BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0406c
Length=272
Score E
Sequences producing significant alignments: (Bits) Value
gi|15607547|ref|NP_214920.1| beta lactamase like protein [Mycoba... 548 3e-154
gi|289572991|ref|ZP_06453218.1| beta lactamase like protein [Myc... 546 9e-154
gi|15839792|ref|NP_334829.1| metallo-beta-lactamase superfamily ... 512 2e-143
gi|289760522|ref|ZP_06519900.1| beta lactamase like protein [Myc... 469 2e-130
gi|240168868|ref|ZP_04747527.1| beta lactamase like protein [Myc... 405 3e-111
gi|15827053|ref|NP_301316.1| hypothetical protein ML0270 [Mycoba... 381 5e-104
gi|254777200|ref|ZP_05218716.1| metallo-beta-lactamase superfami... 380 9e-104
gi|296167863|ref|ZP_06850046.1| metallo-beta-lactamase superfami... 376 2e-102
gi|342859117|ref|ZP_08715771.1| hypothetical protein MCOL_09573 ... 374 8e-102
gi|118618248|ref|YP_906580.1| beta lactamase-like protein [Mycob... 374 8e-102
gi|118463433|ref|YP_883889.1| metallo-beta-lactamase [Mycobacter... 372 3e-101
gi|41409981|ref|NP_962817.1| hypothetical protein MAP3883c [Myco... 370 1e-100
gi|254818874|ref|ZP_05223875.1| hypothetical protein MintA_03059... 365 3e-99
gi|333989019|ref|YP_004521633.1| beta lactamase-like protein [My... 352 2e-95
gi|5031436|gb|AAD38170.1|AF152397_1 beta-lactamase-like protein ... 314 1e-83
gi|120401712|ref|YP_951541.1| beta-lactamase domain-containing p... 311 5e-83
gi|118473438|ref|YP_885181.1| metallo-beta-lactamase superfamily... 290 2e-76
gi|145220817|ref|YP_001131495.1| beta-lactamase domain-containin... 284 1e-74
gi|108797511|ref|YP_637708.1| beta-lactamase-like protein [Mycob... 278 8e-73
gi|5031430|gb|AAD38166.1|AF152395_1 beta-lactamase-like protein ... 258 7e-67
gi|169631309|ref|YP_001704958.1| beta-lactamase-like protein [My... 254 7e-66
gi|5031433|gb|AAD38168.1|AF152396_1 beta-lactamase-like protein ... 253 2e-65
gi|297197394|ref|ZP_06914791.1| beta-lactamase [Streptomyces svi... 221 6e-56
gi|302549091|ref|ZP_07301433.1| beta-lactamase [Streptomyces vir... 221 1e-55
gi|302556952|ref|ZP_07309294.1| metallo-beta-lactamase superfami... 213 4e-53
gi|21225577|ref|NP_631356.1| hypothetical protein SCO7301 [Strep... 208 7e-52
gi|289767276|ref|ZP_06526654.1| conserved hypothetical protein [... 208 7e-52
gi|291441348|ref|ZP_06580738.1| conserved hypothetical protein [... 204 8e-51
gi|294634092|ref|ZP_06712647.1| metallo-beta-lactamase superfami... 199 3e-49
gi|318062028|ref|ZP_07980749.1| beta-lactamase domain protein [S... 199 5e-49
gi|333028937|ref|ZP_08457001.1| hypothetical protein STTU_6441 [... 198 6e-49
gi|126348089|emb|CAJ89810.1| putative beta-lactamase [Streptomyc... 197 1e-48
gi|329935776|ref|ZP_08285580.1| hypothetical protein SGM_1072 [S... 195 5e-48
gi|111024903|ref|YP_707323.1| beta-lactamase [Rhodococcus jostii... 187 2e-45
gi|111026302|ref|YP_708585.1| hypothetical protein RHA1_ro10234 ... 186 3e-45
gi|256389447|ref|YP_003111011.1| beta-lactamase domain-containin... 185 6e-45
gi|296139003|ref|YP_003646246.1| beta-lactamase [Tsukamurella pa... 182 7e-44
gi|111017777|ref|YP_700749.1| beta lactamase [Rhodococcus jostii... 174 1e-41
gi|119964472|ref|YP_947179.1| metallo-beta-lactamase superfamily... 172 4e-41
gi|219882988|ref|YP_002478152.1| beta-lactamase domain protein [... 172 5e-41
gi|326384285|ref|ZP_08205966.1| beta-lactamase domain-containing... 172 5e-41
gi|262200279|ref|YP_003271487.1| beta-lactamase [Gordonia bronch... 169 4e-40
gi|312139961|ref|YP_004007297.1| metallo-beta-lactamase superfam... 164 9e-39
gi|325674150|ref|ZP_08153839.1| metallo-beta-lactamase superfami... 160 1e-37
gi|229488995|ref|ZP_04382861.1| beta-lactamase domain protein [R... 159 3e-37
gi|308177387|ref|YP_003916793.1| metallo-beta-lactamase [Arthrob... 159 4e-37
gi|226308338|ref|YP_002768298.1| beta-lactamase [Rhodococcus ery... 158 9e-37
gi|343926198|ref|ZP_08765707.1| putative beta-lactamase [Gordoni... 150 2e-34
gi|238494956|ref|XP_002378714.1| conserved hypothetical protein ... 150 2e-34
gi|169777739|ref|XP_001823335.1| hypothetical protein AOR_1_9121... 147 1e-33
>gi|15607547|ref|NP_214920.1| beta lactamase like protein [Mycobacterium tuberculosis H37Rv]
gi|31791584|ref|NP_854077.1| beta lactamase like protein [Mycobacterium bovis AF2122/97]
gi|121636320|ref|YP_976543.1| Beta lactamase like protein [Mycobacterium bovis BCG str. Pasteur
1173P2]
45 more sequence titles
Length=272
Score = 548 bits (1413), Expect = 3e-154, Method: Compositional matrix adjust.
Identities = 272/272 (100%), Positives = 272/272 (100%), Gaps = 0/272 (0%)
Query 1 MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGD 60
MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGD
Sbjct 1 MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGD 60
Query 61 RAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYR 120
RAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYR
Sbjct 61 RAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYR 120
Query 121 ENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPG 180
ENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPG
Sbjct 121 ENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPG 180
Query 181 HTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNI 240
HTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNI
Sbjct 181 HTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNI 240
Query 241 LAPGHGELWHGPIRKATDEALERAQKSNHVFR 272
LAPGHGELWHGPIRKATDEALERAQKSNHVFR
Sbjct 241 LAPGHGELWHGPIRKATDEALERAQKSNHVFR 272
>gi|289572991|ref|ZP_06453218.1| beta lactamase like protein [Mycobacterium tuberculosis K85]
gi|339630475|ref|YP_004722117.1| beta-lactamase [Mycobacterium africanum GM041182]
gi|289537422|gb|EFD42000.1| beta lactamase like protein [Mycobacterium tuberculosis K85]
gi|339329831|emb|CCC25480.1| BETA LACTAMASE like protein [Mycobacterium africanum GM041182]
Length=272
Score = 546 bits (1408), Expect = 9e-154, Method: Compositional matrix adjust.
Identities = 271/272 (99%), Positives = 271/272 (99%), Gaps = 0/272 (0%)
Query 1 MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGD 60
MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGD
Sbjct 1 MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGD 60
Query 61 RAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYR 120
RAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHS PVYCHAEEVGHAKREYR
Sbjct 61 RAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHSMPVYCHAEEVGHAKREYR 120
Query 121 ENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPG 180
ENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPG
Sbjct 121 ENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPG 180
Query 181 HTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNI 240
HTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNI
Sbjct 181 HTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNI 240
Query 241 LAPGHGELWHGPIRKATDEALERAQKSNHVFR 272
LAPGHGELWHGPIRKATDEALERAQKSNHVFR
Sbjct 241 LAPGHGELWHGPIRKATDEALERAQKSNHVFR 272
>gi|15839792|ref|NP_334829.1| metallo-beta-lactamase superfamily protein [Mycobacterium tuberculosis
CDC1551]
gi|308231543|ref|ZP_07412837.2| beta lactamase like protein [Mycobacterium tuberculosis SUMu001]
gi|308369384|ref|ZP_07666725.1| beta lactamase like protein [Mycobacterium tuberculosis SUMu002]
20 more sequence titles
Length=252
Score = 512 bits (1319), Expect = 2e-143, Method: Compositional matrix adjust.
Identities = 252/252 (100%), Positives = 252/252 (100%), Gaps = 0/252 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA
Sbjct 1 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW
Sbjct 61 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL 200
GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL
Sbjct 121 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL 180
Query 201 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 260
ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA
Sbjct 181 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 240
Query 261 LERAQKSNHVFR 272
LERAQKSNHVFR
Sbjct 241 LERAQKSNHVFR 252
>gi|289760522|ref|ZP_06519900.1| beta lactamase like protein [Mycobacterium tuberculosis GM 1503]
gi|289708028|gb|EFD72044.1| beta lactamase like protein [Mycobacterium tuberculosis GM 1503]
Length=231
Score = 469 bits (1206), Expect = 2e-130, Method: Compositional matrix adjust.
Identities = 230/231 (99%), Positives = 231/231 (100%), Gaps = 0/231 (0%)
Query 42 VLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREH 101
+LVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREH
Sbjct 1 MLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREH 60
Query 102 STPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPL 161
STPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPL
Sbjct 61 STPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPL 120
Query 162 TAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSH 221
TAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSH
Sbjct 121 TAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSH 180
Query 222 SQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQKSNHVFR 272
SQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQKSNHVFR
Sbjct 181 SQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQKSNHVFR 231
>gi|240168868|ref|ZP_04747527.1| beta lactamase like protein [Mycobacterium kansasii ATCC 12478]
Length=254
Score = 405 bits (1041), Expect = 3e-111, Method: Compositional matrix adjust.
