BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0328 Length=200 Score E Sequences producing significant alignments: (Bits) Value gi|15607469|ref|NP_214842.1| TetR/AcrR family transcriptional re... 403 8e-111 gi|340625359|ref|YP_004743811.1| putative transcriptional regula... 402 1e-110 gi|256376800|ref|YP_003100460.1| TetR family transcriptional reg... 121 6e-26 gi|145595289|ref|YP_001159586.1| regulatory protein TetR [Salini... 107 9e-22 gi|302544659|ref|ZP_07297001.1| TetR family transcriptional regu... 106 2e-21 gi|324998078|ref|ZP_08119190.1| putative TetR family transcripti... 106 2e-21 gi|271969951|ref|YP_003344147.1| TetR family transcriptional reg... 104 6e-21 gi|302537106|ref|ZP_07289448.1| TetR-family transcriptional regu... 99.4 2e-19 gi|297562811|ref|YP_003681785.1| TetR family transcriptional reg... 98.6 4e-19 gi|291303066|ref|YP_003514344.1| TetR family transcriptional reg... 98.2 6e-19 gi|345012883|ref|YP_004815237.1| regulatory protein TetR [Strept... 97.1 1e-18 gi|271963032|ref|YP_003337228.1| TetR family transcriptional reg... 97.1 1e-18 gi|333920662|ref|YP_004494243.1| transcriptional regulator [Amyc... 95.1 5e-18 gi|256389255|ref|YP_003110819.1| TetR family transcriptional reg... 93.6 2e-17 gi|302547437|ref|ZP_07299779.1| putative TetR-family transcripti... 93.2 2e-17 gi|328885239|emb|CCA58478.1| Transcriptional regulator, TetR fam... 92.0 4e-17 gi|257056228|ref|YP_003134060.1| transcriptional regulator [Sacc... 91.7 6e-17 gi|284034466|ref|YP_003384397.1| TetR family transcriptional reg... 89.4 3e-16 gi|111019234|ref|YP_702206.1| transcriptional regulator [Rhodoco... 88.6 4e-16 gi|302535814|ref|ZP_07288156.1| regulatory protein [Streptomyces... 87.8 8e-16 gi|302527722|ref|ZP_07280064.1| predicted protein [Streptomyces ... 87.0 1e-15 gi|21222004|ref|NP_627783.1| regulatory protein [Streptomyces co... 86.3 2e-15 gi|311896920|dbj|BAJ29328.1| putative TetR family transcriptiona... 86.3 2e-15 gi|29829269|ref|NP_823903.1| TetR family transcriptional regulat... 86.3 2e-15 gi|302524979|ref|ZP_07277321.1| predicted protein [Streptomyces ... 85.9 3e-15 gi|226973318|gb|ACO94465.1| TetR-type transcriptional regulator ... 84.3 8e-15 gi|333024246|ref|ZP_08452310.1| putative TetR family transcripti... 84.0 1e-14 gi|302522082|ref|ZP_07274424.1| TetR-family transcriptional regu... 84.0 1e-14 gi|318061965|ref|ZP_07980686.1| TetR family transcriptional regu... 84.0 1e-14 gi|300782883|ref|YP_003763174.1| TetR family transcriptional reg... 83.2 2e-14 gi|254383226|ref|ZP_04998579.1| TetR-family transcriptional regu... 82.4 3e-14 gi|226973360|gb|ACO94493.1| TetR-type transcriptional regulator ... 82.4 3e-14 gi|302530329|ref|ZP_07282671.1| predicted protein [Streptomyces ... 78.6 6e-13 gi|289770803|ref|ZP_06530181.1| regulatory protein [Streptomyces... 76.3 3e-12 gi|295836359|ref|ZP_06823292.1| TetR-family transcriptional regu... 75.5 4e-12 gi|345009538|ref|YP_004811892.1| regulatory protein TetR [Strept... 74.7 6e-12 gi|302554338|ref|ZP_07306680.1| transcriptional regulator [Strep... 74.7 7e-12 gi|254385526|ref|ZP_05000852.1| regulatory protein [Streptomyces... 74.3 1e-11 gi|331694261|ref|YP_004330500.1| regulatory protein TetR [Pseudo... 73.9 1e-11 gi|333989892|ref|YP_004522506.1| TetR family transcriptional reg... 73.9 1e-11 gi|271965220|ref|YP_003339416.1| TetR family transcriptional reg... 72.8 3e-11 gi|297202560|ref|ZP_06919957.1| transcriptional regulator [Strep... 72.8 3e-11 gi|297156948|gb|ADI06660.1| putative transcriptional regulator, ... 71.6 5e-11 gi|297191883|ref|ZP_06909281.1| transcriptional regulator [Strep... 70.9 1e-10 gi|294631553|ref|ZP_06710113.1| TetR-family transcriptional regu... 70.1 2e-10 gi|329936825|ref|ZP_08286504.1| transcriptional regulator [Strep... 69.7 2e-10 gi|226940528|ref|YP_002795602.1| transcriptional regulator, TetR... 67.8 1e-09 gi|302558212|ref|ZP_07310554.1| transcriptional regulator [Strep... 66.6 2e-09 gi|319779268|ref|YP_004130181.1| transcriptional regulator,TetR ... 66.2 3e-09 gi|296131736|ref|YP_003638983.1| transcriptional regulator, TetR... 66.2 3e-09 >gi|15607469|ref|NP_214842.1| TetR/AcrR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15839715|ref|NP_334752.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31791506|ref|NP_853999.1| TetR/AcrR family transcriptional regulator [Mycobacterium bovis AF2122/97] 78 more sequence titles Length=200 Score = 403 bits (1035), Expect = 8e-111, Method: Compositional matrix adjust. Identities = 199/200 (99%), Positives = 200/200 (100%), Gaps = 0/200 (0%) Query 1 VQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR 60 +QQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR Sbjct 1 MQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR 60 Query 61 CFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALR 120 CFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALR Sbjct 61 CFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALR 120 Query 121 ERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 ERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR Sbjct 121 ERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 Query 181 STEVIRALASIGAVVTSQLR 200 STEVIRALASIGAVVTSQLR Sbjct 181 STEVIRALASIGAVVTSQLR 200 >gi|340625359|ref|YP_004743811.1| putative transcriptional regulatory protein [Mycobacterium canettii CIPT 140010059] gi|340003549|emb|CCC42670.1| putative transcriptional regulatory protein (possibly TETR/ACRR-family) [Mycobacterium canettii CIPT 140010059] Length=200 Score = 402 bits (1034), Expect = 1e-110, Method: Compositional matrix adjust. Identities = 198/200 (99%), Positives = 200/200 (100%), Gaps = 0/200 (0%) Query 1 VQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR 60 +QQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR Sbjct 1 MQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR 60 Query 61 CFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALR 120 CFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALR Sbjct 61 CFSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALR 120 Query 121 ERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 ERLAAGYADVRQHSVDLAGAALAGTD+APPENLSTIVSVLMAVIDGLMIQWIADPSATPR Sbjct 121 ERLAAGYADVRQHSVDLAGAALAGTDVAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 Query 181 STEVIRALASIGAVVTSQLR 200 STEVIRALASIGAVVTSQLR Sbjct 181 STEVIRALASIGAVVTSQLR 