BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv0491

Length=227
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15607632|ref|NP_215005.1|  two component sensory transduction ...   449    1e-124
gi|15839882|ref|NP_334919.1|  DNA-binding response regulator RegX...   449    1e-124
gi|121636407|ref|YP_976630.1|  two component sensory transduction...   447    4e-124
gi|158429258|pdb|2OQR|A  Chain A, The Structure Of The Response R...   447    7e-124
gi|224988879|ref|YP_002643566.1|  two component sensory transduct...   444    3e-123
gi|41410081|ref|NP_962917.1|  RegX3 [Mycobacterium avium subsp. p...   444    3e-123
gi|118619653|ref|YP_907985.1|  two component sensory transduction...   444    5e-123
gi|254821074|ref|ZP_05226075.1|  DNA-binding response regulator [...   443    9e-123
gi|296168092|ref|ZP_06850158.1|  DNA-binding response regulator [...   443    1e-122
gi|342859008|ref|ZP_08715662.1|  DNA-binding response regulator [...   443    1e-122
gi|240173513|ref|ZP_04752171.1|  two-component sensory transducti...   439    1e-121
gi|120401846|ref|YP_951675.1|  two component transcriptional regu...   425    3e-117
gi|254230838|ref|ZP_04924165.1|  two component sensory transducti...   424    4e-117
gi|108797641|ref|YP_637838.1|  two component transcriptional regu...   423    9e-117
gi|315442360|ref|YP_004075239.1|  response regulator with CheY-li...   422    2e-116
gi|145220688|ref|YP_001131366.1|  two component transcriptional r...   421    5e-116
gi|169631126|ref|YP_001704775.1|  sensory transduction protein Re...   416    1e-114
gi|333989119|ref|YP_004521733.1|  two-component sensory transduct...   408    4e-112
gi|18202894|sp|Q9F868.1|REGX3_MYCS2  RecName: Full=Sensory transd...   404    5e-111
gi|111019061|ref|YP_702033.1|  response regulator, two-component ...   400    6e-110
gi|325674080|ref|ZP_08153770.1|  DNA-binding response regulator [...   399    1e-109
gi|226305111|ref|YP_002765069.1|  two-component response regulato...   398    3e-109
gi|54027160|ref|YP_121402.1|  putative two-component system respo...   397    6e-109
gi|296138387|ref|YP_003645630.1|  winged helix family two compone...   397    7e-109
gi|118470709|ref|YP_885340.1|  DNA-binding response regulator Reg...   397    9e-109
gi|312141110|ref|YP_004008446.1|  two component system response r...   392    2e-107
gi|289748982|ref|ZP_06508360.1|  two component system sensor prot...   392    3e-107
gi|262200993|ref|YP_003272201.1|  response regulator receiver [Go...   389    2e-106
gi|333918302|ref|YP_004491883.1|  Two-component response regulato...   388    3e-106
gi|317507256|ref|ZP_07965002.1|  response regulator receiver doma...   383    1e-104
gi|296394042|ref|YP_003658926.1|  transcriptional regulator [Segn...   383    1e-104
gi|256380732|ref|YP_003104392.1|  winged helix family two compone...   382    2e-104
gi|134103391|ref|YP_001109052.1|  two-component response regulato...   375    3e-102
gi|325000981|ref|ZP_08122093.1|  two component transcriptional re...   375    3e-102
gi|296118440|ref|ZP_06837019.1|  DNA-binding response regulator R...   375    3e-102
gi|300782393|ref|YP_003762684.1|  two-component system response r...   374    8e-102
gi|302523820|ref|ZP_07276162.1|  phosphate regulon transcriptiona...   374    9e-102
gi|257054346|ref|YP_003132178.1|  response regulator with CheY-li...   373    1e-101
gi|15828317|ref|NP_302580.1|  two-component system response regul...   372    2e-101
gi|343925947|ref|ZP_08765462.1|  two-component response regulator...   369    1e-100
gi|319949621|ref|ZP_08023661.1|  two-component response regulator...   368    3e-100
gi|326383061|ref|ZP_08204750.1|  response regulator receiver [Gor...   367    5e-100
gi|38233005|ref|NP_938772.1|  putative two component system respo...   367    7e-100
gi|258655036|ref|YP_003204192.1|  winged helix family two compone...   365    3e-99 
gi|227505097|ref|ZP_03935146.1|  response regulator [Corynebacter...   365    4e-99 
gi|300857676|ref|YP_003782659.1|  two-component system transcript...   363    1e-98 
gi|337289923|ref|YP_004628944.1|  two-component system transcript...   360    8e-98 
gi|227832117|ref|YP_002833824.1|  two-component system response r...   359    2e-97 
gi|331699380|ref|YP_004335619.1|  winged helix family two compone...   358    4e-97 
gi|227541629|ref|ZP_03971678.1|  response regulator [Corynebacter...   356    1e-96 


>gi|15607632|ref|NP_215005.1| two component sensory transduction protein RegX3 [Mycobacterium 
tuberculosis H37Rv]
 gi|31791671|ref|NP_854164.1| two component sensory transduction protein RegX3 [Mycobacterium 
bovis AF2122/97]
 gi|148660258|ref|YP_001281781.1| two component sensory transduction protein RegX3 [Mycobacterium 
tuberculosis H37Ra]
 54 more sequence titles
 Length=227

 Score =  449 bits (1155),  Expect = 1e-124, Method: Compositional matrix adjust.
 Identities = 227/227 (100%), Positives = 227/227 (100%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|15839882|ref|NP_334919.1| DNA-binding response regulator RegX3 [Mycobacterium tuberculosis 
CDC1551]
 gi|308231563|ref|ZP_07412927.2| two component system sensor protein regX3 [Mycobacterium tuberculosis 
SUMu001]
 gi|308370423|ref|ZP_07421449.2| putative response regulator receiver domain protein [Mycobacterium 
tuberculosis SUMu003]
 14 more sequence titles
 Length=230

 Score =  449 bits (1155),  Expect = 1e-124, Method: Compositional matrix adjust.
 Identities = 227/227 (100%), Positives = 227/227 (100%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
Sbjct  4    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  63

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  64   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  123

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  124  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  183

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  184  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  230


>gi|121636407|ref|YP_976630.1| two component sensory transduction protein RegX3 [Mycobacterium 
bovis BCG str. Pasteur 1173P2]
 gi|2190436|emb|CAA73956.1| RegX3 [Mycobacterium bovis BCG]
 gi|121492054|emb|CAL70517.1| Two component sensory transduction protein regX3 (probably luxR-family) 
[Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|341600423|emb|CCC63093.1| Two component sensory transduction protein regX3 (probably luxR-family) 
[Mycobacterium bovis BCG str. Moreau RDJ]
Length=227

 Score =  447 bits (1151),  Expect = 4e-124, Method: Compositional matrix adjust.
 Identities = 226/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPL FLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|158429258|pdb|2OQR|A Chain A, The Structure Of The Response Regulator Regx3 From Mycobacterium 
Tuberculosis
Length=230

 Score =  447 bits (1149),  Expect = 7e-124, Method: Compositional matrix adjust.
 Identities = 226/226 (100%), Positives = 226/226 (100%), Gaps = 0/226 (0%)

