BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0433 Length=376 Score E Sequences producing significant alignments: (Bits) Value gi|15839820|ref|NP_334857.1| carboxylate-amine ligase [Mycobacte... 774 0.0 gi|308376393|ref|ZP_07438698.2| hypothetical protein TMHG_03447 ... 773 0.0 gi|15607574|ref|NP_214947.1| carboxylate-amine ligase [Mycobacte... 771 0.0 gi|340625458|ref|YP_004743910.1| hypothetical protein MCAN_04311... 770 0.0 gi|298523910|ref|ZP_07011319.1| carboxylate-amine ligase [Mycoba... 769 0.0 gi|339297126|gb|AEJ49236.1| carboxylate-amine ligase [Mycobacter... 730 0.0 gi|240168908|ref|ZP_04747567.1| carboxylate-amine ligase [Mycoba... 703 0.0 gi|183980772|ref|YP_001849063.1| hypothetical protein MMAR_0748 ... 680 0.0 gi|62899760|sp|Q73T00.2|CAAL_MYCPA RecName: Full=Carboxylate-ami... 679 0.0 gi|118462492|ref|YP_883848.1| carboxylate-amine ligase [Mycobact... 678 0.0 gi|41410020|ref|NP_962856.1| carboxylate-amine ligase [Mycobacte... 677 0.0 gi|118617064|ref|YP_905396.1| carboxylate-amine ligase [Mycobact... 677 0.0 gi|254777160|ref|ZP_05218676.1| carboxylate-amine ligase [Mycoba... 677 0.0 gi|296167944|ref|ZP_06850088.1| carboxylate-amine ligase [Mycoba... 677 0.0 gi|254818945|ref|ZP_05223946.1| carboxylate-amine ligase [Mycoba... 674 0.0 gi|342859076|ref|ZP_08715730.1| carboxylate-amine ligase [Mycoba... 667 0.0 gi|126433175|ref|YP_001068866.1| carboxylate-amine ligase [Mycob... 647 0.0 gi|108797553|ref|YP_637750.1| carboxylate-amine ligase [Mycobact... 647 0.0 gi|145220776|ref|YP_001131454.1| carboxylate-amine ligase [Mycob... 646 0.0 gi|120401751|ref|YP_951580.1| carboxylate-amine ligase [Mycobact... 644 0.0 gi|118471684|ref|YP_885240.1| carboxylate-amine ligase [Mycobact... 639 0.0 gi|333989047|ref|YP_004521661.1| carboxylate-amine ligase [Mycob... 627 1e-177 gi|169631261|ref|YP_001704910.1| carboxylate-amine ligase [Mycob... 606 2e-171 gi|262200675|ref|YP_003271883.1| glutamate--cysteine ligase [Gor... 520 2e-145 gi|326383415|ref|ZP_08205102.1| carboxylate-amine ligase [Gordon... 515 4e-144 gi|296393251|ref|YP_003658135.1| glutamate--cysteine ligase [Seg... 513 1e-143 gi|343925511|ref|ZP_08765030.1| putative carboxylate-amine ligas... 513 1e-143 gi|317506342|ref|ZP_07964154.1| glutamate-cysteine ligase family... 510 1e-142 gi|296141401|ref|YP_003648644.1| glutamate--cysteine ligase [Tsu... 491 7e-137 gi|54027271|ref|YP_121513.1| carboxylate-amine ligase [Nocardia ... 491 9e-137 gi|312141210|ref|YP_004008546.1| carboxylate-amine ligase [Rhodo... 489 3e-136 gi|119717924|ref|YP_924889.1| carboxylate-amine ligase [Nocardio... 489 3e-136 gi|226361302|ref|YP_002779080.1| carboxylate-amine ligase [Rhodo... 488 5e-136 gi|111019165|ref|YP_702137.1| carboxylate-amine ligase [Rhodococ... 480 2e-133 gi|226304985|ref|YP_002764943.1| carboxylate-amine ligase [Rhodo... 477 1e-132 gi|326333161|ref|ZP_08199409.1| carboxylate-amine ligase [Nocard... 477 1e-132 gi|302525588|ref|ZP_07277930.1| carboxylate-amine ligase [Strept... 472 4e-131 gi|116671437|ref|YP_832370.1| carboxylate-amine ligase [Arthroba... 469 3e-130 gi|300784361|ref|YP_003764652.1| carboxylate-amine ligase [Amyco... 466 4e-129 gi|325964083|ref|YP_004241989.1| hypothetical protein Asphe3_273... 465 4e-129 gi|152968027|ref|YP_001363811.1| carboxylate-amine ligase [Kineo... 465 7e-129 gi|333918229|ref|YP_004491810.1| carboxylate-amine ligase [Amyco... 462 3e-128 gi|220913346|ref|YP_002488655.1| carboxylate-amine ligase [Arthr... 456 3e-126 gi|119963228|ref|YP_948590.1| carboxylate-amine ligase [Arthroba... 451 1e-124 gi|229821541|ref|YP_002883067.1| glutamate--cysteine ligase GCS2... 435 5e-120 gi|256831873|ref|YP_003160600.1| glutamate--cysteine ligase GCS2... 433 2e-119 gi|311743072|ref|ZP_07716880.1| carboxylate-amine ligase [Aeromi... 433 2e-119 gi|184200315|ref|YP_001854522.1| carboxylate-amine ligase [Kocur... 426 3e-117 gi|334336241|ref|YP_004541393.1| carboxylate-amine ligase ybdK [... 422 5e-116 gi|269796198|ref|YP_003315653.1| hypothetical protein Sked_29170... 420 2e-115 >gi|15839820|ref|NP_334857.1| carboxylate-amine ligase [Mycobacterium tuberculosis CDC1551] gi|254230783|ref|ZP_04924110.1| conserved hypothetical protein [Mycobacterium tuberculosis C] gi|308378632|ref|ZP_07483294.2| hypothetical protein TMJG_02170 [Mycobacterium tuberculosis SUMu010] gi|13879952|gb|AAK44671.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551] gi|124599842|gb|EAY58852.1| conserved hypothetical protein [Mycobacterium tuberculosis C] gi|308359754|gb|EFP48605.1| hypothetical protein TMJG_02170 [Mycobacterium tuberculosis SUMu010] gi|323721105|gb|EGB30167.1| hypothetical protein TMMG_03192 [Mycobacterium tuberculosis CDC1551A] Length=383 Score = 774 bits (1999), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/376 (100%), Positives = 376/376 (100%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 8 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 67 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA Sbjct 68 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 127 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG Sbjct 128 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 187 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE Sbjct 188 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 247 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV Sbjct 248 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 307 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD Sbjct 308 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 367 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAELVI Sbjct 368 GDLRAVVDALVAELVI 383 >gi|308376393|ref|ZP_07438698.2| hypothetical protein TMHG_03447 [Mycobacterium tuberculosis SUMu008] gi|308351181|gb|EFP40032.1| hypothetical protein TMHG_03447 [Mycobacterium tuberculosis SUMu008] Length=381 Score = 773 bits (1995), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/376 (100%), Positives = 376/376 (100%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 6 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 65 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA Sbjct 66 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 125 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG Sbjct 126 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 185 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE Sbjct 186 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 245 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV Sbjct 246 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 305 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD Sbjct 306 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 365 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAELVI Sbjct 366 GDLRAVVDALVAELVI 381 >gi|15607574|ref|NP_214947.1| carboxylate-amine ligase [Mycobacterium tuberculosis H37Rv] gi|31791611|ref|NP_854104.1| carboxylate-amine ligase [Mycobacterium bovis AF2122/97] gi|121636347|ref|YP_976570.1| carboxylate-amine ligase [Mycobacterium bovis BCG str. Pasteur 1173P2] 69 more sequence titles Length=376 Score = 771 bits (1992), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/376 (99%), Positives = 376/376 (100%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA Sbjct 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE Sbjct 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV Sbjct 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD Sbjct 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAELVI Sbjct 361 GDLRAVVDALVAELVI 376 >gi|340625458|ref|YP_004743910.1| hypothetical protein MCAN_04311 [Mycobacterium canettii CIPT 140010059] gi|340003648|emb|CCC42771.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059] Length=376 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/376 (99%), Positives = 376/376 (100%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARRSAARIDFAGSPRPTLGVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPARRSAARIDFAGSPRPTLGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA Sbjct 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE Sbjct 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV Sbjct 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD Sbjct 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAELVI Sbjct 361 GDLRAVVDALVAELVI 376 >gi|298523910|ref|ZP_07011319.1| carboxylate-amine ligase [Mycobacterium tuberculosis 94_M4241A] gi|298493704|gb|EFI28998.1| carboxylate-amine ligase [Mycobacterium tuberculosis 94_M4241A] Length=376 Score = 769 bits (1985), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/376 (99%), Positives = 375/376 (99%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARRSAARID AGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPARRSAARIDCAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA Sbjct 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE Sbjct 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV Sbjct 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD Sbjct 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAELVI Sbjct 361 GDLRAVVDALVAELVI 376 >gi|339297126|gb|AEJ49236.1| carboxylate-amine ligase [Mycobacterium tuberculosis CCDC5180] Length=355 Score = 730 bits (1884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/355 (99%), Positives = 355/355 (100%), Gaps = 0/355 (0%) Query 22 VEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGICECTAEAMQDLRD 81 +EWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGICECTAEAMQDLRD Sbjct 1 MEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGICECTAEAMQDLRD 60 Query 82 TLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWWGRQMLIWGVHVH 141 TLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWWGRQMLIWGVHVH Sbjct 61 TLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWWGRQMLIWGVHVH 120 Query 142 VGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFHF 201 VGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFHF Sbjct 121 VGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFHF 180 Query 202 QRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSNLRELGALVALTH 261 QRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSNLRELGALVALTH Sbjct 181 QRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSNLRELGALVALTH 240 Query 262 CLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNERLVTDDLADVLT 321 CLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNERLVTDDLADVLT Sbjct 241 CLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNERLVTDDLADVLT 300 Query 322 RLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDALVAELVI 376 RLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDALVAELVI Sbjct 301 RLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDALVAELVI 355 >gi|240168908|ref|ZP_04747567.1| carboxylate-amine ligase [Mycobacterium kansasii ATCC 12478] Length=396 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/373 (91%), Positives = 355/373 (96%), Gaps = 0/373 (0%) Query 4 RRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVE 63 ++ RIDFA SPRPT+GVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRNTVE Sbjct 24 KKGDVRIDFAPSPRPTVGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRNTVE 83 Query 64 IVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELI 123 +VSGICEC AEAM DLRDTLG AR+IVRDRGMELFCAGTHPFARWS QKLTDAPRYAELI Sbjct 84 VVSGICECAAEAMDDLRDTLGSARRIVRDRGMELFCAGTHPFARWSTQKLTDAPRYAELI 143 Query 124 KRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYAS 183 KRTQWWGRQMLIWGVHVHVGI SA+KVMPI++SLLNYYPHLLALSASSPWWGGEDTGYAS Sbjct 144 KRTQWWGRQMLIWGVHVHVGISSANKVMPIISSLLNYYPHLLALSASSPWWGGEDTGYAS 203 Query 184 NRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRI 243 NRAMMFQQLPTAGLPF FQ WAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGT+E+R+ Sbjct 204 NRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTIEIRV 263 Query 244 CDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL 303 CDG+SNLRELGALVA THCL+VDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL Sbjct 264 CDGISNLRELGALVAFTHCLVVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL 323 Query 304 DADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDL 363 DADSNERLVT+DL D+LTRLEPVAKSLNCADELAAV++I R GASYQRQ RVA+ HDGDL Sbjct 324 DADSNERLVTEDLNDLLTRLEPVAKSLNCADELAAVAEIPRVGASYQRQRRVAEDHDGDL 383 Query 364 RAVVDALVAELVI 376 RAVVDALVAEL I Sbjct 384 RAVVDALVAELDI 396 >gi|183980772|ref|YP_001849063.1| hypothetical protein MMAR_0748 [Mycobacterium marinum M] gi|183174098|gb|ACC39208.1| conserved hypothetical protein [Mycobacterium marinum M] Length=383 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/372 (88%), Positives = 353/372 (95%), Gaps = 0/372 (0%) Query 5 RSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEI 64 R+A RIDFA SPRPT+GVEWEFALVD++TRDLSNEATAVIAEIGENPRVHKELLRNTVE+ Sbjct 12 RTANRIDFARSPRPTVGVEWEFALVDAETRDLSNEATAVIAEIGENPRVHKELLRNTVEV 71 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 VSG+C EA++DLR TLGPAR+IV RGMELFCAGTHPFA+WS QKLTDAPRYAELIK Sbjct 72 VSGVCGSAGEAIEDLRTTLGPARRIVHARGMELFCAGTHPFAQWSTQKLTDAPRYAELIK 131 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ SA+KVMPI+++LLNYYPHLLALSASSPWWGGEDTGYASN Sbjct 132 RTQWWGRQMLIWGVHVHVGVSSANKVMPIISALLNYYPHLLALSASSPWWGGEDTGYASN 191 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RAMMFQQLPTAGLPF FQ W+EFEGFVYDQKKTGIIDH++EIRWDIRPSPHLGT+E+RIC Sbjct 192 RAMMFQQLPTAGLPFQFQTWSEFEGFVYDQKKTGIIDHINEIRWDIRPSPHLGTIELRIC 251 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DGVSNLRELGALVAL HCL+VDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD Sbjct 252 DGVSNLRELGALVALMHCLVVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 311 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 A+SNERLVTDDL DVLTRLEPVA+SL+CADELAAV++I R GASYQRQ RVA++HDGDLR Sbjct 312 AESNERLVTDDLDDVLTRLEPVARSLSCADELAAVAEIPRVGASYQRQRRVAEEHDGDLR 371 Query 365 AVVDALVAELVI 376 AVVDAL+AEL I Sbjct 372 AVVDALIAELDI 383 >gi|62899760|sp|Q73T00.2|CAAL_MYCPA RecName: Full=Carboxylate-amine ligase MAP_3922 Length=376 Score = 679 bits (1751), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/376 (87%), Positives = 347/376 (93%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARR A IDFA SPRPT+GVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPARRGDAHIDFARSPRPTIGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+VSGIC EAM+DLR TLGPAR+IVRDRGMELFCAG HPFA+W+ QKLTDAPRYA Sbjct 61 TVEVVSGICRTVPEAMEDLRQTLGPARRIVRDRGMELFCAGAHPFAQWTTQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI S +KVMPIMTSLLNYYPHLLALSASSPWW G DTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ WAEFEGFVYDQKKTGIIDH+DE+RWDIRPSPHLGTLE Sbjct 181 YASNRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTLE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 +RICDGVSNL EL ALVALTHCL+VDLDRRL+A E+LPTMPPWH QENKWRAARYGLDAV Sbjct 241 MRICDGVSNLHELAALVALTHCLVVDLDRRLEADESLPTMPPWHHQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL DVL RLEPVA+ L CADELAAV+DI R GASYQRQ RVA++HD Sbjct 301 IILDADSNERLVTEDLDDVLNRLEPVARKLQCADELAAVADIPRHGASYQRQRRVAEEHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAEL I Sbjct 361 GDLRAVVDALVAELEI 376 >gi|118462492|ref|YP_883848.1| carboxylate-amine ligase [Mycobacterium avium 104] gi|148886815|sp|A0QLR0.1|CAAL_MYCA1 RecName: Full=Carboxylate-amine ligase MAV_4721 gi|118163779|gb|ABK64676.1| carboxylate-amine ligase [Mycobacterium avium 104] gi|336460336|gb|EGO39236.1| carboxylate-amine ligase, YbdK family [Mycobacterium avium subsp. paratuberculosis S397] Length=379 Score = 678 bits (1750), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/376 (87%), Positives = 347/376 (93%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARR A IDFA SPRPT+GVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 4 VPARRGDAHIDFARSPRPTIGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRN 63 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+VSGIC EAM+DLR TLGPAR+IVRDRGMELFCAG HPFA+W+ QKLTDAPRYA Sbjct 64 TVEVVSGICRTVPEAMEDLRQTLGPARRIVRDRGMELFCAGAHPFAQWTTQKLTDAPRYA 123 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI S +KVMPIMTSLLNYYPHLLALSASSPWW G DTG Sbjct 124 ELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTG 183 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ WAEFEGFVYDQKKTGIIDH+DE+RWDIRPSPHLGTLE Sbjct 184 YASNRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTLE 243 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 +RICDGVSNL EL ALVALTHCL+VDLDRRL+A E+LPTMPPWH QENKWRAARYGLDAV Sbjct 244 MRICDGVSNLHELAALVALTHCLVVDLDRRLEADESLPTMPPWHHQENKWRAARYGLDAV 303 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL DVL RLEPVA+ L CADELAAV+DI R GASYQRQ RVA++HD Sbjct 304 IILDADSNERLVTEDLDDVLNRLEPVARKLQCADELAAVADIPRHGASYQRQRRVAEEHD 363 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAEL I Sbjct 364 GDLRAVVDALVAELEI 379 >gi|41410020|ref|NP_962856.1| carboxylate-amine ligase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398853|gb|AAS06472.1| hypothetical protein MAP_3922 [Mycobacterium avium subsp. paratuberculosis K-10] Length=388 Score = 677 bits (1748), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/376 (87%), Positives = 347/376 (93%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARR A IDFA SPRPT+GVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 13 VPARRGDAHIDFARSPRPTIGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRN 72 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+VSGIC EAM+DLR TLGPAR+IVRDRGMELFCAG HPFA+W+ QKLTDAPRYA Sbjct 73 TVEVVSGICRTVPEAMEDLRQTLGPARRIVRDRGMELFCAGAHPFAQWTTQKLTDAPRYA 132 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI S +KVMPIMTSLLNYYPHLLALSASSPWW G DTG Sbjct 133 ELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTG 192 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ WAEFEGFVYDQKKTGIIDH+DE+RWDIRPSPHLGTLE Sbjct 193 YASNRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTLE 252 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 +RICDGVSNL EL ALVALTHCL+VDLDRRL+A E+LPTMPPWH QENKWRAARYGLDAV Sbjct 253 MRICDGVSNLHELAALVALTHCLVVDLDRRLEADESLPTMPPWHHQENKWRAARYGLDAV 312 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL DVL RLEPVA+ L CADELAAV+DI R GASYQRQ RVA++HD Sbjct 313 IILDADSNERLVTEDLDDVLNRLEPVARKLQCADELAAVADIPRHGASYQRQRRVAEEHD 372 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAEL I Sbjct 373 GDLRAVVDALVAELEI 388 >gi|118617064|ref|YP_905396.1| carboxylate-amine ligase [Mycobacterium ulcerans Agy99] gi|148886817|sp|A0PNK6.1|CAAL_MYCUA RecName: Full=Carboxylate-amine ligase MUL_1380 gi|118569174|gb|ABL03925.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99] Length=392 Score = 677 bits (1748), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/372 (87%), Positives = 352/372 (95%), Gaps = 0/372 (0%) Query 5 RSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEI 64 R+A RIDFA SPRPT+GVEWEFALVD++TRDLSNEATAVIAEIGENPRVHKELLRNTVE+ Sbjct 21 RTANRIDFARSPRPTVGVEWEFALVDAETRDLSNEATAVIAEIGENPRVHKELLRNTVEV 80 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 VSG+C EA++DLR TLGPAR+IV RGMELFC GTHPFA+WS QKLTDAPRYAELIK Sbjct 81 VSGVCGSAGEAIEDLRTTLGPARRIVHARGMELFCEGTHPFAQWSTQKLTDAPRYAELIK 140 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ SA+KVMPI+++LLNYYPHLLALSASSPWWGGEDTGYASN Sbjct 141 RTQWWGRQMLIWGVHVHVGVSSANKVMPIISALLNYYPHLLALSASSPWWGGEDTGYASN 200 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RAMMFQQLPTAGLPF FQ W+EFEGFVYDQKKTGIIDH++EIRWDIRPSPHLGT+E+RIC Sbjct 201 RAMMFQQLPTAGLPFQFQTWSEFEGFVYDQKKTGIIDHINEIRWDIRPSPHLGTIELRIC 260 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DGVSNLRELGALVAL HCL+VDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD Sbjct 261 DGVSNLRELGALVALMHCLVVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 320 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 A+SNERLVTDDL DVLTRLEPVA+SL+CADELAAV++I R GASYQRQ RVA++HDGDLR Sbjct 321 AESNERLVTDDLDDVLTRLEPVARSLSCADELAAVAEIPRVGASYQRQRRVAEEHDGDLR 380 Query 365 AVVDALVAELVI 376 AVVDAL+AEL I Sbjct 381 AVVDALIAELDI 392 >gi|254777160|ref|ZP_05218676.1| carboxylate-amine ligase [Mycobacterium avium subsp. avium ATCC 25291] Length=376 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/376 (87%), Positives = 347/376 (93%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PARR A IDFA