200 >gi|256376800|ref|YP_003100460.1| TetR family transcriptional regulator [Actinosynnema mirum DSM 43827] gi|255921103|gb|ACU36614.1| transcriptional regulator, TetR family [Actinosynnema mirum DSM 43827] Length=210 Score = 121 bits (304), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 77/194 (40%), Positives = 107/194 (56%), Gaps = 5/194 (2%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +RD+LLDGA CL ERGY NT++RDI A+ N+ASI YHFGSK+ALL AL F W Sbjct 3 HRDQLLDGAKKCLYERGYSNTTARDIVAASNTNLASIGYHFGSKEALLSAALVSAFEEWG 62 Query 67 QRVQEAF-DHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 + D AG++ + ++S RP A +E+++ A R LRE+LA+ Sbjct 63 NELDRVMADVGTDPTVAGRLETMWAGVLESITTHRPLWVAGIEAFSLAERMPDLREKLAS 122 Query 126 GYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVI 185 Y R+ L LAGTD L+ S L+AV+ GL +Q + DP A P ++++I Sbjct 123 TY---RRARPSLGQLTLAGTDAEERTRLAA-GSFLLAVMTGLTVQSLLDPEAVPEASDLI 178 Query 186 RALASIGAVVTSQL 199 A+ SI QL Sbjct 179 TAVRSIFGRFDVQL 192 >gi|145595289|ref|YP_001159586.1| regulatory protein TetR [Salinispora tropica CNB-440] gi|145304626|gb|ABP55208.1| regulatory protein, TetR [Salinispora tropica CNB-440] Length=198 Score = 107 bits (267), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 75/196 (39%), Positives = 102/196 (53%), Gaps = 15/196 (7%) Query 6 TNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTW 65 ++R++LL GA CL ERGY T++RDI A+G N+ASI YHFGSK+ALL AL + F W Sbjct 5 SHRERLLAGARNCLYERGYTRTTARDIVAASGTNLASIGYHFGSKEALLTAALVQAFEEW 64 Query 66 NQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 V ++ ++ V SF RP A +E++A A ALRE+LA Sbjct 65 GVEVDRVLRDGTQPDLMDRLESMWTDLVRSFGIHRPLWVAGIEAFALAEHLPALREQLAE 124 Query 126 GYADVRQHSVDLAGAALA------GTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATP 179 YA R ALA G + E + S L+A++ GL +Q + DP+A P Sbjct 125 SYARARP--------ALATFVIRDGGENVDDETRKAVGSFLLALMTGLTVQRLLDPAAAP 176 Query 180 RSTEVIRALASI-GAV 194 E+ AL I GAV Sbjct 177 SGKELAEALRLIVGAV 192 >gi|302544659|ref|ZP_07297001.1| TetR family transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gi|302462277|gb|EFL25370.1| TetR family transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length=198 Score = 106 bits (265), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 71/188 (38%), Positives = 103/188 (55%), Gaps = 12/188 (6%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R++L+ GA CL ERGY T+SRDIA AA + +INYH+ SK+ALL+ AL W Sbjct 9 HREQLMAGAKQCLEERGYARTTSRDIAAAANAPLGTINYHYASKEALLNAALLEMLQEWG 68 Query 67 QRVQEAFDHSRAAGPAG-QILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 +V RA AG ++ ++ E V+S RP + A E+ A A R +R+++A Sbjct 69 DKV-------RAQSAAGRRVESMWERVVESEATDRPLLVASAEALAQAERFPEIRQQIAE 121 Query 126 GYADVR-QHSVDLAGAALAGTDIAPPENLSTIV-SVLMAVIDGLMIQWIADPSATPRSTE 183 + R + + DL G + TD A + L+ V SV MA++ GL QW+ DP P + E Sbjct 122 AFERSRTEMAADLHG--IDATDSAEHKELARAVGSVHMALVAGLTQQWLIDPEHAPSARE 179 Query 184 VIRALASI 191 V L I Sbjct 180 VAAGLRRI 187 >gi|324998078|ref|ZP_08119190.1| putative TetR family transcriptional regulator [Pseudonocardia sp. P1] Length=198 Score = 106 bits (264), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 65/189 (35%), Positives = 102/189 (54%), Gaps = 5/189 (2%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R++LLDGA CL E+G+G T++RD+ A+G N+ASI YHFGSKDALL +AL R + W Sbjct 3 HREELLDGAAQCLYEKGFGRTTARDVVAASGTNLASIGYHFGSKDALLTEALLRATTAWG 62 Query 67 QRVQEAF---DHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERL 123 + + A D + + P ++ + F R VE+ A A R LR +L Sbjct 63 EELDRALAEPDGAATSDPDRRVEDTWGRVISLFSTQRRLWATHVEALAQAERLPELRAKL 122 Query 124 AAGYADVRQHSVDLAGAALAGTDIAPPE-NLSTIVSVLMAVIDGLMIQWIADPSATPRST 182 A +VR+ + L L D A + + + +V A++ G+M+QW+ DP + P Sbjct 123 AEAQHEVRE-GLALTFHTLPDDDPAAADRRVHVLGAVYQALLTGVMVQWMLDPESAPSGV 181 Query 183 EVIRALASI 191 ++ L +I Sbjct 182 DLAEGLRAI 190 >gi|271969951|ref|YP_003344147.1| TetR family transcriptional regulator [Streptosporangium roseum DSM 43021] gi|270513126|gb|ACZ91404.1| putative transcriptional regulator, TetR family [Streptosporangium roseum DSM 43021] Length=202 Score = 104 bits (260), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 73/195 (38%), Positives = 105/195 (54%), Gaps = 11/195 (5%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAG-VNIASINYHFGSKDALLDDALGRCFSTW 65 NR+ LL GA CL E+G+ T+ RDI+ A+G V++A+I YHFGS++ALL+ AL + W Sbjct 3 NREDLLAGARRCLEEKGWARTTVRDISAASGGVSMAAIGYHFGSREALLNAALIQAIDEW 62 Query 66 NQ---RVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRER 122 R A+ + PA Q A+ ++SF R A VE+ A S LRE Sbjct 63 GTETGRTLAAYGDP-GSSPAEQYEAMWSQMIESFTAHRKLWLASVEALLQAEHSSELREY 121 Query 123 LAAGYADVRQHSVDLAGAALAGT--DIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 LA + R LA A L G D P + T+ SV +A++ G+M+QW+ DP +P Sbjct 122 LAGSQKEGRS---GLA-AILRGVPEDELPDSTVRTLGSVQLALLSGVMVQWLTDPGRSPS 177 Query 181 STEVIRALASIGAVV 195 EV+ L +I A + Sbjct 178 GPEVLEGLRAIVATI 192 >gi|302537106|ref|ZP_07289448.1| TetR-family transcriptional regulator [Streptomyces sp. C] gi|302446001|gb|EFL17817.1| TetR-family transcriptional regulator [Streptomyces sp. C] Length=202 Score = 99.4 bits (246), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 68/201 (34%), Positives = 102/201 (51%), Gaps = 17/201 (8%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +++ LL+GA CL E+G+ T++RD+ A+G N+ASI YH+GSKDALL A W Sbjct 3 HKEDLLEGAKKCLVEKGFVRTTARDVVGASGTNLASIGYHYGSKDALLTQAFIALMQEWG 62 Query 67 QRVQEAFDHSRAA--GPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 + AF G ++ A+ + + + P A +E R LR LA Sbjct 63 ET---AFRGGLPGEDGSLERLRAIWDGVLAQHDASAPVWAASMEVALSGERLPQLRGMLA 119 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLS-----TIVSVLMAVIDGLMIQWIADPSATP 179 A A+ R+ + L L GT P E L+ T+ SV+ A+++GLMIQW+ DP T Sbjct 120 ASQAEGRRGLISL----LTGT---PEEELTEHDERTLGSVVQALLNGLMIQWLLDPGTTS 172 Query 180 RSTEVIRALASIGAVVTSQLR 200 + E L + +T+ LR Sbjct 173 SAEEFTEGLRRLAEGLTASLR 193 >gi|297562811|ref|YP_003681785.1| TetR family transcriptional regulator [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296847259|gb|ADH69279.1| transcriptional regulator, TetR family [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=190 Score = 98.6 bits (244), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 62/187 (34%), Positives = 96/187 (52%), Gaps = 10/187 (5%) Query 6 TNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTW 65 + R+ LL GA CL E+GY T++RDIA A+G ++ASI YHFGSKD L++ A+ W Sbjct 2 SQREDLLAGARKCLVEKGYSKTTARDIAAASGAHLASIGYHFGSKDNLMNTAVIEATGEW 61 Query 66 NQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 A SRA PA ++ +L++ + + R + A V++YA A + +R LA Sbjct 62 GDTFGAAVSASRAEAPADRLRVLLDSLFRTLPEERDLLVASVQAYAQAQFDDGVRAVLAE 121 Query 126 GYADVRQHSVDLAGAALAGTDIAP----PENLSTIVSVLMAVIDGLMIQWIADPSATPRS 181 G R+ G A D+ P P + + S+ + G +IQ++ DP A P Sbjct 122 GLRGARR------GLAALLLDLEPGEVDPAVEAGLGSMAYNFVTGYLIQYLIDPEALPTV 175 Query 182 TEVIRAL 188 + + L Sbjct 176 EQAVEGL 182 >gi|291303066|ref|YP_003514344.1| TetR family transcriptional regulator [Stackebrandtia nassauensis DSM 44728] gi|290572286|gb|ADD45251.