Query  2    TSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGT  61
            TSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGT
Sbjct  5    TSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGT  64

Query  62   DVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD  121
            DVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD
Sbjct  65   DVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD  124

Query  122  DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDR  181
            DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDR
Sbjct  125  DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDR  184

Query  182  VWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            VWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  185  VWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  230


>gi|224988879|ref|YP_002643566.1| two component sensory transduction protein [Mycobacterium bovis 
BCG str. Tokyo 172]
 gi|224771992|dbj|BAH24798.1| two component sensory transduction protein [Mycobacterium bovis 
BCG str. Tokyo 172]
Length=227

 Score =  444 bits (1143),  Expect = 3e-123, Method: Compositional matrix adjust.
 Identities = 225/227 (99%), Positives = 225/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPL FLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLTFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTV GLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVCGLGYKLEG  227


>gi|41410081|ref|NP_962917.1| RegX3 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118466224|ref|YP_883789.1| DNA-binding response regulator [Mycobacterium avium 104]
 gi|254777097|ref|ZP_05218613.1| DNA-binding response regulator [Mycobacterium avium subsp. avium 
ATCC 25291]
 gi|41398914|gb|AAS06533.1| RegX3 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118167511|gb|ABK68408.1| DNA-binding response regulator [Mycobacterium avium 104]
 gi|336460462|gb|EGO39358.1| response regulator with CheY-like receiver domain-containing 
protein [Mycobacterium avium subsp. paratuberculosis S397]
Length=227

 Score =  444 bits (1143),  Expect = 3e-123, Method: Compositional matrix adjust.
 Identities = 225/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDG AALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGSAALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSE+SDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEISDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|118619653|ref|YP_907985.1| two component sensory transduction protein RegX3 [Mycobacterium 
ulcerans Agy99]
 gi|183980840|ref|YP_001849131.1| two-component sensory transduction protein RegX3 [Mycobacterium 
marinum M]
 gi|118571763|gb|ABL06514.1| two component sensory transduction protein RegX3 [Mycobacterium 
ulcerans Agy99]
 gi|183174166|gb|ACC39276.1| two-component sensory transduction protein RegX3 [Mycobacterium 
marinum M]
Length=227

 Score =  444 bits (1142),  Expect = 5e-123, Method: Compositional matrix adjust.
 Identities = 224/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDR+GADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSE+SDGVLESGPVRMDVERHVVSVNGD ITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEVSDGVLESGPVRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|254821074|ref|ZP_05226075.1| DNA-binding response regulator [Mycobacterium intracellulare 
ATCC 13950]
Length=227

 Score =  443 bits (1139),  Expect = 9e-123, Method: Compositional matrix adjust.
 Identities = 224/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDG AALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGSAALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            +DDSE+SDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  EDDSEISDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|296168092|ref|ZP_06850158.1| DNA-binding response regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295896899|gb|EFG76527.1| DNA-binding response regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=227

 Score =  443 bits (1139),  Expect = 1e-122, Method: Compositional matrix adjust.
 Identities = 224/227 (99%), Positives = 225/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDG AALAEFDR GADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGQAALAEFDRGGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSE+SDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEISDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|342859008|ref|ZP_08715662.1| DNA-binding response regulator [Mycobacterium colombiense CECT 
3035]
 gi|342133249|gb|EGT86452.1| DNA-binding response regulator [Mycobacterium colombiense CECT 
3035]
Length=227

 Score =  443 bits (1139),  Expect = 1e-122, Method: Compositional matrix adjust.
 Identities = 224/227 (99%), Positives = 225/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDG AALAEFDR GADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGSAALAEFDRGGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSE+SDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDSEISDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|240173513|ref|ZP_04752171.1| two-component sensory transduction protein RegX3 [Mycobacterium 
kansasii ATCC 12478]
Length=227

 Score =  439 bits (1129),  Expect = 1e-121, Method: Compositional matrix adjust.
 Identities = 220/227 (97%), Positives = 225/227 (99%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT+VLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDR+GADIVLLDLMLPGMSG
Sbjct  1    MTNVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDD+E SDG+LESGPVRMDVERHVVSVNG+ ITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  DDDAESSDGILESGPVRMDVERHVVSVNGEVITLPLKEFDLLEYLMRNSGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|120401846|ref|YP_951675.1| two component transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119954664|gb|ABM11669.1| two component transcriptional regulator, winged helix family 
[Mycobacterium vanbaalenii PYR-1]
Length=228

 Score =  425 bits (1092),  Expect = 3e-117, Method: Compositional matrix adjust.
 Identities = 215/228 (95%), Positives = 222/228 (98%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVV DGP+ALAEF+RAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVADGPSALAEFERAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR+RSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGS  120

Query  121  D-DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            D DD+ + DGVLE+GPVRMDVERHVVSVNG +ITLPLKEFDLLEYLMRNSGRVLTRGQLI
Sbjct  121  DADDAGIGDGVLEAGPVRMDVERHVVSVNGQSITLPLKEFDLLEYLMRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  228


>gi|254230838|ref|ZP_04924165.1| two component sensory transduction protein regX3 [Mycobacterium 
tuberculosis C]
 gi|124599897|gb|EAY58907.1| two component sensory transduction protein regX3 [Mycobacterium 
tuberculosis C]
Length=250

 Score =  424 bits (1091),  Expect = 4e-117, Method: Compositional matrix adjust.
 Identities = 215/215 (100%), Positives = 215/215 (100%), Gaps = 0/215 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG
Sbjct  4    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  63

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  64   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  123

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  124  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  183

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHL  215
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHL
Sbjct  184  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHL  218


>gi|108797641|ref|YP_637838.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119866728|ref|YP_936680.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|126433265|ref|YP_001068956.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 gi|108768060|gb|ABG06782.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. MCS]
 gi|119692817|gb|ABL89890.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. KMS]
 gi|126233065|gb|ABN96465.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. JLS]
Length=228

 Score =  423 bits (1088),  Expect = 9e-117, Method: Compositional matrix adjust.
 Identities = 216/228 (95%), Positives = 220/228 (97%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE TVV DGP+ALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFETTVVADGPSALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGT  120

Query  121  D-DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            D DD  + DGVLE+GPVRMDVERHVVSVNG +ITLPLKEFDLLEYLMRNSGRVLTRGQLI
Sbjct  121  DVDDPGVPDGVLEAGPVRMDVERHVVSVNGQSITLPLKEFDLLEYLMRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  228


>gi|315442360|ref|YP_004075239.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
 gi|315260663|gb|ADT97404.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
Length=228

 Score =  422 bits (1084),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 214/228 (94%), Positives = 221/228 (97%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE TVVTDGP+ALAEF+RAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALAEFERAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR+RSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  121  D-DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            D DD  ++DGVLE+GPVRMDVERHVVSVNG  ITLPLKEFDLLEYLMRNSGRVLTRGQLI
Sbjct  121  DTDDVGVADGVLEAGPVRMDVERHVVSVNGSPITLPLKEFDLLEYLMRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE+DPANPVHLVTVRGLGYKLEG
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIESDPANPVHLVTVRGLGYKLEG  228


