BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0482 Length=369 Score E Sequences producing significant alignments: (Bits) Value gi|15607623|ref|NP_214996.1| UDP-N-acetylenolpyruvoylglucosamine... 733 0.0 gi|306774580|ref|ZP_07412917.1| UDP-N-acetylenolpyruvoylglucosam... 732 0.0 gi|298523960|ref|ZP_07011369.1| UDP-N-acetylenolpyruvoylglucosam... 731 0.0 gi|254230830|ref|ZP_04924157.1| UDP-N-acetylenolpyruvoylglucosam... 634 7e-180 gi|15828323|ref|NP_302586.1| UDP-N-acetylenolpyruvoylglucosamine... 565 4e-159 gi|183980832|ref|YP_001849123.1| UDP-N-acetylenolpyruvoylglucosa... 549 3e-154 gi|254819810|ref|ZP_05224811.1| UDP-N-acetylenolpyruvoylglucosam... 548 6e-154 gi|240169865|ref|ZP_04748524.1| UDP-N-acetylenolpyruvoylglucosam... 545 3e-153 gi|296168084|ref|ZP_06850150.1| UDP-N-acetylmuramate dehydrogena... 541 5e-152 gi|118619645|ref|YP_907977.1| UDP-N-acetylenolpyruvoylglucosamin... 540 2e-151 gi|342859016|ref|ZP_08715670.1| UDP-N-acetylenolpyruvoylglucosam... 532 3e-149 gi|307082967|ref|ZP_07492080.1| putative FAD binding domain prot... 529 4e-148 gi|118462379|ref|YP_883797.1| UDP-N-acetylenolpyruvoylglucosamin... 521 1e-145 gi|41410073|ref|NP_962909.1| UDP-N-acetylenolpyruvoylglucosamine... 517 1e-144 gi|120401838|ref|YP_951667.1| UDP-N-acetylenolpyruvoylglucosamin... 479 3e-133 gi|167970695|ref|ZP_02552972.1| UDP-N-acetylenolpyruvoylglucosam... 473 3e-131 gi|118473099|ref|YP_885331.1| UDP-N-acetylenolpyruvoylglucosamin... 458 7e-127 gi|108797633|ref|YP_637830.1| UDP-N-acetylenolpyruvoylglucosamin... 456 3e-126 gi|333989111|ref|YP_004521725.1| UDP-N-acetylenolpyruvoylglucosa... 455 5e-126 gi|126433257|ref|YP_001068948.1| UDP-N-acetylenolpyruvoylglucosa... 455 6e-126 gi|315442352|ref|YP_004075231.1| UDP-N-acetylenolpyruvoylglucosa... 453 2e-125 gi|145220696|ref|YP_001131374.1| UDP-N-acetylenolpyruvoylglucosa... 449 3e-124 gi|307082968|ref|ZP_07492081.1| putative UDP-N-acetylmuramate de... 408 6e-112 gi|169631144|ref|YP_001704793.1| UDP-N-acetylenolpyruvoylglucosa... 377 2e-102 gi|226361172|ref|YP_002778950.1| UDP-N-acetylenolpyruvoylglucosa... 352 4e-95 gi|325674045|ref|ZP_08153735.1| UDP-N-acetylmuramate dehydrogena... 350 3e-94 gi|312141134|ref|YP_004008470.1| UDP-N-acetylenolpyruvoylglucosa... 349 3e-94 gi|54027171|ref|YP_121413.1| UDP-N-acetylenolpyruvoylglucosamine... 348 7e-94 gi|229490523|ref|ZP_04384361.1| UDP-N-acetylenolpyruvoylglucosam... 348 9e-94 gi|226305090|ref|YP_002765048.1| UDP-N-acetylenolpyruvoylglucosa... 348 1e-93 gi|302523810|ref|ZP_07276152.1| UDP-N-acetylenolpyruvoylglucosam... 345 6e-93 gi|111019079|ref|YP_702051.1| UDP-N-acetylenolpyruvoylglucosamin... 341 1e-91 gi|333918293|ref|YP_004491874.1| UDP-N-acetylenolpyruvoylglucosa... 329 4e-88 gi|227541623|ref|ZP_03971672.1| UDP-N-acetylenolpyruvoylglucosam... 328 8e-88 gi|134103404|ref|YP_001109065.1| UDP-N-acetylenolpyruvoylglucosa... 328 1e-87 gi|291006056|ref|ZP_06564029.1| UDP-N-acetylmuramate dehydrogena... 328 1e-87 gi|319949960|ref|ZP_08023951.1| UDP-N-acetylenolpyruvoylglucosam... 327 2e-87 gi|343925757|ref|ZP_08765272.1| UDP-N-acetylenolpyruvoylglucosam... 327 2e-87 gi|227487207|ref|ZP_03917523.1| UDP-N-acetylenolpyruvoylglucosam... 326 4e-87 gi|300782383|ref|YP_003762674.1| UDP-N-acetylmuramate dehydrogen... 325 6e-87 gi|296141320|ref|YP_003648563.1| UDP-N-acetylenolpyruvoylglucosa... 323 3e-86 gi|326384040|ref|ZP_08205723.1| UDP-N-acetylenolpyruvoylglucosam... 322 8e-86 gi|311740992|ref|ZP_07714817.1| UDP-N-acetylmuramate dehydrogena... 319 4e-85 gi|161485999|ref|NP_737027.2| UDP-N-acetylenolpyruvoylglucosamin... 315 8e-84 gi|145294515|ref|YP_001137336.1| UDP-N-acetylenolpyruvoylglucosa... 314 2e-83 gi|29336782|sp|Q8NTB0.1|MURB2_CORGL RecName: Full=UDP-N-acetylen... 313 2e-83 gi|19551643|ref|NP_599645.1| UDP-N-acetylenolpyruvoylglucosamine... 313 2e-83 gi|23492253|dbj|BAC17227.1| putative UDP-N-acetylenolpyruvoylglu... 313 3e-83 gi|255324233|ref|ZP_05365355.1| UDP-N-acetylmuramate dehydrogena... 313 4e-83 gi|227505613|ref|ZP_03935662.1| UDP-N-acetylenolpyruvoylglucosam... 310 3e-82 >gi|15607623|ref|NP_214996.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium tuberculosis H37Rv] gi|15839872|ref|NP_334909.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium tuberculosis CDC1551] gi|31791662|ref|NP_854155.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium bovis AF2122/97] 73 more sequence titles Length=369 Score = 733 bits (1892), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/369 (100%), Positives = 369/369 (100%), Gaps = 0/369 (0%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA Sbjct 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 Query 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG Sbjct 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 Query 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL Sbjct 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 Query 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR Sbjct 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 Query 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL Sbjct 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP Sbjct 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 Query 361 EPVLIGCML 369 EPVLIGCML Sbjct 361 EPVLIGCML 369 >gi|306774580|ref|ZP_07412917.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium tuberculosis SUMu001] gi|306970684|ref|ZP_07483345.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium tuberculosis SUMu010] gi|307078408|ref|ZP_07487578.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium tuberculosis SUMu011] gi|308216926|gb|EFO76325.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium tuberculosis SUMu001] gi|308359805|gb|EFP48656.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium tuberculosis SUMu010] gi|308363648|gb|EFP52499.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium tuberculosis SUMu011] Length=369 Score = 732 bits (1890), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/369 (99%), Positives = 369/369 (100%), Gaps = 0/369 (0%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA Sbjct 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 Query 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG Sbjct 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 Query 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL Sbjct 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 Query 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALN+TSGERADPQAVREAVLALRAR Sbjct 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNSTSGERADPQAVREAVLALRAR 240 Query 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL Sbjct 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP Sbjct 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 Query 361 EPVLIGCML 369 EPVLIGCML Sbjct 361 EPVLIGCML 369 >gi|298523960|ref|ZP_07011369.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium tuberculosis 94_M4241A] gi|298493754|gb|EFI29048.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium tuberculosis 94_M4241A] Length=369 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/369 (99%), Positives = 368/369 (99%), Gaps = 0/369 (0%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIAR VITCTSAEQVVAALRHLDSAAKTGA Sbjct 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARSVITCTSAEQVVAALRHLDSAAKTGA 60 Query 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG Sbjct 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 Query 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL Sbjct 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 Query 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR Sbjct 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 Query 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL Sbjct 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP Sbjct 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 Query 361 EPVLIGCML 369 EPVLIGCML Sbjct 361 EPVLIGCML 369 >gi|254230830|ref|ZP_04924157.1| UDP-N-acetylenolpyruvoylglucosamine reductase murB [Mycobacterium tuberculosis C] gi|124599889|gb|EAY58899.1| UDP-N-acetylenolpyruvoylglucosamine reductase murB [Mycobacterium tuberculosis C] Length=351 Score = 634 bits (1635), Expect = 7e-180, Method: Compositional matrix adjust. Identities = 323/339 (96%), Positives = 324/339 (96%), Gaps = 0/339 (0%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA Sbjct 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 Query 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG Sbjct 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 Query 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL Sbjct 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 Query 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR Sbjct 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 Query 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL Sbjct 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWL 300 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDV 339 VERAGFGKGYPDAGAAPCR + AEDV Sbjct 301 VERAGFGKGYPDAGAAPCRAFHQTCAGADKSWRGNAEDV 339 >gi|15828323|ref|NP_302586.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium leprae TN] gi|221230800|ref|YP_002504216.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium leprae Br4923] gi|18202750|sp|Q9CB48.1|MURB_MYCLE RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|254764215|sp|B8ZT90.1|MURB_MYCLB RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|13094016|emb|CAC31964.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium leprae] gi|219933907|emb|CAR72546.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium leprae Br4923] Length=367 Score = 565 bits (1456), Expect = 4e-159, Method: Compositional matrix adjust. Identities = 294/372 (80%), Positives = 317/372 (86%), Gaps = 8/372 (2%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDS-AAKTG 59 MKRS VGS FAGAH+AEAV LAPLTTLRVGP+A+RVITC S EQVV +R LD+ A G Sbjct 1 MKRSAVGSFFAGAHVAEAVSLAPLTTLRVGPVAQRVITCASTEQVVDVIRQLDAPAGGRG 60 Query 60 ADRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 A L+FAGGSNLVIA+ L DLT VRLAN+GITIDGNLVRAEAGAV+DDVVVRAIE GLG Sbjct 61 AGPLLIFAGGSNLVIADTLADLTAVRLANAGITIDGNLVRAEAGAVWDDVVVRAIEHGLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLL+R +G VRWVSA +LRFGYRTSV Sbjct 121 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLERSSGSVRWVSACELRFGYRTSV 180 Query 180 LKHAD--GLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLAL 237 K AD G P VVLEVEF LD SG+SAPL YGEL+A L+ATSG+RA+P AVREAVLAL Sbjct 181 FKQADPSGSQPPAVVLEVEFKLDASGQSAPLHYGELVATLDATSGQRANPHAVREAVLAL 240 Query 238 RARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAA 297 R RKGMVLD DHDTWSVGSFFTNPVV DVY +L A DGPVPHYPA DGVKLAA Sbjct 241 RVRKGMVLDAADHDTWSVGSFFTNPVVAPDVYRQL----AKMVDGPVPHYPAQDGVKLAA 296 Query 298 GWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGIT 357 GWLVERAGFGKGYPD GAAPCRLSTKH LALTNRG ATAEDVVTLAR VR+GV +VFGIT Sbjct 297 GWLVERAGFGKGYPD-GAAPCRLSTKHVLALTNRGAATAEDVVTLARTVRNGVLEVFGIT 355 Query 358 LKPEPVLIGCML 369 L+PEP L+GC+L Sbjct 356 LEPEPALVGCVL 367 >gi|183980832|ref|YP_001849123.