BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0446c

Length=256
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|254230794|ref|ZP_04924121.1|  hypothetical protein TBCG_00438 ...   504    5e-141
gi|15839834|ref|NP_334871.1|  hypothetical protein MT0462 [Mycoba...   503    9e-141
gi|15607587|ref|NP_214960.1|  transmembrane protein [Mycobacteriu...   503    1e-140
gi|289441825|ref|ZP_06431569.1|  conserved membrane protein [Myco...   503    1e-140
gi|289756520|ref|ZP_06515898.1|  LOW QUALITY PROTEIN: transmembra...   439    3e-121
gi|240169828|ref|ZP_04748487.1|  transmembrane protein [Mycobacte...   399    2e-109
gi|183980791|ref|YP_001849082.1|  transmembrane protein [Mycobact...   399    3e-109
gi|118617083|ref|YP_905415.1|  transmembrane protein [Mycobacteri...   396    2e-108
gi|148821643|ref|YP_001286397.1|  transmembrane protein [Mycobact...   336    2e-90 
gi|289552695|ref|ZP_06441905.1|  conserved membrane protein [Myco...   334    7e-90 
gi|167970736|ref|ZP_02553013.1|  hypothetical protein MtubH3_2295...   321    7e-86 
gi|262200135|ref|YP_003271343.1|  hypothetical protein Gbro_0099 ...   291    8e-77 
gi|111019552|ref|YP_702524.1|  hypothetical protein RHA1_ro02561 ...   287    1e-75 
gi|296141260|ref|YP_003648503.1|  hypothetical protein Tpau_3586 ...   280    1e-73 
gi|296392460|ref|YP_003657344.1|  hypothetical protein Srot_0020 ...   278    4e-73 
gi|226361702|ref|YP_002779480.1|  hypothetical protein ROP_22880 ...   277    1e-72 
gi|229491005|ref|ZP_04384838.1|  conserved hypothetical protein [...   276    2e-72 
gi|226305812|ref|YP_002765772.1|  hypothetical protein RER_23250 ...   275    4e-72 
gi|333920776|ref|YP_004494357.1|  hypothetical protein AS9A_3112 ...   256    3e-66 
gi|84497728|ref|ZP_00996550.1|  possible conserved transmembrane ...   249    4e-64 
gi|297560225|ref|YP_003679199.1|  hypothetical protein Ndas_1254 ...   239    2e-61 
gi|271964424|ref|YP_003338620.1|  hypothetical protein Sros_2922 ...   232    3e-59 
gi|226307984|ref|YP_002767944.1|  hypothetical protein RER_44970 ...   221    8e-56 
gi|328880441|emb|CCA53680.1|  Hypothetical protein SVEN_0393 [Str...   220    2e-55 
gi|229488720|ref|ZP_04382586.1|  conserved hypothetical protein [...   219    4e-55 
gi|311894085|dbj|BAJ26493.1|  hypothetical protein KSE_06530 [Kit...   216    2e-54 
gi|290955651|ref|YP_003486833.1|  hypothetical protein SCAB_10941...   216    3e-54 
gi|311743513|ref|ZP_07717319.1|  transmembrane protein [Aeromicro...   215    4e-54 
gi|182439674|ref|YP_001827393.1|  hypothetical protein SGR_5881 [...   215    6e-54 
gi|320011762|gb|ADW06612.1|  protein of unknown function DUF1295 ...   214    8e-54 
gi|311741881|ref|ZP_07715692.1|  transmembrane protein [Aeromicro...   214    9e-54 
gi|326780338|ref|ZP_08239603.1|  protein of unknown function DUF1...   213    2e-53 
gi|239986567|ref|ZP_04707231.1|  hypothetical protein SrosN1_0459...   213    2e-53 
gi|119718758|ref|YP_925723.1|  hypothetical protein Noca_4539 [No...   212    4e-53 
gi|344998663|ref|YP_004801517.1|  hypothetical protein SACTE_1051...   207    2e-51 
gi|167966530|ref|ZP_02548807.1|  hypothetical protein MtubH3_0006...   202    3e-50 
gi|256393408|ref|YP_003114972.1|  hypothetical protein Caci_4267 ...   199    4e-49 
gi|116669894|ref|YP_830827.1|  hypothetical protein Arth_1333 [Ar...   196    2e-48 
gi|331698463|ref|YP_004334702.1|  hypothetical protein Psed_4702 ...   196    4e-48 
gi|258655282|ref|YP_003204438.1|  hypothetical protein Namu_5181 ...   191    7e-47 
gi|154253342|ref|YP_001414166.1|  hypothetical protein Plav_2902 ...   188    7e-46 
gi|300784853|ref|YP_003765144.1|  hypothetical protein AMED_2949 ...   187    1e-45 
gi|254387382|ref|ZP_05002630.1|  conserved hypothetical protein [...   187    1e-45 
gi|302528461|ref|ZP_07280803.1|  conserved hypothetical protein [...   185    5e-45 
gi|254421083|ref|ZP_05034807.1|  conserved hypothetical protein [...   184    1e-44 
gi|302382141|ref|YP_003817964.1|  hypothetical protein Bresu_1029...   181    1e-43 
gi|87198584|ref|YP_495841.1|  hypothetical protein Saro_0560 [Nov...   178    6e-43 
gi|318057381|ref|ZP_07976104.1|  hypothetical protein SSA3_05541 ...   178    6e-43 
gi|325001851|ref|ZP_08122963.1|  hypothetical protein PseP1_23956...   177    2e-42 
gi|291453039|ref|ZP_06592429.1|  conserved hypothetical protein [...   176    3e-42 


>gi|254230794|ref|ZP_04924121.1| hypothetical protein TBCG_00438 [Mycobacterium tuberculosis C]
 gi|254363410|ref|ZP_04979456.1| conserved transmembrane protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|289744142|ref|ZP_06503520.1| transmembrane protein [Mycobacterium tuberculosis 02_1987]
 31 more sequence titles
 Length=260

 Score =  504 bits (1298),  Expect = 5e-141, Method: Compositional matrix adjust.
 Identities = 256/256 (100%), Positives = 256/256 (100%), Gaps = 0/256 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL
Sbjct  5    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  64

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL
Sbjct  65   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  124

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
            SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH
Sbjct  125  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  184

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ
Sbjct  185  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  244

Query  241  RRTAYFVPRPPRSARR  256
            RRTAYFVPRPPRSARR
Sbjct  245  RRTAYFVPRPPRSARR  260


>gi|15839834|ref|NP_334871.1| hypothetical protein MT0462 [Mycobacterium tuberculosis CDC1551]
 gi|13879967|gb|AAK44685.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
Length=269

 Score =  503 bits (1295),  Expect = 9e-141, Method: Compositional matrix adjust.
 Identities = 256/256 (100%), Positives = 256/256 (100%), Gaps = 0/256 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL
Sbjct  14   VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  73

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL
Sbjct  74   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  133

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
            SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH
Sbjct  134  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  193

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ
Sbjct  194  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  253

Query  241  RRTAYFVPRPPRSARR  256
            RRTAYFVPRPPRSARR
Sbjct  254  RRTAYFVPRPPRSARR  269


>gi|15607587|ref|NP_214960.1| transmembrane protein [Mycobacterium tuberculosis H37Rv]
 gi|31791624|ref|NP_854117.1| transmembrane protein [Mycobacterium bovis AF2122/97]
 gi|121636360|ref|YP_976583.1| putative transmembrane protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 21 more sequence titles
 Length=256

 Score =  503 bits (1295),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 255/256 (99%), Positives = 256/256 (100%), Gaps = 0/256 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +VTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL
Sbjct  1    MVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL
Sbjct  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
            SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH
Sbjct  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ
Sbjct  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240

Query  241  RRTAYFVPRPPRSARR  256
            RRTAYFVPRPPRSARR
Sbjct  241  RRTAYFVPRPPRSARR  256


>gi|289441825|ref|ZP_06431569.1| conserved membrane protein [Mycobacterium tuberculosis T46]
 gi|289568362|ref|ZP_06448589.1| conserved membrane protein [Mycobacterium tuberculosis T17]
 gi|289748930|ref|ZP_06508308.1| conserved membrane protein [Mycobacterium tuberculosis T92]
 gi|289414744|gb|EFD11984.1| conserved membrane protein [Mycobacterium tuberculosis T46]
 gi|289542115|gb|EFD45764.1| conserved membrane protein [Mycobacterium tuberculosis T17]
 gi|289689517|gb|EFD56946.1| conserved membrane protein [Mycobacterium tuberculosis T92]
Length=256

 Score =  503 bits (1294),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 254/256 (99%), Positives = 256/256 (100%), Gaps = 0/256 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +VTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL
Sbjct  1    MVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFP+QL
Sbjct  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPMQL  120

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
            SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH
Sbjct  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ
Sbjct  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240

Query  241  RRTAYFVPRPPRSARR  256
            RRTAYFVPRPPRSARR
Sbjct  241  RRTAYFVPRPPRSARR  256


>gi|289756520|ref|ZP_06515898.1| LOW QUALITY PROTEIN: transmembrane protein [Mycobacterium tuberculosis 
T85]
 gi|289712084|gb|EFD76096.1| LOW QUALITY PROTEIN: transmembrane protein [Mycobacterium tuberculosis 
T85]
Length=220

 Score =  439 bits (1128),  Expect = 3e-121, Method: Compositional matrix adjust.
 Identities = 220/220 (100%), Positives = 220/220 (100%), Gaps = 0/220 (0%)

Query  37   GFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATP  96
            GFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATP
Sbjct  1    GFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATP  60

Query  97   VQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQL  156
            VQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQL
Sbjct  61   VQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQL  120

Query  157  WVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYL  216
            WVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYL
Sbjct  121  WVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYL  180

Query  217  LVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR  256
            LVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR
Sbjct  181  LVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR  220


>gi|240169828|ref|ZP_04748487.1| transmembrane protein [Mycobacterium kansasii ATCC 12478]
Length=264

 Score =  399 bits (1026),  Expect = 2e-109, Method: Compositional matrix adjust.
 Identities = 201/244 (83%), Positives = 215/244 (89%), Gaps = 0/244 (0%)

Query  13   VHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSW  72
            VHS  F IGR +GRYNVVDV WGLGF+AVAV AA  G GDP RRWLLLALV+ WGLRLSW
Sbjct  20   VHSATFLIGRWLGRYNVVDVAWGLGFIAVAVVAAVFGTGDPARRWLLLALVTVWGLRLSW  79

Query  73   HMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLL  132
            HMYRKTAG+GEDPRYADLLRGAT  Q +RKVFGLQ  LTLF+SFPLQLSAVTGPTP+PLL
Sbjct  80   HMYRKTAGKGEDPRYADLLRGATTAQVVRKVFGLQAFLTLFISFPLQLSAVTGPTPRPLL  139

Query  133  AVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWG  192
            AV  VG+A+WLVG+ FEA+GD QL  FKSDPANRG IMDRGLWAWTRHPNYFGDACVWWG
Sbjct  140  AVTAVGVALWLVGLVFEALGDRQLRAFKSDPANRGAIMDRGLWAWTRHPNYFGDACVWWG  199