SPRPT+GVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPARRGDAHIDFARSPRPTIGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+VSGIC EAM+DLR TLGPAR+IVRDRGMELFCAG HPFA+W+ QKLTDAPRYA Sbjct 61 TVEVVSGICRTVPEAMEDLRQTLGPARRIVRDRGMELFCAGAHPFAQWTTQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI S +KVMPIMTSLLNYYPHLLALSASSPWW G DTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ WAEFEGFVYDQKKTGIIDH+DE+RWDIRPSPHLGTLE Sbjct 181 YASNRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTLE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 +RICDGVSNL EL ALVALTHCL+VDLDRRL+A E+LPTMPPWH QENKWRAARYGLDAV Sbjct 241 MRICDGVSNLHELAALVALTHCLVVDLDRRLEADESLPTMPPWHHQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL DVL RLEPVA+ L CADELAAV+DI R GASYQRQ RVA++H+ Sbjct 301 IILDADSNERLVTEDLDDVLNRLEPVARKLQCADELAAVADIPRHGASYQRQRRVAEEHN 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAEL I Sbjct 361 GDLRAVVDALVAELEI 376 >gi|296167944|ref|ZP_06850088.1| carboxylate-amine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896934|gb|EFG76560.1| carboxylate-amine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=376 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/376 (87%), Positives = 346/376 (93%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PA R ARIDFA SPRPTLGVEWEFALVD++TRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPANRHNARIDFARSPRPTLGVEWEFALVDARTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+VSG+C EAM+DLR+TLGP +IVRDRGMELF AG HPFA+WS QKLTDAPRYA Sbjct 61 TVEVVSGVCRSAGEAMEDLRETLGPTHRIVRDRGMELFSAGAHPFAQWSTQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI SAHKVMPIMTSLL YYPHLLALSASSPWW G DTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGISSAHKVMPIMTSLLKYYPHLLALSASSPWWTGVDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ WAEFEGFVYDQKKTGIIDH+DE+RWDIRPSPHLGT+E Sbjct 181 YASNRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTIE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VR+CDGVSNLRELGALVALTHCL+VDLDRRL+A ETLPTMPPWH QENKWRAARYGLDA+ Sbjct 241 VRVCDGVSNLRELGALVALTHCLVVDLDRRLEADETLPTMPPWHNQENKWRAARYGLDAI 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 II DADSNERLVT+DL DVL RLEPVAKSL+C DELAAV+DI R GASYQRQ RVA++HD Sbjct 301 IIQDADSNERLVTEDLDDVLNRLEPVAKSLDCVDELAAVADIPRRGASYQRQRRVAEEHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALV EL I Sbjct 361 GDLRAVVDALVGELEI 376 >gi|254818945|ref|ZP_05223946.1| carboxylate-amine ligase [Mycobacterium intracellulare ATCC 13950] Length=376 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/376 (86%), Positives = 347/376 (93%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PA+R ARIDFA S RPT+GVEWEFALVD+QTRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPAKRRDARIDFARSSRPTIGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+V+GIC+ EAM+DLR TLGPAR+IVRDRGMELFCAG HPFA+W+ QKLT RYA Sbjct 61 TVEVVTGICQTAGEAMEDLRQTLGPARRIVRDRGMELFCAGAHPFAQWTTQKLTAGARYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI S +KVMPIMTSLLNYYPHLLALSASSPWW G DTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ W+EFEGFVYDQKKTGIIDH+DE+RWDIRPSPHLGTLE Sbjct 181 YASNRAMMFQQLPTAGLPFQFQTWSEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTLE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 +RICDGVSNLRELGALVALTHCL+VDLDRRL+A E+LP+MPPWH QENKWRAARYGLDAV Sbjct 241 MRICDGVSNLRELGALVALTHCLVVDLDRRLEADESLPSMPPWHNQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL DVL RLEPVAK LNC DELAAV++I R GASYQRQ RVA++HD Sbjct 301 IILDADSNERLVTEDLDDVLNRLEPVAKKLNCVDELAAVAEIPRQGASYQRQRRVAEEHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALV+EL I Sbjct 361 GDLRAVVDALVSELEI 376 >gi|342859076|ref|ZP_08715730.1| carboxylate-amine ligase [Mycobacterium colombiense CECT 3035] gi|342133317|gb|EGT86520.1| carboxylate-amine ligase [Mycobacterium colombiense CECT 3035] Length=376 Score = 667 bits (1720), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/376 (85%), Positives = 344/376 (92%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +PA IDFA S RPTLGVEWEFALVD+ TRDLSNEATAVIAEIGENPRVHKELLRN Sbjct 1 MPASGVNTHIDFARSARPTLGVEWEFALVDAHTRDLSNEATAVIAEIGENPRVHKELLRN 60 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+V+GIC EAM+DLR TLGPAR++VR+RGMELFCAG HPFA+W++QKLTDAPRYA Sbjct 61 TVEVVTGICSSAGEAMEDLRQTLGPARRVVRERGMELFCAGAHPFAQWTSQKLTDAPRYA 120 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQMLIWGVHVHVGI S +KVMPIMTSLLNYYPHLLALSASSPWW G DTG Sbjct 121 ELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTG 180 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF FQ WAEFE FVYDQKKTGIIDH+DE+RWDIRPSPHLGT+E Sbjct 181 YASNRAMMFQQLPTAGLPFQFQTWAEFERFVYDQKKTGIIDHVDEVRWDIRPSPHLGTIE 240 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 +RICDGVSNLRELGALVALTHCL+VDLDRRL+A E+LP+MPPWH QENKWRAARYGLDAV Sbjct 241 MRICDGVSNLRELGALVALTHCLVVDLDRRLEADESLPSMPPWHNQENKWRAARYGLDAV 300 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL DVL RLEPVA+ LNC DELAAV+DI R GASYQRQ RVA++HD Sbjct 301 IILDADSNERLVTEDLDDVLNRLEPVARKLNCVDELAAVADIPRQGASYQRQRRVAEEHD 360 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALVAEL I Sbjct 361 GDLRAVVDALVAELEI 376 >gi|126433175|ref|YP_001068866.1| carboxylate-amine ligase [Mycobacterium sp. JLS] gi|148886795|sp|A3PTZ8.1|CAAL1_MYCSJ RecName: Full=Carboxylate-amine ligase Mjls_0563 gi|126232975|gb|ABN96375.1| uncharacterized enzyme [Mycobacterium sp. JLS] Length=376 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/369 (84%), Positives = 337/369 (92%), Gaps = 0/369 (0%) Query 6 SAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIV 65 +++RIDFAGSPRPT+GVEWEFALVD+ TRDLSNEA VIAEIGE P VHKELLRNTVE+V Sbjct 6 ASSRIDFAGSPRPTVGVEWEFALVDAHTRDLSNEAATVIAEIGETPHVHKELLRNTVEVV 65 Query 66 SGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKR 125 +GICE T EAM DL DTL R+IVRDRGMELFCAGTHPFA WS Q+LTDAPRYAELIKR Sbjct 66 TGICENTGEAMADLHDTLQVVRRIVRDRGMELFCAGTHPFANWSTQQLTDAPRYAELIKR 125 Query 126 TQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNR 185 TQWWGRQMLIWGVHVHVGI SAHKVMPI++SLLN YPHLLALSASSP+W G DTGYASNR Sbjct 126 TQWWGRQMLIWGVHVHVGISSAHKVMPIISSLLNQYPHLLALSASSPYWDGSDTGYASNR 185 Query 186 AMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICD 245 AMMFQQLPTAGLPF FQ W EFE FV+DQKKTGIIDHM+EIRWDIRPSPHLGT+E+R+ D Sbjct 186 AMMFQQLPTAGLPFQFQSWPEFERFVHDQKKTGIIDHMNEIRWDIRPSPHLGTVEIRVFD 245 Query 246 GVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDA 305 GVSN+ ELG+LVALTHCL+VDLDRRLDAGE LP MPPWHVQENKWRAARYGLDA IILDA Sbjct 246 GVSNIAELGSLVALTHCLVVDLDRRLDAGEQLPVMPPWHVQENKWRAARYGLDAEIILDA 305 Query 306 DSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRA 365 DSNERLVT+DL D+LTRL+PVA+SL+CADELA V++IYR GASYQRQ RVA++HDGDL A Sbjct 306 DSNERLVTEDLDDLLTRLQPVARSLDCADELAGVAEIYRHGASYQRQRRVAEEHDGDLLA 365 Query 366 VVDALVAEL 374 VVDALVAEL Sbjct 366 VVDALVAEL 374 >gi|108797553|ref|YP_637750.1| carboxylate-amine ligase [Mycobacterium sp. MCS] gi|119866639|ref|YP_936591.1| carboxylate-amine ligase [Mycobacterium sp. KMS] gi|122977463|sp|Q1BEJ0.1|CAAL_MYCSS RecName: Full=Carboxylate-amine ligase Mmcs_0573 gi|148886796|sp|A1UAE3.1|CAAL1_MYCSK RecName: Full=Carboxylate-amine ligase Mkms_0585 gi|108767972|gb|ABG06694.1| Enzymatic protein of unknown function [Mycobacterium sp. MCS] gi|119692728|gb|ABL89801.1| uncharacterized enzyme [Mycobacterium sp. KMS] Length=376 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/369 (84%), Positives = 337/369 (92%), Gaps = 0/369 (0%) Query 6 SAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIV 65 +++RIDFAGSPRPT+GVEWEFALVD+ TRDLSNEA VIAEIGE P VHKELLRNTVE+V Sbjct 6 ASSRIDFAGSPRPTVGVEWEFALVDAHTRDLSNEAATVIAEIGETPHVHKELLRNTVEVV 65 Query 66 SGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKR 125 +GICE T EAM DL DTL R+IVRDRGMELFCAGTHPFA WS Q+LTDAPRYAELIKR Sbjct 66 TGICENTGEAMADLHDTLKVVRRIVRDRGMELFCAGTHPFANWSTQQLTDAPRYAELIKR 125 Query 126 TQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNR 185 TQWWGRQMLIWGVHVHVGI SAHKVMPI++SLLN YPHLLALSASSP+W G DTGYASNR Sbjct 126 TQWWGRQMLIWGVHVHVGISSAHKVMPIISSLLNQYPHLLALSASSPYWDGSDTGYASNR 185 Query 186 AMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICD 245 AMMFQQLPTAGLPF FQ W EFE FV+DQKKTGIIDHM+EIRWDIRPSPHLGT+E+R+ D Sbjct 186 AMMFQQLPTAGLPFQFQSWPEFERFVHDQKKTGIIDHMNEIRWDIRPSPHLGTVEIRVFD 245 Query 246 GVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDA 305 GVSN+ ELG+LVALTHCL+VDLDRRLDAGE LP MPPWHVQENKWRAARYGLDA IILDA Sbjct 246 GVSNIAELGSLVALTHCLVVDLDRRLDAGEQLPVMPPWHVQENKWRAARYGLDAEIILDA 305 Query 306 DSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRA 365 DSNERLVT+DL D+LTRL+PVA+SL+CADELA V++IYR GASYQRQ RVA++HDGDL A Sbjct 306 DSNERLVTEDLDDLLTRLQPVARSLDCADELAGVAEIYRHGASYQRQRRVAEEHDGDLLA 365 Query 366 VVDALVAEL 374 VVDALVAEL Sbjct 366 VVDALVAEL 374 >gi|145220776|ref|YP_001131454.1| carboxylate-amine ligase [Mycobacterium gilvum PYR-GCK] gi|315442270|ref|YP_004075149.1| enzyme [Mycobacterium sp. Spyr1] gi|145213262|gb|ABP42666.1| glutamate--cysteine ligase, GCS2 [Mycobacterium gilvum PYR-GCK] gi|315260573|gb|ADT97314.1| uncharacterized enzyme [Mycobacterium sp. Spyr1] Length=380 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/376 (83%), Positives = 342/376 (91%), Gaps = 0/376 (0%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN 60 +P +R +RIDF GS RPTLGVEWEFALVD+QTRDLSNEA +VIAEIGENPRVHKELLRN Sbjct 5 VPDQRPDSRIDFNGSVRPTLGVEWEFALVDAQTRDLSNEAASVIAEIGENPRVHKELLRN 64 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+V+GIC+ + +AM DL TL P R+IVR+RGMELFCAGTHPFA WSAQKLTDAPRYA Sbjct 65 TVEVVTGICDNSGQAMDDLASTLRPVREIVRERGMELFCAGTHPFADWSAQKLTDAPRYA 124 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELIKRTQWWGRQM IWGVHVHVG+ SAHKVMPI+TSLL+ YPHLLALSASSP+W GEDTG Sbjct 125 ELIKRTQWWGRQMTIWGVHVHVGVSSAHKVMPIITSLLHQYPHLLALSASSPFWDGEDTG 184 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPFHFQ W E+E FV DQKKTGIIDHM+EIRWDIRPSPHLGT+E Sbjct 185 YASNRAMMFQQLPTAGLPFHFQEWREWERFVSDQKKTGIIDHMNEIRWDIRPSPHLGTIE 244 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VRI DGVSNL EL ALVALTHCLIVDLDRR++AGE+LP MPPWHVQENKWRAARYGLDA+ Sbjct 245 VRIFDGVSNLHELSALVALTHCLIVDLDRRIEAGESLPVMPPWHVQENKWRAARYGLDAI 304 