BLAST Search Results


BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0305c

Length=963
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|57116720|ref|YP_177715.1|  PPE family protein [Mycobacterium t...  1895    0.0   
gi|306970504|ref|ZP_07483165.1|  PPE family protein [Mycobacteriu...  1357    0.0   
gi|294995062|ref|ZP_06800753.1|  PPE family protein [Mycobacteriu...  1357    0.0   
gi|289748075|ref|ZP_06507453.1|  PPE family protein [Mycobacteriu...  1357    0.0   
gi|15839689|ref|NP_334726.1|  PPE family protein [Mycobacterium t...  1357    0.0   
gi|306806111|ref|ZP_07442779.1|  PPE family protein [Mycobacteriu...  1356    0.0   
gi|306779146|ref|ZP_07417483.1|  PPE family protein [Mycobacteriu...  1356    0.0   
gi|254549250|ref|ZP_05139697.1|  PPE family protein [Mycobacteriu...  1356    0.0   
gi|289752336|ref|ZP_06511714.1|  PPE family protein [Mycobacteriu...  1356    0.0   
gi|340625336|ref|YP_004743788.1|  ppe family protein [Mycobacteri...  1355    0.0   
gi|31791484|ref|NP_853977.1|  PPE family protein [Mycobacterium b...  1355    0.0   
gi|289441685|ref|ZP_06431429.1|  PPE family protein [Mycobacteriu...  1355    0.0   
gi|289748788|ref|ZP_06508166.1|  PPE family protein [Mycobacteriu...  1355    0.0   
gi|148821501|ref|YP_001286255.1|  PPE family protein [Mycobacteri...  1355    0.0   
gi|308231518|ref|ZP_07663878.1|  putative PPE family protein [Myc...  1354    0.0   
gi|339630379|ref|YP_004722021.1|  PPE family protein [Mycobacteri...  1353    0.0   
gi|339293362|gb|AEJ45473.1|  PPE family protein [Mycobacterium tu...  1353    0.0   
gi|289756370|ref|ZP_06515748.1|  LOW QUALITY PROTEIN: PPE family ...  1353    0.0   
gi|289445845|ref|ZP_06435589.1|  PPE family protein [Mycobacteriu...  1352    0.0   
gi|253797231|ref|YP_003030232.1|  PPE family protein [Mycobacteri...  1348    0.0   
gi|344218125|gb|AEM98755.1|  PPE family protein [Mycobacterium tu...  1348    0.0   
gi|298523783|ref|ZP_07011192.1|  PPE family protein [Mycobacteriu...  1346    0.0   
gi|121636220|ref|YP_976443.1|  PPE family protein [Mycobacterium ...  1328    0.0   
gi|289568217|ref|ZP_06448444.1|  PPE family protein [Mycobacteriu...  1122    0.0   
gi|289552558|ref|ZP_06441768.1|  PPE family protein [Mycobacteriu...  1106    0.0   
gi|183981653|ref|YP_001849944.1|  PPE family protein [Mycobacteri...   743    0.0   
gi|289445844|ref|ZP_06435588.1|  PPE family protein [Mycobacteriu...   708    0.0   
gi|148660070|ref|YP_001281593.1|  PPE family protein [Mycobacteri...   706    0.0   
gi|289756369|ref|ZP_06515747.1|  PPE family protein [Mycobacteriu...   706    0.0   
gi|57116719|ref|YP_177714.1|  PPE family protein [Mycobacterium t...   706    0.0   
gi|308231517|ref|ZP_07663877.1|  hypothetical protein TMAG_03673 ...   706    0.0   
gi|308376358|ref|ZP_07668254.1|  hypothetical protein TMHG_03315 ...   705    0.0   
gi|167967605|ref|ZP_02549882.1|  PPE family protein [Mycobacteriu...   705    0.0   
gi|289568216|ref|ZP_06448443.1|  PPE family protein [Mycobacteriu...   705    0.0   
gi|240171832|ref|ZP_04750491.1|  PPE family protein [Mycobacteriu...   673    0.0   
gi|289445843|ref|ZP_06435587.1|  PPE family protein [Mycobacteriu...   612    7e-173
gi|31791483|ref|NP_853976.1|  PPE family protein [Mycobacterium b...   611    2e-172
gi|289572891|ref|ZP_06453118.1|  PE family protein [Mycobacterium...   610    4e-172
gi|339293360|gb|AEJ45471.1|  PPE family protein [Mycobacterium tu...   610    5e-172
gi|183980666|ref|YP_001848957.1|  PPE family protein [Mycobacteri...   609    7e-172
gi|298523777|ref|ZP_07011186.1|  ppe family protein [Mycobacteriu...   605    1e-170
gi|240171835|ref|ZP_04750494.1|  PPE family protein [Mycobacteriu...   568    2e-159
gi|31794527|ref|NP_857020.1|  PPE family protein [Mycobacterium b...   567    4e-159
gi|240173399|ref|ZP_04752057.1|  PPE family protein [Mycobacteriu...   563    4e-158
gi|308376082|ref|ZP_07446012.2|  putative PPE family protein [Myc...   562    1e-157
gi|306801949|ref|ZP_07438617.1|  PPE family protein [Mycobacteriu...   561    2e-157
gi|183984588|ref|YP_001852879.1|  PPE family protein [Mycobacteri...   559    9e-157
gi|340625385|ref|YP_004743837.1|  PPE family protein [Mycobacteri...   556    7e-156
gi|240173413|ref|ZP_04752071.1|  PPE family protein [Mycobacteriu...   552    1e-154
gi|308379758|ref|ZP_07669042.1|  putative PPE family protein [Myc...   550    5e-154


>gi|57116720|ref|YP_177715.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148660071|ref|YP_001281594.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|167967606|ref|ZP_02549883.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|7478716|pir||B70524 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|38490171|emb|CAE55270.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|148504223|gb|ABQ72032.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=963

 Score = 1895 bits (4910),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 963/963 (100%), Positives = 963/963 (100%), Gaps = 0/963 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQ  840
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQ
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQ  840

Query  841  PGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRY  900
            PGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRY
Sbjct  841  PGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRY  900

Query  901  RPLHRPSDTDNRSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVG  960
            RPLHRPSDTDNRSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVG
Sbjct  901  RPLHRPSDTDNRSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVG  960

Query  961  LLQ  963
            LLQ
Sbjct  961  LLQ  963


>gi|306970504|ref|ZP_07483165.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|307078232|ref|ZP_07487402.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308359899|gb|EFP48750.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|308363801|gb|EFP52652.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=3186

 Score = 1357 bits (3511),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  694 bits (1792),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 489/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNS----------GLLHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NS          GLL    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GF  672
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GF
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
             ANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  670 bits (1729),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/651 (64%), Positives = 486/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVG LGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGTLGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2578


 Score =  630 bits (1624),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  610 bits (1574),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2520  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2579

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2580  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2638

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2639  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2688

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2689  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2748

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2749  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2808

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2809  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2868

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2869  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2928

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2929  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2988

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2989  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3048

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  3049  TGYLNTGDYNTGVANTGDVD  3068


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2865  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2924

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2925  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2984

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2985  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3044

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3045  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3102


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3083  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3130

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3131  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3173


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3000  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3059

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3060  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3119

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3120  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3176

Query  356   NT  357
              T
Sbjct  3177  GT  3178


>gi|294995062|ref|ZP_06800753.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|326906059|gb|EGE52992.1| PPE family protein [Mycobacterium tuberculosis W-148]
Length=3181

 Score = 1357 bits (3511),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1823),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  693 bits (1788),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  674 bits (1738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/646 (64%), Positives = 485/646 (76%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2573


 Score =  630 bits (1625),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  613 bits (1580),  Expect = 6e-173, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  2520  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  2579

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  2580  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  2638

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  2639  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  2688

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  N  + 
Sbjct  2689  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAG  2748

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  2749  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  2808

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  2809  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  2868

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  2869  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  2928

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  2929  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2988

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2989  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  3048

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  3049  TGDYNTGVANTGDVD  3063


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2860  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2919

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2920  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2979

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2980  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3039

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3040  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3097


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3078  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3125

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3126  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3168


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2995  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3054

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3055  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3114

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3115  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3171

Query  356   NT  357
              T
Sbjct  3172  GT  3173


>gi|289748075|ref|ZP_06507453.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289688603|gb|EFD56091.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=3181

 Score = 1357 bits (3511),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1823),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  693 bits (1788),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  674 bits (1738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/646 (64%), Positives = 486/646 (76%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG+GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGNGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2573


 Score =  628 bits (1619),  Expect = 2e-177, Method: Compositional matrix adjust.
 Identities = 391/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSG+GNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGNGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  613 bits (1580),  Expect = 6e-173, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  2520  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  2579

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  2580  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  2638

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  2639  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  2688

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  N  + 
Sbjct  2689  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAG  2748

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  2749  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  2808

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  2809  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  2868

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  2869  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  2928

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  2929  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2988

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2989  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  3048

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  3049  TGDYNTGVANTGDVD  3063


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2860  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2919

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2920  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2979

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2980  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3039

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3040  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3097


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3078  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3125

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3126  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3168


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2995  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3054

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3055  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3114

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3115  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3171

Query  356   NT  357
              T
Sbjct  3172  GT  3173


>gi|15839689|ref|NP_334726.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|254363274|ref|ZP_04979320.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|13879812|gb|AAK44540.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|134148788|gb|EBA40833.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|323721292|gb|EGB30348.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
 gi|339297007|gb|AEJ49117.1| PPE family protein [Mycobacterium tuberculosis CCDC5180]
Length=3186

 Score = 1357 bits (3511),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1823),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  693 bits (1788),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  672 bits (1733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2578


 Score =  630 bits (1625),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  611 bits (1575),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2520  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2579

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2580  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2638

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2639  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2688

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2689  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2748

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2749  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2808

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2809  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2868

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2869  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2928

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2929  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2988

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2989  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3048

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  3049  TGYLNTGDYNTGVANTGDVD  3068


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2865  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2924

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2925  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2984

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2985  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3044

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3045  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3102


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3083  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3130

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3131  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3173


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3000  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3059

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3060  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3119

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3120  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3176

Query  356   NT  357
              T
Sbjct  3177  GT  3178


>gi|306806111|ref|ZP_07442779.1| PPE family protein [Mycobacterium tuberculosis SUMu007]
 gi|306966309|ref|ZP_07478970.1| PPE family protein [Mycobacterium tuberculosis SUMu009]
 gi|308347367|gb|EFP36218.1| PPE family protein [Mycobacterium tuberculosis SUMu007]
 gi|308355942|gb|EFP44793.1| PPE family protein [Mycobacterium tuberculosis SUMu009]
Length=3186

 Score = 1356 bits (3510),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1823),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDVP  1779


 Score =  694 bits (1792),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 489/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  672 bits (1733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2578


 Score =  630 bits (1624),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DVPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  611 bits (1575),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2520  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2579

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2580  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2638

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2639  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2688

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2689  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2748

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2749  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2808

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2809  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2868

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2869  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2928

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2929  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2988

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2989  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3048

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  3049  TGYLNTGDYNTGVANTGDVD  3068


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2865  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2924

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2925  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2984

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2985  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3044

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3045  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3102


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3083  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3130

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3131  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3173


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3000  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3059

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3060  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3119

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3120  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3176

Query  356   NT  357
              T
Sbjct  3177  GT  3178


>gi|306779146|ref|ZP_07417483.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|306787301|ref|ZP_07425623.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308327856|gb|EFP16707.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308336013|gb|EFP24864.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
Length=3186

 Score = 1356 bits (3509),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  694 bits (1792),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 489/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  671 bits (1732),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2578


 Score =  629 bits (1623),  Expect = 6e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  608 bits (1569),  Expect = 1e-171, Method: Compositional matrix adjust.
 Identities = 414/740 (56%), Positives = 478/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2520  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2579

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2580  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2638

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2639  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2688

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2689  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2748

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2749  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2808

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2809  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2868

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2869  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2928

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2929  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2988

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2989  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3048

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  N GD+ 
Sbjct  3049  TGYLNTGDYNTGVANAGDVD  3068


 Score =  264 bits (674),  Expect = 8e-68, Method: Compositional matrix adjust.
 Identities = 156/239 (66%), Positives = 179/239 (75%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2865  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2924

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2925  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2984

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2985  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3044

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVAN G+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3045  GSGNTGYLNTGDYNTGVANAGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3102


 Score = 85.5 bits (210),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3083  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3130

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3131  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3173


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 53.1 bits (126),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 74/182 (41%), Positives = 94/182 (52%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3000  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3059

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G AN G  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3060  GVANAGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3119

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3120  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3176

Query  356   NT  357
              T
Sbjct  3177  GT  3178


>gi|254549250|ref|ZP_05139697.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297632792|ref|ZP_06950572.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|297729767|ref|ZP_06958885.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|306782933|ref|ZP_07421255.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|306796040|ref|ZP_07434342.1| PPE family protein [Mycobacterium tuberculosis SUMu006]
 gi|313657096|ref|ZP_07813976.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
 gi|308332211|gb|EFP21062.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308343506|gb|EFP32357.1| PPE family protein [Mycobacterium tuberculosis SUMu006]
Length=3186

 Score = 1356 bits (3509),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  694 bits (1792),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 489/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  671 bits (1732),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2578


 Score =  630 bits (1624),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  610 bits (1574),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2520  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2579

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2580  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2638

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2639  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2688

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2689  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2748

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2749  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2808

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2809  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2868

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2869  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2928

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2929  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2988

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2989  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3048

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  3049  TGYLNTGDYNTGVANTGDVD  3068


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2865  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2924

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2925  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2984

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2985  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3044

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3045  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3102


 Score = 85.5 bits (210),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3083  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3130

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3131  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3173


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3000  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3059

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3060  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3119

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3120  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3176

Query  356   NT  357
              T
Sbjct  3177  GT  3178


>gi|289752336|ref|ZP_06511714.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289692923|gb|EFD60352.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=3181

 Score = 1356 bits (3509),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  692 bits (1787),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  691 bits (1784),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/646 (64%), Positives = 485/646 (76%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPVIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2573


 Score =  630 bits (1624),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  616 bits (1588),  Expect = 7e-174, Method: Compositional matrix adjust.
 Identities = 416/735 (57%), Positives = 480/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  2520  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  2579

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  2580  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  2638

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  2639  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  2688

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  2689  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  2748

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  2749  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  2808

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  2809  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  2868

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  2869  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  2928

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  2929  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2988

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2989  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  3048

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  3049  TGDYNTGVANTGDVD  3063


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2860  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2919

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2920  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2979

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2980  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3039

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3040  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3097


 Score = 85.5 bits (210),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3078  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3125

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3126  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3168


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2995  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3054

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3055  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3114

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3115  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3171

Query  356   NT  357
              T
Sbjct  3172  GT  3173


>gi|340625336|ref|YP_004743788.1| ppe family protein [Mycobacterium canettii CIPT 140010059]
 gi|340003526|emb|CCC42647.1| ppe family protein [Mycobacterium canettii CIPT 140010059]
Length=3181

 Score = 1355 bits (3508),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  705 bits (1819),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNAGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  691 bits (1782),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/677 (63%), Positives = 487/677 (72%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG  SGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGATSGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  673 bits (1736),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/646 (64%), Positives = 485/646 (76%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2573


 Score =  629 bits (1621),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNAGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  614 bits (1583),  Expect = 3e-173, Method: Compositional matrix adjust.
 Identities = 409/705 (59%), Positives = 472/705 (67%), Gaps = 102/705 (14%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N+GLAN+G +N G GN G+FNVGF N+G++N+G ANLG+ ++G AN G ++IG ANTGS
Sbjct  2370  LNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGS  2429

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
              N+GF NTGS N+GIGLTG GQIGFGSFNSGSHNIGLFNSG GNVG FNSGTGN GIGN+
Sbjct  2430  ANIGFANTGSGNIGIGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNT  2489

Query  318   GTGNFG----------LGNTGSTNTGWFN----------TGDVNTGGFNPGSYNTGNFNT  357
             GT NFG          LGNTGSTNTG FN          TG +NTG FN GS NTG+FN 
Sbjct  2490  GTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVGNTGSINTGSFNTGSTNTGSFNL  2549

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G++NTGSFN+G+YNTGYFN GDYNTGVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG  
Sbjct  2550  GDHNTGSFNSGDYNTGYFNAGDYNTGVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLS  2609

Query  418   IALEIPAIPINAQLFSMPIH-----QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELP  472
               + IP IP    L S+PI       V+    +  TIPG ++         V  GP  + 
Sbjct  2610  TTITIPEIPYRYDL-SVPIDIPITGTVVATTPNSFTIPGFQIR--------VLLGPAAVL  2660

Query  473   QSTLTLPTVTITVGGPTTTIDG------NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSS  525
              + +  P +TI V      ID       ++ G  G   IP+ I I   PGFGNSTT PSS
Sbjct  2661  VNEMIGP-ITIDVN-QVIAIDSPIQQTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSS  2718

Query  526   GFFNAGAGTASGFGNFGGG-ASGFWNLASATSGL--------SGFGNVGALGSGVANVGN  576
             GFF+ GAG  SGFGNFG G  SGF N  +  SG         SG  N GAL SG+AN+GN
Sbjct  2719  GFFHTGAGHVSGFGNFGAGNMSGFGNFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGN  2778

Query  577   TISGLYNTSTSNLATPAFNSG----------LLHHSVGTMTLNFGLAN------------  614
             TISG+YNTST +LATPAF SG          L   + G +TLNFG+AN            
Sbjct  2779  TISGVYNTSTLDLATPAFGSGIANIGANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLG  2838

Query  615   ----------------------------VGGNNVGGANAGIFNVGLANLGDYNIGFGNLG  646
                                         +GGNN+G AN GIF++GLANLG YNIG  NLG
Sbjct  2839  SVNIGFVNTGDSNLGIGNLGDLNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLG  2898

Query  647   GDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLN  706
              DNLGF +AGSYNIGFAN GS+NLGFANTG  NIGFAN G+NNIG+GLTG+GQIG GSLN
Sbjct  2899  DDNLGFGNAGSYNIGFANFGSDNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLN  2958

Query  707   SGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFN  766
             SGS+NIGLFNSG GNIG FNSG+GN GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN
Sbjct  2959  SGSNNIGLFNSGSGNIGFFNSGTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFN  3018

Query  767   SGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
              GDLNTGS NPGS+NTG  N GS NTG  N G+Y+TG  NTGD+ 
Sbjct  3019  PGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYSTGVANTGDVD  3063


 Score =  264 bits (674),  Expect = 8e-68, Method: Compositional matrix adjust.
 Identities = 156/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2860  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2919

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2920  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2979

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2980  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3039

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDY+TGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3040  GSGNTGYLNTGDYSTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3097


 Score = 82.8 bits (203),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 55/107 (52%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3078  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3125

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LAT +F SG+
Sbjct  3126  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATASFVSGI  3168


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 52.4 bits (124),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 65/159 (41%), Positives = 85/159 (54%), Gaps = 13/159 (8%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G ++ 
Sbjct  2995  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYST  3054

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3055  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3114

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFN  336
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N
Sbjct  3115  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLN  3153


>gi|31791484|ref|NP_853977.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|289572892|ref|ZP_06453119.1| PE family protein [Mycobacterium tuberculosis K85]
 gi|31617070|emb|CAD93177.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
 gi|289537323|gb|EFD41901.1| PE family protein [Mycobacterium tuberculosis K85]
Length=1985

 Score = 1355 bits (3508),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  708 bits (1828),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  695 bits (1794),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  449 bits (1155),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 277/464 (60%), Positives = 334/464 (72%), Gaps = 38/464 (8%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNL  650
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNL
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNL  1981


 Score = 75.1 bits (183),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGLA------------NLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 57.0 bits (136),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 29/45 (65%), Positives = 35/45 (78%), Gaps = 0/45 (0%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL  242
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNL L
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLAL  1983


 Score = 41.6 bits (96),  Expect = 0.73, Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 32/46 (70%), Gaps = 0/46 (0%)

Query  227   SYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGI  272
             + NLG ANLGS+N G  N G  ++G AN G+ N+GFGN G +N+ +
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLAL  1983


>gi|289441685|ref|ZP_06431429.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289414604|gb|EFD11844.1| PPE family protein [Mycobacterium tuberculosis T46]
Length=3181

 Score = 1355 bits (3507),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 808/809 (99%), Positives = 808/809 (99%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANV ANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVAANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  692 bits (1787),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGT----------GNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GT          GNFG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNS----------GLLHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NS          GLL    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GF  672
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GF
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
             ANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  689 bits (1777),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/646 (64%), Positives = 484/646 (75%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPVIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQI FGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIEFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2573


 Score =  630 bits (1624),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  613 bits (1581),  Expect = 5e-173, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQI FGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIEFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  2520  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  2579

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  2580  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  2638

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  2639  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  2688

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  2689  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  2748

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  2749  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  2808

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  2809  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  2868

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  2869  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  2928

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  2929  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2988

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2989  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  3048

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  3049  TGDYNTGVANTGDVD  3063


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2860  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2919

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2920  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2979

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2980  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3039

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3040  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3097


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3078  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3125

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3126  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3168


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.8 bits (133),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 71/186 (39%), Positives = 92/186 (50%), Gaps = 10/186 (5%)

Query  641   GFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQI  700
             GFGN+GG+      +G +N+  A +G +  G  N G    G AN+G+   GI  T    +
Sbjct  2285  GFGNVGGN-----TSGLWNLASAASGVS--GLLNVGALGSGVANVGNTISGIYNTSPLDL  2337

Query  701   GFGSLNSGSHNI-GLFNSGDGNIGLFNSGSGNFGIG--NAGTGNWGIGNSGAGNFGIGNA  757
             G  +  SG  NI GL   G G   L  +G GN  +G  N G  N+GIGN+G  N G  N 
Sbjct  2338  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANV  2397

Query  758   GSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEH  817
             G+ N GL N G+ + G  N G+Y+ G  NTGS N G  N G+ N G   TG  Q   G  
Sbjct  2398  GNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIEFGSF  2457

Query  818   RQYQHR  823
                 H 
Sbjct  2458  NSGSHN  2463


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2995  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3054

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3055  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3114

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3115  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3171

Query  356   NT  357
              T
Sbjct  3172  GT  3173


>gi|289748788|ref|ZP_06508166.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289689375|gb|EFD56804.1| PPE family protein [Mycobacterium tuberculosis T92]
Length=3181

 Score = 1355 bits (3507),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 808/809 (99%), Positives = 808/809 (99%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANV ANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVAANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  706 bits (1821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1686

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1687  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1746

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1747  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1779


 Score =  692 bits (1787),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGT----------GNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GT          GNFG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNS----------GLLHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NS          GLL    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GF  672
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GF
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
             ANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  689 bits (1777),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/646 (64%), Positives = 484/646 (75%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1939  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1998

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1999  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2058

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2059  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2118

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2119  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2177

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2178  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2237

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2238  TAINISATAGLGPITIPVIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2297

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2298  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2357

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2358  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2417

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQI FGS NSGSHNIGLF
Sbjct  2418  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIEFGSFNSGSHNIGLF  2467

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2468  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2527

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2528  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2573


 Score =  629 bits (1623),  Expect = 6e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1544  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1603

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1604  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1663

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1664  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1713

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1714  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1773

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1774  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1827

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1828  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1877

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1878  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1937

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1938  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1997

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1998  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2047

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2048  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2097

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2098  TGSFNTGGFNAGNTNTGHFNTGN  2120


 Score =  613 bits (1581),  Expect = 5e-173, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2342  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2399

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQI FGSFNS
Sbjct  2400  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIEFGSFNS  2459

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2460  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2519

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  2520  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  2579

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  2580  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  2638

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  2639  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  2688

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  2689  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  2748

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  2749  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  2808

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  2809  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  2868

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  2869  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  2928

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  2929  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2988

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2989  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  3048

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  3049  TGDYNTGVANTGDVD  3063


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2860  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2919

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2920  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2979

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2980  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3039

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3040  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3097


 Score = 81.6 bits (200),  Expect = 6e-13, Method: Compositional matrix adjust.
 Identities = 54/107 (51%), Positives = 68/107 (64%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3078  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3125

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ + GALGSGVANVGNTIS   N S  +LATP F SG+
Sbjct  3126  ----AGLSGYLDTGALGSGVANVGNTISDWLNASALDLATPGFLSGI  3168


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.8 bits (133),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 71/186 (39%), Positives = 92/186 (50%), Gaps = 10/186 (5%)

Query  641   GFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQI  700
             GFGN+GG+      +G +N+  A +G +  G  N G    G AN+G+   GI  T    +
Sbjct  2285  GFGNVGGN-----TSGLWNLASAASGVS--GLLNVGALGSGVANVGNTISGIYNTSPLDL  2337

Query  701   GFGSLNSGSHNI-GLFNSGDGNIGLFNSGSGNFGIG--NAGTGNWGIGNSGAGNFGIGNA  757
             G  +  SG  NI GL   G G   L  +G GN  +G  N G  N+GIGN+G  N G  N 
Sbjct  2338  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANV  2397

Query  758   GSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEH  817
             G+ N GL N G+ + G  N G+Y+ G  NTGS N G  N G+ N G   TG  Q   G  
Sbjct  2398  GNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIEFGSF  2457

Query  818   RQYQHR  823
                 H 
Sbjct  2458  NSGSHN  2463


 Score = 51.6 bits (122),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 73/182 (41%), Positives = 94/182 (52%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2995  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3054

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3055  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3114

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  ++G    G+ N G+T + W N    D+ T GF  G    GNF
Sbjct  3115  AGSVSGFVNSGAGLSGYLDTGALGSGVANVGNTISDWLNASALDLATPGFLSG---IGNF  3171

Query  356   NT  357
              T
Sbjct  3172  GT  3173


>gi|148821501|ref|YP_001286255.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|148720028|gb|ABR04653.1| PPE family protein [Mycobacterium tuberculosis F11]
Length=3166

 Score = 1355 bits (3507),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  694 bits (1790),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 489/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNSGL----------LHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NSGL          L    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN--------  674
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGFAN        
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  675   --TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
               TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  685 bits (1768),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 420/673 (63%), Positives = 494/673 (74%), Gaps = 41/673 (6%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1092  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1151

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1152  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1211

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1212  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1271

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1272  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1329

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1330  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1389

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1390  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1446

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  602   SVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDN----------LG  651
             S GTM LN GLAN G  NVG AN G +N+G ANLG  N G  N+GG+N          +G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  652   FAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHN  711
              A+ GSYNIGF N G +NLGFANTG NNIGFAN GSNNIGIGLTG GQIGFGSLNSGS N
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGN  1626

Query  712   IGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG----------NFGIGNAGSTN  761
             IGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+           N GIGN GS N
Sbjct  1627  IGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTGIGNTGSFN  1686

Query  762   TGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             TG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+ G+  +G+ Q   G H    
Sbjct  1687  TGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALA  1746

Query  822   HRRFHLRQPQQRP  834
                  L      P
Sbjct  1747  IPEIALTFGVDIP  1759


 Score =  671 bits (1731),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1919  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1978

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1979  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2038

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2039  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2098

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2099  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2157

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2158  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2217

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2218  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2277

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2278  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2337

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2338  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2397

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2398  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2447

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2448  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2507

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2508  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2558


 Score =  610 bits (1573),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 409/710 (58%), Positives = 471/710 (67%), Gaps = 107/710 (15%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N+GLAN+G +N G GN G+FNVGF N+G++N+G ANLG+ ++G AN G ++IG ANTGS
Sbjct  2350  LNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGS  2409

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
              N+GF NTGS N+GIGLTG GQIGFGSFNSGSHNIGLFNSG GNVG FNSGTGN GIGN+
Sbjct  2410  ANIGFANTGSGNIGIGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNT  2469

Query  318   GTGNFG----------LGNTGSTNTGWFN---------------TGDVNTGGFNPGSYNT  352
             GT NFG          LGNTGSTNTG FN               TG +NTG FN GS NT
Sbjct  2470  GTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVGNTGSINTGSINTGSFNTGSTNT  2529

Query  353   GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQG  412
             G+FN G++NTGSFN+G+YNTGYFN GDYNTGVANTGNVNTGAFI+GNYSNG  WRGDYQG
Sbjct  2530  GSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANTGNVNTGAFISGNYSNGFFWRGDYQG  2589

Query  413   LIGADIALEIPAIPINAQLFSMPIH-----QVMVMPGSVMTIPGMRLPFTSIVPFVVYYG  467
             LIG    + IP IP    L S+PI       V+    +  TIPG ++         V  G
Sbjct  2590  LIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVATTPNSFTIPGFQIR--------VLLG  2640

Query  468   PVELPQSTLTLPTVTITVGGPTTTIDG------NLTGMVGGVSIPL-IKIPAAPGFGNST  520
             P  +  + +  P +TI V      ID       ++ G  G   IP+ I I   PGFGNST
Sbjct  2641  PAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISMVGTGGFGPIPIGISIGGTPGFGNST  2698

Query  521   TSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASATSGL--------SGFGNVGALGSGV  571
             T PSSGFF+ GAG  SGFGNFG G  SG  N  +  SG         SG  N GAL SG+
Sbjct  2699  TGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAGNSGFFNAGGLGNSGLLNFGALQSGL  2758

Query  572   ANVGNTISGLYNTSTSNLATPAFNSG----------LLHHSVGTMTLNFGLAN-------  614
             AN+GNTISG+YNTST +LATPAF SG          L   + G +TLNFG+AN       
Sbjct  2759  ANLGNTISGVYNTSTLDLATPAFGSGIANIGANLAGLFLDNTGNLTLNFGVANQGGLNAG  2818

Query  615   ---------------------------------VGGNNVGGANAGIFNVGLANLGDYNIG  641
                                              +GGNN+G AN GIF++GLANLG YNIG
Sbjct  2819  IGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIG  2878

Query  642   FGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIG  701
               NLG DNLGF +AGSYNIGFAN GS+NLGFANTG  NIGFAN G+NNIG+GLTG+GQIG
Sbjct  2879  LANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIG  2938

Query  702   FGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTN  761
              GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N GTGN+G+ NSG  N GIGNAGSTN
Sbjct  2939  IGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTN  2998

Query  762   TGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
             TG+FN GDLNTGS NPGS+NTG  N GS NTG  N G+YNTG  NTGD+ 
Sbjct  2999  TGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNTGVANTGDVD  3048


 Score =  608 bits (1568),  Expect = 2e-171, Method: Compositional matrix adjust.
 Identities = 401/700 (58%), Positives = 476/700 (68%), Gaps = 92/700 (13%)

Query  156   AGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGAN-------  208
             A A++  S L+        LA +   ++     +    +   FN GLAN+  +       
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  209   -------NVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI-----------  250
                    N+G  N G  NVG  NLG YN+GFANLGS N G AN+GG+NI           
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  251   -------------------GFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHN  291
                                GFANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS N
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGN  1626

Query  292   IGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYN  351
             IGLFNSGSGN+G FNSG GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG        
Sbjct  1627  IGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------  1678

Query  352   TGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQ  411
              G  NTG++NTGSFN G+ NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQ
Sbjct  1679  IG--NTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQ  1736

Query  412   GLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPV  469
             GLIG   AL IP I +   +  +PIH  + +   V+T+ G      SIV     + + P+
Sbjct  1737  GLIGLHAALAIPEIALTFGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPI  1790

Query  470   ELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFN  529
              +P   +TLPT  ITVGGPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN
Sbjct  1791  IIPTINITLPTAAITVGGPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFN  1850

Query  530   AGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNL  589
             +GAG+          ASGF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L
Sbjct  1851  SGAGS----------ASGFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDL  1900

Query  590   ATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDN  649
              TPAF SGL+   +GTMTLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DN
Sbjct  1901  VTPAFASGLMRDGMGTMTLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDN  1960

Query  650   LGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGS  709
             LGFA+ GSYNIG ANTGSNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS
Sbjct  1961  LGFANLGSYNIGVANTGSNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGS  2010

Query  710   HNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGD  769
              NIGLFNSGDGNIG FNSG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD
Sbjct  2011  GNIGLFNSGDGNIGFFNSGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGD  2060

Query  770   LNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
              NTG  NPG++NTG+ NTGS NTGGFNAGN NTG+FNTG+
Sbjct  2061  GNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNTGN  2100


 Score =  265 bits (678),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2845  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2904

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2905  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2964

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2965  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3024

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3025  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3082


 Score = 85.5 bits (210),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3063  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3110

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3111  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3153


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2980  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3039

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3040  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3099

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3100  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3156

Query  356   NT  357
              T
Sbjct  3157  GT  3158


>gi|308231518|ref|ZP_07663878.1| putative PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308216994|gb|EFO76393.1| putative PPE family protein [Mycobacterium tuberculosis SUMu001]
Length=906

 Score = 1354 bits (3505),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  328 bits (841),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 186/296 (63%), Positives = 218/296 (74%), Gaps = 20/296 (6%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608  LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258  NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
            NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668  NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308  GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
            G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728  GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358  GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
            G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788  GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418  IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQ  473
            I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  +     +  P 
Sbjct  848  IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVTVIFSDPSISTPS  903


 Score = 76.3 bits (186),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGLA------------NLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 61.6 bits (148),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 76/195 (39%), Positives = 95/195 (49%), Gaps = 17/195 (8%)

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GF N G+    GF N G    GF N+ S   G+ G    G +G G  N G+   GL+N+ 
Sbjct  661  GFANTGSNNL-GFANTGDNNIGFANIGSNNIGI-GLTGSGQIGFGSLNSGSHNIGLFNSG  718

Query  586  TSNLATPAFNSGLLHHSVGTM-TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGN  644
              N+    FNSG  +  +G   T N+G+ N G  N G  NAG  N GL N GD N G  N
Sbjct  719  DGNIGL--FNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776

Query  645  LGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGS  704
             G  N G  + GS N G  N G+ N G+ NTGD N G AN            +G I  G+
Sbjct  777  PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMAN------------TGNINTGA  824

Query  705  LNSGSHNIGLFNSGD  719
              SG+H+ GL   GD
Sbjct  825  FISGNHSNGLLWRGD  839


>gi|339630379|ref|YP_004722021.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339329735|emb|CCC25379.1| PPE family protein [Mycobacterium africanum GM041182]
Length=964

 Score = 1353 bits (3502),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  383 bits (983),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 221/358 (62%), Positives = 263/358 (74%), Gaps = 26/358 (7%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608  LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258  NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
            NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668  NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308  GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
            G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728  GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358  GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
            G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788  GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418  IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
            I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848  IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473  QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNA  530
               +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+
Sbjct  907  VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNS  964


 Score = 76.3 bits (186),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGLA------------NLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 61.6 bits (148),  Expect = 8e-07, Method: Compositional matrix adjust.
 Identities = 76/195 (39%), Positives = 95/195 (49%), Gaps = 17/195 (8%)

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GF N G+    GF N G    GF N+ S   G+ G    G +G G  N G+   GL+N+ 
Sbjct  661  GFANTGSNNL-GFANTGDNNIGFANIGSNNIGI-GLTGSGQIGFGSLNSGSHNIGLFNSG  718

Query  586  TSNLATPAFNSGLLHHSVGTM-TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGN  644
              N+    FNSG  +  +G   T N+G+ N G  N G  NAG  N GL N GD N G  N
Sbjct  719  DGNIGL--FNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776

Query  645  LGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGS  704
             G  N G  + GS N G  N G+ N G+ NTGD N G AN            +G I  G+
Sbjct  777  PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMAN------------TGNINTGA  824

Query  705  LNSGSHNIGLFNSGD  719
              SG+H+ GL   GD
Sbjct  825  FISGNHSNGLLWRGD  839


>gi|339293362|gb|AEJ45473.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
Length=1735

 Score = 1353 bits (3502),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  696 bits (1796),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  967   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1026

Query  593   AFNS----------GLLHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NS          GLL    GT  +N GLAN                    +G NNVG 
Sbjct  1027  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1086

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GF  672
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GF
Sbjct  1087  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1146

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
             ANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1147  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1206

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1207  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1256

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1257  GGFNPGNTNTGYLNIGN  1273


 Score =  611 bits (1575),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 371/596 (63%), Positives = 428/596 (72%), Gaps = 71/596 (11%)

Query  190   AGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGS------------  237
              G  S  GFN G A +G NNVG GN G+F+VG  NLGSYN+GF NLG             
Sbjct  1064  VGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYN  1123

Query  238   --------DNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS  289
                     DNLG AN GG NIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS
Sbjct  1124  IGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS  1183

Query  290   HNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGS  349
              NIGLFNSGS N+G FNSG+GNFGI NSG+ N G+GNTG+TNTG FN+GDVNTG FNPGS
Sbjct  1184  GNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGS  1243

Query  350   YNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGD  409
             +NTG+FNTG++NTG FN GN NTGY N G+YNTG+ANTG+V+TGAFI GNYSNG+   GD
Sbjct  1244  FNTGSFNTGSFNTGGFNPGNTNTGYLNIGNYNTGIANTGDVDTGAFITGNYSNGLFLSGD  1303

Query  410   YQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLP------FTSIVPFV  463
             YQGL+G ++ +++P +PI+  + ++PI   +      +T+ G+ +P       +SI    
Sbjct  1304  YQGLVGLNLVIDMP-LPISLGV-NIPIDIPITASAGNITLMGVTIPPTGDIVLSSIAGQR  1361

Query  464   VYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSP  523
              ++GP+ +P  T+  PT T+ +GGP T I   +TG  G + IPLI IPAAPGFGNSTT+P
Sbjct  1362  AHFGPITIPNITVVGPTTTVAIGGPNTAIT--ITGG-GAIRIPLISIPAAPGFGNSTTNP  1418

Query  524   SSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYN  583
             SSGFFN GAG ASGFGNFGG  SGFWNLASATSG SG  NVGALGSG+ANVG T+SG YN
Sbjct  1419  SSGFFNTGAGGASGFGNFGGANSGFWNLASATSGASGLLNVGALGSGLANVGTTVSGFYN  1478

Query  584   TSTSNLATPAFNS----------GLLHHSVGTMTLNFGL---------------------  612
             TSTS+LATPAFNS          GLL  S GTM LN GL                     
Sbjct  1479  TSTSDLATPAFNSGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFA  1538

Query  613   ---------ANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFA  663
                      AN+GGNN+GGAN GIF++GLANLG YNIGFGN G DNLGF + GSYN+GF 
Sbjct  1539  NLGSANFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFG  1598

Query  664   NTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGD  719
             N G++NLGFANTG NNIGFAN GSNNIGIGLTG GQIGFGSLNSGS NIGLFNSG 
Sbjct  1599  NLGNDNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGQ  1654


 Score =  106 bits (265),  Expect = 2e-20, Method: Compositional matrix adjust.
 Identities = 80/166 (49%), Positives = 103/166 (63%), Gaps = 4/166 (2%)

Query  176   AGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANL  235
             +GL+   TS A            NLGLAN G  NVG  N+G +N+GF NLGS N G AN+
Sbjct  1491  SGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANI  1550

Query  236   GSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLF  295
             G +N+G AN G  +IG AN GS N+GFGN G +N+G G  G+  +GFG  N G+ N+G  
Sbjct  1551  GGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFG--NLGNDNLGFA  1608

Query  296   NSGSGNVGLFNSGTGNFGIGNSGTGNFGLG--NTGSTNTGWFNTGD  339
             N+GS N+G  N+G+ N GIG +G G  G G  N+GS N G FN+G 
Sbjct  1609  NTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGQ  1654


 Score =  102 bits (254),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 79/207 (39%), Positives = 100/207 (49%), Gaps = 64/207 (30%)

Query  156   AGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANV----------  205
             A A++  S L+        LA +   ++     +    +   FN GLAN+          
Sbjct  1447  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1506

Query  206   ---------------------------------------GANNVGNGNV-----GVFNVG  221
                                                    G+ N+G  N+     G+F++G
Sbjct  1507  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1566

Query  222   FGNLGSYNLGFANLGSDNLGLANLGGHNI----------GFANTGSNNVGFGNTGSNNVG  271
               NLGSYN+GF N G DNLG  NLG +N+          GFANTGSNN+GF NTGSNN+G
Sbjct  1567  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1626

Query  272   IGLTGNGQIGFGSFNSGSHNIGLFNSG  298
             IGLTG+GQIGFGS NSGS NIGLFNSG
Sbjct  1627  IGLTGDGQIGFGSLNSGSGNIGLFNSG  1653


 Score = 75.1 bits (183),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGLA------------NLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 72.0 bits (175),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 80/192 (42%), Positives = 103/192 (54%), Gaps = 7/192 (3%)

Query  619   NVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDN  678
             N GGAN+G +N+  A  G    G  N+G    G A+ G+   GF NT +++L    T   
Sbjct  1435  NFGGANSGFWNLASATSGAS--GLLNVGALGSGLANVGTTVSGFYNTSTSDLA---TPAF  1489

Query  679   NIGFANIGSNNIGI--GLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
             N G ANI ++  G+    TG+  +  G  N G+ N+G+ N GD NIG  N GS NFG  N
Sbjct  1490  NSGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSAN  1549

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              G  N G  N+G  + G+ N GS N G  N GD N G  N GSYN G  N G+ N G  N
Sbjct  1550  IGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFAN  1609

Query  797   AGNYNTGYFNTG  808
              G+ N G+ NTG
Sbjct  1610  TGSNNIGFANTG  1621


 Score = 70.5 bits (171),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 88/239 (37%), Positives = 110/239 (47%), Gaps = 51/239 (21%)

Query  181   RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGV-------FNVGFGNLGS------  227
              L SA + A+G  +      GLANVG    G  N          FN G  N+ +      
Sbjct  1445  NLASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLL  1504

Query  228   --------YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQ  279
                      NLG AN G+ N+G+ANLG +NIGFAN GS N                    
Sbjct  1505  RDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSAN--------------------  1544

Query  280   IGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGD  339
               FGS N G +NIG  N+G  ++GL N G+ N G GN G  N G GN GS N G+ N G+
Sbjct  1545  --FGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGN  1602

Query  340   VNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAG  398
              N G  N GS N G  NTG+ N G    G+   G+        G  N+G+ N G F +G
Sbjct  1603  DNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGF--------GSLNSGSGNIGLFNSG  1653


>gi|289756370|ref|ZP_06515748.1| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
T85]
 gi|289711934|gb|EFD75946.1| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
T85]
Length=963

 Score = 1353 bits (3502),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  382 bits (982),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 221/357 (62%), Positives = 262/357 (74%), Gaps = 26/357 (7%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608  LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258  NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
            NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668  NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308  GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
            G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728  GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358  GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
            G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788  GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418  IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
            I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848  IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473  QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFN  529
               +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN
Sbjct  907  VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFN  963


 Score = 76.6 bits (187),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGLA------------NLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 61.6 bits (148),  Expect = 8e-07, Method: Compositional matrix adjust.
 Identities = 76/195 (39%), Positives = 95/195 (49%), Gaps = 17/195 (8%)

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GF N G+    GF N G    GF N+ S   G+ G    G +G G  N G+   GL+N+ 
Sbjct  661  GFANTGSNNL-GFANTGDNNIGFANIGSNNIGI-GLTGSGQIGFGSLNSGSHNIGLFNSG  718

Query  586  TSNLATPAFNSGLLHHSVGTM-TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGN  644
              N+    FNSG  +  +G   T N+G+ N G  N G  NAG  N GL N GD N G  N
Sbjct  719  DGNIGL--FNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776

Query  645  LGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGS  704
             G  N G  + GS N G  N G+ N G+ NTGD N G AN            +G I  G+
Sbjct  777  PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMAN------------TGNINTGA  824

Query  705  LNSGSHNIGLFNSGD  719
              SG+H+ GL   GD
Sbjct  825  FISGNHSNGLLWRGD  839


>gi|289445845|ref|ZP_06435589.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289418803|gb|EFD16004.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=982

 Score = 1352 bits (3499),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/809 (100%), Positives = 809/809 (100%), Gaps = 0/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809


