BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0484c

Length=251
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607625|ref|NP_214998.1|  short-chain type oxidoreductase [My...   493    1e-137
gi|254230832|ref|ZP_04924159.1|  hypothetical protein TBCG_00476 ...   492    2e-137
gi|31791664|ref|NP_854157.1|  putative short-chain type oxidoredu...   492    3e-137
gi|289573071|ref|ZP_06453298.1|  short-chain type oxidoreductase ...   490    7e-137
gi|340625510|ref|YP_004743962.1|  putative short-chain type oxido...   489    1e-136
gi|183980834|ref|YP_001849125.1|  short-chain type oxidoreductase...   435    2e-120
gi|240169867|ref|ZP_04748526.1|  short-chain type oxidoreductase ...   432    2e-119
gi|118619647|ref|YP_907979.1|  short-chain type oxidoreductase [M...   432    2e-119
gi|289744183|ref|ZP_06503561.1|  oxidoreductase [Mycobacterium tu...   427    5e-118
gi|41410075|ref|NP_962911.1|  hypothetical protein MAP3977c [Myco...   427    8e-118
gi|118464648|ref|YP_883795.1|  oxidoreductase [Mycobacterium aviu...   426    1e-117
gi|336460434|gb|EGO39331.1|  short-chain alcohol dehydrogenase [M...   424    4e-117
gi|296168086|ref|ZP_06850152.1|  serine 3-dehydrogenase [Mycobact...   415    3e-114
gi|342859014|ref|ZP_08715668.1|  hypothetical protein MCOL_09058 ...   409    2e-112
gi|254819812|ref|ZP_05224813.1|  hypothetical protein MintA_07804...   404    6e-111
gi|118468207|ref|YP_885333.1|  serine 3-dehydrogenase [Mycobacter...   397    8e-109
gi|169631139|ref|YP_001704788.1|  putative short chain dehydrogen...   384    7e-105
gi|226305095|ref|YP_002765053.1|  oxidoreductase [Rhodococcus ery...   379    2e-103
gi|111019077|ref|YP_702049.1|  short chain dehydrogenase [Rhodoco...   375    3e-102
gi|120401840|ref|YP_951669.1|  short-chain dehydrogenase/reductas...   374    5e-102
gi|226361170|ref|YP_002778948.1|  oxidoreductase [Rhodococcus opa...   373    1e-101
gi|145220694|ref|YP_001131372.1|  short-chain dehydrogenase/reduc...   366    1e-99 
gi|126433259|ref|YP_001068950.1|  short-chain dehydrogenase/reduc...   365    4e-99 
gi|108797635|ref|YP_637832.1|  short-chain dehydrogenase/reductas...   364    6e-99 
gi|325674055|ref|ZP_08153745.1|  NADP-dependent L-serine/L-allo-t...   364    6e-99 
gi|312141124|ref|YP_004008460.1|  short chain dehydrogenase [Rhod...   364    6e-99 
gi|315442354|ref|YP_004075233.1|  short-chain alcohol dehydrogena...   364    7e-99 
gi|333918294|ref|YP_004491875.1|  serine 3-dehydrogenase [Amycoli...   361    5e-98 
gi|54027168|ref|YP_121410.1|  putative short chain dehydrogenase ...   355    4e-96 
gi|326384030|ref|ZP_08205713.1|  short-chain dehydrogenase/reduct...   342    2e-92 
gi|343925773|ref|ZP_08765288.1|  putative oxidoreductase [Gordoni...   342    2e-92 
gi|262200802|ref|YP_003272010.1|  short-chain dehydrogenase/reduc...   342    3e-92 
gi|319950633|ref|ZP_08024538.1|  oxidoreductase [Dietzia cinnamea...   342    3e-92 
gi|134103402|ref|YP_001109063.1|  short chain dehydrogenase/reduc...   332    4e-89 
gi|333989113|ref|YP_004521727.1|  short-chain dehydrogenase [Myco...   329    2e-88 
gi|291004379|ref|ZP_06562352.1|  short chain dehydrogenase/reduct...   329    3e-88 
gi|256380742|ref|YP_003104402.1|  short-chain dehydrogenase/reduc...   319    3e-85 
gi|324999199|ref|ZP_08120311.1|  short chain dehydrogenase/reduct...   306    2e-81 
gi|331694477|ref|YP_004330716.1|  Serine 3-dehydrogenase [Pseudon...   303    1e-80 
gi|257054340|ref|YP_003132172.1|  short-chain alcohol dehydrogena...   302    2e-80 
gi|296394474|ref|YP_003659358.1|  short-chain dehydrogenase/reduc...   300    1e-79 
gi|317508248|ref|ZP_07965928.1|  short chain dehydrogenase [Segni...   297    1e-78 
gi|296268482|ref|YP_003651114.1|  short-chain dehydrogenase/reduc...   273    2e-71 
gi|237784840|ref|YP_002905545.1|  putative oxidoreductase [Coryne...   265    6e-69 
gi|339293532|gb|AEJ45643.1|  hypothetical protein CCDC5079_0453 [...   263    1e-68 
gi|269124955|ref|YP_003298325.1|  short-chain dehydrogenase/reduc...   263    2e-68 
gi|227487396|ref|ZP_03917712.1|  serine 3-dehydrogenase [Coryneba...   263    2e-68 
gi|271962506|ref|YP_003336702.1|  short-chain alcohol dehydrogena...   263    3e-68 
gi|227541140|ref|ZP_03971189.1|  serine 3-dehydrogenase [Coryneba...   262    3e-68 
gi|332669978|ref|YP_004452986.1|  short-chain dehydrogenase/reduc...   262    4e-68 


>gi|15607625|ref|NP_214998.1| short-chain type oxidoreductase [Mycobacterium tuberculosis H37Rv]
 gi|15839874|ref|NP_334911.1| short chain dehydrogenase/reductase family oxidoreductase [Mycobacterium 
tuberculosis CDC1551]
 gi|148660251|ref|YP_001281774.1| putative short-chain type dehydrogenase/reductase [Mycobacterium 
tuberculosis H37Ra]
 55 more sequence titles
 Length=251

 Score =  493 bits (1269),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 251/251 (100%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
Sbjct  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
Sbjct  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240

Query  241  SASRRATHPVR  251
            SASRRATHPVR
Sbjct  241  SASRRATHPVR  251


>gi|254230832|ref|ZP_04924159.1| hypothetical protein TBCG_00476 [Mycobacterium tuberculosis C]
 gi|124599891|gb|EAY58901.1| hypothetical protein TBCG_00476 [Mycobacterium tuberculosis C]
Length=251

 Score =  492 bits (1266),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 250/251 (99%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAI+AD
Sbjct  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIMAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
Sbjct  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240

Query  241  SASRRATHPVR  251
            SASRRATHPVR
Sbjct  241  SASRRATHPVR  251


>gi|31791664|ref|NP_854157.1| putative short-chain type oxidoreductase [Mycobacterium bovis 
AF2122/97]
 gi|121636400|ref|YP_976623.1| putative short-chain type oxidoreductase [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 gi|224988872|ref|YP_002643559.1| short-chain type oxidoreductase [Mycobacterium bovis BCG str. 
Tokyo 172]
 16 more sequence titles
 Length=251

 Score =  492 bits (1266),  Expect = 3e-137, Method: Compositional matrix adjust.
 Identities = 250/251 (99%), Positives = 251/251 (100%), Gaps = 0/251 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
Sbjct  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
Sbjct  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA+EVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240

Query  241  SASRRATHPVR  251
            SASRRATHPVR
Sbjct  241  SASRRATHPVR  251


>gi|289573071|ref|ZP_06453298.1| short-chain type oxidoreductase [Mycobacterium tuberculosis K85]
 gi|289537502|gb|EFD42080.1| short-chain type oxidoreductase [Mycobacterium tuberculosis K85]
Length=251

 Score =  490 bits (1262),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 249/251 (99%), Positives = 250/251 (99%), Gaps = 0/251 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
Sbjct  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
Sbjct  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA+EVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAP 
Sbjct  121  PKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPS  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240

Query  241  SASRRATHPVR  251
            SASRRATHPVR
Sbjct  241  SASRRATHPVR  251


>gi|340625510|ref|YP_004743962.1| putative short-chain type oxidoreductase [Mycobacterium canettii 
CIPT 140010059]
 gi|340003700|emb|CCC42824.1| putative short-chain type oxidoreductase [Mycobacterium canettii 
CIPT 140010059]
Length=251

 Score =  489 bits (1259),  Expect = 1e-136, Method: Compositional matrix adjust.
 Identities = 249/251 (99%), Positives = 250/251 (99%), Gaps = 0/251 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTTIGT KRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
Sbjct  1    MTTIGTHKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
Sbjct  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA+EVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240

Query  241  SASRRATHPVR  251
            SASRRATHPVR
Sbjct  241  SASRRATHPVR  251


>gi|183980834|ref|YP_001849125.1| short-chain type oxidoreductase [Mycobacterium marinum M]
 gi|183174160|gb|ACC39270.1| short-chain type oxidoreductase [Mycobacterium marinum M]
Length=250

 Score =  435 bits (1119),  Expect = 2e-120, Method: Compositional matrix adjust.
 Identities = 222/250 (89%), Positives = 233/250 (94%), Gaps = 0/250 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT     RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITAL +QIGGT IVAD
Sbjct  1    MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALTDQIGGTPIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD AAV ALA  LSRVDVLVNNAGGAKGL+ VADADLEHWRWMW+TNVLGTLRVTRALL
Sbjct  61   VTDGAAVAALADGLSRVDVLVNNAGGAKGLEPVADADLEHWRWMWETNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLI SGDGLIVTVTSIAA+E+YDGGAGYTAAKHAQGALHRTLRGELLG PVRLTEIAPG
Sbjct  121  PKLIASGDGLIVTVTSIAALEIYDGGAGYTAAKHAQGALHRTLRGELLGLPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGD+QRADAVY+GMTPLVAAD+AEVIGFVA+RP HVNLDQI+IRPRDQA
Sbjct  181  AVETEFSLVRFDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNLDQIIIRPRDQA  240

