BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0472c Length=234 Score E Sequences producing significant alignments: (Bits) Value gi|254230820|ref|ZP_04924147.1| hypothetical protein TBCG_00464 ... 483 1e-134 gi|15607613|ref|NP_214986.1| TetR family transcriptional regulat... 480 6e-134 gi|15839861|ref|NP_334898.1| TetR family transcriptional regulat... 480 8e-134 gi|253797400|ref|YP_003030401.1| transcriptional regulator, tetR... 479 1e-133 gi|121636388|ref|YP_976611.1| TetR family transcriptional regula... 478 3e-133 gi|148821671|ref|YP_001286425.1| TetR family transcriptional reg... 477 5e-133 gi|308376405|ref|ZP_07438739.2| transcriptional regulator, tetR-... 464 6e-129 gi|183980821|ref|YP_001849112.1| TetR family transcriptional reg... 442 1e-122 gi|15828330|ref|NP_302593.1| TetR family transcriptional regulat... 435 3e-120 gi|240169855|ref|ZP_04748514.1| TetR family transcriptional regu... 432 1e-119 gi|118619635|ref|YP_907967.1| TetR family transcriptional regula... 431 6e-119 gi|296168074|ref|ZP_06850140.1| TetR family transcriptional regu... 422 2e-116 gi|41410063|ref|NP_962899.1| hypothetical protein MAP3965c [Myco... 412 2e-113 gi|108797620|ref|YP_637817.1| TetR family transcriptional regula... 411 4e-113 gi|254819800|ref|ZP_05224801.1| hypothetical protein MintA_07744... 411 4e-113 gi|118472997|ref|YP_885319.1| TetR family transcriptional regula... 407 7e-112 gi|342859026|ref|ZP_08715680.1| TetR family transcriptional regu... 402 3e-110 gi|118464651|ref|YP_883806.1| TetR family transcriptional regula... 401 4e-110 gi|333989100|ref|YP_004521714.1| TetR family transcriptional reg... 400 7e-110 gi|336460419|gb|EGO39317.1| transcriptional regulator [Mycobacte... 399 2e-109 gi|145220709|ref|YP_001131387.1| TetR family transcriptional reg... 393 1e-107 gi|120401820|ref|YP_951649.1| TetR family transcriptional regula... 392 2e-107 gi|289568391|ref|ZP_06448618.1| transcriptional regulator, tetR-... 389 2e-106 gi|169631164|ref|YP_001704813.1| TetR family transcriptional reg... 360 9e-98 gi|312141151|ref|YP_004008487.1| tetr family transcriptional reg... 269 2e-70 gi|229490189|ref|ZP_04384036.1| transcriptional regulator [Rhodo... 268 4e-70 gi|226305075|ref|YP_002765033.1| TetR family transcriptional reg... 268 6e-70 gi|226361240|ref|YP_002779018.1| TetR family transcriptional reg... 258 4e-67 gi|111019100|ref|YP_702072.1| transcriptional regulator [Rhodoco... 258 4e-67 gi|54027185|ref|YP_121427.1| putative transcriptional regulator ... 235 4e-60 gi|262200772|ref|YP_003271980.1| TetR family transcriptional reg... 213 2e-53 gi|326384046|ref|ZP_08205729.1| TetR family transcriptional regu... 207 9e-52 gi|343925750|ref|ZP_08765265.1| putative TetR family transcripti... 205 5e-51 gi|256374975|ref|YP_003098635.1| TetR family transcriptional reg... 140 1e-31 gi|134097661|ref|YP_001103322.1| TetR/AcrR family transcriptiona... 134 8e-30 gi|300783039|ref|YP_003763330.1| TetR family transcriptional reg... 132 5e-29 gi|302524389|ref|ZP_07276731.1| transcriptional regulator [Strep... 129 2e-28 gi|331694940|ref|YP_004331179.1| TetR family transcriptional reg... 125 5e-27 gi|257054735|ref|YP_003132567.1| transcriptional regulator [Sacc... 120 1e-25 gi|315506143|ref|YP_004085030.1| regulatory protein TetR [Microm... 117 2e-24 gi|302867447|ref|YP_003836084.1| regulatory protein TetR [Microm... 116 3e-24 gi|326331598|ref|ZP_08197888.1| transcriptional regulator, TetR ... 116 3e-24 gi|291300506|ref|YP_003511784.1| TetR family transcriptional reg... 114 1e-23 gi|317125017|ref|YP_004099129.1| TetR transcriptional regulator ... 111 8e-23 gi|284988923|ref|YP_003407477.1| TetR family transcriptional reg... 108 9e-22 gi|325000514|ref|ZP_08121626.1| TetR/AcrR family transcriptional... 104 1e-20 gi|152967972|ref|YP_001363756.1| TetR family transcriptional reg... 95.9 4e-18 gi|325003475|ref|ZP_08124587.1| TetR family transcriptional regu... 95.5 5e-18 gi|84496320|ref|ZP_00995174.1| putative TetR-family transcriptio... 92.8 4e-17 gi|296164135|ref|ZP_06846751.1| transcriptional regulatory prote... 92.0 6e-17 >gi|254230820|ref|ZP_04924147.1| hypothetical protein TBCG_00464 [Mycobacterium tuberculosis C] gi|124599879|gb|EAY58889.1| hypothetical protein TBCG_00464 [Mycobacterium tuberculosis C] Length=256 Score = 483 bits (1242), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 234/234 (100%), Positives = 234/234 (100%), Gaps = 0/234 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 23 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 82 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 83 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 142 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH Sbjct 143 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 202 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 203 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 256 >gi|15607613|ref|NP_214986.1| TetR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|31791652|ref|NP_854145.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97] gi|148660239|ref|YP_001281762.1| TetR family transcriptional regulator [Mycobacterium tuberculosis H37Ra] 54 more sequence titles Length=234 Score = 480 bits (1236), Expect = 6e-134, Method: Compositional matrix adjust. Identities = 233/234 (99%), Positives = 234/234 (100%), Gaps = 0/234 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +AERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 1 MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH Sbjct 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 >gi|15839861|ref|NP_334898.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|13879996|gb|AAK44712.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis CDC1551] Length=256 Score = 480 bits (1235), Expect = 8e-134, Method: Compositional matrix adjust. Identities = 233/234 (99%), Positives = 233/234 (99%), Gaps = 0/234 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 23 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 82 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNM AALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 83 LYRYFVDKNDLTTAVMMRFTQTTLIPNMXAALSADMDGFELTREIIRVYVETVAAQPEPY 142 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH Sbjct 143 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 202 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 203 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 256 >gi|253797400|ref|YP_003030401.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis KZN 1435] gi|253318903|gb|ACT23506.