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis DSM 44728] Length=195 Score = 98.2 bits (243), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 65/191 (35%), Positives = 105/191 (55%), Gaps = 12/191 (6%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR++LLD A CL ++GY T+ RDI+ AGV+ A+I YHFGSK+ALL+ AL + Sbjct 3 NREQLLDAAKQCLIQKGYERTTVRDISDLAGVSKAAIGYHFGSKEALLNAALFEVLGGGD 62 Query 67 QRVQ---EAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYAC-VESYAPALRSEALRER 122 + EA D A P + A+ + ++ +A +ES A R ++RE Sbjct 63 SGLSPTAEAADPD--ATPVQRFTALWTNMMAAYGGEDKTFWAANLESVLVAYRDASVREH 120 Query 123 LAAGYADVRQHSVDLAGAALAGTDIA--PPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 L+AG+ + R + L G + + PPE + T+ SV MA++ G+MIQ++ +P P Sbjct 121 LSAGFEEGRSGITSV----LTGVEESQVPPETIRTLGSVQMALLSGVMIQYLVNPDTAPS 176 Query 181 STEVIRALASI 191 + E+ R + ++ Sbjct 177 AEELFRGIHAL 187 >gi|345012883|ref|YP_004815237.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344039232|gb|AEM84957.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=186 Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/191 (36%), Positives = 100/191 (53%), Gaps = 12/191 (6%) Query 12 LDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQ- 70 + GA CL ERG+ T+SRDIA AA + +INYH+GSK+ LL+ AL W+++V+ Sbjct 1 MAGAKRCLEERGFARTTSRDIAAAANAPLGTINYHYGSKEQLLNAALLESLDEWSEKVRS 60 Query 71 ---EAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGY 127 EA S A A + A + ++S RP + A E++A A RS +R++LA + Sbjct 61 GSAEAAPDSDAGTRAESMWARI---IESETTDRPLLVAGAEAFAQAERSAEVRQQLAEAF 117 Query 128 ADVRQHSVDLAGAALAGTDIAPPENLSTIV-SVLMAVIDGLMIQWIADPSATPRSTEVIR 186 + S A L G + A ++ V SV MA++ GL QW+ DP P + EV Sbjct 118 ----ERSRTALAAELHGIEDAEEGEVARAVGSVHMALVAGLTQQWLVDPERAPSAREVAT 173 Query 187 ALASIGAVVTS 197 L I + S Sbjct 174 GLRRIAQALES 184 >gi|271963032|ref|YP_003337228.1| TetR family transcriptional regulator [Streptosporangium roseum DSM 43021] gi|270506207|gb|ACZ84485.1| putative transcriptional regulator, TetR family [Streptosporangium roseum DSM 43021] Length=216 Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/208 (33%), Positives = 101/208 (49%), Gaps = 17/208 (8%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ LL GA CL E+GY T++RDIA A+GV++A+I YHF SK+AL++ AL + W Sbjct 3 NREDLLAGAKRCLYEKGYTRTTARDIAAASGVSLAAIGYHFKSKEALMNTALFQAMQEWG 62 Query 67 QRVQEAFDHSRAAG--PAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 ++ A G PA + A + + SF RP E A R +RE+LA Sbjct 63 DEIERALTAGTDPGATPAERFEATWDQVIASFAAHRPVWATQFELIAQIDRLPEIREQLA 122 Query 125 A-------GYADVRQH-SVDLAGA-------ALAGTDIAPPENLSTIVSVLMAVIDGLMI 169 A G A++ Q V L A AG E + S+ A++ G++ Sbjct 123 ASMDAARLGLAEMFQSIGVPLGEAPPGETASGEAGAGATGDERARVVGSLYQAMLSGVLA 182 Query 170 QWIADPSATPRSTEVIRALASIGAVVTS 197 QW+ DP P ++ AL +G + + Sbjct 183 QWLVDPGQAPSGRDLADALRIVGGTMNA 210 >gi|333920662|ref|YP_004494243.1| transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333482883|gb|AEF41443.1| Transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] Length=195 Score = 95.1 bits (235), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 59/182 (33%), Positives = 90/182 (50%), Gaps = 1/182 (0%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL A + E+GY ++RD+ +G N+ASI YHFGSK+ALL+ A+ FS W Sbjct 3 HREDLLAAAGKLISEKGYARITARDLVAESGTNLASIGYHFGSKEALLNAAIFEAFSDWT 62 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAG 126 + ++ P + + A +D F +P + A E+ A A R+ LR + A Sbjct 63 TYLANTAMTAQVNSPHERAVITWAAMLDGFRDQQPMLVALAEALAQAERTPELRTQFAEQ 122 Query 127 YADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIR 186 Y +R A+ G P + I S ++AV DG +QW+ D TP E+I Sbjct 123 YRAIRGRVAGYVAEAVNGLSAEDPRT-TAIASFMIAVCDGFAMQWLIDADNTPSPAELIS 181 Query 187 AL 188 L Sbjct 182 GL 183 >gi|256389255|ref|YP_003110819.1| TetR family transcriptional regulator [Catenulispora acidiphila DSM 44928] gi|256355481|gb|ACU68978.1| transcriptional regulator, TetR family [Catenulispora acidiphila DSM 44928] Length=205 Score = 93.6 bits (231), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 63/200 (32%), Positives = 105/200 (53%), Gaps = 13/200 (6%) Query 6 TNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTW 65 +NRD LL GA CL E+GY T++RDIA+A+GV++A+I YHFGSKDAL+++A+ + W Sbjct 2 SNRDDLLAGAKKCLLEKGYSRTTARDIAQASGVSLAAIGYHFGSKDALMNEAMFQAIGEW 61 Query 66 NQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 ++EAF AG L+V E F+ + + + +R+ Sbjct 62 GDHLEEAF------AKAGPNLSVQERFARVFDDVSATFDENQALWMASFELIIEIDRI-P 114 Query 126 GYADVRQHSVDLAGAALAGTDIA-PPENLSTIV-----SVLMAVIDGLMIQWIADPSATP 179 G D+ + ++ A LA + P E++ + +VL +++ GL+IQ AD TP Sbjct 115 GARDMFRKAIPEARTGLANLILGIPEEDVDKDMEMGAGAVLYSLMAGLLIQRFADTGQTP 174 Query 180 RSTEVIRALASIGAVVTSQL 199 ++ R L + V+ + + Sbjct 175 TGADLARGLRQLADVLEADV 194 >gi|302547437|ref|ZP_07299779.1| putative TetR-family transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gi|302465055|gb|EFL28148.1| putative TetR-family transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length=198 Score = 93.2 bits (230), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 55/187 (30%), Positives = 91/187 (49%), Gaps = 6/187 (3%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL GA CL E+GY T++RDI A+G N+ASI YH+G+K+ALL+ A+ W Sbjct 3 HREDLLVGAKRCLYEKGYARTTARDIVEASGTNLASIGYHYGTKEALLNAAIMEALEEWA 62 Query 67 QRVQEAFDH--SRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 Q ++ A P G+ ++ FE+ RP A E+ + +R + Sbjct 63 QELKRAVADVGDLPDDPIGRFERAWTRVIELFERHRPVWAAQFEAISQIEHVPEVRSFIV 122 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 ++ V+L L G + PP + + A++ G+M+QW+ DP + Sbjct 123 DAQQQAQKGLVEL----LLGGEELPPHTRAAVGQFYHALLSGVMMQWVIDPEHASTGASL 178 Query 185 IRALASI 191 AL ++ Sbjct 179 AEALRTV 185 >gi|328885239|emb|CCA58478.1| Transcriptional