Query  241  SASRRATHPV  250
            SA+RRA H V
Sbjct  241  SATRRANHQV  250


>gi|240169867|ref|ZP_04748526.1| short-chain type oxidoreductase [Mycobacterium kansasii ATCC 
12478]
Length=252

 Score =  432 bits (1112),  Expect = 2e-119, Method: Compositional matrix adjust.
 Identities = 221/249 (89%), Positives = 237/249 (96%), Gaps = 0/249 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT     RVAVVTGASSGIGEATA+ LAAQGFHVVAVARRADRI+ LA+QIGGTA+VAD
Sbjct  1    MTTPDAPNRVAVVTGASSGIGEATAKNLAAQGFHVVAVARRADRISDLADQIGGTAVVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            +TDDAAV ALA  LSRVDVLVNNAGGAKGL+ VADADL+HWRWMW+TNVLGTLRVTRALL
Sbjct  61   ITDDAAVAALAAGLSRVDVLVNNAGGAKGLELVADADLQHWRWMWETNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLI+SGDGLIVTVTSIAA+EVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIESGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGD+QRADAVY+GMTPLVAAD+AEVIGFVA+RPSHVNLDQI+IRPRDQA
Sbjct  181  AVETEFSLVRFDGDRQRADAVYSGMTPLVAADIAEVIGFVASRPSHVNLDQIIIRPRDQA  240

Query  241  SASRRATHP  249
            SA+RRA HP
Sbjct  241  SATRRANHP  249


>gi|118619647|ref|YP_907979.1| short-chain type oxidoreductase [Mycobacterium ulcerans Agy99]
 gi|118571757|gb|ABL06508.1| short-chain type oxidoreductase [Mycobacterium ulcerans Agy99]
Length=250

 Score =  432 bits (1112),  Expect = 2e-119, Method: Compositional matrix adjust.
 Identities = 221/250 (89%), Positives = 232/250 (93%), Gaps = 0/250 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT     RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITAL +QIGGT IVAD
Sbjct  1    MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALTDQIGGTPIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD AAV ALA  LSRVDVLVNNAGGAK L+ VADADLEHWRWMW+TNVLGTLRVTRALL
Sbjct  61   VTDGAAVAALADGLSRVDVLVNNAGGAKELEPVADADLEHWRWMWETNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLI SGDGLIVTVTSIAA+E+YDGGAGYTAAKHAQGALHRTLRGELLG PVRLTEIAPG
Sbjct  121  PKLIASGDGLIVTVTSIAALEIYDGGAGYTAAKHAQGALHRTLRGELLGLPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGD+QRADAVY+GMTPLVAAD+AEVIGFVA+RP HVNLDQI+IRPRDQA
Sbjct  181  AVETEFSLVRFDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNLDQIIIRPRDQA  240

Query  241  SASRRATHPV  250
            SA+RRA H V
Sbjct  241  SATRRANHQV  250


>gi|289744183|ref|ZP_06503561.1| oxidoreductase [Mycobacterium tuberculosis 02_1987]
 gi|289684711|gb|EFD52199.1| oxidoreductase [Mycobacterium tuberculosis 02_1987]
Length=217

 Score =  427 bits (1099),  Expect = 5e-118, Method: Compositional matrix adjust.
 Identities = 216/217 (99%), Positives = 217/217 (100%), Gaps = 0/217 (0%)

Query  35   VVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVA  94
            +VAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVA
Sbjct  1    MVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVA  60

Query  95   DADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKH  154
            DADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKH
Sbjct  61   DADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKH  120

Query  155  AQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVA  214
            AQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVA
Sbjct  121  AQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVA  180

Query  215  EVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR  251
            EVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR
Sbjct  181  EVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR  217


>gi|41410075|ref|NP_962911.1| hypothetical protein MAP3977c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|254777103|ref|ZP_05218619.1| hypothetical protein MaviaA2_20889 [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|41398908|gb|AAS06527.1| hypothetical protein MAP_3977c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=249

 Score =  427 bits (1097),  Expect = 8e-118, Method: Compositional matrix adjust.
 Identities = 215/244 (89%), Positives = 231/244 (95%), Gaps = 0/244 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            M   G  +RVAVVTGASSGIGEATARTLAAQGFHVVAVARRA+RI ALAN+IGGTAIVAD
Sbjct  1    MVGTGRNERVAVVTGASSGIGEATARTLAAQGFHVVAVARRAERIHALANEIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAV ALA  LSRVDVLVNNAGGA+GL+ VA+ADLEHWRWMW+TNV+GTLRVTRALL
Sbjct  61   VTDDAAVAALASKLSRVDVLVNNAGGARGLEPVAEADLEHWRWMWETNVIGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKL+DSGDGLIVTVTS+AA+EVYDGGAGYTAAKH QGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLVDSGDGLIVTVTSVAALEVYDGGAGYTAAKHGQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVY G+TPLVAADVAEVIGFVA+RP+HVNLD IV++PRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYTGITPLVAADVAEVIGFVASRPAHVNLDLIVMKPRDQA  240

Query  241  SASR  244
            SASR
Sbjct  241  SASR  244


>gi|118464648|ref|YP_883795.1| oxidoreductase [Mycobacterium avium 104]
 gi|118165935|gb|ABK66832.1| oxidoreductase [Mycobacterium avium 104]
Length=249

 Score =  426 bits (1096),  Expect = 1e-117, Method: Compositional matrix adjust.
 Identities = 215/244 (89%), Positives = 230/244 (95%), Gaps = 0/244 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            M   G  +RVAVVTGASSGIGEATARTLAAQGFHVVAVARRA RI ALAN+IGGTAIVAD
Sbjct  1    MVGTGRNERVAVVTGASSGIGEATARTLAAQGFHVVAVARRAKRIHALANEIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAV ALA  LSRVDVLVNNAGGA+GL+ VA+ADLEHWRWMW+TNV+GTLRVTRALL
Sbjct  61   VTDDAAVAALASKLSRVDVLVNNAGGARGLEPVAEADLEHWRWMWETNVIGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKL+DSGDGLIVTVTS+AA+EVYDGGAGYTAAKH QGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLVDSGDGLIVTVTSVAALEVYDGGAGYTAAKHGQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVY G+TPLVAADVAEVIGFVA+RP+HVNLD IV++PRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYTGITPLVAADVAEVIGFVASRPAHVNLDLIVMKPRDQA  240

Query  241  SASR  244
            SASR
Sbjct  241  SASR  244


>gi|336460434|gb|EGO39331.1| short-chain alcohol dehydrogenase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=249

 Score =  424 bits (1091),  Expect = 4e-117, Method: Compositional matrix adjust.
 Identities = 214/244 (88%), Positives = 231/244 (95%), Gaps = 0/244 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            M   G  +RVAVVTGASSGIGEATARTLAAQGFHVVAVARRA+RI ALAN+IGGTAIVAD
Sbjct  1    MVGTGRNERVAVVTGASSGIGEATARTLAAQGFHVVAVARRAERIHALANEIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAV ALA  LSRVDVLVNNAGGA+GL+ VA+ADLEHWRWMW+T+V+GTLRVTRALL
Sbjct  61   VTDDAAVAALASKLSRVDVLVNNAGGARGLEPVAEADLEHWRWMWETDVIGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKL+DSGDGLIVTVTS+AA+EVYDGGAGYTAAKH QGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLVDSGDGLIVTVTSVAALEVYDGGAGYTAAKHGQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQQRADAVY G+TPLVAADVAEVIGFVA+RP+HVNLD IV++PRDQA
Sbjct  181  AVETEFSLVRFDGDQQRADAVYTGITPLVAADVAEVIGFVASRPAHVNLDLIVMKPRDQA  240

Query  241  SASR  244
            SASR
Sbjct  241  SASR  244


>gi|296168086|ref|ZP_06850152.1| serine 3-dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295896893|gb|EFG76521.1| serine 3-dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=249

 Score =  415 bits (1067),  Expect = 3e-114, Method: Compositional matrix adjust.
 Identities = 209/237 (89%), Positives = 226/237 (96%), Gaps = 0/237 (0%)

Query  8    KRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAV  67
            +RVAVVTGASSGIGEATA+TLAAQGFHVVAVARRADRI ALA +IGGTAIVADVTDDAAV
Sbjct  8    ERVAVVTGASSGIGEATAQTLAAQGFHVVAVARRADRINALAREIGGTAIVADVTDDAAV  67

Query  68   EALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSG  127
             ALA  LSRVDVLVNNAGGA+GL  VAD+DLEHWRWMW+TNV+GTLRVTRALLPKL++SG
Sbjct  68   AALAGELSRVDVLVNNAGGARGLAPVADSDLEHWRWMWETNVMGTLRVTRALLPKLVESG  127

Query  128  DGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFS  187
            DGLIVTVTS+AA+EVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTE+APGAVETEFS
Sbjct  128  DGLIVTVTSVAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEVAPGAVETEFS  187

Query  188  LVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            LVRFDGDQQRADAVY G+TPLVA DVAEVIGFVA RPSHV+LD IV++PRDQASA+R
Sbjct  188  LVRFDGDQQRADAVYTGITPLVAQDVAEVIGFVAARPSHVDLDLIVMKPRDQASATR  244


>gi|342859014|ref|ZP_08715668.1| hypothetical protein MCOL_09058 [Mycobacterium colombiense CECT 
3035]
 gi|342133255|gb|EGT86458.1| hypothetical protein MCOL_09058 [Mycobacterium colombiense CECT 
3035]
Length=249

