BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0359
Length=259
Score E
Sequences producing significant alignments: (Bits) Value
gi|15607500|ref|NP_214873.1| integral membrane protein [Mycobact... 502 2e-140
gi|31791536|ref|NP_854029.1| integral membrane protein [Mycobact... 500 7e-140
gi|254363325|ref|ZP_04979371.1| conserved integral membrane prot... 499 1e-139
gi|340625389|ref|YP_004743841.1| putative integral membrane prot... 498 2e-139
gi|15839745|ref|NP_334782.1| hypothetical protein MT0375 [Mycoba... 414 7e-114
gi|289748843|ref|ZP_06508221.1| conserved membrane protein [Myco... 393 1e-107
gi|183980703|ref|YP_001848994.1| hypothetical protein MMAR_0678 ... 379 3e-103
gi|118618261|ref|YP_906593.1| hypothetical protein MUL_2836 [Myc... 375 5e-102
gi|240173048|ref|ZP_04751706.1| hypothetical protein MkanA1_2729... 366 2e-99
gi|254822876|ref|ZP_05227877.1| peptidase, M50 family protein [M... 360 9e-98
gi|342859133|ref|ZP_08715787.1| hypothetical protein MCOL_09653 ... 352 3e-95
gi|118472331|ref|YP_885163.1| peptidase, M50B family protein [My... 345 4e-93
gi|118466371|ref|YP_883908.1| peptidase, M50 family protein [Myc... 342 3e-92
gi|296167842|ref|ZP_06850026.1| M50B family peptidase [Mycobacte... 342 4e-92
gi|336460394|gb|EGO39294.1| Zn-dependent protease [Mycobacterium... 339 3e-91
gi|41409964|ref|NP_962800.1| hypothetical protein MAP3866c [Myco... 339 3e-91
gi|120401689|ref|YP_951518.1| peptidase M50 [Mycobacterium vanba... 333 1e-89
gi|145220835|ref|YP_001131513.1| peptidase M50 [Mycobacterium gi... 329 3e-88
gi|315442211|ref|YP_004075090.1| Zn-dependent protease [Mycobact... 328 4e-88
gi|108797487|ref|YP_637684.1| peptidase M50 [Mycobacterium sp. M... 327 9e-88
gi|169631329|ref|YP_001704978.1| hypothetical protein MAB_4251 [... 296 1e-78
gi|333989001|ref|YP_004521615.1| hypothetical protein JDM601_036... 294 1e-77
gi|312141288|ref|YP_004008624.1| metallopeptidase [Rhodococcus e... 271 8e-71
gi|325673878|ref|ZP_08153568.1| M50B family peptidase [Rhodococc... 271 8e-71
gi|226304915|ref|YP_002764873.1| hypothetical protein RER_14260 ... 253 2e-65
gi|229492985|ref|ZP_04386780.1| peptidase M50 [Rhodococcus eryth... 253 3e-65
gi|226365028|ref|YP_002782811.1| peptidase M50 family protein [R... 248 5e-64
gi|289756425|ref|ZP_06515803.1| LOW QUALITY PROTEIN: integral me... 248 6e-64
gi|111022515|ref|YP_705487.1| hypothetical protein RHA1_ro05549 ... 248 6e-64
gi|317507048|ref|ZP_07964812.1| peptidase family M50 [Segnilipar... 231 7e-59
gi|262203907|ref|YP_003275115.1| peptidase M50 [Gordonia bronchi... 225 5e-57
gi|54027349|ref|YP_121591.1| putative peptidase [Nocardia farcin... 224 8e-57
gi|296394182|ref|YP_003659066.1| peptidase M50 [Segniliparus rot... 216 4e-54
gi|326384111|ref|ZP_08205794.1| peptidase M50 [Gordonia neofelif... 200 2e-49
gi|134102898|ref|YP_001108559.1| peptidase M50 [Saccharopolyspor... 193 2e-47
gi|291008017|ref|ZP_06565990.1| peptidase M50 [Saccharopolyspora... 193 2e-47
gi|269128103|ref|YP_003301473.1| peptidase M50 [Thermomonospora ... 189 3e-46
gi|159039083|ref|YP_001538336.1| peptidase M50 [Salinispora aren... 185 7e-45
gi|329934902|ref|ZP_08284943.1| membrane protein [Streptomyces g... 183 2e-44
gi|145595826|ref|YP_001160123.1| peptidase M50 [Salinispora trop... 182 3e-44
gi|291440021|ref|ZP_06579411.1| membrane protein [Streptomyces g... 182 4e-44
gi|254386853|ref|ZP_05002141.1| membrane protein [Streptomyces s... 182 5e-44
gi|302550966|ref|ZP_07303308.1| membrane protein [Streptomyces v... 180 2e-43
gi|302560974|ref|ZP_07313316.1| membrane protein [Streptomyces g... 177 2e-42
gi|320011125|gb|ADW05975.1| peptidase M50 [Streptomyces flavogri... 176 4e-42
gi|294629020|ref|ZP_06707580.1| membrane protein [Streptomyces s... 175 6e-42
gi|330469399|ref|YP_004407142.1| peptidase M50 [Verrucosispora m... 175 6e-42
gi|29832480|ref|NP_827114.1| hypothetical protein SAV_5937 [Stre... 175 7e-42
gi|238060340|ref|ZP_04605049.1| peptidase M50 [Micromonospora sp... 174 8e-42
gi|311895766|dbj|BAJ28174.1| putative peptidase M50 family prote... 174 1e-41
>gi|15607500|ref|NP_214873.1| integral membrane protein [Mycobacterium tuberculosis H37Rv]
gi|148660125|ref|YP_001281648.1| putative integral membrane protein [Mycobacterium tuberculosis
H37Ra]
gi|148821555|ref|YP_001286309.1| integral membrane protein [Mycobacterium tuberculosis F11]
51 more sequence titles
Length=259
Score = 502 bits (1293), Expect = 2e-140, Method: Compositional matrix adjust.
Identities = 258/259 (99%), Positives = 259/259 (100%), Gaps = 0/259 (0%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH
Sbjct 1 MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL
Sbjct 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
Query 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV
Sbjct 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
Query 241 SHRLAAAGSVLARFWSIWF 259
SHRLAAAGSVLARFWSIWF
Sbjct 241 SHRLAAAGSVLARFWSIWF 259
>gi|31791536|ref|NP_854029.1| integral membrane protein [Mycobacterium bovis AF2122/97]
gi|121636272|ref|YP_976495.1| putative integral membrane protein [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224988744|ref|YP_002643431.1| putative integral membrane protein [Mycobacterium bovis BCG str.
Tokyo 172]
16 more sequence titles
Length=259
Score = 500 bits (1288), Expect = 7e-140, Method: Compositional matrix adjust.
Identities = 257/259 (99%), Positives = 258/259 (99%), Gaps = 0/259 (0%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH
Sbjct 1 MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL
Sbjct 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
Query 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV
Sbjct 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
Query 241 SHRLAAAGSVLARFWSIWF 259
SHRLAAAGSVL RFWSIWF
Sbjct 241 SHRLAAAGSVLTRFWSIWF 259
>gi|254363325|ref|ZP_04979371.1| conserved integral membrane protein [Mycobacterium tuberculosis
str. Haarlem]
gi|134148839|gb|EBA40884.1| conserved integral membrane protein [Mycobacterium tuberculosis
str. Haarlem]
Length=259
Score = 499 bits (1286), Expect = 1e-139, Method: Compositional matrix adjust.
Identities = 257/259 (99%), Positives = 258/259 (99%), Gaps = 0/259 (0%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH
Sbjct 1 MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL
Sbjct 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
Query 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
PIPGLDGYAALEPHLRPETQRALAPAKQFALVF LVLFLAPTLNGWFFGVVYWLFDLSGV
Sbjct 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFRLVLFLAPTLNGWFFGVVYWLFDLSGV 240
Query 241 SHRLAAAGSVLARFWSIWF 259
SHRLAAAGSVLARFWSIWF
Sbjct 241 SHRLAAAGSVLARFWSIWF 259
>gi|340625389|ref|YP_004743841.1| putative integral membrane protein [Mycobacterium canettii CIPT
140010059]
gi|340003579|emb|CCC42700.1| putative conserved integral membrane protein [Mycobacterium canettii
CIPT 140010059]
Length=259
Score = 498 bits (1283), Expect = 2e-139, Method: Compositional matrix adjust.
Identities = 256/259 (99%), Positives = 257/259 (99%), Gaps = 0/259 (0%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH
Sbjct 1 MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
FMTTARRTLVSLAGPTVNLALAMLLL ATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL
Sbjct 121 FMTTARRTLVSLAGPTVNLALAMLLLTATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
Query 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV
Sbjct 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
Query 241 SHRLAAAGSVLARFWSIWF 259
SHRLAAAGSVL RFWSIWF
Sbjct 241 SHRLAAAGSVLTRFWSIWF 259
>gi|15839745|ref|NP_334782.1| hypothetical protein MT0375 [Mycobacterium tuberculosis CDC1551]
gi|13879872|gb|AAK44596.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
Length=212
Score = 414 bits (1064), Expect = 7e-114, Method: Compositional matrix adjust.
Identities = 212/212 (100%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 48 MVIAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGG 107
MVIAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGG
Sbjct 1 MVIAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGG 60
Query 108 IGLPGAAVYVHTWFMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFL 167
IGLPGAAVYVHTWFMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFL
Sbjct 61 IGLPGAAVYVHTWFMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFL 120
Query 168 AFLQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWF 227
AFLQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWF
Sbjct 121 AFLQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWF 180
Query 228 FGVVYWLFDLSGVSHRLAAAGSVLARFWSIWF 259
FGVVYWLFDLSGVSHRLAAAGSVLARFWSIWF
Sbjct 181 FGVVYWLFDLSGVSHRLAAAGSVLARFWSIWF 212
>gi|289748843|ref|ZP_06508221.1| conserved membrane protein [Mycobacterium tuberculosis T92]
gi|289689430|gb|EFD56859.1| conserved membrane protein [Mycobacterium tuberculosis T92]
Length=337
Score = 393 bits (1009), Expect = 1e-107, Method: Compositional matrix adjust.
Identities = 236/253 (94%), Positives = 238/253 (95%), Gaps = 4/253 (1%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH
Sbjct 1 MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL
Sbjct 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
Query 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFG W S V
Sbjct 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFG---WCTGSSTV 237
Query 241 SHRLAAAGSVLAR 253
R+A AG R
Sbjct 238 -WRVAPAGRRGQR 249
>gi|183980703|ref|YP_001848994.1| hypothetical protein MMAR_0678 [Mycobacterium marinum M]
gi|183174029|gb|ACC39139.1| conserved hypothetical membrane protein [Mycobacterium marinum
M]
Length=256
Score = 379 bits (972), Expect = 3e-103, Method: Compositional matrix adjust.
