BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0439c Length=311 Score E Sequences producing significant alignments: (Bits) Value gi|15607580|ref|NP_214953.1| short chain dehydrogenase [Mycobact... 637 0.0 gi|15839827|ref|NP_334864.1| short chain dehydrogenase [Mycobact... 636 2e-180 gi|339293489|gb|AEJ45600.1| short chain dehydrogenase [Mycobacte... 635 2e-180 gi|183980781|ref|YP_001849072.1| dehydrogenase/reductase [Mycoba... 505 3e-141 gi|118617073|ref|YP_905405.1| short chain dehydrogenase [Mycobac... 503 2e-140 gi|240169816|ref|ZP_04748475.1| short chain dehydrogenase [Mycob... 487 9e-136 gi|342859061|ref|ZP_08715715.1| short chain dehydrogenase [Mycob... 481 6e-134 gi|254819763|ref|ZP_05224764.1| short chain dehydrogenase [Mycob... 476 2e-132 gi|41410031|ref|NP_962867.1| short chain dehydrogenase [Mycobact... 474 6e-132 gi|336460325|gb|EGO39225.1| dehydrogenase of unknown specificity... 474 7e-132 gi|118464304|ref|YP_883837.1| short chain dehydrogenase [Mycobac... 473 2e-131 gi|254777148|ref|ZP_05218664.1| short chain dehydrogenase [Mycob... 473 2e-131 gi|342859057|ref|ZP_08715711.1| short chain dehydrogenase [Mycob... 445 5e-123 gi|15839447|ref|NP_334484.1| short chain dehydrogenase [Mycobact... 435 5e-120 gi|15607210|ref|NP_214582.1| short chain dehydrogenase [Mycobact... 434 1e-119 gi|289445596|ref|ZP_06435340.1| oxidoreductase [Mycobacterium tu... 434 1e-119 gi|339630151|ref|YP_004721793.1| oxidoreductase [Mycobacterium a... 432 3e-119 gi|296167992|ref|ZP_06850105.1| short-chain dehydrogenase/reduct... 431 5e-119 gi|118469642|ref|YP_885266.1| short chain dehydrogenase [Mycobac... 427 1e-117 gi|118471698|ref|YP_885280.1| short chain dehydrogenase [Mycobac... 426 2e-117 gi|289441436|ref|ZP_06431180.1| oxidoreductase [Mycobacterium tu... 425 5e-117 gi|15827080|ref|NP_301343.1| short chain dehydrogenase [Mycobact... 422 4e-116 gi|333989068|ref|YP_004521682.1| dehydrogenase/reductase [Mycoba... 421 9e-116 gi|145220756|ref|YP_001131434.1| short chain dehydrogenase [Myco... 418 4e-115 gi|315442291|ref|YP_004075170.1| hypothetical protein Mspyr1_063... 416 2e-114 gi|182677034|ref|YP_001831180.1| short chain dehydrogenase [Beij... 415 4e-114 gi|298527465|ref|ZP_07014874.1| short chain dehydrogenase [Mycob... 414 8e-114 gi|108797576|ref|YP_637773.1| short chain dehydrogenase [Mycobac... 414 1e-113 gi|126433208|ref|YP_001068899.1| short chain dehydrogenase [Myco... 413 2e-113 gi|126433199|ref|YP_001068890.1| short chain dehydrogenase [Myco... 412 4e-113 gi|108797585|ref|YP_637782.1| short chain dehydrogenase [Mycobac... 409 3e-112 gi|152966739|ref|YP_001362523.1| short chain dehydrogenase [Kine... 405 3e-111 gi|326330990|ref|ZP_08197289.1| oxidoreductase, short-chain dehy... 405 6e-111 gi|344999238|ref|YP_004802092.1| short-chain dehydrogenase/reduc... 402 3e-110 gi|345014089|ref|YP_004816443.1| short-chain dehydrogenase/reduc... 401 7e-110 gi|169627749|ref|YP_001701398.1| short chain dehydrogenase [Myco... 399 3e-109 gi|315442299|ref|YP_004075178.1| hypothetical protein Mspyr1_063... 392 4e-107 gi|318062505|ref|ZP_07981226.1| short chain dehydrogenase [Strep... 391 6e-107 gi|302519700|ref|ZP_07272042.1| light-dependent protochlorophyll... 391 9e-107 gi|145220748|ref|YP_001131426.1| short chain dehydrogenase [Myco... 390 2e-106 gi|329940849|ref|ZP_08290129.1| putative oxidoreductase [Strepto... 389 2e-106 gi|333026481|ref|ZP_08454545.1| putative short chain dehydrogena... 389 2e-106 gi|120401777|ref|YP_951606.1| short chain dehydrogenase [Mycobac... 385 3e-105 gi|169627746|ref|YP_001701395.1| short chain dehydrogenase [Myco... 385 5e-105 gi|318081453|ref|ZP_07988779.1| short chain dehydrogenase [Strep... 384 1e-104 gi|120401768|ref|YP_951597.1| short chain dehydrogenase [Mycobac... 380 1e-103 gi|315506558|ref|YP_004085445.1| short-chain dehydrogenase/reduc... 379 4e-103 gi|256377425|ref|YP_003101085.1| short chain dehydrogenase [Acti... 379 5e-103 gi|302867004|ref|YP_003835641.1| short-chain dehydrogenase/reduc... 378 7e-103 gi|296138583|ref|YP_003645826.1| short-chain dehydrogenase/reduc... 377 9e-103 >gi|15607580|ref|NP_214953.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|31791617|ref|NP_854110.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97] gi|121636353|ref|YP_976576.1| short chain dehydrogenase [Mycobacterium bovis BCG str. Pasteur 1173P2] 73 more sequence titles Length=311 Score = 637 bits (1643), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/311 (100%), Positives = 311/311 (100%), Gaps = 0/311 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA Sbjct 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD Sbjct 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV Sbjct 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL 240 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL Sbjct 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL 240 Query 241 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV 300 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV Sbjct 241 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV 300 Query 301 SEELTGVSFGV 311 SEELTGVSFGV Sbjct 301 SEELTGVSFGV 311 >gi|15839827|ref|NP_334864.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|254230789|ref|ZP_04924116.1| hypothetical protein TBCG_00431 [Mycobacterium tuberculosis C] gi|13879959|gb|AAK44678.1| oxidoreductase, short-chain dehydrogenase/reductase family [Mycobacterium tuberculosis CDC1551] gi|124599848|gb|EAY58858.1| hypothetical protein TBCG_00431 [Mycobacterium tuberculosis C] Length=338 Score = 636 bits (1640), Expect = 2e-180, Method: Compositional matrix adjust. Identities = 311/311 (100%), Positives = 311/311 (100%), Gaps = 0/311 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA Sbjct 28 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 87 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD Sbjct 88 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 147 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV Sbjct 148 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 207 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL 240 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL Sbjct 208 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL 267 Query 241 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV 300 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV Sbjct 268 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV 327 Query 301 SEELTGVSFGV 311 SEELTGVSFGV Sbjct 328 SEELTGVSFGV 338 >gi|339293489|gb|AEJ45600.1| short chain dehydrogenase [Mycobacterium tuberculosis CCDC5079] Length=311 Score = 635 bits (1638), Expect = 2e-180, Method: Compositional matrix adjust. Identities = 310/311 (99%), Positives = 310/311 (99%), Gaps = 0/311 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 MTANDNKTRKWSA DVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA Sbjct 1 MTANDNKTRKWSAVDVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD Sbjct 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV Sbjct 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL 240 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL Sbjct 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL 240 Query 241 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV 300 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV Sbjct 241 LFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTV 300 Query 301 SEELTGVSFGV 311 SEELTGVSFGV Sbjct 301 SEELTGVSFGV 311 >gi|183980781|ref|YP_001849072.1| dehydrogenase/reductase [Mycobacterium marinum M] gi|183174107|gb|ACC39217.1| dehydrogenase/reductase [Mycobacterium marinum M] Length=312 Score = 505 bits (1301), Expect = 3e-141, Method: Compositional matrix adjust. Identities = 254/312 (82%), Positives = 280/312 (90%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M+AN WSA+D+PDQSGRVVVVTGANTG+GYHTA A RGAHVVLAVRN EKGNA Sbjct 1 MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVLAVRNPEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A A+I+AA+P A VTLQ LDL SLDSVR+AADALR+AYPRID+LINNAGVMWTPKQVTKD Sbjct 61 AVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPRIDLLINNAGVMWTPKQVTKD 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFE+QFGTNHLGHFALTGL+LDH+LPVPGSRV+TVSS GHRI AAIHFDDLQWER YNRV Sbjct 121 GFEMQFGTNHLGHFALTGLLLDHLLPVPGSRVITVSSLGHRIRAAIHFDDLQWERSYNRV 180 Query 181 AAYGQAKLANLLFTYELQRRL-GEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL ++ +TIAVAAHPGGSNTEL RNLPR++ P+A +LGP Sbjct 181 AAYGQSKLANLLFTYELQRRLAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGP 240 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 LFQS +MGALPTLRAATDP+ GGQYYGPDGF EQRGHPK+VQSSAQSHD+DLQRRLWT Sbjct 241 ALFQSAQMGALPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT 300 Query 300 VSEELTGVSFGV 311 VSEELTGVSF V Sbjct 301 VSEELTGVSFPV 312 >gi|118617073|ref|YP_905405.