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium marinum M] gi|254764226|sp|B2HQU8.1|MURB_MYCMM RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|183174158|gb|ACC39268.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium marinum M] Length=366 Score = 549 bits (1414), Expect = 3e-154, Method: Compositional matrix adjust. Identities = 284/370 (77%), Positives = 309/370 (84%), Gaps = 5/370 (1%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKR VGSLFAGA +AE+VPLAPLTTLRVGP+AR ++TC + +QVV LR LD A+ G Sbjct 1 MKRRDVGSLFAGARVAESVPLAPLTTLRVGPVARTLVTCDTTDQVVGVLRELDDRARNGD 60 Query 61 DRP-LVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 P LVFAGGSN+VI + L DLTVVR+AN +TIDGNLVRAEAGAV+D+VVV AIE+GLG Sbjct 61 CGPVLVFAGGSNVVIGDALADLTVVRVANDRVTIDGNLVRAEAGAVWDEVVVAAIERGLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATPVQNVGAYG EVSD ITRVRLLDR TGEV WV A DL FGYRTSV Sbjct 121 GLECLSGIPGSAGATPVQNVGAYGVEVSDVITRVRLLDRSTGEVSWVPAADLSFGYRTSV 180 Query 180 LKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRA 239 LK ADGLA+P VVLEVEFALD SGRSAPLRYGEL AAL SGER +P+AVR+AVLALRA Sbjct 181 LKQADGLALPAVVLEVEFALDASGRSAPLRYGELTAALGMNSGERGEPRAVRDAVLALRA 240 Query 240 RKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGW 299 RKGMVLD DHDTWSVGSFFTNPVV ++YERLA VPHYPAPDGVKLAAGW Sbjct 241 RKGMVLDAADHDTWSVGSFFTNPVVAPEIYERLAAQTGES----VPHYPAPDGVKLAAGW 296 Query 300 LVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLK 359 L+ERAGFGKGYP A CRLS+KHALALTNRGGATA DV+ LAR VRDGV DVFGITLK Sbjct 297 LLERAGFGKGYPGDPHARCRLSSKHALALTNRGGATAADVMVLARTVRDGVRDVFGITLK 356 Query 360 PEPVLIGCML 369 PEPVL+GC L Sbjct 357 PEPVLVGCAL 366 >gi|254819810|ref|ZP_05224811.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium intracellulare ATCC 13950] Length=372 Score = 548 bits (1412), Expect = 6e-154, Method: Compositional matrix adjust. Identities = 282/376 (75%), Positives = 317/376 (85%), Gaps = 11/376 (2%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MK SG GS+FAGA +A++ PLAPLTTLR+GPIARR++TCT+++QVVAAL HLD+ ++ G Sbjct 1 MKSSGAGSVFAGASVADSAPLAPLTTLRIGPIARRLVTCTNSDQVVAALGHLDAESRAGQ 60 Query 61 DRP-LVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 P LVFAGGSNLVI++ DLT V+LAN GIT+DGNL+RA+AGAV+DDV + AIE GLG Sbjct 61 GGPVLVFAGGSNLVISDTCADLTAVKLANDGITVDGNLIRAQAGAVWDDVALAAIEHGLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRV++LDR TGEVRWV +L FGYRTSV Sbjct 121 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVKVLDRGTGEVRWVPGGELGFGYRTSV 180 Query 180 LKH--ADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLAL 237 K A G +P+VVLEVEFALD SGRSAPLRY EL AALN GERA+P+AVREAVLAL Sbjct 181 FKRGGAGGFEIPSVVLEVEFALDASGRSAPLRYAELAAALNVGVGERAEPRAVREAVLAL 240 Query 238 RARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAA 297 RARKGMVLDP DHDTWSVGSFFTNPVV +VYERLA DGPVP+YPAPDGVKLAA Sbjct 241 RARKGMVLDPADHDTWSVGSFFTNPVVAPEVYERLAATV----DGPVPNYPAPDGVKLAA 296 Query 298 GWLVERAGFGKGYPDAG----AAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDV 353 GWLVERAGF KGYP+ G APCRLSTKHALALTNRGGA A+DV+ LARAVRDGV DV Sbjct 297 GWLVERAGFAKGYPEPGPGGREAPCRLSTKHALALTNRGGARADDVIALARAVRDGVADV 356 Query 354 FGITLKPEPVLIGCML 369 FG+TL PEPVL+GC L Sbjct 357 FGVTLIPEPVLLGCRL 372 >gi|240169865|ref|ZP_04748524.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium kansasii ATCC 12478] Length=370 Score = 545 bits (1405), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 285/374 (77%), Positives = 311/374 (84%), Gaps = 9/374 (2%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MK S VG+ FAGA + E+VPLA LTTLRVGP+ARRVITC +++QVVA LR LD+ + Sbjct 1 MKWSAVGARFAGARVEESVPLAALTTLRVGPVARRVITCATSDQVVAVLRQLDAEVRADN 60 Query 61 DRP-LVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 P LVFAGGSN+VI + + DLTVVRLAN+GIT+DGNLVRAEAGAV+DDVV +AI+ LG Sbjct 61 GGPVLVFAGGSNVVIGDAVADLTVVRLANAGITVDGNLVRAEAGAVWDDVVRKAIDHRLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATPVQNVGAYG EVSD I+RVRLLDR +G+V WV L FGYRTSV Sbjct 121 GLECLSGIPGSAGATPVQNVGAYGVEVSDVISRVRLLDRSSGQVDWVPGAALGFGYRTSV 180 Query 180 LKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRA 239 LK ADGL +P VVLEVEFALD SGRSAPLRYGEL AAL SGERADPQAVR AVLALRA Sbjct 181 LKQADGLRLPAVVLEVEFALDASGRSAPLRYGELTAALGVASGERADPQAVRAAVLALRA 240 Query 240 RKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGW 299 RKGMVLDPTDHDTWSVGSFFTNPVV DVYERL A ++GPVPHYPAP GVKLAAGW Sbjct 241 RKGMVLDPTDHDTWSVGSFFTNPVVAPDVYERL----AAAENGPVPHYPAPGGVKLAAGW 296 Query 300 LVERAGFGKGYPDAG----AAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFG 355 LVE AGFGKGYPD AAPCRLSTKHALALTNRG ATA DV+ LAR VRDGV DVFG Sbjct 297 LVEHAGFGKGYPDPALTGQAAPCRLSTKHALALTNRGTATAADVMLLARMVRDGVRDVFG 356 Query 356 ITLKPEPVLIGCML 369 ITL+PEP+LIGC L Sbjct 357 ITLEPEPILIGCRL 370 >gi|296168084|ref|ZP_06850150.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896891|gb|EFG76519.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=368 Score = 541 bits (1395), Expect = 5e-152, Method: Compositional matrix adjust. Identities = 280/372 (76%), Positives = 307/372 (83%), Gaps = 7/372 (1%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MK S GS FAGA +AEAVPLAPLTTLRVGP+ARR+ITC S EQVVA ++ LD+ + G Sbjct 1 MKSSDAGSTFAGAQVAEAVPLAPLTTLRVGPVARRLITCASTEQVVAVVQELDAENRGGQ 60 Query 61 DRP-LVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 P LVFAGGSNLV+A+ LT VRLAN G+T+DGN VRAEAGAV+DDVVV +IE GLG Sbjct 61 RSPVLVFAGGSNLVVADTCAGLTAVRLANGGVTVDGNRVRAEAGAVWDDVVVSSIEHGLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATP+QNVGAYGAEVSDTITRVR+LDR +GEVRWV +L FGYRTSV Sbjct 121 GLECLSGIPGSAGATPIQNVGAYGAEVSDTITRVRILDRSSGEVRWVPGDELGFGYRTSV 180 Query 180 LKHA--DGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLAL 237 K A DG +P VVLEVEF LD SGRSAPLRYGEL AAL GERADP+AVR AVLAL Sbjct 181 FKRAGRDGAQIPWVVLEVEFELDASGRSAPLRYGELAAALEVGGGERADPRAVRRAVLAL 240 Query 238 RARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAA 297 R RKGMVLDP DHDTWSVGSFFTNPVV DVYERLA +GPVPHYPAPDGVKLAA Sbjct 241 RGRKGMVLDPDDHDTWSVGSFFTNPVVHPDVYERLAAAV----EGPVPHYPAPDGVKLAA 296 Query 298 GWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGIT 357 GWLVERAGF KG+P AA CRLSTKHALALTNRGGATA+DV+ LAR +RDGVH VFG+T Sbjct 297 GWLVERAGFAKGFPFDPAARCRLSTKHALALTNRGGATADDVIALARVIRDGVHAVFGVT 356 Query 358 LKPEPVLIGCML 369 L+PEPVL+GC L Sbjct 357 LEPEPVLLGCRL 368 >gi|118619645|ref|YP_907977.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium ulcerans Agy99] gi|166222843|sp|A0PVY7.1|MURB_MYCUA RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|118571755|gb|ABL06506.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium ulcerans Agy99] Length=366 Score = 540 bits (1391), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 278/370 (76%), Positives = 306/370 (83%), Gaps = 5/370 (1%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKR VGSLFAGA +AE+VPLAPLTTLRVGP+AR ++TC + +QVV LR LD A+ G Sbjct 1 MKRRDVGSLFAGARVAESVPLAPLTTLRVGPVARTLVTCDTTDQVVGVLRELDDRARNGD 60 Query 61 DRP-LVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 P LVFAGGSN+VI + L DLTVVR+AN +T+DGNLVRAEAG V+D+VVV IE+GLG Sbjct 61 CGPVLVFAGGSNVVIGDALADLTVVRVANDRVTVDGNLVRAEAGTVWDEVVVATIERGLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATPVQNVGAYG EVSD ITRVRLLDR TG+V WV A DL FGYRTSV Sbjct 121 GLECLSGIPGSAGATPVQNVGAYGVEVSDVITRVRLLDRSTGDVSWVPAADLSFGYRTSV 180 Query 180 LKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRA 239 LK A+GLA+P VVLEVEFALD SGRSAPLRYGEL AAL SGER +P+AVR+AVLALR Sbjct 181 LKQAEGLALPAVVLEVEFALDASGRSAPLRYGELTAALGMNSGERGEPRAVRDAVLALRT 240 Query 240 RKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGW 299 RKGMVLD DHDTWSVGSFFTNPVV ++YERLA VPHYPAPDGVKLAAGW Sbjct 241 RKGMVLDAADHDTWSVGSFFTNPVVAPEIYERLAAQTGES----VPHYPAPDGVKLAAGW 296 Query 300 LVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLK 359 L+ERAGFGKGYP A CRLS+KHALALTNRGGATA DV+ LAR VRDGV DVFGITLK Sbjct 297 LLERAGFGKGYPGDPHARCRLSSKHALALTNRGGATAADVMVLARTVRDGVRDVFGITLK 356 Query 360 PEPVLIGCML 369 PEPVL+GC L Sbjct 357 PEPVLVGCAL 366 >gi|342859016|ref|ZP_08715670.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium colombiense CECT 3035] gi|342133257|gb|EGT86460.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium colombiense CECT 3035] Length=367 Score = 532 bits (1371), Expect = 3e-149, Method: Compositional matrix adjust. Identities = 284/371 (77%), Positives = 312/371 (85%), Gaps = 6/371 (1%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 M SG GS FAGA +A+A PLAPLTTLRVGP ARR+ITCT++EQV+A LR LD+ G Sbjct 1 MNSSGAGSEFAGAAVADAAPLAPLTTLRVGPTARRLITCTTSEQVIATLRQLDAETAGGQ 60 Query 61 -DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLG 119 D L+FAGGSNLVI++ LT LT VRLAN+G++++GNLVRA+AGAV+DDVVV AIE GLG Sbjct 61 RDSVLIFAGGSNLVISDALTGLTAVRLANAGVSVEGNLVRAQAGAVWDDVVVTAIEHGLG 120 Query 120 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSV 179 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVR+LDR +GEVRW+ L FGYRTSV Sbjct 121 GLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRVLDRRSGEVRWMPGGQLGFGYRTSV 180 Query 180 LKH-ADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALR 238 K DGL +P+VVLEVEFALD SGRSAPLRYGEL AALN GERADPQAVREAVLALR Sbjct 181 FKRGGDGLEIPSVVLEVEFALDASGRSAPLRYGELAAALNVAPGERADPQAVREAVLALR 240 Query 239 ARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAG 298 ARKGMVLDP DHDTWSVGSFFTNPVV DVY+RLA DGPVP+YPAPDGVKLAAG Sbjct 241 ARKGMVLDPADHDTWSVGSFFTNPVVAPDVYQRLAASV----DGPVPNYPAPDGVKLAAG 296 Query 299 WLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITL 358 WLVE AGFGKGYPD A CRLSTKHALALTNRGGA ++DV+ LARAVRDGV VFGITL Sbjct 297 WLVEHAGFGKGYPDDANARCRLSTKHALALTNRGGAGSDDVIALARAVRDGVRAVFGITL 356 Query 359 KPEPVLIGCML 369 PEPVL+GC L Sbjct 357 VPEPVLLGCRL 367 >gi|307082967|ref|ZP_07492080.1| putative FAD binding domain protein [Mycobacterium tuberculosis SUMu012] gi|308367310|gb|EFP56161.1| putative FAD binding domain protein [Mycobacterium tuberculosis SUMu012] Length=268 Score = 529 bits (1362), Expect = 4e-148, Method: Compositional matrix adjust. Identities = 268/268 (100%), Positives = 268/268 (100%), Gaps = 0/268 (0%) Query 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA Sbjct 1 MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGA 60 Query 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG Sbjct 61 DRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGG 120 Query 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL Sbjct 121 LECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVL 180 Query 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR Sbjct 181 KHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRAR 240 Query 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDV 268 KGMVLDPTDHDTWSVGSFFTNPVVTQDV Sbjct 241 KGMVLDPTDHDTWSVGSFFTNPVVTQDV 268 >gi|118462379|ref|YP_883797.