 Score =  409 bits (1051),  Expect = 2e-112, Method: Compositional matrix adjust.
 Identities = 204/244 (84%), Positives = 225/244 (93%), Gaps = 0/244 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            M   G  KRVAV+TGASSGIG ATAR LAAQGFHVVAVARRADRI ALA++IGGTAIVAD
Sbjct  1    MVKTGRNKRVAVITGASSGIGAATARNLAAQGFHVVAVARRADRIEALASEIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD A+VE LA  L RVDVLVNNAGGA+GL  VA+A+LEHW+WMW+TNV+GTLRVTRALL
Sbjct  61   VTDGASVETLASKLERVDVLVNNAGGARGLAPVAEAELEHWQWMWETNVIGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLI+SGDGLIVTVTS+AA+EVYDGGAGYTAAKHAQGA+HRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIESGDGLIVTVTSVAALEVYDGGAGYTAAKHAQGAMHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGDQ+RADAVY G+TPLVA DVAEVIGFVA+RPSHV+LD IV++PRDQA
Sbjct  181  AVETEFSLVRFDGDQERADAVYTGITPLVADDVAEVIGFVASRPSHVDLDLIVMKPRDQA  240

Query  241  SASR  244
            + SR
Sbjct  241  TTSR  244


>gi|254819812|ref|ZP_05224813.1| hypothetical protein MintA_07804 [Mycobacterium intracellulare 
ATCC 13950]
Length=238

 Score =  404 bits (1038),  Expect = 6e-111, Method: Compositional matrix adjust.
 Identities = 202/233 (87%), Positives = 222/233 (96%), Gaps = 0/233 (0%)

Query  12   VVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALA  71
            ++TGASSGIG ATARTLAAQGFH+VAVARRADRI  LA +IGGTAIVADVTDDA+V+ALA
Sbjct  1    MITGASSGIGAATARTLAAQGFHIVAVARRADRIHDLAEEIGGTAIVADVTDDASVDALA  60

Query  72   RALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLI  131
              LSRVDVLVNNAGGA+GL+ VADADL+HWRWMW+TNV+GTLRVTRALLPKLI+SGDGLI
Sbjct  61   SKLSRVDVLVNNAGGARGLEPVADADLDHWRWMWETNVIGTLRVTRALLPKLIESGDGLI  120

Query  132  VTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRF  191
            VTVTS+AA+EVYDGGAGYTAAKH QGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRF
Sbjct  121  VTVTSVAALEVYDGGAGYTAAKHGQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRF  180

Query  192  DGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            DGDQQRADAVY G+TPLVAADVAEVI FVA+RP+HV+LD IV++PRDQASASR
Sbjct  181  DGDQQRADAVYTGITPLVAADVAEVIEFVASRPAHVDLDLIVMKPRDQASASR  233


>gi|118468207|ref|YP_885333.1| serine 3-dehydrogenase [Mycobacterium smegmatis str. MC2 155]
 gi|118169494|gb|ABK70390.1| serine 3-dehydrogenase [Mycobacterium smegmatis str. MC2 155]
Length=249

 Score =  397 bits (1020),  Expect = 8e-109, Method: Compositional matrix adjust.
 Identities = 199/244 (82%), Positives = 218/244 (90%), Gaps = 0/244 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            M+T  + + VAVVTGAS+GIG ATA+TLA+ GFHV+  ARRADRI ALA +I GTA+VAD
Sbjct  1    MSTPHSDRPVAVVTGASAGIGAATAKTLASLGFHVICAARRADRIDALAKEIDGTAVVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDD +V ALA  L RVDVLVNNAGGAKGL  V+DADL+HWRWMW+TNVLGTLRVTRALL
Sbjct  61   VTDDESVNALAAQLDRVDVLVNNAGGAKGLAPVSDADLDHWRWMWETNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA E YDGGAGYT+AKHAQGALHRTLRGELLGKPVRLTEIAPG
Sbjct  121  PKLIDSGDGLIVTVTSIAAFETYDGGAGYTSAKHAQGALHRTLRGELLGKPVRLTEIAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFSLVRFDGD++RAD VY G+TPLVA D+AEVIGFVA+RPSHVNLDQIVIRPRDQA
Sbjct  181  AVETEFSLVRFDGDRERADNVYKGITPLVAEDIAEVIGFVASRPSHVNLDQIVIRPRDQA  240

Query  241  SASR  244
               R
Sbjct  241  PNGR  244


>gi|169631139|ref|YP_001704788.1| putative short chain dehydrogenase/reductase [Mycobacterium abscessus 
ATCC 19977]
 gi|169243106|emb|CAM64134.1| Putative short chain dehydrogenase/reductase [Mycobacterium abscessus]
Length=249

 Score =  384 bits (986),  Expect = 7e-105, Method: Compositional matrix adjust.
 Identities = 192/247 (78%), Positives = 218/247 (89%), Gaps = 0/247 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MT      RVAVVTGASSGIG ATA++LAA GFHVV  ARR DR+ +LA +IGGTA V D
Sbjct  1    MTNPTFDGRVAVVTGASSGIGAATAKSLAALGFHVVVAARREDRVKSLAGEIGGTAFVLD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD  +V AL ++L RVDVLVNNAGGA GL+ V +ADLEHWRWMW+TNV+GTL+VTRALL
Sbjct  61   VTDADSVAALTQSLDRVDVLVNNAGGAWGLEPVLEADLEHWRWMWETNVVGTLQVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA++VYDGG+GYT+AKHAQ ALHRTLRGELLGKPVRLTE+APG
Sbjct  121  PKLIDSGDGLIVTVTSIAALDVYDGGSGYTSAKHAQAALHRTLRGELLGKPVRLTEVAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
            AVETEFS+VRFDGDQ RADAVY G+TPLVA DVAE+I FVA+RP HVNLDQIV++PRDQA
Sbjct  181  AVETEFSVVRFDGDQDRADAVYRGITPLVAEDVAEIIAFVASRPPHVNLDQIVVKPRDQA  240

Query  241  SASRRAT  247
            S++RRAT
Sbjct  241  SSTRRAT  247


>gi|226305095|ref|YP_002765053.1| oxidoreductase [Rhodococcus erythropolis PR4]
 gi|229490743|ref|ZP_04384581.1| serine 3-dehydrogenase [Rhodococcus erythropolis SK121]
 gi|226184210|dbj|BAH32314.1| putative oxidoreductase [Rhodococcus erythropolis PR4]
 gi|229322563|gb|EEN88346.1| serine 3-dehydrogenase [Rhodococcus erythropolis SK121]
Length=249

 Score =  379 bits (974),  Expect = 2e-103, Method: Compositional matrix adjust.
 Identities = 184/242 (77%), Positives = 211/242 (88%), Gaps = 0/242 (0%)

Query  3    TIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVT  62
            TI +  R+AVVTGASSGIGEATARTLAAQGFHVV  ARR DR+  +A +IGGTA+  DVT
Sbjct  2    TISSDARIAVVTGASSGIGEATARTLAAQGFHVVIGARRVDRLEKIAEEIGGTALELDVT  61

Query  63   DDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPK  122
            D+ +V+A A  + RVDVLVNNAGGAKGL  V DADL+ WRWMW+TNVLGTLRVT+ALLPK
Sbjct  62   DEDSVDAFAAVVPRVDVLVNNAGGAKGLATVLDADLDDWRWMWETNVLGTLRVTKALLPK  121

Query  123  LIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAV  182
            LIDSGDGL+VT+TS+AA+E YD G+GYT AKHAQ  LHRTLRGELLGKPVRLTEIAPGAV
Sbjct  122  LIDSGDGLVVTITSVAALEAYDNGSGYTTAKHAQAVLHRTLRGELLGKPVRLTEIAPGAV  181

Query  183  ETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASA  242
            ETEFSLVRF+GDQ +AD VY G+TPLVA D+AE+IGFVA+RPSHVNLDQI+++PRDQAS 
Sbjct  182  ETEFSLVRFEGDQDKADKVYEGITPLVAQDIAEIIGFVASRPSHVNLDQIIVKPRDQASP  241

Query  243  SR  244
             R
Sbjct  242  GR  243


>gi|111019077|ref|YP_702049.1| short chain dehydrogenase [Rhodococcus jostii RHA1]
 gi|110818607|gb|ABG93891.1| short chain dehydrogenase [Rhodococcus jostii RHA1]
Length=248

 Score =  375 bits (963),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 183/242 (76%), Positives = 211/242 (88%), Gaps = 0/242 (0%)

Query  3    TIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVT  62
            T     R+AVVTGASSGIGEATARTLAAQGFHVV  ARR DR+  +A  IGGTA+  DVT
Sbjct  2    TFSPDTRIAVVTGASSGIGEATARTLAAQGFHVVIGARRLDRLEKIAEDIGGTALELDVT  61

Query  63   DDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPK  122
            D  +V+A +  L RVDVLVNNAGGAKGL  VA+ADL+ WRWMW+TNVLGTLR+T+ALLPK
Sbjct  62   DQDSVDAFSAVLPRVDVLVNNAGGAKGLATVAEADLDDWRWMWETNVLGTLRITKALLPK  121

Query  123  LIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAV  182
            LI+SGDGLIVT+TS+AA+E YD G+GYT AKHA+  LHRTLRGELLGKPVRLTEIAPGAV
Sbjct  122  LIESGDGLIVTITSLAALEAYDNGSGYTTAKHAEAVLHRTLRGELLGKPVRLTEIAPGAV  181

Query  183  ETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASA  242
            ETEFSLVRF+GDQ+RAD VY G+TPLVAADVA+V+GFVA+RPSHVN+DQIV++PRDQAS+
Sbjct  182  ETEFSLVRFEGDQERADKVYEGITPLVAADVADVVGFVASRPSHVNIDQIVVKPRDQASS  241

Query  243  SR  244
             R
Sbjct  242  GR  243


>gi|120401840|ref|YP_951669.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii 
PYR-1]
 gi|119954658|gb|ABM11663.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii 
PYR-1]
Length=252