Identities = 197/242 (82%), Positives = 213/242 (89%), Gaps = 0/242 (0%)
Query 23 ELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIV 82
ELVQ+TDKV LA G AVNWVLVTDDTGV+LIDAGYPGDR EVLASL LGY PGDVRAI+
Sbjct 8 ELVQVTDKVQLAHGQAVNWVLVTDDTGVMLIDAGYPGDREEVLASLRLLGYQPGDVRAIL 67
Query 83 LTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGI 142
LTHAHIDHLG+AIWFAREH TPVYCHA+EVGHAKREY E S+ D+ALR WRPR AVW
Sbjct 68 LTHAHIDHLGTAIWFAREHHTPVYCHADEVGHAKREYLEQVSLLDIALRIWRPRWAVWAA 127
Query 143 HLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALIT 202
H+ R GGL DGIPTAQPLTAE AA LPG PMA+FTPGHT+GHCSY+VDGVLASGDALIT
Sbjct 128 HVARSGGLVRDGIPTAQPLTAEVAAQLPGHPMAVFTPGHTNGHCSYLVDGVLASGDALIT 187
Query 203 GHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALE 262
GHP+LR GPQLLPA+FS+SQQN IRSL+ALALLET ILAPGHGELW GPIR ATDEAL+
Sbjct 188 GHPLLRRDGPQLLPAIFSYSQQNCIRSLSALALLETEILAPGHGELWRGPIRGATDEALK 247
Query 263 RA 264
RA
Sbjct 248 RA 249
>gi|15827053|ref|NP_301316.1| hypothetical protein ML0270 [Mycobacterium leprae TN]
gi|221229531|ref|YP_002502947.1| hypothetical protein MLBr_00270 [Mycobacterium leprae Br4923]
gi|3129988|emb|CAA18938.1| hypothetical protein MLCB4.17 [Mycobacterium leprae]
gi|13092601|emb|CAC29778.1| conserved hypothetical protein [Mycobacterium leprae]
gi|219932638|emb|CAR70363.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=251
Score = 381 bits (979), Expect = 5e-104, Method: Compositional matrix adjust.
Identities = 182/243 (75%), Positives = 205/243 (85%), Gaps = 0/243 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A L Q+TD VH ARG AVNW LV DDTGV+LID GYPGDR +V+ASL +LGY GDVRAI
Sbjct 4 ATLFQVTDSVHFARGDAVNWALVADDTGVMLIDTGYPGDRDDVVASLRQLGYEAGDVRAI 63
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
+LTHAHIDH+GSAIWFA +H TPVYCHA+EVGH KREY E S+ ++A+R W+PR A+W
Sbjct 64 LLTHAHIDHMGSAIWFASKHRTPVYCHADEVGHTKREYLEQVSLLNIAMRVWQPRWAIWS 123
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALI 201
H+LR GGL GIPTAQPLTAE AAGLPG PMAIFTPGHT GHCSYVVDGVL SGDALI
Sbjct 124 GHVLRSGGLIRGGIPTAQPLTAETAAGLPGHPMAIFTPGHTGGHCSYVVDGVLISGDALI 183
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEAL 261
TGHP+LRHRGPQLL AVFSHSQ+ +RSL AL LLET ILAPGHGELWHGPIR+AT+ AL
Sbjct 184 TGHPLLRHRGPQLLTAVFSHSQKQCLRSLDALGLLETRILAPGHGELWHGPIREATEAAL 243
Query 262 ERA 264
++A
Sbjct 244 KQA 246
>gi|254777200|ref|ZP_05218716.1| metallo-beta-lactamase superfamily protein [Mycobacterium avium
subsp. avium ATCC 25291]
gi|5031427|gb|AAD38164.1|AF152394_2 beta-lactamase-like protein [Mycobacterium avium subsp. avium
ATCC 25291]
Length=247
Score = 380 bits (977), Expect = 9e-104, Method: Compositional matrix adjust.
Identities = 178/238 (75%), Positives = 207/238 (87%), Gaps = 0/238 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
MAELVQ+TD VHLARG AVNW LV DDTGV+L+DAGYPGDR +VL SL +LGY PGDVRA
Sbjct 1 MAELVQVTDAVHLARGDAVNWTLVADDTGVMLVDAGYPGDREDVLGSLAELGYGPGDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
IVLTHAHIDHLG+AIW A EH PVYCHA+EVGHAKREY E S+FDVALR WRPR A W
Sbjct 61 IVLTHAHIDHLGTAIWLASEHGIPVYCHADEVGHAKREYLEQVSIFDVALRIWRPRWAKW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL 200
H++R GGL DGIPTAQPLTAE AAGLPG+P +F+PGHT+GHCSY++DGVL SGDAL
Sbjct 121 TAHVVRSGGLIRDGIPTAQPLTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDGVLVSGDAL 180
Query 201 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATD 258
ITGHP+LRHRGPQLLPA+FS+SQ++ IR+L+ALALL+T +L PGHG++W GPI++ATD
Sbjct 181 ITGHPLLRHRGPQLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHGDVWRGPIKEATD 238
>gi|296167863|ref|ZP_06850046.1| metallo-beta-lactamase superfamily protein [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896988|gb|EFG76611.1| metallo-beta-lactamase superfamily protein [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=247
Score = 376 bits (965), Expect = 2e-102, Method: Compositional matrix adjust.
Identities = 177/235 (76%), Positives = 205/235 (88%), Gaps = 0/235 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
MAEL+Q+TD+VHLARG AVNW LVTDDTGVLLIDAGYPGDR + LASL+ LGY P DVRA
Sbjct 1 MAELIQVTDRVHLARGDAVNWTLVTDDTGVLLIDAGYPGDRQDALASLSALGYGPEDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
++LTHAHIDHLGSAIWFA +H PVYCHA+EVGHAKREY E S+ DVALR WRPR A W
Sbjct 61 VLLTHAHIDHLGSAIWFAGDHGVPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWARW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL 200
H++R GGL DGIPTA PLTAE AAGLPGQP +F+PGHT+GHCSYVVDGVL SGDAL
Sbjct 121 TAHVVRSGGLIRDGIPTAAPLTAEVAAGLPGQPQPVFSPGHTNGHCSYVVDGVLVSGDAL 180
Query 201 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRK 255
ITGHP+LRHRGPQLLPA+FSHSQ++ IR+L+ALAL++T++L PGHG++W GPIR+
Sbjct 181 ITGHPLLRHRGPQLLPAIFSHSQRDCIRTLSALALIDTDVLLPGHGDVWRGPIRE 235
>gi|342859117|ref|ZP_08715771.1| hypothetical protein MCOL_09573 [Mycobacterium colombiense CECT
3035]
gi|342133358|gb|EGT86561.1| hypothetical protein MCOL_09573 [Mycobacterium colombiense CECT
3035]
Length=239
Score = 374 bits (960), Expect = 8e-102, Method: Compositional matrix adjust.
Identities = 181/239 (76%), Positives = 203/239 (85%), Gaps = 0/239 (0%)
Query 27 ITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHA 86
+TD V+LA+G AVNW LV D TGVLLIDAGYPGDR +VL+SL +L Y PGDVRA++LTHA
Sbjct 1 MTDTVYLAQGEAVNWTLVVDGTGVLLIDAGYPGDREDVLSSLRELSYGPGDVRAVLLTHA 60
Query 87 HIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLR 146
HIDHLGSAIW A E+ T VYCHAEEVGHAKREY E ASVFDVALR WRPR A WG+H+LR
Sbjct 61 HIDHLGSAIWLANEYGTDVYCHAEEVGHAKREYLEQASVFDVALRIWRPRWAAWGLHVLR 120
Query 147 RGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPM 206
GGL DGIP+ +PLTAE AAGLPG P A+FTPGHTSGHCSYVVDGVL SGDALITGHP+
Sbjct 121 SGGLIRDGIPSTRPLTAEVAAGLPGHPSAVFTPGHTSGHCSYVVDGVLVSGDALITGHPL 180
Query 207 LRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQ 265
LR GPQLLPAVFSHSQQNS+RSL ALALL+T +L PGHG++W GPIR+AT A+ AQ
Sbjct 181 LRRSGPQLLPAVFSHSQQNSLRSLDALALLDTEVLLPGHGDVWRGPIREATARAIVLAQ 239
>gi|118618248|ref|YP_906580.1| beta lactamase-like protein [Mycobacterium ulcerans Agy99]
gi|183980731|ref|YP_001849022.1| beta lactamase-like protein [Mycobacterium marinum M]
gi|118570358|gb|ABL05109.1| beta lactamase-like protein [Mycobacterium ulcerans Agy99]
gi|183174057|gb|ACC39167.1| beta lactamase-like protein [Mycobacterium marinum M]
Length=250
Score = 374 bits (960), Expect = 8e-102, Method: Compositional matrix adjust.
Identities = 183/244 (75%), Positives = 204/244 (84%), Gaps = 0/244 (0%)
Query 23 ELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIV 82
ELVQ+TDKVHLA+G AVNWVLVTD+TGV+LIDAGYPGDR VL SL LGY PGDVRAI+
Sbjct 7 ELVQVTDKVHLAQGPAVNWVLVTDETGVMLIDAGYPGDRNNVLTSLRTLGYGPGDVRAIL 66
Query 83 LTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGI 142
LTHAHIDHLG+AIWFA +H TPVYC A EVGHAKREY E+AS DV LRSWRPR A+WGI
Sbjct 67 LTHAHIDHLGTAIWFAAQHGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGI 126
Query 143 HLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALIT 202
HL+ RGGL G+P+ Q L+AE AA LPG P+ I TPGHTSGHCSY+VDGVLASGDALIT
Sbjct 127 HLVFRGGLRRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDGVLASGDALIT 186
Query 203 GHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALE 262
GHPMLRHRGPQLLPAVFS Q+ IRSL+ LA +E + LAPGHG LW GPIR AT+EA
Sbjct 187 GHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLWRGPIRLATEEARA 246
Query 263 RAQK 266
RAQ+
Sbjct 247 RAQR 250
>gi|118463433|ref|YP_883889.1| metallo-beta-lactamase [Mycobacterium avium 104]
gi|118164720|gb|ABK65617.1| metallo-beta-lactamase superfamily protein [Mycobacterium avium
104]
Length=247
Score = 372 bits (955), Expect = 3e-101, Method: Compositional matrix adjust.
