BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv0490 Length=410 Score E Sequences producing significant alignments: (Bits) Value gi|15607631|ref|NP_215004.1| putative two component sensor histi... 815 0.0 gi|254363454|ref|ZP_04979500.1| two component sensor histidine k... 814 0.0 gi|289573077|ref|ZP_06453304.1| two component system sensor hist... 813 0.0 gi|121636406|ref|YP_976629.1| putative two component sensor hist... 812 0.0 gi|289752522|ref|ZP_06511900.1| sensor histidine kinase SenX3 [M... 812 0.0 gi|167970686|ref|ZP_02552963.1| two component system sensor hist... 812 0.0 gi|289568410|ref|ZP_06448637.1| sensor-like histidine kinase [My... 796 0.0 gi|240169872|ref|ZP_04748531.1| two-component sensor histidine k... 646 0.0 gi|118465980|ref|YP_883790.1| hisitidine protein kinase SenX3 [M... 645 0.0 gi|1731204|sp|P54883.1|SEX3_MYCLE RecName: Full=Sensor-like hist... 645 0.0 gi|41410080|ref|NP_962916.1| SenX3 [Mycobacterium avium subsp. p... 645 0.0 gi|15828318|ref|NP_302581.1| two-component system sensor histidi... 642 0.0 gi|254777098|ref|ZP_05218614.1| hisitidine protein kinase SenX3 ... 640 0.0 gi|296168091|ref|ZP_06850157.1| sensor histidine kinase [Mycobac... 628 6e-178 gi|254821075|ref|ZP_05226076.1| SenX3 [Mycobacterium intracellul... 621 8e-176 gi|342859009|ref|ZP_08715663.1| SenX3 [Mycobacterium colombiense... 617 1e-174 gi|183980839|ref|YP_001849130.1| two-component sensor histidine ... 598 4e-169 gi|118619652|ref|YP_907984.1| two component sensor histidine kin... 596 2e-168 gi|120401845|ref|YP_951674.1| histidine kinase [Mycobacterium va... 543 2e-152 gi|289756565|ref|ZP_06515943.1| predicted protein [Mycobacterium... 536 2e-150 gi|126433264|ref|YP_001068955.1| histidine kinase [Mycobacterium... 506 2e-141 gi|118471880|ref|YP_885339.1| sensor histidine kinase SenX3 [Myc... 505 4e-141 gi|108797640|ref|YP_637837.1| histidine kinase [Mycobacterium sp... 504 7e-141 gi|9964000|gb|AAG09796.1|AF258346_1 hisitidine protein kinase Se... 499 5e-139 gi|315442359|ref|YP_004075238.1| histidine kinase [Mycobacterium... 493 2e-137 gi|333989118|ref|YP_004521732.1| two-component sensor histidine ... 491 7e-137 gi|145220689|ref|YP_001131367.1| histidine kinase [Mycobacterium... 487 1e-135 gi|169631127|ref|YP_001704776.1| sensor-like histidine kinase se... 461 8e-128 gi|312141111|ref|YP_004008447.1| two component system sensor kin... 426 4e-117 gi|111019062|ref|YP_702034.1| sensor kinase, two-component syste... 423 2e-116 gi|54027161|ref|YP_121403.1| putative two-component system senso... 422 7e-116 gi|226361155|ref|YP_002778933.1| two-component histidine kinase ... 421 1e-115 gi|229490606|ref|ZP_04384444.1| His Kinase A domain protein [Rho... 421 1e-115 gi|226305110|ref|YP_002765068.1| two-component histidine kinase ... 420 2e-115 gi|333918301|ref|YP_004491882.1| sensor histidine kinase [Amycol... 407 2e-111 gi|134103392|ref|YP_001109053.1| putative two-component system s... 366 4e-99 gi|296138386|ref|YP_003645629.1| histidine kinase [Tsukamurella ... 365 1e-98 gi|336460429|gb|EGO39326.1| histidine kinase [Mycobacterium aviu... 364 2e-98 gi|319949622|ref|ZP_08023662.1| two component system sensor kina... 358 1e-96 gi|62389303|ref|YP_224705.1| two component sensor kinase [Coryne... 355 6e-96 gi|19551648|ref|NP_599650.1| signal transduction histidine kinas... 353 4e-95 gi|300782392|ref|YP_003762683.1| two-component system histidine ... 351 2e-94 gi|257054345|ref|YP_003132177.1| histidine kinase [Saccharomonos... 349 4e-94 gi|289748981|ref|ZP_06508359.1| LOW QUALITY PROTEIN: two compone... 348 8e-94 gi|334563886|ref|ZP_08516877.1| two-component system sensor kina... 347 2e-93 gi|302523819|ref|ZP_07276161.1| phosphate regulon sensor kinase ... 347 2e-93 gi|25026980|ref|NP_737034.1| putative sensor kinase [Corynebacte... 344 1e-92 gi|336326509|ref|YP_004606475.1| two-component system sensor his... 343 2e-92 gi|260579349|ref|ZP_05847231.1| sensor histidine kinase [Coryneb... 340 3e-91 gi|227541628|ref|ZP_03971677.1| histidine kinase [Corynebacteriu... 339 4e-91 >gi|15607631|ref|NP_215004.1| putative two component sensor histidine kinase SENX3 [Mycobacterium tuberculosis H37Rv] gi|15839881|ref|NP_334918.1| sensor histidine kinase SenX3 [Mycobacterium tuberculosis CDC1551] gi|31791670|ref|NP_854163.1| putative two component sensor histidine kinase SENX3 [Mycobacterium bovis AF2122/97] 61 more sequence titles Length=410 Score = 815 bits (2104), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/410 (99%), Positives = 410/410 (100%), Gaps = 0/410 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP Sbjct 1 MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG Sbjct 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE Sbjct 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR Sbjct 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI Sbjct 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR Sbjct 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 >gi|254363454|ref|ZP_04979500.1| two component sensor histidine kinase senX3 [Mycobacterium tuberculosis str. Haarlem] gi|134148968|gb|EBA41013.1| two component sensor histidine kinase senX3 [Mycobacterium tuberculosis str. Haarlem] Length=410 Score = 814 bits (2102), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/410 (99%), Positives = 410/410 (100%), Gaps = 0/410 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQ+VATEWSGITVSQMLQCIVTLMP Sbjct 1 MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQQVATEWSGITVSQMLQCIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG Sbjct 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE Sbjct 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR Sbjct 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI Sbjct 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR Sbjct 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 >gi|289573077|ref|ZP_06453304.1| two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis K85] gi|339630560|ref|YP_004722202.1| two component sensor histidine kinase [Mycobacterium africanum GM041182] gi|289537508|gb|EFD42086.1| two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis K85] gi|339329916|emb|CCC25566.1| putative two component sensor histidine kinase SENX3 [Mycobacterium africanum GM041182] Length=409 Score = 813 bits (2101), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP Sbjct 1 MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG Sbjct 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE Sbjct 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR Sbjct 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI Sbjct 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELS 409 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELS Sbjct 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELS 409 >gi|121636406|ref|YP_976629.1| putative two component sensor histidine kinase senX3 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224988878|ref|YP_002643565.1| putative two component sensor histidine kinase [Mycobacterium bovis BCG str. Tokyo 172] gi|2190434|emb|CAA73954.1| SenX3 [Mycobacterium bovis BCG] gi|121492053|emb|CAL70516.1| Putative two component sensor histidine kinase senX3 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224771991|dbj|BAH24797.1| putative two component sensor histidine kinase [Mycobacterium bovis BCG str. Tokyo 172] gi|341600422|emb|CCC63092.1| putative two component sensor histidine kinase senX3 [Mycobacterium bovis BCG str. Moreau RDJ] Length=410 Score = 812 bits (2098), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/410 (99%), Positives = 409/410 (99%), Gaps = 0/410 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP Sbjct 1 MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVE DLSPRKRSATG Sbjct 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVESDLSPRKRSATG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE Sbjct 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR Sbjct 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI Sbjct 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR Sbjct 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 >gi|289752522|ref|ZP_06511900.1| sensor histidine kinase SenX3 [Mycobacterium tuberculosis EAS054] gi|289693109|gb|EFD60538.1| sensor histidine kinase SenX3 [Mycobacterium tuberculosis EAS054] Length=410 Score = 812 bits (2098), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/410 (99%), Positives = 409/410 (99%), Gaps = 0/410 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP Sbjct 1 MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG Sbjct 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE Sbjct 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRR Sbjct 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRC 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI Sbjct 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR Sbjct 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 >gi|167970686|ref|ZP_02552963.1| two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis H37Ra] gi|308372904|ref|ZP_07430349.2| two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis SUMu005] gi|308339439|gb|EFP28290.1| two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis SUMu005] Length=408 Score = 812 bits (2097), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/408 (99%), Positives = 408/408 (100%), Gaps = 0/408 (0%) Query 3 VFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 62 +FSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG Sbjct 1 MFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 60 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 122 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS Sbjct 61 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 120 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA Sbjct 121 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 180 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI Sbjct 181 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 240 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG Sbjct 241 