BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0414c
Length=222
Score E
Sequences producing significant alignments: (Bits) Value
gi|345100736|pdb|3O63|A Chain A, Crystal Structure Of Thiamin Ph... 433 7e-120
gi|15607555|ref|NP_214928.1| thiamine-phosphate pyrophosphorylas... 431 3e-119
gi|340625439|ref|YP_004743891.1| putative thiamine-phosphate pyr... 430 7e-119
gi|289748898|ref|ZP_06508276.1| thiamine-phosphate pyrophosphory... 414 7e-114
gi|254818979|ref|ZP_05223980.1| thiamine-phosphate pyrophosphory... 338 3e-91
gi|289756483|ref|ZP_06515861.1| thiamin-phosphate pyrophosphoryl... 336 1e-90
gi|118465379|ref|YP_883874.1| thiamine-phosphate pyrophosphoryla... 320 9e-86
gi|41409995|ref|NP_962831.1| thiamine-phosphate pyrophosphorylas... 314 7e-84
gi|296167872|ref|ZP_06850055.1| thiamin-phosphate pyrophosphoryl... 313 2e-83
gi|336460362|gb|EGO39262.1| thiamine-phosphate pyrophosphorylase... 311 5e-83
gi|342859106|ref|ZP_08715760.1| thiamine-phosphate pyrophosphory... 308 4e-82
gi|254777186|ref|ZP_05218702.1| thiamine-phosphate pyrophosphory... 303 1e-80
gi|15827073|ref|NP_301336.1| thiamine-phosphate pyrophosphorylas... 299 2e-79
gi|118467945|ref|YP_885195.1| thiamine-phosphate pyrophosphoryla... 298 4e-79
gi|126433146|ref|YP_001068837.1| thiamine-phosphate pyrophosphor... 290 1e-76
gi|240168880|ref|ZP_04747539.1| thiamine-phosphate pyrophosphory... 287 6e-76
gi|145220803|ref|YP_001131481.1| thiamine-phosphate pyrophosphor... 287 7e-76
gi|120401722|ref|YP_951551.1| thiamine-phosphate pyrophosphoryla... 286 1e-75
gi|108797524|ref|YP_637721.1| thiamine-phosphate pyrophosphoryla... 281 4e-74
gi|333989025|ref|YP_004521639.1| thiamine-phosphate pyrophosphor... 280 8e-74
gi|315442244|ref|YP_004075123.1| thiamine-phosphate diphosphoryl... 278 6e-73
gi|183980740|ref|YP_001849031.1| thiamine-phosphate pyrophosphor... 275 4e-72
gi|118618240|ref|YP_906572.1| thiamine-phosphate pyrophosphoryla... 275 4e-72
gi|312141234|ref|YP_004008570.1| thiamine phosphate pyrophosphor... 271 7e-71
gi|54027314|ref|YP_121556.1| thiamine-phosphate pyrophosphorylas... 268 3e-70
gi|302530628|ref|ZP_07282970.1| thiamine-phosphate pyrophosphory... 267 1e-69
gi|333918210|ref|YP_004491791.1| Thiamine-phosphate pyrophosphor... 265 4e-69
gi|229493086|ref|ZP_04386881.1| thiamine-phosphate pyrophosphory... 263 9e-69
gi|169631297|ref|YP_001704946.1| thiamine-phosphate pyrophosphor... 263 1e-68
gi|226304968|ref|YP_002764926.1| thiamine-phosphate pyrophosphor... 263 2e-68
gi|111019184|ref|YP_702156.1| thiamine-phosphate pyrophosphoryla... 259 1e-67
gi|226361320|ref|YP_002779098.1| thiamine-phosphate pyrophosphor... 258 4e-67
gi|294628869|ref|ZP_06707429.1| thiamine-phosphate pyrophosphory... 254 8e-66
gi|324998504|ref|ZP_08119616.1| thiamine-phosphate pyrophosphory... 253 2e-65
gi|257057424|ref|YP_003135256.1| thiamine-phosphate pyrophosphor... 250 1e-64
gi|29832641|ref|NP_827275.1| thiamine-phosphate pyrophosphorylas... 246 1e-63
gi|41018323|sp|Q82AF9.2|THIE_STRAW RecName: Full=Thiamine-phosph... 246 2e-63
gi|331699486|ref|YP_004335725.1| Thiamine-phosphate pyrophosphor... 245 3e-63
gi|343924497|ref|ZP_08764046.1| thiamine-phosphate pyrophosphory... 243 1e-62
gi|254382616|ref|ZP_04997974.1| thiamine-phosphate pyrophosphory... 241 8e-62
gi|326384629|ref|ZP_08206307.1| thiamine-phosphate pyrophosphory... 240 1e-61
gi|256395128|ref|YP_003116692.1| thiamine-phosphate pyrophosphor... 239 2e-61
gi|329940963|ref|ZP_08290243.1| thiamin phosphate pyrophosphoryl... 238 6e-61
gi|297199084|ref|ZP_06916481.1| thiamine-phosphate pyrophosphory... 235 3e-60
gi|297562055|ref|YP_003681029.1| thiamine-phosphate pyrophosphor... 235 4e-60
gi|291444029|ref|ZP_06583419.1| thiamine-phosphate pyrophosphory... 234 5e-60
gi|302561103|ref|ZP_07313445.1| thiamine-phosphate pyrophosphory... 234 6e-60
gi|72161450|ref|YP_289107.1| thiamine-phosphate pyrophosphorylas... 234 7e-60
gi|300790385|ref|YP_003770676.1| thiamine-phosphate pyrophosphor... 234 7e-60
gi|302533974|ref|ZP_07286316.1| thiamine-phosphate pyrophosphory... 234 1e-59
>gi|345100736|pdb|3O63|A Chain A, Crystal Structure Of Thiamin Phosphate Synthase From
Mycobacterium Tuberculosis
gi|345100737|pdb|3O63|B Chain B, Crystal Structure Of Thiamin Phosphate Synthase From
Mycobacterium Tuberculosis
Length=243
Score = 433 bits (1114), Expect = 7e-120, Method: Compositional matrix adjust.
Identities = 221/222 (99%), Positives = 222/222 (100%), Gaps = 0/222 (0%)
Query 1 VHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
+HESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE
Sbjct 22 MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 81
Query 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS
Sbjct 82 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 141
Query 121 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN 180
THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN
Sbjct 142 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN 201
Query 181 AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
Sbjct 202 AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 243
>gi|15607555|ref|NP_214928.1| thiamine-phosphate pyrophosphorylase [Mycobacterium tuberculosis
H37Rv]
gi|15839800|ref|NP_334837.1| thiamine-phosphate pyrophosphorylase [Mycobacterium tuberculosis
CDC1551]
gi|31791592|ref|NP_854085.1| thiamine-phosphate pyrophosphorylase [Mycobacterium bovis AF2122/97]
76 more sequence titles
Length=222
Score = 431 bits (1109), Expect = 3e-119, Method: Compositional matrix adjust.
Identities = 221/222 (99%), Positives = 222/222 (100%), Gaps = 0/222 (0%)
Query 1 VHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
+HESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE
Sbjct 1 MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
Query 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS
Sbjct 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
Query 121 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN 180
THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN
Sbjct 121 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN 180
Query 181 AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
Sbjct 181 AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
>gi|340625439|ref|YP_004743891.1| putative thiamine-phosphate pyrophosphorylase [Mycobacterium
canettii CIPT 140010059]
gi|340003629|emb|CCC42752.1| putative thiamine-phosphate pyrophosphorylase THIE (TMP pyrophosphorylase)
(TMP-PPASE) (thiamine-phosphate synthase) [Mycobacterium
canettii CIPT 140010059]
Length=222
Score = 430 bits (1106), Expect = 7e-119, Method: Compositional matrix adjust.
Identities = 220/222 (99%), Positives = 222/222 (100%), Gaps = 0/222 (0%)
Query 1 VHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
+HESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE
Sbjct 1 MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
Query 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS
Sbjct 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
Query 121 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN 180
TH+PDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN
Sbjct 121 THNPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGIN 180
Query 181 AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
Sbjct 181 AQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
>gi|289748898|ref|ZP_06508276.1| thiamine-phosphate pyrophosphorylase thiE [Mycobacterium tuberculosis
T92]
gi|289689485|gb|EFD56914.1| thiamine-phosphate pyrophosphorylase thiE [Mycobacterium tuberculosis
T92]
Length=212
Score = 414 bits (1063), Expect = 7e-114, Method: Compositional matrix adjust.
Identities = 211/212 (99%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 11 LYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADA 70
+YLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADA
Sbjct 1 MYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADA 60
Query 71 AHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAA 130
AHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAA
Sbjct 61 AHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAA 120
Query 131 AAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDA 190
AAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDA
Sbjct 121 AAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDA 180
Query 191 GARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
GARRIVVVRAITSADDPRAAAEQLRSALTAAN
Sbjct 181 GARRIVVVRAITSADDPRAAAEQLRSALTAAN 212
>gi|254818979|ref|ZP_05223980.1| thiamine-phosphate pyrophosphorylase [Mycobacterium intracellulare
ATCC 13950]
Length=223
Score = 338 bits (868), Expect = 3e-91, Method: Compositional matrix adjust.
Identities = 176/219 (81%), Positives = 194/219 (89%), Gaps = 1/219 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
S LA+ARLYLCTDARRERGDLA+FA+AALAGGVDIIQLRDKGS GE RFGPL+AR+ELAA
Sbjct 6 SVLATARLYLCTDARRERGDLAEFADAALAGGVDIIQLRDKGSAGEQRFGPLEAREELAA 65
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
CEILADAA R+GALFAVNDRADIARAAGADVLHLGQ DLP++VAR I+ PD L+G S+H
Sbjct 66 CEILADAARRHGALFAVNDRADIARAAGADVLHLGQGDLPLDVARDIVGPDVLLGLSSHS 125
Query 124 PDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
DQ AAA +ADYFCVGPCWPTPTKP RAAPGLGLVR AA L G DKPWFAIGGI+AQR
Sbjct 126 ADQAGAAAVSEADYFCVGPCWPTPTKPDRAAPGLGLVRAAAGL-GTDKPWFAIGGIDAQR 184
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
LP VLD+GARR+VVVRAIT+A DPRAAA +L SAL AA+
Sbjct 185 LPEVLDSGARRVVVVRAITAASDPRAAARRLSSALAAAS 223
>gi|289756483|ref|ZP_06515861.1| thiamin-phosphate pyrophosphorylase [Mycobacterium tuberculosis
T85]
gi|289712047|gb|EFD76059.1| thiamin-phosphate pyrophosphorylase [Mycobacterium tuberculosis
T85]
Length=204
Score = 336 bits (862), Expect = 1e-90, Method: Compositional matrix adjust.