Identities = 174/235 (75%), Positives = 203/235 (87%), Gaps = 0/235 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
MAELVQ+TD VHLARG AVNW LV DDTGV+L+DAGYPGDR +VL SL +LGY PGDVRA
Sbjct 1 MAELVQVTDAVHLARGDAVNWTLVADDTGVMLVDAGYPGDREDVLGSLAELGYGPGDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
IVLTHAHIDHLG+AIW A EH PVYCHA+EVGHAKREY E S+ DVALR WRPR A W
Sbjct 61 IVLTHAHIDHLGTAIWLASEHGIPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWAKW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL 200
H++R GGL DGIPTAQPLTAE AAGLPG+P +F+PGHT+GHCSY++DGVL SGDAL
Sbjct 121 TAHVVRSGGLIRDGIPTAQPLTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDGVLVSGDAL 180
Query 201 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRK 255
ITGHP+LRHRGPQLLPA+FS+SQ++ IR+L+ALALL+T +L PGHG++W GPI++
Sbjct 181 ITGHPLLRHRGPQLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHGDVWRGPIKE 235
>gi|41409981|ref|NP_962817.1| hypothetical protein MAP3883c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398814|gb|AAS06433.1| hypothetical protein MAP_3883c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336460376|gb|EGO39276.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium avium subsp.
paratuberculosis S397]
Length=247
Score = 370 bits (950), Expect = 1e-100, Method: Compositional matrix adjust.
Identities = 173/235 (74%), Positives = 203/235 (87%), Gaps = 0/235 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
MAELVQ+TD VHLARG AVNW LV DDTGV+L+DAGYPGDR +VL SL +LGY PGDVRA
Sbjct 1 MAELVQVTDAVHLARGDAVNWTLVADDTGVMLVDAGYPGDREDVLGSLAELGYGPGDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
IVLTHAHIDHLG+AIW A EH PVYCHA+EVGHAKREY E S+ DVALR WRPR A W
Sbjct 61 IVLTHAHIDHLGTAIWLASEHGIPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWAKW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDAL 200
H++R GGL DGIPTA+PLTAE AAGLPG+P +F+PGHT+GHCSY++DGVL SGDAL
Sbjct 121 TAHVVRSGGLIRDGIPTARPLTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDGVLVSGDAL 180
Query 201 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRK 255
ITGHP+LRHRGPQLLPA+FS+SQ++ IR+L+ALALL+T +L PGHG++W GPI++
Sbjct 181 ITGHPLLRHRGPQLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHGDVWRGPIKE 235
>gi|254818874|ref|ZP_05223875.1| hypothetical protein MintA_03059 [Mycobacterium intracellulare
ATCC 13950]
Length=236
Score = 365 bits (938), Expect = 3e-99, Method: Compositional matrix adjust.
Identities = 175/234 (75%), Positives = 200/234 (86%), Gaps = 0/234 (0%)
Query 31 VHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDH 90
+HLARG AVNW +V DDTGV+LIDAGYPGDR +VLASL +LG+ GDVRAI+LTHAHIDH
Sbjct 1 MHLARGDAVNWTIVADDTGVMLIDAGYPGDRPDVLASLRELGFDAGDVRAILLTHAHIDH 60
Query 91 LGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL 150
LGSAIWFA E+ T VYCHA+EVGHAKREY E ASVFDVA+R WRPR A WG+H++R GGL
Sbjct 61 LGSAIWFANEYGTDVYCHADEVGHAKREYLEQASVFDVAVRIWRPRWAAWGLHVVRSGGL 120
Query 151 TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPMLRHR 210
DGIP+ +PLTA+ AAGLPG PMA+FTPGHTSGHCSYVVDGVL SGDALITGHP+L+H
Sbjct 121 IRDGIPSTRPLTADVAAGLPGHPMAVFTPGHTSGHCSYVVDGVLVSGDALITGHPLLKHD 180
Query 211 GPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERA 264
GPQLLP VFS SQQNS+RSL ALALL+T +L PGHG +W GPIR+AT A+ A
Sbjct 181 GPQLLPEVFSRSQQNSLRSLDALALLDTEVLLPGHGAVWRGPIREATARAISLA 234
>gi|333989019|ref|YP_004521633.1| beta lactamase-like protein [Mycobacterium sp. JDM601]
gi|333484987|gb|AEF34379.1| beta lactamase-like protein [Mycobacterium sp. JDM601]
Length=241
Score = 352 bits (904), Expect = 2e-95, Method: Compositional matrix adjust.
Identities = 170/240 (71%), Positives = 201/240 (84%), Gaps = 0/240 (0%)
Query 27 ITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHA 86
+T++V+LARG AVNW+LVTD+TGVLLIDAGYPGDR +VLASL LGY DVRA++LTHA
Sbjct 1 MTERVYLARGEAVNWLLVTDETGVLLIDAGYPGDRTDVLASLGALGYHAADVRAVLLTHA 60
Query 87 HIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLR 146
H+DH G+AIW A+ + TPVYCHA+EVGHAKR Y E AS VA + WRP A W +H+LR
Sbjct 61 HVDHFGAAIWLAKTYGTPVYCHADEVGHAKRAYLEQASPLAVAPQLWRPSWARWSLHVLR 120
Query 147 RGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPM 206
GGL +GIP+AQPLT E AAGLPGQP AI TPGHT GHCSY+VDGVLASGDALITGHP+
Sbjct 121 NGGLNREGIPSAQPLTGEIAAGLPGQPAAIPTPGHTRGHCSYLVDGVLASGDALITGHPV 180
Query 207 LRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQK 266
L H GPQLLPA+FSHSQQ+ IRSL+ALALLET +LAPGHG++W GPIR+A + A++RA K
Sbjct 181 LAHTGPQLLPALFSHSQQDCIRSLSALALLETEVLAPGHGDVWRGPIREAAEAAIDRAGK 240
>gi|5031436|gb|AAD38170.1|AF152397_1 beta-lactamase-like protein [Mycobacterium phlei]
Length=243
Score = 314 bits (804), Expect = 1e-83, Method: Compositional matrix adjust.
Identities = 149/237 (63%), Positives = 179/237 (76%), Gaps = 0/237 (0%)
Query 24 LVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVL 83
L +TD VH A VNW LV D TGV+LIDAG+PG R +VLASL +LG+ P D+RAI+L
Sbjct 5 LSSVTDTVHFAYTDLVNWTLVADQTGVVLIDAGFPGHRDDVLASLRQLGFGPDDLRAILL 64
Query 84 THAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIH 143
THAH+DHLGSAIWFA+ H TPVYCHA EVGHAKREY E S DVA W+PR A W
Sbjct 65 THAHVDHLGSAIWFAKNHGTPVYCHAAEVGHAKREYLEQVSPLDVAKHIWQPRFATWTAT 124
Query 144 LLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITG 203
++R+GGL DGIPTAQP T + AA LPG P A+ TPGHT GHCS+VVDGVL SGDAL+TG
Sbjct 125 IVRKGGLVRDGIPTAQPYTEQVAASLPGTPRAVPTPGHTGGHCSFVVDGVLVSGDALVTG 184
Query 204 HPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 260
HP+ GPQLLP +F+H Q++ +RSL+AL LL+T +L PGHG +W G IR+A + A
Sbjct 185 HPVSTRSGPQLLPGLFNHDQRSCVRSLSALGLLDTEVLLPGHGPVWRGSIREAAERA 241
>gi|120401712|ref|YP_951541.1| beta-lactamase domain-containing protein [Mycobacterium vanbaalenii
PYR-1]
gi|119954530|gb|ABM11535.1| beta-lactamase domain protein [Mycobacterium vanbaalenii PYR-1]
Length=246
Score = 311 bits (798), Expect = 5e-83, Method: Compositional matrix adjust.
Identities = 150/237 (64%), Positives = 179/237 (76%), Gaps = 0/237 (0%)
Query 24 LVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVL 83
L ITD+VH A+ VNW LV +D GVLLIDAGYPG R EVL SL +LG+ DVRAI+L
Sbjct 5 LTAITDRVHFAQTDLVNWTLVAEDGGVLLIDAGYPGHREEVLESLGRLGFGATDVRAILL 64
Query 84 THAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIH 143
THAHIDH GSA+WFAREH TPVYCHA+EVGHAKREY E AS VA +W+PR W +
Sbjct 65 THAHIDHFGSAMWFAREHGTPVYCHADEVGHAKREYLEQASPLAVAAHAWQPRWLKWSLT 124
Query 144 LLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITG 203
L+R+GGL GIPT L+ + AAGLPG P+ + TPGHT GHCSYVVDGVL SGDALITG
Sbjct 125 LIRKGGLDRTGIPTTAALSEDIAAGLPGAPVCVPTPGHTGGHCSYVVDGVLVSGDALITG 184
Query 204 HPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 260
HP+ R RGPQLLP+VF+H + +RSL AL +L+T ++ PGHG +W GP+R A +A
Sbjct 185 HPVSRRRGPQLLPSVFNHDEVACLRSLEALGMLDTEVMLPGHGPVWRGPVRDAVAQA 241
>gi|118473438|ref|YP_885181.1| metallo-beta-lactamase superfamily protein [Mycobacterium smegmatis
str. MC2 155]
gi|4874247|gb|AAD31327.1| beta-lactamase-like protein [Mycobacterium smegmatis str. MC2
155]
gi|118174725|gb|ABK75621.1| metallo-beta-lactamase superfamily protein [Mycobacterium smegmatis
str. MC2 155]
Length=248
Score = 290 bits (741), Expect = 2e-76, Method: Compositional matrix adjust.
Identities = 138/241 (58%), Positives = 174/241 (73%), Gaps = 2/241 (0%)
Query 24 LVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVL 83
L +ITD+VH AR VNW LVT D GVLLIDAG+PG R +VL S+ +LG+ P D++A++L
Sbjct 5 LNKITDRVHFARTELVNWTLVTGDDGVLLIDAGFPGQREDVLDSVRQLGFGPDDIKAVLL 64
Query 84 THAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIH 143
THAH+DH G+AIW A+ + TPVYCHA+EVGHA+REY E A+ VA ++W+PR W +
Sbjct 65 THAHVDHFGTAIWLAKTYGTPVYCHADEVGHARREYLEQATPAGVARQAWQPRWLKWALA 124
Query 144 LLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITG 203
+ R+G GIP+ Q T E GLPG P AI TPGHT GHCSY+VDGVL +GDAL+TG
Sbjct 125 ISRQGAFDHSGIPSTQAFTPE--IGLPGNPTAIPTPGHTGGHCSYLVDGVLVAGDALVTG 182
Query 204 HPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALER 263
HP RGPQLL VF+H QQ +RSL AL LL+T +L PGHG++W G IR+ D+A
Sbjct 183 HPTSSRRGPQLLHQVFNHDQQACLRSLGALGLLDTEVLLPGHGDVWRGSIREMADQAASS 242
Query 264 A 264
A
Sbjct 243 A 243
>gi|145220817|ref|YP_001131495.1| beta-lactamase domain-containing protein [Mycobacterium gilvum
PYR-GCK]
gi|315442230|ref|YP_004075109.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium sp. Spyr1]
gi|145213303|gb|ABP42707.1| beta-lactamase domain protein [Mycobacterium gilvum PYR-GCK]
gi|315260533|gb|ADT97274.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium sp. Spyr1]
Length=247
Score = 284 bits (726), Expect = 1e-74, Method: Compositional matrix adjust.