Query  193  LWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPR  252
            LWLITI  W PL TV SPLLMTY LVDVSGARLTE+Y+KGRPGFAEYQRRTAYFVPRPPR
Sbjct  200  LWLITITGWVPLLTVVSPLLMTYFLVDVSGARLTEKYMKGRPGFAEYQRRTAYFVPRPPR  259

Query  253  SARR  256
            SAR+
Sbjct  260  SARQ  263


>gi|183980791|ref|YP_001849082.1| transmembrane protein [Mycobacterium marinum M]
 gi|183174117|gb|ACC39227.1| conserved transmembrane protein [Mycobacterium marinum M]
Length=264

 Score =  399 bits (1024),  Expect = 3e-109, Method: Compositional matrix adjust.
 Identities = 199/256 (78%), Positives = 219/256 (86%), Gaps = 0/256 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +++  SA A+ VVHSV FAIG RIGRYNVVDV WGLGFVAVA  +A LG GDP RRWLLL
Sbjct  8    LISGASAAALIVVHSVTFAIGHRIGRYNVVDVAWGLGFVAVAAVSAVLGSGDPTRRWLLL  67

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
             LV+ WGLRLSWH++RKT G+GEDPRY DLLR AT  Q +RKVF LQ  LTLF+SFPLQL
Sbjct  68   TLVAIWGLRLSWHIHRKTVGKGEDPRYTDLLRDATLGQVVRKVFVLQAFLTLFISFPLQL  127

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
            SAVTGPTPKPLLAVG +G+AVWL+G+ FEA+GD QL  FK+DPANRG IMDRGLWAWTRH
Sbjct  128  SAVTGPTPKPLLAVGALGVAVWLLGVVFEALGDHQLRAFKADPANRGAIMDRGLWAWTRH  187

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDACVWWGLWL+TI  W PL TVGSPLLMTY LVDVSGARLTE+Y+K RPGF EYQ
Sbjct  188  PNYFGDACVWWGLWLVTITGWVPLITVGSPLLMTYFLVDVSGARLTEKYMKDRPGFGEYQ  247

Query  241  RRTAYFVPRPPRSARR  256
            RRTAYFVPRPPRSAR 
Sbjct  248  RRTAYFVPRPPRSARH  263


>gi|118617083|ref|YP_905415.1| transmembrane protein [Mycobacterium ulcerans Agy99]
 gi|118569193|gb|ABL03944.1| conserved transmembrane protein [Mycobacterium ulcerans Agy99]
Length=257

 Score =  396 bits (1017),  Expect = 2e-108, Method: Compositional matrix adjust.
 Identities = 199/256 (78%), Positives = 219/256 (86%), Gaps = 0/256 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +++  SA A+ VVHSV FAIG RIGRYNVVDV WGLGFVAVA  +A LG GDP RRWLLL
Sbjct  1    MISGASAAALIVVHSVTFAIGHRIGRYNVVDVAWGLGFVAVAAVSAVLGSGDPTRRWLLL  60

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALV+ WGLRLS H++RK  G+GEDPRY DLLRGAT  Q +RKVF LQ  LTLF+SFPLQL
Sbjct  61   ALVAIWGLRLSRHIHRKRVGKGEDPRYTDLLRGATLGQVVRKVFVLQAFLTLFISFPLQL  120

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
            SAVTGPTPKPLLAVG +G+AVWL+G+ FEA+GD QL  FK+DPANRG IMDRGLWAWTRH
Sbjct  121  SAVTGPTPKPLLAVGALGVAVWLLGVVFEALGDHQLRAFKADPANRGAIMDRGLWAWTRH  180

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDACVWWGLWL+TI  W PL TVGSPLLMTY LVDVSGARLTE+Y+K RPGF EYQ
Sbjct  181  PNYFGDACVWWGLWLVTITGWVPLITVGSPLLMTYFLVDVSGARLTEKYMKDRPGFGEYQ  240

Query  241  RRTAYFVPRPPRSARR  256
            RRTAYFVPRPPRSAR 
Sbjct  241  RRTAYFVPRPPRSARH  256


>gi|148821643|ref|YP_001286397.1| transmembrane protein [Mycobacterium tuberculosis F11]
 gi|253797371|ref|YP_003030372.1| hypothetical protein TBMG_00447 [Mycobacterium tuberculosis KZN 
1435]
 gi|289760562|ref|ZP_06519940.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|148720170|gb|ABR04795.1| conserved transmembrane protein [Mycobacterium tuberculosis F11]
 gi|253318874|gb|ACT23477.1| conserved membrane protein [Mycobacterium tuberculosis KZN 1435]
 gi|289708068|gb|EFD72084.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|328457157|gb|AEB02580.1| conserved membrane protein [Mycobacterium tuberculosis KZN 4207]
Length=178

 Score =  336 bits (861),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 174/174 (100%), Positives = 174/174 (100%), Gaps = 0/174 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL
Sbjct  5    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  64

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL
Sbjct  65   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  124

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL  174
            SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL
Sbjct  125  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL  178


>gi|289552695|ref|ZP_06441905.1| conserved membrane protein [Mycobacterium tuberculosis KZN 605]
 gi|289437327|gb|EFD19820.1| conserved membrane protein [Mycobacterium tuberculosis KZN 605]
 gi|344218262|gb|AEM98892.1| transmembrane protein [Mycobacterium tuberculosis CTRI-2]
Length=174

 Score =  334 bits (857),  Expect = 7e-90, Method: Compositional matrix adjust.
 Identities = 173/174 (99%), Positives = 174/174 (100%), Gaps = 0/174 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +VTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL
Sbjct  1    MVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120
            ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL
Sbjct  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQL  120

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL  174
            SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL
Sbjct  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL  174


>gi|167970736|ref|ZP_02553013.1| hypothetical protein MtubH3_22955 [Mycobacterium tuberculosis 
H37Ra]
Length=160

 Score =  321 bits (822),  Expect = 7e-86, Method: Compositional matrix adjust.
 Identities = 159/160 (99%), Positives = 160/160 (100%), Gaps = 0/160 (0%)

Query  97   VQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQL  156
            +QALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQL
Sbjct  1    MQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQL  60

Query  157  WVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYL  216
            WVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYL
Sbjct  61   WVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYL  120

Query  217  LVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR  256
            LVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR
Sbjct  121  LVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR  160


>gi|262200135|ref|YP_003271343.1| hypothetical protein Gbro_0099 [Gordonia bronchialis DSM 43247]
 gi|262083482|gb|ACY19450.1| protein of unknown function DUF1295 [Gordonia bronchialis DSM 
43247]
Length=267

 Score =  291 bits (744),  Expect = 8e-77, Method: Compositional matrix adjust.
 Identities = 145/254 (58%), Positives = 179/254 (71%), Gaps = 2/254 (0%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            V+T  + + +A + +VAFAIG RIGRYNVVDVVWGLGFV VA  A  LG GDP RRWL  
Sbjct  9    VLTVAALILLAAIQAVAFAIGHRIGRYNVVDVVWGLGFVGVAWLALLLGDGDPFRRWLFA  68

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLR--GATPVQALRKVFGLQGLLTLFVSFPL  118
             L + WGLRLSWHM+ K+ G+GEDPRY  +L   G      +RKVF  QG+   FVS P+
Sbjct  69   ILAAVWGLRLSWHMHVKSRGKGEDPRYTAMLERAGGGTGTVIRKVFATQGISQWFVSLPI  128

Query  119  QLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            Q+SA+ GP       +  +G+ +WL G  FEAVGD QL  FK+DPAN+G IMDRGLWAWT
Sbjct  129  QVSAILGPGDGVATILLCLGIPLWLTGFAFEAVGDAQLRRFKADPANKGAIMDRGLWAWT  188

Query  179  RHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAE  238
            RHPNYFGD+CVWWG++L     W    T+ SP+ MTY LV  +GARL E+ +  RPG+ E
Sbjct  189  RHPNYFGDSCVWWGIYLCAAGVWPATLTLLSPIAMTYFLVYATGARLLEQSMSKRPGYPE  248

Query  239  YQRRTAYFVPRPPR  252
            YQ+RT+YF+PRPPR
Sbjct  249  YQQRTSYFLPRPPR  262


>gi|111019552|ref|YP_702524.1| hypothetical protein RHA1_ro02561 [Rhodococcus jostii RHA1]
 gi|110819082|gb|ABG94366.1| possible membrane protein [Rhodococcus jostii RHA1]
Length=266

 Score =  287 bits (735),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 149/254 (59%), Positives = 188/254 (75%), Gaps = 3/254 (1%)

Query  2    VTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLA  61
            VT+ S L +AV  +  F +GRRIGRYNVVDV WGLGFV VA+ AA +G GD +RRWL++ 
Sbjct  12   VTAASLLVLAVFQAATFLVGRRIGRYNVVDVSWGLGFVLVALVAAVIGDGDALRRWLVVV  71

Query  62   LVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPL  118
            LV+ WGLRL+WHMY K+AG+GEDPRY ++L    G +P   +RK+F  QGL   FVS PL
Sbjct  72   LVAVWGLRLTWHMYAKSAGKGEDPRYVEMLDRAGGNSPWVVVRKIFLTQGLAQWFVSLPL  131

Query  119  QLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            Q+SAV GP       VG +G  +W+VG+ FEAVGD QL  FK+DP+N+G IMD GLWAWT
Sbjct  132  QVSAVLGPASGLGAVVGVLGALLWVVGVVFEAVGDHQLMAFKADPSNKGEIMDVGLWAWT  191

Query  179  RHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAE  238
            RHPNYFGD+CVWWGLWL+  + W    TV SP++MTY LV  +GARL E+ +  RPG+ E
Sbjct  192  RHPNYFGDSCVWWGLWLLAASVWPGAVTVLSPVVMTYFLVFATGARLLEKSMSQRPGYPE  251

Query  239  YQRRTAYFVPRPPR  252
            YQ+RT+YF+P PP+
Sbjct  252  YQQRTSYFLPLPPK  265


>gi|296141260|ref|YP_003648503.1| hypothetical protein Tpau_3586 [Tsukamurella paurometabola DSM 
20162]
 gi|296029394|gb|ADG80164.1| protein of unknown function DUF1295 [Tsukamurella paurometabola 
DSM 20162]
Length=264

 Score =  280 bits (717),  Expect = 1e-73, Method: Compositional matrix adjust.
 Identities = 154/259 (60%), Positives = 185/259 (72%), Gaps = 3/259 (1%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VVT+ S LA+A V ++ F +GR IGRYNVVDV WG G VAVA  A  LG GD +R  ++ 
Sbjct  6    VVTAWSVLALAAVQAITFTVGRAIGRYNVVDVAWGAGIVAVAWIALFLGDGDRIRGAVIT  65

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFP  117
            A+V+ WG+RLSWHM+ K+AG+GEDPRY DLL    G      +RK+F +QG    FVS P
Sbjct  66   AIVTVWGVRLSWHMWIKSAGKGEDPRYVDLLDRAGGGGIGTVIRKIFVVQGAAQWFVSLP  125