regulator, TetR family [Streptomyces venezuelae ATCC 10712] Length=191 Score = 92.0 bits (227), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 61/186 (33%), Positives = 87/186 (47%), Gaps = 7/186 (3%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +++ LL+GA CL E+GYG T++RDI A+G N+ASI YH+GSKDALL A W Sbjct 3 HKEDLLEGAKRCLLEKGYGRTTARDIVAASGTNLASIGYHYGSKDALLQQAFLALTEEWG 62 Query 67 QRVQEAFDHSRA----AGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRER 122 + V A A P + AV + + + E RP E E LRE Sbjct 63 EAVGPAGSGEEKQELPADPYQRFHAVWQQVIGAAEASRPVWKLQTEVVTRLDDDEKLREA 122 Query 123 LAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRST 182 + R+ + +A L A PE + A+ G+MIQW+ DP P + Sbjct 123 IK---EPQREGRLGMAEGMLGIDPEAEPEKARVAGLLCQALAAGVMIQWMVDPETAPSAD 179 Query 183 EVIRAL 188 ++ L Sbjct 180 DLTEGL 185 >gi|257056228|ref|YP_003134060.1| transcriptional regulator [Saccharomonospora viridis DSM 43017] gi|256586100|gb|ACU97233.1| transcriptional regulator [Saccharomonospora viridis DSM 43017] Length=196 Score = 91.7 bits (226), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 51/163 (32%), Positives = 83/163 (51%), Gaps = 0/163 (0%) Query 22 RGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGP 81 +GY + ++RD+ +G N+ASI YHFGSK LL++A+G W +++ AA Sbjct 18 KGYAHITARDLVAESGTNLASIGYHFGSKAGLLNEAIGEAMQDWTEQLARIAMADPAAST 77 Query 82 AGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHSVDLAGAA 141 A + L+ A ++ + R V + +E+ A A R LRE+ A Y R +L + Sbjct 78 AERGLSAWSAMLEGLVRERELVVSYLEALAQAEREPVLREQFAEQYRRCRARVAELVAES 137 Query 142 LAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 L ++ + S ++AV DGL +QW+ DP P E+ Sbjct 138 LGEGARPDDPSVKAVASFVIAVCDGLAVQWVLDPDELPTGEEL 180 >gi|284034466|ref|YP_003384397.1| TetR family transcriptional regulator [Kribbella flavida DSM 17836] gi|283813759|gb|ADB35598.1| transcriptional regulator, TetR family [Kribbella flavida DSM 17836] Length=195 Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 64/188 (35%), Positives = 95/188 (51%), Gaps = 5/188 (2%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAG-VNIASINYHFGSKDALLDDALGRCFSTW 65 NR+ LL GA CL+ +G+ T+ RDI AAG V++A+I YHFGSK+ALL +AL + W Sbjct 3 NRESLLAGARKCLQTKGFAQTTVRDITEAAGGVSMAAIGYHFGSKEALLTEALVQLTEEW 62 Query 66 NQRVQEAFDHS-RAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 ++V++A S PA + + + S R E A A + A+RER+ Sbjct 63 GRQVEDALSASDEQLEPAARFAVAWDRLLQSALANRRLWAVTFEVIASADQVPAVRERIL 122 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 AG R + G L D E+ + S+ A++ GLM Q + DP +++ Sbjct 123 AGLGQARDGLLQNLGHPL---DADNAESTWAVGSLYQALLTGLMAQSLIDPDHVVTGSQL 179 Query 185 IRALASIG 192 A A IG Sbjct 180 AHAFAEIG 187 >gi|111019234|ref|YP_702206.1| transcriptional regulator [Rhodococcus jostii RHA1] gi|110818764|gb|ABG94048.1| probable transcriptional regulator [Rhodococcus jostii RHA1] Length=189 Score = 88.6 bits (218), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 62/187 (34%), Positives = 95/187 (51%), Gaps = 7/187 (3%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ L+DGA L ++GY T++RDIA A+GV++A+I YHFG+K+ALL AL R W Sbjct 3 NREDLIDGAARSLYDKGYSRTTARDIASASGVSLAAIGYHFGTKEALLHAALYREMERWG 62 Query 67 QRVQEAFDHSRAAG--PAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 + A G P + A+ ++SF R E LR+ L Sbjct 63 DDLATAAAKKIEPGMSPTERFEAIWAGVIESFTAHRRLWMLQFELLGHLDSLPELRKNLV 122 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 A AD R+ V+L G AG + P T+ ++ A++ G+ QW+ DP + E+ Sbjct 123 ASTADAREGLVELFGD--AGIE---PGRAHTLGALYQALLLGVAEQWLVDPDHAMSAGEL 177 Query 185 IRALASI 191 + AL ++ Sbjct 178 LTALRAL 184 >gi|302535814|ref|ZP_07288156.1| regulatory protein [Streptomyces sp. C] gi|302444709|gb|EFL16525.1| regulatory protein [Streptomyces sp. C] Length=195 Score = 87.8 bits (216), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 64/188 (35%), Positives = 95/188 (51%), Gaps = 16/188 (8%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ LL GA CL E+GY T+ RDIA AA V++A+I YHFGS++ALL+ AL W Sbjct 3 NREDLLAGARRCLEEKGYSRTTVRDIATAAQVSMAAIGYHFGSREALLNQALFAAMDDW- 61 Query 67 QRVQEAFDHSRAAG----PAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRER 122 A R G PA + + + F +R A +E++ A S L Sbjct 62 -----AAGSGRLTGQGDTPAERYGDTWDRKIRDFLDMRWLWIANIEAFVHAQSSPELLAI 116 Query 123 LAAGYADVRQHSVDLAGAALAGT--DIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 LA G ++ S + A LAG + E++ + SV +A++ G+M+Q + DP P Sbjct 117 LAEG----QRRSRRMVAAHLAGVSEEAVTDEDVRALGSVHLALLSGVMVQALTDPGQAPT 172 Query 181 STEVIRAL 188 E+ + L Sbjct 173 GAELTQGL 180 >gi|302527722|ref|ZP_07280064.1| predicted protein [Streptomyces sp. AA4] gi|302436617|gb|EFL08433.1| predicted protein [Streptomyces sp. AA4] Length=183 Score = 87.0 bits (214), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 60/183 (33%), Positives = 90/183 (50%), Gaps = 9/183 (4%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ L+ A CL + GY T+ RD+ A+G N ASINYHFGSKD LL AL + W Sbjct 3 HRENLITAARECLLKAGYARTTVRDLVAASGANQASINYHFGSKDQLLTQALFDLNTEWG 62 Query 67 QRVQEAFDH--SRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 + + AGP + ++E S ++ R + ES + E +R+ A Sbjct 63 EMLFAVLTDPADEKAGPERRWARIIE----SIQEHRELWFVNFESVSYLQHDETIRKINA 118 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 G RQ V LA A A PE++ I + +++ G +QW+ DP P + +V Sbjct 119 EGQ---RQARVALANAFGGLGPDADPEDVHAIGTHYYSLLVGTALQWLTDPDNAPSAADV 175 Query 185 IRA 187 +RA Sbjct 176 VRA 178 >gi|21222004|ref|NP_627783.1| regulatory protein [Streptomyces coelicolor A3(2)] gi|4726006|emb|CAB41735.1| putative regulatory protein [Streptomyces coelicolor A3(2)] Length=197 Score = 86.3 bits (212), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 62/187 (34%), Positives = 92/187 (50%), Gaps = 8/187 (4%) Query 17 ACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFD-- 74 A R++G+ + RDIA A+GV++A+I Y FGS++ALL AL W R+ Sbjct 15 AAWRKKGWARITVRDIAAASGVSMAAIGYRFGSREALLTSALIEAIDEWGTRLGRTLSAY 74 Query 75 HSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHS 134 S A A A+ A + SF + R A +E+ A S+ LR LA G A R+ Sbjct 75 GSEGASAAEHYEALWAAVIGSFTEDRTLWLATLEALVQAEHSDDLRRYLATGQAQGRRGL 134 Query 135 VDLAGAALAGT--DIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIRALASIG 192 L L GT D + S +A+ GLM QW+ DP PR+ +V+ L ++ Sbjct 135 AAL----LRGTSEDDIDDATARSPGSTQLALFTGLMTQWLTDPDQAPRAPKVVSGLRALT 190 Query 193 AVVTSQL 199 +V S++ Sbjct 191 HLVRSEV 197 >gi|311896920|dbj|BAJ29328.1| putative TetR family transcriptional regulator [Kitasatospora setae KM-6054] Length=192 Score = 86.3 bits (212), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 71/199 (36%), Positives = 97/199 (49%), Gaps = 17/199 (8%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ LL A CL+E+GYG T++RDIA AGV++A+I YH+GSKDALL +AL + W Sbjct 3 NREDLLASAARCLQEKGYGRTTARDIASGAGVSLAAIGYHYGSKDALLVEALVQAMGEWG 62 Query 67 QRVQEAFDHSRAA---GPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERL 123 + + A S AA P + + +A DSF R E L ERL Sbjct 63 EVIGAAL--SAAADVDDPRERFVRAWDAVRDSFTTHRGLWTVQFELLGQFAHLPGLPERL 120 Query 124 AAGYADVRQHSVDLAGAAL----AGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATP 179 A Q + L AAL A + P E I +++ G QW+ DP+ P Sbjct 121 AGA-----QKAGRLGLAALFQGRAEEEDTPDELARGI--FYQSLLLGQAAQWLIDPAIAP 173 Query 180 RSTEVIRALASI-GAVVTS 197 E +R LA + G V+T Sbjct 174 GGEEFLRGLALVSGDVLTG 192 >gi|29829269|ref|NP_823903.