Identities = 138/236 (59%), Positives = 169/236 (72%), Gaps = 1/236 (0%)
Query 21 MAELVQ-ITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVR 79
MA +V +TD+VH R VNW LV DD GV+LIDAG+PG R EVL SL+ LG+ GDVR
Sbjct 1 MAPVVTAVTDRVHFVRTELVNWTLVRDDDGVILIDAGFPGHRDEVLTSLHGLGFGVGDVR 60
Query 80 AIVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAV 139
AI+LTHAHIDH G+AIWFA H TPVYCHA+EV H++R++ E AS D+A +W+P
Sbjct 61 AILLTHAHIDHFGTAIWFAATHGTPVYCHADEVAHSRRDHLEQASPIDIAKHAWQPTWLK 120
Query 140 WGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDA 199
W + ++ +G LT GI + PLT AA LPG P+ I TPGHT GHCSYVVDGVL SGDA
Sbjct 121 WSVSIIGKGALTRAGIASTAPLTDHIAAALPGSPVCIPTPGHTGGHCSYVVDGVLVSGDA 180
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRK 255
LITGHP+ RGPQLLP+VF+H + RSL L L+T ++ PGHG LW GP+R
Sbjct 181 LITGHPVASRRGPQLLPSVFNHDEDACRRSLTTLGALDTEVILPGHGPLWRGPVRD 236
>gi|108797511|ref|YP_637708.1| beta-lactamase-like protein [Mycobacterium sp. MCS]
gi|119866597|ref|YP_936549.1| beta-lactamase domain-containing protein [Mycobacterium sp. KMS]
gi|126433133|ref|YP_001068824.1| beta-lactamase domain-containing protein [Mycobacterium sp. JLS]
gi|108767930|gb|ABG06652.1| beta-lactamase-like protein [Mycobacterium sp. MCS]
gi|119692686|gb|ABL89759.1| beta-lactamase domain protein [Mycobacterium sp. KMS]
gi|126232933|gb|ABN96333.1| beta-lactamase domain protein [Mycobacterium sp. JLS]
Length=242
Score = 278 bits (710), Expect = 8e-73, Method: Compositional matrix adjust.
Identities = 146/239 (62%), Positives = 171/239 (72%), Gaps = 0/239 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A L +TD+VHLAR VNW LVTD GVLLIDAGYPG R +V+ S+ +LG+ D+RAI
Sbjct 3 AALTAVTDRVHLARTDLVNWTLVTDGDGVLLIDAGYPGHRDDVVDSVRRLGFGIDDIRAI 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
+LTHAHIDH GSAIWFA H PVY HA+EVGHA+R+Y E S VA +WRPR W
Sbjct 63 LLTHAHIDHFGSAIWFAETHGVPVYTHADEVGHARRDYLEQVSPLAVARHAWRPRWLKWS 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALI 201
+ + +GG GIPTAQ LT E AA LPG P A+ TPGHT GHCSYVVDGVL SGDAL+
Sbjct 123 LTISGKGGTHRGGIPTAQALTDEIAATLPGTPAAVPTPGHTGGHCSYVVDGVLVSGDALV 182
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 260
TGHP+L PQLLP +F+H Q + SLAALA L+T +L PGHG LW GPIR+A A
Sbjct 183 TGHPLLSDTRPQLLPDLFNHDQARCVASLAALAALDTEVLLPGHGPLWRGPIREAAQAA 241
>gi|5031430|gb|AAD38166.1|AF152395_1 beta-lactamase-like protein [Mycobacterium chelonae]
Length=243
Score = 258 bits (659), Expect = 7e-67, Method: Compositional matrix adjust.
Identities = 128/242 (53%), Positives = 164/242 (68%), Gaps = 2/242 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
M E+ Q++D VH+ G AVNWV+ +DD+GV L D+GYPGDR +VL S+ LG+ P DVRA
Sbjct 1 MVEITQVSDAVHVVNGEAVNWVIASDDSGVALFDSGYPGDRDDVLKSIAALGHKPQDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
+VLTH HIDH+G+AIW+A EH PVY H E+G+ +R+Y + A F V L WRP W
Sbjct 61 VVLTHGHIDHMGTAIWWAAEHGVPVYAHNAELGNVRRDYVDQAEPFKVVLNLWRPGWLPW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG-VLASGDA 199
IH +R G DGIPTA PL E A LPG P+ I TPGH+ GHCS++V G VL GDA
Sbjct 121 VIHAMRLGAGVRDGIPTAAPLGPE-LADLPGAPVPIPTPGHSGGHCSFLVAGHVLVVGDA 179
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
+ITGHP+ GPQLLP F+ + + RS ALA ++ ++LAPGHG W G +R A +
Sbjct 180 IITGHPIASRSGPQLLPTPFTKDMEQARRSAQALAEVDADVLAPGHGPAWTGSLRDAVEI 239
Query 260 AL 261
AL
Sbjct 240 AL 241
>gi|169631309|ref|YP_001704958.1| beta-lactamase-like protein [Mycobacterium abscessus ATCC 19977]
gi|169243276|emb|CAM64304.1| Beta-lactamase-like protein [Mycobacterium abscessus]
Length=243
Score = 254 bits (650), Expect = 7e-66, Method: Compositional matrix adjust.
Identities = 127/243 (53%), Positives = 162/243 (67%), Gaps = 2/243 (0%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
M E+ Q++D VH+ G AVNWV+ +DD+GV L D+GYPGDR +VL S+ LG+ P DVRA
Sbjct 1 MVEITQVSDAVHVVNGEAVNWVIASDDSGVTLFDSGYPGDRDDVLKSIAALGHKPQDVRA 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
+VLTH HIDH+G+AIW+A EH PVY H E+G+ +R+Y + A V L WRP W
Sbjct 61 VVLTHGHIDHMGTAIWWAAEHGVPVYAHNAELGNVRRDYVDQAEPLKVVLNLWRPGWLPW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG-VLASGDA 199
IH +R G DGIPTA PL E A LPG P I TPGH+ GHCS++V G VL GDA
Sbjct 121 VIHAMRLGAGVRDGIPTAAPLGPE-LADLPGAPAPIPTPGHSGGHCSFLVAGHVLVVGDA 179
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
+ITGHP+ + GPQLLP F+ + + RS ALA ++ ++LAPGHG W G +R A
Sbjct 180 IITGHPVAKRSGPQLLPTPFTKDMEQARRSAEALADVDADVLAPGHGPAWIGSLRDAVQI 239
Query 260 ALE 262
AL
Sbjct 240 ALN 242
>gi|5031433|gb|AAD38168.1|AF152396_1 beta-lactamase-like protein [Mycobacterium fortuitum]
Length=244
Score = 253 bits (645), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 119/232 (52%), Positives = 159/232 (69%), Gaps = 2/232 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A L IT+ VH A+ VNW LVTD V+LIDAG+PG R +V+ S+ +LG+ D+ A+
Sbjct 3 AALTAITEHVHFAQTDLVNWTLVTDGDRVMLIDAGFPGQRDDVIGSVRQLGFAIDDIAAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
+LTHAHIDH G+AIW A+ TPV+CH E+GH KREY E A+ DV W+PR W
Sbjct 63 LLTHAHIDHFGTAIWLAKTRGTPVFCHTAELGHTKREYLEQAAPADVVRNIWQPRWLKWA 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALI 201
+ +GG+ GIPTA+ LT + LPG P+ + TPGHT GHCS++VDGVL SGDAL+
Sbjct 123 ATITAKGGMNHAGIPTARALTDD--DDLPGNPVPVPTPGHTGGHCSFIVDGVLVSGDALV 180
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPI 253
TGHP+L++ GP LLPA+F+H + + SL LA +E +++ PGHG +W G I
Sbjct 181 TGHPLLKNTGPTLLPALFNHDEAGCLSSLKTLATVEADVMLPGHGPVWRGSI 232
>gi|297197394|ref|ZP_06914791.1| beta-lactamase [Streptomyces sviceus ATCC 29083]
gi|197717601|gb|EDY61635.1| beta-lactamase [Streptomyces sviceus ATCC 29083]
Length=248
Score = 221 bits (564), Expect = 6e-56, Method: Compositional matrix adjust.
Identities = 110/245 (45%), Positives = 155/245 (64%), Gaps = 2/245 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A + Q+ D +L G NWV++T+ + L+D GYPGDR +VLASL ++G +P + A+
Sbjct 3 AGVQQVADGTYLVHGSNTNWVILTEGSSATLVDTGYPGDRDQVLASLAEVGSSPEALTAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DHLGSA + + TPVY H EV HA+RE+ SV V WRP V W
Sbjct 63 LITHAHNDHLGSAEYLRSAYGTPVYLHEAEVPHARREFLHQVSVGTVLKNGWRPGVLPWA 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDA 199
+H +R GG + + QP AE A LPG+P+ + TPGHT GHC++ + GV+ SGD
Sbjct 123 VHAIRVGGTAHVPVTSPQPFPAEGALDLPGRPVPVHTPGHTDGHCAFHLPDRGVVISGDG 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
L++GHP R +GPQLLP +F H + ++ SL A LE +L PGHG ++ GP+R+A +
Sbjct 183 LVSGHPTSRVKGPQLLPDMFHHERARAVASLDVFAQLEGEVLLPGHGPVYRGPVREAALQ 242
Query 260 ALERA 264
A +RA
Sbjct 243 ARDRA 247
>gi|302549091|ref|ZP_07301433.1| beta-lactamase [Streptomyces viridochromogenes DSM 40736]
gi|302466709|gb|EFL29802.1| beta-lactamase [Streptomyces viridochromogenes DSM 40736]
Length=248
Score = 221 bits (562), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 114/245 (47%), Positives = 153/245 (63%), Gaps = 2/245 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A++ + D +L G NWV++T+ V L+D GYPGDR +VLASL ++G +P V A+
Sbjct 3 ADVHHVADGTYLVHGSNTNWVILTEGDAVTLVDTGYPGDREQVLASLAEVGSSPEAVAAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DH+GSA + + TPVY H EV HA+R++ SV V WRP V W
Sbjct 63 LITHAHNDHVGSAEYLRATYGTPVYLHEAEVPHARRDFLHQVSVGTVLRNGWRPGVLPWV 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVV--DGVLASGDA 199
+H LR GG + + T +P A A LPG+P+ + TPGHT GHC+Y V GVL SGDA
Sbjct 123 VHALRSGGTMHNPVTTPEPFPAAGALDLPGRPVPVHTPGHTDGHCAYHVPGTGVLISGDA 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
L++GHP R GPQLLP +F H + ++ SL LA L+ +L PGHG + GP+R A
Sbjct 183 LVSGHPTARIEGPQLLPDMFHHERPRAVASLDVLAELDGELLLPGHGPVHRGPVRDAAHR 242
Query 260 ALERA 264
A ERA
Sbjct 243 ARERA 247
>gi|302556952|ref|ZP_07309294.1| metallo-beta-lactamase superfamily protein [Streptomyces griseoflavus
Tu4000]
gi|302474570|gb|EFL37663.1| metallo-beta-lactamase superfamily protein [Streptomyces griseoflavus
Tu4000]
Length=248
Score = 213 bits (541), Expect = 4e-53, Method: Compositional matrix adjust.