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 IILDADSNERLVT+DL D+L RL+PVA+ L+C DELA V DIY +GASYQRQ RVA++HD Sbjct 305 IILDADSNERLVTEDLDDLLERLQPVARKLDCVDELARVPDIYHNGASYQRQRRVAEEHD 364 Query 361 GDLRAVVDALVAELVI 376 GDLRAVVDALV+ELV+ Sbjct 365 GDLRAVVDALVSELVL 380 >gi|120401751|ref|YP_951580.1| carboxylate-amine ligase [Mycobacterium vanbaalenii PYR-1] gi|148886797|sp|A1T324.1|CAAL1_MYCVP RecName: Full=Carboxylate-amine ligase Mvan_0736 gi|119954569|gb|ABM11574.1| uncharacterized enzyme [Mycobacterium vanbaalenii PYR-1] Length=380 Score = 644 bits (1662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/373 (83%), Positives = 338/373 (91%), Gaps = 0/373 (0%) Query 4 RRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVE 63 +R+ RIDF GS RPT+GVEWEFALVD+ TRDLSNEA +VIAEIGENPRVHKELLRNTVE Sbjct 8 QRADGRIDFVGSVRPTVGVEWEFALVDATTRDLSNEAASVIAEIGENPRVHKELLRNTVE 67 Query 64 IVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELI 123 +V+GIC EAM+DL TL P R++VR+RGM+LFCAGTHPFA WS QKLTDAPRYAELI Sbjct 68 VVTGICANAGEAMEDLASTLRPVREVVRERGMDLFCAGTHPFADWSVQKLTDAPRYAELI 127 Query 124 KRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYAS 183 KRTQWWGRQMLIWGVHVHVG+ SAHKVMPI+T+LL+ YPHLLALSASSP+W GEDTGYAS Sbjct 128 KRTQWWGRQMLIWGVHVHVGVSSAHKVMPIITALLHQYPHLLALSASSPYWDGEDTGYAS 187 Query 184 NRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRI 243 NRAMMFQQLPTAGLPFHFQ W EFE FV DQKKTGIIDHM+EIRWDIRPSPHLGT+EVRI Sbjct 188 NRAMMFQQLPTAGLPFHFQEWREFERFVSDQKKTGIIDHMNEIRWDIRPSPHLGTIEVRI 247 Query 244 CDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL 303 DGVSNL EL ALVALTHCLIVDLDRRLDAGE+LP MPPWHVQENKWRAARYGLDA+IIL Sbjct 248 FDGVSNLHELSALVALTHCLIVDLDRRLDAGESLPVMPPWHVQENKWRAARYGLDAIIIL 307 Query 304 DADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDL 363 DADSNERLVT+DL D+L RL+PVAK L+C +EL+ V DIY +GASYQRQ RVA++HDGDL Sbjct 308 DADSNERLVTEDLDDLLERLQPVAKRLSCVEELSRVPDIYHNGASYQRQRRVAEEHDGDL 367 Query 364 RAVVDALVAELVI 376 RAVVDALV+ELV+ Sbjct 368 RAVVDALVSELVL 380 >gi|118471684|ref|YP_885240.1| carboxylate-amine ligase [Mycobacterium smegmatis str. MC2 155] gi|170652917|sp|A0QQQ2.1|CAAL1_MYCS2 RecName: Full=Carboxylate-amine ligase MSMEG_0836 gi|118172971|gb|ABK73867.1| carboxylate-amine ligase [Mycobacterium smegmatis str. MC2 155] Length=376 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/367 (84%), Positives = 332/367 (91%), Gaps = 0/367 (0%) Query 8 ARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSG 67 +RIDFAGSPRPT+GVEWEFALVD++TR+LSNEA AVIAEIGENP VHKELLRNTVEIV+G Sbjct 8 SRIDFAGSPRPTVGVEWEFALVDAKTRELSNEAAAVIAEIGENPHVHKELLRNTVEIVTG 67 Query 68 ICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQ 127 ICE + EAM DL DTL R+ VR RGMELFCAGTHPF +WSA +LTDAPRYAELIKRTQ Sbjct 68 ICENSGEAMGDLCDTLSTVRRAVRGRGMELFCAGTHPFGKWSAAQLTDAPRYAELIKRTQ 127 Query 128 WWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAM 187 WWGRQMLIWGVHVHVG+ SAHKVMPI++SLLN YPHLLALSASSP+W GEDTGYASNRAM Sbjct 128 WWGRQMLIWGVHVHVGVSSAHKVMPIISSLLNQYPHLLALSASSPFWDGEDTGYASNRAM 187 Query 188 MFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGV 247 MFQQLPTAGLPF FQ W EFEGFV+DQKKTGIIDH+ EIRWDIRPSP LGT+EVRI DGV Sbjct 188 MFQQLPTAGLPFQFQTWHEFEGFVHDQKKTGIIDHLSEIRWDIRPSPQLGTVEVRIFDGV 247 Query 248 SNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADS 307 SN+REL ALVALTHCLIVDLDRRLDAGE LP MPPWHVQENKWRAARYGLDAVIILDADS Sbjct 248 SNVRELSALVALTHCLIVDLDRRLDAGEQLPVMPPWHVQENKWRAARYGLDAVIILDADS 307 Query 308 NERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVV 367 NERLVT+DL D+L LEPVA SL+CADELAAV DIYR G SYQRQ RVA+++DGDLR VV Sbjct 308 NERLVTEDLDDLLNHLEPVAASLHCADELAAVEDIYRLGGSYQRQRRVAEENDGDLREVV 367 Query 368 DALVAEL 374 DAL+ EL Sbjct 368 DALIGEL 374 >gi|333989047|ref|YP_004521661.1| carboxylate-amine ligase [Mycobacterium sp. JDM601] gi|333485015|gb|AEF34407.1| carboxylate-amine ligase [Mycobacterium sp. JDM601] Length=356 Score = 627 bits (1616), Expect = 1e-177, Method: Compositional matrix adjust. Identities = 297/355 (84%), Positives = 328/355 (93%), Gaps = 0/355 (0%) Query 22 VEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGICECTAEAMQDLRD 81 +EWEFALVD+ TRDLSNEA+AV+AE+GENPRVH ELLRNTVE+V+GIC+ T EA++DLR Sbjct 1 MEWEFALVDAATRDLSNEASAVLAELGENPRVHNELLRNTVELVTGICDSTGEAIEDLRQ 60 Query 82 TLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWWGRQMLIWGVHVH 141 TL R IV RGMELF AGTHPFA+WSAQKLTDAPRYAELIKRTQWWGRQM+IWGVHVH Sbjct 61 TLAATRPIVHSRGMELFGAGTHPFAQWSAQKLTDAPRYAELIKRTQWWGRQMMIWGVHVH 120 Query 142 VGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFHF 201 VGI SA+KVMPI++SLL YYPHLLALSASSPWW GEDTGYASNRAMMFQQLPTAGLPF F Sbjct 121 VGISSAYKVMPIISSLLLYYPHLLALSASSPWWAGEDTGYASNRAMMFQQLPTAGLPFQF 180 Query 202 QRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSNLRELGALVALTH 261 Q W+EFEGFVYDQKKTGIIDH++EIRWDIRPSPHLGT+EVR+CDGVSNLRELG+LVALTH Sbjct 181 QTWSEFEGFVYDQKKTGIIDHINEIRWDIRPSPHLGTIEVRVCDGVSNLRELGSLVALTH 240 Query 262 CLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNERLVTDDLADVLT 321 CLIVDLDRRLDA ++LPTMPPWHVQENKWRAARYGLDA IILDADSNERLVT+DL ++L Sbjct 241 CLIVDLDRRLDADQSLPTMPPWHVQENKWRAARYGLDAEIILDADSNERLVTEDLDELLN 300 Query 322 RLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDALVAELVI 376 RLEP+A L+CADELA V+DIYR GASYQRQ RVA++HDGDLRAVVDALVAEL I Sbjct 301 RLEPIAARLHCADELAGVADIYRTGASYQRQRRVAEEHDGDLRAVVDALVAELDI 355 >gi|169631261|ref|YP_001704910.1| carboxylate-amine ligase [Mycobacterium abscessus ATCC 19977] gi|169243228|emb|CAM64256.1| Possible carboxylate-amine ligase [Mycobacterium abscessus] Length=378 Score = 606 bits (1563), Expect = 2e-171, Method: Compositional matrix adjust. Identities = 287/365 (79%), Positives = 321/365 (88%), Gaps = 0/365 (0%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGIC 69 I+F GSPRPTLGVEWEFALVD+QTRDL+N A+AV+A IGE P VHKELLRNT+E+V+GIC Sbjct 5 IEFRGSPRPTLGVEWEFALVDAQTRDLTNAASAVLAAIGETPHVHKELLRNTIEVVTGIC 64 Query 70 ECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWW 129 EAM DL+ TL R IV+ GMELFCAGTHPFARWSAQ+LTDAPRY ELI RTQWW Sbjct 65 GTVGEAMHDLQTTLATVRPIVQSMGMELFCAGTHPFARWSAQQLTDAPRYDELIARTQWW 124 Query 130 GRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMF 189 GRQMLIWGVHVHVGI S HKVMPI+TS+LNYYPHLLALSASSP W G+DTGYASNRAMMF Sbjct 125 GRQMLIWGVHVHVGISSKHKVMPIVTSMLNYYPHLLALSASSPMWEGQDTGYASNRAMMF 184 Query 190 QQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSN 249 QQLPTAGLPFHFQ W +FEGFV DQ KTGIID ++EIRWDIRPSP LGT+EVRI DG+SN Sbjct 185 QQLPTAGLPFHFQAWEQFEGFVDDQMKTGIIDQLNEIRWDIRPSPALGTVEVRIFDGISN 244 Query 250 LRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNE 309 + EL ALVALTHCL+VDLDR+L+AGE+LPTMPPWHVQENKWR+ARYGLDAVIILD DSNE Sbjct 245 VAELEALVALTHCLVVDLDRKLEAGESLPTMPPWHVQENKWRSARYGLDAVIILDEDSNE 304 Query 310 RLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDA 369 RLVT+DL D+LTRL+P+A+ L C ELAAV +IYR G SYQRQ RVA++HDGDL AVVDA Sbjct 305 RLVTEDLDDLLTRLQPIARLLECETELAAVEEIYRHGGSYQRQRRVAEEHDGDLGAVVDA 364 Query 370 LVAEL 374 +V EL Sbjct 365 VVNEL 369 >gi|262200675|ref|YP_003271883.1| glutamate--cysteine ligase [Gordonia bronchialis DSM 43247] gi|262084022|gb|ACY19990.1| glutamate--cysteine ligase GCS2 [Gordonia bronchialis DSM 43247] Length=379 Score = 520 bits (1338), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 252/374 (68%), Positives = 292/374 (79%), Gaps = 6/374 (1%) Query 6 SAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGEN-----PRVHKELLRN 60 S I F GSP P+LGVEWEFAL D Q+ DLSN A A+ A + + +VHKELLRN Sbjct 3 SIPSIPFRGSPTPSLGVEWEFALTDKQSGDLSNSAAALFAAVEQRHPEHAGQVHKELLRN 62 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+V+G+C TAEA+ DL TLG R I + G++L+ AGTHPFA WS Q LT+ RYA Sbjct 63 TVELVTGVCRTTAEALDDLSGTLGVVRGIADELGVDLYGAGTHPFAEWSTQLLTEGHRYA 122 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELI+RTQWWGRQMLIWGVHVHVGI KV+PI+ +LLNYYPHLLA+SASSP W G+DTG Sbjct 123 ELIERTQWWGRQMLIWGVHVHVGISHRDKVLPILDALLNYYPHLLAISASSPMWAGQDTG 182 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF F RW EFE FV DQK TGIIDH++EIRWDIRPSPHLGT+E Sbjct 183 YASNRAMMFQQLPTAGLPFQFARWDEFESFVADQKTTGIIDHLNEIRWDIRPSPHLGTIE 242 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VR+CDG++NLREL A VAL HCL+VDLDRRL+AGETLPTM PW VQENKWRAARYGLDA+ Sbjct 243 VRVCDGMTNLRELSAAVALIHCLVVDLDRRLEAGETLPTMAPWLVQENKWRAARYGLDAI 302 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 +I D + ERLVT+DLA VL RL P+A+ L+C DELA V+ I G SYQRQ R Sbjct 303 VITDGNCAERLVTEDLAGVLDRLAPIARDLDCIDELAGVTSIIESGGSYQRQ-RAVHAGG 361 Query 361 GDLRAVVDALVAEL 374 G +R VV ++V EL Sbjct 362 GTMRDVVASVVGEL 375 >gi|326383415|ref|ZP_08205102.1| carboxylate-amine ligase [Gordonia neofelifaecis NRRL B-59395] gi|326197821|gb|EGD55008.1| carboxylate-amine ligase [Gordonia neofelifaecis NRRL B-59395] Length=376 Score = 515 bits (1327), Expect = 4e-144, Method: Compositional matrix adjust. Identities = 252/374 (68%), Positives = 293/374 (79%), Gaps = 6/374 (1%) Query 6 SAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG-----ENPRVHKELLRN 60 S I F SP+PTLGVEWE ALVD +RDLSN A + + + ++H+ELLRN Sbjct 3 SPTEIAFTRSPKPTLGVEWELALVDKASRDLSNAADLLFELVDARAGDQRGKIHRELLRN 62 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+V+G+C +AM DL +L + + G++L+ AGTHPFA WS Q+L++ RYA Sbjct 63 TVELVTGVCTTVGQAMDDLGGSLEVVHALCDEIGIDLYGAGTHPFAEWSTQQLSEGHRYA 122 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 ELI+RTQWWGRQMLIWGVHVHVGI KV+PI++SLL YYPHLLALSASSP W G TG Sbjct 123 ELIERTQWWGRQMLIWGVHVHVGIDHRDKVLPILSSLLKYYPHLLALSASSPMWAGRATG 182 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YASNRAMMFQQLPTAGLPF F+ W+EFEGF DQK TGIIDH++EIRWDIRPSPHLGT+E Sbjct 183 YASNRAMMFQQLPTAGLPFQFESWSEFEGFARDQKTTGIIDHLNEIRWDIRPSPHLGTIE 242 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VR+CDGVSN REL A+VALTHCLIVDLDRRL AGETLP M PW VQENKWRAARYGLDA+ Sbjct 243 VRVCDGVSNRRELAAIVALTHCLIVDLDRRLTAGETLPQMAPWLVQENKWRAARYGLDAI 302 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 II DA +ERLVT+DLA++L RLEPVA SL C DELA V DI GASYQRQ V +Q Sbjct 303 IIQDAACSERLVTEDLAELLVRLEPVAASLGCLDELATVGDIVARGASYQRQQSVFEQ-T 361 Query 361 GDLRAVVDALVAEL 374 GD+R VVD++VAEL Sbjct 362 GDMRRVVDSVVAEL 375 >gi|296393251|ref|YP_003658135.1| glutamate--cysteine ligase [Segniliparus rotundus DSM 