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium avium 104] gi|254777105|ref|ZP_05218621.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium avium subsp. avium ATCC 25291] gi|166222840|sp|A0QLK9.1|MURB_MYCA1 RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|118163666|gb|ABK64563.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium avium 104] Length=372 Score = 521 bits (1341), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 272/360 (76%), Positives = 300/360 (84%), Gaps = 11/360 (3%) Query 17 EAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRP-LVFAGGSNLVIA 75 +AVPLAPLTTLRVGP ARR+ITC S+EQV+A LR LD+ G P LVFAGGSNLVI+ Sbjct 17 DAVPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQRDPVLVFAGGSNLVIS 76 Query 76 ENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATP 135 + L+DLT VRLAN GIT++GNLVRA+AGAV+DDVV+ AIE GLGGLECLSGIPGSAGATP Sbjct 77 DALSDLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATP 136 Query 136 VQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHA--DGLAVPTVVL 193 +QNVGAYGAEVSDT+TRVR+LDR +G+VRWV +L FGYRTSV K DGL +P+VVL Sbjct 137 IQNVGAYGAEVSDTLTRVRVLDRGSGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVL 196 Query 194 EVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTW 253 EVEFALD SGRSAP+RYGEL A L GERADP+AVREAVLALRARKGMVLD DHDTW Sbjct 197 EVEFALDASGRSAPVRYGELAAELEVPVGERADPRAVREAVLALRARKGMVLDAADHDTW 256 Query 254 SVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGY--P 311 SVGSFFTNPVV DVYERLAG DGPVPHYPAP GVKLAAGWLVERAGFGKGY P Sbjct 257 SVGSFFTNPVVAPDVYERLAGSV----DGPVPHYPAPGGVKLAAGWLVERAGFGKGYPVP 312 Query 312 DAGA--APCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 D G APCRLSTKHALALTNRG A ++DV+ LAR +RDGV VFGITL PEPVL+GC L Sbjct 313 DPGGPEAPCRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL 372 >gi|41410073|ref|NP_962909.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium avium subsp. paratuberculosis K-10] gi|81413072|sp|Q73SU8.1|MURB_MYCPA RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|41398906|gb|AAS06525.1| MurB [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460436|gb|EGO39333.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium avium subsp. paratuberculosis S397] Length=372 Score = 517 bits (1331), Expect = 1e-144, Method: Compositional matrix adjust. Identities = 269/360 (75%), Positives = 298/360 (83%), Gaps = 11/360 (3%) Query 17 EAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRP-LVFAGGSNLVIA 75 +A PLAPLTTLRVGP ARR+ITC S+EQV+A LR LD+ G P LVFAGGSNLVI+ Sbjct 17 DAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQRDPVLVFAGGSNLVIS 76 Query 76 ENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATP 135 + L+DLT VRLAN GIT++GNLVRA+AGAV+DDVV+ AIE GLGGLECLSGIPGSAGATP Sbjct 77 DALSDLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATP 136 Query 136 VQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHA--DGLAVPTVVL 193 +QNVGAYGAEVSDT+TRVR+LDR +G+VRWV +L FGYRTSV K DGL +P+VVL Sbjct 137 IQNVGAYGAEVSDTLTRVRVLDRGSGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVL 196 Query 194 EVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTW 253 EVEFALD SGRSAP+RYGEL A L G+RADP+ VREAVLALRARKGMVLD DHDTW Sbjct 197 EVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLALRARKGMVLDAADHDTW 256 Query 254 SVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGY--P 311 SVGSFFTNPVV DVYERLAG DGPVPHYPAP GVKLAAGWLVERAGFGKGY P Sbjct 257 SVGSFFTNPVVAPDVYERLAGSV----DGPVPHYPAPGGVKLAAGWLVERAGFGKGYPVP 312 Query 312 DAGA--APCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 D G APCRLSTKHALALTNRG A ++DV+ LAR +RDGV VFGITL PEPVL+GC L Sbjct 313 DPGGPEAPCRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL 372 >gi|120401838|ref|YP_951667.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium vanbaalenii PYR-1] gi|119954656|gb|ABM11661.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium vanbaalenii PYR-1] Length=345 Score = 479 bits (1234), Expect = 3e-133, Method: Compositional matrix adjust. Identities = 255/358 (72%), Positives = 283/358 (80%), Gaps = 16/358 (4%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 G AE VPLAPLTTLRVGP+ARR+ITC + EQ+ A+R G D L+ AGGSN Sbjct 4 GVPFAEQVPLAPLTTLRVGPVARRLITCVATEQIGPAVR------AAGPD-ALILAGGSN 56 Query 72 LVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSA 131 +VIA++L DLTVVRLAN+GI +DG +VRAEAGAV+DDVV ++ QGLGGLECLSGIPGSA Sbjct 57 VVIADDLADLTVVRLANTGIVVDGAVVRAEAGAVWDDVVAASLTQGLGGLECLSGIPGSA 116 Query 132 GATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTV 191 GATPVQNVGAYGAEVSDTI RVRLLDR TG+ RWV+ L+FGYRTS+LK + V Sbjct 117 GATPVQNVGAYGAEVSDTIRRVRLLDRSTGDDRWVNPDFLQFGYRTSILKKSSAW----V 172 Query 192 VLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHD 251 VLEVEFALD SGRSAPLRYGEL A LNA GER DP VR AVL+LRARKGMVLD DHD Sbjct 173 VLEVEFALDASGRSAPLRYGELAAELNAEPGERVDPAQVRAAVLSLRARKGMVLDAADHD 232 Query 252 TWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYP 311 TWSVGSFFTNPVV++ +++LA DGPVP+YPAPDGVKLAAGWLVERAGFGKGYP Sbjct 233 TWSVGSFFTNPVVSRAEFDQLAASV----DGPVPNYPAPDGVKLAAGWLVERAGFGKGYP 288 Query 312 DAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 D AP RLSTKHALALTNRG AT DV+ LAR VRDGV FGI L PEPVLIGC L Sbjct 289 D-DEAPARLSTKHALALTNRGTATTADVIALARTVRDGVRAAFGIELTPEPVLIGCSL 345 >gi|167970695|ref|ZP_02552972.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium tuberculosis H37Ra] Length=234 Score = 473 bits (1216), Expect = 3e-131, Method: Compositional matrix adjust. Identities = 233/234 (99%), Positives = 234/234 (100%), Gaps = 0/234 (0%) Query 136 VQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEV 195 +QNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEV Sbjct 1 MQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEV 60 Query 196 EFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSV 255 EFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSV Sbjct 61 EFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSV 120 Query 256 GSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGA 315 GSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGA Sbjct 121 GSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGA 180 Query 316 APCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 APCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML Sbjct 181 APCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 234 >gi|118473099|ref|YP_885331.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium smegmatis str. MC2 155] gi|187609729|sp|A0QQZ3.1|MURB_MYCS2 RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|118174386|gb|ABK75282.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium smegmatis str. MC2 155] Length=363 Score = 458 bits (1178), Expect = 7e-127, Method: Compositional matrix adjust. Identities = 251/367 (69%), Positives = 287/367 (79%), Gaps = 15/367 (4%) Query 8 SLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPL-VF 66 S AG IAEAVPLAPLTTLR+GP+ARR++TCTS EQ++ LR L T D PL + Sbjct 4 SHVAGVEIAEAVPLAPLTTLRIGPVARRMLTCTSTEQLIGVLRAL-----TADDEPLLIL 58 Query 67 AGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSG 126 AGGSN+V+A++LTDLTVVR+AN+ IT+DG+ VRAEAGA++DDVVV ++ GLGGLECLSG Sbjct 59 AGGSNVVLADDLTDLTVVRIANTEITVDGDRVRAEAGALWDDVVVTSLAHGLGGLECLSG 118 Query 127 IPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGL 186 IPGSAGATPVQNVGAYGAEV+DTITRVRLLDR TGE RW + +LRFGYRTSVLKH+D + Sbjct 119 IPGSAGATPVQNVGAYGAEVADTITRVRLLDRRTGEDRWATTEELRFGYRTSVLKHSDAV 178 Query 187 AVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVL- 245 +VLEVEF LD +GRSAP+RY EL AL GER DP VR+AVL LR KGMV+ Sbjct 179 ----IVLEVEFGLDAAGRSAPVRYRELATALGVEPGERTDPLRVRDAVLRLRTGKGMVVD 234 Query 246 ---DPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVE 302 D DHDTWSVGSFFTNPVVT +ER+ A GPVP+YPAPDGVKLAAGWLVE Sbjct 235 PDPDHPDHDTWSVGSFFTNPVVTHADFERVERIARDAGAGPVPNYPAPDGVKLAAGWLVE 294 Query 303 RAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEP 362 RAGFGKGYP GA RLSTKHALALTNRG AT DV+ LA VR GV DVFGI L PEP Sbjct 295 RAGFGKGYPGEGAR-ARLSTKHALALTNRGQATTADVMALAGTVRAGVLDVFGIELTPEP 353 Query 363 VLIGCML 369 +L+GC+L Sbjct 354 ILLGCVL 360 >gi|108797633|ref|YP_637830.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium sp. MCS] gi|119866720|ref|YP_936672.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium sp. KMS] gi|123179555|sp|Q1BEB0.1|MURB_MYCSS RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|187609731|sp|A1UAM4.1|MURB_MYCSK RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|108768052|gb|ABG06774.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium sp. MCS] gi|119692809|gb|ABL89882.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium sp. KMS] Length=350 Score = 456 bits (1173), Expect = 3e-126, Method: Compositional matrix adjust. Identities = 248/363 (69%), Positives = 278/363 (77%), Gaps = 15/363 (4%) Query 7 GSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVF 66 G AGA + V LAPLTTLRVGP+ARR+IT TS EQ+VAALR A G D L+ Sbjct 3 GQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALR-----APVGRD-ALIL 56 Query 67 AGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSG 126 AGGSN+V+A++++DLTV+R+ANS IT+ +VRAEAGA +DDVVV A+ GLGGLECLSG Sbjct 57 AGGSNVVLADDMSDLTVIRVANSEITVRDGIVRAEAGANWDDVVVTALAHGLGGLECLSG 116 Query 127 IPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGL 186 IPGSAGATPVQNVGAYG+EV+DTI RVRL DR TG WV+ +D+ FGYRTSVLKH+D Sbjct 117 IPGSAGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQDMAFGYRTSVLKHSDH- 175 Query 187 AVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLD 246 VVLEVEFALD GRSAPLRYGEL AL+ G RADP AVR+AVLALR KGMVLD Sbjct 176 ---AVVLEVEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLD 232 Query 247 PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGF 306 D DTWSVGSFFTNPVVT +ERLA + DGPVP YPAPDGVKLAAGWLVE AGF Sbjct 233 EPDRDTWSVGSFFTNPVVTTAQHERLAAEV----DGPVPSYPAPDGVKLAAGWLVEHAGF 288 Query 307 GKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIG 366 GKGYP AP RLSTKHALA+TNRG AT DV+ LAR VRDGV FGI L PEP L+G Sbjct 289 GKGYP-GDDAPARLSTKHALAVTNRGHATTADVIALARTVRDGVRTTFGIELTPEPTLVG 347 Query 367 CML 369 C L Sbjct 348 CTL 350 >gi|333989111|ref|YP_004521725.