 Score =  402 bits (1033),  Expect = 2e-109, Method: Compositional matrix adjust.
 Identities = 232/370 (63%), Positives = 275/370 (75%), Gaps = 26/370 (7%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608  LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258  NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
            NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668  NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308  GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
            G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728  GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358  GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
            G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  788  GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  847

Query  418  IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
            I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  848  IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  906

Query  473  QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
               +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  907  VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  966

Query  533  GTASGFGNFG  542
            G+ASGFGNFG
Sbjct  967  GSASGFGNFG  976


 Score = 76.6 bits (187),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGLA------------NLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 61.6 bits (148),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 76/195 (39%), Positives = 95/195 (49%), Gaps = 17/195 (8%)

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GF N G+    GF N G    GF N+ S   G+ G    G +G G  N G+   GL+N+ 
Sbjct  661  GFANTGSNNL-GFANTGDNNIGFANIGSNNIGI-GLTGSGQIGFGSLNSGSHNIGLFNSG  718

Query  586  TSNLATPAFNSGLLHHSVGTM-TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGN  644
              N+    FNSG  +  +G   T N+G+ N G  N G  NAG  N GL N GD N G  N
Sbjct  719  DGNIGL--FNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776

Query  645  LGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGS  704
             G  N G  + GS N G  N G+ N G+ NTGD N G AN            +G I  G+
Sbjct  777  PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMAN------------TGNINTGA  824

Query  705  LNSGSHNIGLFNSGD  719
              SG+H+ GL   GD
Sbjct  825  FISGNHSNGLLWRGD  839


>gi|253797231|ref|YP_003030232.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|253318734|gb|ACT23337.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|328457018|gb|AEB02441.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=3196

 Score = 1348 bits (3490),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/819 (99%), Positives = 809/819 (99%), Gaps = 10/819 (1%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  ----------NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
                      NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  819


 Score =  706 bits (1823),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1102  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1161

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1162  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1221

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1222  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1281

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1282  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1339

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1340  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1399

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1400  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1456

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1457  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1516

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1517  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1576

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1577  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1636

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1637  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1696

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1697  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1756

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1757  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1789


 Score =  688 bits (1776),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/687 (63%), Positives = 490/687 (72%), Gaps = 86/687 (12%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGS----------FNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWR  407
             G+ NTGS          FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWR
Sbjct  788   GSVNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWR  847

Query  408   GDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYG  467
             GD QGLI   I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++G
Sbjct  848   GDNQGLIDLAIGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFG  906

Query  468   PVEL-----PQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTS  522
             PV++     P   +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST  
Sbjct  907   PVDIDPFTVPVIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGG  966

Query  523   PSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLY  582
              SSGFFN+GAG+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+Y
Sbjct  967   LSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIY  1026

Query  583   NTSTSNLATPAFNSGL----------LHHSVGTMTLNFGLAN------------------  614
             N  TS+L+TPA NSGL          L    GT  +N GLAN                  
Sbjct  1027  NVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGG  1086

Query  615   --VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGF  672
               +G NNVG  N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NLGF
Sbjct  1087  ATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGF  1146

Query  673   AN----------TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNI  722
             AN          TG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NI
Sbjct  1147  ANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNI  1206

Query  723   GLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNT  782
             G FNSGSGNF          GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NT
Sbjct  1207  GFFNSGSGNF----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNT  1256

Query  783   GSVNTGSVNTGGFNAGNYNTGYFNTGD  809
             GS NTGS NTGGFN GN NTGY N G+
Sbjct  1257  GSFNTGSFNTGGFNPGNTNTGYLNIGN  1283


 Score =  672 bits (1733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1949  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  2008

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  2009  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2068

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2069  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2128

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2129  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2187

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2188  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2247

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2248  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2307

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2308  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2367

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2368  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2427

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2428  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2477

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2478  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2537

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2538  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2588


 Score =  630 bits (1624),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1554  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1613

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1614  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1673

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1674  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1723

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1724  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1783

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1784  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1837

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1838  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1887

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1888  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1947

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1948  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  2007

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  2008  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2057

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2058  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2107

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2108  TGSFNTGGFNAGNTNTGHFNTGN  2130


 Score =  611 bits (1575),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2352  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2409

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2410  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2469

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2470  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2529

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2530  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2589

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2590  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2648

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2649  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2698

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2699  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2758

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2759  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2818

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2819  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2878

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2879  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2938

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2939  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2998

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2999  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3058

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  3059  TGYLNTGDYNTGVANTGDVD  3078


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2875  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2934

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2935  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2994

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2995  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3054

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3055  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3112


 Score = 85.5 bits (210),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3093  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3140

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3141  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3183


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 7e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3010  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3069

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3070  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3129

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3130  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3186

Query  356   NT  357
              T
Sbjct  3187  GT  3188


>gi|344218125|gb|AEM98755.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=3191

 Score = 1348 bits (3489),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 809/819 (99%), Positives = 809/819 (99%), Gaps = 10/819 (1%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780

Query  781  ----------NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
                      NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  781  NTGSVNTGSVNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  819


 Score =  694 bits (1790),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/693 (62%), Positives = 498/693 (72%), Gaps = 66/693 (9%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1102  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1161

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1162  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1221

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG      FN GN NTGY N 
Sbjct  1222  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTG-----GFNPGNTNTGYLNI  1276

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1277  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1334

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1335  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1394

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1395  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1451

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1452  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1511

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1512  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1571

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1572  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1631

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1632  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1691

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1692  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1751

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1752  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1784


 Score =  681 bits (1756),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/708 (61%), Positives = 493/708 (70%), Gaps = 91/708 (12%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  608   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  668   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  728   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787

Query  358   GNYNTGS----------FNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWR  407
             G+ NTGS          FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWR
Sbjct  788   GSVNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWR  847

Query  408   GDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYG  467
             GD QGLI   I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++G
Sbjct  848   GDNQGLIDLAIGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFG  906

Query  468   PVEL-----PQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTS  522
             PV++     P   +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST  
Sbjct  907   PVDIDPFTVPVIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGG  966

Query  523   PSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLY  582
              SSGFFN+GAG+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+Y
Sbjct  967   LSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIY  1026

Query  583   NTSTSNLATPAFNS----------GLLHHSVGTMTLNFGLAN------------------  614
             N  TS+L+TPA NS          GLL    GT  +N GLAN                  
Sbjct  1027  NVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGG  1086

Query  615   --VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL--  670
               +G NNVG  N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL  
Sbjct  1087  ATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGF  1146

Query  671   --------GFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNI  722
                     GFANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NI
Sbjct  1147  ANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNI  1206

Query  723   GLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNT  782
             G FNSGSGNF          GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NT
Sbjct  1207  GFFNSGSGNF----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNT  1256

Query  783   GSVNT-----GSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRF  825
             GS NT     G+ NTG  N GNYNTG  NTGD+         Y +  F
Sbjct  1257  GSFNTGGFNPGNTNTGYLNIGNYNTGIANTGDVDTGAFITGNYSNGLF  1304


 Score =  671 bits (1732),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1944  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  2003

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  2004  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2063

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2064  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2123

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2124  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2182

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2183  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2242

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2243  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2302

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2303  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2362

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2363  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2422

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2423  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2472

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2473  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2532

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2533  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2583


 Score =  629 bits (1623),  Expect = 5e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1549  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1608

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1609  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1668

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1669  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1718

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1719  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1778

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1779  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1832

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1833  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1882

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1883  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1942

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1943  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  2002

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  2003  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2052

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2053  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2102

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2103  TGSFNTGGFNAGNTNTGHFNTGN  2125


 Score =  610 bits (1574),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2347  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2404

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2405  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2464

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2465  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2524

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2525  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2584

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2585  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2643

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2644  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2693

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2694  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2753

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2754  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2813

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2814  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2873

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2874  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2933

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2934  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2993

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2994  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  3053

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  3054  TGYLNTGDYNTGVANTGDVD  3073


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2870  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2929

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2930  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2989

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2990  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3049

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3050  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3107


 Score = 85.5 bits (210),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3088  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3135

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3136  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3178


 Score = 74.3 bits (181),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 64/151 (43%), Positives = 80/151 (53%), Gaps = 20/151 (13%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  226  GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273

Query  736  NAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
              G G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  
Sbjct  274  LTGNGQIG--------FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLG  325

Query  796  NAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
            N G+ NTG+FNTGD+         Y    F+
Sbjct  326  NTGSTNTGWFNTGDVNTGGFNPGSYNTGNFN  356


 Score = 55.1 bits (131),  Expect = 7e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  3005  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3064

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3065  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3124

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3125  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3181

Query  356   NT  357
              T
Sbjct  3182  GT  3183


>gi|298523783|ref|ZP_07011192.1| PPE family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298493577|gb|EFI28871.1| PPE family protein [Mycobacterium tuberculosis 94_M4241A]
Length=3178

 Score = 1346 bits (3483),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 806/809 (99%), Positives = 806/809 (99%), Gaps = 3/809 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNG   FGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNG---FGSFNSGSHNIGLFNSGSG  297

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  298  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  357

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  358  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  417

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  418  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  477

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  478  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  537

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  538  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  597

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  598  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  657

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  658  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  717

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  718  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  777

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  778  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  806


 Score =  706 bits (1823),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1089  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1148

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1149  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1208

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1209  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1268

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1269  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1326

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1327  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1386

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1387  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1443

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1444  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1503

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1504  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1563

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1564  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1623

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1624  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1683

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1684  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1743

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1744  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1776


 Score =  693 bits (1789),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  605   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  664

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  665   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  724

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  725   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  784

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  785   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  844

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  845   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  903

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  904   VMRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  963

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  964   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1023

Query  593   AFNS----------GLLHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NS          GLL    GT  +N GLAN                    +G NNVG 
Sbjct  1024  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1083

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GF  672
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GF
Sbjct  1084  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1143

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
             ANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1144  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1203

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1204  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1253

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1254  GGFNPGNTNTGYLNIGN  1270


 Score =  674 bits (1738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/646 (64%), Positives = 485/646 (76%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1936  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1995

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1996  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  2055

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  2056  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  2115

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  2116  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2174

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2175  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2234

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2235  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2294

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2295  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2354

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2355  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2414

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2415  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2464

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  2465  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2524

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2525  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2570


 Score =  630 bits (1625),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1541  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1600

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1601  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1660

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1661  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1710

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1711  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1770

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1771  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1824

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1825  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1874

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1875  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1934

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1935  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1994

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1995  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  2044

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  2045  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  2094

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  2095  TGSFNTGGFNAGNTNTGHFNTGN  2117


 Score =  611 bits (1576),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 415/737 (57%), Positives = 479/737 (65%), Gaps = 108/737 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2339  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2396

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2397  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2456

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2457  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2516

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  2517  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  2576

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  2577  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  2635

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  2636  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  2685

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNF-----------GGG  544
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNF           G G
Sbjct  2686  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFAAGNMSGSGNFGAG  2745

Query  545   ASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG-------  597
              SGF+N      G SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG       
Sbjct  2746  NSGFFNAGGL--GNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGAN  2803

Query  598   ---LLHHSVGTMTLNFGLAN----------------------------------------  614
                L   + G +TLNFG+AN                                        
Sbjct  2804  LAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVN  2863

Query  615   VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN  674
             +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFAN
Sbjct  2864  IGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFAN  2923

Query  675   TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGI  734
             TG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI
Sbjct  2924  TGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGI  2983

Query  735   GNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGG  794
              N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG 
Sbjct  2984  FNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGY  3043

Query  795   FNAGNYNTGYFNTGDLQ  811
              N G+YNTG  NTGD+ 
Sbjct  3044  LNTGDYNTGVANTGDVD  3060


 Score =  266 bits (679),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2857  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2916

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2917  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2976

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2977  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  3036

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  3037  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  3094


 Score = 85.5 bits (210),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  3075  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  3122

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  3123  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3165


 Score = 72.8 bits (177),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 63/131 (49%), Positives = 77/131 (59%), Gaps = 3/131 (2%)

Query  696  GSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIG  755
            GS  +GF +L  GS N+GL N G  NIG  N+GS N G GN G+ N GIG +G G FG  
Sbjct  226  GSYNLGFANL--GSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNG-FGSF  282

Query  756  NAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHG  815
            N+GS N GLFNSG  N G  N G+ N G  N+G+ N G  N G+ NTG+FNTGD+     
Sbjct  283  NSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGF  342

Query  816  EHRQYQHRRFH  826
                Y    F+
Sbjct  343  NPGSYNTGNFN  353


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2992  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  3051

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  3052  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  3111

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  3112  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3168

Query  356   NT  357
              T
Sbjct  3169  GT  3170


>gi|121636220|ref|YP_976443.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224988693|ref|YP_002643380.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|121491867|emb|CAL70330.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224771806|dbj|BAH24612.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341600236|emb|CCC62906.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=1975

 Score = 1328 bits (3437),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 799/809 (99%), Positives = 799/809 (99%), Gaps = 10/809 (1%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTG          NFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTG----------NFNTGNY  350

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  351  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  410

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  411  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  470

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  471  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  530

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  531  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  590

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  591  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  650

Query  661  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  720
            GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG
Sbjct  651  GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDG  710

Query  721  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY
Sbjct  711  NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  770

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  771  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  799


 Score =  708 bits (1828),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  1082  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  1141

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  1142  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1201

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1202  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1261

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1262  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1319

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1320  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1379

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1380  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1436

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1437  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1496

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1497  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1556

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1557  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1616

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1617  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1676

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1677  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1736

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1737  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1769


 Score =  695 bits (1794),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/677 (63%), Positives = 488/677 (73%), Gaps = 76/677 (11%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  598   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  657

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  658   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  717

Query  308   GTGNFGIGNSGT----------GNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GT          GNFG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  718   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  777

Query  358   GNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
             G+ NTG FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   
Sbjct  778   GSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWRGDNQGLIDLA  837

Query  418   IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVEL-----P  472
             I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++GPV++     P
Sbjct  838   IGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVP  896

Query  473   QSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
                +T PT  + VGGPTT I+   T  V  ++IP+I IPA PGFGNST   SSGFFN+GA
Sbjct  897   VIRITGPTPVVMVGGPTTAINIGATVGVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGA  956

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TP
Sbjct  957   GSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTP  1016

Query  593   AFNS----------GLLHHSVGTMTLNFGLAN--------------------VGGNNVGG  622
             A NS          GLL    GT  +N GLAN                    +G NNVG 
Sbjct  1017  AVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGI  1076

Query  623   ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GF  672
              N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GF
Sbjct  1077  GNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGF  1136

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
             ANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNF
Sbjct  1137  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNF  1196

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                       GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NT
Sbjct  1197  ----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNT  1246

Query  793   GGFNAGNYNTGYFNTGD  809
             GGFN GN NTGY N G+
Sbjct  1247  GGFNPGNTNTGYLNIGN  1263


 Score =  449 bits (1155),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 277/464 (60%), Positives = 334/464 (72%), Gaps = 38/464 (8%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1534  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1593

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1594  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1653

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1654  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1703

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1704  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1763

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1764  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1817

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1818  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1867

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1868  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1927

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNL  650
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNL
Sbjct  1928  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNL  1971


 Score =  189 bits (481),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 126/231 (55%), Positives = 145/231 (63%), Gaps = 29/231 (12%)

Query  635  LGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGL  694
            LG YN+GF NLG DNLG A+ G +NIGFANTGSNN+GF NTG          SNN+GIGL
Sbjct  225  LGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTG----------SNNVGIGL  274

Query  695  TGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGI  754
            TG+GQIGFGS NSGSHNIGLFNSG GN+GLFNSG+GNFGIGN+GTGN+G+GN+G+ N G 
Sbjct  275  TGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGW  334

Query  755  GNAGSTNTGLFNSGDLNTGSLNPGSYNTG-----S-----VNTGSVNTGGFNAGNYNTGY  804
             N G  NTG FN+G+ NTGS N G+YNTG            NTG+VNTG F AGNY+ G 
Sbjct  335  FNTGDVNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGV  394

Query  805  FNTGDLQHRHGEHRQY---------QHRRFHLRQPQQRPSVAGRQPGSDRP  846
               GD Q   G              Q     + Q    P      PG   P
Sbjct  395  LWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLP  445


 Score = 57.0 bits (136),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 29/45 (65%), Positives = 35/45 (78%), Gaps = 0/45 (0%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL  242
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNL L
Sbjct  1929  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLAL  1973


 Score = 41.6 bits (96),  Expect = 0.73, Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 32/46 (70%), Gaps = 0/46 (0%)

Query  227   SYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGI  272
             + NLG ANLGS+N G  N G  ++G AN G+ N+GFGN G +N+ +
Sbjct  1928  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLAL  1973


>gi|289568217|ref|ZP_06448444.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289541970|gb|EFD45619.1| PPE family protein [Mycobacterium tuberculosis T17]
Length=704

 Score = 1122 bits (2902),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 676/677 (99%), Positives = 676/677 (99%), Gaps = 0/677 (0%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP
Sbjct  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL
Sbjct  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE
Sbjct  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240
            RLTSAAAAAAGPPSAAGFNLGLANV ANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL
Sbjct  181  RLTSAAAAAAGPPSAAGFNLGLANVAANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNL  240

Query  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300
            GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG
Sbjct  241  GLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSG  300

Query  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360
            NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY
Sbjct  301  NVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNY  360

Query  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420
            NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL
Sbjct  361  NTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIAL  420

Query  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
            EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT
Sbjct  421  EIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN
Sbjct  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
            FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH
Sbjct  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600

Query  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660
            HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI
Sbjct  601  HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNI  660

Query  661  GFANTGSNNLGFANTGD  677
            GFANTGSNNLGFANTGD
Sbjct  661  GFANTGSNNLGFANTGD  677


 Score =  217 bits (553),  Expect = 7e-54, Method: Compositional matrix adjust.
 Identities = 125/175 (72%), Positives = 139/175 (80%), Gaps = 20/175 (11%)

Query  635  LGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGL  694
            LG YN+GF NLG DNLG A+ G +NIGFANTGSNN+GF NT          GSNN+GIGL
Sbjct  225  LGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNT----------GSNNVGIGL  274

Query  695  TGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGI  754
            TG+GQIGFGS NSGSHNIGLFNSG GN+GLFNSG+GNFGIGN+GT          GNFG+
Sbjct  275  TGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGT----------GNFGL  324

Query  755  GNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            GN GSTNTG FN+GD+NTG  NPGSYNTG+ NTG+ NTG FNAGNYNTGYFNTGD
Sbjct  325  GNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGD  379


 Score = 53.5 bits (127),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 62/153 (41%), Positives = 77/153 (51%), Gaps = 5/153 (3%)

Query  661  GFANTGSNNL-GFANTGDNNIGFANIGSNNIGI-GLTGSGQIGFGSLNSGSHNIGLFNSG  718
            GF N G+    GF N G    GF N+ S   G+ G    G +G G  N G+   GL+N+ 
Sbjct  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585

Query  719  DGNIGL--FNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776
              N+    FNSG  +  +G   T N+G+ N G  N G  NAG  N GL N GD N G  N
Sbjct  586  TSNLATPAFNSGLLHHSVGTM-TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGN  644

Query  777  PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
             G  N G  + GS N G  N G+ N G+ NTGD
Sbjct  645  LGGDNLGFAHAGSYNIGFANTGSNNLGFANTGD  677


 Score = 47.0 bits (110),  Expect = 0.017, Method: Compositional matrix adjust.
 Identities = 50/138 (37%), Positives = 67/138 (49%), Gaps = 28/138 (20%)

Query  199  NLGLANVGANNVGNGNVGVFNVGFGNLGS--YNLGFAN----LGSDNLGLANLGGHNIGF  252
            N+G    G  NVGN   G++N    NL +  +N G  +      + N GLAN+GG+N+G 
Sbjct  563  NVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGG  622

Query  253  ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNF  312
            AN G  NVG  N G  N+G G  G   +GF   ++GS+NIG  N+GS N+G         
Sbjct  623  ANAGIFNVGLANLGDYNIGFGNLGGDNLGFA--HAGSYNIGFANTGSNNLG---------  671

Query  313  GIGNSGTGNFGLGNTGST  330
                         NTG T
Sbjct  672  -----------FANTGDT  678


>gi|289552558|ref|ZP_06441768.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289437190|gb|EFD19683.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
Length=3031

 Score = 1106 bits (2860),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 644/654 (99%), Positives = 644/654 (99%), Gaps = 10/654 (1%)

Query  166  MPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNL  225
            MPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNL
Sbjct  1    MPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNL  60

Query  226  GSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSF  285
            GSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSF
Sbjct  61   GSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSF  120

Query  286  NSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGF  345
            NSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGF
Sbjct  121  NSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGF  180

Query  346  NPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVL  405
            NPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVL
Sbjct  181  NPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVL  240

Query  406  WRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVY  465
            WRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVY
Sbjct  241  WRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVY  300

Query  466  YGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
            YGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS
Sbjct  301  YGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  360

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS
Sbjct  361  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  420

Query  586  TSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNL  645
            TSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNL
Sbjct  421  TSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNL  480

Query  646  GGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSL  705
            GGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSL
Sbjct  481  GGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSL  540

Query  706  NSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLF  765
            NSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLF
Sbjct  541  NSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLF  600

Query  766  NSGDLNTGSLNPGSY----------NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NSGDLNTGSLNPGSY          NTGSVNTGSVNTGGFNAGNYNTGYFNTGD
Sbjct  601  NSGDLNTGSLNPGSYNTGSVNTGSVNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  654


 Score =  704 bits (1818),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  937   FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  996

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  997   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  1056

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  1057  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  1116

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  1117  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  1174

Query  438   QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
               +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  1175  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  1234

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  1235  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  1291

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
             ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  1292  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  1351

Query  602   SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
             S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  1352  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  1411

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  1412  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  1471

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  1472  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  1531

Query  751   ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                      N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  1532  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  1591

Query  802   TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
              G+  +G+ Q   G H         L      P
Sbjct  1592  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  1624


 Score =  687 bits (1772),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/687 (63%), Positives = 490/687 (72%), Gaps = 86/687 (12%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N GLANVG NNVG  N G+FNVG  NLG YN+GF NLG DNLG A+ G +NIGFANTGS
Sbjct  443   LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  502

Query  258   NNVGFGNTG----------SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NN+GF NTG          SNN+GIGLTG+GQIGFGS NSGSHNIGLFNSG GN+GLFNS
Sbjct  503   NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  562

Query  308   GTGNFGIGNSGTGN----------FGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNT  357
             G+GNFGIGN+GTGN          FG+GN GSTNTG FN+GD+NTG  NPGSYNTG+ NT
Sbjct  563   GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  622

Query  358   GNYNTGS----------FNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWR  407
             G+ NTGS          FNAGNYNTGYFNTGDYNTG+ANTGN+NTGAFI+GN+SNG+LWR
Sbjct  623   GSVNTGSVNTGSVNTGGFNAGNYNTGYFNTGDYNTGMANTGNINTGAFISGNHSNGLLWR  682

Query  408   GDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYG  467
             GD QGLI   I ++IP IPI +   ++PIH  +    + +   G+ LP  + V  V+++G
Sbjct  683   GDNQGLIDLAIGVDIPEIPIVSVDVNIPIHIPITASFTDIVYSGLDLPPNTAVT-VIFFG  741

Query  468   PVEL-----PQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTS  522
             PV++     P   +T PT  + VGGPTT I+   T +V  ++IP+I IPA PGFGNST  
Sbjct  742   PVDIDPFTVPVIRITGPTPVVMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGG  801

Query  523   PSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLY  582
              SSGFFN+GAG+ASGFGNFGG ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+Y
Sbjct  802   LSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIY  861

Query  583   NTSTSNLATPAFNS----------GLLHHSVGTMTLNFGLAN------------------  614
             N  TS+L+TPA NS          GLL    GT  +N GLAN                  
Sbjct  862   NVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGG  921

Query  615   --VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL--  670
               +G NNVG  N GIF+VGLANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL  
Sbjct  922   ATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGF  981

Query  671   --------GFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNI  722
                     GFANTG NN+GF N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NI
Sbjct  982   ANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNI  1041

Query  723   GLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNT  782
             G FNSGSGNF          GI NSG+ N GIGN G+TNTGLFNSGD+NTG+ NPGS+NT
Sbjct  1042  GFFNSGSGNF----------GIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNT  1091

Query  783   GSVNTGSVNTGGFNAGNYNTGYFNTGD  809
             GS NTGS NTGGFN GN NTGY N G+
Sbjct  1092  GSFNTGSFNTGGFNPGNTNTGYLNIGN  1118


 Score =  670 bits (1728),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1784  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1843

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1844  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1903

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1904  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1963

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1964  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  2022

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  2023  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  2082

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  2083  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  2142

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  2143  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  2202

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  2203  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  2262

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  2263  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  2312

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  2313  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  2372

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  2373  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  2423


 Score =  628 bits (1620),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  1389  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  1448

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  1449  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  1508

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  1509  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  1558

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  1559  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  1618

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  1619  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1672

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1673  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1722

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1723  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1782

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1783  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1842

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1843  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1892

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1893  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1942

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1943  TGSFNTGGFNAGNTNTGHFNTGN  1965


 Score =  609 bits (1570),  Expect = 8e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  2187  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  2244

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  2245  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  2304

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  2305  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  2364

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  2365  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  2424

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  2425  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  2483

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  2484  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  2533

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  2534  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  2593

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  2594  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  2653

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  2654  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2713

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2714  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2773

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2774  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2833

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2834  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  2893

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  2894  TGYLNTGDYNTGVANTGDVD  2913


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2710  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2769

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2770  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2829

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2830  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2889

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2890  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2947


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2928  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2975

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2976  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  3018


 Score = 73.6 bits (179),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 66/153 (44%), Positives = 81/153 (53%), Gaps = 24/153 (15%)

Query  676  GDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIG  735
            G  N+GFAN+GS+N+G+             N G HNIG  N+G  N+G  N+GS N GIG
Sbjct  61   GSYNLGFANLGSDNLGL------------ANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  108

Query  736  NAGTGNWGIG--NSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTG  793
              G G  G G  NSG+ N G+ N+GS N GLFNSG  N G  N G+ N G  NTGS NTG
Sbjct  109  LTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTG  168

Query  794  GFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
                      +FNTGD+         Y    F+
Sbjct  169  ----------WFNTGDVNTGGFNPGSYNTGNFN  191


 Score = 53.5 bits (127),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2845  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2904

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2905  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2964

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2965  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  3021

Query  356   NT  357
              T
Sbjct  3022  GT  3023


>gi|183981653|ref|YP_001849944.1| PPE family protein [Mycobacterium marinum M]
 gi|183174979|gb|ACC40089.1| PPE family protein [Mycobacterium marinum M]
Length=2754

 Score =  743 bits (1917),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/899 (53%), Positives = 586/899 (66%), Gaps = 74/899 (8%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M+F V  PE+NS R++ GAGSGP+LAAA AW GLA EL  AA+ F +VTSGL   +WRGP
Sbjct  1    MNFAVLPPEINSARLFSGAGSGPVLAAATAWTGLAAELRSAAAAFLAVTSGLTGNSWRGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AA  M+   A Y+GWL ++ A AEQAA QA+ A   FEAARA TV P +VAANRA LVSL
Sbjct  61   AAAVMSDVAASYVGWLSASGAHAEQAAEQAKTAAQVFEAARAVTVQPGLVAANRAQLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFT-----------  169
            V SNL G NAPAIA  EA YE+MWAQDV AM+ YHAGAS+  +AL P +           
Sbjct  121  VGSNLFGQNAPAIATAEAQYEQMWAQDVVAMLDYHAGASSVAAALTPLSWPTQTLAGLAA  180

Query  170  -----QQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGN  224
                   + +    +    +A     G  +   FNLGL N+G+ NVG+GN+G  NVG GN
Sbjct  181  PAAALGSVARSISFNVGFANAGQGNVGAANIGDFNLGLGNIGSGNVGSGNIGGINVGSGN  240

Query  225  LGSYNLGFANLGSDNLGLANLGG----------HNIGFANTGSNNVGFGNTGSNNVGIGL  274
             GSYN+G  NLG  N+GL NLG           HN+G AN G NN GF NTGSNN+GIGL
Sbjct  241  RGSYNIGPGNLGDYNIGLGNLGDSSVGFGNAGDHNVGVANAGFNNFGFANTGSNNIGIGL  300

Query  275  TGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGW  334
            +G+GQ+G G+ NSG+ NIGLFNSG+ N+GLFNSGTGNFGIGNSG  N G+GN G+TNTG 
Sbjct  301  SGDGQVGIGALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGL  360

Query  335  FNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGA  394
             N G VNTG  N G+YN+G FN G+ NTGSFN+G+YNTGY N G+YNTG+AN+G+VNTGA
Sbjct  361  LNAGLVNTGVGNAGNYNSGGFNAGHTNTGSFNSGDYNTGYLNPGNYNTGLANSGDVNTGA  420

Query  395  FIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINA-QLFSMPI-HQVMVMPGSVMTIPGM  452
            FI+GNYSNG  WRGD+QG  G   ++ IPAIPIN  + +S+ I     + P S+ +    
Sbjct  421  FISGNYSNGAFWRGDHQG-TGISYSVTIPAIPININETYSLDIPFTEDIGPRSIASFVIP  479

Query  453  RLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPA  512
            R   T I   ++Y GP+ +PQ  +T P ++  +G  T  +  + TG +G V +P+I IPA
Sbjct  480  RQSVTVIGIDLLYLGPITIPQINITGPVLSFEIGPATLRL--HATGEIGPVEVPIIDIPA  537

Query  513  APGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVA  572
             PGFGN+TT+PSSGFFN G G+ SGFGNF    SGF N+ S +SG+    N+GAL SG+A
Sbjct  538  TPGFGNTTTNPSSGFFNTGDGSVSGFGNFAARTSGFLNVGSGSSGVQ---NLGALQSGLA  594

Query  573  NVGNTISGLYNTSTSNLATPAFNSGL----------LHHSVGTMTLNFGLANVGGNNVGG  622
            N+G+T+SG +NT    L  PA  SG+             + G    N GL N+G  NVG 
Sbjct  595  NLGDTVSGAFNTG---LGVPAHVSGVGNVGSELAGFFRDAAGQAPFNLGLGNIGFGNVGS  651

Query  623  ANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGF  682
            AN G FNVG AN+GDYNIG GNLG  N+G  + G  ++G AN G  N+G AN G NN G 
Sbjct  652  ANVGSFNVGPANMGDYNIGPGNLGNYNVGLGNLGDSSVGLANAGDLNVGVANAGSNNFGL  711

Query  683  ANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNW  742
            AN GSNNIGIGL+G GQ+GFG+LNSG+ NIGLFNSG  NIGLFNSG+GNFGIGN+G  N 
Sbjct  712  ANTGSNNIGIGLSGDGQVGFGALNSGTGNIGLFNSGADNIGLFNSGTGNFGIGNSGDYNT  771

Query  743  GIGNSGAGNFGI--------------------GNAGSTNTGLFNSGDLNTGSLNPGSYNT  782
            GIGN+GA N G+                     NAG TNTG FNSGD NTG LNPG+YNT
Sbjct  772  GIGNAGATNTGLLNAGLVNTGVSNAGNYNSGGFNAGHTNTGSFNSGDYNTGYLNPGNYNT  831

Query  783  GSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQP  841
            G VN+G VNTG F +G+Y+ G F         G+H+      + +  P+    + G  P
Sbjct  832  GLVNSGDVNTGAFISGDYSNGAF-------WRGDHQGLADISYGITIPEIPAHIEGTIP  883


 Score =  583 bits (1503),  Expect = 5e-164, Method: Compositional matrix adjust.
 Identities = 381/703 (55%), Positives = 468/703 (67%), Gaps = 53/703 (7%)

Query  173   KKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGF  232
              +LAG     T  A    G  +    N+G  N+G  NVG+GN+G +N+G  NLG YN+G 
Sbjct  1047  SELAGFFRDATGHARFNLGLGNIGSGNVGSGNIGGANVGSGNIGDYNIGPANLGDYNIGL  1106

Query  233   ANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNI  292
              NLG  ++GLAN G HN+G AN G NN GF NTG+NN+GIGL+G+GQ+GFG+ NSG+ NI
Sbjct  1107  GNLGDSSIGLANAGDHNLGVANAGFNNFGFANTGNNNIGIGLSGDGQVGFGALNSGTGNI  1166

Query  293   GLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNT  352
             GLFNSG+ N+GLFNSGTGNFGIGNSG  N G+GN G+TNTG  N G VNTG  N G+YN+
Sbjct  1167  GLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNS  1226

Query  353   GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQG  412
             G FNTG+ NTGSFN+G+YNTGY N G+YNTG+AN+G+VNTGAFI+G+YSNG  WRGD+QG
Sbjct  1227  GGFNTGSTNTGSFNSGDYNTGYLNPGNYNTGLANSGDVNTGAFISGDYSNGAFWRGDHQG  1286

Query  413   LIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTI--PGMRLPFTSIVPFVVY-----  465
             L+G   A+ IP  P +A++ S+PI   + + G++  I  P +R+P     P  VY     
Sbjct  1287  LVGFSYAINIPETPGHAEI-SIPID--IPINGTIGDINTPRVRIP---EFPLNVYVFTPI  1340

Query  466   ----YGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTT  521
                  GP+ LP   +T PT+T  +GGPTT+ID  + G +G   I +I IPAAPGFGNSTT
Sbjct  1341  HVGDVGPIVLPPIRITGPTLTGNIGGPTTSIDIGIGGTLGPAKITIIDIPAAPGFGNSTT  1400

Query  522   SPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGL  581
             SPSSGFFN+G G+ SGFGNFG   SG  N  S  SG     NVGAL SG+AN+G+T+SG 
Sbjct  1401  SPSSGFFNSGDGSVSGFGNFGDHTSGLVNFGSGNSGAQ---NVGALQSGLANLGDTVSGA  1457

Query  582   YNTSTSNLATPAFNSGL----------LHHSVGTMTLNFGLANVGGNNVGGANAGIFNVG  631
             +NT    L  PA  SG+             + G    N GL N+G  NVG ANAG FNVG
Sbjct  1458  FNTG---LGVPAHVSGVGNVGSELAGFFRDATGHAPFNLGLGNIGFGNVGSANAGNFNVG  1514

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
              AN+GDYNIG GNLG  N+G  + G  +IG AN G +NLG AN G NN GFAN G+NNIG
Sbjct  1515  SANIGDYNIGPGNLGDYNIGLGNLGDSSIGLANAGDHNLGVANAGFNNFGFANTGNNNIG  1574

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
             IGL+G GQ+G G+LNSG+ NIGLFNSG  NIGLFNSG+GNFGIGN+G  N GIGN+GA  
Sbjct  1575  IGLSGDGQVGIGALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATN  1634

Query  751   ---------NFGIGNAGS----------TNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
                      N G+GNAG+          TNTG FNSGD NTG LNPG+YNTG VN+G VN
Sbjct  1635  TGLLNAGLVNTGVGNAGNYNSGGLNAGHTNTGSFNSGDYNTGYLNPGNYNTGMVNSGDVN  1694

Query  792   TGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             TG F +G+Y+ G F  GD Q   G    +       +   Q P
Sbjct  1695  TGAFISGDYSNGAFWRGDHQGLVGFSYGFTIPALPAQLEAQIP  1737


 Score =  565 bits (1455),  Expect = 2e-158, Method: Compositional matrix adjust.
 Identities = 367/664 (56%), Positives = 448/664 (68%), Gaps = 35/664 (5%)

Query  173   KKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGF  232
              +LAG     T  A    G  +    N+G AN G  NVG+ N+G +N+G GNLG YN+G 
Sbjct  1476  SELAGFFRDATGHAPFNLGLGNIGFGNVGSANAGNFNVGSANIGDYNIGPGNLGDYNIGL  1535

Query  233   ANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNI  292
              NLG  ++GLAN G HN+G AN G NN GF NTG+NN+GIGL+G+GQ+G G+ NSG+ NI
Sbjct  1536  GNLGDSSIGLANAGDHNLGVANAGFNNFGFANTGNNNIGIGLSGDGQVGIGALNSGTGNI  1595

Query  293   GLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNT  352
             GLFNSG+ N+GLFNSGTGNFGIGNSG  N G+GN G+TNTG  N G VNTG  N G+YN+
Sbjct  1596  GLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNS  1655

Query  353   GNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQG  412
             G  N G+ NTGSFN+G+YNTGY N G+YNTG+ N+G+VNTGAFI+G+YSNG  WRGD+QG
Sbjct  1656  GGLNAGHTNTGSFNSGDYNTGYLNPGNYNTGMVNSGDVNTGAFISGDYSNGAFWRGDHQG  1715

Query  413   LIGADIALEIPAIPINAQLFS-MPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVY------  465
             L+G      IPA+P  AQL + +P++          TI     P      F +       
Sbjct  1716  LVGFSYGFTIPALP--AQLEAQIPVNIPATATAGDTTIHSATFPAIHFDTFGLLPQSNGT  1773

Query  466   YGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
             +GPV LP  TL+ PT ++ +GGP T +     G+ G V+   I IPAAPGFGN+T +PSS
Sbjct  1774  FGPVTLPDITLSGPTFSLLMGGPDTVVGIKAGGVAGPVTFSFIDIPAAPGFGNTTATPSS  1833

Query  526   GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
             GFFN+GAG+ASGFGN G   SG  NLA    G SG+ NVGAL SG+AN+GNT+SG+YNT 
Sbjct  1834  GFFNSGAGSASGFGNSGADNSGLLNLA---FGSSGYQNVGALQSGIANLGNTMSGVYNTG  1890

Query  586   TSNLATPAFNS----------GLLHHSVGTMTLNFGLA----------NVGGNNVGGANA  625
                LA PA  S          GLL  + G + +N G A          NVG +NVG  N 
Sbjct  1891  ---LAVPAHVSGIGNIGHNLAGLLRGTAGQVPVNVGFANNGAGNVGFGNVGFSNVGSGNI  1947

Query  626   GIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANI  685
             G FNVG  N+GDYNIG GNLG  N+G  + G  +IGF N G +N+G AN G NN GFAN 
Sbjct  1948  GSFNVGSGNIGDYNIGPGNLGDYNIGLGNLGDSSIGFGNAGDHNVGVANAGFNNFGFANT  2007

Query  686   GSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIG  745
             GSNNIGIGL G GQ+GFG+LNSG+ NIGLFNSG  NIGLFNSG+GNFGIGN+G  N GIG
Sbjct  2008  GSNNIGIGLNGDGQVGFGALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIG  2067

Query  746   NSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYF  805
             N+GA N G+ NAG  NTG+ N+G+ N+G  N GS NTGS N G  NTGG N G+YNTGY 
Sbjct  2068  NAGATNTGLLNAGLVNTGVGNAGNYNSGGFNTGSTNTGSFNPGDYNTGGLNQGDYNTGYL  2127

Query  806   NTGD  809
             N+GD
Sbjct  2128  NSGD  2131


 Score =  563 bits (1451),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 368/715 (52%), Positives = 458/715 (65%), Gaps = 43/715 (6%)

Query  196   AGFNLGLANVGANNVGNGNVGVFNVGF----------GNLGSYNLGFANLGSDNLGLANL  245
             A FNLGL N+G  NVG+ NVG FNVG           GNLG+YN+G  NLG  ++GLAN 
Sbjct  635   APFNLGLGNIGFGNVGSANVGSFNVGPANMGDYNIGPGNLGNYNVGLGNLGDSSVGLANA  694

Query  246   GGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLF  305
             G  N+G AN GSNN G  NTGSNN+GIGL+G+GQ+GFG+ NSG+ NIGLFNSG+ N+GLF
Sbjct  695   GDLNVGVANAGSNNFGLANTGSNNIGIGLSGDGQVGFGALNSGTGNIGLFNSGADNIGLF  754

Query  306   NSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSF  365
             NSGTGNFGIGNSG  N G+GN G+TNTG  N G VNTG  N G+YN+G FN G+ NTGSF
Sbjct  755   NSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVSNAGNYNSGGFNAGHTNTGSF  814

Query  366   NAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAI  425
             N+G+YNTGY N G+YNTG+ N+G+VNTGAFI+G+YSNG  WRGD+QGL      + IP I
Sbjct  815   NSGDYNTGYLNPGNYNTGLVNSGDVNTGAFISGDYSNGAFWRGDHQGLADISYGITIPEI  874

Query  426   PINAQLFSMPIHQVMVMPGSVMTIPGMRLPF--TSIVPFVVYYGPVELPQSTLTLPTVTI  483
             P + +  ++P+   + M  +   I  + +P      +   +  GPV +P   +T PT+T 
Sbjct  875   PAHIE-GTIPLAVPVTMTSTNTVIHAVTIPVFDAGFLGIPIDAGPVTIPAIVITGPTLTG  933

Query  484   TVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGG  543
              +GGPT+ I+ N    VG + +  + IPAAPGFGNSTT+PSSGFFN G GT SGFGN G 
Sbjct  934   IIGGPTSAININTGQHVGPIRLSFLDIPAAPGFGNSTTNPSSGFFNLGQGTVSGFGNLGA  993

Query  544   GASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL-----  598
               SGF N+    SG+SG  NVGAL SG+AN+G+T+SG +NT    L  PA  SGL     
Sbjct  994   RTSGFLNVG---SGISGVQNVGALQSGLANLGDTVSGAFNTG---LGVPAHVSGLGNAGS  1047

Query  599   -----LHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFA  653
                     + G    N GL N+G  NVG  N G  NVG  N+GDYNIG  NLG  N+G  
Sbjct  1048  ELAGFFRDATGHARFNLGLGNIGSGNVGSGNIGGANVGSGNIGDYNIGPANLGDYNIGLG  1107

Query  654   HAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIG  713
             + G  +IG AN G +NLG AN G NN GFAN G+NNIGIGL+G GQ+GFG+LNSG+ NIG
Sbjct  1108  NLGDSSIGLANAGDHNLGVANAGFNNFGFANTGNNNIGIGLSGDGQVGFGALNSGTGNIG  1167

Query  714   LFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTG  773
             LFNSG  NIGLFNSG+GNFGIGN+G  N GIGN+GA N G+ NAG  NTG+ N+G+ N+G
Sbjct  1168  LFNSGTDNIGLFNSGTGNFGIGNSGDYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSG  1227

Query  774   SLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ-------------HRHGEHRQY  820
               N GS NTGS N+G  NTG  N GNYNTG  N+GD+                 G+H+  
Sbjct  1228  GFNTGSTNTGSFNSGDYNTGYLNPGNYNTGLANSGDVNTGAFISGDYSNGAFWRGDHQGL  1287

Query  821   QHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLH  875
                 + +  P + P  A      D P +      N    R  E+P +      +H
Sbjct  1288  VGFSYAINIP-ETPGHAEISIPIDIPINGTIGDINTPRVRIPEFPLNVYVFTPIH  1341


 Score =  514 bits (1325),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 354/687 (52%), Positives = 437/687 (64%), Gaps = 87/687 (12%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSN  258
             N+G  N+G+ NVG+GN+G +N+G GNLG YN+G  NLG  ++G  N G HN+G AN G N
Sbjct  1941  NVGSGNIGSFNVGSGNIGDYNIGPGNLGDYNIGLGNLGDSSIGFGNAGDHNVGVANAGFN  2000

Query  259   NVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSG  318
             N GF NTGSNN+GIGL G+GQ+GFG+ NSG+ NIGLFNSG+ N+GLFNSGTGNFGIGNSG
Sbjct  2001  NFGFANTGSNNIGIGLNGDGQVGFGALNSGTGNIGLFNSGTDNIGLFNSGTGNFGIGNSG  2060

Query  319   TGNFGLGNTGSTNTGWFNTGDVNT----------GGFNPGSYNTGNFNTGNYNTGSFNAG  368
               N G+GN G+TNTG  N G VNT          GGFN GS NTG+FN G+YNTG  N G
Sbjct  2061  DYNTGIGNAGATNTGLLNAGLVNTGVGNAGNYNSGGFNTGSTNTGSFNPGDYNTGGLNQG  2120