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 300 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV Sbjct 301 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 360 Query 363 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR Sbjct 361 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 408 >gi|289568410|ref|ZP_06448637.1| sensor-like histidine kinase [Mycobacterium tuberculosis T17] gi|289542163|gb|EFD45812.1| sensor-like histidine kinase [Mycobacterium tuberculosis T17] Length=408 Score = 796 bits (2056), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/408 (99%), Positives = 404/408 (99%), Gaps = 0/408 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP Sbjct 1 MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG Sbjct 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE Sbjct 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNADIEVRT APSNLRVLGDQT+LVTALANLVSNAIAYSPRGSLVSISRR Sbjct 241 AISRHKVAADNADIEVRTVAPSNLRVLGDQTVLVTALANLVSNAIAYSPRGSLVSISRRC 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RGA IEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAAN DGTI Sbjct 301 RGAIIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANLDGTI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEEL 408 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEEL Sbjct 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEEL 408 >gi|240169872|ref|ZP_04748531.1| two-component sensor histidine kinase SenX3 [Mycobacterium kansasii ATCC 12478] Length=406 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/409 (86%), Positives = 369/409 (91%), Gaps = 3/409 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLS LALAVG A G RL+ RV +RQ+ ATE +GITV+QMLQ IV LMP Sbjct 1 MTVFSALLLAGVLSVLALAVGVAAGNRLSQRVARRRQQAATERAGITVAQMLQRIVALMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 +GAAVVD HRDVVYLN RA+ELGLVRDRQLDDQAWRAA+QALGG+DVEFDLSP KR+A G Sbjct 61 MGAAVVDAHRDVVYLNHRARELGLVRDRQLDDQAWRAAQQALGGDDVEFDLSPAKRAA-G 119 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGL VHGHARLLSEEDRRF VVFVHDQSDYARMEA RRDFVANVSHELKTPVGAMALLA Sbjct 120 RSGLLVHGHARLLSEEDRRFVVVFVHDQSDYARMEATRRDFVANVSHELKTPVGAMALLA 179 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLAS DDS+TVRRFAEKVLIEANRLGDMVAELIELSRLQGAE L N+TDVDVDTIVSE Sbjct 180 EALLASPDDSDTVRRFAEKVLIEANRLGDMVAELIELSRLQGAEGLHNVTDVDVDTIVSE 239 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAAD ADIEVRTDAPS LRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR Sbjct 240 AISRHKVAADTADIEVRTDAPSGLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 299 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RG N+EIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I Sbjct 300 RGDNVEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSI 359 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELS 409 VWSKPGTGSTFTL++PA + E +Q R + R NRSQREEELS Sbjct 360 GVWSKPGTGSTFTLSIPA--AECDESELSDQLRARDARPNRSQREEELS 406 >gi|118465980|ref|YP_883790.1| hisitidine protein kinase SenX3 [Mycobacterium avium 104] gi|118167267|gb|ABK68164.1| hisitidine protein kinase SenX3 [Mycobacterium avium 104] Length=407 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/408 (85%), Positives = 370/408 (91%), Gaps = 1/408 (0%) Query 3 VFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 62 +FSALLLAGVLS LALA G AVG RL+ R ++RQR++TEW+GITV+QML+ IV LMPLG Sbjct 1 MFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMPLG 60 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 122 AAVVD HRDVVYLN+RAKELGLVRDRQLDDQAW AA+QAL G DVEFDL P KRS GRS Sbjct 61 AAVVDAHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSG-GRS 119 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 GLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLAEA Sbjct 120 GLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAEA 179 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 LLASADDSETVRRFAEKVL+EANRLGDMVAELIELSRLQGAERL N+T+VDVD++V+EAI Sbjct 180 LLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVDVDSVVNEAI 239 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 SRHKVAADNA+IEVRTDAPS LRVLGD+TLLVTALANLVSNAIAYSP GS VSISRRRRG Sbjct 240 SRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRG 299 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 NIEIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+GTI V Sbjct 300 DNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIGV 359 Query 363 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 WSKPGTGSTFTL++PA + ++ D EQ + E+R NRSQREEELSR Sbjct 360 WSKPGTGSTFTLSIPAAVASHRGDGESEQPQGREVRPNRSQREEELSR 407 >gi|1731204|sp|P54883.1|SEX3_MYCLE RecName: Full=Sensor-like histidine kinase senX3 gi|467057|gb|AAA17241.1| phoR [Mycobacterium leprae] Length=443 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/408 (84%), Positives = 368/408 (91%), Gaps = 1/408 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLS LA VG G+RL+ R++E+RQR+A EW+GITV QMLQ I+ LMP Sbjct 1 MTVFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVDT+RDVVYLNE+AKELGLVRDRQLDDQAWRAA+QALGG+DVEFDL P KR A G Sbjct 61 LGAAVVDTYRDVVYLNEQAKELGLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAG 120 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHGHARLLSE+DRRFAVVFVHDQSDY RMEAARRDFVANVSHELKTPVGAMALLA Sbjct 121 RSGLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFVANVSHELKTPVGAMALLA 180 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADD+ETV RFAEKVLIEANRLG MVAELIELSRLQGAERLPN+TD+DVD IVSE Sbjct 181 EALLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSE 240 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AI+RHKVAAD A IEVRTD PS LRVLGDQTLLVTALANLVSNAIAYSP GSLVSISRRR Sbjct 241 AIARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRR 300 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RG NIEIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I Sbjct 301 RGDNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSI 360 Query 361 RVWSKPGTGSTFTLALPALIEAYHD-DERPEQAREPELRSNRSQREEE 407 VWSKPGTGSTFTL++PA + Y D DE+ Q R ++ NR QREEE Sbjct 361 GVWSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNRPQREEE 408 >gi|41410080|ref|NP_962916.1| SenX3 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398913|gb|AAS06532.1| SenX3 [Mycobacterium avium subsp. paratuberculosis K-10] Length=409 Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/410 (84%), Positives = 372/410 (91%), Gaps = 1/410 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLS LALA G AVG RL+ R ++RQR++TEW+GITV+QML+ IV LMP Sbjct 1 MTVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVD HRDVVYLN+RAKELGLVRDRQLDDQAW AA+QAL G DVEFDL P KRS G Sbjct 61 LGAAVVDAHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSG-G 119 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 R+GLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLA Sbjct 120 RAGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLA 179 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDSETVRRFAEKVL+EANRLGDMVAELIELSRLQGAERL N+T+V+VD++V+E Sbjct 180 EALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSVVNE 239 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNA+IEVRTDAPS LRVLGD+TLLVTALANLVSNAIAYSP GS VSISRRR Sbjct 240 AISRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRR 299 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RG NIEIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+GTI Sbjct 300 RGDNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTI 359 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 VWSKPGTGSTFTL++PA + ++ D EQ + ++R NRSQREEELSR Sbjct 360 GVWSKPGTGSTFTLSIPAAVASHRGDGESEQPQGRDVRPNRSQREEELSR 409 >gi|15828318|ref|NP_302581.1| two-component system sensor histidine kinase [Mycobacterium leprae TN] gi|221230795|ref|YP_002504211.1| putative two-component system sensor histidine kinase [Mycobacterium leprae Br4923] gi|13094011|emb|CAC31957.1| probable two-component system sensor histidine kinase [Mycobacterium leprae] gi|219933902|emb|CAR72539.1| probable two-component system sensor histidine kinase [Mycobacterium leprae Br4923] Length=441 Score = 642 bits (1655), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/406 (84%), Positives = 366/406 (91%), Gaps = 1/406 (0%) Query 3 VFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 62 +FSALLLAGVLS LA VG G+RL+ R++E+RQR+A EW+GITV QMLQ I+ LMPLG Sbjct 1 MFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMPLG 60 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 122 AAVVDT+RDVVYLNE+AKELGLVRDRQLDDQAWRAA+QALGG+DVEFDL P KR A GRS Sbjct 61 AAVVDTYRDVVYLNEQAKELGLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAGRS 120 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 GLSVHGHARLLSE+DRRFAVVFVHDQSDY RMEAARRDFVANVSHELKTPVGAMALLAEA Sbjct 121 GLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFVANVSHELKTPVGAMALLAEA 180 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 LLASADD+ETV RFAEKVLIEANRLG MVAELIELSRLQGAERLPN+TD+DVD IVSEAI Sbjct 181 LLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSEAI 240 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 +RHKVAAD A IEVRTD PS LRVLGDQTLLVTALANLVSNAIAYSP GSLVSISRRRRG Sbjct 241 ARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRRRG 300 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 NIEIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I V Sbjct 301 DNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGV 360 Query 363 WSKPGTGSTFTLALPALIEAYHD-DERPEQAREPELRSNRSQREEE 407 WSKPGTGSTFTL++PA + Y D DE+ Q R ++ NR QREEE Sbjct 361 WSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNRPQREEE 406 >gi|254777098|ref|ZP_05218614.1| hisitidine protein kinase SenX3 [Mycobacterium avium subsp. avium ATCC 25291] Length=407 Score = 640 bits (1650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/408 (84%), Positives = 367/408 (90%), Gaps = 1/408 (0%) Query 3 VFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 62 +FSALLLAGVLS LALA G AVG RL+ R ++RQR++TEW+GITV+QML+ IV LMPLG Sbjct 1 MFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMPLG 60 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 122 AAVVD HR VVYLN+RAKELGLVRDRQLDDQAW AA+QAL G DVEFDL P KRS GRS Sbjct 61 AAVVDAHRGVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSG-GRS 119 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 GLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLAEA Sbjct 120 GLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAEA 179 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 LLASADDSETVRRFAEKVL+EANRLGDMVAELIELSRLQGAERL N+T+VDVD++V+EAI Sbjct 180 LLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVDVDSVVNEAI 239 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 SRHKVAADNA+IEVRTDAPS LRVLGD+TLLVTALANLVSNAIAYSP GS VSISRRRRG Sbjct 240 SRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRG 299 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 NIEIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+GTI V Sbjct 300 DNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIGV 359 Query 363 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 WSKPGTGSTFTL++PA + D EQ + E+R NRSQREEELSR Sbjct 360 WSKPGTGSTFTLSIPAAVAPDRGDGESEQPQGREVRPNRSQREEELSR 407 >gi|296168091|ref|ZP_06850157.