Identities = 199/254 (79%), Positives = 212/254 (84%), Gaps = 0/254 (0%)
Query 5 GQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGH 64
G ESVRPSPIFLGL+GLT VG ALAWLAG +V+PLAYAGVFV VIAGWLVSLCLHEFGH
Sbjct 2 GLHESVRPSPIFLGLVGLTTVGAALAWLAGSSVRPLAYAGVFVFVIAGWLVSLCLHEFGH 61
Query 65 AFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTT 124
AFTAWRFGDHDVAVRGYLTLDPRRYSHP LSL LPM+FIALGGIGLPGAAVYV TWFMT
Sbjct 62 AFTAWRFGDHDVAVRGYLTLDPRRYSHPALSLLLPMVFIALGGIGLPGAAVYVRTWFMTP 121
Query 125 ARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPG 184
RRTLVSLAGP N+ LA+LLL ATRL +D H VLWAGVAFL FLQ+ A+VLNLLPIPG
Sbjct 122 TRRTLVSLAGPAANVVLAVLLLTATRLFYDQDHWVLWAGVAFLGFLQIMAVVLNLLPIPG 181
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGY ALEPHL P+TQRALAPAKQF + LL L LAP LN W F V W+FD SGV H L
Sbjct 182 LDGYDALEPHLSPQTQRALAPAKQFGIFILLFLLLAPVLNQWLFEFVGWVFDFSGVPHLL 241
Query 245 AAAGSVLARFWSIW 258
A G+ L RFWS W
Sbjct 242 AMVGNSLTRFWSQW 255
>gi|118618261|ref|YP_906593.1| hypothetical protein MUL_2836 [Mycobacterium ulcerans Agy99]
gi|118570371|gb|ABL05122.1| conserved hypothetical membrane protein [Mycobacterium ulcerans
Agy99]
Length=259
Score = 375 bits (962), Expect = 5e-102, Method: Compositional matrix adjust.
Identities = 197/258 (77%), Positives = 211/258 (82%), Gaps = 0/258 (0%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SE G ESVRPSPIFLGL+GLT VG ALAWL G +V+PLAYAGVFV IAGWLVSLCLH
Sbjct 1 MSEMGLHESVRPSPIFLGLVGLTTVGAALAWLTGSSVRPLAYAGVFVFAIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHP LSL LPM+FIALGGIGLPGAAVYV TW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPALSLLLPMVFIALGGIGLPGAAVYVRTW 120
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLL 180
FMT RRTLVSLAGP N+ LA+LLL ATRL +D H VLWAGVAFL FLQ+ A+VL LL
Sbjct 121 FMTPTRRTLVSLAGPAANVVLAVLLLTATRLFYDQDHWVLWAGVAFLGFLQIMAVVLKLL 180
Query 181 PIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGV 240
PIPGLDGY ALEPHL P+TQRALAPAKQF + LL L LAP LN W F V W+ D SGV
Sbjct 181 PIPGLDGYDALEPHLSPQTQRALAPAKQFGIFILLFLLLAPVLNQWLFEFVGWVSDFSGV 240
Query 241 SHRLAAAGSVLARFWSIW 258
H LA G+ L RFWS W
Sbjct 241 PHLLAMVGNSLTRFWSQW 258
>gi|240173048|ref|ZP_04751706.1| hypothetical protein MkanA1_27296 [Mycobacterium kansasii ATCC
12478]
Length=256
Score = 366 bits (939), Expect = 2e-99, Method: Compositional matrix adjust.
Identities = 202/254 (80%), Positives = 216/254 (86%), Gaps = 0/254 (0%)
Query 5 GQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGH 64
G ESVRPSPIFLGL+ LTAVGGALAWLAG +V+PLAYAGVF VIAGWLVSLCLHEFGH
Sbjct 2 GLHESVRPSPIFLGLVALTAVGGALAWLAGASVRPLAYAGVFTFVIAGWLVSLCLHEFGH 61
Query 65 AFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTT 124
AFTAWRFGDHD AVRGYLTLDPRRYSHP +SL LPM+FIALGGIGLPGAAVY+ TWFMT
Sbjct 62 AFTAWRFGDHDTAVRGYLTLDPRRYSHPAMSLLLPMVFIALGGIGLPGAAVYLRTWFMTP 121
Query 125 ARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPG 184
RR+LVSLAGP NLALA+LLLAATRL +D H VLWAGVAFL FLQ+ ALVLNLLPIPG
Sbjct 122 TRRSLVSLAGPAANLALAVLLLAATRLFYDEHHWVLWAGVAFLGFLQIMALVLNLLPIPG 181
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGY ALEPHL PETQRALAPAKQF + LL + LAP LN W FG+V WLFD SGV H L
Sbjct 182 LDGYDALEPHLSPETQRALAPAKQFGIFILLFVLLAPVLNQWLFGLVGWLFDFSGVPHVL 241
Query 245 AAAGSVLARFWSIW 258
A AG+ L RFWS W
Sbjct 242 AGAGNSLTRFWSRW 255
>gi|254822876|ref|ZP_05227877.1| peptidase, M50 family protein [Mycobacterium intracellulare ATCC
13950]
Length=260
Score = 360 bits (925), Expect = 9e-98, Method: Compositional matrix adjust.
Identities = 198/254 (78%), Positives = 210/254 (83%), Gaps = 0/254 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
QRESVRPSPIFL LLGLTAVGG LAW AG + +PLAY GVF+ VIAGWLVSLCLHEFGHA
Sbjct 7 QRESVRPSPIFLALLGLTAVGGGLAWQAGYSARPLAYVGVFIFVIAGWLVSLCLHEFGHA 66
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TAWRFGDHD AVRGYLTLDPRRY+HP LSL LP++ +ALGGIGLPGAAVYV TWFMT A
Sbjct 67 VTAWRFGDHDAAVRGYLTLDPRRYAHPALSLVLPLVIVALGGIGLPGAAVYVRTWFMTPA 126
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGL 185
RRTLVSLAGP NL LA LLLA RL FDP H VLWA VAFL FLQLTA+VLNLLPIPGL
Sbjct 127 RRTLVSLAGPAANLVLAALLLALIRLFFDPTHVVLWAAVAFLGFLQLTAVVLNLLPIPGL 186
Query 186 DGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLA 245
DGY ALEPHL PETQRALAPAKQ+ V LL L LAP LN WFFG+V LFDLSGV L
Sbjct 187 DGYDALEPHLNPETQRALAPAKQWGFVILLFLLLAPVLNHWFFGIVLSLFDLSGVPDVLV 246
Query 246 AAGSVLARFWSIWF 259
+ G+ L RFWS WF
Sbjct 247 SWGNGLTRFWSRWF 260
>gi|342859133|ref|ZP_08715787.1| hypothetical protein MCOL_09653 [Mycobacterium colombiense CECT
3035]
gi|342133374|gb|EGT86577.1| hypothetical protein MCOL_09653 [Mycobacterium colombiense CECT
3035]
Length=260
Score = 352 bits (903), Expect = 3e-95, Method: Compositional matrix adjust.
Identities = 199/256 (78%), Positives = 212/256 (83%), Gaps = 0/256 (0%)
Query 4 TGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFG 63
+ +RESVRPSPIFLGL+ LT VG ALAW AG + +PLAYAGVFV VIAGWLVSLCLHEFG
Sbjct 5 SSRRESVRPSPIFLGLIALTGVGAALAWSAGISTRPLAYAGVFVFVIAGWLVSLCLHEFG 64
Query 64 HAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMT 123
HA TAWRFGDHD AVRGYLTLDPRRY+HP LSL LPM+ I LGGIGLPGAAVYV TWFMT
Sbjct 65 HAVTAWRFGDHDDAVRGYLTLDPRRYAHPGLSLALPMVVILLGGIGLPGAAVYVRTWFMT 124
Query 124 TARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIP 183
ARRT+VSLAGP NL LA LLLAATRL FDP H VLW+GVAFLAFLQLTA++LNLLPIP
Sbjct 125 PARRTMVSLAGPAANLVLAALLLAATRLFFDPAHVVLWSGVAFLAFLQLTAVLLNLLPIP 184
Query 184 GLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHR 243
GLDGY ALEPHL PETQRALAPAKQ+ V LL L LAP LN WFFGVV LFD SGV
Sbjct 185 GLDGYDALEPHLSPETQRALAPAKQWGFVILLFLLLAPVLNHWFFGVVLSLFDASGVPDV 244
Query 244 LAAAGSVLARFWSIWF 259
L G+ L RFWS WF
Sbjct 245 LVGWGNALTRFWSRWF 260
>gi|118472331|ref|YP_885163.1| peptidase, M50B family protein [Mycobacterium smegmatis str.
MC2 155]
gi|118173618|gb|ABK74514.1| peptidase, M50B family protein [Mycobacterium smegmatis str.
MC2 155]
Length=259
Score = 345 bits (885), Expect = 4e-93, Method: Compositional matrix adjust.
Identities = 174/253 (69%), Positives = 208/253 (83%), Gaps = 0/253 (0%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
R+SVRPSPIFL ++ +TA GGALAW+A +T++PL+Y GVF++VIAGWL+SLCLHEFGHAF
Sbjct 7 RQSVRPSPIFLLVIAVTAAGGALAWIAADTIRPLSYVGVFILVIAGWLMSLCLHEFGHAF 66
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTAR 126
TAWRFGDH V RGYLTL+P +Y+HPMLSLGLP+L IALGGIG PG AVY+ T +MT +
Sbjct 67 TAWRFGDHGVETRGYLTLNPLKYTHPMLSLGLPVLIIALGGIGFPGGAVYLQTHWMTARQ 126
Query 127 RTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLD 186
+++VSLAGP NL LA+LLL TR +DP HAV W+G+AFL FLQ+TALVLNLLPIPGLD
Sbjct 127 KSIVSLAGPAANLVLAVLLLGLTRAFWDPAHAVFWSGIAFLGFLQVTALVLNLLPIPGLD 186
Query 187 GYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAA 246
GY ALEPHL PETQRALAPAKQ+ + ++VL + P LN WFF +VYW FD SGVS L +
Sbjct 187 GYGALEPHLNPETQRALAPAKQWGFLIVVVLLITPALNRWFFELVYWFFDFSGVSSYLVS 246
Query 247 AGSVLARFWSIWF 259
AG L RFWS WF
Sbjct 247 AGGQLTRFWSAWF 259
>gi|118466371|ref|YP_883908.1| peptidase, M50 family protein [Mycobacterium avium 104]
gi|118167658|gb|ABK68555.1| peptidase, M50 family protein [Mycobacterium avium 104]
Length=260
Score = 342 bits (877), Expect = 3e-92, Method: Compositional matrix adjust.