>gi|145220688|ref|YP_001131366.1| two component transcriptional regulator [Mycobacterium gilvum 
PYR-GCK]
 gi|145213174|gb|ABP42578.1| two component transcriptional regulator, winged helix family 
[Mycobacterium gilvum PYR-GCK]
Length=228

 Score =  421 bits (1081),  Expect = 5e-116, Method: Compositional matrix adjust.
 Identities = 214/228 (94%), Positives = 221/228 (97%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE TVVTDGP+ALAEF+RAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALAEFERAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR+RSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  121  D-DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            D DD  ++DGVLE+GPVRMDVERHVVSVNG  ITLPLKEFDLLEYLMRNSGRVLTRGQLI
Sbjct  121  DADDLGVADGVLEAGPVRMDVERHVVSVNGAPITLPLKEFDLLEYLMRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE+DPANPVHLVTVRGLGYKLEG
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIESDPANPVHLVTVRGLGYKLEG  228


>gi|169631126|ref|YP_001704775.1| sensory transduction protein RegX3 [Mycobacterium abscessus ATCC 
19977]
 gi|169243093|emb|CAM64121.1| Sensory transduction protein RegX3 [Mycobacterium abscessus]
Length=228

 Score =  416 bits (1069),  Expect = 1e-114, Method: Compositional matrix adjust.
 Identities = 209/228 (92%), Positives = 219/228 (97%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDE+SLADPLAFLLRKEGFEAT+V DGP+ALAEF+RAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEDSLADPLAFLLRKEGFEATIVNDGPSALAEFERAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRA+SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRAKSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGS  120

Query  121  DDDSEMS-DGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            D +   S DGVLE+GPVRMDV+RH VSVNG+ ITLPLKEFDLLEYL+RNSGRVLTRGQLI
Sbjct  121  DSEETASGDGVLEAGPVRMDVDRHTVSVNGEAITLPLKEFDLLEYLIRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  228


>gi|333989119|ref|YP_004521733.1| two-component sensory transduction protein RegX3 [Mycobacterium 
sp. JDM601]
 gi|333485087|gb|AEF34479.1| two-component sensory transduction protein RegX3 [Mycobacterium 
sp. JDM601]
Length=227

 Score =  408 bits (1048),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 214/227 (95%), Positives = 220/227 (97%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFEATVVTDG AALAEFDR+GADIVLLDLMLPGMSG
Sbjct  1    MTHVLIVEDEESLADPLAFLLRKEGFEATVVTDGTAALAEFDRSGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            DD+  + +GVLESGPVRMDVERHVV VNG+ ITLPLKEFDLLEYLMRN+GRVLTRGQLID
Sbjct  121  DDEGGVGEGVLESGPVRMDVERHVVMVNGEQITLPLKEFDLLEYLMRNTGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227


>gi|18202894|sp|Q9F868.1|REGX3_MYCS2 RecName: Full=Sensory transduction protein regX3
 gi|9964001|gb|AAG09797.1|AF258346_2 response regulator RegX3 [Mycobacterium smegmatis str. MC2 155]
Length=228

 Score =  404 bits (1038),  Expect = 5e-111, Method: Compositional matrix adjust.
 Identities = 212/228 (93%), Positives = 219/228 (97%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFEATVV DGP+ALAEF+R+GADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVGDGPSALAEFERSGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR-G  119
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR  
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  120  GDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
             +DD+   DGVLE+GPVRMDVERHVVSVNG+ ITLPLKEFDLLEYLMRNSGRVLTRGQLI
Sbjct  121  DNDDAGADDGVLEAGPVRMDVERHVVSVNGEPITLPLKEFDLLEYLMRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE DPANPVHLVTVRGLGYKLEG
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG  228


>gi|111019061|ref|YP_702033.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
 gi|226361154|ref|YP_002778932.1| two-component response regulator RegX3 [Rhodococcus opacus B4]
 gi|110818591|gb|ABG93875.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
 gi|226239639|dbj|BAH49987.1| two-component response regulator RegX3 [Rhodococcus opacus B4]
Length=229

 Score =  400 bits (1029),  Expect = 6e-110, Method: Compositional matrix adjust.
 Identities = 202/229 (89%), Positives = 213/229 (94%), Gaps = 2/229 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE T+V DGP+ALAEFDRAGADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFETTIVGDGPSALAEFDRAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR+RS VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRSRSGVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGV  120

Query  121  DDDSEMSD--GVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            D + +++    VLE+GPVRMDVERHVV VNG+ +TLPLKEFDLLEYL+RNSGRVLTRGQL
Sbjct  121  DSELDVAQDSAVLEAGPVRMDVERHVVQVNGEAVTLPLKEFDLLEYLLRNSGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            IDRVWGADYVGDTKTLDVHVKRLRSKIE DPA P HLVTVRGLGYKLE 
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIETDPAKPEHLVTVRGLGYKLEA  229


>gi|325674080|ref|ZP_08153770.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
 gi|325555345|gb|EGD25017.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
Length=229

 Score =  399 bits (1026),  Expect = 1e-109, Method: Compositional matrix adjust.
 Identities = 200/228 (88%), Positives = 215/228 (95%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE TVV DGP+ALAEF+R+GADIVLLD+MLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFETTVVGDGPSALAEFERSGADIVLLDVMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRA+SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRAKSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  121  DDD--SEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            D++  +++ DGVL +GPVRMDVERH+V VNGD +TLPLKEFDLLEYL+RNSGRVLTRGQL
Sbjct  121  DNEAATDVDDGVLAAGPVRMDVERHLVHVNGDPVTLPLKEFDLLEYLLRNSGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLR+KIE DP  P HLVTVRGLGYKLE
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRAKIEGDPGKPKHLVTVRGLGYKLE  228


>gi|226305111|ref|YP_002765069.1| two-component response regulator RegX3 [Rhodococcus erythropolis 
PR4]
 gi|229490687|ref|ZP_04384525.1| response regulator, two-component system [Rhodococcus erythropolis 
SK121]
 gi|226184226|dbj|BAH32330.1| two-component response regulator RegX3 [Rhodococcus erythropolis 
PR4]
 gi|229322507|gb|EEN88290.1| response regulator, two-component system [Rhodococcus erythropolis 
SK121]
Length=229

 Score =  398 bits (1023),  Expect = 3e-109, Method: Compositional matrix adjust.
 Identities = 199/229 (87%), Positives = 216/229 (95%), Gaps = 2/229 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE T+V DGP+ALAEFDR+GADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFETTIVNDGPSALAEFDRSGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCK LR+RS VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKALRSRSGVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGV  120

Query  121  DDDSEMS--DGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            +++++++  +GVLE+GPVRMDVERHVV V G+ +TLPLKEFDLLEYL+RNSGRVLTRGQL
Sbjct  121  ENEADLASDNGVLEAGPVRMDVERHVVQVAGNPVTLPLKEFDLLEYLLRNSGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            IDRVWGADYVGDTKTLDVHVKRLRSKIE+DPA P HLVTVRGLGYKLE 
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIESDPAKPEHLVTVRGLGYKLEA  229