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             +YNTGY N+GDYNTG  N G+VNTGAFI+GNYSNG   RGDYQ LIG   ++ +   P  
Sbjct  2121  DYNTGYLNSGDYNTGFVNAGDVNTGAFISGNYSNGFFARGDYQNLIGWSYSITVSEFPAY  2180

Query  429   AQL-------FSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYY--GPVELPQSTLTLP  479
               L       F+  I  + +   ++ ++P   L + +  P  ++Y  GP+ + ++T T P
Sbjct  2181  GTLDIPVYIPFTGAIGPITIQEFTIPSLPLDALVYINGTPIPIFYDFGPITVDETT-TDP  2239

Query  480   TVTITVG--------GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAG  531
                  V         GP T          G   IPL   P  PGF NSTTSPSSGFFN+G
Sbjct  2240  IALNFVWDQLYHYEVGPRT---------FGPYEIPLFSFP-GPGFANSTTSPSSGFFNSG  2289

Query  532   AGTASGFGNFGGGA-SGFWNLASATSGL----------SGFGNVGALGSGVANVGNTISG  580
              G  SGF N G G+ SG  NL +  SG           SGF N GAL SG+ANVGNTISG
Sbjct  2290  TGPTSGFFNSGAGSLSGLINLGANNSGFANTGIGGLGNSGFINDGALQSGMANVGNTISG  2349

Query  581   LYNTSTSNLATPAFNSGLLH---------------HSVGTMTL---NFGLANVGGNNVGG  622
             +YN++T +    A  SG+ +               H++G   L   N G AN+G  N+GG
Sbjct  2350  IYNSTTLDPTAVANVSGIANTGVDLAGVFRGASRIHNLGFANLGIANLGSANIGDLNLGG  2409

Query  623   ANAG--------------------IFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGF  662
             AN G                      N+G  NLGD+NIG GNLG  N+G  + G  N+GF
Sbjct  2410  ANFGSANIGSGNIGFGNVGGGNVGSLNLGFGNLGDHNIGPGNLGDYNIGLGNLGDSNVGF  2469

Query  663   ANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNI  722
              N G +N+G  N G NN GFAN GSNNIGIGL+G GQ+GFG+LNSG+ NIGLFNSG  NI
Sbjct  2470  GNAGDHNVGVGNAGFNNFGFANTGSNNIGIGLSGDGQVGFGALNSGTGNIGLFNSGTDNI  2529

Query  723   GLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNT  782
             GLFNSG+GN G+ N+GTG++GIGNSG  N GIGNAG+TNTGLFN+G +NTG  N G+YN+
Sbjct  2530  GLFNSGTGNIGLFNSGTGSFGIGNSGNYNTGIGNAGATNTGLFNTGLVNTGVGNAGNYNS  2589

Query  783   GSVNTGSVNTGGFNAGNYNTGYFNTGD  809
             G  NTGS NTG FN+G++NTGY N+GD
Sbjct  2590  GGFNTGSTNTGSFNSGDHNTGYLNSGD  2616


 Score =  239 bits (609),  Expect = 3e-60, Method: Compositional matrix adjust.
 Identities = 139/216 (65%), Positives = 170/216 (79%), Gaps = 10/216 (4%)

Query  209   NVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSN  268
             N+G GN+G  N+G GNLG YN+G  NLG  N+G  N G HN+G  N G NN GF NTGSN
Sbjct  2436  NLGFGNLGDHNIGPGNLGDYNIGLGNLGDSNVGFGNAGDHNVGVGNAGFNNFGFANTGSN  2495

Query  269   NVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNT-  327
             N+GIGL+G+GQ+GFG+ NSG+ NIGLFNSG+ N+GLFNSGTGN G+ NSGTG+FG+GN+ 
Sbjct  2496  NIGIGLSGDGQVGFGALNSGTGNIGLFNSGTDNIGLFNSGTGNIGLFNSGTGSFGIGNSG  2555

Query  328   ---------GSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTG  378
                      G+TNTG FNTG VNTG  N G+YN+G FNTG+ NTGSFN+G++NTGY N+G
Sbjct  2556  NYNTGIGNAGATNTGLFNTGLVNTGVGNAGNYNSGGFNTGSTNTGSFNSGDHNTGYLNSG  2615

Query  379   DYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLI  414
             DYNTG+AN+G+VNTGAFI+GNYSNG    GD+QGLI
Sbjct  2616  DYNTGLANSGDVNTGAFISGNYSNGFFVDGDHQGLI  2651


 Score = 76.3 bits (186),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 52/90 (58%), Positives = 62/90 (69%), Gaps = 4/90 (4%)

Query  510   IPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASAT-SGLSGFGNVGALG  568
             I   PGF NSTT+PSSG  N+G G+ SG GN+G G SGF N AS T +G SG  NVGAL 
Sbjct  2651  IDGTPGFFNSTTNPSSGLLNSGEGSESGVGNYGVGNSGFLNFASVTGAGSSGLLNVGALQ  2710

Query  569   SGVANVGNTISGLYNTSTSNLATPAFNSGL  598
             SG+ N+G+TISG  NT +    TPAF SG+
Sbjct  2711  SGILNLGSTISGFGNTGS---VTPAFVSGV  2737


 Score = 71.6 bits (174),  Expect = 7e-10, Method: Compositional matrix adjust.
 Identities = 79/197 (41%), Positives = 105/197 (54%), Gaps = 24/197 (12%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             +N G+ N GA N G  N G+ N G GN G+YN G  N GS N G  N G HN G+ N+G 
Sbjct  2557  YNTGIGNAGATNTGLFNTGLVNTGVGNAGNYNSGGFNTGSTNTGSFNSGDHNTGYLNSGD  2616

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGF--------------GSFNSGSH-NIGLFNSGSGNV  302
              N G  N+G  N G  ++GN   GF              G FNS ++ + GL NSG G+ 
Sbjct  2617  YNTGLANSGDVNTGAFISGNYSNGFFVDGDHQGLIDGTPGFFNSTTNPSSGLLNSGEGS-  2675

Query  303   GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGN---  359
                 SG GN+G+GNSG  NF    TG+ ++G  N G + +G  N GS  +G  NTG+   
Sbjct  2676  ---ESGVGNYGVGNSGFLNF-ASVTGAGSSGLLNVGALQSGILNLGSTISGFGNTGSVTP  2731

Query  360   -YNTGSFNAGNYNTGYF  375
              + +G  NAG   +G+F
Sbjct  2732  AFVSGVANAGTRLSGFF  2748


 Score = 58.2 bits (139),  Expect = 8e-06, Method: Compositional matrix adjust.
 Identities = 73/185 (40%), Positives = 87/185 (48%), Gaps = 22/185 (11%)

Query  641   GFGNLGGDN-----LGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFA---------NIG  686
             GFGN G DN     L F  +G  N+G   +G  NLG   +G  N G A         NIG
Sbjct  1845  GFGNSGADNSGLLNLAFGSSGYQNVGALQSGIANLGNTMSGVYNTGLAVPAHVSGIGNIG  1904

Query  687   SNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGN  746
              N  G+    +GQ+          N+G  N+G GN+G  N G  N G GN G+ N G GN
Sbjct  1905  HNLAGLLRGTAGQV--------PVNVGFANNGAGNVGFGNVGFSNVGSGNIGSFNVGSGN  1956

Query  747   SGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFN  806
              G  N G GN G  N GL N GD + G  N G +N G  N G  N G  N G+ N G   
Sbjct  1957  IGDYNIGPGNLGDYNIGLGNLGDSSIGFGNAGDHNVGVANAGFNNFGFANTGSNNIGIGL  2016

Query  807   TGDLQ  811
              GD Q
Sbjct  2017  NGDGQ  2021


>gi|289445844|ref|ZP_06435588.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289418802|gb|EFD16003.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=1003

 Score =  708 bits (1827),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  110  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  169

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  170  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  229

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  230  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  289

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  290  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  347

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  348  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  407

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  408  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  464

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  465  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  524

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  525  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  584

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  585  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  644

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  645  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  704

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  705  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  764

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  765  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  797


 Score =  449 bits (1154),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 277/464 (60%), Positives = 334/464 (72%), Gaps = 38/464 (8%)

Query  199  NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
            N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  562  NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  621

Query  253  ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  622  NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  681

Query  309  TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
             GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  682  NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  731

Query  369  NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
            + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  732  DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  791

Query  429  AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
              +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  792  FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  845

Query  487  GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
            GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  846  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  895

Query  547  GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
            GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  896  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  955

Query  607  TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNL  650
            TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNL
Sbjct  956  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNL  999


 Score =  290 bits (742),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 188/301 (63%), Positives = 209/301 (70%), Gaps = 50/301 (16%)

Query  549  WNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL----------  598
             NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NSGL          
Sbjct  1    MNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGL  60

Query  599  LHHSVGTMTLNFGLAN--------------------VGGNNVGGANAGIFNVGLANLGDY  638
            L    GT  +N GLAN                    +G NNVG  N GIF+VGLANLG Y
Sbjct  61   LRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  120

Query  639  NIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGFANIGSN  688
            NIGFGNLG DNLGF + GSYNIGF N G++NL          GFANTG NN+GF N GSN
Sbjct  121  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  180

Query  689  NIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSG  748
            N+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N GIGN+ 
Sbjct  181  NVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNT-  239

Query  749  AGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
                     G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NTGY N G
Sbjct  240  ---------GNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIG  290

Query  809  D  809
            +
Sbjct  291  N  291


 Score = 56.6 bits (135),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 29/45 (65%), Positives = 35/45 (78%), Gaps = 0/45 (0%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL  242
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNL L
Sbjct  957   LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLAL  1001


 Score = 40.8 bits (94),  Expect = 1.2, Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 32/46 (70%), Gaps = 0/46 (0%)

Query  227   SYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGI  272
             + NLG ANLGS+N G  N G  ++G AN G+ N+GFGN G +N+ +
Sbjct  956   TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLAL  1001


 Score = 40.0 bits (92),  Expect = 2.3, Method: Compositional matrix adjust.
 Identities = 60/178 (34%), Positives = 70/178 (40%), Gaps = 56/178 (31%)

Query  278  GQIGFGSFNSGSHNIG-----------------LFNSGSGNV-----GLFNSGTG-----  310
            G +  G+  SG  N+G                   NSG  N+     GL   G G     
Sbjct  12   GFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAIN  71

Query  311  -----------------------------NFGIGNSGTGNFGLGNTGSTNTGWFNTGDVN  341
                                         N GIGN+G  + GL N GS N G+ N GD N
Sbjct  72   LGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDN  131

Query  342  TGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGN  399
             G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ N G  + GN
Sbjct  132  LGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGN  189


>gi|148660070|ref|YP_001281593.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148504222|gb|ABQ72031.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=2373

 Score =  706 bits (1822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  279  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  338

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  339  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  398

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  399  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  458

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  459  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  516

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  517  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  576

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  577  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  633

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  634  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  693

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  694  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  753

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  754  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  813

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  814  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  873

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  874  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  933

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  934  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  966


 Score =  671 bits (1732),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1126  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1185

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1186  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1245

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1246  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1305

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1306  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1364

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1365  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1424

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1425  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1484

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1485  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1544

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1545  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1604

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  1605  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  1654

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  1655  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1714

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1715  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1765


 Score =  629 bits (1622),  Expect = 7e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  731   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  790

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  791   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  850

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  851   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  900

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  901   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  960

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  961   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  1014

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  1015  GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  1064

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  1065  GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1124

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1125  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1184

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1185  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1234

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1235  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1284

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1285  TGSFNTGGFNAGNTNTGHFNTGN  1307


 Score =  610 bits (1573),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1529  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1586

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  1587  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  1646

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1647  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1706

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  1707  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  1766

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  1767  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  1825

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  1826  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  1875

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  1876  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  1935

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  1936  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  1995

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  1996  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  2055

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  2056  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2115

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2116  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2175

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2176  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  2235

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  2236  TGYLNTGDYNTGVANTGDVD  2255


 Score =  448 bits (1153),  Expect = 2e-123, Method: Compositional matrix adjust.
 Identities = 278/471 (60%), Positives = 328/471 (70%), Gaps = 56/471 (11%)

Query  384  VANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMP  443
            +ANTGN+NTGAFI+GN+SNG+LWRGD QGLI   I ++IP IPI +   ++PIH  +   
Sbjct  1    MANTGNINTGAFISGNHSNGLLWRGDNQGLIDLAIGVDIPEIPIVSVDVNIPIHIPITAS  60

Query  444  GSVMTIPGMRLPFTSIVPFVVYYGPVEL-----PQSTLTLPTVTITVGGPTTTIDGNLTG  498
             + +   G+ LP  + V  V+++GPV++     P   +T PT  + VGGPTT I+   T 
Sbjct  61   FTDIVYSGLDLPPNTAVT-VIFFGPVDIDPFTVPVIRITGPTPVVMVGGPTTAINIGATV  119

Query  499  MVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGL  558
            +V  ++IP+I IPA PGFGNST   SSGFFN+GAG+ASGFGNFGG ASGF NL S TSG+
Sbjct  120  VVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGM  179

Query  559  SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHHSVGTMTL  608
            SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NS          GLL    GT  +
Sbjct  180  SGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAI  239

Query  609  NFGLAN--------------------VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGD  648
            N GLAN                    +G NNVG  N GIF+VGLANLG YNIGFGNLG D
Sbjct  240  NLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDD  299

Query  649  NLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGFANIGSNNIGIGLTGSG  698
            NLGF + GSYNIGF N G++NL          GFANTG NN+GF N GSNN+GIGLTG+G
Sbjct  300  NLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNG  359

Query  699  QIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAG  758
            QIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N GIGN+          G
Sbjct  360  QIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNT----------G  409

Query  759  STNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            +TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NTGY N G+
Sbjct  410  NTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIGN  460


 Score =  265 bits (678),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  2052  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2111

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2112  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2171

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2172  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2231

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2232  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2289


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2270  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2317

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2318  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2360


 Score = 58.9 bits (141),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 98/285 (35%), Positives = 131/285 (46%), Gaps = 29/285 (10%)

Query  128  FNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERL--TSA  185
            F  P I  T      M      A+   + GA+  V A+      +    G        S+
Sbjct  90   FTVPVIRITGPTPVVMVGGPTTAI---NIGATVVVDAINIPIIHIPATPGFGNSTGGLSS  146

Query  186  AAAAAGPPSAAGF-NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLAN  244
                +G  SA+GF N G A  G  N+ +   G+   GF N+G+   G AN+G+   G+ N
Sbjct  147  GFFNSGAGSASGFGNFGGAASGFMNLVSTTSGM--SGFLNVGALGSGVANVGNTISGIYN  204

Query  245  LGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGL  304
            +G  ++   +T + N G  N G+N  G+   G G        + + N+GL N G+ NVG 
Sbjct  205  VGTSDL---STPAVNSGLANIGTNIAGLLRDGAG--------TAAINLGLANHGNLNVGF  253

Query  305  FNSGTGNFGIGNSGTGNFGLGNT----------GSTNTGWFNTGDVNTGGFNPGSYNTGN  354
             + G  NFG    G  N G+GNT          GS N G+ N GD N G  N GSYN G 
Sbjct  254  ASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGF  313

Query  355  FNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGN  399
             N GN N G  NAG  N G+ NTG  N G  NTG+ N G  + GN
Sbjct  314  GNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGN  358


 Score = 53.9 bits (128),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2187  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2246

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2247  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2306

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2307  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2363

Query  356   NT  357
              T
Sbjct  2364  GT  2365


>gi|289756369|ref|ZP_06515747.1| PPE family protein [Mycobacterium tuberculosis T85]
 gi|289711933|gb|EFD75945.1| PPE family protein [Mycobacterium tuberculosis T85]
Length=2199

 Score =  706 bits (1822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  110  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  169

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  170  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  229

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  230  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  289

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  290  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  347

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  348  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  407

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  408  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  464

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  465  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  524

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  525  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  584

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  585  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  644

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  645  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  704

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  705  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  764

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  765  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  797


 Score =  672 bits (1735),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/646 (64%), Positives = 485/646 (76%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  957   LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1016

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1017  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1076

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1077  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1136

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1137  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1195

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1196  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1255

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1256  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1315

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1316  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1375

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1376  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1435

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  1436  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  1485

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  1486  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1545

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1546  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1591


 Score =  629 bits (1623),  Expect = 7e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  562   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  621

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  622   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  681

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  682   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  731

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  732   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  791

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  792   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  845

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  846   GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  895

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  896   GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  955

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  956   TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1015

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1016  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1065

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1066  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1115

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1116  TGSFNTGGFNAGNTNTGHFNTGN  1138


 Score =  612 bits (1577),  Expect = 1e-172, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1360  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1417

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  1418  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  1477

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1478  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1537

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  1538  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  1597

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  1598  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  1656

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  1657  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  1706

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  N  + 
Sbjct  1707  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAG  1766

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  1767  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  1826

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  1827  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  1886

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  1887  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  1946

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  1947  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2006

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2007  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  2066

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  2067  TGDYNTGVANTGDVD  2081


 Score =  289 bits (739),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 188/301 (63%), Positives = 209/301 (70%), Gaps = 50/301 (16%)

Query  549  WNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL----------  598
             NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NSGL          
Sbjct  1    MNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGL  60

Query  599  LHHSVGTMTLNFGLAN--------------------VGGNNVGGANAGIFNVGLANLGDY  638
            L    GT  +N GLAN                    +G NNVG  N GIF+VGLANLG Y
Sbjct  61   LRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  120

Query  639  NIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN----------TGDNNIGFANIGSN  688
            NIGFGNLG DNLGF + GSYNIGF N G++NLGFAN          TG NN+GF N GSN
Sbjct  121  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  180

Query  689  NIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSG  748
            N+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N GIGN+ 
Sbjct  181  NVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNT-  239

Query  749  AGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
                     G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NTGY N G
Sbjct  240  ---------GNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIG  290

Query  809  D  809
            +
Sbjct  291  N  291


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  1878  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  1937

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  1938  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  1997

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  1998  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2057

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2058  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2115


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2096  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2143

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2144  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2186


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2013  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2072

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2073  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2132

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2133  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2189

Query  356   NT  357
              T
Sbjct  2190  GT  2191


 Score = 38.9 bits (89),  Expect = 4.9, Method: Compositional matrix adjust.
 Identities = 60/178 (34%), Positives = 70/178 (40%), Gaps = 56/178 (31%)

Query  278  GQIGFGSFNSGSHNIG-----------------LFNSGSGNV-----GLFNSGTG-----  310
            G +  G+  SG  N+G                   NSG  N+     GL   G G     
Sbjct  12   GFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAIN  71

Query  311  -----------------------------NFGIGNSGTGNFGLGNTGSTNTGWFNTGDVN  341
                                         N GIGN+G  + GL N GS N G+ N GD N
Sbjct  72   LGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDN  131

Query  342  TGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGN  399
             G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ N G  + GN
Sbjct  132  LGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGN  189


>gi|57116719|ref|YP_177714.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|289760413|ref|ZP_06519791.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|7478698|pir||A70524 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|38490170|emb|CAE55269.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|289707919|gb|EFD71935.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
Length=2204

 Score =  706 bits (1821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  110  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  169

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  170  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  229

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  230  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  289

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  290  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  347

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  348  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  407

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  408  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  464

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  465  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  524

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  525  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  584

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  585  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  644

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  645  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  704

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  705  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  764

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  765  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  797


 Score =  671 bits (1730),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  957   LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1016

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1017  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1076

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1077  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1136

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1137  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1195

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1196  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1255

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1256  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1315

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1316  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1375

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1376  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1435

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  1436  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  1485

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  1486  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1545

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1546  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1596


 Score =  629 bits (1622),  Expect = 7e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  562   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  621

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  622   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  681

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  682   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  731

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  732   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  791

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  792   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  845

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  846   GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  895

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  896   GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  955

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  956   TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1015

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1016  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1065

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1066  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1115

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1116  TGSFNTGGFNAGNTNTGHFNTGN  1138


 Score =  610 bits (1572),  Expect = 6e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1360  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1417

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  1418  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  1477

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1478  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1537

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  1538  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  1597

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  1598  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  1656

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  1657  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  1706

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  1707  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  1766

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  1767  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  1826

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  1827  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  1886

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  1887  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  1946

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  1947  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2006

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2007  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  2066

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  2067  TGYLNTGDYNTGVANTGDVD  2086


 Score =  289 bits (739),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 188/301 (63%), Positives = 209/301 (70%), Gaps = 50/301 (16%)

Query  549  WNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL----------  598
             NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NSGL          
Sbjct  1    MNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGL  60

Query  599  LHHSVGTMTLNFGLAN--------------------VGGNNVGGANAGIFNVGLANLGDY  638
            L    GT  +N GLAN                    +G NNVG  N GIF+VGLANLG Y
Sbjct  61   LRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  120

Query  639  NIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGFANIGSN  688
            NIGFGNLG DNLGF + GSYNIGF N G++NL          GFANTG NN+GF N GSN
Sbjct  121  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  180

Query  689  NIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSG  748
            N+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N GIGN+ 
Sbjct  181  NVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNT-  239

Query  749  AGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
                     G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NTGY N G
Sbjct  240  ---------GNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIG  290

Query  809  D  809
            +
Sbjct  291  N  291


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  1883  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  1942

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  1943  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2002

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2003  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2062

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2063  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2120


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2101  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2148

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2149  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2191


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2018  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2077

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2078  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2137

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2138  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2194

Query  356   NT  357
              T
Sbjct  2195  GT  2196


 Score = 38.9 bits (89),  Expect = 4.9, Method: Compositional matrix adjust.
 Identities = 60/178 (34%), Positives = 70/178 (40%), Gaps = 56/178 (31%)

Query  278  GQIGFGSFNSGSHNIG-----------------LFNSGSGNV-----GLFNSGTG-----  310
            G +  G+  SG  N+G                   NSG  N+     GL   G G     
Sbjct  12   GFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAIN  71

Query  311  -----------------------------NFGIGNSGTGNFGLGNTGSTNTGWFNTGDVN  341
                                         N GIGN+G  + GL N GS N G+ N GD N
Sbjct  72   LGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDN  131

Query  342  TGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGN  399
             G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ N G  + GN
Sbjct  132  LGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGN  189


>gi|308231517|ref|ZP_07663877.1| hypothetical protein TMAG_03673 [Mycobacterium tuberculosis SUMu001]
 gi|308216993|gb|EFO76392.1| hypothetical protein TMAG_03673 [Mycobacterium tuberculosis SUMu001]
Length=2271

 Score =  706 bits (1821),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  177  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  236

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  237  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  296

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  297  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  356

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  357  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  414

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  415  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  474

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  475  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  531

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  532  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  591

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  592  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  651

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  652  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  711

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  712  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  771

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  772  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  831

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  832  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  864


 Score =  669 bits (1725),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/651 (64%), Positives = 486/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1024  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1083

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1084  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1143

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1144  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1203

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1204  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1262

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1263  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1322

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1323  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1382

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVG LGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1383  NLASAASGVSGLLNVGTLGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1442

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1443  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1502

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  1503  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  1552

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  1553  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1612

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1613  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1663


 Score =  629 bits (1622),  Expect = 9e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  629   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  688

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  689   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  748

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  749   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  798

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  799   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  858

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  859   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  912

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  913   GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  962

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  963   GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1022

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1023  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1082

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1083  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1132

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1133  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1182

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1183  TGSFNTGGFNAGNTNTGHFNTGN  1205


 Score =  609 bits (1570),  Expect = 8e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1427  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1484

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  1485  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  1544

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1545  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1604

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  1605  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  1664

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  1665  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  1723

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  1724  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  1773

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  1774  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  1833

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  1834  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  1893

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  1894  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  1953

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  1954  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2013

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2014  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2073

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2074  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  2133

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  2134  TGYLNTGDYNTGVANTGDVD  2153


 Score =  364 bits (935),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 232/367 (64%), Positives = 261/367 (72%), Gaps = 50/367 (13%)

Query  483  ITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFG  542
            + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GAG+ASGFGNFG
Sbjct  2    VMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGAGSASGFGNFG  61

Query  543  GGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------  596
            G ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NS      
Sbjct  62   GAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIG  121

Query  597  ----GLLHHSVGTMTLNFGLAN--------------------VGGNNVGGANAGIFNVGL  632
                GLL    GT  +N GLAN                    +G NNVG  N GIF+VGL
Sbjct  122  TNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGL  181

Query  633  ANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGF  682
            ANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GFANTG NN+GF
Sbjct  182  ANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGF  241

Query  683  ANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNW  742
             N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N 
Sbjct  242  GNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNT  301

Query  743  GIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNT  802
            GIGN+          G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NT
Sbjct  302  GIGNT----------GNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNT  351

Query  803  GYFNTGD  809
            GY N G+
Sbjct  352  GYLNIGN  358


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  1950  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2009

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2010  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2069

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2070  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2129

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2130  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2187


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2168  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2215

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2216  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2258


 Score = 56.2 bits (134),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 75/189 (40%), Positives = 97/189 (52%), Gaps = 21/189 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GF N+G+   G AN+G+   G+ N+G  ++   +T + N G  N G+N  G+   G G  
Sbjct  79   GFLNVGALGSGVANVGNTISGIYNVGTSDL---STPAVNSGLANIGTNIAGLLRDGAG--  133

Query  281  GFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNT----------GST  330
                  + + N+GL N G+ NVG  + G  NFG    G  N G+GNT          GS 
Sbjct  134  ------TAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  187

Query  331  NTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNV  390
            N G+ N GD N G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ 
Sbjct  188  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  247

Query  391  NTGAFIAGN  399
            N G  + GN
Sbjct  248  NVGIGLTGN  256


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2085  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2144

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2145  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2204

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2205  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2261

Query  356   NT  357
              T
Sbjct  2262  GT  2263


>gi|308376358|ref|ZP_07668254.1| hypothetical protein TMHG_03315 [Mycobacterium tuberculosis SUMu008]
 gi|308351333|gb|EFP40184.1| hypothetical protein TMHG_03315 [Mycobacterium tuberculosis SUMu008]
Length=2271

 Score =  705 bits (1820),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  177  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  236

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  237  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  296

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  297  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  356

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  357  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  414

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  415  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  474

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  475  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  531

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  532  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  591

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  592  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  651

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  652  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  711

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  712  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  771

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  772  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  831

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  832  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  864


 Score =  670 bits (1729),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1024  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1083

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1084  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1143

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1144  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1203

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1204  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1262

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1263  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1322

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1323  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1382

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1383  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1442

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1443  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1502

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  1503  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  1552

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  1553  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1612

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1613  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1663


 Score =  629 bits (1622),  Expect = 9e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  629   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  688

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  689   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  748

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  749   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  798

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  799   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  858

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  859   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAKNNIDFTPIIIPTINITLPTAAITVG  912

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  913   GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  962

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  963   GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1022

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1023  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1082

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1083  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1132

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1133  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1182

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1183  TGSFNTGGFNAGNTNTGHFNTGN  1205


 Score =  609 bits (1570),  Expect = 8e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1427  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1484

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  1485  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  1544

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1545  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1604

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  1605  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  1664

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  1665  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  1723

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  1724  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  1773

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  1774  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  1833

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  1834  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  1893

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  1894  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  1953

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  1954  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  2013

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  2014  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2073

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2074  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  2133

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  2134  TGYLNTGDYNTGVANTGDVD  2153


 Score =  364 bits (935),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 232/367 (64%), Positives = 261/367 (72%), Gaps = 50/367 (13%)

Query  483  ITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFG  542
            + VGGPTT I+   T +V  ++IP+I IPA PGFGNST   SSGFFN+GAG+ASGFGNFG
Sbjct  2    VMVGGPTTAINIGATVVVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGAGSASGFGNFG  61

Query  543  GGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------  596
            G ASGF NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NS      
Sbjct  62   GAASGFMNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIG  121

Query  597  ----GLLHHSVGTMTLNFGLAN--------------------VGGNNVGGANAGIFNVGL  632
                GLL    GT  +N GLAN                    +G NNVG  N GIF+VGL
Sbjct  122  TNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGL  181

Query  633  ANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGF  682
            ANLG YNIGFGNLG DNLGF + GSYNIGF N G++NL          GFANTG NN+GF
Sbjct  182  ANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGF  241

Query  683  ANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNW  742
             N GSNN+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N 
Sbjct  242  GNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNT  301

Query  743  GIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNT  802
            GIGN+          G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NT
Sbjct  302  GIGNT----------GNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNT  351

Query  803  GYFNTGD  809
            GY N G+
Sbjct  352  GYLNIGN  358


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  1950  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  2009

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  2010  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2069

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2070  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2129

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2130  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2187


 Score = 85.1 bits (209),  Expect = 7e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2168  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2215

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2216  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2258


 Score = 56.2 bits (134),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 75/189 (40%), Positives = 97/189 (52%), Gaps = 21/189 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GF N+G+   G AN+G+   G+ N+G  ++   +T + N G  N G+N  G+   G G  
Sbjct  79   GFLNVGALGSGVANVGNTISGIYNVGTSDL---STPAVNSGLANIGTNIAGLLRDGAG--  133

Query  281  GFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNT----------GST  330
                  + + N+GL N G+ NVG  + G  NFG    G  N G+GNT          GS 
Sbjct  134  ------TAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  187

Query  331  NTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNV  390
            N G+ N GD N G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ 
Sbjct  188  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  247

Query  391  NTGAFIAGN  399
            N G  + GN
Sbjct  248  NVGIGLTGN  256


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2085  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2144

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2145  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2204

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2205  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2261

Query  356   NT  357
              T
Sbjct  2262  GT  2263


>gi|167967605|ref|ZP_02549882.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=2255

 Score =  705 bits (1820),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  161  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  220

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  221  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  280

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  281  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  340

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  341  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  398

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  399  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  458

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  459  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  515

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  516  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  575

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  576  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  635

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  636  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  695

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  696  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  755

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  756  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  815

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  816  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  848


 Score =  671 bits (1730),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/651 (64%), Positives = 487/651 (75%), Gaps = 38/651 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  1008  LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1067

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1068  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1127

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1128  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1187

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1188  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1246

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1247  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1306

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1307  TAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1366

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1367  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1426

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1427  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1486

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQIGFGS NSGSHNIGLF
Sbjct  1487  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIGFGSFNSGSHNIGLF  1536

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDL-----  770
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++     
Sbjct  1537  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1596

Query  771   NTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             NTGS+N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1597  NTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1647


 Score =  629 bits (1622),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  613   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  672

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  673   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  732

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  733   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  782

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  783   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  842

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  843   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  896

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  897   GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  946

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  947   GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  1006

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  1007  TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1066

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1067  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1116

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1117  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1166

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1167  TGSFNTGGFNAGNTNTGHFNTGN  1189


 Score =  609 bits (1571),  Expect = 7e-172, Method: Compositional matrix adjust.
 Identities = 415/740 (57%), Positives = 479/740 (65%), Gaps = 109/740 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1411  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1468

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  1469  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  1528

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1529  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1588

Query  337   --------------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
                           TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNT
Sbjct  1589  GNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNT  1648

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----  437
             GVANTGNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI      
Sbjct  1649  GVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITG  1707

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG---  494
              V+    +  TIPG ++         V  GP  +  + +  P +TI V      ID    
Sbjct  1708  TVVATTPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQ  1757

Query  495   ---NLTGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFW  549
                ++ G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  
Sbjct  1758  QTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSG  1817

Query  550   NLASATSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----  597
             N  +  SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG    
Sbjct  1818  NFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANI  1877

Query  598   ------LLHHSVGTMTLNFGLAN-------------------------------------  614
                   L   + G +TLNFG+AN                                     
Sbjct  1878  GANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFG  1937

Query  615   ---VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG  671
                +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLG
Sbjct  1938  GVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLG  1997

Query  672   FANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGN  731
             FANTG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN
Sbjct  1998  FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGN  2057

Query  732   FGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GI N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS N
Sbjct  2058  VGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGN  2117

Query  792   TGGFNAGNYNTGYFNTGDLQ  811
             TG  N G+YNTG  NTGD+ 
Sbjct  2118  TGYLNTGDYNTGVANTGDVD  2137


 Score =  353 bits (907),  Expect = 7e-95, Method: Compositional matrix adjust.
 Identities = 224/351 (64%), Positives = 251/351 (72%), Gaps = 50/351 (14%)

Query  499  MVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGL  558
            +V  ++IP+I IPA PGFGNST   SSGFFN+GAG+ASGFGNFGG ASGF NL S TSG+
Sbjct  2    VVDAINIPIIHIPATPGFGNSTGGLSSGFFNSGAGSASGFGNFGGAASGFMNLVSTTSGM  61

Query  559  SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHHSVGTMTL  608
            SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NS          GLL    GT  +
Sbjct  62   SGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAI  121

Query  609  NFGLAN--------------------VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGD  648
            N GLAN                    +G NNVG  N GIF+VGLANLG YNIGFGNLG D
Sbjct  122  NLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDD  181

Query  649  NLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGFANIGSNNIGIGLTGSG  698
            NLGF + GSYNIGF N G++NL          GFANTG NN+GF N GSNN+GIGLTG+G
Sbjct  182  NLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNG  241

Query  699  QIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAG  758
            QIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N GIGN+          G
Sbjct  242  QIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNT----------G  291

Query  759  STNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            +TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NTGY N G+
Sbjct  292  NTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIGN  342


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  1934  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  1993

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  1994  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  2053

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  2054  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2113

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2114  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2171


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2152  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2199

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2200  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2242


 Score = 55.8 bits (133),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 75/189 (40%), Positives = 97/189 (52%), Gaps = 21/189 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GF N+G+   G AN+G+   G+ N+G  ++   +T + N G  N G+N  G+   G G  
Sbjct  63   GFLNVGALGSGVANVGNTISGIYNVGTSDL---STPAVNSGLANIGTNIAGLLRDGAG--  117

Query  281  GFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNT----------GST  330
                  + + N+GL N G+ NVG  + G  NFG    G  N G+GNT          GS 
Sbjct  118  ------TAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  171

Query  331  NTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNV  390
            N G+ N GD N G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ 
Sbjct  172  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  231

Query  391  NTGAFIAGN  399
            N G  + GN
Sbjct  232  NVGIGLTGN  240


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2069  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2128

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2129  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2188

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2189  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2245

Query  356   NT  357
              T
Sbjct  2246  GT  2247


>gi|289568216|ref|ZP_06448443.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289541969|gb|EFD45618.1| PPE family protein [Mycobacterium tuberculosis T17]
Length=2199

 Score =  705 bits (1819),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/693 (62%), Positives = 503/693 (73%), Gaps = 61/693 (8%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
            F++GLAN+G+ N+G GN+G  N+GFGN GSYN+GF N+G+DNLG AN GG NIGFANTGS
Sbjct  110  FDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGS  169

Query  258  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
            NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGS NIGLFNSGS N+G FNSG+GNFGI NS
Sbjct  170  NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANS  229

Query  318  GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
            G+ N G+GNTG+TNTG FN+GDVNTG FNPGS+NTG+FNTG++NTG FN GN NTGY N 
Sbjct  230  GSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNI  289

Query  378  GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
            G+YNTG+ANTG+V+TGAFI GNYSNG+   GDYQGL+G ++ +++P +PI+  + ++PI 
Sbjct  290  GNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMP-LPISLGV-NIPID  347

Query  438  QVMVMPGSVMTIPGMRLP------FTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTT  491
              +      +T+ G+ +P       +SI     ++GP+ +P  T+  PT T+ +GGP T 
Sbjct  348  IPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTA  407

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            I   +TG  G + IPLI IPAAPGFGNSTT+PSSGFFN GAG ASGFGNFGG  SGFWNL
Sbjct  408  IT--ITGG-GAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNL  464

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHH  601
            ASATSG SG  NVGALGSG+ANVG T+SG YNTSTS+LATPAFNS          GLL  
Sbjct  465  ASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRD  524

Query  602  SVGTMTLNFGL------------------------------ANVGGNNVGGANAGIFNVG  631
            S GTM LN GL                              AN+GGNN+GGAN GIF++G
Sbjct  525  STGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIG  584

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
            LANLG YNIGFGN G DNLGF + GSYN+GF N G++NLGFANTG NNIGFAN GSNNIG
Sbjct  585  LANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIG  644

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG-  750
            IGLTG GQIGFGSLNSGS NIGLFNSG GNIG FNSG+GN GIGN GT N+G+GN+G+  
Sbjct  645  IGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTN  704

Query  751  ---------NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
                     N GIGN GS NTG FN GD NTG  NPGSYNTG  NTG V+TG F +G+Y+
Sbjct  705  TGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYS  764

Query  802  TGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRP  834
             G+  +G+ Q   G H         L      P
Sbjct  765  NGFLWSGNYQGLIGLHAALAIPEIALTFGVDIP  797


 Score =  687 bits (1772),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/646 (64%), Positives = 484/646 (75%), Gaps = 33/646 (5%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              NLGLAN+G+NN G GN G+F+VG  NLG+YN+GF N G DNLG ANLG +NIG ANTGS
Sbjct  957   LNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGS  1016

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
             NN+GF NTGSNN+GIGLTG GQIG G+ NSGS NIGLFNSG GN+G FNSGTGNFGIGN+
Sbjct  1017  NNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNT  1076

Query  318   GTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNT  377
             GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTGNFNTG++NTG FNAGN NTG+FNT
Sbjct  1077  GTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNT  1136

Query  378   GDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH  437
             G+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGLIG   AL IP IP +  + ++PI 
Sbjct  1137  GNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDV-NIPID  1195

Query  438   QVMVMPGSVMTIPGMRLPFTSIVPFVVYY--------GPVELPQSTLTLPTVTITVGGPT  489
               +    + + +    +P      F   +        GP+ +P   L++PT  I VGGPT
Sbjct  1196  IPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPT  1255

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             T I+ + T  +G ++IP+I IPAAPG GNSTTSPSSGFFN GAGTASGFGN GG  SG W
Sbjct  1256  TAINISATAGLGPITIPVIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLW  1315

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS------GLLHHSV  603
             NLASA SG+SG  NVGALGSGVANVGNTISG+YNTS  +L TPAF S      GLL    
Sbjct  1316  NLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGA  1375

Query  604   GTMT--------LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
             GT          LN GLAN+GG+N G  N GIFNVG AN+G++NIG  NLG  ++GFA++
Sbjct  1376  GTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANS  1435

Query  656   GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
             G+Y+IG ANTGS N+GFANT          GS NIGIGLTG+GQI FGS NSGSHNIGLF
Sbjct  1436  GNYHIGIANTGSANIGFANT----------GSGNIGIGLTGTGQIEFGSFNSGSHNIGLF  1485

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSL  775
             NSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N G+GN GSTNTGLFN G++NTG  
Sbjct  1486  NSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVG  1545

Query  776   NPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             N GS NTGS NTGS NTG FN G++NTG FN+GD    +     Y 
Sbjct  1546  NTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYN  1591


 Score =  628 bits (1620),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 392/623 (63%), Positives = 461/623 (74%), Gaps = 58/623 (9%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGF------  252
             N G AN+G NN+G  N G+F++G  NLGSYN+GF N G DNLG  NLG +N+GF      
Sbjct  562   NFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGND  621

Query  253   ----ANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                 ANTGSNN+GF NTGSNN+GIGLTG+GQIGFGS NSGS NIGLFNSGSGN+G FNSG
Sbjct  622   NLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSG  681

Query  309   TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
              GN GIGN+GT NFGLGNTGSTNTG+FN+GDVNTG         G  NTG++NTGSFN G
Sbjct  682   NGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTG--------IG--NTGSFNTGSFNPG  731

Query  369   NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
             + NTG FN G YNTG+ NTG+V+TGAFI+G+YSNG LW G+YQGLIG   AL IP I + 
Sbjct  732   DSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALT  791

Query  429   AQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFV--VYYGPVELPQSTLTLPTVTITVG  486
               +  +PIH  + +   V+T+ G      SIV     + + P+ +P   +TLPT  ITVG
Sbjct  792   FGV-DIPIHIPINIDAGVVTLQGF-----SIVAAENNIDFTPIIIPTINITLPTAAITVG  845

Query  487   GPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGAS  546
             GPTT+I    +  +G ++IP+I IPA  GFGNSTTSPSSGFFN+GAG+          AS
Sbjct  846   GPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGS----------AS  895

Query  547   GFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM  606
             GF N+ +  SG+SG+ NVGALGSGV NVG+T+SG YN S  +L TPAF SGL+   +GTM
Sbjct  896   GFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTM  955

Query  607   TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
             TLN GLAN+G NN G  N GIF+VG+ANLG+YNIGFGN G DNLGFA+ GSYNIG ANTG
Sbjct  956   TLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTG  1015

Query  667   SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
             SNN+GFANT          GSNNIGIGLTG+GQIG G+LNSGS NIGLFNSGDGNIG FN
Sbjct  1016  SNNIGFANT----------GSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFN  1065

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVN  786
             SG+GNFGIGN GT          GNFGIGN+GST+TGLFNSGD NTG  NPG++NTG+ N
Sbjct  1066  SGTGNFGIGNTGT----------GNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFN  1115

Query  787   TGSVNTGGFNAGNYNTGYFNTGD  809
             TGS NTGGFNAGN NTG+FNTG+
Sbjct  1116  TGSFNTGGFNAGNTNTGHFNTGN  1138


 Score =  612 bits (1577),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  1360  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  1417

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQI FGSFNS
Sbjct  1418  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIEFGSFNS  1477

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  1478  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  1537

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  1538  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  1597

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  1598  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  1656

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  1657  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  1706

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  1707  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  1766

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  1767  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  1826

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  1827  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  1886

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  1887  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  1946

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  1947  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  2006

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  2007  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  2066

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  2067  TGDYNTGVANTGDVD  2081


 Score =  289 bits (739),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 188/301 (63%), Positives = 209/301 (70%), Gaps = 50/301 (16%)

Query  549  WNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL----------  598
             NL S TSG+SGF NVGALGSGVANVGNTISG+YN  TS+L+TPA NSGL          
Sbjct  1    MNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGL  60

Query  599  LHHSVGTMTLNFGLAN--------------------VGGNNVGGANAGIFNVGLANLGDY  638
            L    GT  +N GLAN                    +G NNVG  N GIF+VGLANLG Y
Sbjct  61   LRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSY  120

Query  639  NIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL----------GFANTGDNNIGFANIGSN  688
            NIGFGNLG DNLGF + GSYNIGF N G++NL          GFANTG NN+GF N GSN
Sbjct  121  NIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSN  180

Query  689  NIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSG  748
            N+GIGLTG+GQIGFGS NSGS NIGLFNSG  NIG FNSGSGNFGI N+G+ N GIGN+ 
Sbjct  181  NVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNT-  239

Query  749  AGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
                     G+TNTGLFNSGD+NTG+ NPGS+NTGS NTGS NTGGFN GN NTGY N G
Sbjct  240  ---------GNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIG  290

Query  809  D  809
            +
Sbjct  291  N  291


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  1878  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  1937

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  1938  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  1997

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  1998  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  2057

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  2058  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  2115


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  2096  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  2143

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  2144  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  2186


 Score = 53.5 bits (127),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 71/186 (39%), Positives = 92/186 (50%), Gaps = 10/186 (5%)

Query  641   GFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQI  700
             GFGN+GG+      +G +N+  A +G +  G  N G    G AN+G+   GI  T    +
Sbjct  1303  GFGNVGGN-----TSGLWNLASAASGVS--GLLNVGALGSGVANVGNTISGIYNTSPLDL  1355

Query  701   GFGSLNSGSHNI-GLFNSGDGNIGLFNSGSGNFGIG--NAGTGNWGIGNSGAGNFGIGNA  757
             G  +  SG  NI GL   G G   L  +G GN  +G  N G  N+GIGN+G  N G  N 
Sbjct  1356  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANV  1415