44985] gi|296180398|gb|ADG97304.1| glutamate--cysteine ligase GCS2 [Segniliparus rotundus DSM 44985] Length=388 Score = 513 bits (1322), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 247/375 (66%), Positives = 293/375 (79%), Gaps = 5/375 (1%) Query 5 RSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLR 59 R + FA S T+GVEWEFALV T+DL N A+AVI E+ G NP+VH+E LR Sbjct 9 RGRCPVPFASSAANTIGVEWEFALVHQDTKDLVNCASAVIDEVTVISDGVNPKVHREFLR 68 Query 60 NTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRY 119 NTVE V+G+C EAM+D+R+T+ + R + ELF AGTHPFA+WSAQ+ TDAPRY Sbjct 69 NTVEAVTGVCRTVGEAMEDIRETVAVLHKAARAQHAELFAAGTHPFAQWSAQQWTDAPRY 128 Query 120 AELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDT 179 EL+ RTQWWGRQMLIWGVHVHVG+ KV+PI++SLLN+YPHLLALSASSP W G DT Sbjct 129 HELMNRTQWWGRQMLIWGVHVHVGVDRREKVLPILSSLLNHYPHLLALSASSPLWSGVDT 188 Query 180 GYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTL 239 GYASNRAMMFQQLPTAGLPF F W EFE FV+DQ KTGII+H++EIRWDIRP+P GT+ Sbjct 189 GYASNRAMMFQQLPTAGLPFQFAEWREFEEFVFDQTKTGIIEHVNEIRWDIRPAPSHGTI 248 Query 240 EVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDA 299 EVRICDGVS +REL AL AL CL+ DL RLD GE LP+MPPWHVQENKWRAARYGLDA Sbjct 249 EVRICDGVSTVRELSALTALISCLVADLSERLDRGEALPSMPPWHVQENKWRAARYGLDA 308 Query 300 VIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQH 359 ++I+D SNERLVT+DL+D+L RL+P A+ L+CA+ELA V I G SYQRQ RVA++ Sbjct 309 IVIVDEQSNERLVTEDLSDLLERLQPQARKLDCAEELALVEQIPVLGGSYQRQRRVAERS 368 Query 360 DGDLRAVVDALVAEL 374 GD+RAVV A+V EL Sbjct 369 GGDMRAVVGAVVDEL 383 >gi|343925511|ref|ZP_08765030.1| putative carboxylate-amine ligase [Gordonia alkanivorans NBRC 16433] gi|343764603|dbj|GAA11956.1| putative carboxylate-amine ligase [Gordonia alkanivorans NBRC 16433] Length=373 Score = 513 bits (1322), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 248/370 (68%), Positives = 290/370 (79%), Gaps = 6/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGEN-----PRVHKELLRNTVEI 64 I+F GSP PTLGVEWEFAL D T DLSN A A+ A +GE+ ++HKELLRNTVE+ Sbjct 4 IEFDGSPTPTLGVEWEFALTDKVTGDLSNSAAALFAAVGEHHPDREGKIHKELLRNTVEL 63 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+GIC T EA+ DL DTLG R + + G++L+ AGTHPFA +S Q LT+ RYAELI+ Sbjct 64 VTGICRTTGEAIADLTDTLGVVRVLTEELGVDLYGAGTHPFAEYSTQLLTEGHRYAELIE 123 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVGI KV+PI+ SLLN+YPHLLALS+SSP W G+DTGYASN Sbjct 124 RTQWWGRQMLIWGVHVHVGISHRDKVLPILDSLLNFYPHLLALSSSSPMWAGQDTGYASN 183 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RAMMFQQLPTAGLPF F+ W +FE FV DQK TGIIDH++EIRWDIRPSPHLGT+EVR+C Sbjct 184 RAMMFQQLPTAGLPFQFETWDQFEAFVADQKTTGIIDHLNEIRWDIRPSPHLGTIEVRVC 243 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DG++NL EL A+VAL HCL+VDLDRR AGETLPTM PW VQENKWRAARYGLDA++ILD Sbjct 244 DGMTNLDELSAIVALIHCLVVDLDRRFSAGETLPTMAPWLVQENKWRAARYGLDAIVILD 303 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 E LVTDDL +L RL+P+A+ L C DELA V I GASYQRQ R + +R Sbjct 304 GQCREELVTDDLHRLLERLQPIARDLGCVDELAGVERIITQGASYQRQ-RAVYRDTHSMR 362 Query 365 AVVDALVAEL 374 VV ++VAEL Sbjct 363 DVVASVVAEL 372 >gi|317506342|ref|ZP_07964154.1| glutamate-cysteine ligase family 2(GCS2) [Segniliparus rugosus ATCC BAA-974] gi|316255352|gb|EFV14610.1| glutamate-cysteine ligase family 2(GCS2) [Segniliparus rugosus ATCC BAA-974] Length=388 Score = 510 bits (1314), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 245/370 (67%), Positives = 289/370 (79%), Gaps = 5/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLRNTVEI 64 + FA S TLGVEWEFALVD T+DL N A+AVI E+ G NP+VH+E LRNTVE+ Sbjct 14 VPFASSAANTLGVEWEFALVDQDTKDLVNCASAVIDEVTVISDGVNPKVHREFLRNTVEV 73 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+G+C EAM D+R T+ + + + ELF AGTHPFA+WSAQ+ TDAPRY EL+ Sbjct 74 VTGVCRTVGEAMDDIRQTVSVVSKAAQSQRAELFAAGTHPFAQWSAQQWTDAPRYHELMN 133 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ KV+PI++SLLN+YPHLLALSASSP W G DTGYASN Sbjct 134 RTQWWGRQMLIWGVHVHVGVDRREKVLPILSSLLNHYPHLLALSASSPLWSGVDTGYASN 193 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RAMMFQQLPTAGLPF F W EFE FV+DQ KTGII+ ++EIRWDIRP+P GT+EVRIC Sbjct 194 RAMMFQQLPTAGLPFQFAEWREFEEFVFDQTKTGIIEQVNEIRWDIRPAPSHGTIEVRIC 253 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DGVS LREL AL AL CL+ DL RLD GE LP++PPWHVQENKWRAARYGL+A++I+D Sbjct 254 DGVSTLRELSALTALICCLVADLGERLDRGEPLPSLPPWHVQENKWRAARYGLEAIVIVD 313 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 SNERLVT+DLAD+L RL P A+ L+C DEL++V I R G SYQRQ A++ DGDLR Sbjct 314 ERSNERLVTEDLADLLERLMPQARKLDCVDELSSVEQIPRLGGSYQRQRAAAERSDGDLR 373 Query 365 AVVDALVAEL 374 AVV +V EL Sbjct 374 AVVGTVVEEL 383 >gi|296141401|ref|YP_003648644.1| glutamate--cysteine ligase [Tsukamurella paurometabola DSM 20162] gi|296029535|gb|ADG80305.1| glutamate--cysteine ligase GCS2 [Tsukamurella paurometabola DSM 20162] Length=379 Score = 491 bits (1265), Expect = 7e-137, Method: Compositional matrix adjust. Identities = 238/352 (68%), Positives = 280/352 (80%), Gaps = 5/352 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGEN-----PRVHKELLRNTVEI 64 + F SPRPT+GVEWEFALVD +T DL + A + + + P+VH E+LRNTVE+ Sbjct 5 VAFRASPRPTIGVEWEFALVDRETADLVSRADELFDGVRDASEEIAPQVHSEMLRNTVEV 64 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+G+CE TAEAM DL TL R G++LF AGTHPFA+W+AQ+LTD PRY ELI Sbjct 65 VTGVCENTAEAMADLASTLTVVRGAADAMGVDLFGAGTHPFAQWNAQQLTDNPRYDELIA 124 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ KV+PI+++LLN YPHLLALSASSP WGG DTGYAS Sbjct 125 RTQWWGRQMLIWGVHVHVGVNHRDKVLPIISALLNQYPHLLALSASSPMWGGHDTGYAST 184 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RAMMFQQLPTAGLPF F++W+EFE FV+DQK TGIIDH++EIRWDIRP+ HLGT+EVR+C Sbjct 185 RAMMFQQLPTAGLPFQFEQWSEFERFVHDQKTTGIIDHLNEIRWDIRPACHLGTIEVRVC 244 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DG+S EL A+VAL HCL+V LD RLDAGE LPT+PPWHVQENKWRAARYGLDA+II D Sbjct 245 DGMSTFAELEAVVALIHCLVVWLDGRLDAGERLPTLPPWHVQENKWRAARYGLDAIIIQD 304 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVA 356 AD+NERLVT+DL D+L +L P+A+ L C EL AV DI R ASYQRQ VA Sbjct 305 ADNNERLVTEDLDDLLEQLTPIARGLGCERELRAVQDIPRRKASYQRQRAVA 356 >gi|54027271|ref|YP_121513.1| carboxylate-amine ligase [Nocardia farcinica IFM 10152] gi|62899841|sp|Q5YNU2.1|CAAL2_NOCFA RecName: Full=Carboxylate-amine ligase NFA_52970 gi|54018779|dbj|BAD60149.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=380 Score = 491 bits (1264), Expect = 9e-137, Method: Compositional matrix adjust. Identities = 236/371 (64%), Positives = 281/371 (76%), Gaps = 6/371 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGE------NPRVHKELLRNTVE 63 + F GSPRPT+G+EWE ALVD TRDLSN A AV +G+ P+V KELLRNTVE Sbjct 8 VPFEGSPRPTIGIEWEVALVDKVTRDLSNTAAAVFDAVGDLRAWDGTPQVTKELLRNTVE 67 Query 64 IVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELI 123 IV+G+ E A++DLR T+ R+ G+++FCAGTHPFA+WS Q+LT +P Y ELI Sbjct 68 IVTGVHETVGAAVEDLRGTMDKVRRAADPLGVDVFCAGTHPFAQWSTQQLTRSPHYDELI 127 Query 124 KRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYAS 183 +RTQWWGRQM+IWGVHVHVG+ KV PI+ SLL +PHLLALSASSP W G DTGYAS Sbjct 128 ERTQWWGRQMMIWGVHVHVGVSHREKVFPILNSLLTTFPHLLALSASSPMWAGSDTGYAS 187 Query 184 NRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRI 243 NR +MFQQLPTAGLPF F+ W +FE FV+D+ KTG+ + + + WDIRP+P GT+EVRI Sbjct 188 NRTLMFQQLPTAGLPFQFENWRQFEHFVHDELKTGVFEQLGGLHWDIRPAPKWGTIEVRI 247 Query 244 CDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL 303 CDG+ EL A+ A HCLIVDLD+R++ GE T+PPWHVQENKWRAARYGLDA++I Sbjct 248 CDGIPTHAELAAIAAFIHCLIVDLDQRIEDGEQPITLPPWHVQENKWRAARYGLDAIVIT 307 Query 304 DADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDL 363 DADSNERLVTDDL D+L RLEP AK L CADELA V+ I GASYQRQ +VA GDL Sbjct 308 DADSNERLVTDDLMDLLNRLEPTAKRLGCADELAYVATIPERGASYQRQRKVAAASQGDL 367 Query 364 RAVVDALVAEL 374 AVVDALV EL Sbjct 368 VAVVDALVHEL 378 >gi|312141210|ref|YP_004008546.1| carboxylate-amine ligase [Rhodococcus equi 103S] gi|325673960|ref|ZP_08153650.1| carboxylate-amine ligase [Rhodococcus equi ATCC 33707] gi|311890549|emb|CBH49867.1| carboxylate-amine ligase [Rhodococcus equi 103S] gi|325555225|gb|EGD24897.1| carboxylate-amine ligase [Rhodococcus equi ATCC 33707] Length=372 Score = 489 bits (1260), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 244/368 (67%), Positives = 286/368 (78%), Gaps = 3/368 (0%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG---ENPRVHKELLRNTVEIVS 66 + FAGSPRPT+GVEWE ALVD TRDLSN A V +G + PRV KELLRNTVE+V+ Sbjct 3 VPFAGSPRPTIGVEWEIALVDRTTRDLSNTAAEVFDAVGGLADEPRVTKELLRNTVELVT 62 Query 67 GICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRT 126 GIC+ EAM DL +T+ R+ G++L CAGTHPFA+WS Q +T P Y ELI+RT Sbjct 63 GICDNVGEAMDDLSETMSLVRRAADPLGVDLMCAGTHPFAQWSTQLITRTPHYDELIERT 122 Query 127 QWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRA 186 QWWGRQMLIWGVHVHVGI S KV PI+ +LL YPHLLALSASSP W G DTGYASNRA Sbjct 123 QWWGRQMLIWGVHVHVGISSKEKVFPILNALLLKYPHLLALSASSPMWTGVDTGYASNRA 182 Query 187 MMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDG 246 +MFQQLPTAGLPF F+ W +FEG+V DQ TG+I+++ + WDIRP+P GT+EVR+CDG Sbjct 183 LMFQQLPTAGLPFQFENWTQFEGYVDDQLTTGVIENLGGLHWDIRPAPRWGTIEVRVCDG 242 Query 247 VSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDAD 306 +S+ EL ALVAL HCL+V LD RL+AGETLP+MPPWHVQENKWRAARYG+DA +IL AD Sbjct 243 ISSRTELSALVALIHCLVVHLDERLEAGETLPSMPPWHVQENKWRAARYGIDAEVILGAD 302 Query 307 SNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAV 366 + ERLVTDDL D+L +L P A L CADELA V+DI R GASYQRQ +VA GDLRAV Sbjct 303 NRERLVTDDLDDLLEKLTPTAVRLGCADELARVADIPRRGASYQRQRKVAAATGGDLRAV 362 Query 367 VDALVAEL 374 V +LV EL Sbjct 363 VGSLVDEL 370 >gi|119717924|ref|YP_924889.1| carboxylate-amine ligase [Nocardioides sp. JS614] gi|148886808|sp|A1SN17.1|CAAL3_NOCSJ RecName: Full=Carboxylate-amine ligase Noca_3702 gi|119538585|gb|ABL83202.1| uncharacterized enzyme [Nocardioides sp. JS614] Length=376 Score = 489 bits (1259), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 239/370 (65%), Positives = 288/370 (78%), Gaps = 4/370 (1%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAE----IGENPRVHKELLRNTVEI 64 RIDF SP PTLGVEWEFALVD +TRDL N+AT + A + + ++HKELLRNTVE+ Sbjct 2 RIDFHASPEPTLGVEWEFALVDRRTRDLRNDATHLFARAKPRLPDPDKLHKELLRNTVEV 