>gi|54027160|ref|YP_121402.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
 gi|54018668|dbj|BAD60038.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
Length=229

 Score =  397 bits (1020),  Expect = 6e-109, Method: Compositional matrix adjust.
 Identities = 203/228 (90%), Positives = 209/228 (92%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE TVV DGP+ALAEFDR+GADIVLLDLMLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEVTVVGDGPSALAEFDRSGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR RS VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRTRSGVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  121  DD--DSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
             D  D     GVLE+GPVRMDV+RH V VNG  +TLPLKEFDLLEYL+RNSGRVLTRGQL
Sbjct  121  GDELDGNGESGVLEAGPVRMDVDRHTVMVNGKPVTLPLKEFDLLEYLLRNSGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSKIEADPA P HLVTVRGLGYKLE
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPAKPEHLVTVRGLGYKLE  228


>gi|296138387|ref|YP_003645630.1| winged helix family two component transcriptional regulator [Tsukamurella 
paurometabola DSM 20162]
 gi|296026521|gb|ADG77291.1| two component transcriptional regulator, winged helix family 
[Tsukamurella paurometabola DSM 20162]
Length=229

 Score =  397 bits (1020),  Expect = 7e-109, Method: Compositional matrix adjust.
 Identities = 204/228 (90%), Positives = 209/228 (92%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFE TVVTDG  AL  FD AGADIVLLDLMLPGMSG
Sbjct  1    MTHVLIVEDEESLADPLAFLLRKEGFETTVVTDGAEALRHFDSAGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  121  DD--DSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            D      + DGVLE GPVRMDVERHVV+V G+ +TLPLKEFDLLEYL+RNSGRVLTRGQL
Sbjct  121  DTAGGEGLDDGVLEGGPVRMDVERHVVTVAGEAVTLPLKEFDLLEYLLRNSGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANP HLVTVRGLGYKLE
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPKHLVTVRGLGYKLE  228


>gi|118470709|ref|YP_885340.1| DNA-binding response regulator RegX3 [Mycobacterium smegmatis 
str. MC2 155]
 gi|118171996|gb|ABK72892.1| DNA-binding response regulator RegX3 [Mycobacterium smegmatis 
str. MC2 155]
Length=225

 Score =  397 bits (1019),  Expect = 9e-109, Method: Compositional matrix adjust.
 Identities = 208/225 (93%), Positives = 216/225 (96%), Gaps = 1/225 (0%)

Query  4    VLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDV  63
            +LIVEDEESLADPLAFLLRKEGFEATVV DGP+ALAEF+R+GADIVLLDLMLPGMSGTDV
Sbjct  1    MLIVEDEESLADPLAFLLRKEGFEATVVGDGPSALAEFERSGADIVLLDLMLPGMSGTDV  60

Query  64   CKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR-GGDD  122
            CKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR   +D
Sbjct  61   CKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGADND  120

Query  123  DSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRV  182
            D+   DGVLE+GPVRMDVERHVVSVNG+ ITLPLKEFDLLEYLMRNSGRVLTRGQLIDRV
Sbjct  121  DAGADDGVLEAGPVRMDVERHVVSVNGEPITLPLKEFDLLEYLMRNSGRVLTRGQLIDRV  180

Query  183  WGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            WGADYVGDTKTLDVHVKRLRSKIE DPANPVHLVTVRGLGYKLEG
Sbjct  181  WGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG  225


>gi|312141110|ref|YP_004008446.1| two component system response regulator [Rhodococcus equi 103S]
 gi|311890449|emb|CBH49767.1| two component system response regulator [Rhodococcus equi 103S]
Length=226

 Score =  392 bits (1007),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 196/225 (88%), Positives = 212/225 (95%), Gaps = 2/225 (0%)

Query  4    VLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDV  63
            +LIVEDEESLADPLAFLLRKEGFE TVV DGP+ALAEF+R+GADIVLLD+MLPGMSGTDV
Sbjct  1    MLIVEDEESLADPLAFLLRKEGFETTVVGDGPSALAEFERSGADIVLLDVMLPGMSGTDV  60

Query  64   CKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDD  123
            CKQLRA+SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG D++
Sbjct  61   CKQLRAKSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGADNE  120

Query  124  --SEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDR  181
              +++ DGVL +GPVRMDVERH+V VNGD +TLPLKEFDLLEYL+RNSGRVLTRGQLIDR
Sbjct  121  AATDVDDGVLAAGPVRMDVERHLVHVNGDPVTLPLKEFDLLEYLLRNSGRVLTRGQLIDR  180

Query  182  VWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            VWGADYVGDTKTLDVHVKRLR+KIE DP  P HLVTVRGLGYKLE
Sbjct  181  VWGADYVGDTKTLDVHVKRLRAKIEGDPGKPKHLVTVRGLGYKLE  225


>gi|289748982|ref|ZP_06508360.1| two component system sensor protein regX3 [Mycobacterium tuberculosis 
T92]
 gi|289689569|gb|EFD56998.1| two component system sensor protein regX3 [Mycobacterium tuberculosis 
T92]
Length=198

 Score =  392 bits (1006),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 197/198 (99%), Positives = 198/198 (100%), Gaps = 0/198 (0%)

Query  30   VVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVV  89
            +VTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVV
Sbjct  1    MVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVV  60

Query  90   GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNG  149
            GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNG
Sbjct  61   GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNG  120

Query  150  DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADP  209
            DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADP
Sbjct  121  DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADP  180

Query  210  ANPVHLVTVRGLGYKLEG  227
            ANPVHLVTVRGLGYKLEG
Sbjct  181  ANPVHLVTVRGLGYKLEG  198


>gi|262200993|ref|YP_003272201.1| response regulator receiver [Gordonia bronchialis DSM 43247]
 gi|262084340|gb|ACY20308.1| response regulator receiver [Gordonia bronchialis DSM 43247]
Length=228

 Score =  389 bits (999),  Expect = 2e-106, Method: Compositional matrix adjust.
 Identities = 194/228 (86%), Positives = 209/228 (92%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFEA+VV DG  AL+ FDR   DIVLLDLMLPGMSG
Sbjct  1    MTHVLIVEDEESLADPLAFLLRKEGFEASVVNDGAQALSTFDRVSPDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            T++CK LR RSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TEICKALRTRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  D-DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            D  + ++  G+LE+GPVRMDVERH+V+VNG+ ITLPLKEFDLLEYL+RN+GRVLTRGQLI
Sbjct  121  DLAEEDLDIGILEAGPVRMDVERHIVAVNGEQITLPLKEFDLLEYLLRNAGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE DPANP HL+TVRGLGYKLE 
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEPDPANPKHLITVRGLGYKLEA  228


>gi|333918302|ref|YP_004491883.1| Two-component response regulator RegX3 [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333480523|gb|AEF39083.1| Two-component response regulator RegX3 [Amycolicicoccus subflavus 
DQS3-9A1]
Length=228