Identities = 170/171 (99%), Positives = 171/171 (100%), Gaps = 0/171 (0%)
Query 1 VHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
+HESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE
Sbjct 1 MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDE 60
Query 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS
Sbjct 61 LAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRS 120
Query 121 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDK 171
THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDK
Sbjct 121 THDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDK 171
>gi|118465379|ref|YP_883874.1| thiamine-phosphate pyrophosphorylase [Mycobacterium avium 104]
gi|166228777|sp|A0QLT6.1|THIE_MYCA1 RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|118166666|gb|ABK67563.1| thiamine-phosphate pyrophosphorylase [Mycobacterium avium 104]
Length=223
Score = 320 bits (820), Expect = 9e-86, Method: Compositional matrix adjust.
Identities = 165/197 (84%), Positives = 179/197 (91%), Gaps = 1/197 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
LA+ARLYLCTDARRERGDLA+FA+AALAGGVD+IQLRDKGSPGE RFGPL+ARDELAACE
Sbjct 8 LAAARLYLCTDARRERGDLAEFADAALAGGVDVIQLRDKGSPGEQRFGPLEARDELAACE 67
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
ILADAA R+GALFAVNDRADIARAAGADVLHLGQ DLP++VAR + PD L+G S+HD D
Sbjct 68 ILADAARRHGALFAVNDRADIARAAGADVLHLGQGDLPLDVARAFVGPDVLLGLSSHDRD 127
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
Q+ AAAAG ADYFCVGPCWPTPTKPGRAAPGL LVR AAEL KPWFAIGGI+AQRLP
Sbjct 128 QMTAAAAGPADYFCVGPCWPTPTKPGRAAPGLALVRAAAEL-RTGKPWFAIGGIDAQRLP 186
Query 186 AVLDAGARRIVVVRAIT 202
VLDAGARR+VVVRAIT
Sbjct 187 EVLDAGARRVVVVRAIT 203
>gi|41409995|ref|NP_962831.1| thiamine-phosphate pyrophosphorylase [Mycobacterium avium subsp.
paratuberculosis K-10]
gi|47606067|sp|P61412.1|THIE_MYCPA RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|41398828|gb|AAS06447.1| ThiE [Mycobacterium avium subsp. paratuberculosis K-10]
Length=223
Score = 314 bits (804), Expect = 7e-84, Method: Compositional matrix adjust.
Identities = 166/197 (85%), Positives = 179/197 (91%), Gaps = 1/197 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
LA+ARLYLCTDARRERGDLA+FA+AALAGGVD+IQLRDKGSPGE RFGPL+ARDELAACE
Sbjct 8 LAAARLYLCTDARRERGDLAEFADAALAGGVDVIQLRDKGSPGEQRFGPLEARDELAACE 67
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
ILADAA R+GALFAVNDRADIARAAGADVLHLGQ DLP+ VAR + PD L+G S+HD D
Sbjct 68 ILADAARRHGALFAVNDRADIARAAGADVLHLGQGDLPLEVARAFVGPDVLLGLSSHDRD 127
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
Q+AAAAAG ADYFCVGPCWPTPTKPGRAAPGL LVR AAEL KPWFAIGGI+AQRLP
Sbjct 128 QMAAAAAGPADYFCVGPCWPTPTKPGRAAPGLALVRAAAEL-HTGKPWFAIGGIDAQRLP 186
Query 186 AVLDAGARRIVVVRAIT 202
VLDAGARR+VVVRAIT
Sbjct 187 EVLDAGARRVVVVRAIT 203
>gi|296167872|ref|ZP_06850055.1| thiamin-phosphate pyrophosphorylase [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896997|gb|EFG76620.1| thiamin-phosphate pyrophosphorylase [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=223
Score = 313 bits (801), Expect = 2e-83, Method: Compositional matrix adjust.
Identities = 163/199 (82%), Positives = 177/199 (89%), Gaps = 1/199 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RLA+ARLYLCTDARRERGDLA+FA+AALAGGVDIIQLRDKGS GE RFGPL+ARDELAA
Sbjct 6 TRLAAARLYLCTDARRERGDLAEFADAALAGGVDIIQLRDKGSAGERRFGPLEARDELAA 65
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
CEILADAA R+GALFAVNDRADIARAAGADVLHLGQ DLP++VAR I+ PDTL+G S+HD
Sbjct 66 CEILADAARRHGALFAVNDRADIARAAGADVLHLGQGDLPLDVARGIVGPDTLLGLSSHD 125
Query 124 PDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
DQ AA+A +ADYFCVGPCWPTPTKPGR APGL LVR AA GG KPWFAIGGI+ R
Sbjct 126 RDQAVAASASEADYFCVGPCWPTPTKPGREAPGLPLVRAAAGFGG-AKPWFAIGGIDEAR 184
Query 184 LPAVLDAGARRIVVVRAIT 202
LP VL AGARRIVVVRAIT
Sbjct 185 LPEVLAAGARRIVVVRAIT 203
>gi|336460362|gb|EGO39262.1| thiamine-phosphate pyrophosphorylase [Mycobacterium avium subsp.
paratuberculosis S397]
Length=223
Score = 311 bits (797), Expect = 5e-83, Method: Compositional matrix adjust.
Identities = 165/197 (84%), Positives = 178/197 (91%), Gaps = 1/197 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
LA+ARLYLCTDARRERGDLA+FA+AALAGGVD+IQLRDKGSPGE RF PL+ARDELAACE
Sbjct 8 LAAARLYLCTDARRERGDLAEFADAALAGGVDVIQLRDKGSPGEQRFRPLEARDELAACE 67
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
ILADAA R+GALFAVNDRADIARAAGADVLHLGQ DLP+ VAR + PD L+G S+HD D
Sbjct 68 ILADAARRHGALFAVNDRADIARAAGADVLHLGQGDLPLEVARAFVGPDVLLGLSSHDRD 127
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
Q+AAAAAG ADYFCVGPCWPTPTKPGRAAPGL LVR AAEL KPWFAIGGI+AQRLP
Sbjct 128 QMAAAAAGPADYFCVGPCWPTPTKPGRAAPGLALVRAAAEL-HTGKPWFAIGGIDAQRLP 186
Query 186 AVLDAGARRIVVVRAIT 202
VLDAGARR+VVVRAIT
Sbjct 187 EVLDAGARRVVVVRAIT 203
>gi|342859106|ref|ZP_08715760.1| thiamine-phosphate pyrophosphorylase [Mycobacterium colombiense
CECT 3035]
gi|342133347|gb|EGT86550.1| thiamine-phosphate pyrophosphorylase [Mycobacterium colombiense
CECT 3035]
Length=211
Score = 308 bits (789), Expect = 4e-82, Method: Compositional matrix adjust.
Identities = 168/212 (80%), Positives = 185/212 (88%), Gaps = 1/212 (0%)
Query 11 LYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADA 70
+YLCTDARRERGDLA+FA+AALAGGVDIIQLRDKGS GE RFGPL+AR+ELAAC+ILA A
Sbjct 1 MYLCTDARRERGDLAEFADAALAGGVDIIQLRDKGSAGEQRFGPLEAREELAACQILAGA 60
Query 71 AHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAA 130
A R+GALFAVNDRADIARAAGADVLHLGQ DLP +AR I PD L+G S+HD +Q AAA
Sbjct 61 ARRHGALFAVNDRADIARAAGADVLHLGQGDLPPAIARDIAGPDVLLGLSSHDREQAAAA 120
Query 131 AAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDA 190
A G+ DYFCVGPCWPTPTKPGRAAPGLGLVR AAE DKPWFAIGGI+ +RLP VLDA
Sbjct 121 ARGEVDYFCVGPCWPTPTKPGRAAPGLGLVRAAAEFNA-DKPWFAIGGIDERRLPEVLDA 179
Query 191 GARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
GARRIVVVRAIT+A DPRAAA +L SAL AA+
Sbjct 180 GARRIVVVRAITAAADPRAAARRLSSALAAAS 211
>gi|254777186|ref|ZP_05218702.1| thiamine-phosphate pyrophosphorylase [Mycobacterium avium subsp.
avium ATCC 25291]
Length=223
Score = 303 bits (776), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 165/197 (84%), Positives = 177/197 (90%), Gaps = 1/197 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
LA+ARLYLCTDARRERGDLA+FA AALAGGVD+IQLRDKGSPGE RFGPL+ARDELAACE
Sbjct 8 LAAARLYLCTDARRERGDLAEFAAAALAGGVDVIQLRDKGSPGEQRFGPLEARDELAACE 67
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
ILADAA R+GALFAVNDRADIARAAGADVLHLGQ DLP+ VAR + PD L+G S+HD D
Sbjct 68 ILADAARRHGALFAVNDRADIARAAGADVLHLGQGDLPLEVARAFVGPDVLLGLSSHDRD 127
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
Q+ AAAAG ADYFCVGPCWPTPTKPGRAAPGL LVR AAEL KPWFAIGGI+AQRLP
Sbjct 128 QMTAAAAGPADYFCVGPCWPTPTKPGRAAPGLALVRAAAEL-RTGKPWFAIGGIDAQRLP 186
Query 186 AVLDAGARRIVVVRAIT 202
VLDAGARR+VVVRAIT
Sbjct 187 EVLDAGARRVVVVRAIT 203
>gi|15827073|ref|NP_301336.1| thiamine-phosphate pyrophosphorylase [Mycobacterium leprae TN]
gi|221229551|ref|YP_002502967.1| thiamine-phosphate pyrophosphorylase [Mycobacterium leprae Br4923]
gi|7388315|sp|Q9ZBL5.1|THIE_MYCLE RecName: Full=Probable thiamine-phosphate pyrophosphorylase;
Short=TMP pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|254784185|sp|B8ZU95.1|THIE_MYCLB RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|4154053|emb|CAA22707.1| probable thiamine-phosphate pyrophosphorylase [Mycobacterium
leprae]
gi|13092621|emb|CAC29808.1| putative thiamine-phosphate pyrophosphorylase [Mycobacterium
leprae]
gi|219932658|emb|CAR70393.1| putative thiamine-phosphate pyrophosphorylase [Mycobacterium
leprae Br4923]
Length=235
Score = 299 bits (765), Expect = 2e-79, Method: Compositional matrix adjust.