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis KZN 1435] Length=256 Score = 479 bits (1233), Expect = 1e-133, Method: Compositional matrix adjust. Identities = 233/234 (99%), Positives = 233/234 (99%), Gaps = 0/234 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 VA RIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 23 VAGRIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 82 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 83 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 142 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH Sbjct 143 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 202 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 203 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 256 >gi|121636388|ref|YP_976611.1| TetR family transcriptional regulator [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988860|ref|YP_002643547.1| putative transcriptional regulatory protein [Mycobacterium bovis BCG str. Tokyo 172] gi|121492035|emb|CAL70498.1| Probable transcriptional regulatory protein (possibly tetR-family) [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224771973|dbj|BAH24779.1| putative transcriptional regulatory protein [Mycobacterium bovis BCG str. Tokyo 172] gi|341600404|emb|CCC63074.1| probable transcriptional regulatory protein (possibly tetR-family) [Mycobacterium bovis BCG str. Moreau RDJ] Length=234 Score = 478 bits (1230), Expect = 3e-133, Method: Compositional matrix adjust. Identities = 232/234 (99%), Positives = 233/234 (99%), Gaps = 0/234 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +AERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 1 MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDT GVEPWAYLIVGGVQLATH Sbjct 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTDGVEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 >gi|148821671|ref|YP_001286425.1| TetR family transcriptional regulator [Mycobacterium tuberculosis F11] gi|254549420|ref|ZP_05139867.1| transcriptional regulator, tetR-family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|289552723|ref|ZP_06441933.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis KZN 605] 9 more sequence titles Length=234 Score = 477 bits (1228), Expect = 5e-133, Method: Compositional matrix adjust. Identities = 232/234 (99%), Positives = 233/234 (99%), Gaps = 0/234 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +A RIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 1 MAGRIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH Sbjct 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 >gi|308376405|ref|ZP_07438739.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis SUMu008] gi|308351221|gb|EFP40072.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis SUMu008] Length=225 Score = 464 bits (1193), Expect = 6e-129, Method: Compositional matrix adjust. Identities = 224/225 (99%), Positives = 225/225 (100%), Gaps = 0/225 (0%) Query 10 VKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKN 69 +KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKN Sbjct 1 MKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKN 60 Query 70 DLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSA 129 DLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSA Sbjct 61 DLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSA 120 Query 130 SKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS 189 SKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS Sbjct 121 SKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS 180 Query 190 SDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 234 SDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV Sbjct 181 SDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV 225 >gi|183980821|ref|YP_001849112.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183174147|gb|ACC39257.1| transcriptional regulatory protein (possibly TetR-family) [Mycobacterium marinum M] Length=234 Score = 442 bits (1138), Expect = 1e-122, Method: Compositional matrix adjust. Identities = 213/227 (94%), Positives = 221/227 (98%), Gaps = 0/227 (0%) Query 3 ERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLY 62 ERIPA+T KTDGRKRRWHQHKVERRNELVDGTI AIRRHGRFLSMDEIAAEIGVSKTVLY Sbjct 3 ERIPAMTGKTDGRKRRWHQHKVERRNELVDGTIVAIRRHGRFLSMDEIAAEIGVSKTVLY 62 Query 63 RYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRF 122 RYFVDKNDLTTAVMMRF QTTLIPNM AALS+++DGF+L REIIRVYVETVAA+PEPYRF Sbjct 63 RYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNLDGFDLAREIIRVYVETVAAEPEPYRF 122 Query 123 VMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSW 182 VMANSSASKSKVIADSERIIARMLAVMLRRRM EAGMDTGGVEPWAYLIVGGVQLATHSW Sbjct 123 VMANSSASKSKVIADSERIIARMLAVMLRRRMAEAGMDTGGVEPWAYLIVGGVQLATHSW 182 Query 183 MSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 MSDPRM+SDELIDYLTMLSWSALCGIVEAGGSLEKFR+QPHPSPIVP Sbjct 183 MSDPRMTSDELIDYLTMLSWSALCGIVEAGGSLEKFRDQPHPSPIVP 229 >gi|15828330|ref|NP_302593.1| TetR family transcriptional regulator [Mycobacterium leprae TN] gi|221230807|ref|YP_002504223.1| putative TetR-family transcriptional regulator [Mycobacterium leprae Br4923] gi|13094023|emb|CAC31974.1| possible TetR-family transcriptional regulator [Mycobacterium leprae] gi|219933914|emb|CAR72556.1| possible TetR-family transcriptional regulator [Mycobacterium leprae Br4923] Length=233 Score = 435 bits (1118), Expect = 3e-120, Method: Compositional matrix adjust. Identities = 206/232 (89%), Positives = 221/232 (96%), Gaps = 0/232 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +AE IPAV VKTDGRKRRWHQHKVERRNELVDGTI+AIRR GRFLSMDEIA +IGVSKTV Sbjct 1 MAEHIPAVAVKTDGRKRRWHQHKVERRNELVDGTIDAIRRQGRFLSMDEIAGKIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYF+DKNDLTTAVMMRF QTTLIPNM AALS ++DGF+LTREIIRVYV+TVAA+PEPY Sbjct 61 LYRYFIDKNDLTTAVMMRFAQTTLIPNMAAALSTNLDGFDLTREIIRVYVKTVAAEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 +FVMANSSASKSKVIADSERIIARMLAVM+RRRMQEAGMD GGVEPWAYLIVGGVQLATH Sbjct 121 QFVMANSSASKSKVIADSERIIARMLAVMIRRRMQEAGMDAGGVEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWG 232 SWMSDPRMS+DELIDYLTMLSW+ALCGIVE GGSLEKFR+QPHPSPI+P G Sbjct 181 SWMSDPRMSADELIDYLTMLSWNALCGIVEVGGSLEKFRKQPHPSPIIPPRG 232 >gi|240169855|ref|ZP_04748514.1| TetR family transcriptional regulator [Mycobacterium kansasii ATCC 12478] Length=235 Score = 432 bits (1112), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 208/229 (91%), Positives = 219/229 (96%), Gaps = 0/229 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 + E IPA T KTDGRKRRWHQHKVERRNELVDGTIEAIR GRFLSMDEIAAEIGVSKTV Sbjct 1 MTEHIPAPTGKTDGRKRRWHQHKVERRNELVDGTIEAIRVRGRFLSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRF QTTLIPNM AALS+++DG++LTRE+IRVYVETVA++PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNLDGYDLTREVIRVYVETVASEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARM+AVMLRRRMQE GMDTGGVEPWAYLIVGGVQLATH Sbjct 121 RFVMANSSASKSKVIADSERIIARMIAVMLRRRMQEVGMDTGGVEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 SWMS PRM+SDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP Sbjct 181 SWMSAPRMTSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 >gi|118619635|ref|YP_907967.