BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0316 Length=204 Score E Sequences producing significant alignments: (Bits) Value gi|15607457|ref|NP_214830.1| muconolactone isomerase [Mycobacter... 397 6e-109 gi|308395141|ref|ZP_07491910.2| muconolactone isomerase [Mycobac... 397 7e-109 gi|306806122|ref|ZP_07442790.1| muconolactone isomerase [Mycobac... 395 2e-108 gi|340625347|ref|YP_004743799.1| putative muconolactone isomeras... 394 5e-108 gi|289756381|ref|ZP_06515759.1| muconolactone isomerase [Mycobac... 375 3e-102 gi|240173243|ref|ZP_04751901.1| putative muconolactone isomerase... 286 1e-75 gi|183980596|ref|YP_001848887.1| muconolactone isomerase [Mycoba... 270 8e-71 gi|118466629|ref|YP_881264.1| muconolactone delta-isomerase [Myc... 220 7e-56 gi|254774771|ref|ZP_05216287.1| muconolactone delta-isomerase fa... 220 1e-55 gi|41408226|ref|NP_961062.1| hypothetical protein MAP2128c [Myco... 217 1e-54 gi|256394920|ref|YP_003116484.1| Muconolactone delta-isomerase [... 197 9e-49 gi|254380455|ref|ZP_04995821.1| conserved hypothetical protein [... 142 3e-32 gi|118617747|ref|YP_906079.1| muconolactone isomerase [Mycobacte... 140 1e-31 gi|339328041|ref|YP_004687733.1| methylmuconolactone isomerase M... 69.7 2e-10 gi|257057777|ref|YP_003135609.1| muconolactone delta-isomerase [... 69.7 2e-10 gi|121605019|ref|YP_982348.1| muconolactone delta-isomerase [Pol... 68.6 5e-10 gi|326330249|ref|ZP_08196560.1| putative muconolactone delta-iso... 67.4 1e-09 gi|54025493|ref|YP_119735.1| putative muconolactone delta-isomer... 67.0 2e-09 gi|326774678|ref|ZP_08233943.1| Muconolactone delta-isomerase [S... 67.0 2e-09 gi|19553599|ref|NP_601601.1| hypothetical protein NCgl2317 [Cory... 66.6 2e-09 gi|222109380|ref|YP_002551644.1| muconolactone delta-isomerase [... 66.6 2e-09 gi|29828066|ref|NP_822700.1| muconolactone delta-isomerase [Stre... 66.2 3e-09 gi|330826203|ref|YP_004389506.1| muconolactone delta-isomerase [... 66.2 3e-09 gi|157837426|gb|ABV82779.1| muconolactone delta-isomerase [Chrom... 66.2 3e-09 gi|94313799|ref|YP_587008.1| Muconolactone delta-isomerase [Cupr... 66.2 3e-09 gi|284043826|ref|YP_003394166.1| Muconolactone delta-isomerase [... 66.2 3e-09 gi|73541193|ref|YP_295713.1| muconolactone delta-isomerase [Rals... 65.9 3e-09 gi|149375486|ref|ZP_01893256.1| Muconolactone delta-isomerase [M... 65.5 4e-09 gi|325964841|ref|YP_004242747.1| muconolactone delta-isomerase [... 65.5 4e-09 gi|6014743|sp|O33947.1|CATC1_ACILW RecName: Full=Muconolactone D... 65.5 4e-09 gi|121592576|ref|YP_984472.1| muconolactone delta-isomerase [Aci... 65.5 4e-09 gi|262368304|ref|ZP_06061633.1| muconolactone delta-isomerase [A... 65.5 4e-09 gi|296533379|ref|ZP_06895978.1| methylmuconolactone isomerase [R... 65.1 6e-09 gi|182434156|ref|YP_001821875.1| putative methylmuconolactone is... 64.3 1e-08 gi|345299626|ref|YP_004828984.1| muconolactone delta-isomerase [... 63.9 1e-08 gi|254389169|ref|ZP_05004398.1| conserved hypothetical protein [... 63.9 1e-08 gi|241663026|ref|YP_002981386.1| muconolactone delta-isomerase [... 63.9 1e-08 gi|187928449|ref|YP_001898936.1| muconolactone delta-isomerase [... 63.5 2e-08 gi|325527352|gb|EGD04711.1| muconolactone delta-isomerase [Burkh... 63.5 2e-08 gi|300691535|ref|YP_003752530.1| muconolactone delta-isomerase (... 62.8 3e-08 gi|160897312|ref|YP_001562894.1| muconolactone delta-isomerase [... 62.4 3e-08 gi|238024139|ref|YP_002908371.1| Muconolactone Delta-isomerase [... 62.4 3e-08 gi|158423963|ref|YP_001525255.1| methylmuconolactone isomerase [... 62.4 4e-08 gi|344166822|emb|CCA79010.1| muconolactone delta-isomerase (MIas... 62.4 4e-08 gi|23491544|dbj|BAC16776.1| muconolactone isomerase [Burkholderi... 62.0 5e-08 gi|334195978|gb|AEG69163.1| muconolactone delta-isomerase [Ralst... 61.6 6e-08 gi|187476821|ref|YP_784845.1| methylmuconolactone isomerase [Bor... 61.6 6e-08 gi|38638065|ref|NP_943039.1| putative muconolactone isomerase [R... 61.6 6e-08 gi|307725880|ref|YP_003909093.1| muconolactone delta-isomerase [... 61.6 7e-08 gi|118471569|ref|YP_886278.1| muconolactone delta-isomerase 1 [M... 61.6 7e-08 >gi|15607457|ref|NP_214830.1| muconolactone isomerase [Mycobacterium tuberculosis H37Rv] gi|15839703|ref|NP_334740.1| muconolactone isomerase, putative [Mycobacterium tuberculosis CDC1551] gi|31791495|ref|NP_853988.1| muconolactone isomerase [Mycobacterium bovis AF2122/97] 69 more sequence titles Length=204 Score = 397 bits (1019), Expect = 6e-109, Method: Compositional matrix adjust. Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA Sbjct 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG Sbjct 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL Sbjct 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 Query 181 PLAGWMTIETTPLSPHPDDPIRMP 204 PLAGWMTIETTPLSPHPDDPIRMP Sbjct 181 PLAGWMTIETTPLSPHPDDPIRMP 204 >gi|308395141|ref|ZP_07491910.2| muconolactone isomerase [Mycobacterium tuberculosis SUMu012] gi|308367463|gb|EFP56314.1| muconolactone isomerase [Mycobacterium tuberculosis SUMu012] gi|323721265|gb|EGB30322.1| muconolactone isomerase [Mycobacterium tuberculosis CDC1551A] Length=213 Score = 397 bits (1019), Expect = 7e-109, Method: Compositional matrix adjust. Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA Sbjct 10 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 69 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG Sbjct 70 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 129 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL Sbjct 130 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 189 Query 181 PLAGWMTIETTPLSPHPDDPIRMP 204 PLAGWMTIETTPLSPHPDDPIRMP Sbjct 190 PLAGWMTIETTPLSPHPDDPIRMP 213 Score = 81.3 bits (199), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 47/98 (48%), Positives = 59/98 (61%), Gaps = 0/98 (0%) Query 104 GKGPEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLG 163 G+ EFL+ T VP PA V+ AREA R+ ELA +G L+RLW P P RTLG Sbjct 7 GESMEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLG 66 Query 164 LWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDPI 201 L+ A D GEL +L S+P W T + TPL HP+DP+ Sbjct 67 LFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPV 104 >gi|306806122|ref|ZP_07442790.1| muconolactone isomerase [Mycobacterium tuberculosis SUMu007] gi|306966320|ref|ZP_07478981.1| muconolactone isomerase [Mycobacterium tuberculosis SUMu009] gi|308347378|gb|EFP36229.1| muconolactone isomerase [Mycobacterium tuberculosis SUMu007] gi|308355953|gb|EFP44804.1| muconolactone isomerase [Mycobacterium tuberculosis SUMu009] Length=204 Score = 395 bits (1016), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 203/204 (99%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA Sbjct 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 ADDNG+LEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG Sbjct 61 ADDNGDLEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL Sbjct 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 