +LD L +      R+++V S T + +   G   P+        LA     QN+     
Sbjct  208  RLLLDDLKKSDYPSKRMIIVGSITGNTNTLAGNVPPKANLGDLRGLASGLNGQNSSMIDG  267

Query  172  ---EGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLA  228
               +G + Y  SK+CN+L   EL RR  H E GV   +  PG +  +GL R++ P+ RL 
Sbjct  268  GEFDGAKAYKDSKVCNMLTMQELHRRY-HEETGVTFASLYPGCIATTGLFREHIPLFRL-  325

Query  229  YRLLSPMLRVLPFVH-STRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRS-----SAESY  282
              L  P  + +   + S   +G+ LA +  DP   G +G Y++      S     S E+ 
Sbjct  326  --LFPPFQKYITKGYVSEEEAGKRLAQVVSDPSL-GKSGVYWSWNNNSSSFENQLSKEAS  382

Query  283  DRAKALDLWETSERLL  298
            D  KA  LWE SE+L+
Sbjct  383  DAEKAKKLWEVSEKLV  398


>gi|31980962|ref|NP_062519.2| WW domain-containing oxidoreductase [Mus musculus]
 gi|81879603|sp|Q91WL8.1|WWOX_MOUSE RecName: Full=WW domain-containing oxidoreductase
 gi|15928476|gb|AAH14716.1| WW domain-containing oxidoreductase [Mus musculus]
 gi|26347353|dbj|BAC37325.1| unnamed protein product [Mus musculus]
Length=414

 Score =  142 bits (358),  Expect = 7e-32, Method: Compositional matrix adjust.
 Identities = 109/302 (37%), Positives = 148/302 (50%), Gaps = 25/302 (8%)

Query  3    TGTAV-ITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE---PNRCSVL  58
            TG  V +TGA+SG+G + A++     A  HV+LA R+ +R   A+  + E     +   +
Sbjct  123  TGKVVLVTGANSGIGFETAKSFALHGA--HVILACRNLSRASEAVSRILEEWHKAKVEAM  180

Query  59   EVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFA  118
             +DLA +RSV+ F E  +   +  +  LVCNAG   +     T DG+E TF VNHLGHF 
Sbjct  181  TLDLAVLRSVQHFAEAFKAKNVS-LHVLVCNAGTFALP-WGLTKDGLETTFQVNHLGHFY  238

Query  119  LVTGILDWLAR--PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRR  176
            LV  + D L R  PAR++VVSS +H   + T + D           PP    +       
Sbjct  239  LVQLLQDVLCRSSPARVIVVSSESH---RFTDINDSSGKLDLSRLSPP---RSDYWAMLA  292

Query  177  YTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPML  236
            Y  SKLCN+LF+ EL RRL    +GV  NA  PG M  S + R+        Y+LL  + 
Sbjct  293  YNRSKLCNILFSNELHRRL--SPRGVTSNAVHPGNMMYSAIHRN-----SWVYKLLFTLA  345

Query  237  RVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSER  296
            R  PF  S +         AV P   G+ G YF        S E+     A  LWE SER
Sbjct  346  R--PFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWELSER  403

Query  297  LL  298
            L+
Sbjct  404  LI  405


>gi|332846578|ref|XP_001144696.2| PREDICTED: WW domain-containing oxidoreductase isoform 2 [Pan 
troglodytes]
Length=414

 Score =  142 bits (357),  Expect = 9e-32, Method: Compositional matrix adjust.
 Identities = 111/300 (37%), Positives = 151/300 (51%), Gaps = 26/300 (8%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEE-LGEPNRCSV--LEVDLA  63
            V+TGA+SG+G + A++     A  HV+LA R+ AR   A+   LGE ++  V  + +DLA
Sbjct  128  VVTGANSGIGFETAKSFALHGA--HVILACRNMARASEAVSRILGEWHKAKVEAMTLDLA  185

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGI  123
             +RSV+ F E  +   +P +  LVCNA    +   + T DG+E TF VNHLGHF LV  +
Sbjct  186  LLRSVQHFAEAFKAKNVP-LHVLVCNAATFALP-WSLTKDGLETTFQVNHLGHFYLVQLL  243

Query  124  LDWLAR--PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAH-PPTDQNTPAEGRRRYTTS  180
             D L R  PAR++VVSS +H   + T + D       D +   PT  +  A     Y  S
Sbjct  244  QDVLCRSAPARVIVVSSESH---RFTDINDS--LGKLDFSRLSPTKNDYWA--MLAYNRS  296

Query  181  KLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLP  240
            KLCN+LF+ EL RRL    +GV  NA  PG M  S + R +       Y LL  + R  P
Sbjct  297  KLCNILFSNELHRRL--SPRGVTSNAVHPGNMMYSNIHRSW-----WVYTLLFTLAR--P  347

Query  241  FVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQ  300
            F  S +         A  P   G+ G YF        S E+     A  LW  SERL+ +
Sbjct  348  FTKSMQQGAATTVYCAAAPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWVLSERLIQE  407