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium sp. JDM601] gi|333485079|gb|AEF34471.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium sp. JDM601] Length=352 Score = 455 bits (1171), Expect = 5e-126, Method: Compositional matrix adjust. Identities = 260/363 (72%), Positives = 291/363 (81%), Gaps = 13/363 (3%) Query 7 GSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVF 66 GS FAGA +AEAVPLAPLTTLRVGP+ARRVI+C EQ+VA L LD + G RPL+ Sbjct 3 GSEFAGARVAEAVPLAPLTTLRVGPVARRVISCADTEQIVATLAALD---RDGG-RPLLL 58 Query 67 AGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSG 126 +GGSN+VIA++LTDLTVV LA+ GI I+GNL+RA+AGA++DDVV A+ GLGGLECLSG Sbjct 59 SGGSNVVIADDLTDLTVVLLASDGIEIEGNLLRAQAGAIWDDVVAAAVAAGLGGLECLSG 118 Query 127 IPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGL 186 IPGSAGATPVQNVGAYGAEV+DT+TRV LLDR TG VRW +L FGYRTSVLKH+D Sbjct 119 IPGSAGATPVQNVGAYGAEVADTLTRVLLLDRSTGIVRWTPPAELNFGYRTSVLKHSDA- 177 Query 187 AVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLD 246 VVLEVEF LDP+GRSAPLRYGEL AL A G+RADP AVR AVLALR+ KGMVLD Sbjct 178 ---GVVLEVEFELDPAGRSAPLRYGELATALGAGDGDRADPAAVRAAVLALRSAKGMVLD 234 Query 247 PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGF 306 DHDTWSVGSFFTNPVV D Y ++A A GPVPH+ AP GVKLAAGWLVERAGF Sbjct 235 AADHDTWSVGSFFTNPVVPHDSYRQIAESQA----GPVPHWDAPGGVKLAAGWLVERAGF 290 Query 307 GKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIG 366 GKGYP GA RLS+KHALALTNRGGAT DV++LAR VRDGVHD FGI L PEPVL+G Sbjct 291 GKGYPGEGAV-ARLSSKHALALTNRGGATTGDVLSLARTVRDGVHDTFGIILHPEPVLVG 349 Query 367 CML 369 C L Sbjct 350 CAL 352 >gi|126433257|ref|YP_001068948.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium sp. JLS] gi|187609730|sp|A3PU80.1|MURB_MYCSJ RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|126233057|gb|ABN96457.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium sp. JLS] Length=350 Score = 455 bits (1170), Expect = 6e-126, Method: Compositional matrix adjust. Identities = 248/363 (69%), Positives = 277/363 (77%), Gaps = 15/363 (4%) Query 7 GSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVF 66 G AGA + V LAPLTTLRVGP+ARR+IT TS EQ+VAALR A G D L+ Sbjct 3 GQELAGAEVEADVALAPLTTLRVGPVARRLITATSTEQLVAALR-----APVGRD-ALIL 56 Query 67 AGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSG 126 AGGSN+V+A+++ DLTV+R+ANS IT+ +VRAEAGA +DDVVV A+ GLGGLECLSG Sbjct 57 AGGSNVVLADDMADLTVIRVANSEITVHDGIVRAEAGANWDDVVVTALAHGLGGLECLSG 116 Query 127 IPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGL 186 IPGSAGATPVQNVGAYG+EV+DTI RVRL DR TG WV+ +D+ FGYRTSVLKH+D Sbjct 117 IPGSAGATPVQNVGAYGSEVADTIRRVRLFDRRTGRDDWVTPQDMAFGYRTSVLKHSDH- 175 Query 187 AVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLD 246 VVLEVEFALD GRSAPLRYGEL AL+ G RADP AVR+AVLALR KGMVLD Sbjct 176 ---AVVLEVEFALDVGGRSAPLRYGELARALDVEPGGRADPVAVRDAVLALRRGKGMVLD 232 Query 247 PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGF 306 D DTWSVGSFFTNPVVT +ERLA + DGPVP YPAPDGVKLAAGWLVE AGF Sbjct 233 EPDRDTWSVGSFFTNPVVTTADHERLAAEV----DGPVPSYPAPDGVKLAAGWLVEHAGF 288 Query 307 GKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIG 366 GKGYP AP RLSTKHALA+TNRG AT DV+ LAR VRDGV FGI L PEP L+G Sbjct 289 GKGYP-GDDAPARLSTKHALAVTNRGHATTADVIALARTVRDGVRTTFGIELTPEPTLVG 347 Query 367 CML 369 C L Sbjct 348 CTL 350 >gi|315442352|ref|YP_004075231.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium sp. Spyr1] gi|315260655|gb|ADT97396.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium sp. Spyr1] Length=349 Score = 453 bits (1165), Expect = 2e-125, Method: Compositional matrix adjust. Identities = 241/362 (67%), Positives = 276/362 (77%), Gaps = 16/362 (4%) Query 8 SLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFA 67 SL G +AE VPLAPLTTLRVGP+ARR++TC + +Q+V D+ G + L+ A Sbjct 4 SLLGGVPVAENVPLAPLTTLRVGPVARRLVTCVTTDQIV------DAVMAAGPE-ALILA 56 Query 68 GGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGI 127 GGSN+V+A + DLTVVRLAN+GI++DG++VRAEAGA +DDVV ++ GLGGLECLSGI Sbjct 57 GGSNVVLAGDAADLTVVRLANTGISVDGDVVRAEAGAGWDDVVAASLAHGLGGLECLSGI 116 Query 128 PGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLA 187 PGSAGATPVQNVGAYGAEV+DTI RVRLL+R TG VRWVS LRFGYRTSVLKH+ Sbjct 117 PGSAGATPVQNVGAYGAEVADTIRRVRLLERGTGSVRWVSPEFLRFGYRTSVLKHSSQW- 175 Query 188 VPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDP 247 VVLEVEF LD +GRSAP+RY EL L GER DPQ VR AVL LRARKGMVLD Sbjct 176 ---VVLEVEFGLDAAGRSAPVRYRELATELAVEQGERTDPQRVRAAVLELRARKGMVLDA 232 Query 248 TDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFG 307 DHDTWSVGSFFTNPVV++ +ER+A + VP+YPA DGVKLAAGWLVE+AGFG Sbjct 233 ADHDTWSVGSFFTNPVVSRAEFERIAATVGS----AVPNYPAEDGVKLAAGWLVEQAGFG 288 Query 308 KGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGC 367 KGYP AP RLSTKHALALTNRG AT DV+ LAR VRDGV FGI L PEPVL+GC Sbjct 289 KGYP-GDDAPVRLSTKHALALTNRGAATTADVLALARTVRDGVKAAFGIELTPEPVLVGC 347 Query 368 ML 369 L Sbjct 348 SL 349 >gi|145220696|ref|YP_001131374.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Mycobacterium gilvum PYR-GCK] gi|187609728|sp|A4T318.1|MURB_MYCGI RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|145213182|gb|ABP42586.1| UDP-N-acetylmuramate dehydrogenase [Mycobacterium gilvum PYR-GCK] Length=349 Score = 449 bits (1156), Expect = 3e-124, Method: Compositional matrix adjust. Identities = 240/362 (67%), Positives = 275/362 (76%), Gaps = 16/362 (4%) Query 8 SLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFA 67 SL G +AE VPLAPLTTLRVGP+ARR++TC + +Q+V D+ G + L+ A Sbjct 4 SLLGGVPVAENVPLAPLTTLRVGPVARRLVTCVTTDQIV------DAVMAAGPE-ALILA 56 Query 68 GGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGI 127 GGSN+V+A + DLTVVRLAN+ I++DG++VRAEAGA +DDVV ++ GLGGLECLSGI Sbjct 57 GGSNVVLAGDAADLTVVRLANTRISVDGDVVRAEAGAGWDDVVAASLAHGLGGLECLSGI 116 Query 128 PGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLA 187 PGSAGATPVQNVGAYGAEV+DTI RVRLL+R TG VRWVS LRFGYRTSVLKH+ Sbjct 117 PGSAGATPVQNVGAYGAEVADTIRRVRLLERGTGSVRWVSPEFLRFGYRTSVLKHSSQW- 175 Query 188 VPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDP 247 VVLEVEF LD +G SAP+RY EL L GER DPQ VR AVL LRARKGMVLD Sbjct 176 ---VVLEVEFGLDAAGHSAPVRYRELATELAVEQGERTDPQRVRAAVLELRARKGMVLDA 232 Query 248 TDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFG 307 DHDTWSVGSFFTNPVV++ +ER+A + VP+YPA DGVKLAAGWLVE+AGFG Sbjct 233 ADHDTWSVGSFFTNPVVSRAEFERIAATVGS----AVPNYPAEDGVKLAAGWLVEQAGFG 288 Query 308 KGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGC 367 KGYP A AP RLSTKHALALTNRG AT DV+ LAR VRDGV FGI L PEPVL+GC Sbjct 289 KGYPGAD-APARLSTKHALALTNRGTATTADVLALARTVRDGVKAAFGIELTPEPVLVGC 347 Query 368 ML 369 L Sbjct 348 SL 349 >gi|307082968|ref|ZP_07492081.1| putative UDP-N-acetylmuramate dehydrogenase [Mycobacterium tuberculosis SUMu012] gi|308367298|gb|EFP56149.1| putative UDP-N-acetylmuramate dehydrogenase [Mycobacterium tuberculosis SUMu012] Length=202 Score = 408 bits (1049), Expect = 6e-112, Method: Compositional matrix adjust. Identities = 202/202 (100%), Positives = 202/202 (100%), Gaps = 0/202 (0%) Query 168 ARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADP 227 ARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADP Sbjct 1 ARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADP 60 Query 228 QAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHY 287 QAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHY Sbjct 61 QAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHY 120 Query 288 PAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVR 347 PAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVR Sbjct 121 PAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVR 180 Query 348 DGVHDVFGITLKPEPVLIGCML 369 DGVHDVFGITLKPEPVLIGCML Sbjct 181 DGVHDVFGITLKPEPVLIGCML 202 >gi|169631144|ref|YP_001704793.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium abscessus ATCC 19977] gi|169243111|emb|CAM64139.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Mycobacterium abscessus] Length=363 Score = 377 bits (967), Expect = 2e-102, Method: Compositional matrix adjust. Identities = 209/369 (57%), Positives = 253/369 (69%), Gaps = 31/369 (8%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 GA + E LAPLTTLR+GP+A +I C S QV L LD L+ AGGSN Sbjct 15 GAVVTEGAALAPLTTLRLGPVAATLIRCESTRQVTGTLAALDGHPA------LLLAGGSN 68 Query 72 LVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSA 131 +V+A++L D+T V +A +G+T+DG+L+RAEAGA +D+VV ++ GLGGLECLSGIPG+A Sbjct 69 VVLADDLADVTAVHIAAAGVTVDGSLLRAEAGANWDEVVALSLRAGLGGLECLSGIPGTA 128 Query 132 GATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTV 191 GATPVQNVGAYG EVS + RVR+L+R TG VRW +LRFGYRTS+LK V Sbjct 129 GATPVQNVGAYGVEVSSLLRRVRVLNRETGRVRWYGPDELRFGYRTSILKGTSA----RV 184 Query 192 VLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHD 251 VLEVEF L G SAP+RY EL L G+R D AVREAVL LR RKGMVLD +D D Sbjct 185 VLEVEFGLSTDGLSAPIRYPELAKELGVAQGDRTDASAVREAVLGLRRRKGMVLDESDRD 244 Query 252 TWSVGSFFTNPVVTQD--------VYERLAGDAATRKDGP---VPHYPAPDGVKLAAGWL 300 TWSVGSFFTNPVV + V+E L GP +P Y A GVKL+AGWL Sbjct 245 TWSVGSFFTNPVVAEGDVDGVRARVHEHL---------GPGVVMPLYSAQHGVKLSAGWL 295 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 VERAGF KGYP +A R+STKHALALT+RGG + ++++TLAR VRDGV + FG+ L P Sbjct 296 VERAGFDKGYPGERSA-VRVSTKHALALTHRGGGSTDELLTLARTVRDGVLETFGVRLVP 354 Query 361 EPVLIGCML 369 EPVL+GC L Sbjct 355 EPVLVGCSL 363 >gi|226361172|ref|YP_002778950.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus opacus B4] gi|226239657|dbj|BAH50005.