Query  758   GSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEH  817
             G+ N GL N G+ + G  N G+Y+ G  NTGS N G  N G+ N G   TG  Q   G  
Sbjct  1416  GNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIEFGSF  1475

Query  818   RQYQHR  823
                 H 
Sbjct  1476  NSGSHN  1481


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  2013  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  2072

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  2073  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  2132

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  2133  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  2189

Query  356   NT  357
              T
Sbjct  2190  GT  2191


 Score = 38.9 bits (89),  Expect = 4.9, Method: Compositional matrix adjust.
 Identities = 60/178 (34%), Positives = 70/178 (40%), Gaps = 56/178 (31%)

Query  278  GQIGFGSFNSGSHNIG-----------------LFNSGSGNV-----GLFNSGTG-----  310
            G +  G+  SG  N+G                   NSG  N+     GL   G G     
Sbjct  12   GFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAIN  71

Query  311  -----------------------------NFGIGNSGTGNFGLGNTGSTNTGWFNTGDVN  341
                                         N GIGN+G  + GL N GS N G+ N GD N
Sbjct  72   LGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDN  131

Query  342  TGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGN  399
             G  N GSYN G  N GN N G  NAG  N G+ NTG  N G  NTG+ N G  + GN
Sbjct  132  LGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGN  189


>gi|240171832|ref|ZP_04750491.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=1134

 Score =  673 bits (1736),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 490/901 (55%), Positives = 581/901 (65%), Gaps = 98/901 (10%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            MDF VS PE+NS RM+ GAGSGPML AA AWD LA+EL  AA+  GSVT+G+A  +W+GP
Sbjct  1    MDFSVSPPEINSARMFAGAGSGPMLQAATAWDALANELRTAAASVGSVTTGIALGSWQGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            AA AMA A APYLGWL +A AQAEQAAAQA  AV+ FEAA AA VHP  +AANR+ L+SL
Sbjct  61   AAAAMAAAAAPYLGWLQTAAAQAEQAAAQASTAVSAFEAALAAIVHPGCIAANRSRLLSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            V SNLLG NAPAIA+ EA YE+MWAQDVAAM GYH+GAS   +AL PFT+ L+ LAG   
Sbjct  121  VVSNLLGQNAPAIASAEANYEQMWAQDVAAMFGYHSGASGVAAALTPFTRPLQSLAGQVS  180

Query  181  RLTSAAAAAAG------------PPS-------AAGFNLGLANVG------AN----NVG  211
            RL  A A  A              PS       ++ FN+G AN+G      AN    N G
Sbjct  181  RLGGAVAGVASPASAGVAAAAATEPSGLLPSGVSSIFNIGFANLGGLSFGNANLGDLNQG  240

Query  212  NGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVG  271
            NGNVG  N G GNLGS+NLG  NLGS N+GL NLG +N GF NTGS N+GFGNTGS N+G
Sbjct  241  NGNVGNLNFGSGNLGSFNLGSGNLGSFNVGLGNLGSNNFGFGNTGSFNIGFGNTGSGNIG  300

Query  272  -----------------------IGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
                                   IGL G+ Q+GFG  NSG+ N GLFNSGS N G  NSG
Sbjct  301  IGNTGNGNVGFGNGGLGGDNNIGIGLGGSNQLGFGGLNSGTGNTGLFNSGSDNTGFGNSG  360

Query  309  TGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAG  368
            TGNFG+GNSG+ N G GN+G  NTG++N G VNTG  N G+YNTGN+N GN+NTG FN G
Sbjct  361  TGNFGLGNSGSFNTGFGNSGRANTGFYNAGIVNTGIGNVGNYNTGNYNVGNFNTGDFNPG  420

Query  369  NYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN  428
            + NTG +NTG+ NTG ANTG++NTGAF  G+ +NG   RGD  G  G    + IP IPIN
Sbjct  421  DTNTGSYNTGNINTGWANTGDLNTGAFNIGDMNNGFFGRGDGAGNAGFSYTMTIPEIPIN  480

Query  429  AQLFSMPIH--------QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPT  480
              L S+P+H        ++++ P     IP + L F ++   V   GP+++P   +T P 
Sbjct  481  LPL-SVPLHIPVEGRTTEIVLAP---FKIPAIPLDFPALSGTV---GPIQMPPIRVTGPF  533

Query  481  VTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGN  540
            ++ITVG P T +  ++ G VG ++IP+I IPA PGFGNST +PSSGFFN+G G  SGFGN
Sbjct  534  ISITVGSPETRLGVSVAGGVGPINIPIINIPATPGFGNSTDAPSSGFFNSGRGGTSGFGN  593

Query  541  FGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL--  598
            FG   SGF+N  +   G SG  N G L SG+ N GN+ISG  NTS  +L   A NSGL  
Sbjct  594  FGPDTSGFFNF-TRNLGSSGLLNAGLLQSGIHNFGNSISGFENTSNLDLEFRALNSGLGN  652

Query  599  --------LHHSVGTMTLNFGLANVGGNNVGGANAGIFNVG-------------------  631
                     H+S G  T N G AN GG N G AN G FN+G                   
Sbjct  653  VGSRLSGIFHNSSGASTFNLGSANGGGLNFGSANLGSFNLGNGNIGGFNIGDANHGSANF  712

Query  632  -LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNI  690
              AN GD N GFGNLG  NLGF + G  NIGF NTG  N+GF NTG  NIG AN G+ N 
Sbjct  713  GFANFGDNNFGFGNLGDFNLGFGNTGVGNIGFGNTGDYNIGFGNTGSGNIGLANTGNGNS  772

Query  691  GIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG  750
            G+G TGS   GFG LNSG++N GLFNSGDGN G FNSG GNFGIGN G+ N GIGN+   
Sbjct  773  GVGFTGSNLFGFGGLNSGTNNTGLFNSGDGNTGFFNSGEGNFGIGNTGSYNTGIGNTSTA  832

Query  751  NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDL  810
            N GIGN GS NTGLFNSG LNTG  N GS NTG++NTG +NTG FN G+ NTGY+N G+L
Sbjct  833  NTGIGNTGSFNTGLFNSGSLNTGLSNAGSTNTGNLNTGGLNTGDFNTGSGNTGYYNNGNL  892

Query  811  Q  811
             
Sbjct  893  N  893


 Score =  292 bits (747),  Expect = 3e-76, Method: Compositional matrix adjust.
 Identities = 209/460 (46%), Positives = 271/460 (59%), Gaps = 48/460 (10%)

Query  173   KKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVG-----------  221
              +L+G+    + A+    G  +  G N G AN+G+ N+GNGN+G FN+G           
Sbjct  655   SRLSGIFHNSSGASTFNLGSANGGGLNFGSANLGSFNLGNGNIGGFNIGDANHGSANFGF  714

Query  222   ---------FGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGI  272
                      FGNLG +NLGF N G  N+G  N G +NIGF NTGS N+G  NTG+ N G+
Sbjct  715   ANFGDNNFGFGNLGDFNLGFGNTGVGNIGFGNTGDYNIGFGNTGSGNIGLANTGNGNSGV  774

Query  273   GLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNT  332
             G TG+   GFG  NSG++N GLFNSG GN G FNSG GNFGIGN+G+ N G+GNT + NT
Sbjct  775   GFTGSNLFGFGGLNSGTNNTGLFNSGDGNTGFFNSGEGNFGIGNTGSYNTGIGNTSTANT  834

Query  333   GWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNT  392
             G  NTG  NTG FN GS NTG  N G+ NTG+ N G  NTG FNTG  NTG  N GN+NT
Sbjct  835   GIGNTGSFNTGLFNSGSLNTGLSNAGSTNTGNLNTGGLNTGDFNTGSGNTGYYNNGNLNT  894

Query  393   GAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQL---FSMP----IHQVMVMPGS  445
             GAF +GN +NG  WR D +G  G D  + +P IP+N  +    ++P    I  + V P S
Sbjct  895   GAFNSGNRNNGYFWRADDRGQFGFDFGITMPGIPLNIGVNVDLAIPVTGFIDGIAVQPFS  954

Query  446   VMTIP---GMRLPFTSIVPFVVYYGPVELPQS-TLTLPTVTI-----------TVGG-PT  489
              M +P    + +   S +P V    P+   +S T+ +P + I            VGG P 
Sbjct  955   -MDVPIDLNLFIDLPSPIPNVTI--PLGDGESITVEIPKIVINRFDLTGFNVGNVGGIPF  1011

Query  490   TTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFW  549
             + +   +   VG +S+P++ IPAAPG GNST +P+SGFFN+G G  SGF N G   SGF 
Sbjct  1012  SRMHIEIINNVGPISVPILHIPAAPGVGNSTINPTSGFFNSGPGAGSGFFNAGQFISGFS  1071

Query  550   NLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNL  589
             N       LSGF N+G L SG+ N+GN ++G YNTST+ L
Sbjct  1072  NEGGRF--LSGFENIGQLTSGMGNIGNIVTGWYNTSTAGL  1109


 Score =  163 bits (413),  Expect = 1e-37, Method: Compositional matrix adjust.
 Identities = 126/250 (51%), Positives = 149/250 (60%), Gaps = 34/250 (13%)

Query  596  SGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHA  655
            SGLL   V ++  N G AN+GG + G AN G  N G  N+G+ N G GNLG  NLG  + 
Sbjct  206  SGLLPSGVSSI-FNIGFANLGGLSFGNANLGDLNQGNGNVGNLNFGSGNLGSFNLGSGNL  264

Query  656  GSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG-----------------------I  692
            GS+N+G  N GSNN GF NTG  NIGF N GS NIG                       I
Sbjct  265  GSFNVGLGNLGSNNFGFGNTGSFNIGFGNTGSGNIGIGNTGNGNVGFGNGGLGGDNNIGI  324

Query  693  GLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNF  752
            GL GS Q+GFG LNSG+ N GLFNSG  N G  NSG+GNFG+GN+G+ N G GNSG  N 
Sbjct  325  GLGGSNQLGFGGLNSGTGNTGLFNSGSDNTGFGNSGTGNFGLGNSGSFNTGFGNSGRANT  384

Query  753  G----------IGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNT  802
            G          IGN G+ NTG +N G+ NTG  NPG  NTGS NTG++NTG  N G+ NT
Sbjct  385  GFYNAGIVNTGIGNVGNYNTGNYNVGNFNTGDFNPGDTNTGSYNTGNINTGWANTGDLNT  444

Query  803  GYFNTGDLQH  812
            G FN GD+ +
Sbjct  445  GAFNIGDMNN  454


 Score = 54.3 bits (129),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 67/179 (38%), Positives = 82/179 (46%), Gaps = 24/179 (13%)

Query  537  GFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS  596
            GFGN G G  G  N  +  SG+ GF      G G  N G   +GL+N+   N  T  FNS
Sbjct  753  GFGNTGSGNIGLANTGNGNSGV-GFTGSNLFGFGGLNSGTNNTGLFNSGDGN--TGFFNS  809

Query  597  GLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAG  656
            G           NFG+ N G  N G  N    N G+ N G +N G  N G  N G ++AG
Sbjct  810  G---------EGNFGIGNTGSYNTGIGNTSTANTGIGNTGSFNTGLFNSGSLNTGLSNAG  860

Query  657  SYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
            S N G  NTG  N G  NTG  N G+ N            +G +  G+ NSG+ N G F
Sbjct  861  STNTGNLNTGGLNTGDFNTGSGNTGYYN------------NGNLNTGAFNSGNRNNGYF  907


 Score = 41.2 bits (95),  Expect = 1.0, Method: Compositional matrix adjust.
 Identities = 61/203 (31%), Positives = 77/203 (38%), Gaps = 78/203 (38%)

Query  703  GSLNSGSHNIG----------------------------LFNSGDGNIGLFNSGSGNF--  732
            G L SG  +I                               N G GN+G FN GSGN   
Sbjct  207  GLLPSGVSSIFNIGFANLGGLSFGNANLGDLNQGNGNVGNLNFGSGNLGSFNLGSGNLGS  266

Query  733  ---GIGNAGTGNWGIGNSGAGNFGIGNAGST-----------------------------  760
               G+GN G+ N+G GN+G+ N G GN GS                              
Sbjct  267  FNVGLGNLGSNNFGFGNTGSFNIGFGNTGSGNIGIGNTGNGNVGFGNGGLGGDNNIGIGL  326

Query  761  ----------------NTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGY  804
                            NTGLFNSG  NTG  N G+ N G  N+GS NTG  N+G  NTG+
Sbjct  327  GGSNQLGFGGLNSGTGNTGLFNSGSDNTGFGNSGTGNFGLGNSGSFNTGFGNSGRANTGF  386

Query  805  FNTGDLQHRHGEHRQYQHRRFHL  827
            +N G +    G    Y    +++
Sbjct  387  YNAGIVNTGIGNVGNYNTGNYNV  409


 Score = 39.3 bits (90),  Expect = 3.4, Method: Compositional matrix adjust.
 Identities = 32/63 (51%), Positives = 37/63 (59%), Gaps = 3/63 (4%)

Query  751  NFGIGNAGSTNTGLF-NSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            N G+GN GS  +G+F NS   +T   N GS N G +N GS N G FN GN N G FN GD
Sbjct  647  NSGLGNVGSRLSGIFHNSSGAST--FNLGSANGGGLNFGSANLGSFNLGNGNIGGFNIGD  704

Query  810  LQH  812
              H
Sbjct  705  ANH  707


>gi|289445843|ref|ZP_06435587.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289418801|gb|EFD16002.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=1147

 Score =  612 bits (1579),  Expect = 7e-173, Method: Compositional matrix adjust.
 Identities = 416/735 (57%), Positives = 480/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  308   FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  365

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  366   HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  425

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  426   GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  485

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  486   GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  545

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  546   GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  604

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  605   TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  654

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  655   VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  714

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  715   NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  774

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  775   GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  834

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  835   GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  894

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  895   SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  954

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  955   TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  1014

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  1015  TGDYNTGVANTGDVD  1029


 Score =  549 bits (1415),  Expect = 8e-154, Method: Compositional matrix adjust.
 Identities = 341/550 (62%), Positives = 406/550 (74%), Gaps = 33/550 (6%)

Query  294  LFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTG  353
            +FNSG GN+G FNSGTGNFGIGN+GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTG
Sbjct  1    MFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTG  60

Query  354  NFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGL  413
            NFNTG++NTG FNAGN NTG+FNTG+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGL
Sbjct  61   NFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGL  120

Query  414  IGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYY-------  466
            IG   AL IP IP +  + ++PI   +    + + +    +P      F   +       
Sbjct  121  IGYSYALTIPEIPAHLDV-NIPIDIPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPD  179

Query  467  -GPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
             GP+ +P   L++PT  I VGGPTT I+ + T  +G ++IP+I IPAAPG GNSTTSPSS
Sbjct  180  IGPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSS  239

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GFFN GAGTASGFGN GG  SG WNLASA SG+SG  NVGALGSGVANVGNTISG+YNTS
Sbjct  240  GFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVANVGNTISGIYNTS  299

Query  586  TSNLATPAFNS------GLLHHSVGTMT--------LNFGLANVGGNNVGGANAGIFNVG  631
              +L TPAF S      GLL    GT          LN GLAN+GG+N G  N GIFNVG
Sbjct  300  PLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVG  359

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             AN+G++NIG  NLG  ++GFA++G+Y+IG ANTGS N+GFANT          GS NIG
Sbjct  360  FANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANT----------GSGNIG  409

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGN  751
            IGLTG+GQIGFGS NSGSHNIGLFNSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N
Sbjct  410  IGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFN  469

Query  752  FGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
             G+GN GSTNTGLFN G++NTG  N GS NTGS NTGS NTG FN G++NTG FN+GD  
Sbjct  470  TGLGNTGSTNTGLFNPGNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYN  529

Query  812  HRHGEHRQYQ  821
              +     Y 
Sbjct  530  TGYFNAGDYN  539


 Score =  263 bits (673),  Expect = 9e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  826   LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  885

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  886   DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  945

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  946   GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  1005

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  1006  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  1063


 Score = 84.7 bits (208),  Expect = 7e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  1044  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  1091

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  1092  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  1134


 Score = 53.1 bits (126),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  961   GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  1020

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  1021  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  1080

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  1081  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  1137

Query  356   NT  357
              T
Sbjct  1138  GT  1139


 Score = 51.6 bits (122),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 75/199 (38%), Positives = 99/199 (50%), Gaps = 22/199 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GFGN+G    G  NL S   G++       G  N G+   G  N G+   GI  T    +
Sbjct  251  GFGNVGGNTSGLWNLASAASGVS-------GLLNVGALGSGVANVGNTISGIYNTSPLDL  303

Query  281  GFGSFNSGSHNI-GLFNSGSGNVGLFNSGTGNFGIG--NSGTGNFGLGNTGSTNTGWFNT  337
            G  +F SG  NI GL   G+G   L  +G GN  +G  N G  NFG+GNTG      FN 
Sbjct  304  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTG-----IFNV  358

Query  338  GDVNTGGFNPGSYNTGNF-----NTGNYNTGSFNAGNYNTGYFNTGDYNTGV--ANTGNV  390
            G  N G  N G  N GN+     N+GNY+ G  N G+ N G+ NTG  N G+    TG +
Sbjct  359  GFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQI  418

Query  391  NTGAFIAGNYSNGVLWRGD  409
              G+F +G+++ G+   GD
Sbjct  419  GFGSFNSGSHNIGLFNSGD  437


>gi|31791483|ref|NP_853976.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121636219|ref|YP_976442.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224988692|ref|YP_002643379.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|31617069|emb|CAD93176.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
 gi|121491866|emb|CAL70329.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224771805|dbj|BAH24611.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341600235|emb|CCC62905.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=1147

 Score =  611 bits (1576),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 416/735 (57%), Positives = 480/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  308   FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  365

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  366   HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  425

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNT  FN 
Sbjct  426   GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTSLFNP  485

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  486   GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  545

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  546   GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  604

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  605   TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  654

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  655   VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  714

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  715   NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  774

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  775   GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  834

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  835   GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  894

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  895   SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  954

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
             AGTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  955   AGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  1014

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  1015  TGDYNTGVANTGDVD  1029


 Score =  547 bits (1409),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 340/550 (62%), Positives = 405/550 (74%), Gaps = 33/550 (6%)

Query  294  LFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTG  353
            +FNSG GN+G FNSGTGNFGIGN+GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTG
Sbjct  1    MFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTG  60

Query  354  NFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGL  413
            NFNTG++NTG FNAGN NTG+FNTG+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGL
Sbjct  61   NFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGL  120

Query  414  IGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYY-------  466
            IG   AL IP IP +  + ++PI   +    + + +    +P      F   +       
Sbjct  121  IGYSYALTIPEIPAHLDV-NIPIDIPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPD  179

Query  467  -GPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
             GP+ +P   L++PT  I VGGPTT I+ + T  +G ++IP+I IPAAPG GNSTTSPSS
Sbjct  180  IGPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSS  239

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GFFN GAGTASGFGN GG  SG WNLASA SG+SG  NVGALGSGVANVGNTISG+YNTS
Sbjct  240  GFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVANVGNTISGIYNTS  299

Query  586  TSNLATPAFNS------GLLHHSVGTMT--------LNFGLANVGGNNVGGANAGIFNVG  631
              +L TPAF S      GLL    GT          LN GLAN+GG+N G  N GIFNVG
Sbjct  300  PLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVG  359

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             AN+G++NIG  NLG  ++GFA++G+Y+IG ANTGS N+GFANT          GS NIG
Sbjct  360  FANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANT----------GSGNIG  409

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGN  751
            IGLTG+GQIGFGS NSGSHNIGLFNSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N
Sbjct  410  IGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFN  469

Query  752  FGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
             G+GN GSTNT LFN G++NTG  N GS NTGS NTGS NTG FN G++NTG FN+GD  
Sbjct  470  TGLGNTGSTNTSLFNPGNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYN  529

Query  812  HRHGEHRQYQ  821
              +     Y 
Sbjct  530  TGYFNAGDYN  539


 Score =  263 bits (672),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  826   LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  885

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  886   DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  945

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  946   GTGNVGIFNAGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  1005

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  1006  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  1063


 Score = 60.8 bits (146),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 103/263 (40%), Positives = 129/263 (50%), Gaps = 35/263 (13%)

Query  537   GFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNS  596
             GFGN G    GF N  S   G   F N G+   G AN GN   G+  T    +   + NS
Sbjct  869   GFGNAGSYNIGFANFGSDNLG---FANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNS  925

Query  597   GLLHHSVGTM---TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLG-------  646
             G   +++G     + N G  N G  NVG  NAG  N GLAN G +N G GN G       
Sbjct  926   G--SNNIGLFNSGSGNIGFFNSGTGNVGIFNAGTGNFGLANSGGFNTGIGNAGSTNTGVF  983

Query  647   --GD-NLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFG  703
               GD N G  + GS+N G  N GS N G+ NTGD N G AN G  + G  +TGS   GF 
Sbjct  984   NPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGF-  1042

Query  704   SLNSGSHN--IGL-----------FN-SGDGNIGLFNSGSGNF-GIGNAGTGNWGIGNSG  748
              L SG +   IGL           FN +G  + G FNSG+G+  G  N+G G  G  N+G
Sbjct  1043  -LVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSGAGLSGYLNTG  1101

Query  749   AGNFGIGNAGSTNTGLFNSGDLN  771
             A   G+ N G+T +G  N+  L+
Sbjct  1102  ALGSGVANVGNTISGWLNASALD  1124


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  961   GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  1020

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  1021  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  1080

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  1081  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  1137

Query  356   NT  357
              T
Sbjct  1138  GT  1139


 Score = 51.2 bits (121),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 75/199 (38%), Positives = 99/199 (50%), Gaps = 22/199 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GFGN+G    G  NL S   G++       G  N G+   G  N G+   GI  T    +
Sbjct  251  GFGNVGGNTSGLWNLASAASGVS-------GLLNVGALGSGVANVGNTISGIYNTSPLDL  303

Query  281  GFGSFNSGSHNI-GLFNSGSGNVGLFNSGTGNFGIG--NSGTGNFGLGNTGSTNTGWFNT  337
            G  +F SG  NI GL   G+G   L  +G GN  +G  N G  NFG+GNTG      FN 
Sbjct  304  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTG-----IFNV  358

Query  338  GDVNTGGFNPGSYNTGNF-----NTGNYNTGSFNAGNYNTGYFNTGDYNTGV--ANTGNV  390
            G  N G  N G  N GN+     N+GNY+ G  N G+ N G+ NTG  N G+    TG +
Sbjct  359  GFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQI  418

Query  391  NTGAFIAGNYSNGVLWRGD  409
              G+F +G+++ G+   GD
Sbjct  419  GFGSFNSGSHNIGLFNSGD  437


>gi|289572891|ref|ZP_06453118.1| PE family protein [Mycobacterium tuberculosis K85]
 gi|289537322|gb|EFD41900.1| PE family protein [Mycobacterium tuberculosis K85]
Length=1147

 Score =  610 bits (1573),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  308   FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  365

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  366   HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  425

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNT  FN 
Sbjct  426   GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTSLFNP  485

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  486   GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  545

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  546   GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  604

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  605   TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  654

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SGF N  + 
Sbjct  655   VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGFGNFGAG  714

Query  555   TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
              SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  715   NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  774

Query  598   -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
              L   + G +TLNFG+AN                                        +G
Sbjct  775   GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  834

Query  617   GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
             GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  835   GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  894

Query  677   DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
               NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  895   SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  954

Query  737   AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
              GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  955   TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  1014

Query  797   AGNYNTGYFNTGDLQ  811
              G+YNTG  NTGD+ 
Sbjct  1015  TGDYNTGVANTGDVD  1029


 Score =  547 bits (1409),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 340/550 (62%), Positives = 405/550 (74%), Gaps = 33/550 (6%)

Query  294  LFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTG  353
            +FNSG GN+G FNSGTGNFGIGN+GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTG
Sbjct  1    MFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTG  60

Query  354  NFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGL  413
            NFNTG++NTG FNAGN NTG+FNTG+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGL
Sbjct  61   NFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGL  120

Query  414  IGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYY-------  466
            IG   AL IP IP +  + ++PI   +    + + +    +P      F   +       
Sbjct  121  IGYSYALTIPEIPAHLDV-NIPIDIPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPD  179

Query  467  -GPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
             GP+ +P   L++PT  I VGGPTT I+ + T  +G ++IP+I IPAAPG GNSTTSPSS
Sbjct  180  IGPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSS  239

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GFFN GAGTASGFGN GG  SG WNLASA SG+SG  NVGALGSGVANVGNTISG+YNTS
Sbjct  240  GFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVANVGNTISGIYNTS  299

Query  586  TSNLATPAFNS------GLLHHSVGTMT--------LNFGLANVGGNNVGGANAGIFNVG  631
              +L TPAF S      GLL    GT          LN GLAN+GG+N G  N GIFNVG
Sbjct  300  PLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVG  359

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             AN+G++NIG  NLG  ++GFA++G+Y+IG ANTGS N+GFANT          GS NIG
Sbjct  360  FANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANT----------GSGNIG  409

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGN  751
            IGLTG+GQIGFGS NSGSHNIGLFNSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N
Sbjct  410  IGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFN  469

Query  752  FGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
             G+GN GSTNT LFN G++NTG  N GS NTGS NTGS NTG FN G++NTG FN+GD  
Sbjct  470  TGLGNTGSTNTSLFNPGNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYN  529

Query  812  HRHGEHRQYQ  821
              +     Y 
Sbjct  530  TGYFNAGDYN  539


 Score =  263 bits (673),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  826   LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  885

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  886   DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  945

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  946   GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  1005

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  1006  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  1063


 Score = 84.7 bits (208),  Expect = 7e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  1044  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  1091

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  1092  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  1134


 Score = 52.8 bits (125),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  961   GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  1020

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  1021  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  1080

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  1081  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  1137

Query  356   NT  357
              T
Sbjct  1138  GT  1139


 Score = 51.2 bits (121),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 75/199 (38%), Positives = 99/199 (50%), Gaps = 22/199 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GFGN+G    G  NL S   G++       G  N G+   G  N G+   GI  T    +
Sbjct  251  GFGNVGGNTSGLWNLASAASGVS-------GLLNVGALGSGVANVGNTISGIYNTSPLDL  303

Query  281  GFGSFNSGSHNI-GLFNSGSGNVGLFNSGTGNFGIG--NSGTGNFGLGNTGSTNTGWFNT  337
            G  +F SG  NI GL   G+G   L  +G GN  +G  N G  NFG+GNTG      FN 
Sbjct  304  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTG-----IFNV  358

Query  338  GDVNTGGFNPGSYNTGNF-----NTGNYNTGSFNAGNYNTGYFNTGDYNTGV--ANTGNV  390
            G  N G  N G  N GN+     N+GNY+ G  N G+ N G+ NTG  N G+    TG +
Sbjct  359  GFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQI  418

Query  391  NTGAFIAGNYSNGVLWRGD  409
              G+F +G+++ G+   GD
Sbjct  419  GFGSFNSGSHNIGLFNSGD  437


>gi|339293360|gb|AEJ45471.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
Length=993

 Score =  610 bits (1572),  Expect = 5e-172, Method: Compositional matrix adjust.
 Identities = 415/735 (57%), Positives = 479/735 (66%), Gaps = 104/735 (14%)

Query  168  FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
            F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  154  FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  211

Query  228  YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
            +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG GQIGFGSFNS
Sbjct  212  HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNS  271

Query  288  GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
            GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  272  GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  331

Query  337  ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                     TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  332  GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  391

Query  388  GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
            GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  392  GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  450

Query  443  PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
              +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  451  TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  500

Query  497  TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG-ASGFWNLASA  554
             G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNFG G  SG  N  + 
Sbjct  501  VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAG  560

Query  555  TSGL--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG---------  597
             SG         SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG         
Sbjct  561  NSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLA  620

Query  598  -LLHHSVGTMTLNFGLAN----------------------------------------VG  616
             L   + G +TLNFG+AN                                        +G
Sbjct  621  GLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIG  680

Query  617  GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
            GNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFANTG
Sbjct  681  GNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTG  740

Query  677  DNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGN  736
              NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI N
Sbjct  741  SYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFN  800

Query  737  AGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFN  796
             GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG  N
Sbjct  801  TGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLN  860

Query  797  AGNYNTGYFNTGDLQ  811
             G+YNTG  NTGD+ 
Sbjct  861  TGDYNTGVANTGDVD  875


 Score =  339 bits (870),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 246/471 (53%), Positives = 285/471 (61%), Gaps = 73/471 (15%)

Query  467  GPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSG  526
            GP+ +P   L++PT  I VGGPTT I+ + T  +G ++IP+I IPAAPG GNSTTSPSSG
Sbjct  27   GPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSG  86

Query  527  FFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTST  586
            FFN GAGTASGFGN GG  SG WNLASA SG+SG  NVGALGSGVANVGNTISG+YNTS 
Sbjct  87   FFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSP  146

Query  587  SNLATPAFNSGL------LHHSVGTMTL--------NFGLANVGGNNVGGANAGIFNVGL  632
             +L TPAF SGL      L    GT  L        N GLAN+GG+N G  N GIFNVG 
Sbjct  147  LDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGF  206

Query  633  ANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGI  692
            AN+G++NIG  NLG  ++GFA++G+Y+IG ANTGS N+GFANTG          S NIGI
Sbjct  207  ANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTG----------SGNIGI  256

Query  693  GLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNF  752
            GLTG+GQIGFGS NSGSHNIGLFNSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N 
Sbjct  257  GLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNT  316

Query  753  GIGNAGSTN----------------------------------------TGLFNSGDLNT  772
            G+GN GSTN                                        TG FNSGD NT
Sbjct  317  GLGNTGSTNTGLFNPGNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNT  376

Query  773  GSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ----HRRFHLR  828
            G  N G YNTG  NTG+VNTG F +GNY+ G+F  GD Q   G            R+ L 
Sbjct  377  GYFNAGDYNTGVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDLS  436

Query  829  QPQQRP---SVAGRQPGS-DRPRHRRRHSRNPDCERRREYPDSHT-DHRQL  874
             P   P   +V    P S   P  + R    P      E     T D  Q+
Sbjct  437  VPIDIPITGTVVATTPNSFTIPGFQIRVLLGPAAVLVNEMIGPITIDVNQV  487


 Score =  265 bits (676),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
             N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  672  LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  731

Query  248  HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  732  DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  791

Query  308  GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
            GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  792  GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  851

Query  368  GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
            G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  852  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  909


 Score = 85.1 bits (209),  Expect = 7e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492  IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
            + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  890  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  937

Query  552  ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  938  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  980


 Score = 53.1 bits (126),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191  GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
            G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  807  GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  866

Query  251  GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
            G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  867  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  926

Query  299  SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
            +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  927  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  983

Query  356  NT  357
             T
Sbjct  984  GT  985


 Score = 52.4 bits (124),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 75/199 (38%), Positives = 99/199 (50%), Gaps = 22/199 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GFGN+G    G  NL S   G++       G  N G+   G  N G+   GI  T    +
Sbjct  97   GFGNVGGNTSGLWNLASAASGVS-------GLLNVGALGSGVANVGNTISGIYNTSPLDL  149

Query  281  GFGSFNSGSHNI-GLFNSGSGNVGLFNSGTGNFGIG--NSGTGNFGLGNTGSTNTGWFNT  337
            G  +F SG  NI GL   G+G   L  +G GN  +G  N G  NFG+GNTG      FN 
Sbjct  150  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTG-----IFNV  204

Query  338  GDVNTGGFNPGSYNTGNF-----NTGNYNTGSFNAGNYNTGYFNTGDYNTGV--ANTGNV  390
            G  N G  N G  N GN+     N+GNY+ G  N G+ N G+ NTG  N G+    TG +
Sbjct  205  GFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQI  264

Query  391  NTGAFIAGNYSNGVLWRGD  409
              G+F +G+++ G+   GD
Sbjct  265  GFGSFNSGSHNIGLFNSGD  283


>gi|183980666|ref|YP_001848957.1| PPE family protein [Mycobacterium marinum M]
 gi|183173992|gb|ACC39102.1| PPE family protein [Mycobacterium marinum M]
Length=2403

 Score =  609 bits (1571),  Expect = 7e-172, Method: Compositional matrix adjust.
 Identities = 458/897 (52%), Positives = 559/897 (63%), Gaps = 128/897 (14%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M FV+  PE+NS RM+LGAG GPMLAAA AWDGLA EL  AAS FG+VTSGLA  +W+GP
Sbjct  1    MSFVLLPPEINSARMHLGAGPGPMLAAATAWDGLAAELFAAASAFGAVTSGLAGGSWQGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            A+ AMA A  PYL WL +A+ QAEQAA+Q R A+A+FEAA  ATV P  + ANR VL +L
Sbjct  61   ASTAMASAAQPYLVWLTTASVQAEQAASQVRAALASFEAALVATVSPPAIDANRTVLTAL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            V++N+LG  APAIAA EA YE+MWAQDVAAM+GYHAGASAA SAL PF      ++GL  
Sbjct  121  VNANVLGLAAPAIAAVEAQYEQMWAQDVAAMLGYHAGASAAASALTPF-----AVSGLVR  175

Query  181  RL-------------------TSAAAAAAGPPSAAGF-NLGLA-----NVGANNVGNGNV  215
            +L                    +A AA A P SA G  +LGLA     N+GA NVG  N+
Sbjct  176  QLGNAAAASLASAAPASAAVAAAAEAAVADPVSALGLPSLGLAAATPLNLGAANVGTSNL  235

Query  216  GV-------------------------FNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
            G                          +N+G+GNLG  N GF N GS+N G AN G +N 
Sbjct  236  GFGNIGSGNIGNGNNGDGNLGGGNLGSYNLGWGNLGGANQGFGNAGSNNQGFANTGSNNQ  295

Query  251  GFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTG  310
            GFANTGS NVGFGNTGSNN+GIGL+G+G+IGFGS NSGS NIGLFNSG+ N+G FNSGTG
Sbjct  296  GFANTGSFNVGFGNTGSNNIGIGLSGDGKIGFGSLNSGSGNIGLFNSGTNNIGFFNSGTG  355

Query  311  NFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNY  370
            NFG+ NSG          S NTG+ N+G+ +TG FNPG+ NTG  NTGN+NTGSFNAGN 
Sbjct  356  NFGVLNSG----------SYNTGFGNSGEASTGVFNPGNANTGWANTGNHNTGSFNAGNT  405

Query  371  NTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQ  430
            NTG FN G+ NTG ANTG+V+TGAFI+G+YSNG+ W+ DY+ L+G D+ +       +  
Sbjct  406  NTGGFNPGNLNTGWANTGDVDTGAFISGSYSNGLFWQDDYR-LLGIDLKINFGGTSGDYA  464

Query  431  LFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTT  490
            + S+P+          +T PG  +P  + +    Y GP+ +P  T+  P +  TVG    
Sbjct  465  V-SIPLDNTFSATVPTITTPGTTIPKQTFLN-GGYIGPITIPSITIVGPPINATVG--PA  520

Query  491  TIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWN  550
            T+D +L+  V  + + L+ IP   G GN+++SPSSGFFN G           GG+SG +N
Sbjct  521  TLDLSLSYDVSPIQLQLLYIPPTTGLGNTSSSPSSGFFNQGD----------GGSSGLFN  570

Query  551  LASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLA--TPAFNS----------GL  598
              S   G+SG  N G L SG  N GNTISG++NTS   LA   PA  S          G+
Sbjct  571  TTSGPFGVSGLLNYGDLESGALNFGNTISGIHNTSGLELAPLEPARISGVGNIGSDLAGV  630

Query  599  LHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLG--------------------DY  638
                    T N G+ N GG N G AN G +N G AN+G                    DY
Sbjct  631  FRDGPDATTFNVGVGNDGGLNFGSANIGDYNFGNANIGNLNLGSANIGFGNIGGGNVGDY  690

Query  639  NIGFGNLGGDNLGFAHAGS------YNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGI  692
            N+G GNLG  N+GF +AG        NIGF NTG NN+GF NTG+ NIGF N G+ NIGI
Sbjct  691  NLGSGNLGSANIGFGNAGPGLTAAFNNIGFGNTGDNNIGFGNTGNGNIGFGNTGNGNIGI  750

Query  693  GLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNF  752
            GL G G  GFG  NSGS          GNIGLFNSG+ N GIGN+GTGN GIGN+G+ N 
Sbjct  751  GLNGDGLQGFGGWNSGS----------GNIGLFNSGTDNVGIGNSGTGNSGIGNTGSYNT  800

Query  753  GIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            GIGN G  NTGLFN G+LNTG  NPG+YN+G+ N GS NTGG N G+YNTG+ N GD
Sbjct  801  GIGNVGVANTGLFNIGNLNTGIGNPGNYNSGAHNVGSTNTGGANQGDYNTGWLNLGD  857


 Score =  486 bits (1252),  Expect = 6e-135, Method: Compositional matrix adjust.
 Identities = 363/738 (50%), Positives = 456/738 (62%), Gaps = 87/738 (11%)

Query  159   SAAVSALMPFTQQLKK--LAGLS-ERLTSAAAAA-----AGPPSAAGFNLGLANVGANNV  210
             +A VS +  F   L    LAG S +R+ +   A       G  +   +N GL NVG  N 
Sbjct  1072  AANVSGVSNFGSNLSGFFLAGDSADRIFNVGVANDGSFNIGSANLGDYNFGLGNVGNTNF  1131

Query  211   GNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGG------HNIGFANTGSNNVG---  261
             G GN+G  N+G  N+G  N GF N+G++N G  N G       HNIGF NTGSNN+G   
Sbjct  1132  GPGNLGSTNIGGANIGDTNFGFGNIGANNFGFGNSGASLTDGNHNIGFGNTGSNNIGIGN  1191

Query  262   -------FGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGI  314
                    FGNTG++N GIGL G+G  GFG +NSGS NIG+FNSG+ NVG+ NSGTGN GI
Sbjct  1192  TGDGNIGFGNTGNDNTGIGLNGDGLQGFGGWNSGSGNIGVFNSGTDNVGIGNSGTGNSGI  1251

Query  315   GNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGY  374
             GNSG+ N G+GN+G  NTG FN+G  NTG  N GSYNTG FN G++NTG+FN G  NTG 
Sbjct  1252  GNSGSYNTGIGNSGLANTGLFNSGSFNTGIGNVGSYNTGTFNVGDHNTGNFNTGQSNTGS  1311

Query  375   FNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIG------------ADIALEI  422
              N GD NTG ANTGNVNTGA I+G+Y+NG+LWRGDYQG +G            AD+ L  
Sbjct  1312  LNVGDLNTGWANTGNVNTGALISGDYNNGLLWRGDYQGNLGAFNYTVTVPTTTADLNLSF  1371

Query  423   P-AIPINAQLFSMPIHQVMVMPGSVMTIPGM---RLPFTSIVPFVVYY----GPVELPQS  474
             P ++PI+  +  + I     +P     + G    ++P    V   +Y+     P+     
Sbjct  1372  PISLPISIDIGKIVIES-FTLPKITANLDGKIKYKIPGVGKVNVKLYWDLKISPITFSDI  1430

Query  475   TLTLPTVTITVGGP--TTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGA  532
             T++ PT+T T+G    +T +  +  G +G ++IPLI IPA PGFGNS+TSPSSGFFN+G 
Sbjct  1431  TISGPTLTSTIGNTDGSTVLGVDTDGTIGPLTIPLIDIPAGPGFGNSSTSPSSGFFNSGD  1490

Query  533   GTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATP  592
             G++SGFGN G   SGF+N+ S   G SG  N G L SG+ N+GN+ISGL NTST ++ TP
Sbjct  1491  GSSSGFGNVGINNSGFFNV-SFIDGNSGLRNYGNLESGLGNLGNSISGLLNTSTLDIDTP  1549

Query  593   A---------------------------FNSGLLHHSV------GTMTLNFGLANVGGNN  619
             A                           FN G     +       T   N G  N+G  N
Sbjct  1550  AVVSGIGNIGTNLSGFYNDASGNAPDSTFNLGFADIGIFNAGAANTGNYNLGFGNIGDGN  1609

Query  620   VGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGS------YNIGFANTGSNNLGFA  673
             VG AN G FN G AN+GD N GFGN+G +N GF ++G+      +NIGF NTGSNN GF 
Sbjct  1610  VGAANVGNFNFGGANIGDTNFGFGNIGNNNFGFGNSGASLTNGNHNIGFGNTGSNNFGFG  1669

Query  674   NTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFG  733
             NTGD NIGF N G  NIGIGL+G G  GFG+LN+GS N+GLFNSG  NIGLFNSGS N G
Sbjct  1670  NTGDGNIGFGNTGDGNIGIGLSGDGLRGFGALNTGSGNVGLFNSGTNNIGLFNSGSDNIG  1729

Query  734   IGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTG  793
             IGN+G GN G+ NSG  + G+ NAG  NTG+ N+GD NTG+ N G  NTG+ N+GS NTG
Sbjct  1730  IGNSGIGNAGLFNSGNYDTGMFNAGIVNTGIGNAGDFNTGTFNAGDANTGNANSGSYNTG  1789

Query  794   GFNAGNYNTGYFNTGDLQ  811
             GFN+GNY+TG+ NTGD+ 
Sbjct  1790  GFNSGNYDTGWANTGDVD  1807


 Score =  452 bits (1162),  Expect = 2e-124, Method: Compositional matrix adjust.
 Identities = 343/706 (49%), Positives = 424/706 (61%), Gaps = 79/706 (11%)

Query  173   KKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVG----------------  216
               LAG+      A     G  +  G N G AN+G  N GN N+G                
Sbjct  625   SDLAGVFRDGPDATTFNVGVGNDGGLNFGSANIGDYNFGNANIGNLNLGSANIGFGNIGG  684

Query  217   ----VFNVGFGNLGSYNLGFANLGS------DNLGLANLGGHNIGFANTGSNNVGFGNTG  266
                  +N+G GNLGS N+GF N G       +N+G  N G +NIGF NTG+ N+GFGNTG
Sbjct  685   GNVGDYNLGSGNLGSANIGFGNAGPGLTAAFNNIGFGNTGDNNIGFGNTGNGNIGFGNTG  744

Query  267   SNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGN  326
             + N+GIGL G+G  GFG +NSGS NIGLFNSG+ NVG+ NSGTGN GIGN+G+ N G+GN
Sbjct  745   NGNIGIGLNGDGLQGFGGWNSGSGNIGLFNSGTDNVGIGNSGTGNSGIGNTGSYNTGIGN  804

Query  327   TGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVAN  386
              G  NTG FN G++NTG  NPG+YN+G  N G+ NTG  N G+YNTG+ N GDYNTG+AN
Sbjct  805   VGVANTGLFNIGNLNTGIGNPGNYNSGAHNVGSTNTGGANQGDYNTGWLNLGDYNTGLAN  864

Query  387   TGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQL-FSMPIHQVMVMPGS  445
              GNVNTGA I+GNY NG+LWR DY+   G   A+ +  +PI   L  S+PI   +     
Sbjct  865   VGNVNTGALISGNYDNGILWRSDYRAQGGFSYAIGL--VPITTSLNLSVPIDIPISATVG  922

Query  446   VMTIPGMRLPFTSIVPFVVY---YGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGG  502
                I G  +P   I  + V     GP   P  T+  PT+ I VGG  +    +     G 
Sbjct  923   NTVIEGFTIPEIPIGAYGVVSGNIGPETFPTITIVGPTIDIGVGGTQSVFTPSFVVDTGL  982

Query  503   VSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFG  562
             V   ++ +P+ PG GNST+  SSGFFN+G G+ASGFGN GG  SGF N A+ + G SGF 
Sbjct  983   VQAIVLDLPSGPGVGNSTSVESSGFFNSGDGSASGFGNGGGSNSGFLNFATDSLGNSGFK  1042

