BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0327c Length=449 Score E Sequences producing significant alignments: (Bits) Value gi|15607468|ref|NP_214841.1| cytochrome P450 135A1 [Mycobacteriu... 912 0.0 gi|148821523|ref|YP_001286277.1| cytochrome P450 135A1 cyp135A1 ... 910 0.0 gi|31791505|ref|NP_853998.1| cytochrome P450 135A1 [Mycobacteriu... 910 0.0 gi|289441707|ref|ZP_06431451.1| cytochrome P450 135A1 cyp135A1 [... 910 0.0 gi|289748096|ref|ZP_06507474.1| cytochrome P450 135A1 [Mycobacte... 909 0.0 gi|339630401|ref|YP_004722043.1| cytochrome P450 [Mycobacterium ... 909 0.0 gi|119718594|ref|YP_925559.1| cytochrome P450 [Nocardioides sp. ... 446 3e-123 gi|311743314|ref|ZP_07717121.1| P450 heme-thiolate protein [Aero... 414 1e-113 gi|257056229|ref|YP_003134061.1| cytochrome P450 [Saccharomonosp... 381 2e-103 gi|284028900|ref|YP_003378831.1| cytochrome P450 [Kribbella flav... 362 8e-98 gi|333920661|ref|YP_004494242.1| cytochrome P450 [Amycolicicoccu... 353 2e-95 gi|319948572|ref|ZP_08022701.1| cytochrome P450 [Dietzia cinname... 323 3e-86 gi|120402053|ref|YP_951882.1| cytochrome P450 [Mycobacterium van... 310 5e-82 gi|108797764|ref|YP_637961.1| cytochrome P450 [Mycobacterium sp.... 302 6e-80 gi|315442488|ref|YP_004075367.1| cytochrome P450 [Mycobacterium ... 302 7e-80 gi|126433391|ref|YP_001069082.1| cytochrome P450 [Mycobacterium ... 301 2e-79 gi|118467999|ref|YP_885605.1| cytochrome P450 monooxygenase [Myc... 295 8e-78 gi|340625595|ref|YP_004744047.1| putative cytochrome P450 135B1 ... 293 4e-77 gi|240169264|ref|ZP_04747923.1| cytochrome P450 135B4 Cyp135B4 [... 291 1e-76 gi|183980959|ref|YP_001849250.1| cytochrome P450 135B4 Cyp135B4 ... 291 2e-76 gi|296168352|ref|ZP_06850276.1| P450 heme-thiolate protein [Myco... 288 1e-75 gi|121636486|ref|YP_976709.1| putative cytochrome p450 135b1 cyp... 278 1e-72 gi|15607708|ref|NP_215082.1| cytochrome P450 135B1 [Mycobacteriu... 277 2e-72 gi|289446115|ref|ZP_06435859.1| cytochrome P450 135B1 cyp135B1 [... 275 1e-71 gi|169631766|ref|YP_001705415.1| cytochrome P450 [Mycobacterium ... 274 2e-71 gi|183982980|ref|YP_001851271.1| cytochrome P450 135B6 Cyp135B6 ... 274 2e-71 gi|167968359|ref|ZP_02550636.1| cytochrome P450 135B1 cyp135B1 [... 273 3e-71 gi|183984453|ref|YP_001852744.1| cytochrome P450 135B3 Cyp135B3 ... 270 4e-70 gi|296394390|ref|YP_003659274.1| cytochrome P450 [Segniliparus r... 263 4e-68 gi|284041673|ref|YP_003392013.1| cytochrome P450 [Conexibacter w... 259 6e-67 gi|284041826|ref|YP_003392166.1| cytochrome P450 [Conexibacter w... 252 8e-65 gi|308372935|ref|ZP_07430431.2| cytochrome P450 135B1 cyp135B1 [... 252 9e-65 gi|254823430|ref|ZP_05228431.1| cytochrome P450 family protein [... 251 1e-64 gi|256377230|ref|YP_003100890.1| cytochrome P450 [Actinosynnema ... 246 6e-63 gi|254416685|ref|ZP_05030435.1| Cytochrome P450 superfamily [Mic... 246 6e-63 gi|186683024|ref|YP_001866220.1| cytochrome P450 [Nostoc punctif... 246 7e-63 gi|186684527|ref|YP_001867723.1| cytochrome P450 [Nostoc punctif... 245 1e-62 gi|342860591|ref|ZP_08717242.1| cytochrome P450 [Mycobacterium c... 245 1e-62 gi|119512554|ref|ZP_01631632.1| Cytochrome P450 [Nodularia spumi... 244 2e-62 gi|307153475|ref|YP_003888859.1| cytochrome P450 [Cyanothece sp.... 241 2e-61 gi|17231238|ref|NP_487786.1| cytochrome P450 [Nostoc sp. PCC 712... 240 4e-61 gi|158334010|ref|YP_001515182.1| cytochrome P450 family protein ... 240 4e-61 gi|254416793|ref|ZP_05030542.1| Cytochrome P450 superfamily [Mic... 239 5e-61 gi|284045204|ref|YP_003395544.1| cytochrome P450 [Conexibacter w... 239 6e-61 gi|119485435|ref|ZP_01619763.1| cytochrome P450 [Lyngbya sp. PCC... 238 1e-60 gi|218438521|ref|YP_002376850.1| cytochrome P450 [Cyanothece sp.... 236 6e-60 gi|119510163|ref|ZP_01629302.1| cytochrome P450 [Nodularia spumi... 236 6e-60 gi|186683878|ref|YP_001867074.1| cytochrome P450 [Nostoc punctif... 236 7e-60 gi|166364998|ref|YP_001657271.1| cytochrome P450 [Microcystis ae... 235 1e-59 gi|159028471|emb|CAO87278.1| cyp110A2 [Microcystis aeruginosa PC... 234 2e-59 >gi|15607468|ref|NP_214841.1| cytochrome P450 135A1 [Mycobacterium tuberculosis H37Rv] gi|15839714|ref|NP_334751.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|148660093|ref|YP_001281616.1| putative cytochrome p450 135A1 Cyp135A1 [Mycobacterium tuberculosis H37Ra] 60 more sequence titles Length=449 Score = 912 bits (2356), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/449 (100%), Positives = 449/449 (100%), Gaps = 0/449 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP Sbjct 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR Sbjct 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI Sbjct 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK Sbjct 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL Sbjct 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP Sbjct 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR Sbjct 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 Query 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 NITTVPKHGAHLRLIPQRRLGGLGDSDPP Sbjct 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 >gi|148821523|ref|YP_001286277.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis F11] gi|148720050|gb|ABR04675.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis F11] Length=449 Score = 910 bits (2352), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/449 (99%), Positives = 448/449 (99%), Gaps = 0/449 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP Sbjct 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR Sbjct 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI Sbjct 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK Sbjct 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL Sbjct 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP Sbjct 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 SRFLDGSVAPNTWLPFG GVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR Sbjct 361 SRFLDGSVAPNTWLPFGSGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 Query 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 NITTVPKHGAHLRLIPQRRLGGLGDSDPP Sbjct 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 >gi|31791505|ref|NP_853998.1| cytochrome P450 135A1 [Mycobacterium bovis AF2122/97] gi|121636241|ref|YP_976464.1| putative cytochrome P450 135A1 cyp135A1 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988714|ref|YP_002643401.1| putative cytochrome P450 135A1 [Mycobacterium bovis BCG str. Tokyo 172] gi|31617091|emb|CAD93198.1| POSSIBLE CYTOCHROME P450 135A1 CYP135A1 [Mycobacterium bovis AF2122/97] gi|121491888|emb|CAL70351.1| Possible cytochrome P450 135A1 cyp135A1 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224771827|dbj|BAH24633.1| putative cytochrome P450 135A1 [Mycobacterium bovis BCG str. Tokyo 172] gi|341600257|emb|CCC62927.1| possible cytochrome P450 135A1 cyp135A1 [Mycobacterium bovis BCG str. Moreau RDJ] Length=449 Score = 910 bits (2351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/449 (99%), Positives = 449/449 (100%), Gaps = 0/449 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP Sbjct 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAE+ARMRSLLMPAFTRAALRGYR Sbjct 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEYARMRSLLMPAFTRAALRGYR 120 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI Sbjct 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK Sbjct 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL Sbjct 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP Sbjct 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR Sbjct 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 Query 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 NITTVPKHGAHLRLIPQRRLGGLGDSDPP Sbjct 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 >gi|289441707|ref|ZP_06431451.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis T46] gi|289568238|ref|ZP_06448465.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis T17] gi|289748810|ref|ZP_06508188.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis T92] gi|289752357|ref|ZP_06511735.1| cytochrome P450 135A1 [Mycobacterium tuberculosis EAS054] gi|289414626|gb|EFD11866.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis T46] gi|289541991|gb|EFD45640.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis T17] gi|289689397|gb|EFD56826.1| cytochrome P450 135A1 cyp135A1 [Mycobacterium tuberculosis T92] gi|289692944|gb|EFD60373.1| cytochrome P450 135A1 [Mycobacterium tuberculosis EAS054] Length=449 Score = 910 bits (2351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/449 (99%), Positives = 449/449 (100%), Gaps = 0/449 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPA+HRKYGDVFSLRVPPYADNLVVYTRP Sbjct 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAIHRKYGDVFSLRVPPYADNLVVYTRP 60 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR Sbjct 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI Sbjct 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK Sbjct 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL Sbjct 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP Sbjct 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR Sbjct 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 Query 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 NITTVPKHGAHLRLIPQRRLGGLGDSDPP Sbjct 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 >gi|289748096|ref|ZP_06507474.1| cytochrome P450 135A1 [Mycobacterium tuberculosis 02_1987] gi|289688624|gb|EFD56112.1| cytochrome P450 135A1 [Mycobacterium tuberculosis 02_1987] Length=449 Score = 909 bits (2350), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/449 (99%), Positives = 448/449 (99%), Gaps = 0/449 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP Sbjct 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR Sbjct 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI Sbjct 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIAS RIDSDLTARTDVLSRLLQTK Sbjct 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASHRIDSDLTARTDVLSRLLQTK 240 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL Sbjct 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP Sbjct 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR Sbjct 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 Query 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 NITTVPKHGAHLRLIPQRRLGGLGDSDPP Sbjct 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 >gi|339630401|ref|YP_004722043.1| cytochrome P450 [Mycobacterium africanum GM041182] gi|339329757|emb|CCC25401.1| putative cytochrome P450 135A1 CYP135A1 [Mycobacterium africanum GM041182] Length=449 Score = 909 bits (2348), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/449 (99%), Positives = 448/449 (99%), Gaps = 0/449 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP Sbjct 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 EHIKEIFAADPRSLHAGEGNHILGFVM EHSVLMTDEAEHARMRSLLMPAFTRAALRGYR Sbjct 61 EHIKEIFAADPRSLHAGEGNHILGFVMREHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI Sbjct 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK Sbjct 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL Sbjct 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP Sbjct 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR Sbjct 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 Query 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 NITTVPKHGAHLRLIPQRRLGGLGDSDPP Sbjct 421 NITTVPKHGAHLRLIPQRRLGGLGDSDPP 449 >gi|119718594|ref|YP_925559.1| cytochrome P450 [Nocardioides sp. JS614] gi|119539255|gb|ABL83872.1| cytochrome P450 [Nocardioides sp. JS614] Length=464 Score = 446 bits (1148), Expect = 3e-123, Method: Compositional matrix adjust. Identities = 228/430 (54%), Positives = 283/430 (66%), Gaps = 5/430 (1%) Query 7 TGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEI 66 +GLPPGPR P +Q+ LRFR F P +HRKYGD F++R+ P LV +TRPEH KEI Sbjct 32 SGLPPGPRWPVLVQTAGLLRFRHRFHPYLHRKYGDAFTVRLAPGGRPLVFFTRPEHAKEI 91 Query 67 FAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASV 126 FA DP HAG+ N ILG +MGEHS+L+ D EH R R LLMPAF ALR Y+ ++ V Sbjct 92 FAGDPEVFHAGKANGILGPIMGEHSLLLQDSREHKRARKLLMPAFNGHALREYQALVTEV 151 Query 127 AREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILA 186 AR + WR +LD MNALTL++ILRVVFGVTD A L R+ + +NI PAIL Sbjct 152 ARAEVGGWRSGQEFRALDRMNALTLEVILRVVFGVTDEARLARLRPRVNKTVNISPAILL 211 Query 187 GVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKP 246 G YP L+R PWK NQ ++D ++Y EI RR +DL RTDVLSRL+ D+ Sbjct 212 GWGYPWLQRFGPWKATVDNQRELDRLMYAEIRDRRTATDLAERTDVLSRLILQGDSGESG 271 Query 247 --LTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVL 304 L+D ELRDQL+TLLLAGHETTA+ALSW L+E P + ++ AA GGDD FLEAVL Sbjct 272 DRLSDTELRDQLVTLLLAGHETTASALSWALYETGRDPGLLARCQRAAAGGDDDFLEAVL 331 Query 305 KEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFL 364 KE MR H +I R + PA I GW LP GT V SI++AH E +HP P FRP RFL Sbjct 332 KEAMRLHPIIPMVVRTLMEPATIAGWDLPRGTTVGPSIIIAHQREDNHPDPDVFRPERFL 391 Query 365 DGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITT 424 + NTW+PFGGGVRRCLG GF+L EG +L+E+F + + A G + P VRNIT+ Sbjct 392 GQNPPANTWIPFGGGVRRCLGAGFSLMEGVAVLREVFAAYDVEALGRDE---PKVRNITS 448 Query 425 VPKHGAHLRL 434 VP+ G +R+ Sbjct 449 VPRRGTRIRV 458 >gi|311743314|ref|ZP_07717121.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272] gi|311313382|gb|EFQ83292.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272] Length=438 Score = 414 bits (1065), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 217/430 (51%), Positives = 277/430 (65%), Gaps = 3/430 (0%) Query 8 GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIF 67 G+P GPR + + ++R R+ +P +H +YGD FSL++ P VV++ P +KEIF Sbjct 12 GIPAGPRGSVWRTTWRFMRDRKELIPRLHEQYGDTFSLQIMPGPRTFVVFSDPADVKEIF 71 Query 68 AADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 AADP HAGEGN ILG VMGE+SVL+ D+A H R R LLMPAF+ A +RGY ++ +VA Sbjct 72 AADPAQFHAGEGNAILGPVMGENSVLLVDDAAHQRARKLLMPAFSGAPMRGYVPLVEAVA 131 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 + + W T+ +LD MNA+TL+IILRVVFGVTDP L + ++++I +L Sbjct 132 KAEVDSWDASRTLVTLDRMNAITLEIILRVVFGVTDPARLDALRPMVNRMVDIDAKMLLA 191 Query 188 VPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPL 247 YP L + PW+ +F NQ +DE+LY EI RR +DL R DVLSRLL+ T PL Sbjct 192 WSYPRLAAVPPWRGYFRNQAAVDELLYAEIRERRAATDLDVRDDVLSRLLRVGGDDTAPL 251 Query 248 TDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLKEG 307 TD ELRDQL+TLLLAGHETTA+ALSWTL EL PE + AA GDD +LEA LKE Sbjct 252 TDTELRDQLVTLLLAGHETTASALSWTLHELGRDPERHALATAAADEGDDAYLEACLKEA 311 Query 308 MRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGS 367 MR H VI AR + + +GG RLP G V SI+L+H+ E S FRP RF G Sbjct 312 MRLHPVIDFVARTLQSEQVVGGRRLPRGVTVTPSIMLSHSREQSFADAHLFRPERFTAGE 371 Query 368 VAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPK 427 VAPNTW+PFGGG RRCLG F+L EG V+L+E+ R T+ A P+ L+RNIT VP Sbjct 372 VAPNTWIPFGGGARRCLGAAFSLMEGTVVLREVLLRHTVHADRPAPN---LLRNITNVPG 428 Query 428 HGAHLRLIPQ 437 A L L P+ Sbjct 429 DRAPLTLTPR 438 >gi|257056229|ref|YP_003134061.1| cytochrome P450 [Saccharomonospora viridis DSM 43017] gi|256586101|gb|ACU97234.1| cytochrome P450 [Saccharomonospora viridis DSM 43017] Length=451 Score = 381 bits (978), Expect = 2e-103, Method: Compositional matrix adjust. Identities = 212/431 (50%), Positives = 267/431 (62%), Gaps = 4/431 (0%) Query 10 PPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAA 69 PPGPRLP Q++L+ FR+++LP + R+YGD+ LR+ P ++V+ + EHI+ +FA Sbjct 21 PPGPRLPVAAQTILFGSFRQYWLPRLRRRYGDIVRLRIYP-KRSVVLLSDVEHIRAVFAG 79 Query 70 DPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVARE 129 HAGEGN IL VMGEHSVL+TDEA H R R LLMPAF AALRGYRDMI +A Sbjct 80 PASVFHAGEGNVILKPVMGEHSVLLTDEAVHLRARKLLMPAFNGAALRGYRDMITELAEA 139 Query 130 HITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGVP 189 + RW + +S M LTL++ILRVVFGV + EL L++I+++ P L G Sbjct 140 EVRRWPSNRVFSSHVRMQELTLEVILRVVFGVAEGPRLDELRHLLRRIVDVTPFDLLGWH 199 Query 190 YPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLL--QTKDTPTKPL 247 P L+ PW+R+ Q ++D +LY EIA RR DL R DVLSRLL + PL Sbjct 200 NPKLQSFGPWRRYALVQRRVDRLLYTEIAERRRAKDLADRRDVLSRLLTVSARAENETPL 259 Query 248 TDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLKEG 307 TDAELRDQLITLLLAGHETTA AL+W L EL P + AA GDD +LEAV+KE Sbjct 260 TDAELRDQLITLLLAGHETTATALAWALHELVRDPAAFDRAAQAADEGDDKYLEAVVKEA 319 Query 308 MRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGS 367 MR H VI+ AR++T +IG R+P G V SI L HA HP P FRP RFL Sbjct 320 MRLHPVISEVARRLTRDIQIGDIRIPKGHTVMPSISLVHADPAHHPDPKRFRPERFLGSG 379 Query 368 VAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPK 427 A TW PFGGGVRRCLG GF+L E ++L+ I + P++ T RNIT VP Sbjct 380 PASGTWFPFGGGVRRCLGAGFSLLESVIMLRAILTHHRLAPDRPNREHTK-PRNITMVPA 438 Query 428 HGAHLRLIPQR 438 GA + P++ Sbjct 439 RGARVVATPRK 449 >gi|284028900|ref|YP_003378831.1| cytochrome P450 [Kribbella flavida DSM 17836] gi|283808193|gb|ADB30032.1| cytochrome P450 [Kribbella flavida DSM 17836] Length=443 Score = 362 bits (928), Expect = 8e-98, Method: Compositional matrix adjust. Identities = 193/430 (45%), Positives = 260/430 (61%), Gaps = 9/430 (2%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LPPGP+ P +Q+VL+ R+ F P M +YGDVF++R+ P + +VV +RPE I+++F Sbjct 21 LPPGPKWPTLVQTVLFAGHRKTFFPRMRARYGDVFTIRLVPSSRVVVVLSRPEDIRDVFT 80 Query 69 ADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAR 128 P +HAGEGN +L +MG+HS+L+ D+ +HAR R LMPAF ALRGY MIA +AR Sbjct 81 TPPTVMHAGEGNQVLKPIMGDHSLLLIDDEDHARTRRQLMPAFLGNALRGYAGMIADLAR 140 Query 129 EHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGV 188 + W D M LTL++IL+VVFGVTD AEL + +I+ + P I+ G Sbjct 141 AEVESWPVGQPFRLHDRMRDLTLEVILQVVFGVTDSARLAELRPLVDRIVAVRPIIMLGG 200 Query 189 PYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLT 248 YP L R+ PW+ + Q ++DEILY EIA RR D+ R DVLSRLL + Sbjct 201 FYPQLLRLPPWRTYLETQRRVDEILYDEIARRR--DDVAGRNDVLSRLLAAGS-----WS 253 Query 249 DAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLKEGM 308 D ELRDQL+TLLLAGHETTA L+W ELA P+ + AA GDD LEA+ KE + Sbjct 254 DVELRDQLVTLLLAGHETTATGLAWAFHELARRPDELAAAQRAADSGDDERLEAITKESL 313 Query 309 RRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFL-DGS 367 R H V+ R++T ++ G+RLP GT + ++ L HA +P EFRP RFL + Sbjct 314 RLHPVVYQVGRRLTETVDLAGYRLPRGTTIMAALGLVHADGEHYPAAGEFRPDRFLSEDP 373 Query 368 VAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPK 427 A TW+PFGGG RRC+G GF+L E IL+ R+ + P ET RN+T VP Sbjct 374 PAAGTWIPFGGGARRCIGAGFSLLEATEILRATLSRYDVHPVRPEP-ETAQPRNVTLVPS 432 Query 428 HGAHLRLIPQ 437 G + + P+ Sbjct 433 RGCEVVVTPR 442 >gi|333920661|ref|YP_004494242.1| cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] gi|333482882|gb|AEF41442.1| Cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] Length=439 Score = 353 bits (907), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 206/440 (47%), Positives = 270/440 (62%), Gaps = 14/440 (3%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M T+ +PPGPRLP +Q+ + R R ++P + ++YGDVFSL V P +LV P Sbjct 1 MTQTMRLDVPPGPRLPLAIQTWRFARSRHEWIPELRKRYGDVFSLSVYPQR-HLVQLAHP 59 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 + I+ +F P HAGEGN IL ++GE SVL TDE +H R+R LLMP F ALRGYR Sbjct 60 DDIRAVFGGPPDLFHAGEGNMILTPIVGEQSVLTTDEDQHRRLRGLLMPPFHGQALRGYR 119 Query 121 DMIASVAREHITRW---RPHATINSLDHMNALTLDIILRVVFGVTD-PKVKAELTSRLQQ 176 +M+A++A + +RW RP AT + M ALTL+II+RVVFGV + P++ A L L + Sbjct 120 NMVAALAIDDASRWPVGRPFATHS---RMQALTLEIIMRVVFGVAEGPRLDA-LRDLLGR 175 Query 177 IINIHPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRL 236 +++++ L GV P L+R PW+R Q +ID +L EI+ RR +DL R DVLS+L Sbjct 176 LVSLNLLSLFGVHDPRLRRFGPWRRTVGMQREIDALLGSEISERRRATDLADRPDVLSQL 235 Query 237 LQTKDTPTKP----LTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAA 292 + LTDAELRDQLITLLLAGHETTA AL+W ELA PE Q AA Sbjct 236 IAGSSAAAGTASDGLTDAELRDQLITLLLAGHETTATALAWAFHELARDPERQRLGREAA 295 Query 293 VGGDDGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSH 352 + GDD +LEA+ KE +R VI AR +T EI G+R+PAG V I + + H Sbjct 296 LNGDDKYLEAIFKEALRLRPVIYEVARTLTEDIEIRGFRIPAGYTVMPMIGVVQSDPEHH 355 Query 353 PKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPS 412 P FRP RFL+GS APNTW+PFGGGVRRCLG GFA EG +L+ + R+T + Sbjct 356 EDPELFRPERFLNGSPAPNTWIPFGGGVRRCLGAGFAQMEGTEVLRAVLSRYTFMPDRVA 415 Query 413 KGETPLVRNITTVPKHGAHL 432 E + RNIT P+ G + Sbjct 416 P-ERAVPRNITLTPRRGGRI 434 >gi|319948572|ref|ZP_08022701.1| cytochrome P450 [Dietzia cinnamea P4] gi|319437771|gb|EFV92762.1| cytochrome P450 [Dietzia cinnamea P4] Length=486 Score = 323 bits (829), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 179/437 (41%), Positives = 255/437 (59%), Gaps = 1/437 (0%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M S + LPPGPR PR LQ+VL L PA R+YG F+L + P +V + P Sbjct 51 MISDVAHRLPPGPRAPRLLQAVLALAAPAAVFPAAARRYGVPFTLDLMPRGRKVVAVSEP 110 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 +K++FA P HAG+GN +L ++G+HS+L+ D EHAR R LL PAF R + GYR Sbjct 111 AQVKDVFAGSPSVFHAGKGNDLLRPLLGDHSLLLQDGDEHARARRLLAPAFGRREIAGYR 170 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 +++ V E + RW + + +N LTL++ILRVVFGVTD + + + ++ Sbjct 171 ELVEEVTAEQLARWPRSGRVRAHVLLNQLTLEVILRVVFGVTDSARLDRMRPIVARAVDA 230 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 P ++ G+ L+R+ PW R + I E L EI + R D L R D+++ L++ Sbjct 231 GPVVMIGLGIGPLRRLWPWSREVRDLETIHEFLGEEIEAARRDPALEERRDLMALLVRAS 290 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFL 300 T + L+DAELRDQL+TL+ AGHETTA A++W++ ELA P +Q + V G +L Sbjct 291 ATDAQGLSDAELRDQLMTLVAAGHETTATAMAWSMLELARHPRVQERCVAEIAGDGSEYL 350 Query 301 EAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRP 360 +AVLKE +R H V+ R++ PA IGG P G V+ SI+LAH S ++P P +F P Sbjct 351 DAVLKEVLRLHPVVPMVMRELQEPATIGGHTYPRGVTVSPSIVLAHRSPGTYPSPLDFDP 410 Query 361 SRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVR 420 RFL P WLPFGGG RRC+G FA+ EG VIL+++ R+ + G + E P R Sbjct 411 GRFLGEVPTPTEWLPFGGGARRCIGASFAMMEGEVILRQLLERYRLEPVGSGR-EWPRSR 469 Query 421 NITTVPKHGAHLRLIPQ 437 N+T P A + L P+ Sbjct 470 NVTLYPWRRARVDLRPR 486 >gi|120402053|ref|YP_951882.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119954871|gb|ABM11876.