Identities = 111/246 (46%), Positives = 150/246 (61%), Gaps = 2/246 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A + + D +L G NWV++T+ V LID GYPGDRA +LASL ++G P V A+
Sbjct 3 ATVRHVADGTYLVHGTNTNWVILTEGDAVTLIDTGYPGDRAGLLASLAEVGSAPEAVTAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DHLGSA + H TPVY H EV HA+R++ +V V WRP V W
Sbjct 63 LVTHAHSDHLGSAEHLSAAHGTPVYAHEAEVPHARRDFLHQVTVGQVLRNGWRPGVLPWA 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVV--DGVLASGDA 199
H+LR GG + +P A LPG+P+ + TPGHT+GHC++ + GV+ SGDA
Sbjct 123 AHVLRSGGTADVAVTAPRPFPAPGPLDLPGRPVPVHTPGHTAGHCAFHLPGKGVVVSGDA 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
L++GHP R GPQ+L +F H + ++ SL LA L+ ++L PGHG L GP+R A
Sbjct 183 LVSGHPTSRTAGPQMLTDMFHHERATAVASLDVLATLDGDLLLPGHGPLHRGPVRDAALL 242
Query 260 ALERAQ 265
A ERAQ
Sbjct 243 ARERAQ 248
>gi|21225577|ref|NP_631356.1| hypothetical protein SCO7301 [Streptomyces coelicolor A3(2)]
gi|8347034|emb|CAB93739.1| conserved hypothetical protein SC5F8.11c [Streptomyces coelicolor
A3(2)]
Length=248
Score = 208 bits (530), Expect = 7e-52, Method: Compositional matrix adjust.
Identities = 110/245 (45%), Positives = 149/245 (61%), Gaps = 2/245 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A++ Q+ D +L G NWV++TD V L+D GYPGDR +L SL +G +P V A+
Sbjct 3 ADVRQVADGTYLVHGGNTNWVILTDGDAVTLVDTGYPGDRRALLDSLAAVGSSPEAVAAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DHLGSA + H TPV H EV HA+R++ + SV V +WRP V W
Sbjct 63 LITHAHNDHLGSAEYLRTTHGTPVLLHEAEVPHARRDFLQQVSVGTVLRNAWRPGVLPWM 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDA 199
H+LR GG + A+ A LPG+P+ + TPGHT GHC Y + GV+ SGDA
Sbjct 123 RHVLRTGGTEQHPVTAPAAFPADGALDLPGRPVPVHTPGHTDGHCVYHLPDAGVVISGDA 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
L++GH + R GPQLLP +F H + ++ SL +A LE +L PGHG + GP++ A D
Sbjct 183 LVSGHAISRIEGPQLLPDLFHHDRAGAVASLDVIAGLEGEVLLPGHGPVHRGPVKDAADL 242
Query 260 ALERA 264
A ERA
Sbjct 243 ARERA 247
>gi|289767276|ref|ZP_06526654.1| conserved hypothetical protein [Streptomyces lividans TK24]
gi|289697475|gb|EFD64904.1| conserved hypothetical protein [Streptomyces lividans TK24]
Length=248
Score = 208 bits (529), Expect = 7e-52, Method: Compositional matrix adjust.
Identities = 110/245 (45%), Positives = 149/245 (61%), Gaps = 2/245 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A++ Q+ D +L G NWV++TD V L+D GYPGDR +L SL +G +P V A+
Sbjct 3 ADVRQVADGTYLVHGGNTNWVILTDGDAVTLVDTGYPGDRRALLDSLAAVGSSPEAVAAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DHLGSA + H TPV H EV HA+R++ + SV V +WRP V W
Sbjct 63 LITHAHNDHLGSAEYLRTTHGTPVLLHEAEVPHARRDFLQQVSVGTVLRNAWRPGVLPWM 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDA 199
H+LR GG + A+ A LPG+P+ + TPGHT GHC Y + GV+ SGDA
Sbjct 123 RHVLRTGGTEQHPVTEPAAFPADGALDLPGRPVPVHTPGHTDGHCVYHLPDAGVVISGDA 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
L++GH + R GPQLLP +F H + ++ SL +A LE +L PGHG + GP++ A D
Sbjct 183 LVSGHAISRIEGPQLLPDLFHHDRAGAVASLDVIAGLEGEVLLPGHGPVHRGPVKDAADL 242
Query 260 ALERA 264
A ERA
Sbjct 243 ARERA 247
>gi|291441348|ref|ZP_06580738.1| conserved hypothetical protein [Streptomyces ghanaensis ATCC
14672]
gi|291344243|gb|EFE71199.1| conserved hypothetical protein [Streptomyces ghanaensis ATCC
14672]
Length=248
Score = 204 bits (520), Expect = 8e-51, Method: Compositional matrix adjust.
Identities = 108/246 (44%), Positives = 147/246 (60%), Gaps = 2/246 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A++ + D +L G NWV++T+ V LID GYPGDR +L SL ++G++P V A+
Sbjct 3 ADVRHVADGTYLVHGAHTNWVILTEGDAVTLIDTGYPGDRERLLDSLAQVGFSPEAVAAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DHLGSA + TPV+ H EV HA+R++ SV V WRP V W
Sbjct 63 LITHAHTDHLGSAEHLRAAYGTPVHAHEAEVPHARRDFLHQVSVGRVLRNGWRPGVLPWA 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDA 199
+ LR GG + +P LPG+P+ + TPGHT GHC++ + GV+ SGDA
Sbjct 123 LRALRSGGTADVAVAAPEPFPRPGPLDLPGRPVPVPTPGHTDGHCAFHLPRVGVVVSGDA 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDE 259
L++GHP R GP LLP +F H + ++ SL LA LE ++L PGHG L GP+R A
Sbjct 183 LVSGHPTSRIGGPHLLPDMFHHERAAAVASLDVLAELEGDLLLPGHGPLHEGPVRDAARL 242
Query 260 ALERAQ 265
A ERAQ
Sbjct 243 ARERAQ 248
>gi|294634092|ref|ZP_06712647.1| metallo-beta-lactamase superfamily protein [Streptomyces sp.
e14]
gi|292829906|gb|EFF88260.1| metallo-beta-lactamase superfamily protein [Streptomyces sp.
e14]
Length=249
Score = 199 bits (506), Expect = 3e-49, Method: Compositional matrix adjust.
Identities = 105/232 (46%), Positives = 143/232 (62%), Gaps = 5/232 (2%)
Query 26 QITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTH 85
Q+ D +L G NWV++T+ LID GYPGDR +VL SL +G +P V A+++TH
Sbjct 7 QVADGTYLVHGSNTNWVILTEGDAATLIDTGYPGDRQQVLDSLAAVGSSPEAVAAVLITH 66
Query 86 AHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLL 145
AH DHLGSA + + TPV H EV HA+RE+ ++ V WRP V W +H L
Sbjct 67 AHNDHLGSAQYLRETYGTPVRVHEAEVAHARREFLHQVTIGQVLRNGWRPGVLPWAVHAL 126
Query 146 RRGGLTGDGI--PTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALI 201
R GG + + P A P T E LPG+P+ + TPGHT GH + + GV+ SGDAL+
Sbjct 127 RVGGTAHNPVAEPEALPATGE-PLDLPGRPVPVHTPGHTQGHTVFHLPRAGVVVSGDALV 185
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPI 253
+GHP R RGPQLLPA+F H + ++ SL L L+ ++LAPGHG + +GP+
Sbjct 186 SGHPTSRVRGPQLLPAMFHHERARTLASLDILEDLDADVLAPGHGPVHNGPV 237
>gi|318062028|ref|ZP_07980749.1| beta-lactamase domain protein [Streptomyces sp. SA3_actG]
Length=254
Score = 199 bits (505), Expect = 5e-49, Method: Compositional matrix adjust.
Identities = 110/246 (45%), Positives = 147/246 (60%), Gaps = 6/246 (2%)
Query 23 ELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIV 82
++V++ VHL G NWV+V D LID+GYPGDR VLASL +LG P VRA++
Sbjct 9 DVVEVAAGVHLVHGSDTNWVVVKDGDAATLIDSGYPGDRDAVLASLARLGVAPEAVRAVL 68
Query 83 LTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGI 142
+THAH DH+G+A + T V H EEV HA+RE+ ++ + R+WRP V W +
Sbjct 69 ITHAHGDHIGAAEHLRTAYGTDVLMHEEEVPHARREFLHQVTIGKILARAWRPGVLPWAL 128
Query 143 HLLRRGGLTGDGIPTAQP--LTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGD 198
+R GGL +P A P A LPG+P+ + TPGHT GHC+Y + GVL SGD
Sbjct 129 GAVRSGGL--GAVPVAGPRAFPVAGALDLPGRPVPVHTPGHTRGHCAYHLPEHGVLVSGD 186
Query 199 ALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATD 258
AL+TGHP R GPQLLP +F + ++ SLAAL ++ L GHG + G +R+A
Sbjct 187 ALVTGHPTSRLAGPQLLPGMFHTDRARTLASLAALEAIQAGTLLAGHGPVHRGDVREAVA 246
Query 259 EALERA 264
A E A
Sbjct 247 RAREHA 252
>gi|333028937|ref|ZP_08457001.1| hypothetical protein STTU_6441 [Streptomyces sp. Tu6071]
gi|332748789|gb|EGJ79230.1| hypothetical protein STTU_6441 [Streptomyces sp. Tu6071]
Length=254
Score = 198 bits (504), Expect = 6e-49, Method: Compositional matrix adjust.