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29606376|dbj|BAC70438.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=196 Score = 86.3 bits (212), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 59/175 (34%), Positives = 86/175 (50%), Gaps = 8/175 (4%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL E+G+ T++RDI + +G N+ASI YH+GSKDALL +A S Sbjct 3 HREDLLEGAKRCLVEKGFVRTTARDIVKESGTNLASIGYHYGSKDALLAEAYVDLISNVG 62 Query 67 QRVQEAFDHSRAAGPAGQILAVLEA---TVDSFEQIRPAVYACVESYAPALRSEALRERL 123 AFD A G G + EA + SF + RP E A R +RE L Sbjct 63 DTFG-AFDEGAATGEPGSLERFEEAWRGVIRSFTEARPIWLLTFEVVTNADRLPTVREHL 121 Query 124 AAGYADVRQHSVDL-AGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSA 177 + R+ + + G D E L T+ +++GL +QW+ DP + Sbjct 122 VKAQDEGRRGLIPMFMGGREEDVD---DEALRTLGGFYQTLLNGLCLQWLFDPDS 173 >gi|302524979|ref|ZP_07277321.1| predicted protein [Streptomyces sp. AA4] gi|302433874|gb|EFL05690.1| predicted protein [Streptomyces sp. AA4] Length=162 Score = 85.9 bits (211), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 75/188 (40%), Positives = 96/188 (52%), Gaps = 34/188 (18%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ LL GA CL E G+GNT+ RDIA AAGV+ A+I YHFGS+DALL AL Sbjct 3 NREDLLAGAKRCLIELGWGNTTVRDIAAAAGVSHAAIGYHFGSRDALLTQALVAAVDELG 62 Query 67 QRVQE-AFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 +V + +FD S L+ +DSF + R A +E+ A RS Sbjct 63 GQVADSSFDLSEQG---------LKRLIDSFGEHRALWVAQLEALVQAERS--------- 104 Query 126 GYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV- 184 ADVRQH V A AG A V A++ GLM+QW+ DP P + EV Sbjct 105 --ADVRQHLVQGLREARAGVGGA----------VQSALVIGLMVQWLLDPQEAPSAKEVA 152 Query 185 --IRALAS 190 IRA+A+ Sbjct 153 DGIRAVAA 160 >gi|226973318|gb|ACO94465.1| TetR-type transcriptional regulator [Streptomyces sp. DSM 21069] Length=198 Score = 84.3 bits (207), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 51/187 (28%), Positives = 89/187 (48%), Gaps = 6/187 (3%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL GA CL E+GY T++RDI A+G N+ASI YH+G+K+ALL+ A+ W Sbjct 3 HREDLLAGAKQCLYEKGYARTTARDIVEASGTNLASIGYHYGTKEALLNAAIMEALEEWA 62 Query 67 QRVQEAFDH--SRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 Q ++ A P + ++ FE+ RP A + A+ + Sbjct 63 QELKSALADVGDLPDDPIKRFEVAWTRVIELFERHRPVWGAQFD----AISQRDHVPEVG 118 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 + + + +Q + + L G + P + + A++ G+M+QW+ DP + Sbjct 119 SFFIEAQQQAQNGLVRLLWGGEELPGPTATAVGQFYHALLSGVMMQWVVDPEHASTGESL 178 Query 185 IRALASI 191 AL ++ Sbjct 179 AEALRTV 185 >gi|333024246|ref|ZP_08452310.1| putative TetR family transcriptional regulator [Streptomyces sp. Tu6071] gi|332744098|gb|EGJ74539.1| putative TetR family transcriptional regulator [Streptomyces sp. Tu6071] Length=196 Score = 84.0 bits (206), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 67/188 (36%), Positives = 92/188 (49%), Gaps = 10/188 (5%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL E+G+ T++RDI R +G N+ASI YH+GSKDALL A + Sbjct 3 HREDLLEGAKFCLLEKGFAATTARDIVRESGANLASIGYHYGSKDALLGRAYVALVEEMD 62 Query 67 QRVQEAFDHSRA-AGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 R E + A G A EA + SF R E R A R+ L A Sbjct 63 LRPPEGAPGADAPPGTLAHFRATWEAVLASFPAQRAVWRLSFEMVLFGDRWPAARDVLIA 122 Query 126 GYADVRQHSVDLAGAALAG--TDIAPPENLSTIVSVLMAVIDGLMIQWIADP-SAT--PR 180 R + AA G D PPE + T + +++GL++QW+ DP SAT R Sbjct 123 SQPAGRAGLL----AAFTGLDEDALPPELVETEGRFHLTLLNGLILQWLFDPESATTAER 178 Query 181 STEVIRAL 188 TE +R+ Sbjct 179 LTEGVRSF 186 >gi|302522082|ref|ZP_07274424.1| TetR-family transcriptional regulator [Streptomyces sp. SPB78] gi|302430977|gb|EFL02793.1| TetR-family transcriptional regulator [Streptomyces sp. SPB78] Length=196 Score = 84.0 bits (206), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 67/188 (36%), Positives = 92/188 (49%), Gaps = 10/188 (5%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL E+G+ T++RDI R +G N+ASI YH+GSKDALL A + Sbjct 3 HREDLLEGAKFCLLEKGFAATTARDIVRESGANLASIGYHYGSKDALLGRAYVALVEEMD 62 Query 67 QRVQEAFDHSRA-AGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 R E + A G A EA + SF R E R A R+ L A Sbjct 63 LRPPEGAPGADAPPGTLAHFRATWEAVLASFPAQRAVWRLSFEMVLFGDRWPAARDVLIA 122 Query 126 GYADVRQHSVDLAGAALAG--TDIAPPENLSTIVSVLMAVIDGLMIQWIADP-SAT--PR 180 R + AA G D PPE + T + +++GL++QW+ DP SAT R Sbjct 123 SQPAGRAGLL----AAFTGLDEDALPPELVETEGRFHLTLLNGLILQWLFDPESATTAER 178 Query 181 STEVIRAL 188 TE +R+ Sbjct 179 LTEGVRSF 186 >gi|318061965|ref|ZP_07980686.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actG] gi|318079292|ref|ZP_07986624.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actF] Length=196 Score = 84.0 bits (206), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 67/188 (36%), Positives = 92/188 (49%), Gaps = 10/188 (5%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL E+G+ T++RDI R +G N+ASI YH+GSKDALL A + Sbjct 3 HREDLLEGAKFCLLEKGFAATTARDIVRESGANLASIGYHYGSKDALLGRAYVALVEEMD 62 Query 67 QRVQEAFDHSRA-AGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA 125 R E + A G A EA + SF R E R A R+ L A Sbjct 63 LRPPEGAPGADAPPGTLAHFRATWEAVLASFPAQRAVWRLSFEMVLFGDRWPAARDVLIA 122 Query 126 GYADVRQHSVDLAGAALAG--TDIAPPENLSTIVSVLMAVIDGLMIQWIADP-SAT--PR 180 R + AA G D PPE + T + +++GL++QW+ DP SAT R Sbjct 123 SQPAGRAGLL----AAFTGLDEDALPPELVETEGRFHLTLLNGLILQWLFDPESATTAER 178 Query 181 STEVIRAL 188 TE +R+ Sbjct 179 LTEGVRSF 186 >gi|300782883|ref|YP_003763174.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299792397|gb|ADJ42772.