Query  118  LQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAW  177
            +Q+SAVTG T    L V   GLA  +VGI FEAVGD QL VFK+DPA+RG IMDRGLWAW
Sbjct  126  VQVSAVTGSTTGVALIVAAAGLAAAVVGIGFEAVGDHQLRVFKADPAHRGAIMDRGLWAW  185

Query  178  TRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFA  237
            TRHPNYFGDAC WWG+WLI  + W  + TV SP LMTY LV  +GARL ER++  RPG+ 
Sbjct  186  TRHPNYFGDACTWWGVWLIAASAWPGVLTVASPALMTYFLVHATGARLLERFMSQRPGWD  245

Query  238  EYQRRTAYFVPRPPRSARR  256
            EY  RT++FVP PPR  RR
Sbjct  246  EYAARTSFFVPLPPRRERR  264


>gi|296392460|ref|YP_003657344.1| hypothetical protein Srot_0020 [Segniliparus rotundus DSM 44985]
 gi|296179607|gb|ADG96513.1| protein of unknown function DUF1295 [Segniliparus rotundus DSM 
44985]
Length=264

 Score =  278 bits (712),  Expect = 4e-73, Method: Compositional matrix adjust.
 Identities = 144/236 (62%), Positives = 172/236 (73%), Gaps = 3/236 (1%)

Query  21   GRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAG  80
            GR+IGRYNVVDV WGLGF   A  AA +G GD  RR L  AL++ WGLRLSWHM+RK+AG
Sbjct  29   GRKIGRYNVVDVAWGLGFALAAAVAAAVGQGDLPRRVLFAALIALWGLRLSWHMHRKSAG  88

Query  81   QGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGV  137
            +GEDPRY  LL    GA+    + +VF +QGL   FVS P+QLSAV GPTP+        
Sbjct  89   RGEDPRYEALLERKGGASTWNIIVQVFVIQGLAQWFVSLPVQLSAVLGPTPRAFFPALVA  148

Query  138  GLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLIT  197
            G+ ++  G+ FEAVGDWQL  FKS+P NRG IMD GLW WTRHPNYFGD+CVWWGLWL +
Sbjct  149  GVGLYTAGVLFEAVGDWQLRAFKSNPDNRGRIMDVGLWRWTRHPNYFGDSCVWWGLWLCS  208

Query  198  INDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRS  253
            +   A LATV SP LMTY LV  +GARL ER++  RPG+ EYQ+RT++FVP PPRS
Sbjct  209  LACPASLATVLSPALMTYFLVHATGARLLERHMADRPGYREYQQRTSFFVPWPPRS  264


>gi|226361702|ref|YP_002779480.1| hypothetical protein ROP_22880 [Rhodococcus opacus B4]
 gi|226240187|dbj|BAH50535.1| hypothetical membrane protein [Rhodococcus opacus B4]
Length=266

 Score =  277 bits (708),  Expect = 1e-72, Method: Compositional matrix adjust.
 Identities = 150/254 (60%), Positives = 187/254 (74%), Gaps = 3/254 (1%)

Query  2    VTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLA  61
            VT  S L +AV+ +    +GRRIGRYNVVDV WGLGFV VA+ AA +G GD +RRWL L 
Sbjct  12   VTGASLLVLAVLQAATLLVGRRIGRYNVVDVTWGLGFVLVALVAAVVGDGDALRRWLALV  71

Query  62   LVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPL  118
            LV+ WGLRL+WHMY K+AG+GEDPRY ++L    G +P   +RK+F  QGL   FVS PL
Sbjct  72   LVAVWGLRLTWHMYVKSAGKGEDPRYEEMLDRAGGDSPGVVVRKIFLTQGLAQWFVSLPL  131

Query  119  QLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            Q+SAV GP     + V  +G+ +W+VG+ FE+VGD QL  FK+DPAN+G IMD GLWAWT
Sbjct  132  QVSAVVGPASGFAMVVAVLGVVLWVVGVVFESVGDHQLKKFKADPANKGEIMDVGLWAWT  191

Query  179  RHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAE  238
            RHPNYFGDACVWWGLWLI  + W    TV SP++MTY LV  +GARL E+ +  RPG+ E
Sbjct  192  RHPNYFGDACVWWGLWLIAASVWPGAVTVLSPVVMTYFLVFATGARLLEKSMSQRPGYPE  251

Query  239  YQRRTAYFVPRPPR  252
            YQ+RT+YF+P PP+
Sbjct  252  YQQRTSYFLPLPPK  265


>gi|229491005|ref|ZP_04384838.1| conserved hypothetical protein [Rhodococcus erythropolis SK121]
 gi|229322121|gb|EEN87909.1| conserved hypothetical protein [Rhodococcus erythropolis SK121]
Length=272

 Score =  276 bits (707),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 140/256 (55%), Positives = 191/256 (75%), Gaps = 6/256 (2%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VVT  S LA+AV  +V   IG RIGR+NVVDV WG GFV +A+ +A +G GD  RR L+L
Sbjct  16   VVTLTSLLAIAVGMAVTATIGVRIGRHNVVDVSWGAGFVLIALVSAIVGTGDLWRRLLML  75

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGAT---PVQALRKVFGLQGLLTLFVSFP  117
            ALV+ WGLRL+ HM  ++ G+GEDPRY ++L  AT    + A+RK++  QG+   FVS P
Sbjct  76   ALVAIWGLRLATHMAIRSRGKGEDPRYEEMLGRATGNRTLYAIRKIYLTQGISLWFVSLP  135

Query  118  LQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAW  177
            +Q++AV+  +   L+ +G   +A+W+VG+TFE VGD Q+  FKSDP +RG IMD+GLWAW
Sbjct  136  IQVAAVSNGSFGLLVVLG---IALWIVGVTFETVGDRQMEEFKSDPGSRGHIMDQGLWAW  192

Query  178  TRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFA  237
            TRHPNYFGDACVWWG++L++ + W  + TV SP+ MTY LV  +GARL ER+++ RPG+ 
Sbjct  193  TRHPNYFGDACVWWGIFLVSASVWPGVLTVLSPIAMTYFLVFATGARLLERHMEQRPGYR  252

Query  238  EYQRRTAYFVPRPPRS  253
            EYQ+RT+YF+PRPP++
Sbjct  253  EYQQRTSYFIPRPPKA  268


>gi|226305812|ref|YP_002765772.1| hypothetical protein RER_23250 [Rhodococcus erythropolis PR4]
 gi|226184929|dbj|BAH33033.1| conserved hypothetical membrane protein [Rhodococcus erythropolis 
PR4]
Length=267

 Score =  275 bits (704),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 139/256 (55%), Positives = 190/256 (75%), Gaps = 6/256 (2%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VVT  S LA+A   +V   IG RIGR+NVVDV WG GFV +A+ +A +G GD  RR L+L
Sbjct  11   VVTLTSLLAIAFGMAVTATIGVRIGRHNVVDVSWGAGFVLIALVSAIVGTGDLWRRLLML  70

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLL---RGATPVQALRKVFGLQGLLTLFVSFP  117
            ALV+ WGLRL+ HM  ++ G+GEDPRY ++L    G+  + ALRK++  QG+   FVS P
Sbjct  71   ALVAIWGLRLATHMAIRSRGKGEDPRYEEMLGRATGSRTLYALRKIYLTQGISLWFVSLP  130

Query  118  LQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAW  177
            +Q++AV+  +   L+ +G   +A+W+VG+TFE VGD Q+  FKSDP +RG IMD+GLWAW
Sbjct  131  IQVAAVSNGSFGLLVVLG---IALWIVGVTFETVGDRQMEEFKSDPGSRGHIMDQGLWAW  187

Query  178  TRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFA  237
            TRHPNYFGDACVWWG++L++ + W  + TV SP+ MTY LV  +GARL ER+++ RPG+ 
Sbjct  188  TRHPNYFGDACVWWGIFLVSASVWPGVLTVLSPIAMTYFLVFATGARLLERHMEQRPGYR  247

Query  238  EYQRRTAYFVPRPPRS  253
            EYQ+RT+YF+PRPP++
Sbjct  248  EYQQRTSYFIPRPPKA  263


>gi|333920776|ref|YP_004494357.1| hypothetical protein AS9A_3112 [Amycolicicoccus subflavus DQS3-9A1]
 gi|333482997|gb|AEF41557.1| hypothetical protein AS9A_3112 [Amycolicicoccus subflavus DQS3-9A1]
Length=264

 Score =  256 bits (653),  Expect = 3e-66, Method: Compositional matrix adjust.
 Identities = 133/259 (52%), Positives = 185/259 (72%), Gaps = 6/259 (2%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            VV++ S  A+AV+ +V    G R+GR+NVVDV WGL FV+VA AAA  G G+P RR ++L
Sbjct  6    VVSAASLAAIAVLIAVTAVAGFRVGRHNVVDVSWGLAFVSVAAAAAAAGSGEPARRLVVL  65

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFP  117
             LV+ WG+RL+WHM+ +T G GEDPRY ++L+   G     A+RK++  Q L   FVS P
Sbjct  66   VLVTVWGVRLAWHMFIRTRGHGEDPRYTEMLQRGSGNPTWLAIRKIYLTQALAAWFVSLP  125

Query  118  LQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAW  177
            +Q++AV+     PL  +   G+ +W++G+TFEAVGD+QL  FK+DPANRG +MDRGLW+W
Sbjct  126  IQVAAVSD---GPLGWIAFAGILLWIMGLTFEAVGDYQLRKFKADPANRGKVMDRGLWSW  182

Query  178  TRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFA  237
            TRHPNYFGDACVWWG++LI  + W  + T+ SP+LMTY L   +G +L E+++  RPG+ 
Sbjct  183  TRHPNYFGDACVWWGIFLIAADVWPGVLTILSPVLMTYFLAFATGGKLLEKHMSERPGYR  242

Query  238  EYQRRTAYFVPRPPRSARR  256
            +YQ R ++FVP PP+   R
Sbjct  243  DYQARVSFFVPLPPKRKNR  261


>gi|84497728|ref|ZP_00996550.1| possible conserved transmembrane protein [Janibacter sp. HTCC2649]
 gi|84382616|gb|EAP98498.1| possible conserved transmembrane protein [Janibacter sp. HTCC2649]
Length=260

 Score =  249 bits (635),  Expect = 4e-64, Method: Compositional matrix adjust.
 Identities = 133/258 (52%), Positives = 171/258 (67%), Gaps = 8/258 (3%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +VT    +A AVV  V   I RR+G+ +VVD+ WGL FV +A        G   R  LL 
Sbjct  6    LVTLSCLVAAAVVMGVTALIARRLGKVSVVDIAWGLVFVVIAWVCTFFSPG--ARSLLLA  63

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQ----ALRKVFGLQGLLTLFVSF  116
             LV+ WG+RL+WH+ R+  G  EDPRY  LL  A P +    A+R+VF +QGL    VS 
Sbjct  64   VLVTVWGVRLAWHIRRRALGADEDPRYEKLLSAAPPEKRFGYAVRRVFVVQGLAAWVVSL  123