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896898|gb|EFG76526.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=406 Score = 628 bits (1619), Expect = 6e-178, Method: Compositional matrix adjust. Identities = 346/411 (85%), Positives = 370/411 (91%), Gaps = 6/411 (1%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLS L LA+G A G RL+ + +RQRV+TEW+GITV+QMLQ IVTLMP Sbjct 1 MTVFSALLLAGVLSVLGLAIGVAAGTRLSPKAAHRRQRVSTEWTGITVAQMLQRIVTLMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LG AVVD+HRDVVYLN+RA+ELGLVRDRQLDDQAW AA+QAL G DVEFDL P KR+A G Sbjct 61 LGVAVVDSHRDVVYLNDRARELGLVRDRQLDDQAWEAAQQALSGVDVEFDLRPAKRAA-G 119 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLA Sbjct 120 RSGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLA 179 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADD ETVRRFAEKVL+EANRLGDMVAELIELSRLQGAERLPN+T+V+VDT+VSE Sbjct 180 EALLASADDPETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLPNVTEVEVDTVVSE 239 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNA IEVRTDAPS LRVLGD+TLLVTALANLVSNAIAYSP GS VSISRRR Sbjct 240 AISRHKVAADNAQIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRR 299 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RG NIEIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I Sbjct 300 RGDNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSI 359 Query 361 RVWSKPGTGSTFTLALPALIEAYHD-DERPEQAREPELRSNRSQREEELSR 410 VWSKPGTGSTFTL++P AY D DE PE + E R NRSQREEELSR Sbjct 360 GVWSKPGTGSTFTLSIP----AYKDTDEEPEPPQGREARPNRSQREEELSR 406 >gi|254821075|ref|ZP_05226076.1| SenX3 [Mycobacterium intracellulare ATCC 13950] Length=407 Score = 621 bits (1601), Expect = 8e-176, Method: Compositional matrix adjust. Identities = 337/408 (83%), Positives = 365/408 (90%), Gaps = 1/408 (0%) Query 3 VFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 62 +FSALLLAGVLS LALA G AVG+RL+ R +++RQRV+TEW+GITV QML+CIV LMP+G Sbjct 1 MFSALLLAGVLSVLALAAGVAVGVRLSPRAMQRRQRVSTEWTGITVGQMLECIVALMPVG 60 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 122 AAVVD HRDVVYLN+RAKELGLVRDRQLDDQAW AA+QAL G DVEFDL P KR+ RS Sbjct 61 AAVVDVHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLQPSKRTGA-RS 119 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 GLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLAEA Sbjct 120 GLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAEA 179 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 LLASADDSETVRRFAEKVL+EANRLGDMVAELIELSRLQGAE LPN+ DVDVD +VSEAI Sbjct 180 LLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAEPLPNVVDVDVDKVVSEAI 239 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 SRHKVAA+N I VRTDAPS LRVLGD+TLL TALANLVSNAIAYSP GS VSISRRRRG Sbjct 240 SRHKVAAENTKIAVRTDAPSGLRVLGDETLLTTALANLVSNAIAYSPPGSPVSISRRRRG 299 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 N+EIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+GTI V Sbjct 300 ENVEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIGV 359 Query 363 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 WSKPGTGSTFTL++PA + D+ EQA+ ++R +RSQREEELSR Sbjct 360 WSKPGTGSTFTLSIPAAKPSPRDEGESEQAQGRDVRPDRSQREEELSR 407 >gi|342859009|ref|ZP_08715663.1| SenX3 [Mycobacterium colombiense CECT 3035] gi|342133250|gb|EGT86453.1| SenX3 [Mycobacterium colombiense CECT 3035] Length=405 Score = 617 bits (1590), Expect = 1e-174, Method: Compositional matrix adjust. Identities = 339/408 (84%), Positives = 364/408 (90%), Gaps = 3/408 (0%) Query 3 VFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLG 62 +FSALLLAGVLSALALA G VG RL+ R V++RQRV EW+GITV+QMLQ IV LMPLG Sbjct 1 MFSALLLAGVLSALALAAGVLVGFRLSPRAVQRRQRV--EWTGITVAQMLQRIVALMPLG 58 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRS 122 AAVVD HRDVVYLN+RAKELGLVRDRQLDDQAW+AA+QAL G DVEFDL P KRS GR+ Sbjct 59 AAVVDAHRDVVYLNDRAKELGLVRDRQLDDQAWQAAQQALTGVDVEFDLQPAKRSG-GRA 117 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 GLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLAEA Sbjct 118 GLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAEA 177 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 LLAS+DDSETVRRFAEKVL+EANRLGDMVAELIELSRLQGAERLP + +VDVD +V EAI Sbjct 178 LLASSDDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLPTVIEVDVDKVVGEAI 237 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 SRHKV ADNADIEVRTDAPS LRVLGD+TLLVTALANLVSNAIAYSP GS VSISRRRRG Sbjct 238 SRHKVGADNADIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRG 297 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 N+EIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I V Sbjct 298 DNVEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGV 357 Query 363 WSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 WSKPGTGSTFTL++PA + + D + EQ + R NRSQREEELSR Sbjct 358 WSKPGTGSTFTLSIPAAMASDQDHDESEQTPGRDARPNRSQREEELSR 405 >gi|183980839|ref|YP_001849130.1| two-component sensor histidine kinase SenX3 [Mycobacterium marinum M] gi|183174165|gb|ACC39275.1| two-component sensor histidine kinase SenX3 [Mycobacterium marinum M] Length=408 Score = 598 bits (1543), Expect = 4e-169, Method: Compositional matrix adjust. Identities = 342/410 (84%), Positives = 369/410 (90%), Gaps = 2/410 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLSALALA G AVG RL+ R+V +RQ+ +TEW+GITV+QMLQ IV LMP Sbjct 1 MTVFSALLLAGVLSALALAAGVAVGARLSQRLVRRRQQASTEWTGITVAQMLQRIVALMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 +G AVVD+HRDVVYLN+RAKELGLVRDRQLDDQAW AA+QAL G DVEFDLSP KR G Sbjct 61 MGVAVVDSHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALRGSDVEFDLSPGKRPG-G 119 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 RSGLSVHG ARLLSEEDRRF VVF +DQSDYARMEA RRDFVANVSHELKTPVGAMALLA Sbjct 120 RSGLSVHGQARLLSEEDRRFTVVFAYDQSDYARMEATRRDFVANVSHELKTPVGAMALLA 179 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSE 240 EALLASADDS+TVRRFAEKVLIEANRLGDMVAELIELSRLQGAERL N+TDVDVDTIVSE Sbjct 180 EALLASADDSDTVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLHNVTDVDVDTIVSE 239 Query 241 AISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRR 300 AISRHKVAADNA+IEVRTD+ S L VLGDQTLLVTALANLVSNAIAYS GS VSISRR+ Sbjct 240 AISRHKVAADNAEIEVRTDSSSGLHVLGDQTLLVTALANLVSNAIAYSSPGSPVSISRRK 299 Query 301 RGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTI 360 RG N+EIAVTDRGIGIA EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I Sbjct 300 RGDNVEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSI 359 Query 361 RVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 VWSKPGTGSTFTL++PA A D ++P+Q R + R NRSQREEELSR Sbjct 360 GVWSKPGTGSTFTLSIPA-SSAPDDSDQPDQPRARDARPNRSQREEELSR 408 >gi|118619652|ref|YP_907984.1| two component sensor histidine kinase SenX3 [Mycobacterium ulcerans Agy99] gi|118571762|gb|ABL06513.1| two component sensor histidine kinase SenX3 [Mycobacterium ulcerans Agy99] Length=406 Score = 596 bits (1537), Expect = 2e-168, Method: Compositional matrix adjust. Identities = 319/384 (84%), Positives = 345/384 (90%), Gaps = 2/384 (0%) Query 27 RLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVR 86 RL+ R+V +RQ+ +TEW+GITV+QMLQ IV LMP+G AVVD+HRDVVYLN+RAKELGLVR Sbjct 25 RLSQRLVRRRQQASTEWTGITVAQMLQRIVALMPMGVAVVDSHRDVVYLNDRAKELGLVR 84 Query 87 DRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVH 146 DRQLDDQAW AA+QAL G DVEFDLSP KR GRSGLSVHG ARLLSEEDRRF VVF + Sbjct 85 DRQLDDQAWEAAQQALRGSDVEFDLSPGKRPG-GRSGLSVHGQARLLSEEDRRFTVVFAY 143 Query 147 DQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANR 206 DQSDYARMEA RRDFVANVSHELKTPVGAMALLAEALLASADDS+TVRRFAEKVLIEANR Sbjct 144 DQSDYARMEATRRDFVANVSHELKTPVGAMALLAEALLASADDSDTVRRFAEKVLIEANR 203 Query 207 LGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRV 266 LGDMVAELIELSRLQGAERL N+TDVDVDTIVSEAISRHKVAADNA+IEVRTD+ S L V Sbjct 204 LGDMVAELIELSRLQGAERLHNVTDVDVDTIVSEAISRHKVAADNAEIEVRTDSSSGLHV 263 Query 267 LGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFE 326 LGDQTLLVTALANLVSNAIAYS GS VSISRR+RG N+EIAVTDRGIGIA EDQERVFE Sbjct 264 LGDQTLLVTALANLVSNAIAYSSPGSPVSISRRKRGDNVEIAVTDRGIGIALEDQERVFE 323 Query 327 RFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDD 386 RFFRGDKARSRATGGSGLGLAIVKHVAANH+G+I VWSKPGTGSTFTL++P A D Sbjct 324 RFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGVWSKPGTGSTFTLSIPT-SSAPDDS 382 Query 387 ERPEQAREPELRSNRSQREEELSR 410 ++P+Q R + R NRSQREEELSR Sbjct 383 DQPDQPRGRDARPNRSQREEELSR 406 >gi|120401845|ref|YP_951674.1| histidine kinase [Mycobacterium vanbaalenii PYR-1] gi|119954663|gb|ABM11668.1| histidine kinase [Mycobacterium vanbaalenii PYR-1] Length=401 Score = 543 bits (1399), Expect = 2e-152, Method: Compositional matrix adjust. Identities = 274/365 (76%), Positives = 317/365 (87%), Gaps = 3/365 (0%) Query 25 GMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGL 84 G R+ R+ E RQR + E +GITVSQML+ IV+ P+G AVVDT+RDVVY N RA+ELGL Sbjct 25 GARVVPRLREHRQRRSAEQAGITVSQMLERIVSQSPVGMAVVDTYRDVVYTNGRAQELGL 84 Query 85 VRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVV 143 VRDR LDD+AW AA +AL GE V FDLSPRKRS GRSGLS+ GH +LL+E+DRRFAVV Sbjct 85 VRDRLLDDRAWVAAERALATGEPVGFDLSPRKRSQPGRSGLSIRGHVQLLTEQDRRFAVV 144 Query 144 FVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIE 203 +V DQS++ARMEA RRDFVANVSHELKTPVGAM +LAEA+LASADD +TVR FAEK++ E Sbjct 145 YVDDQSEHARMEATRRDFVANVSHELKTPVGAMGVLAEAVLASADDPDTVRHFAEKMVTE 204 Query 204 ANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSN 263 +NRL +MV ELIELSRLQGAERLP++ VDVDT+VSEA+SRHKVAADNADI + TDAP+ Sbjct 205 SNRLANMVGELIELSRLQGAERLPDLGTVDVDTVVSEALSRHKVAADNADIVITTDAPTG 264 Query 264 LRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQER 323 +VLGDQTLLVTA+ANLVSNAIAYSP GS VSISRRRRG NIEIAVTDRGIGIAPEDQER Sbjct 265 YQVLGDQTLLVTAIANLVSNAIAYSPNGSAVSISRRRRGGNIEIAVTDRGIGIAPEDQER 324 Query 324 VFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPAL--IE 381 VFERFFR DKARSRATGG+GLGLAIVKHVAANH+G+IR+WS+PGTGSTFTL++PA ++ Sbjct 325 VFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGSIRLWSQPGTGSTFTLSIPAALPLD 384 Query 382 AYHDD 386 + DD Sbjct 385 PHGDD 389 >gi|289756565|ref|ZP_06515943.1| predicted protein [Mycobacterium tuberculosis T85] gi|289712129|gb|EFD76141.1| predicted protein [Mycobacterium tuberculosis T85] Length=269 Score = 536 bits (1381), Expect = 2e-150, Method: Compositional matrix adjust. Identities = 268/269 (99%), Positives = 269/269 (100%), Gaps = 0/269 (0%) Query 142 VVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVL 201 +VFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVL Sbjct 1 MVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVL 60 Query 202 IEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAP 261 IEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAP Sbjct 61 IEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAP 120 Query 262 SNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQ 321 SNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQ Sbjct 121 SNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQ 180 Query 322 ERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIE 381 ERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIE Sbjct 181 ERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIE 240 Query 382 AYHDDERPEQAREPELRSNRSQREEELSR 410 AYHDDERPEQAREPELRSNRSQREEELSR Sbjct 241 AYHDDERPEQAREPELRSNRSQREEELSR 269 >gi|126433264|ref|YP_001068955.1| histidine kinase [Mycobacterium sp. JLS] gi|126233064|gb|ABN96464.1| histidine kinase [Mycobacterium sp. JLS] Length=392 Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 280/392 (72%), Positives = 323/392 (83%), Gaps = 1/392 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 ++V SALL+ V++ L L VG VG+ LT RV E+R+R A E +GITVSQML IV+ P Sbjct 1 MSVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSAT 119 +G VVD RDVVY N RA+ELGLVRDR LD++AW AA+ L GEDV+ DLSPRK + Sbjct 61 VGIVVVDKFRDVVYSNVRAEELGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHP 120 Query 120 GRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALL 179 GRSGLSV G ARLL++ DRRFAVV+V D S+YARMEA RRDFVANVSHELKTPVGAM LL Sbjct 121 GRSGLSVRGAARLLTKADRRFAVVYVDDHSEYARMEATRRDFVANVSHELKTPVGAMGLL 180 Query 180 AEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVS 239 AEALLASADD ETVRRFA K++ EA+RL DM+ ELIELSRLQG ERLP++ VDVDT+VS Sbjct 181 AEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVS 240 Query 240 EAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRR 299 EA+SRHKVAADNADI + TDAP+ +VLGDQTLLV ALANLVSNAIAYSPRG+ VS+SRR Sbjct 241 EALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRR 300 Query 300 RRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGT 359 RRG NIEI+VTDRGIGI +DQERVFERFFR DKARSRATGG+GLGLAIVKHVAANH+G Sbjct 301 RRGDNIEISVTDRGIGIDKDDQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGA 360 Query 360 IRVWSKPGTGSTFTLALPALIEAYHDDERPEQ 391 IR+WS+PGTGSTFTL++PA D+ P Q Sbjct 361 IRLWSQPGTGSTFTLSIPAYPRPQEVDDEPSQ 392 >gi|118471880|ref|YP_885339.1| sensor histidine kinase SenX3 [Mycobacterium smegmatis str. MC2 155] gi|218547420|sp|A0QR01.1|SENX3_MYCS2 RecName: Full=Signal-transduction histidine kinase senX3 gi|118173167|gb|ABK74063.1| sensor histidine kinase SenX3 [Mycobacterium smegmatis str. MC2 155] Length=384 Score = 505 bits (1301), Expect = 4e-141, Method: Compositional matrix adjust. Identities = 252/349 (73%), Positives = 300/349 (86%), Gaps = 2/349 (0%) Query 45 GITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL-G 103 G+TVSQMLQ I +L P+G AVVDT DVVY N+RA EL +VRDR LDD+AW+AA++ Sbjct 33 GMTVSQMLQHITSLSPMGVAVVDTFNDVVYSNDRAVELNVVRDRILDDRAWQAAQRVFET 92 Query 104 GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVA 163 G+DVE DLSP K + GRSG+SV G RLL+++DRRFAVV++ DQS++ARMEA RRDFVA Sbjct 93 GQDVEVDLSPLKVANPGRSGISVRGKVRLLTDDDRRFAVVYIDDQSEHARMEATRRDFVA 152 Query 164 NVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGA 223 NVSHELKTPVGAM++LAEALLASADD +TVRRFAEK++ E++RL DM+ ELIELSRLQGA Sbjct 153 NVSHELKTPVGAMSVLAEALLASADDPDTVRRFAEKMVAESHRLADMIGELIELSRLQGA 212 Query 224 ERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSN 283 ERLP++ VDVD+IVSEA+SRHKVAADN+ I + TDAP+ RVLGD+ LLVTA+ANLVSN Sbjct 213 ERLPDLDAVDVDSIVSEAVSRHKVAADNSQISITTDAPTGYRVLGDEGLLVTAIANLVSN 272 Query 284 AIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSG 343 AIAYSP G+ VSISRR+RG NIEIAVTDRGIGIA +DQERVFERFFR DKARSRATGG+G Sbjct 273 AIAYSPNGTDVSISRRKRGGNIEIAVTDRGIGIAKDDQERVFERFFRVDKARSRATGGTG 332 Query 344 LGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEA-YHDDERPEQ 391 LGLAIVKHVAANH+G+IR+WS+PGTGSTFTL++P + H DER +Q Sbjct 333 LGLAIVKHVAANHNGSIRLWSQPGTGSTFTLSIPEYPDPESHSDEREDQ 381 >gi|108797640|ref|YP_637837.1| histidine kinase [Mycobacterium sp. MCS] gi|119866727|ref|YP_936679.1| histidine kinase [Mycobacterium sp. KMS] gi|108768059|gb|ABG06781.1| histidine kinase [Mycobacterium sp. MCS] gi|119692816|gb|ABL89889.1| histidine kinase [Mycobacterium sp. KMS] Length=392 Score = 504 bits (1299), Expect = 7e-141, Method: Compositional matrix adjust. Identities = 280/392 (72%), Positives = 322/392 (83%), Gaps = 1/392 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 ++V SALL+ V++ L L VG VG+ LT RV E+R+R A E +GITVSQML IV+ P Sbjct 1 MSVASALLMTAVVALLTLLVGVGVGVALTPRVAERRRRRAAETAGITVSQMLAHIVSSSP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSAT 119 +G VVD RDVVY N RA+ELGLVRDR LD++AW AA+ L GEDV+ DLSPRK + Sbjct 61 VGIVVVDKFRDVVYSNVRAEELGLVRDRLLDERAWEAAQHTLSTGEDVQVDLSPRKVAHP 120 Query 120 GRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALL 179 GRSGLSV G ARLL+ DRRFAVV+V D S+YARMEA RRDFVANVSHELKTPVGAM LL Sbjct 121 GRSGLSVRGAARLLTRADRRFAVVYVDDHSEYARMEATRRDFVANVSHELKTPVGAMGLL 180 Query 180 AEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVS 239 AEALLASADD ETVRRFA K++ EA+RL DM+ ELIELSRLQG ERLP++ VDVDT+VS Sbjct 181 AEALLASADDPETVRRFAGKMVDEAHRLADMIGELIELSRLQGGERLPDLGVVDVDTVVS 240 Query 240 EAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRR 299 EA+SRHKVAADNADI + TDAP+ +VLGDQTLLV ALANLVSNAIAYSPRG+ VS+SRR Sbjct 241 EALSRHKVAADNADIAITTDAPTGFKVLGDQTLLVAALANLVSNAIAYSPRGTPVSVSRR 300 Query 300 RRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGT 359 RRG NIEI+VTDRGIGI +DQERVFERFFR DKARSRATGG+GLGLAIVKHVAANH+G Sbjct 301 RRGDNIEISVTDRGIGIDKDDQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGA 360 Query 360 IRVWSKPGTGSTFTLALPALIEAYHDDERPEQ 391 IR+WS+PGTGSTFTL++PA D+ P Q Sbjct 361 IRLWSQPGTGSTFTLSIPAYPRPEEVDDEPSQ 392 >gi|9964000|gb|AAG09796.1|AF258346_1 hisitidine protein kinase SenX3 [Mycobacterium smegmatis str. MC2 155] Length=396 Score = 499 bits (1284), Expect = 5e-139, Method: Compositional matrix adjust. Identities = 250/349 (72%), Positives = 299/349 (86%), Gaps = 2/349 (0%) Query 45 GITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL-G 103 G+TVSQMLQ I +L P+G AVVDT DVVY N+RA EL +VRDR LDD+AW+AA++ Sbjct 45 GMTVSQMLQHITSLSPMGVAVVDTFNDVVYSNDRAVELNVVRDRILDDRAWQAAQRVFET 104 Query 104 GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVA 163 G+DVE DLSP K + GRSG+SV G RLL+++DRRFAVV++ DQS++ARMEA RRDFVA Sbjct 105 GQDVEVDLSPLKVANPGRSGISVRGKVRLLTDDDRRFAVVYIDDQSEHARMEATRRDFVA 164 Query 164 NVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGA 223 NVSHELKTPVGAM++LAEALLASADD +TVRRFAEK++ E++RL DM+ ELIELSRLQGA Sbjct 165 NVSHELKTPVGAMSVLAEALLASADDPDTVRRFAEKMVAESHRLADMIGELIELSRLQGA 224 Query 224 ERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSN 283 ERLP++ VDVD+IVSEA+SRHKVAADN+ I + TDAP+ RVLGD+ LLVTA+ANLVSN Sbjct 225 ERLPDLDAVDVDSIVSEAVSRHKVAADNSQISITTDAPTGYRVLGDEGLLVTAIANLVSN 284 Query 284 AIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSG 343 AIAYS + + VSISRR+RG NIEIAVTDRGIGIA +DQERVFERFFR DKARSRATGG+G Sbjct 285 AIAYSAQRNDVSISRRKRGGNIEIAVTDRGIGIAKDDQERVFERFFRVDKARSRATGGTG 344 Query 344 LGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEA-YHDDERPEQ 391 LGLAIVKHVAANH+G+IR+WS+PGTGSTFTL++P + H DER +Q Sbjct 345 LGLAIVKHVAANHNGSIRLWSQPGTGSTFTLSIPEYPDPESHSDEREDQ 393 >gi|315442359|ref|YP_004075238.1| histidine kinase [Mycobacterium sp. Spyr1] gi|315260662|gb|ADT97403.1| histidine kinase [Mycobacterium sp. Spyr1] Length=403 Score = 493 bits (1269), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 261/359 (73%), Positives = 304/359 (85%), Gaps = 1/359 (0%) Query 21 GGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAK 80 G A G+R + E+RQR +TE SGITVSQML+ IV+ P+G VVD RDVVY N+RA+ Sbjct 21 GVAFGVRAVPLLRERRQRRSTEQSGITVSQMLERIVSYSPIGIVVVDNFRDVVYKNDRAQ 80 Query 81 ELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRR 139 ELGL+ DR LDD+AW AA++ L G+ FDLSPRK S TGRSGLSV G+ RLL+EEDRR Sbjct 81 ELGLLGDRLLDDRAWVAAQRTLNTGQPQGFDLSPRKGSRTGRSGLSVRGYCRLLAEEDRR 140 Query 140 FAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEK 199 FAVV+V DQS++ARMEA RRDFVANVSHELKTPVGA+ +LAEA+LAS +D +TVR FAEK Sbjct 141 FAVVYVDDQSEHARMEATRRDFVANVSHELKTPVGALGVLAEAVLASVEDPDTVRHFAEK 200 Query 200 VLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTD 259 ++ EA+RL +MV ELIELSRLQG E LP++ VDVD +VSEA+SRHKVAADNA I + TD Sbjct 201 MVTEADRLANMVGELIELSRLQGGEPLPDLETVDVDVVVSEALSRHKVAADNAHIAITTD 260 Query 260 APSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPE 319 AP+ L+VLGDQTLLV A+ANLVSNAIAYSP GS VSISRRR G NIEIAVTDRGIGIAP Sbjct 261 APTGLQVLGDQTLLVAAVANLVSNAIAYSPNGSAVSISRRRNGDNIEIAVTDRGIGIAPA 320 Query 320 DQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPA 378 DQERVFERFFR DKARSRATGG+GLGLAIVKHVAANH+G+IR+WS+PGTGSTFTL++PA Sbjct 321 DQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGSIRLWSQPGTGSTFTLSIPA 379 >gi|333989118|ref|YP_004521732.1| two-component sensor histidine kinase [Mycobacterium sp. JDM601] gi|333485086|gb|AEF34478.1| two-component sensor histidine kinase SenX3 [Mycobacterium sp. JDM601] Length=393 Score = 491 bits (1265), Expect = 7e-137, Method: Compositional matrix adjust. Identities = 274/375 (74%), Positives = 309/375 (83%), Gaps = 4/375 (1%) Query 20 VGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERA 79 VG A G L+ R E+R+RV TE +GITVSQMLQ IV LG VVD+HRDVVYLNERA Sbjct 20 VGVAAGFWLSPRFAERRRRVHTERAGITVSQMLQQIVAHASLGIVVVDSHRDVVYLNERA 79 Query 80 KELGLVRDRQLDDQAWRAARQALGGE-DVEFDLSPRKRSATG-RSGLS-VHGHARLLSEE 136 ELGLV R LDD AW AA+ AL GE +V+FDLS KR+A RS S V G+ARLLS+E Sbjct 80 TELGLVHGRLLDDDAWAAAQLALDGEQEVDFDLSAAKRAAGATRSEFSAVRGYARLLSDE 139 Query 137 DRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRF 196 DRRFAVV V DQS+ ARMEA+RRDFVANVSHELKTPVGAM LLAEALLASADD E VR F Sbjct 140 DRRFAVVIVDDQSEQARMEASRRDFVANVSHELKTPVGAMGLLAEALLASADDPEAVRPF 199 Query 197 AEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEV 256 AEKVL+EANRL +M+ ELIELSRLQGA+ LP++ VDVD++V+EAISRHKVAADNA+I + Sbjct 200 AEKVLLEANRLANMIGELIELSRLQGADPLPDLGAVDVDSVVNEAISRHKVAADNAEITI 259 Query 257 RTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGI 316 TDAPS RVLGD+ LLVTALANLVSNAIAYSP G+ VSISRR R +EIAVTDRGIGI Sbjct 260 TTDAPSGFRVLGDEPLLVTALANLVSNAIAYSPHGAPVSISRRSRDGFVEIAVTDRGIGI 319 Query 317 APEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLAL 376 A +DQ+RVFERFFRGDKARSRATGGSGLGLAIVKHVAANH+GTI +WS+PGTGSTFTLA+ Sbjct 320 ARKDQQRVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTISLWSQPGTGSTFTLAI 379 Query 377 PALIEAYHDDERPEQ 391 PA + D E+ EQ Sbjct 380 PAY-QGSVDHEKEEQ 393 >gi|145220689|ref|YP_001131367.1| histidine kinase [Mycobacterium gilvum PYR-GCK] gi|145213175|gb|ABP42579.1| histidine kinase [Mycobacterium gilvum PYR-GCK] Length=402 Score = 487 bits (1254), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 262/359 (73%), Positives = 306/359 (86%), Gaps = 1/359 (0%) Query 21 GGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAK 80 G A+G+R R+ E+RQR + E SGITVSQML+ IV+ P+G AVVD RDVVY N+RA+ Sbjct 21 GVAIGVRAVPRLRERRQRRSAEQSGITVSQMLERIVSFSPIGIAVVDNFRDVVYKNDRAQ 80 Query 81 ELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRR 139 ELGL+ DR LDD+AW AA++ L GE FDLSPRK S TGRSGLSV G+ RLL+EEDRR Sbjct 81 ELGLLGDRLLDDRAWVAAQRTLTTGEPHGFDLSPRKGSRTGRSGLSVRGYCRLLAEEDRR 140 Query 140 FAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEK 199 FAVV+V DQS++ARMEA RRDFVANVSHELKTPVGA+ +LAEA+LAS +D +TVR FAEK Sbjct 141 FAVVYVDDQSEHARMEATRRDFVANVSHELKTPVGALGVLAEAVLASVEDPDTVRHFAEK 200 Query 200 VLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTD 259 ++ EA+RL +MV ELIELSRLQG E LP++ VDVD +VSEA+SRHKVAADNADI + TD Sbjct 201 MVTEADRLANMVGELIELSRLQGGEPLPDLEAVDVDVVVSEALSRHKVAADNADIAITTD 260 Query 260 APSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPE 319 AP+ +VLGDQTLLV A+ANLVSNAIAYSP GS VSISRRR G NI+IAVTDRGIGIAP Sbjct 261 APTGFQVLGDQTLLVAAVANLVSNAIAYSPNGSAVSISRRRNGDNIQIAVTDRGIGIAPA 320 Query 320 DQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPA 378 DQERVFERFFR DKARSRATGG+GLGLAIVKHVAANH+G+IR+WS+PGTGSTFTL++PA Sbjct 321 DQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGSIRLWSQPGTGSTFTLSIPA 379 >gi|169631127|ref|YP_001704776.1| sensor-like histidine kinase senX3 [Mycobacterium abscessus ATCC 19977] gi|169243094|emb|CAM64122.1| Sensor-like histidine kinase senX3 [Mycobacterium abscessus] Length=493 Score = 461 bits (1187), Expect = 8e-128, Method: Compositional matrix adjust. Identities = 234/335 (70%), Positives = 276/335 (83%), Gaps = 2/335 (0%) Query 44 SGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALG 103 +G+TVSQML+ IV + P G VVD H+DVV +N RA+ELGLVRDRQLD QAW AA++ L Sbjct 43 TGLTVSQMLERIVAISPTGIVVVDKHQDVVLVNARARELGLVRDRQLDGQAWNAAQRTLA 102 Query 104 -GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFV 162 GE VE DL+ + R A GR+G S+ GH R LS+ D R+ V++V D S++ RMEA RRDFV Sbjct 103 TGEAVEVDLTTKPR-APGRAGFSLRGHVRRLSDADTRWVVIYVDDDSEHVRMEATRRDFV 161 Query 163 ANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQG 222 ANVSHELKTPVGAM +LAEALL S+DD ETVR F E+VL E+ RLG+MV ELI LSRLQG Sbjct 162 ANVSHELKTPVGAMGVLAEALLESSDDPETVRHFGEQVLAESRRLGNMVTELIALSRLQG 221 Query 223 AERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVS 282 AE+LP++ VDVD +VSEA+SR KVAA+NADI V TDAPS V GD TLL+TA++NLV+ Sbjct 222 AEKLPDLEVVDVDFVVSEALSRSKVAAENADIAVTTDAPSGFEVRGDPTLLITAISNLVA 281 Query 283 NAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGS 342 NAIAYSP+GS VSISRRRRG +EIAVTDRGIGIA E QERVFERFFR DKARSR TGG+ Sbjct 282 NAIAYSPQGSPVSISRRRRGDKVEIAVTDRGIGIAKEHQERVFERFFRVDKARSRDTGGT 341 Query 343 GLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALP 377 GLGLAIVKHVAANH+G I++WS+PGTGSTFTL+LP Sbjct 342 GLGLAIVKHVAANHNGVIKLWSQPGTGSTFTLSLP 376 >gi|312141111|ref|YP_004008447.1| two component system sensor kinase [Rhodococcus equi 103S] gi|325674079|ref|ZP_08153769.1| sensor histidine kinase [Rhodococcus equi ATCC 33707] gi|311890450|emb|CBH49768.1| two component system sensor kinase [Rhodococcus equi 103S] gi|325555344|gb|EGD25016.1| sensor histidine kinase [Rhodococcus equi ATCC 33707] Length=413 Score = 426 bits (1095), Expect = 4e-117, Method: Compositional matrix adjust. Identities = 241/382 (64%), Positives = 290/382 (76%), Gaps = 6/382 (1%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TV A++LA + + VGG V RL+ R E+++ A G+T+SQ+L IV Sbjct 1 MTVVQAVILAVATAIVGYVVGGVVVPRLSRRHAERQKAQA----GLTMSQVLDLIVLTSE 56 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSAT 119 G AVVD DVV +N RA+ELGLVR+R LDD+AW AA + L GE VE DL+ R Sbjct 57 SGIAVVDKFNDVVLVNPRAEELGLVRNRMLDDRAWVAATEVLAKGEPVEVDLTART-PQR 115 Query 120 GRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALL 179 GR ++V G ARLLSEEDRRF VVF D S+ RMEA RRDFVANVSHELKTPVGAM LL Sbjct 116 GRDKIAVRGVARLLSEEDRRFVVVFADDDSEQVRMEATRRDFVANVSHELKTPVGAMGLL 175 Query 180 AEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVS 239 AEALL SADD ++VR F ++VL E+ RLG+MV ELI LSRLQGAE+LP++ VDVD +++ Sbjct 176 AEALLESADDPDSVRYFGQRVLSESARLGNMVTELIALSRLQGAEKLPDLEVVDVDDVIA 235 Query 240 EAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRR 299 EA+ R VAA+ ADI V DAPS L V+GD+TLLVTAL+NLV NAIAYSP+G+ VS+SR Sbjct 236 EALRRSSVAAEAADITVHADAPSGLEVMGDRTLLVTALSNLVENAIAYSPKGTPVSVSRT 295 Query 300 RRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGT 359 RG ++ IAVTDRGIGIA EDQERVFERFFR DKARSRATGG+GLGLAIVKHVAANH+G+ Sbjct 296 VRGDDVAIAVTDRGIGIAKEDQERVFERFFRVDKARSRATGGTGLGLAIVKHVAANHNGS 355 Query 360 IRVWSKPGTGSTFTLALPALIE 381 I +WS+PGTGSTFTL +PA E Sbjct 356 IDLWSRPGTGSTFTLRIPAHFE 377 >gi|111019062|ref|YP_702034.1| sensor kinase, two-component system [Rhodococcus jostii RHA1] gi|110818592|gb|ABG93876.1| sensor kinase, two-component system [Rhodococcus jostii RHA1] Length=397 Score = 423 bits (1088), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 239/402 (60%), Positives = 287/402 (72%), Gaps = 6/402 (1%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 ++V A+LLA V + VGG + L++R Q QR+ E SG+T+SQ+L IV Sbjct 1 MSVVQAVLLAIVGGFVGYLVGGVLIPMLSTR---QAQRM-EEKSGLTMSQVLDLIVLASE 56 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL-GGEDVEFDLSPRKRSAT 119 G AVVD DVV N RA+ELGLVR+R +DD+AW AA + L GE VE DLS K Sbjct 57 SGIAVVDQFHDVVLFNPRAEELGLVRNRLVDDRAWVAALRVLETGEPVEVDLST-KNPQR 115 Query 120 GRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALL 179 GR ++V G ARLLS+ED F V+F D S+ RMEA RRDFVANVSHELKTPVGAM LL Sbjct 116 GRDRIAVRGTARLLSKEDHNFVVLFADDDSEQVRMEATRRDFVANVSHELKTPVGAMGLL 175 Query 180 AEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVS 239 AEALL SADD E+VR F E+VL E+ RLG MV ELI LSRLQGAE+LP++ V VD +V Sbjct 176 AEALLESADDPESVRHFGERVLSESVRLGKMVTELIALSRLQGAEKLPDLEAVSVDEVVD 235 Query 240 EAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRR 299 EA+ R K++A+ A I V TD S VLGD+ LLVTAL+NLV NAIAYSP+G+ VS+SR Sbjct 236 EALQRCKISAEAAGIAVTTDHSSGYEVLGDRALLVTALSNLVQNAIAYSPKGAPVSVSRS 295 Query 300 RRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGT 359 RG N+ I+VTDRG GIA DQERVFERFFR DKAR+RATGG+GLGLAIVKHVAANH+G+ Sbjct 296 IRGDNVAISVTDRGEGIAKADQERVFERFFRVDKARARATGGTGLGLAIVKHVAANHNGS 355 Query 360 IRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNR 401 I +WSKPGTGSTFTL +PA IE + RE + + R Sbjct 356 IDLWSKPGTGSTFTLQIPAHIETVDAESGNVGKRETGMEAKR 397 >gi|54027161|ref|YP_121403.1| putative two-component system sensor kinase [Nocardia farcinica IFM 10152] gi|54018669|dbj|BAD60039.1| putative two-component system sensor kinase [Nocardia farcinica IFM 10152] Length=414 Score = 422 bits (1084), Expect = 7e-116, Method: Compositional matrix adjust. Identities = 224/339 (67%), Positives = 262/339 (78%), Gaps = 2/339 (0%) Query 44 SGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALG 103 SG+T+SQ+L IV G AVVD +RDVV +N RA+ELGLVR+R LD++AW A + L Sbjct 40 SGLTMSQVLDLIVLASESGIAVVDQYRDVVLVNPRAEELGLVRNRLLDERAWAAVEKVLA 99 Query 104 -GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFV 162 GE EFDL+ K GRS ++V G AR LS+E+ F V+F D S+ ARMEA RRDFV Sbjct 100 TGESAEFDLTA-KNPLPGRSRIAVRGVARPLSQEETGFTVLFADDDSEQARMEATRRDFV 158 Query 163 ANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQG 222 ANVSHELKTPVGAM+LLAEALL SADD E VR F ++VL E+ RLG MV ELI LSRLQG Sbjct 159 ANVSHELKTPVGAMSLLAEALLESADDPEAVRHFGQRVLGESRRLGKMVTELIALSRLQG 218 Query 223 AERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVS 282 AE+LP + VDVDT+V +A+ R + AA+ A I V TD PS L VLGD+TLLVTAL+NLV Sbjct 219 AEKLPELEVVDVDTVVMQAVDRSRTAAEAAGITVSTDRPSGLEVLGDETLLVTALSNLVE 278 Query 283 NAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGS 342 NAIAYSP GS VS+SR RG + +AVTDRGIGIA EDQERVFERFFR DKARSRATGG+ Sbjct 279 NAIAYSPPGSHVSVSRSLRGKYVAMAVTDRGIGIAKEDQERVFERFFRSDKARSRATGGT 338 Query 343 GLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIE 381 GLGLAIVKHVAANH+G I +WSK GTGSTFTL +PA +E Sbjct 339 GLGLAIVKHVAANHNGEITLWSKLGTGSTFTLRIPAHLE 377 >gi|226361155|ref|YP_002778933.1| two-component histidine kinase SenX3 [Rhodococcus opacus B4] gi|226239640|dbj|BAH49988.1| two-component histidine kinase SenX3 [Rhodococcus opacus B4] Length=402 Score = 421 bits (1082), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 236/382 (62%), Positives = 281/382 (74%), Gaps = 6/382 (1%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 ++V A+LLA V + VGG + L++R Q QR+ E +G+T+SQ+L IV Sbjct 1 MSVVQAVLLAIVGGFVGYLVGGVLIPMLSTR---QAQRM-EETAGLTMSQVLDLIVLASE 56 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL-GGEDVEFDLSPRKRSAT 119 G AVVD DVV N RA+ELGLVR+R +DD+AW AA + L GE VE DLS K Sbjct 57 SGIAVVDQFHDVVLFNPRAEELGLVRNRLVDDRAWVAALRVLETGEPVEVDLST-KTPQR 115 Query 120 GRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALL 179 GR ++V G ARLLS+ED F V+F D S+ RMEA RRDFVANVSHELKTPVGAM LL Sbjct 116 GRDRIAVRGTARLLSKEDHNFVVLFADDDSEQVRMEATRRDFVANVSHELKTPVGAMGLL 175 Query 180 AEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVS 239 AEALL SADD E+VR F E+VL E+ RLG MV ELI LSRLQGAE+LP++ V VD +V Sbjct 176 AEALLESADDPESVRHFGERVLGESVRLGKMVTELIALSRLQGAEKLPDLEAVSVDEVVD 235 Query 240 EAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRR 299 EA+ R K++A+ A I V TD S VLGD+ LLVTAL+NLV NAIAYSP+GS VS+SR Sbjct 236 EALQRCKISAEAAGIAVTTDHHSGYEVLGDRALLVTALSNLVQNAIAYSPKGSPVSVSRS 295 Query 300 RRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGT 359 RG N+ I+VTDRG GIA DQERVFERFFR DKAR+RATGG+GLGLAIVKHVAANH+G+ Sbjct 296 IRGDNVAISVTDRGEGIAKADQERVFERFFRVDKARARATGGTGLGLAIVKHVAANHNGS 355 Query 360 IRVWSKPGTGSTFTLALPALIE 381 I +WSKPGTGSTFTL +PA IE Sbjct 356 IDLWSKPGTGSTFTLQIPAHIE 377 >gi|229490606|ref|ZP_04384444.1| His Kinase A domain protein [Rhodococcus erythropolis SK121] gi|229322426|gb|EEN88209.1| His Kinase A domain protein [Rhodococcus erythropolis SK121] Length=411 Score = 421 bits (1081), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 234/363 (65%), Positives = 282/363 (78%), Gaps = 6/363 (1%) Query 20 VGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERA 79 VGG + RL+SR Q QR + E +G+T+SQ+L IV G AVVD DVV N RA Sbjct 20 VGGVLVPRLSSR---QSQR-SDEQTGLTMSQVLDLIVLASESGIAVVDGFHDVVLFNPRA 75 Query 80 KELGLVRDRQLDDQAWRAARQAL-GGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDR 138 +ELGLV++R +D++AWRAA++ L G+ VE DL+ + + GR ++V G ARLLS++DR Sbjct 76 EELGLVKNRLVDERAWRAAQEVLRTGQPVEVDLTAQT-AQRGRDKIAVRGTARLLSKDDR 134 Query 139 RFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAE 198 F V+F D S+ RMEA RRDFVANVSHELKTPVGAM+LLAEALL SADD E+VR F E Sbjct 135 NFVVLFADDDSEQVRMEATRRDFVANVSHELKTPVGAMSLLAEALLESADDPESVRHFGE 194 Query 199 KVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRT 258 +VL E+ RLG MV ELI LSRLQGAE+LP++ VDVDT+VSEA+SR ++A+ A I V T Sbjct 195 RVLGESIRLGKMVTELIALSRLQGAEKLPDLDVVDVDTVVSEALSRSNLSAEAAGITVTT 254 Query 259 DAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAP 318 D PS L VLGDQTLLVTAL+NL+ NAIAYSP+GS VS+SR RG N+ IAVTDRG GIA Sbjct 255 DHPSGLEVLGDQTLLVTALSNLIENAIAYSPKGSPVSVSRSVRGDNVAIAVTDRGEGIAK 314 Query 319 EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPA 378 DQERVFERFFR DKARSR TGG+GLGLAIVKHVAANH+G+I +WSKPGTGSTFTL +PA Sbjct 315 ADQERVFERFFRVDKARSRQTGGTGLGLAIVKHVAANHNGSIELWSKPGTGSTFTLQIPA 374 Query 379 LIE 381 +E Sbjct 375 HVE 377 >gi|226305110|ref|YP_002765068.1| two-component histidine kinase SenX3 [Rhodococcus erythropolis PR4] gi|226184225|dbj|BAH32329.1| two-component histidine kinase SenX3 [Rhodococcus erythropolis PR4] Length=411 Score = 420 bits (1080), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 234/363 (65%), Positives = 282/363 (78%), Gaps = 6/363 (1%) Query 20 VGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERA 79 VGG + RL+SR Q QR + E +G+T+SQ+L IV G AVVD DVV N RA Sbjct 20 VGGVLVPRLSSR---QSQR-SDEQTGLTMSQVLDLIVLASESGIAVVDGFHDVVLFNPRA 75 Query 80 KELGLVRDRQLDDQAWRAARQAL-GGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDR 138 +ELGLV++R +D++AWRAA++ L G+ VE DL+ + + GR ++V G ARLLS++DR Sbjct 76 EELGLVKNRLVDERAWRAAQEVLRTGQAVEVDLTAQT-AQRGRDKIAVRGTARLLSKDDR 134 Query 139 RFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAE 198 F V+F D S+ RMEA RRDFVANVSHELKTPVGAM+LLAEALL SADD E+VR F E Sbjct 135 NFVVLFADDDSEQVRMEATRRDFVANVSHELKTPVGAMSLLAEALLESADDPESVRHFGE 194 Query 199 KVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRT 258 +VL E+ RLG MV ELI LSRLQGAE+LP++ VDVDT+VSEA+SR ++A+ A I V T Sbjct 195 RVLGESIRLGKMVTELIALSRLQGAEKLPDLDVVDVDTVVSEALSRSNLSAEAAGITVTT 254 Query 259 DAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAP 318 D PS L VLGDQTLLVTAL+NL+ NAIAYSP+GS VS+SR RG N+ IAVTDRG GIA Sbjct 255 DHPSGLEVLGDQTLLVTALSNLIENAIAYSPKGSPVSVSRSVRGDNVAIAVTDRGEGIAK 314 Query 319 EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPA 378 DQERVFERFFR DKARSR TGG+GLGLAIVKHVAANH+G+I +WSKPGTGSTFTL +PA Sbjct 315 ADQERVFERFFRVDKARSRQTGGTGLGLAIVKHVAANHNGSIELWSKPGTGSTFTLQIPA 374 Query 379 LIE 381 +E Sbjct 375 HVE 377 >gi|333918301|ref|YP_004491882.1| sensor histidine kinase [Amycolicicoccus subflavus DQS3-9A1] gi|333480522|gb|AEF39082.1| Sensor histidine kinase [Amycolicicoccus subflavus DQS3-9A1] Length=408 Score = 407 bits (1046), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 219/366 (60%), Positives = 274/366 (75%), Gaps = 5/366 (1%) Query 45 GITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL-G 103 G+TVSQ+L +V+ P+G AVVD H+ V+ N R +ELG+VR+ LDD+AW A+++ Sbjct 41 GLTVSQVLDLVVSSSPIGIAVVDEHQHVLMSNLRVEELGVVRNHLLDDRAWVASQKVFAN 100 Query 104 GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVA 163 GE V+FD+S + + R ++V GHA LL D R AV++ D S+ RMEA RRDFVA Sbjct 101 GESVDFDVSEKMQPFV-RGAVAVRGHAHLLHSADPRIAVIYAEDDSEQVRMEATRRDFVA 159 Query 164 NVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGA 223 NVSHELKTPVGA++LL EALL S DD ++VR F EK+L E+NRLG+MV+ELI LSRLQGA Sbjct 160 NVSHELKTPVGAVSLLTEALLESVDDPDSVRHFGEKMLHESNRLGNMVSELIALSRLQGA 219 Query 224 ERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSN 283 E+LP++ VDVD++VSEA+ R V+A+ A+I + TD PS L VLGD+TLLVTAL NL+SN Sbjct 220 EKLPDLDVVDVDSVVSEAMERSSVSAEAAEITITTDFPSGLEVLGDRTLLVTALTNLLSN 279 Query 284 AIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSG 343 AI+YSP + V+ISR R N+EI+VTDRGIGIAPE ERVFERFFR DKARSRATGG+G Sbjct 280 AISYSPPKTPVTISRNLRDTNVEISVTDRGIGIAPEYHERVFERFFRVDKARSRATGGTG 339 Query 344 LGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAR---EPELRSN 400 LGLAIVKHVAANH+G+IR+WS+PGTGSTFTL LP +EA E R EP + Sbjct 340 LGLAIVKHVAANHNGSIRMWSRPGTGSTFTLVLPVYVEADDAAEETPLGRGPGEPRVELR 399 Query 401 RSQREE 406 REE Sbjct 400 AKNREE 405 >gi|134103392|ref|YP_001109053.1| putative two-component system sensor kinase [Saccharopolyspora erythraea NRRL 2338] gi|291004389|ref|ZP_06562362.1| putative two-component system sensor kinase [Saccharopolyspora erythraea NRRL 2338] gi|133916015|emb|CAM06128.1| putative two-component system sensor kinase [Saccharopolyspora erythraea NRRL 2338] Length=402 Score = 366 bits (939), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 222/394 (57%), Positives = 276/394 (71%), Gaps = 16/394 (4%) Query 4 FSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGA 63 ++AL++A L VG A G L +R + +R + G TV+++LQ +V G Sbjct 3 YTALIIA------VLLVGAASGY-LAARATRRYER--KQPKGPTVAELLQRLVHTTDNGV 53 Query 64 AVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSATGRS 122 VV+ DVV N RA ELGL+RD Q D +A +AA QA+ GE DLSP R GR Sbjct 54 VVVNKFGDVVLHNPRADELGLIRDNQADPRARKAAEQAIATGEPTAVDLSPLGRVLRGRG 113 Query 123 GLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEA 182 +V G AR L + FAV+ D+SD R+EA RRDFVANVSHELKTPVGA+ALLAEA Sbjct 114 PAAVLGDARPLGDG---FAVIDAGDESDAVRLEATRRDFVANVSHELKTPVGALALLAEA 170 Query 183 LLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAI 242 +L +ADD E VRRF+ K+L E+ RLG +V+ELI LSRLQGAERLP +T ++VD +V EA+ Sbjct 171 VLDAADDPEEVRRFSTKILHESTRLGTLVSELIALSRLQGAERLPELTTLEVDALVEEAL 230 Query 243 SRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRG 302 R ++ A++A IE+ D PS L + GD+TLLVTAL+NLV NA++YSP GS VSISRR G Sbjct 231 GRCRIGAESAGIEIAVDEPSGLLLDGDRTLLVTALSNLVDNAVSYSPPGSPVSISRRLSG 290 Query 303 ANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRV 362 +EIAVTDRGIGIAPE QERVFERFFR D ARSRATGG+GLGLAIVKHVAANH G +++ Sbjct 291 DFVEIAVTDRGIGIAPEHQERVFERFFRVDPARSRATGGTGLGLAIVKHVAANHGGEVKL 350 Query 363 WSKPGTGSTFTLALPALIEAYHDD-ERPEQAREP 395 WS+ GTGSTFTL +P A D+ +PE R P Sbjct 351 WSRLGTGSTFTLRVPR--HAIGDEGAQPEPERAP 382 >gi|296138386|ref|YP_003645629.1| histidine kinase [Tsukamurella paurometabola DSM 20162] gi|296026520|gb|ADG77290.1| histidine kinase [Tsukamurella paurometabola DSM 20162] Length=397 Score = 365 bits (936), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 206/346 (60%), Positives = 255/346 (74%), Gaps = 9/346 (2%) Query 44 SGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL- 102 S +TV+Q+ + ++ P G VVD RDV+ N RA E LVRD+ LDD+ W + L Sbjct 38 SRMTVAQLQREVIQESPTGLVVVDRFRDVILFNHRAAEFSLVRDQLLDDRVWATVCRVLE 97 Query 103 GGEDVEFDLSPRKRSATGRSGLSVHGHARLL--SEEDRRFAVVFVHDQSDYARMEAARRD 160 G +L+ +R+ R+G++V L+ S+ D R+AVV+ D ++ RMEA RRD Sbjct 98 TGTPGTVELTVTRRA--DRAGIAVRCRVELIAGSDPDERYAVVYADDDTENKRMEATRRD 155 Query 161 FVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRL 220 FVANVSHELKTPVGA+ LLAEALL S DD E VR F +VL E+ R+G+MV ELI LSRL Sbjct 156 FVANVSHELKTPVGAIGLLAEALLESDDDPEAVRHFGSRVLSESTRMGNMVNELIALSRL 215 Query 221 QGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANL 280 QGAE+LP++ V+VD +V EA++R +VAA+ +I + D PS L + GD TLL+TALANL Sbjct 216 QGAEKLPDLGTVEVDDVVGEAVARAQVAAEANNIALIVDEPSGLEIRGDDTLLLTALANL 275 Query 281 VSNAIAYSPRGSLVSISRRRR----GANIEIAVTDRGIGIAPEDQERVFERFFRGDKARS 336 +SNAIAYSP+G+ VSISRR R A++EIAVTDRGIGIAPEDQERVFERFFR DKARS Sbjct 276 ISNAIAYSPQGTQVSISRRSRVIDGVASVEIAVTDRGIGIAPEDQERVFERFFRVDKARS 335 Query 337 RATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEA 382 R TGG+GLGLAIVKHVAANH GTI++WSKPG GSTFTL LPAL EA Sbjct 336 RMTGGTGLGLAIVKHVAANHGGTIKLWSKPGMGSTFTLVLPALTEA 381 >gi|336460429|gb|EGO39326.1| histidine kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=236 Score = 364 bits (934), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 198/237 (84%), Positives = 216/237 (92%), Gaps = 1/237 (0%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMP 60 +TVFSALLLAGVLS LALA G AVG RL+ R ++RQR++TEW+GITV+QML+ IV LMP Sbjct 1 MTVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMP 60 Query 61 LGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATG 120 LGAAVVD HRDVVYLN+RAKELGLVRDRQLDDQAW AA+QAL G DVEFDL P KRS G Sbjct 61 LGAAVVDAHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSG-G 119 Query 121 RSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLA 180 R+GLSVHG ARLLSEEDRRFAVVF HDQSDYARMEA RRDFVANVSHELKTPVGAMALLA Sbjct 120 RAGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLA 179 Query 181 EALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTI 237 EALLASADDSETVRRFAEKVL+EANRLGDMVAELIELSRLQGAERL N+T+V+VD++ Sbjct 180 EALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSV 236 >gi|319949622|ref|ZP_08023662.1| two component system sensor kinase [Dietzia cinnamea P4] gi|319436709|gb|EFV91789.1| two component system sensor kinase [Dietzia cinnamea P4] Length=398 Score = 358 bits (918), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 212/379 (56%), Positives = 261/379 (69%), Gaps = 4/379 (1%) Query 13 LSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDV 72 L+ +A +G VG + + + +R +E +G + ++LQ + P AVVD H+DV Sbjct 9 LAIVAGVIGFIVGGFVVPLINRRNERRRSEQAGPSRLEVLQGVYLQAPYALAVVDRHQDV 68 Query 73 VYLNERAKELGLVRDRQLDDQAWRAARQALG-GEDVEFDLSPRKRSATGRSGL-SVHGHA 130 V N RA ELG+V DR L + W AA+ GE FDL + TGR L SV G + Sbjct 69 VLYNRRAAELGIVDDRLLVEPVWLAAQATFTTGEPTRFDLP--AKLLTGRRRLPSVSGRS 126 Query 131 RLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDS 190 +L E + +F VVF D S++ RMEAARRDFVANVSHELKTPVGAMA+LAEALL S DD Sbjct 127 EILGEYNEQFVVVFADDDSEHRRMEAARRDFVANVSHELKTPVGAMAVLAEALLESKDDP 186 Query 191 ETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAAD 250 ++V F +V+ EA RLG MV+ELIELSRLQGAER+ + VDVD +V EA+ R A+ Sbjct 187 DSVEYFGGRVVSEAQRLGRMVSELIELSRLQGAERIRDPEPVDVDDVVDEALRRSASTAE 246 Query 251 NADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVT 310 A IE+ TDAPS L V GD+TLLVTAL NL+SNA+ YSP + VSI+R G + + VT Sbjct 247 AAGIELITDAPSGLEVRGDRTLLVTALTNLISNAVNYSPERTPVSITRGIDGDTVMLRVT 306 Query 311 DRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGS 370 DRGIGIAPE Q RVFERFFR DKARSRATGG+GLGLAIVKHVA NH+GT+ +WS+PGTGS Sbjct 307 DRGIGIAPEHQARVFERFFRVDKARSRATGGTGLGLAIVKHVAQNHNGTVSLWSRPGTGS 366 Query 371 TFTLALPALIEAYHDDERP 389 TFTL LPA +E D P Sbjct 367 TFTLELPAHVEPGGDGTTP 385 >gi|62389303|ref|YP_224705.1| two component sensor kinase [Corynebacterium glutamicum ATCC 13032] gi|145294520|ref|YP_001137341.1| hypothetical protein cgR_0475 [Corynebacterium glutamicum R] gi|21323168|dbj|BAB97796.1| Two-component system, sensory transduction histidine kinases [Corynebacterium glutamicum ATCC 13032] gi|41324637|emb|CAF19119.1| probable two component sensor kinase [Corynebacterium glutamicum ATCC 13032] gi|140844440|dbj|BAF53439.1| hypothetical protein [Corynebacterium glutamicum R] gi|344045319|gb|EGV40991.1| hypothetical protein CgS9114_05207 [Corynebacterium glutamicum S9114] Length=413 Score = 355 bits (912), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 201/394 (52%), Positives = 258/394 (66%), Gaps = 18/394 (4%) Query 8 LLAGVLSALALAVGGAVGMRLTSRVVEQRQRVA-TEWSGITVSQMLQCIVTLMPLGAAVV 66 LLA VL + + + ++ R+ + V +E TV Q+L + P G VV Sbjct 4 LLAFVLGVVLMGLALPAYTKIKDRMRRHKSAVTLSENQVTTVGQVLHLAIQGSPTGITVV 63 Query 67 DTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGE-----DVEFDLSPRKRSATGR 121 D DV+ N RA ELG+V +R +D WR A++A + DV D +PR+ G Sbjct 64 DRTGDVILSNGRAHELGIVHERSVDGNVWRVAQEAFQDQETHSLDVHPDRNPRR---PGS 120 Query 122 SGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAE 181 +V + L+ D RF +++ D+S+ RME+ARRDFVANVSHELKTPVG MALLAE Sbjct 121 RITAVQAVVKPLTLIDDRFVIIYASDESENVRMESARRDFVANVSHELKTPVGGMALLAE 180 Query 182 ALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEA 241 AL+ S+DD E V F ++ EA+R+ DM+ ELI LS+LQGAERLP+M V D I+SEA Sbjct 181 ALMESSDDPEQVEYFGSRLHREAHRMADMINELISLSKLQGAERLPDMEPVQADDIISEA 240 Query 242 ISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRR 301 I R ++AADNA+IE+ + + V D++LLVTALANL+SNAI YSP+ VS+S+ R Sbjct 241 IERTQLAADNANIEIIRGDRTGVWVEADRSLLVTALANLISNAINYSPKSVPVSVSQSIR 300 Query 302 GANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIR 361 + I VTDRGIGIAPEDQ RVFERFFR DKARSR TGG+GLGLAIVKHV ANH G+I Sbjct 301 NDVVMIRVTDRGIGIAPEDQGRVFERFFRVDKARSRQTGGTGLGLAIVKHVMANHGGSIS 360 Query 362 VWSKPGTGSTFTLALPALIEAYHDDERPEQAREP 395 +WS+PGTGSTFTL LP YH PE ++EP Sbjct 361 LWSRPGTGSTFTLELP----VYH----PE-SKEP 385 >gi|19551648|ref|NP_599650.1| signal transduction histidine kinase [Corynebacterium glutamicum ATCC 13032] Length=386 Score = 353 bits (905), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 193/354 (55%), Positives = 242/354 (69%), Gaps = 17/354 (4%) Query 47 TVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGE- 105 TV Q+L + P G VVD DV+ N RA ELG+V +R +D WR A++A + Sbjct 17 TVGQVLHLAIQGSPTGITVVDRTGDVILSNGRAHELGIVHERSVDGNVWRVAQEAFQDQE 76 Query 106 ----DVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDF 161 DV D +PR+ G +V + L+ D RF +++ D+S+ RME+ARRDF Sbjct 77 THSLDVHPDRNPRR---PGSRITAVQAVVKPLTLIDDRFVIIYASDESENVRMESARRDF 133 Query 162 VANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQ 221 VANVSHELKTPVG MALLAEAL+ S+DD E V F ++ EA+R+ DM+ ELI LS+LQ Sbjct 134 VANVSHELKTPVGGMALLAEALMESSDDPEQVEYFGSRLHREAHRMADMINELISLSKLQ 193 Query 222 GAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLV 281 GAERLP+M V D I+SEAI R ++AADNA+IE+ + + V D++LLVTALANL+ Sbjct 194 GAERLPDMEPVQADDIISEAIERTQLAADNANIEIIRGDRTGVWVEADRSLLVTALANLI 253 Query 282 SNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGG 341 SNAI YSP+ VS+S+ R + I VTDRGIGIAPEDQ RVFERFFR DKARSR TGG Sbjct 254 SNAINYSPKSVPVSVSQSIRNDVVMIRVTDRGIGIAPEDQGRVFERFFRVDKARSRQTGG 313 Query 342 SGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREP 395 +GLGLAIVKHV ANH G+I +WS+PGTGSTFTL LP YH PE ++EP Sbjct 314 TGLGLAIVKHVMANHGGSISLWSRPGTGSTFTLELP----VYH----PE-SKEP 358 >gi|300782392|ref|YP_003762683.1| two-component system histidine kinase [Amycolatopsis mediterranei U32] gi|299791906|gb|ADJ42281.1| two-component system histidine kinase [Amycolatopsis mediterranei U32] gi|340523759|gb|AEK38964.1| two-component system histidine kinase [Amycolatopsis mediterranei S699] Length=399 Score = 351 bits (900), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 204/377 (55%), Positives = 260/377 (69%), Gaps = 15/377 (3%) Query 20 VGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERA 79 + GAV +R +R+ V G TV+++L+ +V G V++ D+V N RA Sbjct 1 MAGAVVGYFLARARTRREEV--RPPGPTVAELLERLVRSSNNGIVVLNRFGDMVLHNPRA 58 Query 80 KELGLVRDRQLDDQAWRAARQAL-GGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDR 138 ELGLV+ Q D +A +AA Q + E +E DLSP + A GR +V G R L + Sbjct 59 YELGLVKVNQADPRARKAAEQVVETDEALEIDLSPLE--ARGRQPEAVLGQVRPLGDG-- 114 Query 139 RFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAE 198 F VV D S+ R+EA RRDFVANVSHELKTPVGA+ALL EA+L +A+D VRRF Sbjct 115 -FTVVEAVDHSEAIRLEAVRRDFVANVSHELKTPVGAIALLTEAVLDAAEDVAEVRRFGG 173 Query 199 KVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRT 258 K+L E+ RLG +V ELI LSRLQGAERLP++ V+VD +V EA+ R ++A++ADI + T Sbjct 174 KILRESTRLGQLVTELIALSRLQGAERLPDLNVVEVDAVVREALGRTTLSAESADIRITT 233 Query 259 DAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAP 318 D PS L + GD+TLLVTAL+NL+ NA+AYSP GS VSISRR +EIAVTDRGIGIA Sbjct 234 DNPSGLLIEGDRTLLVTALSNLLENAVAYSPAGSPVSISRRLADGMVEIAVTDRGIGIAE 293 Query 319 EDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPA 378 ++Q+RVFERF+R DKARSRATGG+GLGLAIVKHVAANH G++ +WS+ GTGSTFTL +PA Sbjct 294 DEQQRVFERFYRADKARSRATGGTGLGLAIVKHVAANHGGSVGLWSRQGTGSTFTLRIPA 353 Query 379 LIEAYHDDERPEQAREP 395 + PE A EP Sbjct 354 HVS-------PEPATEP 363 >gi|257054345|ref|YP_003132177.1| histidine kinase [Saccharomonospora viridis DSM 43017] gi|256584217|gb|ACU95350.1| histidine kinase [Saccharomonospora viridis DSM 43017] Length=416 Score = 349 bits (896), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 204/362 (57%), Positives = 253/362 (70%), Gaps = 13/362 (3%) Query 17 ALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLN 76 L VG VG SR+ R R G T +Q+L+ V G +++ D+V N Sbjct 17 GLLVGFLVGR---SRLTHSRMR----PQGPTAAQLLERFVRSSNSGVLILNRFGDLVLHN 69 Query 77 ERAKELGLVRDRQLDDQAWRAARQAL-GGEDVEFDLSPRKRSATGRSGLSVHGHARLLSE 135 RA+ELGLVRD + D +A +AA Q + GG E DLSP S R +V G R L + Sbjct 70 HRAEELGLVRDNRADARARKAAEQVVDGGTPTEVDLSPL--SVRRRGPEAVLGEVRPLGD 127 Query 136 EDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRR 195 F VV D S+ R+EA RRDFVANVSHELKTPVGA+A+LAEA+L +ADD + VRR Sbjct 128 G---FTVVEAMDHSEAVRLEATRRDFVANVSHELKTPVGAIAVLAEAVLDAADDPDEVRR 184 Query 196 FAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIE 255 F EK+L E+ RLG +V ELI LSRLQGAE+LP +T VD+DT+V EA+ R ++AA++A I+ Sbjct 185 FGEKILRESTRLGKLVTELIALSRLQGAEKLPELTVVDIDTVVDEALGRIRLAAESAGID 244 Query 256 VRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIG 315 + TD+ S L V GD+TLLVTAL+NL+ NA+AYSP GS VSISRR +E+AVTDRGIG Sbjct 245 ITTDSASGLSVEGDRTLLVTALSNLLDNAVAYSPAGSPVSISRRLVDGYVEVAVTDRGIG 304 Query 316 IAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLA 375 I DQ+RVFERF+R DKARSRATGG+GLGLAIVKHVAANH G +R+WS PG GSTFTL Sbjct 305 IPESDQQRVFERFYRADKARSRATGGTGLGLAIVKHVAANHGGEVRLWSSPGVGSTFTLR 364 Query 376 LP 377 +P Sbjct 365 IP 366 >gi|289748981|ref|ZP_06508359.1| LOW QUALITY PROTEIN: two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis T92] gi|289689568|gb|EFD56997.1| LOW QUALITY PROTEIN: two component system sensor histidine kinase senX3 [Mycobacterium tuberculosis T92] Length=201 Score = 348 bits (894), Expect = 8e-94, Method: Compositional matrix adjust. Identities = 173/173 (100%), Positives = 173/173 (100%), Gaps = 0/173 (0%) Query 238 VSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSIS 297 VSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSIS Sbjct 29 VSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSIS 88 Query 298 RRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHD 357 RRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHD Sbjct 89 RRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHD 148 Query 358 GTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 410 GTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR Sbjct 149 GTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR 201 >gi|334563886|ref|ZP_08516877.1| two-component system sensor kinase TcsS8 [Corynebacterium bovis DSM 20582] Length=409 Score = 347 bits (891), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 185/354 (53%), Positives = 236/354 (67%), Gaps = 6/354 (1%) Query 47 TVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGED 106 TV+Q+L + P VVD +VV N RA ELGLV +R L+ AW R+ + Sbjct 45 TVAQVLHFAIQSSPAAVVVVDKREEVVLSNPRAHELGLVHERSLNPAAWGVVRKVFADHE 104 Query 107 VEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVS 166 P + R +SV G +LL+ D RFAVV+ D S+ RME+ARRDFVANVS Sbjct 105 PRMVTFPPPKRRGERPVISVAGQVQLLTLLDHRFAVVYAVDDSETVRMESARRDFVANVS 164 Query 167 HELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERL 226 HELKTPVGAM+LL E LL DD E V F K++ E+ R+G M+ ELI LS+LQGAE L Sbjct 165 HELKTPVGAMSLLVETLLEVRDDPEAVTYFGNKLMGESRRMGTMITELISLSKLQGAEPL 224 Query 227 PNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIA 286 P+ + VDT++++A+SR + A+ A IE+ TD P V GD++LLVTA+ANL++NA+ Sbjct 225 PDPEIISVDTVITDALSRCRTVAEAAGIELTTDGPVGATVEGDRSLLVTAVANLITNAVN 284 Query 287 YSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGL 346 YSP + VSISR + + +TDRGIGIAPEDQ+RVFERFFR DKARSRATGG+GLGL Sbjct 285 YSPEATPVSISREATDDAVILRITDRGIGIAPEDQKRVFERFFRVDKARSRATGGTGLGL 344 Query 347 AIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDD--ERPEQAREPELR 398 AIVKHV ANH G + +WS+PGTGSTFT+ LP +H+D R EQ P+ R Sbjct 345 AIVKHVVANHGGRVSLWSRPGTGSTFTIELP----RHHEDRGRRREQVVFPDQR 394 >gi|302523819|ref|ZP_07276161.1| phosphate regulon sensor kinase PhoR [Streptomyces sp. AA4] gi|302432714|gb|EFL04530.1| phosphate regulon sensor kinase PhoR [Streptomyces sp. AA4] Length=412 Score = 347 bits (890), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 197/363 (55%), Positives = 252/363 (70%), Gaps = 6/363 (1%) Query 44 SGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQAL- 102 +G TV+++L+ ++ G V++ D+V N RA ELGLVR Q D +A +AA Q + Sbjct 37 TGPTVAELLERLIRSSNNGVIVLNRFGDLVLHNPRAYELGLVRVNQADPRARKAAEQVVE 96 Query 103 GGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFV 162 E +E DLSP + R +V G R L + F VV D S+ R+EA RRDFV Sbjct 97 TDEPMEVDLSPLENRGR-RQPEAVLGEVRPLGDG---FTVVEAVDHSEAIRLEAVRRDFV 152 Query 163 ANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQG 222 ANVSHELKTPVGA+ALL EA+L +A+D E VRRF K+L E+ RLG +V ELI LSRLQG Sbjct 153 ANVSHELKTPVGAIALLTEAVLDAAEDVEEVRRFGGKILRESTRLGQLVTELIALSRLQG 212 Query 223 AERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVS 282 AERLP++ V+VD +V EA+ R ++A++ADI + TD PS L + GD+TLLVTAL+NL+ Sbjct 213 AERLPDLNVVEVDAVVREALGRTTLSAESADITITTDTPSGLLIEGDRTLLVTALSNLLE 272 Query 283 NAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGS 342 NA+AYS GS VSISRR +EIAVTDRGIGIA ++Q+RVFERF+R DKARSRATGG+ Sbjct 273 NAVAYSSAGSPVSISRRLADGMVEIAVTDRGIGIAEDEQQRVFERFYRADKARSRATGGT 332 Query 343 GLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYH-DDERPEQAREPELRSNR 401 GLGLAIVKHVAANH G++ +WS+PGTGSTFTL +PA + D R P+ R Sbjct 333 GLGLAIVKHVAANHGGSVGLWSRPGTGSTFTLRIPAHVRTEPADTARKAAPARPDKTPER 392 Query 402 SQR 404 + R Sbjct 393 TPR 395 >gi|25026980|ref|NP_737034.1| putative sensor kinase [Corynebacterium efficiens YS-314] gi|259508537|ref|ZP_05751437.1| sensor histidine kinase [Corynebacterium efficiens YS-314] gi|23492260|dbj|BAC17234.1| putative sensor kinase [Corynebacterium efficiens YS-314] gi|259163887|gb|EEW48441.1| sensor histidine kinase [Corynebacterium efficiens YS-314] Length=413 Score = 344 bits (883), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 197/394 (50%), Positives = 252/394 (64%), Gaps = 21/394 (5%) Query 1 VTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVAT---EWSGITVSQMLQCIVT 57 ++ F A LL V++ LAL G R +R + AT E TV Q+L + Sbjct 1 MSTFFAFLLGVVVAGLALPAYGWAKERF------RRHKSATTLAENQVTTVGQVLHLAIQ 54 Query 58 LMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGED-----VEFDLS 112 P G VVD DV+ N RA LG+V R ++ WR A++A +D V ++ Sbjct 55 GSPTGITVVDRTGDVILSNGRAHSLGIVHQRTVNSDVWRVAQEAFDDKDTHTLDVNPSVN 114 Query 113 PRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTP 172 PR+ G +V + L+ D RF +++ D+S+ RME+ARRDFVANVSHELKTP Sbjct 115 PRR---PGNRVTAVRAVVKPLTLIDDRFVIIYATDESENVRMESARRDFVANVSHELKTP 171 Query 173 VGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDV 232 VG MALLAEAL+ + DD E V F ++ EA+R+ DM+ ELI LS+LQGAERLP+M V Sbjct 172 VGGMALLAEALMEAVDDPEQVEYFGARLHREAHRMADMINELISLSKLQGAERLPDMEPV 231 Query 233 DVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGS 292 VD I+ EAI R ++AADNA IE+ +++ V +++LLVTALANL+SNAI YSP+ Sbjct 232 KVDDIIDEAIERTQLAADNAQIELVRGDRTDVWVNAERSLLVTALANLISNAINYSPQSM 291 Query 293 LVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHV 352 VS+S+ + I VTDRGIGIAPEDQ RVFERFFR DKARSR TGG+GLGLAIVKHV Sbjct 292 PVSVSQNVCNDVVMIRVTDRGIGIAPEDQGRVFERFFRVDKARSRQTGGTGLGLAIVKHV 351 Query 353 AANHDGTIRVWSKPGTGSTFTLALPALIEAYHDD 386 ANH G I +WS+PGTGSTFTL LP YH + Sbjct 352 MANHGGNISLWSRPGTGSTFTLELP----VYHPE 381 >gi|336326509|ref|YP_004606475.1| two-component system sensor histidine kinase [Corynebacterium resistens DSM 45100] gi|336102491|gb|AEI10311.1| two-component system sensor histidine kinase [Corynebacterium resistens DSM 45100] Length=415 Score = 343 bits (881), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 197/398 (50%), Positives = 253/398 (64%), Gaps = 18/398 (4%) Query 4 FSALLLAGVLSALALAVGGAVGMRL---------TSRVVEQRQRVATEWSGITVSQMLQC 54 S L+ G+L+ LA VG A+G+ + R V R+ + ++ TVSQ+L Sbjct 1 MSTELIGGILAGLA--VGIAIGLFVMWAYRKNIKARRNVHTRRELQSDRVS-TVSQVLHH 57 Query 55 IVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGED---VEFDL 111 + P AVVD R VV N A ELGLV +R L+ W + L + V F L Sbjct 58 AIQSAPTAVAVVDKRRKVVLSNPSAHELGLVHERALNSAVWGVVEKVLADHEPREVNF-L 116 Query 112 SPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKT 171 P +RS R ++V G +LLS D RF VV+ D S++ RME+ARRDFVANVSHELKT Sbjct 117 PPPRRS--DRPVIAVAGQVQLLSLVDDRFVVVYATDDSEHVRMESARRDFVANVSHELKT 174 Query 172 PVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTD 231 PVGA++LL E ++ DD + V F K+ E R+ M+ ELI LS+LQGAE LP+ Sbjct 175 PVGAVSLLVETMMEVKDDPDAVEYFGGKLHREVVRMNQMITELISLSKLQGAESLPDPDI 234 Query 232 VDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRG 291 + VD I+ EAI R ++ A++A IE++TD S V GDQ+LLVT++ NL++NAI YSP G Sbjct 235 LSVDKIIDEAIDRSRMTAESAGIELKTDGKSGAMVRGDQSLLVTSVTNLLTNAINYSPEG 294 Query 292 SLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKH 351 + VSISR N+ I VTDRGIGI+ EDQ+RVFERFFR DKARSR TGG+GLGLAIVKH Sbjct 295 TPVSISREVADGNVIIRVTDRGIGISQEDQKRVFERFFRVDKARSRNTGGTGLGLAIVKH 354 Query 352 VAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERP 389 V ANH G + +WS+PGTGSTF L +PA E H RP Sbjct 355 VMANHGGRVTLWSRPGTGSTFALEMPAYDEEQHGPTRP 392 >gi|260579349|ref|ZP_05847231.1| sensor histidine kinase [Corynebacterium jeikeium ATCC 43734] gi|258602478|gb|EEW15773.1| sensor histidine kinase [Corynebacterium jeikeium ATCC 43734] Length=432 Score = 340 bits (872), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 190/381 (50%), Positives = 252/381 (67%), Gaps = 10/381 (2%) Query 8 LLAGVLSALALAVGGAVGMRLTSRVVEQRQRVAT--EWSG---ITVSQMLQCIVTLMPLG 62 LL G++ + L GA GM + V+ ++ T E G TV+Q+L + P Sbjct 12 LLFGLIVGVCL---GAFGMWAYRKRVKAQRNTHTQRELEGNRVSTVAQVLHFAIQSSPDA 68 Query 63 AAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDV-EFDLSPRKRSATGR 121 AVVD R+VV N RA ELGLV +R L+ +AW+ + ++ E + P R + R Sbjct 69 VAVVDRKRNVVLSNPRAHELGLVHERNLNAEAWKMVERVFADQEPRELNFLPPPRRSN-R 127 Query 122 SGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAE 181 ++V G +LLS D RFAVV+ D S+ RME+ARRDFVANVSHELKTPVGA++LL E Sbjct 128 PVIAVAGQVQLLSLADDRFAVVYATDDSESVRMESARRDFVANVSHELKTPVGAISLLVE 187 Query 182 ALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEA 241 L++ DD E V F K+++E R+ M+ ELI LS+LQGAE LP++ + +D ++ +A Sbjct 188 TLMSVRDDEEAVEYFGSKLIVEVRRMNQMITELISLSKLQGAESLPDLEVLSIDKVIEDA 247 Query 242 ISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRR 301 I R ++AA+ +I++ D S V GD+ LLVT++ANL++NAI YSP GS VSISR Sbjct 248 IDRCRLAAEARNIDLVKDGRSGAMVKGDKGLLVTSVANLLTNAINYSPEGSPVSISREAD 307 Query 302 GANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIR 361 G N+ I VTDRGIGI+ +DQ+RVFERFFR DKARSR TGG+GLGLAIVKHV ANH GT+ Sbjct 308 GDNVIIRVTDRGIGISQDDQKRVFERFFRVDKARSRDTGGTGLGLAIVKHVMANHGGTVS 367 Query 362 VWSKPGTGSTFTLALPALIEA 382 +WS+ GTGSTFTL LP E Sbjct 368 LWSRLGTGSTFTLELPRFQEG 388 >gi|227541628|ref|ZP_03971677.1| histidine kinase [Corynebacterium glucuronolyticum ATCC 51866] gi|227182596|gb|EEI63568.1| histidine kinase [Corynebacterium glucuronolyticum ATCC 51866] Length=414 Score = 339 bits (870), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 189/375 (51%), Positives = 252/375 (68%), Gaps = 8/375 (2%) Query 33 VEQRQRVA---TEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQ 89 + +R R+A +E TVSQ+L + P+G A+VD +R+VV N A +GL+ +R+ Sbjct 27 IARRTRIARTLSEPRVTTVSQVLHLAIQGAPVGVAIVDANREVVLSNASAHTMGLIHERR 86 Query 90 LDDQAWRAARQALG-GEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQ 148 + + W A+ L E+ DL +R+ R + L+ D RF +V+ DQ Sbjct 87 VAQEIWDLAQDVLADKEEHSLDLRAPRRAGKSRV-TDIRVVVAPLTLTDDRFVIVYATDQ 145 Query 149 SDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLG 208 S+ RME ARRDFVANVSHELKTPVG +ALLAEALL S DD E+V F EK+ E+ RLG Sbjct 146 SEAVRMEHARRDFVANVSHELKTPVGGIALLAEALLESIDDPESVDYFGEKLYGESRRLG 205 Query 209 DMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLG 268 DM+ ELI LS+LQGAE LP++T V VD +V EAI+R V A+NA I + + + VLG Sbjct 206 DMITELISLSKLQGAEALPDLTPVLVDDVVDEAINRTTVQAENASIRLNRGVRTGVYVLG 265 Query 269 DQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGAN-IEIAVTDRGIGIAPEDQERVFER 327 D LLVTA+ NL++NAI YSP + V+++++ A+ I I VTDRGIGI+ EDQ+RVFER Sbjct 266 DFNLLVTAVTNLIANAINYSPAETPVTVTQKVVSADIIHIRVTDRGIGISTEDQQRVFER 325 Query 328 FFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDE 387 FFR DKARSR+TGG+GLGLAIVKHVAANH GT+++WS+P TGSTFT+ LP +E Sbjct 326 FFRVDKARSRSTGGTGLGLAIVKHVAANHGGTVKLWSRPSTGSTFTIELPIYRPGEEKEE 385 Query 388 RPEQAREPELRSNRS 402 P AR+ ++ NR+ Sbjct 386 LPHPARKQDV--NRT 398 Lambda K H 0.318 0.132 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 819347350176 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40