Identities = 202/253 (80%), Positives = 212/253 (84%), Gaps = 0/253 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
Q ESVRPSPIFL LLGLTA+GGALAWLAG + +PLAY GVFV VIAGWLVSLCLHEFGHA
Sbjct 7 QHESVRPSPIFLALLGLTALGGALAWLAGSSPRPLAYLGVFVFVIAGWLVSLCLHEFGHA 66
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TAWRFGD D AVRGYLTLDPRRYSHP LSL LPM+ IALGGIGLPGAAVYV TWFMT A
Sbjct 67 VTAWRFGDRDAAVRGYLTLDPRRYSHPALSLVLPMVIIALGGIGLPGAAVYVQTWFMTPA 126
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGL 185
RRTLVSLAGP NL LA +LLA TR F HAVLWAGVAFL FLQLTA++LNLLPIPGL
Sbjct 127 RRTLVSLAGPAANLVLAAVLLALTRAFFTADHAVLWAGVAFLGFLQLTAVLLNLLPIPGL 186
Query 186 DGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLA 245
DGY ALEPHL PETQRALAPAKQ+ LL L LAP LN WFFG+VYWLFD SGV H LA
Sbjct 187 DGYDALEPHLSPETQRALAPAKQWGFFILLFLLLAPGLNRWFFGIVYWLFDFSGVPHWLA 246
Query 246 AAGSVLARFWSIW 258
AG+VL RFWS W
Sbjct 247 GAGNVLTRFWSRW 259
>gi|296167842|ref|ZP_06850026.1| M50B family peptidase [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295897013|gb|EFG76635.1| M50B family peptidase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=257
Score = 342 bits (876), Expect = 4e-92, Method: Compositional matrix adjust.
Identities = 194/254 (77%), Positives = 212/254 (84%), Gaps = 2/254 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+RESVRPSP+FL L+GLTAVGGALAW AG TV+PLAY GVF VIAGWLVSLCLHEFGHA
Sbjct 6 RRESVRPSPLFLALVGLTAVGGALAWQAGSTVRPLAYFGVFTFVIAGWLVSLCLHEFGHA 65
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TAWRFGDHD AVRGYLTLDPRRYSHP LSL LPM+ IALGGIGLPGAAVYV TWFMT
Sbjct 66 VTAWRFGDHDAAVRGYLTLDPRRYSHPALSLLLPMVVIALGGIGLPGAAVYVRTWFMTPN 125
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGL 185
RRTLVSLAGP NL LA+LLLA TRLL+DP H VLWAGVAFL FLQLTA+VLN+LPIPGL
Sbjct 126 RRTLVSLAGPAANLVLAVLLLALTRLLYDPFHQVLWAGVAFLGFLQLTAVVLNVLPIPGL 185
Query 186 DGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLA 245
DGY ALEPHL PETQRA+APAKQ+ LL L L + WFFG++ WLF+ SGV L
Sbjct 186 DGYDALEPHLSPETQRAVAPAKQWGFFILLFLLL--PASHWFFGMMLWLFEFSGVQPWLV 243
Query 246 AAGSVLARFWSIWF 259
+AG++L RFWS WF
Sbjct 244 SAGNLLTRFWSRWF 257
>gi|336460394|gb|EGO39294.1| Zn-dependent protease [Mycobacterium avium subsp. paratuberculosis
S397]
Length=260
Score = 339 bits (869), Expect = 3e-91, Method: Compositional matrix adjust.
Identities = 200/253 (80%), Positives = 210/253 (84%), Gaps = 0/253 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
Q ESVRPSPIFL LLGLTA+GGALAWL G + +PLAY GVFV VIAGWLVSLCLHEFGHA
Sbjct 7 QHESVRPSPIFLALLGLTALGGALAWLTGSSPRPLAYLGVFVFVIAGWLVSLCLHEFGHA 66
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
AWRFGD D AVRGYLTLDPRRYSHP LSL LPM+ IALGGIGLPGAAVYV TWFMT A
Sbjct 67 VIAWRFGDRDAAVRGYLTLDPRRYSHPALSLVLPMVIIALGGIGLPGAAVYVQTWFMTPA 126
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGL 185
RRTLVSLAGP NL LA +LLA TR F HAVLWAGVAFL FLQLTA++LNLLPIPGL
Sbjct 127 RRTLVSLAGPAANLVLAAVLLALTRAFFTADHAVLWAGVAFLGFLQLTAVLLNLLPIPGL 186
Query 186 DGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLA 245
DGY ALEPHL PETQRALAPAKQ+ LL L LAP LN WFFG+VYWLFD SGV H LA
Sbjct 187 DGYDALEPHLSPETQRALAPAKQWGFFILLFLLLAPGLNRWFFGIVYWLFDFSGVPHWLA 246
Query 246 AAGSVLARFWSIW 258
AG+VL RFWS W
Sbjct 247 GAGNVLTRFWSRW 259
>gi|41409964|ref|NP_962800.1| hypothetical protein MAP3866c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398797|gb|AAS06416.1| hypothetical protein MAP_3866c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=260
Score = 339 bits (869), Expect = 3e-91, Method: Compositional matrix adjust.
Identities = 200/253 (80%), Positives = 210/253 (84%), Gaps = 0/253 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
Q ESVRPSPIFL LLGLTA+GGALAWL G + +PLAY GVFV VIAGWLVSLCLHEFGHA
Sbjct 7 QHESVRPSPIFLALLGLTALGGALAWLTGSSPRPLAYLGVFVFVIAGWLVSLCLHEFGHA 66
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
AWRFGD D AVRGYLTLDPRRYSHP LSL LPM+ IALGGIGLPGAAVYV TWFMT A
Sbjct 67 VIAWRFGDRDAAVRGYLTLDPRRYSHPALSLVLPMVIIALGGIGLPGAAVYVQTWFMTPA 126
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGL 185
RRTLVSLAGP NL LA +LLA TR F HAVLWAGVAFL FLQLTA++LNLLPIPGL
Sbjct 127 RRTLVSLAGPAANLVLAAVLLALTRAFFTADHAVLWAGVAFLGFLQLTAVLLNLLPIPGL 186
Query 186 DGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLA 245
DGY ALEPHL PETQRALAPAKQ+ LL L LAP LN WFFG+VYWLFD SGV H LA
Sbjct 187 DGYDALEPHLSPETQRALAPAKQWGFFTLLFLLLAPGLNRWFFGIVYWLFDFSGVPHWLA 246
Query 246 AAGSVLARFWSIW 258
AG+VL RFWS W
Sbjct 247 GAGNVLTRFWSRW 259
>gi|120401689|ref|YP_951518.1| peptidase M50 [Mycobacterium vanbaalenii PYR-1]
gi|119954507|gb|ABM11512.1| peptidase M50 [Mycobacterium vanbaalenii PYR-1]
Length=259
Score = 333 bits (854), Expect = 1e-89, Method: Compositional matrix adjust.
Identities = 178/252 (71%), Positives = 207/252 (83%), Gaps = 0/252 (0%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
+SVRPSPIFL L+ +TA GGALAW + ++P+AY GVFV VI GWLV+LCLHEFGHA+
Sbjct 7 HQSVRPSPIFLALVAVTAAGGALAWTSAGRIEPVAYIGVFVFVIFGWLVTLCLHEFGHAY 66
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTAR 126
+A+RFGD DVAVRGYLTL+P +YSHP+LSLGLP+LFIALGGIGLPG AVYV T MT +
Sbjct 67 SAYRFGDRDVAVRGYLTLNPLKYSHPLLSLGLPVLFIALGGIGLPGGAVYVQTAHMTDRQ 126
Query 127 RTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLD 186
+TLVSLAGP VNL A+LLLA TRLL+DP H+V WAGVAFL FLQ+TAL+LN+LPIPGLD
Sbjct 127 KTLVSLAGPGVNLIFAVLLLALTRLLYDPAHSVFWAGVAFLGFLQVTALLLNMLPIPGLD 186
Query 187 GYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAA 246
GY ALEPHL P+TQRAL PAKQ+ LL+L +AP LN WFFG VYWLF+LSGV L+A
Sbjct 187 GYGALEPHLSPDTQRALNPAKQWGFFILLILLIAPPLNQWFFGAVYWLFELSGVPPALSA 246
Query 247 AGSVLARFWSIW 258
G L RFWS W
Sbjct 247 IGGQLTRFWSAW 258
>gi|145220835|ref|YP_001131513.1| peptidase M50 [Mycobacterium gilvum PYR-GCK]
gi|145213321|gb|ABP42725.1| peptidase M50 [Mycobacterium gilvum PYR-GCK]
Length=256
Score = 329 bits (843), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 171/249 (69%), Positives = 203/249 (82%), Gaps = 0/249 (0%)
Query 10 VRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAFTAW 69
VRPSP+F L+ +TA GGALAW +G+ V+PL+YA VFV+VI GWLV+LCLHEFGHA++A+
Sbjct 7 VRPSPVFAALVAVTAAGGALAWTSGDDVRPLSYAAVFVLVIFGWLVTLCLHEFGHAYSAY 66
Query 70 RFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTARRTL 129
RFGD DVAVRGYLTL+P +Y+HP+LSLGLP+LFIALGGIGLPG AVYV T MT ++T+
Sbjct 67 RFGDRDVAVRGYLTLNPLKYTHPLLSLGLPVLFIALGGIGLPGGAVYVQTALMTDRQKTV 126
Query 130 VSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLDGYA 189
VSLAGP VNL A+LLL TR ++DP HAV WAGVAFL FLQ+TA VLN+LPIPGLDGY
Sbjct 127 VSLAGPAVNLLFAVLLLGLTRPMYDPAHAVFWAGVAFLGFLQVTAFVLNMLPIPGLDGYG 186
Query 190 ALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAAAGS 249
ALEPHL PET+RALAPA+Q+ LL+L +AP LN WFF VYWLF+LSGV L+ G
Sbjct 187 ALEPHLSPETRRALAPARQWGFFILLILLIAPPLNQWFFAAVYWLFELSGVDVYLSQLGG 246
Query 250 VLARFWSIW 258
L RFWS W
Sbjct 247 GLTRFWSPW 255
>gi|315442211|ref|YP_004075090.1| Zn-dependent protease [Mycobacterium sp. Spyr1]
gi|315260514|gb|ADT97255.1| Zn-dependent protease [Mycobacterium sp. Spyr1]
Length=256
Score = 328 bits (841), Expect = 4e-88, Method: Compositional matrix adjust.
