BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv0423c
Length=547
Score E
Sequences producing significant alignments: (Bits) Value
gi|15839810|ref|NP_334847.1| thiamine biosynthesis protein ThiC ... 1129 0.0
gi|15607564|ref|NP_214937.1| thiamine biosynthesis protein ThiC ... 1129 0.0
gi|339630492|ref|YP_004722134.1| thiamine biosynthesis protein T... 1127 0.0
gi|306774519|ref|ZP_07412856.1| thiamine biosynthesis protein th... 1127 0.0
gi|340625448|ref|YP_004743900.1| putative thiamine biosynthesis ... 1118 0.0
gi|289568339|ref|ZP_06448566.1| thiamine biosynthesis protein th... 1081 0.0
gi|289748907|ref|ZP_06508285.1| thiamine biosynthesis protein th... 1061 0.0
gi|240168895|ref|ZP_04747554.1| thiamine biosynthesis protein Th... 1037 0.0
gi|296167896|ref|ZP_06850077.1| thiamin biosynthesis protein Thi... 1022 0.0
gi|15827068|ref|NP_301331.1| thiamine biosynthesis protein ThiC ... 1019 0.0
gi|342859089|ref|ZP_08715743.1| thiamine biosynthesis protein Th... 1012 0.0
gi|183980759|ref|YP_001849050.1| thiamine biosynthesis protein T... 1012 0.0
gi|118618879|ref|YP_907211.1| thiamine biosynthesis protein ThiC... 1010 0.0
gi|118465494|ref|YP_883858.1| thiamine biosynthesis protein ThiC... 999 0.0
gi|254818956|ref|ZP_05223957.1| thiamine biosynthesis protein Th... 999 0.0
gi|41410011|ref|NP_962847.1| thiamine biosynthesis protein ThiC ... 998 0.0
gi|336460346|gb|EGO39246.1| thiamine biosynthesis protein ThiC [... 986 0.0
gi|333989035|ref|YP_004521649.1| thiamine biosynthesis protein T... 976 0.0
gi|169631274|ref|YP_001704923.1| thiamine biosynthesis protein T... 937 0.0
gi|118467543|ref|YP_885230.1| thiamine biosynthesis protein ThiC... 932 0.0
gi|333918222|ref|YP_004491803.1| phosphomethylpyrimidine synthas... 917 0.0
gi|226361311|ref|YP_002779089.1| thiamine biosynthesis protein T... 911 0.0
gi|111019175|ref|YP_702147.1| thiamine biosynthesis protein ThiC... 910 0.0
gi|120401740|ref|YP_951569.1| thiamine biosynthesis protein ThiC... 900 0.0
gi|326383427|ref|ZP_08205114.1| thiamine biosynthesis protein Th... 898 0.0
gi|343924277|ref|ZP_08763836.1| phosphomethylpyrimidine synthase... 892 0.0
gi|262200661|ref|YP_003271869.1| thiamine biosynthesis protein T... 892 0.0
gi|145221349|ref|YP_001132027.1| thiamine biosynthesis protein T... 888 0.0
gi|315441767|ref|YP_004074646.1| hydroxymethylpyrimidine synthas... 886 0.0
gi|54027290|ref|YP_121532.1| thiamine biosynthesis protein ThiC ... 873 0.0
gi|284028926|ref|YP_003378857.1| thiamine biosynthesis protein T... 871 0.0
gi|257057415|ref|YP_003135247.1| thiamine biosynthesis protein T... 870 0.0
gi|297562633|ref|YP_003681607.1| thiamine biosynthesis protein T... 865 0.0
gi|296141411|ref|YP_003648654.1| thiamine biosynthesis protein T... 863 0.0
gi|302530617|ref|ZP_07282959.1| ThiC protein [Streptomyces sp. A... 860 0.0
gi|325002845|ref|ZP_08123957.1| thiamine biosynthesis protein Th... 858 0.0
gi|134097122|ref|YP_001102783.1| thiamine biosynthesis protein T... 857 0.0
gi|334563417|ref|ZP_08516408.1| thiamine biosynthesis protein Th... 855 0.0
gi|300790377|ref|YP_003770668.1| thiamine biosynthesis protein T... 855 0.0
gi|317506799|ref|ZP_07964574.1| ThiC family protein [Segniliparu... 848 0.0
gi|256374578|ref|YP_003098238.1| thiamine biosynthesis protein T... 845 0.0
gi|213964640|ref|ZP_03392840.1| thiamine biosynthesis protein Th... 842 0.0
gi|291009661|ref|ZP_06567634.1| thiamine biosynthesis protein Th... 838 0.0
gi|296393667|ref|YP_003658551.1| thiamine biosynthesis protein T... 837 0.0
gi|226304977|ref|YP_002764935.1| thiamine biosynthesis protein T... 832 0.0
gi|331699884|ref|YP_004336123.1| phosphomethylpyrimidine synthas... 815 0.0
gi|288923395|ref|ZP_06417523.1| thiamine biosynthesis protein Th... 801 0.0
gi|158317358|ref|YP_001509866.1| thiamine biosynthesis protein T... 798 0.0
gi|345016397|ref|YP_004818751.1| phosphomethylpyrimidine synthas... 792 0.0
gi|336177350|ref|YP_004582725.1| phosphomethylpyrimidine synthas... 791 0.0
>gi|15839810|ref|NP_334847.1| thiamine biosynthesis protein ThiC [Mycobacterium tuberculosis
CDC1551]
gi|13879941|gb|AAK44661.1| thiamin biosynthesis protein ThiC [Mycobacterium tuberculosis
CDC1551]
Length=549
Score = 1129 bits (2920), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 547/547 (100%), Positives = 547/547 (100%), Gaps = 0/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
Sbjct 3 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 62
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
Sbjct 63 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 122
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 123 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 182
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 183 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 242
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 243 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 302
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 303 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 362
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 363 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 422
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 423 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 482
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR
Sbjct 483 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 542
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 543 VYLPITQ 549
>gi|15607564|ref|NP_214937.1| thiamine biosynthesis protein ThiC [Mycobacterium tuberculosis
H37Rv]
gi|31791601|ref|NP_854094.1| thiamine biosynthesis protein ThiC [Mycobacterium bovis AF2122/97]
gi|121636337|ref|YP_976560.1| thiamine biosynthesis protein ThiC [Mycobacterium bovis BCG str.
Pasteur 1173P2]
67 more sequence titles
Length=547
Score = 1129 bits (2920), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 547/547 (100%), Positives = 547/547 (100%), Gaps = 0/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
Sbjct 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
Sbjct 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR
Sbjct 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 541 VYLPITQ 547
>gi|339630492|ref|YP_004722134.1| thiamine biosynthesis protein ThiC [Mycobacterium africanum GM041182]
gi|339329848|emb|CCC25497.1| putative thiamine biosynthesis protein THIC [Mycobacterium africanum
GM041182]
Length=547
Score = 1127 bits (2915), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 546/547 (99%), Positives = 546/547 (99%), Gaps = 0/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRV LSTGDHFDLYDTSGPYTDT
Sbjct 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVQLSTGDHFDLYDTSGPYTDT 60
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
Sbjct 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR
Sbjct 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 541 VYLPITQ 547
>gi|306774519|ref|ZP_07412856.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
SUMu001]
gi|306970623|ref|ZP_07483284.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
SUMu010]
gi|307078349|ref|ZP_07487519.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
SUMu011]
gi|308216868|gb|EFO76267.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
SUMu001]
gi|308359745|gb|EFP48596.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
SUMu010]
gi|308363686|gb|EFP52537.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
SUMu011]
Length=547
Score = 1127 bits (2914), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 546/547 (99%), Positives = 547/547 (100%), Gaps = 0/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
Sbjct 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
Sbjct 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPAN+HHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 121 IPANYHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR
Sbjct 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 541 VYLPITQ 547
>gi|340625448|ref|YP_004743900.1| putative thiamine biosynthesis protein THIC [Mycobacterium canettii
CIPT 140010059]
gi|340003638|emb|CCC42761.1| putative thiamine biosynthesis protein THIC [Mycobacterium canettii
CIPT 140010059]
Length=547
Score = 1118 bits (2893), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 542/547 (99%), Positives = 544/547 (99%), Gaps = 0/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAGS+KAYREIEAPGS ATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
Sbjct 1 MTITVEPSVTTGPIAGSSKAYREIEAPGSRATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDM AELVRDEVARGRAV
Sbjct 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMPAELVRDEVARGRAV 120
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANH+HPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 121 IPANHNHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETE DIEAVLAAGMAEKSREFAEHGNR
Sbjct 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEEDIEAVLAAGMAEKSREFAEHGNR 540
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 541 VYLPITQ 547
>gi|289568339|ref|ZP_06448566.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
T17]
gi|289542092|gb|EFD45741.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
T17]
Length=546
Score = 1081 bits (2796), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 539/547 (99%), Positives = 539/547 (99%), Gaps = 1/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAG A A PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
Sbjct 1 MTITVEPSVTTGPIAGYATASLRGR-PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 59
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
Sbjct 60 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 119
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 120 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 179
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 180 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 239
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 240 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 299
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 300 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 359
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 360 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 419
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 420 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 479
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR
Sbjct 480 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 539
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 540 VYLPITQ 546
>gi|289748907|ref|ZP_06508285.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
T92]
gi|289689494|gb|EFD56923.1| thiamine biosynthesis protein thiC [Mycobacterium tuberculosis
T92]
Length=513
Score = 1061 bits (2745), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 513/513 (100%), Positives = 513/513 (100%), Gaps = 0/513 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT
Sbjct 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV
Sbjct 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG
Sbjct 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
Sbjct 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGL 513
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGL
Sbjct 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGL 513
>gi|240168895|ref|ZP_04747554.1| thiamine biosynthesis protein ThiC [Mycobacterium kansasii ATCC
12478]
Length=548
Score = 1037 bits (2682), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 517/551 (94%), Positives = 533/551 (97%), Gaps = 8/551 (1%)
Query 1 MTITVEPS---VTTGPIAGSAKAYREIEA-PGSGATLQVPFRRVHLSTGDHFDLYDTSGP 56
MT+T EPS VTTGPIAGS+KAYR ++ PG+ +VPFRRVHLSTGDHFDLYDTSGP
Sbjct 1 MTLTTEPSAPSVTTGPIAGSSKAYRTLDGVPGA----RVPFRRVHLSTGDHFDLYDTSGP 56
Query 57 YTDTDTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVAR 116
YTD DTVIDLTAGLP RP VVRDRGTQLQRARAGEITAEMAFIA+RE M AELVRDEVAR
Sbjct 57 YTDPDTVIDLTAGLPARPAVVRDRGTQLQRARAGEITAEMAFIASREGMPAELVRDEVAR 116
Query 117 GRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMD 176
GRAVIPANH+HPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMD
Sbjct 117 GRAVIPANHNHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMD 176
Query 177 LSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDY 236
LSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDY
Sbjct 177 LSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDY 236
Query 237 MTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVT 296
MTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+F+ELCDIFARYDVT
Sbjct 237 MTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFDELCDIFARYDVT 296
Query 297 FSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRL 356
FSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHG+QVMIEGPGHIPMHKIVENVRL
Sbjct 297 FSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGSQVMIEGPGHIPMHKIVENVRL 356
Query 357 EEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKD 416
EEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKD
Sbjct 357 EEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKD 416
Query 417 VKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDET 476
VKDGVIAYKIAAH+ADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDET
Sbjct 417 VKDGVIAYKIAAHSADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDET 476
Query 477 LPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAE 536
LPAEPAKTAHFCSMCGPKFCSMRITQDVR++AA+HGLETE DIEA+LA GMAEKSREFAE
Sbjct 477 LPAEPAKTAHFCSMCGPKFCSMRITQDVRDFAAKHGLETEEDIEAMLAEGMAEKSREFAE 536
Query 537 HGNRVYLPITQ 547
HGNRVYLPITQ
Sbjct 537 HGNRVYLPITQ 547
>gi|296167896|ref|ZP_06850077.1| thiamin biosynthesis protein ThiC [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295896954|gb|EFG76579.1| thiamin biosynthesis protein ThiC [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=548
Score = 1022 bits (2643), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 507/545 (94%), Positives = 523/545 (96%), Gaps = 5/545 (0%)
Query 4 TVEPSVTTGPIAGSAKAYREIEA-PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDT 62
TV+ SVTTGPIAGS+K YRE++ PG+ +VPFRRVHLSTGDHFDLYDTSGPYTD D
Sbjct 8 TVDASVTTGPIAGSSKVYRELDGFPGA----RVPFRRVHLSTGDHFDLYDTSGPYTDADA 63
Query 63 VIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIP 122
VIDL +GL RPGVVRDRGTQLQRARAGEITAEMA+IAAREDM AELVRDEVARGRAVIP
Sbjct 64 VIDLASGLSPRPGVVRDRGTQLQRARAGEITAEMAYIAAREDMPAELVRDEVARGRAVIP 123
Query 123 ANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKN 182
ANH+HPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG+N
Sbjct 124 ANHNHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGRN 183
Query 183 IHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAG 242
IHETREWILRNSPVPVGTVPIYQALEKV GDPT LTWEIYRDTVIEQCEQGVDYMTVHAG
Sbjct 184 IHETREWILRNSPVPVGTVPIYQALEKVNGDPTALTWEIYRDTVIEQCEQGVDYMTVHAG 243
Query 243 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDG 302
VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHH ESFLYTNFEELCDIFARYDVTFSLGDG
Sbjct 244 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHTESFLYTNFEELCDIFARYDVTFSLGDG 303
Query 303 LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCE 362
LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGH+PMHKIVENVRLEEELCE
Sbjct 304 LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHVPMHKIVENVRLEEELCE 363
Query 363 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 422
EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI
Sbjct 364 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 423
Query 423 AYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA 482
AYKIAAH+ADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA
Sbjct 424 AYKIAAHSADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA 483
Query 483 KTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVY 542
KTAHFCSMCGPKFCSMRIT DVR YAAEHGL++E IEAV++ GMAEKSREFAEHGNRVY
Sbjct 484 KTAHFCSMCGPKFCSMRITADVRAYAAEHGLDSEEAIEAVMSEGMAEKSREFAEHGNRVY 543
Query 543 LPITQ 547
LPITQ
Sbjct 544 LPITQ 548
>gi|15827068|ref|NP_301331.1| thiamine biosynthesis protein ThiC [Mycobacterium leprae TN]
gi|221229546|ref|YP_002502962.1| thiamine biosynthesis protein ThiC [Mycobacterium leprae Br4923]
gi|7388313|sp|Q9ZBL0.1|THIC_MYCLE RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|254784167|sp|B8ZU90.1|THIC_MYCLB RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|4154058|emb|CAA22712.1| putative thiamine biosythesis protein ThiC [Mycobacterium leprae]
gi|13092616|emb|CAC29802.1| putative thiamine biosynthesis protein [Mycobacterium leprae]
gi|219932653|emb|CAR70387.1| putative thiamine biosynthesis protein [Mycobacterium leprae
Br4923]
Length=547
Score = 1019 bits (2634), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 493/547 (91%), Positives = 513/547 (94%), Gaps = 4/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
++ T EPSVTTGPI GS+KAYRE+ P G +L+VPFRRVHLSTG HFDLYDTSGPYTD
Sbjct 5 LSKTTEPSVTTGPIPGSSKAYREVANPDGGPSLRVPFRRVHLSTGAHFDLYDTSGPYTDP 64
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
D VI+LTAGLP RPGV+RDRGTQLQRARAGEITAEMAFIA RE M AELVR EVA GRAV
Sbjct 65 DAVINLTAGLPPRPGVIRDRGTQLQRARAGEITAEMAFIADREGMPAELVRVEVALGRAV 124
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANH+HPE EPMIIGKAFAVKVNANIGNSAVTSSIAEE+DKMVWATRWGADTIMDLSTG
Sbjct 125 IPANHNHPEIEPMIIGKAFAVKVNANIGNSAVTSSIAEEIDKMVWATRWGADTIMDLSTG 184
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPT+LTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 185 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTKLTWEIYRDTVIEQCEQGVDYMTVH 244
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYV LTAKRVTGIVSRGGSIMA+WCLA+HRESFLYTNF ELCDIFARYDVTFSLG
Sbjct 245 AGVLLRYVLLTAKRVTGIVSRGGSIMASWCLANHRESFLYTNFAELCDIFARYDVTFSLG 304
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADAND AQFAELRTLGEL+KIAK HGAQVMIEGPGHIPMHKIVENVRLEEEL
Sbjct 305 DGLRPGSIADANDTAQFAELRTLGELSKIAKVHGAQVMIEGPGHIPMHKIVENVRLEEEL 364
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 365 CEEAPFYTLGPLATDIAPAYDHITSAIGAAVIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 424
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHAADLAKG+PRAQERDDALSTARFEFRWNDQFALSLDP TAREFHDETLPAE
Sbjct 425 VIAYKIAAHAADLAKGYPRAQERDDALSTARFEFRWNDQFALSLDPPTAREFHDETLPAE 484
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRIT D+R YAA+HGL+TE IE GM EKS EFAEHGNR
Sbjct 485 PAKTAHFCSMCGPKFCSMRITADIRVYAAKHGLDTEEAIE----MGMTEKSAEFAEHGNR 540
Query 541 VYLPITQ 547
VYLP+TQ
Sbjct 541 VYLPLTQ 547
>gi|342859089|ref|ZP_08715743.1| thiamine biosynthesis protein ThiC [Mycobacterium colombiense
CECT 3035]
gi|342133330|gb|EGT86533.1| thiamine biosynthesis protein ThiC [Mycobacterium colombiense
CECT 3035]
Length=551
Score = 1012 bits (2617), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 499/544 (92%), Positives = 516/544 (95%), Gaps = 1/544 (0%)
Query 4 TVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTV 63
TV+ SVTTGPIAGS+KAYREIE P G TL+VP RRVHLSTGD FDLYDTSGPYTD D
Sbjct 8 TVDASVTTGPIAGSSKAYREIEGP-DGVTLRVPLRRVHLSTGDDFDLYDTSGPYTDPDAT 66
Query 64 IDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPA 123
IDLTAGLP RPGVVRDRGTQLQRARAGEITAEMA+IAARE M AELVRDEVARGRAVIPA
Sbjct 67 IDLTAGLPARPGVVRDRGTQLQRARAGEITAEMAYIAAREGMPAELVRDEVARGRAVIPA 126
Query 124 NHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNI 183
NH+HPE EPMIIGKAFA KVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNI
Sbjct 127 NHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNI 186
Query 184 HETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGV 243
HETREWILRNSPVPVGTVPIYQALEK KGDPTELTWE+YRDTVIEQCEQGVDYMTVHAGV
Sbjct 187 HETREWILRNSPVPVGTVPIYQALEKTKGDPTELTWELYRDTVIEQCEQGVDYMTVHAGV 246
Query 244 LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGL 303
LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELC+IFARYDVTFSLGDGL
Sbjct 247 LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCEIFARYDVTFSLGDGL 306
Query 304 RPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEE 363
RPGSIADANDAAQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEE CEE
Sbjct 307 RPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEE 366
Query 364 APFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIA 423
APFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIA
Sbjct 367 APFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIA 426
Query 424 YKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAK 483
YKIAAHA DLAKGHP AQERD+ALS ARFEFRWNDQFALSLDPDTAR +HDETLPAEPAK
Sbjct 427 YKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTARSYHDETLPAEPAK 486
Query 484 TAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYL 543
TAHFCSMCGPKFCSMRITQDVR+YAA+HGL++E IEA + GMAEKSREFAEHGNRVYL
Sbjct 487 TAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAAMTEGMAEKSREFAEHGNRVYL 546
Query 544 PITQ 547
P+ Q
Sbjct 547 PLAQ 550
>gi|183980759|ref|YP_001849050.1| thiamine biosynthesis protein ThiC [Mycobacterium marinum M]
gi|238690953|sp|B2HQM5.1|THIC_MYCMM RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|183174085|gb|ACC39195.1| thiamine biosynthesis protein ThiC [Mycobacterium marinum M]
Length=546
Score = 1012 bits (2616), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 504/547 (93%), Positives = 522/547 (96%), Gaps = 1/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MT+TVEPS+TTGPIAGS+KAYRE+ P G TL+VP RRVHLSTG FDLYDTSGPYTD
Sbjct 1 MTVTVEPSITTGPIAGSSKAYREVAGP-DGVTLRVPLRRVHLSTGADFDLYDTSGPYTDP 59
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
+ VIDL GLP RPG+VRDRGTQLQRARAGEITAEMAFIAARE MSAELVRDEVA GRAV
Sbjct 60 NAVIDLAVGLPARPGLVRDRGTQLQRARAGEITAEMAFIAAREGMSAELVRDEVALGRAV 119
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANH+HPESEPM+IGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 120 IPANHNHPESEPMVIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 179
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWE+YRDTVIEQCEQGVDYMTVH
Sbjct 180 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWELYRDTVIEQCEQGVDYMTVH 239
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDI ARYDVTFSLG
Sbjct 240 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDILARYDVTFSLG 299
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHG QVMIEGPGH+PMHKIVENVRLEEEL
Sbjct 300 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEEL 359
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 360 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 419
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHA DLAKGHP AQERD+ALS ARFEFRWNDQFALSLDPDTARE+HDETLPAE
Sbjct 420 VIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAE 479
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRITQDVR+YAA+HGL++E IEA L AGMAEKS EFA+HGNR
Sbjct 480 PAKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAALEAGMAEKSAEFADHGNR 539
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 540 VYLPITQ 546
>gi|118618879|ref|YP_907211.1| thiamine biosynthesis protein ThiC [Mycobacterium ulcerans Agy99]
gi|166228048|sp|A0PTS1.1|THIC_MYCUA RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|118570989|gb|ABL05740.1| thiamine biosynthesis protein ThiC [Mycobacterium ulcerans Agy99]
Length=546
Score = 1010 bits (2611), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 503/547 (92%), Positives = 522/547 (96%), Gaps = 1/547 (0%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
MT+TVEPS+TTGPIAGS+KAYRE+ P G TL+VP RRVHLSTG FDLYDTSGPYTD
Sbjct 1 MTVTVEPSITTGPIAGSSKAYREVAGP-DGVTLRVPLRRVHLSTGADFDLYDTSGPYTDP 59
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
+ VIDL GLP RPG+VRDRGTQLQRARAGEITAEMAFIAARE MSAELVRDEVA GRAV
Sbjct 60 NAVIDLAVGLPARPGLVRDRGTQLQRARAGEITAEMAFIAAREGMSAELVRDEVALGRAV 119
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANH+HPESEPM+IGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 120 IPANHNHPESEPMVIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 179
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWE+YRDTVIEQCEQGVDYMTVH
Sbjct 180 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWELYRDTVIEQCEQGVDYMTVH 239
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDI ARYDVTFSLG
Sbjct 240 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDILARYDVTFSLG 299
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAKAHG QVMIEGPGH+PMHKIVENVRLEEEL
Sbjct 300 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEEL 359
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 360 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 419
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHA DLAKGHP AQERD+ALS ARFEFRWNDQFALSLDPDTARE+HDETLPAE
Sbjct 420 VIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAE 479
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRIT+DVR+YAA+HGL++E IEA L AGMAEKS EFA+HGNR
Sbjct 480 PAKTAHFCSMCGPKFCSMRITRDVRDYAAKHGLDSEEAIEAALEAGMAEKSAEFADHGNR 539
Query 541 VYLPITQ 547
VYLPITQ
Sbjct 540 VYLPITQ 546
>gi|118465494|ref|YP_883858.1| thiamine biosynthesis protein ThiC [Mycobacterium avium 104]
gi|254777170|ref|ZP_05218686.1| thiamine biosynthesis protein ThiC [Mycobacterium avium subsp.
avium ATCC 25291]
gi|166228045|sp|A0QLS0.1|THIC_MYCA1 RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|118166781|gb|ABK67678.1| thiamine biosynthesis protein ThiC [Mycobacterium avium 104]
Length=540
Score = 999 bits (2584), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 498/548 (91%), Positives = 516/548 (95%), Gaps = 9/548 (1%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEA-PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTD 59
MT VEPSVTTGPIAGS+K YRE++ PG+ +VPFRRVHLSTGDHFDLYDTSGPYTD
Sbjct 1 MTAIVEPSVTTGPIAGSSKVYRELDGVPGA----RVPFRRVHLSTGDHFDLYDTSGPYTD 56
Query 60 TDTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRA 119
D IDLTAGLP RPG VRDRGTQLQRARAGEITAEMAFIAARE M AELVRDEVARGRA
Sbjct 57 PDATIDLTAGLPARPGRVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRA 116
Query 120 VIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST 179
VIPANH+HPE EPMIIGKAFA KVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST
Sbjct 117 VIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST 176
Query 180 GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTV 239
GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPT LTWEIYRDTVIEQCEQGVDYMTV
Sbjct 177 GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTV 236
Query 240 HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSL 299
HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNF+ELC+IFARYDVTFSL
Sbjct 237 HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSL 296
Query 300 GDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEE 359
GDGLRPGSIADANDAAQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEE
Sbjct 297 GDGLRPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEE 356
Query 360 LCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD 419
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD
Sbjct 357 WCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD 416
Query 420 GVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPA 479
GVIAYKIAAHA DLAKGHP AQERD+ALS ARFEFRWNDQFALSLDPDTARE+HDETLPA
Sbjct 417 GVIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPA 476
Query 480 EPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGN 539
EPAKTAHFCSMCGPKFCSMRITQDVR+YAA+HGL++E IE A MA+KSREFAEHGN
Sbjct 477 EPAKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIE----AAMADKSREFAEHGN 532
Query 540 RVYLPITQ 547
RVYLP+ Q
Sbjct 533 RVYLPLAQ 540
>gi|254818956|ref|ZP_05223957.1| thiamine biosynthesis protein ThiC [Mycobacterium intracellulare
ATCC 13950]
Length=546
Score = 999 bits (2582), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 495/547 (91%), Positives = 512/547 (94%), Gaps = 6/547 (1%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
++ T PSVTTGPIAGS K YR++ A +VPFRRV LS GDHFDLYDTSGPYTD
Sbjct 5 LSGTAAPSVTTGPIAGSHKIYRDV------AGGRVPFRRVDLSNGDHFDLYDTSGPYTDP 58
Query 61 DTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
D IDL AGLP RPGVVRDRGTQLQRARAGEITAEMAFIAARE M AELVRDEVARGRAV
Sbjct 59 DATIDLAAGLPARPGVVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAV 118
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPANH+HPE EPMIIGKAFA KVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG
Sbjct 119 IPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 178
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWI+RNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 179 KNIHETREWIMRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 238
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELC+IFARYDVTFSLG
Sbjct 239 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCEIFARYDVTFSLG 298
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADANDAAQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEE
Sbjct 299 DGLRPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEW 358
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG
Sbjct 359 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 418
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VIAYKIAAHA DLAKGHP AQERD+ALS ARFEFRWNDQFALSLDPDTARE+HDETLPAE
Sbjct 419 VIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAE 478
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRIT DVR YAAEHGL++E IEAV++ GMAEKSREFAEHGNR
Sbjct 479 PAKTAHFCSMCGPKFCSMRITADVRAYAAEHGLDSEEAIEAVMSEGMAEKSREFAEHGNR 538
Query 541 VYLPITQ 547
VYLP+ Q
Sbjct 539 VYLPLAQ 545
>gi|41410011|ref|NP_962847.1| thiamine biosynthesis protein ThiC [Mycobacterium avium subsp.
paratuberculosis K-10]
gi|47606074|sp|P61426.1|THIC_MYCPA RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|41398844|gb|AAS06463.1| ThiC [Mycobacterium avium subsp. paratuberculosis K-10]
Length=540
Score = 998 bits (2581), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 497/548 (91%), Positives = 516/548 (95%), Gaps = 9/548 (1%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEA-PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTD 59
MT VEPSVTTGPIAGS+K YRE++ PG+ +VPFRRVHLSTGDHFDLYDTSGPYTD
Sbjct 1 MTAIVEPSVTTGPIAGSSKVYRELDGVPGA----RVPFRRVHLSTGDHFDLYDTSGPYTD 56
Query 60 TDTVIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRA 119
D IDLTAGLP RPG VRDRGTQLQRARAGEITAEMAFIAARE M AELVRDEVARGRA
Sbjct 57 PDATIDLTAGLPARPGRVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRA 116
Query 120 VIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST 179
VIPANH+HPE EPMIIGKAFA KVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST
Sbjct 117 VIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST 176
Query 180 GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTV 239
GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPT LTWEIYRDTVIEQCEQGVDYMTV
Sbjct 177 GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTV 236
Query 240 HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSL 299
HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNF+ELC+IFARYDVTFSL
Sbjct 237 HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSL 296
Query 300 GDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEE 359
GDGLRPGSIADANDAAQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEE
Sbjct 297 GDGLRPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEE 356
Query 360 LCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD 419
CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD
Sbjct 357 WCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD 416
Query 420 GVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPA 479
GVIAYKIAAHA DLAKGHP AQ+RD+ALS ARFEFRWNDQFALSLDPDTARE+HDETLPA
Sbjct 417 GVIAYKIAAHAGDLAKGHPHAQQRDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPA 476
Query 480 EPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGN 539
EPAKTAHFCSMCGPKFCSMRITQDVR+YAA+HGL++E IE A MA+KSREFAEHGN
Sbjct 477 EPAKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIE----AAMADKSREFAEHGN 532
Query 540 RVYLPITQ 547
RVYLP+ Q
Sbjct 533 RVYLPLAQ 540
>gi|336460346|gb|EGO39246.1| thiamine biosynthesis protein ThiC [Mycobacterium avium subsp.
paratuberculosis S397]
Length=532
Score = 986 bits (2548), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 490/540 (91%), Positives = 510/540 (95%), Gaps = 9/540 (1%)
Query 9 VTTGPIAGSAKAYREIEA-PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
+TTGPIAGS+K YRE++ PG+ +VPFRRVHLSTGDHFDLYDTSGPYTD D IDLT
Sbjct 1 MTTGPIAGSSKVYRELDGVPGA----RVPFRRVHLSTGDHFDLYDTSGPYTDPDATIDLT 56
Query 68 AGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHH 127
AGLP RPG VRDRGTQLQRARAGEITAEMAFIAARE M AELVRDEVARGRAVIPANH+H
Sbjct 57 AGLPARPGRVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAVIPANHNH 116
Query 128 PESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR 187
PE EPMIIGKAFA KVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR
Sbjct 117 PEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR 176
Query 188 EWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY 247
EWILRNSPVPVGTVPIYQALEKVKGDPT LTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY
Sbjct 177 EWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY 236
Query 248 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGS 307
VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNF+ELC+IFARYDVTFSLGDGLRPGS
Sbjct 237 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSLGDGLRPGS 296
Query 308 IADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFY 367
IADANDAAQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEE CEEAPFY
Sbjct 297 IADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEEAPFY 356
Query 368 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 427
TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA
Sbjct 357 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 416
Query 428 AHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHF 487
AHA DLAKGHP AQ+RD+ALS ARFEFRWNDQFALSLDPDTARE+HDETLPAEPAKTAHF
Sbjct 417 AHAGDLAKGHPHAQQRDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAKTAHF 476
Query 488 CSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPITQ 547
CSMCGPKFCSMRITQDVR+YAA+HGL++E IE A MA+KSREFAEHGNRVYLP+ Q
Sbjct 477 CSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIE----AAMADKSREFAEHGNRVYLPLAQ 532
>gi|333989035|ref|YP_004521649.1| thiamine biosynthesis protein ThiC [Mycobacterium sp. JDM601]
gi|333485003|gb|AEF34395.1| thiamine biosynthesis protein ThiC [Mycobacterium sp. JDM601]
Length=547
Score = 976 bits (2523), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 478/544 (88%), Positives = 508/544 (94%), Gaps = 1/544 (0%)
Query 3 ITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDT 62
+ +EP VTTGPI S K YREIEAPG GA ++VPFRRV+L+ G+HFDLYDTSGPYTDTD
Sbjct 4 VVIEPQVTTGPIPYSEKIYREIEAPG-GAVMKVPFRRVNLTNGEHFDLYDTSGPYTDTDA 62
Query 63 VIDLTAGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIP 122
VIDL GLP RPGVVRDRGTQLQRA+AGEITAEMAFIAARE AELVRDEVARGRAVIP
Sbjct 63 VIDLHRGLPARPGVVRDRGTQLQRAQAGEITAEMAFIAAREGFPAELVRDEVARGRAVIP 122
Query 123 ANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKN 182
ANH+HPE EPMIIGKAF VK+NANIGNSAVTSSI EEVDKMVWATRWGAD IMDLSTGK+
Sbjct 123 ANHNHPELEPMIIGKAFKVKINANIGNSAVTSSIGEEVDKMVWATRWGADNIMDLSTGKD 182
Query 183 IHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAG 242
IHETREWILRNSPVPVGTVPIYQALEKV GDPT+L+WE+YRDTVIEQCEQGVDYMTVHAG
Sbjct 183 IHETREWILRNSPVPVGTVPIYQALEKVNGDPTKLSWELYRDTVIEQCEQGVDYMTVHAG 242
Query 243 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDG 302
VLLRYVPLTAKRVTGIVSRGGSIMA+WCL+ HRESFLYTNFEEL DI A YDVTFSLGDG
Sbjct 243 VLLRYVPLTAKRVTGIVSRGGSIMASWCLSRHRESFLYTNFEELADILASYDVTFSLGDG 302
Query 303 LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCE 362
LRPGSIADAND AQFAELRTLGELTKIAK+ GAQVMIEGPGH+PMHKIVENVRLEEE C+
Sbjct 303 LRPGSIADANDEAQFAELRTLGELTKIAKSRGAQVMIEGPGHVPMHKIVENVRLEEEWCD 362
Query 363 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 422
EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI
Sbjct 363 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 422
Query 423 AYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA 482
AYKIAAHAADLAKGHP AQ+RD+ALS ARFEFRW DQFALSLDPDTARE+HDETLPAEPA
Sbjct 423 AYKIAAHAADLAKGHPHAQDRDNALSKARFEFRWYDQFALSLDPDTAREYHDETLPAEPA 482
Query 483 KTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVY 542
K+AHFCSMCGPKFCSMRI+QDVR+YA EHGL+T+ DI+A +A GMAEKS EFAEHGNRVY
Sbjct 483 KSAHFCSMCGPKFCSMRISQDVRDYADEHGLQTQEDIDAAIAKGMAEKSAEFAEHGNRVY 542
Query 543 LPIT 546
LPI+
Sbjct 543 LPIS 546
>gi|169631274|ref|YP_001704923.1| thiamine biosynthesis protein ThiC [Mycobacterium abscessus ATCC
19977]
gi|238688919|sp|B1MIP8.1|THIC_MYCA9 RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|169243241|emb|CAM64269.1| Thiamine biosynthesis protein ThiC [Mycobacterium abscessus]
Length=546
Score = 937 bits (2422), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 463/538 (87%), Positives = 492/538 (92%), Gaps = 5/538 (0%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
+VTTGPI GS K Y+E+ P L+VP RRV+L+ G++ DLYDTSGPYTDT+ VIDL
Sbjct 13 TVTTGPIQGSEKIYQEL--PNG---LRVPQRRVNLTNGEYLDLYDTSGPYTDTNAVIDLH 67
Query 68 AGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHH 127
GLP R G+V DRGTQLQRARAGEITAEM FIA RE + AELVR EVA GRAVIPANH H
Sbjct 68 KGLPPRAGIVTDRGTQLQRARAGEITAEMEFIAVREGVPAELVRTEVAAGRAVIPANHKH 127
Query 128 PESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR 187
PESEPMIIGKAF VK+NANIGNSAVTSSIAEEV+KMVWA RWGAD IMDLSTGK+IH+TR
Sbjct 128 PESEPMIIGKAFGVKINANIGNSAVTSSIAEEVEKMVWAIRWGADNIMDLSTGKDIHQTR 187
Query 188 EWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY 247
EWILRNSPVPVGTVPIYQALEK GDP LTWE+YRDTVIEQ EQGVDYMTVHAGVLLRY
Sbjct 188 EWILRNSPVPVGTVPIYQALEKTNGDPAALTWELYRDTVIEQAEQGVDYMTVHAGVLLRY 247
Query 248 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGS 307
VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+FEELC+I ARYDVTFSLGDGLRPGS
Sbjct 248 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGDGLRPGS 307
Query 308 IADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFY 367
IADAND AQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENV+LEEELCEEAPFY
Sbjct 308 IADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVKLEEELCEEAPFY 367
Query 368 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 427
TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA
Sbjct 368 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 427
Query 428 AHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHF 487
AH+ADLAKGHPRAQ RD+ALS ARFEFRW DQF LSLDPDTAREFHDETLPAEPAKTAHF
Sbjct 428 AHSADLAKGHPRAQLRDNALSKARFEFRWEDQFNLSLDPDTAREFHDETLPAEPAKTAHF 487
Query 488 CSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
CSMCGPKFCSMRIT D+RE+AAE+GLET+ DI+A+LA GM EKS EFAEHGNRVYLPI
Sbjct 488 CSMCGPKFCSMRITADIREFAAENGLETQEDIDAMLARGMEEKSAEFAEHGNRVYLPI 545
>gi|118467543|ref|YP_885230.1| thiamine biosynthesis protein ThiC [Mycobacterium smegmatis str.