Identities = 174/224 (78%), Positives = 183/224 (82%), Gaps = 5/224 (2%)
Query 3 ESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELA 62
+RLA ARLYLCTDARRERGDLAQF AALAGGVDI+QLRDKGS GE +FGPL+ARD LA
Sbjct 13 STRLAKARLYLCTDARRERGDLAQFVNAALAGGVDIVQLRDKGSVGEQQFGPLEARDALA 72
Query 63 ACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTH 122
ACEI DA R+ ALFAVNDRADIARAAGADVLHLGQ DLP VARQI+ LIG STH
Sbjct 73 ACEIFTDATGRHDALFAVNDRADIARAAGADVLHLGQGDLPPGVARQIVCRQMLIGLSTH 132
Query 123 DPDQVAAAA----AGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGG 178
D QVAAA AG DYFCVGPCWPTPTKP R APGL LVR AAEL G DKPWFAIGG
Sbjct 133 DRHQVAAAVAALDAGLVDYFCVGPCWPTPTKPDRPAPGLELVRAAAELAG-DKPWFAIGG 191
Query 179 INAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
I+AQRLP VL AGARRIVVVRAIT+A DPRAAAEQL S LTA +
Sbjct 192 IDAQRLPDVLHAGARRIVVVRAITAAADPRAAAEQLISTLTATS 235
>gi|118467945|ref|YP_885195.1| thiamine-phosphate pyrophosphorylase [Mycobacterium smegmatis
str. MC2 155]
gi|189030573|sp|A0QQK7.1|THIE_MYCS2 RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|118169232|gb|ABK70128.1| thiamine-phosphate pyrophosphorylase [Mycobacterium smegmatis
str. MC2 155]
Length=227
Score = 298 bits (763), Expect = 4e-79, Method: Compositional matrix adjust.
Identities = 158/219 (73%), Positives = 178/219 (82%), Gaps = 1/219 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RL A LYLCTDARRERGDLA+FA+AALAGGVD+IQLRDKGS GE +FGPL+AR EL A
Sbjct 10 QRLQRASLYLCTDARRERGDLAEFADAALAGGVDLIQLRDKGSAGEKQFGPLEARQELEA 69
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
EILADAA R+GAL AVNDRADIA AAGADVLHLGQ DLP++VAR I+ +IGRSTHD
Sbjct 70 LEILADAARRHGALLAVNDRADIALAAGADVLHLGQDDLPLDVARGIIGRRPVIGRSTHD 129
Query 124 PDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
Q+A A DYFCVGPCWPTPTKPGR APGL LVR A KPWFAIGGI+ +R
Sbjct 130 AAQMAVAIEERVDYFCVGPCWPTPTKPGRPAPGLDLVRATAA-HSPGKPWFAIGGIDQER 188
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
LP VL AGARR+VVVRAIT+ADDP+AAAE L++A++AA
Sbjct 189 LPEVLAAGARRVVVVRAITAADDPKAAAEDLKAAISAAG 227
>gi|126433146|ref|YP_001068837.1| thiamine-phosphate pyrophosphorylase [Mycobacterium sp. JLS]
gi|189030574|sp|A3PTW9.1|THIE_MYCSJ RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|126232946|gb|ABN96346.1| thiamine-phosphate diphosphorylase [Mycobacterium sp. JLS]
Length=226
Score = 290 bits (742), Expect = 1e-76, Method: Compositional matrix adjust.
Identities = 164/215 (77%), Positives = 182/215 (85%), Gaps = 1/215 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
LA A LYLCTDARRERGDLA+FA+AALAGGVD+IQLRDKGS GE RFGPL+AR+ELAA E
Sbjct 12 LAQASLYLCTDARRERGDLAEFADAALAGGVDLIQLRDKGSAGERRFGPLEAREELAALE 71
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
ILA+AA R GAL AVNDRADIA AAGADVLHLGQ DLP+ VAR+I+ P LIGRSTHD
Sbjct 72 ILAEAARRRGALLAVNDRADIALAAGADVLHLGQDDLPLPVARRIIGPRPLIGRSTHDSA 131
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
QV+AA A + DYFCVGPCWPTPTKPGR APGLGLVR A +KPWFAIGGI+ RLP
Sbjct 132 QVSAAVAEEVDYFCVGPCWPTPTKPGREAPGLGLVREVASR-ATEKPWFAIGGIDEARLP 190
Query 186 AVLDAGARRIVVVRAITSADDPRAAAEQLRSALTA 220
VLDAGARRIVVVRAIT+ADDP+AAA +L+ AL +
Sbjct 191 EVLDAGARRIVVVRAITAADDPKAAARRLKDALVS 225
>gi|240168880|ref|ZP_04747539.1| thiamine-phosphate pyrophosphorylase [Mycobacterium kansasii
ATCC 12478]
Length=209
Score = 287 bits (735), Expect = 6e-76, Method: Compositional matrix adjust.
Identities = 170/210 (81%), Positives = 186/210 (89%), Gaps = 1/210 (0%)
Query 13 LCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAH 72
+CTDARRERGDLA+FA+AALAGGVDIIQLRDKGS E R GPL+A DELAACEIL DAA
Sbjct 1 MCTDARRERGDLAEFADAALAGGVDIIQLRDKGSAAEQRLGPLEALDELAACEILVDAAR 60
Query 73 RYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAA 132
R+GALFAVNDRADIA AAGADVLHLGQRDLP ++AR+I+ P LIGRSTHD DQVAAAA
Sbjct 61 RHGALFAVNDRADIAAAAGADVLHLGQRDLPSSIAREIVGPGVLIGRSTHDRDQVAAAAV 120
Query 133 GDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDAGA 192
GDADYFC GPCWPTPTKPGR APGL LVR AA +GG DKPWFAIGGI+A RLP V+ AGA
Sbjct 121 GDADYFCAGPCWPTPTKPGRPAPGLDLVRAAAAIGG-DKPWFAIGGIDAPRLPEVIAAGA 179
Query 193 RRIVVVRAITSADDPRAAAEQLRSALTAAN 222
RRIVVVRAIT+ADDP+AAA+QLRSAL AA+
Sbjct 180 RRIVVVRAITAADDPKAAAQQLRSALPAAS 209
>gi|145220803|ref|YP_001131481.1| thiamine-phosphate pyrophosphorylase [Mycobacterium gilvum PYR-GCK]
gi|189030572|sp|A4T2R5.1|THIE_MYCGI RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|145213289|gb|ABP42693.1| thiamine-phosphate diphosphorylase [Mycobacterium gilvum PYR-GCK]
Length=237
Score = 287 bits (735), Expect = 7e-76, Method: Compositional matrix adjust.
Identities = 163/216 (76%), Positives = 179/216 (83%), Gaps = 2/216 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
L ARLYLCTDARRERGDLA FA+AALAGGVDIIQLRDKGSPGE FGPL+AR E+ A
Sbjct 23 LQGARLYLCTDARRERGDLADFADAALAGGVDIIQLRDKGSPGEKAFGPLEARAEIDALH 82
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
+LA+AA R+ AL AVNDRADIARA+GA+VLHLGQ DLP+ VARQI+ D +IGRSTHD
Sbjct 83 VLAEAARRHNALVAVNDRADIARASGAEVLHLGQDDLPLTVARQIVG-DRVIGRSTHDLA 141
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
Q AA A D DYFCVGPCWPTPTKPGRAAPGL LVR A L KPWFAIGGI+AQRLP
Sbjct 142 QAEAAIAEDVDYFCVGPCWPTPTKPGRAAPGLDLVREVAAL-NTTKPWFAIGGIDAQRLP 200
Query 186 AVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
VLDAGARR+VVVRAIT+A+DPRAAAEQL L +A
Sbjct 201 DVLDAGARRVVVVRAITAAEDPRAAAEQLAGMLDSA 236
>gi|120401722|ref|YP_951551.1| thiamine-phosphate pyrophosphorylase [Mycobacterium vanbaalenii
PYR-1]
gi|189030577|sp|A1T2Z5.1|THIE_MYCVP RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|119954540|gb|ABM11545.1| thiamine-phosphate diphosphorylase [Mycobacterium vanbaalenii
PYR-1]
Length=221
Score = 286 bits (733), Expect = 1e-75, Method: Compositional matrix adjust.