Identities = 172/249 (70%), Positives = 205/249 (83%), Gaps = 0/249 (0%)
Query 10 VRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAFTAW 69
VRPSP+F L+ +TA GGALAW +G+ V+PL+YA VFV+VI GWLV+LCLHEFGHA++A+
Sbjct 7 VRPSPVFAALVAVTAAGGALAWTSGDDVRPLSYAAVFVLVIFGWLVTLCLHEFGHAYSAY 66
Query 70 RFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTARRTL 129
RFGD DVAVRGYLTL+P +Y+HP+LSLGLP+LFIALGG+GLPG AVYV T MT ++T+
Sbjct 67 RFGDRDVAVRGYLTLNPLKYTHPLLSLGLPVLFIALGGVGLPGGAVYVQTALMTDRQKTV 126
Query 130 VSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLDGYA 189
VSLAGP VNL A+LLLA TRL++DP HAV WAGVAFLAFLQ+TA VLN+LPIPGLDGY
Sbjct 127 VSLAGPAVNLLFAVLLLALTRLMYDPAHAVFWAGVAFLAFLQVTAFVLNMLPIPGLDGYG 186
Query 190 ALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAAAGS 249
ALEPHL PET+RALA A+Q+ LL+L +AP LN WFF VYWLF+LSGV L+ G
Sbjct 187 ALEPHLSPETRRALALARQWGFFILLILLIAPPLNQWFFAAVYWLFELSGVDVYLSQLGG 246
Query 250 VLARFWSIW 258
L RFWS W
Sbjct 247 GLTRFWSPW 255
>gi|108797487|ref|YP_637684.1| peptidase M50 [Mycobacterium sp. MCS]
gi|119866572|ref|YP_936524.1| peptidase M50 [Mycobacterium sp. KMS]
gi|126433108|ref|YP_001068799.1| peptidase M50 [Mycobacterium sp. JLS]
gi|108767906|gb|ABG06628.1| peptidase M50 [Mycobacterium sp. MCS]
gi|119692661|gb|ABL89734.1| peptidase M50 [Mycobacterium sp. KMS]
gi|126232908|gb|ABN96308.1| peptidase M50 [Mycobacterium sp. JLS]
Length=259
Score = 327 bits (839), Expect = 9e-88, Method: Compositional matrix adjust.
Identities = 176/252 (70%), Positives = 207/252 (83%), Gaps = 0/252 (0%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
R+SVRPSP+FL ++ +T GGALAW+A +TV PLAYAGVFV+VIAGWLVSL LHEFGHA+
Sbjct 7 RQSVRPSPVFLAVVAITVAGGALAWMAADTVAPLAYAGVFVLVIAGWLVSLSLHEFGHAY 66
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTAR 126
TA+RFGD DV +RGYLTL+P +YSHPMLSLGLP+LFIALGGIGLPG AVY+ T +MT +
Sbjct 67 TAFRFGDRDVEIRGYLTLNPLKYSHPMLSLGLPVLFIALGGIGLPGGAVYLRTSWMTARQ 126
Query 127 RTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLD 186
+TLVSLAGP+ NL LA+LLL +TRLL+DP H V WAG+AFL FLQ+TA VLN+LP+PGLD
Sbjct 127 KTLVSLAGPSANLVLAVLLLGSTRLLYDPAHGVFWAGLAFLGFLQVTAFVLNMLPVPGLD 186
Query 187 GYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAA 246
GY ALEPHL P+TQRAL P KQ+ LL+L LAP LN WFFG VYWL +LSGV L +
Sbjct 187 GYGALEPHLSPDTQRALVPVKQWGFFILLILLLAPALNQWFFGAVYWLAELSGVPSALMS 246
Query 247 AGSVLARFWSIW 258
G L RFWS W
Sbjct 247 IGGQLTRFWSAW 258
>gi|169631329|ref|YP_001704978.1| hypothetical protein MAB_4251 [Mycobacterium abscessus ATCC 19977]
gi|169243296|emb|CAM64324.1| Conserved hypothetical protein (peptidase?) [Mycobacterium abscessus]
Length=254
Score = 296 bits (759), Expect = 1e-78, Method: Compositional matrix adjust.
Identities = 151/250 (61%), Positives = 181/250 (73%), Gaps = 2/250 (0%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
++SVRPSP+FL L+ LT G AWL G++ +PLA GVFV V AGW+VSLCLHEFGHA+
Sbjct 4 KQSVRPSPVFLVLVALTVAGAVFAWLGGDSTEPLARGGVFVFVFAGWIVSLCLHEFGHAY 63
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTAR 126
TAWRFGD RGYLTL+P +Y+ P+LS+ LP++FIALGGIGLPG AVYVHT MT +
Sbjct 64 TAWRFGDTQA--RGYLTLNPLQYTDPVLSIALPLVFIALGGIGLPGGAVYVHTAGMTNRQ 121
Query 127 RTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLD 186
RT+VSLAGPT N LA+L+L T L D H V WA +A+L FLQ+TA+VLNLLP+PGLD
Sbjct 122 RTIVSLAGPTANAILAVLILGTTALFADREHVVFWAAMAYLGFLQVTAVVLNLLPVPGLD 181
Query 187 GYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAA 246
GY ALEPHL P TQR L AK F + L L ++P +N FFG VYW+ GV LA
Sbjct 182 GYGALEPHLSPNTQRTLGNAKTFGFLILFALLMSPPVNRAFFGAVYWIVAYLGVDPALAQ 241
Query 247 AGSVLARFWS 256
G L RFWS
Sbjct 242 IGGWLFRFWS 251
>gi|333989001|ref|YP_004521615.1| hypothetical protein JDM601_0361 [Mycobacterium sp. JDM601]
gi|333484969|gb|AEF34361.1| integral membrane protein [Mycobacterium sp. JDM601]
Length=261
Score = 294 bits (752), Expect = 1e-77, Method: Compositional matrix adjust.
Identities = 165/253 (66%), Positives = 196/253 (78%), Gaps = 1/253 (0%)
Query 8 ESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAFT 67
++VRPSP+FL L+ +TA+GG LAW A + P+AYAGVFV VIAGWLVSLCLHEFGHAFT
Sbjct 9 QAVRPSPVFLALVAVTALGGVLAWRAAGEIGPMAYAGVFVFVIAGWLVSLCLHEFGHAFT 68
Query 68 AWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTARR 127
AWRFGD +RGYLTL+P RY+HP LSL LP+LFIALGGIGLPG AVYV T FMT RR
Sbjct 69 AWRFGDRGAEMRGYLTLNPLRYTHPGLSLVLPLLFIALGGIGLPGGAVYVQTSFMTPLRR 128
Query 128 TLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLDG 187
+LVSLAGP NL LA LLL ATR+ +DP H V ++G+AFL FLQ+TA++LNLLP+PGLDG
Sbjct 129 SLVSLAGPAANLVLAGLLLGATRVCYDPAHPVFFSGLAFLGFLQVTAVLLNLLPVPGLDG 188
Query 188 YAALEPHLRPETQRALAPAKQFALVFLLVLFL-APTLNGWFFGVVYWLFDLSGVSHRLAA 246
Y ALEPHL P TQRA+AP Q+ L+ LLVL + +P LN FFG+V W DL V L +
Sbjct 189 YGALEPHLSPATQRAVAPFSQWGLLVLLVLLISSPMLNQKFFGLVLWFVDLFAVPRLLVS 248
Query 247 AGSVLARFWSIWF 259
G L +FW+ WF
Sbjct 249 WGMSLTQFWNSWF 261
>gi|312141288|ref|YP_004008624.1| metallopeptidase [Rhodococcus equi 103S]
gi|311890627|emb|CBH49945.1| putative secreted metallopeptidase [Rhodococcus equi 103S]
Length=259
Score = 271 bits (693), Expect = 8e-71, Method: Compositional matrix adjust.
Identities = 145/256 (57%), Positives = 182/256 (72%), Gaps = 3/256 (1%)
Query 2 SETGQRES-VRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
S+ R S VRPSP+FLG++ + AVGG LAW A + GVF++V+AGW+V+LCLH
Sbjct 3 SDARPRASLVRPSPVFLGIVAIAAVGGVLAWRATGN-EMSGRIGVFLLVVAGWVVTLCLH 61
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EF HAF AWR GDHDV +RGYLTLDPR+Y+ P+LS+GLP++F+ALGGIGLPG AVY+ T
Sbjct 62 EFAHAFVAWRNGDHDVVMRGYLTLDPRKYTQPLLSIGLPVVFLALGGIGLPGGAVYLQTG 121
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLL-FDPIHAVLWAGVAFLAFLQLTALVLNL 179
M +T VSLAGP VN A++LLA RL D H V W G++FLAFLQ+ A VLNL
Sbjct 122 LMPPRTQTRVSLAGPAVNAVAAIVLLAVIRLFGLDGDHQVFWWGLSFLAFLQVMATVLNL 181
Query 180 LPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSG 239
LP+PGLDGY ALEPHL+P T+ +L K F L+ L+ L P +N FF +YWLF+LSG
Sbjct 182 LPVPGLDGYGALEPHLQPSTRASLDKVKPFGLLLLIALLFVPQINTVFFDAIYWLFELSG 241
Query 240 VSHRLAAAGSVLARFW 255
V A G+ L +FW
Sbjct 242 VPDVFAMFGNYLMQFW 257
>gi|325673878|ref|ZP_08153568.1| M50B family peptidase [Rhodococcus equi ATCC 33707]
gi|325555143|gb|EGD24815.1| M50B family peptidase [Rhodococcus equi ATCC 33707]
Length=259
Score = 271 bits (692), Expect = 8e-71, Method: Compositional matrix adjust.
Identities = 145/256 (57%), Positives = 182/256 (72%), Gaps = 3/256 (1%)
Query 2 SETGQRES-VRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
S+ R S VRPSP+FLG++ + AVGG LAW A + GVF++V+AGW+V+LCLH
Sbjct 3 SDARPRASLVRPSPVFLGIVAIAAVGGVLAWRATGN-EMSGRIGVFLLVVAGWVVTLCLH 61
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EF HAF AWR GDHDV +RGYLTLDPR+Y+ P+LS+GLP++F+ALGGIGLPG AVY+ T
Sbjct 62 EFAHAFVAWRNGDHDVVMRGYLTLDPRKYTQPLLSIGLPVVFLALGGIGLPGGAVYLQTG 121
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRLL-FDPIHAVLWAGVAFLAFLQLTALVLNL 179
M +T VSLAGP VN A++LLA RL D H V W G++FLAFLQ+ A VLNL
Sbjct 122 LMPPRTQTRVSLAGPAVNAVAAIVLLAVIRLFGLDGDHQVFWWGLSFLAFLQVMATVLNL 181
Query 180 LPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSG 239
LP+PGLDGY ALEPHL+P T+ +L K F L+ L+ L P +N FF +YWLF+LSG
Sbjct 182 LPVPGLDGYGALEPHLQPSTRVSLDKVKPFGLLLLIALLFVPQINTVFFDAIYWLFELSG 241
Query 240 VSHRLAAAGSVLARFW 255
V A G+ L +FW
Sbjct 242 VPDVFAMFGNYLMQFW 257
>gi|226304915|ref|YP_002764873.1| hypothetical protein RER_14260 [Rhodococcus erythropolis PR4]
gi|226184030|dbj|BAH32134.1| conserved hypothetical membrane protein [Rhodococcus erythropolis
PR4]
Length=256
Score = 253 bits (647), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 136/252 (54%), Positives = 173/252 (69%), Gaps = 4/252 (1%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLA-YAGVFVMVIAGWLVSLCLHEFGHA 65
R +VRPSP+FLG++ +T + G +AW T +A AGVFV+V+AGW+V+LCLHEF HA
Sbjct 7 RSAVRPSPVFLGVVAITVIAGVVAW--NSTWGSIAGRAGVFVLVVAGWVVTLCLHEFAHA 64
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
+ AWR GD DV RGYLTL+P +YSHPMLS+GLP+LFIALGGIGLPG AVY+ T
Sbjct 65 YLAWRHGDTDVEARGYLTLNPLKYSHPMLSIGLPVLFIALGGIGLPGGAVYLRTGMFPPK 124
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPI-HAVLWAGVAFLAFLQLTALVLNLLPIPG 184
+ +SLAGP N A++LL R H WAG++FLAFLQ+ A VLNLLP+PG
Sbjct 125 VQARISLAGPFTNAVAAVILLVVIRTYGSSAEHLTFWAGLSFLAFLQVMATVLNLLPVPG 184
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGY ALEP+L P T+ L K + L+ L+ L P +N FF +YW+F+LSGVS
Sbjct 185 LDGYNALEPYLAPNTRHQLDQFKPYGLLLLVALLFVPQINVVFFDAIYWIFELSGVSDYY 244
Query 245 AAAGSVLARFWS 256
A G+ L RFW+
Sbjct 245 AMLGNALMRFWT 256
>gi|229492985|ref|ZP_04386780.1| peptidase M50 [Rhodococcus erythropolis SK121]
gi|229320015|gb|EEN85841.1| peptidase M50 [Rhodococcus erythropolis SK121]
Length=256
Score = 253 bits (645), Expect = 3e-65, Method: Compositional matrix adjust.