Identities = 109/246 (45%), Positives = 147/246 (60%), Gaps = 6/246 (2%)
Query 23 ELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIV 82
++V++ VHL G NWV+V D LID+GYPGDR VLASL +LG P VRA++
Sbjct 9 DVVEVAAGVHLVHGSDTNWVVVKDGDAATLIDSGYPGDREAVLASLARLGVAPEAVRAVL 68
Query 83 LTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGI 142
+THAH DH+G+A + T + H EEV HA+RE+ ++ + R+WRP V W +
Sbjct 69 ITHAHGDHIGAAEHLRTAYGTDILMHEEEVPHARREFLHQVTIGKILARAWRPGVLPWAL 128
Query 143 HLLRRGGLTGDGIPTAQP--LTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGD 198
+R GGL +P A P A LPG+P+ + TPGHT GHC+Y + GVL SGD
Sbjct 129 GAVRSGGL--GAVPVAGPRAFPVAGALDLPGRPVPVHTPGHTRGHCAYHLPEHGVLVSGD 186
Query 199 ALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATD 258
AL+TGHP R GPQLLP +F + ++ SLAAL ++ L GHG + G +R+A
Sbjct 187 ALVTGHPTSRLAGPQLLPGMFHADRARTLASLAALEAIQAGTLLAGHGPVHRGDVREAVA 246
Query 259 EALERA 264
A E A
Sbjct 247 RAREHA 252
>gi|126348089|emb|CAJ89810.1| putative beta-lactamase [Streptomyces ambofaciens ATCC 23877]
Length=248
Score = 197 bits (501), Expect = 1e-48, Method: Compositional matrix adjust.
Identities = 100/234 (43%), Positives = 144/234 (62%), Gaps = 2/234 (0%)
Query 22 AELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAI 81
A++ + + +HL G NWV++ + V L+D GYPGDR ++LASL ++G P V A+
Sbjct 3 AQVRHVGEGIHLVHGSHTNWVILREGDAVTLVDTGYPGDREQLLASLAEVGSAPEAVVAV 62
Query 82 VLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWG 141
++THAH DHLGSA + H TPV H EV HA+R++ + +V V +WRP V W
Sbjct 63 LITHAHSDHLGSAEYLRAAHGTPVLLHDAEVPHARRDFLQQVTVARVLRNAWRPGVLPWA 122
Query 142 IHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDA 199
+H+LR GG + + +P LPG+P+ + TPGHT GHC+Y + GV+ SGDA
Sbjct 123 VHVLRSGGTERHPVSSPEPFPTAGPLDLPGRPVPVHTPGHTDGHCAYHLPDAGVVISGDA 182
Query 200 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPI 253
L++GH R GPQLLP +F H + ++ SL LA L+ ++L PGHG GP+
Sbjct 183 LVSGHATSRVAGPQLLPGMFHHDRARAVASLDVLAGLDGDVLLPGHGPPHRGPM 236
>gi|329935776|ref|ZP_08285580.1| hypothetical protein SGM_1072 [Streptomyces griseoaurantiacus
M045]
gi|329304767|gb|EGG48641.1| hypothetical protein SGM_1072 [Streptomyces griseoaurantiacus
M045]
Length=257
Score = 195 bits (496), Expect = 5e-48, Method: Compositional matrix adjust.
Identities = 109/233 (47%), Positives = 145/233 (63%), Gaps = 6/233 (2%)
Query 23 ELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIV 82
++V+I + VH RG NWV+V + +LID GYPGDR +LASL + PG + A++
Sbjct 9 DVVRIDEHVHAVRGGDTNWVIVKEGDSAVLIDTGYPGDRERLLASLAAVAVAPGALAAVL 68
Query 83 LTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGI 142
+THAH DHLGSA H TPV H +EV HA+R++ SV V R+WRP VA W +
Sbjct 69 VTHAHNDHLGSAERLRAAHGTPVLMHEDEVPHARRDFLHQVSVGQVLARAWRPGVAPWAL 128
Query 143 HLLRRGGLTGDGIPTAQP--LTAEAAAGLPGQPMAIFTPGHTSGHCSYVV--DGVLASGD 198
LR GG +P A P A+ LPG P+ + +PGHT GHC+Y++ GVL SGD
Sbjct 129 RALRAGGTAH--LPVADPRAFPADGPLDLPGAPVPVHSPGHTRGHCAYLLPRSGVLVSGD 186
Query 199 ALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHG 251
AL+TGHP R RGPQLLP +F + + SLAAL ++ ++L PGHG + HG
Sbjct 187 ALVTGHPTSRTRGPQLLPGMFHADRARARDSLAALEAVDADVLVPGHGPVHHG 239
>gi|111024903|ref|YP_707323.1| beta-lactamase [Rhodococcus jostii RHA1]
gi|110823882|gb|ABG99165.1| possible beta-lactamase [Rhodococcus jostii RHA1]
Length=251
Score = 187 bits (474), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 100/233 (43%), Positives = 133/233 (58%), Gaps = 2/233 (0%)
Query 23 ELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIV 82
+ V+I D V VNWVL+TD V +ID GYPG R V S+ +G P + A++
Sbjct 4 QTVEIADGVFFVHSEMVNWVLLTDGDAVSVIDTGYPGQRGAVEESIRAIGRDPHGIEAVL 63
Query 83 LTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGI 142
+THAH+DH+GSA + + + PV H +EV HA+RE E A+ +DV WRP V W I
Sbjct 64 ITHAHVDHIGSAQYLSDTYGAPVLVHPDEVAHARRECHEVATPWDVLGNIWRPGVLPWAI 123
Query 143 HLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDAL 200
L+R GG GI + P+ A PG P+ + PGHTSGH Y + GV+ SGDAL
Sbjct 124 KLIRLGGTAKYGIDSPTPMPVPGALTCPGAPVPVLAPGHTSGHTIYHLPDRGVVISGDAL 183
Query 201 ITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPI 253
ITGH GPQLLP F H + + SL + L+ +IL PGHG + G +
Sbjct 184 ITGHLTSPISGPQLLPQWFDHDRGTATESLRIIGELDADILLPGHGPIHRGSV 236
>gi|111026302|ref|YP_708585.1| hypothetical protein RHA1_ro10234 [Rhodococcus jostii RHA1]
gi|110825145|gb|ABH00427.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=249
Score = 186 bits (473), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 99/231 (43%), Positives = 132/231 (58%), Gaps = 2/231 (0%)
Query 25 VQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLT 84
V+I D V VNWVL+TD + +ID GYPG R EV S+ +G P + A+++T
Sbjct 4 VEIADGVFFVHSEMVNWVLLTDGDALTVIDTGYPGQRGEVEESIRAIGRDPHGIEAVLIT 63
Query 85 HAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHL 144
HAH+DH+GSA + + PV H +EV HA+R+ E A+ +DV W P V W I L
Sbjct 64 HAHVDHIGSAQYLGDTYGAPVLVHPDEVAHARRDCHEVATPWDVLSNIWAPGVLPWAIKL 123
Query 145 LRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALIT 202
+R GG GI + P+ A PG P+ + PGHTSGH Y + GV+ SGDALIT
Sbjct 124 IRLGGTAKYGIDSPTPMPVPGALTCPGAPVPVLAPGHTSGHTIYHLPERGVVISGDALIT 183
Query 203 GHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPI 253
GH R GPQLLP F H + + SL + L+ +IL PGHG + G +
Sbjct 184 GHLTSRVSGPQLLPQWFDHDRGTAAESLRIIGELDADILLPGHGPIHRGSV 234
>gi|256389447|ref|YP_003111011.1| beta-lactamase domain-containing protein [Catenulispora acidiphila
DSM 44928]
gi|256355673|gb|ACU69170.1| beta-lactamase domain protein [Catenulispora acidiphila DSM 44928]
Length=252
Score = 185 bits (469), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 100/236 (43%), Positives = 135/236 (58%), Gaps = 6/236 (2%)
Query 32 HLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHL 91
H G V WV+V D LID GYP D +LASL LG P + AI++THAH DH+
Sbjct 18 HAVLGSDVTWVVVKDGDAATLIDTGYPQDYDNLLASLALLGVAPESLSAILITHAHNDHI 77
Query 92 GSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLT 151
G A + PV HAEEV HA+R++ + S+ VA +WRP V W + LR GG T
Sbjct 78 GGAERLRSTYGIPVLTHAEEVPHARRDFLDQVSIGKVAANAWRPGVVPWALRALRSGG-T 136
Query 152 GDGIPTAQP--LTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALITGHPML 207
D +P A+P A+ LPG P+ + TPGHT GHC+Y++ G+L GDAL TGHP
Sbjct 137 AD-VPVAEPQAFPADGPLDLPGAPIPLHTPGHTEGHCAYLLPAAGILVCGDALGTGHPTS 195
Query 208 RHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALER 263
R GPQ+LP +F + ++ SL+ ++ ++L PGHG + G +R ER
Sbjct 196 RISGPQMLPTMFQKDRARALASLSVFEGIDADVLVPGHGPVHRGAMRDVVQRVRER 251
>gi|296139003|ref|YP_003646246.1| beta-lactamase [Tsukamurella paurometabola DSM 20162]
gi|296027137|gb|ADG77907.1| beta-lactamase domain protein [Tsukamurella paurometabola DSM
20162]
Length=242
Score = 182 bits (461), Expect = 7e-44, Method: Compositional matrix adjust.