Identities = 164/223 (74%), Positives = 185/223 (83%), Gaps = 3/223 (1%)
Query 1 VHESR-LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARD 59
+ ESR L SA LYLCTDARRERGDLA+FA+AALAGGVDIIQLRDKGS GE RFGPL+AR+
Sbjct 1 MRESRKLDSAALYLCTDARRERGDLAEFADAALAGGVDIIQLRDKGSAGEQRFGPLEARE 60
Query 60 ELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGR 119
E+ LADAA R+GALFAVNDRADIA AA ADVLHLGQ DLP+ VAR+I+ D ++GR
Sbjct 61 EIEVLATLADAARRHGALFAVNDRADIALAADADVLHLGQDDLPLTVARRIVG-DRIVGR 119
Query 120 STHDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGI 179
STHD DQV AA D +YFCVGPCWPTPTKPGR APGL L+R A L G DKPWFAIGGI
Sbjct 120 STHDLDQVRAAVGEDVNYFCVGPCWPTPTKPGRPAPGLDLIRATAAL-GTDKPWFAIGGI 178
Query 180 NAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
+A+RLP VLDAGARR+VVVRAIT+ADDP AAA++L L+AA
Sbjct 179 DAERLPEVLDAGARRVVVVRAITAADDPGAAAQRLAGMLSAAG 221
>gi|108797524|ref|YP_637721.1| thiamine-phosphate pyrophosphorylase [Mycobacterium sp. MCS]
gi|119866610|ref|YP_936562.1| thiamine-phosphate pyrophosphorylase [Mycobacterium sp. KMS]
gi|123179600|sp|Q1BEL9.1|THIE_MYCSS RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|189030575|sp|A1UAB4.1|THIE_MYCSK RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|108767943|gb|ABG06665.1| thiamine-phosphate diphosphorylase [Mycobacterium sp. MCS]
gi|119692699|gb|ABL89772.1| thiamine-phosphate diphosphorylase [Mycobacterium sp. KMS]
Length=226
Score = 281 bits (719), Expect = 4e-74, Method: Compositional matrix adjust.
Identities = 165/215 (77%), Positives = 183/215 (86%), Gaps = 1/215 (0%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
LA A LYLCTDARRERGDLA+FA+AALAGGVD+IQLRDKGS GE RFGPL+AR+ELAA E
Sbjct 12 LAQASLYLCTDARRERGDLAEFADAALAGGVDLIQLRDKGSAGERRFGPLEAREELAALE 71
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
ILA+AA R+GAL AVNDRADIA AAGADVLHLGQ DLP+ VAR+I+ P LIGRSTHD
Sbjct 72 ILAEAARRHGALLAVNDRADIALAAGADVLHLGQDDLPLPVARRIIGPSPLIGRSTHDSA 131
Query 126 QVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLP 185
QVAAA A + DYFCVGPCWPTPTKPGR APGLGLVR A +KPWFAIGGI+ RLP
Sbjct 132 QVAAAVAEEVDYFCVGPCWPTPTKPGREAPGLGLVREVASR-ATEKPWFAIGGIDEARLP 190
Query 186 AVLDAGARRIVVVRAITSADDPRAAAEQLRSALTA 220
VLDAGARRIVVVRAIT+ADDP+AAA +L+ AL +
Sbjct 191 EVLDAGARRIVVVRAITAADDPKAAARRLKDALVS 225
>gi|333989025|ref|YP_004521639.1| thiamine-phosphate pyrophosphorylase ThiE [Mycobacterium sp.
JDM601]
gi|333484993|gb|AEF34385.1| thiamine-phosphate pyrophosphorylase ThiE [Mycobacterium sp.
JDM601]
Length=225
Score = 280 bits (717), Expect = 8e-74, Method: Compositional matrix adjust.
Identities = 161/218 (74%), Positives = 182/218 (84%), Gaps = 1/218 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RL ARLYLCTDARRE+GDLA+FAEAALAGGVD+IQLRDKGSPGE +FGPL+ARDELAA
Sbjct 9 TRLVDARLYLCTDARREKGDLAEFAEAALAGGVDVIQLRDKGSPGEQQFGPLEARDELAA 68
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
EIL+ AA R+GAL AVNDRADIARAA DVLHLGQ DLP+ +AR+I+ PD LIGRSTHD
Sbjct 69 LEILSAAARRHGALLAVNDRADIARAAEVDVLHLGQDDLPLPIAREIVGPDVLIGRSTHD 128
Query 124 PDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
QV AA DYFCVGPCWPTPTKPGR APGL L+R A + DKPWFAIGGI+A+R
Sbjct 129 GQQVRAALTEPVDYFCVGPCWPTPTKPGRPAPGLELLRFAVDQRA-DKPWFAIGGIDAER 187
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
LP V+ AGA R+VVVRAIT+ADDP+AAA L +ALT A
Sbjct 188 LPQVVAAGAGRVVVVRAITAADDPQAAASALLAALTGA 225
>gi|315442244|ref|YP_004075123.1| thiamine-phosphate diphosphorylase [Mycobacterium sp. Spyr1]
gi|315260547|gb|ADT97288.1| thiamine-phosphate diphosphorylase [Mycobacterium sp. Spyr1]
Length=224
Score = 278 bits (710), Expect = 6e-73, Method: Compositional matrix adjust.
Identities = 164/219 (75%), Positives = 180/219 (83%), Gaps = 5/219 (2%)
Query 6 LASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACE 65
L ARLYLCTDARRERGDLA FA+AALAGGVDIIQLRDKGSPGE FGPL+AR E+ A
Sbjct 7 LQGARLYLCTDARRERGDLADFADAALAGGVDIIQLRDKGSPGEKAFGPLEARAEIDALH 66
Query 66 ILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPD 125
+LA+AA R+ AL AVNDRADIARA+GADVLHLGQ DLP+ VARQI+ D ++GRSTHD
Sbjct 67 VLAEAARRHNALVAVNDRADIARASGADVLHLGQDDLPLTVARQIVG-DRVVGRSTHDLA 125
Query 126 QVAAAAAG--DA-DYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
Q AA A DA DYFCVGPCWPTPTKPGRAAPGL LVR A L KPWFAIGGI+AQ
Sbjct 126 QAEAAIADGPDAPDYFCVGPCWPTPTKPGRAAPGLDLVREVAAL-NTAKPWFAIGGIDAQ 184
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
RLP VLDAGARR+VVVRAIT+A+DPRAAAEQL L +A
Sbjct 185 RLPDVLDAGARRVVVVRAITAAEDPRAAAEQLAGMLDSA 223
>gi|183980740|ref|YP_001849031.1| thiamine-phosphate pyrophosphorylase ThiE [Mycobacterium marinum
M]
gi|238690949|sp|B2HPZ9.1|THIE_MYCMM RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|183174066|gb|ACC39176.1| thiamine-phosphate pyrophosphorylase ThiE [Mycobacterium marinum
M]
Length=220
Score = 275 bits (703), Expect = 4e-72, Method: Compositional matrix adjust.
Identities = 176/219 (81%), Positives = 190/219 (87%), Gaps = 1/219 (0%)
Query 3 ESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELA 62
SRLA+ARLYLCTDARRERGDLA FA+AALAGGVDIIQLRDKGS GE RFGPL+ARDELA
Sbjct 2 HSRLATARLYLCTDARRERGDLADFADAALAGGVDIIQLRDKGSAGEQRFGPLEARDELA 61
Query 63 ACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTH 122
ACEILADAA R+ A+FAVNDRADIARAA ADVLHLGQRDLPV+VAR I P TLIG+STH
Sbjct 62 ACEILADAAARHAAMFAVNDRADIARAARADVLHLGQRDLPVDVARAITGPATLIGQSTH 121
Query 123 DPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
D DQV+AAA G DYFCVGPCWPTPTKPGR APGL LVR AA++ G KPWFAIGGI+
Sbjct 122 DRDQVSAAAIGAVDYFCVGPCWPTPTKPGRTAPGLDLVRFAADVAG-AKPWFAIGGIDGV 180
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
RLP VL AGARRIVVVRAIT+ADDPR AA +L+S L AA
Sbjct 181 RLPEVLAAGARRIVVVRAITAADDPREAAAKLKSELLAA 219
>gi|118618240|ref|YP_906572.1| thiamine-phosphate pyrophosphorylase [Mycobacterium ulcerans
Agy99]
gi|189030576|sp|A0PRY2.1|THIE_MYCUA RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|118570350|gb|ABL05101.1| thiamine-phosphate pyrophosphorylase ThiE [Mycobacterium ulcerans
Agy99]
Length=220
Score = 275 bits (703), Expect = 4e-72, Method: Compositional matrix adjust.
Identities = 176/219 (81%), Positives = 190/219 (87%), Gaps = 1/219 (0%)
Query 3 ESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELA 62
SRLA+ARLYLCTDARRERGDLA FA+AALAGGVDIIQLRDKGS GE RFGPL+ARDELA
Sbjct 2 HSRLATARLYLCTDARRERGDLADFADAALAGGVDIIQLRDKGSAGEQRFGPLEARDELA 61
Query 63 ACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTH 122
ACEILADAA R+ A+FAVNDRADIARAA ADVLHLGQRDLPV+VAR I P TLIG+STH
Sbjct 62 ACEILADAAARHAAMFAVNDRADIARAARADVLHLGQRDLPVDVARAITGPATLIGQSTH 121
Query 123 DPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
D DQV+AAA G DYFCVGPCWPTPTKPGR APGL LVR AA++ G KPWFAIGGI+
Sbjct 122 DRDQVSAAAIGAVDYFCVGPCWPTPTKPGRTAPGLDLVRFAADVAG-AKPWFAIGGIDGL 180
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
RLP VL AGARRIVVVRAIT+ADDPR AA +L+S L AA
Sbjct 181 RLPEVLAAGARRIVVVRAITAADDPREAAAKLKSELLAA 219
>gi|312141234|ref|YP_004008570.1| thiamine phosphate pyrophosphorylase, thie [Rhodococcus equi
103S]
gi|325673936|ref|ZP_08153626.1| thiamin-phosphate pyrophosphorylase [Rhodococcus equi ATCC 33707]
gi|311890573|emb|CBH49891.1| thiamine phosphate pyrophosphorylase, ThiE [Rhodococcus equi
103S]
gi|325555201|gb|EGD24873.1| thiamin-phosphate pyrophosphorylase [Rhodococcus equi ATCC 33707]
Length=230
Score = 271 bits (692), Expect = 7e-71, Method: Compositional matrix adjust.