Query 181 PLAGWMTIETTPLSPHPDDPIRMP 204 PLAGWMTIETTPLSPHPDDPIRMP Sbjct 181 PLAGWMTIETTPLSPHPDDPIRMP 204 >gi|340625347|ref|YP_004743799.1| putative muconolactone isomerase [Mycobacterium canettii CIPT 140010059] gi|340003537|emb|CCC42658.1| putative muconolactone isomerase [Mycobacterium canettii CIPT 140010059] Length=204 Score = 394 bits (1011), Expect = 5e-108, Method: Compositional matrix adjust. Identities = 203/204 (99%), Positives = 203/204 (99%), Gaps = 0/204 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA Sbjct 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVP G Sbjct 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPLG 120 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL Sbjct 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 Query 181 PLAGWMTIETTPLSPHPDDPIRMP 204 PLAGWMTIETTPLSPHPDDPIRMP Sbjct 181 PLAGWMTIETTPLSPHPDDPIRMP 204 >gi|289756381|ref|ZP_06515759.1| muconolactone isomerase [Mycobacterium tuberculosis T85] gi|289711945|gb|EFD75957.1| muconolactone isomerase [Mycobacterium tuberculosis T85] Length=207 Score = 375 bits (962), Expect = 3e-102, Method: Compositional matrix adjust. Identities = 193/193 (100%), Positives = 193/193 (100%), Gaps = 0/193 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA Sbjct 10 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 69 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG Sbjct 70 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 129 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL Sbjct 130 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 189 Query 181 PLAGWMTIETTPL 193 PLAGWMTIETTPL Sbjct 190 PLAGWMTIETTPL 202 Score = 82.0 bits (201), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 47/98 (48%), Positives = 59/98 (61%), Gaps = 0/98 (0%) Query 104 GKGPEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLG 163 G+ EFL+ T VP PA V+ AREA R+ ELA +G L+RLW P P RTLG Sbjct 7 GESMEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLG 66 Query 164 LWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDPI 201 L+ A D GEL +L S+P W T + TPL HP+DP+ Sbjct 67 LFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPV 104 >gi|240173243|ref|ZP_04751901.1| putative muconolactone isomerase [Mycobacterium kansasii ATCC 12478] Length=204 Score = 286 bits (732), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 156/202 (78%), Positives = 168/202 (84%), Gaps = 0/202 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLVTMTTRVPD D V VRAREAA +RELAA+G LLRLWRPP+RPGEWRTLGLFA Sbjct 1 MEFLVTMTTRVPDGTSLDEVNDVRAREAAHARELAARGSLLRLWRPPVRPGEWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 A D+ LEQLLASMP R WRTD++T L HP+DP G GIT PGKGPEFLIA T+ VPPG Sbjct 61 AADDERLEQLLASMPLRVWRTDEITALDGHPDDPPGAGITPRPGKGPEFLIAMTVTVPPG 120 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 T A VVDD AR+ARRA ELA GHLVRLW LPDGPDG +GLWRARDPGELMAILESL Sbjct 121 TAAHVVDDASARQARRARELAEAGHLVRLWTLPDGPDGPCMVGLWRARDPGELMAILESL 180 Query 181 PLAGWMTIETTPLSPHPDDPIR 202 PL+GWMTIETTPLSPHP+DPIR Sbjct 181 PLSGWMTIETTPLSPHPNDPIR 202 >gi|183980596|ref|YP_001848887.1| muconolactone isomerase [Mycobacterium marinum M] gi|183173922|gb|ACC39032.1| muconolactone isomerase [Mycobacterium marinum M] Length=219 Score = 270 bits (690), Expect = 8e-71, Method: Compositional matrix adjust. Identities = 137/203 (68%), Positives = 156/203 (77%), Gaps = 0/203 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV+MT VP PA ++R R E A REL AQG+LLRLWRPP PG+W TLGLFA Sbjct 1 MEFLVSMTIEVPRGTPAAEIDRARVSENAGWRELGAQGRLLRLWRPPCGPGQWCTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 A D L +LL ++P + WR+D+V LGAHPNDP+G G+T PGKGPEFLI TT+ VP G Sbjct 61 ARDEPSLRKLLVTVPVQDWRSDEVAVLGAHPNDPLGAGVTPRPGKGPEFLITTTLTVPSG 120 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 T A+VVDD REARR ELA GHLVR WALP GPDG R LGLWRARDPGELMA++ESL Sbjct 121 TSARVVDDATEREARRCHELAEAGHLVRFWALPAGPDGPRMLGLWRARDPGELMAVVESL 180 Query 181 PLAGWMTIETTPLSPHPDDPIRM 203 PL+GWMTIETTPL PHP DPIR+ Sbjct 181 PLSGWMTIETTPLRPHPSDPIRL 203 >gi|118466629|ref|YP_881264.1| muconolactone delta-isomerase [Mycobacterium avium 104] gi|118167916|gb|ABK68813.1| muconolactone delta-isomerase family protein [Mycobacterium avium 104] Length=211 Score = 220 bits (561), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 122/204 (60%), Positives = 141/204 (70%), Gaps = 3/204 (1%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV TT+VPD PA+AV+ +RARE+AR RELA QG+LLRLWR P PG WRTLGLFA Sbjct 1 MEFLVAATTQVPDGTPAEAVDDLRARESARCRELARQGQLLRLWRAPSPPGRWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAP--GKGPEFLIATTIMVP 118 A D+ LEQLLAS P R+WRT++VTPL HPNDP + IT P G EFL A TI VP Sbjct 61 AADDNALEQLLASTPLRAWRTEEVTPLPVHPNDPTARLITPEPVSGGAAEFLQAITIRVP 120 Query 119 PGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILE 178 P +VVDD +AREA RA EL +G L RLW L GP R L LWR D L A+L Sbjct 121 ADAPQRVVDDVLAREAERAVELGAQGCLQRLWWLHSGPGDPRVLALWRTADTESLAAVLR 180 Query 179 SLPLAGWMTIE-TTPLSPHPDDPI 201 SLPL W+ ++ TTPL HPDDP+ Sbjct 181 SLPLHAWLQVDTTTPLHTHPDDPV 204 >gi|254774771|ref|ZP_05216287.1| muconolactone delta-isomerase family protein [Mycobacterium avium subsp. avium ATCC 25291] Length=211 Score = 220 bits (560), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 122/204 (60%), Positives = 141/204 (70%), Gaps = 3/204 (1%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV TT+VPD PA+AV+ +RARE+AR RELA QG+LLRLWR P PG WRTLGLFA Sbjct 1 MEFLVAATTQVPDGTPAEAVDDLRARESARCRELARQGQLLRLWRAPSPPGRWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAP--GKGPEFLIATTIMVP 118 A D+ LEQLLAS P R+WRT++VTPL HPNDP + IT P G EFL A TI VP Sbjct 61 AADDNALEQLLASTPLRAWRTEEVTPLPVHPNDPTARLITPEPVSGGAAEFLQAITIRVP 120 Query 119 PGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILE 178 P +VVDD +AREA RA EL +G L RLW L GP R L LWR D L A+L Sbjct 121 ADAPQRVVDDVLAREAERAGELGAQGCLQRLWWLHSGPGEPRVLALWRTADTESLAAVLR 180 Query 179 SLPLAGWMTIE-TTPLSPHPDDPI 201 SLPL W+ ++ TTPL HPDDP+ Sbjct 181 SLPLHAWLQVDTTTPLHTHPDDPV 204 >gi|41408226|ref|NP_961062.1| hypothetical protein MAP2128c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396581|gb|AAS04445.1| hypothetical protein MAP_2128c [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461674|gb|EGO40537.1| muconolactone delta-isomerase [Mycobacterium avium subsp. paratuberculosis S397] Length=211 Score = 217 bits (552), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 121/204 (60%), Positives = 140/204 (69%), Gaps = 3/204 (1%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV TT+VPD PA+AV+ +RAR +AR RELA QG+LLRLWR P PG WRTLGLFA Sbjct 1 MEFLVAATTQVPDGTPAEAVDDLRARVSARCRELARQGQLLRLWRAPSPPGRWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKG--PEFLIATTIMVP 118 A D+ LEQLLAS P R+WRT++VTPL HPNDP + IT P G EFL A TI VP Sbjct 61 AADDNALEQLLASTPLRAWRTEEVTPLPVHPNDPTARLITPEPVSGGTAEFLQAITIRVP 120 Query 119 PGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILE 178 P +VVDD +AREA RA EL +G L RLW L GP R L LWR D L A+L Sbjct 121 