>gi|289157495|gb|ADC84385.1| WW domain-containing oxidoreductase [Bos taurus]
Length=414

 Score =  142 bits (357),  Expect = 9e-32, Method: Compositional matrix adjust.
 Identities = 115/302 (39%), Positives = 152/302 (51%), Gaps = 28/302 (9%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEE-LGEPNRCSV--LEVDLA  63
            V+TGA+SG+G + A++     A  HV+LA R+  R   A+   LGE ++  V  + +DLA
Sbjct  128  VVTGANSGIGFETAKSFALHGA--HVILACRNMTRANEAVSRILGEWHKAKVEAMTLDLA  185

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFT--DDGVEMTFGVNHLGHFALVT  121
             +RSV+ F +  +   +  +  LVCNA    V G+ +T   DG+E TF VNHLGHF LV 
Sbjct  186  LLRSVQHFAQAFKAKNVS-LHVLVCNAA---VFGLPWTLTKDGLETTFQVNHLGHFYLVQ  241

Query  122  GILDWLAR--PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTT  179
             + D L R  PARIVVVSS +H   + T + D   +   D +     +N        Y  
Sbjct  242  LLQDVLCRSAPARIVVVSSESH---RFTDINDS--SGKLDFSRLSPSKN-DYWAMLAYNR  295

Query  180  SKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVL  239
            SKLCN+LF+ EL RRL    +GV  NA  PG M  S L R +       Y LL  + R  
Sbjct  296  SKLCNILFSNELHRRL--SPRGVTSNAVHPGNMMYSALHRGW-----WVYTLLFTLAR--  346

Query  240  PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLA  299
            PF  S +         AV P   G+ G YF        SAE+     A  LW  SERLL 
Sbjct  347  PFTKSMQQGAATTVYCAVAPELEGLGGMYFNSCCRCLPSAEAQSEDSARALWALSERLLQ  406

Query  300  QV  301
             V
Sbjct  407  GV  408


>gi|221130525|ref|XP_002161049.1| PREDICTED: similar to WW domain-containing oxidoreductase [Hydra 
magnipapillata]
Length=412

 Score =  141 bits (356),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 107/302 (36%), Positives = 152/302 (51%), Gaps = 33/302 (10%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAA----MEELGEPNRCSVLEV  60
            TA+ITGA+SG+G + A AL       HV+LA R   +G  A    +++   P +  V+E 
Sbjct  122  TALITGANSGIGFETALALSLHGC--HVILACRTKIKGEQAASLILKKQKIPIKVDVVEC  179

Query  61   DLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFT--DDGVEMTFGVNHLGHFA  118
            DLAS+ SV+   ET+       I+ L+CNAG   V G+ ++   DG+E TF +NHLGHF 
Sbjct  180  DLASLDSVKRCAETILLKKWA-IKILICNAG---VMGLPYSLSSDGIESTFAINHLGHFY  235

Query  119  LVTGILDWL--ARPARIVVVSSGTHD-PSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRR  175
            LV  + D L  + PAR+++VSS +H  PS +    + R     D+    +D  +      
Sbjct  236  LVNLLKDVLLSSAPARVIIVSSESHRFPSLYGDTFEIR-----DVPMKKSDYISMVA---  287

Query  176  RYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPM  235
             Y  SKLCN+LF +EL+RRL+    GV  NA  PG +  + + R         Y+LL  +
Sbjct  288  -YNQSKLCNLLFAFELNRRLE--SFGVTCNAVTPGCLISTSIQRH-----SYFYKLLFLL  339

Query  236  LRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSE  295
             R  PF  S       L   A      GV G YF        S  S +   A +LW+ SE
Sbjct  340  AR--PFAKSQCQGASTLVYCAASLEMEGVGGFYFNNCAGCAPSQLSLNEQLAKELWDFSE  397

Query  296  RL  297
            +L
Sbjct  398  KL  399


>gi|284042392|ref|YP_003392732.1| Protochlorophyllide reductase [Conexibacter woesei DSM 14684]
 gi|283946613|gb|ADB49357.1| Protochlorophyllide reductase [Conexibacter woesei DSM 14684]
Length=301

 Score =  141 bits (355),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 123/304 (41%), Positives = 158/304 (52%), Gaps = 12/304 (3%)

Query  5    TAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEVDLAS  64
            T VITGA+SGLG  CA  L      W VV+A RD ARG AA   LG       L +DLA 
Sbjct  4    TVVITGATSGLGRACAGELAGLP-EWTVVVAARDRARGAAAARALGGGASHVTLPLDLAD  62

Query  65   VRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGIL  124
            + SVR+F   +    LPP+ A+V NAG+Q       T  G E TF VNHL HF L+  +L
Sbjct  63   LDSVRAFPAALDAAGLPPLHAVVANAGIQHRDRRHTTAQGYEATFAVNHLAHFLLLRLLL  122

Query  125  DWLARPARIVVVSSGTHDPS--KHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKL  182
              LA   R+ +V+SG H P   ++ G P PR+     LA P      P  G+  Y  SKL
Sbjct  123  GQLADGGRVAIVASGVHKPQRLRNFGFPPPRWDEPERLAEP-----GPGSGQIAYANSKL  177