61 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 VSG+C EAM DLR TL D ++L+ GTHPFA W+ Q+L++ RY ELI Sbjct 62 VSGVCHTVGEAMADLRRTLEVVVPAGDDLDLDLYGGGTHPFASWTVQQLSEGHRYEELIN 121 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ +VM +++SLLN++PHL ALSASSP W G DTGYASN Sbjct 122 RTQWWGRQMLIWGVHVHVGMPERDRVMAVLSSLLNFHPHLQALSASSPIWSGIDTGYASN 181 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLPF F+RW+EFE FV D+ TG+I+ + E+RWD+RP+P +GTLE RIC Sbjct 182 RALMFQQLPTAGLPFQFERWSEFEAFVGDELVTGVIEELSEVRWDVRPAPRIGTLENRIC 241 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DGV +L +L +LVAL HCL+VDLD R AGETLPTMPPWHVQENKWRAARYGLDA++I D Sbjct 242 DGVPDLADLSSLVALMHCLVVDLDTRAAAGETLPTMPPWHVQENKWRAARYGLDAIVITD 301 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 A+SNERLVT+DLAD L RL PVA L C++ELA V+ I GASYQRQ VA++ GDL Sbjct 302 AESNERLVTEDLADHLERLAPVADRLGCSEELAQVAQIPVRGASYQRQRAVAERTGGDLV 361 Query 365 AVVDALVAEL 374 AVVD++V EL Sbjct 362 AVVDSVVREL 371 >gi|226361302|ref|YP_002779080.1| carboxylate-amine ligase [Rhodococcus opacus B4] gi|226239787|dbj|BAH50135.1| putative carboxylate-amine ligase [Rhodococcus opacus B4] Length=374 Score = 488 bits (1257), Expect = 5e-136, Method: Compositional matrix adjust. Identities = 240/370 (65%), Positives = 280/370 (76%), Gaps = 5/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG-----ENPRVHKELLRNTVEI 64 + F GSPRPTLGVEWE ALVD TRDLSN A V + E+PR+ KELLRNTVE+ Sbjct 3 VPFPGSPRPTLGVEWEIALVDRVTRDLSNTAAEVFDAVANLAGPEDPRITKELLRNTVEL 62 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+GI EAM DL ++L R+ G++L CAGTHPFA+WS Q +T P Y ELI+ Sbjct 63 VTGIHSTVGEAMDDLGESLDLLRRAANPLGVDLICAGTHPFAQWSTQLVTRTPDYDELIE 122 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ S KV PI+ +LL YPHLLALSASSP W G +TGYASN Sbjct 123 RTQWWGRQMLIWGVHVHVGVSSPQKVFPILNALLQRYPHLLALSASSPMWAGVNTGYASN 182 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLP+ F WA++E F+ DQ KTG+I + + WDIRP+P GT+EVR+ Sbjct 183 RALMFQQLPTAGLPYQFANWAQYEDFISDQMKTGVITKIGGMHWDIRPAPRWGTIEVRVF 242 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DG+S EL +LVAL HCLIVDLDRR +AGE LP + PWHV+ENKWRAARYGLDA IILD Sbjct 243 DGISTRAELSSLVALVHCLIVDLDRRFEAGENLPNLQPWHVKENKWRAARYGLDAEIILD 302 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 DSNERLVTDDL D+L +L P A L CADELAAV++I R GASYQRQ +VA+ GDL Sbjct 303 EDSNERLVTDDLNDLLEKLAPTAARLGCADELAAVAEIPRRGASYQRQRQVAEATGGDLV 362 Query 365 AVVDALVAEL 374 AVVDALV EL Sbjct 363 AVVDALVKEL 372 >gi|111019165|ref|YP_702137.1| carboxylate-amine ligase [Rhodococcus jostii RHA1] gi|118582160|sp|Q0SEQ7.1|CAAL2_RHOSR RecName: Full=Carboxylate-amine ligase RHA1_ro02172 gi|110818695|gb|ABG93979.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=374 Score = 480 bits (1235), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 239/370 (65%), Positives = 279/370 (76%), Gaps = 5/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG-----ENPRVHKELLRNTVEI 64 + F GSPRPTLGVEWE ALVD TRDLSN A V + E+PR+ KELLRNTVE+ Sbjct 3 VPFPGSPRPTLGVEWEIALVDRVTRDLSNTAAEVFDAVANLAGPEDPRITKELLRNTVEL 62 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+GI EAM DL ++L R+ G++L CAGTHPFA+WS Q +T P Y ELI+ Sbjct 63 VTGIHSTVGEAMDDLDESLDLLRRAANPLGVDLICAGTHPFAQWSTQLVTRTPDYDELIE 122 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ S KV PI+ +LL YPHLLALSASSP W G +TGYASN Sbjct 123 RTQWWGRQMLIWGVHVHVGVSSPQKVFPILNALLQRYPHLLALSASSPMWAGVNTGYASN 182 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLP+ F W ++E F+ DQ KTG+I + + WDIRP+P GT+EVR+ Sbjct 183 RALMFQQLPTAGLPYQFANWGQYEDFISDQMKTGVITKIGGMHWDIRPAPRWGTIEVRVF 242 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DG+S EL +LVAL HCLIVDLDRR +AGE LP + PWHV+ENKWRAARYGLDA IILD Sbjct 243 DGISTRAELSSLVALVHCLIVDLDRRFEAGENLPNLQPWHVKENKWRAARYGLDAEIILD 302 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 DSNERLVTDDL D+L +L P A L CADELAAV++I R GASYQRQ +VA+ GDL Sbjct 303 EDSNERLVTDDLNDLLEKLAPTAVRLGCADELAAVAEIPRRGASYQRQRQVAEATGGDLV 362 Query 365 AVVDALVAEL 374 AVVDALV EL Sbjct 363 AVVDALVKEL 372 >gi|226304985|ref|YP_002764943.1| carboxylate-amine ligase [Rhodococcus erythropolis PR4] gi|229493698|ref|ZP_04387482.1| carboxylate-amine ligase [Rhodococcus erythropolis SK121] gi|226184100|dbj|BAH32204.1| putative carboxylate-amine ligase [Rhodococcus erythropolis PR4] gi|229319367|gb|EEN85204.1| carboxylate-amine ligase [Rhodococcus erythropolis SK121] Length=374 Score = 477 bits (1228), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 246/370 (67%), Positives = 283/370 (77%), Gaps = 5/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLRNTVEI 64 + F GSPRPTLGVEWE ALVD +TRDLSN A V + + E P + KELLRNTVE+ Sbjct 3 VPFPGSPRPTLGVEWEIALVDRKTRDLSNTAAEVFSAVEELAGSETPHITKELLRNTVEL 62 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+GI EAM DL +L R+ G++L AGTHPFA+WS Q +T P Y ELI+ Sbjct 63 VTGIHSTVGEAMSDLDRSLDLLRRAANPLGVDLISAGTHPFAQWSTQLVTRTPDYDELIE 122 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ SA +V PI+ +LL YPHLLALSASSP W G DTGYASN Sbjct 123 RTQWWGRQMLIWGVHVHVGVSSADRVFPIINALLQRYPHLLALSASSPMWAGVDTGYASN 182 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLP+ F+ WAE+E F+ DQ KTG+I + + WDIRP+P GT+EVR+ Sbjct 183 RALMFQQLPTAGLPYQFENWAEYESFIDDQMKTGVITKIGGMHWDIRPAPKWGTIEVRVF 242 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DGVS ELGALVAL HCLIVDLDRRL AGETLP M PWHV+ENKWRAARYGLDA IILD Sbjct 243 DGVSTRAELGALVALVHCLIVDLDRRLSAGETLPNMQPWHVKENKWRAARYGLDAEIILD 302 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 +D+NE LVTDDL +L L P+A SL CADELA+V+DI R GASYQRQ RVA+ GDL Sbjct 303 SDANECLVTDDLDRLLDDLAPIAVSLGCADELASVADIPRRGASYQRQRRVAEATGGDLV 362 Query 365 AVVDALVAEL 374 AVVDALVAEL Sbjct 363 AVVDALVAEL 372 >gi|326333161|ref|ZP_08199409.1| carboxylate-amine ligase [Nocardioidaceae bacterium Broad-1] gi|325949052|gb|EGD41144.1| carboxylate-amine ligase [Nocardioidaceae bacterium Broad-1] Length=375 Score = 477 bits (1228), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 236/370 (64%), Positives = 277/370 (75%), Gaps = 4/370 (1%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGE---NP-RVHKELLRNTVEI 64 RIDF SPRPTLGVEWE ALVD Q+RDL N A + A NP R+HKELLRNTVEI Sbjct 2 RIDFHPSPRPTLGVEWELALVDRQSRDLVNVADHLFARAKARVPNPERIHKELLRNTVEI 61 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+GIC EA+ +R+T + D G++LF AGTHPFA W+ Q+L+ RY ELI Sbjct 62 VTGICGTVEEAIGQIRETTLEVVRAGDDLGVDLFGAGTHPFASWTRQELSAGHRYEELIN 121 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLIWGVHVHVG+ +V+P++ LL YYPH ALSASSP W G DTGYASN Sbjct 122 RTQWWGRQMLIWGVHVHVGMPERDRVLPVLNGLLTYYPHFQALSASSPIWAGVDTGYASN 181 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLPF F W EFE +V DQ TG+I+ + EIRWDIRPSP +GT+E RIC Sbjct 182 RALMFQQLPTAGLPFQFATWPEFEAYVSDQTVTGVIEDISEIRWDIRPSPRIGTIENRIC 241 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DGV+ L+EL A+ AL HCL VDLD R+ AGE + TMPPWHVQENKWRAARYGLDA++IL+ Sbjct 242 DGVATLQELAAIAALAHCLCVDLDARVAAGEPIATMPPWHVQENKWRAARYGLDAIVILN 301 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 S+ERLVT+DLAD+L RLEPVA L C ELA V DI GASYQRQ +A +GDL Sbjct 302 DASDERLVTEDLADLLVRLEPVAARLGCEKELAGVHDIIHKGASYQRQRAIAASTEGDLV 361 Query 365 AVVDALVAEL 374 AVVD++V +L Sbjct 362 AVVDSVVRDL 371 >gi|302525588|ref|ZP_07277930.1| carboxylate-amine ligase [Streptomyces sp. AA4] gi|302434483|gb|EFL06299.1| carboxylate-amine ligase [Streptomyces sp. AA4] Length=379 Score = 472 bits (1215), Expect = 4e-131, Method: Compositional matrix adjust. Identities = 224/371 (61%), Positives = 278/371 (75%), Gaps = 5/371 (1%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLRNTVE 63 RIDF S R T+G EWE ALVD ++ +L + A ++A + E+PR+ +ELL NT+E Sbjct 2 RIDFQASRRSTVGAEWELALVDRRSGELRSVAEELLAAVRPDGAPEHPRIKQELLLNTIE 61 Query 64 IVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELI 123 +VSG+C E DL + L ++ G+E+F AG+HPF+ W QK+TD RYA+LI Sbjct 62 VVSGVCRTVGEVKHDLAEALDEVHRVADPLGVEVFSAGSHPFSSWYRQKVTDKERYAKLI 121 Query 124 KRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYAS 183 RTQWWGRQMLI+GVHVHVG+ KV+P++ LL Y PHL ALSASSP+W GEDTGYAS Sbjct 122 DRTQWWGRQMLIYGVHVHVGLDHRDKVLPVLDGLLRYEPHLQALSASSPYWSGEDTGYAS 181 Query 184 NRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRI 243 NRA+MFQQLPTAGLPF F+ WAE EG+V D TG+IDH EIRWDIRP+PH GT+E+R+ Sbjct 182 NRALMFQQLPTAGLPFQFREWAELEGYVEDMFTTGVIDHFSEIRWDIRPAPHFGTIEMRV 241 Query 244 CDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL 303 CDG+ L+E+GA+ A T CL+ D RLD GETLP +PPWHVQENKWRAARYGLDA++IL Sbjct 242 CDGLPTLQEVGAISAFTQCLVDDFSARLDKGETLPALPPWHVQENKWRAARYGLDAIVIL 301 Query 304 DADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDL 363 DA ERLVT+DLADVL RLEPVAK L+C EL V +I + GASYQRQ VA+Q++G L Sbjct 302 DAAGRERLVTEDLADVLDRLEPVAKRLDCVRELRDVENILQVGASYQRQRAVAKQYNGSL 361 Query 364 RAVVDALVAEL 374 +AVV ALV E+ Sbjct 362 KAVVAALVTEM 372 >gi|116671437|ref|YP_832370.1| carboxylate-amine ligase [Arthrobacter sp. FB24] gi|148886794|sp|A0JZ00.1|CAAL1_ARTS2 RecName: Full=Carboxylate-amine ligase Arth_2891 gi|116611546|gb|ABK04270.1| uncharacterized enzyme [Arthrobacter sp. FB24] Length=383 Score = 469 bits (1207), Expect = 3e-130, Method: Compositional matrix adjust. Identities = 224/376 (60%), Positives = 280/376 (75%), Gaps = 10/376 (2%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVI----------AEIGENPRVHKELL 58 +IDFA S + TLGVEWE ALV++QT +L++ A V+ E E+P + +ELL Sbjct 2 KIDFASSRQSTLGVEWELALVNAQTGELASVANEVLRGVSANHPELNEDDEHPHIKQELL 61 Query 59 RNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPR 118 NTVE+V+GICE A+A DL +L R++ G+E+FCAG+HPF+ Q +TD R Sbjct 62 LNTVELVTGICETVAQAKADLSSSLAAVREVTDPMGVEVFCAGSHPFSPPQLQPVTDKAR 121 Query 119 YAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGED 178 YA+LI RTQWWGRQM+I+GVHVHVG+ S KV+P++ L+NY+PH ALSASSP+WGGED Sbjct 122 YAKLIDRTQWWGRQMVIYGVHVHVGLDSRDKVLPVLDGLVNYFPHFQALSASSPFWGGED 181 Query 179 TGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGT 238 TGYAS RA+MFQQLPTAGLPF F WAE+E +V D TG+ID + EIRWDIRP P+LGT Sbjct 182 TGYASQRALMFQQLPTAGLPFQFSTWAEYESYVQDMFTTGVIDTISEIRWDIRPVPNLGT 241 Query 239 LEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLD 298 +E+RICDG++ L E+GA+ ALT CL+ + LD G T+PTMPPWHVQENKWRAARYGL+ Sbjct 242 