Identities = 104/243 (43%), Positives = 142/243 (59%), Gaps = 7/243 (2%)
Query 26 QITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTH 85
++ V G VN++ + D V LIDAG+ GD V A L +G P DVRAI++TH
Sbjct 3 ELERGVWFGAGTHVNFLALVDGDDVTLIDAGWTGDADRVEAELASIGRRPQDVRAILVTH 62
Query 86 AHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLL 145
AHIDH+G A H PV H +E+ HA+ E E A+ D+ +WRPR W +
Sbjct 63 AHIDHVGGAAALHERHGIPVLAHPDELAHARGETHEQATPLDILPIAWRPRTLRWMADVA 122
Query 146 RRGGLTGDGIPTAQPLT--AEAAAGLPGQPMAIFTPGHTSGHCSYVVD-GVLASGDALIT 202
R G L+ +P AQ + ++ A LPG PM + PGHTSGH ++ + GV+A+GDAL+T
Sbjct 123 RVGVLSHVAMPYAQAFSPGSDTALDLPGAPMPVACPGHTSGHTAFALPGGVVATGDALVT 182
Query 203 GHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALE 262
GHP+ GPQLLP FSH +I +L A+A L+ +LAPGHG W R + EA+
Sbjct 183 GHPLSATTGPQLLPEFFSHDVPRTIATLDAIATLDAGLLAPGHGAPW----RGSPAEAVA 238
Query 263 RAQ 265
RA+
Sbjct 239 RAR 241
>gi|111017777|ref|YP_700749.1| beta lactamase [Rhodococcus jostii RHA1]
gi|110817307|gb|ABG92591.1| probable beta lactamase [Rhodococcus jostii RHA1]
Length=327
Score = 174 bits (442), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 96/228 (43%), Positives = 127/228 (56%), Gaps = 2/228 (0%)
Query 26 QITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTH 85
+I + V VNWVL+T+ V +ID GYPG R EV S+ +G P + A+++TH
Sbjct 83 EIAEGVFFVHSEMVNWVLLTEGDAVTVIDTGYPGQRGEVEESIRAIGRDPHGIEAVLITH 142
Query 86 AHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLL 145
AH+DH+GSA + A + PV H E HA+RE E A+ +DV RP V W + L+
Sbjct 143 AHVDHIGSAQYLAETYGAPVLVHPAEAAHARRECHEVATPWDVLSNIGRPGVLSWAMKLV 202
Query 146 RRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALITG 203
R GG GI + P+ A PG P+ + PGHTSGH Y + GV+ SGDALITG
Sbjct 203 RLGGTAKYGIDSPTPMPVLGALTCPGAPVPVLVPGHTSGHTVYHLPDHGVVISGDALITG 262
Query 204 HPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHG 251
HP GPQLLP +H + SL + L +IL PGHG + G
Sbjct 263 HPTSPISGPQLLPQWLNHYYGTAAVSLDIIGELGADILLPGHGPIHRG 310
>gi|119964472|ref|YP_947179.1| metallo-beta-lactamase superfamily protein [Arthrobacter aurescens
TC1]
gi|119951331|gb|ABM10242.1| metallo-beta-lactamase superfamily protein [Arthrobacter aurescens
TC1]
Length=243
Score = 172 bits (437), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 86/228 (38%), Positives = 133/228 (59%), Gaps = 2/228 (0%)
Query 31 VHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDH 90
VH G A NW++V D +G +LID GYP DR VL S+ LG P D +A+++TH H+DH
Sbjct 10 VHFVEGPASNWLIVRDASGFMLIDGGYPADRELVLESIRGLGLDPADAKAMLITHGHVDH 69
Query 91 LGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL 150
GSA +F+R TP+ C EE+ H + + + + V +R+WRP V W +H+++ L
Sbjct 70 TGSAAYFSRTFGTPILCSPEELAHVQGKEKHQVTFGQVLVRAWRPTVFRWMLHVIKAKAL 129
Query 151 TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALITGHPMLR 208
+ A+ T E LPGQP AI PGHT G+ + ++ G +A GD+ ++GHP+
Sbjct 130 QAEPATHAEAWTPEKLKDLPGQPQAILLPGHTPGNVALLLPTAGAIAVGDSFVSGHPIST 189
Query 209 HRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKA 256
GPQ+L ++ ++ S +LA ++ ++ PGHG H P+ +A
Sbjct 190 TSGPQMLHRMYHSDPAAALASARSLAAVQAKVILPGHGTALHMPLTEA 237
>gi|219882988|ref|YP_002478152.1| beta-lactamase domain protein [Arthrobacter chlorophenolicus
A6]
gi|219861994|gb|ACL42335.1| beta-lactamase domain protein [Arthrobacter chlorophenolicus
A6]
Length=258
Score = 172 bits (436), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 88/228 (39%), Positives = 131/228 (58%), Gaps = 2/228 (0%)
Query 31 VHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDH 90
V G A NW++V+DD+G +LID GYP D + VL S+ +G+ PGD +A+++TH H+DH
Sbjct 25 VFFVEGPASNWIIVSDDSGFILIDGGYPEDASLVLRSIWHVGFKPGDAKAVLITHGHVDH 84
Query 91 LGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL 150
LGSA F+ + TPV E+ H + + + ++ L +WRP V W H + G L
Sbjct 85 LGSAAHFSEAYGTPVLTSPAELAHVQGKEKHQVTLATCILNAWRPGVFSWLKHAISAGAL 144
Query 151 TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALITGHPMLR 208
+ + A+ T E LPGQP I PGHT GH ++ G + +GDALITGH + R
Sbjct 145 SPKPVAAAEAWTPERLRELPGQPQPISVPGHTPGHAVILLPKAGAIVTGDALITGHSLSR 204
Query 209 HRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKA 256
H GPQ+L A++ ++ + AL +E +++ PGHG P+ A
Sbjct 205 HTGPQMLDAMYHTDADEALAATHALDNVEASLILPGHGPALKMPLSDA 252
>gi|326384285|ref|ZP_08205966.1| beta-lactamase domain-containing protein [Gordonia neofelifaecis
NRRL B-59395]
gi|326196883|gb|EGD54076.1| beta-lactamase domain-containing protein [Gordonia neofelifaecis
NRRL B-59395]
Length=250
Score = 172 bits (436), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 98/236 (42%), Positives = 136/236 (58%), Gaps = 4/236 (1%)
Query 30 KVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHID 89
+ HL VNWV++ D GV L+D GYPG V SL ++G +V+A +LTHAH+D
Sbjct 15 RTHLVHTRYVNWVILQSDDGVTLVDGGYPGHADAVAESLRRVGSDLSEVQAALLTHAHVD 74
Query 90 HLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGG 149
HLG R S PVY EV HA+R++ E A +A ++RPRV W ++R G
Sbjct 75 HLGGLAQIGRTRSFPVYADPAEVAHARRDFLEQADASTIAPIAYRPRVMRWLPGVVRLGA 134
Query 150 LTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVV-DG-VLASGDALITGHPML 207
L GI QPL + LPG P A+ TPGHT GH +++ DG V+ +GDALI+ HP
Sbjct 135 LDKAGIGDTQPLGDLSF--LPGAPKAVPTPGHTRGHSAFLAGDGEVVITGDALISAHPTT 192
Query 208 RHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALER 263
+ RGPQ L VF+H + ++A+L L+ ++ PGHG + G + D+AL R
Sbjct 193 KRRGPQCLDHVFTHDVAANEAAVASLRDLDAVVVMPGHGPMLCGRVGAFVDQALSR 248
>gi|262200279|ref|YP_003271487.1| beta-lactamase [Gordonia bronchialis DSM 43247]
gi|262083626|gb|ACY19594.1| beta-lactamase domain protein [Gordonia bronchialis DSM 43247]
Length=248
Score = 169 bits (428), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 92/234 (40%), Positives = 132/234 (57%), Gaps = 4/234 (1%)
Query 32 HLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHL 91
HL AVNWV++ + + + LID GYPG + V++S+ +G P D+R +LTHAH+DHL
Sbjct 17 HLVTTGAVNWVILREGSDLTLIDGGYPGQASTVVSSIRAIGAQPEDIRGALLTHAHVDHL 76
Query 92 GSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLT 151
G R + VY EV HA+R++ + A V D+A ++RPRV W + G L+
Sbjct 77 GGLAKLQRRYGFDVYMDPVEVAHARRDHLQQADVRDIAPIAYRPRVLKWLAMVTPLGVLS 136
Query 152 GDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG--VLASGDALITGHPMLRH 209
G+P AQP LPG+P + GHT GH +Y+ G VL SGDAL++GHP+
Sbjct 137 RAGLPDAQPF--PDPLDLPGRPTPVAAHGHTDGHSAYLAAGGAVLVSGDALVSGHPISTI 194
Query 210 RGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALER 263
GPQ + F H + R++ A L+ +L PGHG + GP+ A AL+
Sbjct 195 TGPQCISDAFQHDVDEARRTVDAFTRLDATVLFPGHGPIHRGPVALAAQHALDN 248
>gi|312139961|ref|YP_004007297.1| metallo-beta-lactamase superfamily protein [Rhodococcus equi
103S]
gi|311889300|emb|CBH48615.1| putative metallo-beta-lactamase superfamily protein [Rhodococcus
equi 103S]
Length=252
Score = 164 bits (416), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 94/251 (38%), Positives = 141/251 (57%), Gaps = 3/251 (1%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
M + ++ V G VN+VL+ D + LID GYPGD A V ++ LG P DV+
Sbjct 1 MTTVEEVAPDVFRGSGTHVNFVLLRDGDALTLIDGGYPGDVAAVDGAIRSLGRRPEDVQG 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVW 140
++LTHAH+DH+G+ + F + PV+ EV HA+R+Y E A+ D R V W
Sbjct 61 MLLTHAHVDHMGAIVSFHERYGIPVFTDPTEVAHARRDYLEQATGKDFIPMLHRHGVLPW 120
Query 141 GIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGD 198
+ + R G + AQ +T+ LPG P+ + T GHTSGH ++ + GV+ +GD
Sbjct 121 LLRIARAGATRSVSV-NAQAVTSGRPLDLPGGPVPVATHGHTSGHTAFHLPQHGVVVTGD 179
Query 199 ALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATD 258
AL+T HP+ + +GPQLLP VF H +++ +L LA L+ + + PGHG + I A D
Sbjct 180 ALVTAHPLSKTQGPQLLPPVFDHGHGDTLAALDHLAGLDADTVLPGHGPVVSTAIAAAVD 239
Query 259 EALERAQKSNH 269
+A E A+ +
Sbjct 240 QAREAARSREY 250
>gi|325674150|ref|ZP_08153839.1| metallo-beta-lactamase superfamily protein [Rhodococcus equi
ATCC 33707]
gi|325554830|gb|EGD24503.1| metallo-beta-lactamase superfamily protein [Rhodococcus equi
ATCC 33707]
Length=252
Score = 160 bits (406), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 94/252 (38%), Positives = 142/252 (57%), Gaps = 5/252 (1%)
Query 21 MAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRA 80
M + ++ V G VN+VL+ D + LID GYPGD A V ++ LG P DV+
Sbjct 1 MTTVEEVAPDVFRGSGTHVNFVLLRDGDALTLIDGGYPGDVAAVDGAIRSLGRRPEDVQG 60
Query 81 IVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFD-VALRSWRPRVAV 139
++LTHAH+DH+G+ + F + PV+ EV HA+R+Y E A+ D + + W V
Sbjct 61 MLLTHAHVDHMGAIVSFHERYGIPVFTDPTEVAHARRDYLEQATGKDFIPMLHWH-GVLP 119
Query 140 WGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASG 197
W + + R G + AQ +T+ LPG P+ + T GHTSGH ++ + GV+ +G
Sbjct 120 WLLRIARAGATRSVSV-NAQAVTSGRPLDLPGGPVPVATHGHTSGHTAFHLPQHGVVVTG 178
Query 198 DALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKAT 257
DAL+T HP+ + +GPQLLP VF H +++ +L LA L+ + + PGHG + I A
Sbjct 179 DALVTAHPLSKTQGPQLLPPVFDHGHGDTLAALDHLAGLDADTVLPGHGPVVSMAIAAAV 238
Query 258 DEALERAQKSNH 269
D A E A+ +
Sbjct 239 DLACEAARSREY 250
>gi|229488995|ref|ZP_04382861.1| beta-lactamase domain protein [Rhodococcus erythropolis SK121]
gi|229324499|gb|EEN90254.1| beta-lactamase domain protein [Rhodococcus erythropolis SK121]
Length=254
Score = 159 bits (403), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 94/239 (40%), Positives = 133/239 (56%), Gaps = 3/239 (1%)
Query 24 LVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVL 83
+ QI + HL R NWVLV + + + LID GYP + +V S+ ++G+ GDVRAI++
Sbjct 8 ITQI-ENTHLVRCGHANWVLVEEGSDLTLIDGGYPANGTDVERSIEQIGHQLGDVRAILV 66
Query 84 THAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIH 143
THAHIDH+G PV EV HAKREY + S V L WR W
Sbjct 67 THAHIDHIGGIADIVTRLEVPVLMDPLEVPHAKREYLQQLSPAGVPLLLWRRGAPKWLRD 126
Query 144 LLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALI 201
++ G L G +P AQ + A +PG+ + I T GHT GH +Y+V GV+ASGDAL+
Sbjct 127 VIGVGALKGAELPRAQSFASGGALDVPGRIVPIPTHGHTDGHSAYLVPDAGVIASGDALV 186
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 260
TGH GPQ L F+H ++ + ++L +A +L PGHG ++ G + A ++A
Sbjct 187 TGHATSSVAGPQFLVCPFNHDREATDQALDNIAAAPAGVLFPGHGPVYEGSMTAAVEQA 245
>gi|308177387|ref|YP_003916793.1| metallo-beta-lactamase [Arthrobacter arilaitensis Re117]
gi|307744850|emb|CBT75822.1| metallo-beta-lactamase superfamily protein [Arthrobacter arilaitensis
Re117]
Length=251
Score = 159 bits (402), Expect = 4e-37, Method: Compositional matrix adjust.