 Score =  388 bits (997),  Expect = 3e-106, Method: Compositional matrix adjust.
 Identities = 195/227 (86%), Positives = 211/227 (93%), Gaps = 1/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTSVLIVEDEESLADPLAFLLRKEGFE T+  DGPAAL  FD AGADIVLLD+MLPGMSG
Sbjct  1    MTSVLIVEDEESLADPLAFLLRKEGFEVTIAADGPAALDSFDNAGADIVLLDIMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            T+VCKQLRARS+VPVIMVTARDSEIDKVVGLE+GADDYVTKPYS+RELIARIRAVLRRG 
Sbjct  61   TEVCKQLRARSTVPVIMVTARDSEIDKVVGLEIGADDYVTKPYSSRELIARIRAVLRRGV  120

Query  121  DDDSEMS-DGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            + ++E S D VLE+GPVRMDV+RH+V V+G ++TLPLKEFDLLEYL+RNSGRVLTRGQLI
Sbjct  121  EPEAEPSGDTVLEAGPVRMDVDRHIVQVSGASVTLPLKEFDLLEYLLRNSGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            DRVWGADYVGDTKTLDVHVKRLRSKIE DPA P HLVTVRGLGYKLE
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIELDPAKPRHLVTVRGLGYKLE  227


>gi|317507256|ref|ZP_07965002.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
 gi|316254450|gb|EFV13774.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
Length=228

 Score =  383 bits (983),  Expect = 1e-104, Method: Compositional matrix adjust.
 Identities = 193/228 (85%), Positives = 204/228 (90%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFE  +  DGP AL EFDR GADIVLLDLMLPGM G
Sbjct  1    MTRVLIVEDEESLADPLAFLLRKEGFETVIAGDGPTALTEFDRTGADIVLLDLMLPGMGG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
             DVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSAREL ARIRAVLRRG 
Sbjct  61   NDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELTARIRAVLRRGQ  120

Query  121  DDDSEMS-DGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            + +SE S DG LE+GP+++DV+RH+VSV+G  +TLPLKEFDLLEYLMRN GRVLTRGQLI
Sbjct  121  EAESETSLDGALEAGPIKLDVDRHLVSVHGKQVTLPLKEFDLLEYLMRNRGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE DPA P  LVTVRGLGYKLE 
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEDDPAKPERLVTVRGLGYKLEA  228


>gi|296394042|ref|YP_003658926.1| transcriptional regulator [Segniliparus rotundus DSM 44985]
 gi|296181189|gb|ADG98095.1| two component transcriptional regulator, winged helix family 
[Segniliparus rotundus DSM 44985]
Length=228

 Score =  383 bits (983),  Expect = 1e-104, Method: Compositional matrix adjust.
 Identities = 194/228 (86%), Positives = 206/228 (91%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFE  +  DGPAAL EFDR+GADIVLLDLMLPGM G
Sbjct  1    MTRVLIVEDEESLADPLAFLLRKEGFETVIAGDGPAALTEFDRSGADIVLLDLMLPGMGG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
             DVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSAREL ARIRAVLRRG 
Sbjct  61   NDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELTARIRAVLRRGQ  120

Query  121  DDDSEMS-DGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
            + DSE S +GVLE+GP+++DV+RH+VSV+   +TLPLKEFDLLEYLMRN GRVLTRGQLI
Sbjct  121  EADSETSAEGVLEAGPIKLDVDRHLVSVHSKHVTLPLKEFDLLEYLMRNRGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE DPA P  LVTVRGLGYKLE 
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEDDPAKPDRLVTVRGLGYKLEA  228


>gi|256380732|ref|YP_003104392.1| winged helix family two component transcriptional regulator [Actinosynnema 
mirum DSM 43827]
 gi|255925035|gb|ACU40546.1| two component transcriptional regulator, winged helix family 
[Actinosynnema mirum DSM 43827]
Length=226

 Score =  382 bits (980),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 192/226 (85%), Positives = 203/226 (90%), Gaps = 1/226 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAFLLRKEGF A +   GP AL EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFLLRKEGFTAALAATGPEALEEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR RS+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKQLRQRSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            + + E+   VLE+GPVRMDVERHVV+VNG+ + LPLKEFDLLEYL+RN GRVLTRGQLID
Sbjct  121  ESE-ELLPQVLEAGPVRMDVERHVVTVNGEEVALPLKEFDLLEYLLRNVGRVLTRGQLID  179

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            RVWGADYVGDTKTLDVHVKRLRSK+E DPA P HLVTVRGLGYK E
Sbjct  180  RVWGADYVGDTKTLDVHVKRLRSKVEPDPATPRHLVTVRGLGYKFE  225


>gi|134103391|ref|YP_001109052.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
 gi|291004390|ref|ZP_06562363.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133916014|emb|CAM06127.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
Length=226

 Score =  375 bits (963),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 190/226 (85%), Positives = 204/226 (91%), Gaps = 1/226 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAFLLRKEGF A V T G  AL EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFLLRKEGFTAAVATTGQEALEEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR RS+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIAR+RAVLRRGG
Sbjct  61   TDVCKQLRQRSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            + + +M   VLE+GPVRMDVERHVV+V+G+ ++LPLKEFDLLEYL+RN GRVLTRGQLID
Sbjct  121  EAE-DMLPQVLEAGPVRMDVERHVVTVSGEEVSLPLKEFDLLEYLLRNVGRVLTRGQLID  179

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            RVWGADYVGDTKTLDVHVKRLRSK+E DPA P +LVTVRGLGYK E
Sbjct  180  RVWGADYVGDTKTLDVHVKRLRSKLEPDPAEPRYLVTVRGLGYKFE  225


>gi|325000981|ref|ZP_08122093.1| two component transcriptional regulator, winged helix family 
protein [Pseudonocardia sp. P1]
Length=229

 Score =  375 bits (962),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 187/228 (83%), Positives = 204/228 (90%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAF+LRKEGF   V  +G  AL+EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFMLRKEGFTTAVAANGNDALSEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCK LR+RS+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIAR+RAVLRRGG
Sbjct  61   TDVCKALRSRSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRGG  120

Query  121  D--DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            +   ++E  +G+LE+GPVRMDVERHVVSVNGD + LPLKEFDLLEYL+RN GRVLTR QL
Sbjct  121  EATGETESGNGILEAGPVRMDVERHVVSVNGDDVPLPLKEFDLLEYLLRNVGRVLTRAQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSK+E DP+ P HLVTVRGLGYK +
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKVEDDPSTPKHLVTVRGLGYKFD  228


>gi|296118440|ref|ZP_06837019.1| DNA-binding response regulator RegX3 [Corynebacterium ammoniagenes 
DSM 20306]
 gi|295968581|gb|EFG81827.1| DNA-binding response regulator RegX3 [Corynebacterium ammoniagenes 
DSM 20306]
Length=230

 Score =  375 bits (962),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 188/229 (83%), Positives = 204/229 (90%), Gaps = 3/229 (1%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT++LIVEDEESLADPLAFLLRKEGFE  V  DG  ALAEF+R   DIVLLDLMLPGMSG
Sbjct  1    MTTILIVEDEESLADPLAFLLRKEGFEPIVAHDGKTALAEFERHDVDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRA SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYS+RELIARIRAVLRRGG
Sbjct  61   TDVCKQLRATSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGG  120