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118571745|gb|ABL06496.1| transcriptional regulatory protein (possibly TetR-family) [Mycobacterium ulcerans Agy99] Length=227 Score = 431 bits (1107), Expect = 6e-119, Method: Compositional matrix adjust. Identities = 207/222 (94%), Positives = 216/222 (98%), Gaps = 0/222 (0%) Query 8 VTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVD 67 +T KTDGRKRRWHQHKVERRNELVDGTI AIRRHGRFLSMDEIAAEIGVSKTVLYRYFVD Sbjct 1 MTGKTDGRKRRWHQHKVERRNELVDGTIVAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVD 60 Query 68 KNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANS 127 KNDLTTAVMMRF QTTLIPNM AALS+++DGF+L REIIRVYVETVAA+PEPYRFVMANS Sbjct 61 KNDLTTAVMMRFAQTTLIPNMAAALSSNLDGFDLAREIIRVYVETVAAEPEPYRFVMANS 120 Query 128 SASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPR 187 SASKSKVIADSERIIARMLAVMLRRR+ EAGMDTGGVEPWAYLIVGGVQLATHSWMSDPR Sbjct 121 SASKSKVIADSERIIARMLAVMLRRRVAEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPR 180 Query 188 MSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 M+SDELIDYLTMLSWSALCGIVEAGGSLEKFR+QPHPSPIVP Sbjct 181 MTSDELIDYLTMLSWSALCGIVEAGGSLEKFRDQPHPSPIVP 222 >gi|296168074|ref|ZP_06850140.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896881|gb|EFG76509.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=239 Score = 422 bits (1084), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 202/232 (88%), Positives = 217/232 (94%), Gaps = 0/232 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +AER AV KTDGRKRRWHQHKVERRNELVDGTI+AIRRHG LSMDEIAAEIGVSKTV Sbjct 1 MAERTLAVAAKTDGRKRRWHQHKVERRNELVDGTIDAIRRHGGTLSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNM AAL++++DGF+LTRE+IRVYVETVA +PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMAAALTSNLDGFDLTREVIRVYVETVANEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVM+NSSASKSKVIADSERIIARMLAV++RRRMQ+AGMDTGG EPWAYLIVGGVQLATH Sbjct 121 RFVMSNSSASKSKVIADSERIIARMLAVLMRRRMQQAGMDTGGAEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWG 232 SWMS PRMS DELIDYLTMLSW+AL GIVE GGSLEKFRE+PHPSPIVP G Sbjct 181 SWMSSPRMSRDELIDYLTMLSWNALKGIVEVGGSLEKFREEPHPSPIVPPRG 232 >gi|41410063|ref|NP_962899.1| hypothetical protein MAP3965c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398896|gb|AAS06515.1| hypothetical protein MAP_3965c [Mycobacterium avium subsp. paratuberculosis K-10] Length=235 Score = 412 bits (1059), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 199/229 (87%), Positives = 215/229 (94%), Gaps = 0/229 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +AE+I A +VK DGRKRRWHQHKV+RRNELVDGTI+AIRR G LSMDEIAAEIGVSKTV Sbjct 1 MAEQITAASVKMDGRKRRWHQHKVDRRNELVDGTIDAIRRLGGALSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNM AAL++ +DGF+LTRE+IRVYVETVA +PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMAAALTSGLDGFDLTREVIRVYVETVANEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVM+NSSASKSKVIADSERIIARMLAV++RRRMQ AGMDTGGVEPWAYLIVGGVQLATH Sbjct 121 RFVMSNSSASKSKVIADSERIIARMLAVLMRRRMQHAGMDTGGVEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 SWMS PRMS DELIDYLTMLSW+AL GIVE GGSLEKFRE+PHPSPIVP Sbjct 181 SWMSYPRMSRDELIDYLTMLSWNALKGIVEVGGSLEKFREEPHPSPIVP 229 >gi|108797620|ref|YP_637817.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119866707|ref|YP_936659.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|126433244|ref|YP_001068935.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|108768039|gb|ABG06761.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119692796|gb|ABL89869.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] gi|126233044|gb|ABN96444.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=235 Score = 411 bits (1057), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 194/229 (85%), Positives = 213/229 (94%), Gaps = 0/229 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +A++ P + VKTDGRKRRWHQHKVERRNELVDGT+EAIRR G +SMDEIAAEIGVSKTV Sbjct 1 MAQQTPPLAVKTDGRKRRWHQHKVERRNELVDGTLEAIRRRGSNVSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRF QTTLIPNM AAL +++DG++LTREII+VYVETVA +PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALMSNLDGYDLTREIIKVYVETVANEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMAN+SASKSK +ADSERIIARMLAVMLRRRM +AGMDTGGVEPWAY IVGGVQLATH Sbjct 121 RFVMANNSASKSKAVADSERIIARMLAVMLRRRMAQAGMDTGGVEPWAYHIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 SWMS PRMS+DELIDYLTMLSWSALCGIVE GGSLEKFR +PHPSPI+P Sbjct 181 SWMSHPRMSADELIDYLTMLSWSALCGIVEVGGSLEKFRSEPHPSPILP 229 >gi|254819800|ref|ZP_05224801.1| hypothetical protein MintA_07744 [Mycobacterium intracellulare ATCC 13950] Length=239 Score = 411 bits (1056), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 198/229 (87%), Positives = 214/229 (94%), Gaps = 0/229 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 + E+I V VK DGRKRRWHQHKVERRNELVDGTI+AIRR G LSMDEIAAEIGVSKTV Sbjct 1 MTEQITVVRVKMDGRKRRWHQHKVERRNELVDGTIDAIRRLGGALSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNM AAL++++DGF+LTRE+IRVYVETVA +PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMAAALTSNLDGFDLTREVIRVYVETVANEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAV++RRRMQ+AGMDTGG EPWAYLIVGGVQLATH Sbjct 121 RFVMANSSASKSKVIADSERIIARMLAVLMRRRMQQAGMDTGGAEPWAYLIVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 SWMS PRM+ DELIDYLTMLSW+AL GIVE GGSLEKFRE+PHPSPIVP Sbjct 181 SWMSYPRMTRDELIDYLTMLSWNALKGIVEVGGSLEKFREEPHPSPIVP 229 >gi|118472997|ref|YP_885319.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118174284|gb|ABK75180.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=234 Score = 407 bits (1046), Expect = 7e-112, Method: Compositional matrix adjust. Identities = 194/229 (85%), Positives = 209/229 (92%), Gaps = 0/229 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +A++ P TVKTDGRKRRWHQHKVERRNELVDGT+EAIRR G +SMDEIAAEIGVSKTV Sbjct 1 MAQQTPPATVKTDGRKRRWHQHKVERRNELVDGTLEAIRRRGSNVSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRF QTTLIPNM AALS+++DGF LTREIIRVYVETVAA+PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNLDGFALTREIIRVYVETVAAEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMAN+SASKSK +ADSE+IIARMLAVMLRRRM E GMDTGGVE WA+ VGGVQLATH Sbjct 121 RFVMANNSASKSKAVADSEQIIARMLAVMLRRRMAEVGMDTGGVEAWAFHTVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 SWMS+PRM+SDELIDYLTMLSW ALCGIVE GGSLEKF QPHPSPI P Sbjct 181 SWMSNPRMTSDELIDYLTMLSWYALCGIVEVGGSLEKFNSQPHPSPIPP 229 >gi|342859026|ref|ZP_08715680.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342133267|gb|EGT86470.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=233 Score = 402 bits (1032), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 194/222 (88%), Positives = 208/222 (94%), Gaps = 0/222 (0%) Query 8 VTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVD 67 ++VK DGRKRRWHQHKVERRNELVDGTI+AIRR G LSMDEIAAEIGVSKTVLYRYFVD Sbjct 1 MSVKMDGRKRRWHQHKVERRNELVDGTIDAIRRLGGTLSMDEIAAEIGVSKTVLYRYFVD 60 Query 68 KNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANS 127 KNDLTTAVMMRFTQTTLIPNM AL++ +DGF+LTRE+IRVYVETVA +PEPYRFVM+NS Sbjct 61 KNDLTTAVMMRFTQTTLIPNMAGALTSGLDGFDLTREVIRVYVETVANEPEPYRFVMSNS 120 Query 128 SASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPR 187 SASKSKVIADSERIIARMLAV++RRRMQ AGMDTGGVEPWAYLIVGGVQLATHSWMS PR Sbjct 121 SASKSKVIADSERIIARMLAVLMRRRMQHAGMDTGGVEPWAYLIVGGVQLATHSWMSYPR 180 Query 188 MSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 MS DELIDYLTMLSW+AL GIVE GGSLEKFR +PHPSPIVP Sbjct 181 MSRDELIDYLTMLSWNALKGIVEVGGSLEKFRGEPHPSPIVP 222 >gi|118464651|ref|YP_883806.