ADAPQRVVDDVLAREAERAGELGAQGCLQRLWWLHSGPGEPRVLALWRTADTESLAAVLR 180 Query 179 SLPLAGWMTIE-TTPLSPHPDDPI 201 SLPL W+ ++ TTPL HPDDP+ Sbjct 181 SLPLHAWLQVDTTTPLHTHPDDPV 204 >gi|256394920|ref|YP_003116484.1| Muconolactone delta-isomerase [Catenulispora acidiphila DSM 44928] gi|256361146|gb|ACU74643.1| Muconolactone delta-isomerase [Catenulispora acidiphila DSM 44928] Length=200 Score = 197 bits (500), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 111/202 (55%), Positives = 137/202 (68%), Gaps = 6/202 (2%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 ME+LVTMTT VP+ A V+ +RARE +RELAAQG+++RLWRPPL PGEWRT+GLF Sbjct 1 MEYLVTMTTHVPEGTSAQEVDAMRAREGEHTRELAAQGRVVRLWRPPLAPGEWRTIGLFT 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPG 120 A+D G+LE+ LASMP R WRTD+ LG H NDP G+G E+L+ + VP G Sbjct 61 AEDAGDLERTLASMPLRMWRTDEPVALGVHGNDP-GRGAVAPVAGDAEYLVTFHVRVPEG 119 Query 121 TPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESL 180 A+ V+ A EARRA ELA G LVRLW+L P+ LGLW+A D + A L SL Sbjct 120 ADAEAVEQMNAGEARRAAELAEEGRLVRLWSL---PEQGHNLGLWQAPDAAAVDADLRSL 176 Query 181 PL--AGWMTIETTPLSPHPDDP 200 P+ AGW+T+ET PLSPHP DP Sbjct 177 PMTAAGWLTVETLPLSPHPSDP 198 Score = 74.7 bits (182), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 44/95 (47%), Positives = 53/95 (56%), Gaps = 0/95 (0%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRA 167 E+L+ T VP GT AQ VD ARE ELA +G +VRLW P P RT+GL+ A Sbjct 2 EYLVTMTTHVPEGTSAQEVDAMRAREGEHTRELAAQGRVVRLWRPPLAPGEWRTIGLFTA 61 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHPDDPIR 202 D G+L L S+PL W T E L H +DP R Sbjct 62 EDAGDLERTLASMPLRMWRTDEPVALGVHGNDPGR 96 Score = 62.4 bits (150), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 41/97 (43%), Positives = 57/97 (59%), Gaps = 5/97 (5%) Query 2 EFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAA 61 E+LVT RVP+ A+AVE++ A EA R+ ELA +G+L+RLW P + LGL+ A Sbjct 107 EYLVTFHVRVPEGADAEAVEQMNAGEARRAAELAEEGRLVRLWS---LPEQGHNLGLWQA 163 Query 62 DDNGELEQLLASMP--PRSWRTDDVTPLGAHPNDPVG 96 D ++ L S+P W T + PL HP+DP G Sbjct 164 PDAAAVDADLRSLPMTAAGWLTVETLPLSPHPSDPAG 200 >gi|254380455|ref|ZP_04995821.1| conserved hypothetical protein [Streptomyces sp. Mg1] gi|194339366|gb|EDX20332.1| conserved hypothetical protein [Streptomyces sp. Mg1] Length=101 Score = 142 bits (358), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 72/100 (72%), Positives = 78/100 (78%), Gaps = 0/100 (0%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 ME+LVTMTT VPD AVE +R REA RSRELAAQG LLRLWRPPL+PGEWRTLGLFA Sbjct 1 MEYLVTMTTHVPDGTSEQAVEDIRTREATRSRELAAQGHLLRLWRPPLQPGEWRTLGLFA 60 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGIT 100 A D LE++LASMP R WRTD+VTPL HPNDP G T Sbjct 61 AADADRLEEVLASMPLRIWRTDEVTPLSPHPNDPAGTAGT 100 Score = 90.1 bits (222), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 49/93 (53%), Positives = 59/93 (64%), Gaps = 0/93 (0%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRA 167 E+L+ T VP GT Q V+D REA R+ ELA +GHL+RLW P P RTLGL+ A Sbjct 2 EYLVTMTTHVPDGTSEQAVEDIRTREATRSRELAAQGHLLRLWRPPLQPGEWRTLGLFAA 61 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHPDDP 200 D L +L S+PL W T E TPLSPHP+DP Sbjct 62 ADADRLEEVLASMPLRIWRTDEVTPLSPHPNDP 94 >gi|118617747|ref|YP_906079.1| muconolactone isomerase [Mycobacterium ulcerans Agy99] gi|118569857|gb|ABL04608.1| muconolactone isomerase [Mycobacterium ulcerans Agy99] Length=110 Score = 140 bits (352), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 69/94 (74%), Positives = 76/94 (81%), Gaps = 0/94 (0%) Query 110 LIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARD 169 +I TT+ VP GT +VVDD REARR ELA GHLVR WALP GPDG R LGLWRARD Sbjct 1 MITTTLTVPSGTSVRVVDDATEREARRCHELAEAGHLVRFWALPAGPDGPRMLGLWRARD 60 Query 170 PGELMAILESLPLAGWMTIETTPLSPHPDDPIRM 203 PGELMA++ESLPL+GWMTIETTPL PHP DPIR+ Sbjct 61 PGELMAVVESLPLSGWMTIETTPLRPHPSDPIRL 94 Score = 65.1 bits (157), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 38/92 (42%), Positives = 49/92 (54%), Gaps = 0/92 (0%) Query 4 LVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAADD 63 ++T T VP V+ REA R ELA G L+R W P P R LGL+ A D Sbjct 1 MITTTLTVPSGTSVRVVDDATEREARRCHELAEAGHLVRFWALPAGPDGPRMLGLWRARD 60 Query 64 NGELEQLLASMPPRSWRTDDVTPLGAHPNDPV 95 GEL ++ S+P W T + TPL HP+DP+ Sbjct 61 PGELMAVVESLPLSGWMTIETTPLRPHPSDPI 92 >gi|339328041|ref|YP_004687733.1| methylmuconolactone isomerase MmlJ [Cupriavidus necator N-1] gi|338170642|gb|AEI81695.1| methylmuconolactone isomerase MmlJ [Cupriavidus necator N-1] Length=91 Score = 69.7 bits (169), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 35/92 (39%), Positives = 54/92 (59%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M + V M ++P+S+PAD V+ ++A E AR+ E+ GK LWR G + + +F Sbjct 1 MLYCVQMDVKIPESLPADRVDTLKAAEKARAIEIQKAGKWPHLWRV---VGRYSNVSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N EL +LL+S+P + T VTPL HP+ Sbjct 58 VESNDELHELLSSLPLFPYMTIQVTPLAKHPS 89 Score = 46.2 bits (108), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/89 (32%), Positives = 41/89 (47%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 + + + +P PA VD A E RA E+ G LW + + ++ Sbjct 3 YCVQMDVKIPESLPADRVDTLKAAEKARAIEIQKAGKWPHLWRVVGR---YSNVSVFDVE 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L SLPL +MTI+ TPL+ HP Sbjct 60 SNDELHELLSSLPLFPYMTIQVTPLAKHP 88 >gi|257057777|ref|YP_003135609.1| muconolactone delta-isomerase [Saccharomonospora viridis DSM 43017] gi|256587649|gb|ACU98782.1| muconolactone delta-isomerase [Saccharomonospora viridis DSM 43017] Length=94 Score = 69.7 bits (169), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 42/93 (46%), Positives = 52/93 (56%), Gaps = 3/93 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV R+P + P + ER+RA E R+ EL AQG L RLWR PG T+GL+ Sbjct 1 MEFLVRSENRLPPTTPPEERERLRAAERERAMELRAQGVLKRLWRV---PGRNATIGLYE 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPND 93 ADD +L L S+P W V PL HP + Sbjct 58 ADDATQLHDALMSLPMAPWLDITVEPLATHPQE 90 Score = 58.5 bits (140), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 37/92 (41%), Positives = 52/92 (57%), Gaps = 3/92 (3%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRA 167 EFL+ + +PP TP + + A E RA EL +G L RLW +P G + T+GL+ A Sbjct 2 EFLVRSENRLPPTTPPEERERLRAAERERAMELRAQGVLKRLWRVP-GRNA--TIGLYEA 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHPDD 199 D +L L SLP+A W+ I PL+ HP + Sbjct 59 DDATQLHDALMSLPMAPWLDITVEPLATHPQE 90 >gi|121605019|ref|YP_982348.1| muconolactone delta-isomerase [Polaromonas naphthalenivorans CJ2] gi|120593988|gb|ABM37427.1| muconolactone delta-isomerase [Polaromonas naphthalenivorans CJ2] Length=92 Score = 68.6 bits (166), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 36/92 (40%), Positives = 49/92 (54%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M FLV M +P +PAD ++ARE A S++L G+ +WR GE+ +F Sbjct 1 MLFLVRMDVNIPRDLPADEANEIKAREKAYSQDLQRDGRWKSIWRV---VGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 N EL QLL +P + DVTPL AHP+ Sbjct 58 VSSNDELHQLLQGLPLFPFMKIDVTPLAAHPS 89 