IEMRICDGLATLEEVGAIAALTQCLVDEFSTILDNGGTIPTMPPWHVQENKWRAARYGLE 301 Query 299 AVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQ 358 A+IILDA+ NE+LVTD L + L RLEPVA L C+DELA V I GA YQRQ RVA + Sbjct 302 AIIILDAEGNEQLVTDHLLETLNRLEPVAAKLGCSDELADVEKIISRGAGYQRQRRVAAE 361 Query 359 HDGDLRAVVDALVAEL 374 H GDLRAVV LV ++ Sbjct 362 HGGDLRAVVLDLVKQM 377 >gi|300784361|ref|YP_003764652.1| carboxylate-amine ligase [Amycolatopsis mediterranei U32] gi|299793875|gb|ADJ44250.1| carboxylate-amine ligase [Amycolatopsis mediterranei U32] gi|340525781|gb|AEK40986.1| carboxylate-amine ligase [Amycolatopsis mediterranei S699] Length=379 Score = 466 bits (1198), Expect = 4e-129, Method: Compositional matrix adjust. Identities = 220/370 (60%), Positives = 276/370 (75%), Gaps = 5/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLRNTVEI 64 I+F+ S R T+G EWE LVD ++ +LS+ A ++ + E+P++ +ELL NT+EI Sbjct 3 IEFSPSRRSTVGAEWELGLVDRRSGELSSVAEQILEAVRPDGQAEHPKIKQELLLNTIEI 62 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 ++G+C AEA DL D+L + G+E+F AGTHPF+ W QK+TD RYA+LI Sbjct 63 ITGVCGTIAEAKADLNDSLDVVHGVADPLGVEMFSAGTHPFSNWYQQKVTDKERYAKLID 122 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLI+GVH+HVG+ KV+P++ +LLNY PHL ALSASSP+WG EDTGYASN Sbjct 123 RTQWWGRQMLIYGVHIHVGVDHREKVLPVLDALLNYAPHLQALSASSPYWGAEDTGYASN 182 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLPF F++WAE E +V D TG+ID EIRWDIRPSP LGT+E+R+C Sbjct 183 RALMFQQLPTAGLPFQFRKWAELESYVEDMFTTGVIDSFSEIRWDIRPSPKLGTIEMRVC 242 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DG+ L E+GA+ ALT CL+ D RL+ GE LPT+PPWHVQENKWRAARYG DA++ILD Sbjct 243 DGLPTLEEVGAIAALTQCLVDDFVERLEDGEILPTLPPWHVQENKWRAARYGTDAIVILD 302 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 A ERLVTDD+AD+L RLEPVA+ L+C EL V I R G SY+RQ VAQQH G L+ Sbjct 303 AAGRERLVTDDVADLLDRLEPVARRLDCVAELRDVETILRYGPSYRRQRAVAQQHKGSLK 362 Query 365 AVVDALVAEL 374 AVV ALV E+ Sbjct 363 AVVAALVTEM 372 >gi|325964083|ref|YP_004241989.1| hypothetical protein Asphe3_27360 [Arthrobacter phenanthrenivorans Sphe3] gi|323470170|gb|ADX73855.1| uncharacterized enzyme [Arthrobacter phenanthrenivorans Sphe3] Length=383 Score = 465 bits (1197), Expect = 4e-129, Method: Compositional matrix adjust. Identities = 222/376 (60%), Positives = 278/376 (74%), Gaps = 10/376 (2%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG----------ENPRVHKELL 58 +IDFA S + TLGVEWE ALVD +T +L++ A V+ + E+P + +ELL Sbjct 2 KIDFASSRQSTLGVEWELALVDGRTGELASVANEVLRGVASRHPELNEDDEHPHIKQELL 61 Query 59 RNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPR 118 NTVE+V+GICE AEA +DL +L R+I G+ELFCAG+HPF+ Q +TD R Sbjct 62 LNTVELVTGICETAAEAKEDLSRSLAAVREITDPMGVELFCAGSHPFSPPQLQPVTDKAR 121 Query 119 YAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGED 178 YA+LI RTQWWGRQM+I+GVHVHVG+ S K +P++ L+NY+PH ALSASSP+WGGED Sbjct 122 YAKLIDRTQWWGRQMVIYGVHVHVGLDSRDKALPVLDGLVNYFPHFQALSASSPFWGGED 181 Query 179 TGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGT 238 TGYAS RA+MFQQLPTAGLPF F+ W E+E +V D TG+ID + EIRWDIRP P+LGT Sbjct 182 TGYASQRALMFQQLPTAGLPFQFRSWEEYESYVQDMFTTGVIDTLSEIRWDIRPVPNLGT 241 Query 239 LEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLD 298 +E+RICDG++ L E+GA+ ALT CL+ + LD G T+PTMPPWHVQENKWRAARYG+D Sbjct 242 IEMRICDGLATLEEVGAIAALTQCLVDEFSTTLDNGGTIPTMPPWHVQENKWRAARYGMD 301 Query 299 AVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQ 358 A+IILDA E+LVT+ L + L RLEPVAK L C DELA V I R GA YQRQ +VA + Sbjct 302 AIIILDASGKEQLVTEHLLETLNRLEPVAKKLGCPDELADVEKIIRRGAGYQRQRKVAAE 361 Query 359 HDGDLRAVVDALVAEL 374 H GDL+AVV LV ++ Sbjct 362 HGGDLQAVVLDLVKQM 377 >gi|152968027|ref|YP_001363811.1| carboxylate-amine ligase [Kineococcus radiotolerans SRS30216] gi|151362544|gb|ABS05547.1| glutamate--cysteine ligase GCS2 [Kineococcus radiotolerans SRS30216] Length=383 Score = 465 bits (1196), Expect = 7e-129, Method: Compositional matrix adjust. Identities = 230/382 (61%), Positives = 279/382 (74%), Gaps = 13/382 (3%) Query 3 ARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKEL 57 RRS ++F SPRPTLGVEWE LVD+ +RDL+ A V+A + PRV KEL Sbjct 2 GRRS---VEFNASPRPTLGVEWEMVLVDAASRDLAPRAAEVMAAVDREASATGPRVTKEL 58 Query 58 LRNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAP 117 LRNT+E+V+G+C+ AE +DL T+ R++ G++L AGTHPF RW Q +T Sbjct 59 LRNTLEVVTGVCDTVAEVAEDLTGTISAIRRVTDPMGLQLMSAGTHPFGRWDEQLVTPDE 118 Query 118 RYAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGE 177 RYAEL++RTQWWGRQMLIWGVHVHVG+ S HKV+PI+ +LLN+YPHL ALSASSP+W G Sbjct 119 RYAELLERTQWWGRQMLIWGVHVHVGVNSVHKVLPILNTLLNHYPHLQALSASSPYWTGF 178 Query 178 DTGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLG 237 DTGYASNRA MFQQLPTAGLPF F W EFE +V D TG+ID + ++RWDIRPSP G Sbjct 179 DTGYASNRAQMFQQLPTAGLPFQFGGWGEFEDYVDDMLVTGVIDGLSDVRWDIRPSPKFG 238 Query 238 TLEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGL 297 T+EVR+CDG LREL A+ AL HCL+V LD RL+AGE LPT+PPWHVQENKWRAARYGL Sbjct 239 TIEVRVCDGTPTLRELRAVTALIHCLVVHLDARLEAGEDLPTLPPWHVQENKWRAARYGL 298 Query 298 DAVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQ 357 DA II+DA ERLVTDDL + L RLEPVA+ L+CA++LA V+ I + GASYQRQ Sbjct 299 DAEIIVDAAGRERLVTDDLTEWLDRLEPVARRLDCAEDLALVAGIPQRGASYQRQRATFS 358 Query 358 QH-----DGDLRAVVDALVAEL 374 + L VVD+LV E+ Sbjct 359 RGCERGAPNPLHDVVDSLVQEM 380 >gi|333918229|ref|YP_004491810.1| carboxylate-amine ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333480450|gb|AEF39010.1| Carboxylate-amine ligase [Amycolicicoccus subflavus DQS3-9A1] Length=392 Score = 462 bits (1190), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 226/374 (61%), Positives = 275/374 (74%), Gaps = 10/374 (2%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGE---------NPRVHKELLRN 60 I F+GSPRPTLGVEWE A+V+ RDL N A AV+ ++ E + VHKE LRN Sbjct 3 IPFSGSPRPTLGVEWELAIVNRDDRDLVNAAEAVLEDLAERHGIDSTQASSPVHKEFLRN 62 Query 61 TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA 120 TVE+V+GIC EAM D+ +L G++ FCAG+HPFA W+ LTD P Y Sbjct 63 TVELVTGICNTVDEAMADISRSLKAVIAAGDRLGVDFFCAGSHPFAHWTDDMLTDKPNYV 122 Query 121 ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG 180 E+I R Q+WGRQ+LIWGVHVHVG+ A KV PI+ +LL YPHLLALS SSP W +DTG Sbjct 123 EIINRNQYWGRQLLIWGVHVHVGVSHADKVFPILNALLMKYPHLLALSGSSPIWDSKDTG 182 Query 181 YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE 240 YAS RA++FQQLPTAGLPF F+ W EFE F DQ KTGII+ + + WDIRP+P LGT+E Sbjct 183 YASTRALLFQQLPTAGLPFQFETWREFERFAGDQMKTGIIESLGGLHWDIRPAPSLGTIE 242 Query 241 VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV 300 VR+CDG+ LREL AL +L HCL+VDLDRRL+AGE LP+MPPW VQENKWRAARYGL+A Sbjct 243 VRVCDGIPTLRELAALTSLIHCLVVDLDRRLEAGEDLPSMPPWLVQENKWRAARYGLEAE 302 Query 301 IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD 360 +ILD + E+LVTDDL +L RLEP+A+ L CADELA V+DI R GASYQRQ R+A Q Sbjct 303 VILDRECREQLVTDDLTVMLERLEPIARHLECADELADVADIPRIGASYQRQRRIASQ-G 361 Query 361 GDLRAVVDALVAEL 374 G ++VD+LV+EL Sbjct 362 GSWASIVDSLVSEL 375 >gi|220913346|ref|YP_002488655.1| carboxylate-amine ligase [Arthrobacter chlorophenolicus A6] gi|219860224|gb|ACL40566.1| glutamate--cysteine ligase GCS2 [Arthrobacter chlorophenolicus A6] Length=383 Score = 456 bits (1173), Expect = 3e-126, Method: Compositional matrix adjust. Identities = 219/376 (59%), Positives = 276/376 (74%), Gaps = 10/376 (2%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG----------ENPRVHKELL 58 +IDFA S + TLGVEWE ALVD +T +L++ A V+ + E+P + +ELL Sbjct 2 KIDFAPSRQSTLGVEWELALVDGRTGELASVANEVLRGVASRHPELNEDDEHPHIKQELL 61 Query 59 RNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPR 118 NTVE+V+GICE AEA +DL ++ R+I G+ELFCAG+HPF+ Q +TD R Sbjct 62 LNTVELVTGICETAAEAKEDLSRSVAAVREITDPMGVELFCAGSHPFSPPQLQPVTDKAR 121 Query 119 YAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGED 178 YA+LI RTQWWGRQM+I+GVHVHVG+ K +P++ L+NY+PH ALSASSP+WGGED Sbjct 122 YAKLIDRTQWWGRQMVIYGVHVHVGLDRREKALPVLDGLVNYFPHFQALSASSPFWGGED 181 Query 179 TGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGT 238 TGYAS+RA+MFQQLPTAGLPF F W+E+E +V D TG+ID + EIRWDIRP P LGT Sbjct 182 TGYASHRALMFQQLPTAGLPFQFPSWSEYESYVQDMFTTGVIDTISEIRWDIRPVPALGT 241 Query 239 LEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLD 298 +E+RICDG++ L E+GA+ ALT CL+ + LD G T+PTMPPWHVQENKWRAARYG+D Sbjct 242 IEMRICDGLATLEEVGAIAALTQCLVDEFSTTLDNGGTIPTMPPWHVQENKWRAARYGMD 301 Query 299 AVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQ 358 A+IILDA E+LVTD L + L RLEPVA L C DELA V I R GA YQRQ RVA+ Sbjct 302 AIIILDAAGKEQLVTDHLLETLNRLEPVAAKLRCQDELADVEKIIRRGAGYQRQRRVAED 361 Query 359 HDGDLRAVVDALVAEL 374 + G+L+AVV LV ++ Sbjct 362 NGGNLQAVVLDLVKQM 377 >gi|119963228|ref|YP_948590.1| carboxylate-amine ligase [Arthrobacter aurescens TC1] gi|148886800|sp|A1R8M8.1|CAAL2_ARTAT RecName: Full=Carboxylate-amine ligase AAur_2882 gi|119950087|gb|ABM08998.1| putative glutamate-cysteine ligase family 2(GCS2) [Arthrobacter aurescens TC1] Length=383 Score = 451 bits (1159), Expect = 1e-124, Method: Compositional matrix adjust. Identities = 214/376 (57%), Positives = 281/376 (75%), Gaps = 10/376 (2%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG----------ENPRVHKELL 58 +IDFA S + TLGVEWE ALV+++T +L + A V+ + E+P + +ELL Sbjct 2 QIDFAPSRQSTLGVEWELALVNARTGELVSVANDVLKGVAANHPDLNEDDEHPHIKRELL 61 Query 59 RNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPR 118 NTVE+V+GICE +A +DL +L R++ G+E+FCAG+HPF+ Q +TD R Sbjct 62 LNTVELVTGICETVKDAKEDLSRSLAAVREVTDPMGVEVFCAGSHPFSPPLLQPVTDKER 121 Query 119 YAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGED 178 YA+LI+RTQWWGRQM+I+GVHVHVGI KV+PI+ L+NY+PH ALSASSP+W GE+ Sbjct 122 YAKLIERTQWWGRQMVIYGVHVHVGIDHRDKVLPILDGLVNYFPHFQALSASSPYWAGEE 181 Query 179 TGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGT 238 TGYAS RA+MFQQLPTAGLPF F+ W +E +V D TG+ID EIRWDIRP +LGT Sbjct 182 TGYASQRALMFQQLPTAGLPFQFETWEAYESYVQDMFTTGVIDATSEIRWDIRPVANLGT 241 Query 239 LEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLD 298 +E+RICDG++ L E+GA+ ALT CL+ + LDAG ++PTMPPWHVQENKWRAARYG++ Sbjct 242 IEMRICDGLATLEEVGAIAALTQCLVDEFSSILDAGGSIPTMPPWHVQENKWRAARYGME 301 Query 299 AVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQ 358 A+IILDA+ NE+LVT+ LA+ ++RLEPVA L C++ELA V I + GASYQRQ RVA + Sbjct 302 