Identities = 89/234 (39%), Positives = 131/234 (56%), Gaps = 2/234 (0%)
Query 32 HLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHL 91
++ G A NW+++ D+ +ID GYPGD VL S+ +LG + D A+++TH H+DH
Sbjct 15 YMVEGPASNWIILEDNGVYTVIDGGYPGDVPLVLDSIRRLGLSVKDAAAMLITHGHVDHT 74
Query 92 GSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLT 151
G+A +FA E PV E E R S + +R+W+PRV W H+L GG
Sbjct 75 GAAAYFASELCVPVLSSHAEHTQMTGEERFQVSPVQILVRAWQPRVFKWMRHVLTVGGTE 134
Query 152 GDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG--VLASGDALITGHPMLRH 209
G + A+ T + A LPG P+A+ TPGHT GH ++ + VL SGDALI+GH +
Sbjct 135 GTKVLEAKIWTTQQLAALPGAPVAVPTPGHTPGHSAFHLPDAKVLISGDALISGHALSTT 194
Query 210 RGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALER 263
G Q+L +F H +Q + ++L A L+ + + PGHG+ H +A AL R
Sbjct 195 TGAQMLHPMFHHERQQAYQALTAFDGLDADSILPGHGKALHCQPAEAVHAALAR 248
>gi|226308338|ref|YP_002768298.1| beta-lactamase [Rhodococcus erythropolis PR4]
gi|226187455|dbj|BAH35559.1| putative beta-lactamase [Rhodococcus erythropolis PR4]
Length=254
Score = 158 bits (399), Expect = 9e-37, Method: Compositional matrix adjust.
Identities = 92/234 (40%), Positives = 128/234 (55%), Gaps = 2/234 (0%)
Query 29 DKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHI 88
+ HL R NWVLV + + LID GYP + +V S+ ++G+ GDVRAI++THAH+
Sbjct 12 ENTHLVRCGHANWVLVEEGADLTLIDGGYPANGTDVERSIEQIGHQLGDVRAILVTHAHV 71
Query 89 DHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRG 148
DH+G PV EV HAKREY + S V L WR W + ++ G
Sbjct 72 DHIGGIADIVTRLQVPVLMDPLEVPHAKREYLQQLSPAKVPLLLWRRGAPKWLLDVIGAG 131
Query 149 GLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVD--GVLASGDALITGHPM 206
L G +P AQ A A +PG+ + I T GHT GH +Y+V GV+ASGDAL+TGH
Sbjct 132 ALKGAELPRAQAFAAGGALDVPGRIVPIPTHGHTDGHSAYLVPEAGVIASGDALVTGHAT 191
Query 207 LRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEA 260
GPQ L F+H + + ++L +A L PGHG ++ G + A ++A
Sbjct 192 SSVAGPQFLVCPFNHDRGATDQALDNIAAAPAGALFPGHGPVYEGSLAAAVEQA 245
>gi|343926198|ref|ZP_08765707.1| putative beta-lactamase [Gordonia alkanivorans NBRC 16433]
gi|343763827|dbj|GAA12633.1| putative beta-lactamase [Gordonia alkanivorans NBRC 16433]
Length=255
Score = 150 bits (380), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 87/225 (39%), Positives = 124/225 (56%), Gaps = 4/225 (1%)
Query 39 VNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFA 98
VNWVL+ + + LID GYPG +V+ S+N++G P D+R +LTHAH+DHLG
Sbjct 31 VNWVLLEQNGELTLIDGGYPGQAGQVIESINRIGRRPEDIRGALLTHAHVDHLGGLAKLQ 90
Query 99 REHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTA 158
+ PVY EV HA R + + A+ D+A + R+ W G L+ G+P A
Sbjct 91 ARYGFPVYMDPVEVDHALRHHLQQANALDLAPLAGHRRLWSWLAKTTPLGVLSRAGLPAA 150
Query 159 QPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVV-DG-VLASGDALITGHPMLRHRGPQLLP 216
P + LPG P+ + + GHT GH SY+V DG L SGDAL++GH + GPQ +P
Sbjct 151 APFS--EPLDLPGSPIPVASHGHTDGHSSYLVGDGRALVSGDALVSGHEVSAIAGPQCIP 208
Query 217 AVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEAL 261
+ F H + + RS+ L+ +L GHG L+ G + A AL
Sbjct 209 SPFQHDEATARRSVERFIELDAELLLAGHGPLYRGSVADAALRAL 253
>gi|238494956|ref|XP_002378714.1| conserved hypothetical protein [Aspergillus flavus NRRL3357]
gi|220695364|gb|EED51707.1| conserved hypothetical protein [Aspergillus flavus NRRL3357]
Length=249
Score = 150 bits (379), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 88/246 (36%), Positives = 136/246 (56%), Gaps = 4/246 (1%)
Query 24 LVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVL 83
+ ++ V VN ++ + + + LID G+PGD + + + +G P DVRAI+L
Sbjct 1 MTEVAPNVFCISVTDVNVTVLREGSDLTLIDGGWPGDVSTIENVIRSIGNRPEDVRAILL 60
Query 84 THAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIH 143
THAHIDHLG+ F + P+Y E+ HA R Y E A+ D+ ++ P+ W
Sbjct 61 THAHIDHLGAVQSFHDRLNVPIYSDPIEIRHAARYYLEQAAEADI-MKGPMPQTLDWWER 119
Query 144 LLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG--VLASGDALI 201
+L+ G T I QP+ A +PG+P+AI T GHTSGH ++ V + +GD L+
Sbjct 120 VLKVGADTDITITDVQPV-ASGQLDVPGRPVAIATHGHTSGHSAFYVPAARTVITGDCLV 178
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEAL 261
TGH GPQ P F+HS ++ +L L ++ +I+ PGHG+ + PI +A D AL
Sbjct 179 TGHACSTIEGPQPCPWFFNHSIPEALSALKVLKSVDADIIIPGHGQPLNMPISQAVDIAL 238
Query 262 ERAQKS 267
+ A++S
Sbjct 239 KVAEES 244
>gi|169777739|ref|XP_001823335.1| hypothetical protein AOR_1_912114 [Aspergillus oryzae RIB40]
gi|83772072|dbj|BAE62202.1| unnamed protein product [Aspergillus oryzae RIB40]
Length=249
Score = 147 bits (372), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 88/246 (36%), Positives = 135/246 (55%), Gaps = 4/246 (1%)
Query 24 LVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVL 83
+ ++ V VN ++ + + + LID G+PGD + + + +G P DVRAI+L
Sbjct 1 MTEVAPNVFCISVTDVNATVLREGSDLTLIDGGWPGDVSTIENVIRSIGNRPEDVRAILL 60
Query 84 THAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIH 143
THAHIDHLG+ F + P+Y E+ HA R Y E A+ D+ ++ P+ W
Sbjct 61 THAHIDHLGAVQSFHDRLNVPIYSDPIEIRHAARYYLEQAAEADI-MKGPMPQTLGWWER 119
Query 144 LLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG--VLASGDALI 201
+L+ G T I QP+ A +PG+P+AI T GHTSGH ++ V + +GD L+
Sbjct 120 VLKVGADTDITITDVQPV-ASGQLDVPGRPVAIATHGHTSGHSAFYVPAARTVITGDCLV 178
Query 202 TGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEAL 261
TGH GPQ P F+HS + +L L ++ +I+ PGHG+ + PI +A D AL
Sbjct 179 TGHACSTIEGPQPCPWFFNHSIPEAHSALKVLKSVDADIIIPGHGQPLNMPISQAVDIAL 238
Query 262 ERAQKS 267
+ A++S
Sbjct 239 KVAEES 244
Lambda K H
0.321 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 423010730970
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40