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus opacus B4] Length=360 Score = 352 bits (904), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 194/360 (54%), Positives = 237/360 (66%), Gaps = 10/360 (2%) Query 11 AGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGS 70 +GA ++E + L+ +TTLRVG AR V C S +V +R LD+A L+ AGGS Sbjct 10 SGAFVSENLELSGMTTLRVGGPARIVAECPSTSVLVDVVRLLDAAHIP----TLILAGGS 65 Query 71 NLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGS 130 NLV+ + D VVR+ N+ + ++ + AEAGA +D VV + + LGGLECLSGIPGS Sbjct 66 NLVVGDAGFDGVVVRVCNTTVGLEEKFITAEAGAEWDQVVAQTVAAELGGLECLSGIPGS 125 Query 131 AGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPT 190 GATPVQNVGAYG E+ + RV+LLDR TGE RWV L GYRTSVLKH+D Sbjct 126 TGATPVQNVGAYGVEIGSMLRRVQLLDRRTGEARWVEPDALGLGYRTSVLKHSDA----A 181 Query 191 VVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDH 250 +VL VE + P G S PLRY EL++AL + G+R VR AVL LR KGMVLDP DH Sbjct 182 LVLAVELTVHPDGLSEPLRYRELVSALGGSEGDRLPSAQVRGAVLDLRRGKGMVLDPDDH 241 Query 251 DTWSVGSFFTNPVVTQDVYERLAGDAATR-KDGPVPHYPAPDGVKLAAGWLVERAGFGKG 309 DTWS GSFFTNPVV+ + TR D PVP YPA G KL+AGWL+ER+GF KG Sbjct 242 DTWSAGSFFTNPVVSDGELAGVLAAIETRLGDLPVPQYPADGGTKLSAGWLIERSGFSKG 301 Query 310 YPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 YP A RLSTKH LALTNRG A +ED++ LAR VRDGV FG+ L+PEPV +GC + Sbjct 302 YPGENAV-ARLSTKHTLALTNRGAAKSEDLLALARDVRDGVQSAFGVRLEPEPVTVGCAI 360 >gi|325674045|ref|ZP_08153735.1| UDP-N-acetylmuramate dehydrogenase [Rhodococcus equi ATCC 33707] gi|325555310|gb|EGD24982.1| UDP-N-acetylmuramate dehydrogenase [Rhodococcus equi ATCC 33707] Length=367 Score = 350 bits (897), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 204/365 (56%), Positives = 241/365 (67%), Gaps = 16/365 (4%) Query 11 AGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGS 70 AGA ++E VPLA LTTLR+G A + C S +V +R LD A L+ GGS Sbjct 13 AGAQLSEQVPLASLTTLRLGGPAAVLADCASTRALVDVVRVLDDARVP----TLILGGGS 68 Query 71 NLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGS 130 NLVI+++ D VVR+A++G+ I + V A+AGAV+DDVV + + GLGGLECLSGIPGS Sbjct 69 NLVISDDGFDGVVVRVADAGVEIGDDTVLAQAGAVWDDVVAKTVAAGLGGLECLSGIPGS 128 Query 131 AGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPT 190 AGATPVQNVGAYG EV + RV+LLDR TG+VRWV +L GYRTSVLKH D Sbjct 129 AGATPVQNVGAYGVEVGALLRRVQLLDRTTGDVRWVEPSELGLGYRTSVLKHRD----DA 184 Query 191 VVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDH 250 +VL VE + P G SAPL Y EL +AL A GER VR+ VL LR KGMVLD DH Sbjct 185 LVLAVEMTVRPDGTSAPLGYRELASALGAQEGERRPTAEVRDVVLGLRRGKGMVLDGADH 244 Query 251 DTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP---VPHYPAPDG---VKLAAGWLVERA 304 DTWS GSFFTNPV+ DV DA K G +P +P P G KL+AGWL+ERA Sbjct 245 DTWSAGSFFTNPVI-PDVSLPTVLDAIRAKVGADVRIPQFPGPVGAEVTKLSAGWLIERA 303 Query 305 GFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVL 364 GFGKGYP A RLSTKH LALTNRG A D+V LAR VRDGV FG+ L+PEPV Sbjct 304 GFGKGYPGEDAR-VRLSTKHTLALTNRGHARTGDLVELARTVRDGVEREFGVRLEPEPVT 362 Query 365 IGCML 369 +GC + Sbjct 363 VGCTI 367 >gi|312141134|ref|YP_004008470.1| UDP-N-acetylenolpyruvoylglucosamine reductase murb [Rhodococcus equi 103S] gi|311890473|emb|CBH49791.1| UDP-N-acetylenolpyruvoylglucosamine reductase MurB [Rhodococcus equi 103S] Length=367 Score = 349 bits (896), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 203/365 (56%), Positives = 241/365 (67%), Gaps = 16/365 (4%) Query 11 AGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGS 70 AGA ++E VPLA LTTLR+G A + C S +V +R LD A L+ GGS Sbjct 13 AGAQLSEQVPLASLTTLRLGGPAAVLADCASTRALVDVVRVLDDARVP----TLILGGGS 68 Query 71 NLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGS 130 NLVI+++ D VVR+A++G+ + + V A+AGAV+DDVV + + GLGGLECLSGIPGS Sbjct 69 NLVISDDGFDGVVVRVADAGVELGDDTVLAQAGAVWDDVVAKTVAAGLGGLECLSGIPGS 128 Query 131 AGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPT 190 AGATPVQNVGAYG EV + RV+LLDR +G+VRWV DL GYRTSVLKH D Sbjct 129 AGATPVQNVGAYGVEVGTLLRRVQLLDRTSGDVRWVEPSDLGLGYRTSVLKHRD----DA 184 Query 191 VVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDH 250 +VL VE + P G SAPL Y EL +AL A GER VR+ VL LR KGMVLD DH Sbjct 185 LVLAVEMTVRPDGASAPLGYRELASALGAQEGERRPTAEVRDVVLGLRRGKGMVLDAADH 244 Query 251 DTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP---VPHYPAPDG---VKLAAGWLVERA 304 DTWS GSFFTNPV+ DV DA K G +P +P P G KL+AGWL+ERA Sbjct 245 DTWSAGSFFTNPVI-PDVSLPTVLDAIRAKVGADVRIPQFPGPVGAEVTKLSAGWLIERA 303 Query 305 GFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVL 364 GFGKGYP A RLSTKH LALTNRG A D+V LAR VRDGV FG+ L+PEPV Sbjct 304 GFGKGYPGEDAR-VRLSTKHTLALTNRGHARTGDLVELARTVRDGVEREFGVRLEPEPVT 362 Query 365 IGCML 369 +GC + Sbjct 363 VGCTI 367 >gi|54027171|ref|YP_121413.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Nocardia farcinica IFM 10152] gi|81373076|sp|Q5YP42.1|MURB_NOCFA RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|54018679|dbj|BAD60049.1| putative UDP-N-acetylenolpyruvoylglucosamine reductase [Nocardia farcinica IFM 10152] Length=382 Score = 348 bits (894), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 220/359 (62%), Positives = 253/359 (71%), Gaps = 11/359 (3%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 GA + EAV LA LTTLRVG A + C + E +VA +R LD+A L+ AGGSN Sbjct 34 GATVREAVRLAELTTLRVGGPAV-LAECGTTEALVATVRALDAAGVP----VLLLAGGSN 88 Query 72 LVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSA 131 L++ ++ D VVR+A SG+ + + V AEAGA +D VV + GLGGLECLSGIPGSA Sbjct 89 LLVGDDGFDGVVVRVATSGVELGADGVLAEAGADWDAVVAATVAAGLGGLECLSGIPGSA 148 Query 132 GATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTV 191 GATPVQNVGAYG EV++ + RVRLLDR TGE+RW +L FGYRTSVLKH+D V Sbjct 149 GATPVQNVGAYGVEVAELLRRVRLLDRATGEIRWAGPGELGFGYRTSVLKHSDA----AV 204 Query 192 VLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHD 251 VL VEFAL P G SAPLRY EL AAL A GE AVREAVL LRA KGMVLDP DHD Sbjct 205 VLAVEFALRPDGSSAPLRYRELAAALAADEGESRPAAAVREAVLRLRASKGMVLDPADHD 264 Query 252 TWSVGSFFTNPVVTQDVYERL-AGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGY 310 TWS GSFFTNPVV D E++ A A + +P YPA DGVKL+AGWL+ERAGFGKG+ Sbjct 265 TWSAGSFFTNPVVPADRIEQVRAAIHAHVGEVTIPTYPAADGVKLSAGWLIERAGFGKGW 324 Query 311 PDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 P A AP RLSTKH LALTNRG A A DVV LAR VRDGV + FGI L+PEPV +G L Sbjct 325 PGA-EAPARLSTKHTLALTNRGTARAADVVALARTVRDGVAERFGIRLEPEPVTVGVRL 382 >gi|229490523|ref|ZP_04384361.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus erythropolis SK121] gi|229322343|gb|EEN88126.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus erythropolis SK121] Length=347 Score = 348 bits (893), Expect = 9e-94, Method: Compositional matrix adjust. Identities = 195/356 (55%), Positives = 234/356 (66%), Gaps = 10/356 (2%) Query 15 IAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVI 74 ++E V L+ LTTLR+G AR + C + + ++ + LD L+ AGGSNLVI Sbjct 1 MSENVDLSGLTTLRIGGPARLLAECPTTQSLIDVVTLLDREQIP----TLILAGGSNLVI 56 Query 75 AENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGAT 134 +++ D VVR+AN+ +++D + V AEAGAV+D+VV +++ LGGLECLSGIPGS GAT Sbjct 57 SDSGFDGVVVRVANTTVSLDTDRVVAEAGAVWDEVVGQSVAAELGGLECLSGIPGSTGAT 116 Query 135 PVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLE 194 PVQNVGAYG EV + RV+LLDR GEV WV L GYR+SVLKH+D +VL Sbjct 117 PVQNVGAYGVEVGSRLRRVQLLDRRNGEVSWVEPSKLDLGYRSSVLKHSDA----ALVLA 172 Query 195 VEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWS 254 VEF G SAPL Y EL AL A G R VREAVL LR K MVLDP DHDTWS Sbjct 173 VEFDASTDGLSAPLAYRELFTALGAEEGARLPASQVREAVLGLRTGKAMVLDPYDHDTWS 232 Query 255 VGSFFTNPVVTQDVYER-LAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDA 313 GSFFTNPVV D L A D VP +P G KL+AGWL+ERAGF KGYP Sbjct 233 AGSFFTNPVVPDDKLPAVLEAIAEQLGDVTVPQFPGSGGTKLSAGWLIERAGFSKGYPGE 292 Query 314 GAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 AP RLSTKH LALTNRG AT+ DVV+LAR VRDGV FG+ L+PEPV +GC + Sbjct 293 D-APARLSTKHTLALTNRGSATSADVVSLARTVRDGVEAAFGVHLEPEPVTVGCTV 347 >gi|226305090|ref|YP_002765048.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus erythropolis PR4] gi|226184205|dbj|BAH32309.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus erythropolis PR4] Length=347 Score = 348 bits (892), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 196/357 (55%), Positives = 237/357 (67%), Gaps = 12/357 (3%) Query 15 IAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVI 74 ++E V L+ LTTLR+G AR + C + + ++ + LD L+ AGGSNLVI Sbjct 1 MSENVDLSGLTTLRIGGPARLLAECPTTQSLIDVVTLLDREQIP----TLILAGGSNLVI 56 Query 75 AENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGAT 134 ++ D VVR+AN+ +++D + V AEAGAV+D+VV +++ LGGLECLSGIPGS GAT Sbjct 57 SDAGFDGVVVRVANTTVSLDTDRVIAEAGAVWDEVVGQSVAAELGGLECLSGIPGSTGAT 116 Query 135 PVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLE 194 PVQNVGAYG EV + +V+LLDR +GEV WV L GYR+SVLKH+D VVL Sbjct 117 PVQNVGAYGVEVGSRLRQVQLLDRRSGEVSWVEPSKLELGYRSSVLKHSDA----AVVLA 172 Query 195 VEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWS 254 VEF G SAPL Y EL AL A GER VREAVL LR K MVLDP DHDTWS Sbjct 173 VEFDASTDGLSAPLAYRELFTALGAEEGERLPASQVREAVLGLRTGKAMVLDPYDHDTWS 232 Query 255 VGSFFTNPVVTQDVYERLAGDAATRK--DGPVPHYPAPDGVKLAAGWLVERAGFGKGYPD 312 GSFFTNPVV D + G A T + D VP +P G KL+AGWL+ERAGF KGYP Sbjct 233 AGSFFTNPVVPDDKLPAVLG-AITEQLGDVTVPQFPGSGGTKLSAGWLIERAGFSKGYPG 291 Query 313 AGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 AP RLSTKH LALTNRG AT+ DVV+LAR VRDGV FG+ L+PEPV +G + Sbjct 292 ED-APARLSTKHTLALTNRGSATSADVVSLARTVRDGVEAAFGVHLEPEPVTVGFTI 347 >gi|302523810|ref|ZP_07276152.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Streptomyces sp. AA4] gi|302432705|gb|EFL04521.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Streptomyces sp. AA4] Length=351 Score = 345 bits (886), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 189/349 (55%), Positives = 230/349 (66%), Gaps = 9/349 (2%) Query 21 LAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTD 80 LA TTLR+G RR IT T+A+++VAA+R D + + L+ GGSNLV+ + D Sbjct 12 LAEYTTLRLGGPVRRSITATTADELVAAVRAADESGEP----VLLLGGGSNLVVGDAGFD 67 Query 81 LTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVG 140 T+VR+AN+G T DG++V AG +D V ++ GLGGLECLSGIPGS GATP+QNVG Sbjct 68 GTLVRIANTGWTRDGDVVEVAAGQEWDAFVAALVDSGLGGLECLSGIPGSVGATPIQNVG 127 Query 141 AYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFALD 200 AYG EV+++I V L DR EVR V A +L F YRTSVLK D VVL V F +D Sbjct 128 AYGGEVAESIVSVELYDRAAKEVRTVKADELGFAYRTSVLKGTD----RGVVLSVRFRID 183 Query 201 PSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFT 260 PSG+SAP+RY EL L + REAVL LR KGMVLDP DHDTWS GSFFT Sbjct 184 PSGQSAPIRYAELARTLGVEIDAKVPAARAREAVLGLRRGKGMVLDPADHDTWSAGSFFT 243 Query 261 NPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRL 320 NP+V ++ + A +G +P YPA GVKL+A WL+ERAGFGKGYP G L Sbjct 244 NPIVPEEEAPAVLARIAESTEGKIPQYPASGGVKLSAAWLIERAGFGKGYPGPGGR-VSL 302 Query 321 STKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 S KH LALTNRGGA+ ED++ LAR VRDGV FG+ L PEP+LI C L Sbjct 303 SAKHTLALTNRGGASTEDLLALAREVRDGVEARFGVRLYPEPLLINCSL 351 >gi|111019079|ref|YP_702051.