Query  563   NVGALGSGVANVGNTISGLYNTSTSNLATPA-------------------------FNSG  597
             N G L SG+AN+GN++SG++NTS  +L T A                         FN G
Sbjct  1043  NYGTLESGIANLGNSVSGVFNTSALDLLTAANVSGVSNFGSNLSGFFLAGDSADRIFNVG  1102

Query  598   LLHH---SVGTMTL---NFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLG  651
             + +    ++G+  L   NFGL NVG  N G  N G  N+G AN+GD N GFGN+G +N G
Sbjct  1103  VANDGSFNIGSANLGDYNFGLGNVGNTNFGPGNLGSTNIGGANIGDTNFGFGNIGANNFG  1162

Query  652   FAHAGS------YNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSL  705
             F ++G+      +NIGF NTGSNN+G  NTGD NIGF N G++N GIGL G G  GFG  
Sbjct  1163  FGNSGASLTDGNHNIGFGNTGSNNIGIGNTGDGNIGFGNTGNDNTGIGLNGDGLQGFGGW  1222

Query  706   NSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLF  765
             NSGS          GNIG+FNSG+ N GIGN+GTGN GIGNSG+ N GIGN+G  NTGLF
Sbjct  1223  NSGS----------GNIGVFNSGTDNVGIGNSGTGNSGIGNSGSYNTGIGNSGLANTGLF  1272

Query  766   NSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
             NSG  NTG  N GSYNTG+ N G  NTG FN G  NTG  N GDL 
Sbjct  1273  NSGSFNTGIGNVGSYNTGTFNVGDHNTGNFNTGQSNTGSLNVGDLN  1318


 Score =  342 bits (876),  Expect = 3e-91, Method: Compositional matrix adjust.
 Identities = 301/749 (41%), Positives = 381/749 (51%), Gaps = 116/749 (15%)

Query  190   AGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGG--  247
             AG  +   +NLG  N+G  NVG  NVG FN G  N+G  N GF N+G++N G  N G   
Sbjct  1590  AGAANTGNYNLGFGNIGDGNVGAANVGNFNFGGANIGDTNFGFGNIGNNNFGFGNSGASL  1649

Query  248   ----HNIGFANTGSNN----------VGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIG  293
                 HNIGF NTGSNN          +GFGNTG  N+GIGL+G+G  GFG+ N+GS N+G
Sbjct  1650  TNGNHNIGFGNTGSNNFGFGNTGDGNIGFGNTGDGNIGIGLSGDGLRGFGALNTGSGNVG  1709

Query  294   LFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTG  353
             LFNSG+ N+GLFNSG+ N GIGNSG GN GL N+G+ +TG FN G VNTG  N G +NTG
Sbjct  1710  LFNSGTNNIGLFNSGSDNIGIGNSGIGNAGLFNSGNYDTGMFNAGIVNTGIGNAGDFNTG  1769

Query  354   NFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGL  413
              FN G+ NTG+ N+G+YNTG FN+G+Y+TG ANTG+V+TG FI+GNYSNG+L RGDYQGL
Sbjct  1770  TFNAGDANTGNANSGSYNTGGFNSGNYDTGWANTGDVDTGIFISGNYSNGILARGDYQGL  1829

Query  414   IGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQ  473
             +G  +  +I A P                 G      G    F +    V  YG +   Q
Sbjct  1830  VGVPL-FDIAAAP------GFGNTTTSYSSGFFNNGAGSGSGFFNSGTDVSGYGNLGAVQ  1882

Query  474   STLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAG  533
             S L                  +++G+    S+         G GN+  + +  F ++  G
Sbjct  1883  SGL-------------ANYGNSVSGLFNTSSLDTATAAYVSGVGNAGANLAGLFRDSAGG  1929

Query  534   TA--SGFGNFGGGASGFWNLASATSGLSGFG--NVGALGSGVANVGNTISGLYNTSTSNL  589
             T    GF N      G  NL +A  G    G  NVG +  G AN+G+      N    NL
Sbjct  1930  TTLNVGFANL-----GVLNLGAANVGDYNVGTANVGGINFGGANIGD-----LNFGAGNL  1979

Query  590   ATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDN  649
              +  F  G L  +      NFG  N G             V LAN G++N GFGN G +N
Sbjct  1980  GSTNFGFGNLGSN------NFGFGNSG-------------VSLAN-GNHNFGFGNTGSNN  2019

Query  650   LGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGS  709
                        GF NTG  N+GF NTGD NI          GIGL G G  GF +LNSG+
Sbjct  2020  F----------GFGNTGDGNIGFGNTGDGNI----------GIGLNGDGLRGFEALNSGT  2059

Query  710   HNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGD  769
              N+GLFNSG GN+          GIGN+GTGNWGIGNSG  N G+GN G+ NTG+FNSG 
Sbjct  2060  DNVGLFNSGTGNV----------GIGNSGTGNWGIGNSGNYNTGVGNTGAANTGMFNSGI  2109

Query  770   LNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ---------HRHGEHRQY  820
              NTG  N GSYNTG++N G +NTG FN G  NTGYFN GD           +  G +   
Sbjct  2110  ANTGVANAGSYNTGNLNAGDINTGSFNTGVSNTGYFNVGDTNTGIANLGDINTGGFNSGS  2169

Query  821   QHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYPDS-HTDHRQLHGHRI  879
              +  F LR  +        Q G +   +      + D     + P S       +H   I
Sbjct  2170  MNNGFLLRGDEL------GQLGFNYTLNIPTLPVDLDIYANFQTPISLDVGGTTIHSFDI  2223

Query  880   QRARSSTEHSRHCYFFRTRRYRPLHRPSD  908
                  S ++         +   P     D
Sbjct  2224  SAFTISGKYGYSYKVLGIKFNYPFKYSFD  2252


 Score =  280 bits (715),  Expect = 1e-72, Method: Compositional matrix adjust.
 Identities = 214/487 (44%), Positives = 273/487 (57%), Gaps = 37/487 (7%)

Query  128   FNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAA  187
             FN  ++    AAY        A + G    ++   +  + F      L  L+    +   
Sbjct  1896  FNTSSLDTATAAYVSGVGNAGANLAGLFRDSAGGTTLNVGF----ANLGVLNLGAANVGD  1951

Query  188   AAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLG------SDNLG  241
                G  +  G N G AN+G  N G GN+G  N GFGNLGS N GF N G      + N G
Sbjct  1952  YNVGTANVGGINFGGANIGDLNFGAGNLGSTNFGFGNLGSNNFGFGNSGVSLANGNHNFG  2011

Query  242   LANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGN  301
               N G +N GF NTG  N+GFGNTG  N+GIGL G+G  GF + NSG+ N+GLFNSG+GN
Sbjct  2012  FGNTGSNNFGFGNTGDGNIGFGNTGDGNIGIGLNGDGLRGFEALNSGTDNVGLFNSGTGN  2071

Query  302   VGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYN  361
             VG+ NSGTGN+GIGNSG  N G+GNTG+ NTG FN+G  NTG  N GSYNTGN N G+ N
Sbjct  2072  VGIGNSGTGNWGIGNSGNYNTGVGNTGAANTGMFNSGIANTGVANAGSYNTGNLNAGDIN  2131

Query  362   TGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALE  421
             TGSFN G  NTGYFN GD NTG+AN G++NTG F +G+ +NG L RGD  G +G +  L 
Sbjct  2132  TGSFNTGVSNTGYFNVGDTNTGIANLGDINTGGFNSGSMNNGFLLRGDELGQLGFNYTLN  2191

Query  422   IPAIPINAQL---FSMPIH------QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVE--  470
             IP +P++  +   F  PI        +     S  TI G +  ++  V  + +  P +  
Sbjct  2192  IPTLPVDLDIYANFQTPISLDVGGTTIHSFDISAFTISG-KYGYSYKVLGIKFNYPFKYS  2250

Query  471   LPQSTLTLPTVTI-------TVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSP  523
                  +T+P++ I       TVG P      N  G  G ++I +   P APGF N T + 
Sbjct  2251  FDIPAITIPSIQIGGSSQNFTVGPPALNTTINFDG--GPLNIAVDMDP-APGFFNFTNND  2307

Query  524   SSGFFNAGAGTASGFGNFGGGASGFWN-----LASATSGLSGFGNVGALGSGVANVGNTI  578
             SSGFFN+G G  SG GN GG  SGF N       S +S  SG  N G L SG+ NVGNT+
Sbjct  2308  SSGFFNSGKGFTSGLGNIGGYDSGFLNGSMDPFGSGSSQTSGVYNFGELQSGLVNVGNTV  2367

Query  579   SGLYNTS  585
             SG +NTS
Sbjct  2368  SGFFNTS  2374


 Score =  175 bits (443),  Expect = 5e-41, Method: Compositional matrix adjust.
 Identities = 114/199 (58%), Positives = 138/199 (70%), Gaps = 18/199 (9%)

Query  638  YNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGS  697
            YN+G+GNLGG N GF +AGS N GFANTGSNN GFANTG  N+GF N GSNNIGIGL+G 
Sbjct  263  YNLGWGNLGGANQGFGNAGSNNQGFANTGSNNQGFANTGSFNVGFGNTGSNNIGIGLSGD  322

Query  698  GQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNA  757
            G+IGFGSLNSGS          GNIGLFNSG+ N G  N+GTGN+G+ NSG+ N G GN+
Sbjct  323  GKIGFGSLNSGS----------GNIGLFNSGTNNIGFFNSGTGNFGVLNSGSYNTGFGNS  372

Query  758  GSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ------  811
            G  +TG+FN G+ NTG  N G++NTGS N G+ NTGGFN GN NTG+ NTGD+       
Sbjct  373  GEASTGVFNPGNANTGWANTGNHNTGSFNAGNTNTGGFNPGNLNTGWANTGDVDTGAFIS  432

Query  812  --HRHGEHRQYQHRRFHLR  828
              + +G   Q  +R   + 
Sbjct  433  GSYSNGLFWQDDYRLLGID  451


>gi|298523777|ref|ZP_07011186.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298493571|gb|EFI28865.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
Length=1147

 Score =  605 bits (1560),  Expect = 1e-170, Method: Compositional matrix adjust.
 Identities = 414/737 (57%), Positives = 478/737 (65%), Gaps = 108/737 (14%)

Query  168   FTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGS  227
             F   L  +AGL +    A             N+GLAN+G +N G GN G+FNVGF N+G+
Sbjct  308   FGSGLANIAGLLQG--GAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGN  365

Query  228   YNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNS  287
             +N+G ANLG+ ++G AN G ++IG ANTGS N+GF NTGS N+GIGLTG  QIGFGSFNS
Sbjct  366   HNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTVQIGFGSFNS  425

Query  288   GSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFG----------LGNTGSTNTGWFN-  336
             GSHNIGLFNSG GNVG FNSGTGN GIGN+GT NFG          LGNTGSTNTG FN 
Sbjct  426   GSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNP  485

Query  337   ---------TGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                      TG +NTG FN GS NTG+FN G++NTGSFN+G+YNTGYFN GDYNTGVANT
Sbjct  486   GNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANT  545

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIH-----QVMVM  442
             GNVNTGAFI+GNYSNG  WRGDYQGLIG    + IP IP    L S+PI       V+  
Sbjct  546   GNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDL-SVPIDIPITGTVVAT  604

Query  443   PGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDG------NL  496
               +  TIPG ++         V  GP  +  + +  P +TI V      ID       ++
Sbjct  605   TPNSFTIPGFQIR--------VLLGPAAVLVNEMIGP-ITIDVN-QVIAIDSPIQQTISM  654

Query  497   TGMVGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNF-----------GGG  544
              G  G   IP+ I I   PGFGNSTT PSSGFF+ GAG  SGFGNF           G G
Sbjct  655   VGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFAAGNMSGSGNFGAG  714

Query  545   ASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG-------  597
              SGF+N      G SG  N GAL SG+AN+GNTISG+YNTST +LATPAF SG       
Sbjct  715   NSGFFNAGGL--GNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGAN  772

Query  598   ---LLHHSVGTMTLNFGLAN----------------------------------------  614
                L   + G +TLNFG+AN                                        
Sbjct  773   LAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVN  832

Query  615   VGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFAN  674
             +GGNN+G AN GIF++GLANLG YNIG  NLG DNLGF +AGSYNIGFAN GS+NLGFAN
Sbjct  833   IGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFAN  892

Query  675   TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGI  734
             TG  NIGFAN G+NNIG+GLTG+GQIG GSLNSGS+NIGLFNSG GNIG FNSG+GN GI
Sbjct  893   TGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGI  952

Query  735   GNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGG  794
              N GTGN+G+ NSG  N GIGNAGSTNTG+FN GDLNTGS NPGS+NTG  N GS NTG 
Sbjct  953   FNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGY  1012

Query  795   FNAGNYNTGYFNTGDLQ  811
              N G+YNTG  NTGD+ 
Sbjct  1013  LNTGDYNTGVANTGDVD  1029


 Score =  547 bits (1409),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 340/550 (62%), Positives = 405/550 (74%), Gaps = 33/550 (6%)

Query  294  LFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTG  353
            +FNSG GN+G FNSGTGNFGIGN+GTGNFG+GN+GST+TG FN+GD NTGGFNPG++NTG
Sbjct  1    MFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTG  60

Query  354  NFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGL  413
            NFNTG++NTG FNAGN NTG+FNTG+YNTG+ANTG+V+TGAFI+GNYSNG+LWRGDYQGL
Sbjct  61   NFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGL  120

Query  414  IGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYY-------  466
            IG   AL IP IP +  + ++PI   +    + + +    +P      F   +       
Sbjct  121  IGYSYALTIPEIPAHLDV-NIPIDIPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPD  179

Query  467  -GPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
             GP+ +P   L++PT  I VGGPTT I+ + T  +G ++IP+I IPAAPG GNSTTSPSS
Sbjct  180  IGPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSS  239

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GFFN GAGTASGFGN GG  SG WNLASA SG+SG  NVGALGSGVANVGNTISG+YNTS
Sbjct  240  GFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVANVGNTISGIYNTS  299

Query  586  TSNLATPAFNS------GLLHHSVGTMT--------LNFGLANVGGNNVGGANAGIFNVG  631
              +L TPAF S      GLL    GT          LN GLAN+GG+N G  N GIFNVG
Sbjct  300  PLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVG  359

Query  632  LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             AN+G++NIG  NLG  ++GFA++G+Y+IG ANTGS N+GFANT          GS NIG
Sbjct  360  FANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANT----------GSGNIG  409

Query  692  IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGN  751
            IGLTG+ QIGFGS NSGSHNIGLFNSGDGN+G FNSG+GN GIGN GT N+GI NSG+ N
Sbjct  410  IGLTGTVQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFN  469

Query  752  FGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
             G+GN GSTNTGLFN G++NTG  N GS NTGS NTGS NTG FN G++NTG FN+GD  
Sbjct  470  TGLGNTGSTNTGLFNPGNVNTGVGNTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYN  529

Query  812  HRHGEHRQYQ  821
              +     Y 
Sbjct  530  TGYFNAGDYN  539


 Score =  264 bits (674),  Expect = 6e-68, Method: Compositional matrix adjust.
 Identities = 157/239 (66%), Positives = 180/239 (76%), Gaps = 11/239 (4%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGL----------ANLGG  247
              N G  N+G NN+G  N G+F++G  NLGSYN+G ANLG DNLG           AN G 
Sbjct  826   LNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGS  885

Query  248   HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
              N+GFANTGS N+GF NTG+NN+G+GLTGNGQIG GS NSGS+NIGLFNSGSGN+G FNS
Sbjct  886   DNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNS  945

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN GI N+GTGNFGL N+G  NTG  N G  NTG FNPG  NTG+FN G++NTG FN 
Sbjct  946   GTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNP  1005

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP  426
             G+ NTGY NTGDYNTGVANTG+V+TGAFI G+YSNG L  GDYQGLIG  + L IP  P
Sbjct  1006  GSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPL-LGIPVTP  1063


 Score = 85.1 bits (209),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 56/107 (53%), Positives = 69/107 (65%), Gaps = 16/107 (14%)

Query  492   IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNL  551
             + G+  G++G   +PL+ IP  PG+ N T  PSSGFFN+GAG+ SGF N G         
Sbjct  1044  VSGDYQGLIG---LPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSG---------  1091

Query  552   ASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
                 +GLSG+ N GALGSGVANVGNTISG  N S  +LATP F SG+
Sbjct  1092  ----AGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGI  1134


 Score = 53.5 bits (127),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 75/182 (42%), Positives = 95/182 (53%), Gaps = 18/182 (9%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNI  250
             G  ++ GFN G+ N G+ N G  N G  N G  N GS+N G  N GS N G  N G +N 
Sbjct  961   GLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNT  1020

Query  251   GFANTGSNNVGFGNTGSNNVGIGLTGN--GQIGF---------GSFN-SGSHNIGLFNSG  298
             G ANTG  + G   TGS + G  ++G+  G IG          G FN +G  + G FNSG
Sbjct  1021  GVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSG  1080

Query  299   SGNV-GLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG--DVNTGGFNPGSYNTGNF  355
             +G+V G  NSG G  G  N+G    G+ N G+T +GW N    D+ T GF  G    GNF
Sbjct  1081  AGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSG---IGNF  1137

Query  356   NT  357
              T
Sbjct  1138  GT  1139


 Score = 52.4 bits (124),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 76/199 (39%), Positives = 99/199 (50%), Gaps = 22/199 (11%)

Query  221  GFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQI  280
            GFGN+G    G  NL S   G++       G  N G+   G  N G+   GI  T    +
Sbjct  251  GFGNVGGNTSGLWNLASAASGVS-------GLLNVGALGSGVANVGNTISGIYNTSPLDL  303

Query  281  GFGSFNSGSHNI-GLFNSGSGNVGLFNSGTGNFGIG--NSGTGNFGLGNTGSTNTGWFNT  337
            G  +F SG  NI GL   G+G   L  +G GN  +G  N G  NFG+GNTG      FN 
Sbjct  304  GTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTG-----IFNV  358

Query  338  GDVNTGGFNPGSYNTGNF-----NTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNT  392
            G  N G  N G  N GN+     N+GNY+ G  N G+ N G+ NTG  N G+  TG V  
Sbjct  359  GFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTVQI  418

Query  393  --GAFIAGNYSNGVLWRGD  409
              G+F +G+++ G+   GD
Sbjct  419  GFGSFNSGSHNIGLFNSGD  437


>gi|240171835|ref|ZP_04750494.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=717

 Score =  568 bits (1464),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 386/737 (53%), Positives = 475/737 (65%), Gaps = 78/737 (10%)

Query  8    PEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGPAAVAMAR  67
            PE+NS R++ GAGS P LAA+ AW GLA EL  AA+ F S TSGLA   W+GPAA AM  
Sbjct  4    PEINSARLFTGAGSAPALAASTAWAGLAAELRSAAAAFLSATSGLAGKFWQGPAATAMTA  63

Query  68   AVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLG  127
            A A Y+GWL +A   AEQAA     A   FE AR+ TVHP +VAANR  LVSLV SNL G
Sbjct  64   AAASYVGWLSAAGVHAEQAAELGEAAAQAFEVARSVTVHPGLVAANRDRLVSLVRSNLFG  123

Query  128  FNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAA  187
             N PA+AA EA YE+MWA+DVAAM+ YHAGASA  SAL PF++ +  LAGLS RL    A
Sbjct  124  QNTPAVAAAEAEYEQMWARDVAAMLDYHAGASAVASALTPFSRHIPDLAGLSGRLAGLDA  183

Query  188  AA-----------------------------AGPPSAAGFNLGLANVGANNVGNGNVGVF  218
            A                               G  +   FNLG  N+G+ NVG+GN+G F
Sbjct  184  ANVNAATAAVIGSANSTINFNLGFANIGRGNVGAANEGNFNLGFGNIGSGNVGSGNIGSF  243

Query  219  NVGFGNLGSYNLGFANLGSDNLGLANLG----------GHNIGFANTGSNNVGFGNTGSN  268
            N G GN+GSYN+G  NLG+ N+GL NLG            N+GFAN GSNN+GF NTG+N
Sbjct  244  NAGSGNVGSYNIGPGNLGNYNVGLGNLGNSSLGVGNAGSFNVGFANAGSNNIGFANTGNN  303

Query  269  NVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTG  328
            N+GIGLTG+G++GFG  NSGS NIGLFNSG+GN+G FNSGTGNFG+GNSG+ + G+GN G
Sbjct  304  NIGIGLTGDGRVGFGGLNSGSDNIGLFNSGTGNIGFFNSGTGNFGVGNSGSYSTGIGNAG  363

Query  329  STNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG  388
             TNTG FNTG VNTG  N G+YN+G FN G+ NTG FN G+YNTGY N GDYNTG  NTG
Sbjct  364  GTNTGLFNTGLVNTGFGNAGNYNSGGFNAGSTNTGGFNTGDYNTGYVNVGDYNTGAGNTG  423

Query  389  NVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQ---LFSMPIHQVMVMPGS  445
            +VNTGAFI+GNYSNG+ WRGDYQG  G   ++ IPAIP+N Q      +P  +V + P  
Sbjct  424  DVNTGAFISGNYSNGLFWRGDYQG-TGLSYSITIPAIPVNIQESYTLDVPF-EVDIGP--  479

Query  446  VMTIPGMRLPFTSIVPF---VVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGG  502
              TIP   +P  ++      ++  GP+  P   +T P ++  +G   TT+  N TG +G 
Sbjct  480  -QTIPSFVIPEQAVTVLGLNLLSVGPITFPDIHITGPVLSFEIG--PTTLRLNATGAIGP  536

Query  503  VSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFG  562
            + IP+I IPA PGFGNST+SPSSGFFN+G G+ SGFGNFG  +SG+ NL S +SG+    
Sbjct  537  IKIPIIDIPATPGFGNSTSSPSSGFFNSGTGSVSGFGNFGVNSSGWVNLGSGSSGVQ---  593

Query  563  NVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG----------LLHHSVGTMTLNFGL  612
            NVGAL SG+AN+G+T+SG +NT    LA PA  SG          LL       + N G 
Sbjct  594  NVGALQSGLANLGDTVSGAFNTG---LAIPARVSGIGNVGSDLAGLLRGFGSAASFNLGF  650

Query  613  ANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGF  672
             N+G  N+G  N G FN G  N+GDYNIG GNLG          +YN+G  N G++++G 
Sbjct  651  GNLGYANIGSGNVGSFNAGSGNIGDYNIGPGNLG----------NYNVGLGNLGNSSVGI  700

Query  673  ANTGDNNIGFANIGSNN  689
             N GD N+G AN GSNN
Sbjct  701  GNAGDYNVGIANAGSNN  717


 Score =  202 bits (513),  Expect = 3e-49, Method: Compositional matrix adjust.
 Identities = 127/218 (59%), Positives = 147/218 (68%), Gaps = 10/218 (4%)

Query  608  LNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS  667
             N G  N+G  NVG  N G FN G  N+G YNIG GNLG  N+G  + G+ ++G  N GS
Sbjct  223  FNLGFGNIGSGNVGSGNIGSFNAGSGNVGSYNIGPGNLGNYNVGLGNLGNSSLGVGNAGS  282

Query  668  NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNS  727
             N+GFAN G NNIGFAN G+NNIGIGLTG G++GFG LNSGS NIGLFNSG GNIG FNS
Sbjct  283  FNVGFANAGSNNIGFANTGNNNIGIGLTGDGRVGFGGLNSGSDNIGLFNSGTGNIGFFNS  342

Query  728  GSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNT  787
            G+GNF          G+GNSG+ + GIGNAG TNTGLFN+G +NTG  N G+YN+G  N 
Sbjct  343  GTGNF----------GVGNSGSYSTGIGNAGGTNTGLFNTGLVNTGFGNAGNYNSGGFNA  392

Query  788  GSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRF  825
            GS NTGGFN G+YNTGY N GD     G         F
Sbjct  393  GSTNTGGFNTGDYNTGYVNVGDYNTGAGNTGDVNTGAF  430


 Score =  112 bits (280),  Expect = 3e-22, Method: Compositional matrix adjust.
 Identities = 91/208 (44%), Positives = 119/208 (58%), Gaps = 20/208 (9%)

Query  619  NVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDN  678
            N+G AN G  NVG AN G++N+GFGN+G  N+G  + GS+N G  N GS N+G  N G+ 
Sbjct  204  NLGFANIGRGNVGAANEGNFNLGFGNIGSGNVGSGNIGSFNAGSGNVGSYNIGPGNLGNY  263

Query  679  NIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAG  738
            N+G  N+G++++G+G            N+GS N+G  N+G  NIG  N+G+ N GIG  G
Sbjct  264  NVGLGNLGNSSLGVG------------NAGSFNVGFANAGSNNIGFANTGNNNIGIGLTG  311

Query  739  TGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAG  798
             G  G        FG  N+GS N GLFNSG  N G  N G+ N G  N+GS +TG  NAG
Sbjct  312  DGRVG--------FGGLNSGSDNIGLFNSGTGNIGFFNSGTGNFGVGNSGSYSTGIGNAG  363

Query  799  NYNTGYFNTGDLQHRHGEHRQYQHRRFH  826
              NTG FNTG +    G    Y    F+
Sbjct  364  GTNTGLFNTGLVNTGFGNAGNYNSGGFN  391


 Score = 58.9 bits (141),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 70/177 (40%), Positives = 92/177 (52%), Gaps = 22/177 (12%)

Query  617  GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTG  676
            GN+    ++G FN G  ++     GFGN G ++ G+ + GS + G  N G+   G AN G
Sbjct  551  GNSTSSPSSGFFNSGTGSVS----GFGNFGVNSSGWVNLGSGSSGVQNVGALQSGLANLG  606

Query  677  DN-----NIGFANIGSNNIGIGLTGSGQIGF-------GSLNSGSHNIGLFNSGDGNIGL  724
            D      N G A I +   GIG  GS   G         S N G  N+G  N G GN+G 
Sbjct  607  DTVSGAFNTGLA-IPARVSGIGNVGSDLAGLLRGFGSAASFNLGFGNLGYANIGSGNVGS  665

Query  725  FNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYN  781
            FN+GSGN G  N G GN  +GN    N G+GN G+++ G+ N+GD N G  N GS N
Sbjct  666  FNAGSGNIGDYNIGPGN--LGNY---NVGLGNLGNSSVGIGNAGDYNVGIANAGSNN  717


 Score = 56.6 bits (135),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 66/156 (43%), Positives = 86/156 (56%), Gaps = 9/156 (5%)

Query  661  GFANTGSNNL-GFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLN---SGSHNIGLF-  715
            GF N+G+ ++ GF N G N+ G+ N+GS + G+   G+ Q G  +L    SG+ N GL  
Sbjct  560  GFFNSGTGSVSGFGNFGVNSSGWVNLGSGSSGVQNVGALQSGLANLGDTVSGAFNTGLAI  619

Query  716  ---NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNT  772
                SG GN+G   +G    G G+A + N G GN G  N G GN GS N G  N GD N 
Sbjct  620  PARVSGIGNVGSDLAGLLR-GFGSAASFNLGFGNLGYANIGSGNVGSFNAGSGNIGDYNI  678

Query  773  GSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
            G  N G+YN G  N G+ + G  NAG+YN G  N G
Sbjct  679  GPGNLGNYNVGLGNLGNSSVGIGNAGDYNVGIANAG  714


 Score = 49.7 bits (117),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 64/164 (40%), Positives = 81/164 (50%), Gaps = 22/164 (13%)

Query  661  GFAN-TGSNNLGFANTGDNNI-GFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSG  718
            GF N T S + GF N+G  ++ GF N G N+       SG +  GS +SG  N+G   SG
Sbjct  549  GFGNSTSSPSSGFFNSGTGSVSGFGNFGVNS-------SGWVNLGSGSSGVQNVGALQSG  601

Query  719  DGNIGLFNSGSGNFG---------IGNAGTGNWGI----GNSGAGNFGIGNAGSTNTGLF  765
              N+G   SG+ N G         IGN G+   G+    G++ + N G GN G  N G  
Sbjct  602  LANLGDTVSGAFNTGLAIPARVSGIGNVGSDLAGLLRGFGSAASFNLGFGNLGYANIGSG  661

Query  766  NSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            N G  N GS N G YN G  N G+ N G  N GN + G  N GD
Sbjct  662  NVGSFNAGSGNIGDYNIGPGNLGNYNVGLGNLGNSSVGIGNAGD  705


>gi|31794527|ref|NP_857020.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|31620123|emb|CAD95503.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
Length=1338

 Score =  567 bits (1461),  Expect = 4e-159, Method: Compositional matrix adjust.
 Identities = 472/1008 (47%), Positives = 554/1008 (55%), Gaps = 236/1008 (23%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M FVV  PE+NSL +Y GAG GP+LAAAAAWD LA EL  AA+ FGSVTSGL    W+GP
Sbjct  1    MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            ++VAMA A APY GWL +A A AE AA QAR  V  FEAA AATV P ++AANR+ LVSL
Sbjct  61   SSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
              SNL G N PAIAA E  YE MWAQDVAAM+GYH GASAA  AL PF   L  LA  +E
Sbjct  121  ALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSY------------  228
               S A            NLGLANVG  N G+GNVG +NVG GN+GSY            
Sbjct  181  PAKSLAV-----------NLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNV  229

Query  229  --------NLGFAN-------LGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273
                    N+G AN       +G  N+G  N G +N G AN G  N+GF NTGS N GIG
Sbjct  230  GLGNVGFGNVGLANSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIG  289

Query  274  LTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTG  333
            LTG+   GFG FN+GS N+GLFNSG+GNVG FNSGTGN+G+ NSG+ N G+GN+G  +TG
Sbjct  290  LTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTG  349

Query  334  WFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTG  393
             FN G  NTG  N GSYNTG+FN G  NTG FN G+ NTG+ NTGD NTGVAN+G+VNTG
Sbjct  350  LFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTG  409

Query  394  AFIAGNYSNGVLWRGDYQGLIG-------------ADIALE-------IPAIPINA----  429
            AFI+GNYSNGVLWRGDYQGL+G              D+ L        IPAI I A    
Sbjct  410  AFISGNYSNGVLWRGDYQGLLGFSYRPAVLPQTPFLDLTLTGGLGSVVIPAIDIPAIRPE  469

Query  430  ----------QLFSMPIHQVMVMPGSV------MTIPGMRLPFTSIVPFVVYY-------  466
                       + S+PI Q+ +   +V      +T+P + +P    VP  + Y       
Sbjct  470  FSANVAIDSFTVPSIPIPQIDLAATTVSVGLGPITVPHLDIPR---VPVTLNYLFGSQPG  526

Query  467  GPVEL---------------------------PQSTLTLPTVTITVGGPTTTIDG-----  494
            GP+++                            Q T+T     +    P  TID      
Sbjct  527  GPLKIGPITGLFNTPIGLTPLALSQIVIGASSSQGTITAFLANLPFSTPVVTIDEIPLLA  586

Query  495  --------------------------NLTGMVGGVSIP----------------------  506
                                      NL+G  G V+IP                      
Sbjct  587  SITGHSEPVDIFPGGLTIPAMNPLSINLSGGTGAVTIPAITIGEIPFDLVAHSTLGPVHI  646

Query  507  LIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASAT--SGLSGFGNV  564
            LI +PA PGFGN+T +PSSGFFN+GAG  SGFGN G   SG WN A +    G SG  N 
Sbjct  647  LIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNA  706

Query  565  GALGSGVANVGNTISGLYNTSTSNLATPAFNSGL----------------LHHSVGTMTL  608
            G L SGV N G+ +SGL+NTS   L  PA  SGL                LH     + L
Sbjct  707  GTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQG---LVL  763

Query  609  NFGLANVGGNNVGGANAGIFNVGLANLGDYNIG-------------------------FG  643
            NFGLA+VG          + NVGL N+GD+N+G                         +G
Sbjct  764  NFGLADVG----------LGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWG  813

Query  644  NLGGDNLGFAH--AGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIG  701
            N G  N G      G  NIGF N GS N G AN G  NIGFAN GS N GIGLTG    G
Sbjct  814  NFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTG  873

Query  702  FGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTN  761
            FG  N+GS N+GLFNSG GN+G FNS          GTGNWG+ NSG+ N GIGN+G  +
Sbjct  874  FGGFNTGSGNVGLFNSGTGNVGFFNS----------GTGNWGVFNSGSYNTGIGNSGIAS  923

Query  762  TGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            TGLFN+G  NTG +N GSYNTGS N G  NTGGFN G+ NTG+ NTGD
Sbjct  924  TGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGD  971


 Score =  229 bits (585),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 169/351 (49%), Positives = 199/351 (57%), Gaps = 48/351 (13%)

Query  157   GASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVG  216
             GA A VS L    QQL  L      L S  A   G       N GLA+VG  NVG GNVG
Sbjct  732   GAPALVSGLGSVGQQLSGL------LASGTALHQG----LVLNFGLADVGLGNVGLGNVG  781

Query  217   VFNVG-------------------------FGNLGSYNLGFAN--LGSDNLGLANLGGHN  249
              FN+G                         +GN G  N G     +G  N+G  N G +N
Sbjct  782   DFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYN  841

Query  250   IGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGT  309
              G AN G  N+GF NTGS N GIGLTG+   GFG FN+GS N+GLFNSG+GNVG FNSGT
Sbjct  842   FGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGT  901

Query  310   GNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGN  369
             GN+G+ NSG+ N G+GN+G  +TG FN G  NTG  N GSYNTG+FN G  NTG FN G+
Sbjct  902   GNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGS  961

Query  370   YNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIG----ADIALEIPAI  425
              NTG+ NTGD NTGVAN+G+VNTGAFI+GNYSNG  WRGDYQGL+G    + I  E    
Sbjct  962   VNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVA  1021

Query  426   PINAQ----LFSMPIHQVMVMPGSVMT---IPGMRLPFTSIVPFVVYYGPV  469
              I+A        +P  Q   +P  +     I G  +P  SI P  V   PV
Sbjct  1022  NIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPV  1072


 Score = 70.1 bits (170),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 66/171 (39%), Positives = 84/171 (50%), Gaps = 20/171 (11%)

Query  447   MTIPGMRLPFTSI---VPFVVYYGPVELPQSTLTLPTVTITVGGPT--------TTIDG-  494
             +TIPG  +P   I   +P  V  GP   P+ T+    + + + G T         TID  
Sbjct  1152  ITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRI  1211

Query  495   ----NLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTA-SGFGNFGGGASGFW  549
                 ++  ++G ++  L+ IP  PGFGN+T  PSSGFFN G G   SGF N G G SG  
Sbjct  1212  PVVLDVNALLGPINAGLV-IPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVL  1270

Query  550   NLAS--ATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
             N  S       SGF N G   SG+ N G  ISG+YNT    L T A  SG 
Sbjct  1271  NAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGF  1321


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 69/171 (41%), Positives = 81/171 (48%), Gaps = 22/171 (12%)

Query  515  GFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGF----GNVGALGSG  570
            GFGN+  S + G  N G G   GF N G G  G        +G  GF    GNVG   SG
Sbjct  833  GFGNAG-SYNFGLANMGVGNI-GFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSG  890

Query  571  VANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNV  630
              NVG      +N+ T N     FNSG         + N G+ N G  + G  NAG FN 
Sbjct  891  TGNVG-----FFNSGTGNWG--VFNSG---------SYNTGIGNSGIASTGLFNAGGFNT  934

Query  631  GLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIG  681
            G+ N G YN G  N G  N G  + GS N G+ NTG  N G AN+GD N G
Sbjct  935  GVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTG  985


>gi|240173399|ref|ZP_04752057.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=1232

 Score =  563 bits (1452),  Expect = 4e-158, Method: Compositional matrix adjust.
 Identities = 375/689 (55%), Positives = 460/689 (67%), Gaps = 79/689 (11%)

Query  198  FNLGLANVGANNVGNGNVGVFNVGFG----------NLGSYNLGFANLGSDNLGLANLGG  247
             N+G ANVG +NVG  N+G  NVGFG          NLG+ N G AN G DN G AN G 
Sbjct  230  LNVGSANVGNHNVGGANIGNVNVGFGSHGLHNIGSANLGNDNFGPANFGDDNRGFANAGN  289

Query  248  HNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
             NIG ANTG  N+G  NTGSNN+GIGLTGNG++G G+ NSGS N GLFNSG+ N GLFNS
Sbjct  290  ANIGLANTGDGNIGLANTGSNNIGIGLTGNGKVGIGALNSGSGNTGLFNSGTDNAGLFNS  349

Query  308  GTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
            GTGN GI NSGTGN+G+GN+GSTNTG+ N+G VNTG +N G+ N+G  NTG+YN+GSFNA
Sbjct  350  GTGNVGIANSGTGNWGIGNSGSTNTGFGNSGMVNTGLWNAGNVNSGIGNTGDYNSGSFNA  409

Query  368  GN----------YNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD  417
            G+          YNTGY NTG YNTG+AN+GNV+TG F +G+Y NG+LWRGDYQGL+G +
Sbjct  410  GSFNTAGFNPGSYNTGYSNTGSYNTGLANSGNVDTGLFNSGSYDNGILWRGDYQGLLGYN  469

Query  418  IALEIP--AIPINAQLFSMPIHQVMVMPGSVMTIPGMRLP-FTSIVPFV-------VYYG  467
              + IP  AIP+N  +  +PI   +     ++TI G  +P +T+ +  +       +  G
Sbjct  470  YTIYIPDTAIPVNLDV-EIPIDIPISATFGILTIEGFTIPKYTADITVLDAGTTQAISVG  528

Query  468  PVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGF  527
            P+ +    ++LP +  T+GGPTT ID   TG +G ++IP+I IP APGFGNST  PSSGF
Sbjct  529  PLTVSDIVVSLPPLATTIGGPTTAIDITGTGGIGPIAIPVIDIPPAPGFGNSTVLPSSGF  588

Query  528  FNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTS  587
            FN+GAG++SG  N G   SGF+N AS  SG+SG+ NVG L SG+AN GNT+SGL NTST 
Sbjct  589  FNSGAGSSSGLANVGPNNSGFFN-ASGNSGISGYKNVGDLVSGMANFGNTVSGLLNTSTL  647

Query  588  NLATPAFNSGLL-----------HHSVGTM------TLNFGLANVGGNNVGGANAGIFNV  630
            +L TPA  SG+            + +V  +      +LN G  NVG  NVG  N G  NV
Sbjct  648  DLGTPANVSGVANVGSDVAGFFGNSAVSNLGFANDGSLNVGSGNVGNLNVGSGNVGTHNV  707

Query  631  GLANLGDYNIGF----------GNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNI  680
            G AN+G +N+GF          GNLG DN+G A+ G +N+G AN G  N GFANTGD NI
Sbjct  708  GGANIGSFNVGFGSHGLDNFGSGNLGNDNVGPANVGDHNLGVANAGDGNAGFANTGDLNI  767

Query  681  GFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTG  740
            GFAN GSNNIGIGLTG+G++G G+LNSGS NIGLFNSG GN+GL NSG+GN GI N+GTG
Sbjct  768  GFANTGSNNIGIGLTGNGKVGIGALNSGSDNIGLFNSGTGNVGLLNSGNGNIGIANSGTG  827

Query  741  NWGIGNS--------------------GAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSY  780
            N GIGNS                    G GN GI NAG+ N+G +N+G  NTG  NPGSY
Sbjct  828  NIGIGNSGTANTGVANAGRHDTGLWNPGTGNTGIANAGADNSGAYNTGSTNTGIANPGSY  887

Query  781  NTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            NTGS NTGS NTG  N G+YNTG  NTGD
Sbjct  888  NTGSYNTGSTNTGLANTGDYNTGVANTGD  916


 Score =  396 bits (1017),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 275/550 (50%), Positives = 337/550 (62%), Gaps = 69/550 (12%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGF----------ANLGSDNLGLANLGG  247
              N+G  NVG  NVG+GNVG  NVG  N+GS+N+GF           NLG+DN+G AN+G 
Sbjct  685   LNVGSGNVGNLNVGSGNVGTHNVGGANIGSFNVGFGSHGLDNFGSGNLGNDNVGPANVGD  744

Query  248   HNI----------GFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNS  297
             HN+          GFANTG  N+GF NTGSNN+GIGLTGNG++G G+ NSGS NIGLFNS
Sbjct  745   HNLGVANAGDGNAGFANTGDLNIGFANTGSNNIGIGLTGNGKVGIGALNSGSDNIGLFNS  804

Query  298   GSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTG-----------W------------  334
             G+GNVGL NSG GN GI NSGTGN G+GN+G+ NTG           W            
Sbjct  805   GTGNVGLLNSGNGNIGIANSGTGNIGIGNSGTANTGVANAGRHDTGLWNPGTGNTGIANA  864

Query  335   -------FNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANT  387
                    +NTG  NTG  NPGSYNTG++NTG+ NTG  N G+YNTG  NTGDYNTG+ANT
Sbjct  865   GADNSGAYNTGSTNTGIANPGSYNTGSYNTGSTNTGLANTGDYNTGVANTGDYNTGLANT  924

Query  388   GNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPI-NAQLFSMPIHQVMVMPGSV  446
             GNV+TGAFIAGNYSNG  WRGDYQGL G    + IP  P+ N  +       + +   ++
Sbjct  925   GNVDTGAFIAGNYSNGFFWRGDYQGLYGFHAGIYIPEFPVLNMGIDIPINIPINLDAANI  984

Query  447   MTIPGMRLPFTSIVP----FVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGG  502
             +  P    P T  V       + +G + +P  +     V   +GGP T+I   +T  +G 
Sbjct  985   LVNPFAIQPITVSVLGSSYLSITFGTISIPALSGNGLAVDALIGGPDTSIPITITSALGP  1044

Query  503   VSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFG  562
             + I  I IPAAPGFGNST SPSSGFFN+G G+ASGFGN G   SG  NL  A  G+SG+ 
Sbjct  1045  IDITFIDIPAAPGFGNSTASPSSGFFNSGTGSASGFGNAGADTSGLRNLGGA--GVSGYR  1102

Query  563   NVGALGSGVANVGNTISGLYNTSTSNLATPAFNS----------GLLHHSV--GTMTLNF  610
             NVG+L SG+AN GNT+SG+YNTST  L  P   S          G+ H+S       LN 
Sbjct  1103  NVGSLESGLANWGNTVSGVYNTSTQGLTAPGNLSGYANTGTNLAGVFHNSTIPAGRVLNL  1162

Query  611   GLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNL  670
             G+AN G  N+G  N G  N+G  N+GD N+G GNLG  NLG  + G+ NIGFA+ G  NL
Sbjct  1163  GMANAGQLNMGFGNTGNINLGGGNVGDLNVGSGNLGSTNLGSGNIGNGNIGFAHNGDGNL  1222

Query  671   GFANTGDNNI  680
             G  NTG +NI
Sbjct  1223  GLGNTGSHNI  1232


 Score =  394 bits (1013),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 277/548 (51%), Positives = 340/548 (63%), Gaps = 55/548 (10%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIG------  251
              N+G  NVG +NVG  N+G FNVGFG+ G  N G  NLG+DN+G AN+G HN+G      
Sbjct  695   LNVGSGNVGTHNVGGANIGSFNVGFGSHGLDNFGSGNLGNDNVGPANVGDHNLGVANAGD  754

Query  252   ----FANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNS  307
                 FANTG  N+GF NTGSNN+GIGLTGNG++G G+ NSGS NIGLFNSG+GNVGL NS
Sbjct  755   GNAGFANTGDLNIGFANTGSNNIGIGLTGNGKVGIGALNSGSDNIGLFNSGTGNVGLLNS  814

Query  308   GTGNFGIGNSGTGNFGLGNTGSTNTG-----------W-------------------FNT  337
             G GN GI NSGTGN G+GN+G+ NTG           W                   +NT
Sbjct  815   GNGNIGIANSGTGNIGIGNSGTANTGVANAGRHDTGLWNPGTGNTGIANAGADNSGAYNT  874