Identities = 144/216 (67%), Positives = 171/216 (80%), Gaps = 2/216 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RLA ARLYLCTDARR++GDLAQF +AALAGGVDI+QLRDKGS GE FGP++ ++ELAA
Sbjct 14 ERLADARLYLCTDARRDKGDLAQFVDAALAGGVDIVQLRDKGSAGEREFGPMEVKEELAA 73
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
++ AA R+GAL AVNDRAD+A AAGADVLHLGQ DLPV+ ARQI+ PD +IGRST++
Sbjct 74 LAVIGAAARRHGALLAVNDRADVALAAGADVLHLGQNDLPVHYARQIVGPDVVIGRSTNN 133
Query 124 PDQVA-AAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
Q + AA D DYFC GP W TPTKPGRAA G+ LVR AE +PWFAIGG++ +
Sbjct 134 RAQASLAAIEEDVDYFCTGPVWATPTKPGRAASGIELVRSTAE-AQPSRPWFAIGGVDHE 192
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSAL 218
RLP +L+AGA RIVVVRAIT+ADDP+AAA L AL
Sbjct 193 RLPEILEAGATRIVVVRAITAADDPKAAARALSDAL 228
>gi|54027314|ref|YP_121556.1| thiamine-phosphate pyrophosphorylase [Nocardia farcinica IFM
10152]
gi|81822823|sp|Q5YNP9.1|THIE_NOCFA RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|54018822|dbj|BAD60192.1| putative thiamine monophosphate synthase [Nocardia farcinica
IFM 10152]
Length=232
Score = 268 bits (686), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 148/219 (68%), Positives = 167/219 (77%), Gaps = 2/219 (0%)
Query 5 RLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAAC 64
RLA+ARLYLCTDARRE+GDLA+FAEAA AGGVDIIQLRDKGSPGE +FGPL+A+ EL A
Sbjct 15 RLATARLYLCTDARREKGDLAKFAEAAFAGGVDIIQLRDKGSPGEAKFGPLEAKAELGAL 74
Query 65 EILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDP 124
L A R+G L AVNDRADIA AAGADVLHLGQ DLP AR+I+ PD +IGRSTH+
Sbjct 75 AELKAVARRHGGLVAVNDRADIALAAGADVLHLGQGDLPPWYARRIVGPDVVIGRSTHNR 134
Query 125 DQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
Q AA + DYFC GP W TPTKPGR A GL LVR A+ +PWFAIGGI+ +R
Sbjct 135 AQAGLAAIDEHIDYFCTGPVWSTPTKPGRQAAGLDLVRSTAD-SHPTRPWFAIGGIDLER 193
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
LP +L AGA RIVVVRAIT A DP AAA L+SAL AA+
Sbjct 194 LPELLAAGADRIVVVRAITEARDPEAAARALKSALLAAS 232
>gi|302530628|ref|ZP_07282970.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. AA4]
gi|302439523|gb|EFL11339.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. AA4]
Length=221
Score = 267 bits (682), Expect = 1e-69, Method: Compositional matrix adjust.
Identities = 140/216 (65%), Positives = 166/216 (77%), Gaps = 7/216 (3%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RLA ARLYLCTDAR RGDLA+FA+AALAGGVDI+QLRDK PL+A+ E+AA
Sbjct 11 TRLADARLYLCTDARTSRGDLAEFADAALAGGVDIVQLRDKTGGA-----PLEAKQEIAA 65
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E+LA+A R+GAL +VNDRAD+A A GADVLHLGQ D+PV++AR++L D +IGRSTH
Sbjct 66 LEVLAEACARHGALLSVNDRADVALAVGADVLHLGQDDIPVSLARRVLGDDVVIGRSTHS 125
Query 124 PDQ-VAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
Q AAA +YFC GPCWPTPTKPGR APGL LVR A G D+PWFAIGGI+
Sbjct 126 EQQATAAATETGVNYFCTGPCWPTPTKPGRYAPGLDLVRATAA-SGTDRPWFAIGGIDET 184
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSAL 218
RLP VL AGA RIVVVRAIT A+DP+AAA+ L++ L
Sbjct 185 RLPEVLAAGATRIVVVRAITEAEDPKAAAQTLKAQL 220
>gi|333918210|ref|YP_004491791.1| Thiamine-phosphate pyrophosphorylase [Amycolicicoccus subflavus
DQS3-9A1]
gi|333480431|gb|AEF38991.1| Thiamine-phosphate pyrophosphorylase [Amycolicicoccus subflavus
DQS3-9A1]
Length=222
Score = 265 bits (677), Expect = 4e-69, Method: Compositional matrix adjust.
Identities = 144/217 (67%), Positives = 175/217 (81%), Gaps = 2/217 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RL +A+LYLCTDARR++ DLA+FAEAAL+GGVDIIQLRDKGSPGE ++GPL+A+ E+AA
Sbjct 6 ERLRTAQLYLCTDARRDKDDLAEFAEAALSGGVDIIQLRDKGSPGEKQYGPLEAQHEIAA 65
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
IL AA R+GAL AVNDRADIA AAGAD+LHLGQ DLPV+ AR+IL LIGRSTH+
Sbjct 66 LAILGAAAKRHGALLAVNDRADIALAAGADILHLGQDDLPVHYARKILGERPLIGRSTHN 125
Query 124 PDQVAAAAAGDA-DYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+Q AA + DYFCVGPCW TPTKPGR+A GLGLVR A+ +PWFAIGGI+ +
Sbjct 126 AEQARDAAIEEGVDYFCVGPCWTTPTKPGRSAAGLGLVRSTAD-HAPARPWFAIGGIDEE 184
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALT 219
RLP + +GA+RIVVVRAIT A DP AAA+++++ALT
Sbjct 185 RLPEAVASGAQRIVVVRAITEATDPHAAAQRIKAALT 221
>gi|229493086|ref|ZP_04386881.1| thiamine-phosphate pyrophosphorylase [Rhodococcus erythropolis
SK121]
gi|229320116|gb|EEN85942.1| thiamine-phosphate pyrophosphorylase [Rhodococcus erythropolis
SK121]
Length=231
Score = 263 bits (673), Expect = 9e-69, Method: Compositional matrix adjust.
Identities = 138/206 (67%), Positives = 160/206 (78%), Gaps = 2/206 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RLA+ARLYLCTDARRE+GDLAQFAEAAL+GGVDIIQLRDKGS GE FGPL+A+DEL A
Sbjct 14 ERLAAARLYLCTDARREKGDLAQFAEAALSGGVDIIQLRDKGSAGEREFGPLEAKDELVA 73
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
ILA AA R+GAL AVNDRAD+A A+GAD+LHLGQ D+PV AR ++ D +IGRST
Sbjct 74 LGILATAARRHGALLAVNDRADLAMASGADILHLGQNDIPVPYARTVVGEDVVIGRSTSS 133
Query 124 PDQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
Q + AA + DYFC GP W TPTKP R+A GL LVR A+ +PWFAIGGI+ +
Sbjct 134 RAQASLAAIEEGVDYFCTGPVWATPTKPNRSASGLELVRSTAD-AAPPRPWFAIGGIDEE 192
Query 183 RLPAVLDAGARRIVVVRAITSADDPR 208
RLP +LDAGA RIVVVRAIT A DP+
Sbjct 193 RLPELLDAGATRIVVVRAITQASDPQ 218
>gi|169631297|ref|YP_001704946.1| thiamine-phosphate pyrophosphorylase [Mycobacterium abscessus
ATCC 19977]
gi|169243264|emb|CAM64292.1| Thiamine-phosphate pyrophosphorylase ThiE [Mycobacterium abscessus]
Length=223
Score = 263 bits (673), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 151/215 (71%), Positives = 171/215 (80%), Gaps = 2/215 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RL SA LYLCTDARRERGD A+F +AALAGGVDI+QLRDKGS GE +FG L+ +EL
Sbjct 6 ARLQSAHLYLCTDARRERGDFAEFVDAALAGGVDIVQLRDKGSAGERQFGRLEPAEELEY 65
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTH- 122
IL++AA R+GALFAVNDRADIARAAGADVLHLGQ DLP+ VAR+I+ PD LIGRSTH
Sbjct 66 LAILSEAAARHGALFAVNDRADIARAAGADVLHLGQDDLPLAVAREIVGPDVLIGRSTHD 125
Query 123 DPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
AAA + DYFC GPCWPTPTKPGR A GLGLVR AAEL KPWFAIGGI+
Sbjct 126 AEQAAAAARDDEIDYFCCGPCWPTPTKPGRTASGLGLVRTAAEL-DTSKPWFAIGGIDEA 184
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSA 217
R+P V++AGA RIVVVRAIT+A DPRAAA LR +
Sbjct 185 RVPQVVEAGASRIVVVRAITAAADPRAAAASLRGS 219
>gi|226304968|ref|YP_002764926.1| thiamine-phosphate pyrophosphorylase [Rhodococcus erythropolis
PR4]
gi|226184083|dbj|BAH32187.1| thiamine-phosphate pyrophosphorylase [Rhodococcus erythropolis
PR4]
Length=231
Score = 263 bits (671), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 138/206 (67%), Positives = 160/206 (78%), Gaps = 2/206 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RLA+ARLYLCTDARRE+GDLAQFAEAAL+GGVDIIQLRDKGS GE FGPL+A+DEL A
Sbjct 14 ERLAAARLYLCTDARREKGDLAQFAEAALSGGVDIIQLRDKGSAGEREFGPLEAKDELVA 73
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
ILA AA R+GAL AVNDRAD+A A+GAD+LHLGQ D+PV AR ++ D +IGRST
Sbjct 74 LGILAAAARRHGALLAVNDRADLAMASGADILHLGQNDIPVPYARTVVGEDVVIGRSTSS 133
Query 124 PDQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
Q + AA + DYFC GP W TPTKP R+A GL LVR A+ +PWFAIGGI+ +
Sbjct 134 RAQASLAAIEEGVDYFCTGPVWATPTKPNRSASGLELVRSTAD-AAPPRPWFAIGGIDEE 192
Query 183 RLPAVLDAGARRIVVVRAITSADDPR 208
RLP +LDAGA RIVVVRAIT A DP+
Sbjct 193 RLPELLDAGATRIVVVRAITQASDPQ 218
>gi|111019184|ref|YP_702156.1| thiamine-phosphate pyrophosphorylase [Rhodococcus jostii RHA1]
gi|110818714|gb|ABG93998.1| thiamine-phosphate diphosphorylase [Rhodococcus jostii RHA1]
Length=244
Score = 259 bits (663), Expect = 1e-67, Method: Compositional matrix adjust.