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=459 Score = 310 bits (793), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 173/432 (41%), Positives = 247/432 (58%), Gaps = 7/432 (1%) Query 7 TGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEI 66 T LPPGPRLPR +Q+ L LR F+ A R+YG F+LRV LV T P IK + Sbjct 20 TSLPPGPRLPRSVQAALMLRCGPRFVAACRRRYGSAFTLRVASMG-TLVYLTDPADIKTV 78 Query 67 FAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASV 126 FA DP HAGE N +L ++G+ SVL+ D H R L++ F R A+ +IA + Sbjct 79 FAGDPDIYHAGEANSMLKGLLGDTSVLVIDGDLHRDRRRLMLAPFARDAVAAQAGVIAEI 138 Query 127 AREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILA 186 A ++I W T M+ +TL++ILR V G +D A L + + +++++ P Sbjct 139 AADNIAGWPVGETFPVAPKMSEITLEVILRTVIGASDQARLAALRTVMPRVLSVGPWETL 198 Query 187 GVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKP 246 + L R PW+ + D +LY EIA RR D DL RTD L+ L++ D Sbjct 199 AIANQDLLRRRPWRAVRDAIAEADRLLYAEIADRRADPDLDTRTDALAMLVRAGD----- 253 Query 247 LTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLKE 306 ++D ELRDQLITLL+AGH+TTA ALSW L L P + ++ V AA GDD +L+AV KE Sbjct 254 MSDKELRDQLITLLVAGHDTTATALSWALERLTRHPAVLAKAVRAARDGDDDYLDAVAKE 313 Query 307 GMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDG 366 +R V+ R + AP E+ G+RLPAG +V ++ HA +P F P R L Sbjct 314 TLRDRPVVFDVGRVLKAPVELAGYRLPAGVMVIPGLVAVHADSQIYPHADRFDPDRMLGA 373 Query 367 SVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVP 426 +++P+++LPFGGG RRCLG FA+ E V+L+EI RR + ++GE ++++ VP Sbjct 374 TLSPSSYLPFGGGNRRCLGATFAMVEFKVVLREILRRVELETT-TARGEHRRLKHVIFVP 432 Query 427 KHGAHLRLIPQR 438 GA +R+ +R Sbjct 433 HRGARIRVRAKR 444 >gi|108797764|ref|YP_637961.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119866854|ref|YP_936806.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108768183|gb|ABG06905.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119692943|gb|ABL90016.1| cytochrome P450 [Mycobacterium sp. KMS] Length=447 Score = 302 bits (774), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 173/433 (40%), Positives = 249/433 (58%), Gaps = 8/433 (1%) Query 8 GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIF 67 LPPGPRLP +Q+VL +R F+ A R+YG VF+LR+ +V P IK +F Sbjct 11 ALPPGPRLPPSVQTVLLMRSWSRFVAACRRRYGPVFTLRISSIG-TMVYLADPADIKTVF 69 Query 68 AADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 A DPR HAGE N +L ++G+ SVL+ D+ H R L+M F R A+ +++A +A Sbjct 70 AGDPRVYHAGEANAMLRGLLGDTSVLVIDDDVHRDRRRLMMAPFHREAVARQVEVMAEIA 129 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 ++++RW M+ +TL++ILR V G +DP A L + + +++ + P Sbjct 130 ADNVSRWPVGEVFPVAPKMSEITLEVILRTVIGASDPARLAALRAIMPKLLQVTPWTTPA 189 Query 188 VPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPL 247 + P L+R+ W+ + D +LY EIA RR D +L RTDVL+ L+++ + + Sbjct 190 LANPGLQRLPLWRSLRERIEEADRLLYAEIAERRADPELRWRTDVLAMLVRSAGEDGRTM 249 Query 248 TDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAA---VGGD---DGFLE 301 TD ELRDQL+TLL+AGH+TTA LSW L L P + + V AA GD D +L+ Sbjct 250 TDRELRDQLMTLLVAGHDTTATGLSWALERLTRHPAVLTAAVRAADRSAAGDPSGDEYLD 309 Query 302 AVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPS 361 AV+KE +R V+ R +T P E+ G+RLPAG +V I L H +P+P F P Sbjct 310 AVVKEALRIRPVVFDVGRVLTEPTEVAGYRLPAGVMVVPGIGLVHDDPAVYPEPDRFDPD 369 Query 362 RFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRN 421 R L S+ P TWLPFGGG RRCLG FA+ E V+L+EI RR + + GE V++ Sbjct 370 RMLGASLTPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRAELCTTT-APGERRRVKH 428 Query 422 ITTVPKHGAHLRL 434 + VP GA +R+ Sbjct 429 VIMVPARGARVRV 441 >gi|315442488|ref|YP_004075367.1| cytochrome P450 [Mycobacterium sp. Spyr1] gi|315260791|gb|ADT97532.1| cytochrome P450 [Mycobacterium sp. Spyr1] Length=447 Score = 302 bits (774), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 179/449 (40%), Positives = 251/449 (56%), Gaps = 13/449 (2%) Query 5 LTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIK 64 +TTGLPPGPRLPR +Q+ L LR F+ A R+YG F+LRV LV T P IK Sbjct 2 VTTGLPPGPRLPRAVQAGLMLRLGPRFIDACKRRYGPTFTLRVAGMG-TLVYLTDPADIK 60 Query 65 EIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIA 124 +FA DPR HAGE N +L ++G+ SVL+ D H R +++ FTR A+ G ++A Sbjct 61 TVFAGDPRIYHAGEANSMLKGLLGDTSVLVVDGDAHRDRRRVMLAPFTRDAVAGQTGLMA 120 Query 125 SVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAI 184 +A ++I RW + M +TL+IILR V G +DP L + +++ + Sbjct 121 QIAADNIARWPVGRPFAAAPKMAQITLEIILRTVIGASDPARLTALREVMPRVLRVGAWE 180 Query 185 LAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPT 244 + +L +PW+ D +LY EIA RR D DL RTD LS L++T Sbjct 181 TLALANEALLGKSPWRTLREAIDAADGLLYAEIADRRADPDLVTRTDALSILVRTGG--- 237 Query 245 KPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVL 304 ++D ELRDQLITLL+AGH+TTA LSW L L+ PE+ ++ V AA G D +L+AV Sbjct 238 --MSDRELRDQLITLLVAGHDTTATGLSWALERLSRHPEVLARAVRAARTGQDDYLDAVA 295 Query 305 KEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFL 364 +E +R +V+ R + P ++GG+ LPAG + ++L H +P F P R L Sbjct 296 RETLRVRSVVFDVGRVLKEPVDLGGYTLPAGVMAIPGMVLVHGDPHIYPDADRFDPDRML 355 Query 365 DGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTI-TAAGPSKGETPLVRNIT 423 + P+T+LPFGGG RRCLG FA+ E V+L+EI RR + T P GE ++++ Sbjct 356 GVTPGPSTYLPFGGGNRRCLGATFAMVEFRVVLREILRRVDLQTTTAP--GERRRLKHVI 413 Query 424 TVPKHGAHLRLIPQR----RLGGLGDSDP 448 VP GA +R+ R R GG S P Sbjct 414 FVPHRGARIRVTATRSVPVRSGGDEGSCP 442 >gi|126433391|ref|YP_001069082.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126233191|gb|ABN96591.1| cytochrome P450 [Mycobacterium sp. JLS] Length=447 Score = 301 bits (770), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 172/433 (40%), Positives = 248/433 (58%), Gaps = 8/433 (1%) Query 8 GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIF 67 LPPGPRLP +Q+VL +R F+ A R+YG VF+LR+ +V P IK +F Sbjct 11 ALPPGPRLPPSVQTVLLMRSWSRFVAACRRRYGPVFTLRISSIG-TMVYLADPADIKTVF 69 Query 68 AADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 A DPR HAGE N +L ++G+ SVL+ D+ H R L+M F R A+ +++ +A Sbjct 70 AGDPRVYHAGEANAMLRGLLGDTSVLVIDDDVHRDRRRLMMAPFHREAVARQVEVMTEIA 129 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 ++++RW M+ +TL++ILR V G +DP A L + + +++ + P Sbjct 130 ADNVSRWPVGEVFPVAPKMSEITLEVILRTVIGASDPARLAALRAIMPKLLQVTPWTTPA 189 Query 188 VPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPL 247 + P L+R+ W+ + D +LY EIA RR D +L RTDVL+ L+++ + + Sbjct 190 LANPGLQRLPLWRSLRERIEEADRLLYAEIAERRADPELRWRTDVLAMLVRSAGEDGRTM 249 Query 248 TDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAA---VGGD---DGFLE 301 TD ELRDQL+TLL+AGH+TTA LSW L L P + + V AA GD D +L+ Sbjct 250 TDRELRDQLMTLLVAGHDTTATGLSWALERLTRHPAVLTAAVRAADRSAAGDPSGDEYLD 309 Query 302 AVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPS 361 AV+KE +R V+ R +T P E+ G+RLPAG +V I L H +P+P F P Sbjct 310 AVVKEALRIRPVVFDVGRVLTEPTEVAGYRLPAGVMVVPGIGLVHDDPAVYPEPDRFDPD 369 Query 362 RFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRN 421 R L S+ P TWLPFGGG RRCLG FA+ E V+L+EI RR + + GE V++ Sbjct 370 RMLGASLTPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRAELCTTT-APGERRRVKH 428 Query 422 ITTVPKHGAHLRL 434 + VP GA +R+ Sbjct 429 VIMVPARGARVRV 441 >gi|118467999|ref|YP_885605.1| cytochrome P450 monooxygenase [Mycobacterium smegmatis str. MC2 155] gi|118169286|gb|ABK70182.1| cytochrome P450 monooxygenase [Mycobacterium smegmatis str. MC2 155] Length=437 Score = 295 bits (756), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 167/417 (41%), Positives = 234/417 (57%), Gaps = 5/417 (1%) Query 19 LQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGE 78 +Q+ + LR F+ A R+YGDVF+LR+ V P IK +FA DP HAGE Sbjct 1 MQTAMMLRHWSRFVSACRRRYGDVFTLRIASMG-TWVYLADPADIKTVFAGDPTVFHAGE 59 Query 79 GNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHA 138 N +L ++GE SVL+ DE H R L++ F R A+ ++A VA +I W Sbjct 60 ANSMLSGLLGETSVLVIDEDVHRDRRRLMLAPFARDAVARQTGVMAEVAATNIASWPVGT 119 Query 139 TINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNP 198 M + L++ILR V G T+P A L + Q++ I P + P L+R P Sbjct 120 PFPVAPKMAEIALEVILRTVIGATEPARLAALRHVMPQLLGIGPWQSLAIASPGLQRRRP 179 Query 199 WKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLIT 258 W+ N + D +LY EIA+ R DL +R D L+ L++ + + +TD ELRDQL+T Sbjct 180 WRTLQRNLAEADRLLYAEIAACRAGPDLASRPDALAMLVRAANDEGRTMTDRELRDQLMT 239 Query 259 LLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAV---GGDDGFLEAVLKEGMRRHTVIA 315 LL+AGHETTA LSWTL L P + + V AA G + +L+AV++E +R V+ Sbjct 240 LLVAGHETTATGLSWTLERLIRHPAVLDKAVAAARTTDGSGEAYLDAVVRESLRIRPVVF 299 Query 316 STARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLP 375 R +T P E+GG+ LPAGT+V SI L HAS +P P F P R L + AP+TWLP Sbjct 300 EAGRVLTEPVELGGYLLPAGTLVAPSIGLVHASADVYPDPDRFEPDRMLASTQAPSTWLP 359 Query 376 FGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHGAHL 432 FGGG RRCLG FAL E V+L+EI R + A ++GE ++++T +P G + Sbjct 360 FGGGNRRCLGATFALVEMRVVLREILHRVDLFAT-TARGEKQRLKHVTMIPHRGGRI 415 >gi|340625595|ref|YP_004744047.1| putative cytochrome P450 135B1 CYP135B1 [Mycobacterium canettii CIPT 140010059] gi|340003785|emb|CCC42911.1| putative cytochrome P450 135B1 CYP135B1 [Mycobacterium canettii CIPT 140010059] Length=472 Score = 293 bits (750), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 177/440 (41%), Positives = 252/440 (58%), Gaps = 8/440 (1%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M+ T + GLPPGPRL +Q+VL LR FL A R+YG VF+L V + ++V + P Sbjct 1 MSGTSSMGLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFG-HMVYLSDP 59 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 IK +FA +PR HAGE N +L ++G+ S+L+ D+ H R L++P F R A+ Sbjct 60 AAIKTVFAGNPRVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMLPPFHRDAVARQA 119 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 ++A +A +I W M+ +TL++ILR V G +DP A L + +++N+ Sbjct 120 GLMAEIAAANIAGWPMAKQFAVAPKMSEITLEVILRTVIGASDPARLAALRKVMPRLLNV 179 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 P + PSL W R + D +LY EIA RR D DL ARTD L+ L++ Sbjct 180 GPWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAA 239 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD- 296 D + +T+ ELRDQLITLL+AGH+TTA LSW L L P ++ A+ GD Sbjct 240 DEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDP 299 Query 297 --DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPK 354 D +L+AV KE +R V+ R +T E+ G+RLPAG +V +I L HAS +P Sbjct 300 AGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASSQLYPD 359 Query 355 PTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKG 414 P F P R + +++P TWLPFGGG RRCLG FA+ E V+L+EI RR ++ S G Sbjct 360 PERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTS-G 418 Query 415 ETPLVRNITTVPKHGAHLRL 434 E P ++++ VP GA +R+ Sbjct 419 ERPKLKHVIMVPHRGARIRV 438 >gi|240169264|ref|ZP_04747923.1| cytochrome P450 135B4 Cyp135B4 [Mycobacterium kansasii ATCC 12478] Length=465 Score = 291 bits (746), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 177/439 (41%), Positives = 250/439 (57%), Gaps = 22/439 (5%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LP GPRLPR++Q++L L F+ A HR+YG VF+LRV +V P IK +FA Sbjct 11 LPRGPRLPRWVQALLMLTHGSHFVAACHRRYGGVFTLRVAGVG-TIVYLADPADIKTVFA 69 Query 69 ADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAR 128 DP HAGE N IL ++G+ S+L+ D+ H R +++P F R A+ ++A +A Sbjct 70 GDPSVFHAGEANSILRGLLGDGSLLVIDDDMHRDRRRMMLPPFHRDAVTRQARLMAEIAA 129 Query 129 EHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGV 188 E+I W M+ +TL++ILR V G +DP +RL + ++ P +L+ Sbjct 130 ENIATWPVGRDFAVAPKMSEITLEVILRTVVGASDP-------ARLAALRDVMPRLLSVG 182 Query 189 PYPSLKRMNPWKRFFHNQ-------TKIDEILYREIASRRIDSDLTARTDVLSRLLQTKD 241 P+ SL + P + D++LY EIA RR D DL RTD L+ L++ D Sbjct 183 PWDSLALVKPDLLRHRWWRRLRRRIVEADQLLYAEIADRRTDPDLATRTDALAMLVRAAD 242 Query 242 TPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD-- 