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254777115|ref|ZP_05218631.1| hypothetical protein MaviaA2_20949 [Mycobacterium avium subsp. avium ATCC 25291] gi|118165938|gb|ABK66835.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] Length=224 Score = 401 bits (1030), Expect = 4e-110, Method: Compositional matrix adjust. Identities = 193/217 (89%), Positives = 206/217 (95%), Gaps = 0/217 (0%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 DGRKRRWHQHKV+RRNELVDGTI+AIRR G LSMDEIAAEIGVSKTVLYRYFVDKNDLT Sbjct 2 DGRKRRWHQHKVDRRNELVDGTIDAIRRLGGALSMDEIAAEIGVSKTVLYRYFVDKNDLT 61 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKS 132 TAVMMRFTQTTLIPNM AAL++ +DGF+LTRE+IRVYVETVA +PEPYRFVM+NSSASKS Sbjct 62 TAVMMRFTQTTLIPNMAAALTSGLDGFDLTREVIRVYVETVANEPEPYRFVMSNSSASKS 121 Query 133 KVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDE 192 KVIADSERIIARMLAV++RRRMQ AGMDTGGVEPWAYLIVGGVQLATHSWMS PRMS DE Sbjct 122 KVIADSERIIARMLAVLMRRRMQHAGMDTGGVEPWAYLIVGGVQLATHSWMSYPRMSRDE 181 Query 193 LIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 LIDYLTMLSW+AL GIVE GGSLEKFRE+PHPSPIVP Sbjct 182 LIDYLTMLSWNALKGIVEVGGSLEKFREEPHPSPIVP 218 >gi|333989100|ref|YP_004521714.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333485068|gb|AEF34460.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] Length=237 Score = 400 bits (1028), Expect = 7e-110, Method: Compositional matrix adjust. Identities = 190/229 (83%), Positives = 210/229 (92%), Gaps = 0/229 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +AE+ A T KTDGRKRRWHQHKV+RRN+L+DGTIEAIRR GR++SMDEIAAEIGVSKTV Sbjct 1 MAEQPRAGTAKTDGRKRRWHQHKVDRRNDLIDGTIEAIRRRGRYVSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRF QTTLIPNM AALSA++DGF+L REIIRVYV+TVA +PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSANLDGFDLVREIIRVYVQTVANEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRM GM+T GVEPWAY+ VGGVQLATH Sbjct 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMTAVGMETSGVEPWAYMTVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 SW+ DPRMS+D+LIDYLTMLSW+ALCGIVE GGSLEKF PHPSP++P Sbjct 181 SWLLDPRMSADDLIDYLTMLSWNALCGIVEVGGSLEKFNAGPHPSPMLP 229 >gi|336460419|gb|EGO39317.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=224 Score = 399 bits (1025), Expect = 2e-109, Method: Compositional matrix adjust. Identities = 192/217 (89%), Positives = 205/217 (95%), Gaps = 0/217 (0%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 DGRKRRWHQHKV+RRNELVDGTI+AIRR G LSMDEIAAEIGVSKTVLYRYFVDKNDLT Sbjct 2 DGRKRRWHQHKVDRRNELVDGTIDAIRRLGGALSMDEIAAEIGVSKTVLYRYFVDKNDLT 61 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKS 132 TAVMMRFTQTTLIPNM AAL++ +DGF+LTRE+IRVYVETVA +PEPYRFVM+NSSASKS Sbjct 62 TAVMMRFTQTTLIPNMAAALTSGLDGFDLTREVIRVYVETVANEPEPYRFVMSNSSASKS 121 Query 133 KVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDE 192 KVIADSERIIARMLAV++ RRMQ AGMDTGGVEPWAYLIVGGVQLATHSWMS PRMS DE Sbjct 122 KVIADSERIIARMLAVLMHRRMQHAGMDTGGVEPWAYLIVGGVQLATHSWMSYPRMSRDE 181 Query 193 LIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 LIDYLTMLSW+AL GIVE GGSLEKFRE+PHPSPIVP Sbjct 182 LIDYLTMLSWNALKGIVEVGGSLEKFREEPHPSPIVP 218 >gi|145220709|ref|YP_001131387.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|315442339|ref|YP_004075218.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|145213195|gb|ABP42599.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] gi|315260642|gb|ADT97383.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=234 Score = 393 bits (1009), Expect = 1e-107, Method: Compositional matrix adjust. Identities = 183/230 (80%), Positives = 206/230 (90%), Gaps = 0/230 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 +A+ V VKTDGRKRRWHQHKVERRNELVDGT++AIRR G +SMDEIAAEIGVSKTV Sbjct 1 MAQHTSPVAVKTDGRKRRWHQHKVERRNELVDGTLDAIRRLGSNVSMDEIAAEIGVSKTV 60 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRF QTTLIPNM AAL++++DG+ELTRE+IRVYVETVA +PEPY Sbjct 61 LYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALTSNLDGYELTREVIRVYVETVANEPEPY 120 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 +FVMAN+SASKSK +ADSE IIARMLAVMLRRRM AGMD G EPWA+ VGGVQLATH Sbjct 121 QFVMANNSASKSKAVADSEAIIARMLAVMLRRRMAAAGMDASGAEPWAFHTVGGVQLATH 180 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPA 230 SWMS+PRM+SD+LIDYLTMLSWSALCGIVE GSLE FR+ PHPSP++P+ Sbjct 181 SWMSNPRMTSDDLIDYLTMLSWSALCGIVEVNGSLETFRQNPHPSPVLPS 230 >gi|120401820|ref|YP_951649.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954638|gb|ABM11643.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=227 Score = 392 bits (1007), Expect = 2e-107, Method: Compositional matrix adjust. Identities = 184/219 (85%), Positives = 203/219 (93%), Gaps = 0/219 (0%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 KTDGRKRRWH+HKVERRNELVDGT+EAIRR G +SMDEIAAEIGVSKTVLYRYFVDKND Sbjct 4 KTDGRKRRWHRHKVERRNELVDGTLEAIRRLGSNVSMDEIAAEIGVSKTVLYRYFVDKND 63 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSAS 130 LTTAVMMRF QTTLIPNM AALS+++DG++LTREII+VYVETVAA+PEPYRFVMAN+SAS Sbjct 64 LTTAVMMRFAQTTLIPNMAAALSSNLDGYDLTREIIKVYVETVAAEPEPYRFVMANNSAS 123 Query 131 KSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS 190 KSK +ADSE IIARMLAVMLRRRM AGMDTGG EPWAY IVGGVQLATHSWMS+PRM++ Sbjct 124 KSKAVADSETIIARMLAVMLRRRMVSAGMDTGGAEPWAYHIVGGVQLATHSWMSNPRMTA 183 Query 191 DELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVP 229 +ELIDYLTMLSWSALCGIVE GSL+ FR+ PHPSP +P Sbjct 184 EELIDYLTMLSWSALCGIVEVNGSLDTFRQSPHPSPALP 222 >gi|289568391|ref|ZP_06448618.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis T17] gi|289542144|gb|EFD45793.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis T17] Length=214 Score = 389 bits (1000), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 190/192 (99%), Positives = 191/192 (99%), Gaps = 0/192 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV Sbjct 23 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 82 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY Sbjct 83 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 142 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQL TH Sbjct 143 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLGTH 202 Query 181 SWMSDPRMSSDE 192 SWMSDPRMSSD+ Sbjct 203 SWMSDPRMSSDD 214 >gi|169631164|ref|YP_001704813.