Query  117  PLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWA  176
            PLQ++A  G   KPL  V  +G+A+++VG+ FEA+GD QL  FKSDPAN+G IMDRGLWA
Sbjct  124  PLQVAAAAGA--KPLGWVAALGVALFVVGVGFEAIGDAQLARFKSDPANKGKIMDRGLWA  181

Query  177  WTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGF  236
            WTRHPNYFGDA VWWGLW+I+   W  + TV SP++MTY L   +GARL E  +  RPG+
Sbjct  182  WTRHPNYFGDAAVWWGLWVISAEVWPAVLTVFSPVIMTYFLAFATGARLLESEMSKRPGY  241

Query  237  AEYQRRTAYFVPRPPRSA  254
            +EY +RT+ F PRPPR +
Sbjct  242  SEYMQRTSMFFPRPPRQS  259


>gi|297560225|ref|YP_003679199.1| hypothetical protein Ndas_1254 [Nocardiopsis dassonvillei subsp. 
dassonvillei DSM 43111]
 gi|296844673|gb|ADH66693.1| protein of unknown function DUF1295 [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
Length=267

 Score =  239 bits (611),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 133/255 (53%), Positives = 167/255 (66%), Gaps = 10/255 (3%)

Query  5    VSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVS  64
            +SA AV  +    FA+  R+GR++VVD  WGLGF AVA        GDP R WLL  L +
Sbjct  12   LSAPAVLALMLATFALALRLGRHSVVDAAWGLGFTAVAAVGVLTASGDPARSWLLAGLTA  71

Query  65   TWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLS  121
             WG+RL+ H+  ++ G+GEDPRY  LL    G     ALR V+ LQG L   V+ P+Q +
Sbjct  72   VWGVRLAVHIGLRSRGRGEDPRYERLLDRAPGNRNAYALRVVYLLQGFLVWLVAMPVQAA  131

Query  122  AVTGP----TPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAW  177
              TG     +P+  LAV G   AVWL+G  FE VGD QL  F+ DPAN G IMDRGLWAW
Sbjct  132  VHTGAPLLGSPQVWLAVAGA--AVWLLGFVFETVGDAQLARFRRDPANSGRIMDRGLWAW  189

Query  178  TRHPNYFGDACVWWGLWLITIN-DWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGF  236
            TRHPNYFGDACVWWGL+L+ ++  W  L T+ +P++MTYLL   SG RL + ++ GRPG+
Sbjct  190  TRHPNYFGDACVWWGLFLVALSGSWWVLLTLPAPVVMTYLLTRGSGQRLLDEHMAGRPGW  249

Query  237  AEYQRRTAYFVPRPP  251
            AEY RRT+ FVP PP
Sbjct  250  AEYARRTSAFVPTPP  264


>gi|271964424|ref|YP_003338620.1| hypothetical protein Sros_2922 [Streptosporangium roseum DSM 
43021]
 gi|270507599|gb|ACZ85877.1| conserved hypothetical protein [Streptosporangium roseum DSM 
43021]
Length=264

 Score =  232 bits (592),  Expect = 3e-59, Method: Compositional matrix adjust.
 Identities = 120/236 (51%), Positives = 159/236 (68%), Gaps = 7/236 (2%)

Query  23   RIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQG  82
            R+GR++V+DV WGLGF  VA+ +     GDP RR L+L L + WG+RL+ H+ R+  G+G
Sbjct  31   RVGRHSVIDVAWGLGFTVVALVSYASSGGDPARRLLVLVLTAAWGVRLAAHIGRRNIGEG  90

Query  83   EDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGL  139
            EDPRY  +L    G+  + ALR V+  QG   LFVS P+Q++      P PL  V   G+
Sbjct  91   EDPRYERMLARAPGSRTLYALRAVYLTQGAALLFVSLPVQVAMFE---PGPLGRVAWTGV  147

Query  140  AVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITIN  199
            A+WLVG  FE VGDWQL  F++DP +RG ++D GLW +TRHPNYFGDACVWWGL+L+  +
Sbjct  148  ALWLVGAFFETVGDWQLARFRADPGSRGKVLDTGLWRYTRHPNYFGDACVWWGLFLVAAD  207

Query  200  DWAPLATVGSPLLMTYLLVDVSGARLTERYLKG-RPGFAEYQRRTAYFVPRPPRSA  254
             W  + TV SP+LMTY L   +G  + ER L G RPG+A+Y RRT+ F P PPR +
Sbjct  208  QWPGVLTVLSPVLMTYFLAGKTGKPMLERQLSGSRPGYADYVRRTSGFFPLPPRKS  263


>gi|226307984|ref|YP_002767944.1| hypothetical protein RER_44970 [Rhodococcus erythropolis PR4]
 gi|226187101|dbj|BAH35205.1| conserved hypothetical membrane protein [Rhodococcus erythropolis 
PR4]
Length=274

 Score =  221 bits (563),  Expect = 8e-56, Method: Compositional matrix adjust.
 Identities = 120/260 (47%), Positives = 168/260 (65%), Gaps = 11/260 (4%)

Query  5    VSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAA--ATLG-HGDPVRRWLLLA  61
            VSALAV V  +V  A+  R+  ++++D+ WG GF  VAV +   ++G  G+ +RR ++LA
Sbjct  15   VSALAVLVFIAVVMAVAIRMNNHSIIDICWGPGFAVVAVVSYLTSIGSDGNDLRRLVVLA  74

Query  62   LVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPL  118
            L   WG+RL  ++  +  G G+D RY  LL+   G      +RK++GLQG+L L VS P+
Sbjct  75   LTVVWGMRLGLYIGFRNRGHGQDKRYTALLKHQQGPLIPFLIRKIYGLQGVLILVVSLPV  134

Query  119  QLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            Q +       + L  +G +G+AVW VG  FE+VGD+QL  FK+DPAN G++MDRGLWAWT
Sbjct  135  QFAMYEF---RALGVLGAIGIAVWTVGFVFESVGDYQLSRFKADPANSGMVMDRGLWAWT  191

Query  179  RHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPG--F  236
            RHPNYFGDACVW GL+++ + D   L T+ SP++M  LLV  SG  L ER ++   G  +
Sbjct  192  RHPNYFGDACVWVGLFILALGDPLALITIVSPIVMIKLLVSYSGKALLERGMRKSKGQAY  251

Query  237  AEYQRRTAYFVPRPPRSARR  256
             +Y  RT+ F PRPPR AR 
Sbjct  252  DDYVARTSGFFPRPPRPARN  271


>gi|328880441|emb|CCA53680.1| Hypothetical protein SVEN_0393 [Streptomyces venezuelae ATCC 
10712]
Length=276

 Score =  220 bits (560),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 121/245 (50%), Positives = 153/245 (63%), Gaps = 9/245 (3%)

Query  18   FAIGRRIGRYNVVDVVWGLGFVAVAVAA--ATLGHGDPVRRWLLLALVSTWGLRLSWHMY  75
            FA+  R G + +VD+ WGL F AVAV     + GHGD  RR L  A    WGLRL+ H+ 
Sbjct  28   FAVAVRRGLHRIVDIAWGLAFSAVAVVTWLLSAGHGDDGRRLLAAAATVLWGLRLAAHIA  87

Query  76   RKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLL  132
            R++ G GEDPRY  LL    G   + ALR V+  Q  L   +S P+Q ++ +     PL 
Sbjct  88   RRSRGHGEDPRYTALLAKAPGNRTLYALRTVYLGQAALVWLISLPVQAASYSS---APLD  144

Query  133  AVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWG  192
                 G+A+W +G+ FEAVGD QL  FK DPANRG IMD+GLWAWTRHPNYFGD+ VWWG
Sbjct  145  LPAFCGIALWALGLAFEAVGDHQLACFKQDPANRGRIMDKGLWAWTRHPNYFGDSLVWWG  204

Query  193  LWLITINDWAP-LATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPP  251
            L+++    W P L  + SP+LMT LL   SG RL E+++ GRPG+A Y  RT+ F P PP
Sbjct  205  LYVLACTAWQPALIVLVSPVLMTALLTVGSGKRLLEKHMSGRPGYAAYAARTSGFFPLPP  264

Query  252  RSARR  256
            R   R
Sbjct  265  RRTAR  269


>gi|229488720|ref|ZP_04382586.1| conserved hypothetical protein [Rhodococcus erythropolis SK121]
 gi|229324224|gb|EEN89979.1| conserved hypothetical protein [Rhodococcus erythropolis SK121]
Length=274

 Score =  219 bits (557),  Expect = 4e-55, Method: Compositional matrix adjust.
 Identities = 119/260 (46%), Positives = 167/260 (65%), Gaps = 11/260 (4%)

Query  5    VSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAA--ATLG-HGDPVRRWLLLA  61
            VSALAV V  +V  A+  R+  ++++D+ WG GF  VA  +   ++G  G+ +RR ++LA
Sbjct  15   VSALAVLVFIAVVMAVAIRMNNHSIIDICWGPGFAVVAAVSYLTSIGSDGNDLRRLVVLA  74

Query  62   LVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPL  118
            L   WG+RL  ++  +  G G+D RY  LL+   G      +RK++GLQG+L L VS P+
Sbjct  75   LTVVWGMRLGLYIGFRNRGHGQDKRYTALLKHQQGPLVPFLIRKIYGLQGVLILVVSLPV  134

Query  119  QLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            Q +       + L  +G +G+AVW VG  FE+VGD+QL  FK+DPAN G +MDRGLWAWT
Sbjct  135  QFAMYEF---RALGVLGAIGIAVWTVGFVFESVGDYQLSRFKADPANAGKVMDRGLWAWT  191

Query  179  RHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPG--F  236
            RHPNYFGDACVW GL+++ + D   L T+ SP++M  LLV  SG  L ER ++   G  +
Sbjct  192  RHPNYFGDACVWVGLFILALGDPLALITIVSPIVMIKLLVSYSGKALLERGMRKSKGQAY  251

Query  237  AEYQRRTAYFVPRPPRSARR  256
             +Y  RT+ F+PRPPR AR 
Sbjct  252  DDYVARTSGFLPRPPRPARN  271


>gi|311894085|dbj|BAJ26493.1| hypothetical protein KSE_06530 [Kitasatospora setae KM-6054]
Length=272

 Score =  216 bits (551),  Expect = 2e-54, Method: Compositional matrix adjust.
 Identities = 134/253 (53%), Positives = 163/253 (65%), Gaps = 12/253 (4%)

Query  12   VVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLR  69
             V  +AFA+G R GR+  VD  WGL F AVA+    L  G+GD  RR L  ALV+ WGLR
Sbjct  19   TVMLLAFAVGLRTGRHRDVDTAWGLAFTAVALTGCGLSAGYGDDGRRALATALVTVWGLR  78

Query  70   LSWHMYRKTAGQGEDPRYADLLRGAT--PVQ---ALRKVFGLQGLLTLFVSFPLQLSAVT  124
            L+ H++ +  G  EDPRYA +L  A   P +   ALR V+ LQ  L  FV+ P+ L+A  
Sbjct  79   LAAHLWWRARGLPEDPRYARMLAKAPAGPARTRYALRIVYLLQAALVWFVALPV-LAAQY  137