Identities = 136/252 (54%), Positives = 173/252 (69%), Gaps = 4/252 (1%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLA-YAGVFVMVIAGWLVSLCLHEFGHA 65
R +VRPSP+FLG++ +T + G +AW T +A AGVFV+V+AGW+V+LCLHEF HA
Sbjct 7 RSAVRPSPVFLGVVAITVIAGIVAW--NSTWGSIAGRAGVFVLVVAGWVVTLCLHEFAHA 64
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
+ AWR GD DV RGYLTL+P +YSHPMLS+GLP+LFIALGGIGLPG AVY+ T
Sbjct 65 YLAWRHGDTDVEARGYLTLNPLKYSHPMLSIGLPVLFIALGGIGLPGGAVYLRTGMFPPK 124
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPI-HAVLWAGVAFLAFLQLTALVLNLLPIPG 184
+ +SLAGP N A++LL R H WAG++FLAFLQ+ A VLNLLP+PG
Sbjct 125 VQARISLAGPFTNAVAAVILLVVIRTYGSSAEHLTFWAGLSFLAFLQVMATVLNLLPVPG 184
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGY ALEP+L P T+ L K + L+ L+ L P +N FF +YW+F+LSGVS
Sbjct 185 LDGYNALEPYLAPNTRHQLDQFKPYGLLLLVALLFVPQINVVFFDAIYWIFELSGVSDYY 244
Query 245 AAAGSVLARFWS 256
A G+ L RFW+
Sbjct 245 AMLGNALMRFWT 256
>gi|226365028|ref|YP_002782811.1| peptidase M50 family protein [Rhodococcus opacus B4]
gi|226243518|dbj|BAH53866.1| peptidase M50 family protein [Rhodococcus opacus B4]
Length=257
Score = 248 bits (634), Expect = 5e-64, Method: Compositional matrix adjust.
Identities = 139/251 (56%), Positives = 176/251 (71%), Gaps = 2/251 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+ +VRPSP+FL ++ + GG LAW A E L + GVF++V+AGW+V+LCLHEF HA
Sbjct 7 RTTAVRPSPVFLLVVAVAVAGGVLAWRA-ERESVLGHVGVFLLVVAGWVVTLCLHEFAHA 65
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
+TAWR GD DV VRGYLTL+P +YSHP+LS+GLP+LFIALGGIGLPG AVY+ T
Sbjct 66 YTAWRHGDTDVEVRGYLTLNPLKYSHPLLSIGLPVLFIALGGIGLPGGAVYLRTGLFPPK 125
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLL-FDPIHAVLWAGVAFLAFLQLTALVLNLLPIPG 184
+ VSLAGP VNL A++LLA R H V W G++FLAFLQ+ A VLNLLP+PG
Sbjct 126 VQARVSLAGPAVNLVSAIVLLAVIRWFGLGGDHLVFWTGLSFLAFLQVMATVLNLLPVPG 185
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGYAALEP L P T+R++ K + L+ L+ L P++N FF +Y LF+LSGV
Sbjct 186 LDGYAALEPFLPPRTRRSVDQFKPYGLLILVALLFVPSINVVFFDFIYRLFELSGVPEIY 245
Query 245 AAAGSVLARFW 255
A G+ L RFW
Sbjct 246 AQYGNYLMRFW 256
>gi|289756425|ref|ZP_06515803.1| LOW QUALITY PROTEIN: integral membrane protein [Mycobacterium
tuberculosis T85]
gi|289711989|gb|EFD76001.1| LOW QUALITY PROTEIN: integral membrane protein [Mycobacterium
tuberculosis T85]
Length=260
Score = 248 bits (633), Expect = 6e-64, Method: Compositional matrix adjust.
Identities = 123/125 (99%), Positives = 124/125 (99%), Gaps = 0/125 (0%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH
Sbjct 1 MSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW
Sbjct 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
Query 121 FMTTA 125
FMTT
Sbjct 121 FMTTG 125
>gi|111022515|ref|YP_705487.1| hypothetical protein RHA1_ro05549 [Rhodococcus jostii RHA1]
gi|110822045|gb|ABG97329.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=257
Score = 248 bits (633), Expect = 6e-64, Method: Compositional matrix adjust.
Identities = 139/251 (56%), Positives = 177/251 (71%), Gaps = 2/251 (0%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+ +VRPSP+FL ++ + GG LAW A E L + GVF++V+AGW+V+LCLHEF HA
Sbjct 7 RTTAVRPSPVFLLVVAVAVAGGVLAWRA-ELESVLGHVGVFLLVVAGWVVTLCLHEFAHA 65
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
+TA R GD DV VRGYLTL+P +YSHP+LS+GLP+LFIALGGIGLPG AVY+ T +
Sbjct 66 YTARRHGDTDVEVRGYLTLNPLKYSHPLLSIGLPVLFIALGGIGLPGGAVYLRTGLFSPK 125
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLL-FDPIHAVLWAGVAFLAFLQLTALVLNLLPIPG 184
+ VSLAGP VNL A++LLA R H V W G++FLAFLQ+ A VLNLLP+PG
Sbjct 126 VQARVSLAGPAVNLVSAIVLLAVIRWFGLGGDHQVFWTGLSFLAFLQVMATVLNLLPVPG 185
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGYAALEP L P T+R++ K + L+ L+ L P++N FF V+Y LF+LSGV
Sbjct 186 LDGYAALEPFLPPRTRRSVDQFKPYGLLILVALLFVPSINVVFFDVIYRLFELSGVPEIY 245
Query 245 AAAGSVLARFW 255
A G+ L RFW
Sbjct 246 AQYGNYLMRFW 256
>gi|317507048|ref|ZP_07964812.1| peptidase family M50 [Segniliparus rugosus ATCC BAA-974]
gi|316254651|gb|EFV13957.1| peptidase family M50 [Segniliparus rugosus ATCC BAA-974]
Length=273
Score = 231 bits (590), Expect = 7e-59, Method: Compositional matrix adjust.
Identities = 138/274 (51%), Positives = 174/274 (64%), Gaps = 19/274 (6%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+S T + +RPSP+F GLLG TA+GGALAW+ GE L G FV + GWL +LCLH
Sbjct 1 MSYTSAFKGIRPSPVFFGLLGATALGGALAWV-GEPGGALGRLGAFVFIFGGWLTTLCLH 59
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHAF AWRFGDHDVA++GYL LD RRY+ P+ SL +PM+ I +GGIGLPGAAVY+ T
Sbjct 60 EFGHAFAAWRFGDHDVALKGYLDLDIRRYTDPLNSLVIPMVIILIGGIGLPGAAVYLDTQ 119
Query 121 FMTTARRTLVSLAGPTVNLALAMLLLAATRL-----------------LFDPIHAVLWAG 163
+M+ +RT++SLAGP NL A+LLLAA + H V WA
Sbjct 120 WMSKKQRTIISLAGPAANLIAAVLLLAAGAAGLASLTWFEWDGPGGGGVVQSGHLVFWAA 179
Query 164 VAFLAFLQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFA-LVFLLVLFLAPT 222
V FL FLQ+ A+V+NLLP+PGLDGY A+EP L ETQR L P +Q+ LV ++L L
Sbjct 180 VEFLGFLQVFAVVINLLPVPGLDGYGAIEPWLSYETQRKLYPVRQWGFLVLFMILLLPNP 239
Query 223 LNGWFFGVVYWLFDLSGVSHRLAAAGSVLARFWS 256
+ G++ +FDL G H A G LA W
Sbjct 240 IGAEIRGLILGVFDLLGGDHDFAGIGRRLAMPWQ 273
>gi|262203907|ref|YP_003275115.1| peptidase M50 [Gordonia bronchialis DSM 43247]
gi|262087254|gb|ACY23222.1| peptidase M50 [Gordonia bronchialis DSM 43247]
Length=276
Score = 225 bits (573), Expect = 5e-57, Method: Compositional matrix adjust.
Identities = 127/263 (49%), Positives = 164/263 (63%), Gaps = 17/263 (6%)
Query 8 ESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAFT 67
+VRP PIF+GL+ + +GG L A ++ G ++V++GW++SLCLHEF HA T
Sbjct 15 RAVRPGPIFVGLVAVAILGGWLCAQAEPGRNAVSVGGSLLLVLSGWVISLCLHEFAHAVT 74
Query 68 AWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTARR 127
A+RFGD + RGYLTL+P RY+H LS+ LPML I LGGIG PG AVYV+ T A+R
Sbjct 75 AFRFGDRNTETRGYLTLNPMRYTHVGLSIVLPMLIILLGGIGFPGGAVYVNQAGFTRAQR 134
Query 128 TLVSLAGPTVNLALAMLLLAATRLL---------------FDPIHAVLWAGVAFLAFLQL 172
T VSLAGP N+ L +LLA R+L D I+ LW ++ LAFLQL
Sbjct 135 TAVSLAGPLTNIVLGAILLAVVRVLGADAGYGTVGGLWVGTDGIN--LWGALSMLAFLQL 192
Query 173 TALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVY 232
TA VLNLLP+PG DGY A+EP+L +T+ A A + + L+ L P LN FF VV+
Sbjct 193 TAAVLNLLPVPGFDGYGAIEPYLSDQTRAAAAKIAPYGFLILIALLFIPVLNQAFFDVVF 252
Query 233 WLFDLSGVSHRLAAAGSVLARFW 255
W+F LSGV LA+ G L FW
Sbjct 253 WIFGLSGVPSALASYGWNLFVFW 275
>gi|54027349|ref|YP_121591.1| putative peptidase [Nocardia farcinica IFM 10152]
gi|54018857|dbj|BAD60227.1| putative peptidase [Nocardia farcinica IFM 10152]
Length=262
Score = 224 bits (572), Expect = 8e-57, Method: Compositional matrix adjust.