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Rhodococcus jostii RHA1] gi|110818609|gb|ABG93893.1| UDP-N-acetylmuramate dehydrogenase [Rhodococcus jostii RHA1] Length=338 Score = 341 bits (875), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 190/347 (55%), Positives = 229/347 (66%), Gaps = 10/347 (2%) Query 24 LTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTV 83 +TTLRVG AR V C + + +V +R LD+A L+ AGGSNLV+ ++ D V Sbjct 1 MTTLRVGGPARIVAECPTTQVLVDVVRLLDAAHIP----TLILAGGSNLVVGDDGFDGVV 56 Query 84 VRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYG 143 VR+ N+ + ++ V AEAGA +D VV + + LGGLECLSGIPGS GATPVQNVGAYG Sbjct 57 VRVCNTTVGLEEGFVTAEAGAEWDRVVAQTVAAELGGLECLSGIPGSTGATPVQNVGAYG 116 Query 144 AEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSG 203 EV + RV LLDR TGE RWV L GYRTSVLKH+D +VL VE + P G Sbjct 117 VEVGSMLRRVHLLDRRTGEARWVEPDALGLGYRTSVLKHSDA----ALVLAVELTVHPDG 172 Query 204 RSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPV 263 PLRY EL++AL++ G+R VR+AVL LR KGMVLDP DHDTWS GSFFTNPV Sbjct 173 LGEPLRYRELVSALDSAEGDRLPSTQVRDAVLDLRRGKGMVLDPDDHDTWSAGSFFTNPV 232 Query 264 VTQ-DVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLST 322 V ++ LA D VP YPA G KL+AGWL+ERAGF KGYP A RLST Sbjct 233 VPDGELVNVLAAIETRLGDVAVPRYPADGGTKLSAGWLIERAGFSKGYPGENAV-ARLST 291 Query 323 KHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 KH LALTNRG A +ED++ LAR VRDGV FG+ L+PEPV +GC + Sbjct 292 KHTLALTNRGAAKSEDLLALARDVRDGVQSAFGVRLEPEPVTVGCAI 338 >gi|333918293|ref|YP_004491874.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Amycolicicoccus subflavus DQS3-9A1] gi|333480514|gb|AEF39074.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Amycolicicoccus subflavus DQS3-9A1] Length=369 Score = 329 bits (844), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 188/361 (53%), Positives = 233/361 (65%), Gaps = 12/361 (3%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 GA ++ PLA TTLR+G A ++TCT+ + + +R LD L+ AGGSN Sbjct 18 GAAVSFGTPLAAHTTLRLGGPAAAIVTCTTTDMLAGVVRRLDQEQVP----VLILAGGSN 73 Query 72 LVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSA 131 LVIA+ D VVR+A + +IDG +V AEAG +D VV ++ GLGGLECLSGIPGS Sbjct 74 LVIADEGVDAVVVRVAATSYSIDGAVVHAEAGTNWDTVVAASVVAGLGGLECLSGIPGST 133 Query 132 GATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTV 191 GATPVQNVGAYG E+S + RV+LL+R +G V W DL YR S+LK+ D V Sbjct 134 GATPVQNVGAYGVEISSVLRRVKLLERASGNVHWADPADLHLSYRHSILKNTD----TAV 189 Query 192 VLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHD 251 VL VE L G SAP+RYGEL L A G+R VR+AVL LR KGMVL+ DHD Sbjct 190 VLSVEMGLLDDGLSAPVRYGELARNLGAAEGDRVAAAQVRDAVLKLRGSKGMVLNSQDHD 249 Query 252 TWSVGSFFTNPVVTQDVYERLAGDAATR--KDGPVPHYPAPD-GVKLAAGWLVERAGFGK 308 TWS GSFFTNP+V+++ R+ R ++ VP + + D GVKL+AGWL+ERAGF + Sbjct 250 TWSAGSFFTNPIVSREDLPRVLAAIRERLGEETAVPQFASADGGVKLSAGWLIERAGFSR 309 Query 309 GYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCM 368 G+P A RLSTKH LALTNRG AT D+V LAR VRDGV D FG+ L PEPV +G Sbjct 310 GFPGED-ARARLSTKHTLALTNRGDATTADLVGLARTVRDGVRDAFGVNLHPEPVFVGAQ 368 Query 369 L 369 L Sbjct 369 L 369 >gi|227541623|ref|ZP_03971672.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glucuronolyticum ATCC 51866] gi|227182591|gb|EEI63563.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glucuronolyticum ATCC 51866] Length=347 Score = 328 bits (841), Expect = 8e-88, Method: Compositional matrix adjust. Identities = 194/355 (55%), Positives = 228/355 (65%), Gaps = 26/355 (7%) Query 19 VPLAPLTTLRVGPIARRVITCTSAEQVVAALR-HLDSAAKTGADRPLVFAGGSNLVIAEN 77 V A LTTL VG R CT+ VV A++ H D+ L+ GGSNL++A+ Sbjct 15 VTFADLTTLHVGGSPRAAFRCTTQNAVVEAVQAHPDA---------LIVGGGSNLLVADG 65 Query 78 LTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQ 137 DLT V + +TIDG+ VRAEAGA +DDVV + GLGG+ECLSGIPGSAGATPVQ Sbjct 66 PLDLTAVIIGMDRVTIDGSTVRAEAGARWDDVVATTVAAGLGGIECLSGIPGSAGATPVQ 125 Query 138 NVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEF 197 NVGAYGAE++D + RV+L DR +GEV WV A L YR S LK G A VVLE+E Sbjct 126 NVGAYGAEIADVLRRVKLFDRRSGEVSWVDAESLDLAYRYSNLKFT-GRA---VVLEIEL 181 Query 198 ALDPSGRSAPLRYGELIAALNATS-GERADPQAVREAVLALRARKGMVLDPTDHDTWSVG 256 L G S PLR+G+L L A+ GER VREAVL LR KGMV DP DHDTWS G Sbjct 182 ELFADGLSHPLRFGQLAKKLGASHGGERRPAAEVREAVLELRRSKGMVYDPADHDTWSAG 241 Query 257 SFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDG-VKLAAGWLVER-AGFGKGYPDAG 314 SFFTNP+VT V +RL DA P YPA DG VKL+A WL+++ AGF KG+P Sbjct 242 SFFTNPIVTSAVADRLPDDA--------PRYPADDGQVKLSAAWLIDKVAGFNKGFPGED 293 Query 315 AAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 A RLSTKH LALTNRG ATA D+V LAR +RDGV GI L PEPV +G + Sbjct 294 AV-ARLSTKHTLALTNRGNATAADIVDLARTIRDGVFSKTGIELHPEPVWVGLSM 347 >gi|134103404|ref|YP_001109065.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Saccharopolyspora erythraea NRRL 2338] gi|187609748|sp|A4FQ15.1|MURB_SACEN RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|133916027|emb|CAM06140.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Saccharopolyspora erythraea NRRL 2338] Length=366 Score = 328 bits (840), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 199/359 (56%), Positives = 227/359 (64%), Gaps = 21/359 (5%) Query 21 LAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTD 80 LA TTLR+G A + AE + A+R D+A R LV GGSNLV+A+ D Sbjct 19 LAAYTTLRLGGPAAGFVVAEDAETLADAVREADAAGS----RLLVLGGGSNLVVADEGFD 74 Query 81 LTVVRLANSGITIDG---NLVR--AEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATP 135 VVR+A G+ D LV+ AEAG +D VV + QGLGGLECLSGIPG GATP Sbjct 75 GHVVRIATRGLRFDSVGDGLVQLTAEAGEDWDAVVAETVRQGLGGLECLSGIPGLTGATP 134 Query 136 VQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEV 195 VQNVGAYG EVS+ + V LLDR TG VR V A DL YR SVLKH+D VVL V Sbjct 135 VQNVGAYGVEVSELLLSVDLLDRRTGNVRTVRAEDLGLVYRGSVLKHSD----QAVVLRV 190 Query 196 EFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSV 255 F L GRSAP+RY EL L+A G R D REAVLALR KGMVLDP DHDTWS Sbjct 191 RFLLRDGGRSAPVRYAELARTLDAEPGSRVDVAEAREAVLALRRGKGMVLDPADHDTWSA 250 Query 256 GSFFTNPVVT----QDVYERLAGDAATRKDGPVPHYPAPDG-VKLAAGWLVERAGFGKGY 310 GSFFTNP+V V R+ A D VP YPA DG KL+A WL+ERAGFGKG+ Sbjct 251 GSFFTNPIVEAADLSAVLSRIG--AKVGPDQRVPQYPASDGRTKLSAAWLIERAGFGKGH 308 Query 311 PDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 P G RLSTKH LALTNRG AT D+++LAR VRDGV FG++L PEPVL+ C L Sbjct 309 PGPGGR-ARLSTKHTLALTNRGEATTADLLSLAREVRDGVLAQFGVSLAPEPVLVDCAL 366 >gi|291006056|ref|ZP_06564029.1| UDP-N-acetylmuramate dehydrogenase [Saccharopolyspora erythraea NRRL 2338] Length=369 Score = 328 bits (840), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 199/359 (56%), Positives = 227/359 (64%), Gaps = 21/359 (5%) Query 21 LAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTD 80 LA TTLR+G A + AE + A+R D+A R LV GGSNLV+A+ D Sbjct 22 LAAYTTLRLGGPAAGFVVAEDAETLADAVREADAAGS----RLLVLGGGSNLVVADEGFD 77 Query 81 LTVVRLANSGITIDG---NLVR--AEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATP 135 VVR+A G+ D LV+ AEAG +D VV + QGLGGLECLSGIPG GATP Sbjct 78 GHVVRIATRGLRFDSVGDGLVQLTAEAGEDWDAVVAETVRQGLGGLECLSGIPGLTGATP 137 Query 136 VQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEV 195 VQNVGAYG EVS+ + V LLDR TG VR V A DL YR SVLKH+D VVL V Sbjct 138 VQNVGAYGVEVSELLLSVDLLDRRTGNVRTVRAEDLGLVYRGSVLKHSD----QAVVLRV 193 Query 196 EFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSV 255 F L GRSAP+RY EL L+A G R D REAVLALR KGMVLDP DHDTWS Sbjct 194 RFLLRDGGRSAPVRYAELARTLDAEPGSRVDVAEAREAVLALRRGKGMVLDPADHDTWSA 253 Query 256 GSFFTNPVVT----QDVYERLAGDAATRKDGPVPHYPAPDG-VKLAAGWLVERAGFGKGY 310 GSFFTNP+V V R+ A D VP YPA DG KL+A WL+ERAGFGKG+ Sbjct 254 GSFFTNPIVEAADLSAVLSRIG--AKVGPDQRVPQYPASDGRTKLSAAWLIERAGFGKGH 311 Query 311 PDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 P G RLSTKH LALTNRG AT D+++LAR VRDGV FG++L PEPVL+ C L Sbjct 312 PGPGGR-ARLSTKHTLALTNRGEATTADLLSLAREVRDGVLAQFGVSLAPEPVLVDCAL 369 >gi|319949960|ref|ZP_08023951.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Dietzia cinnamea P4] gi|319436375|gb|EFV91504.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Dietzia cinnamea P4] Length=352 Score = 327 bits (838), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 188/349 (54%), Positives = 228/349 (66%), Gaps = 21/349 (6%) Query 26 TLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRP-LVFAGGSNLVIAENLTDLTVV 84 TLR+G R ++ C + E VVAA+R LD+A + P LV GGSNLV+A DL VV Sbjct 1 TLRIGGRPRALLECATPEAVVAAVRALDAA-----EVPVLVLGGGSNLVVAGGDLDLVVV 55 Query 85 RLAN------SGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQN 138 + N +G D +VRA AG ++D+V + +G GGLECLSGIPGS GATPVQN Sbjct 56 AVRNREVEYLAGAGEDRLVVRAGAGLTWEDLVADTVGRGYGGLECLSGIPGSVGATPVQN 115 Query 139 VGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFA 198 VGAYG EV+ + RVR DR TG WV+ L YRTSVLK+ D VVLEVEF Sbjct 116 VGAYGVEVAQILHRVRWYDRATGVDEWVTPEALGLAYRTSVLKNTD----RAVVLEVEFR 171 Query 199 LDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSF 258 LDP+GRS P+RY EL L T GER DP VR VL LR KGMVLD D DTWS GSF Sbjct 172 LDPAGRSEPIRYAELAGRLGVTPGERTDPAVVRRTVLELRRGKGMVLDDDDEDTWSAGSF 231 Query 259 FTNPVVTQD----VYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAG 314 FTNPV+ +D V R+A + +P + AP GVKL+AGWL+ERAGFGKG+P + Sbjct 232 FTNPVIREDELPTVRSRVAARLGSAPAEQMPAFSAPGGVKLSAGWLIERAGFGKGHPSS- 290 Query 315 AAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPV 363 ++P RLSTKH LALTNRG AT++D++ LAR VRDGV + FG+ L P V Sbjct 291 SSPARLSTKHTLALTNRGAATSDDIIALAREVRDGVREAFGVELHPSRV 339 >gi|343925757|ref|ZP_08765272.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Gordonia alkanivorans NBRC 16433] gi|343764108|dbj|GAA12198.