MC2 155]
gi|118168830|gb|ABK69726.1| thiamine biosynthesis protein ThiC [Mycobacterium smegmatis str.
MC2 155]
Length=524
Score = 932 bits (2408), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 460/538 (86%), Positives = 488/538 (91%), Gaps = 15/538 (2%)
Query 9 VTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTA 68
+TTGPI GS KAYRE+E PG L+VPFRRVHLS GDH DLYDTSGPYTDTD VIDL A
Sbjct 1 MTTGPITGSTKAYREVEHPGVDVPLRVPFRRVHLSDGDHLDLYDTSGPYTDTDAVIDLDA 60
Query 69 GLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHP 128
GL RPGVVRDRGTQLQRARAGEITAEMAFIA RE + AELVR EVARGRAVIPANH+HP
Sbjct 61 GLTPRPGVVRDRGTQLQRARAGEITAEMAFIAEREGVPAELVRSEVARGRAVIPANHNHP 120
Query 129 ESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETRE 188
ESEPMIIGKAF VKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG++IH TRE
Sbjct 121 ESEPMIIGKAFGVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGRDIHLTRE 180
Query 189 WILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYV 248
WILRNSPVPVGTVP+YQALEKV GDPT+L+W++YRDTVIEQCEQGVDYMTVHAGVLLR++
Sbjct 181 WILRNSPVPVGTVPMYQALEKVNGDPTKLSWDVYRDTVIEQCEQGVDYMTVHAGVLLRHI 240
Query 249 PLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSI 308
PLT RVTGIVSRGGSIMAAWCLAHH ESFLYTNFEELC+IFARYDVTFSLGDGLRPGSI
Sbjct 241 PLTVDRVTGIVSRGGSIMAAWCLAHHTESFLYTNFEELCEIFARYDVTFSLGDGLRPGSI 300
Query 309 ADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYT 368
ADANDAAQFAELRTLGELT IAK HG QVMIEGPGH+PMHKIVENVRLEEELC++APFYT
Sbjct 301 ADANDAAQFAELRTLGELTTIAKNHGVQVMIEGPGHVPMHKIVENVRLEEELCDDAPFYT 360
Query 369 LGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAA 428
LGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP+R+DVKDGVIAYKIAA
Sbjct 361 LGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPNRQDVKDGVIAYKIAA 420
Query 429 HAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFC 488
H+ADLAKGHPRAQ+RDDALS ARFEFRW+DQFALSLDPDTAREFHDETLPAEPAKTAHFC
Sbjct 421 HSADLAKGHPRAQQRDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPAEPAKTAHFC 480
Query 489 SMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPIT 546
SMCGPKFCSMRIT D+++ E M +KS EFAE GNRVYLP+T
Sbjct 481 SMCGPKFCSMRITADLKDSIRE---------------AMDQKSAEFAEQGNRVYLPLT 523
>gi|333918222|ref|YP_004491803.1| phosphomethylpyrimidine synthase [Amycolicicoccus subflavus DQS3-9A1]
gi|333480443|gb|AEF39003.1| Phosphomethylpyrimidine synthase [Amycolicicoccus subflavus DQS3-9A1]
Length=556
Score = 917 bits (2370), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 443/541 (82%), Positives = 478/541 (89%), Gaps = 9/541 (1%)
Query 12 GPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLP 71
GPI GS+K Y+ + S L P RRVHL+ GDH DLYDTSGPYTDT +IDL GLP
Sbjct 17 GPIEGSSKVYKPVPETKS---LTFPMRRVHLTNGDHLDLYDTSGPYTDTTALIDLENGLP 73
Query 72 H------RPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANH 125
+P V TQL ARAG IT EM +IAARE ++ E+VRDEVA GRAVI ANH
Sbjct 74 KQRDNWAKPAPVDGASTQLAWARAGIITDEMRYIAARESVAPEMVRDEVAAGRAVICANH 133
Query 126 HHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHE 185
HPE EPMIIGKAF VK+NANIGNSAV+S IAEEV+KMVWATRWGADTIMDLSTGK+IHE
Sbjct 134 KHPEIEPMIIGKAFGVKINANIGNSAVSSGIAEEVEKMVWATRWGADTIMDLSTGKDIHE 193
Query 186 TREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLL 245
TREWILRNSPVPVGTVPIYQALEKVKGDPT+LTWE+YRDTVIEQCEQGVDYMTVHAGVLL
Sbjct 194 TREWILRNSPVPVGTVPIYQALEKVKGDPTKLTWEMYRDTVIEQCEQGVDYMTVHAGVLL 253
Query 246 RYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRP 305
RY+PLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+F ELC+I YDVTFSLGDGLRP
Sbjct 254 RYIPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFRELCEILRTYDVTFSLGDGLRP 313
Query 306 GSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAP 365
GSIADAND AQFAELRTLGELTKIAK++G QVMIEGPGH+PMHKI ENVRLEEELCEEAP
Sbjct 314 GSIADANDEAQFAELRTLGELTKIAKSYGVQVMIEGPGHVPMHKIAENVRLEEELCEEAP 373
Query 366 FYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYK 425
FYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLP+R DVK GVIAYK
Sbjct 374 FYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLCYVTPKEHLGLPNRDDVKQGVIAYK 433
Query 426 IAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTA 485
IAAH+ADLAKGHPRAQERDDALS ARFEFRW DQF LSLDPDTARE+HDETLPAEPAKTA
Sbjct 434 IAAHSADLAKGHPRAQERDDALSKARFEFRWVDQFNLSLDPDTAREYHDETLPAEPAKTA 493
Query 486 HFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
HFCSMCGPKFCSMRI+QDVR+YA ++GL T+ DI+ V+A GMAEKS EFAEHGN+VYLP+
Sbjct 494 HFCSMCGPKFCSMRISQDVRDYAEQNGLATQEDIDRVIAEGMAEKSAEFAEHGNQVYLPL 553
Query 546 T 546
T
Sbjct 554 T 554
>gi|226361311|ref|YP_002779089.1| thiamine biosynthesis protein ThiC [Rhodococcus opacus B4]
gi|226239796|dbj|BAH50144.1| thiamine biosynthesis protein ThiC [Rhodococcus opacus B4]
Length=548
Score = 911 bits (2355), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 450/545 (83%), Positives = 480/545 (89%), Gaps = 11/545 (2%)
Query 3 ITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDT 62
I+ SVTTGPI GS K Y + SG ++VP RRV L+ G+H D+YDTSGPYTD D
Sbjct 5 ISTATSVTTGPIQGSTKQYLQ-----SGDDIRVPVRRVDLTNGEHLDVYDTSGPYTDADA 59
Query 63 VIDLTAGLPH-RPGVVRDRG-TQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAV 120
IDL AGLPH R + DR TQL ARAG +T EM + AARE +S E VR EVA GRAV
Sbjct 60 TIDLDAGLPHLRAPWIADRADTQLDAARAGIVTPEMRYCAAREGVSPETVRVEVAAGRAV 119
Query 121 IPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG 180
IPAN HPE EPMIIGKAFAVK+NANIGNSAVTSSIAEEV+KMVWATRWGADTIMDLSTG
Sbjct 120 IPANRCHPELEPMIIGKAFAVKINANIGNSAVTSSIAEEVEKMVWATRWGADTIMDLSTG 179
Query 181 KNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH 240
KNIHETREWILRNSPVPVGTVPIYQALEKV GDPT LTWEIYRDTVIEQCEQGVDYMTVH
Sbjct 180 KNIHETREWILRNSPVPVGTVPIYQALEKVNGDPTALTWEIYRDTVIEQCEQGVDYMTVH 239
Query 241 AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLG 300
AGVLLRY+PLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+F+ELC+I RYDVTFSLG
Sbjct 240 AGVLLRYIPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFDELCEILHRYDVTFSLG 299
Query 301 DGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEEL 360
DGLRPGSIADAND AQFAELRTLG+LTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEEL
Sbjct 300 DGLRPGSIADANDEAQFAELRTLGKLTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEL 359
Query 361 CEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDG 420
CEEAPFYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLP+R DVK G
Sbjct 360 CEEAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLCYVTPKEHLGLPNRDDVKIG 419
Query 421 VIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE 480
VI YKIAAHAADLAK HPRAQERDDALS ARFEFRW+DQFALSLDPDTAREFHDETLPAE
Sbjct 420 VITYKIAAHAADLAKQHPRAQERDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPAE 479
Query 481 PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNR 540
PAKTAHFCSMCGPKFCSMRI+ DVREYA +HGL++ IEA+ AGMAEKS EF + G R
Sbjct 480 PAKTAHFCSMCGPKFCSMRISADVREYAQKHGLDS---IEAI-EAGMAEKSSEFVDAGGR 535
Query 541 VYLPI 545
VYLP+
Sbjct 536 VYLPL 540
>gi|111019175|ref|YP_702147.1| thiamine biosynthesis protein ThiC [Rhodococcus jostii RHA1]
gi|110818705|gb|ABG93989.1| thiamine biosynthesis protein ThiC [Rhodococcus jostii RHA1]
Length=548
Score = 910 bits (2353), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 445/546 (82%), Positives = 475/546 (87%), Gaps = 11/546 (2%)
Query 2 TITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTD 61
++ SVTTGPI GS K Y S ++VP RRVHL+ G+H D+YDTSGPYTD D
Sbjct 4 NVSTATSVTTGPIEGSTKQYLL-----SADDVRVPVRRVHLTNGEHLDVYDTSGPYTDAD 58
Query 62 TVIDLTAGLPH--RPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRA 119
IDL AGLPH P + GTQL ARAG +T EM + AARE +S E VR EVA GRA
Sbjct 59 ATIDLEAGLPHLRAPWIADREGTQLDAARAGVVTPEMQYCAAREGVSPETVRTEVAAGRA 118
Query 120 VIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLST 179
VIPAN HPE EPMIIGKAFAVK+NANIGNSAVTSSIAEEV+KMVWATRWGADTIMDLST
Sbjct 119 VIPANRCHPELEPMIIGKAFAVKINANIGNSAVTSSIAEEVEKMVWATRWGADTIMDLST 178
Query 180 GKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTV 239
GKNIHETREWILRNSPVPVGTVPIYQALEKV GDPT LTWEIYRDTVIEQCEQGVDYMTV
Sbjct 179 GKNIHETREWILRNSPVPVGTVPIYQALEKVGGDPTALTWEIYRDTVIEQCEQGVDYMTV 238
Query 240 HAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSL 299
HAGVLLRY+PLTA+RVTGIVSRGGSIMAAWCLAHHRESFLY +F+ELC+I RYDVTFSL
Sbjct 239 HAGVLLRYIPLTARRVTGIVSRGGSIMAAWCLAHHRESFLYNHFDELCEILHRYDVTFSL 298
Query 300 GDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEE 359
GDGLRPGSIADAND AQFAELRTLGELT+IAK+HG QVMIEGPGH+PMHKIVENVRLEEE
Sbjct 299 GDGLRPGSIADANDEAQFAELRTLGELTRIAKSHGVQVMIEGPGHVPMHKIVENVRLEEE 358
Query 360 LCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKD 419
LCEEAPFYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLP+R DVK
Sbjct 359 LCEEAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLCYVTPKEHLGLPNRDDVKT 418
Query 420 GVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPA 479
GVI YKIAAHAADLAK HPRAQERDDALS ARFEFRW+DQFALSLDPDTAREFHDETLPA
Sbjct 419 GVITYKIAAHAADLAKQHPRAQERDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPA 478
Query 480 EPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGN 539
EPAKTAHFCSMCGPKFCSMRI+ DVREYA +HGL++ IE AGMAEKS EF + G
Sbjct 479 EPAKTAHFCSMCGPKFCSMRISADVREYAQQHGLDSVEAIE----AGMAEKSSEFVDAGG 534
Query 540 RVYLPI 545
RVYLP+
Sbjct 535 RVYLPV 540
>gi|120401740|ref|YP_951569.1| thiamine biosynthesis protein ThiC [Mycobacterium vanbaalenii
PYR-1]
gi|119954558|gb|ABM11563.1| hydroxymethylpyrimidine synthase [Mycobacterium vanbaalenii PYR-1]
Length=516
Score = 900 bits (2327), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 449/538 (84%), Positives = 476/538 (89%), Gaps = 30/538 (5%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
+VTTGPIAGS K YR VPFRRV+L+TG+H DLYDTSGPYTD VIDL
Sbjct 6 NVTTGPIAGSTKVYRN----------GVPFRRVNLTTGEHLDLYDTSGPYTDAGAVIDLE 55
Query 68 AGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHH 127
AGLPHR V R+RGTQLQRARAGEITAEMAFIA RE +S ELVRDEVARGRAVIPANH+H
Sbjct 56 AGLPHRR-VTRNRGTQLQRARAGEITAEMAFIAEREGVSPELVRDEVARGRAVIPANHNH 114
Query 128 PESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR 187
PE+EPMIIGKAFAVK+NANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTG++IH+TR
Sbjct 115 PEAEPMIIGKAFAVKINANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGRDIHQTR 174
Query 188 EWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY 247
EWILRNSPVPVGTVP+YQALEKV GDP +LTWE+YRDTVIEQCEQGVDYMTVHAGVLLR+
Sbjct 175 EWILRNSPVPVGTVPMYQALEKVGGDPVKLTWEVYRDTVIEQCEQGVDYMTVHAGVLLRH 234
Query 248 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGS 307
+PLT RVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELC I ARYDVTFSLGDGLRPGS
Sbjct 235 IPLTVDRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCGILARYDVTFSLGDGLRPGS 294
Query 308 IADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFY 367
IADANDAAQFAELRTLGELT +AK+HG QVMIEGPGH+PMHKIVENVRLEEELCEEAPFY
Sbjct 295 IADANDAAQFAELRTLGELTGMAKSHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFY 354
Query 368 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 427
TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP+RKDVKDGVIAYKIA
Sbjct 355 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPNRKDVKDGVIAYKIA 414
Query 428 AHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHF 487
AHAADLAKGHP AQ RDDALS ARFEFRW DQF LSLDPDTAREFHDETLPA PAKTAHF
Sbjct 415 AHAADLAKGHPGAQARDDALSKARFEFRWEDQFNLSLDPDTAREFHDETLPATPAKTAHF 474
Query 488 CSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
CSMCGPKFCSMRI+ +V+E M EKSREFA+ GN+VYLP+
Sbjct 475 CSMCGPKFCSMRISHEVQE-------------------AMKEKSREFADQGNKVYLPV 513
>gi|326383427|ref|ZP_08205114.1| thiamine biosynthesis protein ThiC [Gordonia neofelifaecis NRRL
B-59395]
gi|326197833|gb|EGD55020.1| thiamine biosynthesis protein ThiC [Gordonia neofelifaecis NRRL
B-59395]
Length=560
Score = 898 bits (2321), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 441/549 (81%), Positives = 476/549 (87%), Gaps = 16/549 (2%)