Query  183  CNVLFTYELDRRLD--HGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPML-RVL  239
             NV+   EL RR+D      G+ V+A DPGLMP + L R YP  +R  Y  L+P+L R+ 
Sbjct  178  ANVMTALELARRIDTLRPGAGIAVHALDPGLMPETALTRGYPAPVRRLYPRLAPLLARLA  237

Query  240  PFVHSTRVSGEHLAALAVDPRFAG-VTGQYFAGAKAIRSSAESYDRAKALDLWETSERLL  298
            P   S   SG  LA +  DP +A    G+Y    +    S  + D   A  LW  SERL+
Sbjct  238  PGATSAAGSGGQLARMVADPAYAAPPNGRYVELTRDGEPSPLARDPELAARLWSESERLV  297

Query  299  AQVT  302
              ++
Sbjct  298  GGIS  301


>gi|118151256|ref|NP_001071560.1| WW domain-containing oxidoreductase [Bos taurus]
 gi|112362377|gb|AAI19824.1| WW domain containing oxidoreductase [Bos taurus]
 gi|289157497|gb|ADC84386.1| WW domain-containing oxidoreductase [Bos taurus]
 gi|296478198|gb|DAA20313.1| WW domain-containing oxidoreductase [Bos taurus]
Length=414

 Score =  141 bits (355),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 114/302 (38%), Positives = 152/302 (51%), Gaps = 28/302 (9%)

Query  7    VITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEE-LGEPNRCSV--LEVDLA  63
            V+TGA+SG+G + A++     A  HV+LA R+  R   A+   LGE ++  V  + +DLA
Sbjct  128  VVTGANSGIGFETAKSFALHGA--HVILACRNMTRANEAVSRILGEWHKAKVEAMTLDLA  185

Query  64   SVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFT--DDGVEMTFGVNHLGHFALVT  121
             +RSV+ F +  +   +  +  LVCNA    V G+ +T   DG+E TF VNHLGHF LV 
Sbjct  186  LLRSVQHFAQAFKAKNVS-LHVLVCNAA---VFGLPWTLTKDGLETTFQVNHLGHFYLVQ  241

Query  122  GILDWLAR--PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTT  179
             + D L R  PAR+VVVSS +H   + T + D   +   D +     +N        Y  
Sbjct  242  LLQDVLCRSAPARVVVVSSESH---RFTDINDS--SGKLDFSRLSPSKN-DYWAMLAYNR  295

Query  180  SKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVL  239
            SKLCN+LF+ EL RRL    +GV  NA  PG M  S L R +       Y LL  + R  
Sbjct  296  SKLCNILFSNELHRRL--SPRGVTSNAVHPGNMMYSALHRGW-----WVYTLLFTLAR--  346

Query  240  PFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLA  299
            PF  S +         AV P   G+ G YF        SAE+     A  LW  SERLL 
Sbjct  347  PFTKSMQQGAATTVYCAVAPELEGLGGMYFNSCCRCLPSAEAQSEDSARALWALSERLLQ  406

Query  300  QV  301
             V
Sbjct  407  GV  408


>gi|334313155|ref|XP_001368394.2| PREDICTED: WW domain-containing oxidoreductase [Monodelphis domestica]
Length=414

 Score =  141 bits (355),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 109/304 (36%), Positives = 151/304 (50%), Gaps = 25/304 (8%)

Query  3    TGTAVI-TGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGE---PNRCSVL  58
            TG  VI TGA+SG+G + A++     A   V+LA R+ AR   A+  + E     +   +
Sbjct  123  TGKVVIVTGANSGIGFETAKSFALHGA--QVILACRNMARANEAVSRILEEWHKAKVEAM  180

Query  59   EVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFA  118
             +DLAS+RSV++F E  ++  +  +  LVCNA +  +   + T D +E TF VNHLGHF 
Sbjct  181  TLDLASLRSVQNFAEAFKSKNIS-LHVLVCNAAVFALPW-SLTKDHLETTFQVNHLGHFY  238

Query  119  LVTGILDWLAR--PARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRR  176
            LV  + + L R  PARIVVVSS +H   + T + D        L  P  +          
Sbjct  239  LVQLLQEVLCRSAPARIVVVSSESH---RFTDINDSSGKLDLSLLSPSKEDFWSMLA---  292

Query  177  YTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPML  236
            Y  SKLCN+LF+ EL  RL     GV  NA  PG M  S + +++       Y LL  + 
Sbjct  293  YNRSKLCNILFSNELHCRL--SPHGVTSNAVHPGNMIYSSIHQNW-----WVYTLLFTLA  345

Query  237  RVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSER  296
            R  PF  S +         AV P   G+ G YF        SAE+ +   A  LWE SER
Sbjct  346  R--PFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSAEAQNEVTARALWELSER  403

Query  297  LLAQ  300
            L+ +
Sbjct  404  LIQE  407



Lambda     K      H
   0.321    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 505781532318




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40