Query  338   GDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIA  397
             G  NTG  NPGSYNTG++NTG+ NTG  N G+YNTG  NTGDYNTG+ANTGNV+TGAFIA
Sbjct  875   GSTNTGIANPGSYNTGSYNTGSTNTGLANTGDYNTGVANTGDYNTGLANTGNVDTGAFIA  934

Query  398   GNYSNGVLWRGDYQGLIGADIALEIPAIPI-NAQLFSMPIHQVMVMPGSVMTIPGMRLPF  456
             GNYSNG  WRGDYQGL G    + IP  P+ N  +       + +   +++  P    P 
Sbjct  935   GNYSNGFFWRGDYQGLYGFHAGIYIPEFPVLNMGIDIPINIPINLDAANILVNPFAIQPI  994

Query  457   TSIVP----FVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPA  512
             T  V       + +G + +P  +     V   +GGP T+I   +T  +G + I  I IPA
Sbjct  995   TVSVLGSSYLSITFGTISIPALSGNGLAVDALIGGPDTSIPITITSALGPIDITFIDIPA  1054

Query  513   APGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVA  572
             APGFGNST SPSSGFFN+G G+ASGFGN G   SG  NL  A  G+SG+ NVG+L SG+A
Sbjct  1055  APGFGNSTASPSSGFFNSGTGSASGFGNAGADTSGLRNLGGA--GVSGYRNVGSLESGLA  1112

Query  573   NVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGL  632
             N GNT+SG+YNTST  L  P   SG  + + GT      LA V  N+   A   + N+G+
Sbjct  1113  NWGNTVSGVYNTSTQGLTAPGNLSG--YANTGTN-----LAGVFHNSTIPAGR-VLNLGM  1164

Query  633   ANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGI  692
             AN G  N+GFGN G  NLG  + G  N+G  N GS NLG  N G+ NIGFA+ G  N+G+
Sbjct  1165  ANAGQLNMGFGNTGNINLGGGNVGDLNVGSGNLGSTNLGSGNIGNGNIGFAHNGDGNLGL  1224

Query  693   GLTGSGQI  700
             G TGS  I
Sbjct  1225  GNTGSHNI  1232


 Score =  287 bits (735),  Expect = 6e-75, Method: Compositional matrix adjust.
 Identities = 214/452 (48%), Positives = 260/452 (58%), Gaps = 83/452 (18%)

Query  417  DIALEIPA-IPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIV---PFVVYYGPVE--  470
            ++   IP  IPI A   +   H + +            +PF + V   P  V  G V   
Sbjct  2    NVVATIPIDIPIKASFTTTVYHGITID----------DIPFGTTVTLGPIPVLQGTVNSL  51

Query  471  -LPQSTLTLPTVTITVGGP--TTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGF  527
             +P  + T P   I +G P  +T I   ++  +G     +I I  APGFGNSTTSPSSGF
Sbjct  52   TIPPISATGPAPAIQIGSPDGSTAIVIPVSASLGPADWTIIDIGGAPGFGNSTTSPSSGF  111

Query  528  FNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTS  587
            FNAG GTASGF NFG   SG  N   A+SG SG+ NVG L SG+AN+GNT+SGL NTST 
Sbjct  112  FNAGTGTASGFANFGADNSGLLN---ASSGSSGYKNVGDLVSGMANLGNTVSGLLNTSTL  168

Query  588  NLATPAFNSG----------LLHHSVGTM-TLNFGLANVGGNNVGGANAGIFNVGLANLG  636
            +LATPA  SG          L   S   M T N G  NVG            NVG  N+G
Sbjct  169  DLATPANVSGVANIGANLSGLYRDSAAAMSTFNVGFGNVG----------TLNVGFGNIG  218

Query  637  DYNIGFGNLGGDNLGFAHAGSYNI------------------------------------  660
            DYN+G GN+G  N+G A+ G++N+                                    
Sbjct  219  DYNLGSGNVGDLNVGSANVGNHNVGGANIGNVNVGFGSHGLHNIGSANLGNDNFGPANFG  278

Query  661  ----GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFN  716
                GFAN G+ N+G ANTGD NIG AN GSNNIGIGLTG+G++G G+LNSGS N GLFN
Sbjct  279  DDNRGFANAGNANIGLANTGDGNIGLANTGSNNIGIGLTGNGKVGIGALNSGSGNTGLFN  338

Query  717  SGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776
            SG  N GLFNSG+GN GI N+GTGNWGIGNSG+ N G GN+G  NTGL+N+G++N+G  N
Sbjct  339  SGTDNAGLFNSGTGNVGIANSGTGNWGIGNSGSTNTGFGNSGMVNTGLWNAGNVNSGIGN  398

Query  777  PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
             G YN+GS N GS NT GFN G+YNTGY NTG
Sbjct  399  TGDYNSGSFNAGSFNTAGFNPGSYNTGYSNTG  430


 Score = 70.1 bits (170),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 85/210 (41%), Positives = 103/210 (50%), Gaps = 27/210 (12%)

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            G  NAG G A GF N G    GF N  S   G+   GN G +G G  N G+   GL+N+ 
Sbjct  748  GVANAGDGNA-GFANTGDLNIGFANTGSNNIGIGLTGN-GKVGIGALNSGSDNIGLFNSG  805

Query  586  TSNLATPAFNSGLLHHSVGTM------TLNFGLANVGGNNVGGANAGIFNVGLANLGDYN  639
            T N+       GLL+   G +      T N G+ N G  N G ANAG  + GL N G  N
Sbjct  806  TGNV-------GLLNSGNGNIGIANSGTGNIGIGNSGTANTGVANAGRHDTGLWNPGTGN  858

Query  640  IGFGNLGGDN----------LGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNN  689
             G  N G DN           G A+ GSYN G  NTGS N G ANTGD N G AN G  N
Sbjct  859  TGIANAGADNSGAYNTGSTNTGIANPGSYNTGSYNTGSTNTGLANTGDYNTGVANTGDYN  918

Query  690  IGIGLTGSGQIGFGSLNSGSHNIGLFNSGD  719
               GL  +G +  G+  +G+++ G F  GD
Sbjct  919  --TGLANTGNVDTGAFIAGNYSNGFFWRGD  946


 Score = 62.8 bits (151),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 100/295 (34%), Positives = 141/295 (48%), Gaps = 31/295 (10%)

Query  131  PAIAATEAAYERMWAQDVAAMVGYHAGASAAV----SALMPFTQQLKKLAGL-----SER  181
            P I+AT  A         A  +G   G++A V    ++L P    +  + G      S  
Sbjct  54   PPISATGPA--------PAIQIGSPDGSTAIVIPVSASLGPADWTIIDIGGAPGFGNSTT  105

Query  182  LTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLG  241
              S+    AG  +A+GF    AN GA+N G  N    + G+ N+G    G ANLG+   G
Sbjct  106  SPSSGFFNAGTGTASGF----ANFGADNSGLLNASSGSSGYKNVGDLVSGMANLGNTVSG  161

Query  242  LANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGN  301
            L N    ++    T +N  G  N G+N  G  L  +      +FN G  N+G  N G GN
Sbjct  162  LLNTSTLDLA---TPANVSGVANIGANLSG--LYRDSAAAMSTFNVGFGNVGTLNVGFGN  216

Query  302  VGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYN  361
            +G +N G+GN G       N G  N G+ N G  N G+VN G  + G +N G+ N GN N
Sbjct  217  IGDYNLGSGNVG-----DLNVGSANVGNHNVGGANIGNVNVGFGSHGLHNIGSANLGNDN  271

Query  362  TGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGA  416
             G  N G+ N G+ N G+ N G+ANTG+ N G    G+ + G+   G+ +  IGA
Sbjct  272  FGPANFGDDNRGFANAGNANIGLANTGDGNIGLANTGSNNIGIGLTGNGKVGIGA  326


 Score = 43.9 bits (102),  Expect = 0.15, Method: Compositional matrix adjust.
 Identities = 42/124 (34%), Positives = 59/124 (48%), Gaps = 12/124 (9%)

Query  144   WAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGL-------SERLTSAAAAAAGPPSAA  196
             W   V+ +         A   L  +      LAG+       + R+ +   A AG  +  
Sbjct  1114  WGNTVSGVYNTSTQGLTAPGNLSGYANTGTNLAGVFHNSTIPAGRVLNLGMANAGQLNMG  1173

Query  197   GFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTG  256
               N G  N+G  NVG+      NVG GNLGS NLG  N+G+ N+G A+ G  N+G  NTG
Sbjct  1174  FGNTGNINLGGGNVGD-----LNVGSGNLGSTNLGSGNIGNGNIGFAHNGDGNLGLGNTG  1228

Query  257   SNNV  260
             S+N+
Sbjct  1229  SHNI  1232


 Score = 42.7 bits (99),  Expect = 0.29, Method: Compositional matrix adjust.
 Identities = 62/158 (40%), Positives = 79/158 (50%), Gaps = 12/158 (7%)

Query  641   GFGNLGGDNLGFAHAGSYNI-GFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQ  699
             GFGN G D  G  + G   + G+ N GS   G AN G+   G  N  +     GLT  G 
Sbjct  1079  GFGNAGADTSGLRNLGGAGVSGYRNVGSLESGLANWGNTVSGVYNTSTQ----GLTAPGN  1134

Query  700   IGFGSLNSGSHNIGLFNSGDG------NIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFG  753
             +  G  N+G++  G+F++         N+G+ N+G  N G GN G  N G GN G  N G
Sbjct  1135  LS-GYANTGTNLAGVFHNSTIPAGRVLNLGMANAGQLNMGFGNTGNINLGGGNVGDLNVG  1193

Query  754   IGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GN GSTN G  N G+ N G  + G  N G  NTGS N
Sbjct  1194  SGNLGSTNLGSGNIGNGNIGFAHNGDGNLGLGNTGSHN  1231


 Score = 40.0 bits (92),  Expect = 2.1, Method: Compositional matrix adjust.
 Identities = 28/75 (38%), Positives = 35/75 (47%), Gaps = 0/75 (0%)

Query  761  NTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQY  820
            N G  N G LN G  N G YN GS N G +N G  N GN+N G  N G++    G H  +
Sbjct  201  NVGFGNVGTLNVGFGNIGDYNLGSGNVGDLNVGSANVGNHNVGGANIGNVNVGFGSHGLH  260

Query  821  QHRRFHLRQPQQRPS  835
                 +L      P+
Sbjct  261  NIGSANLGNDNFGPA  275


 Score = 40.0 bits (92),  Expect = 2.4, Method: Compositional matrix adjust.
 Identities = 28/59 (48%), Positives = 34/59 (58%), Gaps = 0/59 (0%)

Query  751   NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
             N G+ NAG  N G  N+G++N G  N G  N GS N GS N G  N GN N G+ + GD
Sbjct  1161  NLGMANAGQLNMGFGNTGNINLGGGNVGDLNVGSGNLGSTNLGSGNIGNGNIGFAHNGD  1219


 Score = 38.5 bits (88),  Expect = 5.5, Method: Compositional matrix adjust.
 Identities = 61/153 (40%), Positives = 75/153 (50%), Gaps = 18/153 (11%)

Query  661  GFANTGS-NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGD  719
            GF N+G+ ++ G AN G NN GF N  S N GI    SG    G L SG  N G   SG 
Sbjct  587  GFFNSGAGSSSGLANVGPNNSGFFN-ASGNSGI----SGYKNVGDLVSGMANFGNTVSG-  640

Query  720  GNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGS  779
                L N+ + + G     +G   +G+  AG FG       N+ + N G  N GSLN GS
Sbjct  641  ----LLNTSTLDLGTPANVSGVANVGSDVAGFFG-------NSAVSNLGFANDGSLNVGS  689

Query  780  YNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQH  812
             N G++N GS N G  N G  N G FN G   H
Sbjct  690  GNVGNLNVGSGNVGTHNVGGANIGSFNVGFGSH  722


>gi|308376082|ref|ZP_07446012.2| putative PPE family protein [Mycobacterium tuberculosis SUMu007]
 gi|308344372|gb|EFP33223.1| putative PPE family protein [Mycobacterium tuberculosis SUMu007]
Length=1338

 Score =  562 bits (1448),  Expect = 1e-157, Method: Compositional matrix adjust.
 Identities = 469/1008 (47%), Positives = 550/1008 (55%), Gaps = 236/1008 (23%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M FVV  PE+NSL +Y GAG GP+LAAAAAWD LA EL  AA+ FGSVTSGL    W+GP
Sbjct  1    MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            ++VAMA A APY GWL +A A AE AA QAR  V  FEAA AATV P ++AANR+ LVSL
Sbjct  61   SSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
              SNL G N PAIAA E  YE MWAQDVAAM+GYH GASAA  AL PF   L  LA  +E
Sbjct  121  ALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAE  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSY------------  228
               S A            NLGLANVG  N G+GNVG +NVG GN+GSY            
Sbjct  181  PAKSLAV-----------NLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNV  229

Query  229  --------NLGFAN-------LGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIG  273
                    N G  N       +G  N+G  N G +N G AN G  N+GF NTGS N GIG
Sbjct  230  GLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIG  289

Query  274  LTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTG  333
            LTG+   GFG FN+GS N+GLFNSG+GNVG FNSGTGN+G+ NSG+ N G+GN+G  +TG
Sbjct  290  LTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTG  349

Query  334  WFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTG  393
             FN G  NTG  N GSYNTG+FN G  NTG FN G+ NTG+ NTGD NTGVAN+G+VNTG
Sbjct  350  LFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTG  409

Query  394  AFIAGNYSNGVLWRGDYQGLIG-------------ADIALE-------IPAIPINA----  429
            AFI+GNYSNG  WRGDYQGL+G              D+ L        IPAI I A    
Sbjct  410  AFISGNYSNGAFWRGDYQGLLGFSYRPAVLPQTPFLDLTLTGGLGSVVIPAIDIPAIRPE  469

Query  430  ----------QLFSMPIHQVMVMPGSV------MTIPGMRLPFTSIVPFVVYY-------  466
                       + S+PI Q+ +   +V      +T+P + +P    VP  + Y       
Sbjct  470  FSANVAIDSFTVPSIPIPQIDLAATTVSVGLGPITVPHLDIPR---VPVTLNYLFGSQPG  526

Query  467  GPVEL---------------------------PQSTLTLPTVTITVGGPTTTIDG-----  494
            GP+++                            Q T+T     +    P  TID      
Sbjct  527  GPLKIGPITGLFNTPIGLTPLALSQIVIGASSSQGTITAFLANLPFSTPVVTIDEIPLLA  586

Query  495  --------------------------NLTGMVGGVSIP----------------------  506
                                      NL+G  G V+IP                      
Sbjct  587  SITGHSEPVDIFPGGLTIPAMNPLSINLSGGTGAVTIPAITIGEIPFDLVAHSTLGPVHI  646

Query  507  LIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASAT--SGLSGFGNV  564
            LI +PA PGFGN+T +PSSGFFN+GAG  SGFGN G   SG WN A +    G SG  N 
Sbjct  647  LIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNA  706

Query  565  GALGSGVANVGNTISGLYNTSTSNLATPAFNSGL----------------LHHSVGTMTL  608
            G L SGV N G+ +SGL+NTS   L  PA  SGL                LH     + L
Sbjct  707  GTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQG---LVL  763

Query  609  NFGLANVGGNNVGGANAGIFNVGLANLGDYNIG-------------------------FG  643
            NFGLA+VG          + NVGL N+GD+N+G                         +G
Sbjct  764  NFGLADVG----------LGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWG  813

Query  644  NLGGDNLGFAH--AGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIG  701
            N G  N G      G  NIGF N GS N G AN G  NIGFAN GS N GIGLTG    G
Sbjct  814  NFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTG  873

Query  702  FGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTN  761
            FG  N+GS N+GLFNSG GN+G FNS          GTGNWG+ NSG+ N GIGN+G  +
Sbjct  874  FGGFNTGSGNVGLFNSGTGNVGFFNS----------GTGNWGVFNSGSYNTGIGNSGIAS  923

Query  762  TGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
            TGLFN+G  NTG +N GSYNTGS N G  NTGGFN G+ NTG+ NTGD
Sbjct  924  TGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGD  971


 Score =  229 bits (585),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 171/367 (47%), Positives = 205/367 (56%), Gaps = 52/367 (14%)

Query  157   GASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVG  216
             GA A VS L    QQL  L      L S  A   G       N GLA+VG  NVG GNVG
Sbjct  732   GAPALVSGLGSVGQQLSGL------LASGTALHQG----LVLNFGLADVGLGNVGLGNVG  781

Query  217   VFNVG-------------------------FGNLGSYNLGFAN--LGSDNLGLANLGGHN  249
              FN+G                         +GN G  N G     +G  N+G  N G +N
Sbjct  782   DFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYN  841

Query  250   IGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGT  309
              G AN G  N+GF NTGS N GIGLTG+   GFG FN+GS N+GLFNSG+GNVG FNSGT
Sbjct  842   FGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGT  901

Query  310   GNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGN  369
             GN+G+ NSG+ N G+GN+G  +TG FN G  NTG  N GSYNTG+FN G  NTG FN G+
Sbjct  902   GNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGS  961

Query  370   YNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIG----ADIALEIPAI  425
              NTG+ NTGD NTGVAN+G+VNTGAFI+GNYSNG  WRGDYQGL+G    + I  E    
Sbjct  962   VNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVA  1021

Query  426   PINAQ----LFSMPIHQVMVMPGSVMT---IPGMRLPFTSIVPFVVYYGPV----ELPQS  474
              I+A        +P  Q   +P  +     I G  +P  SI P  V   PV     +   
Sbjct  1022  NIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQ  1081

Query  475   TLTLPTV  481
              +T+P +
Sbjct  1082  DITIPAL  1088


 Score =  171 bits (434),  Expect = 5e-40, Method: Compositional matrix adjust.
 Identities = 119/223 (54%), Positives = 138/223 (62%), Gaps = 27/223 (12%)

Query  605  TMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIG---------------FGNLGGDN  649
            ++ +N GLANVG  N G  N G +NVG  N+G YN+G               +GN G  N
Sbjct  184  SLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGN  243

Query  650  LGFAH--AGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNS  707
             G      G  NIGF N GS N G AN G  NIGFAN GS N GIGLTG    GFG  N+
Sbjct  244  SGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNT  303

Query  708  GSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNS  767
            GS N+GLFNSG GN+G FNS          GTGNWG+ NSG+ N GIGN+G  +TGLFN+
Sbjct  304  GSGNVGLFNSGTGNVGFFNS----------GTGNWGVFNSGSYNTGIGNSGIASTGLFNA  353

Query  768  GDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDL  810
            G  NTG +N GSYNTGS N G  NTGGFN G+ NTG+ NTGD+
Sbjct  354  GGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDI  396


 Score = 70.1 bits (170),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 66/171 (39%), Positives = 84/171 (50%), Gaps = 20/171 (11%)

Query  447   MTIPGMRLPFTSI---VPFVVYYGPVELPQSTLTLPTVTITVGGPT--------TTIDG-  494
             +TIPG  +P   I   +P  V  GP   P+ T+    + + + G T         TID  
Sbjct  1152  ITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRI  1211

Query  495   ----NLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTA-SGFGNFGGGASGFW  549
                 ++  ++G ++  L+ IP  PGFGN+T  PSSGFFN G G   SGF N G G SG  
Sbjct  1212  PVVLDVNALLGPINAGLV-IPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVL  1270

Query  550   NLAS--ATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
             N  S       SGF N G   SG+ N G  ISG+YNT    L T A  SG 
Sbjct  1271  NAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGF  1321


 Score = 55.1 bits (131),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 69/171 (41%), Positives = 81/171 (48%), Gaps = 22/171 (12%)

Query  515  GFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGF----GNVGALGSG  570
            GFGN+  S + G  N G G   GF N G G  G        +G  GF    GNVG   SG
Sbjct  833  GFGNAG-SYNFGLANMGVGNI-GFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSG  890

Query  571  VANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNV  630
              NVG      +N+ T N     FNSG         + N G+ N G  + G  NAG FN 
Sbjct  891  TGNVG-----FFNSGTGNWG--VFNSG---------SYNTGIGNSGIASTGLFNAGGFNT  934

Query  631  GLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIG  681
            G+ N G YN G  N G  N G  + GS N G+ NTG  N G AN+GD N G
Sbjct  935  GVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTG  985


>gi|306801949|ref|ZP_07438617.1| PPE family protein [Mycobacterium tuberculosis SUMu008]
 gi|308351300|gb|EFP40151.1| PPE family protein [Mycobacterium tuberculosis SUMu008]
Length=3253

 Score =  561 bits (1446),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 405/872 (47%), Positives = 492/872 (57%), Gaps = 107/872 (12%)

Query  163   SALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGF  222
             + +  F   L  +   +   ++   + AG  +   FNLG  N+G+ NV  GN G +N+G 
Sbjct  1465  TGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLGSGNLGSFNVFGGNQGSYNIGP  1524

Query  223   GNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGF  282
              NLG+YN+G  NLGS N G  N G  N+GFANTG+NN+GF NTG+NN+GIGL+G+ Q GF
Sbjct  1525  ANLGNYNIGLGNLGSYNFGFGNAGDFNLGFANTGNNNIGFANTGNNNIGIGLSGDNQQGF  1584

Query  283   ---GSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGD  339
                G +NSGS N GLFNSG+ N+GLFNSGTGN GIGNSGTGN+G+ NTG TNTG FNTGD
Sbjct  1585  NFAGGWNSGSGNSGLFNSGTNNIGLFNSGTGNIGIGNSGTGNWGIANTGDTNTGIFNTGD  1644

Query  340   VNTGGFNPGSYNTGNFNTGNYNTGSFNAGN----------YNTGYFNTGDYNTGVANTGN  389
             VNTG  N G+ NTG FNTG+YNTGSFNAG+          YNTGY NTG YNTG+AN+G+
Sbjct  1645  VNTGLLNAGNVNTGIFNTGHYNTGSFNAGSFNTAGFNPGSYNTGYLNTGSYNTGLANSGD  1704

Query  390   VNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSV--M  447
             VNTG FI GNYSNG  WRGDYQGL G    + +P   +  +L  +PI   + + G++   
Sbjct  1705  VNTGGFITGNYSNGFWWRGDYQGLAGISQTITVPDTAVPVKL-HVPIFLDIPVTGTLGTF  1763

Query  448   TIPGMRLP------FTSIVPF-VVYYGPVELPQSTLTLPTVTITVG-GPTTTIDGNLTGM  499
             T+ G R P      F   +PF          P  ++ LP + I +G GP   ID   TG 
Sbjct  1764  TVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNISIVLPNIGINLGSGPDPLIDIAGTGG  1823

Query  500   VGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLS  559
             +  + IPLI IPAAPGFGNSTT+PSSGFFNAG GT SG GN G  +SGF+NL S +SG+S
Sbjct  1824  LLPIKIPLIDIPAAPGFGNSTTTPSSGFFNAGTGTVSGVGNVGSNSSGFFNLTSGSSGIS  1883

Query  560   GFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSG-------LLHHSVGTMTLNFGL  612
             G  N G L SG  N GNT+SGL N ST  L+ PA  SG       +      T  LN G 
Sbjct  1884  GVQNFGELISGGFNFGNTVSGLVNASTLGLSMPANLSGGGNVGATVAGFVNNTQILNLGF  1943

Query  613   ANVGGNNVGGANAGIFNVGLANLGD--------------------YNIGFGNLGGDNLGF  652
              NVG  NVG  N G  NVGL NLG+                    YNIG  NLG  N+G 
Sbjct  1944  GNVGSGNVGHGNIGDSNVGLGNLGNANVGHGNIGSFNVFSGNRGSYNIGPANLGNYNIGL  2003

Query  653   AHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNI  712
              + GSYN GF N G  NLGFAN+G NNIGFAN G+NNIGIGL+G  Q GFGS NSG+ N 
Sbjct  2004  GNLGSYNFGFGNAGDFNLGFANSGSNNIGFANTGNNNIGIGLSGHNQQGFGSWNSGTANT  2063

Query  713   GLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNA---------------  757
             GLFNSG  NIGLFNSG+GN GIGN+G GN GIGN G GN G+GN+               
Sbjct  2064  GLFNSGTNNIGLFNSGTGNIGIGNSGIGNTGIGNPGVGNTGLGNSGTGNWGLWNPGTGNM  2123

Query  758   ---------------GSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNT  802
                            GSTNTG+ N G  NTGS N GS NTGS N G  NTG +N G+YNT
Sbjct  2124  GVANVGTYNTGGYNVGSTNTGIANVGIANTGSYNTGSTNTGSFNDGDFNTGFYNTGDYNT  2183

Query  803   GYFNTGDL--------QHRHGEHRQYQHR-RFHLRQPQQRPSVAGRQPGSDRPRHRRRHS  853
             G++NTGD+           +G   Q  H+ ++        P +       + P +   H 
Sbjct  2184  GFYNTGDVNTGAFIGGNFSNGAFWQSDHQGQWGAHYAITVPQIPLLNFSLNIPVNIPIH-  2242

Query  854   RNPDCERRREYPDSHTDHRQLHGHRIQ-RARSSTEHSRHCYFFRTRRYRPLHRPSDTDNR  912
              +        +       R L GH +Q R    +E  RH    R +  RP     DT   
Sbjct  2243  LDFGTLAVNGFQIPAITLRALGGHPLQRRTHHRSEDRRHLTGDRYQHRRPRRFILDT---  2299

Query  913   SHTCGHGGWTHYRDQYRRHCGRRRHQ-HPDYP  943
                        + D  RR  GR     HP  P
Sbjct  2300  -----------HHDHQRRRPGRHPATGHPAGP  2320


 Score =  546 bits (1407),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 365/706 (52%), Positives = 458/706 (65%), Gaps = 50/706 (7%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             FN+G  N+G  NVG+G++G +N+G GNLG YN+GF N+G  N+G  N G  N GFANTG+
Sbjct  587   FNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNVGDYNVGFGNAGDFNQGFANTGN  646

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGF-------------GSFNSGSHNIGLFNSGSGNVGL  304
             NN+GF NTG+NN+GIGL+G+ Q GF             G FNSG++N+G+FN+G+GNVG+
Sbjct  647   NNIGFANTGNNNIGIGLSGDNQQGFNIASGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGI  706

Query  305   FNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGS  364
              NSGTGN+GIGN GT N G+ N GS NTG  N GD NTG +N GSYNTG FN GN NTG+
Sbjct  707   ANSGTGNWGIGNPGTDNTGILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGN  766

Query  365   FNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPA  424
             FN G+ NTG +N GD NTG  N GNVNTGAF  G+++NG L  GD QG I  D+++  P 
Sbjct  767   FNVGDTNTGSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAIDLSVTTPF  826

Query  425   IPINAQLFSMPIHQVMVMPGSVMTI--PGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVT  482
             IPIN Q+  + +H VM   G+++T+       P T  +  + ++GPV L  STLT+PT+T
Sbjct  827   IPINEQMV-IDVHNVMTFGGNMITVTEASTVFPQTFYLSGLFFFGPVNLSASTLTVPTIT  885

Query  483   ITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFG  542
             +T+GGPT T+  ++ G +   +I  +KI  APG GNSTT+PSSGFFN+G G  SGF N G
Sbjct  886   LTIGGPTVTVPISIVGALESRTITFLKIDPAPGIGNSTTNPSSGFFNSGTGGTSGFQNVG  945

Query  543   GGASGFWN--LASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
             GG+SG WN  L+SA  G SGF N+G+L SG AN+GN++SG +NTST NL+TPA  SGL  
Sbjct  946   GGSSGVWNSGLSSAI-GNSGFQNLGSLQSGWANLGNSVSGFFNTSTVNLSTPANVSGL--  1002

Query  601   HSVGT-----------MTLNFGLANVGGNNVGGANAGIFNVGLANL----------GDYN  639
             +++GT              N GLAN+G  N+G AN G FN+G  N+          G YN
Sbjct  1003  NNIGTNLSGVFRGPTGTIFNAGLANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYN  1062

Query  640   IGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQ  699
             IG  NLG  N+GFA+ G+YNIGF N G  N GFANTG+NNIGFAN G+NNIGIGL+G  Q
Sbjct  1063  IGPANLGNYNIGFANLGNYNIGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQ  1122

Query  700   IGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGS  759
              GF       +  G +NSG  NIGLFNSG+ N GIGN+GTGNWGIGNSG+GN GIGN GS
Sbjct  1123  QGF-------NFAGGWNSGTANIGLFNSGTNNVGIGNSGTGNWGIGNSGSGNTGIGNTGS  1175

Query  760   TNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQ  819
             TNTG FN+G +NTG  N GSYNTG  NTG  NTG  N G++NTG++NTG+          
Sbjct  1176  TNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNTGIANLGDFNTGFYNTGNFSTGFANQGD  1235

Query  820   YQHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYP  865
                  F            G Q G     +R      P      E P
Sbjct  1236  IATGAFITGDMGNGAFWRGDQQGLFSAGYRVHVPEIP-AHVTVEVP  1280


 Score =  498 bits (1283),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 345/658 (53%), Positives = 429/658 (66%), Gaps = 52/658 (7%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             FNLG  NVG+ NV +GN G +N+G  NLG+YN+GFANLG+ N+G  N G  N GFANTG+
Sbjct  1041  FNLGSGNVGSFNVFSGNQGSYNIGPANLGNYNIGFANLGNYNIGFGNAGDFNQGFANTGN  1100

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGF---GSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGI  314
             NN+GF NTG+NN+GIGL+G+ Q GF   G +NSG+ NIGLFNSG+ NVG+ NSGTGN+GI
Sbjct  1101  NNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGTANIGLFNSGTNNVGIGNSGTGNWGI  1160

Query  315   GNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGY  374
             GNSG+GN G+GNTGSTNTG+FNTG VNTG  N GSYNTG +NTG+ NTG  N G++NTG+
Sbjct  1161  GNSGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNTGIANLGDFNTGF  1220

Query  375   FNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQL---  431
             +NTG+++TG AN G++ TGAFI G+  NG  WRGD QGL  A   + +P IP +  +   
Sbjct  1221  YNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQGLFSAGYRVHVPEIPAHVTVEVP  1280

Query  432   FSMPIHQVMV-MPGSVMTIPGMRLPFT-SIVPFVVYYGPVE---LPQSTLTLPTVTITVG  486
              ++PI         S +T+  +   FT  I    +  G +    LP  T T P +T+ +G
Sbjct  1281  VNIPITASFTNTVYSGITLEQINFGFTIDIAGIPLLAGAISKAVLPPITGTGPAITVNIG  1340

Query  487   GP--TTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGG  544
              P  +T I    T  VG   +  + I A  GF N+TT PSSGFFN G GT SG  N G  
Sbjct  1341  DPGGSTAIRIPATASVGPFDVTFVNIAATTGFFNATTDPSSGFFNGGPGTVSGIANIGAN  1400

Query  545   ASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH----  600
              SGF N+A++ +  SGF N G+L SG+AN+G+T+SG++NT    +  PA  SG+ +    
Sbjct  1401  ISGFQNVANSAT--SGFNNYGSLQSGLANLGDTVSGVFNTG---IGAPANVSGMFNIGSN  1455

Query  601   -------HSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGG------  647
                     + G    N GL N+G  NVG +N G  N GLAN+G +N+G GNLG       
Sbjct  1456  LAGFFHDQATGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLGSGNLGSFNVFGG  1515

Query  648   --------------DNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIG  693
                            N+G  + GSYN GF N G  NLGFANTG+NNIGFAN G+NNIGIG
Sbjct  1516  NQGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDFNLGFANTGNNNIGFANTGNNNIGIG  1575

Query  694   LTGSGQIGF---GSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG  750
             L+G  Q GF   G  NSGS N GLFNSG  NIGLFNSG+GN GIGN+GTGNWGI N+G  
Sbjct  1576  LSGDNQQGFNFAGGWNSGSGNSGLFNSGTNNIGLFNSGTGNIGIGNSGTGNWGIANTGDT  1635

Query  751   NFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
             N GI N G  NTGL N+G++NTG  N G YNTGS N GS NT GFN G+YNTGY NTG
Sbjct  1636  NTGIFNTGDVNTGLLNAGNVNTGIFNTGHYNTGSFNAGSFNTAGFNPGSYNTGYLNTG  1693


 Score =  427 bits (1097),  Expect = 6e-117, Method: Compositional matrix adjust.
 Identities = 334/710 (48%), Positives = 425/710 (60%), Gaps = 85/710 (11%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFG------------NLGSYNLGFANLGSD  238
             G  +A  FN G+AN G NN+G  N G  NVG G            N G+ N GF N G+ 
Sbjct  2554  GMANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGFFNSGTA  2613

Query  239   NLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSG  298
             N GL N G  N G  N+G+ NVG GN G+   G+GL+G+ Q+G G  NSGS NIGLFNSG
Sbjct  2614  NTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDSQVGIGGTNSGSFNIGLFNSG  2673

Query  299   SGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTG  358
             +GNVG+ NSGTGN GIGN+GTGN G+GN+G+ NTG  N G VNTG  NPG++NTG FN G
Sbjct  2674  TGNVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNAGLVNTGIANPGNHNTGLFNIG  2733

Query  359   NYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD-  417
              +NTG  N G+YNTG +NTG YNTG+AN G+  TGAFI G+ +NG+LWR D QGL+ A+ 
Sbjct  2734  TFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAFITGSMNNGLLWRADRQGLLAANY  2793

Query  418   -IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSI---VPFVVYYGPVELPQ  473
              I +E PA  +N  +   P++  +    + ++IP +  P       V   +  G V  P 
Sbjct  2794  TITIERPAAFLNVDI---PVNIPITGDITNVSIPAITFPRIDASGSVDIGILSGTVLAPV  2850

Query  474   STLTL--------------------PTVTITVGGPTTTIDGNLTGMVGG--VSIPLIKIP  511
               +TL                    P + + +G P  +   N+ G  G   +SIP+I + 
Sbjct  2851  GPITLHGGDASAPLDTPIEIDFGPSPAINLNIGKPDGSTVINIVGGAGAGPISIPIIDLR  2910

Query  512   AAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGV  571
              APGF N+TT PSSGF N GAG+ASG  NFG   SG +N A+++ G SGF N G+L SG 
Sbjct  2911  PAPGFFNATTGPSSGFLNWGAGSASGLLNFGN-NSGLYNFATSSMGNSGFQNYGSLQSGW  2969

Query  572   ANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGT------------MTLNFGLANVGGNN  619
             AN+GN+ISG+YNT    L  PA  SGLL+  +GT             T + GLAN+G  N
Sbjct  2970  ANLGNSISGIYNTG---LGAPANVSGLLN--IGTNLAGWLQNGPTETTFSVGLANLGFWN  3024

Query  620   VGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDN-  678
             +G AN G +N+G AN+G YN+G  N+G  NLG A+ G +N+G AN GS+N+GF N G   
Sbjct  3025  LGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGSANIGSSNIGFGNVGPGL  3084

Query  679   -----NIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFG  733
                  NIGF N G+ NIGIG TG+G IGFG  N+G+ N G+ NSGD N G+ N+GS N G
Sbjct  3085  TAAIGNIGFGNTGNGNIGIGNTGTGNIGFG--NTGTGNWGIGNSGDYNTGIGNTGSTNSG  3142

Query  734   IGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGS---------  784
               N G  N GIGNSG  N G+ NAG+TNTG FN GD NTG  NPG+YNTG          
Sbjct  3143  FFNTGLVNTGIGNSGDYNTGLFNAGNTNTGSFNPGDYNTGGFNPGNYNTGYFNPGNSNTG  3202

Query  785   -VNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQ-------YQHRRFH  826
               N+G VNTG FN+GNY+ G+F  GD Q   G   Q       + + RF 
Sbjct  3203  IANSGDVNTGAFNSGNYSNGFFWRGDYQGLGGFAYQSAVSEIPWSYDRFQ  3252


 Score =  377 bits (969),  Expect = 5e-102, Method: Compositional matrix adjust.
 Identities = 270/440 (62%), Positives = 317/440 (73%), Gaps = 38/440 (8%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M F V  PE+NS R+Y+GAG  PML AAAAWDGLADEL  AA+ F +VT+GLA ++W G 
Sbjct  1    MSFAVLPPEINSARLYVGAGLAPMLDAAAAWDGLADELGSAAASFSAVTAGLAGSSWLGA  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            A+ AM  A APYLGWL +A AQA+QAA Q R+A A FEAA AATVHPAI++ANRA+ VSL
Sbjct  61   ASTAMTGAAAPYLGWLSAAAAQAQQAATQTRLAAAAFEAALAATVHPAIISANRALFVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            V SNLLG NAPAIAATEAAYE+MWAQDVAAM GYHAGASAAVSAL PF Q L  +AG   
Sbjct  121  VVSNLLGQNAPAIAATEAAYEQMWAQDVAAMFGYHAGASAAVSALTPFGQALPTVAGGGA  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGAN---------------NVGNGNVGVFNVGFGNL  225
             +++AAA      +    NLGLANVG                 N+GNGN+G      GN+
Sbjct  181  LVSAAAAQVT---TRVFRNLGLANVGEGNVGNGNVGNFNLGSANIGNGNIGS-----GNI  232

Query  226  GSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQ------  279
            GS N+GF N+G       N    NIGF NTGSNN+GFGNTGSNN+G G TG+G       
Sbjct  233  GSSNIGFGNVGPGLTAALN----NIGFGNTGSNNIGFGNTGSNNIGFGNTGDGNRGIGLT  288

Query  280  ----IGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTG-NFGLGNTGSTNTGW  334
                +GFG  NSG+ NIGLFNSG+GNVG+ NSGTGN+GIGNSG   N G GN+G  NTG+
Sbjct  289  GSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGNSYNTGFGNSGDANTGF  348

Query  335  FNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGA  394
            FN+G  NTG  N G+YNTG++N GN NTG FN G YNTGY N+G+YNTG+AN+GNVNTGA
Sbjct  349  FNSGIANTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGA  408

Query  395  FIAGNYSNGVLWRGDYQGLI  414
            FI GN++NG LWRGD+QGLI
Sbjct  409  FITGNFNNGFLWRGDHQGLI  428


 Score =  375 bits (962),  Expect = 3e-101, Method: Compositional matrix adjust.
 Identities = 327/783 (42%), Positives = 408/783 (53%), Gaps = 164/783 (20%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFG--NLGSYNLGFANLGSDNLGLANLGGHNIGFANT  255
             +N+G  N G NN+G G  G   +GFG  N G  N+G  NLG +N G+AN G  N G ANT
Sbjct  2509  YNIGFGNTGNNNIGIGLSGDNQIGFGPLNAGIANMGLFNLGDNNFGMANAGNFNQGIANT  2568

Query  256   GSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIG  315
             G+NN+G  NTG+NNVGIGLTG+G  GF S NSG+ N G FNSG+ N GLFNSGTGN    
Sbjct  2569  GNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGFFNSGTANTGLFNSGTGN----  2624

Query  316   NSGTGNFGLGNTGSTNTGWFNT--GDVNTGGF---------------NPGSYNTGNF---  355
                        TG  N+G  N   G++ TGGF               N GS+N G F   
Sbjct  2625  -----------TGLFNSGTGNVGIGNMGTGGFGVGLSGDSQVGIGGTNSGSFNIGLFNSG  2673

Query  356   ---------------------------NTGNYNTGSFNA---------------------  367
                                        N+GNYNTG  NA                     
Sbjct  2674  TGNVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNAGLVNTGIANPGNHNTGLFNIG  2733

Query  368   ---------GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD-  417
                      G+YNTG +NTG YNTG+AN G+  TGAFI G+ +NG+LWR D QGL+ A+ 
Sbjct  2734  TFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAFITGSMNNGLLWRADRQGLLAANY  2793

Query  418   -IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSI---VPFVVYYGPVELPQ  473
              I +E PA  +N  +   P++  +    + ++IP +  P       V   +  G V  P 
Sbjct  2794  TITIERPAAFLNVDI---PVNIPITGDITNVSIPAITFPRIDASGSVDIGILSGTVLAPV  2850

Query  474   STLTL--------------------PTVTITVGGPTTTIDGNLTGMVGG--VSIPLIKIP  511
               +TL                    P + + +G P  +   N+ G  G   +SIP+I + 
Sbjct  2851  GPITLHGGDASAPLDTPIEIDFGPSPAINLNIGKPDGSTVINIVGGAGAGPISIPIIDLR  2910

Query  512   AAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGV  571
              APGF N+TT PSSGF N GAG+ASG  NF G  SG +N A+++ G SGF N G+L SG 
Sbjct  2911  PAPGFFNATTGPSSGFLNWGAGSASGLLNF-GNNSGLYNFATSSMGNSGFQNYGSLQSGW  2969

Query  572   ANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVG  631
             AN+GN+ISG+YNT    L  PA  SGLL+  +GT        N+ G    G     F+VG
Sbjct  2970  ANLGNSISGIYNTG---LGAPANVSGLLN--IGT--------NLAGWLQNGPTETTFSVG  3016

Query  632   LANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIG  691
             LANLG +N+G  N+G  NLG A+ G YN+G AN G  NLG AN GD N+G ANIGS+NIG
Sbjct  3017  LANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGSANIGSSNIG  3076

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGN  751
              G  G G      L +   NIG  N+G+GNIG+ N+G+GN G GN GTGNWGIGNSG  N
Sbjct  3077  FGNVGPG------LTAAIGNIGFGNTGNGNIGIGNTGTGNIGFGNTGTGNWGIGNSGDYN  3130

Query  752   FGIGNAGSTNTGLF----------NSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYN  801
              GIGN GSTN+G F          NSGD NTG  N G+ NTGS N G  NTGGFN GNYN
Sbjct  3131  TGIGNTGSTNSGFFNTGLVNTGIGNSGDYNTGLFNAGNTNTGSFNPGDYNTGGFNPGNYN  3190

Query  802   TGYF----------NTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQPGSDRPRHRRR  851
             TGYF          N+GD+         Y +  F     Q     A +   S+ P    R
Sbjct  3191  TGYFNPGNSNTGIANSGDVNTGAFNSGNYSNGFFWRGDYQGLGGFAYQSAVSEIPWSYDR  3250

Query  852   HSR  854
                
Sbjct  3251  FQH  3253


 Score =  244 bits (624),  Expect = 5e-62, Method: Compositional matrix adjust.
 Identities = 182/377 (49%), Positives = 214/377 (57%), Gaps = 74/377 (19%)

Query  510  IPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGS  569
            I  +PGF NST++PSSGFFN+GAG+ASGF N G   SGF+N +S   G SG  N G L S
Sbjct  428  IFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAIGNSGLANAGVLVS  487

Query  570  GVANVGNTISGLYNTSTSNLATPAFNSGLLHHSV-------GTMTLNFGLAN--------  614
            GV N GNT+SGL+N S   + TPA  SG  +          G    N GLAN        
Sbjct  488  GVINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFNLGLANRGVVNILG  547

Query  615  ------------------------------------VGGNNVGGANAGIFNVGLANLGDY  638
                                                VG  N+G  N G+FNVG  +LG+Y
Sbjct  548  NANIGNYNILGSGNVGDFNILGSGNLGSQNILGSGNVGSFNIGSGNIGVFNVGSGSLGNY  607

Query  639  NIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSG  698
            NIG GNLG  N+GF + G YN+GF N G  N GFANTG+NNIGFAN G+NNIGIGL+G  
Sbjct  608  NIGSGNLGIYNIGFGNVGDYNVGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDN  667

Query  699  QIGF---GSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIG  755
            Q GF      NSG+ N GLFNSG  N+G+FN+G+GN GI N+GTGNWGIGN G  N GI 
Sbjct  668  QQGFNIASGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGIANSGTGNWGIGNPGTDNTGIL  727