Identities = 130/253 (52%), Positives = 171/253 (68%), Gaps = 6/253 (2%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLA--GETVQPLAYAGVFVMVIAGWLVSLCLHEFGH 64
R +VRPSP+FL ++ +T G LAW++ GET A GVFV+V+AGW+V+LCLHEF H
Sbjct 13 RGAVRPSPVFLLVVAVTVAGAVLAWISDYGETA---AGVGVFVLVVAGWIVTLCLHEFAH 69
Query 65 AFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTT 124
A+ AWR GD +V +RGYLTL+P +YSHP+LS+ LP++FIALGG GLPG AVYVH ++
Sbjct 70 AYLAWRAGDREVELRGYLTLNPLKYSHPLLSIVLPVVFIALGGFGLPGGAVYVHPHAVSP 129
Query 125 ARRTLVSLAGPTVNLALAMLLLAATRLLFDPI-HAVLWAGVAFLAFLQLTALVLNLLPIP 183
AR+ ++S AGP VN ++LL + HA W G+AFL FLQ+TA +LNLLPIP
Sbjct 130 ARQRMISGAGPAVNAVCGVVLLLVVAVFGSTTGHAAFWYGLAFLGFLQITATLLNLLPIP 189
Query 184 GLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHR 243
GLDGY LEP L T+R+L K ++ L L L PT+N FF +Y + +L GV
Sbjct 190 GLDGYGILEPSLSYRTRRSLDQLKPLGMLLLFALILTPTVNRPFFDAIYTICELFGVPDV 249
Query 244 LAAAGSVLARFWS 256
A G+ L RFW+
Sbjct 250 WVARGAGLVRFWT 262
>gi|296394182|ref|YP_003659066.1| peptidase M50 [Segniliparus rotundus DSM 44985]
gi|296181329|gb|ADG98235.1| peptidase M50 [Segniliparus rotundus DSM 44985]
Length=275
Score = 216 bits (549), Expect = 4e-54, Method: Compositional matrix adjust.
Identities = 135/268 (51%), Positives = 169/268 (64%), Gaps = 20/268 (7%)
Query 8 ESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAFT 67
+ +RPSP+FLG+L TA+GGALAW G+ +PL+ G FV V+AGWLV+LCLHEFGHAF
Sbjct 8 QGIRPSPVFLGVLAATALGGALAWF-GDPGEPLSKLGAFVFVLAGWLVTLCLHEFGHAFA 66
Query 68 AWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTARR 127
AWRFGDHDVA++GYL LD RRY+ P+ SL +P++ I +GGIGLPGAAVY+ T +M +R
Sbjct 67 AWRFGDHDVAIKGYLDLDIRRYTDPLNSLVIPLVIILIGGIGLPGAAVYLDTQWMQKKKR 126
Query 128 TLVSLAGPTVN------------------LALAMLLLAATRLLFDPIHAVLWAGVAFLAF 169
T+VSLAGP N L L A L+F H V W V FL
Sbjct 127 TIVSLAGPGANLLAAVVLLGAGALGGGVPLFRQTLGGADGELVFGSGHLVFWGAVEFLGL 186
Query 170 LQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFG 229
LQ+ ALV+NLLPIPGLDGY A+EP L ETQR L P +Q+A + L ++ L P G
Sbjct 187 LQVFALVINLLPIPGLDGYGAIEPWLSYETQRKLYPVRQWAFLVLFLVLLMPNPLGSLIR 246
Query 230 VVYW-LFDLSGVSHRLAAAGSVLARFWS 256
+ W +F L G + LA G A W
Sbjct 247 ELVWSVFGLLGGNQLLAVLGQSFALPWQ 274
>gi|326384111|ref|ZP_08205794.1| peptidase M50 [Gordonia neofelifaecis NRRL B-59395]
gi|326197271|gb|EGD54462.1| peptidase M50 [Gordonia neofelifaecis NRRL B-59395]
Length=259
Score = 200 bits (508), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 123/254 (49%), Positives = 157/254 (62%), Gaps = 3/254 (1%)
Query 4 TGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFG 63
T +SVRP P+F+GL A+G L +G L G V V++GW++SL LHEF
Sbjct 6 TAALKSVRPGPVFVGLCAAFAIGAFLLVQSGAERSALGMFGALVFVLSGWVISLSLHEFA 65
Query 64 HAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMT 123
HAFTA+R+GD VRGYLTL+PR+Y+H LS+ LP+L +ALGGIG PG AVY++T T
Sbjct 66 HAFTAFRYGDRSPQVRGYLTLEPRKYTHAGLSIALPLLIVALGGIGFPGGAVYLNTAAFT 125
Query 124 TARRTLVSLAGPTVNLALAMLLLAATRLLFDPIHA--VLWAGVAFLAFLQLTALVLNLLP 181
A+RT VSLAGP NL L + LL A P + LWA A LAFLQL+A +LN+LP
Sbjct 126 PAQRTKVSLAGPLTNLVLGLGLLIALAST-TPTESNLNLWAATAALAFLQLSATLLNILP 184
Query 182 IPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVS 241
+PG DGY A+EPHL + + + LLVL P LN FFG+VY +FD G+S
Sbjct 185 VPGFDGYGAIEPHLPMNIRITAEKIAPYGFLILLVLLFIPALNAAFFGLVYDVFDAFGIS 244
Query 242 HRLAAAGSVLARFW 255
+ G L FW
Sbjct 245 PAFVSYGMRLFAFW 258
>gi|134102898|ref|YP_001108559.1| peptidase M50 [Saccharopolyspora erythraea NRRL 2338]
gi|133915521|emb|CAM05634.1| peptidase M50 [Saccharopolyspora erythraea NRRL 2338]
Length=248
Score = 193 bits (491), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 116/251 (47%), Positives = 153/251 (61%), Gaps = 6/251 (2%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+VR SP+FL L+ T GG LA GV ++V+ GW SLCLHEFGHA
Sbjct 2 MNSAVRVSPLFLALVAATVAGGVLATFPNTVA---ITTGVVLIVLGGWATSLCLHEFGHA 58
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TA+R GD V +GYL+LDPR Y+ P+LS+ LP+LF+A+GGI LPG AV+++ + T
Sbjct 59 LTAYRGGDLSVRSKGYLSLDPRHYTDPVLSIVLPLLFVAIGGIPLPGGAVWINHHALRTR 118
Query 126 R-RTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPG 184
R ++VSLAGP NL L + L A ++ P+ L +G+++LA+LQ+ A VLN+LPIPG
Sbjct 119 RVESMVSLAGPLTNLVLGIALTAV--VVSVPMPEGLGSGLSYLAYLQVIAFVLNILPIPG 176
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGY A+EP L + A+ +A + L L LA L G FF V Y LFD G L
Sbjct 177 LDGYGAIEPWLSGPAREFGEKARPWAPLVLFALILATPLGGLFFDVSYLLFDAVGGDAGL 236
Query 245 AAAGSVLARFW 255
A G RFW
Sbjct 237 TATGMSTFRFW 247
>gi|291008017|ref|ZP_06565990.1| peptidase M50 [Saccharopolyspora erythraea NRRL 2338]
Length=247
Score = 193 bits (490), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 116/251 (47%), Positives = 153/251 (61%), Gaps = 6/251 (2%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+VR SP+FL L+ T GG LA GV ++V+ GW SLCLHEFGHA
Sbjct 1 MNSAVRVSPLFLALVAATVAGGVLATFPNTVA---ITTGVVLIVLGGWATSLCLHEFGHA 57
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TA+R GD V +GYL+LDPR Y+ P+LS+ LP+LF+A+GGI LPG AV+++ + T
Sbjct 58 LTAYRGGDLSVRSKGYLSLDPRHYTDPVLSIVLPLLFVAIGGIPLPGGAVWINHHALRTR 117
Query 126 R-RTLVSLAGPTVNLALAMLLLAATRLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPG 184
R ++VSLAGP NL L + L A ++ P+ L +G+++LA+LQ+ A VLN+LPIPG
Sbjct 118 RVESMVSLAGPLTNLVLGIALTAV--VVSVPMPEGLGSGLSYLAYLQVIAFVLNILPIPG 175
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDGY A+EP L + A+ +A + L L LA L G FF V Y LFD G L
Sbjct 176 LDGYGAIEPWLSGPAREFGEKARPWAPLVLFALILATPLGGLFFDVSYLLFDAVGGDAGL 235
Query 245 AAAGSVLARFW 255
A G RFW
Sbjct 236 TATGMSTFRFW 246
>gi|269128103|ref|YP_003301473.1| peptidase M50 [Thermomonospora curvata DSM 43183]
gi|268313061|gb|ACY99435.1| peptidase M50 [Thermomonospora curvata DSM 43183]
Length=267
Score = 189 bits (480), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 113/246 (46%), Positives = 153/246 (63%), Gaps = 5/246 (2%)
Query 2 SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYA-GVFVMVIAGWLVSLCLH 60
+ G R +VRPSP+FL +LG T + G +AW + A +F +V+AGW++SLCLH
Sbjct 6 TAKGGRAAVRPSPVFLAILGATVIFGLMAWRYESYYEERAAQLTLFGLVLAGWILSLCLH 65
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
EFGHA+ A+R GD VA +GYLTL+P +Y LS LP+LFI LGGIGLPG AV++
Sbjct 66 EFGHAYLAYRSGDRSVATKGYLTLNPLKYGDVTLSFLLPVLFIMLGGIGLPGGAVWIDRG 125
Query 121 FMTTA-RRTLVSLAGPTVNLALAMLLLAA-TRLLFDP--IHAVLWAGVAFLAFLQLTALV 176
+ R +L+S AGP N+ A+ L AA T+L D H V W+ ++FLAFLQ+TA +
Sbjct 126 RIPGRLRHSLISAAGPLANVVFAIALAAAVTQLRSDEPLDHLVFWSALSFLAFLQVTAAL 185
Query 177 LNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFD 236
LNLLPIPGLDG+ +EP+L R +A + L+ L P +N FF V+ + D
Sbjct 186 LNLLPIPGLDGFGIVEPYLPRSWVRKADEVGGYAFLALIALLWIPPVNRAFFDAVFTVTD 245
Query 237 LSGVSH 242
L GV
Sbjct 246 LFGVDQ 251
>gi|159039083|ref|YP_001538336.1| peptidase M50 [Salinispora arenicola CNS-205]
gi|157917918|gb|ABV99345.1| peptidase M50 [Salinispora arenicola CNS-205]
Length=265
Score = 185 bits (469), Expect = 7e-45, Method: Compositional matrix adjust.