Query  121  DD---DSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQ  177
            +    D E  D +LE G VRMDVERH VSV+G+ +++PLKEFDLLEYL+RN+GRVLTRGQ
Sbjct  121  EAAEVDEEFEDQILEGGRVRMDVERHTVSVDGEPVSMPLKEFDLLEYLLRNTGRVLTRGQ  180

Query  178  LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            LIDR+WGADYVGDTKTLDVHVKRLRSKIEA+P+ P HLVTVRGLGYK E
Sbjct  181  LIDRIWGADYVGDTKTLDVHVKRLRSKIEAEPSRPQHLVTVRGLGYKYE  229


>gi|300782393|ref|YP_003762684.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
 gi|299791907|gb|ADJ42282.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
 gi|340523760|gb|AEK38965.1| two-component system response regulator [Amycolatopsis mediterranei 
S699]
Length=229

 Score =  374 bits (959),  Expect = 8e-102, Method: Compositional matrix adjust.
 Identities = 191/228 (84%), Positives = 203/228 (90%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAFLLRKEGF A V   G AAL EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFLLRKEGFTAAVAGTGQAALEEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR RS+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIAR+RAVLRRGG
Sbjct  61   TDVCKQLRQRSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRGG  120

Query  121  DDDS--EMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            +  S  E++  VL +GPVRMDVERHVV+V+G  ++LPLKEFDLLEYL+RN GRVLTRGQL
Sbjct  121  EPGSEGELAPLVLSAGPVRMDVERHVVTVDGADVSLPLKEFDLLEYLLRNVGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSKIE DP +P HLVTVRGLGYK E
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIEPDPGSPRHLVTVRGLGYKFE  228


>gi|302523820|ref|ZP_07276162.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. AA4]
 gi|302432715|gb|EFL04531.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. AA4]
Length=229

 Score =  374 bits (959),  Expect = 9e-102, Method: Compositional matrix adjust.
 Identities = 190/228 (84%), Positives = 202/228 (89%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAFLLRKEGF A V   G  AL EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFLLRKEGFTAAVAVTGQQALEEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR RS+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIAR+RAVLRRGG
Sbjct  61   TDVCKQLRQRSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRGG  120

Query  121  D--DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            +   D E++  VL +GPVRMDVERHVV+V+G  ++LPLKEFDLLEYL+RN GRVLTRGQL
Sbjct  121  EPGSDGELAPLVLSAGPVRMDVERHVVTVDGGEVSLPLKEFDLLEYLLRNVGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSKIE DP +P HLVTVRGLGYK E
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIEPDPGSPRHLVTVRGLGYKFE  228


>gi|257054346|ref|YP_003132178.1| response regulator with CheY-like receiver domain-containing 
protein and winged-helix DNA-binding domain-containing protein 
[Saccharomonospora viridis DSM 43017]
 gi|256584218|gb|ACU95351.1| response regulator with CheY-like receiver domain protein and 
winged-helix DNA-binding domain protein [Saccharomonospora 
viridis DSM 43017]
Length=229

 Score =  373 bits (958),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 189/228 (83%), Positives = 200/228 (88%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAFLLRKEGF A + TDG  AL EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFLLRKEGFTAAIATDGQQALEEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVC++LR RSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIAR+RAVLRRGG
Sbjct  61   TDVCRELRQRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRGG  120

Query  121  DD--DSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            D   DS+    VL  GPVRMDVERHVV+VNG  + LPLKEFDLLEYL+RN GRVLTR QL
Sbjct  121  DSSGDSQQEQTVLIGGPVRMDVERHVVTVNGTEVPLPLKEFDLLEYLLRNVGRVLTRNQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSKIE +P +P +LVTVRGLGYK E
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKIEPEPGSPRYLVTVRGLGYKFE  228


>gi|15828317|ref|NP_302580.1| two-component system response regulator [Mycobacterium leprae 
TN]
 gi|221230794|ref|YP_002504210.1| putative two-component system response regulator [Mycobacterium 
leprae Br4923]
 gi|1731206|sp|P54884.1|REGX3_MYCLE RecName: Full=Sensory transduction protein regX3
 gi|467058|gb|AAA17242.1| phoP [Mycobacterium leprae]
 gi|13094010|emb|CAC31956.1| probable two-component system response regulator [Mycobacterium 
leprae]
 gi|219933901|emb|CAR72538.1| probable two-component system response regulator [Mycobacterium 
leprae Br4923]
Length=198

 Score =  372 bits (955),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 188/197 (96%), Positives = 192/197 (98%), Gaps = 0/197 (0%)

Query  30   VVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVV  89
            +VTDGPAALAEFDR+GADIVLLDLMLPGMSGTDV KQLR RSSVPVIMVTARDSEIDKVV
Sbjct  1    MVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVV  60

Query  90   GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEMSDGVLESGPVRMDVERHVVSVNG  149
            GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSE+SDGVLESGP+RMDVERHVVSVNG
Sbjct  61   GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNG  120

Query  150  DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADP  209
              ITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWG DYVGDTKTLDVHVKRLRSKIEADP
Sbjct  121  YAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVGDTKTLDVHVKRLRSKIEADP  180

Query  210  ANPVHLVTVRGLGYKLE  226
            ANPVHLVTVRGLGYKLE
Sbjct  181  ANPVHLVTVRGLGYKLE  197


>gi|343925947|ref|ZP_08765462.1| two-component response regulator RegX3 [Gordonia alkanivorans 
NBRC 16433]
 gi|343764298|dbj|GAA12388.1| two-component response regulator RegX3 [Gordonia alkanivorans 
NBRC 16433]
Length=228

 Score =  369 bits (948),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 188/228 (83%), Positives = 205/228 (90%), Gaps = 1/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFEA++V DG  AL  FDR   DIVLLDLMLPGMSG
Sbjct  1    MTHVLIVEDEESLADPLAFLLRKEGFEASIVNDGAQALPAFDRVSPDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR-G  119
            T++CK LRARS+VPVIMVTARD+EIDKVVGLELGADDYVTKPYSARELIARIRAVLRR  
Sbjct  61   TEICKALRARSNVPVIMVTARDTEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  120  GDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI  179
               D ++  GV+E+GPVRMDVERH V+VNG+ ITLPLKEFDLLEYL+RN+GRVLTRGQLI
Sbjct  121  DAGDDDLDLGVVEAGPVRMDVERHTVAVNGEPITLPLKEFDLLEYLLRNAGRVLTRGQLI  180

Query  180  DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            DRVWGADYVGDTKTLDVHVKRLRSKIE DPA+P HL+TVRGLGYK+E 
Sbjct  181  DRVWGADYVGDTKTLDVHVKRLRSKIEPDPASPKHLITVRGLGYKIEA  228


>gi|319949621|ref|ZP_08023661.1| two-component response regulator RegX3 [Dietzia cinnamea P4]
 gi|319436708|gb|EFV91788.1| two-component response regulator RegX3 [Dietzia cinnamea P4]
Length=229

 Score =  368 bits (945),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 190/228 (84%), Positives = 202/228 (89%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDE+SLADPLAFLLRKEGFE  V  DGP+AL  F+  GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEDSLADPLAFLLRKEGFEVGVAGDGPSALESFESEGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCK+LR  SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 
Sbjct  61   TDVCKRLRMTSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGA  120