Identities = 148/219 (68%), Positives = 167/219 (77%), Gaps = 3/219 (1%)
Query 5 RLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAAC 64
RL +ARLYLCTDARRE+GDLAQFAEAAL+GGVDIIQLRDKGS GE +FG + ARDELAA
Sbjct 27 RLGTARLYLCTDARREKGDLAQFAEAALSGGVDIIQLRDKGSAGEKKFGTMDARDELAAL 86
Query 65 EILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDP 124
+LA AA R+GAL AVNDRAD+A AAGADVLHLGQ DLPV AR ++ D LIGRSTH
Sbjct 87 SVLAAAARRHGALLAVNDRADMALAAGADVLHLGQGDLPVPYARTVVGSDVLIGRSTHSR 146
Query 125 DQVAAAAAGDA-DYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
Q + AA D DYFC GP W TPTKPGR A G+ LVR A+ ++PWFAIGGI+ R
Sbjct 147 AQASLAAIEDGVDYFCTGPVWATPTKPGRTASGIDLVRSTAD-SEPNRPWFAIGGIDESR 205
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
+P +L AGA RIVVVRAIT A DP+AAA L SAL N
Sbjct 206 VPEILAAGASRIVVVRAITEARDPQAAARSL-SALLQQN 243
>gi|226361320|ref|YP_002779098.1| thiamine-phosphate pyrophosphorylase [Rhodococcus opacus B4]
gi|226239805|dbj|BAH50153.1| thiamine-phosphate pyrophosphorylase [Rhodococcus opacus B4]
Length=232
Score = 258 bits (659), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 147/219 (68%), Positives = 167/219 (77%), Gaps = 3/219 (1%)
Query 5 RLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAAC 64
RL +ARLYLCTDARRE+GDLAQFAEAAL+GGVDIIQLRDKGS GE +FG + ARDELAA
Sbjct 15 RLGTARLYLCTDARREKGDLAQFAEAALSGGVDIIQLRDKGSAGEKKFGTMDARDELAAL 74
Query 65 EILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDP 124
+LA AA R+GAL AVNDRAD+A AAGADVLHLGQ DLPV AR ++ + LIGRSTH
Sbjct 75 SVLAAAARRHGALLAVNDRADMALAAGADVLHLGQGDLPVPYARTVVGSEVLIGRSTHSR 134
Query 125 DQVAAAAAGDA-DYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
Q + AA D DYFC GP W TPTKPGR A G+ LVR A+ ++PWFAIGGI+ R
Sbjct 135 AQASLAAIEDGVDYFCTGPVWETPTKPGRTASGIDLVRSTAD-SEPNRPWFAIGGIDESR 193
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
+P +L AGA RIVVVRAIT A DP+AAA L SAL N
Sbjct 194 VPEILAAGADRIVVVRAITEARDPQAAARSL-SALLQKN 231
>gi|294628869|ref|ZP_06707429.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. e14]
gi|292832202|gb|EFF90551.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. e14]
Length=220
Score = 254 bits (648), Expect = 8e-66, Method: Compositional matrix adjust.
Identities = 140/216 (65%), Positives = 158/216 (74%), Gaps = 11/216 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RLA ARLYLCTDAR++RGDLA+F +A LAGGVDI+QLRDKG ++A +EL
Sbjct 11 ERLADARLYLCTDARKDRGDLAEFLDAVLAGGVDIVQLRDKG---------MEAGEELEH 61
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTH- 122
E+ ADA R+G L AVNDRAD+A AA ADVLHLGQ DLPV AR IL D LIGRSTH
Sbjct 62 LEVFADACARHGKLLAVNDRADVAHAARADVLHLGQGDLPVPAARAILGDDVLIGRSTHA 121
Query 123 DPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+P+ AAA DYFC GPCWPTPTKPGR APGLGLVR A LG D+PWFAIGGI+
Sbjct 122 EPEADAAAVQDGVDYFCTGPCWPTPTKPGRHAPGLGLVRHTAALGA-DRPWFAIGGIDLG 180
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSAL 218
L VL+AGARR+VVVRAIT ADDP AAA + L
Sbjct 181 NLDQVLEAGARRVVVVRAITEADDPGAAAAEFAERL 216
>gi|324998504|ref|ZP_08119616.1| thiamine-phosphate pyrophosphorylase [Pseudonocardia sp. P1]
Length=227
Score = 253 bits (646), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 139/203 (69%), Positives = 159/203 (79%), Gaps = 10/203 (4%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RL ARLYLCTDAR ERGDLA+FA+AALAGGVD++QLRDKG GPL+AR ELAA
Sbjct 15 ARLQDARLYLCTDARTERGDLAEFADAALAGGVDVVQLRDKGGDD----GPLEARAELAA 70
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E+LADA R+GAL AVNDRAD+A AAGADVLHLGQ DLPV+ AR+++ D L+GRS+H
Sbjct 71 LEVLADACRRHGALLAVNDRADVALAAGADVLHLGQDDLPVHWARRVVGDDVLVGRSSHS 130
Query 124 PDQVAAAAAGDA-DYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGD--DKPWFAIGGIN 180
D+ AAA D DYFC GPCWPTPTKPGR APGL LVR E+ G +PWFAIGGI+
Sbjct 131 ADETLAAAGEDGVDYFCAGPCWPTPTKPGRPAPGLDLVR---EVAGRAPARPWFAIGGID 187
Query 181 AQRLPAVLDAGARRIVVVRAITS 203
+RL AVLDAGA RIVVVRAIT
Sbjct 188 EERLDAVLDAGADRIVVVRAITQ 210
>gi|257057424|ref|YP_003135256.1| thiamine-phosphate pyrophosphorylase [Saccharomonospora viridis
DSM 43017]
gi|256587296|gb|ACU98429.1| thiamine-phosphate diphosphorylase [Saccharomonospora viridis
DSM 43017]
Length=225
Score = 250 bits (638), Expect = 1e-64, Method: Compositional matrix adjust.
Identities = 137/218 (63%), Positives = 158/218 (73%), Gaps = 6/218 (2%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RLA A+LYLCTDAR GDLA+F +AALAGGVDI+QLRDK PL+A E+ A
Sbjct 11 KRLADAKLYLCTDARLPHGDLAEFVDAALAGGVDIVQLRDKTG-----GAPLEAAQEIEA 65
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
EILA A R+GAL AVNDRAD+A A ADVLHLGQ DLPV+VAR+I+ +IGRSTH
Sbjct 66 LEILAQACARHGALLAVNDRADVALAVDADVLHLGQNDLPVSVARRIIGERPVIGRSTHS 125
Query 124 PDQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+Q AA+ + DYFCVGPCWPTPTKPGR APGL LVR A+ +PWFAIGGI+ Q
Sbjct 126 LEQARAASVEEGVDYFCVGPCWPTPTKPGRPAPGLDLVRAVADGIETSRPWFAIGGIDRQ 185
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTA 220
RL V++AGA R+VVVRAIT ADDP AA LR L A
Sbjct 186 RLDKVVEAGAHRVVVVRAITEADDPAEAARALRDGLVA 223
>gi|29832641|ref|NP_827275.1| thiamine-phosphate pyrophosphorylase [Streptomyces avermitilis
MA-4680]
gi|29609761|dbj|BAC73810.1| putative thiamine-phosphate pyrophosphorylase [Streptomyces avermitilis
MA-4680]
Length=225
Score = 246 bits (629), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 137/218 (63%), Positives = 158/218 (73%), Gaps = 11/218 (5%)
Query 5 RLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAAC 64
RLA AR+YLCTDARR +GDLA+F +AALAGGVDI+QLRDKG ++A +EL
Sbjct 18 RLADARVYLCTDARRRQGDLAEFLDAALAGGVDIVQLRDKG---------MEAAEELEHL 68
Query 65 EILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDP 124
++ ADA R+G L AVNDRAD+A A +DVLHLGQ DLPV AR IL D LIGRSTH
Sbjct 69 QVFADACRRHGKLLAVNDRADVAHAVDSDVLHLGQGDLPVPAARAILGADVLIGRSTHAE 128
Query 125 DQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
+ AAA + DYFC GPCWPTPTKPGR APGL LVR A L G D+PWFAIGGI+
Sbjct 129 AEAEAAAVQEGVDYFCTGPCWPTPTKPGRHAPGLDLVRHTAAL-GTDRPWFAIGGIDLGN 187
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
L VL+AGARR+VVVRAIT ADDP+AAAE+ L A
Sbjct 188 LDEVLEAGARRVVVVRAITEADDPKAAAEEFAKRLRHA 225
>gi|41018323|sp|Q82AF9.2|THIE_STRAW RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
Length=215
Score = 246 bits (627), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 137/218 (63%), Positives = 158/218 (73%), Gaps = 11/218 (5%)
Query 5 RLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAAC 64
RLA AR+YLCTDARR +GDLA+F +AALAGGVDI+QLRDKG ++A +EL
Sbjct 8 RLADARVYLCTDARRRQGDLAEFLDAALAGGVDIVQLRDKG---------MEAAEELEHL 58
Query 65 EILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDP 124
++ ADA R+G L AVNDRAD+A A +DVLHLGQ DLPV AR IL D LIGRSTH
Sbjct 59 QVFADACRRHGKLLAVNDRADVAHAVDSDVLHLGQGDLPVPAARAILGADVLIGRSTHAE 118
Query 125 DQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
+ AAA + DYFC GPCWPTPTKPGR APGL LVR A LG D+PWFAIGGI+
Sbjct 119 AEAEAAAVQEGVDYFCTGPCWPTPTKPGRHAPGLDLVRHTAALGT-DRPWFAIGGIDLGN 177
Query 184 LPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
L VL+AGARR+VVVRAIT ADDP+AAAE+ L A
Sbjct 178 LDEVLEAGARRVVVVRAITEADDPKAAAEEFAKRLRHA 215
>gi|331699486|ref|YP_004335725.1| Thiamine-phosphate pyrophosphorylase [Pseudonocardia dioxanivorans
CB1190]
gi|326954175|gb|AEA27872.1| Thiamine-phosphate pyrophosphorylase [Pseudonocardia dioxanivorans
CB1190]
Length=221
Score = 245 bits (626), Expect = 3e-63, Method: Compositional matrix adjust.