Identities = 121/254 (48%), Positives = 155/254 (62%), Gaps = 10/254 (3%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
R + RPSP+FLGL+ L G L W V+ GVF+ V++GWLVSLCLHE+ HA
Sbjct 17 RAAFRPSPVFLGLVALFVFSGVLTWQGIGNVR----VGVFLFVVSGWLVSLCLHEYAHAL 72
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA- 125
A+R GD VA +GYLTL+P +YSHP+LS+ P+L + LGGIGLPG AV+V +
Sbjct 73 VAFRAGDRSVAHQGYLTLNPLKYSHPLLSIAFPVLVVLLGGIGLPGGAVWVDRHAIPGRL 132
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFD---PIHAVLWAGVAFLAFLQLTALVLNLLPI 182
R TLVSLAGP N+ ++L+ A RL P+ WA VA LAFLQLTA +LNLLP+
Sbjct 133 RHTLVSLAGPATNVVFTLVLVVAVRLAATGGGPVE--FWAAVALLAFLQLTASLLNLLPV 190
Query 183 PGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSH 242
PGLDG ++P L P +RA + + L L P +NGWFFG V+ + D G+
Sbjct 191 PGLDGGNMIQPWLTPPYRRAYDLFAPYGFLLLFALLWNPRINGWFFGTVFAVGDALGLPP 250
Query 243 RLAAAGSVLARFWS 256
L G L RFW
Sbjct 251 GLYRLGLELVRFWQ 264
>gi|329934902|ref|ZP_08284943.1| membrane protein [Streptomyces griseoaurantiacus M045]
gi|329305724|gb|EGG49580.1| membrane protein [Streptomyces griseoaurantiacus M045]
Length=265
Score = 183 bits (464), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 107/252 (43%), Positives = 149/252 (60%), Gaps = 5/252 (1%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+R R SP+FLG+L ++AV G W G QP VF+ V + W+VSLCLHE+ HA
Sbjct 7 RRSERRISPVFLGILAVSAVTGWATW-TGFAEQP--GVAVFLFVTSAWIVSLCLHEYAHA 63
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TA GD + +GYLTL+P +Y+H +LS+ LP+LF+ +GGIGLPG AV+V +
Sbjct 64 RTALHSGDFTIGAKGYLTLNPLKYTHALLSIVLPVLFVIMGGIGLPGGAVFVERGHIRGR 123
Query 126 -RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNLLPIP 183
+ + VS AGP N+ A+L A L D + + FLA LQ+TA +LNLLP+P
Sbjct 124 WKHSAVSAAGPLANVLFAVLCTAPFWLDALDGVPRPFRYALGFLALLQITAAILNLLPVP 183
Query 184 GLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHR 243
GLDGY +EP L +R + P F L+F+ + P++N FF +VY L + G+ +
Sbjct 184 GLDGYGVIEPWLSYNARRQMEPFAPFGLLFVFAVLWIPSVNETFFDMVYGLLNSLGIDNN 243
Query 244 LAAAGSVLARFW 255
A G L RFW
Sbjct 244 TTACGYELFRFW 255
>gi|145595826|ref|YP_001160123.1| peptidase M50 [Salinispora tropica CNB-440]
gi|145305163|gb|ABP55745.1| peptidase M50 [Salinispora tropica CNB-440]
Length=254
Score = 182 bits (463), Expect = 3e-44, Method: Compositional matrix adjust.
Identities = 119/254 (47%), Positives = 155/254 (62%), Gaps = 10/254 (3%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
R + RPSP+FLGL+ L + G L W ++ VF+ V++GWLVSLCLHE+ HA
Sbjct 6 RAAFRPSPVFLGLVALFVLSGVLTWRGIGNIR----VDVFLFVVSGWLVSLCLHEYAHAL 61
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMT-TA 125
A+R GD VA +GYLTL+P +YSHP+LS+ LP+L + LGGIGLPG AV+V +
Sbjct 62 VAFRAGDRSVAHQGYLTLNPLKYSHPLLSIALPVLVVLLGGIGLPGGAVWVDRHAIPGRL 121
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFD---PIHAVLWAGVAFLAFLQLTALVLNLLPI 182
R TLVSLAGP N+ ++L+ A RL P+ WA VA LAFLQLTA +LNLLP+
Sbjct 122 RHTLVSLAGPATNVLFTLVLVIAIRLAASGGGPVQ--FWAAVALLAFLQLTASLLNLLPV 179
Query 183 PGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSH 242
PGLDG ++P L P +R + + L L P +NGWFFG V+ + D G+
Sbjct 180 PGLDGGNMIQPWLTPPYRRVYDLFAPYGFLLLFALLWNPRINGWFFGTVFAVGDALGLPP 239
Query 243 RLAAAGSVLARFWS 256
L G L RFW
Sbjct 240 DLYRLGLDLVRFWQ 253
>gi|291440021|ref|ZP_06579411.1| membrane protein [Streptomyces ghanaensis ATCC 14672]
gi|291342916|gb|EFE69872.1| membrane protein [Streptomyces ghanaensis ATCC 14672]
Length=266
Score = 182 bits (462), Expect = 4e-44, Method: Compositional matrix adjust.
Identities = 112/257 (44%), Positives = 150/257 (59%), Gaps = 5/257 (1%)
Query 2 SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHE 61
+ T + R SP+FLG+L +TAV G W G QP VF+ V A W+VSLCLHE
Sbjct 3 TATLRPRDRRISPVFLGILAVTAVTGWATW-TGFAAQP--GVAVFLFVTAAWIVSLCLHE 59
Query 62 FGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWF 121
+ HA TA GD V +GYLTL+P +Y+H +LS+ LP+LF+ +GGIGLPG AV++
Sbjct 60 YAHARTALHSGDISVGAKGYLTLNPMKYTHALLSIVLPVLFVIMGGIGLPGGAVFIERGR 119
Query 122 MTTA-RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNL 179
+ R +L+S AGP N+ A++ A L D + A +AFLA LQ+TA +LN
Sbjct 120 IRGRWRHSLISAAGPLTNVLFAVVCTAPFWLGALDGVPADFRFALAFLALLQVTAAILNF 179
Query 180 LPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSG 239
LP+PGLDGY +EP L +R + P F L+F+ L P +NG FFGVV L + G
Sbjct 180 LPVPGLDGYGVIEPWLSYGVRRQVEPFAPFGLLFVFALLWLPAVNGAFFGVVDSLLNALG 239
Query 240 VSHRLAAAGSVLARFWS 256
+ G L RFW
Sbjct 240 IHEFDTYCGYDLFRFWQ 256
>gi|254386853|ref|ZP_05002141.1| membrane protein [Streptomyces sp. Mg1]
gi|194345686|gb|EDX26652.1| membrane protein [Streptomyces sp. Mg1]
Length=267
Score = 182 bits (462), Expect = 5e-44, Method: Compositional matrix adjust.
Identities = 109/258 (43%), Positives = 149/258 (58%), Gaps = 5/258 (1%)
Query 1 VSETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLH 60
+ G R R S +FLG++ + AV G W LA VF+ V + W+VSLCLH
Sbjct 1 MGHQGGRGERRISAVFLGIVAVMAVTGWAVWTDYAASPGLA---VFLFVTSAWIVSLCLH 57
Query 61 EFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTW 120
E+ HA TA GD V +GYLTL+P +Y+H +LS+ LP+LF+ +GGIGLPG AVY+
Sbjct 58 EYAHARTALHGGDLTVGAKGYLTLNPLKYTHALLSIVLPVLFVIMGGIGLPGGAVYIERD 117
Query 121 FMTTA-RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLN 178
+ + +L+S AGP N+A A++ A L D + +AFLA LQ++A +LN
Sbjct 118 RIAGRWKHSLISAAGPLANVAFAIVCTAPFWLHALDGVPVAFRFALAFLALLQVSAAILN 177
Query 179 LLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLS 238
LP+PGLDGY +EP L +R LAP F L+ L + P +N +FFGVV +
Sbjct 178 FLPVPGLDGYGIIEPWLSHRVRRELAPIAPFGLIALFAMLWIPEVNQFFFGVVDGVLSAL 237
Query 239 GVSHRLAAAGSVLARFWS 256
GV+ R A G L RFW
Sbjct 238 GVNERAAYCGQDLYRFWQ 255
>gi|302550966|ref|ZP_07303308.1| membrane protein [Streptomyces viridochromogenes DSM 40736]
gi|302468584|gb|EFL31677.1| membrane protein [Streptomyces viridochromogenes DSM 40736]
Length=266
Score = 180 bits (456), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 108/257 (43%), Positives = 148/257 (58%), Gaps = 5/257 (1%)
Query 2 SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHE 61
+ T + R SP+FLG+L +TAV G W G QP VF+ V A W+VSLCLHE
Sbjct 3 TATSRHSERRISPVFLGILAVTAVTGWATW-TGFAEQP--GVAVFLFVTAAWIVSLCLHE 59
Query 62 FGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWF 121
+ HA TA GD V +GYLTL+P +Y+H +LS+ LP++F+ +GGIGLPG AV++
Sbjct 60 YAHARTALHSGDISVGAKGYLTLNPLKYTHALLSIVLPVIFVIMGGIGLPGGAVFIERGR 119
Query 122 MTTA-RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNL 179
+ R +L+S AGP N+ A++ A L D + +AFLA LQ+TA +LN
Sbjct 120 IQGRWRHSLISAAGPLTNVLFAVVCTAPFWLDALDGVPTDFRFALAFLALLQVTAALLNF 179
Query 180 LPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSG 239
LP+PGLDGY +EP L +R + P F L+F+ L P +NG FF V+ + G
Sbjct 180 LPVPGLDGYGVIEPWLSYGVRRQVEPFAPFGLLFVFALLWLPAVNGVFFDVIDTILKSLG 239
Query 240 VSHRLAAAGSVLARFWS 256
+S G L RFW
Sbjct 240 ISDVETYCGQELYRFWQ 256
>gi|302560974|ref|ZP_07313316.1| membrane protein [Streptomyces griseoflavus Tu4000]
gi|302478592|gb|EFL41685.1| membrane protein [Streptomyces griseoflavus Tu4000]
Length=266
Score = 177 bits (448), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 107/253 (43%), Positives = 146/253 (58%), Gaps = 5/253 (1%)
Query 6 QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHA 65
+ R SP+FLG+L +TAV G W + +A VF+ V A W+VSLCLHE+ HA
Sbjct 7 RHSDRRISPVFLGILAVTAVTGWATWTGFAELPGVA---VFLFVTAAWIVSLCLHEYAHA 63
Query 66 FTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA 125
TA GD V +GYLTL+P +Y+H +LS+ LP++F+ +GGIGLPG AV++ +
Sbjct 64 RTALHSGDISVGAKGYLTLNPMKYTHALLSIVLPVVFVIMGGIGLPGGAVFIERGRIRGR 123
Query 126 -RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNLLPIP 183
R +L+S AGP N+ A++ A L D + A +AFLA LQ+TA +LN LP+P
Sbjct 124 WRHSLISAAGPLTNVLFAVVCTAPFWLGALDGVPADFRFALAFLALLQVTAAILNFLPVP 183
Query 184 GLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHR 243
GLDGY +EP L +R + P F L+F+ L P +NG FF VV L G+
Sbjct 184 GLDGYGVIEPWLSHGVRRQVEPFAPFGLLFVFALLWVPAVNGVFFDVVDSLLGALGIHEL 243
Query 244 LAAAGSVLARFWS 256
G L RFW
Sbjct 244 DTYCGYDLFRFWQ 256
>gi|320011125|gb|ADW05975.1| peptidase M50 [Streptomyces flavogriseus ATCC 33331]
Length=270
Score = 176 bits (445), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 106/251 (43%), Positives = 145/251 (58%), Gaps = 5/251 (1%)
Query 11 RPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAFTAWR 70
R SPIF+G+ + AV G W + + +A VF+ V A W+VSLCLHE+ HA TA
Sbjct 12 RVSPIFVGIFAVMAVSGWAVWT--DFAEQTGFA-VFLFVTAAWIVSLCLHEYAHARTALH 68
Query 71 FGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA-RRTL 129
GD + +GYLTL+P +Y+H +LS+ LP+LF+ +GGIGLPG AVY+ ++ + +L
Sbjct 69 SGDISIGAKGYLTLNPLKYTHALLSIVLPVLFVIMGGIGLPGGAVYIERGRISGRWKHSL 128
Query 130 VSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLDGY 188
+S AGP N+ A++ A L D + +AFLA LQ+TA +LN LP+PGLDGY
Sbjct 129 ISAAGPLTNVLFAVVCTAPFWLGALDGVPMPFRFALAFLALLQVTAAILNFLPVPGLDGY 188
Query 189 AALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAAAG 248
+EP L + +R + P F L+ + L P LNG FF V L GVS G
Sbjct 189 GVIEPWLSYKVRRQVEPFAPFGLIAVFALLWIPELNGVFFDAVDALLRGLGVSEVETYCG 248
Query 249 SVLARFWSIWF 259
RFW WF
Sbjct 249 LDTYRFWQEWF 259
>gi|294629020|ref|ZP_06707580.1| membrane protein [Streptomyces sp. e14]
gi|292832353|gb|EFF90702.1| membrane protein [Streptomyces sp. e14]
Length=266
Score = 175 bits (443), Expect = 6e-42, Method: Compositional matrix adjust.