296 T PLTD ELRDQL+TLL+AGH+TTA ALSW L L P + ++ A+ GD Sbjct 243 DDTGPLTDVELRDQLMTLLVAGHDTTATALSWVLERLTRHPAVLAKAVCAADASAAGDPA 302 Query 297 -DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKP 355 D +L+A+ KE +R +V+ R +T ++ G+RLPAGT+V I L H S +P+P Sbjct 303 GDEYLDALAKETLRIRSVVFDVGRVLTRAVDLAGYRLPAGTMVAPGIGLVHGSATLYPEP 362 Query 356 TEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGE 415 F P R L +++P TW PFGGG RRCLG FAL E VIL+EI RR +T S GE Sbjct 363 DRFDPDRMLGATLSPVTWFPFGGGNRRCLGATFALVEMRVILREILRRVELTTTTAS-GE 421 Query 416 TPLVRNITTVPKHGAHLRL 434 ++++ VP GA +R+ Sbjct 422 RQKLKHVIVVPHRGARIRV 440 >gi|183980959|ref|YP_001849250.1| cytochrome P450 135B4 Cyp135B4 [Mycobacterium marinum M] gi|183174285|gb|ACC39395.1| cytochrome P450 135B4 Cyp135B4 [Mycobacterium marinum M] Length=463 Score = 291 bits (744), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 179/441 (41%), Positives = 253/441 (58%), Gaps = 12/441 (2%) Query 4 TLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHI 63 T T LPPGPRLPR +Q+ L LR FL A R+YG VF+LRV +V T P I Sbjct 2 TKTATLPPGPRLPRAVQAALMLRHAPRFLTACKRRYGSVFTLRVAGLG-TMVNVTDPVVI 60 Query 64 KEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMI 123 K++FA DPR HAGE N +L ++GE S+L+ D+ H R +++P F R A+ ++ Sbjct 61 KKVFAGDPRVFHAGEANTMLAGLLGESSLLVVDDDVHRDRRRMMLPPFQREAVAHQAQLM 120 Query 124 ASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPA 183 + +A E+I W T M +TL++ILR V G TDP A L + +++N+ P Sbjct 121 SEIAAENIAGWPVGRTFAVAPKMAEITLEVILRTVIGATDPDRLAALRKVMPRLLNVGPW 180 Query 184 ILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKD-- 241 + P L W+R + +E+LY EIA RR D +L RTDVL+ L++ D Sbjct 181 ETLALAKPDLLSRRAWRRLRRAIDEANELLYAEIAERRADPNLAERTDVLATLVRAVDGD 240 Query 242 --TPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD 296 P+ +TD ELRDQL+TLL+AGH+TTA L+W L L P I ++ A+ GD Sbjct 241 TAKPSGRMTDEELRDQLMTLLVAGHDTTATGLAWALERLTRHPAILAKAVRAAEASAAGD 300 Query 297 ---DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHP 353 D +L+A+ KE +R V+ R +T P E+ G++LPAGT+V SI L HA+ +P Sbjct 301 PSGDEYLDALAKETLRIRPVVFDVGRILTEPTELAGYQLPAGTMVVASIGLVHANAEVYP 360 Query 354 KPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSK 413 P F P R +D ++ P TWLPFGGG RRCLG FA+ E V+L+EI RR + A + Sbjct 361 DPDRFDPDRMIDATLTPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVDL-ATTTAP 419 Query 414 GETPLVRNITTVPKHGAHLRL 434 E ++++ VP A +R+ Sbjct 420 DERYKLKHVILVPHRDARIRV 440 >gi|296168352|ref|ZP_06850276.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896783|gb|EFG76416.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=436 Score = 288 bits (737), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 164/423 (39%), Positives = 239/423 (57%), Gaps = 11/423 (2%) Query 19 LQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGE 78 +Q+ L L+ F+ A R+YG VF+LRV LV P +K +FA DPR HAGE Sbjct 1 MQAALMLQRGSHFVAACRRRYGSVFTLRVAGMG-TLVYLADPADVKTVFAGDPRVFHAGE 59 Query 79 GNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHA 138 N IL ++G+ S+L+ DE H R L++P F R A+ ++A +A +I W A Sbjct 60 ANSILSGLLGDTSLLVIDEDVHRDRRRLMLPPFHRDAVARQAGLMAEIAAANIATWPVGA 119 Query 139 TINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNP 198 + M +TL++ILR V G TDP A L + + +++++ P + P+L+R P Sbjct 120 NFAAAPKMAEITLEVILRTVIGATDPARLAALRAIMPRLLSVGPWATLALAKPALQRYRP 179 Query 199 WKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLIT 258 W+ + D +LY EIA RR D + RTDVL+ L++ D + ++D ELRDQL+T Sbjct 180 WRGLRRTMAEADRLLYAEIAERRADPGVAERTDVLAMLVRADDG-GRTMSDRELRDQLMT 238 Query 259 LLLAGHETTAAALSWTLWELAHAPEI------QSQVVWAAVGGDDGFLEAVLKEGMRRHT 312 LL+AGH+TTA LSW L L P++ ++ A D +L+A++KE +R Sbjct 239 LLVAGHDTTANGLSWALERLTRHPDVLARAVAAAEAGAAGDPAGDEYLDALVKETLRVRP 298 Query 313 VIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNT 372 V+ R +T PA++ G+RLPAG +V I L H S +P P F P R L +++P T Sbjct 299 VVFDVGRVLTEPADVAGYRLPAGVMVAPGIGLVHTSAAVYPDPHRFDPDRMLGATLSPTT 358 Query 373 WLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTI-TAAGPSKGETPLVRNITTVPKHGAH 431 W PF GG RRCLG GFA+ E V+L+EI RR + T A P+ E ++ + VP GA Sbjct 359 WFPFSGGNRRCLGAGFAMVEMRVVLREILRRVELDTTAAPA--ERQRLKFVVLVPHRGAR 416 Query 432 LRL 434 +RL Sbjct 417 IRL 419 >gi|121636486|ref|YP_976709.1| putative cytochrome p450 135b1 cyp135B1 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988958|ref|YP_002643645.1| putative cytochrome p450 135b1 [Mycobacterium bovis BCG str. Tokyo 172] gi|121492133|emb|CAL70598.1| Possible cytochrome p450 135b1 cyp135B1 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772071|dbj|BAH24877.1| putative cytochrome p450 135b1 [Mycobacterium bovis BCG str. Tokyo 172] gi|341600502|emb|CCC63172.1| possible cytochrome p450 135b1 cyp135B1 [Mycobacterium bovis BCG str. Moreau RDJ] Length=472 Score = 278 bits (712), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 177/440 (41%), Positives = 250/440 (57%), Gaps = 8/440 (1%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M+ T + GLPPGPRL +Q+VL LR FL A R+YG VF+L V + ++V + P Sbjct 1 MSGTSSMGLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFG-HMVYLSDP 59 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 IK +FA +P HAGE N +L ++G+ S+L+ D+ H R L+ P F R A+ Sbjct 60 AAIKTVFAGNPSVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMSPPFHRDAVARQA 119 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 + IA +A +I W M+ +TL++ILR V G +DP A L + +++N+ Sbjct 120 EPIAEIAAANIAGWPMAKAFAVAPKMSEITLEVILRTVIGASDPVRLAALRKVMPRLLNV 179 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 P + PSL W R + D +LY EIA RR D DL ARTD L+ L++ Sbjct 180 GPWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAA 239 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD- 296 D + +T+ ELRDQLITLL+AGH+TTA LSW L L P ++ A+ GD Sbjct 240 DEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDP 299 Query 297 --DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPK 354 D +L+AV KE +R V+ R +T E+ G+RLPAG +V +I L HAS +P Sbjct 300 AGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASAQLYPD 359 Query 355 PTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKG 414 P F P R + +++P TWLPFGGG RRCLG FA+ E V+L+EI RR ++ S G Sbjct 360 PERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTS-G 418 Query 415 ETPLVRNITTVPKHGAHLRL 434 E P ++++ VP GA +R+ Sbjct 419 ERPKLKHVIMVPHRGARIRV 438 >gi|15607708|ref|NP_215082.1| cytochrome P450 135B1 [Mycobacterium tuberculosis H37Rv] gi|15839966|ref|NP_335003.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|31791750|ref|NP_854243.1| cytochrome P450 135B1 [Mycobacterium bovis AF2122/97] 50 more sequence titles Length=472 Score = 277 bits (709), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 177/440 (41%), Positives = 249/440 (57%), Gaps = 8/440 (1%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M+ T + GLPPGPRL +Q+VL LR FL A R+YG VF+L V + ++V + P Sbjct 1 MSGTSSMGLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFG-HMVYLSDP 59 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 IK +FA +P HAGE N +L ++G+ S+L+ D+ H R L+ P F R A+ Sbjct 60 AAIKTVFAGNPSVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMSPPFHRDAVARQA 119 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 IA +A +I W M+ +TL++ILR V G +DP A L + +++N+ Sbjct 120 GPIAEIAAANIAGWPMAKAFAVAPKMSEITLEVILRTVIGASDPVRLAALRKVMPRLLNV 179 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 P + PSL W R + D +LY EIA RR D DL ARTD L+ L++ Sbjct 180 GPWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAA 239 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD- 296 D + +T+ ELRDQLITLL+AGH+TTA LSW L L P ++ A+ GD Sbjct 240 DEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDP 299 Query 297 --DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPK 354 D +L+AV KE +R V+ R +T E+ G+RLPAG +V +I L HAS +P Sbjct 300 AGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASAQLYPD 359 Query 355 PTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKG 414 P F P R + +++P TWLPFGGG RRCLG FA+ E V+L+EI RR ++ S G Sbjct 360 PERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTS-G 418 Query 415 ETPLVRNITTVPKHGAHLRL 434 E P ++++ VP GA +R+ Sbjct 419 ERPKLKHVIMVPHRGARIRV 438 >gi|289446115|ref|ZP_06435859.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis CPHL_A] gi|289419073|gb|EFD16274.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis CPHL_A] Length=472 Score = 275 bits (702), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 176/440 (40%), Positives = 248/440 (57%), Gaps = 8/440 (1%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M+ T + GLPPGPRL +Q+VL LR FL A R+YG VF+L V + ++V + P Sbjct 1 MSGTSSMGLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFG-HMVYLSDP 59 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 IK +FA +P HAGE N +L ++G+ S+L+ D+ H R L+ P F R A+ Sbjct 60 AAIKTVFAGNPSVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMSPPFHRDAVARQA 119 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 IA +A +I W M+ +TL++ILR V G +DP A L + +++N+ Sbjct 120 GPIAEIAAANIAGWPMAKAFAVAPKMSEITLEVILRTVIGASDPVRLAALRKVMPRLLNV 179 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 P + PSL W R + D +LY EIA RR D DL ARTD L+ ++ Sbjct 180 GPWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMRVRAA 239 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD- 296 D + +T+ ELRDQLITLL+AGH+TTA LSW L L P ++ A+ GD Sbjct 240 DEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDP 299 Query 297 --DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPK 354 D +L+AV KE +R V+ R +T E+ G+RLPAG +V +I L HAS +P Sbjct 300 AGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASAQLYPD 359 Query 355 PTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKG 414 P F P R + +++P TWLPFGGG RRCLG FA+ E V+L+EI RR ++ S G Sbjct 360 PERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTS-G 418 Query 415 ETPLVRNITTVPKHGAHLRL 434 E P ++++ VP GA +R+ Sbjct 419 ERPKLKHVIMVPHRGARIRV 438 >gi|169631766|ref|YP_001705415.1| cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169243733|emb|CAM64761.1| Probable cytochrome P450 [Mycobacterium abscessus] Length=467 Score = 274 bits (701), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 158/421 (38%), Positives = 234/421 (56%), Gaps = 10/421 (2%) Query 19 LQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGE 78 +QS+L + FL R+YG++F+LR+P + +V P IK ++A DP H+GE Sbjct 19 VQSILMASYGLRFLAGCQRRYGNMFTLRIP-LSGKVVYLADPADIKTVYAGDPHVFHSGE 77 Query 79 GNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHA 138 + ++G+ S+ + DE EH R LLMPAF R A+ +A +A +I W Sbjct 78 AHWFFRGLLGDSSLFVLDEDEHHHQRRLLMPAFHRDAVARQATQMAQIAAANIAEWPVGE 137 Query 139 TINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNP 198 + +TL++ILR V G +DP A L + +++ + P + P L+R P Sbjct 138 SFPVAPRTTDITLEVILRTVIGASDPVRLAALRKVVPRLLYMKPWETPAITNPGLRRYWP 197 Query 199 WKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLIT 258 W + D +LY EIA RR D +LT RTDVL+ L++ D + ++D ELRD L+T Sbjct 198 WTAVGRRMAETDALLYAEIAERRADPNLTERTDVLAMLVRATDDDGRTMSDQELRDHLLT 257 Query 259 LLLAGHETTAAALSWTLWELAHAPEI---QSQVVWAAVGGD---DGFLEAVLKEGMRRHT 312 + AGHETTA ALSW L L P+ +Q A+ GD D +L+AV+KE +R Sbjct 258 SIAAGHETTATALSWVLERLTRHPDALLKAAQAAEASAAGDPAGDEYLDAVVKETLRIRP 317 Query 313 VIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNT 372 VI S+ R + E+GG++LP G +V+ +I L HAS +P P F P R + +++P T Sbjct 318 VIFSSGRVLKESVEVGGYQLPVGIMVDPAIGLVHASGAVYPDPARFDPDRMVGTTLSPTT 377 Query 373 WLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTI-TAAGPSKGETPLVRNITTVPKHGAH 431 WLPFGGG RRCLG FA+ E V+L+EI RR + T P + + +++T VP G Sbjct 378 WLPFGGGNRRCLGATFAMVEIRVVLREILRRVELNTTTAPDEKQQ--AKHVTFVPHRGGS 435 Query 432 L 432 + Sbjct 436 I 436 >gi|183982980|ref|YP_001851271.1| cytochrome P450 135B6 Cyp135B6 [Mycobacterium marinum M] gi|183176306|gb|ACC41416.1| cytochrome P450 135B6 Cyp135B6 [Mycobacterium marinum M] Length=473 Score = 274 bits (701), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 165/434 (39%), Positives = 237/434 (55%), Gaps = 17/434 (3%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LPPGP L R LQ+ L L FL A R+YGDVF+LR+ V P IK +F Sbjct 9 LPPGPPLSRSLQAALMLLRGPQFLAACRRRYGDVFTLRIARMGTQ-VYLADPRDIKTVFT 67 Query 69 ADPRSLHAGEGNHILGFVMGEHSVLMTDEAEH-ARMRSLLMPAFTRAALRGYRDMIASVA 127 D HAG+ N +L ++G+ S+++ DE H R R++L P F R A+ ++A +A Sbjct 68 GDTHIFHAGDANALLSGLIGDSSLMVLDEEAHRCRRRTMLAP-FHRDAVARQAGLMAEIA 126 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 +++ W T M+ +TL++ILR V G TDP A L + + +++++ P Sbjct 127 ADNVAGWPAGRTFPVTVRMSEITLEVILRTVIGATDPARLAALRTAVPRLLSMGPWGTLA 186 Query 188 VPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPL 247 + P L PW+ +D +LY EI RR D++L R DVL+ L++T+ + Sbjct 187 LANPKLLSRRPWRGLRKRIADVDNLLYAEITDRRNDAELGKRADVLAMLIRTEGN-DNAM 245 Query 248 TDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ------VVWAAVGGDDGFLE 301 TD ELRDQL+TLL+AG++T+A L+W L L P I ++ A D +L+ Sbjct 246 TDRELRDQLVTLLVAGYDTSATGLAWALERLTRHPTILTRAVAAAHASAAGDAAGDEYLD 305 Query 302 AVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPS 361 AV+KE +R + + R + AP E+ G++LPAG I L HAS +P P F P Sbjct 306 AVVKETLRIRPLAFAVGRVLAAPVEVAGYQLPAGAWALPGIGLVHASAALYPDPDRFDPD 365 Query 362 RFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRR---FTITAAGPSKGETPL 418 R + S P TWLPFGGG RRCLG FAL E V+L+E+ RR T TAA ETP Sbjct 366 RMIGVSPGPTTWLPFGGGARRCLGATFALVEMRVVLREVLRRAELITTTAA----DETPK 421 Query 419 VRNITTVPKHGAHL 432 ++ +T +P GA + Sbjct 422 LKYVTLIPSRGARI 435 >gi|167968359|ref|ZP_02550636.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis H37Ra] gi|254549522|ref|ZP_05139969.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|294996078|ref|ZP_06801769.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis 210] gi|297633058|ref|ZP_06950838.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis KZN 4207] gi|297730035|ref|ZP_06959153.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis KZN R506] gi|313657363|ref|ZP_07814243.1| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis KZN V2475] Length=466 Score = 273 bits (699), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 175/433 (41%), Positives = 245/433 (57%), Gaps = 8/433 (1%) Query 8 GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIF 67 GLPPGPRL +Q+VL LR FL A R+YG VF+L V + ++V + P IK +F Sbjct 2 GLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFG-HMVYLSDPAAIKTVF 60 Query 68 AADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 A +P HAGE N +L ++G+ S+L+ D+ H R L+ P F R A+ IA +A Sbjct 61 AGNPSVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMSPPFHRDAVARQAGPIAEIA 120 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 +I W M+ +TL++ILR V G +DP A L + +++N+ P Sbjct 121 AANIAGWPMAKAFAVAPKMSEITLEVILRTVIGASDPVRLAALRKVMPRLLNVGPWATLA 180 Query 188 VPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPL 247 + PSL W R + D +LY EIA RR D DL ARTD L+ L++ D + + Sbjct 181 LANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAADEDGRTM 240 Query 248 TDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQ---VVWAAVGGD---DGFLE 301 T+ ELRDQLITLL+AGH+TTA LSW L L P ++ A+ GD D +L+ Sbjct 241 TERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDPAGDEYLD 300 Query 302 AVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPS 361 AV KE +R V+ R +T E+ G+RLPAG +V +I L HAS +P P F P Sbjct 301 AVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASAQLYPDPERFDPD 360 Query 362 RFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRN 421 R + +++P TWLPFGGG RRCLG FA+ E V+L+EI RR ++ S GE P +++ Sbjct 361 RMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTS-GERPKLKH 419 Query 422 ITTVPKHGAHLRL 434 + VP GA +R+ Sbjct 420 VIMVPHRGARIRV 432 >gi|183984453|ref|YP_001852744.1| cytochrome P450 135B3 Cyp135B3 [Mycobacterium marinum M] gi|183177779|gb|ACC42889.1| cytochrome P450 135B3 Cyp135B3 [Mycobacterium marinum M] Length=457 Score = 270 bits (690), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 162/438 (37%), Positives = 234/438 (54%), Gaps = 9/438 (2%) Query 1 MASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRP 60 M + T LPPGPRLPR +Q L +R FL A R+YGDVF+LRV +V P Sbjct 11 MIARTRTALPPGPRLPRSVQDALLIRHGPRFLAACRRRYGDVFTLRVASIG-TMVYVADP 69 Query 61 EHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYR 120 IK +FA DP +LH G + + G +G+ S+L+ D+ H R L++ F R + Sbjct 70 AVIKSVFAGDPNTLHGGAASMLRGL-LGDSSLLVVDDRAHRDRRRLMLAPFHRDVIERQA 128 Query 121 DMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI 180 +IA +A E++T W + M+ +TL++ILR V G +D A L + + +++++ Sbjct 129 GLIAEIAAENVTGWPVGTPFAAATKMSEITLEVILRTVIGTSDAARLAALRAVMPRLLDL 188 Query 181 HPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTK 240 P + P+L + PW+ + DE+LY EIA R D L+ R D L+ L+Q Sbjct 189 RPWETLALAKPNLLQRGPWRSLHRRIAEADELLYAEIAEHRTDPGLSGRADTLAMLIQAA 248 Query 241 DTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDG-- 298 + + D ELRDQL+TLL+AGH+ TAA L W L L P + ++ V AA G Sbjct 249 YDDGRTMADGELRDQLMTLLVAGHDNTAAGLCWALERLTRHPAVLAKAVQAADASAAGDP 308 Query 299 ----FLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPK 354 +L+AV+KE +R V+ R + P E+ G+ LP G +V SI L H S +P Sbjct 309 AGNEYLDAVVKETLRARPVVFDLGRVLRKPIELAGYLLPEGVMVVPSIGLVHGSAALYPG 368 Query 355 PTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKG 414 P F P R L + P WLPFGGG RRCLG FA+ E V+L+EI RR + + Sbjct 369 PERFDPDRMLGVILGPTGWLPFGGGSRRCLGAAFAMAEMRVVLREILRRVELCPT-TAVD 427 Query 415 ETPLVRNITTVPKHGAHL 432 E ++N+ VP G + Sbjct 428 ERQKLKNVILVPHRGGRI 445 >gi|296394390|ref|YP_003659274.1| cytochrome P450 [Segniliparus rotundus DSM 44985] gi|296181537|gb|ADG98443.1| cytochrome P450 [Segniliparus rotundus DSM 44985] Length=469 Score = 263 bits (673), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 169/435 (39%), Positives = 232/435 (54%), Gaps = 8/435 (1%) Query 11 PGPRLPRYLQSVLYLRFREW----FLPAMHRKYGDVFSLRVPPYADNLVVYTR-PEHIKE 65 PGPR P +Q+ L R W +L + K +V S R + + T P ++ Sbjct 11 PGPRWPAAVQTFLAFT-RGWEVGSWLRGHYAKTVEVRSYRRGSWVSIPTLLTSDPAMARQ 69 Query 66 IFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIAS 125 +FA P+ HAG N IL V+G+ S+L D +HAR+R LLMP+F AALRGY M Sbjct 70 VFAGSPKVYHAGASNAILAPVLGKRSLLSIDGEDHARIRKLLMPSFAGAALRGYASMFEE 129 Query 126 VAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAIL 185 +A +W +L+H + LTLDIILR VFGV+DP+ A L R+ ++ P Sbjct 130 LAEADAQQWPTGRVTAALEHTHRLTLDIILRTVFGVSDPQRSAVLRPRVLRVALPGPGTA 189 Query 186 AGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTK 245 P R+ + + N ++ IL EIA+RR DS + R DVLSR++ + + Sbjct 190 LWAWAPRSARLGVARGYRGNLAALNRILAEEIAARRADSAVHERKDVLSRMVAANEDGDR 249 Query 246 PLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLK 305 L D ELRDQL+TL++AG ETTA AL+W L +LAH P Q + AA GD L AV K Sbjct 250 -LCDEELRDQLLTLVMAGFETTAKALAWCLLDLAHNPAAQQRAQAAADEGDVEHLTAVFK 308 Query 306 EGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLD 365 E +R H V++ AR + +IG RL AG+ S H E P+P FRP RFLD Sbjct 309 ETLRLHPVVSGVARLLMETDQIGERRLAAGSRAAISFYPLHHDEELFPQPEAFRPERFLD 368 Query 366 GSVAP-NTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITT 424 + P + W PFGGGV RC+G F+ E A IL+ + R+T++ + NI Sbjct 369 QNQPPGHHWAPFGGGVYRCIGASFSQAEAAAILRSVLTRYTVSPMRAEMEPQSHMPNIVI 428 Query 425 VPKHGAHLRLIPQRR 439 PK G +RL + R Sbjct 429 GPKFGGQVRLARRER 443 >gi|284041673|ref|YP_003392013.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283945894|gb|ADB48638.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=462 Score = 259 bits (663), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 167/411 (41%), Positives = 238/411 (58%), Gaps = 11/411 (2%) Query 2 ASTLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPE 61 A+ T LPPGP PR L +L F+ +YG +F++R+ P +VV Sbjct 4 AAPDTRSLPPGPTGPRVLTVSRFLLQPTRFVGECRERYGRLFTIRLSP-GRTVVVAADAA 62 Query 62 HIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRD 121 KE+F DP LHAGEGN +L ++G SVL+ D EH R R L++P F +RGY + Sbjct 63 VAKEVFTGDPALLHAGEGNVVLRPLLGPRSVLLLDGPEHLRQRRLMLPPFHGERMRGYGE 122 Query 122 MIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI- 180 + ++A H+ +W M A+TL++ILRVVFGV +P A+L++ L+++++ Sbjct 123 RMRAIADRHVAQWPVGEPFAVQRSMQAITLEVILRVVFGVEEPARVAQLSAPLRRLLDST 182 Query 181 -HPAILAGVPY---PSLKRMNPWKRFFHNQTKIDEILYREIASRR--IDSDLTARTDVLS 234 P L + + PW R +D ++Y EIA+RR ++S R D+L+ Sbjct 183 EQPWRLLALQLTRSEGARPRTPWGRVRRLLAPVDAMIYEEIAARRAELESGRPTRDDILT 242 Query 235 RLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVG 294 LL +D +PLTDAELRD+L+TLLLAGHETTA AL+WTL + PE+ +++ A VG Sbjct 243 LLLSARDEDDQPLTDAELRDELMTLLLAGHETTATALTWTLERITRHPEVLARLE-AEVG 301 Query 295 GD--DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSH 352 G+ D +L+AV+KE +R V+ + RK+ AP GGW LPAG + +I L H + Sbjct 302 GEGADAYLDAVIKETLRLRPVVPAVVRKLQAPLTFGGWDLPAGVNIAPNIWLIHRDPALY 361 Query 353 PKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRR 403 P+P FRP RFLD + WLPFGGG+RRCLG FAL E ++L I R Sbjct 362 PEPEAFRPERFLDRTPGTYEWLPFGGGIRRCLGASFALYEMRMVLSTILER 412 >gi|284041826|ref|YP_003392166.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283946047|gb|ADB48791.