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169243131|emb|CAM64159.1| Possible TetR-family transcriptional regulator [Mycobacterium abscessus] Length=243 Score = 360 bits (924), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 173/223 (78%), Positives = 195/223 (88%), Gaps = 0/223 (0%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 VA + +KTDGRKRRWH+HKVERR ELVDGT++AIR GR +SMDEIA++IGVSKTV Sbjct 5 VASKTQPAAIKTDGRKRRWHKHKVERRTELVDGTLDAIRHRGRDISMDEIASDIGVSKTV 64 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYRYFVDKNDLTTAVM RF QTTLIP M AALSA +DG++LTR +I+VYVETVAA+PE Y Sbjct 65 LYRYFVDKNDLTTAVMTRFAQTTLIPKMAAALSARLDGYDLTRTVIKVYVETVAAEPEIY 124 Query 121 RFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 FVMANSSAS+SK IADSERIIARMLA+MLRRRM EAGMDT GVEPWAY+IVGGVQLATH Sbjct 125 PFVMANSSASRSKAIADSERIIARMLALMLRRRMHEAGMDTHGVEPWAYMIVGGVQLATH 184 Query 181 SWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPH 223 SWMS PRMSSDELIDYLTM++W+AL GIV+ GGS EKF + H Sbjct 185 SWMSHPRMSSDELIDYLTMIAWNALLGIVDVGGSREKFVDMVH 227 >gi|312141151|ref|YP_004008487.1| tetr family transcriptional regulator [Rhodococcus equi 103S] gi|325674027|ref|ZP_08153717.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] gi|311890490|emb|CBH49808.1| putative TetR family transcriptional regulator [Rhodococcus equi 103S] gi|325555292|gb|EGD24964.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] Length=253 Score = 269 bits (688), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 126/216 (59%), Positives = 159/216 (74%), Gaps = 0/216 (0%) Query 9 TVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDK 68 T K DGRKRRW +HK+ RR ELVDGTI AIR GR + MD+IA+EIGVSKTVLYRYF DK Sbjct 23 TGKPDGRKRRWREHKIARREELVDGTIAAIRARGRDIGMDDIASEIGVSKTVLYRYFTDK 82 Query 69 NDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSS 128 NDLT+A MMR+ +T L P M A + D+D ++LTR I YVETVAA P+ Y +VMANS+ Sbjct 83 NDLTSATMMRYVETILAPRMYAVIGEDLDEYDLTRVAISAYVETVAADPDVYLYVMANSA 142 Query 129 ASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRM 188 V+ADSER+IA +LA +L R++ GMD+GG PWAY +VG VQLATH W+S+ M Sbjct 143 GPNRDVVADSERMIAELLATVLGERLRNMGMDSGGSVPWAYGVVGAVQLATHWWISNKSM 202 Query 189 SSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHP 224 S+D+LIDYL M++W + GI + GS +F+ PHP Sbjct 203 STDDLIDYLVMMTWGGISGIAASSGSPARFKSVPHP 238 >gi|229490189|ref|ZP_04384036.1| transcriptional regulator [Rhodococcus erythropolis SK121] gi|229322937|gb|EEN88711.1| transcriptional regulator [Rhodococcus erythropolis SK121] Length=244 Score = 268 bits (685), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 125/214 (59%), Positives = 160/214 (75%), Gaps = 0/214 (0%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 K+DGRKRRW +HK+ RR ELVDGTI AIR GR + MDEIA+EIGVSKTVLYRYF DK+D Sbjct 24 KSDGRKRRWREHKIARREELVDGTIAAIRARGREIGMDEIASEIGVSKTVLYRYFADKSD 83 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSAS 130 LTTA MMR+ +T L P + A+S D+D FELT+ I YVETVA+ P+ Y +VMAN + + Sbjct 84 LTTATMMRYVETILSPRIYEAISGDLDDFELTQASITAYVETVASDPDIYLYVMANGAGA 143 Query 131 KSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS 190 V+ADSER+IA +L+ +L R++E MD+GG PWA+ IVGG+QLATH W+S+ MS+ Sbjct 144 NRDVVADSERMIAELLSTVLGNRLREMEMDSGGSLPWAFGIVGGIQLATHWWISNKSMSA 203 Query 191 DELIDYLTMLSWSALCGIVEAGGSLEKFREQPHP 224 + LIDYLTM++W + GI GS KF+ PHP Sbjct 204 ESLIDYLTMMTWGGITGIAAVNGSPAKFKSVPHP 237 >gi|226305075|ref|YP_002765033.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226184190|dbj|BAH32294.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=239 Score = 268 bits (684), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 125/214 (59%), Positives = 160/214 (75%), Gaps = 0/214 (0%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 K+DGRKRRW +HK+ RR ELVDGTI AIR GR + MDEIA+EIGVSKTVLYRYF DK+D Sbjct 19 KSDGRKRRWREHKIARREELVDGTIAAIRARGREIGMDEIASEIGVSKTVLYRYFADKSD 78 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSAS 130 LTTA MMR+ +T L P + A+S D+D FELT+ I YVETVA+ P+ Y +VMAN + + Sbjct 79 LTTATMMRYVETILSPRIYEAISGDLDDFELTQASITAYVETVASDPDIYLYVMANGAGA 138 Query 131 KSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS 190 V+ADSER+IA +L+ +L R++E MD+GG PWA+ IVGG+QLATH W+S+ MS+ Sbjct 139 NRDVVADSERMIAELLSTVLGNRLREMEMDSGGSLPWAFGIVGGIQLATHWWISNKSMSA 198 Query 191 DELIDYLTMLSWSALCGIVEAGGSLEKFREQPHP 224 + LIDYLTM++W + GI GS KF+ PHP Sbjct 199 ESLIDYLTMMTWGGITGIAAVNGSPAKFKSVPHP 232 >gi|226361240|ref|YP_002779018.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226239725|dbj|BAH50073.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=246 Score = 258 bits (660), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 122/214 (58%), Positives = 155/214 (73%), Gaps = 0/214 (0%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 K DGRKRRW +HK+ RR ELVDGTI AIR GR + MDEIA+EIGVSKTVLYRYF DK+D Sbjct 24 KPDGRKRRWREHKIARREELVDGTIAAIRLRGRDIGMDEIASEIGVSKTVLYRYFADKSD 83 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSAS 130 LT A M R+ +TTL P + A+ D+D FELTR I YVETVA+ P+ Y ++MAN S Sbjct 84 LTNATMARYVETTLAPRIYEAIGGDLDDFELTRATITAYVETVASDPDVYLYIMANGSGP 143 Query 131 KSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS 190 + +ADSER+IA +L+ +L R+++ MD+GG PWAY IVGGVQLATH W+S+ MS Sbjct 144 GRETVADSERMIAEVLSTVLGERLRQMEMDSGGAVPWAYGIVGGVQLATHWWISNRSMSV 203 Query 191 DELIDYLTMLSWSALCGIVEAGGSLEKFREQPHP 224 ++LI+YLTM++W + GI GS +F PHP Sbjct 204 EDLINYLTMMTWGGVTGIAAVNGSPARFNAIPHP 237 >gi|111019100|ref|YP_702072.1| transcriptional regulator [Rhodococcus jostii RHA1] gi|110818630|gb|ABG93914.1| transcriptional regulator [Rhodococcus jostii RHA1] Length=231 Score = 258 bits (660), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 122/214 (58%), Positives = 155/214 (73%), Gaps = 0/214 (0%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 K DGRKRRW +HK+ RR ELVDGTI AIR GR + MDEIA+EIGVSKTVLYRYF DK+D Sbjct 9 KPDGRKRRWREHKIARREELVDGTIAAIRLRGRDIGMDEIASEIGVSKTVLYRYFADKSD 68 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSAS 130 LT A M R+ +TTL P + A+ D+D FELTR I YVETVA+ P+ Y ++MAN S Sbjct 69 LTNATMARYVETTLAPRIYEAIGGDLDDFELTRATITAYVETVASDPDVYLYIMANGSGP 128 Query 131 KSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS 190 + +ADSER+IA +L+ +L R+++ MD+GG PWAY IVGGVQLATH W+S+ MS Sbjct 129 GRETVADSERMIAEVLSTVLGERLRQMEMDSGGAVPWAYGIVGGVQLATHWWISNRSMSV 188 Query 191 DELIDYLTMLSWSALCGIVEAGGSLEKFREQPHP 224 ++LI+YLTM++W + GI GS +F PHP Sbjct 189 EDLINYLTMMTWGGVTGIAAVNGSPARFNAIPHP 222 >gi|54027185|ref|YP_121427.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] gi|54018693|dbj|BAD60063.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] Length=226 Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 115/220 (53%), Positives = 152/220 (70%), Gaps = 4/220 (1%) Query 9 TVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDK 68 T + DGRKRRW QHK++RR ELVDGT+ A+R G MDEIAA+IGVSKTVLYRYF DK Sbjct 3 TGRVDGRKRRWRQHKIDRREELVDGTLAAVRTRGATAGMDEIAAQIGVSKTVLYRYFADK 62 Query 69 NDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSS 128 +DL A M RF +TTL+P + A+S D D F+LTR + YV TV PE YRF+M N S Sbjct 63 HDLVHATMQRFIETTLMPRVYGAISVDADEFQLTRSALAAYVVTVDEDPEVYRFIMGNGS 122 Query 129 ASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRM 188 + S +A+ E++ A +++ ++ R G+DT G + W+Y++VGG+QLATH W +D M Sbjct 123 DASS--LAEFEKLFADVVSAVIIDRAGSRGIDTKGSQLWSYVLVGGIQLATHWWTTDKSM 180 Query 189 SSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPH--PSP 226 +E+IDYLTM+ WSA+ G+ AGGS E F Q H P+P Sbjct 181 DREEVIDYLTMMVWSAIEGMARAGGSREIFNTQQHVLPTP 220 >gi|262200772|ref|YP_003271980.