Query  756  NAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAG-----------------  798
            NAGS NTG+ N+GD NTG  N GSYNTG  N G+ NTG FN G                 
Sbjct  728  NAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGNFNVGDTNTGSYNPGDTNTGFF  787

Query  799  ---NYNTGYFNTGDLQH  812
               N NTG F+TGD  +
Sbjct  788  NPGNVNTGAFDTGDFNN  804


 Score =  216 bits (551),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 147/271 (55%), Positives = 186/271 (69%), Gaps = 18/271 (6%)

Query  173   KKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGF  232
               ++GL    T+ A      P+   F++GLAN+G  N+G+ N+G +N+G  N+G YNLG 
Sbjct  2988  ANVSGLLNIGTNLAGWLQNGPTETTFSVGLANLGFWNLGSANIGNYNLGSANIGVYNLGS  3047

Query  233   ANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGN-GQIGFGSFNSGSHN  291
             AN+G  NLG AN+G  N+G AN GS+N+GFGN     VG GLT   G IGFG  N+G+ N
Sbjct  3048  ANIGDFNLGSANIGDFNLGSANIGSSNIGFGN-----VGPGLTAAIGNIGFG--NTGNGN  3100

Query  292   IGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG----------DVN  341
             IG+ N+G+GN+G  N+GTGN+GIGNSG  N G+GNTGSTN+G+FNTG          D N
Sbjct  3101  IGIGNTGTGNIGFGNTGTGNWGIGNSGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYN  3160

Query  342   TGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYS  401
             TG FN G+ NTG+FN G+YNTG FN GNYNTGYFN G+ NTG+AN+G+VNTGAF +GNYS
Sbjct  3161  TGLFNAGNTNTGSFNPGDYNTGGFNPGNYNTGYFNPGNSNTGIANSGDVNTGAFNSGNYS  3220

Query  402   NGVLWRGDYQGLIGADIALEIPAIPINAQLF  432
             NG  WRGDYQGL G      +  IP +   F
Sbjct  3221  NGFFWRGDYQGLGGFAYQSAVSEIPWSYDRF  3251


 Score =  204 bits (520),  Expect = 5e-50, Method: Compositional matrix adjust.
 Identities = 185/402 (47%), Positives = 216/402 (54%), Gaps = 99/402 (24%)

Query  506   PLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVG  565
             P    PA PGFGNSTT PSSGFFN+G G++SGFGN G   SGFWN A A  G SG  N G
Sbjct  2312  PATGHPAGPGFGNSTTGPSSGFFNSGTGSSSGFGNVGANNSGFWNTAFAGIGNSGLQNFG  2371

Query  566   ALGSGVANVGNTISGLYNTSTSNLATPA-----------------------FNSGLL---  599
             +L SG AN+GNT+SG YNTS ++ ATPA                       FN+GL    
Sbjct  2372  SLQSGWANLGNTVSGFYNTSAADFATPANLSGLSNVGADLTGVLRGPNGSTFNAGLANLG  2431

Query  600   HHSVGTMTL-------------NFGLANVGGNNVGGANAGIFNVGLANLGD------YNI  640
               +VG+  L             N G  N+G  N+GGAN G FNVG+AN G        NI
Sbjct  2432  QFNVGSANLGSANLGSANLGNSNVGFGNIGNANIGGANIGDFNVGIANTGPGLTAAVNNI  2491

Query  641   GFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFA-----------------  683
             G GN G  N+G  + G+YNIGF NTG+NN+G   +GDN IGF                  
Sbjct  2492  GIGNTGNYNIGVGNTGNYNIGFGNTGNNNIGIGLSGDNQIGFGPLNAGIANMGLFNLGDN  2551

Query  684   -------------------------NIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSG  718
                                      N G+NN+GIGLTG G  GF SLNSG+ N G FNSG
Sbjct  2552  NFGMANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGFFNSG  2611

Query  719   DGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIG------------NAGSTNTGLFN  766
               N GLFNSG+GN G+ N+GTGN GIGN G G FG+G            N+GS N GLFN
Sbjct  2612  TANTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDSQVGIGGTNSGSFNIGLFN  2671

Query  767   SGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
             SG  N G  N G+ N G  NTG+ NTG  N+GNYNTG  N G
Sbjct  2672  SGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNAG  2713


 Score =  142 bits (358),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 125/301 (42%), Positives = 168/301 (56%), Gaps = 38/301 (12%)

Query  139   AYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAG-  197
             + +  WA     + G++  ++A  +        L  L+ +   LT       G    AG 
Sbjct  2372  SLQSGWANLGNTVSGFYNTSAADFAT----PANLSGLSNVGADLTGVLRGPNGSTFNAGL  2427

Query  198   -----FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGS---------------  237
                  FN+G AN+G+ N+G+ N+G  NVGFGN+G+ N+G AN+G                
Sbjct  2428  ANLGQFNVGSANLGSANLGSANLGNSNVGFGNIGNANIGGANIGDFNVGIANTGPGLTAA  2487

Query  238   -DNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFN  296
              +N+G+ N G +NIG  NTG+ N+GFGNTG+NN+GIGL+G+ QIGFG  N+G  N+GLFN
Sbjct  2488  VNNIGIGNTGNYNIGVGNTGNYNIGFGNTGNNNIGIGLSGDNQIGFGPLNAGIANMGLFN  2547

Query  297   SGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTG--GFNPGSYNTGN  354
              G  N G+ N+G  N GI N+G  N GL NTG+ N G   TGD  +G    N G+ NTG 
Sbjct  2548  LGDNNFGMANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGF  2607

Query  355   FNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLI  414
             FN+G  NTG FN+G  NTG FN+G  N G+   GN+ TG F       GV   GD Q  I
Sbjct  2608  FNSGTANTGLFNSGTGNTGLFNSGTGNVGI---GNMGTGGF-------GVGLSGDSQVGI  2657

Query  415   G  415
             G
Sbjct  2658  G  2658


 Score =  139 bits (351),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 109/184 (60%), Positives = 123/184 (67%), Gaps = 17/184 (9%)

Query  633  ANLGDYNIGFGNLGGDNLGFAHAGS------YNIGFANTGSNNLGFANTGDNNIGFANIG  686
            AN+G+ NIG GN+G  N+GF + G        NIGF NTGSNN+GF NTG NNIGF N  
Sbjct  220  ANIGNGNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFGN--  277

Query  687  SNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGN  746
                    TG G  G G   SG    G  NSG GNIGLFNSG+GN GIGN+GTGNWGIGN
Sbjct  278  --------TGDGNRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGN  329

Query  747  SG-AGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYF  805
            SG + N G GN+G  NTG FNSG  NTG  N G+YNTGS N G+ NTGGFN G YNTGY 
Sbjct  330  SGNSYNTGFGNSGDANTGFFNSGIANTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGYL  389

Query  806  NTGD  809
            N+G+
Sbjct  390  NSGN  393


 Score = 62.8 bits (151),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 57/138 (42%), Positives = 75/138 (55%), Gaps = 2/138 (1%)

Query  177   GLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLG  236
             G    L+  +    G  ++  FN+GL N G  NVG GN G  NVG GN G+ N G  N G
Sbjct  2644  GFGVGLSGDSQVGIGGTNSGSFNIGLFNSGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSG  2703

Query  237   SDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFN  296
             + N GL N G  N G AN G++N G  N G+ N GI     G    GS+N+GS+N G+ N
Sbjct  2704  NYNTGLLNAGLVNTGIANPGNHNTGLFNIGTFNTGI--ANPGHYNTGSYNTGSYNTGMAN  2761

Query  297   SGSGNVGLFNSGTGNFGI  314
             +G    G F +G+ N G+
Sbjct  2762  AGDYGTGAFITGSMNNGL  2779


 Score = 62.0 bits (149),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 75/186 (41%), Positives = 91/186 (49%), Gaps = 35/186 (18%)

Query  235   LGSD-------------NLGLANLGGHNIGFANTGSNNVGFGNT------------GSNN  269
             +G++             N GL N G    G+AN G+   GF NT            G +N
Sbjct  2347  VGANNSGFWNTAFAGIGNSGLQNFGSLQSGWANLGNTVSGFYNTSAADFATPANLSGLSN  2406

Query  270   VGIGLTG-----NGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGL  324
             VG  LTG     NG     +FN+G  N+G FN GS N+G  N G+ N G  N G GN G 
Sbjct  2407  VGADLTGVLRGPNGS----TFNAGLANLGQFNVGSANLGSANLGSANLGNSNVGFGNIGN  2462

Query  325   GNTGSTNTGWFNTGDVNTG-GFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTG  383
              N G  N G FN G  NTG G      N G  NTGNYN G  N GNYN G+ NTG+ N G
Sbjct  2463  ANIGGANIGDFNVGIANTGPGLTAAVNNIGIGNTGNYNIGVGNTGNYNIGFGNTGNNNIG  2522

Query  384   VANTGN  389
             +  +G+
Sbjct  2523  IGLSGD  2528


 Score = 57.8 bits (138),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 103/272 (38%), Positives = 133/272 (49%), Gaps = 38/272 (13%)

Query  571  VANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM--TLNFGLANVGGNNVGGANAGIF  628
              N+     GL+N+ T N+     NSG  +  +G    + N G  N G  N G  N+GI 
Sbjct  302  TGNI-----GLFNSGTGNVGIG--NSGTGNWGIGNSGNSYNTGFGNSGDANTGFFNSGIA  354

Query  629  NVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSN  688
            N G+ N G+YN G  N G  N G  + G YN G+ N+G+ N G AN+G+ N G    G+ 
Sbjct  355  NTGVGNAGNYNTGSYNPGNSNTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGAFITGNF  414

Query  689  NIGIGLTGSGQ-IGFGS---LNSGSH-NIGLFNSGDGNI-GLFNSGSGNFGIGNAGT---  739
            N G    G  Q + FGS    NS S  + G FNSG G+  G  NSG+ N G  N+ +   
Sbjct  415  NNGFLWRGDHQGLIFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAI  474

Query  740  GNWGIGNSGAGNFGIGNAGSTNTGLFN------------SGDLNTGSL------NPGSYN  781
            GN G+ N+G    G+ N+G+T +GLFN            SG  NTGS        P  +N
Sbjct  475  GNSGLANAGVLVSGVINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFN  534

Query  782  TGSVNTGSVNT-GGFNAGNYNT-GYFNTGDLQ  811
             G  N G VN  G  N GNYN  G  N GD  
Sbjct  535  LGLANRGVVNILGNANIGNYNILGSGNVGDFN  566


 Score = 52.0 bits (123),  Expect = 5e-04, Method: Compositional matrix adjust.
 Identities = 81/237 (35%), Positives = 106/237 (45%), Gaps = 52/237 (21%)

Query  220   VGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNT------------GS  267
             VG  N G +N  FA +G  N GL N G    G+AN G+   GF NT            G 
Sbjct  2347  VGANNSGFWNTAFAGIG--NSGLQNFGSLQSGWANLGNTVSGFYNTSAADFATPANLSGL  2404

Query  268   NNVGIGLTG-----NGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNF  322
             +NVG  LTG     NG     +FN+G  N+G FN GS N+G               + N 
Sbjct  2405  SNVGADLTGVLRGPNGS----TFNAGLANLGQFNVGSANLG---------------SANL  2445

Query  323   GLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNT  382
             G  N G++N G+ N G+ N GG N G +N G  NTG   T + N              N 
Sbjct  2446  GSANLGNSNVGFGNIGNANIGGANIGDFNVGIANTGPGLTAAVN--------------NI  2491

Query  383   GVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQV  439
             G+ NTGN N G    GNY+ G    G+    IG     +I   P+NA + +M +  +
Sbjct  2492  GIGNTGNYNIGVGNTGNYNIGFGNTGNNNIGIGLSGDNQIGFGPLNAGIANMGLFNL  2548


 Score = 47.8 bits (112),  Expect = 0.010, Method: Compositional matrix adjust.
 Identities = 65/165 (40%), Positives = 79/165 (48%), Gaps = 20/165 (12%)

Query  671   GFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIG-----LFNSGDG---NI  722
             G AN G N  GF N+ ++        SG   +GSL SG  N+G     +FN+G G   N+
Sbjct  1393  GIANIGANISGFQNVANSAT------SGFNNYGSLQSGLANLGDTVSGVFNTGIGAPANV  1446

Query  723   -GLFNSGSGNFGI-GNAGTG----NWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLN  776
              G+FN GS   G   +  TG    N G+GN G  N G  N G +N GL N G  N GS N
Sbjct  1447  SGMFNIGSNLAGFFHDQATGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLGSGN  1506

Query  777   PGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
              GS+N    N GS N G  N GNYN G  N G      G    + 
Sbjct  1507  LGSFNVFGGNQGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDFN  1551


 Score = 46.2 bits (108),  Expect = 0.027, Method: Compositional matrix adjust.
 Identities = 65/176 (37%), Positives = 72/176 (41%), Gaps = 45/176 (25%)

Query  675   TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIG---------------------  713
              G NN GF N     IG     SG   FGSL SG  N+G                     
Sbjct  2347  VGANNSGFWNTAFAGIG----NSGLQNFGSLQSGWANLGNTVSGFYNTSAADFATPANLS  2402

Query  714   -------------------LFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGI  754
                                 FN+G  N+G FN GS N G  N G+ N G  N G GN G 
Sbjct  2403  GLSNVGADLTGVLRGPNGSTFNAGLANLGQFNVGSANLGSANLGSANLGNSNVGFGNIGN  2462

Query  755   GNAGSTNTGLFNSGDLNTG-SLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGD  809
              N G  N G FN G  NTG  L     N G  NTG+ N G  N GNYN G+ NTG+
Sbjct  2463  ANIGGANIGDFNVGIANTGPGLTAAVNNIGIGNTGNYNIGVGNTGNYNIGFGNTGN  2518


>gi|183984588|ref|YP_001852879.1| PPE family protein [Mycobacterium marinum M]
 gi|183177914|gb|ACC43024.1| PPE family protein [Mycobacterium marinum M]
Length=3006

 Score =  559 bits (1440),  Expect = 9e-157, Method: Compositional matrix adjust.
 Identities = 439/909 (49%), Positives = 545/909 (60%), Gaps = 117/909 (12%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M F VS PE+NS R++ GAGSGP+L+AAAAWDGLA EL  AA+ F SVTS L  ++W+GP
Sbjct  1    MSFSVSPPEINSARIFSGAGSGPLLSAAAAWDGLAGELGSAAATFSSVTSALTGSSWQGP  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            A+ AMA   + YLGWL S   QA QAA+QAR+A A FEA  AATVHP  V ANR  LVSL
Sbjct  61   ASAAMANVASGYLGWLASTGVQAGQAASQARIAAAAFEATVAATVHPVAVLANRTQLVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            V+SNLLGFNAPAIA  EA YE+MWAQDVAAM GYH GASAAV+AL PFTQ L+  A  + 
Sbjct  121  VTSNLLGFNAPAIATVEAEYEQMWAQDVAAMFGYHTGASAAVAALTPFTQVLQSPAAAAA  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGANNVG-----------------------------  211
             + +A     G  +   FN GL N+G  NVG                             
Sbjct  181  AVQTAIIDFPGRTNI--FNAGLGNLGVGNVGFASVGDGNVGGGNLGDGNVGFGNVGGLNF  238

Query  212  -NGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNV  270
             +GN G FN+G GN+GSYN G  NLGS N+G  N G +N+GF N+G  N+GFGN+GSNN+
Sbjct  239  GSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFGNAGDYNVGFGNSGLGNIGFGNSGSNNL  298

Query  271  GIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGST  330
            GIGLTG+GQ+GFG +NSGS N+GLFNSG GNVGLFNSGTGN+G+GNSG  + GL N G  
Sbjct  299  GIGLTGSGQVGFGGWNSGSGNVGLFNSGVGNVGLFNSGTGNWGVGNSGEFDTGLFNAGRY  358

Query  331  NTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNV  390
            NTG FN+G +NTG  N G YN+G+FNTG  NTG  NAG+ NTG+ NTG+ NTG  N+G++
Sbjct  359  NTGVFNSGVLNTGVGNAGDYNSGSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSGHL  418

Query  391  NTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQL---FSMPI----------H  437
            NTG F  G+ +NG  WRGD QG IG D  + IP I +   +    ++P+           
Sbjct  419  NTGGFNQGSQNNGFFWRGDAQGQIGFDYTITIPEIGLGLNVDVPLNIPLRGTIGTLIDGE  478

Query  438  QVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLT  497
             ++ +PG   TIP + L  T++   +   GP+ +   T+T P V + VGGP  ++   L+
Sbjct  479  PIISVPG--FTIPALHLDGTALSGTI---GPIVVDPITITGPQVDLMVGGPGESLQLALS  533

Query  498  GM-VGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATS  556
            G  VG V IP+  +PA  GFGN+T++PSSG F      +S      GG SG+WN AS   
Sbjct  534  GPGVGPVVIPVAHVPAVAGFGNTTSAPSSG-FFNSGTGSSSGFGNVGGGSGWWNFASGGV  592

Query  557  GLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVG  616
            G SG GNVGALGSGV N+G+ +SG  NT       P+  SG+                  
Sbjct  593  GYSGVGNVGALGSGVFNLGDGVSGWVNT------IPSMGSGV------------------  628

Query  617  GNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS---------  667
              NVG   AG+F+ G   +  + +G  N GG N+G A+ G  N+G AN GS         
Sbjct  629  -GNVGDGLAGLFSQGADKISVFGLGVANHGGLNVGSANVGDANLGSANVGSANVGGGNVG  687

Query  668  ---------------------NNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLN  706
                                  N+G ANTGD N G+ N G  NIG G TG G  GFG+  
Sbjct  688  GGNVGVANVGDGNVGGANVGGANVGGANTGDGNWGWGNTGGGNIGWGNTGVGNFGFGNQG  747

Query  707  SGSHNIGL----------FNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGN  756
            SG+  IGL          +NSG GN+GLFNSG GN G  N+G+GN+GI NSG+ N GI N
Sbjct  748  SGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNFGIANSGSFNTGIAN  807

Query  757  AGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGE  816
            AG TNTG FNSG  NTG  N G+YN+G  N G+ NTG FN G+ NTG+FNTGD     G 
Sbjct  808  AGLTNTGWFNSGLANTGWGNAGAYNSGGFNAGAYNTGSFNPGHVNTGWFNTGDTNTGLGN  867

Query  817  HRQYQHRRF  825
                    F
Sbjct  868  SGNINTGAF  876


 Score =  428 bits (1100),  Expect = 3e-117, Method: Compositional matrix adjust.
 Identities = 318/728 (44%), Positives = 403/728 (56%), Gaps = 102/728 (14%)

Query  259   NVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSG  318
             N GFGN GS N+GIGL+G+ Q+GFG +NSGS N+GLFNSG GN+G FNSG+GNFGI NSG
Sbjct  1677  NFGFGNQGSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNFGIANSG  1736

Query  319   TGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTG  378
             + N G+ N G TNTGWFN+G  NTG  N G+YN+G FN G YNTGSFN G+ NTG+FNTG
Sbjct  1737  SFNTGIANAGLTNTGWFNSGLANTGWGNAGAYNSGGFNAGAYNTGSFNPGHVNTGWFNTG  1796

Query  379   DYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINA---QLFSMP  435
             D NTG+ N+GN+NTGAF++G+ +NG  WRG  QGLIGAD  + IP IPI      +  +P
Sbjct  1797  DTNTGLGNSGNINTGAFVSGDMNNGFFWRGTGQGLIGADYTITIPHIPITVGGGGILKLP  1856

Query  436   ----IHQVMVMP------------------------GSVMTIPGMRLPFTSIVPFVVYYG  467
                 I  + V P                         + + IPG  L F      V    
Sbjct  1857  LTGEISNLKVEPFGLRGEGGGGIPLIAHFTLLGDTKATTIDIPGTSLSFELPSLPVAIKV  1916

Query  468   PVELPQSTLTLPTVTI--------TVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNS  519
              +    S ++ P +TI         +G   T  D ++ G +  +++ +  +   PGFGNS
Sbjct  1917  DINDELSVISTPEITINPITFNEFVIGSDETPFDVSIDGGIEPLTVTVFHLSPTPGFGNS  1976

Query  520   TTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTIS  579
               +PSSGFFN+G G  SGFGNFG   SG+ N+AS     SGF N G+  SG  NVG+ +S
Sbjct  1977  GGAPSSGFFNSGDG-VSGFGNFGATVSGWGNVASHA---SGFENFGSGLSGFTNVGDVLS  2032

Query  580   GLYNTSTSNLATPAFN------SGLLHHSVGTMTL-NFGLANVGGNNVGGAN--------  624
             GL NT++S L T          SGL +     M++ N GL N+G  NVG A+        
Sbjct  2033  GLKNTNSSGLGTSGVGNVGDSLSGLFYAGPDRMSIFNAGLGNLGVGNVGFASVGDGNVGG  2092

Query  625   ------------AGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGF  672
                          G  N G  N G +N+G GN+G  N G  + GSYNIGF N G  N+GF
Sbjct  2093  GNLGDGNVGFGNVGGLNFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFGNAGDYNVGF  2152

Query  673   ANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNF  732
              N+G  NIGF N GSNN+GIGLTGSGQ+GFG  NSGS N+GLFNSGDGN+GLFNS     
Sbjct  2153  GNSGLGNIGFGNSGSNNLGIGLTGSGQVGFGGWNSGSGNVGLFNSGDGNVGLFNS-----  2207

Query  733   GIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNT  792
                  GTGNWG+GNSG  + G+ NAG  NTG+FNSG LNTG  N G YN+GS NTG+ NT
Sbjct  2208  -----GTGNWGVGNSGEFDTGLFNAGRYNTGVFNSGVLNTGVGNAGDYNSGSFNTGASNT  2262

Query  793   GGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRH  852
             G  NAG+ NTG+ NTG+L    G         F+  Q  Q      R             
Sbjct  2263  GDLNAGDTNTGWANTGNLNTGFGNSGHLNTGGFN--QGSQNNGFFWRG------------  2308

Query  853   SRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYR--PLH-RPSDT  909
                 D + +  +  + T      G  +Q        S H    R   +   P+H  P D 
Sbjct  2309  ----DAQGQIGFDYTITIPEIAVGFNVQVPL-DIPLSGHLGEIRLSEFMLPPIHLNPVDG  2363

Query  910   DNRSHTCG  917
             ++ + T G
Sbjct  2364  NSLTGTIG  2371


 Score =  416 bits (1069),  Expect = 1e-113, Method: Compositional matrix adjust.
 Identities = 316/696 (46%), Positives = 393/696 (57%), Gaps = 106/696 (15%)

Query  259   NVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSG  318
             N GFGN GS N+GIGL+G+ Q+GFG +NSGS N+GLFNSG GN+G FNSG+GNFGI NSG
Sbjct  740   NFGFGNQGSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNFGIANSG  799

Query  319   TGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTG  378
             + N G+ N G TNTGWFN+G  NTG  N G+YN+G FN G YNTGSFN G+ NTG+FNTG
Sbjct  800   SFNTGIANAGLTNTGWFNSGLANTGWGNAGAYNSGGFNAGAYNTGSFNPGHVNTGWFNTG  859

Query  379   DYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPIN---AQLFSMP  435
             D NTG+ N+GN+NTGAF++G+ +NG  WRG  QGLIGAD  + IP IP+      + ++P
Sbjct  860   DTNTGLGNSGNINTGAFVSGDMNNGFFWRGTGQGLIGADYTITIPQIPLTIGGGGILNIP  919

Query  436   IHQVM----VMPGSV-------MTIPGMRLPFTSIVPFVVYYG-PVELPQ---STLTLPT  480
             I   +    V P +V         IP + L  T +       G  V +P+     +T+P 
Sbjct  920   ITGAITGLTVQPFTVHGVGTSTTGIP-LDLQVTILGADTNEIGVDVHIPKPIDKDVTVPI  978

Query  481   VTITVGGPTTTIDGNLTGMV-------------------------------GGVSIPLIK  509
              +I V     TID  +  +V                               G V+IP+  
Sbjct  979   PSIPVLNLGVTIDNEIGAIVAPEIAINPINFNKFMIGNEDSPLTVHIGGGAGPVTIPVFH  1038

Query  510   IPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGS  569
             +   PGFGNS  +PSSGFFN+G G  SGFGNFG   SG+ N+AS     SGF N G   S
Sbjct  1039  LSPTPGFGNSGGAPSSGFFNSGDG-VSGFGNFGATVSGWGNVASHA---SGFENFGTGLS  1094

Query  570   GVANVGNTISGLYNTSTSNLATPAFN------SGLLHHSVGTMTL-NFGLANVGGNNVGG  622
             G  NVG+ +SGL NT++S L T          SGL +     M++ N GL N+G  NVG 
Sbjct  1095  GFTNVGDALSGLKNTNSSGLGTSGVGNVGDSLSGLFYAGPDRMSIFNAGLGNLGVGNVGF  1154

Query  623   AN--------------------AGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGF  662
             A+                     G  N G  N G +N+G GN+G  N G  + GSYNIGF
Sbjct  1155  ASVGDGNVGGGNLGDGNVGFGNVGGLNFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGF  1214

Query  663   ANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNI  722
              N G  N+GF N+G  NIGF N GSNN+GIGLTGSGQ+GFG  NSGS N+GLFNSG GN+
Sbjct  1215  GNAGDYNVGFGNSGLGNIGFGNSGSNNLGIGLTGSGQVGFGGWNSGSGNVGLFNSGVGNV  1274

Query  723   GLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNT  782
             GLFNS          GTGNWG+GNSG  + G+ NAG  NTG+FNSG LNTG  N G YN+
Sbjct  1275  GLFNS----------GTGNWGVGNSGEFDTGLFNAGRYNTGVFNSGVLNTGVGNAGDYNS  1324

Query  783   GSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGE---------HRQYQHRRFHLRQPQQR  833
             GS NTG+ NTG  NAG+ NTG+ NTG+L    G          ++  Q+  F  R   Q 
Sbjct  1325  GSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSGHLNTGGFNQGSQNNGFFWRGDAQ-  1383

Query  834   PSVAGRQPGSDRPRHRRRHSRNPDCERRREYPDSHT  869
                   Q G D          N D       P + T
Sbjct  1384  -----GQIGFDYTLTVPEIGLNIDANIPINIPVAAT  1414


 Score =  395 bits (1016),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 319/706 (46%), Positives = 403/706 (58%), Gaps = 110/706 (15%)

Query  209   NVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSN  268
             N G+GN G FN+G GN+GSYN G  NLGS N+G  N G +N+GF N+G  N+GFGN+GSN
Sbjct  2109  NFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFGNAGDYNVGFGNSGLGNIGFGNSGSN  2168

Query  269   NVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTG  328
             N+GIGLTG+GQ+GFG +NSGS N+GLFNSG GNVGLFNSGTGN+G+GNSG  + GL N G
Sbjct  2169  NLGIGLTGSGQVGFGGWNSGSGNVGLFNSGDGNVGLFNSGTGNWGVGNSGEFDTGLFNAG  2228

Query  329   STNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG  388
               NTG FN+G +NTG  N G YN+G+FNTG  NTG  NAG+ NTG+ NTG+ NTG  N+G
Sbjct  2229  RYNTGVFNSGVLNTGVGNAGDYNSGSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSG  2288

Query  389   NVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPA------------IPINAQLFSMPI  436
             ++NTG F  G+ +NG  WRGD QG IG D  + IP             IP++  L  + +
Sbjct  2289  HLNTGGFNQGSQNNGFFWRGDAQGQIGFDYTITIPEIAVGFNVQVPLDIPLSGHLGEIRL  2348

Query  437   HQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNL  496
              + M+ P  +  + G  L  T         GP+ +   T+T P V + VGGP  ++   L
Sbjct  2349  SEFMLPPIHLNPVDGNSLTGT--------IGPIVVDPITITGPQVDLMVGGPGESLQLAL  2400

Query  497   TGM-VGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASAT  555
             +G  VG V IP+  +PA  GFGN+T++PSSG F      +S      GG SG+WN AS  
Sbjct  2401  SGPGVGPVVIPVAHVPAVAGFGNTTSAPSSG-FFNSGTGSSSGFGNVGGGSGWWNFASGG  2459

Query  556   SGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANV  615
              G SG GNVGALGSGV N+G+ +SG  NT       P+  SG+                 
Sbjct  2460  VGYSGVGNVGALGSGVFNLGDGVSGWVNT------IPSMGSGV-----------------  2496

Query  616   GGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS--------  667
                NVG   AG+F+ G   +  + +G  N GG N+G A+ G  N+G AN GS        
Sbjct  2497  --GNVGDGLAGLFSQGADKISVFGLGVANHGGLNVGSANVGDANLGSANVGSANVGGGNV  2554

Query  668   --NNLGFANTGDN----------------------------------------NIGFANI  685
                N+G AN GD                                         N GF N 
Sbjct  2555  GDGNVGVANVGDGNVGGANVGGANVGGANTGDGNWGWGNTGGGNIGWGNTGVGNFGFGNQ  2614

Query  686   GSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIG  745
             GS NIGIGL+G  Q+GFG  NSGS N+GLFNSGDGNIG FNSGSGNFGI N+G+ N GI 
Sbjct  2615  GSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNFGIANSGSFNTGIA  2674

Query  746   ----------NSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGF  795
                       NSG  N G GNAG+ N+G FN+G  NTGS NPG  NTG  NTG +NTG  
Sbjct  2675  NAGLTNTGWFNSGLANTGWGNAGAYNSGGFNAGAYNTGSFNPGHVNTGWFNTGDINTGLG  2734

Query  796   NAGNYNTGYFNTGDLQH---RHGEHRQYQHRRFHLRQPQQRPSVAG  838
             N+GN NTG F +GD+ +     G  +      + +  PQ   ++ G
Sbjct  2735  NSGNINTGAFVSGDMNNGFFWRGTGQGLIGADYTITIPQIPLTIGG  2780


 Score =  395 bits (1014),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 319/698 (46%), Positives = 403/698 (58%), Gaps = 97/698 (13%)

Query  209   NVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSN  268
             N G+GN G FN+G GN+GSYN G  NLGS N+G  N G +N+GF N+G  N+GFGN+GSN
Sbjct  1181  NFGSGNWGGFNLGSGNIGSYNFGPGNLGSYNIGFGNAGDYNVGFGNSGLGNIGFGNSGSN  1240

Query  269   NVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTG  328
             N+GIGLTG+GQ+GFG +NSGS N+GLFNSG GNVGLFNSGTGN+G+GNSG  + GL N G
Sbjct  1241  NLGIGLTGSGQVGFGGWNSGSGNVGLFNSGVGNVGLFNSGTGNWGVGNSGEFDTGLFNAG  1300

Query  329   STNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTG  388
               NTG FN+G +NTG  N G YN+G+FNTG  NTG  NAG+ NTG+ NTG+ NTG  N+G
Sbjct  1301  RYNTGVFNSGVLNTGVGNAGDYNSGSFNTGASNTGDLNAGDTNTGWANTGNLNTGFGNSG  1360

Query  389   NVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQL---FSMPIHQVM-VMPG  444
             ++NTG F  G+ +NG  WRGD QG IG D  L +P I +N       ++P+   + V+  
Sbjct  1361  HLNTGGFNQGSQNNGFFWRGDAQGQIGFDYTLTVPEIGLNIDANIPINIPVAATLGVIKV  1420

Query  445   SVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGM-VGGV  503
                TIP + L   ++   +   GP+ +   T+T P V + VGGP  ++   L+G  VG V
Sbjct  1421  GTFTIPTLYLNGNNLTGTI---GPIVVDPITITGPQVDLMVGGPGESLQLALSGPGVGPV  1477

Query  504   SIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGN  563
              IP+  +PA  GFGN+T++PSSG F      +S      GG SG+WN AS   G SG GN
Sbjct  1478  VIPVAHVPAVAGFGNTTSAPSSG-FFNSGTGSSSGFGNVGGGSGWWNFASGGVGYSGVGN  1536

Query  564   VGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGA  623
             VGALGSGV N+G+ +SG  NT       P+  SG+                    NVG  
Sbjct  1537  VGALGSGVFNLGDGVSGWVNT------IPSMGSGV-------------------GNVGDG  1571

Query  624   NAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGS----------NNLGFA  673
              AG+F+ G   +  + +G  N GG N+G A+ G  N+G AN GS           N+G A
Sbjct  1572  LAGLFSQGADKISVFGLGVANHGGLNVGSANVGDANLGSANVGSANVGGGNVGDGNVGVA  1631

Query  674   NTGDN----------------------------------------NIGFANIGSNNIGIG  693
             N GD                                         N GF N GS NIGIG
Sbjct  1632  NVGDGNVGGANVGGANVGGANTGDGNWGWGNTGGGNIGWGNTGVGNFGFGNQGSGNIGIG  1691

Query  694   LTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIG--------  745
             L+G  Q+GFG  NSGS N+GLFNSGDGNIG FNSGSGNFGI N+G+ N GI         
Sbjct  1692  LSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNFGIANSGSFNTGIANAGLTNTG  1751

Query  746   --NSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTG  803
               NSG  N G GNAG+ N+G FN+G  NTGS NPG  NTG  NTG  NTG  N+GN NTG
Sbjct  1752  WFNSGLANTGWGNAGAYNSGGFNAGAYNTGSFNPGHVNTGWFNTGDTNTGLGNSGNINTG  1811

Query  804   YFNTGDLQH---RHGEHRQYQHRRFHLRQPQQRPSVAG  838
              F +GD+ +     G  +      + +  P    +V G
Sbjct  1812  AFVSGDMNNGFFWRGTGQGLIGADYTITIPHIPITVGG  1849


 Score =  277 bits (709),  Expect = 6e-72, Method: Compositional matrix adjust.
 Identities = 176/384 (46%), Positives = 234/384 (61%), Gaps = 46/384 (11%)

Query  259   NVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSG  318
             N GFGN GS N+GIGL+G+ Q+GFG +NSGS N+GLFNSG GN+G FNSG+GNFGI NSG
Sbjct  2608  NFGFGNQGSGNIGIGLSGDHQVGFGGWNSGSGNVGLFNSGDGNIGFFNSGSGNFGIANSG  2667

Query  319   TGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTG  378
             + N G+ N G TNTGWFN+G  NTG  N G+YN+G FN G YNTGSFN G+ NTG+FNTG
Sbjct  2668  SFNTGIANAGLTNTGWFNSGLANTGWGNAGAYNSGGFNAGAYNTGSFNPGHVNTGWFNTG  2727

Query  379   DYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIP------------  426
             D NTG+ N+GN+NTGAF++G+ +NG  WRG  QGLIGAD  + IP IP            
Sbjct  2728  DINTGLGNSGNINTGAFVSGDMNNGFFWRGTGQGLIGADYTITIPQIPLTIGGGGILNIP  2787

Query  427   -------INAQLFS----------MPIHQVMVMPGS------VMTIPGMR---------L  454
                    +  Q F+          +P++  + + G        + IP            L
Sbjct  2788  ITGAITGLTVQSFTVHGVGSAATPIPVNLHLNVDGESGGATVSVHIPNTDVSFDVHVDGL  2847

Query  455   PFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAP  514
             P T  +P      P+ +P   ++   + +++G  +T+++  +   +G +SIP++ +P AP
Sbjct  2848  PITLDLPLDSEVRPIVVPDIPISRIPIVLSLGSDSTSLNTAIGAGIGPISIPILDLPTAP  2907

Query  515   GFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANV  574
             GFGN+T SPSSGFFN+G G  SGFGN G   SG WN  S  SGL  +G  G+L SG+ N+
Sbjct  2908  GFGNATDSPSSGFFNSGPGGVSGFGNVGDTLSGVWNFGSYASGLQNYG--GSLLSGITNL  2965

Query  575   GNTISGLYNTSTSNLATPAFNSGL  598
             G   SG+ NTS   LA     SG+
Sbjct  2966  GGATSGVGNTSDLGLAIAGVISGI  2989


 Score =  100 bits (248),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 96/202 (48%), Positives = 116/202 (58%), Gaps = 14/202 (6%)

Query  627  IFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIG  686
            IFN GL NLG  N+GF ++G  N+G  + G  N+GF N G  N G  N G  N+G  NIG
Sbjct  195  IFNAGLGNLGVGNVGFASVGDGNVGGGNLGDGNVGFGNVGGLNFGSGNWGGFNLGSGNIG  254

Query  687  SNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGN  746
            S N            FG  N GS+NIG  N+GD N+G  NSG GN G GN+G+ N GIG 
Sbjct  255  SYN------------FGPGNLGSYNIGFGNAGDYNVGFGNSGLGNIGFGNSGSNNLGIGL  302

Query  747  SGAGNFGIG--NAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGY  804
            +G+G  G G  N+GS N GLFNSG  N G  N G+ N G  N+G  +TG FNAG YNTG 
Sbjct  303  TGSGQVGFGGWNSGSGNVGLFNSGVGNVGLFNSGTGNWGVGNSGEFDTGLFNAGRYNTGV  362

Query  805  FNTGDLQHRHGEHRQYQHRRFH  826
            FN+G L    G    Y    F+
Sbjct  363  FNSGVLNTGVGNAGDYNSGSFN  384


>gi|340625385|ref|YP_004743837.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340003575|emb|CCC42696.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=3507

 Score =  556 bits (1433),  Expect = 7e-156, Method: Compositional matrix adjust.
 Identities = 392/767 (52%), Positives = 472/767 (62%), Gaps = 102/767 (13%)

Query  162   VSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVG  221
             V+ +  F   L  +   +   ++   + AG  +  GFNLG  N+G+ NV  GN G +NVG
Sbjct  1464  VTGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGGFNLGSGNLGSFNVFGGNQGSYNVG  1523

Query  222   FGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIG  281
               NLG+YN+G +NLGS N G +N G  N+GFANTGSNN+GF NTG+NN+GIGL+GN Q G
Sbjct  1524  PANLGNYNIGLSNLGSYNFGFSNAGDFNLGFANTGSNNIGFANTGNNNIGIGLSGNNQQG  1583

Query  282   F---GSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG  338
             F   G +NSGS N GLFNSG+ N+GLFNSGTGN GIGNSGTGN+G+GN G  NTG FN+G
Sbjct  1584  FNFAGGWNSGSGNSGLFNSGTNNIGLFNSGTGNIGIGNSGTGNWGIGNPGIDNTGLFNSG  1643

Query  339   DVNTGGFNPGSYNTGNFNTGNYNTGSFNAG----------NYNTGYFNTGDYNTGVANTG  388
             D+NTG  N G+ NTG  NTG+YNTGSFNAG          NYNTGY NTG YNTG+AN+G
Sbjct  1644  DINTGLLNAGNVNTGVGNTGHYNTGSFNAGSFNTAGLNPGNYNTGYLNTGSYNTGLANSG  1703

Query  389   NVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIP--AIPINAQLFSMPIHQVMVMPGSV  446
             +VNTGA IAGNYSNG LWRGDYQGL+G    + +P  AIP+N ++   PI   + + G++
Sbjct  1704  DVNTGALIAGNYSNGFLWRGDYQGLVGIGQTITVPDTAIPVNLRV---PIFLDIPVTGTL  1760

Query  447   --MTIPGMRLP------FTSIVPF-VVYYGPVELPQSTLTLPTVTITVG-GPTTTIDGNL  496
                T+ G R P      F   +PF          P  ++ LP + I +G GP   ID   
Sbjct  1761  GTFTVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNISIVLPNIGINLGTGPDPLIDIAG  1820

Query  497   TGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATS  556
             TG +  + IPLI IPAAPGFGNSTT+PSSGFFN+G GT SGFGN G  +SGF+NL S +S
Sbjct  1821  TGGLLPIKIPLIDIPAAPGFGNSTTTPSSGFFNSGTGTVSGFGNVGSNSSGFFNLTSGSS  1880

Query  557   GLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMT---------  607
             G+SG  N G L SG  N GNT+SGL N ST  L+ PA  SG    +VG M          
Sbjct  1881  GISGVQNFGELVSGGFNFGNTVSGLVNASTLGLSMPANLSG--GGNVGAMVAGFVNNTQI  1938

Query  608   LNFGLANVGGNNVGGANAGIFNVGLANLGD--------------------YNIGFGNLGG  647
             LN G  NVG  NVG  N G  NVGL NLG+                    YNIG  NLG 
Sbjct  1939  LNLGFGNVGSGNVGHGNIGDSNVGLGNLGNSNVGHGNIGSFNVFSGNRGSYNIGPANLGN  1998

Query  648   DNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNS  707
              N+G  + GSYN GF N G  NLGFAN+G NNIGFAN G+NNIGIGL+G  Q GFGS NS
Sbjct  1999  YNIGLGNLGSYNFGFGNAGDFNLGFANSGSNNIGFANTGNNNIGIGLSGDNQQGFGSWNS  2058

Query  708   GSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAG---------  758
             G+ N GLFNSG  NIGLFNSG+GN GIGN+GTGN GIGN G GN G+GN+G         
Sbjct  2059  GTANTGLFNSGTNNIGLFNSGTGNIGIGNSGTGNTGIGNPGFGNTGLGNSGTGNWGLWNP  2118

Query  759   ---------------------STNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNA  797
                                  STNTG+ N G  NTGS N GS NTGS N G  NTG +N 
Sbjct  2119  GTGNMGVANVGTYNTGGYNVGSTNTGIANVGIANTGSYNTGSTNTGSFNDGDFNTGFYNT  2178

Query  798   GNYNTGYFNTGDL--------QHRHGEHRQYQHR-----RFHLRQPQ  831
             G+YNTG++NTGD+           +G   Q  H+      + +  PQ
Sbjct  2179  GDYNTGFYNTGDVNTGAFIGGNFSNGAFWQSDHQGQWGAYYAITVPQ  2225


 Score =  542 bits (1397),  Expect = 9e-152, Method: Compositional matrix adjust.
 Identities = 360/704 (52%), Positives = 454/704 (65%), Gaps = 46/704 (6%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             FN+G  N+G  NVG+G++G +N+G GNLG YN+GF N+G  N+G  N G  N GFANTG+
Sbjct  587   FNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNVGDYNVGFGNAGDFNQGFANTGN  646

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGF-------------GSFNSGSHNIGLFNSGSGNVGL  304
             NN+GF NTG+NN+GIGL+G+ Q GF             G FNSG++N+G+FN+G+GNVG+
Sbjct  647   NNIGFANTGNNNIGIGLSGDNQQGFNIASGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGI  706

Query  305   FNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGS  364
              NSGTGN+GIGN GT N G+ N GS NTG+ N GD NTG +N GSYNTG++N GN NTG+
Sbjct  707   ANSGTGNWGIGNPGTENTGILNAGSYNTGFLNAGDFNTGFYNTGSYNTGSYNVGNTNTGN  766

Query  365   FNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPA  424
             FN G+ NTG +N GD NTG  N GNVNTGAF  G+++NG L  GD  G I  D+++  P 
Sbjct  767   FNVGDTNTGSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNHGQIAIDLSVTTPF  826

Query  425   IPINAQLFSMPIHQVMVMPGSVMTI--PGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVT  482
             IPIN Q+  + +H VM   G+++T+       P T  +  + ++GPV L  STLT+PT+T
Sbjct  827   IPINEQMV-IDVHNVMTFGGNMITVTEDSTVFPRTFYLSGLFFFGPVNLSASTLTVPTIT  885

Query  483   ITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFG  542
             +T+GGPT T+  ++ G +   +I  +KI  APG GNSTT+PSSGFFN+G G  SGF N G
Sbjct  886   LTIGGPTVTVPISIVGALESRTITFLKIDPAPGIGNSTTNPSSGFFNSGTGGTSGFQNVG  945

Query  543   GGASGFWN--LASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL--  598
             GG+SG WN  L+SA  G SGF N+G+L SG AN+GN++SG +NTST NL+TPA  SGL  
Sbjct  946   GGSSGVWNSGLSSAI-GNSGFQNLGSLQSGWANLGNSVSGFFNTSTVNLSTPANVSGLNN  1004