Query  125  GPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYF  184
             PTP    A  G   A+W VG+ FEAVGD QL  FK+DPANRG +MDRGLW WTRHPNYF
Sbjct  138  QPTPPGPTAWAGT--ALWAVGLFFEAVGDAQLARFKADPANRGRVMDRGLWRWTRHPNYF  195

Query  185  GDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYL--KGRPGFAEYQRR  242
            GDACVWWGL+L+  +  A    VGSPLLMT+LL   SG  + ER+L    RPG+AEY  R
Sbjct  196  GDACVWWGLFLLAADTPAGWLFVGSPLLMTWLLAFGSGKPMLERHLATTERPGWAEYTAR  255

Query  243  TAYFVPRPPRSAR  255
            T+ F+P PPR  R
Sbjct  256  TSSFLPLPPRRHR  268


>gi|290955651|ref|YP_003486833.1| hypothetical protein SCAB_10941 [Streptomyces scabiei 87.22]
 gi|260645177|emb|CBG68263.1| POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN [Streptomyces scabiei 
87.22]
Length=270

 Score =  216 bits (550),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 130/258 (51%), Positives = 158/258 (62%), Gaps = 11/258 (4%)

Query  6    SALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL----GHGDPVRRWLLLA  61
            SA A   V  V FA+  R+G + +VD+ WGLGF  VAV +         GDPVRR L  A
Sbjct  9    SAAAALTVMLVTFALAVRVGLHRIVDIAWGLGFTVVAVVSFAASAAQDEGDPVRRLLATA  68

Query  62   LVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGAT---PVQALRKVFGLQGLLTLFVSFPL  118
            L + WGLRL+ H+ R+  G GEDPRY  +L  AT    V ALR V+ LQG L   VS P+
Sbjct  69   LTAAWGLRLAVHIARRGRGHGEDPRYEAMLAKATGNRNVYALRMVYLLQGALVWLVSLPV  128

Query  119  QLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            Q +      P  L A  G GL  W VG+ FEAVGD QL  FK+    RG IMDRGLWAWT
Sbjct  129  QAAQYVPGRPSAL-AWAGAGL--WAVGLCFEAVGDAQLARFKAGAEGRGRIMDRGLWAWT  185

Query  179  RHPNYFGDACVWWGLWLITIND-WAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFA  237
            RHPNYFGD CVWWGL+LI      A   +V SP++M+ LL+  SG RL ER++  RPG+A
Sbjct  186  RHPNYFGDFCVWWGLFLIACGSPGAAAVSVASPVVMSLLLIRGSGKRLLERHMADRPGYA  245

Query  238  EYQRRTAYFVPRPPRSAR  255
            +Y  RT+ F P PP+  R
Sbjct  246  DYVARTSGFFPLPPKRRR  263


>gi|311743513|ref|ZP_07717319.1| transmembrane protein [Aeromicrobium marinum DSM 15272]
 gi|311312643|gb|EFQ82554.1| transmembrane protein [Aeromicrobium marinum DSM 15272]
Length=267

 Score =  215 bits (548),  Expect = 4e-54, Method: Compositional matrix adjust.
 Identities = 118/251 (48%), Positives = 162/251 (65%), Gaps = 10/251 (3%)

Query  10   VAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL---GHGDPVRRWLLLALVSTW  66
            V  + +    + R   +  VVD +WGLGFVAVA+A+  +   G GDPV RW+LLA+ + W
Sbjct  19   VVALMTTGLLLARAQQKLTVVDTLWGLGFVAVAIASTAVSFAGDGDPVVRWILLAMTAVW  78

Query  67   GLRLSWHMYRKTAGQGEDPRYADLLRG---ATPVQALRKVFGLQGLLTLFVSFPLQLSAV  123
            GLRL+ +++R+  GQ EDPRYA+L      +    A+ +VF  QG+    V+ PL +   
Sbjct  79   GLRLAIYLHRRNHGQAEDPRYAELAEADGRSFSRVAISRVFLPQGIAMFLVATPLMVGV-  137

Query  124  TGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNY  183
               T  P+ A+   G+ VW VG+ FEAVGD QL  FK+DPAN+G +MD+GLW +TRHPNY
Sbjct  138  --NTEDPVWALVVAGVVVWAVGLFFEAVGDAQLAAFKADPANKGQVMDQGLWRYTRHPNY  195

Query  184  FGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRR  242
            FGDACVW G+WL+  + W  LAT  SP+ MT  L  V+GA L E+ + K +PG+ EY RR
Sbjct  196  FGDACVWTGIWLVAASSWVGLATAISPIAMTVFLTKVTGASLNEKGMRKTKPGYEEYVRR  255

Query  243  TAYFVPRPPRS  253
            T+ F+P PP+ 
Sbjct  256  TSGFIPLPPKK  266


>gi|182439674|ref|YP_001827393.1| hypothetical protein SGR_5881 [Streptomyces griseus subsp. griseus 
NBRC 13350]
 gi|178468190|dbj|BAG22710.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus 
NBRC 13350]
Length=267

 Score =  215 bits (547),  Expect = 6e-54, Method: Compositional matrix adjust.
 Identities = 126/243 (52%), Positives = 157/243 (65%), Gaps = 9/243 (3%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLRLSWH  73
            V FA+  R G + +VDV WG+GF AVA+ + +L  G GD VRR L+ AL   WGLRL+ H
Sbjct  26   VTFAVALRKGVHRIVDVAWGIGFAAVALVSYSLSAGEGDDVRRLLVTALTVIWGLRLAIH  85

Query  74   MYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKP  130
            + R+  G GEDPRY  +L    G   + ALRKV+ LQG L   VS P+Q +        P
Sbjct  86   IGRRGKGHGEDPRYEKMLAKAPGNPQLYALRKVYLLQGALVWLVSLPVQAAQYL---TAP  142

Query  131  LLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVW  190
            L      G+ +W VG+ FEA+GD QL  FK+DPAN+G IMDRGLW+WTRHPNYFGD CVW
Sbjct  143  LAPWAWAGVLLWAVGLAFEAIGDAQLARFKADPANKGKIMDRGLWSWTRHPNYFGDFCVW  202

Query  191  WGLWLITIN-DWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPR  249
            WGL+L       A  ATV +PL+M++LL   SGA L ER++  RPGF  Y  RT+ F PR
Sbjct  203  WGLFLFVCQAPAAAAATVVAPLVMSFLLTRGSGAALLERHMADRPGFDAYVARTSGFFPR  262

Query  250  PPR  252
            PPR
Sbjct  263  PPR  265


>gi|320011762|gb|ADW06612.1| protein of unknown function DUF1295 [Streptomyces flavogriseus 
ATCC 33331]
Length=268

 Score =  214 bits (546),  Expect = 8e-54, Method: Compositional matrix adjust.
 Identities = 130/244 (54%), Positives = 159/244 (66%), Gaps = 10/244 (4%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL---GHGDPVRRWLLLALVSTWGLRLSW  72
            V F I  R   + +VDV WGLGF AVA+A+  +   G GD  RR LL  L + WG+RL+ 
Sbjct  26   VTFLIALRKRVHRIVDVAWGLGFAAVALASYVMSADGDGDQGRRLLLTVLTAVWGVRLAV  85

Query  73   HMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPK  129
            H+ R+  G GEDPRYA +L    G   + ALRKV+ LQG L   +S P+Q        P 
Sbjct  86   HIGRRGRGHGEDPRYAAMLAKAPGHPDLYALRKVYLLQGALVWLISLPVQAGYYL---PG  142

Query  130  PLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACV  189
            PL A    G AVW VG+ FEAVGD QL  FK DPAN+G IMDRGLW+WTRHPNYFGD CV
Sbjct  143  PLDAWAWAGAAVWAVGLAFEAVGDAQLARFKRDPANKGRIMDRGLWSWTRHPNYFGDFCV  202

Query  190  WWGLWLITINDWAPLA-TVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVP  248
            WWGL+L+   D A  A T+ SP++M+ LL   SG  L ER+++GRPG+AEY  RT+ F P
Sbjct  203  WWGLFLVVCADPAVAATTLVSPVVMSLLLTKGSGKALLERHMEGRPGYAEYLARTSGFFP  262

Query  249  RPPR  252
            RPPR
Sbjct  263  RPPR  266


>gi|311741881|ref|ZP_07715692.1| transmembrane protein [Aeromicrobium marinum DSM 15272]
 gi|311314887|gb|EFQ84793.1| transmembrane protein [Aeromicrobium marinum DSM 15272]
Length=276

 Score =  214 bits (546),  Expect = 9e-54, Method: Compositional matrix adjust.
 Identities = 116/245 (48%), Positives = 155/245 (64%), Gaps = 11/245 (4%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLG---HGDPVRRWLLLALVSTWGLRLSW  72
            V  A   R+   +++D+ WG GFV VAV +  +     GD  RR ++LAL S WGLRL  
Sbjct  26   VIMAAAIRLKNQSIIDIFWGPGFVVVAVVSYLMSMGSEGDDARRLVVLALTSVWGLRLGL  85

Query  73   HMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPK  129
            ++  +  G GED RY  ++R   GA     +R+++GLQG L L VS P+Q +       +
Sbjct  86   YIGNRNRGHGEDRRYTSMMRQRKGALIPFLIRRIYGLQGFLILLVSVPVQFAMYQ---SQ  142

Query  130  PLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACV  189
             +  VG +G+A+WLVG TFEAVGD QL  FK+DPAN G +MD GLW +TRHPNYFGDACV
Sbjct  143  AIGVVGSIGIAIWLVGFTFEAVGDAQLKRFKADPANEGKVMDGGLWKYTRHPNYFGDACV  202

Query  190  WWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPG--FAEYQRRTAYFV  247
            W GL+L+ +     L T+ SP++MT LLV  SGA + ER +K R G  + +Y  RT+ F 
Sbjct  203  WVGLFLLALGSPVGLITIVSPIVMTKLLVSYSGAAVLERGMKRRRGQAYEDYIARTSGFF  262

Query  248  PRPPR  252
            PRPPR
Sbjct  263  PRPPR  267


>gi|326780338|ref|ZP_08239603.1| protein of unknown function DUF1295 [Streptomyces cf. griseus 
XylebKG-1]
 gi|326660671|gb|EGE45517.1| protein of unknown function DUF1295 [Streptomyces griseus XylebKG-1]
Length=267

 Score =  213 bits (543),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 126/243 (52%), Positives = 156/243 (65%), Gaps = 9/243 (3%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLRLSWH  73
            V FA+  R G + +VDV WG+GF AVA+ +  L  G GD VRR L+ AL   WGLRL+ H
Sbjct  26   VTFAVALRKGVHRIVDVAWGIGFAAVALVSYGLSAGEGDDVRRLLVTALTVIWGLRLAIH  85

Query  74   MYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKP  130
            + R+  G GEDPRY  +L    G   + ALRKV+ LQG L   VS P+Q +        P
Sbjct  86   IGRRGKGHGEDPRYEKMLAKAPGNPQLYALRKVYLLQGALVWLVSLPVQAAQYL---TAP  142