Score = 40.4 bits (93), Expect = 0.16, Method: Compositional matrix adjust. Identities = 25/90 (28%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 FL+ + +P PA ++ ARE + +L G +W + G+ ++ Sbjct 3 FLVRMDVNIPRDLPADEANEIKAREKAYSQDLQRDGRWKSIWRVV----GEYANYSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L+ LPL +M I+ TPL+ HP Sbjct 59 SSNDELHQLLQGLPLFPFMKIDVTPLAAHP 88 >gi|326330249|ref|ZP_08196560.1| putative muconolactone delta-isomerase [Nocardioidaceae bacterium Broad-1] gi|325952062|gb|EGD44091.1| putative muconolactone delta-isomerase [Nocardioidaceae bacterium Broad-1] Length=98 Score = 67.4 bits (163), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 46/95 (49%), Positives = 60/95 (64%), Gaps = 6/95 (6%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQ-RTLGLWR 166 EF++ T ++P GTP VD EA RA ELA GHLVR+W P G+ R++GLW Sbjct 3 EFIVEITTVIPEGTPQTEVDRRRTAEAARAAELAAAGHLVRIW----RPIGEMRSIGLWV 58 Query 167 ARDPGELMA-ILESLPLAGWMTIETTPLSPHPDDP 200 A D L A +LE+LPLA WMT + T ++ HP+DP Sbjct 59 AADEAALRADVLETLPLAPWMTFDVTAVASHPNDP 93 Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 44/97 (46%), Positives = 61/97 (63%), Gaps = 4/97 (4%) Query 2 EFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAA 61 EF+V +TT +P+ P V+R R EAAR+ ELAA G L+R+WRP GE R++GL+ A Sbjct 3 EFIVEITTVIPEGTPQTEVDRRRTAEAARAAELAAAGHLVRIWRP---IGEMRSIGLWVA 59 Query 62 DDNGELE-QLLASMPPRSWRTDDVTPLGAHPNDPVGQ 97 D L +L ++P W T DVT + +HPNDP + Sbjct 60 ADEAALRADVLETLPLAPWMTFDVTAVASHPNDPAAR 96 >gi|54025493|ref|YP_119735.1| putative muconolactone delta-isomerase [Nocardia farcinica IFM 10152] gi|54017001|dbj|BAD58371.1| putative muconolactone delta-isomerase [Nocardia farcinica IFM 10152] Length=94 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 37/96 (39%), Positives = 50/96 (53%), Gaps = 3/96 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P +PAD + ARE A S+EL GK +LWR GE+ +F Sbjct 1 MLFHVRMDVRIPHDLPADTRAEIVAREKAYSQELQRAGKWPQLWRI---VGEYSNFSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVG 96 + N EL +LL+ +P + VTPL HP+ G Sbjct 58 VESNDELHELLSGLPLFPYMDIHVTPLATHPSKVAG 93 Score = 40.4 bits (93), Expect = 0.15, Method: Compositional matrix adjust. Identities = 26/89 (30%), Positives = 38/89 (43%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 F + + +P PA + VARE + EL G +LW + ++ Sbjct 3 FHVRMDVRIPHDLPADTRAEIVAREKAYSQELQRAGKWPQLWRIVGE---YSNFSIFDVE 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L LPL +M I TPL+ HP Sbjct 60 SNDELHELLSGLPLFPYMDIHVTPLATHP 88 >gi|326774678|ref|ZP_08233943.1| Muconolactone delta-isomerase [Streptomyces cf. griseus XylebKG-1] gi|326655011|gb|EGE39857.1| Muconolactone delta-isomerase [Streptomyces griseus XylebKG-1] Length=95 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 43/97 (45%), Positives = 53/97 (55%), Gaps = 11/97 (11%) Query 108 EFLIATTIMVP----PGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLG 163 EFL+ I P P A+V DD E RRA ELA G LVR+W +P + G Sbjct 2 EFLVNIHITWPEAMDPDLKAKVSDD----ERRRAAELAASGTLVRMWRVPGRTEN---WG 54 Query 164 LWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDP 200 LWRA DP EL A++ SLP+ WM + L+ HP DP Sbjct 55 LWRAADPTELHAVISSLPVWPWMEVTVHALADHPVDP 91 Score = 62.4 bits (150), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 39/98 (40%), Positives = 51/98 (53%), Gaps = 3/98 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV + P++M D +V E R+ ELAA G L+R+WR P R W GL+ Sbjct 1 MEFLVNIHITWPEAMDPDLKAKVSDDERRRAAELAASGTLVRMWRVPGRTENW---GLWR 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQG 98 A D EL +++S+P W V L HP DP G Sbjct 58 AADPTELHAVISSLPVWPWMEVTVHALADHPVDPAPAG 95 >gi|19553599|ref|NP_601601.1| hypothetical protein NCgl2317 [Corynebacterium glutamicum ATCC 13032] gi|62391243|ref|YP_226645.1| hypothetical protein cg2634 [Corynebacterium glutamicum ATCC 13032] gi|145296367|ref|YP_001139188.1| hypothetical protein cgR_2282 [Corynebacterium glutamicum R] gi|21325171|dbj|BAB99793.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032] gi|41326583|emb|CAF21065.1| MUCONOLACTONE ISOMERASE [Corynebacterium glutamicum ATCC 13032] gi|140846287|dbj|BAF55286.1| hypothetical protein [Corynebacterium glutamicum R] gi|344044595|gb|EGV40271.1| muconolactone delta-isomerase [Corynebacterium glutamicum S9114] Length=97 Score = 66.6 bits (161), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 48/92 (53%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M FL M PDSM AD + +A+E A S +L ++G + +WR GE+ +F Sbjct 1 MLFLARMDVVFPDSMDADVMADFQAKEKAYSGDLQSRGIMKAIWRVV---GEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 DD+ EL +L+ P + +TPL HPN Sbjct 58 VDDHDELHAILSGFPMFKYMNVKITPLAKHPN 89 Score = 47.8 bits (112), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/91 (29%), Positives = 44/91 (49%), Gaps = 5/91 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 FL ++ P A V+ D A+E + +L RG + +W + G+ ++ Sbjct 3 FLARMDVVFPDSMDADVMADFQAKEKAYSGDLQSRGIMKAIWRVV----GEYANYSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHPD 198 D EL AIL P+ +M ++ TPL+ HP+ Sbjct 59 DDHDELHAILSGFPMFKYMNVKITPLAKHPN 89 >gi|222109380|ref|YP_002551644.1| muconolactone delta-isomerase [Acidovorax ebreus TPSY] gi|221728824|gb|ACM31644.1| muconolactone delta-isomerase [Acidovorax ebreus TPSY] Length=98 Score = 66.6 bits (161), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 37/104 (36%), Positives = 54/104 (52%), Gaps = 6/104 (5%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M FLV M ++P +PA + ++ARE S++L G+ +WR GE+ +F Sbjct 1 MLFLVRMDVKIPHDLPAAQADEIKAREKKYSQDLQRDGRWRHIWRV---VGEYANYSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPG 104 N EL QLL+ +P + VTPL HP+ V +G APG Sbjct 58 VQSNDELHQLLSQLPLFPYMDIHVTPLANHPSAIVQEG---APG 98 Score = 43.9 bits (102), Expect = 0.013, Method: Compositional matrix adjust. Identities = 26/90 (29%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 FL+ + +P PA D+ ARE + + +L G +W + G+ ++ Sbjct 3 FLVRMDVKIPHDLPAAQADEIKAREKKYSQDLQRDGRWRHIWRVV----GEYANYSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 + EL +L LPL +M I TPL+ HP Sbjct 59 QSNDELHQLLSQLPLFPYMDIHVTPLANHP 88 >gi|29828066|ref|NP_822700.1| muconolactone delta-isomerase [Streptomyces avermitilis MA-4680] gi|29605168|dbj|BAC69235.1| putative muconolactone delta-isomerase [Streptomyces avermitilis MA-4680] Length=217 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 49/94 (53%), Positives = 63/94 (68%), Gaps = 4/94 (4%) Query 2 EFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAA 61 EFLV +TT +P+ V+R RA EA R+ ELAA G L RLWRP GE R++G++ A Sbjct 120 EFLVEITTTIPEGTEPAEVDRRRAAEAVRAEELAATGNLFRLWRP---VGELRSIGVWRA 176 Query 62 DDNGEL-EQLLASMPPRSWRTDDVTPLGAHPNDP 94 D EL E++L ++P RSW T VTPL +HPNDP Sbjct 177 ADEDELHEKVLGTLPLRSWMTLTVTPLESHPNDP 210 Score = 62.0 bits (149), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 47/97 (49%), Positives = 58/97 (60%), Gaps = 6/97 (6%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQ-RTLGLWR 166 EFL+ T +P GT VD A EA RA ELA G+L RLW P G+ R++G+WR Sbjct 