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99] gi|118569183|gb|ABL03934.1| dehydrogenase/reductase [Mycobacterium ulcerans Agy99] Length=312 Score = 503 bits (1294), Expect = 2e-140, Method: Compositional matrix adjust. Identities = 252/312 (81%), Positives = 278/312 (90%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M+A WSA+D+PDQSGRVVVVTGANTG+GYHTA ADRGAHVVLAVRN EKGNA Sbjct 1 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVLAVRNPEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A A+I+AA+P A VTLQ LDL SLDSVR+AADALR+AYPRID+LINNAGVMWTPKQVTKD Sbjct 61 AVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPRIDLLINNAGVMWTPKQVTKD 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFE+QFGTNHLGHFALTGL+LDH+LPVPGSRV+TVSS GHRI AAIHFDDLQWER YNRV Sbjct 121 GFEMQFGTNHLGHFALTGLLLDHLLPVPGSRVITVSSLGHRIRAAIHFDDLQWERSYNRV 180 Query 181 AAYGQAKLANLLFTYELQRRL-GEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL ++ +TIAVAAHPG SNTEL RNLPR++ P+A +LGP Sbjct 181 AAYGQSKLANLLFTYELQRRLAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGP 240 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 LFQS +MGALPTLR ATDP+ GGQYYGPDGF EQRGHPK+VQSSAQSHD+DLQRRLWT Sbjct 241 ALFQSAQMGALPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRLWT 300 Query 300 VSEELTGVSFGV 311 VSEELTGVSF V Sbjct 301 VSEELTGVSFPV 312 >gi|240169816|ref|ZP_04748475.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=316 Score = 487 bits (1254), Expect = 9e-136, Method: Compositional matrix adjust. Identities = 244/312 (79%), Positives = 277/312 (89%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 ++ N + RKWS AD+PDQSGRVVVVTGANTG+GYHTAAV A RGAHVVLAVR+ EKGN+ Sbjct 5 VSKNATENRKWSRADIPDQSGRVVVVTGANTGLGYHTAAVLAFRGAHVVLAVRSPEKGNS 64 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A ARI+AA+P A +TLQ+LDL SLDSVRAAA+ALR+ YPRID+LINNAGVMWTPKQ TKD Sbjct 65 ALARIVAAKPQADITLQELDLSSLDSVRAAAEALRSTYPRIDLLINNAGVMWTPKQTTKD 124 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFE+QFGTNHLGHFALTGL+LD +LPV GSRVVTVSS GHRI AAIHFDDLQWER Y+R+ Sbjct 125 GFEMQFGTNHLGHFALTGLLLDRLLPVRGSRVVTVSSLGHRIRAAIHFDDLQWERGYDRI 184 Query 181 AAYGQAKLANLLFTYELQRRL-GEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL + +TIAVAAHPGGSNTEL R+LPR++RP++ +LGP Sbjct 185 AAYGQSKLANLLFTYELQRRLAADPDAATIAVAAHPGGSNTELARHLPRIVRPLSNILGP 244 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 +LFQS EMGALPTLRAATDP+ GGQYYGPDGF EQRGHPK+VQSS SHD++LQRRLW Sbjct 245 VLFQSAEMGALPTLRAATDPSVAGGQYYGPDGFLEQRGHPKLVQSSPASHDEELQRRLWA 304 Query 300 VSEELTGVSFGV 311 VSEELTGV F V Sbjct 305 VSEELTGVRFPV 316 >gi|342859061|ref|ZP_08715715.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342133302|gb|EGT86505.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] Length=312 Score = 481 bits (1238), Expect = 6e-134, Method: Compositional matrix adjust. Identities = 248/312 (80%), Positives = 269/312 (87%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M +ND + R WS DVPDQSGRVVVVTGANTGIGY TAAV A RGAHVVLAVRNLEKGNA Sbjct 1 MASNDTENRNWSEGDVPDQSGRVVVVTGANTGIGYETAAVLAYRGAHVVLAVRNLEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A ARI+AA P A VTLQQLDL SLD++R+AADALR AYPRID+LINNAGVMWTPKQVT D Sbjct 61 ALARIVAASPRADVTLQQLDLTSLDAIRSAADALRAAYPRIDLLINNAGVMWTPKQVTAD 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGL+LD++L V SRVVTVSS GHR+ AAIHFDDLQWE Y+R+ Sbjct 121 GFELQFGTNHLGHFALTGLLLDNLLSVRDSRVVTVSSLGHRLRAAIHFDDLQWEHGYDRI 180 Query 181 AAYGQAKLANLLFTYELQRRL-GEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL A TIAVAAHPGGSNTEL RNLP + RP+ VLGP Sbjct 181 AAYGQSKLANLLFTYELQRRLAANADARTIAVAAHPGGSNTELARNLPGVFRPLKAVLGP 240 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 +LFQSP MGALPTLRAATDP QGGQYYGP GF EQRG PK+V+SSAQSHD++ QRRLW Sbjct 241 VLFQSPAMGALPTLRAATDPAVQGGQYYGPAGFLEQRGRPKLVESSAQSHDEESQRRLWA 300 Query 300 VSEELTGVSFGV 311 VSEELTGVSF V Sbjct 301 VSEELTGVSFPV 312 >gi|254819763|ref|ZP_05224764.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=316 Score = 476 bits (1226), Expect = 2e-132, Method: Compositional matrix adjust. Identities = 246/316 (78%), Positives = 270/316 (86%), Gaps = 5/316 (1%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M +ND +TR WS +DVPDQSGRVVV+TGANTGIGY AAV A RGAHVVLAVRNLEKGNA Sbjct 1 MASNDKETRAWSESDVPDQSGRVVVITGANTGIGYEAAAVLAHRGAHVVLAVRNLEKGNA 60 Query 61 ARARIMAA----RPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQ 116 A +RI+AA VTLQQLDL SLD+VR+AADALR AYPRID+LINNAGVMWTPKQ Sbjct 61 ALSRIVAAGGQGSREVDVTLQQLDLTSLDAVRSAADALRAAYPRIDLLINNAGVMWTPKQ 120 Query 117 VTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERR 176 VT DGFELQFGTNHLGHFALTGL+LDH+LPV SRVVT+SS GHR+ AAIHFDDLQWE R Sbjct 121 VTADGFELQFGTNHLGHFALTGLLLDHLLPVRDSRVVTISSLGHRLRAAIHFDDLQWEHR 180 Query 177 YNRVAAYGQAKLANLLFTYELQRRLGEAGKS-TIAVAAHPGGSNTELTRNLPRLIRPVAT 235 Y+R+AAYGQ+KLANLLFTYELQRRL + TIAVAAHPGGSNTELTRNLP + RP A Sbjct 181 YDRIAAYGQSKLANLLFTYELQRRLAATPDAKTIAVAAHPGGSNTELTRNLPAIFRPAAA 240 Query 236 VLGPLLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQR 295 LGP+LFQS MGALPTLRAATDP +GGQY+GPDGF EQRGHPK+V+SSAQSHD +LQR Sbjct 241 ALGPVLFQSAAMGALPTLRAATDPDVEGGQYFGPDGFLEQRGHPKLVKSSAQSHDAELQR 300 Query 296 RLWTVSEELTGVSFGV 311 RLW VSEELTGV F V Sbjct 301 RLWAVSEELTGVRFPV 316 >gi|41410031|ref|NP_962867.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398864|gb|AAS06483.1| hypothetical protein MAP_3933c [Mycobacterium avium subsp. paratuberculosis K-10] Length=312 Score = 474 bits (1221), Expect = 6e-132, Method: Compositional matrix adjust. Identities = 248/312 (80%), Positives = 270/312 (87%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M +D + R WS ADV DQSGRVVV+TGANTGIGY TAAV A RGAHVVLAVR+LEKGNA Sbjct 1 MAPHDKQHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVLAVRDLEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A +RI+AA P A VTLQQLDL SL SVR+AA+ALR AYPRID+LINNAGVMWTPKQVT+D Sbjct 61 ALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPRIDLLINNAGVMWTPKQVTED 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGL+LDH+L V SRVVTVSS GHR+ AAIHFDDL WERRY+RV Sbjct 121 GFELQFGTNHLGHFALTGLLLDHLLGVRDSRVVTVSSLGHRLRAAIHFDDLHWERRYDRV 180 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKS-TIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL A + TIAVAAHPGGSNTEL R+LP + RPV VLGP Sbjct 181 AAYGQSKLANLLFTYELQRRLAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGP 240 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 +LFQSP MGALPTLRAATDP QGGQYYGPDGF EQRG PK+V+SSAQSHD+ LQRRLW Sbjct 241 VLFQSPAMGALPTLRAATDPAVQGGQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA 300 Query 300 VSEELTGVSFGV 311 VSEELTGV F V Sbjct 301 VSEELTGVHFPV 312 >gi|336460325|gb|EGO39225.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [Mycobacterium avium subsp. paratuberculosis S397] Length=316 Score = 474 bits (1220), Expect = 7e-132, Method: Compositional matrix adjust. Identities = 248/312 (80%), Positives = 270/312 (87%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M +D + R WS ADV DQSGRVVV+TGANTGIGY TAAV A RGAHVVLAVR+LEKGNA Sbjct 5 MAPHDKQHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVLAVRDLEKGNA 64 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A +RI+AA P A VTLQQLDL SL SVR+AA+ALR AYPRID+LINNAGVMWTPKQVT+D Sbjct 65 ALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPRIDLLINNAGVMWTPKQVTED 124 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGL+LDH+L V SRVVTVSS GHR+ AAIHFDDL WERRY+RV Sbjct 125 GFELQFGTNHLGHFALTGLLLDHLLGVRDSRVVTVSSLGHRLRAAIHFDDLHWERRYDRV 184 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKS-TIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL A + TIAVAAHPGGSNTEL R+LP + RPV VLGP Sbjct 185 AAYGQSKLANLLFTYELQRRLAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGP 244 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 +LFQSP MGALPTLRAATDP QGGQYYGPDGF EQRG PK+V+SSAQSHD+ LQRRLW Sbjct 245 VLFQSPAMGALPTLRAATDPAVQGGQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA 304 Query 300 VSEELTGVSFGV 311 VSEELTGV F V Sbjct 305 VSEELTGVHFPV 316 >gi|118464304|ref|YP_883837.1| short chain dehydrogenase [Mycobacterium avium 104] gi|118165591|gb|ABK66488.1| retinol dehydrogenase 13 [Mycobacterium avium 104] Length=312 Score = 473 bits (1217), Expect = 2e-131, Method: Compositional matrix adjust. Identities = 247/312 (80%), Positives = 269/312 (87%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M +D + R WS ADV DQSGRVVV+TGANTGIGY TAAV A RGAHVVLAVR+LEKGNA Sbjct 1 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVLAVRDLEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A +RI+AA P A VTLQQLDL SL SVR+AA+ALR AYPRID+LINNAGVMWTPKQVT+D Sbjct 61 ALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPRIDLLINNAGVMWTPKQVTED 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGL+LDH+L V SRVVTVSS GHR+ AAIHFDDL WERRY+RV Sbjct 121 GFELQFGTNHLGHFALTGLLLDHLLGVRDSRVVTVSSLGHRLRAAIHFDDLHWERRYDRV 180 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKS-TIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL A + TIAVAAHPGGSNTEL R+LP + RPV VLGP Sbjct 181 AAYGQSKLANLLFTYELQRRLAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGP 240 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 +LFQSP MGALPTLRAATDP QG QYYGPDGF EQRG PK+V+SSAQSHD+ LQRRLW Sbjct 241 VLFQSPAMGALPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA 300 Query 300 VSEELTGVSFGV 311 VSEELTGV F V Sbjct 301 VSEELTGVHFPV 312 >gi|254777148|ref|ZP_05218664.