 Score =  374 bits (961),  Expect = 5e-102, Method: Compositional matrix adjust.
 Identities = 190/243 (79%), Positives = 210/243 (87%), Gaps = 0/243 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT    +RVAVVTGAS+GIGEATARTLAAQGFHV+ VARR   I ALA +I GTAIVAD
Sbjct  1    MTTPTDARRVAVVTGASAGIGEATARTLAAQGFHVICVARREAPIQALAAEIDGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD  AV ALA  L RVDVLVNNAGGA+GL+ VADAD+EHWRWMW+ NVLGTL VTRALL
Sbjct  61   VTDPTAVAALAGRLDRVDVLVNNAGGARGLESVADADVEHWRWMWEANVLGTLHVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLI SGDGLIVTVTSIAA+E+YD GAGYT+AKHAQG LHRTLR ELLGKPVRLTE+APG
Sbjct  121  PKLIGSGDGLIVTVTSIAAVEIYDNGAGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
             V+TEFSL RFDGD +RAD VY G+TPLVA D+AEVIGFVA+RPSHV+LD IV+RPRDQ 
Sbjct  181  MVKTEFSLNRFDGDAERADKVYQGVTPLVAEDIAEVIGFVASRPSHVDLDLIVVRPRDQV  240

Query  241  SAS  243
            S +
Sbjct  241  SGA  243


>gi|226361170|ref|YP_002778948.1| oxidoreductase [Rhodococcus opacus B4]
 gi|226239655|dbj|BAH50003.1| putative oxidoreductase [Rhodococcus opacus B4]
Length=248

 Score =  373 bits (958),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 184/242 (77%), Positives = 209/242 (87%), Gaps = 0/242 (0%)

Query  3    TIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVT  62
            T     R+AVVTGASSGIGEATARTLA QGFHVV  ARR DR+  +A  IGGTA+  DVT
Sbjct  2    TFSPDTRIAVVTGASSGIGEATARTLAEQGFHVVIGARRLDRLEKIAEDIGGTALELDVT  61

Query  63   DDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPK  122
            D  +V+A A  L RVDVLVNNAGGAKGL  VA+ADL+ WRWMW+TNVLGTLRVT+ALLPK
Sbjct  62   DQDSVDAFAAVLPRVDVLVNNAGGAKGLATVAEADLDDWRWMWETNVLGTLRVTKALLPK  121

Query  123  LIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAV  182
            LI+SGDGL+VTVTS+AA+E YD G+GYT AKHA+  LHRTLRGELLGKPVRLTEIAPGAV
Sbjct  122  LIESGDGLVVTVTSLAALEAYDNGSGYTTAKHAEAVLHRTLRGELLGKPVRLTEIAPGAV  181

Query  183  ETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASA  242
            ETEFSLVRF+GDQ+RAD VYAG+TPLVA DVA+VIGFVA+RP HVN+DQIV++PRDQAS+
Sbjct  182  ETEFSLVRFEGDQERADKVYAGITPLVATDVADVIGFVASRPPHVNIDQIVVKPRDQASS  241

Query  243  SR  244
             R
Sbjct  242  GR  243


>gi|145220694|ref|YP_001131372.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum 
PYR-GCK]
 gi|145213180|gb|ABP42584.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum 
PYR-GCK]
Length=252

 Score =  366 bits (940),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 181/243 (75%), Positives = 209/243 (87%), Gaps = 0/243 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT    +RVAVVTGAS+GIGEA ARTLAAQGFHV+ VARR   I ALA +I GTAIVAD
Sbjct  1    MTTPSDARRVAVVTGASAGIGEAIARTLAAQGFHVICVARREGPIKALAAEIDGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD  AV ALA  L RVDVLVNNAGGA+GL+ ++DAD+E+WRWMW+ NV+GTL VTRALL
Sbjct  61   VTDPTAVAALAGRLDRVDVLVNNAGGARGLESISDADVENWRWMWEANVMGTLHVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVT+TSIAA+E+YD G GYT+AKHAQG LHRTLR ELLGKPVRLTE+APG
Sbjct  121  PKLIDSGDGLIVTITSIAAVEIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
             V+T+FSL RFDGD +RA+ VY G+TPLVA D+AEV+GFVA+RPSHV+LD IV+RPRDQ 
Sbjct  181  MVKTDFSLNRFDGDAERAEKVYEGVTPLVAEDIAEVVGFVASRPSHVDLDLIVVRPRDQV  240

Query  241  SAS  243
            S +
Sbjct  241  SGA  243


>gi|126433259|ref|YP_001068950.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS]
 gi|126233059|gb|ABN96459.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS]
Length=251

 Score =  365 bits (936),  Expect = 4e-99, Method: Compositional matrix adjust.
 Identities = 188/243 (78%), Positives = 215/243 (89%), Gaps = 0/243 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT    +RVAVVTGAS+GIGEATARTLAAQGFHVV VARR + I ALA++IGGTAIVAD
Sbjct  1    MTTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VT   AV+ALA AL RVDVLVNNAGGA+GL  +A+AD+EHWRWMW++NVLGTL VTRALL
Sbjct  61   VTSTEAVDALAAALDRVDVLVNNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA+E+YD G GYT+AKHAQG LHRTLR ELLGKPVRLTE+APG
Sbjct  121  PKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
             V+T+FSL RF+GD++RA+ VY G+TPLVA D+AEVIGFVA+RPSHV+LD IVIRPRDQ 
Sbjct  181  MVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQV  240

Query  241  SAS  243
            S +
Sbjct  241  SGA  243


>gi|108797635|ref|YP_637832.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS]
 gi|119866722|ref|YP_936674.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS]
 gi|108768054|gb|ABG06776.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS]
 gi|119692811|gb|ABL89884.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS]
Length=251

 Score =  364 bits (935),  Expect = 6e-99, Method: Compositional matrix adjust.
 Identities = 187/243 (77%), Positives = 215/243 (89%), Gaps = 0/243 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT    +RVAVVTGAS+GIGEATARTLAAQGFHVV VARR + I ALA++IGGTA+VAD
Sbjct  1    MTTSRGDQRVAVVTGASAGIGEATARTLAAQGFHVVCVARREEPIKALADEIGGTAVVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VT   AV+ALA AL RVDVLVNNAGGA+GL  +A+AD+EHWRWMW++NVLGTL VTRALL
Sbjct  61   VTSTEAVDALAAALDRVDVLVNNAGGARGLDPIAEADIEHWRWMWESNVLGTLLVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVTVTSIAA+E+YD G GYT+AKHAQG LHRTLR ELLGKPVRLTE+APG
Sbjct  121  PKLIDSGDGLIVTVTSIAAVEIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
             V+T+FSL RF+GD++RA+ VY G+TPLVA D+AEVIGFVA+RPSHV+LD IVIRPRDQ 
Sbjct  181  MVKTDFSLNRFEGDEERAEKVYEGVTPLVAEDIAEVIGFVASRPSHVDLDLIVIRPRDQV  240

Query  241  SAS  243
            S +
Sbjct  241  SGA  243


>gi|325674055|ref|ZP_08153745.1| NADP-dependent L-serine/L-allo-threonine dehydrogenase YdfG [Rhodococcus 
equi ATCC 33707]
 gi|325555320|gb|EGD24992.1| NADP-dependent L-serine/L-allo-threonine dehydrogenase YdfG [Rhodococcus 
equi ATCC 33707]
Length=249

 Score =  364 bits (935),  Expect = 6e-99, Method: Compositional matrix adjust.
 Identities = 180/236 (77%), Positives = 202/236 (86%), Gaps = 0/236 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            RVAVVTGASSGIGEATARTLA QGFHVV  ARR DR+ A+A +IGGTA+  DVTD+ +V+
Sbjct  8    RVAVVTGASSGIGEATARTLAGQGFHVVLGARRLDRLEAIAAEIGGTALELDVTDEDSVD  67

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            A    L RVDVLVNNAGGAKGL  V DADL+ WRWMW+TNVLGTLRVT+ALLPKLI SGD
Sbjct  68   AFCAVLPRVDVLVNNAGGAKGLAPVMDADLDDWRWMWETNVLGTLRVTKALLPKLIASGD  127

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            GLIVTVTS+AA   YD GAGYT+AKHAQ  LHRTLRGELLGKPVRLTEIAPGAVETEFSL
Sbjct  128  GLIVTVTSVAAFTAYDNGAGYTSAKHAQAVLHRTLRGELLGKPVRLTEIAPGAVETEFSL  187

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            VRFDGD +RA  VY G+TPL+A D+AE++GFVA+RP HVNLDQI+++PRDQA   R
Sbjct  188  VRFDGDAERAAKVYEGITPLIAEDIAEIVGFVASRPPHVNLDQIIVKPRDQADTGR  243


>gi|312141124|ref|YP_004008460.1| short chain dehydrogenase [Rhodococcus equi 103S]
 gi|311890463|emb|CBH49781.1| short chain dehydrogenase [Rhodococcus equi 103S]
Length=282

 Score =  364 bits (935),  Expect = 6e-99, Method: Compositional matrix adjust.
 Identities = 180/236 (77%), Positives = 202/236 (86%), Gaps = 0/236 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            RVAVVTGASSGIGEATARTLA QGFHVV  ARR DR+ A+A +IGGTA+  DVTD+ +V+
Sbjct  41   RVAVVTGASSGIGEATARTLAGQGFHVVLGARRLDRLEAIAAEIGGTALELDVTDEDSVD  100

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            A    L RVDVLVNNAGGAKGL  V DADL+ WRWMW+TNVLGTLRVT+ALLPKLI SGD
Sbjct  101  AFCAVLPRVDVLVNNAGGAKGLAPVMDADLDDWRWMWETNVLGTLRVTKALLPKLIASGD  160

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            GLIVTVTS+AA   YD GAGYT+AKHAQ  LHRTLRGELLGKPVRLTEIAPGAVETEFSL
Sbjct  161  GLIVTVTSVAAFTAYDNGAGYTSAKHAQAVLHRTLRGELLGKPVRLTEIAPGAVETEFSL  220