AIIILDAEGNEQLVTEHLAETVSRLEPVAAKLGCSEELADVLKIIQRGASYQRQRRVAAE 361 Query 359 HDGDLRAVVDALVAEL 374 H+GDL+AVV LV ++ Sbjct 362 HNGDLQAVVMDLVQQM 377 >gi|229821541|ref|YP_002883067.1| glutamate--cysteine ligase GCS2 [Beutenbergia cavernae DSM 12333] gi|229567454|gb|ACQ81305.1| glutamate--cysteine ligase GCS2 [Beutenbergia cavernae DSM 12333] Length=388 Score = 435 bits (1119), Expect = 5e-120, Method: Compositional matrix adjust. Identities = 219/379 (58%), Positives = 269/379 (71%), Gaps = 8/379 (2%) Query 1 LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHK 55 + ARR ++FA S R ++G+EWE ALVD+ + DL A V+ + E+P + + Sbjct 1 MAARRE---LEFAHSERSSVGIEWELALVDADSGDLRQVAQTVLDAVRPDGAEEHPLIKQ 57 Query 56 ELLRNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTD 115 ELL NTVE+VSG+ A+A +DL + R++ +EL CAG+HPFARW+ QK+T+ Sbjct 58 ELLLNTVEVVSGVQRTVADAGRDLERAIDAIREVTDPLRVELMCAGSHPFARWTQQKVTN 117 Query 116 APRYAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWG 175 RYA LI RTQWWGRQMLI+GVH HVGI KV+PI ++L PHL +LSASSP+WG Sbjct 118 KERYATLIDRTQWWGRQMLIYGVHTHVGIEDRSKVLPIARAMLTVAPHLQSLSASSPFWG 177 Query 176 GEDTGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPH 235 G+DTGYASNRA+MFQQLPTAGLPF F WAE E +V D TG+ID + EIRWDIRPSP Sbjct 178 GKDTGYASNRALMFQQLPTAGLPFAFTEWAELEQYVGDMLHTGVIDDVTEIRWDIRPSPR 237 Query 236 LGTLEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARY 295 LGTLEVR+CDG L EL AL A THCL+ LDAGE LP MPPW VQENKWR+ARY Sbjct 238 LGTLEVRVCDGTPTLGELLALSAFTHCLVEHFSSMLDAGEQLPAMPPWFVQENKWRSARY 297 Query 296 GLDAVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRV 355 G+DA++ILDAD +ERLVTD + D L LEPVA+ L C+ EL V I RDGASYQRQ Sbjct 298 GMDAILILDADGDERLVTDSVHDWLQVLEPVAERLGCSAELDDVRAILRDGASYQRQRAA 357 Query 356 AQQHDGDLRAVVDALVAEL 374 A++ G+L AVVD LV E+ Sbjct 358 AERAGGELDAVVDLLVREM 376 >gi|256831873|ref|YP_003160600.1| glutamate--cysteine ligase GCS2 [Jonesia denitrificans DSM 20603] gi|256685404|gb|ACV08297.1| glutamate--cysteine ligase GCS2 [Jonesia denitrificans DSM 20603] Length=379 Score = 433 bits (1114), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 207/370 (56%), Positives = 262/370 (71%), Gaps = 5/370 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLRNTVEI 64 I+F S R T+G+EWE ALVD + DL A ++ + G++P + +ELL NTVEI Sbjct 4 IEFQRSERSTIGIEWELALVDKDSGDLRQVAQTILDAVTPEGGGQHPHIRQELLLNTVEI 63 Query 65 VSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIK 124 V+G+C EA DL ++ R I +EL CAGTHPFARWS QK+TD RYA LI Sbjct 64 VTGVCRTVKEAGDDLALSIEQLRGITDPLRVELMCAGTHPFARWSNQKVTDKQRYATLID 123 Query 125 RTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASN 184 RTQWWGRQMLI+G+HVHVGI KV+PIM +++ Y+ H+ +LSASSP+WGG+DT YASN Sbjct 124 RTQWWGRQMLIYGIHVHVGIEDHRKVLPIMRAMMTYFGHMQSLSASSPFWGGKDTSYASN 183 Query 185 RAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRIC 244 RA+MFQQLPTAGLPF F W + E +V D K G+ID DE+RWD+RPSP GT+E RI Sbjct 184 RALMFQQLPTAGLPFQFDDWGQLEAYVDDMLKVGVIDQFDEVRWDLRPSPRYGTIETRIA 243 Query 245 DGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILD 304 DG SNL E+ AL ALT CL+ LD G+ LPTM PW +QENKWR+ARYG+DA++IL+ Sbjct 244 DGCSNLTEVLALAALTQCLVEHFSSLLDEGKPLPTMQPWFIQENKWRSARYGMDAILILN 303 Query 305 ADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLR 364 A +E LVT+DL ++T LEP A+ L C D+L + + R GASYQRQ VA++H GDL Sbjct 304 AQGDEELVTNDLPRLMTMLEPTAERLGCLDQLQHIDTMMRKGASYQRQRAVARRHGGDLG 363 Query 365 AVVDALVAEL 374 AVVD LV E+ Sbjct 364 AVVDHLVREM 373 >gi|311743072|ref|ZP_07716880.1| carboxylate-amine ligase [Aeromicrobium marinum DSM 15272] gi|311313752|gb|EFQ83661.1| carboxylate-amine ligase [Aeromicrobium marinum DSM 15272] Length=382 Score = 433 bits (1114), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 215/371 (58%), Positives = 259/371 (70%), Gaps = 5/371 (1%) Query 9 RIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEI-----GENPRVHKELLRNTVE 63 +I FA S R ++G+EWE ALVD+ + DL A V+ + G +P + +ELL NTVE Sbjct 2 QIPFATSERSSIGIEWELALVDADSGDLRQVAGYVLDAVAPPGGGPHPHIRQELLLNTVE 61 Query 64 IVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELI 123 +VSG+ EA +DL + R + +EL CAGTHPF+RW Q +TD RYA LI Sbjct 62 VVSGVASTVREAAEDLSRNVDLIRTVTDRLRVELMCAGTHPFSRWDMQHVTDKERYATLI 121 Query 124 KRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYAS 183 RTQWWGRQMLI+GVHVHVGI KV+PI ++L YY H ALSASSP+WGG+DTGYAS Sbjct 122 DRTQWWGRQMLIYGVHVHVGIEDRDKVLPISRAMLAYYGHFQALSASSPFWGGKDTGYAS 181 Query 184 NRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRI 243 NRA+MFQQLPTAGLPF F+RW+E EG+V D +TG+ID DEIRWD+RPSP GTLEVRI Sbjct 182 NRALMFQQLPTAGLPFQFERWSELEGYVADMMRTGVIDSFDEIRWDLRPSPKFGTLEVRI 241 Query 244 CDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIIL 303 CDG L E+ +L ALTHCL+ LDAG LPT+P W QENKWRAARYG+DA++IL Sbjct 242 CDGSPTLAEVKSLAALTHCLVEHFSAELDAGRPLPTIPAWFAQENKWRAARYGMDAILIL 301 Query 304 DADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDL 363 D D NE LVTDDL +L LEPVA+ L+C ELA + DI GASYQRQ VA G L Sbjct 302 DDDGNEDLVTDDLRRLLPVLEPVAERLDCTAELAGILDIVAAGASYQRQRAVAAASGGRL 361 Query 364 RAVVDALVAEL 374 VV LV E+ Sbjct 362 DVVVRHLVEEM 372 >gi|184200315|ref|YP_001854522.1| carboxylate-amine ligase [Kocuria rhizophila DC2201] gi|183580545|dbj|BAG29016.1| putative glutamate--cysteine ligase [Kocuria rhizophila DC2201] Length=393 Score = 426 bits (1095), Expect = 3e-117, Method: Compositional matrix adjust. Identities = 204/382 (54%), Positives = 266/382 (70%), Gaps = 10/382 (2%) Query 2 PARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVI----------AEIGENP 51 P A IDF S TLGVEWE ALVD ++ +L+ A V+ E G++P Sbjct 7 PREDHAVHIDFETSENSTLGVEWEVALVDRESGELAPRAQEVLEAVVGEYPELGEEGDHP 66 Query 52 RVHKELLRNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQ 111 +V E L+NTVE+V+G+C EA++ L T R+I R +E+F AGTHPF+ W+ Q Sbjct 67 QVTGEFLQNTVEMVTGVCSAVPEAVEHLAQTQDRIRKITDPRSLEIFAAGTHPFSDWTEQ 126 Query 112 KLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASS 171 + DA RY +++ R Q+WGRQM+I+G+HVHVGI K +P++ L+NYYPHLLALSA+S Sbjct 127 PVVDAERYYKVLDRAQYWGRQMVIFGMHVHVGIDHRDKALPVLDGLMNYYPHLLALSANS 186 Query 172 PWWGGEDTGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIR 231 P+W G DTGYAS+RA++FQQL TAGLPFHF W+E+E +V D +TG+I+ + E RWDIR Sbjct 187 PYWCGHDTGYASHRALIFQQLSTAGLPFHFDSWSEYEAYVSDLMETGVIEEISENRWDIR 246 Query 232 PSPHLGTLEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWR 291 P P GT+E+R+CDG SNLRE+GAL ALT CL+ R LD G ++ MPPWH QENKWR Sbjct 247 PVPRFGTVEMRVCDGPSNLREIGALAALTQCLVESFSRTLDEGRSIAVMPPWHHQENKWR 306 Query 292 AARYGLDAVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQR 351 AARYGLDAV+I DA ++ER V +DL +VL RLEP+A L CADEL V + YQR Sbjct 307 AARYGLDAVVIRDAQNHERPVAEDLTEVLNRLEPLAAELGCADELGYVETMMTGETGYQR 366 Query 352 QLRVAQQHDGDLRAVVDALVAE 373 Q R+A+ + GDLRAVV +VA+ Sbjct 367 QRRIAEANGGDLRAVVRDIVAQ 388 >gi|334336241|ref|YP_004541393.1| carboxylate-amine ligase ybdK [Isoptericola variabilis 225] gi|334106609|gb|AEG43499.1| Carboxylate-amine ligase ybdK [Isoptericola variabilis 225] Length=384 Score = 422 bits (1085), Expect = 5e-116, Method: Compositional matrix adjust. Identities = 207/371 (56%), Positives = 263/371 (71%), Gaps = 6/371 (1%) Query 10 IDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIG---ENPRVHKELLRNTVEIVS 66 ++FA S R T+G+EWE ALVD+ + +L A AVI +G + RV E LRNT+E++S Sbjct 3 LEFARSERSTVGLEWELALVDADSGNLRQVAPAVIDALGAELQEGRVKPEFLRNTIEVIS 62 Query 67 GICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRT 126 + EA++DL + + R + +EL CAGTHPFA WS QK+TD RY ++ R Sbjct 63 DVYRTVGEAVEDLEEGIAAIRAVTDPMRVELMCAGTHPFAHWSQQKVTDKRRYTTILDRA 122 Query 127 QWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRA 186 Q WGRQMLI+GVH+HVG+ KV+PI+ ++L Y PHL ALSASSP++G +DTGYAS RA Sbjct 123 QVWGRQMLIYGVHMHVGVEDRDKVLPIVNAMLVYVPHLQALSASSPFFGADDTGYASMRA 182 Query 187 MMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDG 246 ++FQQLPTAGLP+ F+ WAE E +V D +TG+ID +E+RWD+RP+P GT+EVR+CDG Sbjct 183 LLFQQLPTAGLPYQFRTWAELERYVDDMLRTGVIDEFNEVRWDVRPAPRFGTVEVRVCDG 242 Query 247 VSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDAD 306 VSN RELGAL AL HCL+ L R+DAGETLPTMPPW+V ENKWRAARYG+DA+IILD + Sbjct 243 VSNARELGALSALVHCLVEHLSTRIDAGETLPTMPPWYVHENKWRAARYGMDAIIILDDE 302 Query 307 SNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQ---LRVAQQHDGDL 363 E LVTD + +L LEPVA+ L CA EL V +I R GASYQRQ L Sbjct 303 GREELVTDAVERLLGELEPVAERLGCATELGHVREIVRTGASYQRQRAVAAAHGGGADGL 362 Query 364 RAVVDALVAEL 374 AVV +LVAEL Sbjct 363 EAVVASLVAEL 373 >gi|269796198|ref|YP_003315653.1| hypothetical protein Sked_29170 [Sanguibacter keddieii DSM 10542] gi|269098383|gb|ACZ22819.1| uncharacterized enzyme [Sanguibacter keddieii DSM 10542] Length=380 Score = 420 bits (1080), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 203/368 (56%), Positives = 257/368 (70%), Gaps = 5/368 (1%) Query 12 FAGSPRPTLGVEWEFALVDSQTRDLSNEATAVI-----AEIGENPRVHKELLRNTVEIVS 66 FA S R T+G+EWE ALVD + DL A V+ A+ ++P + +ELL NTVE+VS Sbjct 7 FAQSERSTVGIEWELALVDKDSGDLRQVAQTVLDAVAPADGSQHPHIRQELLLNTVEVVS 66 Query 67 GICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRT 126 G+ +A DL ++ R++ +EL AGTHPFARW+ QK+TD RYA LI RT Sbjct 67 GVSRTVRQAGDDLVRSMEEIREVTDPLRVELMSAGTHPFARWAQQKVTDKERYATLIDRT 126 Query 127 QWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRA 186 QWWGRQMLI+GVHVHVGI KV+PI ++L Y+ +LSASSP+WGG+DTGYASNRA Sbjct 127 QWWGRQMLIYGVHVHVGIEDRDKVLPISRAMLGYFGMFQSLSASSPFWGGKDTGYASNRA 186 Query 187 MMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDG 246 +MFQQLPTAGL F F+ W + EG+V D TG+ID DE+RWD+RPSP GTLE RICDG Sbjct 187 LMFQQLPTAGLGFQFEEWEQLEGYVADMMHTGVIDQFDEVRWDLRPSPRFGTLETRICDG 246 Query 247 VSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDAD 306 SN+ E+ A AL HCL+ L LD G+ LPT+ PW QENKWR+ARYG+DA++ILD Sbjct 247 ASNITEVLAFAALNHCLVEHLSTLLDQGKELPTIQPWFAQENKWRSARYGMDAIVILDRA 306 Query 307 SNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAV 366 NE LVTD ++ +L LEPVA+ L C EL + I R GA YQRQ VA+++ G+L AV Sbjct 307 GNEELVTDAISKLLVELEPVAQRLGCLTELDGIRTIMRRGAGYQRQRAVARRNGGELDAV 366 Query 367 VDALVAEL 374 V +LVAE+ Sbjct 367 VASLVAEM 374 Lambda K H 0.322 0.136 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 722036454250 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40