Identities = 147/216 (69%), Positives = 169/216 (79%), Gaps = 7/216 (3%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RLA ARLYLCTDARRERGDLA+FA+A L+GGVD+IQLRDKGS G PL+AR+ELAA
Sbjct 10 ARLADARLYLCTDARRERGDLAEFADAVLSGGVDVIQLRDKGSDG-----PLEAREELAA 64
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
EILADA R+GAL AVNDRAD+A AAGADVLHLGQ DLPV AR+++ D ++GRS H
Sbjct 65 LEILADACARHGALLAVNDRADVALAAGADVLHLGQDDLPVEWARRVVGDDVVVGRSAHS 124
Query 124 PDQVAAAAAG-DADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
D+ A AAA DYFC GPCWPTPTKPGR APGLGLVR A+ ++PWFAIGGI+
Sbjct 125 ADETATAAAEPGVDYFCAGPCWPTPTKPGRPAPGLGLVRTVADR-KPERPWFAIGGIDHD 183
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSAL 218
RL VL AGA RIVVVR +T A+DPRAAA+ L S L
Sbjct 184 RLDEVLAAGAERIVVVRVLTEAEDPRAAAQSLSSRL 219
>gi|343924497|ref|ZP_08764046.1| thiamine-phosphate pyrophosphorylase [Gordonia alkanivorans NBRC
16433]
gi|343765641|dbj|GAA10972.1| thiamine-phosphate pyrophosphorylase [Gordonia alkanivorans NBRC
16433]
Length=265
Score = 243 bits (620), Expect = 1e-62, Method: Compositional matrix adjust.
Identities = 132/196 (68%), Positives = 147/196 (75%), Gaps = 2/196 (1%)
Query 5 RLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAAC 64
RL SARLYLCTDARRERGDL F +ALAGGVDI+QLRDKGS GE +FG L+AR+EL
Sbjct 52 RLDSARLYLCTDARRERGDLLDFVGSALAGGVDIVQLRDKGSAGEKKFGTLEAREELEIL 111
Query 65 EILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDP 124
L +GAL AVNDRADIA +GADVLH+GQ DLP VAR+I+ PDT+IG STHD
Sbjct 112 AALRGVVDAHGALLAVNDRADIAALSGADVLHVGQGDLPPEVARRIVGPDTIIGASTHDR 171
Query 125 DQVAAAAAG-DADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQR 183
+Q AAA A D DYFCVGPCW TPTKPGR+A GL LV A KPWFAIGGI+A R
Sbjct 172 EQAAAATADPDVDYFCVGPCWTTPTKPGRSAAGLDLVTTTAG-AAPGKPWFAIGGIDAPR 230
Query 184 LPAVLDAGARRIVVVR 199
+P V AGARRIVVVR
Sbjct 231 VPEVTAAGARRIVVVR 246
>gi|254382616|ref|ZP_04997974.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. Mg1]
gi|194341519|gb|EDX22485.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. Mg1]
Length=212
Score = 241 bits (614), Expect = 8e-62, Method: Compositional matrix adjust.
Identities = 131/212 (62%), Positives = 151/212 (72%), Gaps = 11/212 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+L+ ARLYLCTDAR+ +GDL +F +A LAGGVD++QLRDKG ++A +EL
Sbjct 2 QQLSDARLYLCTDARKRQGDLPEFLDAVLAGGVDVVQLRDKG---------MEAGEELEH 52
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
+ ADAA R+G L AVNDRAD+A A G+DVLHLGQ D+PV AR IL D LIGRS H
Sbjct 53 LRVFADAARRHGKLLAVNDRADVAHAIGSDVLHLGQGDIPVPAARAILGEDLLIGRSCHA 112
Query 124 PDQV-AAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+V AA A DYFC GPCWPTPTKPGR APGLGLVR AA L D+PWFAIGGI+
Sbjct 113 ESEVDAAVAEPGVDYFCTGPCWPTPTKPGRHAPGLGLVRYAASL-AQDRPWFAIGGIDGT 171
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQL 214
L VLDAGA RIVVVRA+T A DP AAA L
Sbjct 172 NLDEVLDAGATRIVVVRALTEASDPGAAAADL 203
>gi|326384629|ref|ZP_08206307.1| thiamine-phosphate pyrophosphorylase [Gordonia neofelifaecis
NRRL B-59395]
gi|326196596|gb|EGD53792.1| thiamine-phosphate pyrophosphorylase [Gordonia neofelifaecis
NRRL B-59395]
Length=225
Score = 240 bits (613), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 133/215 (62%), Positives = 153/215 (72%), Gaps = 2/215 (0%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RL +ARLYLCTDARRE GDL +F AA+ GGVDI+QLRDK SPGE FG L +EL
Sbjct 5 TRLDTARLYLCTDARRELGDLVEFVRAAVDGGVDIVQLRDKNSPGEREFGELTVAEELDL 64
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
L + GAL AVNDRADIA AAGADVLH+GQ DLP + AR+I+ PD +IGRSTH
Sbjct 65 LGRLRELTQAAGALLAVNDRADIAVAAGADVLHIGQDDLPPSHARRIVGPDVVIGRSTHS 124
Query 124 PDQ-VAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+Q + AAA D DYFC GPCW TPTKPGRAA GLGLV A+ KPWFAIGGI+
Sbjct 125 VEQALEAAADDDVDYFCTGPCWTTPTKPGRAATGLGLVASTAD-ARPSKPWFAIGGIDLP 183
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSA 217
R+ V AGA RIVVVRA+T A DP AA L++A
Sbjct 184 RVAEVTAAGAERIVVVRALTGAADPAGAARDLKAA 218
>gi|256395128|ref|YP_003116692.1| thiamine-phosphate pyrophosphorylase [Catenulispora acidiphila
DSM 44928]
gi|256361354|gb|ACU74851.1| thiamine-phosphate pyrophosphorylase [Catenulispora acidiphila
DSM 44928]
Length=218
Score = 239 bits (610), Expect = 2e-61, Method: Compositional matrix adjust.
Identities = 132/219 (61%), Positives = 155/219 (71%), Gaps = 11/219 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
++L+ ARLYLC DAR ++GDL QF +A L+GGVDI+QLR KG ++AR ELAA
Sbjct 9 TKLSDARLYLCCDAREQQGDLPQFLDAVLSGGVDIVQLRQKG---------MEARQELAA 59
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E+ ADA R+G L AVNDRADIA AGAD+LHLGQ DLPV +AR I+ LIGRS H
Sbjct 60 LEVFADACRRHGKLLAVNDRADIALGAGADILHLGQDDLPVPLARHIIGEQPLIGRSCHA 119
Query 124 PDQV-AAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGD-DKPWFAIGGINA 181
+V AAAA DYFC GP WPTPTKPGR APGLGLV+ AA L + +PWFAIGGI+
Sbjct 120 EAEVDQAAAAPGVDYFCTGPVWPTPTKPGRFAPGLGLVKYAARLAPEGTRPWFAIGGIDT 179
Query 182 QRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTA 220
L VL AGARR+VVVRA+T A DP AAA +L L A
Sbjct 180 ANLDEVLTAGARRVVVVRALTEAADPHAAAVELSGRLRA 218
>gi|329940963|ref|ZP_08290243.1| thiamin phosphate pyrophosphorylase [Streptomyces griseoaurantiacus
M045]
gi|329300257|gb|EGG44155.1| thiamin phosphate pyrophosphorylase [Streptomyces griseoaurantiacus
M045]
Length=216
Score = 238 bits (606), Expect = 6e-61, Method: Compositional matrix adjust.
Identities = 132/219 (61%), Positives = 155/219 (71%), Gaps = 11/219 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RL A LYLCTDAR +GDL +F +A LA GVDI+QLRDKG ++A +ELA
Sbjct 7 ARLDEALLYLCTDARTRQGDLPEFLDAVLAAGVDIVQLRDKG---------IEAAEELAH 57
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E+ A+A R+G L AVNDRAD+A AAGADVLHLGQ DLPV AR IL L+GRSTH
Sbjct 58 LEVFAEACARHGRLLAVNDRADVAHAAGADVLHLGQGDLPVPAARAILGEGVLVGRSTHS 117
Query 124 PDQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
P + AAA D DYFC GPCWPTPTKPGR APGL LVR A L G ++PWFAIGGI+
Sbjct 118 PAEAGAAAVQDGVDYFCTGPCWPTPTKPGRPAPGLDLVRHTAAL-GTERPWFAIGGIDLG 176
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
L V++AGARR+VVVRA+T A+DP AAA + L AA
Sbjct 177 NLDEVIEAGARRVVVVRALTEAEDPGAAAAEFARRLRAA 215
>gi|297199084|ref|ZP_06916481.1| thiamine-phosphate pyrophosphorylase [Streptomyces sviceus ATCC
29083]
gi|297147287|gb|EFH28567.1| thiamine-phosphate pyrophosphorylase [Streptomyces sviceus ATCC
29083]
Length=216
Score = 235 bits (600), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 135/216 (63%), Positives = 154/216 (72%), Gaps = 11/216 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
++LA AR+YLCTDAR +GDLA F +A LAGGVDI+QLRDKG ++A +EL
Sbjct 7 TQLADARVYLCTDARGRQGDLAAFLDAVLAGGVDIVQLRDKG---------MEAAEELEH 57
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
++ ADA R+G L AVNDRAD+A A GADVLHLGQ DLPV AR IL D LIGRSTH
Sbjct 58 LQVFADACARHGKLLAVNDRADVAHAIGADVLHLGQGDLPVPAARAILGEDVLIGRSTHA 117
Query 124 PDQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+ AAAA D DYFC GPCWPTPTKPGR APGL LVR A L D+PWFAIGGI+
Sbjct 118 EAEAAAAAVQDGVDYFCTGPCWPTPTKPGRHAPGLDLVRYTAAL-RTDRPWFAIGGIDLG 176
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSAL 218
L VL+AGARR+VVVRAIT ADDP AAA + L
Sbjct 177 NLDEVLEAGARRVVVVRAITEADDPGAAAAEFAKRL 212
>gi|297562055|ref|YP_003681029.1| thiamine-phosphate pyrophosphorylase [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
gi|296846503|gb|ADH68523.1| thiamine-phosphate pyrophosphorylase [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
Length=226
Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust.