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Gordonia alkanivorans NBRC 16433] Length=373 Score = 327 bits (837), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 191/376 (51%), Positives = 233/376 (62%), Gaps = 35/376 (9%) Query 18 AVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAEN 77 + PLA LTTLR+G AR ++ C +V ++ LD ++ LV GGSNLVI + Sbjct 9 SAPLAELTTLRLGGPAREIVRCPDTRSIVETIQELDERSEP----VLVIGGGSNLVIGDA 64 Query 78 LTDLTVVRLANSGITIDGNL------VRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSA 131 D T V LA+S I V A+AG +DD+V +E G GGLECLSGIPG+A Sbjct 65 GFDGTAVVLASSRIEFGSGRESGRPHVVADAGVGWDDLVAATVEAGFGGLECLSGIPGAA 124 Query 132 GATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTV 191 GATPVQNVGAYG EV+D + V++LDR +G +RWVS +L GYRTS LKH + V Sbjct 125 GATPVQNVGAYGVEVADILRSVQVLDRRSGTLRWVSPAELGLGYRTSNLKHRNDF----V 180 Query 192 VLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHD 251 V+ V F L+ S P+RY EL + G+R D REAVL LR KGMVLDP D D Sbjct 181 VVAVSFWLNDDRASQPIRYRELATTVGVEPGDRVDAVTAREAVLGLRRGKGMVLDPDDFD 240 Query 252 TWSVGSFFTNPVVTQD----VYERLAGDAATRKDGPVPHYP--------------APDGV 293 TWS GSFFTNP+V + V ER+A A D +P YP AP + Sbjct 241 TWSAGSFFTNPIVDGEDAPAVLERIA--ARVGDDVAIPSYPAGPQPNTGDSPNADAPTAI 298 Query 294 KLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDV 353 KL+AGWL+ERAGFG+GYP A AP RLSTKH LALTNRG AT E ++TLAR VRDGV D Sbjct 299 KLSAGWLIERAGFGRGYPSAD-APVRLSTKHTLALTNRGAATTEQLLTLAREVRDGVLDT 357 Query 354 FGITLKPEPVLIGCML 369 FG+TL+PEPV + C L Sbjct 358 FGVTLRPEPVFVNCAL 373 >gi|227487207|ref|ZP_03917523.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glucuronolyticum ATCC 51867] gi|227092865|gb|EEI28177.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glucuronolyticum ATCC 51867] Length=347 Score = 326 bits (836), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 193/355 (55%), Positives = 227/355 (64%), Gaps = 26/355 (7%) Query 19 VPLAPLTTLRVGPIARRVITCTSAEQVVAALR-HLDSAAKTGADRPLVFAGGSNLVIAEN 77 V A LTTL VG R CT+ VV A++ H D+ L+ GGSNL++A+ Sbjct 15 VTFADLTTLHVGGSPRAAFRCTTQNAVVEAVKAHPDA---------LIVGGGSNLLVADG 65 Query 78 LTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQ 137 DLT V + +TIDG+ VRAEAGA +DDVV + GLGG+ECLSGIPGSAGATPVQ Sbjct 66 PLDLTAVIMGMDRVTIDGSTVRAEAGARWDDVVATTVAAGLGGIECLSGIPGSAGATPVQ 125 Query 138 NVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEF 197 NVGAYGAE++D + RV+L DR +GEV WV A L YR S LK G A VVLE+E Sbjct 126 NVGAYGAEIADVLRRVKLFDRRSGEVSWVDAESLDLAYRYSNLKFT-GRA---VVLEIEL 181 Query 198 ALDPSGRSAPLRYGELIAALNATS-GERADPQAVREAVLALRARKGMVLDPTDHDTWSVG 256 L G S PLR+G+L L A+ GER VREAVL LR KGMV DP DHDTWS G Sbjct 182 ELFADGLSHPLRFGQLAKKLGASHGGERRPAAEVREAVLELRRSKGMVYDPADHDTWSAG 241 Query 257 SFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDG-VKLAAGWLVER-AGFGKGYPDAG 314 SFFTNP+VT V + L DA P YPA DG VKL+A WL+++ AGF KG+P Sbjct 242 SFFTNPIVTSAVADGLPDDA--------PRYPADDGQVKLSAAWLIDKVAGFNKGFPGED 293 Query 315 AAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 A RLSTKH LALTNRG ATA D+V LAR +RDGV GI L PEPV +G + Sbjct 294 AV-ARLSTKHTLALTNRGNATAADIVDLARTIRDGVFSKTGIELHPEPVWVGLSM 347 >gi|300782383|ref|YP_003762674.1| UDP-N-acetylmuramate dehydrogenase [Amycolatopsis mediterranei U32] gi|299791897|gb|ADJ42272.1| UDP-N-acetylmuramate dehydrogenase [Amycolatopsis mediterranei U32] gi|340523750|gb|AEK38955.1| UDP-N-acetylmuramate dehydrogenase [Amycolatopsis mediterranei S699] Length=351 Score = 325 bits (834), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 185/353 (53%), Positives = 226/353 (65%), Gaps = 17/353 (4%) Query 21 LAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTD 80 LA TTLR+G AR+ ++ ++E ++AA+R D+A + L+ GGSNLV+ + D Sbjct 12 LAAYTTLRLGGPARQFVSAVTSEDLIAAVREADAAGEP----VLLLGGGSNLVVGDAGFD 67 Query 81 LTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVG 140 T+V +AN+G DG+ V +AG +D V +E GLGGLECLSGIPGS GATP+QNVG Sbjct 68 GTLVEVANTGWRRDGDRVEVQAGQNWDAFVAALVEAGLGGLECLSGIPGSVGATPIQNVG 127 Query 141 AYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFALD 200 AYG EV+++I V L DR T EVR + A +L F YRTSVLK D VVL V F + Sbjct 128 AYGCEVAESIVSVELYDRGTREVRTLKAGELGFAYRTSVLKGTD----TGVVLSVRFEVR 183 Query 201 PSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFT 260 G SAP+RY EL L G R REAVL LR KGMVLDP DHDTWS GSFFT Sbjct 184 EDGLSAPIRYAELARTLGVEIGARVPAAEAREAVLELRRGKGMVLDPDDHDTWSAGSFFT 243 Query 261 NPVV----TQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAA 316 NP+V + V ER+ P YPA GVKL+A WL+ERAGFGKGYP G Sbjct 244 NPIVPSAEAEAVLERITAVVGAE----TPQYPADGGVKLSAAWLIERAGFGKGYPGPGNR 299 Query 317 PCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 LSTKH LALTNRG AT ED++ LAR VRDGV + FG+ L PEP+LI C++ Sbjct 300 -VSLSTKHTLALTNRGDATTEDLLALAREVRDGVFERFGVRLHPEPLLINCVI 351 >gi|296141320|ref|YP_003648563.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Tsukamurella paurometabola DSM 20162] gi|296029454|gb|ADG80224.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Tsukamurella paurometabola DSM 20162] Length=351 Score = 323 bits (828), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 195/356 (55%), Positives = 231/356 (65%), Gaps = 18/356 (5%) Query 18 AVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAEN 77 ++ L+ LTTLR+G AR + CT+ +V AA+ + + LV GGSNLVIA+ Sbjct 2 SILLSDLTTLRLGGPARGYVRCTTGAEVAAAV----ARCDAAGEPVLVVGGGSNLVIADA 57 Query 78 LTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQ 137 + TVV L G+ IDG V A AG ++D+VV + GLGGLECLSGIPGSAGATPVQ Sbjct 58 GFEGTVVHLTGRGVAIDGTRVTAFAGVLWDEVVAATVGAGLGGLECLSGIPGSAGATPVQ 117 Query 138 NVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEF 197 NVGAYG EVS + V L R TGE WV DLR YRTS LK +D +VL V F Sbjct 118 NVGAYGVEVSAWLDAVELYHRATGETAWVPPADLRLAYRTSRLKASDS----DIVLSVRF 173 Query 198 ALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGS 257 AL G SAP+RYGEL AL G DP A RE VLALR KGMVLD TDHDTWSVGS Sbjct 174 ALT-DGASAPIRYGELARALGVQPGATVDPHAAREEVLALRRGKGMVLDETDHDTWSVGS 232 Query 258 FFTNPVV----TQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDA 313 FFTNPV+ V +R+ +AAT + P YPAPDGVKL+AGWL+ERAGFGKGY Sbjct 233 FFTNPVLPAVDAPRVIDRI--EAATGQT--PPQYPAPDGVKLSAGWLIERAGFGKGY-SG 287 Query 314 GAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 G + LSTKH LALTNRG + ++++LA VRDGV FG+ L PEPVL+G L Sbjct 288 GRSGVSLSTKHTLALTNRGAGSTAELLSLAAEVRDGVFARFGVELHPEPVLVGSDL 343 >gi|326384040|ref|ZP_08205723.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Gordonia neofelifaecis NRRL B-59395] gi|326197200|gb|EGD54391.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Gordonia neofelifaecis NRRL B-59395] Length=359 Score = 322 bits (824), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 188/355 (53%), Positives = 219/355 (62%), Gaps = 15/355 (4%) Query 21 LAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTD 80 LA LTTLR+G AR V+ C + +V + LDSA + L+ GGSNLVI ++ D Sbjct 12 LAELTTLRLGGPARSVVRCDDTDSLVTTVGELDSAGEP----VLLIGGGSNLVIGDDGFD 67 Query 81 LTVVRLANSGITIDGN----LVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPV 136 T V +A SGI V AEAG +D +V + G GGLECLSGIPG+AG TPV Sbjct 68 GTAVLIATSGIEYGDEAGRPYVTAEAGNDWDALVADTVAAGFGGLECLSGIPGAAGTTPV 127 Query 137 QNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVE 196 QNVGAYG EV+D + VRL DR TG V WVS L YRTSVLK D VVL V Sbjct 128 QNVGAYGVEVADVLRSVRLFDRATGSVEWVSPESLGMAYRTSVLKGRD----DHVVLAVS 183 Query 197 FALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVG 256 F L+P G SAP+ Y EL L G + VR VLALRA KGMVLD DHDTWS G Sbjct 184 FWLNPDGVSAPIAYRELARVLGVDEGGTTEAAQVRAQVLALRAGKGMVLDDGDHDTWSAG 243 Query 257 SFFTNPVVTQDVYERLAGDAATR--KDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAG 314 SFFTNP+V + + + A R D +P YPA GVKL+AGWL+ERAGF KG+P Sbjct 244 SFFTNPIVAEAEADAVLARIADRLGDDVSIPRYPADAGVKLSAGWLIERAGFTKGFP-GD 302 Query 315 AAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML 369 AP RLSTKH LALTNRG AT D++ LA VRDGV D FG+ L PEPV + C L Sbjct 303 DAPVRLSTKHTLALTNRGSATTADLLALAARVRDGVRDAFGVDLHPEPVFVNCRL 357 >gi|311740992|ref|ZP_07714817.1| UDP-N-acetylmuramate dehydrogenase [Corynebacterium pseudogenitalium ATCC 33035] gi|311303794|gb|EFQ79872.1| UDP-N-acetylmuramate dehydrogenase [Corynebacterium pseudogenitalium ATCC 33035] Length=368 Score = 319 bits (818), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 190/369 (52%), Positives = 232/369 (63%), Gaps = 28/369 (7%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 G + A A LTTLRVG + + C+ E VA +R LD A + +V GGSN Sbjct 15 GVELDPAATFADLTTLRVGGKPQAALRCSQPEAAVAVVRALDHAEV----KFIVVGGGSN 70 Query 72 LVIAENLTDLTVVRLANSGITIDGN--LVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 L++A+ DL V L +++D +VRA+AGAV+DDVV R+++ GLGG+ECLSGIPG Sbjct 71 LLVADGAVDLVAVVLDFDEVSMDTETGVVRAQAGAVWDDVVARSVQLGLGGIECLSGIPG 130 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 + GA PVQNVGAYGAE+S+ +TRVRL +R T WV A DL YR S LK G A Sbjct 131 TVGAVPVQNVGAYGAEISEVLTRVRLYNRRTDTDEWVPASDLELAYRYSNLKFT-GRA-- 187 Query 190 TVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTD 249 VVLEVE LD G S PLR+G+ L GER VRE VL LR KGMVLDPTD Sbjct 188 -VVLEVELQLDNEGLSRPLRFGQ----LTQNPGERRPVAEVREEVLKLRRSKGMVLDPTD 242 Query 250 HDTWSVGSFFTNPVVTQDVYERLA-------GDAATRKDGPVPHYPAPDG--VKLAAGWL 300 HDTWS GSFFTNPVV + + + GDA +P +P+ + KL+A WL Sbjct 243 HDTWSAGSFFTNPVVDSALADAVQAKVRASLGDATADS---MPRHPSAETGREKLSAAWL 299 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 ++RAGF KGYP +G A LSTKH LALTNRG ATA D+V LAR +RDGVH+ FG+ L P Sbjct 300 IDRAGFAKGYPGSGRAT--LSTKHTLALTNRGEATAADIVDLARTIRDGVHETFGVELVP 357 Query 361 EPVLIGCML 369 EPV IG L Sbjct 358 EPVWIGLSL 366 >gi|161485999|ref|NP_737027.2| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium efficiens YS-314] gi|259508544|ref|ZP_05751444.1| UDP-N-acetylenolpyruvoylglucosamine reductase 2 (UDP-N-acetylmuramate dehydrogenase 2) [Corynebacterium efficiens YS-314] gi|259163894|gb|EEW48448.1| UDP-N-acetylenolpyruvoylglucosamine reductase 2 (UDP-N-acetylmuramate dehydrogenase 2) [Corynebacterium efficiens YS-314] Length=377 Score = 315 bits (807), Expect = 8e-84, Method: Compositional matrix adjust. Identities = 189/371 (51%), Positives = 235/371 (64%), Gaps = 22/371 (5%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 GA + V A LTTL +G R + C + + V +R LD A+ LV GGSN Sbjct 15 GAELDPDVTFADLTTLHIGGKPRLAVRCATTDAVAQVVRMLDDASVP----LLVVGGGSN 70 Query 72 LVIAENLTDLTVVRLANSGITID--GNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 LV+A+ D+ V + +T++ +V AEAGA +DDVV +++ GLGG+ECLSGIPG Sbjct 71 LVVADGELDVVAVIIEADDVTLNLANGVVVAEAGAEWDDVVSLSVDAGLGGIECLSGIPG 130 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 SAGATPVQNVGAYG E+SD +TRV+LLDR TGEV WV A L YR S LK + Sbjct 131 SAGATPVQNVGAYGVEISDVLTRVQLLDRGTGEVSWVDASSLELAYRYSNLKFTN----R 186 Query 190 TVVLEVEFALDPSGRSAPLRYGELIAALNATSGERA-----DPQA-VREAVLALRARKGM 243 VVL +E L G SAPLR+GEL L + E A P A VREAVL LR KGM Sbjct 187 AVVLAIELQLRDDGLSAPLRFGELARRLAVSEQENAAGTVRRPVALVREAVLELRRAKGM 246 Query 244 VLDPTDHDTWSVGSFFTNPVV----TQDVYERLAGDAATRKDGPVPHYPAPDGV-KLAAG 298 V++ TDHDTWS GSFFTNP+V V R+A + + +P YPA +G KL+A Sbjct 247 VVETTDHDTWSAGSFFTNPIVDPALADQVQARVAAERGEEEAARMPRYPAGEGKEKLSAA 306 Query 299 WLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITL 358 WL+ERAGF KG+P +GA LSTKH LALTNRG AT+ED+V LAR +RDGV+ VFG+ L Sbjct 307 WLIERAGFAKGHPGSGAR-AGLSTKHTLALTNRGDATSEDLVALAREIRDGVYAVFGVRL 365 Query 359 KPEPVLIGCML 369 PEPV +G + Sbjct 366 VPEPVWVGVEI 376 >gi|145294515|ref|YP_001137336.