Query 9 VTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTA 68
VT GPI GS K Y +++ + VP RRVHL+ G+H DLYDTSGPYTD+ +IDL A
Sbjct 15 VTCGPIEGSTKHYLDVDG------MAVPRRRVHLTNGEHLDLYDTSGPYTDSSAIIDLEA 68
Query 69 GLPH------RPGVVRDRG----TQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGR 118
GL P V+ G TQL AR G IT EMAFIAARE +S E VR+E+A GR
Sbjct 69 GLAKTRDAWTHPAPVQVAGHAAATQLAWAREGIITPEMAFIAAREGVSPESVREEIAAGR 128
Query 119 AVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLS 178
AVIPANH HPE EPMIIGKAFAVKVNANIGNSAVTSSIAEEV+KMVWATRWGADTIMDLS
Sbjct 129 AVIPANHRHPECEPMIIGKAFAVKVNANIGNSAVTSSIAEEVEKMVWATRWGADTIMDLS 188
Query 179 TGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMT 238
TGK+IH TREWI+RNSPVPVGTVPIYQALEKV GDPT+LTWEIYRDTVIEQ EQGVDYMT
Sbjct 189 TGKDIHLTREWIMRNSPVPVGTVPIYQALEKVNGDPTKLTWEIYRDTVIEQAEQGVDYMT 248
Query 239 VHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFS 298
VHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLY +F ELC+IFA+YD+TFS
Sbjct 249 VHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYEHFGELCEIFAQYDITFS 308
Query 299 LGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEE 358
LGDGLRPGSIADAND AQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKI ENVRLEE
Sbjct 309 LGDGLRPGSIADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIAENVRLEE 368
Query 359 ELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVK 418
ELCEEAPFYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLP+R DVK
Sbjct 369 ELCEEAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLCYVTPKEHLGLPNRDDVK 428
Query 419 DGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLP 478
GVI YKIAAH+ADLAKGHPRAQERDDALS ARFEFRW DQF L+LDPDTARE+HDET+P
Sbjct 429 VGVITYKIAAHSADLAKGHPRAQERDDALSKARFEFRWTDQFNLALDPDTAREYHDETMP 488
Query 479 AEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHG 538
AEPAKTAHFCSMCGPKFCSMRI+ DVR YA ++GL T+ DI+A LA MA KS EFA G
Sbjct 489 AEPAKTAHFCSMCGPKFCSMRISADVRTYAEQNGLVTQEDIDARLAQDMAAKSAEFAASG 548
Query 539 NRVYLPITQ 547
N+VYLPIT+
Sbjct 549 NQVYLPITE 557
>gi|343924277|ref|ZP_08763836.1| phosphomethylpyrimidine synthase [Gordonia alkanivorans NBRC
16433]
gi|343765807|dbj|GAA10762.1| phosphomethylpyrimidine synthase [Gordonia alkanivorans NBRC
16433]
Length=563
Score = 892 bits (2306), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 438/543 (81%), Positives = 470/543 (87%), Gaps = 12/543 (2%)
Query 9 VTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTA 68
+TTGPI GS+K Y ++ L+VP RR+HL+ G+H D+YDTSGPYTD D VID+
Sbjct 19 LTTGPIEGSSKHYLSVD------HLRVPQRRIHLTNGEHLDVYDTSGPYTDPDAVIDVER 72
Query 69 GLP------HRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIP 122
GLP HRP V TQL ARAG +T EM FIAARE + +LVR EVA GRAVIP
Sbjct 73 GLPPTRDAWHRPEPVDGASTQLAWARAGIVTDEMRFIAAREGVDPDLVRSEVAIGRAVIP 132
Query 123 ANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKN 182
ANH HPESEPMIIGK FAVK+NANIGNSAV SSIA+EV+KMVWATRWGADTIMDLSTG +
Sbjct 133 ANHRHPESEPMIIGKRFAVKINANIGNSAVRSSIADEVEKMVWATRWGADTIMDLSTGAD 192
Query 183 IHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAG 242
IH TREWILRNSPVPVGTVPIYQALEKV GDP LTWEIYRDTVIEQ EQGVDYMTVHAG
Sbjct 193 IHTTREWILRNSPVPVGTVPIYQALEKVNGDPVALTWEIYRDTVIEQAEQGVDYMTVHAG 252
Query 243 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDG 302
VLLRYVPLTA+RVTGIVSRGGSIMAAWCLAHH ESFLYT+F+ELC+IF RYD+TFSLGDG
Sbjct 253 VLLRYVPLTARRVTGIVSRGGSIMAAWCLAHHEESFLYTHFDELCEIFRRYDITFSLGDG 312
Query 303 LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCE 362
LRPGSIADAND AQFAELRTLGELT IAK+HG QVMIEGPGHIPMHKIVENVRLEEELCE
Sbjct 313 LRPGSIADANDEAQFAELRTLGELTSIAKSHGVQVMIEGPGHIPMHKIVENVRLEEELCE 372
Query 363 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 422
EAPFYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLPDR DVK GVI
Sbjct 373 EAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLCYVTPKEHLGLPDRDDVKVGVI 432
Query 423 AYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA 482
YKIAAH+ADLAKGHPRAQERDDALS ARFEFRW DQF L+LDPDTARE+HDETLPAEPA
Sbjct 433 TYKIAAHSADLAKGHPRAQERDDALSKARFEFRWVDQFNLALDPDTAREYHDETLPAEPA 492
Query 483 KTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVY 542
KTAHFCSMCGPKFCSMRI+ DVR YA E+ L T DI+ +A GMA KS EFAE GNRVY
Sbjct 493 KTAHFCSMCGPKFCSMRISADVRAYAEENNLVTAEDIDRKIAEGMAAKSAEFAEAGNRVY 552
Query 543 LPI 545
LP+
Sbjct 553 LPL 555
>gi|262200661|ref|YP_003271869.1| thiamine biosynthesis protein ThiC [Gordonia bronchialis DSM
43247]
gi|262084008|gb|ACY19976.1| thiamine biosynthesis protein ThiC [Gordonia bronchialis DSM
43247]
Length=568
Score = 892 bits (2306), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 434/543 (80%), Positives = 469/543 (87%), Gaps = 12/543 (2%)
Query 9 VTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTA 68
+TTGPI GS K Y E+E L++P RR+HL+ G+H D+YDTSGPYTD ID+
Sbjct 23 LTTGPIEGSRKHYLELEH------LRIPQRRIHLTNGEHLDVYDTSGPYTDDAADIDVER 76
Query 69 GLP------HRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIP 122
GLP RP V TQL ARAG +T EM F+AARE++ ELVR EVA GRAVIP
Sbjct 77 GLPRMRDSWQRPEPVDGASTQLAWARAGVVTDEMRFVAARENVDVELVRSEVAAGRAVIP 136
Query 123 ANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKN 182
NH HPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEV+KMVWATRWGADTIMDLSTGK+
Sbjct 137 VNHRHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVEKMVWATRWGADTIMDLSTGKD 196
Query 183 IHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAG 242
IH TREWI+RNSPVPVGTVPIYQALEKV GDPT LTWEIYRDTVIEQ EQGVDYMTVHAG
Sbjct 197 IHMTREWIMRNSPVPVGTVPIYQALEKVNGDPTRLTWEIYRDTVIEQAEQGVDYMTVHAG 256
Query 243 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDG 302
VLLRYVPLTA+RVTGIVSRGGSIMAAWCLAHH+ESFLYTNF+ELC+IF RYD+TFSLGDG
Sbjct 257 VLLRYVPLTARRVTGIVSRGGSIMAAWCLAHHQESFLYTNFDELCEIFRRYDITFSLGDG 316
Query 303 LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCE 362
LRPGSIADAND AQFAELRTLGELT IAK++G QVMIEGPGH+PMHKI ENVRLEEE CE
Sbjct 317 LRPGSIADANDEAQFAELRTLGELTTIAKSYGVQVMIEGPGHVPMHKIAENVRLEEEYCE 376
Query 363 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 422
EAPFYTLGPLATDIAPAYDHITSAIGAA+IAQAGTAMLCYVTPKEHLGLP+R DVK GVI
Sbjct 377 EAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLCYVTPKEHLGLPNRDDVKVGVI 436
Query 423 AYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA 482
YKIAAH+ADL+KGHPRAQERDDALS ARFEFRW DQF L+LDPDTARE+HDETLPAEPA
Sbjct 437 TYKIAAHSADLSKGHPRAQERDDALSKARFEFRWTDQFNLALDPDTAREYHDETLPAEPA 496
Query 483 KTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVY 542
KTAHFCSMCGPKFCSMRI+ DVR YA E+ L T DI+ +A MA KS EFAE GNRVY
Sbjct 497 KTAHFCSMCGPKFCSMRISADVRAYAEENNLVTAEDIDRKIAEEMAAKSAEFAESGNRVY 556
Query 543 LPI 545
LP+
Sbjct 557 LPL 559
>gi|145221349|ref|YP_001132027.1| thiamine biosynthesis protein ThiC [Mycobacterium gilvum PYR-GCK]
gi|145213835|gb|ABP43239.1| hydroxymethylpyrimidine synthase [Mycobacterium gilvum PYR-GCK]
Length=528
Score = 888 bits (2294), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 451/538 (84%), Positives = 475/538 (89%), Gaps = 20/538 (3%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
SVTTGPI GS+K YRE+ G +VPFRRVHL+TGDH DLYDTSGPYTD VIDL
Sbjct 9 SVTTGPITGSSKVYRELSDGG-----RVPFRRVHLTTGDHLDLYDTSGPYTDDTAVIDLA 63
Query 68 AGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHH 127
AGLP R GVVRD GTQL RAR GEITAEMAFIA RE + ELVRDEVARGRAVIPANH+H
Sbjct 64 AGLPERSGVVRDSGTQLMRARKGEITAEMAFIAEREGLPVELVRDEVARGRAVIPANHNH 123
Query 128 PESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR 187
PESEPMIIGKAFAVKVNANIGNSAVTSS+AEEVDKMVWATRWGADTIMDLSTG +IH TR
Sbjct 124 PESEPMIIGKAFAVKVNANIGNSAVTSSVAEEVDKMVWATRWGADTIMDLSTGADIHLTR 183
Query 188 EWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY 247
EWILRNSPVPVGTVPIYQALEKV GDPT+LTW++YRDTVIEQCEQGVDYMTVHAGVLLRY
Sbjct 184 EWILRNSPVPVGTVPIYQALEKVDGDPTQLTWKVYRDTVIEQCEQGVDYMTVHAGVLLRY 243
Query 248 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGS 307
+PLT RVTGIVSRGGSIMAAW LAHH ESFLYT+F ELC+I ARYDVTFSLGDGLRPGS
Sbjct 244 IPLTVNRVTGIVSRGGSIMAAWMLAHHTESFLYTHFAELCEILARYDVTFSLGDGLRPGS 303
Query 308 IADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFY 367
IADAND AQFAELRTLGELTKIAKAHG QVMIEGPGH+PMHKIVENVRLEEELCEEAPFY
Sbjct 304 IADANDEAQFAELRTLGELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFY 363
Query 368 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 427
TLGPL TDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDR DVK GVI YKIA
Sbjct 364 TLGPLTTDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRSDVKTGVITYKIA 423
Query 428 AHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHF 487
AHAADLAK HPRAQERDDALSTARFEFRWNDQFALSLDPD+A FHDETLPA PAKTAHF
Sbjct 424 AHAADLAKAHPRAQERDDALSTARFEFRWNDQFALSLDPDSACGFHDETLPAVPAKTAHF 483
Query 488 CSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
CSMCGPKFCSMRI++DVR+ GM +KS+EFA+HGNR+YLP+
Sbjct 484 CSMCGPKFCSMRISRDVRD---------------AYEKGMTDKSQEFAKHGNRIYLPL 526
>gi|315441767|ref|YP_004074646.1| hydroxymethylpyrimidine synthase [Mycobacterium sp. Spyr1]
gi|315260070|gb|ADT96811.1| hydroxymethylpyrimidine synthase [Mycobacterium sp. Spyr1]
Length=525
Score = 886 bits (2290), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 451/538 (84%), Positives = 475/538 (89%), Gaps = 20/538 (3%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
SVTTGPI GS+K YRE+ G +VPFRRVHL+TGDH DLYDTSGPYTD VIDL
Sbjct 6 SVTTGPITGSSKVYRELSDGG-----RVPFRRVHLTTGDHLDLYDTSGPYTDDTAVIDLA 60
Query 68 AGLPHRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHH 127
AGLP R GVVRD GTQL RAR GEITAEMAFIA RE + ELVRDEVARGRAVIPANH+H
Sbjct 61 AGLPERSGVVRDSGTQLMRARKGEITAEMAFIAEREGLPVELVRDEVARGRAVIPANHNH 120
Query 128 PESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETR 187
PESEPMIIGKAFAVKVNANIGNSAVTSS+AEEVDKMVWATRWGADTIMDLSTG +IH TR
Sbjct 121 PESEPMIIGKAFAVKVNANIGNSAVTSSVAEEVDKMVWATRWGADTIMDLSTGADIHLTR 180
Query 188 EWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRY 247
EWILRNSPVPVGTVPIYQALEKV GDPT+LTW++YRDTVIEQCEQGVDYMTVHAGVLLRY
Sbjct 181 EWILRNSPVPVGTVPIYQALEKVDGDPTQLTWKVYRDTVIEQCEQGVDYMTVHAGVLLRY 240
Query 248 VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGS 307
+PLT RVTGIVSRGGSIMAAW LAHH ESFLYT+F ELC+I ARYDVTFSLGDGLRPGS
Sbjct 241 IPLTVNRVTGIVSRGGSIMAAWMLAHHTESFLYTHFAELCEILARYDVTFSLGDGLRPGS 300
Query 308 IADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFY 367
IADAND AQFAELRTLGELTKIAKAHG QVMIEGPGH+PMHKIVENVRLEEELCEEAPFY
Sbjct 301 IADANDEAQFAELRTLGELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFY 360
Query 368 TLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIA 427
TLGPL TDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDR DVK GVI YKIA
Sbjct 361 TLGPLTTDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRSDVKTGVITYKIA 420
Query 428 AHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHF 487
AHAADLAK HPRAQERDDALSTARFEFRWNDQFALSLDPD+A FHDETLPA PAKTAHF
Sbjct 421 AHAADLAKAHPRAQERDDALSTARFEFRWNDQFALSLDPDSACGFHDETLPAVPAKTAHF 480
Query 488 CSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
CSMCGPKFCSMRI++DVR+ GM +KS+EFA+HGNR+YLP+
Sbjct 481 CSMCGPKFCSMRISRDVRD---------------AYEKGMTDKSQEFAKHGNRIYLPL 523
>gi|54027290|ref|YP_121532.1| thiamine biosynthesis protein ThiC [Nocardia farcinica IFM 10152]
gi|81602361|sp|Q5YNS3.1|THIC_NOCFA RecName: Full=Phosphomethylpyrimidine synthase; AltName: Full=Hydroxymethylpyrimidine
phosphate synthase; Short=HMP-P synthase;
Short=HMP-phosphate synthase; Short=HMPP synthase; AltName:
Full=Thiamine biosynthesis protein thiC
gi|54018798|dbj|BAD60168.1| putative thiamine biosynthesis protein [Nocardia farcinica IFM
10152]
Length=547
Score = 873 bits (2256), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 441/544 (82%), Positives = 472/544 (87%), Gaps = 17/544 (3%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
+VTTGPI GS K YRE++ L++P RR++L+ G+ FD+YDTSGPYTD + IDL
Sbjct 13 TVTTGPIEGSVKHYREVDG------LRIPVRRINLTNGETFDVYDTSGPYTDENATIDLE 66