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] Length=312 Score = 473 bits (1217), Expect = 2e-131, Method: Compositional matrix adjust. Identities = 247/312 (80%), Positives = 269/312 (87%), Gaps = 1/312 (0%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M +D + R WS ADV DQSGRVVV+TGANTGIGY TAAV A RGAHVVLAVR+LEKGNA Sbjct 1 MAPHDKQHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVLAVRDLEKGNA 60 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A +RI+AA P A VTLQQLDL SL SVR+AA+ALR AYPRID+LINNAGVMWTPKQVT+D Sbjct 61 ALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPRIDLLINNAGVMWTPKQVTED 120 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQFGTNHLGHFALTGL+LDH+L V SRVVTVSS GHR+ AAIHFDDL WERRY+RV Sbjct 121 GFELQFGTNHLGHFALTGLLLDHLLGVRDSRVVTVSSLGHRLRAAIHFDDLHWERRYDRV 180 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKS-TIAVAAHPGGSNTELTRNLPRLIRPVATVLGP 239 AAYGQ+KLANLLFTYELQRRL A + TIAVAAHPGGSNTEL R+LP + RPV VLGP Sbjct 181 AAYGQSKLANLLFTYELQRRLAAAPDAKTIAVAAHPGGSNTELARHLPGIFRPVQAVLGP 240 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 +LFQSP MGALPTLRAATDP QG QYYGPDGF EQRG PK+V+SSAQSHD+ LQRRLW Sbjct 241 VLFQSPAMGALPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQRRLWA 300 Query 300 VSEELTGVSFGV 311 VSEELTGV F V Sbjct 301 VSEELTGVHFPV 312 >gi|342859057|ref|ZP_08715711.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342133298|gb|EGT86501.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] Length=304 Score = 445 bits (1144), Expect = 5e-123, Method: Compositional matrix adjust. Identities = 223/300 (75%), Positives = 244/300 (82%), Gaps = 1/300 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ AD+PDQ+GRV V+TGANTG+GY TA AD GA VVLAVRNL+KG A ARI A Sbjct 3 KWTTADIPDQTGRVAVITGANTGLGYETALALADHGARVVLAVRNLDKGKDAAARITAQS 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 P A V LQ+LDL SLDSVRAAA+ LR+A+ RID+LINNAGVMWTPK TKDGFELQFGTN Sbjct 63 PDADVALQELDLTSLDSVRAAAEQLRSAHDRIDLLINNAGVMWTPKSTTKDGFELQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFA TGL+LD +LPV GSRVVTVSS GHRI A IHFDDLQWERRYNR+AAYGQAKLA Sbjct 123 HLGHFAFTGLLLDRLLPVAGSRVVTVSSLGHRILADIHFDDLQWERRYNRIAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTYELQRRL G +TIAVAAHPGGS TELTRNLP L V T + L+ Q MGA Sbjct 183 NLMFTYELQRRLAPQG-TTIAVAAHPGGSRTELTRNLPPLAERVVTPVFGLISQDAAMGA 241 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GGQYYGPDG GE +GHPKVV SS +SHD QRRLWTVSEELTGV + Sbjct 242 LPTLRAATDPGVLGGQYYGPDGLGEMQGHPKVVASSERSHDVAAQRRLWTVSEELTGVVY 301 >gi|15839447|ref|NP_334484.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|31791245|ref|NP_853738.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97] gi|121635979|ref|YP_976202.1| short chain dehydrogenase [Mycobacterium bovis BCG str. Pasteur 1173P2] 59 more sequence titles Length=303 Score = 435 bits (1118), Expect = 5e-120, Method: Compositional matrix adjust. Identities = 221/302 (74%), Positives = 252/302 (84%), Gaps = 2/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+AAD+PDQ+GR V+TGANTG+G+ TAA A GAHVVLAVRNL+KG A ARI A Sbjct 3 KWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEAT 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SL SVRAAA L++ + RID+LINNAGVM+TP+Q T DGFE+QFGTN Sbjct 63 PGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPV GSRVVT+SS GHRI AAIHFDDLQWERRY RVAAYGQAKLA Sbjct 123 HLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIAVA+HPG SNTEL RN+PR + VA +L PL+ Q E+GA Sbjct 183 NLLFTYELQRRLAPGG-TTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLM-QDAELGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP +GGQY+GPDGFGE RG+PKVV SSAQSHD+ LQRRLW VSEELTGV + Sbjct 241 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY 300 Query 310 GV 311 V Sbjct 301 PV 302 >gi|15607210|ref|NP_214582.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|148659828|ref|YP_001281351.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Ra] gi|167970596|ref|ZP_02552873.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Ra] 10 more sequence titles Length=303 Score = 434 bits (1115), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 220/302 (73%), Positives = 252/302 (84%), Gaps = 2/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+AAD+PDQ+GR V+TGANTG+G+ TAA A GAHVVLAVRNL+KG A ARI A Sbjct 3 KWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEAT 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SL SVRAAA L++ + RID+LINNAGVM+TP+Q T DGFE+QFGTN Sbjct 63 PGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPV GSRVVT+SS GHRI AAIHFDDLQWERRY RVAAYGQAKLA Sbjct 123 HLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIAVA+HPG SNTE+ RN+PR + VA +L PL+ Q E+GA Sbjct 183 NLLFTYELQRRLAPGG-TTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLM-QDAELGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP +GGQY+GPDGFGE RG+PKVV SSAQSHD+ LQRRLW VSEELTGV + Sbjct 241 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY 300 Query 310 GV 311 V Sbjct 301 PV 302 >gi|289445596|ref|ZP_06435340.1| oxidoreductase [Mycobacterium tuberculosis CPHL_A] gi|289418554|gb|EFD15755.1| oxidoreductase [Mycobacterium tuberculosis CPHL_A] Length=303 Score = 434 bits (1115), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 221/302 (74%), Positives = 251/302 (84%), Gaps = 2/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW AAD+PDQ+GR V+TGANTG+G+ TAA A GAHVVLAVRNL+KG A ARI A Sbjct 3 KWPAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEAT 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SL SVRAAA L++ + RID+LINNAGVM+TP+Q T DGFE+QFGTN Sbjct 63 PGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPV GSRVVT+SS GHRI AAIHFDDLQWERRY RVAAYGQAKLA Sbjct 123 HLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIAVA+HPG SNTEL RN+PR + VA +L PL+ Q E+GA Sbjct 183 NLLFTYELQRRLAPGG-TTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLM-QDAELGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP +GGQY+GPDGFGE RG+PKVV SSAQSHD+ LQRRLW VSEELTGV + Sbjct 241 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY 300 Query 310 GV 311 V Sbjct 301 PV 302 >gi|339630151|ref|YP_004721793.1| oxidoreductase [Mycobacterium africanum GM041182] gi|339329507|emb|CCC25142.1| putative oxidoreductase [Mycobacterium africanum GM041182] Length=303 Score = 432 bits (1112), Expect = 3e-119, Method: Compositional matrix adjust. Identities = 220/302 (73%), Positives = 252/302 (84%), Gaps = 2/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+AAD+PDQ+GR V+TGANTG+G+ TAA A GAHVVLAVRNL+KG A ARI A Sbjct 3 KWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEAT 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SL SVRAAA L++ + RID+LINNAGVM+TP+Q T DGFE+QFGTN Sbjct 63 PGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPV GSRVVT+SS GHRI AAIHFDDLQWERR RVAAYGQAKLA Sbjct 123 HLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRCRRVAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIAVA+HPG SNTEL RN+PR + VA +L PL+ Q E+GA Sbjct 183 NLLFTYELQRRLAPGG-TTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLM-QDAELGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP +GGQY+GPDGFGE RG+PKVV SSAQSHD++LQRRLW VSEELTGV + Sbjct 241 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEELQRRLWAVSEELTGVVY 300 Query 310 GV 311 V Sbjct 301 PV 302 >gi|296167992|ref|ZP_06850105.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896918|gb|EFG76545.