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            VRFDGD +RA  VY G+TPL+A D+AE++GFVA+RP HVNLDQI+++PRDQA   R
Sbjct  221  VRFDGDAERAAKVYEGITPLIAEDIAEIVGFVASRPPHVNLDQIIVKPRDQADTGR  276


>gi|315442354|ref|YP_004075233.1| short-chain alcohol dehydrogenase [Mycobacterium sp. Spyr1]
 gi|315260657|gb|ADT97398.1| short-chain alcohol dehydrogenase [Mycobacterium sp. Spyr1]
Length=252

 Score =  364 bits (934),  Expect = 7e-99, Method: Compositional matrix adjust.
 Identities = 180/243 (75%), Positives = 208/243 (86%), Gaps = 0/243 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTT    +RVAVVTGAS+GIGEA AR LAAQGFHV+ VARR   I ALA +I GTAIVAD
Sbjct  1    MTTPSDTRRVAVVTGASAGIGEAIARNLAAQGFHVICVARREAPIKALAAEIDGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD  AV ALA  L RVDV+VNNAGGA+GL+ +ADAD+E+WRWMW+ NV+GTL VTRALL
Sbjct  61   VTDPTAVAALAGRLDRVDVVVNNAGGARGLESIADADVENWRWMWEANVMGTLHVTRALL  120

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            PKLIDSGDGLIVT+TSIAA+E+YD G GYT+AKHAQG LHRTLR ELLGKPVRLTE+APG
Sbjct  121  PKLIDSGDGLIVTITSIAAVEIYDNGGGYTSAKHAQGVLHRTLRSELLGKPVRLTEVAPG  180

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
             V+T+FSL RFDGD +RA+ VY G+TPLVA D+AEV+GFVA+RPSHV+LD IV+RPRDQ 
Sbjct  181  MVKTDFSLNRFDGDAERAEKVYEGVTPLVAEDIAEVVGFVASRPSHVDLDLIVVRPRDQV  240

Query  241  SAS  243
            S +
Sbjct  241  SGA  243


>gi|333918294|ref|YP_004491875.1| serine 3-dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333480515|gb|AEF39075.1| Serine 3-dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
Length=259

 Score =  361 bits (927),  Expect = 5e-98, Method: Compositional matrix adjust.
 Identities = 178/248 (72%), Positives = 204/248 (83%), Gaps = 0/248 (0%)

Query  4    IGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTD  63
            I    RVAVVTGASSGIGEATARTLA  GFHV+  ARR DRI ALA +I GTA+  DVTD
Sbjct  11   IAENTRVAVVTGASSGIGEATARTLADSGFHVIVGARRVDRIEALAQEISGTALPLDVTD  70

Query  64   DAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKL  123
            D +V A   A+ RV VLVNNAGGAKGL+ V +ADL++WRWMW+TNVLGTLR+T+ALLPKL
Sbjct  71   DESVHAFTTAIPRVSVLVNNAGGAKGLETVMEADLDNWRWMWETNVLGTLRMTKALLPKL  130

Query  124  IDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVE  183
            IDSGDGLIVTVTSIAA+E+Y GG+GYT+AKHAQG LHRTLR EL GKPVRLTE+APGAVE
Sbjct  131  IDSGDGLIVTVTSIAALEIYSGGSGYTSAKHAQGVLHRTLRDELHGKPVRLTEVAPGAVE  190

Query  184  TEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASAS  243
            TEFS VRF+GD +RA  VY G TPL A D+AEVIGFVATRPSHVN+DQ++I+PR QA   
Sbjct  191  TEFSKVRFEGDDERAAKVYEGFTPLSADDIAEVIGFVATRPSHVNIDQVMIKPRAQAGPG  250

Query  244  RRATHPVR  251
            +    P +
Sbjct  251  KFHREPAQ  258


>gi|54027168|ref|YP_121410.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152]
 gi|54018676|dbj|BAD60046.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152]
Length=244

 Score =  355 bits (910),  Expect = 4e-96, Method: Compositional matrix adjust.
 Identities = 175/238 (74%), Positives = 200/238 (85%), Gaps = 0/238 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            R AVVTGASSGIGEATAR LAA G+HV   ARR DR+  LA +IGGTA+  DVT + +V 
Sbjct  4    RTAVVTGASSGIGEATARQLAADGYHVYVGARRMDRLRTLAEEIGGTALELDVTSEDSVR  63

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            A   A+ RVDVLVNNAGGAKGL  VA+ADL+ WRWMW+TNVLGTLRVT+ALLPKLIDSGD
Sbjct  64   AFTDAVERVDVLVNNAGGAKGLAPVAEADLDDWRWMWETNVLGTLRVTKALLPKLIDSGD  123

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            GLIVT+TS+AA   YD G+GYT+AKHAQ  LHRTLRGELLG+PVRLTEIAPGAVETEFSL
Sbjct  124  GLIVTITSVAAFHAYDNGSGYTSAKHAQAVLHRTLRGELLGQPVRLTEIAPGAVETEFSL  183

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRA  246
            VRFDGD +RA  VY G+ PLVAAD+AE++GFVA+RP HVNLDQI+++PRDQA   R A
Sbjct  184  VRFDGDAERAAKVYEGIDPLVAADIAEIVGFVASRPPHVNLDQIIVKPRDQADPGRFA  241


>gi|326384030|ref|ZP_08205713.1| short-chain dehydrogenase/reductase SDR [Gordonia neofelifaecis 
NRRL B-59395]
 gi|326197190|gb|EGD54381.1| short-chain dehydrogenase/reductase SDR [Gordonia neofelifaecis 
NRRL B-59395]
Length=253

 Score =  342 bits (878),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 169/236 (72%), Positives = 197/236 (84%), Gaps = 0/236 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            RVAVVTGASSGIG ATAR+LA  G+ VV  ARR DR+ ALA +IGG A+  DVTD A+VE
Sbjct  13   RVAVVTGASSGIGAATARSLARDGYSVVLGARRVDRVDALAEEIGGRAMYLDVTDAASVE  72

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
                 L RVDVLVNNAGGAKGL  V++ADL+ WRWMW+TNV+GTLRVT+ALLP+L  SGD
Sbjct  73   RFVGTLDRVDVLVNNAGGAKGLAPVSEADLDDWRWMWETNVVGTLRVTKALLPELEASGD  132

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            GLI+T+TS AA+E YD GAGYT+AKHAQG LHRTLR EL+GKP+RLTEI PG VETEFSL
Sbjct  133  GLIITITSTAALEAYDNGAGYTSAKHAQGVLHRTLRLELIGKPIRLTEICPGMVETEFSL  192

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            VRF GD  +ADAVY G+TP+VA D+AE+I F A+RPSHVNLDQIV+RPRDQA++ R
Sbjct  193  VRFGGDAAKADAVYDGVTPMVAEDIAEIISFTASRPSHVNLDQIVVRPRDQATSRR  248


>gi|343925773|ref|ZP_08765288.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433]
 gi|343764124|dbj|GAA12214.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433]
Length=258

 Score =  342 bits (878),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 169/239 (71%), Positives = 197/239 (83%), Gaps = 0/239 (0%)

Query  7    RKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAA  66
            ++ +AVVTGASSGIG ATAR LA QG+HVV  ARR DR+ ALA +IGGT    DVTD+A+
Sbjct  16   QRPIAVVTGASSGIGAATARQLAKQGYHVVLGARRVDRVEALAAEIGGTGKQLDVTDEAS  75

Query  67   VEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDS  126
            V A    L RV VLVNNAGGAKGL  V++A+L+ WRWMW+TNVLG+LR+T+AL+P LI S
Sbjct  76   VAAFVEGLDRVHVLVNNAGGAKGLDPVSNANLDDWRWMWETNVLGSLRITKALIPALIAS  135

Query  127  GDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEF  186
            GDGLIV +TSIAA+E YD GAGYT+AKHAQ   HRTLR ELLG+PVRLTEI PG VET+F
Sbjct  136  GDGLIVAITSIAALEAYDNGAGYTSAKHAQAVTHRTLRYELLGQPVRLTEICPGMVETDF  195

Query  187  SLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRR  245
            SLVRF+GD+ RADAVY G+TPL A DVAEV+GFVA+RP HVNLDQIV+ PRDQASA R 
Sbjct  196  SLVRFEGDKDRADAVYQGLTPLTADDVAEVVGFVASRPPHVNLDQIVLMPRDQASARRN  254


>gi|262200802|ref|YP_003272010.1| short-chain dehydrogenase/reductase SDR [Gordonia bronchialis 
DSM 43247]
 gi|262084149|gb|ACY20117.1| short-chain dehydrogenase/reductase SDR [Gordonia bronchialis 
DSM 43247]
Length=259

 Score =  342 bits (877),  Expect = 3e-92, Method: Compositional matrix adjust.
 Identities = 171/240 (72%), Positives = 197/240 (83%), Gaps = 0/240 (0%)

Query  5    GTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDD  64
            G   ++AVVTGASSGIG ATAR LA QG+HVV  ARR DRI ALA +IGG     DVTD+
Sbjct  15   GASSKIAVVTGASSGIGAATARQLARQGYHVVLGARRVDRIKALAAEIGGDGRQLDVTDE  74

Query  65   AAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLI  124
             +V      L  V VLVNNAGGAKGL  VA+ADL+ WRWMW+TNVLG+LR+T+AL+P LI
Sbjct  75   ESVARFVDGLDTVHVLVNNAGGAKGLDPVANADLDDWRWMWETNVLGSLRITKALIPALI  134

Query  125  DSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVET  184
             SGDGLIV++TSIAA+E YD GAGYT+AKHAQ   HRTLR ELLGKPVRLTEIAPG VET
Sbjct  135  ASGDGLIVSITSIAALEAYDNGAGYTSAKHAQAVTHRTLRYELLGKPVRLTEIAPGMVET  194