Query 68 AGLPH------RPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVI 121
AGLP +P V R TQL ARAG +T EM FIAARE + ELVR EVA GRAVI
Sbjct 67 AGLPKLRDSWDKPTVAGPR-TQLAWARAGIVTPEMRFIAAREGVEPELVRAEVAAGRAVI 125
Query 122 PANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGK 181
PANH+HPE EP IIGK F VK+NANIGNSAV+SSIAEEV+KMVWATRWGADTIMDLSTGK
Sbjct 126 PANHNHPELEPTIIGKKFLVKINANIGNSAVSSSIAEEVEKMVWATRWGADTIMDLSTGK 185
Query 182 NIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHA 241
NIHETREWILRNSPVPVGTVPIYQALEKV GDP LTWEIYRDTVIEQ EQGVDYMTVHA
Sbjct 186 NIHETREWILRNSPVPVGTVPIYQALEKVNGDPAALTWEIYRDTVIEQAEQGVDYMTVHA 245
Query 242 GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGD 301
GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+FEELC+I ARYDVTFSLGD
Sbjct 246 GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILARYDVTFSLGD 305
Query 302 GLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELC 361
GLRPGS+ADAND AQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEELC
Sbjct 306 GLRPGSVADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELC 365
Query 362 EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGV 421
EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP+R DVK GV
Sbjct 366 EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPNRDDVKTGV 425
Query 422 IAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEP 481
I YKIAAHAADLAKGHP AQ+RDDALS ARFEFRW DQFALSLDPDTARE+HDET+PAEP
Sbjct 426 ITYKIAAHAADLAKGHPHAQQRDDALSKARFEFRWRDQFALSLDPDTAREYHDETMPAEP 485
Query 482 AKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRV 541
AKTAHFCSMCGPKFCSMRI+ DVREYA + L A IE AGMA KS EFAE G +V
Sbjct 486 AKTAHFCSMCGPKFCSMRISADVREYAEANNLTDVAAIE----AGMAAKSAEFAESGGKV 541
Query 542 YLPI 545
YLP+
Sbjct 542 YLPV 545
>gi|284028926|ref|YP_003378857.1| thiamine biosynthesis protein ThiC [Kribbella flavida DSM 17836]
gi|283808219|gb|ADB30058.1| thiamine biosynthesis protein ThiC [Kribbella flavida DSM 17836]
Length=545
Score = 871 bits (2250), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 427/544 (79%), Positives = 461/544 (85%), Gaps = 15/544 (2%)
Query 5 VEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVI 64
V PSVTTGPI+GS K YR L+VP RRV+L+ G+HFDLYDTSGPYTD I
Sbjct 12 VRPSVTTGPISGSQKIYR--------GDLRVPARRVNLTNGEHFDLYDTSGPYTDAAAAI 63
Query 65 DLTAGLPH-RPGVVRDRG--TQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVI 121
D+ GLP R V R TQL ARAG IT EM +IA RE + E VRDEVARGRAVI
Sbjct 64 DVQTGLPAIRRDWVAGRAPLTQLAHARAGTITEEMRYIAVREGVEPEFVRDEVARGRAVI 123
Query 122 PANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGK 181
PANH HPESEPMIIGK F VKVNANIGNSAVTSSI +EV+K+VWATRWGADT+MDLSTGK
Sbjct 124 PANHRHPESEPMIIGKKFLVKVNANIGNSAVTSSIEQEVEKLVWATRWGADTVMDLSTGK 183
Query 182 NIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHA 241
NIHETREWILRNSPVP+GTVP+YQALEKVKGDP EL+WE+YRDTVIEQCEQGVDYMTVHA
Sbjct 184 NIHETREWILRNSPVPIGTVPLYQALEKVKGDPAELSWEVYRDTVIEQCEQGVDYMTVHA 243
Query 242 GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGD 301
GVLLRYVPLTA+RVTGIVSRGGSIMAAWCLAHH+ESFLYT+F ELC+I YDVTFSLGD
Sbjct 244 GVLLRYVPLTARRVTGIVSRGGSIMAAWCLAHHQESFLYTHFAELCEILREYDVTFSLGD 303
Query 302 GLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELC 361
GLRPGSIADANDAAQFAELRTLGELTKIA H QVMIEGPGH+PMHKI ENVRLEEELC
Sbjct 304 GLRPGSIADANDAAQFAELRTLGELTKIAWQHDVQVMIEGPGHVPMHKIAENVRLEEELC 363
Query 362 EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGV 421
EAPFYTLGPLATD+APAYDHITSAIGAA I GTAMLCYVTPKEHLGLPDR DVK GV
Sbjct 364 GEAPFYTLGPLATDVAPAYDHITSAIGAAQIGWLGTAMLCYVTPKEHLGLPDRDDVKTGV 423
Query 422 IAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEP 481
I YKIAAHAADLAKGHP AQ+ DDALSTARFEFRW DQF LSLDPDTAR +HDETLPAEP
Sbjct 424 ITYKIAAHAADLAKGHPGAQDWDDALSTARFEFRWEDQFNLSLDPDTARSYHDETLPAEP 483
Query 482 AKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRV 541
AKTAHFCSMCGPKFCSMRIT D+REYA +HGL + IE AG+AE S F ++ +++
Sbjct 484 AKTAHFCSMCGPKFCSMRITADIREYAEQHGLTSTEAIE----AGLAEMSETFKDNDSKL 539
Query 542 YLPI 545
YLP+
Sbjct 540 YLPV 543
>gi|257057415|ref|YP_003135247.1| thiamine biosynthesis protein ThiC [Saccharomonospora viridis
DSM 43017]
gi|256587287|gb|ACU98420.1| hydroxymethylpyrimidine synthase [Saccharomonospora viridis DSM
43017]
Length=548
Score = 870 bits (2248), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 430/547 (79%), Positives = 461/547 (85%), Gaps = 12/547 (2%)
Query 2 TITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTD 61
T V+P+VTTGPI GS K Y E E+ L+VP RR+ LS G+HFD+YDTSGPYTD
Sbjct 8 TSDVKPTVTTGPITGSRKVYLETES-----GLRVPVRRIELSNGEHFDVYDTSGPYTDPQ 62
Query 62 TVIDLTAGLP--HRPGVV-RDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGR 118
ID+ GLP P + R+ TQL A+AG IT EM FIAARE + E VR EVARGR
Sbjct 63 ATIDVHKGLPKLRAPWIEGREHKTQLGWAKAGVITPEMEFIAARERVDPEFVRSEVARGR 122
Query 119 AVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLS 178
AVIPAN +HPESEPMIIGK F VKVNAN+GNSAV SS+ EEVDKMVWATRWGADT+MDLS
Sbjct 123 AVIPANRNHPESEPMIIGKNFLVKVNANMGNSAVWSSVEEEVDKMVWATRWGADTVMDLS 182
Query 179 TGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMT 238
TGK IHETREWILRNSPVPVGTVPIYQALEKV GDPT+L+WE+YRDTVIEQCEQGVDYMT
Sbjct 183 TGKRIHETREWILRNSPVPVGTVPIYQALEKVGGDPTKLSWEVYRDTVIEQCEQGVDYMT 242
Query 239 VHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFS 298
VHAGVLLRYVPLTA RVTGIVSRGGSIMAAWCLAHH+ESFLYT+FEELCDI YDVTFS
Sbjct 243 VHAGVLLRYVPLTANRVTGIVSRGGSIMAAWCLAHHKESFLYTHFEELCDILREYDVTFS 302
Query 299 LGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEE 358
LGDGLRPGSIADAND AQFAEL TLGELT+IA+ QVMIEGPGH+PMHKI ENV +E
Sbjct 303 LGDGLRPGSIADANDRAQFAELETLGELTRIARERDVQVMIEGPGHVPMHKIKENVERQE 362
Query 359 ELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVK 418
LC+EAPFYTLGPLATDIAPAYDHITSAIGAA IA GTAMLCYVTPKEHLGLP+R DVK
Sbjct 363 RLCDEAPFYTLGPLATDIAPAYDHITSAIGAAQIAWYGTAMLCYVTPKEHLGLPNRDDVK 422
Query 419 DGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLP 478
GVI+YKIAAHAADLAKGHP AQE DDALS ARFEFRWNDQF LSLDPDTAR FHDETLP
Sbjct 423 TGVISYKIAAHAADLAKGHPYAQEWDDALSKARFEFRWNDQFNLSLDPDTARSFHDETLP 482
Query 479 AEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHG 538
AEPAKTAHFCSMCGPKFCSMRITQDVR YA EHGL + IE AGM EKSREF E G
Sbjct 483 AEPAKTAHFCSMCGPKFCSMRITQDVRAYAEEHGLTSVEAIE----AGMREKSREFTEKG 538
Query 539 NRVYLPI 545
+VYLP+
Sbjct 539 GQVYLPV 545
>gi|297562633|ref|YP_003681607.1| thiamine biosynthesis protein ThiC [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
gi|296847081|gb|ADH69101.1| thiamine biosynthesis protein ThiC [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
Length=564
Score = 865 bits (2234), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 427/552 (78%), Positives = 458/552 (83%), Gaps = 12/552 (2%)
Query 1 MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDT 60
++ T + VTTGPI GS K YRE+ P G TL+VP RRV LS G HFDLYDTSGPYTD
Sbjct 9 VSSTADHRVTTGPIMGSRKVYREVATP-EGHTLRVPQRRVELSNGSHFDLYDTSGPYTDD 67
Query 61 DTVIDLTAGLP-------HRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDE 113
ID+ GL H P TQL A+AG IT EM F+AARE + E VR E
Sbjct 68 TAHIDVHRGLAPTRGEWAHAPAPSGGATTQLAHAKAGTITPEMRFVAAREGVDPEFVRQE 127
Query 114 VARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADT 173
VA GRAVIPAN HPESEPMIIGK F VK+NANIGNSAVTSS+ EEV+KMVWATRWGADT
Sbjct 128 VAVGRAVIPANRCHPESEPMIIGKNFLVKINANIGNSAVTSSVPEEVEKMVWATRWGADT 187
Query 174 IMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQG 233
+MDLSTGK IHETRE ILRNSPVP+GTVPIYQALEKV GDP L+WE+YRDTVIEQCEQG
Sbjct 188 VMDLSTGKRIHETRERILRNSPVPIGTVPIYQALEKVNGDPAALSWEVYRDTVIEQCEQG 247
Query 234 VDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARY 293
VDYMTVHAGVLLRYVPLTA+RVTGIVSRGGSIMAAWCLAHHRESFLYT++EELC+I Y
Sbjct 248 VDYMTVHAGVLLRYVPLTARRVTGIVSRGGSIMAAWCLAHHRESFLYTHYEELCEILREY 307
Query 294 DVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVEN 353
DVTFSLGDGLRPGSIADAND AQFAELRTLGELT IA+AH QVMIEGPGH+PMHKI EN
Sbjct 308 DVTFSLGDGLRPGSIADANDEAQFAELRTLGELTHIARAHDVQVMIEGPGHVPMHKIAEN 367
Query 354 VRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPD 413
VRLEEELC EAPFYTLGPLATD+AP YDHITSAIGAA I GTAMLCYVTPKEHLGLPD
Sbjct 368 VRLEEELCGEAPFYTLGPLATDVAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLGLPD 427
Query 414 RKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFH 473
R DVK GVI YK+AAHAADLAKGHPRAQE DD LS ARFEFRW DQF L+LDP+TA+ FH
Sbjct 428 RDDVKTGVITYKLAAHAADLAKGHPRAQEWDDELSKARFEFRWQDQFHLALDPETAQSFH 487
Query 474 DETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSRE 533
D+TLPAEPAKTAHFCSMCGPKFCSM+ITQDVR YA EHGLET A IE GMA+KS E
Sbjct 488 DQTLPAEPAKTAHFCSMCGPKFCSMKITQDVRRYAEEHGLETVAAIE----KGMADKSAE 543
Query 534 FAEHGNRVYLPI 545
FAE G RVYLP+
Sbjct 544 FAEQGKRVYLPL 555
>gi|296141411|ref|YP_003648654.1| thiamine biosynthesis protein ThiC [Tsukamurella paurometabola
DSM 20162]
gi|296029545|gb|ADG80315.1| thiamine biosynthesis protein ThiC [Tsukamurella paurometabola
DSM 20162]
Length=566
Score = 863 bits (2230), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 439/553 (80%), Positives = 466/553 (85%), Gaps = 17/553 (3%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTD---TDTVI 64
+VT GPI GS K YR I GS TL+VPFRR+ L+ GDH D+YDTSGPYT D +
Sbjct 11 TVTVGPIEGSEKGYRAIA--GSNGTLRVPFRRISLTNGDHHDVYDTSGPYTQYASEDQLH 68
Query 65 DLTAGLPH--------RPGVVRDRG----TQLQRARAGEITAEMAFIAAREDMSAELVRD 112
DL AGLP P + G TQL ARAG IT E+ F+AARE E VR
Sbjct 69 DLQAGLPKTRDEWAKPEPVATENGGAGARTQLAWARAGVITDEIRFVAAREGFDPEFVRA 128
Query 113 EVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGAD 172
EVA GRAVIPANH HPE EP IIGKAFAVK+NANIGNSAVTSSI EEV+KMVWATRWG D
Sbjct 129 EVAAGRAVIPANHKHPELEPAIIGKAFAVKINANIGNSAVTSSIGEEVEKMVWATRWGGD 188
Query 173 TIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQ 232
TIMDLSTGK+IHETREWI+RNSPVPVGTVPIYQALEKVKGDPT+LTWEIYRDTVIEQCEQ
Sbjct 189 TIMDLSTGKDIHETREWIMRNSPVPVGTVPIYQALEKVKGDPTKLTWEIYRDTVIEQCEQ 248
Query 233 GVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFAR 292
GVDYMTVHAGVLLRYVPL A RVTGIVSRGGSIMAAWCLAHH ESFLYT+F ELC+I
Sbjct 249 GVDYMTVHAGVLLRYVPLAANRVTGIVSRGGSIMAAWCLAHHEESFLYTHFGELCEILRE 308
Query 293 YDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVE 352
YDVTFSLGDGLRPGSIADAND AQFAELRTLGELTKIAK++G QVMIEGPGH+PMHKIVE
Sbjct 309 YDVTFSLGDGLRPGSIADANDEAQFAELRTLGELTKIAKSYGVQVMIEGPGHVPMHKIVE 368
Query 353 NVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP 412
NVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP
Sbjct 369 NVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP 428
Query 413 DRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREF 472
+R DVK GVI YKIAAH+ADLAKGHP AQ RDD LS ARFEFRW DQF LSLDPDTAREF
Sbjct 429 NRDDVKTGVITYKIAAHSADLAKGHPGAQSRDDELSKARFEFRWVDQFNLSLDPDTAREF 488
Query 473 HDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSR 532
HDETLPAEPAKTAHFCSMCGPKFCSMRI+ DVR YA EH L T+ DI A LAA MAEKS+
Sbjct 489 HDETLPAEPAKTAHFCSMCGPKFCSMRISADVRAYAQEHNLVTQEDIAAKLAADMAEKSK 548
Query 533 EFAEHGNRVYLPI 545
EF + G RVY+P+
Sbjct 549 EFTDAGGRVYIPL 561
>gi|302530617|ref|ZP_07282959.1| ThiC protein [Streptomyces sp. AA4]
gi|302439512|gb|EFL11328.1| ThiC protein [Streptomyces sp. AA4]
Length=547
Score = 860 bits (2221), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 424/546 (78%), Positives = 456/546 (84%), Gaps = 12/546 (2%)
Query 5 VEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVI 64
+ PSVTTGPI GS K Y E+ L+VP RR+ LS G+HFD+YDTSGPYTD D I
Sbjct 10 IAPSVTTGPITGSRKVYHRTES-----GLRVPARRIDLSNGEHFDVYDTSGPYTDPDANI 64
Query 65 DLTAGL-PHRPGVV--RDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVI 121
D+ GL P R G R+ TQL A+AG IT EM FIAARE + E VRDEVARGRAVI
Sbjct 65 DVHNGLHPLRSGWADGREHNTQLGWAKAGVITREMEFIAARERCTPEFVRDEVARGRAVI 124
Query 122 PANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGK 181
P N HPE+EPMIIGK F VK+NAN+GNSAV SS+ EEVDKMVWATRWGADTIMDLSTGK