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=460 Score = 252 bits (644), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 166/432 (39%), Positives = 226/432 (53%), Gaps = 7/432 (1%) Query 8 GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIF 67 GLPPGP LP LQ V + FL R++GD+F++RV + N+VV P IK F Sbjct 11 GLPPGPSLPTTLQDVALVTRLRPFLRRCQRRHGDLFTVRVHHFG-NIVVPADPALIKRTF 69 Query 68 AADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 A P +LH+GEG+ LG V+G +S+L+TDE H R R LL+P F ++ Y +I +V Sbjct 70 TASPVALHSGEGSP-LGPVLGPNSLLVTDEDVHLRQRKLLLPPFHGQRMQRYEQLIEAVT 128 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 RE I RW +TL IL VFG ++ +L L + + A LA Sbjct 129 REEIARWPRDREFPVAPSTMRITLRAILLAVFGARGDALR-QLEELLPPLTTLGSA-LAL 186 Query 188 VPY--PSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTK 245 PY L +PW RF + ++D + +A R D DL R+DVL+ L+Q Sbjct 187 TPYLQHDLGPRSPWGRFKRLRAQVDAVCDELMAQARRDPDLAERSDVLALLVQATYEDGA 246 Query 246 PLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLK 305 P+ DAE+RDQL+T+L AGHETTAA L+WT+ L P++ ++V A G +A ++ Sbjct 247 PMRDAEIRDQLMTMLAAGHETTAAQLAWTVERLRRHPDVLERLVAEADAGGRELRDATIR 306 Query 306 EGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLD 365 E R+ VI T R V P E+GG+ LP GT + + L H E P F P RFL Sbjct 307 EVQRQRPVIMFTTRLVKEPFELGGFMLPPGTRIALAGALTHYDERLFADPFAFSPERFLG 366 Query 366 GSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTV 425 WLPFGGGVRRC+G FA E V+L+ I + + A S E R I Sbjct 367 RKPETYAWLPFGGGVRRCIGAAFAHMEMDVVLRTILLTYAL-APTSSPPERMKFRGIAHT 425 Query 426 PKHGAHLRLIPQ 437 P G R+ P+ Sbjct 426 PASGGLARVTPR 437 >gi|308372935|ref|ZP_07430431.2| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis SUMu005] gi|308374046|ref|ZP_07434618.2| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis SUMu006] gi|308375198|ref|ZP_07443052.2| cytochrome P450 135B1 cyp135B1 [Mycobacterium tuberculosis SUMu007] 12 more sequence titles Length=449 Score = 252 bits (643), Expect = 9e-65, Method: Compositional matrix adjust. Identities = 163/414 (40%), Positives = 231/414 (56%), Gaps = 8/414 (1%) Query 31 FLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGEGNHILGFVMGEH 90 FL A R+YG VF+L V + ++V + P IK +FA +P HAGE N +L ++G+ Sbjct 8 FLTACQRRYGSVFTLHVAGFG-HMVYLSDPAAIKTVFAGNPSVFHAGEANSMLAGLLGDS 66 Query 91 SVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHATINSLDHMNALT 150 S+L+ D+ H R L+ P F R A+ IA +A +I W M+ +T Sbjct 67 SLLLIDDDVHRDRRRLMSPPFHRDAVARQAGPIAEIAAANIAGWPMAKAFAVAPKMSEIT 126 Query 151 LDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNPWKRFFHNQTKID 210 L++ILR V G +DP A L + +++N+ P + PSL W R + D Sbjct 127 LEVILRTVIGASDPVRLAALRKVMPRLLNVGPWATLALANPSLLNNRLWSRLRRRIEEAD 186 Query 211 EILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAA 270 +LY EIA RR D DL ARTD L+ L++ D + +T+ ELRDQLITLL+AGH+TTA Sbjct 187 ALLYAEIADRRADPDLAARTDTLAMLVRAADEDGRTMTERELRDQLITLLVAGHDTTATG 246 Query 271 LSWTLWELAHAPEIQSQ---VVWAAVGGD---DGFLEAVLKEGMRRHTVIASTARKVTAP 324 LSW L L P ++ A+ GD D +L+AV KE +R V+ R +T Sbjct 247 LSWALERLTRHPVTLAKAVQAADASAAGDPAGDEYLDAVAKETLRIRPVVYDVGRVLTEA 306 Query 325 AEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCL 384 E+ G+RLPAG +V +I L HAS +P P F P R + +++P TWLPFGGG RRCL Sbjct 307 VEVAGYRLPAGVMVVPAIGLVHASAQLYPDPERFDPDRMVGATLSPTTWLPFGGGNRRCL 366 Query 385 GFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHGAHLRLIPQR 438 G FA+ E V+L+EI RR ++ S GE P ++++ VP GA +R+ R Sbjct 367 GATFAMVEMRVVLREILRRVELSTTTTS-GERPKLKHVIMVPHRGARIRVRATR 419 >gi|254823430|ref|ZP_05228431.1| cytochrome P450 family protein [Mycobacterium intracellulare ATCC 13950] Length=404 Score = 251 bits (642), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 151/398 (38%), Positives = 223/398 (57%), Gaps = 12/398 (3%) Query 38 KYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDE 97 +YGD F++++ +V+ + P+ +++IF + P + AGE N IL V+G++SVL+ D Sbjct 7 RYGDTFTMKLVGEG-PIVMVSHPDAVRQIFTSPPELMLAGEANRILQPVVGQNSVLLLDR 65 Query 98 AEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHATINSLDHMNALTLDIILRV 157 H R LLMPAF L+ Y + ++A+ I RW + M ALTL++IL + Sbjct 66 DAHREQRRLLMPAFRGNQLQSYMSTMTAIAQAEIARWPRGVPVRLHPRMQALTLEVILHL 125 Query 158 VFGVTDPKVKAELTSRLQQIINIHPAILAGVPYPSLKRMNPWKR---FFHNQ-TKIDEIL 213 VFG+ + L LQ+ + + G L + P K H +D +L Sbjct 126 VFGLERGQSMDRLRQALQRTLVL---TTNGAAQFFLLLVGPRKMRTALIHKLLADVDRLL 182 Query 214 YREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSW 273 + EIA+ R +DL RTDVLS LL+ + P++D E+RD+LITLLLAGHETTA+ L+W Sbjct 183 HEEIATPRRQADLDTRTDVLSMLLKARHEDGNPMSDQEIRDELITLLLAGHETTASGLAW 242 Query 274 TLWELAHAPEIQSQVVWAAVGGDDG--FLEAVLKEGMRRHTVIASTARKVTAPAEIGGWR 331 + + P+ S+++ A DDG +++AV+KE +R V+A +R++T P E+ G+ Sbjct 243 AVERIIRHPDAHSRLIEEA-HADDGQRYVDAVVKETLRMRPVLALVSRRLTEPMEVDGFS 301 Query 332 LPAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALT 391 LPAG V SI L H +P P +FRP RFLD TW+PFGGGVRRCLG FA Sbjct 302 LPAGVKVAPSIYLMHRRPDIYPDPKQFRPERFLDNRAGTYTWIPFGGGVRRCLGATFAEC 361 Query 392 EGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHG 429 E ++L +F + +K E R+IT VP G Sbjct 362 EMRIVLGAMFTTMRVRPVD-AKSEPIHRRSITQVPGRG 398 >gi|256377230|ref|YP_003100890.1| cytochrome P450 [Actinosynnema mirum DSM 43827] gi|255921533|gb|ACU37044.1| cytochrome P450 [Actinosynnema mirum DSM 43827] Length=444 Score = 246 bits (628), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 158/405 (40%), Positives = 224/405 (56%), Gaps = 15/405 (3%) Query 38 KYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDE 97 KYGDV +L + P+ + +Y P H++ + + P H GEGN L VMGEHS+L D Sbjct 43 KYGDVVALDIWPWRAVVFLYD-PAHVQAMTGSPPSRFHGGEGNLPLKPVMGEHSLLSVDG 101 Query 98 AEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHATINSLDHMNALTLDIILRV 157 EH R R+LL P FT+ A+RGYRD + +A I W + S + L L +I RV Sbjct 102 DEHRRARALLSPLFTKPAVRGYRDAVRELAEHEIATWPVGSPFPSYPRVRRLALRVISRV 161 Query 158 VFGV-TDPKVKAELTSRLQQIINIHPA----ILAGVPYPSLKRMNPWKRFFHNQTKIDEI 212 V G DP++ RL+++ ++ PA +L G+P P L+R W+R ++D + Sbjct 162 VLGADDDPRLP-----RLRELFDVLPAVDIPVLLGLPSPVLRRWGRWRRAALTLGRLDAL 216 Query 213 LYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALS 272 ++ A RR D L RTD+LSRLL L+ ELRD ++TL++AG+ETTA+ L+ Sbjct 217 VHAITADRRADPRLAERTDLLSRLLVAAG--PGALSPPELRDHVVTLVVAGYETTASTLA 274 Query 273 WTLWELAHAPEIQSQVVWAAVGGDDGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRL 332 W L ELA P AA GD G+LEAV+KE +RRH I+ +T E+ G+RL Sbjct 275 WALHELARHPAAARTAALAAASGDTGYLEAVVKETLRRHPPISELPWTLTEDVELAGYRL 334 Query 333 PAGTVVNTSILLAHASEVSHPKPTEFRPSRFLD-GSVAPNTWLPFGGGVRRCLGFGFALT 391 G + I + H H P FRP RFL+ G+V +TW+PFG GVRRC+G A+ Sbjct 335 TRGATLMPVIGVVHNDPAHHRDPRAFRPERFLEQGAVPAHTWMPFGNGVRRCVGANLAVL 394 Query 392 EGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHGAHLRLIP 436 E +L+ + R +TA + E P R +T+ P GA + L P Sbjct 395 EAVEVLRVLLARHALTADR-RRPERPASRLVTSAPARGARIVLTP 438 >gi|254416685|ref|ZP_05030435.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] gi|196176425|gb|EDX71439.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] Length=457 Score = 246 bits (628), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 152/451 (34%), Positives = 248/451 (55%), Gaps = 31/451 (6%) Query 12 GPRLPRYLQ--SVLYLRFREW-FLPAMHRKYGDVFSL---RVPPYADNLVVYTRPEHIKE 65 GPR PR+L+ ++ L FR +L ++YGD+ + PP+ V + P+ IKE Sbjct 6 GPRTPRFLRIFRIIKLIFRPLDYLENYAQRYGDMIKIGGDNAPPF----VYVSNPQAIKE 61 Query 66 IFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIAS 125 IF ADP +G GN +L +++G++S+LM D H R R LLMP F LR Y +I Sbjct 62 IFTADPELFESGRGNGVLRYLVGDNSLLMLDGEPHQRQRRLLMPPFHGDRLREYGQLICD 121 Query 126 VAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAIL 185 + W + + +TL +IL+ VFG+ + +L L ++ + L Sbjct 122 ITETVTAEWTVGQPLLIRTYTQEITLRVILQAVFGLNQGERYTQLRHLLSTLLAAFDSPL 181 Query 186 AG--VPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQT 239 + + +P L++ +PW RF + +I ++++ EI RR D +RTD+L+ LL Sbjct 182 SSTLLFFPWLRQDWGAWSPWGRFLQLKQQIKQLIFDEIRERREQGD-ESRTDILTLLLSA 240 Query 240 KDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGD-DG 298 +D P+TD EL DQL+TLL+AGHETTA+AL W L+ + + P+++ +++ D +G Sbjct 241 RDEAGDPMTDEELHDQLMTLLIAGHETTASALVWALYWIHYLPDVRQKLLEELETLDAEG 300 Query 299 ---------FLEAVLKEGMRRHTVIASTARKV-TAPAEIGGWRLPAGTVVNTSILLAHAS 348 +L AV +E +R + + ST ++ +P EI G++ AGT + SI L H Sbjct 301 DPMAISRLPYLTAVCQETLRIYPIAPSTFIRIPKSPIEIMGYQFEAGTALMPSIYLVHHR 360 Query 349 EVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITA 408 + +P+P +F+P RFL+ +P +LPFGGG RRC+G AL E ++L I +F + A Sbjct 361 DDIYPQPKQFKPERFLERQYSPYEYLPFGGGNRRCIGSALALLEMKLVLATILSQFEL-A 419 Query 409 AGPSKGETPLVRNITTVPKHGAHLRLIPQRR 439 ++ P+ R +T P +LR++P++R Sbjct 420 LTDNRPVKPMRRGLTIAPP--GNLRMVPKQR 448 >gi|186683024|ref|YP_001866220.1| cytochrome P450 [Nostoc punctiforme PCC 73102] gi|186465476|gb|ACC81277.1| cytochrome P450 [Nostoc punctiforme PCC 73102] Length=488 Score = 246 bits (627), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 138/451 (31%), Positives = 241/451 (54%), Gaps = 19/451 (4%) Query 4 TLTTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHI 63 T T LP GP++PR+L+++ ++ ++ + YGD F++R +++V +++P+ + Sbjct 30 TATYNLPDGPQMPRWLRTIKFISQPVKYVDDFAKTYGDTFTIRSSRSDNHIVYFSQPQAL 89 Query 64 KEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMI 123 +EIF AD R G GN L F++G+ S ++ D H R R LL P F +R Y + I Sbjct 90 EEIFTADSRHFEVGRGNTGLRFLLGDRSFMLVDGDRHQRQRQLLAPPFHGERMRAYGEDI 149 Query 124 ASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI--H 181 + ++ W+ N + M +TL +ILRVVFG+ + ++ EL L +++ Sbjct 150 RKITQQVSHEWKIGKPFNIRESMQEITLRVILRVVFGLNEGELFEELRRSLSDLLDFISS 209 Query 182 PAILAGVPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLL 237 P + + + +++ +PW R + K+D ++Y + RR +D R D+LS ++ Sbjct 210 PIMSSAFFFRFIQKDFGAWSPWGRILLQRQKVDLLIYTLLRERRAQTD-QNRQDILSLMM 268 Query 238 QTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWA--AVGG 295 + + ++D EL D+L+TLL+AGHETTA+AL+W + + H PE++ +++ +G Sbjct 269 AARYDDGQGMSDEELHDELMTLLVAGHETTASALTWAFYWIDHLPEVREKLLQELNTIGV 328 Query 296 DDG--------FLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAH 346 + +L AV +E +R + + + + R V P I G+ L GT + SI LAH Sbjct 329 NPDLSSVAKLPYLTAVCQETLRIYPIAMTAFVRIVKTPITIMGYELREGTAIVPSIYLAH 388 Query 347 ASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTI 406 E +P+ +F+P RFL+ +P +LPFGGG RRC+G FA E ++L + F + Sbjct 389 HREEVYPQSKQFKPERFLERQYSPYEYLPFGGGNRRCIGMAFAQYEMKIVLATVLSEFQV 448 Query 407 TAAGPSKGETPLVRNITTVPKHGAHLRLIPQ 437 + + P+ R +T G + PQ Sbjct 449 SLVN-KRPVHPVRRGLTVATPAGMRMVATPQ 478 >gi|186684527|ref|YP_001867723.1| cytochrome P450 [Nostoc punctiforme PCC 73102] gi|186466979|gb|ACC82780.1| cytochrome P450 [Nostoc punctiforme PCC 73102] Length=464 Score = 245 bits (626), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 139/441 (32%), Positives = 242/441 (55%), Gaps = 19/441 (4%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LP GP+ ++Q +L ++ A ++YGD+F+L++ + V + P+ I++IF Sbjct 6 LPNGPQTHPWIQMYQWLTNPLEYMEACTKRYGDIFTLKLGQNFAHQVFISNPQAIQQIFT 65 Query 69 ADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAR 128 DP+ L +GE I ++G+ S+L D H R R LL P F + Y ++I + Sbjct 66 TDPKQLDSGESAGIKAPLLGQQSLLALDGKPHQRQRKLLTPPFHGERMLAYGELIREITE 125 Query 129 EHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAGV 188 + ++W+ T L M A++ +IL+ VFG+ D +L L +I+N +L V Sbjct 126 QVSSQWQVGETFAVLPSMQAISFQVILKAVFGLEDGPRYKKLNELLIKILNPKIPLLRTV 185 Query 189 --PYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDT 242 +PS+++ +PW ++ + +ID+++Y +I R+ +L+ TD+LS ++ +D Sbjct 186 LLIFPSMRQDLGAWSPWGKYLRLRQQIDQLIYAQIQERKAQPNLSG-TDILSLMMAARDE 244 Query 243 PTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDG---- 298 +P+TD ELRD+L+TLL+AGHETTA +LSW L+ + H P+++ +++ + Sbjct 245 AGEPMTDLELRDELMTLLVAGHETTATSLSWALYWIHHRPQVREKLLQELDNLGEKPDPN 304 Query 299 ------FLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVS 351 +L AV E +R + V +++ R V +P +IG + GT++ SI L H E Sbjct 305 AIFRLPYLNAVCSETLRLYPVAMSALNRLVKSPLQIGEYNFEPGTILIPSIYLTHHREDL 364 Query 352 HPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGP 411 +P+ +F+P RFL+ +P +LPFGGG RRC+G FAL E ++L + R+ + A Sbjct 365 YPESKQFKPERFLERQFSPYEYLPFGGGNRRCIGMAFALFEMKLVLATVLSRWQMELAD- 423 Query 412 SKGETPLVRNITTVPKHGAHL 432 SK P+ + + P G + Sbjct 424 SKPVRPVRKGLLFSPAGGVQM 444 >gi|342860591|ref|ZP_08717242.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342132246|gb|EGT85487.