Identities = 133/205 (65%), Positives = 154/205 (76%), Gaps = 11/205 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RL ++ LYLCTDAR RGDLA+FA+AALAGGVDIIQLRDKG L+AR+E+AA
Sbjct 14 KRLDASLLYLCTDARTGRGDLAEFADAALAGGVDIIQLRDKG---------LEAREEIAA 64
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E++ +A RYGAL AVNDRADIARA ADVLHLGQRDLPV +AR I+ D +IGRS +D
Sbjct 65 LEVMKEACERYGALLAVNDRADIARAVRADVLHLGQRDLPVPMARDIIGADPVIGRSNND 124
Query 124 PDQVAAAAAG-DADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
AA+A +DYFCVGP W TPTKPGR A GL LV AA LG D+PWFAIGGI+
Sbjct 125 VAAAAASAEEPGSDYFCVGPTWATPTKPGRPAAGLELVEEAAALGT-DRPWFAIGGIDVD 183
Query 183 RLPAVLDAGARRIVVVRAITSADDP 207
+ VLDAGARR+VVVRAIT A+DP
Sbjct 184 NIDRVLDAGARRVVVVRAITEAEDP 208
>gi|291444029|ref|ZP_06583419.1| thiamine-phosphate pyrophosphorylase [Streptomyces roseosporus
NRRL 15998]
gi|291346976|gb|EFE73880.1| thiamine-phosphate pyrophosphorylase [Streptomyces roseosporus
NRRL 15998]
Length=219
Score = 234 bits (598), Expect = 5e-60, Method: Compositional matrix adjust.
Identities = 133/212 (63%), Positives = 150/212 (71%), Gaps = 11/212 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+L+ ARLYLCTDAR+ +GDL F +A L GVDI+QLRDKG ++A +EL
Sbjct 9 EQLSDARLYLCTDARKRQGDLPAFLDAVLTSGVDIVQLRDKG---------MEAAEELDH 59
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
+ ADA R+G L AVNDRAD+A A GADVLHLGQ DLPV AR I+ LIGRSTH
Sbjct 60 LAVFADACRRHGKLLAVNDRADVAHAIGADVLHLGQGDLPVPAARAIIGDGRLIGRSTHA 119
Query 124 PDQVAAAAAGDA-DYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+V AA A D DYFC GPCWPTPTKPGR APGLGLVR AA L G +PWFAIGGI A
Sbjct 120 EAEVDAAVAQDGVDYFCTGPCWPTPTKPGRHAPGLGLVRYAASL-GSPRPWFAIGGIGAG 178
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQL 214
L VLDAGARR+VVVRAIT ADDP AA +L
Sbjct 179 NLDQVLDAGARRVVVVRAITEADDPAAATAEL 210
>gi|302561103|ref|ZP_07313445.1| thiamine-phosphate pyrophosphorylase [Streptomyces griseoflavus
Tu4000]
gi|302478721|gb|EFL41814.1| thiamine-phosphate pyrophosphorylase [Streptomyces griseoflavus
Tu4000]
Length=225
Score = 234 bits (598), Expect = 6e-60, Method: Compositional matrix adjust.
Identities = 136/220 (62%), Positives = 156/220 (71%), Gaps = 11/220 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RLA AR+YLCTDARR +GDLA+F +A LAGGVDI+QLRDKG ++A +EL
Sbjct 12 ARLADARVYLCTDARRRQGDLAEFLDAVLAGGVDIVQLRDKG---------MEAGEELEH 62
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
+LADA R+G L AVNDRAD+A AAGADVLHLGQ DLPV AR +L LIGRSTH
Sbjct 63 LAVLADACARHGRLLAVNDRADVAHAAGADVLHLGQGDLPVPAARALLGDGVLIGRSTHA 122
Query 124 PDQVAAAAAG-DADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+ AAAA DYFC GPCWPTPTKPGR APGL LVR A L ++PWFAIGGI+
Sbjct 123 ESEAAAAAVQPGVDYFCTGPCWPTPTKPGRHAPGLDLVRYTAAL-APERPWFAIGGIDLG 181
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN 222
L VLDAGARR+VVVRA+T ADDP AAA + L A
Sbjct 182 NLDEVLDAGARRVVVVRALTEADDPGAAAAEFAKRLRQAE 221
>gi|72161450|ref|YP_289107.1| thiamine-phosphate pyrophosphorylase [Thermobifida fusca YX]
gi|123629789|sp|Q47R33.1|THIE_THEFY RecName: Full=Thiamine-phosphate pyrophosphorylase; Short=TMP
pyrophosphorylase; Short=TMP-PPase; AltName: Full=Thiamine-phosphate
synthase
gi|71915182|gb|AAZ55084.1| thiamine monophosphate synthase [Thermobifida fusca YX]
Length=218
Score = 234 bits (597), Expect = 7e-60, Method: Compositional matrix adjust.
Identities = 138/219 (64%), Positives = 154/219 (71%), Gaps = 11/219 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
RL SARLYLCTDAR +RGDLA+F +AALAGGVDI+QLRDK L ARDELAA
Sbjct 7 KRLESARLYLCTDARADRGDLAEFLDAALAGGVDIVQLRDK---------TLDARDELAA 57
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E++ +A R+GAL AVNDRADIA A ADVLHLGQRDLPV AR IL LIGRST+
Sbjct 58 LEVVREACDRHGALLAVNDRADIAHAVNADVLHLGQRDLPVRYARAILGDRPLIGRSTNA 117
Query 124 PDQVAAAAAGD-ADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+ AAA + DYFC+GP W TPTKPGR A GL V A L +PWFAIGGIN
Sbjct 118 AELSAAADREEGVDYFCIGPVWATPTKPGRPAAGLDEVARVAALHP-QRPWFAIGGINED 176
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAA 221
L VL AGARR VVVRAIT A+DPRAAA +L+ L AA
Sbjct 177 NLDQVLAAGARRAVVVRAITEAEDPRAAAAELKRRLVAA 215
>gi|300790385|ref|YP_003770676.1| thiamine-phosphate pyrophosphorylase [Amycolatopsis mediterranei
U32]
gi|299799899|gb|ADJ50274.1| thiamine-phosphate pyrophosphorylase [Amycolatopsis mediterranei
U32]
gi|340532069|gb|AEK47274.1| thiamine-phosphate pyrophosphorylase [Amycolatopsis mediterranei
S699]
Length=219
Score = 234 bits (597), Expect = 7e-60, Method: Compositional matrix adjust.
Identities = 144/216 (67%), Positives = 165/216 (77%), Gaps = 9/216 (4%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+RL SARLYLCTDAR RGDLA FA+AALAGGVDI+QLRDK G L+A E+AA
Sbjct 11 ARLDSARLYLCTDARTNRGDLAAFADAALAGGVDIVQLRDK-------TGALEAAGEIAA 63
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
E+LA+A R+GAL +VNDRAD+A A GADVLHLGQ D+PV +AR+IL + +IGRSTH
Sbjct 64 LEVLAEACARHGALLSVNDRADVALAVGADVLHLGQDDIPVPLARRILGDEVVIGRSTHS 123
Query 124 PDQ-VAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
DQ +AAAA DYFC GPCWPTPTKPGR APGL LVR A D+PWFAIGGI+
Sbjct 124 LDQALAAAAEPGVDYFCTGPCWPTPTKPGRPAPGLDLVRATAAW-TPDRPWFAIGGIDGP 182
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSAL 218
RLP VLDAGA RIVVVRAIT A+DP AAA +LR+ L
Sbjct 183 RLPEVLDAGASRIVVVRAITEAEDPEAAARELRARL 218
>gi|302533974|ref|ZP_07286316.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. C]
gi|302442869|gb|EFL14685.1| thiamine-phosphate pyrophosphorylase [Streptomyces sp. C]
Length=212
Score = 234 bits (596), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 128/212 (61%), Positives = 149/212 (71%), Gaps = 11/212 (5%)
Query 4 SRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAA 63
+L+ ARLYLCTDAR+ +GDL +F +A LAGGVDI+QLRDKG ++A +EL
Sbjct 2 QQLSDARLYLCTDARKRQGDLPEFLDAVLAGGVDIVQLRDKG---------MEAGEELDH 52
Query 64 CEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHD 123
+ A+AA R+G L AVNDRAD+A A G+DVLHLGQ D+PV AR IL LIGRS H
Sbjct 53 LRVFAEAARRHGKLLAVNDRADVAHAIGSDVLHLGQGDIPVPAARAILGDGVLIGRSCHA 112
Query 124 PDQV-AAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQ 182
+V AA A DYFC GPCWPTPTKPGR APGL LVR A L D+PWFAIGGI+
Sbjct 113 ESEVDAAVAEPGVDYFCTGPCWPTPTKPGRHAPGLDLVRYTASL-AQDRPWFAIGGIDGG 171
Query 183 RLPAVLDAGARRIVVVRAITSADDPRAAAEQL 214
L VLDAGA R+VVVRAIT A DP AAA +L
Sbjct 172 NLDEVLDAGATRVVVVRAITEATDPGAAAAEL 203
Lambda K H
0.321 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 279760868288
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40