Sbjct 125 PVNRKHPETEPMIIGKNFLVKINANMGNSAVWSSVEEEVDKMVWATRWGADTIMDLSTGK 184
Query 182 NIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHA 241
IHETREWI+RNSPVPVGTVPIYQALEKV G+P +LTWEIYRDTVIEQCEQGVDYMTVHA
Sbjct 185 RIHETREWIVRNSPVPVGTVPIYQALEKVNGEPEKLTWEIYRDTVIEQCEQGVDYMTVHA 244
Query 242 GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGD 301
GVLLRY+PLTA+RVTGIVSRGGSIMAAWCLAHH+ESFLYT+F ELC+I YDVTFSLGD
Sbjct 245 GVLLRYIPLTARRVTGIVSRGGSIMAAWCLAHHQESFLYTHFSELCEILREYDVTFSLGD 304
Query 302 GLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELC 361
GLRPGSIADAND AQFAEL TLGELT IA+ H QVMIEGPGH+PMHKI ENV LEE+L
Sbjct 305 GLRPGSIADANDRAQFAELETLGELTHIAREHDVQVMIEGPGHVPMHKIKENVELEEKLT 364
Query 362 EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGV 421
EAPFYTLGPLATDIAPAYDHITSAIGAA I GTAMLCYVTPKEHLGLP+R DVK GV
Sbjct 365 GEAPFYTLGPLATDIAPAYDHITSAIGAAQIGWYGTAMLCYVTPKEHLGLPNRDDVKTGV 424
Query 422 IAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEP 481
I YKIAAHAADLAKGH AQ+ DD LS ARFEFRWNDQF LSLDPDTAR FHDETLPAEP
Sbjct 425 ITYKIAAHAADLAKGHQYAQDWDDELSKARFEFRWNDQFNLSLDPDTARSFHDETLPAEP 484
Query 482 AKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRV 541
AKTAHFCSMCGPKFCSMRITQDVR+YA EHGL + IE AGMAEKS EF+E GN+V
Sbjct 485 AKTAHFCSMCGPKFCSMRITQDVRKYAEEHGLSSVEAIE----AGMAEKSAEFSEQGNKV 540
Query 542 YLPITQ 547
YLP+
Sbjct 541 YLPVVN 546
>gi|325002845|ref|ZP_08123957.1| thiamine biosynthesis protein ThiC [Pseudonocardia sp. P1]
Length=548
Score = 858 bits (2216), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 426/543 (79%), Positives = 461/543 (85%), Gaps = 13/543 (2%)
Query 7 PSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDL 66
P VTTGPI GSAKA+ +E P + VP RR+ LS G+H D+YDTSGPYTD VID+
Sbjct 10 PQVTTGPITGSAKAW--VEGPDG---ISVPVRRIALSNGEHHDVYDTSGPYTDPTAVIDV 64
Query 67 TAGLP--HRP--GVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIP 122
AGLP P G D GTQL ARAG +T EM +IA RE AELVR EVARGRAVIP
Sbjct 65 GAGLPALRAPWIGGREDGGTQLSYARAGVVTEEMRWIAVRERCDAELVRSEVARGRAVIP 124
Query 123 ANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKN 182
AN +HPESEPMIIGK F KVNANIGNSAV+SSIA+EV+KMVWATRWGADT+MDLSTG++
Sbjct 125 ANVNHPESEPMIIGKRFLTKVNANIGNSAVSSSIADEVEKMVWATRWGADTVMDLSTGRD 184
Query 183 IHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAG 242
IH TRE ILRNSPVP+GTVPIYQALEKV DP EL+WE+YRDTVIEQCEQGVDYMTVHAG
Sbjct 185 IHTTRERILRNSPVPIGTVPIYQALEKVDSDPAELSWEVYRDTVIEQCEQGVDYMTVHAG 244
Query 243 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDG 302
VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+F ELC+I RYDVTFSLGDG
Sbjct 245 VLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFSELCEILRRYDVTFSLGDG 304
Query 303 LRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCE 362
LRPGSIADAND AQ AEL TLGELT+IAK+H QVMIEGPGH+PM KIVENVRLEEE C+
Sbjct 305 LRPGSIADANDTAQLAELETLGELTRIAKSHDVQVMIEGPGHVPMDKIVENVRLEEEWCD 364
Query 363 EAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVI 422
EAPFYTLGPLATDIAP YDHITSAIGAA IA+AGTAMLCYVTPKEHLGLP+R DVK GVI
Sbjct 365 EAPFYTLGPLATDIAPGYDHITSAIGAARIAEAGTAMLCYVTPKEHLGLPNRDDVKVGVI 424
Query 423 AYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPA 482
+YKIAAHAADLAKGHP AQ RDDALS ARFEFRW DQFALSLDPDTA+ +HDETLPAEPA
Sbjct 425 SYKIAAHAADLAKGHPHAQARDDALSQARFEFRWRDQFALSLDPDTAQAYHDETLPAEPA 484
Query 483 KTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVY 542
K+AHFCSMCGPKFCSM+ITQDVR+YA HGL + IE AGM EKS EF + G RVY
Sbjct 485 KSAHFCSMCGPKFCSMKITQDVRDYAEAHGLTSVEAIE----AGMEEKSGEFRDEGGRVY 540
Query 543 LPI 545
LPI
Sbjct 541 LPI 543
>gi|134097122|ref|YP_001102783.1| thiamine biosynthesis protein ThiC [Saccharopolyspora erythraea
NRRL 2338]
gi|133909745|emb|CAL99857.1| putative thiamine biosynthesis protein [Saccharopolyspora erythraea
NRRL 2338]
Length=547
Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 424/541 (79%), Positives = 459/541 (85%), Gaps = 12/541 (2%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
SVTTGPI+GS K + E+ L+VPFRR+ LS G+H D+YDTSG YTD D +D+
Sbjct 14 SVTTGPISGSRKVHHTTES-----GLKVPFRRIELSNGEHLDVYDTSGAYTDDDVQVDVH 68
Query 68 AGLPH-RPGVV--RDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPAN 124
+GL R G R+ TQL A+AG +T EM FIAARE +S E VRDEVA GRAVIPAN
Sbjct 69 SGLHRLRAGWTDGREHRTQLGWAKAGVVTREMEFIAAREGVSPEFVRDEVASGRAVIPAN 128
Query 125 HHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIH 184
HPESEPMIIGK F VKVNANIGNSAVTSS+ EEV+KMVWATRWGADT+MDLSTGK IH
Sbjct 129 RCHPESEPMIIGKNFLVKVNANIGNSAVTSSVEEEVEKMVWATRWGADTVMDLSTGKRIH 188
Query 185 ETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVL 244
ETRE ILRNSPVP+GTVPIYQALEKV GDP +LTWEIYRDTVIEQCEQGVDYMTVHAGVL
Sbjct 189 ETREQILRNSPVPIGTVPIYQALEKVNGDPEKLTWEIYRDTVIEQCEQGVDYMTVHAGVL 248
Query 245 LRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLR 304
LRYVPLTA+RVTGIVSRGGSIMAAWCLAHHRESFLYT+F ELC+I YDVTFSLGDGLR
Sbjct 249 LRYVPLTAQRVTGIVSRGGSIMAAWCLAHHRESFLYTHFSELCEILRDYDVTFSLGDGLR 308
Query 305 PGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEA 364
PGSIADAND AQFAEL TLGELT IA+ QVMIEGPGH+PMHKIVENV+LEEELC EA
Sbjct 309 PGSIADANDRAQFAELETLGELTHIARDMDVQVMIEGPGHVPMHKIVENVKLEEELCGEA 368
Query 365 PFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAY 424
PFYTLGPL TDIAPAYDHITS IGAA+IAQAGTAMLCYVTPKEHLGLP+R DVK GVI Y
Sbjct 369 PFYTLGPLTTDIAPAYDHITSGIGAAVIAQAGTAMLCYVTPKEHLGLPNRDDVKVGVITY 428
Query 425 KIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKT 484
KIAAHAADLAKGHPRAQ+ DDALS ARFEFRWNDQF LSLDPDTAR +HDETLPAEPAKT
Sbjct 429 KIAAHAADLAKGHPRAQDWDDALSKARFEFRWNDQFNLSLDPDTARAYHDETLPAEPAKT 488
Query 485 AHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLP 544
AHFCSMCGPKFCSM+ITQDVR+YA E GL + IE AGM EKS EF+E G +VYLP
Sbjct 489 AHFCSMCGPKFCSMKITQDVRKYAEERGLTSVEAIE----AGMREKSDEFSESGGKVYLP 544
Query 545 I 545
+
Sbjct 545 V 545
>gi|334563417|ref|ZP_08516408.1| thiamine biosynthesis protein ThiC [Corynebacterium bovis DSM
20582]
Length=574
Score = 855 bits (2210), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 428/555 (78%), Positives = 461/555 (84%), Gaps = 21/555 (3%)
Query 9 VTTGPIAGSAKAYREI---EAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVID 65
VTTGPI S K Y E+ G+ L++P R V L+TG F LYDTSG YT+ D +D
Sbjct 22 VTTGPIYRSRKTYTEVTHRNTDGTSTVLRIPQRSVDLTTGAQFPLYDTSGIYTEDDPQLD 81
Query 66 LTAGLPH-RPGVVRDRG-------------TQLQRARAGEITAEMAFIAAREDMSAELVR 111
L AGL R G R TQL ARAG +T EM FIA RE + E VR
Sbjct 82 LAAGLARTRDGWERPAAAPASAEHPELRVQTQLAWARAGVVTPEMTFIAHREGFTPEFVR 141
Query 112 DEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGA 171
DEVA GRAVI ANH HPE EPMIIG+AFAVK+NAN+GNSAVTSSIAEEV+KMVWATRWGA
Sbjct 142 DEVAAGRAVICANHRHPEIEPMIIGRAFAVKINANMGNSAVTSSIAEEVEKMVWATRWGA 201
Query 172 DTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCE 231
DTIMDLSTG +IHETREWI+RNSPVPVGTVPIY+ALEKVKGDP LTWEIYRDTVIEQCE
Sbjct 202 DTIMDLSTGSDIHETREWIIRNSPVPVGTVPIYEALEKVKGDPMALTWEIYRDTVIEQCE 261
Query 232 QGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFA 291
QGVDYMTVHAGVLLRYVPL A RVTGIVSRGGSIMAAWCL HRESFLYT+FEELCDI A
Sbjct 262 QGVDYMTVHAGVLLRYVPLAAPRVTGIVSRGGSIMAAWCLKEHRESFLYTHFEELCDILA 321
Query 292 RYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIV 351
RYDVTFSLGDGLRPGSIADAND AQ AELRTLGELT+IA++ G QVMIEGPGH+PMHKI
Sbjct 322 RYDVTFSLGDGLRPGSIADANDEAQLAELRTLGELTRIARSRGVQVMIEGPGHVPMHKIP 381
Query 352 ENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGL 411
+NV EEE C+ APFYTLGPLATDIAP YDHITSAIGAAII QAGTAMLCYVTPKEHLGL
Sbjct 382 QNVEWEEEWCDGAPFYTLGPLATDIAPGYDHITSAIGAAIIGQAGTAMLCYVTPKEHLGL 441
Query 412 PDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTARE 471
P+R DVK GVI YKIAAHAADLAKGHPRAQERDDALSTARFEFRW+DQFAL+LDPDTA +
Sbjct 442 PNRDDVKTGVITYKIAAHAADLAKGHPRAQERDDALSTARFEFRWHDQFALALDPDTALD 501
Query 472 FHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKS 531
FHDETLPAEPAKTAHFCSMCGPKFCSMRI+QDVR+YA EHGL + IE AGMAEKS
Sbjct 502 FHDETLPAEPAKTAHFCSMCGPKFCSMRISQDVRDYAEEHGLTSVEAIE----AGMAEKS 557
Query 532 REFAEHGNRVYLPIT 546
+EF+E G+RVYLPIT
Sbjct 558 QEFSEAGDRVYLPIT 572
>gi|300790377|ref|YP_003770668.1| thiamine biosynthesis protein ThiC [Amycolatopsis mediterranei
U32]
gi|299799891|gb|ADJ50266.1| thiamine biosynthesis protein ThiC [Amycolatopsis mediterranei
U32]
gi|340532061|gb|AEK47266.1| thiamine biosynthesis protein ThiC [Amycolatopsis mediterranei
S699]
Length=536
Score = 855 bits (2209), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 420/542 (78%), Positives = 458/542 (85%), Gaps = 12/542 (2%)
Query 9 VTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTA 68
VTTGPI GS KAY++ E+ L+VP RR+ LS G+ FD+YDTSGPYTD D ID+ +
Sbjct 3 VTTGPITGSHKAYQQTES-----GLRVPVRRIDLSNGEQFDVYDTSGPYTDPDVEIDVHS 57
Query 69 GLPH-RPGVV--RDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANH 125
GL R G R+ TQL A+ G IT EM +IAARE +S E VRDEVARGRAVIPAN
Sbjct 58 GLHRLRAGWADGREHNTQLGWAKQGVITREMEYIAARERVSPEFVRDEVARGRAVIPANR 117
Query 126 HHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHE 185
HPE+EPMIIGK F VK+NAN+GNSAV SS+ EEVDKMVWATRWGADTIMDLSTGK IHE
Sbjct 118 KHPETEPMIIGKNFLVKINANMGNSAVWSSVEEEVDKMVWATRWGADTIMDLSTGKRIHE 177
Query 186 TREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLL 245
TREWI+RNSPVPVGTVPIYQALEKV G+P +L+WE+YRDT+IEQCEQGVDY+TVHAGVLL
Sbjct 178 TREWIIRNSPVPVGTVPIYQALEKVDGEPEKLSWEVYRDTIIEQCEQGVDYVTVHAGVLL 237
Query 246 RYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRP 305
RY+PLTA+RVTGIVSRGGSIMAAWCLAHH+ESFLYT+FEELC+I +YDVTFSLGDGLRP
Sbjct 238 RYIPLTARRVTGIVSRGGSIMAAWCLAHHQESFLYTHFEELCEILRQYDVTFSLGDGLRP 297
Query 306 GSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAP 365
GSIADAND AQFAEL TLGELT IA++H QVMIEGPGH+PMHKI ENV LEE+LC EAP
Sbjct 298 GSIADANDRAQFAELETLGELTHIARSHDVQVMIEGPGHVPMHKIKENVELEEKLCGEAP 357
Query 366 FYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYK 425
FYTLGPLATDIAPAYDHITSAIGAA I GTAMLCYVTPKEHLGLP+R DVK GVI YK
Sbjct 358 FYTLGPLATDIAPAYDHITSAIGAAQIGWYGTAMLCYVTPKEHLGLPNRDDVKTGVITYK 417
Query 426 IAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTA 485
IAAHAADLAKGH AQE DD LS ARFEFRWNDQF LSLDPDTAR FHDETLPAEPAKTA
Sbjct 418 IAAHAADLAKGHKYAQEWDDELSKARFEFRWNDQFNLSLDPDTARSFHDETLPAEPAKTA 477
Query 486 HFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
HFCSMCGPKFCSMRITQDVR+YA EHGL T IE AGMA KS EF E G +VYLP+
Sbjct 478 HFCSMCGPKFCSMRITQDVRKYAEEHGLSTVEAIE----AGMASKSAEFTESGGQVYLPV 533
Query 546 TQ 547
Q
Sbjct 534 VQ 535
>gi|317506799|ref|ZP_07964574.1| ThiC family protein [Segniliparus rugosus ATCC BAA-974]
gi|316254910|gb|EFV14205.1| ThiC family protein [Segniliparus rugosus ATCC BAA-974]
Length=539
Score = 848 bits (2191), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 431/543 (80%), Positives = 467/543 (87%), Gaps = 18/543 (3%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
++T GP+ GS+K Y E + L+VPFRRVHL+ G+ DLYDTSGPYT+ D IDL
Sbjct 9 ALTLGPLPGSSKHYMEHDG------LRVPFRRVHLTNGEQVDLYDTSGPYTEDDPQIDLG 62
Query 68 AGLPH-RPGVVRDRG---TQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPA 123
GLP R R G TQL+ ARAG +T EM FIAARE ++ ELV EVA GRAVIPA
Sbjct 63 RGLPKLRDQWSRPDGPFRTQLEHARAGVLTPEMRFIAAREGVAEELVLQEVAAGRAVIPA 122
Query 124 NHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNI 183
N +HPE EPMIIGKAF VK+NANIGNSAVTSSIAEEV+KMVWATRWGAD IMDLSTG +I
Sbjct 123 NRNHPEIEPMIIGKAFRVKINANIGNSAVTSSIAEEVEKMVWATRWGADNIMDLSTGADI 182
Query 184 HETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGV 243
HETREWILRNSPVPVGTVPIYQALEKV GDP +LTWE+YRDT++EQCEQGVDYMTVHAGV
Sbjct 183 HETREWILRNSPVPVGTVPIYQALEKVNGDPVKLTWELYRDTIVEQCEQGVDYMTVHAGV 242
Query 244 LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGL 303
LLR+VPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYT+FEELC+I YDVTFSLGDGL
Sbjct 243 LLRHVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFEELCEILRAYDVTFSLGDGL 302
Query 304 RPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEE 363
RPGSIADANDAAQFAEL TLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEELCEE
Sbjct 303 RPGSIADANDAAQFAELATLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELCEE 362
Query 364 APFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIA 423
APFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP+R DVK GVIA
Sbjct 363 APFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPNRDDVKAGVIA 422
Query 424 YKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAK 483
YKIAAHAADLAKGHP+AQERDDALS ARFEFRW+DQFALSLDPDTA +HDETLPAEPAK
Sbjct 423 YKIAAHAADLAKGHPKAQERDDALSKARFEFRWHDQFALSLDPDTAMAYHDETLPAEPAK 482
Query 484 TAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYL 543
AHFCSMCGPKFCSMRI+ D+RE AA EA++A G +KSREFAE G VYL
Sbjct 483 KAHFCSMCGPKFCSMRISADIREQAAAQ--------EALIAEGFEQKSREFAEAGGSVYL 534
Query 544 PIT 546
PI+
Sbjct 535 PIS 537
>gi|256374578|ref|YP_003098238.1| thiamine biosynthesis protein ThiC [Actinosynnema mirum DSM 43827]
gi|255918881|gb|ACU34392.1| thiamine biosynthesis protein ThiC [Actinosynnema mirum DSM 43827]
Length=547
Score = 845 bits (2184), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 419/549 (77%), Positives = 454/549 (83%), Gaps = 18/549 (3%)
Query 4 TVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTV 63
+V PSVTTGPI GS K +R+ E ++VPFRRV L+ GDHFDLYDTSGPYT D
Sbjct 8 SVRPSVTTGPIRGSRKVHRDAED-----GVRVPFRRVELTDGDHFDLYDTSGPYTAGD-- 60
Query 64 IDLTAGLPH-RPGVVRDR------GTQLQRARAGEITAEMAFIAAREDMSAELVRDEVAR 116
+D+ GL R G + R TQL ARAG IT EM F A RE ++ E VRDEVA
Sbjct 61 VDVREGLEKIRAGWISAREPVNGAATQLAWARAGVITPEMRFAALRESLAPEFVRDEVAA 120
Query 117 GRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMD 176
GRAVIPAN +HPESEPM+IGK F VKVNANIGNSAVTSS+ EEV+KMVWATRWGADT+MD
Sbjct 121 GRAVIPANRNHPESEPMVIGKGFLVKVNANIGNSAVTSSVEEEVEKMVWATRWGADTVMD 180
Query 177 LSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDY 236
LSTGK IHETREWI+RNSPVPVGTVPIYQALEKV GDP L+WE+YRDTV+EQ EQGVDY
Sbjct 181 LSTGKRIHETREWIIRNSPVPVGTVPIYQALEKVGGDPAALSWEVYRDTVVEQAEQGVDY 240
Query 237 MTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVT 296
MTVHAGVLLRYVPLTA+RVTGIVSRGGSIMAAWCLAHH ESFLYT F ELC+I +YDVT
Sbjct 241 MTVHAGVLLRYVPLTARRVTGIVSRGGSIMAAWCLAHHEESFLYTRFAELCEILRQYDVT 300
Query 297 FSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRL 356
FSLGDGLRPGSIADAND AQFAELRTLGEL ++A+AH QVMIEGPGH+P+HKI ENVRL
Sbjct 301 FSLGDGLRPGSIADANDEAQFAELRTLGELARVARAHDVQVMIEGPGHVPLHKIAENVRL 360
Query 357 EEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKD 416
E+E C+ APFYTLGPLATD+APAYDHITSAIGAA I GTAMLCYVTPKEHLGLPDR D
Sbjct 361 EQEWCDGAPFYTLGPLATDVAPAYDHITSAIGAAQIGALGTAMLCYVTPKEHLGLPDRDD 420
Query 417 VKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDET 476
VK GVI YKIAAHAADLAKGHP AQ DDALS ARFEFRW DQF LSLDPDTAREFHD T
Sbjct 421 VKTGVITYKIAAHAADLAKGHPGAQAWDDALSRARFEFRWEDQFNLSLDPDTAREFHDRT 480
Query 477 LPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAE 536
LPAEPAKTAHFCSMCGPKFCSMRITQDVR YA E GL T IE AGMAEK+ EF +
Sbjct 481 LPAEPAKTAHFCSMCGPKFCSMRITQDVRRYAEERGLSTVEAIE----AGMAEKAHEFDD 536
Query 537 HGNRVYLPI 545
G +VYLP+
Sbjct 537 RGGKVYLPV 545
>gi|213964640|ref|ZP_03392840.1| thiamine biosynthesis protein ThiC [Corynebacterium amycolatum
SK46]
gi|213952833|gb|EEB64215.1| thiamine biosynthesis protein ThiC [Corynebacterium amycolatum
SK46]
Length=568
Score = 842 bits (2175), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 427/558 (77%), Positives = 471/558 (85%), Gaps = 21/558 (3%)
Query 6 EPSVTTGPIAGSAKAYREIEAPG--SGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTV 63
E VTTGPI S K Y E+ A L++P RR++L+ G HFD YDTSG YT+ +
Sbjct 13 EGEVTTGPIYRSNKHYGEVAFSNDFGEANLRIPVRRINLTDGTHFDAYDTSGIYTEENPK 72
Query 64 IDLTAGL-------PHRPGVVRDRG--------TQLQRARAGEITAEMAFIAAREDMSAE 108
++L GL P P V G TQL ARAG +T EMAFIAARE++ E
Sbjct 73 LNLKEGLAKTRDSWPKAPAVPAVAGSEEAPKVKTQLAWARAGIVTPEMAFIAARENVDPE 132
Query 109 LVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATR 168
+VR+EVA GRAVIPANH HPE+EPMIIGK FA K+NANIGNSAVTSSI+EEV+KMVWATR
Sbjct 133 IVREEVAAGRAVIPANHKHPETEPMIIGKRFATKINANIGNSAVTSSISEEVEKMVWATR 192
Query 169 WGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIE 228
WGADTIMDLSTGK+IHETREWILRNSPVPVGTVPIYQALEKVKGDP +LTWEIYR+T+IE
Sbjct 193 WGADTIMDLSTGKDIHETREWILRNSPVPVGTVPIYQALEKVKGDPAKLTWEIYRETIIE 252
Query 229 QCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCD 288
QCEQGVDYMTVHAGVLLRYVPL A RVTGIVSRGGSIMAAWCLAHH+ESFLYT F ELCD
Sbjct 253 QCEQGVDYMTVHAGVLLRYVPLAANRVTGIVSRGGSIMAAWCLAHHQESFLYTRFAELCD 312
Query 289 IFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMH 348
I A+YDVTFSLGDGLRPGSIADAND AQ AELRTLGELTKIAK+ G QVMIEGPGH+PMH
Sbjct 313 ILAQYDVTFSLGDGLRPGSIADANDEAQLAELRTLGELTKIAKSRGCQVMIEGPGHVPMH 372
Query 349 KIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEH 408
KI +NV+ EEE CEEAPFYTLGPLATDIAP YDHITSAIGAAIIAQAGTAMLCYVTPKEH
Sbjct 373 KIADNVKWEEEWCEEAPFYTLGPLATDIAPGYDHITSAIGAAIIAQAGTAMLCYVTPKEH 432
Query 409 LGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDT 468
LGLP+R DVK GVI YKI+AHAADLAKG PRAQERDDALS ARFEFRW+DQFAL+LDPDT
Sbjct 433 LGLPNRDDVKVGVITYKISAHAADLAKGLPRAQERDDALSKARFEFRWHDQFALALDPDT 492
Query 469 AREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMA 528
A ++HDETLPAEPAKTAHFCSMCGPKFCSMRI++DV++YA EHGL++ IE AGMA
Sbjct 493 ALDYHDETLPAEPAKTAHFCSMCGPKFCSMRISKDVQDYAKEHGLDSVEAIE----AGMA 548
Query 529 EKSREFAEHGNRVYLPIT 546
EKS+EFA+ G+RVYLPIT
Sbjct 549 EKSQEFADQGSRVYLPIT 566
>gi|291009661|ref|ZP_06567634.1| thiamine biosynthesis protein ThiC [Saccharopolyspora erythraea
NRRL 2338]
Length=512
Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 411/514 (80%), Positives = 443/514 (87%), Gaps = 7/514 (1%)
Query 35 VPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPH-RPGVV--RDRGTQLQRARAGE 91
+PFRR+ LS G+H D+YDTSG YTD D +D+ +GL R G R+ TQL A+AG
Sbjct 1 MPFRRIELSNGEHLDVYDTSGAYTDDDVQVDVHSGLHRLRAGWTDGREHRTQLGWAKAGV 60
Query 92 ITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSA 151
+T EM FIAARE +S E VRDEVA GRAVIPAN HPESEPMIIGK F VKVNANIGNSA
Sbjct 61 VTREMEFIAAREGVSPEFVRDEVASGRAVIPANRCHPESEPMIIGKNFLVKVNANIGNSA 120
Query 152 VTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVK 211
VTSS+ EEV+KMVWATRWGADT+MDLSTGK IHETRE ILRNSPVP+GTVPIYQALEKV
Sbjct 121 VTSSVEEEVEKMVWATRWGADTVMDLSTGKRIHETREQILRNSPVPIGTVPIYQALEKVN 180
Query 212 GDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCL 271
GDP +LTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTA+RVTGIVSRGGSIMAAWCL
Sbjct 181 GDPEKLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAQRVTGIVSRGGSIMAAWCL 240
Query 272 AHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAK 331
AHHRESFLYT+F ELC+I YDVTFSLGDGLRPGSIADAND AQFAEL TLGELT IA+
Sbjct 241 AHHRESFLYTHFSELCEILRDYDVTFSLGDGLRPGSIADANDRAQFAELETLGELTHIAR 300
Query 332 AHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAI 391
QVMIEGPGH+PMHKIVENV+LEEELC EAPFYTLGPL TDIAPAYDHITS IGAA+
Sbjct 301 DMDVQVMIEGPGHVPMHKIVENVKLEEELCGEAPFYTLGPLTTDIAPAYDHITSGIGAAV 360
Query 392 IAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTAR 451
IAQAGTAMLCYVTPKEHLGLP+R DVK GVI YKIAAHAADLAKGHPRAQ+ DDALS AR
Sbjct 361 IAQAGTAMLCYVTPKEHLGLPNRDDVKVGVITYKIAAHAADLAKGHPRAQDWDDALSKAR 420
Query 452 FEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEH 511
FEFRWNDQF LSLDPDTAR +HDETLPAEPAKTAHFCSMCGPKFCSM+ITQDVR+YA E
Sbjct 421 FEFRWNDQFNLSLDPDTARAYHDETLPAEPAKTAHFCSMCGPKFCSMKITQDVRKYAEER 480
Query 512 GLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
GL + IE AGM EKS EF+E G +VYLP+
Sbjct 481 GLTSVEAIE----AGMREKSDEFSESGGKVYLPV 510
>gi|296393667|ref|YP_003658551.1| thiamine biosynthesis protein ThiC [Segniliparus rotundus DSM
44985]
gi|296180814|gb|ADG97720.1| thiamine biosynthesis protein ThiC [Segniliparus rotundus DSM
44985]
Length=552
Score = 837 bits (2163), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 423/545 (78%), Positives = 464/545 (86%), Gaps = 22/545 (4%)
Query 8 SVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLT 67
++T GP+ GSAK Y + L+VP RRVHL+ G++ DLYD SGPYT+ + IDL
Sbjct 22 ALTLGPLTGSAKQYEQ------HGELRVPVRRVHLTNGENVDLYDASGPYTEDNPAIDLR 75
Query 68 AGLPH------RPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVI 121
GLP RPG TQL+ ARAG +T EM FIA RE ++ ELV EVA GRAVI
Sbjct 76 RGLPKLRDQWSRPG--GPFRTQLEHARAGVLTPEMRFIAVREGVAPELVLREVAAGRAVI 133
Query 122 PANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGK 181
PAN +HPE EPM+IGKAF VK+NANIGNSAVTSS+AEEV+KMVWATRWGAD IMDLSTG
Sbjct 134 PANRNHPEVEPMVIGKAFRVKINANIGNSAVTSSVAEEVEKMVWATRWGADNIMDLSTGN 193
Query 182 NIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHA 241
+IHETREWILRNSPVPVGTVPIYQALEK GDP +LTWE+YR+TV+EQCEQGVDYMTVHA
Sbjct 194 DIHETREWILRNSPVPVGTVPIYQALEKANGDPVKLTWELYRETVLEQCEQGVDYMTVHA 253
Query 242 GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGD 301
GVLLR+VPLTAKRVTGIVSRGGSIMAAWCLAHH+ESFLYT+F ELC+I YDVTFSLGD
Sbjct 254 GVLLRHVPLTAKRVTGIVSRGGSIMAAWCLAHHQESFLYTHFAELCEILRDYDVTFSLGD 313
Query 302 GLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELC 361
GLRPGSIADAND AQFAELRTLGELTKIAK+HG QVMIEGPGH+PMHKIVENVRLEEELC
Sbjct 314 GLRPGSIADANDEAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELC 373
Query 362 EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGV 421
EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLP+R DVK GV
Sbjct 374 EEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPNRDDVKAGV 433
Query 422 IAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEP 481
IAYKIAAHAADLAKGHP+AQERDDALS ARFEFRW+DQFALSLDPDTA +HDETLPAEP
Sbjct 434 IAYKIAAHAADLAKGHPKAQERDDALSKARFEFRWHDQFALSLDPDTAMAYHDETLPAEP 493
Query 482 AKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRV 541
AK AHFCSMCGPKFCSMRI+ D+RE AA H EA++A G +KSREFAE G +V
Sbjct 494 AKKAHFCSMCGPKFCSMRISADIREQAAAH--------EALIAEGFEQKSREFAEAGAQV 545
Query 542 YLPIT 546
YLPI+
Sbjct 546 YLPIS 550
>gi|226304977|ref|YP_002764935.1| thiamine biosynthesis protein ThiC [Rhodococcus erythropolis
PR4]
gi|226184092|dbj|BAH32196.1| thiamine biosynthesis protein ThiC [Rhodococcus erythropolis
PR4]
Length=543
Score = 832 bits (2149), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 411/511 (81%), Positives = 442/511 (87%), Gaps = 15/511 (2%)
Query 4 TVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTV 63
TV +VTTGPI GS+K Y E + +L+VP RRV L+ G+H DLYDTSGPYTDTD
Sbjct 13 TVHTAVTTGPIEGSSKHYVESD------SLRVPLRRVTLTNGEHLDLYDTSGPYTDTDAD 66
Query 64 IDLTAGLP------HRPGVVRDRGTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARG 117
IDL AGLP RP R TQL+ AR G IT EM + AARE +SAELV EVARG
Sbjct 67 IDLDAGLPTTRDTWERPESNR---TQLECARDGVITPEMRYCAAREGVSAELVLSEVARG 123
Query 118 RAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDL 177
RAVIPANH H E EPMIIGK FAVK+NANIGNSAVTSS+AEEV+KMVWA RWGADTIMDL
Sbjct 124 RAVIPANHRHGELEPMIIGKKFAVKINANIGNSAVTSSVAEEVEKMVWAIRWGADTIMDL 183
Query 178 STGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYM 237
STGK+IH TREWILRNSPVPVGTVPIYQALEKV GDPT LTWEIYRDTVIEQCEQGVDYM
Sbjct 184 STGKDIHLTREWILRNSPVPVGTVPIYQALEKVNGDPTALTWEIYRDTVIEQCEQGVDYM 243
Query 238 TVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTF 297
TVHAGV + Y+ LTA RVTGIVSRGG+IMAAWC+ H +ESFLYT+F+ELC+I RYDVTF
Sbjct 244 TVHAGVRIGYIALTAGRVTGIVSRGGAIMAAWCMHHRQESFLYTHFDELCEILRRYDVTF 303
Query 298 SLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLE 357
SLGDGLRPGSIADANDAAQFAELRTLGELT+IAK+ G QVMIEGPGH+PM KI ENVRLE
Sbjct 304 SLGDGLRPGSIADANDAAQFAELRTLGELTQIAKSAGVQVMIEGPGHVPMDKIEENVRLE 363
Query 358 EELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDV 417
EELC+EAPFYTLGPLATDIAPAYDHITSAIGAA+IA+AGTAMLCYVTPKEHLGLP+R DV
Sbjct 364 EELCDEAPFYTLGPLATDIAPAYDHITSAIGAAMIARAGTAMLCYVTPKEHLGLPNRDDV 423
Query 418 KDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETL 477
K GVI YKIAAHAADLAKGHP AQ RDDALS ARFEFRW DQFALSLDPDTAREFHDETL
Sbjct 424 KTGVITYKIAAHAADLAKGHPNAQARDDALSKARFEFRWLDQFALSLDPDTAREFHDETL 483
Query 478 PAEPAKTAHFCSMCGPKFCSMRITQDVREYA 508
PAEPAKTAHFCSMCGPKFCSMRI+ DVR+YA