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=304 Score = 431 bits (1109), Expect = 5e-119, Method: Compositional matrix adjust. Identities = 221/302 (74%), Positives = 245/302 (82%), Gaps = 1/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ AD+PDQ+GRV V+TGANTG+GY TAA AD GA VVLAVRNL+KG A ARI A Sbjct 3 NWTVADIPDQTGRVAVITGANTGLGYETAAALADHGARVVLAVRNLDKGKDAAARIAAKS 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SLDSVR AA+ L++ Y ID+LINNAGVM+TPK+ TKDGFELQFGTN Sbjct 63 PGADVALQELDLTSLDSVRTAAERLKSDYDHIDLLINNAGVMYTPKETTKDGFELQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+L+ +LPVPGSRVVTVSS GHRI A IHFDDLQWER YNRVAAYGQAKLA Sbjct 123 HLGHFALTGLLLERLLPVPGSRVVTVSSMGHRILADIHFDDLQWERSYNRVAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIA AAHPGGSNTEL R P + RP+ V ++ Q MGA Sbjct 183 NLLFTYELQRRLAPHG-TTIAAAAHPGGSNTELGRYTPTVFRPLVNVFFSVIAQDAAMGA 241 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GGQYYGPDGF E RGHPK+V SSA+SHD D QRRLWTVSEELTGV + Sbjct 242 LPTLRAATDPAVLGGQYYGPDGFAETRGHPKIVSSSAKSHDPDRQRRLWTVSEELTGVRY 301 Query 310 GV 311 V Sbjct 302 PV 303 >gi|118469642|ref|YP_885266.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118170929|gb|ABK71825.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=307 Score = 427 bits (1098), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 211/302 (70%), Positives = 242/302 (81%), Gaps = 0/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ ADVPDQSGRV +VTG+NTG+GY TA A +GAHVV+AVRNL+KG A RIMA+ Sbjct 6 KWTEADVPDQSGRVAIVTGSNTGLGYETARALAAKGAHVVIAVRNLDKGRDAVDRIMAST 65 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 P A + LQ+LD+ SLDSVR AAD L+ AYP ID+LINNAGVM+ PKQ T DGFELQFGTN Sbjct 66 PKADLKLQKLDVGSLDSVRTAADELKGAYPHIDLLINNAGVMYPPKQTTVDGFELQFGTN 125 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLG FALTGL++DH+LPV GSRVV V+S HRI A IHF+DLQWERRYNRV AYGQ+KLA Sbjct 126 HLGPFALTGLLIDHLLPVEGSRVVAVASVAHRIRAKIHFEDLQWERRYNRVEAYGQSKLA 185 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLF YELQRRL AGK TI+VAAHPG SNTEL R++P P + L SP MGA Sbjct 186 NLLFAYELQRRLAAAGKPTISVAAHPGLSNTELMRHIPGTGLPGYHQIASLFSNSPLMGA 245 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 L TLRAATDP +GGQYYGPDGF E RGHP++V+SS+QS D +LQRRLW VSEELTGVS+ Sbjct 246 LATLRAATDPGVKGGQYYGPDGFREVRGHPELVKSSSQSRDPELQRRLWAVSEELTGVSY 305 Query 310 GV 311 V Sbjct 306 PV 307 >gi|118471698|ref|YP_885280.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118172985|gb|ABK73881.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=305 Score = 426 bits (1096), Expect = 2e-117, Method: Compositional matrix adjust. Identities = 218/306 (72%), Positives = 242/306 (80%), Gaps = 14/306 (4%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ A +PDQ+GRV +VTGANTG+G TA A +GAHVVLAVRNL+KG AA I + Sbjct 3 KWTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVLAVRNLDKGKAAVDWIARSA 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 P A + LQQLDL SL SVRAAAD L+ + RID+L+NNAGVMW P+Q T DGFELQFGTN Sbjct 63 PTADLELQQLDLGSLASVRAAADDLKGKFDRIDLLVNNAGVMWPPRQTTADGFELQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD ML VPGSRVVTVSSQGHRI AAIHFDDLQWERRYNRVAAYGQ+KLA Sbjct 123 HLGHFALTGLLLDRMLTVPGSRVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLP----RLIRPVATVLGPLLFQSP 245 NLLFTYELQRRL G T A+AAHPG SNTEL R+LP RL+ P+A Q Sbjct 183 NLLFTYELQRRL--TGHQTTALAAHPGASNTELARHLPGALERLVTPLA--------QDA 232 Query 246 EMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELT 305 +GALPTLRAATDP GGQY+GPDG GE RG+PKVV SSAQSHD DLQRRLW VSEELT Sbjct 233 ALGALPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQRRLWAVSEELT 292 Query 306 GVSFGV 311 GV+F V Sbjct 293 GVTFPV 298 >gi|289441436|ref|ZP_06431180.1| oxidoreductase [Mycobacterium tuberculosis T46] gi|289414355|gb|EFD11595.1| oxidoreductase [Mycobacterium tuberculosis T46] Length=303 Score = 425 bits (1092), Expect = 5e-117, Method: Compositional matrix adjust. Identities = 217/302 (72%), Positives = 248/302 (83%), Gaps = 2/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+AAD+PDQ+GR V+TGANTG+G+ TAA A GAHVVLAVRNL+KG A ARI A Sbjct 3 KWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEAT 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SL SVRAAA L++ + RID+LINNAGVM+TP+Q T DGFE+QFGTN Sbjct 63 PGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPV GSRVVT+SS GHRI AAIHFDDLQWERRY RVAAYGQ Sbjct 123 HLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQIGEL 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIAVA+HPG SNTEL RN+PR + VA +L PL+ Q E+GA Sbjct 183 NLLFTYELQRRLAPGG-TTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLM-QDAELGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP +GGQY+GPDGFGE RG+PKVV SSAQSHD+ LQRRLW VSEELTGV + Sbjct 241 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY 300 Query 310 GV 311 V Sbjct 301 PV 302 >gi|15827080|ref|NP_301343.1| short chain dehydrogenase [Mycobacterium leprae TN] gi|221229558|ref|YP_002502974.1| short chain dehydrogenase [Mycobacterium leprae Br4923] gi|4154042|emb|CAA22691.1| putative oxidoreductase [Mycobacterium leprae] gi|13092628|emb|CAC29823.1| putative oxidoreductase [Mycobacterium leprae] gi|219932665|emb|CAR70408.1| putative oxidoreductase [Mycobacterium leprae Br4923] Length=304 Score = 422 bits (1085), Expect = 4e-116, Method: Compositional matrix adjust. Identities = 209/302 (70%), Positives = 236/302 (79%), Gaps = 1/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ AD+PDQ+GRV V+TGANTG+GY TA A+ GAHVVLAVRNL+KG A ARI A Sbjct 3 KWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVLAVRNLDKGKDAAARITATS 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 +V LQ+LDL SL+SVRAAA LR+ Y ID+LINNAGVMWTPK TKDGFELQFGTN Sbjct 63 AQNNVALQELDLASLESVRAAAKQLRSDYDHIDLLINNAGVMWTPKSTTKDGFELQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFA TGL+LD +LP+ GSRV+TVSS HR+ A IHF+DLQWE YNRVAAYGQ+KLA Sbjct 123 HLGHFAFTGLLLDRLLPIVGSRVITVSSLSHRLFADIHFNDLQWECNYNRVAAYGQSKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL ++TIAVAAHPGGS TELTR LP LI P+ +V L Q GA Sbjct 183 NLLFTYELQRRLATR-QTTIAVAAHPGGSRTELTRTLPALIAPIFSVAELFLTQDAATGA 241 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATD GGQY+GPDGF E RGHPKVV S+ +SHD D Q RLW VSEELTGV + Sbjct 242 LPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRLWAVSEELTGVVY 301 Query 310 GV 311 V Sbjct 302 PV 303 >gi|333989068|ref|YP_004521682.1| dehydrogenase/reductase [Mycobacterium sp. JDM601] gi|333485036|gb|AEF34428.1| dehydrogenase/reductase [Mycobacterium sp. JDM601] Length=302 Score = 421 bits (1082), Expect = 9e-116, Method: Compositional matrix adjust. Identities = 212/302 (71%), Positives = 241/302 (80%), Gaps = 2/302 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ AD+PDQ+GRV VVTGANTG+G+ TAA A RGAHVVLAVRNL+KG A I Sbjct 3 KWTTADIPDQAGRVAVVTGANTGLGFETAAGLAARGAHVVLAVRNLDKGRDAETLIRQRS 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SLDS+ AAA+ LR+ + RID+LINNAGVM+ PK TKDGFELQFGTN Sbjct 63 PGASVALQELDLGSLDSICAAAEQLRSGHDRIDLLINNAGVMYPPKSTTKDGFELQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFA TGL+LD +LPV GSRVVTVSS GHR+ A IHFDDLQWERRYNRV AYGQ+KLA Sbjct 123 HLGHFAFTGLLLDRLLPVAGSRVVTVSSLGHRLRADIHFDDLQWERRYNRVEAYGQSKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL +TIA+AAHPGGSNTEL R+LPR ++ P +FQ +MGA Sbjct 183 NLLFTYELQRRLAPRA-TTIALAAHPGGSNTELMRHLPRWAAVAYPLIKP-MFQGADMGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GGQY+GPDG + RGHPKVV SS +SHD +LQRRLW VSEELTGV + Sbjct 241 LPTLRAATDPQALGGQYFGPDGLTQGRGHPKVVASSRKSHDVELQRRLWAVSEELTGVVY 300 Query 310 GV 311 V Sbjct 301 PV 302 >gi|145220756|ref|YP_001131434.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|145213242|gb|ABP42646.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum PYR-GCK] Length=305 Score = 418 bits (1075), Expect = 4e-115, Method: Compositional matrix adjust. Identities = 209/304 (69%), Positives = 240/304 (79%), Gaps = 0/304 (0%) Query 8 TRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMA 67 T KW+AADVPDQSGRV VVTGANTGIGY TA V A +GA VV+AVR+ KG A I Sbjct 2 TSKWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVIAVRDAGKGQKALDAITR 61 Query 68 ARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFG 127 PGA V+LQ+LDL SL SVR A DALR+A+PRID+LINNAGVM+ PKQVT+DGFELQFG Sbjct 62 KHPGAAVSLQELDLSSLGSVRRATDALRSAHPRIDLLINNAGVMYPPKQVTRDGFELQFG 121 Query 128 TNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAK 187 TNHLGHFA TGL+LD++L VPGSRVVTV+S H+ A IHFDDLQWER+YNRVAAYGQ+K Sbjct 122 TNHLGHFAFTGLLLDNLLDVPGSRVVTVASLAHKNLADIHFDDLQWERKYNRVAAYGQSK 181 Query 188 LANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEM 247 LANL+FTYELQRRL G TIAVAAHPG SNTEL R++P P L L+ +P + Sbjct 182 LANLMFTYELQRRLAARGAPTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTPAV 241 Query 248 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGV 307 GALPT+RAATDP GGQYYGP GF E GHP +V S+ +SHD +Q+RLWTVSEELTGV Sbjct 242 GALPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQQRLWTVSEELTGV 301 Query 308 SFGV 311 +GV Sbjct 302 KYGV 305 >gi|315442291|ref|YP_004075170.1| hypothetical protein Mspyr1_06300 [Mycobacterium sp. Spyr1] gi|315260594|gb|ADT97335.