Query  185  EFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            +FSLVRF+GD++RA+AVY G+TPL A DVAEVIGFVA+RP HVNLDQIV++PRDQASA R
Sbjct  195  DFSLVRFEGDKERANAVYEGLTPLTADDVAEVIGFVASRPPHVNLDQIVLKPRDQASARR  254


>gi|319950633|ref|ZP_08024538.1| oxidoreductase [Dietzia cinnamea P4]
 gi|319435708|gb|EFV90923.1| oxidoreductase [Dietzia cinnamea P4]
Length=259

 Score =  342 bits (877),  Expect = 3e-92, Method: Compositional matrix adjust.
 Identities = 167/236 (71%), Positives = 195/236 (83%), Gaps = 0/236 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            RVAVVTGASSGIGEATAR LA  GFHVV  ARR +R+ ALA++IGGTA+  DVTD  + E
Sbjct  20   RVAVVTGASSGIGEATARELARMGFHVVIGARRVERLQALADEIGGTAMPLDVTDADSCE  79

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            A   A+ R+ VLVNNAGGAKG   V DAD + WRWMW+TNVLGTLR+ R L+P L+++GD
Sbjct  80   AFCAAVPRLHVLVNNAGGAKGTTSVMDADEDQWRWMWETNVLGTLRMVRGLMPVLVETGD  139

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            GL+VT+TSIAAIE YD G+GYT+AKHAQ  LHRTLRGE LG+PVR TEIAPG VETEFS 
Sbjct  140  GLVVTITSIAAIESYDNGSGYTSAKHAQAVLHRTLRGEHLGQPVRFTEIAPGMVETEFSR  199

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            VRFDGD  +A AVY G+TP+VA DVAE++GFVA+RPSHVNLDQIV++PRDQ SA R
Sbjct  200  VRFDGDDDKAAAVYRGLTPMVAQDVAEIVGFVASRPSHVNLDQIVVKPRDQHSAMR  255


>gi|134103402|ref|YP_001109063.1| short chain dehydrogenase/reductase family oxidoreductase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|133916025|emb|CAM06138.1| oxidoreductase, short-chain dehydrogenase/reductase family [Saccharopolyspora 
erythraea NRRL 2338]
Length=248

 Score =  332 bits (850),  Expect = 4e-89, Method: Compositional matrix adjust.
 Identities = 167/236 (71%), Positives = 192/236 (82%), Gaps = 0/236 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            R AVVTGASSGIG ATAR LAA+GF VV  ARR +RI  LA++I G A+  D+TD A+VE
Sbjct  8    RWAVVTGASSGIGAATARKLAAEGFRVVLGARRVERINELASEIDGVAVALDITDPASVE  67

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            A    +   +VLVNNAGGAKGL  VADAD + WRWMW+TNVLGTLRVT+AL+PKL+ SGD
Sbjct  68   AFVERVETCNVLVNNAGGAKGLAKVADADEDDWRWMWETNVLGTLRVTKALMPKLVASGD  127

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            G +VTVTSIAA E+YD G+GYT+AKHAQGALHRTLRGE LG+PVR TEIAPG VETEFS 
Sbjct  128  GHVVTVTSIAATEIYDNGSGYTSAKHAQGALHRTLRGEHLGEPVRFTEIAPGMVETEFSE  187

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            VRF GD +RA AVY G+TPL A DVA+VI F  TRPSHVNLD I ++PRDQASA+R
Sbjct  188  VRFGGDAERAAAVYQGLTPLTADDVADVIAFAVTRPSHVNLDFIEMKPRDQASATR  243


>gi|333989113|ref|YP_004521727.1| short-chain dehydrogenase [Mycobacterium sp. JDM601]
 gi|333485080|gb|AEF34472.1| short-chain type oxidoreductase [Mycobacterium sp. JDM601]
Length=228

 Score =  329 bits (844),  Expect = 2e-88, Method: Compositional matrix adjust.
 Identities = 179/225 (80%), Positives = 197/225 (88%), Gaps = 8/225 (3%)

Query  35   VVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRV--------DVLVNNAGG  86
            ++AVARRADRITALA QIGGTA+VADV D AAV ALA    RV        +VLVNNAGG
Sbjct  1    MIAVARRADRITALAQQIGGTAVVADVADQAAVAALAEECDRVCDSLSGSINVLVNNAGG  60

Query  87   AKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGG  146
            A GL  V++ADLEHWRWMW+TNVLGTL+VTRALLPKLIDSGDGLIVTVTSIAA E+YDGG
Sbjct  61   ALGLAPVSEADLEHWRWMWETNVLGTLQVTRALLPKLIDSGDGLIVTVTSIAAFEIYDGG  120

Query  147  AGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMT  206
            AGYTAAKHAQ ALHRTLRGELLGKPVRLTEIAPG VETEFSLVRFDGD++RADAVYAG+T
Sbjct  121  AGYTAAKHAQSALHRTLRGELLGKPVRLTEIAPGMVETEFSLVRFDGDRERADAVYAGLT  180

Query  207  PLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR  251
            PL AAD+A+VIGFVA+RP HV+LDQIVIRPRDQASA+R+ T   R
Sbjct  181  PLTAADIADVIGFVASRPPHVDLDQIVIRPRDQASATRKVTRASR  225


>gi|291004379|ref|ZP_06562352.1| short chain dehydrogenase/reductase family oxidoreductase [Saccharopolyspora 
erythraea NRRL 2338]
Length=238

 Score =  329 bits (843),  Expect = 3e-88, Method: Compositional matrix adjust.
 Identities = 164/233 (71%), Positives = 190/233 (82%), Gaps = 0/233 (0%)

Query  12   VVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALA  71
            +VTGASSGIG ATAR LAA+GF VV  ARR +RI  LA++I G A+  D+TD A+VEA  
Sbjct  1    MVTGASSGIGAATARKLAAEGFRVVLGARRVERINELASEIDGVAVALDITDPASVEAFV  60

Query  72   RALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLI  131
              +   +VLVNNAGGAKGL  VADAD + WRWMW+TNVLGTLRVT+AL+PKL+ SGDG +
Sbjct  61   ERVETCNVLVNNAGGAKGLAKVADADEDDWRWMWETNVLGTLRVTKALMPKLVASGDGHV  120

Query  132  VTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRF  191
            VTVTSIAA E+YD G+GYT+AKHAQGALHRTLRGE LG+PVR TEIAPG VETEFS VRF
Sbjct  121  VTVTSIAATEIYDNGSGYTSAKHAQGALHRTLRGEHLGEPVRFTEIAPGMVETEFSEVRF  180

Query  192  DGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
             GD +RA AVY G+TPL A DVA+VI F  TRPSHVNLD I ++PRDQASA+R
Sbjct  181  GGDAERAAAVYQGLTPLTADDVADVIAFAVTRPSHVNLDFIEMKPRDQASATR  233


>gi|256380742|ref|YP_003104402.1| short-chain dehydrogenase/reductase SDR [Actinosynnema mirum 
DSM 43827]
 gi|255925045|gb|ACU40556.1| short-chain dehydrogenase/reductase SDR [Actinosynnema mirum 
DSM 43827]
Length=243

 Score =  319 bits (817),  Expect = 3e-85, Method: Compositional matrix adjust.
 Identities = 167/234 (72%), Positives = 194/234 (83%), Gaps = 0/234 (0%)

Query  11   AVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEAL  70
            AVVTGAS+GIGEATAR LAA+GFHVV  ARR + I ++A ++ GTAI  DVTD A+V AL
Sbjct  6    AVVTGASAGIGEATARRLAAEGFHVVLGARRLELIQSIAAEVDGTAIELDVTDAASVAAL  65

Query  71   ARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGL  130
            A A+  V VLVNNAGGA+GL  VA+AD E WRWMW+TNVLGTLRVT+ALLPKLI SGDG 
Sbjct  66   AEAVPEVRVLVNNAGGARGLSSVAEADEEQWRWMWETNVLGTLRVTKALLPKLIASGDGH  125

Query  131  IVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVR  190
            +VTVTSIAA E YD G+GYT+AKHAQ A+HRTLRGELLG+PVR+TE+ PG VET+FS+ R
Sbjct  126  VVTVTSIAAFEAYDNGSGYTSAKHAQSAVHRTLRGELLGEPVRVTEVLPGMVETDFSVNR  185

Query  191  FDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            FDGD +RA AVY G+TPL A DVA+ I F  TRPSHVNLD IV++PR QASASR
Sbjct  186  FDGDAERAAAVYRGLTPLTADDVADTIAFAVTRPSHVNLDTIVLKPRAQASASR  239


>gi|324999199|ref|ZP_08120311.1| short chain dehydrogenase/reductase family oxidoreductase [Pseudonocardia 
sp. P1]
Length=247

 Score =  306 bits (784),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 162/240 (68%), Positives = 188/240 (79%), Gaps = 0/240 (0%)

Query  6    TRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDA  65
            + +  AVVTGASSGIG ATAR LAA GFHVV  ARR +R   +A +I GTA+  DVTD  
Sbjct  4    SSRPTAVVTGASSGIGAATARGLAAAGFHVVLGARRVERCEEIAKEIDGTALPLDVTDAG  63

Query  66   AVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLID  125
            +V A   A+    +LVNNAGGAKGL  VA+AD + WRWMW+TNVLGTLR+T+A LPKL  
Sbjct  64   SVAAFDAAVPEAKLLVNNAGGAKGLDPVAEADEDDWRWMWETNVLGTLRLTKAFLPKLEA  123

Query  126  SGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETE  185
            SGDG +VTVTSIAA++ YD GAGYT AKHAQ  LHRTLRGELLGKP+R+TEI PG VETE
Sbjct  124  SGDGHVVTVTSIAALDFYDNGAGYTGAKHAQAMLHRTLRGELLGKPIRITEICPGMVETE  183

Query  186  FSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRR  245
            FS VRFDGD ++A  VY G+TPL A DVAE I F ATRP+HVN+DQIV++PRDQAS SRR
Sbjct  184  FSEVRFDGDAEKAAKVYQGLTPLSADDVAETITFAATRPAHVNIDQIVLKPRDQASGSRR  243