120 EFLVEITTTIPEGTEPAEVDRRRAAEAVRAEELAATGNLFRLWR----PVGELRSIGVWR 175 Query 167 ARDPGELM-AILESLPLAGWMTIETTPLSPHPDDPIR 202 A D EL +L +LPL WMT+ TPL HP+DP R Sbjct 176 AADEDELHEKVLGTLPLRSWMTLTVTPLESHPNDPGR 212 >gi|330826203|ref|YP_004389506.1| muconolactone delta-isomerase [Alicycliphilus denitrificans K601] gi|329311575|gb|AEB85990.1| muconolactone delta-isomerase [Alicycliphilus denitrificans K601] Length=92 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 50/92 (55%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F M R+P + V+ ++ RE AR+ EL QGK L LWR G++ + +F Sbjct 1 MLFCARMEVRIPHDLDPAFVQSLKEREKARAIELQQQGKFLHLWRV---VGQYANISIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 N EL ++L+S+P + +VTPL HP+ Sbjct 58 CASNDELHEVLSSLPLFPYLQIEVTPLARHPS 89 Score = 43.9 bits (102), Expect = 0.013, Method: Compositional matrix adjust. Identities = 28/90 (32%), Positives = 40/90 (45%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + +P V RE RA EL +G + LW + GQ + ++ Sbjct 3 FCARMEVRIPHDLDPAFVQSLKEREKARAIELQQQGKFLHLWRVV----GQYANISIFDC 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L SLPL ++ IE TPL+ HP Sbjct 59 ASNDELHEVLSSLPLFPYLQIEVTPLARHP 88 >gi|157837426|gb|ABV82779.1| muconolactone delta-isomerase [Chromohalobacter sp. HS2] Length=96 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 31/92 (34%), Positives = 52/92 (57%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V MT ++P MP++ ++A+E A S+EL GK LWR G + + +F Sbjct 1 MLFQVQMTVKLPTDMPSNQAAEIKAKEKAYSQELQHAGKWRHLWRV---AGSYENVSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 +DN EL+++++ +P + +V PL HP+ Sbjct 58 VEDNAELQEIISGLPLFPYMEINVKPLCRHPS 89 Score = 42.7 bits (99), Expect = 0.031, Method: Compositional matrix adjust. Identities = 24/89 (27%), Positives = 38/89 (43%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 F + T+ +P P+ + A+E + EL G LW + + + ++ Sbjct 3 FQVQMTVKLPTDMPSNQAAEIKAKEKAYSQELQHAGKWRHLWRVAGSYEN---VSVFDVE 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 D EL I+ LPL +M I PL HP Sbjct 60 DNAELQEIISGLPLFPYMEINVKPLCRHP 88 >gi|94313799|ref|YP_587008.1| Muconolactone delta-isomerase [Cupriavidus metallidurans CH34] gi|93357651|gb|ABF11739.1| Muconolactone delta-isomerase [Cupriavidus metallidurans CH34] Length=92 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/92 (39%), Positives = 51/92 (56%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M FLV M ++P +PA + ++ARE A S++L QGK L+R GE+ LF Sbjct 1 MLFLVRMDVQIPHDLPAAEADEIKAREKAYSQDLQRQGKWQALYRV---VGEYANYSLFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N EL LL+++P + VTPL HP+ Sbjct 58 VESNDELHTLLSALPLFPYMKIHVTPLAKHPS 89 Score = 43.5 bits (101), Expect = 0.019, Method: Compositional matrix adjust. Identities = 27/89 (31%), Positives = 40/89 (45%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 FL+ + +P PA D+ ARE + +L +G + AL L+ Sbjct 3 FLVRMDVQIPHDLPAAEADEIKAREKAYSQDLQRQG---KWQALYRVVGEYANYSLFDVE 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L +LPL +M I TPL+ HP Sbjct 60 SNDELHTLLSALPLFPYMKIHVTPLAKHP 88 >gi|284043826|ref|YP_003394166.1| Muconolactone delta-isomerase [Conexibacter woesei DSM 14684] gi|283948047|gb|ADB50791.1| Muconolactone delta-isomerase [Conexibacter woesei DSM 14684] Length=91 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 38/91 (42%), Positives = 51/91 (57%), Gaps = 3/91 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV + +P M A+ +++ A E R REL A G + +WR P G R +G++ Sbjct 1 MEFLVDVRVSLPPEMAAEQRQQLLAAELKRGRELVAAGHIQGIWRIP---GAVRNVGIWN 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHP 91 A D EL QL+AS+P W DVT L HP Sbjct 58 ARDATELHQLIASLPLFPWLAADVTALATHP 88 Score = 62.0 bits (149), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 32/90 (36%), Positives = 48/90 (54%), Gaps = 3/90 (3%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRA 167 EFL+ + +PP A+ +A E +R EL GH+ +W +P R +G+W A Sbjct 2 EFLVDVRVSLPPEMAAEQRQQLLAAELKRGRELVAAGHIQGIWRIPGAV---RNVGIWNA 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 RD EL ++ SLPL W+ + T L+ HP Sbjct 59 RDATELHQLIASLPLFPWLAADVTALATHP 88 >gi|73541193|ref|YP_295713.1| muconolactone delta-isomerase [Ralstonia eutropha JMP134] gi|2808587|emb|CAA67959.1| methylmuconolactone isomerase [Ralstonia eutropha JMP134] gi|72118606|gb|AAZ60869.1| muconolactone delta-isomerase [Ralstonia eutropha JMP134] Length=91 Score = 65.9 bits (159), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 34/92 (37%), Positives = 50/92 (55%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M + V M +PDS+PAD E ++ E AR+ E+ GK LWR G + + +F Sbjct 1 MLYCVQMEVNIPDSLPADRAEAIKTAERARAIEIQKAGKWPHLWRV---AGRYANISVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 D + EL +LL+S+P + VTPL HP+ Sbjct 58 VDSHDELHELLSSLPLFPYMNIQVTPLARHPS 89 Score = 37.4 bits (85), Expect = 1.2, Method: Compositional matrix adjust. Identities = 24/89 (27%), Positives = 38/89 (43%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 + + + +P PA + E RA E+ G LW + + ++ Sbjct 3 YCVQMEVNIPDSLPADRAEAIKTAERARAIEIQKAGKWPHLWRVAGR---YANISVFDVD 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L SLPL +M I+ TPL+ HP Sbjct 60 SHDELHELLSSLPLFPYMNIQVTPLARHP 88 >gi|149375486|ref|ZP_01893256.1| Muconolactone delta-isomerase [Marinobacter algicola DG893] gi|149360191|gb|EDM48645.1| Muconolactone delta-isomerase [Marinobacter algicola DG893] Length=96 Score = 65.5 bits (158), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 50/92 (55%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +P MPAD V ++ARE A +++L +GK LWR G + + +F Sbjct 1 MLFKVEMKVNIPHDMPADVVADIKAREKAYAQDLQEKGKWRHLWRV---AGSYANVSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 +DN EL+ L+ ++P + V PL HP+ Sbjct 58 VEDNAELQDLVGNLPLFPYMDITVAPLCRHPS 89 Score = 47.0 bits (110), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/89 (31%), Positives = 40/89 (45%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 F + + +P PA VV D ARE A +L +G LW + + ++ Sbjct 3 FKVEMKVNIPHDMPADVVADIKAREKAYAQDLQEKGKWRHLWRV---AGSYANVSIFDVE 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 D EL ++ +LPL +M I PL HP Sbjct 60 DNAELQDLVGNLPLFPYMDITVAPLCRHP 88 >gi|325964841|ref|YP_004242747.1| muconolactone delta-isomerase [Arthrobacter phenanthrenivorans Sphe3] gi|323470928|gb|ADX74613.1| muconolactone delta-isomerase [Arthrobacter phenanthrenivorans Sphe3] Length=92 Score = 65.5 bits (158), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 32/93 (35%), Positives = 50/93 (54%), Gaps = 3/93 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M++LV M ++P +P D ++A+E A S+EL GK +WR GE+ +F Sbjct 1 MKYLVHMDVKLPADLPTDEAAGIKAKEKAYSQELQRSGKWPEIWR---VVGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPND 93 D N EL ++L ++P + V PL HP+D Sbjct 58 VDSNDELHEILQNLPLFPYMDISVVPLAKHPSD 90 Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust. Identities = 24/93 (26%), Positives = 40/93 (44%), Gaps = 5/93 (5%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWR 166 ++L+ + +P P A+E + EL G +W + G+ ++ Sbjct 2 