Identities = 106/257 (42%), Positives = 148/257 (58%), Gaps = 5/257 (1%)
Query 2 SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHE 61
+ T + R SP+F+G+L +TAV G W G QP VF+ V A W+VSLCLHE
Sbjct 3 TATTRPSDRRISPVFVGILAVTAVTGWATW-TGFAEQP--GVAVFLFVTAAWVVSLCLHE 59
Query 62 FGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWF 121
+ HA TA GD V +GYLTL+P +Y+H +LS+ LP++F+ +GGIGLPG AV++
Sbjct 60 YAHARTALHGGDITVGAKGYLTLNPLKYTHALLSIVLPVVFVIMGGIGLPGGAVFIERGR 119
Query 122 MTTA-RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNL 179
+ R +L+S AGP N+ A++ A L D + A +AFLA LQ+TA +LN
Sbjct 120 IKGRWRHSLISAAGPLTNVLFAVVCTAPFWLDALDGVPADFRFALAFLALLQVTAAILNF 179
Query 180 LPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSG 239
LP+PGLDGY +EP L +R + P F L+F+ L P +N FF V+ + G
Sbjct 180 LPVPGLDGYGVIEPWLSYGVKRQVEPFAPFGLLFVFALLWVPAVNSAFFDVIDSILRALG 239
Query 240 VSHRLAAAGSVLARFWS 256
++ G L RFW
Sbjct 240 ITDLDTYCGQGLYRFWE 256
>gi|330469399|ref|YP_004407142.1| peptidase M50 [Verrucosispora maris AB-18-032]
gi|328812370|gb|AEB46542.1| peptidase M50 [Verrucosispora maris AB-18-032]
Length=263
Score = 175 bits (443), Expect = 6e-42, Method: Compositional matrix adjust.
Identities = 121/254 (48%), Positives = 153/254 (61%), Gaps = 10/254 (3%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
R + RPSPIFL L+ L G L W V+ VF V+ GW+VSLCLHE+ HA
Sbjct 16 RAAFRPSPIFLALVALLITCGVLTWHGIGNVR----LAVFGFVVTGWVVSLCLHEYAHAL 71
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA- 125
A+RFGD VA RGYLTL+P +YSHP+LS+ LP++ + LGGIGLPG AV+V +
Sbjct 72 VAYRFGDRGVAHRGYLTLNPLKYSHPLLSIALPVVVVLLGGIGLPGGAVWVDRHVIAGRL 131
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLF---DPIHAVLWAGVAFLAFLQLTALVLNLLPI 182
R TLVSLAGP N+ A++L+A RL P+ WA VA L FLQLTA VLNLLP+
Sbjct 132 RHTLVSLAGPATNVVFALVLVAVLRLGAAGGGPVE--FWAAVALLGFLQLTASVLNLLPV 189
Query 183 PGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSH 242
PGLDG ++P L P+ +R + + L L P + GWFF V+ + D G+
Sbjct 190 PGLDGGNMIQPWLDPQWRRMYDLFAPYGFILLFALLWNPRIGGWFFSAVFAVADFLGLPP 249
Query 243 RLAAAGSVLARFWS 256
L A G L RFWS
Sbjct 250 WLYATGLELVRFWS 263
>gi|29832480|ref|NP_827114.1| hypothetical protein SAV_5937 [Streptomyces avermitilis MA-4680]
gi|29609599|dbj|BAC73649.1| putative membrane protein [Streptomyces avermitilis MA-4680]
Length=266
Score = 175 bits (443), Expect = 7e-42, Method: Compositional matrix adjust.
Identities = 101/257 (40%), Positives = 148/257 (58%), Gaps = 5/257 (1%)
Query 2 SETGQRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHE 61
+ +R R SP+F+G++ +TAV G AW G QP VF+ V A W+VSLCLHE
Sbjct 3 TAASRRSDRRISPVFIGIVAVTAVTGWAAW-TGFAAQP--GIAVFLFVTAAWIVSLCLHE 59
Query 62 FGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWF 121
+ HA TA GD + +GYLTL+P +Y+H +LS+ LP++F+ +GGIGLPG AV++
Sbjct 60 YAHARTALHSGDISIGAKGYLTLNPLKYTHALLSIVLPVIFVIMGGIGLPGGAVFIERQR 119
Query 122 MTTA-RRTLVSLAGPTVNLALAMLLLAATRL-LFDPIHAVLWAGVAFLAFLQLTALVLNL 179
+ + +L+S AGP N+ A + A L D + +AFLA LQ+TA +LN
Sbjct 120 IQGRWKHSLISAAGPLTNVLFAAVCTAPFWLHALDGVPRDFQYALAFLALLQVTAAILNF 179
Query 180 LPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSG 239
LP+PGLDGY +EP L + +R + P F L+ + + P++NG FF + + + G
Sbjct 180 LPVPGLDGYGVIEPWLSYDIRRQVEPFAPFGLLAVFAILWIPSVNGVFFDAIDAILNGLG 239
Query 240 VSHRLAAAGSVLARFWS 256
+ G L RFW
Sbjct 240 IDDIHRYCGQELYRFWQ 256
>gi|238060340|ref|ZP_04605049.1| peptidase M50 [Micromonospora sp. ATCC 39149]
gi|237882151|gb|EEP70979.1| peptidase M50 [Micromonospora sp. ATCC 39149]
Length=265
Score = 174 bits (442), Expect = 8e-42, Method: Compositional matrix adjust.
Identities = 123/252 (49%), Positives = 159/252 (64%), Gaps = 6/252 (2%)
Query 7 RESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCLHEFGHAF 66
R + RPSP+FL L+ L A G LAW V+ VF+ V++GWLVSLCLHE+ HA
Sbjct 17 RAAFRPSPVFLALVALFATSGVLAWNRFGNVR----FDVFLFVVSGWLVSLCLHEYAHAV 72
Query 67 TAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHTWFMTTA- 125
A+R GD D+A RGYLTL+P +Y+HP+LS+ LP++ + LGGIGLPG AV+V +
Sbjct 73 VAYRAGDTDIAHRGYLTLNPLKYTHPLLSIVLPVVVVLLGGIGLPGGAVWVDRHAIPGRL 132
Query 126 RRTLVSLAGPTVNLALAMLLLAATRLLFDPIHAV-LWAGVAFLAFLQLTALVLNLLPIPG 184
R TLVSLAGP N+ + L+A R+ F +V WAGVA LAFLQLTA VLNLLP+PG
Sbjct 133 RHTLVSLAGPATNVLFTLALVAVLRVGFGGGGSVEFWAGVALLAFLQLTASVLNLLPVPG 192
Query 185 LDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRL 244
LDG ++P L P+ +R F + L L P + GWFF V+ + +L G+ L
Sbjct 193 LDGGNMIQPWLNPQWRRMYDLFAPFGFILLFALLWNPRIGGWFFDAVFAVANLLGLPPWL 252
Query 245 AAAGSVLARFWS 256
AAG L RFW
Sbjct 253 YAAGLDLIRFWQ 264
>gi|311895766|dbj|BAJ28174.1| putative peptidase M50 family protein [Kitasatospora setae KM-6054]
Length=272
Score = 174 bits (442), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 115/273 (43%), Positives = 156/273 (58%), Gaps = 21/273 (7%)
Query 2 SETGQRESV-RPSPIFLGLLG-LTAVGGALAWLAGETVQPLAYAGVFVMVIAGWLVSLCL 59
+ TGQR + R SPIFL L L A G ALA G GVF+ V++GW+VSLCL
Sbjct 4 ASTGQRSAENRVSPIFLALAATLIASGWALATGWGND-----RFGVFLFVVSGWMVSLCL 58
Query 60 HEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLPMLFIALGGIGLPGAAVYVHT 119
HE+ HA TA GD V +GYLTL+P +Y H +LS LP++F+ +GGIGLPG AVY+
Sbjct 59 HEYAHARTALAGGDITVGTKGYLTLNPLKYGHVVLSFVLPVIFVIMGGIGLPGGAVYIER 118
Query 120 WFMTTA-RRTLVSLAGPTVNLALAML-LLAATRLLFD----PIH---AVLW-----AGVA 165
+ + +LVS AGP VN+A ++ L+ ++ FD P H LW A +
Sbjct 119 DRIAGRFKHSLVSAAGPLVNIAFGVVTLVLVSQGWFDNPDVPAHYDGQELWFSPLPAALG 178
Query 166 FLAFLQLTALVLNLLPIPGLDGYAALEPHLRPETQRALAPAKQFALVFLLVLFLAPTLNG 225
FLA+LQ+TA +LNLLP+PGLDGY +EP L + +RA+AP + ++ L L
Sbjct 179 FLAYLQVTAAILNLLPVPGLDGYGIVEPWLSYKVRRAVAPYAPYTMLLLFALMWQSQAGQ 238
Query 226 WFFGVVYWLFDLSGVSHRLAAAGSVLARFWSIW 258
W W+F+L G R G +L FW +
Sbjct 239 WIRDAAVWVFELFGADPRYIDLGRILFSFWKTY 271
Lambda K H
0.329 0.143 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 382276364284
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40