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glutamicum R] gi|187609717|sp|A4QB37.1|MURB_CORGB RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase; AltName: Full=UDP-N-acetylmuramate dehydrogenase gi|140844435|dbj|BAF53434.1| hypothetical protein [Corynebacterium glutamicum R] Length=368 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 186/366 (51%), Positives = 235/366 (65%), Gaps = 22/366 (6%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 G + V A LTTLR+G R + C + E +V+A++ LD A+ L+ GGSN Sbjct 15 GVELDSKVTFADLTTLRIGGKPRSAVRCQTTEALVSAIKLLDDASLP----LLIVGGGSN 70 Query 72 LVIAENLTDLTVVRLANSGITID--GNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 LV+A+ D+ V + ++I+ L+ A+AGAV+DDVV +++ GLGG+ECLSGIPG Sbjct 71 LVVADGDLDVIAVIIETDDVSINLTDGLLTADAGAVWDDVVHLSVDAGLGGIECLSGIPG 130 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 SAGATPVQNVGAYG EVSD +TRV+LLDR T +V WV A +L YR S LK + Sbjct 131 SAGATPVQNVGAYGTEVSDVLTRVQLLDRTTHQVSWVDASELDLSYRYSNLKFTN----R 186 Query 190 TVVLEVEFALDPSGRSAPLRYGEL---IAALNATSGERADPQAVREAVLALRARKGMVLD 246 VVL +E L G SAPLR+GEL +A A R + VR+AVL LR KGMV++ Sbjct 187 AVVLAIELQLLTDGLSAPLRFGELGRRLAISEAEPHPRRPVRMVRDAVLELRRAKGMVVE 246 Query 247 PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP--VPHYPAPDGV-KLAAGWLVER 303 TDHDTWS GSFFTNP+V + DA K G +P +PA DG KL+A WL+ER Sbjct 247 HTDHDTWSAGSFFTNPIV-----DPALADAVFEKVGEPTMPRFPAGDGKEKLSAAWLIER 301 Query 304 AGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPV 363 AGF KG+P AG A LSTKH LALTNRG A A D+V LA+ +RDGV + FG+TL PEPV Sbjct 302 AGFKKGHPGAG-AKASLSTKHTLALTNRGDARASDLVALAKEIRDGVLETFGVTLVPEPV 360 Query 364 LIGCML 369 IG + Sbjct 361 WIGISI 366 >gi|29336782|sp|Q8NTB0.1|MURB2_CORGL RecName: Full=UDP-N-acetylenolpyruvoylglucosamine reductase 2; AltName: Full=UDP-N-acetylmuramate dehydrogenase 2 gi|21323162|dbj|BAB97790.1| UDP-N-acetylmuramate dehydrogenase [Corynebacterium glutamicum ATCC 13032] Length=367 Score = 313 bits (803), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 186/366 (51%), Positives = 235/366 (65%), Gaps = 22/366 (6%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 G + V A LTTLR+G R + C + E +V+A++ LD A+ L+ GGSN Sbjct 14 GVELDSEVTFADLTTLRIGGKPRSAVRCQTTEALVSAIKLLDDASLP----LLIVGGGSN 69 Query 72 LVIAENLTDLTVVRLANSGITID--GNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 LV+A+ D+ V + ++I+ L+ A+AGAV+DDVV +++ GLGG+ECLSGIPG Sbjct 70 LVVADGDLDVIAVIIETDDVSINLTDGLLTADAGAVWDDVVHLSVDAGLGGIECLSGIPG 129 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 SAGATPVQNVGAYG EVSD +TRV+LLDR T +V WV A +L YR S LK + Sbjct 130 SAGATPVQNVGAYGTEVSDVLTRVQLLDRTTHQVSWVDASELDLSYRYSNLKFTN----R 185 Query 190 TVVLEVEFALDPSGRSAPLRYGEL---IAALNATSGERADPQAVREAVLALRARKGMVLD 246 VVL +E L G SAPLR+GEL +A A R + VR+AVL LR KGMV++ Sbjct 186 AVVLAIELQLLTDGLSAPLRFGELGRRLAISEAEPHPRRPVRMVRDAVLELRRAKGMVVE 245 Query 247 PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP--VPHYPAPDGV-KLAAGWLVER 303 TDHDTWS GSFFTNP+V + DA K G +P +PA DG KL+A WL+ER Sbjct 246 HTDHDTWSAGSFFTNPIV-----DPALADAVFEKVGEPTMPRFPAGDGKEKLSAAWLIER 300 Query 304 AGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPV 363 AGF KG+P AG A LSTKH LALTNRG A A D+V LA+ +RDGV + FG+TL PEPV Sbjct 301 AGFKKGHPGAG-AKASLSTKHTLALTNRGDARASDLVALAKEIRDGVLETFGVTLVPEPV 359 Query 364 LIGCML 369 IG + Sbjct 360 WIGISI 365 >gi|19551643|ref|NP_599645.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glutamicum ATCC 13032] gi|62389296|ref|YP_224698.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glutamicum ATCC 13032] gi|41324630|emb|CAF19112.1| PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUC [Corynebacterium glutamicum ATCC 13032] gi|344045314|gb|EGV40986.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium glutamicum S9114] Length=368 Score = 313 bits (803), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 186/366 (51%), Positives = 235/366 (65%), Gaps = 22/366 (6%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 G + V A LTTLR+G R + C + E +V+A++ LD A+ L+ GGSN Sbjct 15 GVELDSEVTFADLTTLRIGGKPRSAVRCQTTEALVSAIKLLDDASLP----LLIVGGGSN 70 Query 72 LVIAENLTDLTVVRLANSGITID--GNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 LV+A+ D+ V + ++I+ L+ A+AGAV+DDVV +++ GLGG+ECLSGIPG Sbjct 71 LVVADGDLDVIAVIIETDDVSINLTDGLLTADAGAVWDDVVHLSVDAGLGGIECLSGIPG 130 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 SAGATPVQNVGAYG EVSD +TRV+LLDR T +V WV A +L YR S LK + Sbjct 131 SAGATPVQNVGAYGTEVSDVLTRVQLLDRTTHQVSWVDASELDLSYRYSNLKFTN----R 186 Query 190 TVVLEVEFALDPSGRSAPLRYGEL---IAALNATSGERADPQAVREAVLALRARKGMVLD 246 VVL +E L G SAPLR+GEL +A A R + VR+AVL LR KGMV++ Sbjct 187 AVVLAIELQLLTDGLSAPLRFGELGRRLAISEAEPHPRRPVRMVRDAVLELRRAKGMVVE 246 Query 247 PTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP--VPHYPAPDGV-KLAAGWLVER 303 TDHDTWS GSFFTNP+V + DA K G +P +PA DG KL+A WL+ER Sbjct 247 HTDHDTWSAGSFFTNPIV-----DPALADAVFEKVGEPTMPRFPAGDGKEKLSAAWLIER 301 Query 304 AGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPV 363 AGF KG+P AG A LSTKH LALTNRG A A D+V LA+ +RDGV + FG+TL PEPV Sbjct 302 AGFKKGHPGAG-AKASLSTKHTLALTNRGDARASDLVALAKEIRDGVLETFGVTLVPEPV 360 Query 364 LIGCML 369 IG + Sbjct 361 WIGISI 366 >gi|23492253|dbj|BAC17227.1| putative UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium efficiens YS-314] Length=563 Score = 313 bits (802), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 189/368 (52%), Positives = 234/368 (64%), Gaps = 22/368 (5%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 GA + V A LTTL +G R + C + + V +R LD A+ LV GGSN Sbjct 201 GAELDPDVTFADLTTLHIGGKPRLAVRCATTDAVAQVVRMLDDASVP----LLVVGGGSN 256 Query 72 LVIAENLTDLTVVRLANSGITID--GNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 LV+A+ D+ V + +T++ +V AEAGA +DDVV +++ GLGG+ECLSGIPG Sbjct 257 LVVADGELDVVAVIIEADDVTLNLANGVVVAEAGAEWDDVVSLSVDAGLGGIECLSGIPG 316 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 SAGATPVQNVGAYG E+SD +TRV+LLDR TGEV WV A L YR S LK + Sbjct 317 SAGATPVQNVGAYGVEISDVLTRVQLLDRGTGEVSWVDASSLELAYRYSNLKFTN----R 372 Query 190 TVVLEVEFALDPSGRSAPLRYGELIAALNATSGERA-----DPQA-VREAVLALRARKGM 243 VVL +E L G SAPLR+GEL L + E A P A VREAVL LR KGM Sbjct 373 AVVLAIELQLRDDGLSAPLRFGELARRLAVSEQENAAGTVRRPVALVREAVLELRRAKGM 432 Query 244 VLDPTDHDTWSVGSFFTNPVV----TQDVYERLAGDAATRKDGPVPHYPAPDGV-KLAAG 298 V++ TDHDTWS GSFFTNP+V V R+A + + +P YPA +G KL+A Sbjct 433 VVETTDHDTWSAGSFFTNPIVDPALADQVQARVAAERGEEEAARMPRYPAGEGKEKLSAA 492 Query 299 WLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITL 358 WL+ERAGF KG+P +G A LSTKH LALTNRG AT+ED+V LAR +RDGV+ VFG+ L Sbjct 493 WLIERAGFAKGHPGSG-ARAGLSTKHTLALTNRGDATSEDLVALAREIRDGVYAVFGVRL 551 Query 359 KPEPVLIG 366 PEPV +G Sbjct 552 VPEPVWVG 559 >gi|255324233|ref|ZP_05365355.1| UDP-N-acetylmuramate dehydrogenase [Corynebacterium tuberculostearicum SK141] gi|255298749|gb|EET78044.1| UDP-N-acetylmuramate dehydrogenase [Corynebacterium tuberculostearicum SK141] Length=368 Score = 313 bits (801), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 186/369 (51%), Positives = 229/369 (63%), Gaps = 28/369 (7%) Query 12 GAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSN 71 G + A LTTLRVG + + C+ E VA +R LD A + +V GGSN Sbjct 15 GVELDPTATFADLTTLRVGGKPQAALRCSQPEAAVAVVRALDHAEV----KFIVVGGGSN 70 Query 72 LVIAENLTDLTVVRLANSGITIDGN--LVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPG 129 L++A+ DL V L +++D +VRA+AGAV+DDVV R+++ G+GG+ECLSGIPG Sbjct 71 LLVADGAVDLVAVILDFDEVSMDTETGMVRAQAGAVWDDVVARSVQLGMGGIECLSGIPG 130 Query 130 SAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP 189 + GA PVQNVGAYGAE+S+ +TRVRL +R T WV A DL YR S LK G A Sbjct 131 TVGAVPVQNVGAYGAEISEVLTRVRLYNRRTDADEWVPASDLELAYRYSNLKFT-GRA-- 187 Query 190 TVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTD 249 VVLEVE LD G S PLR+G+ L GER VRE VL LR KGMVLDPTD Sbjct 188 -VVLEVELQLDTEGLSRPLRFGQ----LTQNPGERRPVAEVREEVLKLRRGKGMVLDPTD 242 Query 250 HDTWSVGSFFTNPVVTQDVYERLA-------GDAATRKDGPVPHYPAPD--GVKLAAGWL 300 HDTWS GSFFTNPVV + + + GDA +P +P+ + KL+A WL Sbjct 243 HDTWSAGSFFTNPVVDSALADAVQAKVRASLGDATADS---MPRHPSTETGWEKLSAAWL 299 Query 301 VERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKP 360 ++RAGF KGYP +G A LSTKH LALTNRG A A D+V LAR +RDGV + FG+ L P Sbjct 300 IDRAGFAKGYPGSGRAT--LSTKHTLALTNRGEAKAADIVDLARTIRDGVQETFGVELVP 357 Query 361 EPVLIGCML 369 EPV IG L Sbjct 358 EPVWIGLSL 366 >gi|227505613|ref|ZP_03935662.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium striatum ATCC 6940] gi|227197766|gb|EEI77814.1| UDP-N-acetylenolpyruvoylglucosamine reductase [Corynebacterium striatum ATCC 6940] Length=370 Score = 310 bits (793), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 187/368 (51%), Positives = 218/368 (60%), Gaps = 27/368 (7%) Query 10 FAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGG 69 G + LTTLR+G R + C +AE VAALR L+ LV GG Sbjct 16 ITGVTVEHETTFKDLTTLRIGGSPRATVHCETAEAAVAALRVLEEVPY------LVVGGG 69 Query 70 SNLVIAENLTDLTVVRLANSGI--TIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGI 127 SNLV+AE + VVRL I ++ LVRA+AGA +DDVV +E GLGG+ECLSGI Sbjct 70 SNLVVAEGELEQVVVRLDFDDIDVSVASGLVRADAGATWDDVVSMTVECGLGGIECLSGI 129 Query 128 PGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLA 187 PG AGA PVQNVGAYGAE+SD +T+V L DR TGE WV A L YR S LK Sbjct 130 PGDAGAVPVQNVGAYGAEISDVLTQVYLYDRATGEASWVLAAALELAYRYSNLKFTG--- 186 Query 188 VPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDP 247 VVL +E L G S PLR+G+ L T GER VRE VL+LR KGMVLD Sbjct 187 -RGVVLAIELQLTTDGLSKPLRFGQ----LTQTPGERRPVAEVREQVLSLRRSKGMVLDD 241 Query 248 TDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGP----VPHYPAPDG-----VKLAAG 298 DHDTWS GSFFTNP+V V +R+ T + +P + G +KL+A Sbjct 242 ADHDTWSAGSFFTNPIVESAVADRIQEIVRTERGAEDADRMPRHAVHAGSDGEEIKLSAA 301 Query 299 WLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITL 358 WL+ERAGF KGYP GA P LSTKH LALTNRG ATA DVV LAR +R GV FG+ L Sbjct 302 WLIERAGFAKGYP--GAGPATLSTKHTLALTNRGTATAADVVALAREIRAGVAKRFGVEL 359 Query 359 KPEPVLIG 366 PEPV IG Sbjct 360 VPEPVWIG 367 Lambda K H 0.319 0.136 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 700528985400 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40