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [Mycobacterium sp. Spyr1] Length=305 Score = 416 bits (1069), Expect = 2e-114, Method: Compositional matrix adjust. Identities = 208/304 (69%), Positives = 240/304 (79%), Gaps = 0/304 (0%) Query 8 TRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMA 67 T KW+AADVPDQSGRVVVVTGANTGIGY TA V A +GA VV+AVR+ KG A I Sbjct 2 TSKWTAADVPDQSGRVVVVTGANTGIGYETAEVLAGKGARVVIAVRDAGKGQKALDAITR 61 Query 68 ARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFG 127 PGA V+LQ+LDL SL SVR A DALR+A+PRID+LINNAGVM+ PKQ T+DGFELQFG Sbjct 62 KHPGAAVSLQELDLSSLGSVRRATDALRSAHPRIDLLINNAGVMYPPKQFTRDGFELQFG 121 Query 128 TNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAK 187 TNHLGHFA TGL+LD++L VPGSRVVTV+S H+ A IHFDDLQWER+YNRVAAYGQ+K Sbjct 122 TNHLGHFAFTGLLLDNLLDVPGSRVVTVASLAHKNLADIHFDDLQWERKYNRVAAYGQSK 181 Query 188 LANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEM 247 LANL+FTYELQRRL G TIAVAAHPG SNTEL R++P P L L+ +P + Sbjct 182 LANLMFTYELQRRLAARGAPTIAVAAHPGISNTELMRHVPGTSLPGVMKLAGLVTNTPAV 241 Query 248 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGV 307 GALPT+RAATDP GGQYYGP GF E GHP +V S+ +SHD +Q+RLWTVSE+LTGV Sbjct 242 GALPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNRKSHDVAVQQRLWTVSEDLTGV 301 Query 308 SFGV 311 +GV Sbjct 302 KYGV 305 >gi|182677034|ref|YP_001831180.1| short chain dehydrogenase [Beijerinckia indica subsp. indica ATCC 9039] gi|182632917|gb|ACB93691.1| short-chain dehydrogenase/reductase SDR [Beijerinckia indica subsp. indica ATCC 9039] Length=300 Score = 415 bits (1067), Expect = 4e-114, Method: Compositional matrix adjust. Identities = 208/302 (69%), Positives = 238/302 (79%), Gaps = 6/302 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ ++ DQ GR+ +VTG NTG+G+ TA + A GA VVLAVR++EKG A ARI Sbjct 4 NWTEQNISDQHGRIAIVTGGNTGLGFETARMLAAHGAKVVLAVRDVEKGGQAAARI---- 59 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 V +Q LDL SLDS+R+AA LR AYPRID+LINNAGVM+TP+Q T DGFELQFGTN Sbjct 60 -AGDVAVQALDLTSLDSIRSAAADLRAAYPRIDLLINNAGVMYTPRQTTSDGFELQFGTN 118 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+R AYGQ+KLA Sbjct 119 HLGHFALTGLLIDRLLPVPGSRVVTVSSTGHRIQAAIHFDDLQWERSYSRAGAYGQSKLA 178 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTYELQRRL G +TIAVAAHPG SNTEL RNLP R L PLL Q PEMGA Sbjct 179 NLMFTYELQRRLAPHG-ATIAVAAHPGVSNTELIRNLPAAFRGPIRWLAPLLTQKPEMGA 237 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GGQYYGP G+GE RG+PK+V SSA S+D+ +QRRLWTVSEELTGV+F Sbjct 238 LPTLRAATDPAVLGGQYYGPGGWGEVRGYPKLVTSSADSYDQAVQRRLWTVSEELTGVTF 297 Query 310 GV 311 V Sbjct 298 PV 299 >gi|298527465|ref|ZP_07014874.1| short chain dehydrogenase [Mycobacterium tuberculosis 94_M4241A] gi|298497259|gb|EFI32553.1| short chain dehydrogenase [Mycobacterium tuberculosis 94_M4241A] Length=306 Score = 414 bits (1065), Expect = 8e-114, Method: Compositional matrix adjust. Identities = 212/293 (73%), Positives = 243/293 (83%), Gaps = 4/293 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+AAD+PDQ+GR V+TGANTG+G+ TAA A GAHVVLAVRNL+KG A ARI A Sbjct 3 KWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEAT 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PGA V LQ+LDL SL SVRAAA L++ + RID+LINNAGVM+TP+Q T DGFE+QFGTN Sbjct 63 PGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL++D +LPV GSRVVT+SS GHRI AAIHFDDLQWERRY RVAAYGQAKLA Sbjct 123 HLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL G +TIAVA+HPG SNTEL RN+PR + VA +L PL+ Q E+GA Sbjct 183 NLLFTYELQRRLAPGG-TTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLM-QDAELGA 240 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRL--WTV 300 LPTLRAATDP +GGQY+GPDGFGE RG+PKVV SSAQSHD+ LQRRL W + Sbjct 241 LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLPSWRI 293 >gi|108797576|ref|YP_637773.1| short chain dehydrogenase [Mycobacterium sp. MCS] gi|119866663|ref|YP_936615.1| short chain dehydrogenase [Mycobacterium sp. KMS] gi|108767995|gb|ABG06717.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS] gi|119692752|gb|ABL89825.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS] Length=306 Score = 414 bits (1063), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 222/312 (72%), Positives = 250/312 (81%), Gaps = 7/312 (2%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M+AN KW+AADVPDQ GRV V+TGANTGIGY AAV A +GAHVVLAVRN +KG A Sbjct 1 MSANT----KWTAADVPDQEGRVAVITGANTGIGYEAAAVLAAKGAHVVLAVRNTDKGGA 56 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A RI +A P A VT+++LDL SLDS+R AAD LR YPRID+LINNAGVM T K TKD Sbjct 57 AAERIRSALPHADVTVRELDLTSLDSIREAADGLRADYPRIDLLINNAGVMMTEKGATKD 116 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQ GTNHLGHFALTG +LD++LPV GSRVVTVSS HR ++FDDLQ ER YNRV Sbjct 117 GFELQLGTNHLGHFALTGQLLDNLLPVEGSRVVTVSSNAHR-WGRVNFDDLQSERSYNRV 175 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNL-PRLIRPVATVLGP 239 AYGQ+KLANLLFTYEL RRL G TIAVAAHPG S+TELTRNL P RPV V G Sbjct 176 TAYGQSKLANLLFTYELNRRLSAKGAPTIAVAAHPGTSSTELTRNLWPVARRPVELVWG- 234 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 L+ Q+PEMGALPTLRAATDP +GGQYYGPDG GEQRGHPK+VQS+A+S+D+ QRRLW+ Sbjct 235 LVAQTPEMGALPTLRAATDPDVRGGQYYGPDGIGEQRGHPKLVQSNARSYDEAAQRRLWS 294 Query 300 VSEELTGVSFGV 311 VSEELTGV+F V Sbjct 295 VSEELTGVTFPV 306 >gi|126433208|ref|YP_001068899.1| short chain dehydrogenase [Mycobacterium sp. JLS] gi|126233008|gb|ABN96408.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS] Length=300 Score = 413 bits (1061), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 210/302 (70%), Positives = 239/302 (80%), Gaps = 8/302 (2%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ AD+P QSGR VVTGANTG+G TA A RGAHVVLAVR+ EKG A I AA Sbjct 3 KWTTADIPSQSGRTAVVTGANTGLGLETAKALAARGAHVVLAVRDTEKGKRAADEIAAAH 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 P A V++Q LDL SL SVRAAA+AL+ +PRID+LINNAGVM+ PKQ T+DGFEL FGTN Sbjct 63 PEAAVSVQSLDLGSLRSVRAAAEALKADFPRIDLLINNAGVMYPPKQTTEDGFELTFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+L+++L P SRVVTVSSQGHRI AAIHFDDLQWER Y+RV AYGQ+KL+ Sbjct 123 HLGHFALTGLLLENVLAAPNSRVVTVSSQGHRIRAAIHFDDLQWERSYSRVGAYGQSKLS 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTR--NLPRLIRPVATVLGPLLFQSPEM 247 NLLFTYELQRRL + IAVAAHPG SNTEL R +LP + P+ VL QSP M Sbjct 183 NLLFTYELQRRLDT--RDAIAVAAHPGVSNTELMRHLHLPSVFNPLVGVLT----QSPTM 236 Query 248 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGV 307 GALPTLRAATDPT +GGQY+GP G GE RG+P++V SSAQS D DL RRLWTVSEELTGV Sbjct 237 GALPTLRAATDPTVRGGQYFGPSGLGEIRGYPELVTSSAQSRDVDLARRLWTVSEELTGV 296 Query 308 SF 309 +F Sbjct 297 AF 298 >gi|126433199|ref|YP_001068890.1| short chain dehydrogenase [Mycobacterium sp. JLS] gi|126232999|gb|ABN96399.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS] Length=306 Score = 412 bits (1058), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 222/312 (72%), Positives = 250/312 (81%), Gaps = 7/312 (2%) Query 1 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNA 60 M+AN KW+AADVPDQ GRV V+TGANTGIGY AAV A +GAHVVLAVRN +KG A Sbjct 1 MSANT----KWTAADVPDQEGRVAVITGANTGIGYEAAAVLAAKGAHVVLAVRNTDKGGA 56 Query 61 ARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKD 120 A RI +A P A VT+++LDL SLDS+RAAAD LR YPRID+LINNAGVM T K TKD Sbjct 57 AAERIRSALPHADVTVRELDLTSLDSIRAAADGLRADYPRIDLLINNAGVMMTQKGTTKD 116 Query 121 GFELQFGTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRV 180 GFELQ GTNHLGHFALTG +LD++LPV GSRVVTVSS HR ++FDDLQ ER YNRV Sbjct 117 GFELQLGTNHLGHFALTGQLLDNLLPVEGSRVVTVSSNAHR-WGRVNFDDLQSERSYNRV 175 Query 181 AAYGQAKLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNL-PRLIRPVATVLGP 239 AYGQ+KLANLLFTYEL RRL G TIAVAAHPG S+TELTRNL P RPV V G Sbjct 176 TAYGQSKLANLLFTYELNRRLSAKGAPTIAVAAHPGTSSTELTRNLWPVARRPVELVWG- 234 Query 240 LLFQSPEMGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWT 299 L+ Q+PEMGALPTLRAATDP +GGQYYGPDG GEQRGHPK+VQS+A+S+D+ QR LW+ Sbjct 235 LVSQTPEMGALPTLRAATDPDVRGGQYYGPDGIGEQRGHPKLVQSNARSYDEAAQRGLWS 294 Query 300 VSEELTGVSFGV 311 VSEELTGV+F V Sbjct 295 VSEELTGVTFPV 306 >gi|108797585|ref|YP_637782.1| short chain dehydrogenase [Mycobacterium sp. MCS] gi|119866672|ref|YP_936624.1| short chain dehydrogenase [Mycobacterium sp. KMS] gi|108768004|gb|ABG06726.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS] gi|119692761|gb|ABL89834.