Query  131  LLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVW  190
            L      G+ +W VG+ FEA+GD QL  FK+DPAN+G IMDRGLW+WTRHPNYFGD CVW
Sbjct  143  LAPWAWAGVLLWAVGLAFEAIGDAQLARFKADPANKGKIMDRGLWSWTRHPNYFGDFCVW  202

Query  191  WGLWLITIN-DWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPR  249
            WGL+L       A  ATV +PL+M++LL   SGA L ER++  RPGF  Y  RT+ F PR
Sbjct  203  WGLFLFVCQAPAAAAATVVAPLVMSFLLTRGSGAALLERHMADRPGFDAYVARTSGFFPR  262

Query  250  PPR  252
            PPR
Sbjct  263  PPR  265


>gi|239986567|ref|ZP_04707231.1| hypothetical protein SrosN1_04595 [Streptomyces roseosporus NRRL 
11379]
 gi|291443507|ref|ZP_06582897.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 
15998]
 gi|291346454|gb|EFE73358.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 
15998]
Length=267

 Score =  213 bits (543),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 126/245 (52%), Positives = 158/245 (65%), Gaps = 9/245 (3%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLRLSWH  73
            V FA+    G + +VD+ WGLGF  VA+ +  L  G GD  RR L+ AL   WGLRL+ H
Sbjct  26   VTFAVALNKGVHRIVDIAWGLGFAVVALVSYGLSAGVGDDGRRLLVTALTVIWGLRLAIH  85

Query  74   MYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKP  130
            + R+  G GEDPRYA +L    G   + ALRKV+ LQG L   VS P+Q +        P
Sbjct  86   IGRRGKGHGEDPRYAKMLAKAPGNPQLYALRKVYLLQGALVWLVSLPVQAAQYL---TAP  142

Query  131  LLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVW  190
            L      G+ +W VG+ FEA+GD QL  FK+DPAN+G +MDRGLW+WTRHPNYFGD CVW
Sbjct  143  LAWWAWAGVLLWAVGLAFEAIGDAQLARFKADPANKGKVMDRGLWSWTRHPNYFGDFCVW  202

Query  191  WGLWLITIN-DWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPR  249
            WGL+L       A  ATV +PL+M++LL   SGA L ER++  RPGFAEY+ RT+ F PR
Sbjct  203  WGLFLFVCQAPAAAAATVVAPLVMSFLLTKGSGAALLERHMADRPGFAEYRARTSGFFPR  262

Query  250  PPRSA  254
            PPR A
Sbjct  263  PPRRA  267


>gi|119718758|ref|YP_925723.1| hypothetical protein Noca_4539 [Nocardioides sp. JS614]
 gi|119539419|gb|ABL84036.1| protein of unknown function DUF1295 [Nocardioides sp. JS614]
Length=260

 Score =  212 bits (540),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 130/254 (52%), Positives = 164/254 (65%), Gaps = 14/254 (5%)

Query  7    ALAVAV-VHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVST  65
            +LAVAV V +V      R GR +VVDV WG+  VAVA+  A L      + WLLL LV+ 
Sbjct  11   SLAVAVLVMTVTALAAARAGRVSVVDVAWGIALVAVALVCAVLA--GTWQSWLLLVLVAV  68

Query  66   WGLRLSWHMYRKTAGQGEDPRYADLLRGATPV----QALRKVFGLQGLLTLFVSFPLQLS  121
            WG RLS H++  + G GEDPRY  LL G        +A+RKVF +QG     VS PLQ +
Sbjct  69   WGGRLSAHIFTTSRGHGEDPRYEALLGGTLDRVGMGRAVRKVFLVQGAAVWLVSLPLQAA  128

Query  122  AVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHP  181
            A+ G      +    VG+AVWLVG+ FEAVGD QL  ++ DP +RG ++DRGLW+WTRHP
Sbjct  129  ALAGVDWTGAI---WVGVAVWLVGVLFEAVGDAQLGAYRRDP-DRGPVLDRGLWSWTRHP  184

Query  182  NYFGDACVWWGLWLI--TINDW-APLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAE  238
            NYFGDACVWWG+WL     + W A LA+V SP+ MT  LV ++GARL ER +  RPG+ E
Sbjct  185  NYFGDACVWWGIWLAGGVASGWVAGLASVLSPVAMTIWLVWITGARLLERTMMQRPGYPE  244

Query  239  YQRRTAYFVPRPPR  252
            Y  RT+ FVP PP+
Sbjct  245  YAARTSMFVPLPPK  258


>gi|344998663|ref|YP_004801517.1| hypothetical protein SACTE_1051 [Streptomyces sp. SirexAA-E]
 gi|344314289|gb|AEN08977.1| protein of unknown function DUF1295 [Streptomyces sp. SirexAA-E]
Length=268

 Score =  207 bits (526),  Expect = 2e-51, Method: Compositional matrix adjust.
 Identities = 131/248 (53%), Positives = 160/248 (65%), Gaps = 15/248 (6%)

Query  13   VHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLRL  70
            V  V F I  R+G + VVDV WGLGF AVA+ +  L  G GD  RR L+  L   WG RL
Sbjct  23   VMLVTFLIALRMGVHRVVDVAWGLGFAAVALVSYALSWGDGDGARRVLVTVLTVVWGGRL  82

Query  71   SWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLS-AVTGP  126
            + H+ R+  G GEDPRYAD+L    G   + ALRKV+ LQG L   VS P+Q +  +TGP
Sbjct  83   AVHIGRRGRGHGEDPRYADMLAKAPGDPDLYALRKVYLLQGGLVWLVSLPVQAAYHLTGP  142

Query  127  TPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGD  186
                  A    G  +W VG+ FEAVGD QL  F+ DPAN+G IMDRGLWAWTRHPNYFGD
Sbjct  143  MGWWAWA----GTVLWAVGLGFEAVGDAQLARFRRDPANKGRIMDRGLWAWTRHPNYFGD  198

Query  187  ACVWWGLWLITINDWAPL---ATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRT  243
             CVWWGL+LI      P+   AT+ SP++M+ LL   SG  L ER+++GRPGFAEY+ RT
Sbjct  199  FCVWWGLFLIVCQ--VPVVAAATLVSPVVMSLLLTKGSGKALLERHMEGRPGFAEYRART  256

Query  244  AYFVPRPP  251
            + F P PP
Sbjct  257  SGFFPLPP  264


>gi|167966530|ref|ZP_02548807.1| hypothetical protein MtubH3_00067 [Mycobacterium tuberculosis 
H37Ra]
Length=100

 Score =  202 bits (515),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 97/98 (99%), Positives = 97/98 (99%), Gaps = 0/98 (0%)

Query  159  FKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLV  218
             KSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLV
Sbjct  3    IKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLV  62

Query  219  DVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR  256
            DVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR
Sbjct  63   DVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR  100


>gi|256393408|ref|YP_003114972.1| hypothetical protein Caci_4267 [Catenulispora acidiphila DSM 
44928]
 gi|256359634|gb|ACU73131.1| protein of unknown function DUF1295 [Catenulispora acidiphila 
DSM 44928]
Length=275

 Score =  199 bits (505),  Expect = 4e-49, Method: Compositional matrix adjust.
 Identities = 119/244 (49%), Positives = 148/244 (61%), Gaps = 6/244 (2%)

Query  15   SVAFAIGRRIGRYNVVDVVWGLGFV--AVAVAAATLGHGDPVRRWLLLALVSTWGLRLSW  72
            S  F  G    R+  VD VWG  F   AV  AA T  HGD  RRWLL      WGLRLS 
Sbjct  25   SAVFVAGVARQRHRYVDAVWGSAFALAAVVTAAMTTEHGDGWRRWLLTLCTIVWGLRLSI  84

Query  73   HMYRKTAGQGEDPRYADLL---RGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPK  129
            H+ R+  G  EDPRYA +L   RG   + A  KV+ LQ +L  F+S P+Q+  V      
Sbjct  85   HIARRGWGAPEDPRYAAMLGKARGNPTLVAYTKVYLLQAVLVWFISLPVQVGLVATGGSA  144

Query  130  PLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACV  189
              +    +GL +WL+GI+FEA GD+QL  FK+DPAN G +M  GLW +TRHPNYFGDACV
Sbjct  145  WGVTPAVIGLLLWLLGISFEATGDYQLARFKADPANHGRLMSEGLWRYTRHPNYFGDACV  204

Query  190  WWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKG-RPGFAEYQRRTAYFVP  248
            WWGL+LI    W    T+ SP LMT+LL   SG  + E +L   RPG+A+Y  RT+ F+P
Sbjct  205  WWGLFLIGAAAWPVPLTILSPALMTWLLTSGSGKPMVEAHLTNTRPGYADYVARTSGFIP  264

Query  249  RPPR  252
            RPP+
Sbjct  265  RPPK  268


>gi|116669894|ref|YP_830827.1| hypothetical protein Arth_1333 [Arthrobacter sp. FB24]
 gi|116610003|gb|ABK02727.1| protein of unknown function DUF1295 [Arthrobacter sp. FB24]
Length=270

 Score =  196 bits (499),  Expect = 2e-48, Method: Compositional matrix adjust.
 Identities = 119/252 (48%), Positives = 155/252 (62%), Gaps = 8/252 (3%)

Query  6    SALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALV  63
            +ALAVA V +V FA+     R++V+DV WG GFVAVA  +  L  G GD  RR LLL L 
Sbjct  16   TALAVASVLAVTFAVAVAQRRHSVMDVAWGPGFVAVAAVSWLLSAGTGDDGRRLLLLLLT  75

Query  64   STWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQL  120
              WGLRL  H+  +  G  EDPRY  +L    G+  V ALR+V+  QG++ LFVS  +Q+
Sbjct  76   GVWGLRLGAHIGWRARGGHEDPRYEAMLSDAPGSRNVYALRRVYLPQGMVMLFVSLTVQV  135

Query  121  SAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRH  180
                   P     V  +G+ +W+VG  FE VGDWQL  FK DP+ +G +++ GLW +TRH
Sbjct  136  GMFATGAPG---WVAILGVVLWVVGFVFETVGDWQLTQFKKDPSRKGTVLNTGLWRYTRH  192

Query  181  PNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQ  240
            PNYFGDA VW GL+LI  + W  + TV SP LM + L   +G  LTE+ +  RPG+ EY 
Sbjct  193  PNYFGDAAVWTGLFLIAADSWPGILTVLSPALMVWALAGKTGKPLTEKAMSARPGYKEYV  252

Query  241  RRTAYFVPRPPR  252
              T+ FVP PPR
Sbjct  253  ESTSGFVPWPPR  264


>gi|331698463|ref|YP_004334702.1| hypothetical protein Psed_4702 [Pseudonocardia dioxanivorans 
CB1190]
 gi|326953152|gb|AEA26849.1| protein of unknown function DUF1295 [Pseudonocardia dioxanivorans 
CB1190]
Length=277

 Score =  196 bits (497),  Expect = 4e-48, Method: Compositional matrix adjust.
 Identities = 107/240 (45%), Positives = 146/240 (61%), Gaps = 6/240 (2%)