Query  121  DDDSEMSD--GVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
            + ++E  +  GVLESGPVRMD+ERH V V G  +TLPLKEFDLLEYL+RNSGRVLTRGQL
Sbjct  121  EAEAEPVEEIGVLESGPVRMDIERHTVMVRGAAVTLPLKEFDLLEYLLRNSGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWG+DYVGDTKTLDVHVKRLRSKIE DP  PVHLVTVRGLGYK E
Sbjct  181  IDRVWGSDYVGDTKTLDVHVKRLRSKIETDPGKPVHLVTVRGLGYKFE  228


>gi|326383061|ref|ZP_08204750.1| response regulator receiver [Gordonia neofelifaecis NRRL B-59395]
 gi|326198197|gb|EGD55382.1| response regulator receiver [Gordonia neofelifaecis NRRL B-59395]
Length=229

 Score =  367 bits (943),  Expect = 5e-100, Method: Compositional matrix adjust.
 Identities = 182/228 (80%), Positives = 203/228 (90%), Gaps = 2/228 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEESLADPLAFLLRKEGFEA++V DG  A++ F+R   DIVLLDLMLPG+SG
Sbjct  1    MTHVLIVEDEESLADPLAFLLRKEGFEASIVNDGSEAVSTFERVNPDIVLLDLMLPGVSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            T++CK +RA+S+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TEICKTIRAKSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  --DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
               DD + + GV+E GPVRMDV+RH V+V G  +TLPLKEFDLLEYL+RNSGRVLTR QL
Sbjct  121  VVADDEDAAIGVVEVGPVRMDVQRHTVTVAGTEVTLPLKEFDLLEYLLRNSGRVLTRSQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            IDRVWGADYVGDTKTLDVHVKRLRSK+E DP+ P HL+TVRGLGYK E
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKVEPDPSQPRHLITVRGLGYKFE  228


>gi|38233005|ref|NP_938772.1| putative two component system response regulator [Corynebacterium 
diphtheriae NCTC 13129]
 gi|38199264|emb|CAE48895.1| Putative two component system response regulator [Corynebacterium 
diphtheriae]
Length=226

 Score =  367 bits (942),  Expect = 7e-100, Method: Compositional matrix adjust.
 Identities = 183/226 (81%), Positives = 203/226 (90%), Gaps = 1/226 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MTS+L+VEDEESLADPLAFLLRKEGF+  +  DGP+AL EFDR   DIVLLDLMLPGMSG
Sbjct  1    MTSILLVEDEESLADPLAFLLRKEGFDVVIAGDGPSALVEFDRNAIDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCK+LRA SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYS+RELIARIRAVLRRGG
Sbjct  61   TDVCKRLRAVSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            +   E SD +L SG + MDVERH V+V+G+ I++PLKEFDLLEYLMRNSGRVLTRGQLID
Sbjct  121  ETIEE-SDEILGSGRIHMDVERHTVTVDGEEISMPLKEFDLLEYLMRNSGRVLTRGQLID  179

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            RVWGADYVGDTKTLDVH+KRLRSKIE +P+ P H++TVRGLGYK E
Sbjct  180  RVWGADYVGDTKTLDVHIKRLRSKIEPEPSAPCHVITVRGLGYKYE  225


>gi|258655036|ref|YP_003204192.1| winged helix family two component transcriptional regulator [Nakamurella 
multipartita DSM 44233]
 gi|258558261|gb|ACV81203.1| two component transcriptional regulator, winged helix family 
[Nakamurella multipartita DSM 44233]
Length=226

 Score =  365 bits (937),  Expect = 3e-99, Method: Compositional matrix adjust.
 Identities = 184/227 (82%), Positives = 201/227 (89%), Gaps = 1/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES+A+PLAFLLRKEGF   + T+GP AL  FDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESMAEPLAFLLRKEGFSTEIATNGPDALETFDRVGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            T+VCKQLR R +VPVIMVTA+DSEIDKVVGLELGADDY+TKPYS RELIARIRAVLRRG 
Sbjct  61   TEVCKQLRGRGAVPVIMVTAKDSEIDKVVGLELGADDYITKPYSTRELIARIRAVLRRGA  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            D D   S  VL++GPVRMDV+RHVVSV+G   +LPLKEFDLLEYL+RN+GRVLTRGQLID
Sbjct  121  DADDAHSP-VLQAGPVRMDVDRHVVSVHGVPTSLPLKEFDLLEYLIRNAGRVLTRGQLID  179

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLR+KIE DPA P +LVTVRGLGYKLE 
Sbjct  180  RVWGADYVGDTKTLDVHVKRLRAKIEPDPAEPRYLVTVRGLGYKLEA  226


>gi|227505097|ref|ZP_03935146.1| response regulator [Corynebacterium striatum ATCC 6940]
 gi|227198300|gb|EEI78348.1| response regulator [Corynebacterium striatum ATCC 6940]
Length=232

 Score =  365 bits (936),  Expect = 4e-99, Method: Compositional matrix adjust.
 Identities = 180/231 (78%), Positives = 203/231 (88%), Gaps = 5/231 (2%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT++LIVEDEESLADPLAFLLRKEGF+  + +DGP AL +F     DIVLLDLMLPGMSG
Sbjct  1    MTNILIVEDEESLADPLAFLLRKEGFDVILASDGPTALEQFANNTVDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLRA SSVPVIMVT+RDSEIDKVVGLELGADDYVTKPYS+RELIARIRAVLRRG 
Sbjct  61   TDVCKQLRATSSVPVIMVTSRDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGH  120

Query  121  DDDSE-----MSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTR  175
            D  +E     + + +LE G VRMDVERH+V V+G+ +++PLKEFDLLEYL+RN+GRVLTR
Sbjct  121  DVSAESQEEGLEEQILEGGRVRMDVERHIVMVDGEEVSMPLKEFDLLEYLLRNAGRVLTR  180

Query  176  GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            GQLIDR+WGADYVGDTKTLDVHVKRLRSKIEA+P+ P HLVTVRGLGYK E
Sbjct  181  GQLIDRIWGADYVGDTKTLDVHVKRLRSKIEAEPSRPQHLVTVRGLGYKFE  231


>gi|300857676|ref|YP_003782659.1| two-component system transcriptional regulatory protein [Corynebacterium 
pseudotuberculosis FRC41]
 gi|300685130|gb|ADK28052.1| two-component system transcriptional regulatory protein [Corynebacterium 
pseudotuberculosis FRC41]
 gi|302205415|gb|ADL09757.1| Sensory transduction protein regX3 [Corynebacterium pseudotuberculosis 
C231]
 gi|302329969|gb|ADL20163.1| Sensory transduction protein regX3 [Corynebacterium pseudotuberculosis 
1002]
 gi|308275653|gb|ADO25552.1| Putative two component system response regulator [Corynebacterium 
pseudotuberculosis I19]
 gi|341824079|gb|AEK91600.1| Sensory transduction protein regX3 [Corynebacterium pseudotuberculosis 
PAT10]
Length=231