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS] Length=300 Score = 409 bits (1051), Expect = 3e-112, Method: Compositional matrix adjust. Identities = 209/300 (70%), Positives = 237/300 (79%), Gaps = 4/300 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ AD+P QSGR VVTGANTG+G TA A RGAHVVLAVR+ EKG A I AA Sbjct 3 KWTTADIPSQSGRTAVVTGANTGLGLETAKALAARGAHVVLAVRDTEKGKRAADEITAAH 62 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 P A V +Q LDL SL SVR AA+AL+ +PRID+LINNAGVM+ PKQ T+DGFEL FGTN Sbjct 63 PEAAVGVQSLDLGSLRSVRTAAEALKADFPRIDLLINNAGVMYPPKQTTEDGFELTFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+L+++L P SRVVTVSSQGHRI AAIHFDDLQWER Y+RV AYGQ+KL+ Sbjct 123 HLGHFALTGLLLENVLAAPNSRVVTVSSQGHRIRAAIHFDDLQWERSYSRVGAYGQSKLS 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NLLFTYELQRRL + IAVAAHPG SNTEL R+L + PV L +L QSP MGA Sbjct 183 NLLFTYELQRRLDT--RDAIAVAAHPGVSNTELMRHLH--LPPVFNPLVGVLTQSPTMGA 238 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDPT +GGQY+GP G GE RG+P++V SSAQS D DL RRLWTVSEELTGV+F Sbjct 239 LPTLRAATDPTVRGGQYFGPSGLGEIRGYPELVTSSAQSRDVDLARRLWTVSEELTGVAF 298 >gi|152966739|ref|YP_001362523.1| short chain dehydrogenase [Kineococcus radiotolerans SRS30216] gi|151361256|gb|ABS04259.1| short-chain dehydrogenase/reductase SDR [Kineococcus radiotolerans SRS30216] Length=304 Score = 405 bits (1042), Expect = 3e-111, Method: Compositional matrix adjust. Identities = 204/300 (68%), Positives = 237/300 (79%), Gaps = 1/300 (0%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+A VPDQSGRV VVTGANTG+G TA A+RGA VVLAVR+++KG A A + Sbjct 4 NWTARHVPDQSGRVAVVTGANTGLGLETARTLAERGATVVLAVRDVDKGARAAAGLTGNA 63 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 PG +V +Q+LDL SL+S+RAAA ALR A+PRID+L+NNAGVM+TP+Q T+DGFE QFGTN Sbjct 64 PG-NVVVQRLDLSSLESIRAAASALRDAHPRIDLLVNNAGVMYTPRQTTRDGFERQFGTN 122 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+L+ MLPVPGSRVVTVSS GHRI AAI FDDLQ ER Y+R AAYGQ+KLA Sbjct 123 HLGHFALTGLLLERMLPVPGSRVVTVSSTGHRIRAAIRFDDLQGERSYSRAAAYGQSKLA 182 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTYELQRRL G +T+AVAAHPG +NTEL RN P +R L PLL Q MGA Sbjct 183 NLMFTYELQRRLAAHGTTTVAVAAHPGVANTELVRNSPAAVRAAVDRLAPLLTQPAAMGA 242 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP+ GGQYYGP G GE RG+P++V SS QS+D QRRLW VS+ELTGV F Sbjct 243 LPTLRAATDPSVLGGQYYGPGGRGEVRGYPRLVTSSPQSYDLADQRRLWAVSQELTGVEF 302 >gi|326330990|ref|ZP_08197289.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae bacterium Broad-1] gi|325951201|gb|EGD43242.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae bacterium Broad-1] Length=301 Score = 405 bits (1040), Expect = 6e-111, Method: Compositional matrix adjust. Identities = 203/302 (68%), Positives = 236/302 (79%), Gaps = 6/302 (1%) Query 8 TRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMA 67 + W+ +PDQ GRV VVTGANTG+G+ TA + A+RGA VV+AVR++EKG A ARI Sbjct 2 SETWTEQHIPDQHGRVAVVTGANTGLGFETARMLAERGAQVVMAVRDVEKGKQAAARI-- 59 Query 68 ARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFG 127 VT+Q LDL SLDS+R+AA LR ++PRID+LINNAGVM+TPKQ T DGFE+QFG Sbjct 60 ---DGDVTVQVLDLASLDSIRSAAADLRASHPRIDLLINNAGVMYTPKQTTADGFEMQFG 116 Query 128 TNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAK 187 TNHLGHFA TGL+LD +LPVPGSR+VTVSS GHRI A IHFDDLQWER Y+RVAAYGQAK Sbjct 117 TNHLGHFAFTGLLLDQLLPVPGSRIVTVSSVGHRIRADIHFDDLQWERSYSRVAAYGQAK 176 Query 188 LANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEM 247 LANL+FTYELQRRL G +T+AVAAHPGGSNTEL RN P +R ++GPLL QS M Sbjct 177 LANLMFTYELQRRLAPHG-TTVAVAAHPGGSNTELARNSPAALRVPFALVGPLLAQSAAM 235 Query 248 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGV 307 GALPTL AATDP GGQYYGP G GE RG+PK+V SS S+D Q+RLW VSE+LT V Sbjct 236 GALPTLCAATDPAVIGGQYYGPSGRGEIRGYPKLVTSSPASYDLATQQRLWAVSEQLTDV 295 Query 308 SF 309 F Sbjct 296 RF 297 >gi|344999238|ref|YP_004802092.1| short-chain dehydrogenase/reductase SDR [Streptomyces sp. SirexAA-E] gi|344314864|gb|AEN09552.1| short-chain dehydrogenase/reductase SDR [Streptomyces sp. SirexAA-E] Length=307 Score = 402 bits (1033), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 213/300 (71%), Positives = 240/300 (80%), Gaps = 6/300 (2%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 +W+ D+PDQ GRV VVTGANTG+G+ TA + A RGA VVLAVR++EKG A AR+ Sbjct 4 EWTEQDIPDQRGRVAVVTGANTGLGFETARMLAARGAAVVLAVRDVEKGRRAAARLTG-- 61 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 VT+Q LDL SLDS+R+AA LR A+PRID+LINNAGVM+TP+Q T DGFELQFGTN Sbjct 62 ---DVTVQALDLTSLDSIRSAAADLRAAHPRIDLLINNAGVMYTPRQTTADGFELQFGTN 118 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+R AAYGQAKLA Sbjct 119 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIRAAIHFDDLQWERSYSRTAAYGQAKLA 178 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTYELQRRL G +T+AVAAHPG SNTEL RN P +R T L PLL Q EMGA Sbjct 179 NLMFTYELQRRLAPHG-TTVAVAAHPGVSNTELARNTPAALRVPITWLAPLLTQKAEMGA 237 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GGQYYGP G GE RG+PK V SS SHD+ +QRRLWTVSEELTGV+F Sbjct 238 LPTLRAATDPAVIGGQYYGPGGRGEIRGYPKPVTSSPDSHDQAVQRRLWTVSEELTGVTF 297 >gi|345014089|ref|YP_004816443.1| short-chain dehydrogenase/reductase SDR [Streptomyces violaceusniger Tu 4113] gi|344040438|gb|AEM86163.1| short-chain dehydrogenase/reductase SDR [Streptomyces violaceusniger Tu 4113] Length=307 Score = 401 bits (1031), Expect = 7e-110, Method: Compositional matrix adjust. Identities = 213/300 (71%), Positives = 238/300 (80%), Gaps = 6/300 (2%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ +PDQ GRV +VTGANTG+G+ TA + A RGA VVLAVR++EKG A ARI Sbjct 4 NWTEQHIPDQHGRVAIVTGANTGLGFETARMLAARGAAVVLAVRDVEKGKQAAARITG-- 61 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 VT+Q LDL SLDSVR+AA LR A+PRID+LINNAGVM+TP+Q T DGFELQFGTN Sbjct 62 ---DVTVQALDLASLDSVRSAAADLRAAHPRIDLLINNAGVMYTPRQTTADGFELQFGTN 118 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+RVAAYGQAKLA Sbjct 119 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIRAAIHFDDLQWERSYSRVAAYGQAKLA 178 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTYELQRRL G +T+AVAAHPG SNTEL RN P +R T L PLL Q EMGA Sbjct 179 NLMFTYELQRRLAPHG-TTVAVAAHPGVSNTELARNTPAALRVPVTWLAPLLTQKAEMGA 237 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GGQYYGP GE RG+PK+V SS SHD+ QRRLWTVSEELTGV+F Sbjct 238 LPTLRAATDPAVTGGQYYGPGNRGEIRGYPKLVASSPDSHDQAAQRRLWTVSEELTGVTF 297 >gi|169627749|ref|YP_001701398.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169239716|emb|CAM60744.1| Putative short-chain dehydrogenase/reductase [Mycobacterium abscessus] Length=307 Score = 399 bits (1025), Expect = 3e-109, Method: Compositional matrix adjust. Identities = 215/305 (71%), Positives = 242/305 (80%), Gaps = 2/305 (0%) Query 7 KTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIM 66 T KWS D+PDQ+GR+ +VTGANTG+G TA A GAHVVLAVRN EKG AA I Sbjct 4 STTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAEAIT 63 Query 67 AARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQF 126 AA A VTLQ LDL SL+SVR A+D L+ Y +ID+LINNAGVMWT K T DGFELQF Sbjct 64 AAHSNADVTLQSLDLSSLESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFELQF 123 Query 127 GTNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQA 186 GTNHLGH+ALTGL+L+ +LPV GSRVVTVSS GHRI A IHFDDLQWER Y+RVAAYGQ+ Sbjct 124 GTNHLGHYALTGLLLERLLPVEGSRVVTVSSIGHRIRADIHFDDLQWERDYDRVAAYGQS 183 Query 187 KLANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPE 246 KLANLLFTYELQRRL AG +T+A+AAHPGGSNTEL RN P +R V V+ P+L Q + Sbjct 184 KLANLLFTYELQRRL--AGTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGAD 241 Query 247 MGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTG 306 MGALPTLRAATDP GGQYYGPDGF EQRG+PKVV SS QS++ DLQRRLW+VSEELT Sbjct 242 MGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWSVSEELTD 301 Query 307 VSFGV 311 V F V Sbjct 302 VVFPV 306 >gi|315442299|ref|YP_004075178.1| hypothetical protein Mspyr1_06380 [Mycobacterium sp. Spyr1] gi|315260602|gb|ADT97343.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [Mycobacterium sp. Spyr1] Length=303 Score = 392 bits (1007), Expect = 4e-107, Method: Compositional matrix adjust. Identities = 195/301 (65%), Positives = 231/301 (77%), Gaps = 7/301 (2%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ AD+PDQ+GR V+TGANTG+G+ TA A++GA VV+AVRN +KG A ARI Sbjct 6 NWNVADIPDQTGRTAVITGANTGLGFETAKALAEKGARVVIAVRNTDKGAQAAARIRG-- 63 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 V +Q+LDL SL S+R AA+AL+ + +ID+LINNAGVM TPK T DGFELQFGTN Sbjct 64 ---DVDVQELDLTSLSSIRTAAEALKARFDKIDLLINNAGVMTTPKGTTADGFELQFGTN 120 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+ D++L +PGSR+VTVSS GH++ AIH+DDLQWER YNR+ AY Q+KLA Sbjct 121 HLGHFALTGLLFDNILDIPGSRIVTVSSNGHKMGGAIHWDDLQWERSYNRMGAYTQSKLA 180 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLF-QSPEMG 248 NLLFTYELQRRL GK TIAVAAHPG S TEL RNLPR + P+LF Q+ + G Sbjct 181 NLLFTYELQRRLAPRGK-TIAVAAHPGTSTTELARNLPRPVERAFLAAAPVLFAQTADRG 239 Query 249 ALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVS 308 ALPTLRAATDP GGQYYGPDG G+QRG P VV SSAQS+D D QRRLW +SEELT V+ Sbjct 240 ALPTLRAATDPGVLGGQYYGPDGLGQQRGAPVVVASSAQSYDVDQQRRLWEISEELTKVT 299 Query 309 F 309 F Sbjct 300 F 300 >gi|318062505|ref|ZP_07981226.1| short chain dehydrogenase [Streptomyces sp. SA3_actG] Length=301 Score = 391 bits (1005), Expect = 