KYLVHMDVKLPADLPTDEAAGIKAKEKAYSQELQRSGKWPEIWRVV----GEYANYSIFD 57 Query 167 ARDPGELMAILESLPLAGWMTIETTPLSPHPDD 199 EL IL++LPL +M I PL+ HP D Sbjct 58 VDSNDELHEILQNLPLFPYMDISVVPLAKHPSD 90 >gi|6014743|sp|O33947.1|CATC1_ACILW RecName: Full=Muconolactone Delta-isomerase 1; Short=MIase 1 gi|2335127|gb|AAC46227.1| muconolactone isomerase [Acinetobacter lwoffii K24] Length=96 Score = 65.5 bits (158), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 48/92 (53%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +PD MP + + ++ARE A S+ L GK +WR GE+ +F Sbjct 1 MLFHVRMDVNIPDDMPVEVADEIKAREKAYSQALQKSGKWPHIWR---LVGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N EL +L +P S+ +VTPL HP+ Sbjct 58 VESNAELHGILTGLPLFSYMKIEVTPLCRHPS 89 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/90 (32%), Positives = 39/90 (44%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +P P +V D+ ARE + L G +W L G+ ++ Sbjct 3 FHVRMDVNIPDDMPVEVADEIKAREKAYSQALQKSGKWPHIWRLV----GEYANYSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL IL LPL +M IE TPL HP Sbjct 59 ESNAELHGILTGLPLFSYMKIEVTPLCRHP 88 >gi|121592576|ref|YP_984472.1| muconolactone delta-isomerase [Acidovorax sp. JS42] gi|120604656|gb|ABM40396.1| muconolactone delta-isomerase [Acidovorax sp. JS42] Length=98 Score = 65.5 bits (158), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 34/98 (35%), Positives = 51/98 (53%), Gaps = 3/98 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M FLV M ++P +PA + ++ARE S++L G+ +WR GE+ +F Sbjct 1 MLFLVRMDVKIPHDLPAAQADEIKAREKKYSQDLQRDGRWRHIWRV---VGEYANYSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQG 98 N EL QLL+ +P + VTPL HP+ V +G Sbjct 58 VQSNDELHQLLSQLPLFPYMDIHVTPLANHPSAIVQEG 95 Score = 43.9 bits (102), Expect = 0.014, Method: Compositional matrix adjust. Identities = 26/90 (29%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 FL+ + +P PA D+ ARE + + +L G +W + G+ ++ Sbjct 3 FLVRMDVKIPHDLPAAQADEIKAREKKYSQDLQRDGRWRHIWRVV----GEYANYSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 + EL +L LPL +M I TPL+ HP Sbjct 59 QSNDELHQLLSQLPLFPYMDIHVTPLANHP 88 >gi|262368304|ref|ZP_06061633.1| muconolactone delta-isomerase [Acinetobacter johnsonii SH046] gi|262315982|gb|EEY97020.1| muconolactone delta-isomerase [Acinetobacter johnsonii SH046] Length=96 Score = 65.5 bits (158), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 48/92 (53%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +P MPA+ ++A E A S+EL AQGK +WR G++ + +F Sbjct 1 MLFHVRMDVNIPLDMPAETASEIKAVEKAYSQELQAQGKWRHIWRI---TGQYSNISIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 D N EL +L +P + +V PL HP+ Sbjct 58 VDSNEELHNILQGLPLYPYMNIEVMPLNRHPS 89 Score = 43.5 bits (101), Expect = 0.016, Method: Compositional matrix adjust. Identities = 26/90 (29%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRT-LGLWRA 167 F + + +P PA+ + A E + EL +G +W + GQ + + ++ Sbjct 3 FHVRMDVNIPLDMPAETASEIKAVEKAYSQELQAQGKWRHIWRIT----GQYSNISIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL IL+ LPL +M IE PL+ HP Sbjct 59 DSNEELHNILQGLPLYPYMNIEVMPLNRHP 88 >gi|296533379|ref|ZP_06895978.1| methylmuconolactone isomerase [Roseomonas cervicalis ATCC 49957] gi|296266305|gb|EFH12331.1| methylmuconolactone isomerase [Roseomonas cervicalis ATCC 49957] Length=97 Score = 65.1 bits (157), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 36/92 (40%), Positives = 51/92 (56%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P MPAD + +++RE A ++E+ QGK LWR G + + +F Sbjct 1 MLFHVAMQVRLPPDMPADRADALKSREKAVAQEIQRQGKWPHLWR---VAGRYANISIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 DN EL LL+S+P + VTPL HP+ Sbjct 58 VADNDELHALLSSLPLFPYMDITVTPLAQHPS 89 Score = 47.8 bits (112), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 30/89 (34%), Positives = 43/89 (49%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 F +A + +PP PA D +RE A E+ +G LW + + ++ Sbjct 3 FHVAMQVRLPPDMPADRADALKSREKAVAQEIQRQGKWPHLWRVAGR---YANISIFDVA 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 D EL A+L SLPL +M I TPL+ HP Sbjct 60 DNDELHALLSSLPLFPYMDITVTPLAQHP 88 >gi|182434156|ref|YP_001821875.1| putative methylmuconolactone isomerase [Streptomyces griseus subsp. griseus NBRC 13350] gi|178462672|dbj|BAG17192.1| putative methylmuconolactone isomerase [Streptomyces griseus subsp. griseus NBRC 13350] Length=131 Score = 64.3 bits (155), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 42/97 (44%), Positives = 52/97 (54%), Gaps = 11/97 (11%) Query 108 EFLIATTIMVP----PGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLG 163 EFL+ I P P +V DD E RRA ELA G LVR+W +P + G Sbjct 38 EFLVNIHITWPEAMDPDLKTKVSDD----ERRRAAELAASGTLVRMWRVPGRTEN---WG 90 Query 164 LWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDP 200 LWRA DP EL A++ SLP+ WM + L+ HP DP Sbjct 91 LWRAADPTELHAVISSLPVWPWMDVTVHALADHPVDP 127 Score = 61.2 bits (147), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 38/94 (41%), Positives = 50/94 (54%), Gaps = 3/94 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 MEFLV + P++M D +V E R+ ELAA G L+R+WR P R W GL+ Sbjct 37 MEFLVNIHITWPEAMDPDLKTKVSDDERRRAAELAASGTLVRMWRVPGRTENW---GLWR 93 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDP 94 A D EL +++S+P W V L HP DP Sbjct 94 AADPTELHAVISSLPVWPWMDVTVHALADHPVDP 127 >gi|345299626|ref|YP_004828984.1| muconolactone delta-isomerase [Enterobacter asburiae LF7a] gi|345093563|gb|AEN65199.1| muconolactone delta-isomerase [Enterobacter asburiae LF7a] Length=96 Score = 63.9 bits (154), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 49/92 (54%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V MT +P S+P + ++A+E A S+ L +GK L +WR G++ + +F Sbjct 1 MLFKVEMTVNIPASLPKVQADEIKAKEKAYSQRLQREGKWLHIWRV---VGQYANVSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 DN EL LL +P + V PL AHP+ Sbjct 58 VADNQELHTLLMELPLYPYMDITVQPLCAHPS 89 Score = 41.2 bits (95), Expect = 0.093, Method: Compositional matrix adjust. Identities = 25/90 (28%), Positives = 39/90 (44%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + T+ +P P D+ A+E + L G + +W + GQ + ++ Sbjct 3 FKVEMTVNIPASLPKVQADEIKAKEKAYSQRLQREGKWLHIWRVV----GQYANVSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 D EL +L LPL +M I PL HP Sbjct 59 ADNQELHTLLMELPLYPYMDITVQPLCAHP 88 >gi|254389169|ref|ZP_05004398.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 27064] gi|326444989|ref|ZP_08219723.1| muconolactone delta-isomerase [Streptomyces clavuligerus ATCC 27064] gi|37575593|gb|AAQ93582.1| putative muconolactone delta-isomerase [Streptomyces clavuligerus] gi|197702885|gb|EDY48697.