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=404 Score = 245 bits (626), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 149/399 (38%), Positives = 220/399 (56%), Gaps = 14/399 (3%) Query 38 KYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDE 97 +YGD F++++ +V+ + P+ +++IF A P AGE N IL V+G +SVL+ D Sbjct 7 RYGDTFTMKLL-REGPIVMVSHPDAVRQIFTASPELALAGEANRILLPVVGRNSVLLLDR 65 Query 98 AEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWRPHATINSLDHMNALTLDIILRV 157 H R LLMPAF L+ Y + ++ + W I M ALTL++IL + Sbjct 66 DAHKEQRRLLMPAFRGNHLQNYMSTMTAIVEAEMAGWPRGVPIRLHPRMQALTLEVILHL 125 Query 158 VFGVTDPKVKAELTSRLQQIINIHPAILAG----VPYPSLKRMNPWKRFFHNQTKIDEIL 213 VFG+ + L LQ+++ + +A V P R RF ++D +L Sbjct 126 VFGLERGEKMDRLRQALQRMLALTTHAVAQMFLLVLGPQKLRTALTNRFL---AEVDRLL 182 Query 214 YREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSW 273 + EI +RR +DL RTDVLS LL+ + P++D E+RD+L+TLLLAGHETTA+ L+W Sbjct 183 HDEITTRRRQADLDDRTDVLSMLLKAEHEDGNPMSDKEIRDELVTLLLAGHETTASGLAW 242 Query 274 TLWELAHAPEIQSQVVWAAVGGD-DGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRL 332 + + P++ S+++ GD +++AV+KE +R V+A +R++T P E+ G+ L Sbjct 243 AVERIIRHPDVHSRLIAETHSGDGQSYVDAVVKETLRMRPVLALVSRRLTEPMELDGFSL 302 Query 333 PAGTVVNTSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTE 392 PAG V SI L H +P P FRP RFL+ TW+PFGGGVRRCLG FA E Sbjct 303 PAGVKVAPSIYLMHRRPDVYPDPERFRPERFLENRAGTYTWIPFGGGVRRCLGATFAECE 362 Query 393 GAVILQEIFRRFTITAAGP--SKGETPLVRNITTVPKHG 429 ++L + F+ T P K E R+IT VP G Sbjct 363 MRIVLGAL---FSTTRVRPVDVKSEPIHRRSITHVPGRG 398 >gi|119512554|ref|ZP_01631632.1| Cytochrome P450 [Nodularia spumigena CCY9414] gi|119462815|gb|EAW43774.1| Cytochrome P450 [Nodularia spumigena CCY9414] Length=453 Score = 244 bits (624), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 141/450 (32%), Positives = 245/450 (55%), Gaps = 19/450 (4%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LP GP+ +LQ+ +L ++ + YGD+F++RV P + V + P+ I++IF+ Sbjct 6 LPDGPKNHPWLQTYRWLTSPLEYMEDCAKNYGDIFTIRVGPLSTPQVFVSNPQAIQQIFS 65 Query 69 ADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAR 128 DP+ L +G ++G S+L D H R R LL P F + Y ++I +++ Sbjct 66 TDPKYLDSGAAAGFKSPLLGNQSLLSLDGKPHQRQRKLLTPPFHGERMLAYGELIRDISQ 125 Query 129 EHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG- 187 + +W+ T++ L M A++ +IL+ VFG+ + ++ L I+N +L Sbjct 126 QVTNKWQVGETVSVLSSMQAISFQVILKAVFGLAEGPRYEKIKEALIAILNPKKPLLRSM 185 Query 188 -VPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDT 242 + +PSL+R +PW F + +IDE++Y EI R+ D ++RTD+LS ++ T+D Sbjct 186 LLMFPSLRRDLGAWSPWGEFLRLRQQIDELVYAEIQERKAQLD-SSRTDILSLMMATRDE 244 Query 243 PTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWA--AVGGDDG-- 298 +P+TD ELRD+L+TLL+AGHETTA ALSW L+ + H P+++ +++ +G Sbjct 245 AGEPMTDLELRDELMTLLVAGHETTATALSWALYWIHHQPQVREKLLQELDTLGEKPDPN 304 Query 299 ------FLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVS 351 +L AV E +R + V + +R V +P +IG ++ GT++ + L H E Sbjct 305 AIFRLPYLNAVCSETLRLYPVAMLLLSRLVKSPLQIGEYQFEPGTLLIPCVYLTHHREDL 364 Query 352 HPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGP 411 +P F+P RFL+ + + ++PFGGG RRC+G FAL E ++L + + + A Sbjct 365 YPDSQTFKPERFLERQFSNSEFIPFGGGNRRCIGMAFALFEMKLVLATVLSNWQMELAN- 423 Query 412 SKGETPLVRNITTVPKHGAHLRLIPQRRLG 441 ++ P+ + + PK G + + +R L Sbjct 424 TQPVLPVRKGLLFGPKGGVQMVVKGRRELS 453 >gi|307153475|ref|YP_003888859.1| cytochrome P450 [Cyanothece sp. PCC 7822] gi|306983703|gb|ADN15584.1| cytochrome P450 [Cyanothece sp. PCC 7822] Length=457 Score = 241 bits (615), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 145/460 (32%), Positives = 243/460 (53%), Gaps = 27/460 (5%) Query 1 MASTLTT----GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVV 56 M S ++T LP GP++P +Q++L L + L ++KYGD+F V Sbjct 1 MTSVISTQAAAKLPDGPKIPAIIQTILALMDQFGSLERNYQKYGDIFYTPKSSLFPAFVA 60 Query 57 YTRPEHIKEIFAADPRSLHAGEGNHI-LGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAA 115 + P+ ++++ A+PR G+ + + + ++G++S+++ D EH + R LLMP F Sbjct 61 LSDPKAVEKVLTANPRLFEVGKQSSLAVRVLLGDNSLVLLDGIEHQKRRKLLMPPFHGER 120 Query 116 LRGYRDMIASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQ 175 ++ Y I V +E + +W+ + + D+ ++L +ILR VFG+ + + A L L Sbjct 121 MKSYGQTIVDVTKEVMAQWQEGKSFSIRDYTQQISLRVILRTVFGLDEGERYARLEKILT 180 Query 176 QIINIH--PAILAGVPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTAR 229 +NI P + +P L++ PW +F + I EIL EI RR + D + Sbjct 181 AWLNIFNSPFNAFFLFFPVLQKDFGAWTPWGQFVEQKRLIHEILQSEIERRRHNPD-SLG 239 Query 230 TDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVV 289 D+LS LL +D +P++D E++D+L+T+L AGHETTA L+W + + + PEI +++ Sbjct 240 EDILSLLLSVEDEEGQPMSDTEIKDELMTMLFAGHETTANTLAWAFYWIHYRPEIYQKLL 299 Query 290 WAAVGGDDG----------FLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVN 339 D+ +L AV+ E +R + V+ +R++ P EI G++ AGT + Sbjct 300 AELNSLDENADFNAINKLPYLNAVVSETLRLYPVVPFLSRQLKEPFEIMGYQFEAGTALL 359 Query 340 TSILLAHASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQE 399 I L H E +P+P +F+P RFL+ +P +LPFGGG RRCLG+ FAL E ++L Sbjct 360 PCIYLIHQREDIYPQPKQFKPERFLEKQFSPYEYLPFGGGHRRCLGYAFALFEMKLVLAT 419 Query 400 IFRR--FTITAAGPSKGETPLVRNITTVPKHGAHLRLIPQ 437 + + + P K + R IT P G +RL Q Sbjct 420 VLSQVHLELPFQRPPKA---IRRGITFAPSGGLKMRLKKQ 456 >gi|17231238|ref|NP_487786.1| cytochrome P450 [Nostoc sp. PCC 7120] gi|17132880|dbj|BAB75445.1| cytochrome P450 [Nostoc sp. PCC 7120] Length=462 Score = 240 bits (613), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 148/450 (33%), Positives = 239/450 (54%), Gaps = 19/450 (4%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LP GP+ P ++Q + ++ FL ++YGD+FS+++ +V + P+ I++I Sbjct 3 LPKGPQTPVFVQVLRWVFSPMSFLEDCAKRYGDIFSVKLAKDVPAIVFLSNPKDIQQILT 62 Query 69 ADPRSLHA-GEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 D L + G+ N + ++G+ SV+ AEH R R LLMP F +RGY +I V Sbjct 63 NDNNQLDSPGDWNDLFEPLLGKRSVITLSGAEHQRQRQLLMPPFHGERMRGYSQVITDVT 122 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQII--NIHPAIL 185 + I++ + A+TL +I++ VFG+ + +L L ++ + P + Sbjct 123 EKVISQHQIGQPFQVRSVTQAITLRVIMQAVFGLYEGSRAEKLQHLLSDLLEKSSSPFSV 182 Query 186 AGVPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKD 241 A + +PSL+R + W Q + DE++Y+EI RR + D +RTD+LS L+ +D Sbjct 183 ALLYFPSLRRDFGPIKFWGEQVQIQQQADELIYQEIQERRENPD-PSRTDILSLLMDARD 241 Query 242 TPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDG--- 298 +P+TD ELRD+L+TLL+AGHETTA AL+W ++ + P ++++++ D Sbjct 242 ADGQPMTDVELRDELMTLLVAGHETTATALAWAMYWIHKLPPVKARLLEELDSLGDNPDS 301 Query 299 -------FLEAVLKEGMRRHTVIAST-ARKVTAPAEIGGWRLPAGTVVNTSILLAHASEV 350 +L AV E +R + V T AR+V +GG+ LP GT V SI L H E Sbjct 302 TTIFKLPYLNAVYSETLRIYPVAMLTFARRVIETMALGGYELPPGTPVLGSIYLTHHRED 361 Query 351 SHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAG 410 +P+P +F+P RFL+ +P +LPFGGG RRCLG FA E + L +I + + Sbjct 362 LYPEPKKFKPERFLERQFSPYEYLPFGGGTRRCLGLAFAQWEMKLALAKILTSYELELVN 421 Query 411 PSKGETPLVRNITTVPKHGAHLRLIPQRRL 440 S P R + T P + + QR++ Sbjct 422 NSVEVRPKRRGLVTGPHRPIEMVIKSQRQI 451 >gi|158334010|ref|YP_001515182.1| cytochrome P450 family protein [Acaryochloris marina MBIC11017] gi|158304251|gb|ABW25868.1| cytochrome P450 family [Acaryochloris marina MBIC11017] Length=454 Score = 240 bits (612), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 147/451 (33%), Positives = 241/451 (54%), Gaps = 23/451 (5%) Query 6 TTGLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKE 65 T LP GP Q + ++ F+ A ++YGD+F+L++ +V + P I+E Sbjct 10 THKLPEGPSSSGLWQMLQWIGRPLGFMEACRQRYGDLFTLQLGQLG-QIVFCSNPVGIEE 68 Query 66 IFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIAS 125 I ADP+ + AG N +L ++G SV++ D H R R LLMP F +R Y I Sbjct 69 ILTADPKKMDAGCNNSVLLPLLGNASVILLDGESHQRQRQLLMPPFHGERMRAYGSSITQ 128 Query 126 VAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINI--HPA 183 + ++ + W+ + + + M A++L++I++ VFGV++P+ L + L Q +++ PA Sbjct 129 ITKDIASPWQVNHPFDVREAMQAISLNVIVKTVFGVSNPERYQALQALLPQFLDLTGSPA 188 Query 184 ILAGVPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQT 239 + + L++ +PW RF ++++D +LY+++ R S++ +D+LS +L Sbjct 189 GASLLFLRGLQKDWGAWSPWGRFLRVRSQLDHLLYQQMDEHRSQSEMG--SDILSLMLAA 246 Query 240 KDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDG- 298 D P+TD ELRD+L+TLLLAGHETTA+AL+W L+ + P+++ +++ D Sbjct 247 TDEVGNPMTDIELRDELVTLLLAGHETTASALTWALYWIHFLPDVKEKLIAELATADLND 306 Query 299 --------FLEAVLKEGMRRHTVIASTARKVT-APAEIGGWRLPAGTVVNTSILLAHASE 349 +L AV E +R + + T+ + T P + G LP GT V I L H S Sbjct 307 AKSIQRLPYLNAVCSETLRIYPIAPITSPRTTRMPLSLMGHNLPVGTTVAPCIYLTHRSP 366 Query 350 VSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAA 409 +P P F+P RFL+ +P +LPFGG RRCLG FAL E ++L + + Sbjct 367 ELYPNPQAFQPERFLERQFSPYEYLPFGGSNRRCLGMTFALFEMKLVLSTLLTGYQFQLE 426 Query 410 GPSKGETPLVRNITTVPKHGAHLRLI-PQRR 439 P + P+ R +T P +H R+I QRR Sbjct 427 QPQPLK-PVRRGVTLAPP--SHFRMILTQRR 454 >gi|254416793|ref|ZP_05030542.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] gi|196176339|gb|EDX71354.1| Cytochrome P450 superfamily [Microcoleus chthonoplastes PCC 7420] Length=458 Score = 239 bits (611), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 136/439 (31%), Positives = 240/439 (55%), Gaps = 27/439 (6%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LP GP+ P LQ + ++ ++ A ++ YGD+F++ + LV + P+ +++I + Sbjct 3 LPDGPQAPAMLQMIHWIAKPFSYMEACNQNYGDIFTVPLGKKFTPLVFVSNPQALQQILS 62 Query 69 ADPRSLHA-GEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 +D + A GE N + ++G SV+ H R R L+MP F ++ Y ++IA + Sbjct 63 SDTKEFDASGEYNELFEPMLGNQSVITLSGKSHRRQRQLMMPPFHGERMKAYGELIAEIT 122 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIH------ 181 + + +W + + M ++L +IL+ VFG+ + E +L+Q++++ Sbjct 123 EQVLHQWEVGKSFSVRSFMQQISLRVILQAVFGLYE----GERYHKLEQLLSMMLDQSST 178 Query 182 PAILAGVPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLL 237 P ++ + +P L++ +PW RF + +ID+++Y EI RR D +RTD+LS L+ Sbjct 179 PGRVSALYFPILRQDLGAWSPWGRFLRQRQQIDQLIYDEINERRDQPD-DSRTDILSMLM 237 Query 238 QTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDD 297 +D +P+TD ELRD+L+TLL+AGHETTA AL+W L+ + PE++ +++ D+ Sbjct 238 SARDEAGQPMTDTELRDELMTLLVAGHETTATALAWALYWIHKLPEVRQKLLEELDSLDN 297 Query 298 ---------GFLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAHA 347 +L AV E +R + V + + R V +P E+ G++L TV+ I L H Sbjct 298 PDPSTLFRLPYLNAVCSETLRIYPVGMLTFPRVVRSPVELMGYQLEPDTVLVGCIYLTHQ 357 Query 348 SEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTIT 407 + +P+P +F+P RFL+ P +LPFGGG RRC+G FA E ++L +I + Sbjct 358 RQDLYPEPKQFKPERFLEHHFYPYEYLPFGGGARRCIGMAFAQFEMKIVLAKILSSCELA 417 Query 408 AAGPSKGETPLVRNITTVP 426 A ++ P+ R + + P Sbjct 418 LAN-NRPVRPVRRGLVSAP 435 >gi|284045204|ref|YP_003395544.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283949425|gb|ADB52169.