6e-107, Method: Compositional matrix adjust. Identities = 209/302 (70%), Positives = 231/302 (77%), Gaps = 6/302 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ DVPDQ GRV +VTGANTG+G+ TA A RGA VVLAVR+ KG A ARI Sbjct 5 NWTEQDVPDQRGRVAIVTGANTGLGFETARTLAARGAKVVLAVRDAGKGKQAAARI---- 60 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 VT+Q LDL SLDSVR+AA LR A+PRID+LINNAGVM+TPK+ T DGFELQFGTN Sbjct 61 -AGDVTVQTLDLTSLDSVRSAAAELREAHPRIDLLINNAGVMYTPKRTTADGFELQFGTN 119 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+R AYGQ+KLA Sbjct 120 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIRAAIHFDDLQWERAYSRTGAYGQSKLA 179 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTY LQRRL +T+A AAHPG SNTEL RN P +R T L PLL Q PEMGA Sbjct 180 NLMFTYALQRRLARH-STTVATAAHPGVSNTELIRNTPAPLRLPVTWLAPLLTQKPEMGA 238 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GG YYGP G GE RG PK V SS SHD+ +Q RLWTVSEELTGV+F Sbjct 239 LPTLRAATDPAANGGDYYGPGGMGELRGTPKRVASSPASHDEAVQERLWTVSEELTGVTF 298 Query 310 GV 311 V Sbjct 299 PV 300 >gi|302519700|ref|ZP_07272042.1| light-dependent protochlorophyllide reductase [Streptomyces sp. SPB78] gi|302428595|gb|EFL00411.1| light-dependent protochlorophyllide reductase [Streptomyces sp. SPB78] Length=301 Score = 391 bits (1004), Expect = 9e-107, Method: Compositional matrix adjust. Identities = 209/302 (70%), Positives = 231/302 (77%), Gaps = 6/302 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ DVPDQ GRV +VTGANTG+G+ TA A RGA VVLAVR+ KG A ARI Sbjct 5 NWTEQDVPDQRGRVAIVTGANTGLGFETARTLAARGAKVVLAVRDAGKGKQAAARI---- 60 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 VT+Q LDL SLDSVR+AA LR A+PRID+LINNAGVM+TPK+ T DGFELQFGTN Sbjct 61 -AGDVTVQTLDLTSLDSVRSAAAELREAHPRIDLLINNAGVMYTPKRTTADGFELQFGTN 119 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+R AYGQ+KLA Sbjct 120 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIRAAIHFDDLQWERAYSRTGAYGQSKLA 179 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTY LQRRL +T+A AAHPG SNTEL RN P +R T L PLL Q PEMGA Sbjct 180 NLMFTYALQRRLARH-STTVATAAHPGVSNTELIRNTPAPLRLPVTWLAPLLTQKPEMGA 238 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GG YYGP G GE RG PK V SS SHD+ +Q RLWTVSEELTGV+F Sbjct 239 LPTLRAATDPAANGGDYYGPGGMGELRGTPKRVASSPASHDEAVQERLWTVSEELTGVTF 298 Query 310 GV 311 V Sbjct 299 PV 300 >gi|145220748|ref|YP_001131426.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|145213234|gb|ABP42638.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum PYR-GCK] Length=303 Score = 390 bits (1001), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 194/301 (65%), Positives = 230/301 (77%), Gaps = 7/301 (2%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ AD+PDQ+GR V+TGANTG+G+ TA A++GA VV+AVRN +KG A ARI Sbjct 6 NWNVADIPDQTGRTAVITGANTGLGFETAKALAEKGARVVIAVRNTDKGAQAAARIRG-- 63 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 V +Q+LDL SL S+R AA+AL+ + +ID+LINNAGVM TPK T DGFELQFGTN Sbjct 64 ---DVDVQELDLTSLSSIRTAAEALKARFDKIDLLINNAGVMTTPKGTTADGFELQFGTN 120 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+ D++L +PGSR+VTVSS GH++ AIH+DDLQWER YNR+ AY Q+KLA Sbjct 121 HLGHFALTGLLFDNILDIPGSRIVTVSSNGHKMGGAIHWDDLQWERSYNRMGAYTQSKLA 180 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLF-QSPEMG 248 NLLFTYELQRRL GK TIAVAAHPG S TEL RNLPR + P+LF Q+ + G Sbjct 181 NLLFTYELQRRLAPRGK-TIAVAAHPGTSTTELARNLPRPVERAFLAAAPVLFAQTADRG 239 Query 249 ALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVS 308 ALPTLRAA DP GGQYYGPDG G+QRG P VV SSAQS+D D QRRLW +SEELT V+ Sbjct 240 ALPTLRAAADPGVLGGQYYGPDGLGQQRGAPVVVASSAQSYDVDQQRRLWEISEELTKVT 299 Query 309 F 309 F Sbjct 300 F 300 >gi|329940849|ref|ZP_08290129.1| putative oxidoreductase [Streptomyces griseoaurantiacus M045] gi|329300143|gb|EGG44041.1| putative oxidoreductase [Streptomyces griseoaurantiacus M045] Length=306 Score = 389 bits (1000), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 203/302 (68%), Positives = 236/302 (79%), Gaps = 6/302 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 KW+ +PDQ GRV +VTGANTG+G+ TA A RGAHVVLAVRN+EKG A RI Sbjct 4 KWTERHIPDQHGRVAIVTGANTGLGFETARALAARGAHVVLAVRNVEKGRQAADRI---- 59 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 V +Q LDL SLDS+R+AA LR A+PRID+LINNAGVM+TP++ T DGFELQF TN Sbjct 60 -DGRVDVQVLDLTSLDSIRSAAAELRAAHPRIDLLINNAGVMYTPRETTVDGFELQFATN 118 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+RV AYGQAKLA Sbjct 119 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIKAAIHFDDLQWERSYSRVGAYGQAKLA 178 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTYEL RRL G +T AVAAHPG SNT+L RN P ++R +L P+L Q MGA Sbjct 179 NLMFTYELNRRLAARG-TTSAVAAHPGVSNTDLMRNAPAVLRVPVNLLAPVLIQKSAMGA 237 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP +GG+YYGP GE RGHP+ V+SS +SH++ +QRRLW VSEELTGV+F Sbjct 238 LPTLRAATDPAVRGGEYYGPGNRGETRGHPRRVESSPESHEEAVQRRLWAVSEELTGVTF 297 Query 310 GV 311 V Sbjct 298 PV 299 >gi|333026481|ref|ZP_08454545.1| putative short chain dehydrogenase [Streptomyces sp. Tu6071] gi|332746333|gb|EGJ76774.1| putative short chain dehydrogenase [Streptomyces sp. Tu6071] Length=301 Score = 389 bits (1000), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 208/302 (69%), Positives = 232/302 (77%), Gaps = 6/302 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ DVP+Q GRV +VTGANTG+G+ TA A RGA VVLAVR+ KG A AAR Sbjct 5 NWTEQDVPEQRGRVAIVTGANTGLGFETARTLAARGAKVVLAVRDAGKGKQA-----AAR 59 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 VT+Q LDL SLDSVR+AA LR A+PRID+LINNAGVM+TPK+ T DGFELQFGTN Sbjct 60 MAGDVTVQTLDLTSLDSVRSAAAELREAHPRIDLLINNAGVMYTPKRTTADGFELQFGTN 119 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+R AYGQ+KLA Sbjct 120 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIRAAIHFDDLQWERAYSRTGAYGQSKLA 179 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTY LQRRL G +T+A AAHPG SNTEL RN P +R T L PLL Q PEMGA Sbjct 180 NLMFTYALQRRLARQG-TTVATAAHPGVSNTELIRNTPAPLRLPVTWLAPLLTQKPEMGA 238 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSF 309 LPTLRAATDP GG YYGP G GE RG PK V SS SHD+ +Q RLWTVSE+LTGV+F Sbjct 239 LPTLRAATDPAANGGDYYGPGGMGELRGTPKRVASSPASHDEAVQERLWTVSEKLTGVTF 298 Query 310 GV 311 V Sbjct 299 PV 300 >gi|120401777|ref|YP_951606.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119954595|gb|ABM11600.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii PYR-1] Length=302 Score = 385 bits (990), Expect = 3e-105, Method: Compositional matrix adjust. Identities = 201/301 (67%), Positives = 234/301 (78%), Gaps = 6/301 (1%) Query 11 WSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAARP 70 W+ AD+PDQ+GR V+TGANTG+G+ TA A GA VVLAVR+ EKG A AA+ Sbjct 4 WTTADIPDQTGRTAVITGANTGLGFETAKALAAGGARVVLAVRDTEKGAQA-----AAKM 58 Query 71 GAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTNH 130 V +QQLDL SL S+R+AADAL++ + ID+LINNAGVM TPK T DGFELQFGTNH Sbjct 59 AGDVDVQQLDLTSLASIRSAADALKSRFDHIDLLINNAGVMTTPKGTTADGFELQFGTNH 118 Query 131 LGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLAN 190 LGHFA TGL+LD +L V G+R+VTVSS GH++ AIH+DDLQWER Y+R+ AY Q+KLAN Sbjct 119 LGHFAFTGLLLDKLLDVDGARIVTVSSNGHKMGGAIHWDDLQWERSYSRMGAYSQSKLAN 178 Query 191 LLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGAL 250 LLFTYELQRRL GK TIAVAAHPG S+TEL RNLP ++P L PLL QSP GAL Sbjct 179 LLFTYELQRRLAPRGK-TIAVAAHPGTSSTELGRNLPAALQPALNRLAPLLAQSPAAGAL 237 Query 251 PTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSFG 310 PTLRAATDP+ GGQYYGPDG G+QRG+P VV SS QS+D LQRRLWTVSEELTGV+F Sbjct 238 PTLRAATDPSVLGGQYYGPDGIGQQRGNPVVVASSNQSYDMALQRRLWTVSEELTGVTFP 297 Query 311 V 311 V Sbjct 298 V 298 >gi|169627746|ref|YP_001701395.