Sbjct 484 PAEPAKTAHFCSMCGPKFCSMRISADVRQYA 514
>gi|331699884|ref|YP_004336123.1| phosphomethylpyrimidine synthase [Pseudonocardia dioxanivorans
CB1190]
gi|326954573|gb|AEA28270.1| Phosphomethylpyrimidine synthase [Pseudonocardia dioxanivorans
CB1190]
Length=564
Score = 815 bits (2104), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 405/556 (73%), Positives = 449/556 (81%), Gaps = 21/556 (3%)
Query 4 TVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYT----- 58
+V P VTTGPI GS KAY + P +++P RR+ L+TG+ D+YDTSGPYT
Sbjct 6 SVRPQVTTGPITGSHKAY--LHGPRG---MRIPVRRIALTTGESLDVYDTSGPYTHDAAT 60
Query 59 DTDTVIDLTAGLPH-RPGVVRDRG------TQLQRARAGEITAEMAFIAAREDMSAELVR 111
+DL AGLP R + +R TQL ARAG +T EM F+A RE + AELVR
Sbjct 61 AAAPAVDLHAGLPALRADWIAEREPIGGAVTQLAYARAGIVTPEMEFVAVREGVDAELVR 120
Query 112 DEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEVDKMVWATRWGA 171
EVARGRAVIPAN HPE+EPMIIG F VKVNANIGNSAV SSI +EV+K+VWATRWGA
Sbjct 121 SEVARGRAVIPANRRHPETEPMIIGNRFLVKVNANIGNSAVRSSIEDEVEKLVWATRWGA 180
Query 172 DTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCE 231
DT+MDLSTG +IH TREWILRNSPVPVGTVPIYQALEKV GDP L+WE+YRDTVIEQCE
Sbjct 181 DTVMDLSTGSDIHRTREWILRNSPVPVGTVPIYQALEKVNGDPAALSWEVYRDTVIEQCE 240
Query 232 QGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFA 291
QGVDYMTVHAGVLLRYVPLTA RVTGIVSRGGSIMAAWCLAHHRESFLYT+F ELC I
Sbjct 241 QGVDYMTVHAGVLLRYVPLTAARVTGIVSRGGSIMAAWCLAHHRESFLYTHFAELCAILR 300
Query 292 RYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIV 351
YDVTFSLGDGLRPGSIADAND AQ AELRTLGELT IA+ H QVM+EGPGH+PM+KIV
Sbjct 301 AYDVTFSLGDGLRPGSIADANDEAQLAELRTLGELTAIAREHDVQVMVEGPGHVPMNKIV 360
Query 352 ENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGL 411
ENV L + C+EAPFYTLGPL TDIAP YDHITSAIGAA IAQAGTAMLCYVTPKEHLGL
Sbjct 361 ENVELARQWCDEAPFYTLGPLTTDIAPGYDHITSAIGAARIAQAGTAMLCYVTPKEHLGL 420
Query 412 PDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTARE 471
PDR DVK GVI+Y+IAAHAADLAKGHP+AQ RDDALS ARFEFRW+DQFAL+LDPDTAR
Sbjct 421 PDRDDVKTGVISYRIAAHAADLAKGHPQAQARDDALSRARFEFRWHDQFALALDPDTARS 480
Query 472 FHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKS 531
FHDETLPAE AK+AHFCSMCGPKFCSMRI+ D+R+ G +E AGM +K+
Sbjct 481 FHDETLPAEAAKSAHFCSMCGPKFCSMRISHDIRDRTGAAGPAGAEAVE----AGMRQKA 536
Query 532 REFAEHGNRVYLPITQ 547
REFA+ G RVYLP+T
Sbjct 537 REFADAGGRVYLPVTS 552
>gi|288923395|ref|ZP_06417523.1| thiamine biosynthesis protein ThiC [Frankia sp. EUN1f]
gi|288345257|gb|EFC79658.1| thiamine biosynthesis protein ThiC [Frankia sp. EUN1f]
Length=627
Score = 801 bits (2069), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 401/578 (70%), Positives = 442/578 (77%), Gaps = 53/578 (9%)
Query 13 PIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPH 72
P GS K Y GS LQVP R V LSTGD LYDTSGPYTD +D+ GL
Sbjct 52 PFPGSRKTYLT----GSRPDLQVPMREVALSTGDSLVLYDTSGPYTDPGAGVDVRRGLQA 107
Query 73 -RPGVVRDRG--------------------------------------------TQLQRA 87
R + DR TQL A
Sbjct 108 LRSSWIIDRADTEEITGRAVQPADDGRSRTSAPEADLFIGSARAPRRALAGQAVTQLAYA 167
Query 88 RAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANI 147
R GEIT EM F+A RE ++ ELVRDE+A GRAV+PAN +HPESEPM IG+ VK+NANI
Sbjct 168 RRGEITPEMEFVALREGLAPELVRDEIAAGRAVLPANVNHPESEPMAIGRNLLVKINANI 227
Query 148 GNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQAL 207
GNSAV SSI EEV+KMVWATRWGADT+MDLSTG+NIH TREWI+RNSPVP+GTVPIYQAL
Sbjct 228 GNSAVASSIEEEVEKMVWATRWGADTVMDLSTGRNIHTTREWIIRNSPVPIGTVPIYQAL 287
Query 208 EKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMA 267
EKV G ELTWE+YRDTVIEQ EQGVDYMTVHAGVLLRYVP+TAKR TGIVSRGGSI+A
Sbjct 288 EKVGGKAEELTWEVYRDTVIEQAEQGVDYMTVHAGVLLRYVPMTAKRKTGIVSRGGSILA 347
Query 268 AWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELT 327
AWCLAHH+E+FLYTNF ELC+I YDVTFSLGDGLRPGSIADAND AQ AEL TLGELT
Sbjct 348 AWCLAHHQENFLYTNFAELCEILRAYDVTFSLGDGLRPGSIADANDTAQLAELATLGELT 407
Query 328 KIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAI 387
++A H QVMIEGPGH+PMHKI EN+ L+ ELC +APFYTLGPL TDIAP YDHITSAI
Sbjct 408 QVAWEHDVQVMIEGPGHVPMHKIKENMDLQAELCHDAPFYTLGPLTTDIAPGYDHITSAI 467
Query 388 GAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDAL 447
GAA+I GTAMLCYVTPKEHLGLPDR+DVK GVIAYKIAAHAADLAKGHP AQ DDAL
Sbjct 468 GAAMIGWYGTAMLCYVTPKEHLGLPDREDVKAGVIAYKIAAHAADLAKGHPGAQAWDDAL 527
Query 448 STARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREY 507
S ARF+FRW+DQF LSLDP+TARE+HDETLPA PAK AHFCSMCGP FCSMRITQDVR+Y
Sbjct 528 SDARFDFRWDDQFNLSLDPETAREYHDETLPAAPAKAAHFCSMCGPHFCSMRITQDVRKY 587
Query 508 AAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
AAEHGLETE ++ AG+AEKSREFAE G+R+YLP+
Sbjct 588 AAEHGLETEEAVQ----AGLAEKSREFAEQGSRIYLPL 621
>gi|158317358|ref|YP_001509866.1| thiamine biosynthesis protein ThiC [Frankia sp. EAN1pec]
gi|158112763|gb|ABW14960.1| thiamine biosynthesis protein ThiC [Frankia sp. EAN1pec]
Length=606
Score = 798 bits (2060), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 399/578 (70%), Positives = 444/578 (77%), Gaps = 53/578 (9%)
Query 13 PIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPH 72
P GS K Y GS L+VP R V LSTGD LYDTSGPYTD +D+ GLP
Sbjct 31 PFPGSRKTY----LVGSRPDLRVPMREVALSTGDSLVLYDTSGPYTDPGAGVDVRRGLPA 86
Query 73 -RPGVVRDRG--------------------------------------------TQLQRA 87
R G + RG TQL A
Sbjct 87 LRAGWIAARGDTEEIEGRAVQPADDGRRGPDGQAGDTFLGSGQAPRRATAGRAVTQLAYA 146
Query 88 RAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANI 147
R GEITAEM F+A RE +S ELVRDE+A GRAV+PAN +HPESEPM IG+ VK+NANI
Sbjct 147 RRGEITAEMEFVALREGLSPELVRDEIAAGRAVLPANVNHPESEPMAIGRNLLVKINANI 206
Query 148 GNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQAL 207
GNSAV SSI EEV+KMVW+TRWGADT+MDLSTG+NIH TREWI+RNSPVP+GTVPIYQAL
Sbjct 207 GNSAVASSIEEEVEKMVWSTRWGADTVMDLSTGRNIHTTREWIIRNSPVPIGTVPIYQAL 266
Query 208 EKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMA 267
EKV G ELTWE+YRDTVIEQ EQGVDYMTVHAGVLLRYVP+TA+R TGIVSRGGSI+A
Sbjct 267 EKVGGKAEELTWEVYRDTVIEQAEQGVDYMTVHAGVLLRYVPMTARRKTGIVSRGGSILA 326
Query 268 AWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELT 327
AWCLAHH E+FLYTNF ELC+I YDVTFSLGDGLRPGSI+DANDAAQ AEL TLGELT
Sbjct 327 AWCLAHHEENFLYTNFAELCEILRAYDVTFSLGDGLRPGSISDANDAAQLAELATLGELT 386
Query 328 KIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAI 387
+A H QVMIEGPGH+PMHKI ENV L+ ELC +APFYTLGPL TDIAP YDHITSAI
Sbjct 387 SVAWEHDVQVMIEGPGHVPMHKIKENVDLQRELCHDAPFYTLGPLTTDIAPGYDHITSAI 446
Query 388 GAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDAL 447
GAA+I GTAMLCYVTPKEHLGLPDR+DVK GVIAYKIAAHAADLAKGHP +Q DDAL
Sbjct 447 GAAMIGWYGTAMLCYVTPKEHLGLPDREDVKAGVIAYKIAAHAADLAKGHPGSQAWDDAL 506
Query 448 STARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREY 507
S ARF+FRW+DQF LSLDP+TARE+HDETLPA PAK+AHFCSMCGP FCSMRITQDVR+Y
Sbjct 507 SDARFDFRWDDQFNLSLDPETAREYHDETLPAAPAKSAHFCSMCGPHFCSMRITQDVRKY 566
Query 508 AAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
AA+HGL+T+ ++ AG+AEKSREFAE G R+YLP+
Sbjct 567 AADHGLDTDEAVQ----AGLAEKSREFAEQGARIYLPL 600
>gi|345016397|ref|YP_004818751.1| phosphomethylpyrimidine synthase [Streptomyces violaceusniger
Tu 4113]
gi|344042746|gb|AEM88471.1| Phosphomethylpyrimidine synthase [Streptomyces violaceusniger
Tu 4113]
Length=587
Score = 792 bits (2045), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 398/569 (70%), Positives = 437/569 (77%), Gaps = 56/569 (9%)
Query 27 PGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGL-PHRPGVVRDRG---- 81
PGS L VP RRVHL+ G LYDTSGPYTD D+ GL P R + RG
Sbjct 23 PGSRPDLHVPVRRVHLTNGQDVTLYDTSGPYTDPTIETDVRRGLAPLRQNWIVARGDTEE 82
Query 82 ---------------------------------------------TQLQRARAGEITAEM 96
TQL AR GE+TAEM
Sbjct 83 YAGRPVRPEDDGIKHTSPRGGLRNLDAVFPGRPRQPRRGRAGVPVTQLAYARRGEVTAEM 142
Query 97 AFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSI 156
++A RE++S E+VR+E+A GRAV+PAN +HPE EPMIIGK F VKVNANIGNSAVTSSI
Sbjct 143 EYVAIRENVSPEVVREEIAAGRAVLPANVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSI 202
Query 157 AEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTE 216
EEV+KM WATRWGADT+MDLSTG+NIH TREW+LRNSPVP+GTVP+YQALEKV G E
Sbjct 203 EEEVEKMTWATRWGADTVMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEE 262
Query 217 LTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRE 276
LTWEIY+DTVIEQ EQGVDYMTVHAGV L YVPLTA+R TGIVSRGGSIMAAWCLAHH+E
Sbjct 263 LTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTARRKTGIVSRGGSIMAAWCLAHHQE 322
Query 277 SFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGAQ 336
SFLYT+FEELC+I A YDVT+SLGDGLRPGSIADAND AQFAELRTLGEL +IAK HG Q
Sbjct 323 SFLYTHFEELCEILAAYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNRIAKEHGVQ 382
Query 337 VMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAG 396
MIEGPGH+PMHKI ENV L++E+CEEAPFYTLGPL TDIAPAYDHITS IGAA+IA G
Sbjct 383 TMIEGPGHVPMHKIKENVDLQQEICEEAPFYTLGPLTTDIAPAYDHITSGIGAAMIAWWG 442
Query 397 TAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRW 456
TAMLCYVTPKEHLGLPDR DVK GVI YKIAAHAADLAKGHP AQ DDALS ARFEFRW
Sbjct 443 TAMLCYVTPKEHLGLPDRDDVKTGVITYKIAAHAADLAKGHPDAQAWDDALSDARFEFRW 502
Query 457 NDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETE 516
DQF L+LDPDTAR FHDETLPAEPAKTAHFCSMCGP+FCSM+I+QD+R EHG +
Sbjct 503 EDQFNLALDPDTARSFHDETLPAEPAKTAHFCSMCGPRFCSMKISQDIRR---EHGGAMD 559
Query 517 ADIEAVLAAGMAEKSREFAEHGNRVYLPI 545
A A AGMA+KS+EFAE GNRVYLPI
Sbjct 560 A---AEAEAGMAQKSKEFAEAGNRVYLPI 585
>gi|336177350|ref|YP_004582725.1| phosphomethylpyrimidine synthase [Frankia symbiont of Datisca
glomerata]
gi|334858330|gb|AEH08804.1| Phosphomethylpyrimidine synthase [Frankia symbiont of Datisca
glomerata]
Length=614
Score = 791 bits (2044), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 400/573 (70%), Positives = 443/573 (78%), Gaps = 43/573 (7%)
Query 9 VTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTA 68
VT+GP+ GS K Y GS L+VP R V LSTGD LYDTSGPYTDT+ V D+
Sbjct 50 VTSGPLPGSRKTYLV----GSADGLRVPMREVLLSTGDSVILYDTSGPYTDTEQVTDVRQ 105
Query 69 GLPH-RPGVVRDRG--------------------------------TQLQRARAGEITAE 95
GLP R + RG TQL AR GEIT E
Sbjct 106 GLPPLRDAWITARGDTETYQNASPQVRHGERLRRPSPRRALPGRAVTQLAYARRGEITPE 165
Query 96 MAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSS 155
M F+A RE + E VR E+A GRAV+PAN +HPESEPM IG A VK+NANIGNSAVTSS
Sbjct 166 MEFVALREGLPVETVRAEIAAGRAVLPANVNHPESEPMAIGSALLVKINANIGNSAVTSS 225
Query 156 IAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPT 215
I EEVDKMVWATRWGADT+MDLSTG++IH TREWI+RNSPVP+GTVPIYQALEKV G
Sbjct 226 IEEEVDKMVWATRWGADTVMDLSTGRDIHTTREWIIRNSPVPIGTVPIYQALEKVGGKAE 285
Query 216 ELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHR 275
EL+WE+YRDTVIEQCEQGVDYMTVHAGVLLRYVPLTA+R TGIVSRGGSI+AAWCLAHH+
Sbjct 286 ELSWEVYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTARRKTGIVSRGGSILAAWCLAHHQ 345
Query 276 ESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKAHGA 335
E+FLYT+F ELC+I YDVTFSLGDGLRPGSIADANDAAQ AEL TLGELT +A H
Sbjct 346 ENFLYTHFAELCEILRAYDVTFSLGDGLRPGSIADANDAAQLAELATLGELTSVAWEHDV 405
Query 336 QVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQA 395
QVMIEGPGH+PM+KI ENV L+ ELC +APFYTLGPL TDIAP YDHITSAIGAA+I
Sbjct 406 QVMIEGPGHVPMNKIKENVDLQRELCHDAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWY 465
Query 396 GTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFR 455
GTAMLCYVTPKEHLGLPDR DVK GVIAYKIAAHAADLAKGHP AQ DDALS ARF+FR
Sbjct 466 GTAMLCYVTPKEHLGLPDRDDVKAGVIAYKIAAHAADLAKGHPGAQAWDDALSDARFDFR 525
Query 456 WNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVREYAAEHGL-E 514
W DQF L+LDP+TA+ FHDETLPA PAK+AHFCSMCGP FCSMRITQDVR+YA EHG+ E
Sbjct 526 WTDQFHLALDPETAKAFHDETLPAAPAKSAHFCSMCGPHFCSMRITQDVRKYAEEHGIAE 585
Query 515 TEADIEAVLAAGMAEKSREFAEHGNRVYLPITQ 547
T+A + AG+ EKS EFA G+ VYLPI +
Sbjct 586 TDA-----VEAGLREKSAEFAARGSHVYLPIAE 613
Lambda K H
0.318 0.133 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 1210654467756
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40