Query  599   --------LHHSVGTM---------TLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIG  641
                          GT+          LN G AN+G  N+G  N G FNV   N G YN+G
Sbjct  1005  IGTNLSGVFRGPTGTIFNAGIANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYNVG  1064

Query  642   FGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIG  701
               NLG  N+GFA+ G+YNIGF N G  N GFANTG+NNIGFAN G+NNIGIGL+G  Q G
Sbjct  1065  PANLGNYNIGFANLGNYNIGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQG  1124

Query  702   FGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTN  761
             F       +  G +NSG  NIGLFNSG+ N GIGN+GTGNWGIGNSG+GN GIGN GSTN
Sbjct  1125  F-------NFAGGWNSGTNNIGLFNSGTNNVGIGNSGTGNWGIGNSGSGNTGIGNTGSTN  1177

Query  762   TGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQ  821
             TG FN+G +NTG  N G+YNTG  NTG  NTG  N G++NTG++NTG+            
Sbjct  1178  TGFFNTGIVNTGVANAGNYNTGWYNTGDTNTGIANLGDFNTGFYNTGNFSTGFANQGDIA  1237

Query  822   HRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYP  865
                F            G Q G     +R      P      E P
Sbjct  1238  TGAFITGDMGNGAFWRGDQQGLFSAGYRVHVPEIP-AHVTVEVP  1280


 Score =  504 bits (1299),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 349/659 (53%), Positives = 436/659 (67%), Gaps = 54/659 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             FNLG  NVG+ NV +GN G +NVG  NLG+YN+GFANLG+ N+G  N G  N GFANTG+
Sbjct  1041  FNLGSGNVGSFNVFSGNQGSYNVGPANLGNYNIGFANLGNYNIGFGNAGDFNQGFANTGN  1100

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGF---GSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGI  314
             NN+GF NTG+NN+GIGL+G+ Q GF   G +NSG++NIGLFNSG+ NVG+ NSGTGN+GI
Sbjct  1101  NNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGTNNIGLFNSGTNNVGIGNSGTGNWGI  1160

Query  315   GNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGY  374
             GNSG+GN G+GNTGSTNTG+FNTG VNTG  N G+YNTG +NTG+ NTG  N G++NTG+
Sbjct  1161  GNSGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGNYNTGWYNTGDTNTGIANLGDFNTGF  1220

Query  375   FNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSM  434
             +NTG+++TG AN G++ TGAFI G+  NG  WRGD QGL  A   + +P IP +  +  +
Sbjct  1221  YNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQGLFSAGYRVHVPEIPAHVTV-EV  1279

Query  435   PIHQVMVMPG-----SVMTIPGMRLPFT-SIVPFVVYYGPVE---LPQSTLTLPTVTITV  485
             PI+  +         S +T+  +   FT  I    +  G +    LP  T T P +T+ +
Sbjct  1280  PINIPITASFTNTVYSGITLEQINFGFTIDIAGIPLLAGAISKAVLPPITGTGPQITVNI  1339

Query  486   GGP--TTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGG  543
             G P  +T I    T  VG   +  + IPA  GF N+TT PSSGFFN G GT SG  N G 
Sbjct  1340  GDPGGSTAIRIPATASVGPFDVTFVNIPATTGFFNATTDPSSGFFNGGPGTVSGIANIGA  1399

Query  544   GASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPA-----FN---  595
               SGF N+A++ +  SGF N G+L SG+AN+G+T+SG++NT+   +  PA     FN   
Sbjct  1400  NISGFQNVANSAT--SGFNNYGSLQSGLANLGDTVSGVFNTA---IGAPANVSGMFNVGS  1454

Query  596   --SGLLHHSVGTMTL---------------------NFGLANVGGNNVGGANAGIFNVGL  632
               +G  H  V  M++                     N GLAN+GG N+G  N G FNV  
Sbjct  1455  NLAGFFHDQVTGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGGFNLGSGNLGSFNVFG  1514

Query  633   ANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGI  692
              N G YN+G  NLG  N+G ++ GSYN GF+N G  NLGFANTG NNIGFAN G+NNIGI
Sbjct  1515  GNQGSYNVGPANLGNYNIGLSNLGSYNFGFSNAGDFNLGFANTGSNNIGFANTGNNNIGI  1574

Query  693   GLTGSGQIGF---GSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGA  749
             GL+G+ Q GF   G  NSGS N GLFNSG  NIGLFNSG+GN GIGN+GTGNWGIGN G 
Sbjct  1575  GLSGNNQQGFNFAGGWNSGSGNSGLFNSGTNNIGLFNSGTGNIGIGNSGTGNWGIGNPGI  1634

Query  750   GNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
              N G+ N+G  NTGL N+G++NTG  N G YNTGS N GS NT G N GNYNTGY NTG
Sbjct  1635  DNTGLFNSGDINTGLLNAGNVNTGVGNTGHYNTGSFNAGSFNTAGLNPGNYNTGYLNTG  1693


 Score =  474 bits (1220),  Expect = 3e-131, Method: Compositional matrix adjust.
 Identities = 359/754 (48%), Positives = 450/754 (60%), Gaps = 144/754 (19%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHN---------  249
             N+GL N+G +NVG+GN+G FNV  GN GSYN+G ANLG+ N+GL NLG +N         
Sbjct  1960  NVGLGNLGNSNVGHGNIGSFNVFSGNRGSYNIGPANLGNYNIGLGNLGSYNFGFGNAGDF  2019

Query  250   -IGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSG  308
              +GFAN+GSNN+GF NTG+NN+GIGL+G+ Q GFGS+NSG+ N GLFNSG+ N+GLFNSG
Sbjct  2020  NLGFANSGSNNIGFANTGNNNIGIGLSGDNQQGFGSWNSGTANTGLFNSGTNNIGLFNSG  2079

Query  309   TGNFGIGNSGTGNFGLGN------------------------------TGSTNTGWFNTG  338
             TGN GIGNSGTGN G+GN                               G+ NTG +N G
Sbjct  2080  TGNIGIGNSGTGNTGIGNPGFGNTGLGNSGTGNWGLWNPGTGNMGVANVGTYNTGGYNVG  2139

Query  339   DVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAG  398
               NTG  N G  NTG++NTG+ NTGSFN G++NTG++NTGDYNTG  NTG+VNTGAFI G
Sbjct  2140  STNTGIANVGIANTGSYNTGSTNTGSFNDGDFNTGFYNTGDYNTGFYNTGDVNTGAFIGG  2199

Query  399   NYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTS  458
             N+SNG  W+ D+QG  GA  A+ +P IP+     ++P++  + +    + + G ++P  +
Sbjct  2200  NFSNGAFWQSDHQGQWGAYYAITVPQIPLLNFSLNIPVNIPIHLDLGTLAVNGFQIPAIT  2259

Query  459   IVPFVVYY---GPVELPQSTLTLPTVTITVGGP--TTTIDGNLTGMVGGVSIPLIKIPAA  513
             +    V +   GP+ +P+   TLP + I +G P  +T+I   +T   G V IPL+ IP A
Sbjct  2260  LRALGVTHFSVGPIIVPRIAGTLPVIDINIGDPGGSTSIPITITSGAGPVVIPLLDIPPA  2319

Query  514   PGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVAN  573
             PGFGNSTT PSSGFFN+G G++SGFGN G   SGFWN A A  G SG  N G+L SG AN
Sbjct  2320  PGFGNSTTGPSSGFFNSGTGSSSGFGNLGANNSGFWNTAFAGIGNSGLQNFGSLQSGWAN  2379

Query  574   VGNTISGLYNTSTSNLATPA-----------------------FNSGLL---HHSVGTMT  607
             +GNT+SG YNTST++LATPA                       FN+GL      +VG+  
Sbjct  2380  LGNTVSGFYNTSTADLATPANVSGLSNIGADLTGVLRGPSGSIFNAGLANLGQFNVGSAN  2439

Query  608   L-------------NFGLANVGGNNVGGANAGIFNVGLANLGD------YNIGFGNLGGD  648
             L             N G  N+G  N+GGAN G FNVG+AN G        NIG GN G  
Sbjct  2440  LGSANLGSANLGNSNVGFGNIGHANIGGANIGDFNVGIANAGPGLTTAVNNIGIGNTGNY  2499

Query  649   NLGFAHAGSYNIGFANTGSNNL--------------------------------------  670
             N+G  + G YNIGF NTG+NN+                                      
Sbjct  2500  NIGMGNTGDYNIGFGNTGNNNIGIGLTGDNQIGFGPLNAGIANMGLFNLGDNNFGLANAG  2559

Query  671   ----GFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFN  726
                 G ANTG+NNIG  N G+NN+GIGLTG G  GF SLNSG+ N G FNSG  N GLFN
Sbjct  2560  NFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGFFNSGTANTGLFN  2619

Query  727   SGSGNFGIGNAGTGNWGIGNSGAGNFGIG------------NAGSTNTGLFNSGDLNTGS  774
             SG+GN G+ N+GTGN GIGN G G FG+G            N+GS N GLFNSG  N G 
Sbjct  2620  SGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDNQVGIGGTNSGSFNIGLFNSGTGNVGI  2679

Query  775   LNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTG  808
              N G+ N G  NTG+ NTG  N+GNYNTG+ N+G
Sbjct  2680  GNSGTGNVGIGNTGTGNTGIGNSGNYNTGWLNSG  2713


 Score =  456 bits (1173),  Expect = 9e-126, Method: Compositional matrix adjust.
 Identities = 353/805 (44%), Positives = 449/805 (56%), Gaps = 93/805 (11%)

Query  191   GPPSAAGFNLGLANVGANNVGNGNVGVFNVGFG------------NLGSYNLGFANLGSD  238
             G  +A  FN G+AN G NN+G  N G  NVG G            N G+ N GF N G+ 
Sbjct  2554  GLANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGFFNSGTA  2613

Query  239   NLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSG  298
             N GL N G  N G  N+G+ NVG GN G+   G+GL+G+ Q+G G  NSGS NIGLFNSG
Sbjct  2614  NTGLFNSGTGNTGLFNSGTGNVGIGNMGTGGFGVGLSGDNQVGIGGTNSGSFNIGLFNSG  2673

Query  299   SGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTG  358
             +GNVG+ NSGTGN GIGN+GTGN G+GN+G+ NTGW N+G  NTG  NPG++NTG FN G
Sbjct  2674  TGNVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGWLNSGLFNTGIANPGNHNTGLFNIG  2733

Query  359   NYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGAD-  417
              +NTG  N G+YNTG +NTG YNTG+AN G+  TGAFI G+ +NG+LWR D QGL+ A+ 
Sbjct  2734  AFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAFITGSMNNGLLWRADRQGLLAANY  2793

Query  418   -IALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSI---VPFVVYYGPVELPQ  473
              I +E PA  +N  +   P++  +    + ++IP +  P       V   +  G V  P 
Sbjct  2794  TITIERPAAFLNVDI---PVNIPITGDITNVSIPAITFPRIDASGSVDIGILSGTVLAPV  2850

Query  474   STLTL--------------------PTVTITVGGPTTTIDGNLTGMVGG--VSIPLIKIP  511
               +TL                    P + + +G P  +   N+ G  G   +SIP+I + 
Sbjct  2851  GPITLHGGDASAPLDTPIEIDFGPSPAINLNIGKPDGSTVINIVGGAGAGPISIPIIDLR  2910

Query  512   AAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGV  571
              APGF N+TT PSSGF N GAG+ASG  NF G  SG  N A+ + G SGF N G+L SG 
Sbjct  2911  PAPGFFNATTGPSSGFLNWGAGSASGLLNF-GNNSGLVNFATTSMGNSGFQNYGSLQSGW  2969

Query  572   ANVGNTISGLYNTSTSNLATPAFNSGLLH-----------------HSVGTMTL---NFG  611
             AN+GN+ISG+YNT    L  PA  SGLL+                  SVG   L   N G
Sbjct  2970  ANLGNSISGIYNTG---LGAPANVSGLLNIGANLAGWLQNGPTETTFSVGLANLGFWNLG  3026

Query  612   LANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSY-------------  658
              AN+G  N+G AN G++N+G AN+GD+N+G  N+G  NLG A+ GS              
Sbjct  3027  SANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGSANIGSSNIGFGNVGPGLTA  3086

Query  659   ---NIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLF  715
                NIGF NTG+ N+GF NTG  NIGF N G+ NIGIGLTG    GFG  NSG+ NIGLF
Sbjct  3087  AIGNIGFGNTGNGNIGFGNTGTGNIGFGNTGNGNIGIGLTGDTMTGFGGWNSGTGNIGLF  3146

Query  716   NSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAG----------NFGIGNAGSTNTGLF  765
             NSG GNIG  NSG+GN+GIGN+G  N GIGN+G+           N GIGN+G  NTGLF
Sbjct  3147  NSGTGNIGFGNSGTGNWGIGNSGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNTGLF  3206

Query  766   NSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRF  825
             NSG  NTGS NPG YNTG  N G+ NTG FN GN NTG+ N+GD+         Y +  F
Sbjct  3207  NSGSTNTGSFNPGDYNTGGFNPGNYNTGYFNPGNSNTGFANSGDVNTGAFNSGNYSNGFF  3266

Query  826   HLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSS  885
                  Q     A +   S+ P      S   +     +      D   +    I      
Sbjct  3267  WRGDYQGLGGFAYQSAVSEIPWSYDIGSH-IEIPIEGDINAITQDAFTIDEFEIPIKLRV  3325

Query  886   TEHSRHCYFFRTRRYRPLHRPSDTD  910
             +    +  F    ++  +  P  T+
Sbjct  3326  SVCVIYIPFKGCVKHVSVTIPITTE  3350


 Score =  379 bits (973),  Expect = 2e-102, Method: Compositional matrix adjust.
 Identities = 270/440 (62%), Positives = 317/440 (73%), Gaps = 38/440 (8%)

Query  1    MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGP  60
            M F V  PE+NS R+Y+GAG  PML AAAAWDGLADEL  AA+ F +VT+GLA ++W G 
Sbjct  1    MSFAVLPPEINSARLYVGAGLAPMLDAAAAWDGLADELGSAAASFSAVTAGLAGSSWLGA  60

Query  61   AAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSL  120
            A+ AM  A APYLGWL +A AQA+QAA Q R+A A FEAA AATVHPAI++ANRA+ VSL
Sbjct  61   ASTAMTGATAPYLGWLRAAAAQAQQAATQTRLAAAAFEAALAATVHPAIISANRALFVSL  120

Query  121  VSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSE  180
            V SNLLG NAPAIAATEAAYE+MWAQDVAAM GYHAGASAAVSAL PF+Q L  +AG   
Sbjct  121  VVSNLLGQNAPAIAATEAAYEQMWAQDVAAMFGYHAGASAAVSALTPFSQALPTVAGGGA  180

Query  181  RLTSAAAAAAGPPSAAGFNLGLANVGAN---------------NVGNGNVGVFNVGFGNL  225
             +++AAA      +    NLGLANVG                 N+GNGN+G      GN+
Sbjct  181  LVSAAAAQVT---TRVFRNLGLANVGEGNVGNGNVGNFNLGSANIGNGNIGS-----GNI  232

Query  226  GSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQ------  279
            GS N+GF N+G       N    NIGF NTGSNN+GFGNTGSNN+G G TG+G       
Sbjct  233  GSSNIGFGNVGPGLTAALN----NIGFGNTGSNNIGFGNTGSNNIGFGNTGDGNRGIGLT  288

Query  280  ----IGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTG-NFGLGNTGSTNTGW  334
                +GFG  NSG+ NIGLFNSG+GNVG+ NSGTGN+GIGNSG   N G GN+G  NTG+
Sbjct  289  GSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGNSYNTGFGNSGDANTGF  348

Query  335  FNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGA  394
            FN+G  NTG  N G YNTG++N GN NTG FN G YNTGY N+G+YNTG+AN+GNVNTGA
Sbjct  349  FNSGIANTGVGNAGDYNTGSYNPGNSNTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGA  408

Query  395  FIAGNYSNGVLWRGDYQGLI  414
            FI GN++NG LWRGD+QGLI
Sbjct  409  FITGNFNNGFLWRGDHQGLI  428


 Score =  310 bits (794),  Expect = 8e-82, Method: Compositional matrix adjust.
 Identities = 240/532 (46%), Positives = 300/532 (57%), Gaps = 71/532 (13%)

Query  139   AYERMWAQ---DVAAMVGYHAGASAAVSALMPFTQQLKKLA--GLSERLTSAAAAAAG--  191
             + +  WA     ++ +     GA A VS L+     L      G +E   S   A  G  
Sbjct  2964  SLQSGWANLGNSISGIYNTGLGAPANVSGLLNIGANLAGWLQNGPTETTFSVGLANLGFW  3023

Query  192   ---PPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLG--  246
                  +   +NLG AN+G  N+G+ N+G FN+G  N+G +NLG AN+GS N+G  N+G  
Sbjct  3024  NLGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGSANIGSSNIGFGNVGPG  3083

Query  247   --------------GHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNI  292
                             NIGF NTG+ N+GFGNTG+ N+GIGLTG+   GFG +NSG+ NI
Sbjct  3084  LTAAIGNIGFGNTGNGNIGFGNTGTGNIGFGNTGNGNIGIGLTGDTMTGFGGWNSGTGNI  3143

Query  293   GLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTG----------DVNT  342
             GLFNSG+GN+G  NSGTGN+GIGNSG  N G+GNTGSTN+G+FNTG          D NT
Sbjct  3144  GLFNSGTGNIGFGNSGTGNWGIGNSGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNT  3203

Query  343   GGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSN  402
             G FN GS NTG+FN G+YNTG FN GNYNTGYFN G+ NTG AN+G+VNTGAF +GNYSN
Sbjct  3204  GLFNSGSTNTGSFNPGDYNTGGFNPGNYNTGYFNPGNSNTGFANSGDVNTGAFNSGNYSN  3263

Query  403   GVLWRGDYQGLIGADIALEIPAIPINAQL---FSMPIH-QVMVMPGSVMTIPGMRLPFTS  458
             G  WRGDYQGL G      +  IP +  +     +PI   +  +     TI    +P   
Sbjct  3264  GFFWRGDYQGLGGFAYQSAVSEIPWSYDIGSHIEIPIEGDINAITQDAFTIDEFEIPIKL  3323

Query  459   IVPFVVYYGPVE--LPQSTLTLPTVTITVG---------GPTTTIDGNLT--------GM  499
              V   V Y P +  +   ++T+P  T  +G          P   ID   T        G 
Sbjct  3324  RVSVCVIYIPFKGCVKHVSVTIPITTEHLGPYEIDASTINPDQPIDTAFTQTLDFAGSGT  3383

Query  500   VGGVSIPL-IKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGA-SGFWNLASATSG  557
             VG  + P       +PGF NSTT PSSGFFN+GAG ASGF N    A SG  N+ + TSG
Sbjct  3384  VG--AFPFGFGWQQSPGFFNSTTIPSSGFFNSGAGGASGFLNDAAAAVSGLGNVFTETSG  3441

Query  558   L--------SGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHH  601
                      SGF N G L SG AN+GNT+SGLYNTS  +LAT A  SG  +H
Sbjct  3442  FFNAGGVGNSGFQNFGNLLSGWANLGNTVSGLYNTSMLDLATQALISGFGNH  3493


 Score =  248 bits (634),  Expect = 3e-63, Method: Compositional matrix adjust.
 Identities = 197/474 (42%), Positives = 238/474 (51%), Gaps = 97/474 (20%)

Query  510  IPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGS  569
            I  +PGF NST++PSSGFFN+GAG+ASGF N G   SGF+N +S   G SG  N G L S
Sbjct  428  IFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAIGNSGLANAGVLVS  487

Query  570  GVANVGNTISGLYNTSTSNLATPAFNSGLLHHSV-------GTMTLNFGLAN--------  614
            GV N GNT+SGL+N S   + TPA  SG  +          G    N GLAN        
Sbjct  488  GVINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFNLGLANRGVVNILG  547

Query  615  ------------------------------------VGGNNVGGANAGIFNVGLANLGDY  638
                                                VG  N+G  N G+FNVG  +LG+Y
Sbjct  548  NANIGNYNILGSGNVGDFNILGSGNLGSQNILGSGNVGSFNIGSGNIGVFNVGSGSLGNY  607

Query  639  NIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSG  698
            NIG GNLG  N+GF + G YN+GF N G  N GFANTG+NNIGFAN G+NNIGIGL+G  
Sbjct  608  NIGSGNLGIYNIGFGNVGDYNVGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDN  667

Query  699  QIGF---GSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIG  755
            Q GF      NSG+ N GLFNSG  N+G+FN+G+GN GI N+GTGNWGIGN G  N GI 
Sbjct  668  QQGFNIASGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGIANSGTGNWGIGNPGTENTGIL  727

Query  756  NAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAG-----------------  798
            NAGS NTG  N+GD NTG  N GSYNTGS N G+ NTG FN G                 
Sbjct  728  NAGSYNTGFLNAGDFNTGFYNTGSYNTGSYNVGNTNTGNFNVGDTNTGSYNPGDTNTGFF  787

Query  799  ---NYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRN  855
               N NTG F+TGD  +         H +  +      P +                   
Sbjct  788  NPGNVNTGAFDTGDFNNGFLVAGD-NHGQIAIDLSVTTPFI-------------------  827

Query  856  PDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYRPLHRPSDT  909
            P  E+     D H +     G+ I     ST   R  Y      + P++  + T
Sbjct  828  PINEQMVI--DVH-NVMTFGGNMITVTEDSTVFPRTFYLSGLFFFGPVNLSAST  878


 Score =  145 bits (365),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 126/301 (42%), Positives = 168/301 (56%), Gaps = 38/301 (12%)

Query  139   AYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAG-  197
             + +  WA     + G++  ++A ++        +  L+ +   LT      +G    AG 
Sbjct  2372  SLQSGWANLGNTVSGFYNTSTADLAT----PANVSGLSNIGADLTGVLRGPSGSIFNAGL  2427

Query  198   -----FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGS---------------  237
                  FN+G AN+G+ N+G+ N+G  NVGFGN+G  N+G AN+G                
Sbjct  2428  ANLGQFNVGSANLGSANLGSANLGNSNVGFGNIGHANIGGANIGDFNVGIANAGPGLTTA  2487

Query  238   -DNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFN  296
              +N+G+ N G +NIG  NTG  N+GFGNTG+NN+GIGLTG+ QIGFG  N+G  N+GLFN
Sbjct  2488  VNNIGIGNTGNYNIGMGNTGDYNIGFGNTGNNNIGIGLTGDNQIGFGPLNAGIANMGLFN  2547

Query  297   SGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTG--GFNPGSYNTGN  354
              G  N GL N+G  N GI N+G  N GL NTG+ N G   TGD  +G    N G+ NTG 
Sbjct  2548  LGDNNFGLANAGNFNQGIANTGNNNIGLFNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGF  2607

Query  355   FNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLI  414
             FN+G  NTG FN+G  NTG FN+G  N G+   GN+ TG F       GV   GD Q  I
Sbjct  2608  FNSGTANTGLFNSGTGNTGLFNSGTGNVGI---GNMGTGGF-------GVGLSGDNQVGI  2657

Query  415   G  415
             G
Sbjct  2658  G  2658


 Score =  140 bits (352),  Expect = 1e-30, Method: Compositional matrix adjust.
 Identities = 109/184 (60%), Positives = 122/184 (67%), Gaps = 17/184 (9%)

Query  633  ANLGDYNIGFGNLGGDNLGFAHAGS------YNIGFANTGSNNLGFANTGDNNIGFANIG  686
            AN+G+ NIG GN+G  N+GF + G        NIGF NTGSNN+GF NTG NNIGF N  
Sbjct  220  ANIGNGNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFGN--  277

Query  687  SNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGN  746
                    TG G  G G   SG    G  NSG GNIGLFNSG+GN GIGN+GTGNWGIGN
Sbjct  278  --------TGDGNRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGN  329

Query  747  SG-AGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYF  805
            SG + N G GN+G  NTG FNSG  NTG  N G YNTGS N G+ NTGGFN G YNTGY 
Sbjct  330  SGNSYNTGFGNSGDANTGFFNSGIANTGVGNAGDYNTGSYNPGNSNTGGFNMGQYNTGYL  389

Query  806  NTGD  809
            N+G+
Sbjct  390  NSGN  393


 Score =  109 bits (272),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 96/227 (43%), Positives = 121/227 (54%), Gaps = 49/227 (21%)

Query  613  ANVGGNNVGGANAGIFNVGLANLGD------YNIGFGNLGGDNLGFAHAGSYNIGFANTG  666
            AN+G  N+G  N G  N+G  N+G        NIGFGN G +N+GF + GS NIGF NTG
Sbjct  220  ANIGNGNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIGFGNTG  279

Query  667  ----------------------SNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGS  704
                                  + N+G  N+G  N+G  N G+ N GIG +G+       
Sbjct  280  DGNRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGNWGIGNSGN-------  332

Query  705  LNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGL  764
                S+N G  NSGD N G FNSG  N G+GNAG  N        G++   N G++NTG 
Sbjct  333  ----SYNTGFGNSGDANTGFFNSGIANTGVGNAGDYN-------TGSY---NPGNSNTGG  378

Query  765  FNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQ  811
            FN G  NTG LN G+YNTG  N+G+VNTG F  GN+N G+   GD Q
Sbjct  379  FNMGQYNTGYLNSGNYNTGLANSGNVNTGAFITGNFNNGFLWRGDHQ  425


 Score = 60.1 bits (144),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 104/272 (39%), Positives = 133/272 (49%), Gaps = 38/272 (13%)

Query  571  VANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTM--TLNFGLANVGGNNVGGANAGIF  628
              N+     GL+N+ T N+     NSG  +  +G    + N G  N G  N G  N+GI 
Sbjct  302  TGNI-----GLFNSGTGNVGIG--NSGTGNWGIGNSGNSYNTGFGNSGDANTGFFNSGIA  354

Query  629  NVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSN  688
            N G+ N GDYN G  N G  N G  + G YN G+ N+G+ N G AN+G+ N G    G+ 
Sbjct  355  NTGVGNAGDYNTGSYNPGNSNTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGAFITGNF  414

Query  689  NIGIGLTGSGQ-IGFGS---LNSGSH-NIGLFNSGDGNI-GLFNSGSGNFGIGNAGT---  739
            N G    G  Q + FGS    NS S  + G FNSG G+  G  NSG+ N G  N+ +   
Sbjct  415  NNGFLWRGDHQGLIFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAI  474

Query  740  GNWGIGNSGAGNFGIGNAGSTNTGLFN------------SGDLNTGSL------NPGSYN  781
            GN G+ N+G    G+ N+G+T +GLFN            SG  NTGS        P  +N
Sbjct  475  GNSGLANAGVLVSGVINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMSGFFGGPPVFN  534

Query  782  TGSVNTGSVNT-GGFNAGNYNT-GYFNTGDLQ  811
             G  N G VN  G  N GNYN  G  N GD  
Sbjct  535  LGLANRGVVNILGNANIGNYNILGSGNVGDFN  566


 Score = 59.3 bits (142),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 56/138 (41%), Positives = 73/138 (53%), Gaps = 2/138 (1%)

Query  177   GLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLG  236
             G    L+       G  ++  FN+GL N G  NVG GN G  NVG GN G+ N G  N G
Sbjct  2644  GFGVGLSGDNQVGIGGTNSGSFNIGLFNSGTGNVGIGNSGTGNVGIGNTGTGNTGIGNSG  2703

Query  237   SDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFN  296
             + N G  N G  N G AN G++N G  N G+ N GI     G    GS+N+GS+N G+ N
Sbjct  2704  NYNTGWLNSGLFNTGIANPGNHNTGLFNIGAFNTGI--ANPGHYNTGSYNTGSYNTGMAN  2761

Query  297   SGSGNVGLFNSGTGNFGI  314
             +G    G F +G+ N G+
Sbjct  2762  AGDYGTGAFITGSMNNGL  2779


>gi|240173413|ref|ZP_04752071.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=1060

 Score =  552 bits (1423),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 374/787 (48%), Positives = 476/787 (61%), Gaps = 83/787 (10%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
              N+G  N+G  N+G GNVG +NVG  NLGSYN+G  N G++N GL N G  N GF N G 
Sbjct  244   LNVGSGNIGLYNLGPGNVGNYNVGSANLGSYNVGLGNFGANNFGLGNFGDFNTGFGNAGD  303

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNS  317
              N+G GN+G+ N+GIGLTG GQ+GFG+ NSGS N GLFNSG+ N+GLFNSGTGN GI NS
Sbjct  304   ANIGIGNSGTGNIGIGLTGTGQVGFGALNSGSGNSGLFNSGTNNIGLFNSGTGNVGIANS  363

Query  318   GTGNFGLGNTGSTNTGWFNTGD----------VNTGGFNPGSYNTGNFNTGNYNTGSFNA  367
             GTGN+G+GN+G  NTG  N GD          VNTG FN G YN+G+FN G++NT  FNA
Sbjct  364   GTGNWGIGNSGHINTGLLNAGDINTGLINAGNVNTGIFNAGGYNSGSFNAGSFNTLGFNA  423

Query  368   GNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPI  427
             GNYNTGY NTGDYNTG+AN+G+V+TGAF  G+YSNGVLWRGDYQGL+  D  + IP   I
Sbjct  424   GNYNTGYLNTGDYNTGLANSGDVDTGAFNLGSYSNGVLWRGDYQGLVAIDYEIVIPDTAI  483

Query  428   NAQL-FSMPIHQVMVMPGSVMTIPGMRLP-FTSIVPFV-------VYYGPVELPQSTLTL  478
              A L   +P +         + +    LP +T+ V  +       V  GP+ +P   + L
Sbjct  484   PAYLDLQVPANLPFSATLGTLVLDSFTLPKYTADVKILGFLKFEAVSVGPITIPNIYIDL  543

Query  479   PTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGF  538
             P++  T+G P++ +  +  G +G + IP++ IPAAPGFGNSTT PSSGFFN G G++SG 
Sbjct  544   PSIAGTLGSPSSVLQLSGPGSIGPIRIPIVHIPAAPGFGNSTTVPSSGFFNTGNGSSSGI  603

Query  539   GNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGL  598
             GN G   SGFWN AS  SG+SG+ N+G L SGV+N GNTISG  NT+T++LATPA  SG+
Sbjct  604   GNVGANLSGFWNAASGGSGISGYKNLGDLTSGVSNFGNTISGFLNTATASLATPADVSGI  663

Query  599   ----LHHS---VGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLG  651
                  H S    G   +N G AN G  NVG  N G +N+G  N+G  N+GFGN G  N+G
Sbjct  664   GNTGSHISGLFNGLSNINIGFANHGDVNVGSGNDGSYNLGSGNVGSDNVGFGNFGDGNIG  723

Query  652   FAHAGSYNIGFANTGSNN--------------------LGFANTGDNNIGFANIGSNNIG  691
               + GS N+G  N GS+N                    +GF N G+ NIG  N GSNNIG
Sbjct  724   SGNWGSGNVGPGNWGSHNTGLGNLGANNAGLGNLGDFNVGFGNAGNANIGLGNTGSNNIG  783

Query  692   IGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGN  751
             IGLTG+GQ+GFG+LNSGS N GLFNSG  N+GLFNSG+GN GIGN+GTGN+GIGN+G  N
Sbjct  784   IGLTGNGQVGFGALNSGSGNSGLFNSGSNNVGLFNSGTGNVGIGNSGTGNFGIGNAGTAN  843

Query  752   FGIG--------------------NAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVN  791
              GIG                    N GS NTG FN+GD+N+G+ NPG YN+GS NTG+ N
Sbjct  844   TGIGNPGIGNWGYGNPGNYNTGIANTGSVNTGFFNTGDVNSGTANPGDYNSGSYNTGNTN  903

Query  792   TGGFNAGNYNTGYFNTGDLQH--------RHGEHRQYQHRRFHLRQPQQRPSVAGRQPGS  843
             TG  N G+YNTG+FN+GD             G      +    L +   +  +A  + G 
Sbjct  904   TGVGNTGDYNTGWFNSGDYNTGVLNSGNVNTGVLIAGNYNNGFLWRDDYQGLIA-IEAGI  962

Query  844   DRPRHRRRHSRNPDCERRREYP-DSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYRP  902
               P        N D       P D    +  + G  I   ++S  +S +     +    P
Sbjct  963   YIPEFPL---LNLDMGLPVNIPLDLGMSNLNIQGFTIPEFKASVLNSDYL----SVDIGP  1015

Query  903   LHRPSDT  909
             +  P+ T
Sbjct  1016  IVIPTIT  1022


 Score =  300 bits (767),  Expect = 1e-78, Method: Compositional matrix adjust.
 Identities = 187/349 (54%), Positives = 226/349 (65%), Gaps = 35/349 (10%)

Query  199   NLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSN  258
             N+G  N G  N+G+GN G  NVG GN GS+N G  NLG++N GL NLG  N+GF N G+ 
Sbjct  711   NVGFGNFGDGNIGSGNWGSGNVGPGNWGSHNTGLGNLGANNAGLGNLGDFNVGFGNAGNA  770

Query  259   NVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSG  318
             N+G GNTGSNN+GIGLTGNGQ+GFG+ NSGS N GLFNSGS NVGLFNSGTGN GIGNSG
Sbjct  771   NIGLGNTGSNNIGIGLTGNGQVGFGALNSGSGNSGLFNSGSNNVGLFNSGTGNVGIGNSG  830

Query  319   TGNFGLG------------------------------NTGSTNTGWFNTGDVNTGGFNPG  348
             TGNFG+G                              NTGS NTG+FNTGDVN+G  NPG
Sbjct  831   TGNFGIGNAGTANTGIGNPGIGNWGYGNPGNYNTGIANTGSVNTGFFNTGDVNSGTANPG  890

Query  349   SYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRG  408
              YN+G++NTGN NTG  N G+YNTG+FN+GDYNTGV N+GNVNTG  IAGNY+NG LWR 
Sbjct  891   DYNSGSYNTGNTNTGVGNTGDYNTGWFNSGDYNTGVLNSGNVNTGVLIAGNYNNGFLWRD  950

Query  409   DYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLP-FTSIVP----FV  463
             DYQGLI  +  + IP  P+      +P++  + +  S + I G  +P F + V       
Sbjct  951   DYQGLIAIEAGIYIPEFPLLNLDMGLPVNIPLDLGMSNLNIQGFTIPEFKASVLNSDYLS  1010

Query  464   VYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPA  512
             V  GP+ +P  T  LP +T  VG PTTT+   LT  VG + I  I IPA
Sbjct  1011  VDIGPIVIPTITGVLPQLTAQVGSPTTTVGAILTSGVGPIDIKFIDIPA  1059


 Score =  280 bits (717),  Expect = 8e-73, Method: Compositional matrix adjust.
 Identities = 215/453 (48%), Positives = 262/453 (58%), Gaps = 49/453 (10%)

Query  420  LEIPAIPINAQ---LFSMPIHQVM----VMPGSVMTIPGMRLPFTS-IVPFVVYYGPVE-  470
            + +P IP+N        +PI  V     V  G  MTI  +   FT+ I P     G +  
Sbjct  5    IHVPQIPVNVNGTLFIDIPITTVFDGNTVYSG--MTISDIPFGFTNHIGPIPALVGTINA  62

Query  471  --LPQSTLTLPTVTI--TVGGPTTT-IDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSS  525
              +PQ TL  PT     T+G P+T  I G   G +G   I +     APG+GNST+ PSS
Sbjct  63   LYIPQVTLASPTPAPHGTIGSPSTLPIIG--YGTIGPFDITIFNFGMAPGYGNSTSLPSS  120

Query  526  GFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTS  585
            GFFN+G G++SGF N G   SG+ N++    G SG  N G+  SG+AN+GNT+SG  NT 
Sbjct  121  GFFNSGIGSSSGFFNVGANNSGWQNVSFGGLGNSGIKNWGSALSGLANLGNTMSGWLNTG  180

Query  586  TSNLATPAFNSGLLHHSV-----------GTMTLNFGLANVGGNNVGGANAGIFN-----  629
            T +L+TPA  SG  +  V                N GL NVG  NVG  N G +N     
Sbjct  181  TVDLSTPANVSGFQNVGVNLAGFFRDYVTDATDFNLGLGNVGNWNVGFGNIGDYNLGSGN  240

Query  630  -----VGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLG----------FAN  674
                 VG  N+G YN+G GN+G  N+G A+ GSYN+G  N G+NN G          F N
Sbjct  241  NGSLNVGSGNIGLYNLGPGNVGNYNVGSANLGSYNVGLGNFGANNFGLGNFGDFNTGFGN  300

Query  675  TGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGI  734
             GD NIG  N G+ NIGIGLTG+GQ+GFG+LNSGS N GLFNSG  NIGLFNSG+GN GI
Sbjct  301  AGDANIGIGNSGTGNIGIGLTGTGQVGFGALNSGSGNSGLFNSGTNNIGLFNSGTGNVGI  360

Query  735  GNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGG  794
             N+GTGNWGIGNSG  N G+ NAG  NTGL N+G++NTG  N G YN+GS N GS NT G
Sbjct  361  ANSGTGNWGIGNSGHINTGLLNAGDINTGLINAGNVNTGIFNAGGYNSGSFNAGSFNTLG  420

Query  795  FNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHL  827
            FNAGNYNTGY NTGD               F+L
Sbjct  421  FNAGNYNTGYLNTGDYNTGLANSGDVDTGAFNL  453


 Score = 64.7 bits (156),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 100/303 (34%), Positives = 136/303 (45%), Gaps = 53/303 (17%)

Query  107  PAIVAANRAVLVSLVSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALM  166
            PA+V    A+ +  V+           + T A +  + +     ++GY    +     + 
Sbjct  54   PALVGTINALYIPQVT---------LASPTPAPHGTIGSPSTLPIIGY---GTIGPFDIT  101

Query  167  PFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLG  226
             F   +    G S  L S+    +G  S++GF     NVGANN G       NV FG LG
Sbjct  102  IFNFGMAPGYGNSTSLPSSGFFNSGIGSSSGF----FNVGANNSG-----WQNVSFGGLG  152

Query  227  SYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGF--GNTGSNNVGIGLTG---NGQIG  281
              N G  N GS   GLANLG    G+ NTG+ ++      +G  NVG+ L G   +    
Sbjct  153  --NSGIKNWGSALSGLANLGNTMSGWLNTGTVDLSTPANVSGFQNVGVNLAGFFRDYVTD  210

Query  282  FGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVN  341
               FN G  N+G +N G GN+G +N G+GN G  N G+GN GL                 
Sbjct  211  ATDFNLGLGNVGNWNVGFGNIGDYNLGSGNNGSLNVGSGNIGL-----------------  253

Query  342  TGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYS  401
                    YN G  N GNYN GS N G+YN G  N G  N G+ N G+ NTG   AG+ +
Sbjct  254  --------YNLGPGNVGNYNVGSANLGSYNVGLGNFGANNFGLGNFGDFNTGFGNAGDAN  305

Query  402  NGV  404
             G+
Sbjct  306  IGI  308


 Score = 46.2 bits (108),  Expect = 0.029, Method: Compositional matrix adjust.
 Identities = 56/147 (39%), Positives = 65/147 (45%), Gaps = 24/147 (16%)

Query  287  SGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDV------  340
            SG  N+G  NSG  NV     G GN GI N G+   GL N G+T +GW NTG V      
Sbjct  131  SGFFNVGANNSGWQNVSF--GGLGNSGIKNWGSALSGLANLGNTMSGWLNTGTVDLSTPA  188

Query  341  NTGGF----------------NPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGV  384
            N  GF                +   +N G  N GN+N G  N G+YN G  N G  N G 
Sbjct  189  NVSGFQNVGVNLAGFFRDYVTDATDFNLGLGNVGNWNVGFGNIGDYNLGSGNNGSLNVGS  248

Query  385  ANTGNVNTGAFIAGNYSNGVLWRGDYQ  411
             N G  N G    GNY+ G    G Y 
Sbjct  249  GNIGLYNLGPGNVGNYNVGSANLGSYN  275


>gi|308379758|ref|ZP_07669042.1| putative PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308363761|gb|EFP52612.1| putative PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=2358

 Score =  550 bits (1417),  Expect = 5e-154, Method: Compositional matrix adjust.
 Identities = 366/702 (53%), Positives = 460/702 (66%), Gaps = 60/702 (8%)

Query  198   FNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGS  257
             FN+G  N+G  NVG+G++G +N+G GNLG YN+GF N+G  N+G  N G  N GFANTG+
Sbjct  587   FNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNVGDYNVGFGNAGDFNQGFANTGN  646

Query  258   NNVGFGNTGSNNVGIGLTGNGQIGF-------------GSFNSGSHNIGLFNSGSGNVGL  304
             NN+GF NTG+NN+GIGL+G+ Q GF             G FNSG++N+G+FN+G+GNVG+
Sbjct  647   NNIGFANTGNNNIGIGLSGDNQQGFNIASGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGI  706

Query  305   FNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGS  364
              NSGTGN+GIGN GT N G+ N GS NTG  N GD NTG +N GSYNTG FN GN NTG+
Sbjct  707   ANSGTGNWGIGNPGTDNTGILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGN  766

Query  365   FNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPA  424
             FN G+ NTG +N GD NTG  N GNVNTGAF  G+++NG L  GD QG I  D+++  P 
Sbjct  767   FNVGDTNTGSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAIDLSVTTPF  826

Query  425   IPINAQLFSMPIHQVMVMPGSVMTI--PGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVT  482
             IPIN Q+  + +H VM   G+++T+       P T  +  + ++GPV L  STLT+PT+T
Sbjct  827   IPINEQMV-IDVHNVMTFGGNMITVTEASTVFPQTFYLSGLFFFGPVNLSASTLTVPTIT  885

Query  483   ITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFG  542
             +T+GGPT T+  ++ G +   +I  +KI  APG GNSTT+PSSGFFN+G G  SGF N G
Sbjct  886   LTIGGPTVTVPISIVGALESRTITFLKIDPAPGIGNSTTNPSSGFFNSGTGGTSGFQNVG  945

Query  543   GGASGFWN--LASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLH  600
             GG+SG WN  L+SA  G SGF N+G+L SG AN+GN++SG +NTST NL+TPA  SGL  
Sbjct  946   GGSSGVWNSGLSSAI-GNSGFQNLGSLQSGWANLGNSVSGFFNTSTVNLSTPANVSGL--  1002

Query  601   HSVGT-----------MTLNFGLANVGGNNVGGANAGIFNVGLANL----------GDYN  639
             +++GT              N GLAN+G  N+G AN G FN+G  N+          G YN
Sbjct  1003  NNIGTNLSGVFRGPTGTIFNAGLANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYN  1062

Query  640   IGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQ  699
             IG  NLG  N+GFA+ G+YNIGF N G  N GFANTG+NNIGFAN G+NNIGIGL+G  Q
Sbjct  1063  IGPANLGNYNIGFANLGNYNIGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQ  1122

Query  700   IGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGS  759
              GF       +  G +NSG  NIGLFNSG+ N GIGN+GTGNWGIGNSG+GN GIGN GS
Sbjct  1123  QGF-------NFAGGWNSGTANIGLFNSGTNNVGIGNSGTGNWGIGNSGSGNTGIGNTGS  1175

Query  760   TNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQ  819
             TNTG FN+G +NTG  N GSYNTG  NTG  NTG  N G++NTG++NTG+          
Sbjct  1176  TNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNTGIANLGDFNTGFYNTGNFSTGFANQGD  1235

Query  820   YQHRRF---------HLRQPQQRPSVAGRQPGSDRPRHRRRH  852
                  F           R  QQ    AG +P  + P H    
Sbjct  1236  IATGAFITGDMGNGAFWRGDQQGLFSAGYRP--EIPAHVTVE  1275



Lambda     K      H
   0.316    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 2386505962344




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40