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169239713|emb|CAM60741.1| Putative short-chain dehydrogenase/reductase [Mycobacterium abscessus] Length=304 Score = 385 bits (988), Expect = 5e-105, Method: Compositional matrix adjust. Identities = 200/305 (66%), Positives = 232/305 (77%), Gaps = 3/305 (0%) Query 8 TRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMA 67 T W+ AD+PDQ+GRV VVTGANTG+G TA A GA VVLAVR+ +KG AA I Sbjct 2 TVHWTTADIPDQTGRVAVVTGANTGLGLETARALAAAGAQVVLAVRDPDKGAAAADDITK 61 Query 68 ARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFG 127 G+++ LQ+LDL SL +R+AA L YPRID+LINNAGVM+ PK +T DGFELQFG Sbjct 62 GAAGSNLALQRLDLSSLSDIRSAARQLGADYPRIDLLINNAGVMYPPKSLTADGFELQFG 121 Query 128 TNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAK 187 TNHLGHFALTGL+L+++ VP SRVV VSS GH+ AAIHFDDLQWER Y+RV AY Q+K Sbjct 122 TNHLGHFALTGLLLENLTAVPDSRVVIVSSNGHKFRAAIHFDDLQWERGYSRVGAYAQSK 181 Query 188 LANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPL-LFQSPE 246 LANLLFTYELQRRL AG T+A+AAHPG S TEL R++ P A L + QSP Sbjct 182 LANLLFTYELQRRLQAAGAETVALAAHPGASGTELMRHI--TFGPEALTAAALKIAQSPA 239 Query 247 MGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTG 306 MGALP+LRAATDP QGGQYYGP GFGE RG+PKVV+SS QSHDK LQ+RLW+VSEELTG Sbjct 240 MGALPSLRAATDPAAQGGQYYGPSGFGEFRGYPKVVRSSKQSHDKVLQQRLWSVSEELTG 299 Query 307 VSFGV 311 V F V Sbjct 300 VRFPV 304 >gi|318081453|ref|ZP_07988779.1| short chain dehydrogenase [Streptomyces sp. SA3_actF] Length=294 Score = 384 bits (985), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 205/296 (70%), Positives = 226/296 (77%), Gaps = 6/296 (2%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ DVPDQ GRV +VTGANTG+G+ TA A RGA VVLAVR+ KG A ARI Sbjct 5 NWTEQDVPDQRGRVAIVTGANTGLGFETARTLAARGAKVVLAVRDAGKGKQAAARI---- 60 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 VT+Q LDL SLDSVR+AA LR A+PRID+LINNAGVM+TPK+ T DGFELQFGTN Sbjct 61 -AGDVTVQTLDLTSLDSVRSAAAELREAHPRIDLLINNAGVMYTPKRTTADGFELQFGTN 119 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFALTGL+LD +LPVPGSRVVTVSS GHRI AAIHFDDLQWER Y+R AYGQ+KLA Sbjct 120 HLGHFALTGLLLDRLLPVPGSRVVTVSSTGHRIRAAIHFDDLQWERAYSRTGAYGQSKLA 179 Query 190 NLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGA 249 NL+FTY LQRRL +T+A AAHPG SNTEL RN P +R T L PLL Q PEMGA Sbjct 180 NLMFTYALQRRLARH-STTVATAAHPGVSNTELIRNTPAPLRLPVTWLAPLLTQKPEMGA 238 Query 250 LPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELT 305 LPTLRAATDP GG YYGP G GE RG PK V SS SHD+ +Q RLWTVSEELT Sbjct 239 LPTLRAATDPAANGGDYYGPGGMGELRGTPKRVASSPASHDEAVQERLWTVSEELT 294 >gi|120401768|ref|YP_951597.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119954586|gb|ABM11591.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii PYR-1] Length=305 Score = 380 bits (977), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 210/302 (70%), Positives = 237/302 (79%), Gaps = 0/302 (0%) Query 8 TRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMA 67 + KW+AADVPDQSGRV VVTGAN+GIGY AAV A RGA VV+AVRNL+KG A +RI Sbjct 2 SSKWTAADVPDQSGRVAVVTGANSGIGYEAAAVLAGRGARVVVAVRNLDKGRQAVSRIRQ 61 Query 68 ARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFG 127 PGA V LQ+LDL SL SVRAAAD LR A+PRID+LINNAGVM+ PKQ T DGFELQFG Sbjct 62 LHPGADVMLQELDLSSLASVRAAADDLRAAHPRIDLLINNAGVMYPPKQTTSDGFELQFG 121 Query 128 TNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAK 187 TNHLGHFALTGL+LD +LPV GSRVV+V+S H I A IHFDDLQWER YNRVAAYGQ+K Sbjct 122 TNHLGHFALTGLLLDRLLPVEGSRVVSVASIAHNIQADIHFDDLQWERSYNRVAAYGQSK 181 Query 188 LANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEM 247 LANL+FTY L RRL G TIAVAAHPG SNTEL R++P P L L+ SP + Sbjct 182 LANLMFTYTLARRLAAKGAPTIAVAAHPGISNTELMRHIPGSQLPGFAWLAGLVTNSPAV 241 Query 248 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGV 307 G+L TLRAATDP +GGQYYGP G E GHP +VQS+ +SHD D+Q RLWTVSEELTGV Sbjct 242 GSLATLRAATDPGVRGGQYYGPSGVRELVGHPVLVQSNRKSHDVDVQERLWTVSEELTGV 301 Query 308 SF 309 S+ Sbjct 302 SY 303 >gi|315506558|ref|YP_004085445.1| short-chain dehydrogenase/reductase sdr [Micromonospora sp. L5] gi|315413177|gb|ADU11294.1| short-chain dehydrogenase/reductase SDR [Micromonospora sp. L5] Length=314 Score = 379 bits (972), Expect = 4e-103, Method: Compositional matrix adjust. Identities = 202/301 (68%), Positives = 236/301 (79%), Gaps = 6/301 (1%) Query 11 WSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAARP 70 W+ AD+PDQ GRV VVTGANTG+GY TA A+RGA VVLAVR++ KG A A + Sbjct 5 WTTADIPDQRGRVAVVTGANTGLGYETAKALAERGASVVLAVRDVGKGERAAAGLTG--- 61 Query 71 GAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTNH 130 V++Q LDL SLDSVR AA ALR+ + RID+L+NNAGVM+TPK+ T+DGFELQFGTNH Sbjct 62 --DVSVQALDLTSLDSVRTAAAALRSRFGRIDLLVNNAGVMYTPKRTTRDGFELQFGTNH 119 Query 131 LGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLAN 190 LGHFALTGL+LD MLPVPGSRVVTVSS GHRI AAIHFDDL +ER Y R AAYGQ+KLAN Sbjct 120 LGHFALTGLLLDLMLPVPGSRVVTVSSTGHRIRAAIHFDDLHFERSYGRAAAYGQSKLAN 179 Query 191 LLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGAL 250 L+FTYELQRRL G +T+AVAAHPG S+TEL RN P +R T L PL+ Q+P MGAL Sbjct 180 LMFTYELQRRLAPYG-TTVAVAAHPGMSSTELARNTPAALRLPLTWLAPLITQTPAMGAL 238 Query 251 PTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSFG 310 PTLRAATDP GGQYYGP G E +GHP++V SS QS++ +Q+RLW VSE+LTGV F Sbjct 239 PTLRAATDPAVLGGQYYGPGGRYEVKGHPRLVTSSPQSYEVAVQQRLWAVSEDLTGVRFP 298 Query 311 V 311 V Sbjct 299 V 299 >gi|256377425|ref|YP_003101085.1| short chain dehydrogenase [Actinosynnema mirum DSM 43827] gi|255921728|gb|ACU37239.1| short-chain dehydrogenase/reductase SDR [Actinosynnema mirum DSM 43827] Length=299 Score = 379 bits (972), Expect = 5e-103, Method: Compositional matrix adjust. Identities = 207/304 (69%), Positives = 235/304 (78%), Gaps = 6/304 (1%) Query 8 TRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMA 67 T W+ VPDQ+GR VVTGANTG+G+ TA V A+RGA VVLAVR++EKG A RI Sbjct 2 TENWTEQHVPDQTGRTAVVTGANTGLGFETARVLAERGATVVLAVRDVEKGKRAADRI-- 59 Query 68 ARPGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFG 127 V +Q+LDL SLDSVR AA +LR A+PR+D+LINNAGVM+TP+ T+DGFELQFG Sbjct 60 ---AGEVLVQELDLTSLDSVREAAASLRAAHPRLDLLINNAGVMYTPRLTTRDGFELQFG 116 Query 128 TNHLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAK 187 TNHLGHFALTGL+L+ +LPVPGSRVVTVSS GHRI AAIHFDDL WER Y+R AYGQ+K Sbjct 117 TNHLGHFALTGLLLERLLPVPGSRVVTVSSTGHRIQAAIHFDDLHWERSYSRAGAYGQSK 176 Query 188 LANLLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEM 247 LANL+FTYELQRRL A +T AVAAHPG SNTEL RN P IR T L P+L Q M Sbjct 177 LANLMFTYELQRRL-AAHGATAAVAAHPGMSNTELARNTPAAIRVPVTWLAPVLTQPATM 235 Query 248 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGV 307 GALPTLRAATDP GGQYYGP G GE +GHP+VV SS QSHD ++QRRLW VSE LTGV Sbjct 236 GALPTLRAATDPAALGGQYYGPGGRGEVKGHPRVVASSPQSHDAEVQRRLWDVSERLTGV 295 Query 308 SFGV 311 F V Sbjct 296 VFPV 299 >gi|302867004|ref|YP_003835641.1| short-chain dehydrogenase/reductase SDR [Micromonospora aurantiaca ATCC 27029] gi|302569863|gb|ADL46065.1| short-chain dehydrogenase/reductase SDR [Micromonospora aurantiaca ATCC 27029] Length=314 Score = 378 bits (970), Expect = 7e-103, Method: Compositional matrix adjust. Identities = 202/301 (68%), Positives = 235/301 (79%), Gaps = 6/301 (1%) Query 11 WSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAARP 70 W+ AD+PDQ GRV VVTGANTG+GY TA A+RGA VVLAVR++ KG A A + Sbjct 5 WTTADIPDQRGRVAVVTGANTGLGYETAKALAERGASVVLAVRDVGKGERAAAGLTG--- 61 Query 71 GAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTNH 130 V++Q LDL SLDSVR AA ALR+ + RID+L+NNAGVM+TPK+ T+DGFELQFGTNH Sbjct 62 --DVSVQALDLTSLDSVRTAAAALRSRFGRIDLLVNNAGVMYTPKRTTRDGFELQFGTNH 119 Query 131 LGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLAN 190 LGHFALTGL+LD MLPVPGSRVVTVSS GHRI AAIHFDDL ER Y R AAYGQ+KLAN Sbjct 120 LGHFALTGLLLDLMLPVPGSRVVTVSSTGHRIRAAIHFDDLHSERSYGRAAAYGQSKLAN 179 Query 191 LLFTYELQRRLGEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPEMGAL 250 L+FTYELQRRL G +T+AVAAHPG S+TEL RN P +R T L PL+ Q+P MGAL Sbjct 180 LMFTYELQRRLAPYG-TTVAVAAHPGMSSTELARNTPAALRLPLTWLAPLITQTPAMGAL 238 Query 251 PTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTGVSFG 310 PTLRAATDP GGQYYGP G E +GHP++V SS QS++ +Q+RLW VSE+LTGV F Sbjct 239 PTLRAATDPAVLGGQYYGPGGRYEVKGHPRLVTSSPQSYEAAVQQRLWAVSEDLTGVRFP 298 Query 311 V 311 V Sbjct 299 V 299 >gi|296138583|ref|YP_003645826.1| short-chain dehydrogenase/reductase SDR [Tsukamurella paurometabola DSM 20162] gi|296026717|gb|ADG77487.1| short-chain dehydrogenase/reductase SDR [Tsukamurella paurometabola DSM 20162] Length=307 Score = 377 bits (969), Expect = 9e-103, Method: Compositional matrix adjust. Identities = 195/305 (64%), Positives = 226/305 (75%), Gaps = 4/305 (1%) Query 10 KWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAAR 69 W+ DVP Q GRV VVTG+NTG+G+ TA V A GA VVLAVR+ +KG AAR RI AA Sbjct 4 NWTERDVPTQQGRVAVVTGSNTGLGFETARVLAQAGAEVVLAVRDTDKGEAARQRITAAA 63 Query 70 PGAHVTLQQLDLCSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTN 129 P + V + +LDL SL+S+ AAA L + PR+D+LINNAGVM+ PKQ T DGFELQFGTN Sbjct 64 PESAVRVLRLDLGSLESIAAAATELHESTPRVDLLINNAGVMYPPKQSTADGFELQFGTN 123 Query 130 HLGHFALTGLVLDHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLA 189 HLGHFA T VLD +L VP SRVVTV+S HRI AAIHFDDLQWER Y RVAAYGQ+KLA Sbjct 124 HLGHFAWTAQVLDLLLDVPNSRVVTVASIAHRIRAAIHFDDLQWERSYERVAAYGQSKLA 183 Query 190 NLLFTYELQRRLG---EAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLFQSPE 246 NLLF YELQRRL A T+A+AAHPG ++TEL RNLPR ++ + PL Sbjct 184 NLLFHYELQRRLQARPRADHGTVAIAAHPGIADTELVRNLPRALQGLQAA-APLFSHDAA 242 Query 247 MGALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELTG 306 GALP LRAATDP GGQYYGPDG GE+RG P+VV SS QS+D DLQ RLW VSE+LTG Sbjct 243 HGALPQLRAATDPGALGGQYYGPDGLGERRGAPRVVTSSQQSYDLDLQHRLWAVSEQLTG 302 Query 307 VSFGV 311 ++F V Sbjct 303 IAFPV 307 Lambda K H 0.319 0.133 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 533708119992 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40