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262084119|gb|ACY20087.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=246 Score = 213 bits (543), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 107/222 (49%), Positives = 140/222 (64%), Gaps = 2/222 (0%) Query 6 PAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYF 65 P K DGR++RW +HK RR EL DG + A+R G + MDEIA IGVSKTVLYRYF Sbjct 19 PESGTKPDGRRQRWEKHKQNRRTELTDGVMNAVRELGADVGMDEIAGHIGVSKTVLYRYF 78 Query 66 VDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMA 125 DKNDL A +RF +TTL+P +I A+ D+D + LTR +I VYV VA +P Y F +A Sbjct 79 ADKNDLGVATTVRFFETTLLPRLIDAIHDDVDEYTLTRTVIGVYVHAVAGEPNLYSFALA 138 Query 126 NSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSD 185 SS + S A SE+++ ++L + RM E DT G W+ +VGG+Q WM+D Sbjct 139 -SSPTSSPAPAGSEKMVTQLLTATIVLRMTERSADTAGAAVWSNALVGGIQRVVDWWMAD 197 Query 186 PR-MSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSP 226 M++DELIDYLTM++WS++ GI GS EKF P P P Sbjct 198 QTVMAADELIDYLTMMAWSSIVGIAAVNGSREKFLAAPPPLP 239 >gi|326384046|ref|ZP_08205729.1| TetR family transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] gi|326197206|gb|EGD54397.1| TetR family transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] Length=242 Score = 207 bits (527), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 107/222 (49%), Positives = 141/222 (64%), Gaps = 2/222 (0%) Query 6 PAV-TVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRY 64 PAV V +DGRK+RW +HK++RR EL GT+EA+R G MD+IA IGVSKTVLYRY Sbjct 18 PAVEAVASDGRKQRWEKHKLDRRAELTAGTVEAVRVLGPDAGMDDIARHIGVSKTVLYRY 77 Query 65 FVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVM 124 F DKNDL AV + + ++T++P +I ALS D+ + L R +I VYVETV++ P YRF M Sbjct 78 FTDKNDLAAAVTLTYVESTIMPRLIEALSGDIGDYRLVRAVISVYVETVSSDPNVYRFTM 137 Query 125 ANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMS 184 A S S+ V A++E+I A L L R+ G TGG WA +VG + LA W++ Sbjct 138 ARPSGSR-PVAAEAEKIFAGALESTLEARLAARGAQTGGARTWARAMVGAITLAVEEWIA 196 Query 185 DPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSP 226 P +S ++ + LTML WS L GIV AGG E+F P P Sbjct 197 VPDRTSHDMAEELTMLVWSGLVGIVGAGGDPERFAADPPKFP 238 >gi|343925750|ref|ZP_08765265.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343764101|dbj|GAA12191.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=252 Score = 205 bits (521), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 102/214 (48%), Positives = 137/214 (65%), Gaps = 1/214 (0%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 K DGRK+RW +HK+ RR EL DG I A+R G + MDEIAA IGVSKTVLYRYF DK+D Sbjct 24 KPDGRKQRWEKHKLARRTELTDGVITAVRELGADVGMDEIAAHIGVSKTVLYRYFTDKSD 83 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSAS 130 L A +RF + T+ P + ALS D+D + LT II VYV V +P YRF +A SS + Sbjct 84 LGVATTVRFFENTIWPRLTEALSDDVDEYTLTHTIIGVYVHAVDDEPNLYRFALA-SSPT 142 Query 131 KSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS 190 S ADS R++++++ + RM E G DT G E W++ +VGG+Q WM+ + + Sbjct 143 SSPAPADSVRLVSQLVMSSIVMRMTERGADTTGAELWSHALVGGIQHVVDWWMTSRTLDA 202 Query 191 DELIDYLTMLSWSALCGIVEAGGSLEKFREQPHP 224 D+++DYLTM+ WSA+ G+ GS E F P P Sbjct 203 DQVVDYLTMMVWSAVVGVAAVDGSREAFLASPPP 236 >gi|256374975|ref|YP_003098635.1| TetR family transcriptional regulator [Actinosynnema mirum DSM 43827] gi|255919278|gb|ACU34789.1| transcriptional regulator, TetR family [Actinosynnema mirum DSM 43827] Length=275 Score = 140 bits (353), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 83/210 (40%), Positives = 115/210 (55%), Gaps = 6/210 (2%) Query 9 TVK--TDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFV 66 TVK TD R+ RW H+ RR E V+ TI A+ RHG + MDEIA E GVSK VLYR+F Sbjct 4 TVKGGTDARRERWKGHREARRAEFVEATIRAVARHGADVGMDEIAGEAGVSKPVLYRHFA 63 Query 67 DKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMAN 126 DK DL AV R T+ L+ + A+ D I+ Y+ + P YRFV+ Sbjct 64 DKADLYLAVGRRATE-LLMDRLGPAIEGDGSLRARITRIVDAYLSVIEEHPHLYRFVVRA 122 Query 127 SSASK---SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWM 183 + A + V+ + + +IA L + ++ GMD+GG EPWA+ +VG VQ A W+ Sbjct 123 AFAERPVEQDVVGEDKAMIATALTRLFGDFLRANGMDSGGAEPWAHALVGMVQNAGDWWL 182 Query 184 SDPRMSSDELIDYLTMLSWSALCGIVEAGG 213 MS L DYL+ + W AL G++ + G Sbjct 183 DRQSMSRASLGDYLSTIIWHALDGLLRSAG 212 >gi|134097661|ref|YP_001103322.1| TetR/AcrR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291006380|ref|ZP_06564353.1| TetR/AcrR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133910284|emb|CAM00397.1| transcriptional regulator (TetR/AcrR family) [Saccharopolyspora erythraea NRRL 2338] Length=255 Score = 134 bits (338), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 77/207 (38%), Positives = 116/207 (57%), Gaps = 6/207 (2%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 + D R+ RW +H+ RR E V+ + AIR HG + MDEIAA GVSK VLYR+F DK+D Sbjct 15 RGDARRERWREHRQARRAEFVEAAVRAIREHGADVGMDEIAATAGVSKPVLYRHFSDKSD 74 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVM----AN 126 L AV + L+ + AL E R II VY+ + P+ YRFV+ + Sbjct 75 LYVAV-GEWGAELLMNRLRPALGGQGSPNERIRRIIGVYLGVIEEFPDLYRFVVRRNFTD 133 Query 127 SSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDP 186 ++ V+A+ + +IA L+ +L M+ G+D+GGVE W++ +VG VQ + W+ Sbjct 134 RPVTQDPVVAE-KTVIANSLSRLLGEYMRALGLDSGGVEAWSHGLVGMVQASGDWWLDRQ 192 Query 187 RMSSDELIDYLTMLSWSALCGIVEAGG 213 MS + L DYL + W + G++ + G Sbjct 193 SMSRENLTDYLAQIIWYGIDGVLRSAG 219 >gi|300783039|ref|YP_003763330.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299792553|gb|ADJ42928.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340524418|gb|AEK39623.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=256 Score = 132 bits (331), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 73/204 (36%), Positives = 113/204 (56%), Gaps = 5/204 (2%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 D R+ RW +H++ RR E V+ + A+ HG L M+++AAE GV+K VLYR+F DK DL Sbjct 27 DARRDRWRKHRIARRKEFVEAALRALDTHGPDLGMEDVAAEAGVTKPVLYRHFDDKADLY 86 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASK- 131 A+ R T+ L +I A++A++ R + + + P YR +A+ K Sbjct 87 VALGQRGTE-ILFERLIPAINAELAPVPRIRMALDAFFTVIEEHPNLYRL-LAHGRPEKP 144 Query 132 --SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS 189 S V+A+ + +IA L +L M+ MD+G EPWA+ IVG VQ W+ MS Sbjct 145 VSSDVVAEDKELIATALTALLGDYMRMFNMDSGAAEPWAHGIVGMVQNTGEWWLDRRSMS 204 Query 190 SDELIDYLTMLSWSALCGIVEAGG 213 D +++YLT + W+A+ G+ G Sbjct 205 RDAVVEYLTQIIWAAIDGLTRQNG 228 >gi|302524389|ref|ZP_07276731.1| transcriptional regulator [Streptomyces sp. AA4] gi|302433284|gb|EFL05100.1| transcriptional regulator [Streptomyces sp. AA4] Length=261 Score = 129 bits (325), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 71/204 (35%), Positives = 110/204 (54%), Gaps = 4/204 (1%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 