>gi|331694477|ref|YP_004330716.1| Serine 3-dehydrogenase [Pseudonocardia dioxanivorans CB1190]
 gi|326949166|gb|AEA22863.1| Serine 3-dehydrogenase [Pseudonocardia dioxanivorans CB1190]
Length=248

 Score =  303 bits (777),  Expect = 1e-80, Method: Compositional matrix adjust.
 Identities = 166/244 (69%), Positives = 187/244 (77%), Gaps = 1/244 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MT+   R   AVVTGASSGIG ATAR LA  GFHVV  ARR DR   +A +I GTA+  D
Sbjct  1    MTSPSDRP-TAVVTGASSGIGAATARALAGAGFHVVLGARRVDRCAEIAREIDGTAVRLD  59

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTD  +V A   A+    +LVNNAGGAKGL+ VADAD + WRWMW+ NVLGTLR+ + LL
Sbjct  60   VTDPESVSAFVAAVPECRLLVNNAGGAKGLEPVADADEDAWRWMWEANVLGTLRMVKGLL  119

Query  121  PKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG  180
            P L+ SGDG IVTVTSIAA+E YD GAGYT AKHAQ  LHRTLRGELLG+PVRLTEIAPG
Sbjct  120  PALVASGDGHIVTVTSIAALEPYDNGAGYTGAKHAQAMLHRTLRGELLGQPVRLTEIAPG  179

Query  181  AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA  240
             VETEFSLVRF GD ++AD VY G+TPL A DVAE I F ATRPSHVN+D IV++PR QA
Sbjct  180  MVETEFSLVRFAGDAEKADNVYRGLTPLTAEDVAETIVFAATRPSHVNIDLIVLKPRAQA  239

Query  241  SASR  244
            SA R
Sbjct  240  SAMR  243


>gi|257054340|ref|YP_003132172.1| short-chain alcohol dehydrogenase [Saccharomonospora viridis 
DSM 43017]
 gi|256584212|gb|ACU95345.1| short-chain alcohol dehydrogenase [Saccharomonospora viridis 
DSM 43017]
Length=243

 Score =  302 bits (774),  Expect = 2e-80, Method: Compositional matrix adjust.
 Identities = 157/236 (67%), Positives = 181/236 (77%), Gaps = 0/236 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            R AV+TGAS+GIG ATAR LA  GFHVV  ARR +++  LA ++ GTA   DVTD  +V 
Sbjct  4    RTAVITGASAGIGAATARALANAGFHVVLGARRLEKLQPLAEELSGTAYQLDVTDADSVA  63

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            +    +    VLVNNAGGA+GL  V  AD E WRWMW+TNVLGTLR+T+ALLPKL+ SGD
Sbjct  64   SFVDRIPECHVLVNNAGGARGLDRVEHADEERWRWMWETNVLGTLRITKALLPKLLASGD  123

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
            G ++TVTSIA  EVYDGGAGYT+AKHAQ ALHRTLR E LG P+RLTEI PG VETEFS+
Sbjct  124  GHVITVTSIAGHEVYDGGAGYTSAKHAQSALHRTLRSEHLGDPLRLTEIIPGMVETEFSI  183

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
             RFDGD +RA  VY G+TPL A DVAEVI F ATRP HVNLDQIV++PR Q S SR
Sbjct  184  NRFDGDTERAAKVYEGVTPLTAEDVAEVIAFAATRPPHVNLDQIVLKPRAQYSGSR  239


>gi|296394474|ref|YP_003659358.1| short-chain dehydrogenase/reductase SDR [Segniliparus rotundus 
DSM 44985]
 gi|296181621|gb|ADG98527.1| short-chain dehydrogenase/reductase SDR [Segniliparus rotundus 
DSM 44985]
Length=249

 Score =  300 bits (768),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 157/241 (66%), Positives = 184/241 (77%), Gaps = 0/241 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            R AVVTGASSGIG ATA TLA  GF VV  ARR D++ ALA ++GG A+  DVTD A+V+
Sbjct  3    RTAVVTGASSGIGAATASTLAEAGFEVVLGARRLDKLDALAKRLGGRALPLDVTDQASVD  62

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
            A A  L  VDVLVNNAGGA GL  VADA ++ WR   + NV GTLRVT+ALLP L  S D
Sbjct  63   AFAAQLGGVDVLVNNAGGAFGLSSVADASVDEWRQNIEVNVFGTLRVTKALLPLLRASDD  122

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
             +IVTVTSIAA  VY GG+ YTAAKHAQ ALHRTLR EL G+P+R++E+ PGAV TEFSL
Sbjct  123  AMIVTVTSIAADTVYTGGSAYTAAKHAQSALHRTLRLELKGEPIRISEVKPGAVNTEFSL  182

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRATH  248
            VRF GDQ RADAVY G+TPLVA DVAEVIGF+ATRP+HVN+D I ++PR Q   +++   
Sbjct  183  VRFGGDQARADAVYDGITPLVAQDVAEVIGFIATRPAHVNIDSITVKPRSQYEGAQQFRA  242

Query  249  P  249
            P
Sbjct  243  P  243


>gi|317508248|ref|ZP_07965928.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974]
 gi|316253423|gb|EFV12813.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974]
Length=245

 Score =  297 bits (760),  Expect = 1e-78, Method: Compositional matrix adjust.
 Identities = 156/242 (65%), Positives = 184/242 (77%), Gaps = 0/242 (0%)

Query  8    KRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAV  67
            +R+AVVTGASSGIGEATA TLA  GF VV  ARR DR+  LA +IG  A+  DVTD A+V
Sbjct  2    RRIAVVTGASSGIGEATAVTLAEAGFDVVLGARRLDRLADLAERIGARALPLDVTDQASV  61

Query  68   EALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSG  127
            +A A  L   DVLVNNAGGA GL  +A+A ++ WR   + NV GTLRVT+ALLP L  S 
Sbjct  62   DAFAAQLPSADVLVNNAGGAFGLSPLAEASVDEWRANIEVNVFGTLRVTKALLPLLRASD  121

Query  128  DGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFS  187
            D LIVTVTSIAA  VY GG+ YTAAKHAQ ALHRTLR EL G+P+R++E+ PGAV TEFS
Sbjct  122  DALIVTVTSIAADTVYTGGSAYTAAKHAQSALHRTLRLELKGEPIRISEVKPGAVNTEFS  181

Query  188  LVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRAT  247
            LVRF GDQ RADAVY G+TPLVA DVA+VIGF+ATRP+HVN+D I I+PR Q   +++  
Sbjct  182  LVRFGGDQARADAVYEGITPLVAQDVADVIGFIATRPAHVNIDSITIKPRSQYEGAQQFR  241

Query  248  HP  249
             P
Sbjct  242  AP  243


>gi|296268482|ref|YP_003651114.1| short-chain dehydrogenase/reductase SDR [Thermobispora bispora 
DSM 43833]
 gi|296091269|gb|ADG87221.1| short-chain dehydrogenase/reductase SDR [Thermobispora bispora 
DSM 43833]
Length=250

 Score =  273 bits (698),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 144/240 (60%), Positives = 179/240 (75%), Gaps = 3/240 (1%)

Query  8    KRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGT-AIVADVTDDAA  66
            K+ AVVTGASSGIG ATAR LAA+G+ VVA ARR DR+  LA ++ G   +  DVT   +
Sbjct  3    KKTAVVTGASSGIGAATARRLAAEGYQVVAGARRRDRLEKLAAEVDGIIPVTLDVTSQES  62

Query  67   VEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDS  126
            V+ALA +L R DVLVNNAGGA GL+ VA+  +E W+ M+D NVLGT R+TRALLPKLI+S
Sbjct  63   VDALAASLDRCDVLVNNAGGAIGLEPVAEGSVEDWQRMYDVNVLGTFRMTRALLPKLIES  122

Query  127  GDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVET-E  185
            GDG++V VTS+A    Y+GG GY AAKHAQ ++  TLR EL G+PVR+ E+APG V+T E
Sbjct  123  GDGVLVLVTSVAGHVSYEGGGGYCAAKHAQASMAATLRLELCGRPVRVIEVAPGMVKTEE  182

Query  186  FSLVRFDGDQQRADAVYAGMT-PLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
            FSL RF GD +RA  VY G+  PL A D+A+VI F  TRP HVN+DQIV+RPR QA+  +
Sbjct  183  FSLTRFRGDAERAAKVYEGVPDPLTADDIADVIAFAVTRPPHVNIDQIVVRPRAQAAQHK  242


>gi|237784840|ref|YP_002905545.1| putative oxidoreductase [Corynebacterium kroppenstedtii DSM 44385]
 gi|237757752|gb|ACR17002.1| putative oxidoreductase [Corynebacterium kroppenstedtii DSM 44385]
Length=266

 Score =  265 bits (676),  Expect = 6e-69, Method: Compositional matrix adjust.
 Identities = 136/237 (58%), Positives = 173/237 (73%), Gaps = 0/237 (0%)

Query  8    KRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAV  67
            K VAV+TGASSGIG A+A+ LA  G+ V   ARR +++ A+A  I   A+  DVTD  +V
Sbjct  24   KPVAVITGASSGIGAASAKALADAGYTVYIGARRVEKLQAVAEGIDAVALPLDVTDQESV  83

Query  68   EALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSG  127
            +     + R DVLVNNAGGA G + +ADA++E W+WM+DTNVLGTLRVTRALLPK+  SG
Sbjct  84   DKFCEQVPRCDVLVNNAGGAHGSESIADANVEDWQWMYDTNVLGTLRVTRALLPKVEASG  143

Query  128  DGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFS  187
            DG ++ ++SIA  E Y GGAGY AAKHA  A+ R LR ELLGKPVR+ EI PG V TEFS
Sbjct  144  DGQVINISSIAGHEPYRGGAGYNAAKHAVAAMTRVLRLELLGKPVRVCEICPGLVNTEFS  203