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=481 Score = 239 bits (610), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 161/448 (36%), Positives = 224/448 (50%), Gaps = 18/448 (4%) Query 8 GLPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIF 67 LPP LPR LQ++ + + F+ R G+ F R + +V+ + P+H+K +F Sbjct 38 ALPPAIPLPRALQTLRFSVRQIEFVFRYRRLLGETFRFRGVVDDEFVVLTSHPDHVKSLF 97 Query 68 AADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 A P + G L ++G +SVL H R R LL+P F A++ Y +MIA+VA Sbjct 98 TAKPDDAPSLTGESPLRPIVGPNSVLTAIGPRHMRQRKLLLPPFHGEAVQRYAEMIAAVA 157 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 I W I A+TLD+I+ +FGV K L+ I + Sbjct 158 DREIDSWPVGKPIRLAPSTQAITLDVIMAGIFGVEGLPEKGTPERGLRDAIRWAVGLSVR 217 Query 188 VPYPSLKRMN--------PWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQT 239 + +N P KR + +D +Y I RR D R D+LS LL+ Sbjct 218 PEAQLFELLNIRREEPAGPLKRLLDH---VDRFVYALIDQRREAGDAAQRADILSLLLEA 274 Query 240 KDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQ------SQVVWAAV 293 D PLTD ELRD+L+TL+LAGHETTA +L+W L P S+ AA Sbjct 275 TDEDGTPLTDRELRDELLTLVLAGHETTANSLAWAFERLVRTPAAYDRLRDISRSGDAAF 334 Query 294 GGDDGFLEAVLKEGMRRHTVIASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHP 353 +DG++EA + E MR VI R+VT P E+G +R+PAGT V SILL H E +P Sbjct 335 ADEDGWIEATIHETMRSRPVIPMIGRRVTRPWELGEYRVPAGTSVAMSILLLHHREDVYP 394 Query 354 KPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSK 413 P FRP RFL TW+PFGGG+RRCLG A+ E V+L+ I RR + A + Sbjct 395 DPFAFRPERFLGVRPGTYTWIPFGGGIRRCLGAALAMAEQRVVLRAIARRTDLVAVD-AA 453 Query 414 GETPLVRNITTVPKHGAHLRLIPQRRLG 441 E RN+T +P+ GA + + +R G Sbjct 454 PEHARHRNVTMIPQEGARVIVQAKRPSG 481 >gi|119485435|ref|ZP_01619763.1| cytochrome P450 [Lyngbya sp. PCC 8106] gi|119457191|gb|EAW38317.1| cytochrome P450 [Lyngbya sp. PCC 8106] Length=457 Score = 238 bits (608), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 149/455 (33%), Positives = 233/455 (52%), Gaps = 30/455 (6%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRV-----PPYADNLVVYTRPEHI 63 LP GPRLP LQ++ + FL ++GD F+LRV PP +V ++ E I Sbjct 3 LPDGPRLPALLQTLQIIAQPTQFLERCANQFGDCFTLRVLGFNSPP----IVFFSNSEAI 58 Query 64 KEIFAADPRSLHAGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMI 123 + IF D G+ H+ + G S++M D H R+R LLMP+ L Y I Sbjct 59 EAIFTTDTDKFELGKITHVFQPLTGSQSLIMQDGKRHQRLRQLLMPSLHSKQLPAYGQTI 118 Query 124 ASVAREHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPA 183 ++ + W P I+ D+ + + L++IL+VV G+ + + +L ++ + Sbjct 119 CNLTLKATQNWSPGDFISIRDYTSEIALEVILQVVLGLKENRRYFQLKHLIEPYLESVNK 178 Query 184 ILAGVPY------PSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLL 237 L + + +L + +PW +F + KID+++Y EIA RR DVLS L+ Sbjct 179 PLNSIQFFLPPLQQNLGQKSPWGKFLKQRKKIDDLIYAEIAERRTKP---LGEDVLSLLI 235 Query 238 QTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVV--WAAVGG 295 KD +PLTD ELRDQLITLLL GH+TTA+AL+W + + P+I +Q+V ++G Sbjct 236 SAKDEAGQPLTDQELRDQLITLLLLGHDTTASALAWAFYWIHRYPKIVNQLVEELNSLGE 295 Query 296 DDG--------FLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAH 346 + +L AV +E +R H + + S R V +I ++ GT++ I LAH Sbjct 296 NPDPMDIVQLPYLNAVCQETLRIHPIALISQPRVVKESIKIENYQFKPGTILVPCIHLAH 355 Query 347 ASEVSHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTI 406 E +P +F P+RFL+ +P +LPFGGG R C+G +L E +IL I + + Sbjct 356 HREQIYPNSKQFNPNRFLEQKFSPYEYLPFGGGNRSCIGMALSLFEMKLILATILLNYQL 415 Query 407 TAAGPSKGETPLVRNITTVPKHGAHLRLIPQRRLG 441 A S P+ R IT VP L ++ +++ G Sbjct 416 -AFNQSHVVKPVRRGITIVPSINFRLTVLTRKQAG 449 >gi|218438521|ref|YP_002376850.1| cytochrome P450 [Cyanothece sp. PCC 7424] gi|218171249|gb|ACK69982.1| cytochrome P450 [Cyanothece sp. PCC 7424] Length=463 Score = 236 bits (602), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 143/443 (33%), Positives = 233/443 (53%), Gaps = 24/443 (5%) Query 16 PRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRSLH 75 P + Q V ++ F +K GD+F + + Y DNLVV P+ I+EIF D Sbjct 12 PSWWQMVQWISDPLSFQQKWAKKCGDIFLINLWRYNDNLVVVGSPQLIQEIFNKDATQFD 71 Query 76 AGEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHITRWR 135 G GN I+ ++G++S+ + D H R R LLMP+F L+ Y I + +E ++W+ Sbjct 72 IGRGNQIVAPLVGQNSLFLMDGTRHKRERKLLMPSFHGERLQTYAQQICEITKEVASQWQ 131 Query 136 PHATINSLDHMNALTLDIILRVVFGVTD----PKVKAELTSRLQQIINIHPAILAGVPY- 190 + M +TL++I++VVFG+ + K+K L + L I + P+ + + Sbjct 132 KDKPFIARTVMQDITLEVIIQVVFGLREGERYQKIKPLLAAMLNMIDSPLPSSFLFLRFL 191 Query 191 -PSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKPLTD 249 L +PW + H Q +I ++L EI RR + + TD+LS ++ +D +P++D Sbjct 192 QKDLGAWSPWGKLKHRQLQIRKLLEAEIEDRRTHNFIG--TDILSLMMAVRDENGEPMSD 249 Query 250 AELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWA--AVGGDDG--------F 299 EL+D+L+TLL AGHETTA L+W +++ PE++ ++V ++G + Sbjct 250 LELKDELMTLLFAGHETTATILAWAFYKIHQLPEVRDKIVQELDSLGEKPNPMEIAKLPY 309 Query 300 LEAVLKEGMRRHTVIASTARKVT-APAEIGGWRLPAGTVVNTSILLAHASEVSHPKPTEF 358 L AV +E +R + VI ++T P +IG + AG + SI L H E +P+P EF Sbjct 310 LNAVCQETLRMYPVIPVLLPRITKTPMDIGDYHFEAGMALMPSIYLVHYREDLYPQPQEF 369 Query 359 RPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAG--PSKGET 416 +P RFLD +P+ ++PFGGG RRCLG+ AL E ++L I + + P K + Sbjct 370 KPERFLDRQYSPSEFIPFGGGSRRCLGYALALLEMKLVLGTILSSYQLALVDNKPVKIQR 429 Query 417 PLVRNITTVPKHGAHLRLIPQRR 439 R +T P G L + +R+ Sbjct 430 ---RGLTLAPVGGVPLVMKSKRQ 449 >gi|119510163|ref|ZP_01629302.1| cytochrome P450 [Nodularia spumigena CCY9414] gi|119465224|gb|EAW46122.1| cytochrome P450 [Nodularia spumigena CCY9414] Length=450 Score = 236 bits (602), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 138/443 (32%), Positives = 236/443 (54%), Gaps = 20/443 (4%) Query 14 RLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAADPRS 73 + P + Q + ++ ++ ++Y D+F+ +V + +NLV P+ ++EI D + Sbjct 8 KTPAFFQQLQWVADPVGYMEKAAQQYPDIFTAQVVGFGNNLVFVNHPQAMQEILTNDRKK 67 Query 74 LHAG-EGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVAREHIT 132 L AG + N IL ++G++S++M D H + R L+MP+F +R Y ++I+++ E + Sbjct 68 LFAGGKENKILQPLLGDYSMIMLDGDRHRKRRQLVMPSFHGDRMRSYGEIISNITEEVWS 127 Query 133 RWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPA------ILA 186 + + + +TL ++++ VFGV + +L +L+ + NI + + Sbjct 128 NLPTDKSFLARNVTQDITLQVMIQAVFGVYQGERSQQLKKQLELMANIFRSPLSSSMLFF 187 Query 187 GVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTPTKP 246 L +PW +F ++ ++D ++Y EIA RR +L R D+LS L+ +D P Sbjct 188 SSLQQDLGAWSPWGKFVRDRQELDNLIYTEIAERR-QQNLENRIDILSLLMSAEDESGNP 246 Query 247 LTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDG-------- 298 +T ELRD+L+TLL AG+ETTA AL+W L+ + PE+Q +++ D Sbjct 247 MTVQELRDELMTLLFAGYETTATALAWGLYFIQKHPEVQEKLLQELDTLGDSPDPMSIFR 306 Query 299 --FLEAVLKEGMRRHTVIAST-ARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSHPKP 355 +L AV E +R H V T R V P EI G+ L GT++ S+ L H E +P+P Sbjct 307 LPYLTAVCNETLRIHPVAMLTFPRTVKEPVEISGYALDPGTILVGSMYLTHQREDLYPEP 366 Query 356 TEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGE 415 +F+P RFL+ +P ++PFGGGVRRC+G A+ E ++L I R+ + A + E Sbjct 367 KQFKPERFLERQFSPYEFIPFGGGVRRCVGEALAVFELKLVLATILSRYEL-ALTDDQPE 425 Query 416 TPLVRNITTVPKHGAHLRLIPQR 438 P R +T P G ++ + QR Sbjct 426 VPRRRGVTLAPGRGVNMMITGQR 448 >gi|186683878|ref|YP_001867074.1| cytochrome P450 [Nostoc punctiforme PCC 73102] gi|186466330|gb|ACC82131.1| cytochrome P450 [Nostoc punctiforme PCC 73102] Length=460 Score = 236 bits (601), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 142/437 (33%), Positives = 233/437 (54%), Gaps = 29/437 (6%) Query 9 LPPGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFA 68 LP GP+ P LQ + ++ F+ ++YGD+F++R+ + L+ ++PE +++I Sbjct 3 LPKGPQSPAVLQMLRWITSPMSFMETCAKRYGDMFTIRLDSKSPPLIFVSKPEVLEQILT 62 Query 69 ADPRSLHA-GEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVA 127 D + L A G+ N + ++G+HSV+ AEH R R LL+P F +R Y +I+ + Sbjct 63 NDIKGLEAPGDTNLVFESLLGKHSVITISGAEHQRQRQLLLPPFHGERMRSYSQIISDIT 122 Query 128 REHITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIHPAILAG 187 + I++++ N A+TL +I++ VFG+ + +L L +++ ++L+ Sbjct 123 EKVISQYQIGQPFNIRSVTQAITLRVIMQAVFGLDEGPRAEKLQHCLAEMLEKGSSVLSA 182 Query 188 --VPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKD 241 + +P+L+R +N W + Q D+++Y EI R+ D +RTD+LS L+ +D Sbjct 183 ALLYFPALQRDFGPINFWGKQMRRQQAADKLIYEEIRERQEQPD-PSRTDILSLLMAARD 241 Query 242 TPTKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWAAVGGDDG--- 298 +P+TD +LRD+L+TLL+AGHETTA AL+W + + P ++ +++ D Sbjct 242 EAGQPMTDEKLRDELMTLLVAGHETTATALAWAFYWIQKIPTVRQKLLKELDSLGDNPDP 301 Query 299 -------FLEAVLKEGMRRHTVIAST-ARKVTAPAEIGGWRLPAGTVVNTSILLAHASEV 350 +L AV E +R + V T AR V P +GG+ L G V SI L H E Sbjct 302 STIFKLPYLNAVCSETLRIYPVAMLTFARVVRTPLSLGGYELEPGIGVIGSIYLTHHRED 361 Query 351 SHPKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAG 410 +P+P +F+P RFL+ +P +LPFGGG RRC+G FA E + L +I Sbjct 362 LYPEPKQFKPERFLERQFSPYEYLPFGGGARRCIGLAFAQLEMKLALAKIL--------- 412 Query 411 PSKGETPLVRNITTVPK 427 S E LV N PK Sbjct 413 -STRELELVDNSEVRPK 428 >gi|166364998|ref|YP_001657271.1| cytochrome P450 [Microcystis aeruginosa NIES-843] gi|166087371|dbj|BAG02079.1| cytochrome P450 [Microcystis aeruginosa NIES-843] Length=461 Score = 235 bits (600), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 144/446 (33%), Positives = 231/446 (52%), Gaps = 20/446 (4%) Query 11 PGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAAD 70 P + P +LQ ++ F+ RK+GD+FS +V DN + + P +++I D Sbjct 5 PKVKAPTFLQMAQWIINPVAFMENAARKHGDIFSTKVGLTVDNFIFVSSPSALQQILTND 64 Query 71 PRSLHA-GEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVARE 129 + A GE N I+ ++G++SV+M D H + R LL+P F +R Y D+I + Sbjct 65 RKQFSAPGEANRIIAPIIGDYSVVMLDGDIHKKRRQLLLPPFHGERMRFYGDLIRDITLR 124 Query 130 HITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIH--PAILAG 187 + + + A+ L +I+ VFG++ + L L ++++I P + + Sbjct 125 VMAELPQNQPFKARSATTAIALQVIMEAVFGISQGERYQTLKKTLAEMLDIFNSPVMASL 184 Query 188 VPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTP 243 + +P L+ +PW ++ Q KID+I+Y EIA R+ + + RTD+LS L+ D Sbjct 185 LFFPILRADFGAWSPWGKYQRYQEKIDDIIYTEIAERKANHN-PNRTDILSLLMSAWDEE 243 Query 244 TKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWA-AVGGDD----- 297 P++D ELRD+L+TLL AGHETTA A+SW L+ PEIQ++++ A GD+ Sbjct 244 GNPMSDKELRDELMTLLFAGHETTATAMSWALYWTHRYPEIQAKILQEIATLGDNPNPID 303 Query 298 ----GFLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSH 352 +L AV E +R H V + + R V P E+ G+ L GT++ I LAH E + Sbjct 304 ITRLPYLSAVCSETLRIHPVGMLTFPRVVEKPVELDGYPLEKGTILMGCIYLAHHREQTF 363 Query 353 PKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPS 412 P F+P RFL+ P ++PFGGG RRC+G A+ E + + I + +T + Sbjct 364 PDSHTFKPERFLEKQFTPYEYMPFGGGARRCIGEVLAIYEMKIAIATILANYQLTLVN-N 422 Query 413 KGETPLVRNITTVPKHGAHLRLIPQR 438 E P R +T P G + L +R Sbjct 423 TPEKPSRRGVTLAPSRGVPMVLKGRR 448 >gi|159028471|emb|CAO87278.1| cyp110A2 [Microcystis aeruginosa PCC 7806] Length=461 Score = 234 bits (597), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 140/446 (32%), Positives = 233/446 (53%), Gaps = 20/446 (4%) Query 11 PGPRLPRYLQSVLYLRFREWFLPAMHRKYGDVFSLRVPPYADNLVVYTRPEHIKEIFAAD 70 P + P ++Q ++ F+ RK+GD+FS +V DN + + P ++++ D Sbjct 5 PKVKAPTFVQMAQWIINPVAFMENAARKHGDIFSTKVGLTVDNFIFVSSPSALQQVLTND 64 Query 71 PRSLHA-GEGNHILGFVMGEHSVLMTDEAEHARMRSLLMPAFTRAALRGYRDMIASVARE 129 + A GE N I+ ++G++SV+M D H + R LL+P F +R Y D+I + Sbjct 65 RKKFSAPGEANRIIAPIIGDYSVIMLDGDIHKKRRQLLLPPFHGERMRFYGDLIRDITLR 124 Query 130 HITRWRPHATINSLDHMNALTLDIILRVVFGVTDPKVKAELTSRLQQIINIH--PAILAG 187 + + + A+ L +I+ VFG++ + L L ++++I P +++ Sbjct 125 VMAELPENQPFKTRSATTAIALQVIMEAVFGISQGERYQTLKKILAEMLDIFNSPVMVSL 184 Query 188 VPYPSLKR----MNPWKRFFHNQTKIDEILYREIASRRIDSDLTARTDVLSRLLQTKDTP 243 + +P L+ +PW ++ Q KID+I+Y EIA R+ + + R+D+LS L+ +D Sbjct 185 LFFPILQADLGAWSPWGKYQRYQAKIDDIIYTEIAERKANPN-PNRSDILSLLMSARDEE 243 Query 244 TKPLTDAELRDQLITLLLAGHETTAAALSWTLWELAHAPEIQSQVVWA-AVGGDDG---- 298 P++D ELRD+L+TLL AGHETTA A+SW L+ PEI+++++ A GD+ Sbjct 244 GNPMSDKELRDELMTLLFAGHETTATAISWVLYWTHRYPEIKAKILKEIATLGDNPNPID 303 Query 299 -----FLEAVLKEGMRRHTV-IASTARKVTAPAEIGGWRLPAGTVVNTSILLAHASEVSH 352 +L AV E +R H V + + R V P E+ G+ L GT++ I LAH E + Sbjct 304 ITRLPYLSAVCSETLRIHPVGMLTFPRVVEEPVELDGYPLEKGTIIMGCIYLAHHREQTF 363 Query 353 PKPTEFRPSRFLDGSVAPNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPS 412 P F+P RFL+ P ++PFGGG RRC+G A+ E + + I + +T + Sbjct 364 PDSHTFKPERFLEKQFTPYEYMPFGGGARRCIGEVLAIYEMKIAIATILANYQLTLVN-N 422 Query 413 KGETPLVRNITTVPKHGAHLRLIPQR 438 E P R +T P G + L +R Sbjct 423 TPEKPSRRGVTLAPSRGVPMVLKGRR 448 Lambda K H 0.322 0.137 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 930863295684 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40