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340524258|gb|AEK39463.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=190 Score = 83.2 bits (204), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 59/188 (32%), Positives = 95/188 (51%), Gaps = 15/188 (7%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 N++ LL GA CL E+GY T+ RD+A AA V++A+I YHFGS++ALL+ AL W Sbjct 3 NKESLLAGAKRCLYEKGYARTTVRDLASAANVSMAAIGYHFGSREALLNAALIEANEEWG 62 Query 67 QRVQEAF--DHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 + + + + PA + + + ++SF + R E+ A E +R +LA Sbjct 63 ETLAKTLQVETPPDTSPAERFELIWQRVIESFGEHRRMWAVSFEACAQPDLDEQVRAQLA 122 Query 125 AGYADVRQHSVDLAGAALA----GTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 ++V+LA LA G D E + +V A++ G+M+QW+ DP P Sbjct 123 --------NAVELARHGLANLFQGLDDGSAEARAA-GTVHQALLSGVMLQWLIDPDHAPS 173 Query 181 STEVIRAL 188 ++ L Sbjct 174 GADLASGL 181 >gi|254383226|ref|ZP_04998579.1| TetR-family transcriptional regulator [Streptomyces sp. Mg1] gi|194342124|gb|EDX23090.1| TetR-family transcriptional regulator [Streptomyces sp. Mg1] Length=194 Score = 82.4 bits (202), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 58/199 (30%), Positives = 92/199 (47%), Gaps = 37/199 (18%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL E+G+ T++RDI +A+G N+ASI YH+GSKDALL A W Sbjct 3 HREDLLEGAKKCLVEKGFVRTTARDIVKASGANLASIGYHYGSKDALLTQAFTELMEEWG 62 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIR------------PAVYACVESYAPAL 114 + + D G G +++ F Q+ P A +E Sbjct 63 EVFKTGVD-----GEGG--------SLERFRQVWDGVLSQHAAGAGPVWAASMEVALSGD 109 Query 115 RSEALRERLAAGYADVRQHSVDLAGAALAGTDIAPPENLS-----TIVSVLMAVIDGLMI 169 R LR LA + R+ + A G P E ++ T+ + A+++GL+I Sbjct 110 RLPELRTLLAGSQGEGRRGLI----AMFTGR---PEEGITEREVRTLGAFYQALLNGLVI 162 Query 170 QWIADPSATPRSTEVIRAL 188 QW+ DP + + E+ + Sbjct 163 QWLFDPESAATAEELTDGM 181 >gi|226973360|gb|ACO94493.1| TetR-type transcriptional regulator [Streptomyces sp. MP39-85] Length=198 Score = 82.4 bits (202), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 52/187 (28%), Positives = 92/187 (50%), Gaps = 6/187 (3%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL GA CL E+GY T++RDI A+G N+ASI YH+G+K+ALL+ A+ W Sbjct 3 HREDLLAGAKQCLYEKGYARTTARDIVEASGANLASIGYHYGTKEALLNAAIMEAAEEWV 62 Query 67 QRVQEAFDH--SRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLA 124 Q ++ A P + V ++ F++ RP A ++ + +R A Sbjct 63 QELKGALADVADLPEDPIKRFETVWTRVIELFDRHRPVWGAQFDAISQRDHVPEVRRFFA 122 Query 125 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 ++ V L G++++ PE + + A++ G+M+QW+ +P + Sbjct 123 EAQQQAQKGLVQL---LWDGSELS-PEAEAAVGQFYHALLSGVMMQWVVNPEHASTGESL 178 Query 185 IRALASI 191 AL ++ Sbjct 179 AEALRTV 185 >gi|302530329|ref|ZP_07282671.1| predicted protein [Streptomyces sp. AA4] gi|302439224|gb|EFL11040.1| predicted protein [Streptomyces sp. AA4] Length=191 Score = 78.6 bits (192), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 55/190 (29%), Positives = 97/190 (52%), Gaps = 12/190 (6%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALL----DDALGRCF 62 NR+ LL+ A CLRERG +T++RDIA AGV++A+I YHFG+KDALL +A+G Sbjct 6 NREDLLEAARVCLRERGL-STTARDIASEAGVSLAAIGYHFGTKDALLAQAATEAIGDAL 64 Query 63 STWNQRVQEAFDHSRAAGPAGQILAVLEATV-DSFEQIRPAVYACVESYAPALRSEALRE 121 W ++ + A G+ A + ++F ++P + +E +R+ + Sbjct 65 GAW---IENTLRETPAGADPGRTFAEFCGRLPEAFASVQPHLLTSLEHLTRLVRTGDPQT 121 Query 122 RLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRS 181 +A +RQ + LA A P + + + AV++G + W+A P + P + Sbjct 122 TMAPA---MRQSTDALAKILGAVHPQLSPSEVDGLAQLYHAVLNGASLIWLAAPDSAPTA 178 Query 182 TEVIRALASI 191 + A++++ Sbjct 179 DQFQHAVSAL 188 >gi|289770803|ref|ZP_06530181.1| regulatory protein [Streptomyces lividans TK24] gi|289701002|gb|EFD68431.1| regulatory protein [Streptomyces lividans TK24] Length=197 Score = 76.3 bits (186), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/187 (34%), Positives = 92/187 (50%), Gaps = 8/187 (4%) Query 17 ACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFD-- 74 A R++G+ + RDIA A+GV++A+I YHFGS++ALL AL W R+ Sbjct 15 AAWRKKGWARITVRDIAAASGVSVAAIGYHFGSREALLTSALIEAIDEWGTRLGRTLSAY 74 Query 75 HSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHS 134 S A A A+ A + SF + R A +E+ A S+ LR LA G A R+ Sbjct 75 GSEGASAAEHYEALGAAVIGSFTEDRTLWLATLEALVQAEHSDDLRRYLATGQAQGRRGL 134 Query 135 VDLAGAALAGT--DIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIRALASIG 192 L L GT D + S +A+ GLM QW+ DP PR+ E + L ++ Sbjct 135 AAL----LRGTSEDDIDDATARSPGSTQLALFTGLMTQWLTDPDQAPRAPEGVSGLRALT 190 Query 193 AVVTSQL 199 +V S++ Sbjct 191 HLVRSEV 197 >gi|295836359|ref|ZP_06823292.1| TetR-family transcriptional regulator [Streptomyces sp. SPB74] gi|295825981|gb|EFG64593.1| TetR-family transcriptional regulator [Streptomyces sp. SPB74] Length=206 Score = 75.5 bits (184), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 58/190 (31%), Positives = 84/190 (45%), Gaps = 39/190 (20%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL ++G+ T++RDI R +G N+ASI YH+GSKDALL A N Sbjct 3 HREDLLEGAKRCLMDKGFAATTARDIVRESGANLASIGYHYGSKDALLGQAYVALVEEMN 62 Query 67 QRVQEAFDHSRAA-GPAGQILAVLEATVDSFEQIR----------------PAVYACVES 109 + + AA G A EA + F R P +A + + Sbjct 63 LDAPPKWPGAGAAPGSLAHFRARWEAILGEFPAQRALWRLSFEMALFGDRWPDAHAVLVA 122 Query 110 YAPALRSEALRERLAAGYADVRQHSVDLAGAALAG--TDIAPPENLSTIVSVLMAVIDGL 167 PA RS L AA G D PPE + T + + +++GL Sbjct 123 AQPAGRSGLL--------------------AAFTGLDEDTLPPELVDTEGRLYLTLLNGL 162 Query 168 MIQWIADPSA 177 +QW+ DP + Sbjct 163 TLQWLFDPGS 172 >gi|345009538|ref|YP_004811892.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344035887|gb|AEM81612.