Query  23   RIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLRLSWHMYRKTAG  80
            R GR++ +DVVWG GF  VA+    +  G G+  RRWL  AL   WGLRL+WH+ R+  G
Sbjct  37   RGGRHDGIDVVWGAGFAVVALVTLVMSAGDGETWRRWLTTALTVVWGLRLAWHIGRRNHG  96

Query  81   QGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGV  137
            + ED RY  L+    G   V A  +++  QG++   VS P+QL+               +
Sbjct  97   KPEDQRYVALMSRAPGNPYVYAFTRIYLTQGVVMWVVSLPVQLAQYGTGGGLLGTVTAVL  156

Query  138  GLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLIT  197
            G+  W VG  FE VGD QL  F +DP N+G ++DRGLW +TRHPNYFGDA VWWGL L+ 
Sbjct  157  GVLSWCVGFFFETVGDAQLARFTADPGNKGTVLDRGLWRYTRHPNYFGDAAVWWGLTLLG  216

Query  198  INDWAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRRTAYFVPRPPRSARR  256
            ++    L  + S  +MT+LLV  +GA+L E  + + RPG+A+Y RRT+ F+PRPPR   R
Sbjct  217  LHQLPGLVGLASAAIMTFLLVRGTGAKLLESSIGERRPGYADYVRRTSGFIPRPPREPAR  276


>gi|258655282|ref|YP_003204438.1| hypothetical protein Namu_5181 [Nakamurella multipartita DSM 
44233]
 gi|258558507|gb|ACV81449.1| protein of unknown function DUF1295 [Nakamurella multipartita 
DSM 44233]
Length=293

 Score =  191 bits (486),  Expect = 7e-47, Method: Compositional matrix adjust.
 Identities = 117/245 (48%), Positives = 152/245 (63%), Gaps = 16/245 (6%)

Query  17   AFAIGRRIGRYNVVDVVWGLGFVAVA---------VAAATLGH--GDPVRRWLLLALVST  65
            +F  GR  G+Y+V+D  WG GF A+A         VA ++ G   GD   R L+L +V  
Sbjct  22   SFLAGRVTGKYSVIDAAWGPGFAAIALVTFVVSGLVAGSSAGQSPGDGTLRLLVLGMVVV  81

Query  66   WGLRLSWHMYRKTAGQGEDPRYADLLRGAT-PVQALRKVFGLQGLLTLFVSFPLQLSAVT  124
            WGLRL  ++  +  G+ EDPRYA++L  A  P   +RKV   QG+   FVS P+Q++ V 
Sbjct  82   WGLRLGTYILIRNHGKPEDPRYAEMLADAGGPGVIVRKVQLPQGVTMWFVSLPVQVAMVL  141

Query  125  GPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYF  184
               P P   +  VGLAV+LVG+ FE VGD QL  F  DPAN+G +MDRGLW +TRHPNYF
Sbjct  142  ---PGPAGPIIWVGLAVYLVGLVFETVGDAQLAAFTRDPANKGKLMDRGLWRYTRHPNYF  198

Query  185  GDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRRT  243
            GDACVW G++L     W    TV SP LM +LLV  +G  LTER + + RPG+A+Y  RT
Sbjct  199  GDACVWVGIFLTVTWSWWGWLTVLSPALMIWLLVAKTGKALTERRMSQSRPGYADYVART  258

Query  244  AYFVP  248
            + FVP
Sbjct  259  SGFVP  263


>gi|154253342|ref|YP_001414166.1| hypothetical protein Plav_2902 [Parvibaculum lavamentivorans 
DS-1]
 gi|154157292|gb|ABS64509.1| protein of unknown function DUF1295 [Parvibaculum lavamentivorans 
DS-1]
Length=264

 Score =  188 bits (477),  Expect = 7e-46, Method: Compositional matrix adjust.
 Identities = 111/229 (49%), Positives = 141/229 (62%), Gaps = 6/229 (2%)

Query  29   VVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMY-RKTAGQGEDPRY  87
            +VD+ WGLGFV +A+A  +L  G   R  L+  L + WGLRL+ H+Y R      ED RY
Sbjct  34   IVDIFWGLGFVIIALATWSLNPGYSTRAALIAGLTALWGLRLAGHLYLRWRREASEDRRY  93

Query  88   ADLLRGATPV---QALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLV  144
            A +     P    ++L  VFGLQ  +   VS P+Q   +   TP  L     +G  + L 
Sbjct  94   AAMRAKRGPSFWWKSLYIVFGLQAAIMFAVSLPVQF-GIMAETPGRLTLADVLGTVLVLT  152

Query  145  GITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPL  204
            G+ FEA+GD QL  FK+DPANRG +MDRGLWAWTRHPNYFGDA VWWGL++I  +  A  
Sbjct  153  GLAFEAIGDAQLTAFKADPANRGKVMDRGLWAWTRHPNYFGDAVVWWGLFIIAASSPALW  212

Query  205  ATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRRTAYFVPRPPR  252
             T   P LMT+ LV+VSG  L ER L K RPG+ +Y  RT+ F+P PPR
Sbjct  213  WTAIGPALMTWFLVNVSGKALLERGLRKSRPGYDDYVWRTSGFIPLPPR  261


>gi|300784853|ref|YP_003765144.1| hypothetical protein AMED_2949 [Amycolatopsis mediterranei U32]
 gi|299794367|gb|ADJ44742.1| conserved hypothetical protein [Amycolatopsis mediterranei U32]
 gi|340526282|gb|AEK41487.1| hypothetical protein RAM_14995 [Amycolatopsis mediterranei S699]
Length=255

 Score =  187 bits (476),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 103/237 (44%), Positives = 147/237 (63%), Gaps = 7/237 (2%)

Query  18   FAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRK  77
            F I R   RY+ +D  WGLGF  VA+AA   G G    R +++ L   WG+RLS H++ +
Sbjct  21   FGIARARKRYDTIDTFWGLGFAIVALAAFPFGDGPLPLRLVVVLLTVVWGVRLSVHLHLR  80

Query  78   TAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGV  137
                 EDPRYA +  G  P++   +V+  Q ++  FVS P+Q  AV G     +  +G +
Sbjct  81   NHKLPEDPRYARM--GHRPLKMFLRVYLFQAVVLYFVSLPVQF-AVDGTG---IGVLGWL  134

Query  138  GLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLIT  197
            G+AVW+VG  FE +GD QL  FK+DPA++G ++D GLW +TRHPNYFGDACVWWGL+L+ 
Sbjct  135  GVAVWVVGFAFETIGDDQLRRFKADPASKGKVLDTGLWRYTRHPNYFGDACVWWGLYLLA  194

Query  198  INDWAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRRTAYFVPRPPRS  253
             + W   AT+ SP+ MT+ L   +G  + E+ + + RP +A Y  RT+ F P PP+ 
Sbjct  195  CSTWPGAATILSPVAMTFTLARGTGKPMLEKGMARTRPAYAHYVERTSGFFPLPPKK  251


>gi|254387382|ref|ZP_05002630.1| conserved hypothetical protein [Streptomyces sp. Mg1]
 gi|194346175|gb|EDX27141.1| conserved hypothetical protein [Streptomyces sp. Mg1]
Length=266

 Score =  187 bits (475),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 112/244 (46%), Positives = 152/244 (63%), Gaps = 9/244 (3%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATL--GHGDPVRRWLLLALVSTWGLRLSWH  73
            + F++    G + + D+  GL F AVA A   L  G+G+  RR L+ A    WG+RL+ H
Sbjct  18   ITFSVALIRGLHRLADIARGLAFAAVAAATYGLSEGYGNDGRRLLVAAATLLWGVRLAAH  77

Query  74   MYRKTAGQGEDPRYADLL---RGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKP  130
            +  +  GQGEDPRYA+LL   RG   ++ALRKV  L+  L   VS P+Q ++       P
Sbjct  78   IAWRCRGQGEDPRYAELLAHGRGDPDLRALRKVHLLRAGLVWLVSLPVQAASYVA---AP  134

Query  131  LLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVW  190
            + A+  +G  +W  G+ FEAVGD QL  FK+DPA+ G +MDRGLWAWTRHPN+FGD  VW
Sbjct  135  IGALTVLGAVLWAAGLAFEAVGDHQLARFKADPAHHGTVMDRGLWAWTRHPNHFGDFLVW  194

Query  191  WGLWLITINDW-APLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPR  249
            WGL+L+    W   L ++ SP+ MT LL + SG RL   ++  RPG+A Y  RT+ F+PR
Sbjct  195  WGLYLMACGTWQTALLSLVSPVAMTLLLTEGSGKRLLVAHMADRPGYAAYAARTSGFIPR  254

Query  250  PPRS  253
            PPR 
Sbjct  255  PPRD  258


>gi|302528461|ref|ZP_07280803.1| conserved hypothetical protein [Streptomyces sp. AA4]
 gi|302437356|gb|EFL09172.1| conserved hypothetical protein [Streptomyces sp. AA4]
Length=265

 Score =  185 bits (470),  Expect = 5e-45, Method: Compositional matrix adjust.
 Identities = 107/257 (42%), Positives = 152/257 (60%), Gaps = 12/257 (4%)

Query  1    VVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLL  60
            +   V+ LAV    ++ F I R   RY+ +D  WGLGF  VAV +   G G    R    
Sbjct  13   LTAGVTLLAV----TLTFGIARLRRRYDTIDTFWGLGFALVAVVSFPFGTGPLALRLTTA  68

Query  61   ALVSTWGLRLSWHMYRKTAGQGEDPRYADLLR--GATP-VQALRKVFGLQGLLTLFVSFP  117
            AL   WG+RL+ H++ +  G+ EDPRY  ++   GA P  +   + + +Q  +  FVS P
Sbjct  69   ALTVVWGVRLAVHLHLRNRGKPEDPRYQQIVERAGANPGFRIFVRTYLMQAAVLWFVSLP  128

Query  118  LQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAW  177
            +Q  A++G   K       +G+  WLVG  FE VGD QL  F+++PANRG ++D GLW +
Sbjct  129  VQF-AMSG---KGFGLTAWLGVLGWLVGFAFETVGDEQLRRFRANPANRGQVLDTGLWRY  184

Query  178  TRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKG-RPGF  236
            TRHPNYFGDACVWWGL+L+  + W   AT+ SP+ MT+ L   +G  + E+ L+  RPG+
Sbjct  185  TRHPNYFGDACVWWGLYLLACSTWPGAATILSPVAMTFTLARGTGKPMLEKGLRQTRPGY  244

Query  237  AEYQRRTAYFVPRPPRS  253
            A+Y  RT+ F P PP+ 
Sbjct  245  ADYIARTSGFFPLPPKK  261


>gi|254421083|ref|ZP_05034807.1| conserved hypothetical protein [Brevundimonas sp. BAL3]
 gi|196187260|gb|EDX82236.1| conserved hypothetical protein [Brevundimonas sp. BAL3]
Length=270

 Score =  184 bits (467),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 106/259 (41%), Positives = 150/259 (58%), Gaps = 13/259 (5%)