 Score =  363 bits (932),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 184/230 (80%), Positives = 200/230 (87%), Gaps = 4/230 (1%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            M ++L+VEDEESLADPLAFLLRKEGFE  V  DGP AL EF++   DIVLLDLMLPGMSG
Sbjct  1    MITILLVEDEESLADPLAFLLRKEGFEVVVAGDGPTALVEFEKNDIDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCK+LR  SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKRLRKVSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  D----DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRG  176
            +    D  E  D +L  G VRMDVERH V+V G+ I++PLKEFDLLEYLMRNSGRVLTRG
Sbjct  121  EPQVADYEEEGDDILGGGRVRMDVERHTVTVAGENISMPLKEFDLLEYLMRNSGRVLTRG  180

Query  177  QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            QLIDR+WGADYVGDTKTLDVHVKRLRSKIE +P++P HLVTVRGLGYK E
Sbjct  181  QLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSSPKHLVTVRGLGYKFE  230


>gi|337289923|ref|YP_004628944.1| two-component system transcriptional regulator [Corynebacterium 
ulcerans BR-AD22]
 gi|334696046|gb|AEG80843.1| two-component system transcriptional regulatory protein [Corynebacterium 
ulcerans 809]
 gi|334698229|gb|AEG83025.1| two-component system transcriptional regulatory protein [Corynebacterium 
ulcerans BR-AD22]
Length=231

 Score =  360 bits (924),  Expect = 8e-98, Method: Compositional matrix adjust.
 Identities = 183/230 (80%), Positives = 200/230 (87%), Gaps = 4/230 (1%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            M ++L+VEDEESLADPLAFLLRKEGFE  V  DGP AL EF++   DIVLLDLMLPGMSG
Sbjct  1    MITILLVEDEESLADPLAFLLRKEGFEVVVAGDGPTALVEFEKNDIDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCK+LR  SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG
Sbjct  61   TDVCKRLRKVSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  121  D----DDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRG  176
            +    D  E  D +L    VRMDVERH V+V G++I++PLKEFDLLEYLMRNSGRVLTRG
Sbjct  121  EQQVADYEEDGDDILGGDRVRMDVERHTVTVAGESISMPLKEFDLLEYLMRNSGRVLTRG  180

Query  177  QLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLE  226
            QLIDR+WGADYVGDTKTLDVHVKRLRSKIE +P++P HLVTVRGLGYK E
Sbjct  181  QLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSSPKHLVTVRGLGYKFE  230


>gi|227832117|ref|YP_002833824.1| two-component system response regulator [Corynebacterium aurimucosum 
ATCC 700975]
 gi|262184032|ref|ZP_06043453.1| two-component system response regulator [Corynebacterium aurimucosum 
ATCC 700975]
 gi|227453133|gb|ACP31886.1| two-component system response regulator [Corynebacterium aurimucosum 
ATCC 700975]
Length=232

 Score =  359 bits (921),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 180/232 (78%), Positives = 199/232 (86%), Gaps = 5/232 (2%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT++LIVEDEESLADPLAFLLRKEGF+  +  DGP+AL +F     DIVLLDLMLPGMSG
Sbjct  1    MTTILIVEDEESLADPLAFLLRKEGFDVLLAPDGPSALEQFAANNVDIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVCKQLR  SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYS+RELIARIRAVLRRG 
Sbjct  61   TDVCKQLRTTSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRGQ  120

Query  121  DDDSEMS-----DGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTR  175
            D  SE +     + +LE G VRMDVERH V V G+ +++PLKEFDLLEYL+RN+GRVLTR
Sbjct  121  DASSEHAEEEPDEQILEGGRVRMDVERHTVLVAGEPVSMPLKEFDLLEYLLRNAGRVLTR  180

Query  176  GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            GQLIDR+WGADYVGDTKTLDVHVKRLRSKIEA+P+ P  LVTVRGLGYK E 
Sbjct  181  GQLIDRIWGADYVGDTKTLDVHVKRLRSKIEAEPSRPQQLVTVRGLGYKFEA  232


>gi|331699380|ref|YP_004335619.1| winged helix family two component transcriptional regulator [Pseudonocardia 
dioxanivorans CB1190]
 gi|326954069|gb|AEA27766.1| two component transcriptional regulator, winged helix family 
[Pseudonocardia dioxanivorans CB1190]
Length=229

 Score =  358 bits (918),  Expect = 4e-97, Method: Compositional matrix adjust.
 Identities = 187/229 (82%), Positives = 201/229 (88%), Gaps = 2/229 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            MT VLIVEDEES ADPLAFLLRKEGF A V T G +AL EFDR GADIVLLDLMLPGMSG
Sbjct  1    MTRVLIVEDEESFADPLAFLLRKEGFTAAVATTGQSALEEFDRNGADIVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR--  118
            TDVC+ LR+RS+VPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR  
Sbjct  61   TDVCRSLRSRSAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120

Query  119  GGDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL  178
             G  ++E   GVLE+GPVRMDV+RHVVSV G  + LPLKEFDLLEYL+RN GRVLTRGQL
Sbjct  121  EGGAEAEGGGGVLEAGPVRMDVDRHVVSVGGADVPLPLKEFDLLEYLLRNVGRVLTRGQL  180

Query  179  IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            IDRVWGADYVGDTKTLDVHVKRLRSK+E DP+ P HL+TVRGLGYK + 
Sbjct  181  IDRVWGADYVGDTKTLDVHVKRLRSKVEVDPSVPRHLITVRGLGYKFDA  229


>gi|227541629|ref|ZP_03971678.1| response regulator [Corynebacterium glucuronolyticum ATCC 51866]
 gi|227182597|gb|EEI63569.1| response regulator [Corynebacterium glucuronolyticum ATCC 51866]
Length=227

 Score =  356 bits (914),  Expect = 1e-96, Method: Compositional matrix adjust.
 Identities = 172/227 (76%), Positives = 201/227 (89%), Gaps = 0/227 (0%)

Query  1    MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG  60
            M +VLIVEDE SLA+PLAFLL+KEGF+A + TDG  AL EF++   D+VLLDLMLPGMSG
Sbjct  1    MATVLIVEDELSLAEPLAFLLKKEGFDAIIATDGRTALVEFNKNDIDLVLLDLMLPGMSG  60

Query  61   TDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGG  120
            TDVC++LR  S+VPVIMVTARD+E+DKV+GLELGADDYVTKPYS+RELIARIRAVLRRGG
Sbjct  61   TDVCRRLRQVSTVPVIMVTARDTELDKVLGLELGADDYVTKPYSSRELIARIRAVLRRGG  120

Query  121  DDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLID  180
            D D  ++D +LE G V +DVERH+V+V+G  + +PLKEFDLLEYL+RN+GRVLTRGQLID
Sbjct  121  DSDGSVADQILEGGRVSLDVERHIVTVDGQQVAMPLKEFDLLEYLLRNAGRVLTRGQLID  180

Query  181  RVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG  227
            RVWGADYVGDTKTLDVHVKRLRSKIEA+P++P  LVTVRGLGYK E 
Sbjct  181  RVWGADYVGDTKTLDVHVKRLRSKIEAEPSHPTQLVTVRGLGYKFEA  227



Lambda     K      H
   0.319    0.138    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 291076174136




  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40