D R+ RW +H++ RR E V+ + A+ HG L M+++AAE GV+K VLYR+F DK DL Sbjct 28 DARRDRWRKHRIARRAEFVEAALRALDAHGPDLGMEDVAAEAGVTKPVLYRHFEDKADLY 87 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASK- 131 A+ R T+ L +I A++A++ R + + + P YR + K Sbjct 88 VALGQRGTE-ILFERLIPAINAELAPVPRIRMALDAFFGVIEEHPNLYRLLAHGGLPGKN 146 Query 132 --SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS 189 S V+A+ + +IA L +L M+ MD+G EPWA+ IVG VQ W+ M Sbjct 147 ADSDVVAEDKEVIATALTALLGDYMRMFNMDSGAAEPWAHGIVGMVQSTGEWWLDRRSMG 206 Query 190 SDELIDYLTMLSWSALCGIVEAGG 213 D +++YLT + W+A+ G+ G Sbjct 207 RDSVVEYLTQIIWAAIDGLTRQQG 230 >gi|331694940|ref|YP_004331179.1| TetR family transcriptional regulator [Pseudonocardia dioxanivorans CB1190] gi|326949629|gb|AEA23326.1| transcriptional regulator, TetR family [Pseudonocardia dioxanivorans CB1190] Length=273 Score = 125 bits (314), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 70/193 (37%), Positives = 113/193 (59%), Gaps = 4/193 (2%) Query 28 NELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPN 87 NE+V +EA+R HG +S+ EIAA G++K VLYRYF D+ DL AV L+ Sbjct 38 NEMVTAAVEAVRTHGAGVSVAEIAARAGITKPVLYRYFADRADLQRAVG-EHAVGMLMQR 96 Query 88 MIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMAN--SSASKSKVIADSERIIARM 145 M+ ALSA+++ E ++ ++ + +P+ +RFV+ N + ++++ D+ IARM Sbjct 97 MVPALSAELEPREQVAAVVDAFLAGIEEEPQLWRFVVHNPVEREAGTELVDDAREQIARM 156 Query 146 LAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDELIDYLTMLSWSAL 205 LA ++ R++ AG D+GG E WA+ +VG VQ A W+ MS + YLT L W + Sbjct 157 LASLIGERLRAAGRDSGGAEVWAHGLVGMVQSAGDWWLERRTMSRTAVTGYLTSLIWGGI 216 Query 206 CGIVEAGGSLEKF 218 G ++ G + ++F Sbjct 217 SGTLD-GATGDRF 228 >gi|257054735|ref|YP_003132567.1| transcriptional regulator [Saccharomonospora viridis DSM 43017] gi|256584607|gb|ACU95740.1| transcriptional regulator [Saccharomonospora viridis DSM 43017] Length=256 Score = 120 bits (302), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 68/204 (34%), Positives = 114/204 (56%), Gaps = 4/204 (1%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 D R+ RW +H++ RR E V+ ++A+ HG + M+E+AA GV+K VLYR+F DK DL Sbjct 25 DARRDRWRKHRIARRAEFVEAALKALDEHGPDMGMEELAAAAGVTKPVLYRHFADKADLY 84 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASK- 131 A+ R T+ L ++ A+++++ R + + + P YR ++ S K Sbjct 85 LALGQRGTE-ILFERLMPAINSELAPLPRIRMALTAFFSVIEEHPNLYRLLVRRSFGGKP 143 Query 132 --SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS 189 + V+A+ +++IA L +L M+ MD+G EPWA+ +VG VQ W+ MS Sbjct 144 VGTDVVAEDKQLIAAALTALLGDYMRMLNMDSGAAEPWAHGLVGMVQSTGEWWLDKRTMS 203 Query 190 SDELIDYLTMLSWSALCGIVEAGG 213 D +++YLT + W+A+ G+ G Sbjct 204 RDSVVEYLTQIIWAAIDGLTRQHG 227 >gi|315506143|ref|YP_004085030.1| regulatory protein TetR [Micromonospora sp. L5] gi|315412762|gb|ADU10879.1| regulatory protein TetR [Micromonospora sp. L5] Length=238 Score = 117 bits (292), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 69/204 (34%), Positives = 110/204 (54%), Gaps = 11/204 (5%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 ++ GR+ RW H+ +RR EL+ ++A+ +HG + MD++AA GVSK VLYRYF DK Sbjct 21 RSGGRRDRWADHREQRRQELIAAAVQALLQHGPSVDMDQVAATAGVSKPVLYRYFADKAQ 80 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREI----IRVYVETVAAQPEPYRFVMAN 126 L AV + ++AA++ ++ R + I Y+ V +P YRF++ Sbjct 81 LWLAV-----SEVVAERVVAAIAPAVEQVREERALVEATIDAYLSVVEYEPSLYRFLVHE 135 Query 127 SSASK-SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSD 185 S +V+ + R +A LA ++ R++ G+D G EPWAY +VG VQ W + Sbjct 136 SGHPGIQQVVTGTSRQVATGLARVIGDRLRALGLDAGPAEPWAYGLVGFVQAVGDWWTTH 195 Query 186 PR-MSSDELIDYLTMLSWSALCGI 208 + + L +YLT L WS + G+ Sbjct 196 GQPIHRAALTEYLTTLLWSGIEGV 219 >gi|302867447|ref|YP_003836084.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029] gi|302570306|gb|ADL46508.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029] Length=238 Score = 116 bits (291), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 69/204 (34%), Positives = 110/204 (54%), Gaps = 11/204 (5%) Query 11 KTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKND 70 ++ GR+ RW H+ +RR EL+ ++A+ +HG + MD++AA GVSK VLYRYF DK Sbjct 21 RSGGRRDRWADHREQRRQELIAAAVQALLQHGPSVDMDQVAATAGVSKPVLYRYFADKAQ 80 Query 71 LTTAVMMRFTQTTLIPNMIAALSADMDGFELTREI----IRVYVETVAAQPEPYRFVMAN 126 L AV + ++AA++ ++ R + I Y+ V +P YRF++ Sbjct 81 LWLAV-----SEVVAERVVAAIAPAVEQVREERALVEATIDAYLSVVEYEPSLYRFLVHE 135 Query 127 SSASK-SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSD 185 S +V+ + R +A LA ++ R++ G+D G EPWAY +VG VQ W + Sbjct 136 SGHPGIQQVVTGTSRQVATGLARVIGDRLRALGLDAGPAEPWAYGLVGFVQAVGDWWTTH 195 Query 186 PR-MSSDELIDYLTMLSWSALCGI 208 + + L +YLT L WS + G+ Sbjct 196 GQPIHRAALTEYLTTLLWSGIEGV 219 >gi|326331598|ref|ZP_08197888.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium Broad-1] gi|325950854|gb|EGD42904.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium Broad-1] Length=229 Score = 116 bits (290), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 71/198 (36%), Positives = 100/198 (51%), Gaps = 2/198 (1%) Query 10 VKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKN 69 VK DGR RW H+ RR ELV I A+ G +S+ +IAAE GVSK VLYRYF DK Sbjct 8 VKDDGRSSRWDAHREARRAELVAAAIRAVDSAGAEVSIADIAAEAGVSKPVLYRYFADKA 67 Query 70 DLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSA 129 +L AV M + ++ ++ A+ A + + YVET+A P Y ++ Sbjct 68 ELHAAVGM-WAARQILDAVVEAVLAPAPTRQRVEAGVAAYVETIAEHPNVY-LLLVRQHT 125 Query 130 SKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMS 189 + +AD +++IA A +L G+D G EPWA+ +VG + A W+ MS Sbjct 126 GGTDPLADGKQLIAATFARLLGDTFGRLGIDAAGAEPWAHSLVGIGESAGQWWLDRRTMS 185 Query 190 SDELIDYLTMLSWSALCG 207 YL+ W AL G Sbjct 186 RAAFARYLSEFVWHALEG 203 >gi|291300506|ref|YP_003511784.1| TetR family transcriptional regulator [Stackebrandtia nassauensis DSM 44728] gi|290569726|gb|ADD42691.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis DSM 44728] Length=213 Score = 114 bits (286), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 67/195 (35%), Positives = 102/195 (53%), Gaps = 2/195 (1%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 DGRK RW H+ RR ELV + AI R+G ++M+++AA V+K VLYR+F D+ +L Sbjct 16 DGRKGRWQAHRQARRLELVQAAVRAIHRNGPHINMNDVAAAAKVTKPVLYRHFADQRELY 75 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKS 132 AV ++ L+ + L + + E+ +I Y+ V +P YRFV+ + A ++ Sbjct 76 HAV-GQYAAEWLVAWLAQHLEPETEPTEVIATVIDAYLGAVETEPVLYRFVIRYAFADEA 134 Query 133 KVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSS-D 191 + I+ R + MLR R++ AGMD WA IVG VQ W+ P ++ Sbjct 135 NAVDGYRDIVVRHVDEMLRARLKAAGMDDSACHAWAQGIVGMVQSVGEWWLDRPDAATRP 194 Query 192 ELIDYLTMLSWSALC 206 +L LT L W L Sbjct 195 QLTQQLTALIWGGLS 209 >gi|317125017|ref|YP_004099129.1| TetR transcriptional regulator [Intrasporangium calvum DSM 43043] gi|315589105|gb|ADU48402.1| regulatory protein TetR [Intrasporangium calvum DSM 43043] Length=229 Score = 111 bits (278), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 76/213 (36%), Positives = 109/213 (52%), Gaps = 17/213 (7%) Query 12 TDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDL 71 TDGR RW +H+ ERR LVD TI AIRRHG + MD+IAAE G SKTV+YR+F D+ L Sbjct 12 TDGRTVRWARHREERRRSLVDATIRAIRRHGATVGMDDIAAEAGTSKTVIYRHFEDRAGL 71 Query 72 TTAVMMRFTQTTLIPNMIAAL----SADMDGFELTREIIRVYVETVAAQPEPYRFVMANS 127 AV R ++ + AAL +A D EL + Y+E V + E YRFV+ Sbjct 72 YRAVAQRV-DARVVGGIAAALERSSAAGKDPRELISSTVDAYLELVESDTELYRFVVNRP 130 Query 128 SASK-------SKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATH 180 + +++ ++R+L L + A D WA +VG VQ Sbjct 131 IVDRPLPDDPVGELVGHVTDQLSRLLDGRLGGEPRHA-PDPATTRVWAVALVGSVQAVAD 189 Query 181 SWMSDPRMSS----DELIDYLTMLSWSALCGIV 209 W++ P SS +L++ L+ L+W+ L I+ Sbjct 190 DWLAAPGTSSRPTRRDLVESLSELAWNGLSPIL 222 >gi|284988923|ref|YP_003407477.1| TetR family transcriptional regulator [Geodermatophilus obscurus DSM 43160] gi|284062168|gb|ADB73106.1| transcriptional regulator, TetR family [Geodermatophilus obscurus DSM 43160] Length=215 Score = 108 bits (269), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 64/195 (33%), Positives = 101/195 (52%), Gaps = 5/195 (2%) Query 19 WHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMR 78 W +H+ RR +LVD TI A+ RHG + M+EIA G SK V+YR+F D+++L AV R Sbjct 15 WDEHRRARREQLVDATITAVGRHGAGVGMEEIATAAGTSKAVVYRHFADRSELHVAVCAR 74 Query 79 FTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMAN---SSASKSKVI 135 L + A+ D ++ + Y+ + A E YRFV+ + S I Sbjct 75 VA-ANLTDRLREAMDTTTDPRQMLTAAVETYLAFLEADLELYRFVVQGPPVGHPADSDPI 133 Query 136 ADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWM-SDPRMSSDELI 194 A+ ++ A ++ +++AG D PW + +VG V+ A W+ +D M EL Sbjct 134 ANLSHLVGDQAAALVAVVLEQAGRDPAAARPWGHGLVGLVRSAADWWLQADRPMPRVELA 193 Query 195 DYLTMLSWSALCGIV 209 +LT L+W+ L G+V Sbjct 194 AHLTDLTWAGLSGVV 208 >gi|325000514|ref|ZP_08121626.1| TetR/AcrR family transcriptional regulator [Pseudonocardia sp. P1] Length=231 Score = 104 bits (259), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 58/181 (33%), Positives = 98/181 (55%), Gaps = 3/181 (1%) Query 30 LVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPNMI 89 +VD + AIR HG +S+ +IAA G++K VLYR+F D+ DL AV + L+ + Sbjct 21 MVDAAVGAIREHGPGVSVAQIAAAAGITKPVLYRHFADRADLQRAVGEHAAE-MLMERIS 79 Query 90 AALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSS--ASKSKVIADSERIIARMLA 147 L+ D + E +I ++ + +P YRFV++N + + ++V D I +L Sbjct 80 PVLAIDAEPIEHVAAVIDAFLGMIEDEPHLYRFVVSNPAEPTAGAEVAEDVRGRIGAVLT 139 Query 148 VMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDELIDYLTMLSWSALCG 207 + R++ G D+GG E WA+ ++G VQ A W+ MS + L +YL+ + W + G Sbjct 140 TLFGERLRAEGRDSGGAEVWAHGLIGMVQSAGDWWLDRRTMSREALTNYLSAIIWGGIAG 199 Query 208 I 208 + Sbjct 200 V 200 >gi|152967972|ref|YP_001363756.1| TetR family transcriptional regulator [Kineococcus radiotolerans SRS30216] gi|151362489|gb|ABS05492.1| transcriptional regulator, TetR family [Kineococcus radiotolerans SRS30216] Length=217 Score = 95.9 bits (237), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 66/201 (33%), Positives = 104/201 (52%), Gaps = 5/201 (2%) Query 13 DGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLT 72 DGR+ RW +H+ RR ELV + AI G + MDE+AA G SKTVLYR+F DK +L Sbjct 10 DGRRTRWDEHRRRRREELVTAALRAITAKGAGVGMDEVAAAAGTSKTVLYRHFADKEELY 69 Query 73 TAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKS 132 AV R + ++ + A++A + + II YV+ V A PE YRFV+++ + Sbjct 70 LAVADRV-NSRILRELGEAVAASANPRQALSGIIAAYVQLVEADPEVYRFVVSHPFLERP 128 Query 133 KVIADSERI---IARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDP-RM 188 +RI +A A + ++ G + A+ +V ++ A W+S P R+ Sbjct 129 LTSDPVQRISATVADETARTITAHLRVGGARDSSADALAHGLVALIRTAADRWISSPDRV 188 Query 189 SSDELIDYLTMLSWSALCGIV 209 + L+ LT L+W L ++ Sbjct 189 PAATLVSDLTHLAWGGLSTVL 209 >gi|325003475|ref|ZP_08124587.1| TetR family transcriptional regulator [Pseudonocardia sp. P1] Length=231 Score = 95.5 bits (236), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/220 (34%), Positives = 105/220 (48%), Gaps = 18/220 (8%) Query 7 AVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFV 66 +V + D R RW H+ ERR +LV I AIRR G + MDEIAA G SKTV+YR+F Sbjct 3 SVKMARDKRDSRWDAHREERRVQLVGSAIAAIRRTGAGIGMDEIAAAAGTSKTVIYRHFG 62 Query 67 DKNDLTTAVMMRFTQTTLIPNMIA---ALSADMDGFELTREI-IRVYVETVAAQPEPYRF 122 D+ L TA+ L A ALS D G + Y+ + PE YRF Sbjct 63 DRAGLYTAICESVAGVLLAEVRRATGEALSDDRLGPRAAVAAGVDAYLRLIEIDPELYRF 122 Query 123 VMANS---SASKSKVIADSE---------RIIARMLAVMLRRRMQEAGMDT-GGVEPWAY 169 V+ + ++ AD+E +I +AV++ + G D W + Sbjct 123 VVHRPLLVQGNGNRRSADTETPDPVNDLVTVIGDEIAVVIGDNLHTEGSDGHAAARFWGH 182 Query 170 LIVGGVQLATHSWMSDPRMSSDE-LIDYLTMLSWSALCGI 208 IVG V+ A W++ P ++ E L +LT L+WS L G+ Sbjct 183 AIVGLVRGAADDWLARPDGTTRERLTAHLTDLAWSGLSGL 222 >gi|84496320|ref|ZP_00995174.1| putative TetR-family transcriptional regulator [Janibacter sp. HTCC2649] gi|84383088|gb|EAP98969.1| putative TetR-family transcriptional regulator [Janibacter sp. HTCC2649] Length=259 Score = 92.8 bits (229), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 68/222 (31%), Positives = 102/222 (46%), Gaps = 27/222 (12%) Query 10 VKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKN 69 V DGR RW QH+ +RR ELV+ T+ AIR G + MD+IA G SKTV YR+F D+ Sbjct 27 VAVDGRSSRWDQHRAKRRTELVEATLRAIRSRGAGVGMDDIATVAGTSKTVYYRHFTDRA 86 Query 70 DLTTAVMMRFTQTTLIPNMIAALSADMDGF---------------ELTREIIRVYVETVA 114 L AV R +I I D+ F +L + Y+ V Sbjct 87 GLYGAVAERVNA--IILRDITRAVGDVGVFTAPLAETGSPTSSPRDLLAAAVDAYLALVE 144 Query 115 AQPEPYRFVMAN-----SSASKSKVIADS-ERIIARMLAVMLRRRMQEAGMDTGGVEPWA 168 PE YRF++A S +++ +A++ + +A + ++ +Q AG T W Sbjct 145 HDPEVYRFIVAAPLVPPSERTETIDLANTVSQAMALQIGSLIAVALQAAGRSTAPAATWG 204 Query 169 YLIVGGVQLATHSWM----SDPRMSSDELIDYLTMLSWSALC 206 +VG V+ A W+ + S + L ++LT L W L Sbjct 205 QAVVGMVRAAGDEWLRTGAAASTTSRETLKEHLTELIWGGLS 246 >gi|296164135|ref|ZP_06846751.1| transcriptional regulatory protein TetR [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900518|gb|EFG79908.1| transcriptional regulatory protein TetR [Mycobacterium parascrofulaceum ATCC BAA-614] Length=235 Score = 92.0 bits (227), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 62/216 (29%), Positives = 98/216 (46%), Gaps = 7/216 (3%) Query 1 VAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTV 60 V +P +T D R RW +H+ R EL++ T+ AI +G LS+D++ G+ + Sbjct 8 VGRLLPELT--GDARADRWREHRAAVRAELIEATLRAIDEYGPDLSIDDVVKTAGIPRPK 65 Query 61 LYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPY 120 LYR+F DK+ L AV R Q +I ++ A EL + YV V +P + Sbjct 66 LYRFFADKDALFAAVGQR-VQEMIIEQVVPQFDAATTALELVSSAVAAYVGLVDKRPNLF 124 Query 121 RFVMANSSASKSKVIAD---SERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQL 177 RF++ NS + AD R ++ + ++ G + E +G V L Sbjct 125 RFLV-NSHFRDGRSPADLIEGGRPLSDATVDVWSAAIEARGGEGANFEYVVDAALGAVGL 183 Query 178 ATHSWMSDPRMSSDELIDYLTMLSWSALCGIVEAGG 213 W++ P +S D L++ LT W A I E G Sbjct 184 GVLRWLNSPTVSKDALVEELTAFLWGAFSAIAEVRG 219 Lambda K H 0.321 0.133 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 313223274342 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40