Query  7    ALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTW  66
            AL VAV+  + + +  ++   + +D VW LG + +A+A      GDP R+ LL+ L + W
Sbjct  15   ALIVAVMLGL-WLVALKLKDVSFIDAVWPLGMLLLALATLPRAEGDPARKGLLVGLCAVW  73

Query  67   GLRLSWHMYRKTAGQGEDPRYADLLRGATPVQ-------ALRKVFGLQGLLTLFVSFPLQ  119
             LRL WH++R+    G D RY  ++              AL  VF  Q +L    S P+Q
Sbjct  74   ALRLGWHLFRRWRASGADGRYVQIVEDQEKSHGWSFGKTALLFVFLPQAVLAWLTSLPVQ  133

Query  120  LSAVTGPTPKPLLAV-GGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWT  178
            +  V     +P L V  G+G  + +VGI FE+VGD QL  FK DPAN+G ++D GLW +T
Sbjct  134  MGQVAA---QPGLGVMAGLGAVLAVVGIVFESVGDAQLAAFKRDPANKGKVLDTGLWRYT  190

Query  179  RHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFA  237
            RHPNYFGDACVWWGLWLI       L ++  P+ +T+ L   SG  +TE+ + + RPG+A
Sbjct  191  RHPNYFGDACVWWGLWLIAAETGVGLWSIAGPIFLTFTLTRWSGIGITEKAINRSRPGYA  250

Query  238  EYQRRTAYFVPRPPRSARR  256
            +Y +RT+ FVP PP    R
Sbjct  251  DYVKRTSAFVPWPPSRHPR  269


>gi|302382141|ref|YP_003817964.1| hypothetical protein Bresu_1029 [Brevundimonas subvibrioides 
ATCC 15264]
 gi|302192769|gb|ADL00341.1| protein of unknown function DUF1295 [Brevundimonas subvibrioides 
ATCC 15264]
Length=268

 Score =  181 bits (458),  Expect = 1e-43, Method: Compositional matrix adjust.
 Identities = 100/240 (42%), Positives = 140/240 (59%), Gaps = 11/240 (4%)

Query  23   RIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQG  82
            R+   + +D VW LG + +A+       GDPVR+ LLL L + W +RL WH+  +  G G
Sbjct  30   RLKDVSFIDGVWPLGMLFLALITFPRTDGDPVRKGLLLWLCAVWAIRLGWHLLHRWRGHG  89

Query  83   EDPRYADLLRGATPVQ-------ALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVG  135
             D RY D++              AL  VF  Q  L      P+QL  V+ P P  + A+G
Sbjct  90   ADGRYTDIVEHQEKNHGWSFGKTALLFVFLPQAFLAWLTCLPVQLGQVS-PVPA-MGAIG  147

Query  136  GVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWL  195
             +G  + +VGI FE++GD QL  F+ DP N+G ++D GLW +TRHPNYFGDACVWWGLWL
Sbjct  148  WIGAVIVVVGIAFESIGDAQLSAFRKDPKNKGKVLDTGLWRYTRHPNYFGDACVWWGLWL  207

Query  196  ITIND-WAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRRTAYFVPRPPRS  253
            I     W  +A+V  P+ +T+ L   SG  +TE+   K +P +A+Y RRT+ F+P PP+ 
Sbjct  208  IAAETGWIGIASVLGPVFLTFTLTKWSGIGITEKSTAKTKPQYADYIRRTSAFIPMPPKK  267


>gi|87198584|ref|YP_495841.1| hypothetical protein Saro_0560 [Novosphingobium aromaticivorans 
DSM 12444]
 gi|87134265|gb|ABD25007.1| protein of unknown function DUF1295 [Novosphingobium aromaticivorans 
DSM 12444]
Length=265

 Score =  178 bits (452),  Expect = 6e-43, Method: Compositional matrix adjust.
 Identities = 109/240 (46%), Positives = 143/240 (60%), Gaps = 9/240 (3%)

Query  23   RIGRYNVVDVVWGLGFVAVAVAAATLGHGDP-VRRWLLLALVSTWGLRLSWHMYRKTAGQ  81
            RI   + +D VWG G   +A+ +     G P VR  L+ A+ + W  RL+WH+Y +    
Sbjct  25   RIDDVSFIDAVWGGGMGVLALVSWLHVPGGPGVRAHLIAAMAAIWAARLAWHLYTRWRAN  84

Query  82   GEDPRYADLL-----RGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGG  136
            GEDPRYA +L     RG     AL+ VF  Q +L      P QL  +    P PL  +  
Sbjct  85   GEDPRYARILGKARARGQYGSAALKVVFAPQAVLLFLTCLPAQLGVLASTAPAPLGPLAV  144

Query  137  VGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLI  196
             G AVWLVGI FEAVGD QL  F +DPA++G ++D GLW +TRHPNYFGDACVWWG+WL 
Sbjct  145  AGAAVWLVGILFEAVGDEQLKRFLADPASKGKVLDTGLWRFTRHPNYFGDACVWWGIWLA  204

Query  197  TIND--WAPLATVGSPLLMTYLLVDVSGARLTERYL-KGRPGFAEYQRRTAYFVPRPPRS  253
              +   W  LA++  P+ +T+ L   SG  L ER + + RPG+AEY RRT+ FVP  P+S
Sbjct  205  AADAGLWVALASLVGPVFLTFTLTRWSGKPLLERGMAERRPGYAEYVRRTSGFVPWWPKS  264


>gi|318057381|ref|ZP_07976104.1| hypothetical protein SSA3_05541 [Streptomyces sp. SA3_actG]
 gi|318078177|ref|ZP_07985509.1| hypothetical protein SSA3_16015 [Streptomyces sp. SA3_actF]
Length=290

 Score =  178 bits (452),  Expect = 6e-43, Method: Compositional matrix adjust.
 Identities = 118/265 (45%), Positives = 147/265 (56%), Gaps = 27/265 (10%)

Query  11   AVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAA-----------ATLGHGDPVRRWLL  59
            A+V    + + RR G Y  VD  WG  F  +A  +            + G GDPVR  L 
Sbjct  20   ALVLGATWLLSRRRGIYRYVDSAWGFAFAFLAAVSWLFAYGSQGTDGSRGLGDPVRAGLA  79

Query  60   LALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGA-----TPVQALRKVFGLQGLLTLFV  114
             AL   WGLRL  H+ R+  G+GEDPRY  +L  A      P  ALR V   Q  L   V
Sbjct  80   AALTIVWGLRLGVHIARRGRGKGEDPRYDRMLSKAPEGAPRPRYALRVVTLPQAALVWLV  139

Query  115  SFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGL  174
            S P+Q + +    P     V   G+A+W +G+ FEAVGD Q+  FKSDPA++G ++D GL
Sbjct  140  SVPVQAAVLL---PYGTWWVTWAGVALWALGLFFEAVGDAQMARFKSDPAHKGKLIDVGL  196

Query  175  WAWTRHPNYFGDACVWWGLWLITI--------NDWAPLATVGSPLLMTYLLVDVSGARLT  226
            W WTRHPNYFGD  VWWGLWL+T+              AT+ SPLLMTYLLV  SG RLT
Sbjct  197  WRWTRHPNYFGDFAVWWGLWLLTLPAAGAPAAAWGPAAATLVSPLLMTYLLVFGSGKRLT  256

Query  227  ERYLKGRPGFAEYQRRTAYFVPRPP  251
            ER +  R G+  Y  RT+ F+P PP
Sbjct  257  ERGMAEREGWERYAARTSGFLPWPP  281


>gi|325001851|ref|ZP_08122963.1| hypothetical protein PseP1_23956 [Pseudonocardia sp. P1]
Length=276

 Score =  177 bits (448),  Expect = 2e-42, Method: Compositional matrix adjust.
 Identities = 116/251 (47%), Positives = 154/251 (62%), Gaps = 10/251 (3%)

Query  5    VSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLG-----HGDPVRRWLL  59
            V+  AV V+  VA A+G R GR++ VDVVWGLGFV +A+ +A         GD  RR L+
Sbjct  15   VTLAAVLVLMVVALAVGVRRGRHDGVDVVWGLGFVLIALVSAVTATLLDPSGDAWRRVLV  74

Query  60   LALVSTWGLRLSWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSF  116
            + LV+ WG RL+ H+ R+  G+ ED RY DLL    G     A RKV+  QG +   VS 
Sbjct  75   VVLVTVWGGRLARHIARRNHGKPEDRRYVDLLARAPGNPAAYAFRKVYLTQGAVMWVVSL  134

Query  117  PLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWA  176
            P+Q+ A  G      + V  +G+ VW VG  FEAVGD QL  F +DPA+RG ++D GLW 
Sbjct  135  PVQI-APYGAVGTWGVVVTVLGMLVWAVGFGFEAVGDAQLARFTADPAHRGEVLDSGLWR  193

Query  177  WTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKG-RPG  235
            +TRHPNYFGDACVWWGL ++ +   A L  +    ++T  LV  +GA L ER +   RPG
Sbjct  194  YTRHPNYFGDACVWWGLGILALAHPAGLIGLVGVAVITANLVKGTGAALLERDIADRRPG  253

Query  236  FAEYQRRTAYF  246
            +A+Y RRT+ F
Sbjct  254  YADYVRRTSGF  264


>gi|291453039|ref|ZP_06592429.1| conserved hypothetical protein [Streptomyces albus J1074]
 gi|291355988|gb|EFE82890.1| conserved hypothetical protein [Streptomyces albus J1074]
Length=268

 Score =  176 bits (447),  Expect = 3e-42, Method: Compositional matrix adjust.
 Identities = 118/245 (49%), Positives = 150/245 (62%), Gaps = 12/245 (4%)

Query  16   VAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGH-----GDPVRRWLLLALVSTWGLRL  70
            V FA+  R G + +VDV WG  F AVA+ +          GD     L  AL   WGLRL
Sbjct  24   VTFALALRKGVHRIVDVAWGAAFAAVALTSYAFSRTRPDPGDTTLALLATALTCAWGLRL  83

Query  71   SWHMYRKTAGQGEDPRYADLLR---GATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPT  127
            + H+ R+  G GEDPRYA +L    G+    A RKV+ LQG L   VS P+Q +A+    
Sbjct  84   AVHIGRRGRGHGEDPRYARMLAKAPGSPAAYAFRKVYLLQGALVWLVSLPVQ-AAMYVRE  142

Query  128  PKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDA  187
            P  +LAV   G  +W VG+ FEA+GD QL  FK+DPAN+G IMDRGLW+WTRHPNYFGD 
Sbjct  143  PVGVLAV--CGAVLWAVGVAFEAIGDRQLARFKADPANKGKIMDRGLWSWTRHPNYFGDF  200

Query  188  CVWWGLWLI-TINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYF  246
             VWWGL+L+         AT+ SPL+M+ LL+  SG  L ER++  RPG+A Y+ RT+ F
Sbjct  201  LVWWGLFLLVCAAPPVAAATLVSPLVMSALLIFGSGKALLERHMAERPGYAAYRARTSGF  260

Query  247  VPRPP  251
             P PP
Sbjct  261  FPLPP  265



Lambda     K      H
   0.326    0.141    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 377837056800




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40