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 27064] Length=97 Score = 63.9 bits (154), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 45/95 (48%), Positives = 56/95 (59%), Gaps = 6/95 (6%) Query 108 EFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQ-RTLGLWR 166 E+L+ T +P T + VD A EA RA ELA HL RLW P G+ R++G+WR Sbjct 3 EYLVEITTTIPEDTTPEEVDRRRAAEAVRARELAADSHLARLWR----PVGELRSIGIWR 58 Query 167 ARDPGELM-AILESLPLAGWMTIETTPLSPHPDDP 200 A D EL +L +LPL WMTI T L PHP+DP Sbjct 59 AADEDELHDKVLATLPLRPWMTITVTALEPHPNDP 93 Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 46/94 (49%), Positives = 62/94 (66%), Gaps = 4/94 (4%) Query 2 EFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAA 61 E+LV +TT +P+ + V+R RA EA R+RELAA L RLWRP GE R++G++ A Sbjct 3 EYLVEITTTIPEDTTPEEVDRRRAAEAVRARELAADSHLARLWRP---VGELRSIGIWRA 59 Query 62 DDNGEL-EQLLASMPPRSWRTDDVTPLGAHPNDP 94 D EL +++LA++P R W T VT L HPNDP Sbjct 60 ADEDELHDKVLATLPLRPWMTITVTALEPHPNDP 93 >gi|241663026|ref|YP_002981386.1| muconolactone delta-isomerase [Ralstonia pickettii 12D] gi|309782055|ref|ZP_07676785.1| muconolactone delta-isomerase [Ralstonia sp. 5_7_47FAA] gi|240865053|gb|ACS62714.1| muconolactone delta-isomerase [Ralstonia pickettii 12D] gi|308919121|gb|EFP64788.1| muconolactone delta-isomerase [Ralstonia sp. 5_7_47FAA] Length=96 Score = 63.9 bits (154), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 34/92 (37%), Positives = 48/92 (53%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P MPAD ++ARE A S++L GK +WR GE+ + +F Sbjct 1 MLFHVRMDVRLPADMPADVANEIKAREKAYSQDLQRSGKWRHIWR---LVGEYANVSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 N EL +L ++P + VTPL HP+ Sbjct 58 VQSNAELHDILTALPLFPYMEISVTPLCRHPS 89 Score = 42.4 bits (98), Expect = 0.046, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +P PA V ++ ARE + +L G +W L G+ + ++ Sbjct 3 FHVRMDVRLPADMPADVANEIKAREKAYSQDLQRSGKWRHIWRLV----GEYANVSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 + EL IL +LPL +M I TPL HP Sbjct 59 QSNAELHDILTALPLFPYMEISVTPLCRHP 88 >gi|187928449|ref|YP_001898936.1| muconolactone delta-isomerase [Ralstonia pickettii 12J] gi|187725339|gb|ACD26504.1| muconolactone delta-isomerase [Ralstonia pickettii 12J] Length=96 Score = 63.5 bits (153), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/92 (37%), Positives = 47/92 (52%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P MPAD ++ARE A S++L GK +WR GE+ +F Sbjct 1 MLFHVRMDVRLPADMPADVANEIKAREKAYSQDLQRSGKWRHIWR---LVGEYANYSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 N EL +L ++P + VTPL HP+ Sbjct 58 VQSNAELHDILTALPLFPYMEISVTPLCRHPS 89 Score = 42.0 bits (97), Expect = 0.048, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 41/90 (46%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +P PA V ++ ARE + +L G +W L G+ ++ Sbjct 3 FHVRMDVRLPADMPADVANEIKAREKAYSQDLQRSGKWRHIWRLV----GEYANYSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 + EL IL +LPL +M I TPL HP Sbjct 59 QSNAELHDILTALPLFPYMEISVTPLCRHP 88 >gi|325527352|gb|EGD04711.1| muconolactone delta-isomerase [Burkholderia sp. TJI49] Length=96 Score = 63.5 bits (153), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/92 (37%), Positives = 47/92 (52%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +P +PA + ++ARE A S+EL GK +WR GE+ +F Sbjct 1 MLFHVRMDVNLPADLPAGVADEIKAREKAYSQELQRSGKWRHIWRI---AGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 AD N EL +L +P + VTPL HP+ Sbjct 58 ADSNAELHDILTGLPLFPYMKISVTPLCRHPS 89 Score = 43.9 bits (102), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/90 (33%), Positives = 40/90 (45%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +P PA V D+ ARE + EL G +W + G+ ++ A Sbjct 3 FHVRMDVNLPADLPAGVADEIKAREKAYSQELQRSGKWRHIWRIA----GEYANYSIFDA 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL IL LPL +M I TPL HP Sbjct 59 DSNAELHDILTGLPLFPYMKISVTPLCRHP 88 >gi|300691535|ref|YP_003752530.1| muconolactone delta-isomerase (MIase) [Ralstonia solanacearum PSI07] gi|299078595|emb|CBJ51252.1| muconolactone delta-isomerase (MIase) [Ralstonia solanacearum PSI07] Length=96 Score = 62.8 bits (151), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 35/92 (39%), Positives = 51/92 (56%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P SMPAD ++A E ARS+ L +GK LWR G++ + +F Sbjct 1 MLFHVRMDVRLPPSMPADEAAALKATEKARSQALQTEGKWRHLWRI---AGQYANVSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + EL L++++P + T DV PL HP+ Sbjct 58 VESADELHALVSTLPLFPYMTIDVQPLCRHPS 89 Score = 40.4 bits (93), Expect = 0.16, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 40/90 (45%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +PP PA A E R+ L G LW + GQ + ++ Sbjct 3 FHVRMDVRLPPSMPADEAAALKATEKARSQALQTEGKWRHLWRIA----GQYANVSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL A++ +LPL +MTI+ PL HP Sbjct 59 ESADELHALVSTLPLFPYMTIDVQPLCRHP 88 >gi|160897312|ref|YP_001562894.1| muconolactone delta-isomerase [Delftia acidovorans SPH-1] gi|333916368|ref|YP_004490100.1| muconolactone delta-isomerase [Delftia sp. Cs1-4] gi|160362896|gb|ABX34509.1| muconolactone delta-isomerase [Delftia acidovorans SPH-1] gi|333746568|gb|AEF91745.1| muconolactone delta-isomerase [Delftia sp. Cs1-4] Length=92 Score = 62.4 bits (150), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 32/92 (35%), Positives = 48/92 (53%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M +LV M ++P +PAD ++ARE A S++L G+ +WR GE+ +F Sbjct 1 MLYLVRMDVKIPHDLPADVAAEIKAREKAYSQQLQHDGRWPHIWRV---VGEYANYSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 N EL +LL +P + VTPL HP+ Sbjct 58 VASNDELHELLQGLPLFPYMDIQVTPLARHPS 89 Score = 39.3 bits (90), Expect = 0.31, Method: Compositional matrix adjust. Identities = 25/90 (28%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 +L+ + +P PA V + ARE + +L G +W + G+ ++ Sbjct 3 YLVRMDVKIPHDLPADVAAEIKAREKAYSQQLQHDGRWPHIWRVV----GEYANYSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L+ LPL +M I+ TPL+ HP Sbjct 59 ASNDELHELLQGLPLFPYMDIQVTPLARHP 88 >gi|238024139|ref|YP_002908371.1| Muconolactone Delta-isomerase [Burkholderia glumae BGR1] gi|237878804|gb|ACR31136.1| Muconolactone Delta-isomerase [Burkholderia glumae BGR1] Length=96 Score = 62.4 bits (150), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 49/92 (54%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +P +PAD + ++ RE A S+EL GK +WR GE+ + +F Sbjct 1 MLFHVRMDVNLPADLPADVADAIKLREKAYSQELQRSGKWRHIWRI---VGEYANVSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N EL +LL ++P + T V PL HP+ Sbjct 58 VESNAELHELLTALPLFPYMTISVMPLCRHPS 89 Score = 39.3 bits (90), Expect = 0.37, Method: Compositional matrix adjust. Identities = 26/90 (29%), Positives = 39/90 (44%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +P PA V D RE + EL G +W + G+ + ++ Sbjct 3 FHVRMDVNLPADLPADVADAIKLREKAYSQELQRSGKWRHIWRIV----GEYANVSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L +LPL +MTI PL HP Sbjct 59 ESNAELHELLTALPLFPYMTISVMPLCRHP 88 >gi|158423963|ref|YP_001525255.1| methylmuconolactone isomerase [Azorhizobium caulinodans ORS 571] gi|158330852|dbj|BAF88337.1| methylmuconolactone isomerase [Azorhizobium caulinodans ORS 571] Length=91 Score = 62.4 bits (150), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 49/92 (54%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +P PA+ + ++A E A +++L QGK L LWR G + + +F Sbjct 1 MLFHVEMQVNIPHDFPAEKADAIKAAEKAYAQDLQRQGKWLHLWRI---AGRYANVSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + EL QLL+S+P + VTPL HP+ Sbjct 58 VESVDELHQLLSSLPLFPFMDIKVTPLARHPS 89 Score = 42.4 bits (98), Expect = 0.045, Method: Compositional matrix adjust. Identities = 26/89 (30%), Positives = 41/89 (47%), Gaps = 3/89 (3%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRAR 168 F + + +P PA+ D A E A +L +G + LW + + ++ Sbjct 3 FHVEMQVNIPHDFPAEKADAIKAAEKAYAQDLQRQGKWLHLWRIAGR---YANVSIFDVE 59 Query 169 DPGELMAILESLPLAGWMTIETTPLSPHP 197 EL +L SLPL +M I+ TPL+ HP Sbjct 60 SVDELHQLLSSLPLFPFMDIKVTPLARHP 88 >gi|344166822|emb|CCA79010.1| muconolactone delta-isomerase (MIase) [blood disease bacterium R229] Length=96 Score = 62.4 bits (150), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 35/92 (39%), Positives = 51/92 (56%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P SMPAD ++A E ARS+ L +GK LWR G++ + +F Sbjct 1 MLFHVRMDVRLPPSMPADEAAALKATEKARSQALQTEGKWRHLWRI---AGQYANVSVFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + EL L++++P + T DV PL HP+ Sbjct 58 VESADELHALVSTLPLFPYMTIDVQPLCRHPS 89 Score = 40.0 bits (92), Expect = 0.19, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 40/90 (45%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +PP PA A E R+ L G LW + GQ + ++ Sbjct 3 FHVRMDVRLPPSMPADEAAALKATEKARSQALQTEGKWRHLWRIA----GQYANVSVFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL A++ +LPL +MTI+ PL HP Sbjct 59 ESADELHALVSTLPLFPYMTIDVQPLCRHP 88 >gi|23491544|dbj|BAC16776.1| muconolactone isomerase [Burkholderia sp. TH2] Length=92 Score = 62.0 bits (149), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 34/92 (37%), Positives = 49/92 (54%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M +LV M +P+ MP + ++ARE A S+EL QGK +L R GE+ +F Sbjct 1 MLYLVRMDVHLPNDMPMAQADEIKAREKAYSQELQRQGKWQQLHRV---VGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N EL +LA +P + T VT L HP+ Sbjct 58 VESNDELHTILAGLPLFPYMTMKVTALARHPS 89 Score = 36.6 bits (83), Expect = 2.0, Method: Compositional matrix adjust. Identities = 25/90 (28%), Positives = 39/90 (44%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 +L+ + +P P D+ ARE + EL +G W G+ ++ Sbjct 3 YLVRMDVHLPNDMPMAQADEIKAREKAYSQELQRQGK----WQQLHRVVGEYANYSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 EL IL LPL +MT++ T L+ HP Sbjct 59 ESNDELHTILAGLPLFPYMTMKVTALARHP 88 >gi|334195978|gb|AEG69163.1| muconolactone delta-isomerase [Ralstonia solanacearum Po82] Length=96 Score = 61.6 bits (148), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 34/92 (37%), Positives = 53/92 (58%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P S+PA+ ++A E ARS+ L A+GK LWR G++ + +F Sbjct 1 MLFHVRMDVRLPPSLPAEEAAALKATEKARSQALQAEGKWRHLWRI---AGQYANVSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 ++ EL L++++P + T DV PL HP+ Sbjct 58 VENADELHALVSTLPLFPYMTIDVQPLCRHPS 89 Score = 42.7 bits (99), Expect = 0.031, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +PP PA+ A E R+ L G LW + GQ + ++ Sbjct 3 FHVRMDVRLPPSLPAEEAAALKATEKARSQALQAEGKWRHLWRIA----GQYANVSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 + EL A++ +LPL +MTI+ PL HP Sbjct 59 ENADELHALVSTLPLFPYMTIDVQPLCRHP 88 >gi|187476821|ref|YP_784845.1| methylmuconolactone isomerase [Bordetella avium 197N] gi|115421407|emb|CAJ47912.1| methylmuconolactone isomerase [Bordetella avium 197N] Length=91 Score = 61.6 bits (148), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 32/92 (35%), Positives = 52/92 (57%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M ++V M +P MPAD ++++A E A +++L +GK LWR G + + +F Sbjct 1 MLYMVEMQVNLPVDMPADKADKLKADEKALAQKLQHEGKWQSLWRV---VGRYANVSIFN 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 D++ EL QLL+S+P + VT L HP+ Sbjct 58 VDNHDELHQLLSSLPLFPYMDIRVTALARHPS 89 Score = 36.6 bits (83), Expect = 2.3, Method: Compositional matrix adjust. Identities = 25/90 (28%), Positives = 40/90 (45%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 +++ + +P PA D A E A +L G LW + G+ + ++ Sbjct 3 YMVEMQVNLPVDMPADKADKLKADEKALAQKLQHEGKWQSLWRVV----GRYANVSIFNV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 + EL +L SLPL +M I T L+ HP Sbjct 59 DNHDELHQLLSSLPLFPYMDIRVTALARHP 88 >gi|38638065|ref|NP_943039.1| putative muconolactone isomerase [Ralstonia eutropha H16] gi|32527403|gb|AAP86153.1| putative muconolactone isomerase [Ralstonia eutropha H16] Length=92 Score = 61.6 bits (148), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 33/92 (36%), Positives = 50/92 (55%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M +LV M +P MPA + ++ARE A +++L QGK +L+R GE+ +F Sbjct 1 MLYLVRMDVNLPHDMPAAQADEIKAREKAYAQDLQRQGKWQQLYRV---VGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N +L LLA +P + VTPL HP+ Sbjct 58 VESNDKLHTLLAGLPLFPYMKLAVTPLAKHPS 89 Score = 37.4 bits (85), Expect = 1.5, Method: Compositional matrix adjust. Identities = 24/90 (27%), Positives = 42/90 (47%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 +L+ + +P PA D+ ARE A +L +G +L+ + G+ ++ Sbjct 3 YLVRMDVNLPHDMPAAQADEIKAREKAYAQDLQRQGKWQQLYRVV----GEYANYSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 +L +L LPL +M + TPL+ HP Sbjct 59 ESNDKLHTLLAGLPLFPYMKLAVTPLAKHP 88 >gi|307725880|ref|YP_003909093.1| muconolactone delta-isomerase [Burkholderia sp. CCGE1003] gi|307586405|gb|ADN59802.1| muconolactone delta-isomerase [Burkholderia sp. CCGE1003] Length=96 Score = 61.6 bits (148), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 31/92 (34%), Positives = 47/92 (52%), Gaps = 3/92 (3%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M +P MPA + +R+RE A ++EL GK +WR GE+ +F Sbjct 1 MLFHVRMDVNLPPDMPAHIADEIRSREKAYAQELQKSGKWRHIWRV---AGEYANYSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92 + N +L +L +P ++ VTPL HP+ Sbjct 58 VESNAQLHDILVGLPLFAYMKISVTPLCRHPS 89 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 40/90 (45%), Gaps = 5/90 (5%) Query 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167 F + + +PP PA + D+ +RE A EL G +W + G+ ++ Sbjct 3 FHVRMDVNLPPDMPAHIADEIRSREKAYAQELQKSGKWRHIWRVA----GEYANYSIFDV 58 Query 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197 +L IL LPL +M I TPL HP Sbjct 59 ESNAQLHDILVGLPLFAYMKISVTPLCRHP 88 >gi|118471569|ref|YP_886278.1| muconolactone delta-isomerase 1 [Mycobacterium smegmatis str. MC2 155] gi|5305775|gb|AAD41808.1|AF144091_2 muconolactone isomerase [Mycobacterium smegmatis str. MC2 155] gi|118172856|gb|ABK73752.1| muconolactone delta-isomerase 1 [Mycobacterium smegmatis str. MC2 155] Length=94 Score = 61.6 bits (148), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 34/98 (35%), Positives = 51/98 (53%), Gaps = 4/98 (4%) Query 1 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60 M F V M R+P M D + ++ ARE A S++L GK +WR GE+ +F Sbjct 1 MHFHVRMDVRLPHDMDQDTLAQLVAREKAYSQQLQRSGKWPHIWRI---VGEYANFSIFD 57 Query 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQG 98 + N EL +++ +P + VTPL HP+D + QG Sbjct 58 VETNDELHSVISGLPLFPYMDIHVTPLARHPSD-IDQG 94 Lambda K H 0.318 0.137 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 226797436674 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40