Query  188  LVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASR  244
             VRF GD+++ADAVY G+ P+VA D+A+ + ++ATRPS +N+D I I  RDQ SA  
Sbjct  204  TVRFGGDKEKADAVYRGLEPMVAEDIADAVVWIATRPSRMNIDHITIMARDQVSAQE  260


>gi|339293532|gb|AEJ45643.1| hypothetical protein CCDC5079_0453 [Mycobacterium tuberculosis 
CCDC5079]
Length=205

 Score =  263 bits (673),  Expect = 1e-68, Method: Compositional matrix adjust.
 Identities = 136/136 (100%), Positives = 136/136 (100%), Gaps = 0/136 (0%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
Sbjct  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60

Query  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120
            VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
Sbjct  61   VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL  120

Query  121  PKLIDSGDGLIVTVTS  136
            PKLIDSGDGLIVTVTS
Sbjct  121  PKLIDSGDGLIVTVTS  136


>gi|269124955|ref|YP_003298325.1| short-chain dehydrogenase/reductase SDR [Thermomonospora curvata 
DSM 43183]
 gi|268309913|gb|ACY96287.1| short-chain dehydrogenase/reductase SDR [Thermomonospora curvata 
DSM 43183]
Length=255

 Score =  263 bits (671),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 146/251 (59%), Positives = 181/251 (73%), Gaps = 10/251 (3%)

Query  4    IGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGT--------  55
            +G  ++ AVVTGASSGIG ATAR LAA+GF+VV  ARR +R+ AL  QIG          
Sbjct  1    MGGVRKTAVVTGASSGIGAATARRLAAEGFNVVLAARRRERLDALVEQIGKEVPGAGRLA  60

Query  56   AIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRV  115
            A+  DVT   +V+ALA  L    VLVNNAGGA G++ VA+AD E WR M+DTNVLG LRV
Sbjct  61   AVTLDVTSQDSVDALAAGLPACHVLVNNAGGAIGMEPVAEADPEDWRVMYDTNVLGLLRV  120

Query  116  TRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLT  175
            T+ALLPKLIDSGDG +V +TS+A    Y+GGAGY AAKHA  A++  +R EL+ KPVR+T
Sbjct  121  TKALLPKLIDSGDGHVVNITSLAGHVPYEGGAGYNAAKHAAVAVNEVMRLELVDKPVRVT  180

Query  176  EIAPGAVET-EFSLVRFDGDQQRADAVYAGMT-PLVAADVAEVIGFVATRPSHVNLDQIV  233
            EIAPG V T EFSLVRF GD +RA  VY G+  PLVA DVA+ + +  TRPSHVN+D+I 
Sbjct  181  EIAPGMVHTEEFSLVRFRGDAERAAKVYEGVPEPLVAEDVADCVAWAVTRPSHVNIDRID  240

Query  234  IRPRDQASASR  244
            ++PR QA+  +
Sbjct  241  VQPRVQATPYK  251


>gi|227487396|ref|ZP_03917712.1| serine 3-dehydrogenase [Corynebacterium glucuronolyticum ATCC 
51867]
 gi|227092620|gb|EEI27932.1| serine 3-dehydrogenase [Corynebacterium glucuronolyticum ATCC 
51867]
Length=231

 Score =  263 bits (671),  Expect = 2e-68, Method: Compositional matrix adjust.
 Identities = 134/231 (59%), Positives = 172/231 (75%), Gaps = 2/231 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            + A+VTG SSGIG ATAR LA  G+HV+  ARR DR+ A+A +IGG AI  DVTD+ +V 
Sbjct  2    KTALVTGGSSGIGAATARALAKDGWHVIVAARRKDRLQAVAEEIGGEAIALDVTDEDSVA  61

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
             L   +  +D+LVNNAGGAKGL  V +A+++ W+WM++TNVLGT+RVT+ALLPKL+D   
Sbjct  62   RLVEQIDSLDLLVNNAGGAKGLDSVEEANIDDWKWMYETNVLGTVRVTKALLPKLVDGAQ  121

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
              IV V SIA I  Y GGAGY AAK    AL R LR E L +P+R+ EI PG V+T+FSL
Sbjct  122  --IVNVGSIAGITPYVGGAGYNAAKFGVAALTRVLRLETLDRPLRVCEINPGRVKTDFSL  179

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQ  239
            +RF GD++RADAVYAG   LVA D+AE I +VA+ P+HVN+D++VI+P DQ
Sbjct  180  IRFKGDKERADAVYAGHQNLVAEDIAEAIRWVASLPAHVNIDRLVIKPADQ  230


>gi|271962506|ref|YP_003336702.1| short-chain alcohol dehydrogenase [Streptosporangium roseum DSM 
43021]
 gi|270505681|gb|ACZ83959.1| short-chain alcohol dehydrogenase of unknown specificity [Streptosporangium 
roseum DSM 43021]
Length=245

 Score =  263 bits (671),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 139/237 (59%), Positives = 176/237 (75%), Gaps = 3/237 (1%)

Query  8    KRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGT-AIVADVTDDAA  66
             R AVVTGASSGIGEATAR LAA+GF VVA ARR DR+  LA ++ G  A+  DVT   +
Sbjct  2    NRTAVVTGASSGIGEATARRLAAEGFDVVAAARRRDRLDKLAAEVPGIRAVTLDVTSQES  61

Query  67   VEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDS  126
            V+ LA +L R DVLVNNAGGA GL+ VA  D+  W+ M+D NVLG+LRVT+ALLP+L++S
Sbjct  62   VDELAASLDRCDVLVNNAGGAVGLEPVASGDVADWQKMYDINVLGSLRVTQALLPRLVES  121

Query  127  GDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVET-E  185
            GDG++V +TS+A +  Y+GG GY AAKHAQ ++   LR EL G+PVR+ EIAPG V T E
Sbjct  122  GDGVLVMLTSVAGLVSYEGGGGYNAAKHAQSSMAEVLRLELCGEPVRIIEIAPGMVHTEE  181

Query  186  FSLVRFDGDQQRADAVYAGMT-PLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQAS  241
            F+L RF GD   AD VY G+  PL A DVA+ + +  TRP+HVN+D++VIRPR QA+
Sbjct  182  FALNRFRGDSSAADRVYEGVPGPLSADDVADAVSWCVTRPAHVNIDRLVIRPRAQAA  238


>gi|227541140|ref|ZP_03971189.1| serine 3-dehydrogenase [Corynebacterium glucuronolyticum ATCC 
51866]
 gi|227183100|gb|EEI64072.1| serine 3-dehydrogenase [Corynebacterium glucuronolyticum ATCC 
51866]
Length=231

 Score =  262 bits (670),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 133/231 (58%), Positives = 172/231 (75%), Gaps = 2/231 (0%)

Query  9    RVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVE  68
            + A+VTG SSGIG ATAR LA  G+HV+  ARR D++ A+A +IGG AI  DVTD+ +V 
Sbjct  2    KTALVTGGSSGIGAATARALAKDGWHVIVAARRKDKLQAVAEEIGGEAIALDVTDEDSVA  61

Query  69   ALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD  128
             L   +  +D+LVNNAGGAKGL  V +A+++ W+WM++TNVLGT+RVT+ALLPKL+D   
Sbjct  62   RLVEQIDSLDLLVNNAGGAKGLDSVEEANIDDWKWMYETNVLGTVRVTKALLPKLVDGAQ  121

Query  129  GLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSL  188
              IV V SIA I  Y GGAGY AAK    AL R LR E L +P+R+ EI PG V+T+FSL
Sbjct  122  --IVNVGSIAGITPYVGGAGYNAAKFGVAALTRVLRLETLDRPLRVCEINPGRVKTDFSL  179

Query  189  VRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQ  239
            +RF GD++RADAVYAG   LVA D+AE I +VA+ P+HVN+D++VI+P DQ
Sbjct  180  IRFKGDKERADAVYAGHQNLVAEDIAEAIRWVASLPAHVNIDRLVIKPADQ  230


>gi|332669978|ref|YP_004452986.1| short-chain dehydrogenase/reductase SDR [Cellulomonas fimi ATCC 
484]
 gi|332339016|gb|AEE45599.1| short-chain dehydrogenase/reductase SDR [Cellulomonas fimi ATCC 
484]
Length=254

 Score =  262 bits (669),  Expect = 4e-68, Method: Compositional matrix adjust.
 Identities = 151/250 (61%), Positives = 176/250 (71%), Gaps = 4/250 (1%)

Query  1    MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD  60
            M+T   R R AVVTGASSGIG AT R L  +G+ VVA ARRADR+ ALA + G  A VAD
Sbjct  1    MSTAPARTRRAVVTGASSGIGAATVRRLRVEGWDVVATARRADRLEALAAETGAQAFVAD  60

Query  61   VTDDAAVEALAR---ALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTR  117
            VT D  V  LA    A   VD LVNNAGGA GL  V  ADLE WR M+D NVLGTLRVT+
Sbjct  61   VTSDDDVARLAAHVAATGGVDALVNNAGGALGLDPVETADLEQWRTMYDLNVLGTLRVTK  120

Query  118  ALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEI  177
            A LP L + G+G +V VTS AA   Y+GGAGYT AKHA+  L  TLR E++G+P+R+ EI
Sbjct  121  AFLPLLRERGEGDVVVVTSTAAHGAYEGGAGYTGAKHAERMLATTLRWEIVGEPIRVVEI  180

Query  178  APGAVET-EFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRP  236
            APGAV T EFSLVRFDGD +RA AVY G  PLVA DVA+ I +  TRP HVN+D +V+RP
Sbjct  181  APGAVATEEFSLVRFDGDAERAAAVYEGYLPLVADDVADAITWALTRPPHVNVDLLVVRP  240

Query  237  RDQASASRRA  246
            R QA  ++ A
Sbjct  241  RAQAHNTKTA  250



Lambda     K      H
   0.320    0.133    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 362093846100




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40