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=237 Score = 74.7 bits (182), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 56/196 (29%), Positives = 92/196 (47%), Gaps = 18/196 (9%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL GA C+ E+G+ T++RDI A+G N+ASI YH+GSKDAL+ +AL W Sbjct 11 HREDLLVGAKRCIEEKGWSRTTARDIVAASGANLASIGYHYGSKDALMREALFAAMGDWA 70 Query 67 QRVQEAFDHSRAAGPAG-----QILAVLEA----TVDSFEQIRPAVYACVESYAPALRSE 117 VQ + + A PAG ++ E ++ F + + + +E+ Sbjct 71 DDVQRSLE---ADAPAGDDQDTELRERFETRWTRVLELFGKHQAMWQSQLEAILQVRHDP 127 Query 118 ALRERLAAGYADVRQHSVDLAGAALAGTD--IAPPENLSTIVSVLMAVIDGLMIQWIADP 175 LR + RQ V L + G D E + S M ++ G+++Q DP Sbjct 128 ELRAAFGRAQPEGRQGLVGL----IHGIDERDVDEETSRVMGSFYMTLVSGMVVQMAIDP 183 Query 176 SATPRSTEVIRALASI 191 P + +++ A+ I Sbjct 184 DLMPSAHDLVEAMRRI 199 >gi|302554338|ref|ZP_07306680.1| transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302471956|gb|EFL35049.1| transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=192 Score = 74.7 bits (182), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 55/197 (28%), Positives = 89/197 (46%), Gaps = 26/197 (13%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL +G+ T++RDI + +G N+ASI YH+GSKDALL A + Sbjct 3 HREDLLEGAKRCLLAKGFVRTTARDIVKESGTNLASIGYHYGSKDALLAQA----YVDMV 58 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAG 126 + + AF+ G L +++ F ++ + A + R + Sbjct 59 EGMSGAFE-------GGGELTGEPGSLERFAEVWANIIATMREPGSMWRLSMEIVAMGDQ 111 Query 127 YADVRQHSVDLAGAALAG------------TDIAPPENLSTIVSVLMAVIDGLMIQWIAD 174 +VR+H LA A G D P E + T+ + V+ GLM QW D Sbjct 112 LPEVREH---LARAQREGARGIVTLFHGGNEDEIPEERVDTLGYFYLTVMMGLMAQWTFD 168 Query 175 PSATPRSTEVIRALASI 191 P + P + ++ L + Sbjct 169 PKSAPEAGQLAEGLRQV 185 >gi|254385526|ref|ZP_05000852.1| regulatory protein [Streptomyces sp. Mg1] gi|194344397|gb|EDX25363.1| regulatory protein [Streptomyces sp. Mg1] Length=200 Score = 74.3 bits (181), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 65/197 (33%), Positives = 95/197 (49%), Gaps = 16/197 (8%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ LL GA CL E+GY T+ RDIA A+ V++A+I YHFGS+DALL+ AL W Sbjct 14 NREDLLAGARRCLEEKGYLRTTVRDIAAASNVSMAAIGYHFGSRDALLNLALSAAMDEW- 72 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVD----SFEQIRPAVYACVESYAPALRSEALRER 122 A R AG T D F ++R A VE++ A S L Sbjct 73 -----AAGSGRLAGEGDTAEERYADTWDRKIRDFGEMRWLWTASVEAFVHAQSSPELLAP 127 Query 123 LAAGYADVRQHSVDLAGAALAG--TDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR 180 LA R+ + A L G D E++ + S +A++ G+M+Q + DP P Sbjct 128 LAENQRQARR----MVAAQLRGVPVDAVAEEDVRALGSFHIALLSGVMVQALTDPGQAPT 183 Query 181 STEVIRALASIGAVVTS 197 E+ + L ++ ++ S Sbjct 184 GRELAQGLRAMAELLES 200 >gi|331694261|ref|YP_004330500.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190] gi|326948950|gb|AEA22647.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190] Length=195 Score = 73.9 bits (180), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 70/190 (37%), Positives = 93/190 (49%), Gaps = 15/190 (7%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGR----CF 62 +RD+LL GA CL ++G+ TS+RD+ A+G N+ASI YHFGSKDALL AL C Sbjct 3 HRDELLAGARECLHDKGWSRTSARDVVAASGTNLASIGYHFGSKDALLAAALVAMTRDCA 62 Query 63 STWNQRVQEAFDHSRAAGPAGQILAVLEAT----VDSFEQIRPAVYACVESYAPALRSEA 118 + + + EA A PA L E T VD Q V A VE+ A A R Sbjct 63 AAVDAALTEAVTEESPA-PAPTPLDRFERTWDRVVDRVAQDERMVTATVEALAQAPRVPE 121 Query 119 LRERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSAT 178 +R+ LAA R+ DLA A D L L+ G ++QW DP++ Sbjct 122 VRDALAAAADLTRE---DLALTFHADEDDGRTRALGAFYQALLI---GTLVQWAVDPASA 175 Query 179 PRSTEVIRAL 188 P ++ AL Sbjct 176 PSGRDLADAL 185 >gi|333989892|ref|YP_004522506.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333485860|gb|AEF35252.1| transcriptional regulator TetR family protein [Mycobacterium sp. JDM601] Length=167 Score = 73.9 bits (180), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 66/185 (36%), Positives = 92/185 (50%), Gaps = 28/185 (15%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 NR+ LL GA CL ERG+ +T+ RDIA AAGV+ A+I YHFGS++ LL AL + Sbjct 3 NREDLLQGAKRCLVERGWASTTVRDIAAAAGVSHAAIGYHFGSRERLLIQALLEEMDELD 62 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAG 126 R+ D S +A Q L +DSF R + +E+ A R++ LR RLA G Sbjct 63 TRLTPQ-DRSASAVDRWQPL------IDSFTTDRALWTSHLEAIVHAQRNDELRTRLAEG 115 Query 127 YADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIR 186 A R T SV +A++ GLMIQ + +P + P + EV+ Sbjct 116 QARART---------------------ETGGSVALAIVLGLMIQSLINPDSAPTAGEVLA 154 Query 187 ALASI 191 L + Sbjct 155 ELRDL 159 >gi|271965220|ref|YP_003339416.1| TetR family transcriptional regulator [Streptosporangium roseum DSM 43021] gi|270508395|gb|ACZ86673.1| putative transcriptional regulator, TetR family [Streptosporangium roseum DSM 43021] Length=178 Score = 72.8 bits (177), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/192 (34%), Positives = 91/192 (48%), Gaps = 26/192 (13%) Query 9 DKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQR 68 + LL A CL ERGY T+ RDI +G N+A+INYHF SKDALL A+ Sbjct 5 EDLLAAAKQCLSERGYARTTVRDIVAVSGSNLAAINYHFRSKDALLTQAMIEVTGEAVAE 64 Query 69 VQEAF-DHSRAAGPAGQILAVLEATVDSFEQIRPAVY-ACVESYAPALRSEALRERLAAG 126 V +AF D ++ A ++SF + P V+ A VE+ A A +R RLA G Sbjct 65 VLKAFPDDAKE-----WFEAFWAELIESF-RANPTVWRANVETLAQAPHLPEVRARLAEG 118 Query 127 YADVRQHSVDLAGAALAGTDIAP--PENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEV 184 ALA ++A P VL+ + GL+++W DP P + ++ Sbjct 119 Q-------------ALAQRELAQRLPRQDEAGAQVLLTLFIGLLVRWQIDPDNAPTAHDL 165 Query 185 ---IRALASIGA 193 IR++A A Sbjct 166 AAGIRSVAEAAA 177 >gi|297202560|ref|ZP_06919957.1| transcriptional regulator [Streptomyces sviceus ATCC 29083] gi|197709913|gb|EDY53947.1| transcriptional regulator [Streptomyces sviceus ATCC 29083] Length=193 Score = 72.8 bits (177), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 59/205 (29%), Positives = 94/205 (46%), Gaps = 29/205 (14%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL E+G+ T++RDI + +G N+ASI YH+GSKDALL A + + Sbjct 3 HREDLLEGAKRCLLEKGFARTTARDIVKESGTNLASIGYHYGSKDALLAQA----YVSLV 58 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAG 126 + + +AF+ G L +++ F+++ V A + P E + G Sbjct 59 EGMSDAFEGD------GTALTAEPGSLERFQEVWSNVVATMRE--PGSIWHLSMEIVVMG 110 Query 127 --YADVRQHSVDLAGAAL-AGTDIAP-----------PENLSTIVSVLMAVIDGLMIQWI 172 +VR H LA A AG + P E T+ + ++ GL+ QW Sbjct 111 DQLPEVRDH---LARAQREAGRGLVPMLMGGREEDVSDETADTLGMFYVTLMTGLIAQWT 167 Query 173 ADPSATPRSTEVIRALASIGAVVTS 197 DP P ++ L + A T Sbjct 168 FDPKTAPTGEQLTEGLRQVIAGTTK 192 >gi|297156948|gb|ADI06660.1| putative transcriptional regulator, TetR family protein [Streptomyces bingchenggensis BCW-1] Length=212 Score = 71.6 bits (174), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 58/202 (29%), Positives = 89/202 (45%), Gaps = 19/202 (9%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL GA CL E+G+ T++RDI A+G N+ASI YH+GSKDAL+ +AL W Sbjct 3 HREDLLAGAKRCLLEKGWSRTTARDIVAASGANLASIGYHYGSKDALMREALFAAMGEWA 62 Query 67 QRVQEAFDHS--RAAGPAGQI-----------LAVLEA----TVDSFEQIRPAVYACVES 109 V+ + GP +A E ++ F + + A +E+ Sbjct 63 DDVERSLREEVRSPEGPGAAAGSAAEGSEAGQVARFEVGWTRMLELFGKHQALWRAQLEA 122 Query 110 YAPALRSEALRERLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMI 169 A LR + R+ V L L D E+ + S M ++ G+ + Sbjct 123 VMRAEGDPELRAAFGQAQPEGRKGLVALFHGIL--EDEVDEESARILGSFYMTLVGGMAV 180 Query 170 QWIADPSATPRSTEVIRALASI 191 Q DP TP + E+ A+ I Sbjct 181 QMAIDPDGTPGAGELTEAMRRI 202 >gi|297191883|ref|ZP_06909281.1| transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] gi|197721141|gb|EDY65049.1| transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] Length=195 Score = 70.9 bits (172), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 53/194 (28%), Positives = 92/194 (48%), Gaps = 24/194 (12%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL +G+ T++RDI + +G N+ASI YH+GSKDALL +A + Sbjct 3 HREDLLEGAKRCLLAKGFVRTTARDIVKESGTNLASIGYHYGSKDALLAEA----YVGLV 58 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSE--------- 117 + V + FD + + + D F+++ + A + R Sbjct 59 EGVSDHFDATEES-----TTGTRPGSTDRFQEVWRNIIATMSGPDSLWRLSMEIVVMGDQ 113 Query 118 --ALRERLAAGYADVRQHSVDLAGAALAGTDIAPPE-NLSTIVSVLMAVIDGLMIQWIAD 174 A+R+ LAA R+ + + + G + E ++ T+ M ++ GL+ QW D Sbjct 114 LPAVRDHLAAAQ---REGARGIIPMFMGGEEADVAEGDVDTLGKFYMTLMMGLIAQWTFD 170 Query 175 PSATPRSTEVIRAL 188 P+ R+ E+ L Sbjct 171 PATATRAEELAEGL 184 >gi|294631553|ref|ZP_06710113.1| TetR-family transcriptional regulator [Streptomyces sp. e14] gi|292834886|gb|EFF93235.1| TetR-family transcriptional regulator [Streptomyces sp. e14] Length=225 Score = 70.1 bits (170), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 57/204 (28%), Positives = 94/204 (47%), Gaps = 22/204 (10%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL +G+ T++RDI + +G N+ASI YH+GSKDALL +A + + Sbjct 3 HREDLLEGAKRCLLAKGFLRTTARDIVKESGTNLASIGYHYGSKDALLVEA----YISLV 58 Query 67 QRVQEAFDHSRAA-GPAGQILAVLE-------ATVDSFEQIRPAVYACVESYAPALRSEA 118 Q + + + A G +G LE + + S + R E R Sbjct 59 QEMGDGYGPDWGADGGSGTRAGSLERFQEVWASIIRSVPESRAIWMISFELIFQGDRMPE 118 Query 119 LRERLAAGYADVRQHSVDLAGAALAGTDIAP----PENLSTIVSVLMAVIDGLMIQWIAD 174 +R+ LA + R V L TD+ + + T + ++ GLM+QW+ D Sbjct 119 VRKLLAQAQEEGRSGIVPLF------TDVPEADLDKDTVDTEGRLYQTLLQGLMVQWLFD 172 Query 175 PSATPRSTEVIRALASIGAVVTSQ 198 P + ++ L + A VT + Sbjct 173 PGTATHADQLTEGLRRVIAGVTGK 196 >gi|329936825|ref|ZP_08286504.1| transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329303750|gb|EGG47634.1| transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=200 Score = 69.7 bits (169), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 55/180 (31%), Positives = 86/180 (48%), Gaps = 14/180 (7%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL +G+ T++RDI + +G N+ASI YH+GSKDALL A + Sbjct 3 HREDLLEGAKRCLLAKGFAATTARDIVKESGTNLASIGYHYGSKDALLAQA----YVALV 58 Query 67 QRVQEAFDHSR---AAGPAGQI---LAVLEATVDSFEQIRPAVYACVESYAPALRSEALR 120 V +AF+ S A P G + AV + + + +E A R A+R Sbjct 59 GEVSDAFEGSERLLADTPPGSLERFEAVWSNIIATMREPGSMWRLSIEIVAMGDRLPAVR 118 Query 121 ERLAAGYADVRQHSVDLAGAALAG-TDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATP 179 E LA + + V L + G + P E + T+ ++ GL+ + DP + P Sbjct 119 EHLAKAQREAMRALVPL---FMGGQEEQVPEETVDTLGGFYYTLMMGLITHYNFDPDSAP 175 >gi|226940528|ref|YP_002795602.1| transcriptional regulator, TetR family [Laribacter hongkongensis HLHK9] gi|226715455|gb|ACO74593.1| Probable transcriptional regulator, TetR family [Laribacter hongkongensis HLHK9] Length=232 Score = 67.8 bits (164), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 40/94 (43%), Positives = 56/94 (60%), Gaps = 6/94 (6%) Query 10 KLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRV 69 ++LD A E G+ TS R I + A VN+A++NYHFGSKDALL A+ R + WN+R Sbjct 27 RILDVAERLFVEHGFEATSLRMITQQAEVNLAAVNYHFGSKDALLQQAVIRRLAPWNRRC 86 Query 70 QEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAV 103 E D A +G++L V E V F +RP++ Sbjct 87 IEELD---ALEVSGEVLTV-ENLVQGF--VRPSL 114 >gi|302558212|ref|ZP_07310554.1| transcriptional regulator [Streptomyces griseoflavus Tu4000] gi|302475830|gb|EFL38923.1| transcriptional regulator [Streptomyces griseoflavus Tu4000] Length=196 Score = 66.6 bits (161), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 56/187 (30%), Positives = 85/187 (46%), Gaps = 29/187 (15%) Query 7 NRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWN 66 +R+ LL+GA CL +G+ T++RDI R +G N+ASI YH+GSKDALL A Sbjct 3 HREDLLEGAKRCLLAKGFVRTTARDIVRESGTNLASIGYHYGSKDALLAQAYVSLIEGMG 62 Query 67 QRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAG 126 + + AA +++ FE++ + A + R E LA G Sbjct 63 GAFEGGGNVDEAA----------PGSLERFERVWSNIIATMRDPGTVWRLSM--EVLALG 110 Query 127 --YADVRQHSVDLAGAAL-AGTDIAP-----------PENLSTIVSVLMAVIDGLMIQWI 172 +VR H LA A AG + P E T+ + + ++ GL+ QW Sbjct 111 DRLPEVRDH---LAKAQREAGRGLVPLLMGGREEDVSDETADTLGAFYVTLMTGLIAQWT 167 Query 173 ADPSATP 179 DP++ P Sbjct 168 FDPASAP 174 >gi|319779268|ref|YP_004130181.1| transcriptional regulator,TetR family [Taylorella equigenitalis MCE9] gi|317109292|gb|ADU92038.1| transcriptional regulator,TetR family [Taylorella equigenitalis MCE9] Length=228 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/75 (47%), Positives = 47/75 (63%), Gaps = 2/75 (2%) Query 8 RDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQ 67 R ++L+ A + E+GY + S RDI + AGVN+AS+NYHFGSKDAL+ L R N+ Sbjct 13 RRQILNAAEKLIVEKGYESASMRDITQLAGVNLASVNYHFGSKDALIAAVLKRRLGAINK 72 Query 68 RVQEAFD--HSRAAG 80 E D +RAAG Sbjct 73 ERLEKLDALEARAAG 87 >gi|296131736|ref|YP_003638983.1| transcriptional regulator, TetR family [Thermincola sp. JR] gi|296030314|gb|ADG81082.1| transcriptional regulator, TetR family [Thermincola potens JR] Length=180 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 54/191 (29%), Positives = 89/191 (47%), Gaps = 25/191 (13%) Query 6 TNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDAL----LDDALGRC 61 NR+K++ A E+G + DIAR AG+ ++ Y++ SK++L LD +G Sbjct 3 NNREKIIMAARKAFAEKGIHRATLGDIAREAGIAKGTLYYYYKSKESLVFEVLDHGIGVL 62 Query 62 FSTWNQRVQEAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRE 121 + + + E D AG +LEA + E + + ES+ R+ ALRE Sbjct 63 LNGFGG-INEETD------LAGLTRGLLEAMTANTELLHIYFHLLQESF----RNPALRE 111 Query 122 RLAAGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSA-TPR 180 R Y + R+ + PE LST+ +A++DGL +QW+ +P A P+ Sbjct 112 RFRHKYREWREWGT----VVFRQCKLGDPEELSTL---FIAILDGLCLQWLVEPEAVNPK 164 Query 181 STEVIRALASI 191 + ALA + Sbjct 165 KISL--ALAKL 173 Lambda K H 0.319 0.131 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 218250040016 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40